Science.gov

Sample records for acceleration time history

  1. Sediment identification using free fall penetrometer acceleration-time histories

    NASA Astrophysics Data System (ADS)

    Mulukutla, Gopal K.; Huff, Lloyd C.; Melton, Jeffrey S.; Baldwin, Kenneth C.; Mayer, Larry A.

    2011-09-01

    Knowledge of physical properties of near-surface sediments is an important requirement for many studies of the seafloor. Dynamic or Free Fall Penetrometers (FFP), instrumented with accelerometers, are widely used to assess the mechanical properties of the sediment by deriving penetration resistance from the deceleration response of the probe as it impacts and embeds the seabed. Other field investigations, a priori knowledge or a very basic description of the type of sediment (such as a description of the sediment as soft, medium or hard) derived from studying the deceleration response (accelerometer-time histories) are used for sediment identification prior to the application of an appropriate strength determination model. In many cases this information is site-specific and in others the penetration resistance is overestimated due to the dilatory effects observed in sediment with an undetected grain fraction. In this study variables affecting a dynamic penetrometer-sediment interaction system are identified. Using data from field investigations and literature we found a relationship among five variables: peak acceleration, embedment depth, total embedment time, velocity of impact and grain size. This is used to formulate a sediment identification model. The model accounts for variables that may vary widely within one deployment and it can be applied to other FFPs with different physical characteristics (such as a different mass or size). This may lead to the increased use of FFP as a deployment tool for rapid in situ characterization of the seafloor.

  2. Microscale acceleration history discriminators

    DOEpatents

    Polosky, Marc A.; Plummer, David W.

    2002-01-01

    A new class of micromechanical acceleration history discriminators is claimed. These discriminators allow the precise differentiation of a wide range of acceleration-time histories, thereby allowing adaptive events to be triggered in response to the severity (or lack thereof) of an external environment. Such devices have applications in airbag activation, and other safety and surety applications.

  3. History of hadron therapy accelerators.

    PubMed

    Degiovanni, Alberto; Amaldi, Ugo

    2015-06-01

    In the last 60 years, hadron therapy has made great advances passing from a stage of pure research to a well-established treatment modality for solid tumours. In this paper the history of hadron therapy accelerators is reviewed, starting from the first cyclotrons used in the thirties for neutron therapy and passing to more modern and flexible machines used nowadays. The technical developments have been accompanied by clinical studies that allowed the selection of the tumours which are more sensitive to this type of radiotherapy. This paper aims at giving a review of the origin and the present status of hadron therapy accelerators, describing the technological basis and the continuous development of this application to medicine of instruments developed for fundamental science. At the end the present challenges are reviewed.

  4. Unique Method for Generating Design Earthquake Time Histories

    SciTech Connect

    R. E. Spears

    2008-07-01

    A method has been developed which takes a seed earthquake time history and modifies it to produce given design response spectra. It is a multi-step process with an initial scaling step and then multiple refinement steps. It is unique in the fact that both the acceleration and displacement response spectra are considered when performing the fit (which primarily improves the low frequency acceleration response spectrum accuracy). Additionally, no matrix inversion is needed. The features include encouraging the code acceleration, velocity, and displacement ratios and attempting to fit the pseudo velocity response spectrum. Also, “smoothing” is done to transition the modified time history to the seed time history at its start and end. This is done in the time history regions below a cumulative energy of 5% and above a cumulative energy of 95%. Finally, the modified acceleration, velocity, and displacement time histories are adjusted to start and end with an amplitude of zero (using Fourier transform techniques for integration).

  5. Electron accelerators: History, applications, and perspectives

    NASA Astrophysics Data System (ADS)

    Martins, M. N.; Silva, T. F.

    2014-02-01

    This paper will present an outlook on sources of radiation, focusing on electron accelerators. We will review advances that were important for the development of particle accelerators, concentrating on those that led to modern electron accelerators. Electron accelerators are multipurpose machines that deliver beams with energies spanning five orders of magnitude, and are used in applications that range from fundamental studies of particle interactions to cross-linking polymer chains in industrial plants. Each accelerator type presents specific characteristics that make it more suitable for certain applications. Our work will focus on radiation sources for medical applications, dominated by electron linacs (linear accelerators), and those used for research, field where electron rings dominate. We will outline the main technological advances that occurred in the past decades, which made possible the construction of machines fit for clinical environments. Their compactness, efficiency and reliability have been key to their acceptance in clinical applications. This outline will include advances that allowed for the construction of brighter synchrotron light sources, where the relevant beam characteristics are good optical quality and high beam current. The development of insertion devices will also be discussed, as well the development of Free Electron Lasers (FEL). We conclude the review with an outline of the new developments of electron accelerators and the expectations for Energy Recovery Linacs.

  6. SHORT ACCELERATION TIMES FROM SUPERDIFFUSIVE SHOCK ACCELERATION IN THE HELIOSPHERE

    SciTech Connect

    Perri, S.; Zimbardo, G.

    2015-12-10

    The analysis of time profiles of particles accelerated at interplanetary shocks allows particle transport properties to be inferred. The frequently observed power-law decay upstream, indeed, implies a superdiffusive particle transport when the level of magnetic field variance does not change as the time interval from the shock front increases. In this context, a superdiffusive shock acceleration (SSA) theory has been developed, allowing us to make predictions of the acceleration times. In this work we estimate for a number of interplanetary shocks, including the solar wind termination shock, the acceleration times for energetic protons in the framework of SSA and we compare the results with the acceleration times predicted by standard diffusive shock acceleration. The acceleration times due to SSA are found to be much shorter than in the classical model, and also shorter than the interplanetary shock lifetimes. This decrease of the acceleration times is due to the scale-free nature of the particle displacements in the framework of superdiffusion. Indeed, very long displacements are possible, increasing the probability for particles far from the front of the shock to return, and short displacements have a high probability of occurrence, increasing the chances for particles close to the front to cross the shock many times.

  7. Superdiffusive shock acceleration and short acceleration times at interplanetary shocks

    NASA Astrophysics Data System (ADS)

    Perri, Silvia; Zimbardo, Gaetano

    2016-04-01

    The analysis of time profiles of particles accelerated at interplanetary shock waves has shown evidence for superdiffusive transport in the upstream region. Superdiffusive transport is characterized by a mean square displacement that grows faster than linearly in time and by non Gaussian statistics for the distribution of the particle jump lengths. In the superdiffusive framework it has been shown that particle time profiles upstream of a planar shock decay as power laws, at variance with exponential particle time profiles predicted in the case of diffusive transport. A large number of interplanetary shocks, including coronal mass ejection driven shocks, exhibit energetic particle time profiles that decay as power laws far upstream. In order to take this evidence into account, we have extended the standard theory of diffusive shock acceleration to the case of particle superdiffusive transport (superdiffusive shock acceleration). This has allowed us to derive both hard energy spectral indices and short acceleration times. This new theory has been tested for a number of interplanetary shock waves, observed by the Ulysses and the ACE spacecraft, and for the termination shock. The superdiffusive shock acceleration leads to a strong reduction of the acceleration times (even of about one order of magnitude) with respect to the diffusive shock acceleration. Thus, this new framework provides a substantial advancement in the understanding of the processes of particle acceleration and particle transport, which are among the main objectives of the new Solar Probe and Solar Orbiter space missions.

  8. The overview and history of permanent magnet devices in accelerator technology

    SciTech Connect

    Kraus, R.H. Jr.

    1993-10-01

    This paper reviews the early history of accelerator development with a particular focus on the important discoveries that opened the door for the application of permanent-magnet materials to this area of science. Researchers began to use permanent-magnet materials in particle accelerators soon after the invention of the alternating gradient principle, that showed magnetic fields could be used to control the transverse envelope of charged-particle beams. Since that time, permanent-magnet materials have found wide application in the modern charged particle accelerator. The history of permanent-magnet use in accelerator physics and technology is outlined, general design considerations are presented, and material properties of concern for particle accelerator applications are discussed.

  9. A brief history of high power RF proton linear accelerators

    SciTech Connect

    Browne, J.C.

    1996-12-31

    The first mention of linear acceleration was in a paper by G. Ising in 1924 in which he postulated the acceleration of positive ions induced by spark discharges which produced electric fields in gaps between a series of {open_quotes}drift tubes{close_quotes}. Ising apparently was not able to demonstrate his concept, most likely due to the limited state of electronic devices. Ising`s work was followed by a seminal paper by R. Wideroe in 1928 in which he demonstrated the first linear accelerator. Wideroe was able to accelerate sodium or potassium ions to 50 keV of energy using drift tubes connected alternately to high frequency waves and to ground. Nuclear physics during this period was interested in accelerating protons, deuterons, electrons and alpha particles and not heavy ions like sodium or potassium. To accelerate the light ions required much higher frequencies than available at that time. So linear accelerators were not pursued heavily at that time. Research continued during the 1930s but the development of high frequency RF tubes for radar applications in World War 2 opened the potential for RF linear accelerators after the war. The Berkeley laboratory of E. 0. Lawrence under the leadership of Luis Alvarez developed a new linear proton accelerator concept that utilized drift tubes that required a full RF period to pass through as compared to the earlier concepts. This development resulted in the historic Berkeley 32 MeV proton linear accelerator which incorporated the {open_quotes}Alvarez drift tube{close_quotes} as the basic acceleration scheme using surplus 200 MHz radar components.

  10. Celebration Time: Black History Month

    ERIC Educational Resources Information Center

    Pinkney, Andrea Davis

    2008-01-01

    Nowadays, more students, teachers, and librarians are aware of African-American History Month and try to give it greater attention. However, the author questions herself if people do really "celebrate" African-American History Month or is it just something folks feel obligated to do, so they "celebrate" by displaying a collection of books about…

  11. Finite Time Shock Acceleration at Interplanetary Shocks

    NASA Astrophysics Data System (ADS)

    Channok, C.; Ruffolo, D.; Desai, M. I.; Mason, G. M.

    2004-05-01

    Observations of energetic ion acceleration at interplanetary shocks sometimes indicate a spectral rollover at ˜ 0.1 to 1 MeV nucl-1. This rollover is not well explained by finite shock width or thickness effects. At the same time, a typical timescale of diffusive shock acceleration is several days, implying that the process of shock acceleration at an interplanetary shock near Earth usually gives only a mild increase in energy to an existing seed particle population. This is consistent with a recent analysis of ACE observations that argues for a seed population at substantially higher energies than the solar wind. Therefore an explanation of typical spectra of interplanetary shock-accelerated ions requires a theory of finite-time shock acceleration, which for long times (or an unusually fast acceleration timescale) tends to the steady-state result of a power-law spectrum. We present analytic and numerical models of finite-time shock acceleration. For a given injection momentum p0, after a very short time there is only a small boost in momentum, at intermediate times the spectrum is a power law with a hump and steep cutoff at a critical momentum, and at longer times the critical momentum increases and the spectrum approaches the steady-state power law. The composition dependence of the critical momentum is different from that obtained for other cutoff mechanisms. The results are compared with observed spectra. Work in Thailand was supported by the Commission for Higher Education, the Rachadapisek Sompoj Fund of Chulalongkorn University, and the Thailand Research Fund. Work at the University of Maryland was supported by NASA contract NAS5-30927 and NASA grant PC 251428.

  12. Advanced concepts in accelerator timing control

    SciTech Connect

    Frankel, R.; Salwen, C.

    1988-01-01

    The control system for the Booster accelerator presently under construction at BNL includes a timing section with serial high speed coded data distribution, computer based encoders for both real time and field driven clocks and a method of easily tracking the performance and reliability of these timing streams. We have developed a simple method for the generation of timing which operates to produce pulses which may be repeated as desired with minimal latency.

  13. Accelerated Failure-Time Models of Graduation

    ERIC Educational Resources Information Center

    Chimka, Justin R.; Wang, Qilu

    2009-01-01

    This third article in a series describing survival analysis of engineering student retention and graduation introduces accelerated failure-time as an alternative to the Cox proportional hazards model to the context of student data. The new survival analysis of graduation data presented here assumes different distributions including exponential,…

  14. Delivering Insight The History of the Accelerated Strategic Computing Initiative

    SciTech Connect

    Larzelere II, A R

    2007-01-03

    The history of the Accelerated Strategic Computing Initiative (ASCI) tells of the development of computational simulation into a third fundamental piece of the scientific method, on a par with theory and experiment. ASCI did not invent the idea, nor was it alone in bringing it to fruition. But ASCI provided the wherewithal - hardware, software, environment, funding, and, most of all, the urgency - that made it happen. On October 1, 2005, the Initiative completed its tenth year of funding. The advances made by ASCI over its first decade are truly incredible. Lawrence Livermore, Los Alamos, and Sandia National Laboratories, along with leadership provided by the Department of Energy's Defense Programs Headquarters, fundamentally changed computational simulation and how it is used to enable scientific insight. To do this, astounding advances were made in simulation applications, computing platforms, and user environments. ASCI dramatically changed existing - and forged new - relationships, both among the Laboratories and with outside partners. By its tenth anniversary, despite daunting challenges, ASCI had accomplished all of the major goals set at its beginning. The history of ASCI is about the vision, leadership, endurance, and partnerships that made these advances possible.

  15. Reliable timing systems for computer controlled accelerators

    NASA Astrophysics Data System (ADS)

    Knott, Jürgen; Nettleton, Robert

    1986-06-01

    Over the past decade the use of computers has set new standards for control systems of accelerators with ever increasing complexity coupled with stringent reliability criteria. In fact, with very slow cycling machines or storage rings any erratic operation or timing pulse will cause the loss of precious particles and waste hours of time and effort of preparation. Thus, for the CERN linac and LEAR (Low Energy Antiproton Ring) timing system reliability becomes a crucial factor in the sense that all components must operate practically without fault for very long periods compared to the effective machine cycle. This has been achieved by careful selection of components and design well below thermal and electrical limits, using error detection and correction where possible, as well as developing "safe" decoding techniques for serial data trains. Further, consistent structuring had to be applied in order to obtain simple and flexible modular configurations with very few components on critical paths and to minimize the exchange of information to synchronize accelerators. In addition, this structuring allows the development of efficient strategies for on-line and off-line fault diagnostics. As a result, the timing system for Linac 2 has, so far, been operating without fault for three years, the one for LEAR more than one year since its final debugging.

  16. Mapping time. The calendar and its history.

    NASA Astrophysics Data System (ADS)

    Richards, E. G.

    This book, a paperback version of the 1998 hardcover edition, is an account for the general reader of the history and underlying basis of each of the most important calendars of the world, from antiquity to modern times. There are descriptions of prehistoric calendars, of those devised by the Egyptians, the Mayans, the Aztecs, and other civilizations, of the short-lived French Republican calendar.

  17. Advocacy for the Archives and History Office of the SLAC National Accelerator Laboratory: Stages and Methods

    SciTech Connect

    Deken, Jean Marie; /SLAC

    2009-06-19

    Advocating for the good of the SLAC Archives and History Office (AHO) has not been a one-time affair, nor has it been a one-method procedure. It has required taking time to ascertain the current and perhaps predict the future climate of the Laboratory, and it has required developing and implementing a portfolio of approaches to the goal of building a stronger archive program by strengthening and appropriately expanding its resources. Among the successful tools in the AHO advocacy portfolio, the Archives Program Review Committee has been the most visible. The Committee and the role it serves as well as other formal and informal advocacy efforts are the focus of this case study My remarks today will begin with a brief introduction to advocacy and outreach as I understand them, and with a description of the Archives and History Office's efforts to understand and work within the corporate culture of the SLAC National Accelerator Laboratory. I will then share with you some of the tools we have employed to advocate for the Archives and History Office programs and activities; and finally, I will talk about how well - or badly - those tools have served us over the past decade.

  18. Interstellar Mapping and Acceleration Probe (IMAP) - Its Time Has Come!

    NASA Astrophysics Data System (ADS)

    Schwadron, N.; Kasper, J. C.; Mewaldt, R. A.; Moebius, E.; Opher, M.; Spence, H. E.; Zurbuchen, T.

    2014-12-01

    Our piece of cosmic real-estate, the heliosphere, is the domain of all human existence -- an astrophysical case-history of the successful evolution of life in a habitable system. By exploring our global heliosphere and its myriad interactions, we develop key physical knowledge of the interstellar interactions that influence exoplanetary habitability as well as the distant history and destiny of our solar system and world. IBEX was the first mission to explore the global heliosphere and in concert with Voyager 1 and Voyager 2 is discovering a fundamentally new and uncharted physical domain of the outer heliosphere. The enigmatic IBEX ribbon is an unanticipated discovery demonstrating that much of what we know or think we understand about the outer heliosphere needs to be revised. The next quantum leap enabled by IMAP will open new windows on the frontier of Heliophysics at a time when the space environment is rapidly evolving. IMAP with 100 times the combined resolution and sensitivity of IBEX will discover the substructure of the IBEX ribbon and will reveal in unprecedented resolution global maps of our heliosphere. The remarkable synergy between IMAP, Voyager 1 and Voyager 2 will remain for at least the next decade as Voyager 1 pushes further into the interstellar domain and Voyager 2 moves through the heliosheath. Voyager 2 moves outward in the vicinity of the IBEX ribbon and its plasma measurements will create singular opportunities for discovery in the context of IMAP's global measurements. IMAP, like ACE before it, will be a keystone of the Heliophysics System Observatory by providing comprehensive cosmic ray, energetic particle, pickup ion, suprathermal ion, neutral atom, solar wind, solar wind heavy ion, and magnetic field observations to diagnose the changing space environment and understand the fundamental origins of particle acceleration. Thus, IMAP is a mission whose time has come. IMAP is the highest ranked next Solar Terrestrial Probe in the Decadal

  19. Faculty Speak on the Impact of Time in Accelerated Courses

    ERIC Educational Resources Information Center

    Johnson, Carrie

    2009-01-01

    Eighteen faculty members participated in this qualitative study to determine the impact of reduced seat time in accelerated courses. The findings challenge critics who believe the accelerated delivery format compromises academic quality. The participants noted the importance of students in the learning process, emphasizing the significant workload…

  20. ACCELERATORS: Timing system of HIRFL-CSR

    NASA Astrophysics Data System (ADS)

    Dong, Jin-Mei; Yuan, You-Jin; Qiao, Wei-Min; Jing, Lan; Zhang, Wei

    2009-05-01

    The national science project HIRFL-CSR has recently been officially accepted. As a cyclotron and synchrotron complex, it puts some particularly high demands on the control system. There are hundreds of pieces of equipment that need to be synchronized. An integrated timing control system is built to meet these demands. The output rate and the accuracy of the controller are 16 bit/μs. The accuracy of the time delay reaches 40 ns. The timing control system is based on a typical event distribution system, which adopts the new event generation and the distribution scheme. The scheme of the timing control system with innovation points, the architecture and the implemented method are presented in the paper.

  1. Relating Time-Dependent Acceleration and Height Using an Elevator

    ERIC Educational Resources Information Center

    Kinser, Jason M.

    2015-01-01

    A simple experiment in relating a time-dependent linear acceleration function to height is explored through the use of a smartphone and an elevator. Given acceleration as a function of time, a(t), the velocity function and position functions are determined through integration as in v(t)=? a(t) dt (1) and x(t)=? v(t) dt. Mobile devices such as…

  2. Statistics of particle time-temperature histories.

    SciTech Connect

    Hewson, John C.; Lignell, David O.; Sun, Guangyuan

    2014-10-01

    Particles in non - isothermal turbulent flow are subject to a stochastic environment tha t produces a distribution of particle time - temperature histories. This distribution is a function of the dispersion of the non - isothermal (continuous) gas phase and the distribution of particles relative to that gas phase. In this work we extend the one - dimensional turbulence (ODT) model to predict the joint dispersion of a dispersed particle phase and a continuous phase. The ODT model predicts the turbulent evolution of continuous scalar fields with a model for the cascade of fluctuations to smaller sc ales (the 'triplet map') at a rate that is a function of the fully resolved one - dimens ional velocity field . Stochastic triplet maps also drive Lagrangian particle dispersion with finite Stokes number s including inertial and eddy trajectory - crossing effect s included. Two distinct approaches to this coupling between triplet maps and particle dispersion are developed and implemented along with a hybrid approach. An 'instantaneous' particle displacement model matches the tracer particle limit and provide s an accurate description of particle dispersion. A 'continuous' particle displacement m odel translates triplet maps into a continuous velocity field to which particles respond. Particles can alter the turbulence, and modifications to the stochastic rate expr ession are developed for two - way coupling between particles and the continuous phase. Each aspect of model development is evaluated in canonical flows (homogeneous turbulence, free - shear flows and wall - bounded flows) for which quality measurements are ava ilable. ODT simulations of non - isothermal flows provide statistics for particle heating. These simulations show the significance of accurately predicting the joint statistics of particle and fluid dispersion . Inhomogeneous turbulence coupled with the in fluence of the mean flow fields on particles of varying properties alter s particle dispersion. The

  3. Statistics of particle time-temperature histories :

    SciTech Connect

    Hewson, John C.; Gin, Craig; Lignell, David O.; Sun, Guangyuan

    2013-10-01

    Progress toward predictions of the statistics of particle time-temperature histories is presented. These predictions are to be made using Lagrangian particle models within the one-dimensional turbulence (ODT) model. In the present reporting period we have further characterized the performance, behavior and capabilities of the particle dispersion models that were added to the ODT model in the first period. We have also extended the capabilities in two manners. First we provide alternate implementations of the particle transport process within ODT; within this context the original implementation is referred to as the type-I and the new implementations are referred to as the type-C and type-IC interactions. Second we have developed and implemented models for two-way coupling between the particle and fluid phase. This allows us to predict the reduced rate of turbulent mixing associated with particle dissipation of energy and similar phenomena. Work in characterizing these capabilities has taken place in homogeneous decaying turbulence, in free shear layers, in jets and in channel flow with walls, and selected results are presented.

  4. Relating Time-Dependent Acceleration and Height Using an Elevator

    NASA Astrophysics Data System (ADS)

    Kinser, Jason M.

    2015-04-01

    A simple experiment in relating a time-dependent linear acceleration function to height is explored through the use of a smartphone and an elevator. Given acceleration as a function of time1, a(t), the velocity function and position functions are determined through integration as in v (t ) =∫ a (t ) d t (1) and x (t ) =∫ v (t ) dt. Mobile devices such as smartphones or tablets have accelerometers that capture slowly evolving acceleration with respect to time and can deliver those measurements as a CSV file. A recent example measured the oscillations of the elevator as it starts its motion.2 In the application presented here the mobile device is used to estimate the height of the elevator ride. By estimating the functional form of the acceleration of an elevator ride, it is possible to estimate the height of the ride through Eqs. (1) and (2).

  5. Time and Irreversibility in AN Accelerating Universe

    NASA Astrophysics Data System (ADS)

    Romero, Gustavo E.; Pérez, Daniela

    It is a remarkable fact that all processes occurring in the observable universe are irreversible, whereas the equations through which the fundamental laws of physics are formulated are invariant under time reversal. The emergence of irreversibility from the fundamental laws has been a topic of consideration by physicists, astronomers and philosophers since Boltzmann's formulation of his famous "H" theorem. In this paper, we shall discuss some aspects of this problem and its connection with the dynamics of spacetime, within the framework of modern cosmology. We conclude that the existence of cosmological horizons allows a coupling of the global state of the universe with the local events determined through electromagnetic processes.

  6. Flutter Boundary Identification From Simulation Time Histories

    NASA Technical Reports Server (NTRS)

    Baker, Myles; Goggin, P. J.

    1997-01-01

    While there has been much recent progress in simulating nonlinear aeroelastic systems, and in predicting many of the aeroelastic phenomena of concern in transport aircraft design (i.e. transonic flutter buckets), the utility of a simulation in generating an understanding of the flutter behavior is limited. This is due in part to the high cost of generating these simulations; and the implied limitation on the number of conditions that can be analyzed, but there are also some difficulties introduced by the very nature of a simulation. Flutter engineers have traditionally worked in the frequency domain, and are accustomed to describing the flutter behavior of an airplane in terms of its V-G and V-F (or Q-G and Q-F) plots and flutter mode shapes. While the V-G and V-F plots give information about how the dynamic response of an airplane changes as the airspeed is increased, the simulation only gives information about one isolated condition (Mach, airspeed, altitude, etc.). Therefore, where a traditional flutter analysis can let the engineer determine an airspeed at which an airplane becomes unstable, while a simulation only serves as a binary check: either the airplane is fluttering at this condition, or it is not. In this document, a new technique is described in which system identification is used to easily extract modal frequencies and damping ratios from simulation time histories, and shows how the identified parameters can be used to determine the variation in frequency and dampin,o ratio as the airspeed is changed. This technique not only provides the flutter engineer with added insight into the aeroelastic behavior of the airplane, but it allows calculation of flutter mode shapes, and allows estimation of flutter boundaries while minimizing the number of simulations required.

  7. Friedman—Robertson—Walker Models with Late-Time Acceleration

    NASA Astrophysics Data System (ADS)

    Abdussattar; Prajapati, S. R.

    2011-02-01

    In order to account for the observed cosmic acceleration, a modification of the ansatz for the variation of density in Friedman—Robertson—Walker (FRW) FRW models given by Islam is proposed. The modified ansatz leads to an equation of state which corresponds to that of a variable Chaplygin gas, which in the course of evolution reduces to that of a modified generalized Chaplygin gas (MGCG) and a Chaplygin gas (CG), exhibiting late-time acceleration.

  8. Timing of Pubertal Maturation in Girls: An Integrated Life History Approach

    ERIC Educational Resources Information Center

    Ellis, Bruce J.

    2004-01-01

    Life history theory provides a metatheoretical framework for the study of pubertal timing from an evolutionary-developmental perspective. The current article reviews 5 middle-level theories-energetics theory, stress-suppression theory, psychosocial acceleration theory, paternal investment theory, and child development theory-each of which applies…

  9. Evolution of dispersal and life history interact to drive accelerating spread of an invasive species.

    PubMed

    Perkins, T Alex; Phillips, Benjamin L; Baskett, Marissa L; Hastings, Alan

    2013-08-01

    Populations on the edge of an expanding range are subject to unique evolutionary pressures acting on their life-history and dispersal traits. Empirical evidence and theory suggest that traits there can evolve rapidly enough to interact with ecological dynamics, potentially giving rise to accelerating spread. Nevertheless, which of several evolutionary mechanisms drive this interaction between evolution and spread remains an open question. We propose an integrated theoretical framework for partitioning the contributions of different evolutionary mechanisms to accelerating spread, and we apply this model to invasive cane toads in northern Australia. In doing so, we identify a previously unrecognised evolutionary process that involves an interaction between life-history and dispersal evolution during range shift. In roughly equal parts, life-history evolution, dispersal evolution and their interaction led to a doubling of distance spread by cane toads in our model, highlighting the potential importance of multiple evolutionary processes in the dynamics of range expansion.

  10. Real-time Optical Network for Accelerator Control

    SciTech Connect

    Lee, Keun

    2012-06-27

    The timing requirements of a modern accelerator complex call for several features. The first is a system for high precision relative timing among accelerator components. Stabilized fiber links have already been demonstrated to achieve sub-10 femtoseconds relative timing precision. The second is a system for timing distribution of absolute time with sufficient precision to identify a specific RF bucket. The White Rabbit technology is a promising candidate to deliver the absolute time that is linked to the GPS clock. In this study we demonstrated that these two technologies can be combined in a way that the absolute time information can be delivered to the stabilized fiber link system. This was accomplished by researching the design of the stabilized fiber and White Rabbit systems and devising adaptation modules that facilitate co-existence of both systems in the same FPGA environment. We built a prototype system using off-the-shelf products and implemented a proof-of-concept version of the FPGA firmware. The test verified that the White Rabbit features operate correctly under the stabilized fiber system environment. This work demonstrates that turn-key femtosecond timing systems with absolute time information can be built cost effectively and deployed in various accelerator environments. This will lead to many new applications in chemistry, biology and surface dynamics, to name a few.

  11. Kuss Middle School: Expanding Time to Accelerate School Improvement

    ERIC Educational Resources Information Center

    Massachusetts 2020, 2012

    2012-01-01

    In 2004, Kuss Middle School became the first school declared "Chronically Underperforming" by the state of Massachusetts. But by 2010, Kuss had transformed itself into a model for schools around the country seeking a comprehensive turnaround strategy. Kuss is using increased learning time as the primary catalyst to accelerate learning, deepen…

  12. Subjective acceleration of time experience in everyday life across adulthood.

    PubMed

    John, Dennis; Lang, Frieder R

    2015-12-01

    Most people believe that time seems to pass more quickly as they age. Building on assumptions of socioemotional selectivity theory, we investigated whether awareness that one's future lifetime is limited is associated with one's experience of time during everyday activities across adulthood in 3 studies. In the first 2 studies (Study 1: N = 608; Study 2: N = 398), participants completed a web-based version of the day reconstruction method. In Study 3 (N = 392) participants took part in a newly developed tomorrow construction method, a web-based experimental method for assessing everyday life plans. Results confirmed that older adults' subjective interpretation of everyday episodes is that these episodes pass more quickly compared with younger adults. The subjective acceleration of time experience in old age was more pronounced during productive activities than during regenerative-consumptive activities. The age differences were partly related to limited time remaining in life. In addition, subjective acceleration of time experience was associated with positive evaluations of everyday activities. Findings suggest that subjective acceleration of time in older adults' daily lives reflects an adaptation to limitations in time remaining in life. (PsycINFO Database Record

  13. Time to tenure in Spanish universities: an event history analysis.

    PubMed

    Sanz-Menéndez, Luis; Cruz-Castro, Laura; Alva, Kenedy

    2013-01-01

    Understanding how institutional incentives and mechanisms for assigning recognition shape access to a permanent job is important. This study, based on data from questionnaire survey responses and publications of 1,257 university science, biomedical and engineering faculty in Spain, attempts to understand the timing of getting a permanent position and the relevant factors that account for this transition, in the context of dilemmas between mobility and permanence faced by organizations. Using event history analysis, the paper looks at the time to promotion and the effects of some relevant covariates associated to academic performance, social embeddedness and mobility. We find that research productivity contributes to career acceleration, but that other variables are also significantly associated to a faster transition. Factors associated to the social elements of academic life also play a role in reducing the time from PhD graduation to tenure. However, mobility significantly increases the duration of the non-tenure stage. In contrast with previous findings, the role of sex is minor. The variations in the length of time to promotion across different scientific domains is confirmed, with faster career advancement for those in the Engineering and Technological Sciences compared with academics in the Biological and Biomedical Sciences. Results show clear effects of seniority, and rewards to loyalty, in addition to some measurements of performance and quality of the university granting the PhD, as key elements speeding up career advancement. Findings suggest the existence of a system based on granting early permanent jobs to those that combine social embeddedness and team integration with some good credentials regarding past and potential future performance, rather than high levels of mobility. PMID:24116199

  14. Time to Tenure in Spanish Universities: An Event History Analysis

    PubMed Central

    Sanz-Menéndez, Luis; Cruz-Castro, Laura; Alva, Kenedy

    2013-01-01

    Understanding how institutional incentives and mechanisms for assigning recognition shape access to a permanent job is important. This study, based on data from questionnaire survey responses and publications of 1,257 university science, biomedical and engineering faculty in Spain, attempts to understand the timing of getting a permanent position and the relevant factors that account for this transition, in the context of dilemmas between mobility and permanence faced by organizations. Using event history analysis, the paper looks at the time to promotion and the effects of some relevant covariates associated to academic performance, social embeddedness and mobility. We find that research productivity contributes to career acceleration, but that other variables are also significantly associated to a faster transition. Factors associated to the social elements of academic life also play a role in reducing the time from PhD graduation to tenure. However, mobility significantly increases the duration of the non-tenure stage. In contrast with previous findings, the role of sex is minor. The variations in the length of time to promotion across different scientific domains is confirmed, with faster career advancement for those in the Engineering and Technological Sciences compared with academics in the Biological and Biomedical Sciences. Results show clear effects of seniority, and rewards to loyalty, in addition to some measurements of performance and quality of the university granting the PhD, as key elements speeding up career advancement. Findings suggest the existence of a system based on granting early permanent jobs to those that combine social embeddedness and team integration with some good credentials regarding past and potential future performance, rather than high levels of mobility. PMID:24116199

  15. Extracting Time-Accurate Acceleration Vectors From Nontrivial Accelerometer Arrangements.

    PubMed

    Franck, Jennifer A; Blume, Janet; Crisco, Joseph J; Franck, Christian

    2015-09-01

    Sports-related concussions are of significant concern in many impact sports, and their detection relies on accurate measurements of the head kinematics during impact. Among the most prevalent recording technologies are videography, and more recently, the use of single-axis accelerometers mounted in a helmet, such as the HIT system. Successful extraction of the linear and angular impact accelerations depends on an accurate analysis methodology governed by the equations of motion. Current algorithms are able to estimate the magnitude of acceleration and hit location, but make assumptions about the hit orientation and are often limited in the position and/or orientation of the accelerometers. The newly formulated algorithm presented in this manuscript accurately extracts the full linear and rotational acceleration vectors from a broad arrangement of six single-axis accelerometers directly from the governing set of kinematic equations. The new formulation linearizes the nonlinear centripetal acceleration term with a finite-difference approximation and provides a fast and accurate solution for all six components of acceleration over long time periods (>250 ms). The approximation of the nonlinear centripetal acceleration term provides an accurate computation of the rotational velocity as a function of time and allows for reconstruction of a multiple-impact signal. Furthermore, the algorithm determines the impact location and orientation and can distinguish between glancing, high rotational velocity impacts, or direct impacts through the center of mass. Results are shown for ten simulated impact locations on a headform geometry computed with three different accelerometer configurations in varying degrees of signal noise. Since the algorithm does not require simplifications of the actual impacted geometry, the impact vector, or a specific arrangement of accelerometer orientations, it can be easily applied to many impact investigations in which accurate kinematics need to

  16. Late time solution for interacting scalar in accelerating spaces

    SciTech Connect

    Prokopec, Tomislav

    2015-11-01

    We consider stochastic inflation in an interacting scalar field in spatially homogeneous accelerating space-times with a constant principal slow roll parameter ε. We show that, if the scalar potential is scale invariant (which is the case when scalar contains quartic self-interaction and couples non-minimally to gravity), the late-time solution on accelerating FLRW spaces can be described by a probability distribution function (PDF) ρ which is a function of φ/H only, where φ=φ( x-vector ) is the scalar field and H=H(t) denotes the Hubble parameter. We give explicit late-time solutions for ρarrow ρ{sub ∞}(φ/H), and thereby find the order ε corrections to the Starobinsky-Yokoyama result. This PDF can then be used to calculate e.g. various n-point functions of the (self-interacting) scalar field, which are valid at late times in arbitrary accelerating space-times with ε= constant.

  17. Present and Future of Laser Accelerator 1.History and Future Prospect

    NASA Astrophysics Data System (ADS)

    Kitagawa, Yoneyoshi

    Plasma is an attractive medium for the advanced accelerator. When combined with the ultra-intense lasers, it makes the acceleration field one thousand times the field of the current microwave accelerators or the size one thousandth the size. The fields, which require now the particle accelerator, are not only the high energy physics, but also the medical, industrial and low energy material fields. In these 10 years, the laser accelerator research has advanced the electron gain of from 22 MeV to 200 MeV. Recently, it has produced 200 MeV electrons from a 2 mm-long plasma. This corresponds to 100 GV/m. On the other hand, a glass capillary has this year succeeded in making the plasma length, the acceleration length, from 2 mm to 10 mm. Mono-energetic peaks were also found. These will be the breakthrough to the second generation of the advanced accelerator development.This review introduces these topics as well as the development of the ion acceleration studies.

  18. Occupation time statistics of the random acceleration model

    NASA Astrophysics Data System (ADS)

    Joël Ouandji Boutcheng, Hermann; Bouetou Bouetou, Thomas; Burkhardt, Theodore W.; Rosso, Alberto; Zoia, Andrea; Timoleon Crepin, Kofane

    2016-05-01

    The random acceleration model is one of the simplest non-Markovian stochastic systems and has been widely studied in connection with applications in physics and mathematics. However, the occupation time and related properties are non-trivial and not yet completely understood. In this paper we consider the occupation time T + of the one-dimensional random acceleration model on the positive half-axis. We calculate the first two moments of T + analytically and also study the statistics of T + with Monte Carlo simulations. One goal of our work was to ascertain whether the occupation time T + and the time T m at which the maximum of the process is attained are statistically equivalent. For regular Brownian motion the distributions of T + and T m coincide and are given by Lévy’s arcsine law. We show that for randomly accelerated motion the distributions of T + and T m are quite similar but not identical. This conclusion follows from the exact results for the moments of the distributions and is also consistent with our Monte Carlo simulations.

  19. Late-time acceleration in higher dimensional cosmology

    SciTech Connect

    Pahwa, Isha; Choudhury, Debajyoti; Seshadri, T.R. E-mail: debajyoti.choudhury@gmail.com

    2011-09-01

    We investigate late time acceleration of the universe in higher dimensional cosmology. The content in the universe is assumed to exert pressure which is different in the normal and extra dimensions. Cosmologically viable solutions are found to exist for simple forms of the equation of state. The parameters of the model are fixed by comparing the predictions with supernovae data. While observations stipulate that the matter exerts almost vanishing pressure in the normal dimensions, we assume that, in the extra dimensions, the equation of state is of the form P∝ρ{sup 1−γ}. For appropriate choice of parameters, a late time acceleration in the universe occurs with q{sub 0} and z{sub tr} being approximately -0.46 and 0.76 respectively.

  20. The methodology study of time accelerated irradiation of elastomers

    NASA Astrophysics Data System (ADS)

    Ito, Masayuki

    2005-07-01

    The article studied the methods how to shorten the irradiation time by increasing dose rate without changing the relationship between dose versus properties of degraded samples. The samples used were nine kinds of EPDM which have different compounding formula. The different dose of Co-γ ray was exposed to the samples. The maximum dose was 2 MGy. The reference condition to be compared with two short time test conditions is irradiation of 0.33 kGy/h at room temperature. Two methods shown below were studied as the time-accelerate irradiation conditions.

  1. Krylov-subspace acceleration of time periodic waveform relaxation

    SciTech Connect

    Lumsdaine, A.

    1994-12-31

    In this paper the author uses Krylov-subspace techniques to accelerate the convergence of waveform relaxation applied to solving systems of first order time periodic ordinary differential equations. He considers the problem in the frequency domain and presents frequency dependent waveform GMRES (FDWGMRES), a member of a new class of frequency dependent Krylov-subspace techniques. FDWGMRES exhibits many desirable properties, including finite termination independent of the number of timesteps and, for certain problems, a convergence rate which is bounded from above by the convergence rate of GMRES applied to the static matrix problem corresponding to the linear time-invariant ODE.

  2. Los Alamos Neutron Science Center (LANSCE) accelerator timing system upgrade

    SciTech Connect

    Rybarcyk, L.J.; Shelley, F.E. Jr.

    1997-10-01

    The Los Alamos Neutron Science Center (LANSCE) 800 MeV proton linear accelerator (linac) operates at a maximum repetition rate of twice the AC power line frequency, i.e. 120 Hz. The start of each machine cycle occurs a fixed delay after each zero-crossing of the AC line voltage. Fluctuations in the AC line frequency and phase are therefore present on all linac timing signals. Proper beam acceleration along the linac requires that the timing signals remain well synchronized to the AC line. For neutron chopper spectrometers, e.g., PHAROS at the Manuel Lujan Jr. Neutron Scattering Center, accurate neutron energy selection requires that precise synchronization be maintained between the beam-on-target arrival time and the neutron chopper rotor position. This is most easily accomplished when the chopper is synchronized to a stable, fixed frequency signal. A new zero-crossing circuit which employs a Phase-Locked Loop (PLL) has been developed to increase the phase and frequency stability of the linac timing signals and thereby improve neutron chopper performance while simultaneously maintaining proper linac operation. Results of timing signal data analysis and modeling and a description of the PLL circuit are presented.

  3. Source Time Function of P-wave Acceleration

    NASA Astrophysics Data System (ADS)

    Chen, K. J.

    2015-12-01

    In this study, the site effect of time function of the Taiwan area will be invested. The recorded response function of a single earthquake will be calculated by Complex Demodulation. The path effect of each event-station pair will be estimated by using the forward method with a 3-D attenuation structure. After removing the path effect, the source frequency function of each single event will be obtained by averaging the whole station gotten. Using this source time function to calculate the path effect of the all stations, the theoretic received time frequency function can be obtained. The difference between this theoretic function and the recorded function is the site effect function of the single station. The characterics of the site effect in Taiwan area will be analyzed. Recalculate the path effect and remove the site effect of each station to get the new source time function of P-wave acceleration.

  4. Unifying inflation with late-time acceleration by a BIonic system

    NASA Astrophysics Data System (ADS)

    Sepehri, Alireza; Rahaman, Farook; Setare, Mohammad Reza; Pradhan, Anirudh; Capozziello, Salvatore; Sardar, Iftikar Hossain

    2015-07-01

    We propose a cosmological model that unifies inflation, deceleration and acceleration phases of expansion history by a BIonic system. At the beginning, there are k black fundamental strings that transited to the BIon configuration at a given corresponding point. Here, two coupled universes, brane and antibrane, are created interacting each other through a wormhole and inflate. With decreasing temperature, the energy of this wormhole flows into the universe branes and leads to inflation. After a short time, the wormhole evaporates, the inflation ends and a deceleration epoch starts. By approaching the brane and antibrane universes together, a tachyon is born, grows and causes the creation of a new wormhole. At this time, the brane and antibrane universes result connected again and the late-time acceleration era of the universe begins. We compare our model with previous unified phantom models and observational data obtaining some cosmological parameters like temperature in terms of time. We also find that deceleration parameter is negative during inflation and late-time acceleration epochs, while it is positive during the deceleration era. This means that the model is consistent, in principle, with cosmological observations.

  5. Accelerators, Beams And Physical Review Special Topics - Accelerators And Beams

    SciTech Connect

    Siemann, R.H.; /SLAC

    2011-10-24

    Accelerator science and technology have evolved as accelerators became larger and important to a broad range of science. Physical Review Special Topics - Accelerators and Beams was established to serve the accelerator community as a timely, widely circulated, international journal covering the full breadth of accelerators and beams. The history of the journal and the innovations associated with it are reviewed.

  6. Unique Method for Generating Design Earthquake Time History Seeds

    SciTech Connect

    R. E. Spears

    2008-07-01

    A method has been developed which takes a single seed earthquake time history and produces multiple similar seed earthquake time histories. These new time histories possess important frequency and cumulative energy attributes of the original while having a correlation less than 30% (per the ASCE/SEI 43-05 Section 2.4 [1]). They are produced by taking the fast Fourier transform of the original seed. The averaged amplitudes are then pared with random phase angles and the inverse fast Fourier transform is taken to produce a new time history. The average amplitude through time is then adjusted to encourage a similar cumulative energy curve. Next, the displacement is modified to approximate the original curve using Fourier techniques. Finally, the correlation is checked to ensure it is less than 30%. This process does not guarantee that the correlation will be less than 30% for all of a given set of new curves. It does provide a simple tool where a few additional iterations of the process should produce a set of seed earthquake time histories meeting the correlation criteria.

  7. Development of intensity compatible time-histories for dynamic analysis of structures

    NASA Astrophysics Data System (ADS)

    Klügel, Jens-Uwe; Akcay Stäuble, Sunay

    2016-04-01

    The assessment of the functionality of critical infrastructures and lifelines after an earthquake strongly depends on an accurate assessment of the degree of damage exhibited during the earthquake. Usual engineering parameters like linear-elastic response spectra or linear-elastic uniform hazard spectra in terms of spectral accelerations are not suitable for predicting damage because the process of damaging is a non-linear process. The only seismological parameter that implicitly contains the required information on the damaging impact of earthquakes is intensity. This parameter in different scales (EMS-98, MSK-64, MMI) is directly linked to physical observations including the damage of buildings. Additionally, intensity information directly captures spatial variation of ground motions related to the same or similar degree damage by construction of isoseismal lines. Therefore intensities are very suitable for predicting possible impacts of earthquakes on critical infrastructures or lifelines. For engineering applications intensity relevant information has to be converted into engineering characteristics. Because dynamic analyses (time-history analysis, frequently even nonlinear ones) became a standard approach for the design and for the validation of safety of critical infrastructures and lifelines it is reasonable to develop intensity-compatible time-histories for engineering application as an alternative to standard methods. In the paper an approach how to develop intensity-compatible time-histories from recorded time-histories is presented. Based on published international data a set of intensity compatible time-histories covering the site intensity range between intensity V and VIII (EMS scale) is developed. The time-histories developed are compared with typical time-histories derived from spectral matching of a uniform hazard spectrum from a large scale PSHA corresponding to approximately the same intensity class. For this comparison in-structure floor

  8. Electron-transfer acceleration investigated by time resolved infrared spectroscopy.

    PubMed

    Vlček, Antonín; Kvapilová, Hana; Towrie, Michael; Záliš, Stanislav

    2015-03-17

    Ultrafast electron transfer (ET) processes are important primary steps in natural and artificial photosynthesis, as well as in molecular electronic/photonic devices. In biological systems, ET often occurs surprisingly fast over long distances of several tens of angströms. Laser-pulse irradiation is conveniently used to generate strongly oxidizing (or reducing) excited states whose reactions are then studied by time-resolved spectroscopic techniques. While photoluminescence decay and UV-vis absorption supply precise kinetics data, time-resolved infrared absorption (TRIR) and Raman-based spectroscopies have the advantage of providing additional structural information and monitoring vibrational energy flows and dissipation, as well as medium relaxation, that accompany ultrafast ET. We will discuss three cases of photoinduced ET involving the Re(I)(CO)3(N,N) moiety (N,N = polypyridine) that occur much faster than would be expected from ET theories. [Re(4-N-methylpyridinium-pyridine)(CO)3(N,N)](2+) represents a case of excited-state picosecond ET between two different ligands that remains ultrafast even in slow-relaxing solvents, beating the adiabatic limit. This is caused by vibrational/solvational excitation of the precursor state and participation of high-frequency quantum modes in barrier crossing. The case of Re-tryptophan assemblies demonstrates that excited-state Trp → *Re(II) ET is accelerated from nanoseconds to picoseconds when the Re(I)(CO)3(N,N) chromophore is appended to a protein, close to a tryptophan residue. TRIR in combination with DFT calculations and structural studies reveals an interaction between the N,N ligand and the tryptophan indole. It results in partial electronic delocalization in the precursor excited state and likely contributes to the ultrafast ET rate. Long-lived vibrational/solvational excitation of the protein Re(I)(CO)3(N,N)···Trp moiety, documented by dynamic IR band shifts, could be another accelerating factor. The last

  9. From Mystics to Modern Times: A History of Craniotomy & Religion.

    PubMed

    Newman, W Christopher; Chivukula, Srinivas; Grandhi, Ramesh

    2016-08-01

    Neurosurgical treatment of diseases dates back to prehistoric times and the trephination of skulls for various maladies. Throughout the evolution of trephination, surgery and religion have been intertwined to varying degrees, a relationship that has caused both stagnation and progress. From its mystical origins in prehistoric times to its scientific progress in ancient Egypt and its resurgence as a well-validated surgical technique in modern times, trephination has been a reflection of the cultural and religious times. Herein we present a brief history of trephination as it relates religion, culture, and the evolution of neurosurgery. PMID:27150646

  10. Metabolic acceleration and the evolution of human brain size and life history.

    PubMed

    Pontzer, Herman; Brown, Mary H; Raichlen, David A; Dunsworth, Holly; Hare, Brian; Walker, Kara; Luke, Amy; Dugas, Lara R; Durazo-Arvizu, Ramon; Schoeller, Dale; Plange-Rhule, Jacob; Bovet, Pascal; Forrester, Terrence E; Lambert, Estelle V; Thompson, Melissa Emery; Shumaker, Robert W; Ross, Stephen R

    2016-05-19

    Humans are distinguished from the other living apes in having larger brains and an unusual life history that combines high reproductive output with slow childhood growth and exceptional longevity. This suite of derived traits suggests major changes in energy expenditure and allocation in the human lineage, but direct measures of human and ape metabolism are needed to compare evolved energy strategies among hominoids. Here we used doubly labelled water measurements of total energy expenditure (TEE; kcal day(-1)) in humans, chimpanzees, bonobos, gorillas and orangutans to test the hypothesis that the human lineage has experienced an acceleration in metabolic rate, providing energy for larger brains and faster reproduction without sacrificing maintenance and longevity. In multivariate regressions including body size and physical activity, human TEE exceeded that of chimpanzees and bonobos, gorillas and orangutans by approximately 400, 635 and 820 kcal day(-1), respectively, readily accommodating the cost of humans' greater brain size and reproductive output. Much of the increase in TEE is attributable to humans' greater basal metabolic rate (kcal day(-1)), indicating increased organ metabolic activity. Humans also had the greatest body fat percentage. An increased metabolic rate, along with changes in energy allocation, was crucial in the evolution of human brain size and life history. PMID:27144364

  11. Metabolic acceleration and the evolution of human brain size and life history

    PubMed Central

    Pontzer, Herman; Brown, Mary H.; Raichlen, David A.; Dunsworth, Holly; Hare, Brian; Walker, Kara; Luke, Amy; Dugas, Lara R.; Durazo-Arvizu, Ramon; Schoeller, Dale; Plange-Rhule, Jacob; Bovet, Pascal; Forrester, Terrence E.; Lambert, Estelle V.; Thompson, Melissa Emery; Shumaker, Robert W.; Ross, Stephen R.

    2016-01-01

    Humans are distinguished from the other living apes in having larger brains and an unusual life history that combines high reproductive output with slow childhood growth and exceptional longevity1. This suite of derived traits suggests major changes in energy expenditure and allocation in the human lineage, but direct measures of human and ape metabolism are needed to compare evolved energy strategies among hominoids. Here we used doubly labelled water measurements of total energy expenditure (TEE; kcal day−1) in humans, chimpanzees, bonobos, gorillas and orangutans to test the hypothesis that the human lineage has experienced an acceleration in metabolic rate, providing energy for larger brains and faster reproduction without sacrificing maintenance and longevity. In multivariate regressions including body size and physical activity, human TEE exceeded that of chimpanzees and bonobos, gorillas and orangutans by approximately 400, 635 and 820 kcal day−1, respectively, readily accommodating the cost of humans' greater brain size and reproductive output. Much of the increase in TEE is attributable to humans' greater basal metabolic rate (kcal day−1), indicating increased organ metabolic activity. Humans also had the greatest body fat percentage. An increased metabolic rate, along with changes in energy allocation, was crucial in the evolution of human brain size and life history. PMID:27144364

  12. Metabolic acceleration and the evolution of human brain size and life history.

    PubMed

    Pontzer, Herman; Brown, Mary H; Raichlen, David A; Dunsworth, Holly; Hare, Brian; Walker, Kara; Luke, Amy; Dugas, Lara R; Durazo-Arvizu, Ramon; Schoeller, Dale; Plange-Rhule, Jacob; Bovet, Pascal; Forrester, Terrence E; Lambert, Estelle V; Thompson, Melissa Emery; Shumaker, Robert W; Ross, Stephen R

    2016-05-04

    Humans are distinguished from the other living apes in having larger brains and an unusual life history that combines high reproductive output with slow childhood growth and exceptional longevity. This suite of derived traits suggests major changes in energy expenditure and allocation in the human lineage, but direct measures of human and ape metabolism are needed to compare evolved energy strategies among hominoids. Here we used doubly labelled water measurements of total energy expenditure (TEE; kcal day(-1)) in humans, chimpanzees, bonobos, gorillas and orangutans to test the hypothesis that the human lineage has experienced an acceleration in metabolic rate, providing energy for larger brains and faster reproduction without sacrificing maintenance and longevity. In multivariate regressions including body size and physical activity, human TEE exceeded that of chimpanzees and bonobos, gorillas and orangutans by approximately 400, 635 and 820 kcal day(-1), respectively, readily accommodating the cost of humans' greater brain size and reproductive output. Much of the increase in TEE is attributable to humans' greater basal metabolic rate (kcal day(-1)), indicating increased organ metabolic activity. Humans also had the greatest body fat percentage. An increased metabolic rate, along with changes in energy allocation, was crucial in the evolution of human brain size and life history.

  13. Life-history syndromes: integrating dispersal through space and time.

    PubMed

    Buoro, Mathieu; Carlson, Stephanie M

    2014-06-01

    Recent research has highlighted interdependencies between dispersal and other life-history traits, i.e. dispersal syndromes, thereby revealing constraints on the evolution of dispersal and opportunities for improved ability to predict dispersal by considering suites of dispersal-related traits. This review adds to the growing list of life-history traits linked to spatial dispersal by emphasising the interdependence between dispersal through space and time, i.e. life-history diversity that distributes individuals into separate reproductive events. We reviewed the literature that has simultaneously investigated spatial and temporal dispersal to examine the prediction that traits of these two dispersal strategies are negatively correlated. Our results suggest that negative covariation is widely anticipated from theory. Empirical studies often reported evidence of weak negative covariation, although more complicated patterns were also evident, including across levels of biological organisation. Existing literature has largely focused on plants with dormancy capability, one or two phases of the dispersal process (emigration and/or transfer) and a single level of biological organisation (theory: individual; empirical: species). We highlight patterns of covariation across levels of organisation and conclude with a discussion of the consequences of dispersal through space and time and future research areas that should improve our understanding of dispersal-related life-history syndromes.

  14. The operant reserve: a computer simulation in (accelerated) real time.

    PubMed

    Catania, A Charles

    2005-05-31

    In Skinner's Reflex Reserve theory, reinforced responses added to a reserve depleted by responding. It could not handle the finding that partial reinforcement generated more responding than continuous reinforcement, but it would have worked if its growth had depended not just on the last response but also on earlier responses preceding a reinforcer, each weighted by delay. In that case, partial reinforcement generates steady states in which reserve decrements produced by responding balance increments produced when reinforcers follow responding. A computer simulation arranged schedules for responses produced with probabilities proportional to reserve size. Each response subtracted a fixed amount from the reserve and added an amount weighted by the reciprocal of the time to the next reinforcer. Simulated cumulative records and quantitative data for extinction, random-ratio, random-interval, and other schedules were consistent with those of real performances, including some effects of history. The model also simulated rapid performance transitions with changed contingencies that did not depend on molar variables or on differential reinforcement of inter-response times. The simulation can be extended to inhomogeneous contingencies by way of continua of reserves arrayed along response and time dimensions, and to concurrent performances and stimulus control by way of different reserves created for different response classes. PMID:15845312

  15. The operant reserve: a computer simulation in (accelerated) real time.

    PubMed

    Catania, A Charles

    2005-05-31

    In Skinner's Reflex Reserve theory, reinforced responses added to a reserve depleted by responding. It could not handle the finding that partial reinforcement generated more responding than continuous reinforcement, but it would have worked if its growth had depended not just on the last response but also on earlier responses preceding a reinforcer, each weighted by delay. In that case, partial reinforcement generates steady states in which reserve decrements produced by responding balance increments produced when reinforcers follow responding. A computer simulation arranged schedules for responses produced with probabilities proportional to reserve size. Each response subtracted a fixed amount from the reserve and added an amount weighted by the reciprocal of the time to the next reinforcer. Simulated cumulative records and quantitative data for extinction, random-ratio, random-interval, and other schedules were consistent with those of real performances, including some effects of history. The model also simulated rapid performance transitions with changed contingencies that did not depend on molar variables or on differential reinforcement of inter-response times. The simulation can be extended to inhomogeneous contingencies by way of continua of reserves arrayed along response and time dimensions, and to concurrent performances and stimulus control by way of different reserves created for different response classes.

  16. Time-dependent Electron Acceleration in Blazar Transients: X-Ray Time Lags and Spectral Formation

    NASA Astrophysics Data System (ADS)

    Lewis, Tiffany R.; Becker, Peter A.; Finke, Justin D.

    2016-06-01

    Electromagnetic radiation from blazar jets often displays strong variability, extending from radio to γ-ray frequencies. In a few cases, this variability has been characterized using Fourier time lags, such as those detected in the X-rays from Mrk 421 using BeppoSAX. The lack of a theoretical framework to interpret the data has motivated us to develop a new model for the formation of the X-ray spectrum and the time lags in blazar jets based on a transport equation including terms describing stochastic Fermi acceleration, synchrotron losses, shock acceleration, adiabatic expansion, and spatial diffusion. We derive the exact solution for the Fourier transform of the electron distribution and use it to compute the Fourier transform of the synchrotron radiation spectrum and the associated X-ray time lags. The same theoretical framework is also used to compute the peak flare X-ray spectrum, assuming that a steady-state electron distribution is achieved during the peak of the flare. The model parameters are constrained by comparing the theoretical predictions with the observational data for Mrk 421. The resulting integrated model yields, for the first time, a complete first-principles physical explanation for both the formation of the observed time lags and the shape of the peak flare X-ray spectrum. It also yields direct estimates of the strength of the shock and the stochastic magnetohydrodynamical wave acceleration components in the Mrk 421 jet.

  17. Late time cosmic acceleration from natural infrared cutoff

    NASA Astrophysics Data System (ADS)

    Gorji, Mohammad Ali

    2016-09-01

    In this paper, inspired by the ultraviolet deformation of the Friedmann-Lemaître-Robertson-Walker geometry in loop quantum cosmology, we formulate an infrared-modified cosmological model. We obtain the associated deformed Friedmann and Raychaudhuri equations and we show that the late time cosmic acceleration can be addressed by the infrared corrections. As a particular example, we applied the setup to the case of matter dominated universe. This model has the same number of parameters as ΛCDM, but a dynamical dark energy generates in the matter dominated era at the late time. According to our model, as the universe expands, the energy density of the cold dark matter dilutes and when the Hubble parameter approaches to its minimum, the infrared effects dominate such that the effective equation of state parameter smoothly changes from weff = 0 to weff = - 2. Interestingly and nontrivially, the unstable de Sitter phase with weff = - 1 is corresponding to Ωm =Ωd = 0.5 and the universe crosses the phantom divide from the quintessence phase with weff > - 1 and Ωm >Ωd to the phantom phase with weff < - 1 and Ωm <Ωd which shows that the model is observationally viable. The results show that the universe finally ends up in a big rip singularity for a finite time proportional to the inverse of the minimum of the Hubble parameter. Moreover, we consider the dynamical stability of the model and we show that the universe starts from the matter dominated era at the past attractor with weff = 0 and ends up in a future attractor at the big rip with weff = - 2.

  18. Convergence Acceleration for Multistage Time-Stepping Schemes

    NASA Technical Reports Server (NTRS)

    Swanson, R. C.; Turkel, Eli L.; Rossow, C-C; Vasta, V. N.

    2006-01-01

    The convergence of a Runge-Kutta (RK) scheme with multigrid is accelerated by preconditioning with a fully implicit operator. With the extended stability of the Runge-Kutta scheme, CFL numbers as high as 1000 could be used. The implicit preconditioner addresses the stiffness in the discrete equations associated with stretched meshes. Numerical dissipation operators (based on the Roe scheme, a matrix formulation, and the CUSP scheme) as well as the number of RK stages are considered in evaluating the RK/implicit scheme. Both the numerical and computational efficiency of the scheme with the different dissipation operators are discussed. The RK/implicit scheme is used to solve the two-dimensional (2-D) and three-dimensional (3-D) compressible, Reynolds-averaged Navier-Stokes equations. In two dimensions, turbulent flows over an airfoil at subsonic and transonic conditions are computed. The effects of mesh cell aspect ratio on convergence are investigated for Reynolds numbers between 5.7 x 10(exp 6) and 100.0 x 10(exp 6). Results are also obtained for a transonic wing flow. For both 2-D and 3-D problems, the computational time of a well-tuned standard RK scheme is reduced at least a factor of four.

  19. Timing of recent accelerations of Pine Island Glacier, Antarctica

    USGS Publications Warehouse

    Joughin, I.; Rignot, E.; Rosanova, C.E.; Lucchitta, B.K.; Bohlander, J.

    2003-01-01

    We have used Interferometric Synthetic Aperture Radar (InSAR) data and sequential Landsat imagery to identify and temporally constrain two acceleration events on Pine Island Glacier (PIG). These two events are separated by a period of at least seven years (1987 - 1994). The change in discharge between two flux gates indicates that the majority of the increase in discharge associated with the second acceleration originates well inland (>80 km) from the grounding line. An analysis indicates that changes in driving stress consistent with observed thinning rates are sufficient in magnitude to explain much of the acceleration.

  20. Visual reaction times during prolonged angular acceleration parallel the subjective perception of rotation

    NASA Technical Reports Server (NTRS)

    Mattson, D. L.

    1975-01-01

    The effect of prolonged angular acceleration on choice reaction time to an accelerating visual stimulus was investigated, with 10 commercial airline pilots serving as subjects. The pattern of reaction times during and following acceleration was compared with the pattern of velocity estimates reported during identical trials. Both reaction times and velocity estimates increased at the onset of acceleration, declined prior to the termination of acceleration, and showed an aftereffect. These results are inconsistent with the torsion-pendulum theory of semicircular canal function and suggest that the vestibular adaptation is of central origin.

  1. Solar Energetic Particle Acceleration/Injection Time Profiles: Much Better Observed in the Inner Heliosphere

    NASA Astrophysics Data System (ADS)

    Roelof, E. C.; Lario, D.; Haggerty, D. K.

    2006-12-01

    We have argued that during the beam-like anisotropic phase of solar energetic particle (SEP) events, the history of the field-aligned unidirectional intensity is essentially that of the injection history at the Sun (shifted backwards by the scatter-free transit time). We have concentrated so far mainly on the injection timing relative to that of solar electromagnetic signatures, because the onset of the first-arriving particles can be delayed by only a fraction of their scatter-free transit time by interplanetary scattering (i.e., 10 min to 1AU for relativistic particles). However, there is much more information than just the onset time contained in the field- aligned intensity time profile throughout the beam-like phase; it must echo that of the actual solar injection history. We have recently classified the intensity time profiles during the duration of the beam-like anisotropies of ACE/EPAM near-relativistic electrons into three broad categories: 1) Spikes (rapid and equal rise and decay); 2) Pulses (rapid rise, slower decay); and 3) Ramps (rapid rise followed by a plateau). These classes indicate a wide range (and possibly different mechanisms) for SEP acceleration/injection. The beam- like anisotropic phase ends when a sufficient number of particles have been backscattered from beyond 1AU where propagation is no longer essentially scatter-free (as it usually is inside 1AU). Preliminary estimates of the time difference between the event beam onset and the first arrival of back-scattered particles yield about 10 min or more. This gives us a 10 min window for an unambiguous view of the injection history (although we can actually extract considerably more of the injection history even in the presence of back-scatter). The >10 min elapsed time for relativistic particles places this back-scattering region somewhere roughly beyond 1.3 AU (a field-aligned round-trip distance of >1.0 beyond 1 AU). Now imagine a spacecraft like one of the Sentinels, Solar Orbiter, or

  2. Conceptualizing time preference: a life-history analysis.

    PubMed

    Copping, Lee T; Campbell, Anne; Muncer, Steven

    2014-09-29

    Life-history theory (LHT) has drawn upon the concept of "time preference" as a psychological mechanism for the development of fast and slow strategies. However, the conceptual and empirical nature of this mechanism is ill-defined. This study compared four traits commonly used as measures of "time preference" (impulsivity, sensation seeking, future orientation and delay discounting) and evaluated their relationship to variables associated with life-history strategies (aggressive behavior and mating attitudes, biological sex, pubertal timing, victimization, and exposure to aggression in the environment). Results indicated that only sensation seeking consistently showed all the predicted associations, although impulsivity, future orientation, and delay discounting showed some significant associations. A unidimensional higher-order factor of "time preference" did not adequately fit the data and lacked structural invariance across age and sex, suggesting that personality traits associated with LHT do not represent a global trait. We discuss the use of personality traits as measures in LHT and suggest that greater caution and clarity is required when conceptualizing this construct in future work.

  3. TIME-DEPENDENT STOCHASTIC ACCELERATION MODEL FOR FERMI BUBBLES

    SciTech Connect

    Sasaki, Kento; Asano, Katsuaki; Terasawa, Toshio E-mail: asanok@icrr.u-tokyo.ac.jp

    2015-12-01

    We study stochastic acceleration models for the Fermi bubbles. Turbulence is excited just behind the shock front via Kelvin–Helmholtz, Rayleigh–Taylor, or Richtmyer–Meshkov instabilities, and plasma particles are continuously accelerated by the interaction with the turbulence. The turbulence gradually decays as it goes away from the shock fronts. Adopting a phenomenological model for the stochastic acceleration, we explicitly solve the temporal evolution of the particle energy distribution in the turbulence. Our results show that the spatial distribution of high-energy particles is different from those for a steady solution. We also show that the contribution of electrons that escaped from the acceleration regions significantly softens the photon spectrum. The photon spectrum and surface brightness profile are reproduced by our models. If the escape efficiency is very high, the radio flux from the escaped low-energy electrons can be comparable to that of the WMAP haze. We also demonstrate hadronic models with the stochastic acceleration, but they are unlikely in the viewpoint of the energy budget.

  4. An internally consistent gamma ray burst time history phenomenology

    NASA Technical Reports Server (NTRS)

    Cline, T. L.

    1985-01-01

    A phenomenology for gamma ray burst time histories is outlined. Order of their generally chaotic appearance is attempted, based on the speculation that any one burst event can be represented above 150 keV as a superposition of similarly shaped increases of varying intensity. The increases can generally overlap, however, confusing the picture, but a given event must at least exhibit its own limiting characteristic rise and decay times if the measurements are made with instruments having adequate temporal resolution. Most catalogued observations may be of doubtful or marginal utility to test this hypothesis, but some time histories from Helios-2, Pioneer Venus Orbiter and other instruments having one-to several-millisecond capabilities appear to provide consistency. Also, recent studies of temporally resolved Solar Maximum Mission burst energy spectra are entirely compatible with this picture. The phenomenology suggested here, if correct, may assist as an analytic tool for modelling of burst processes and possibly in the definition of burst source populations.

  5. The Adaptive Basis of Psychosocial Acceleration: Comment on beyond Mental Health, Life History Strategies Articles

    ERIC Educational Resources Information Center

    Nettle, Daniel; Frankenhuis, Willem E.; Rickard, Ian J.

    2012-01-01

    Four of the articles published in this special section of "Developmental Psychology" build on and refine psychosocial acceleration theory. In this short commentary, we discuss some of the adaptive assumptions of psychosocial acceleration theory that have not received much attention. Psychosocial acceleration theory relies on the behavior of…

  6. Accelerating Child Survival and Development in Dark Times.

    ERIC Educational Resources Information Center

    Grant, James P.

    Measures were proposed that would enable UNICEF, in association with others and despite prevailing difficult economic circumstances, to more effectively bring well-being and hope to hundreds of millions of children. Specific proposals were designed to help most countries accelerate child survival and development. Most particularly, it was…

  7. Cosmic Times: Engaging Students in Astronomy through History and Journalism

    NASA Astrophysics Data System (ADS)

    Lochner, James C.; Mattson, B. J.

    2010-03-01

    Cosmic Times tells the story of how our understanding of the nature of the universe has changed over the past 100 years. Designed to fulfill the need for quality science literature in the classroom, Cosmic Times takes the form of six posters, each mimicking the front page of a newspaper at a key point in this history, with articles describing the discoveries. These milestones include the confirmation of Einstein's theory of gravity, Hubble's evidence for an expanding universe, the detection of the microwave background, and finally the discovery of dark energy. Telling this story also involves tracing astronomer's efforts to determine the size of the universe, understand the nature of supernovae, and comprehend the expansion of the universe. Through the scope of this history, students experience the process of science and how new technology and data change our ideas. The posters are accompanied by 28 lessons for grades 7-12, designed by scientists and teachers and field-tested by third-party teachers in rural communities. The lessons teach the science concepts behind the discoveries, the process of science, and skills for science literacy. To facilitate these lessons and meet student's individual science literacy needs, the articles are also available in two newsletter versions: one with the same articles as on the posters, the second at a slightly lower reading level. In addition, lessons include cross-curricular activities which explore the times and social circumstances of the discoveries. All these materials, including an on-line Teacher Guide, are available on the Cosmic Times website, http://cosmictimes.gsfc.nasa.gov/. In this presentation, we shall describe how Cosmic Times uses journalistic storytelling to create a rich experience based on science literacy to teach fundamental science concepts. We will show how framing the story as historic news articles illustrates the process of science and opens up opportunities for multidisciplinary lessons.

  8. Merging metadynamics into hyperdynamics: accelerated molecular simulations reaching time scales from microseconds to seconds.

    PubMed

    Bal, Kristof M; Neyts, Erik C

    2015-10-13

    The hyperdynamics method is a powerful tool to simulate slow processes at the atomic level. However, the construction of an optimal hyperdynamics potential is a task that is far from trivial. Here, we propose a generally applicable implementation of the hyperdynamics algorithm, borrowing two concepts from metadynamics. First, the use of a collective variable (CV) to represent the accelerated dynamics gives the method a very large flexibility and simplicity. Second, a metadynamics procedure can be used to construct a suitable history-dependent bias potential on-the-fly, effectively turning the algorithm into a self-learning accelerated molecular dynamics method. This collective variable-driven hyperdynamics (CVHD) method has a modular design: both the local system properties on which the bias is based, as well as the characteristics of the biasing method itself, can be chosen to match the needs of the considered system. As a result, system-specific details are abstracted from the biasing algorithm itself, making it extremely versatile and transparent. The method is tested on three model systems: diffusion on the Cu(001) surface and nickel-catalyzed methane decomposition, as examples of “reactive” processes with a bond-length-based CV, and the folding of a long polymer-like chain, using a set of dihedral angles as a CV. Boost factors up to 109, corresponding to a time scale of seconds, could be obtained while still accurately reproducing correct dynamics.

  9. Effects of angular acceleration on man - Choice reaction time using visual and rotary motion information

    NASA Technical Reports Server (NTRS)

    Clark, B.; Stewart, J. D.

    1974-01-01

    This experiment was concerned with the effects of rotary acceleration on choice reaction time (RTc) to the motion of a luminous line on a cathode-ray tube. Specifically, it compared the (RTc) to rotary acceleration alone, visual acceleration alone, and simultaneous, double stimulation by both rotary and visual acceleration. Thirteen airline pilots were rotated about an earth-vertical axis in a precision rotation device while they observed a vertical line. The stimuli were 7 rotary and visual accelerations which were matched for rise time. The pilot responded as quickly as possible by displacing a vertical controller to the right or left. The results showed a decreasing (RTc) with increasing acceleration for all conditions, while the (RTc) to rotary motion alone was substantially longer than for all other conditions. The (RTc) to the double stimulation was significantly longer than that for visual acceleration alone.

  10. Evolution of the single-mode Rayleigh-Taylor instability under the influence of time-dependent accelerations.

    PubMed

    Ramaprabhu, P; Karkhanis, V; Banerjee, R; Varshochi, H; Khan, M; Lawrie, A G W

    2016-01-01

    From nonlinear models and direct numerical simulations we report on several findings of relevance to the single-mode Rayleigh-Taylor (RT) instability driven by time-varying acceleration histories. The incompressible, direct numerical simulations (DNSs) were performed in two (2D) and three dimensions (3D), and at a range of density ratios of the fluid combinations (characterized by the Atwood number). We investigated several acceleration histories, including acceleration profiles of the general form g(t)∼t^{n}, with n≥0 and acceleration histories reminiscent of the linear electric motor experiments. For the 2D flow, results from numerical simulations compare well with a 2D potential flow model and solutions to a drag-buoyancy model reported as part of this work. When the simulations are extended to three dimensions, bubble and spike growth rates are in agreement with the so-called level 2 and level 3 models of Mikaelian [K. O. Mikaelian, Phys. Rev. E 79, 065303(R) (2009)10.1103/PhysRevE.79.065303], and with corresponding 3D drag-buoyancy model solutions derived in this article. Our generalization of the RT problem to study variable g(t) affords us the opportunity to investigate the appropriate scaling for bubble and spike amplitudes under these conditions. We consider two candidates, the displacement Z and width s^{2}, but find the appropriate scaling is dependent on the density ratios between the fluids-at low density ratios, bubble and spike amplitudes are explained by both s^{2} and Z, while at large density differences the displacement collapses the spike data. Finally, for all the acceleration profiles studied here, spikes enter a free-fall regime at lower Atwood numbers than predicted by all the models. PMID:26871165

  11. Evolution of the single-mode Rayleigh-Taylor instability under the influence of time-dependent accelerations

    NASA Astrophysics Data System (ADS)

    Ramaprabhu, P.; Karkhanis, V.; Banerjee, R.; Varshochi, H.; Khan, M.; Lawrie, A. G. W.

    2016-01-01

    From nonlinear models and direct numerical simulations we report on several findings of relevance to the single-mode Rayleigh-Taylor (RT) instability driven by time-varying acceleration histories. The incompressible, direct numerical simulations (DNSs) were performed in two (2D) and three dimensions (3D), and at a range of density ratios of the fluid combinations (characterized by the Atwood number). We investigated several acceleration histories, including acceleration profiles of the general form g (t ) ˜tn , with n ≥0 and acceleration histories reminiscent of the linear electric motor experiments. For the 2D flow, results from numerical simulations compare well with a 2D potential flow model and solutions to a drag-buoyancy model reported as part of this work. When the simulations are extended to three dimensions, bubble and spike growth rates are in agreement with the so-called level 2 and level 3 models of Mikaelian [K. O. Mikaelian, Phys. Rev. E 79, 065303(R) (2009), 10.1103/PhysRevE.79.065303], and with corresponding 3D drag-buoyancy model solutions derived in this article. Our generalization of the RT problem to study variable g (t ) affords us the opportunity to investigate the appropriate scaling for bubble and spike amplitudes under these conditions. We consider two candidates, the displacement Z and width s2, but find the appropriate scaling is dependent on the density ratios between the fluids—at low density ratios, bubble and spike amplitudes are explained by both s2 and Z , while at large density differences the displacement collapses the spike data. Finally, for all the acceleration profiles studied here, spikes enter a free-fall regime at lower Atwood numbers than predicted by all the models.

  12. Evolution of the single-mode Rayleigh-Taylor instability under the influence of time-dependent accelerations.

    PubMed

    Ramaprabhu, P; Karkhanis, V; Banerjee, R; Varshochi, H; Khan, M; Lawrie, A G W

    2016-01-01

    From nonlinear models and direct numerical simulations we report on several findings of relevance to the single-mode Rayleigh-Taylor (RT) instability driven by time-varying acceleration histories. The incompressible, direct numerical simulations (DNSs) were performed in two (2D) and three dimensions (3D), and at a range of density ratios of the fluid combinations (characterized by the Atwood number). We investigated several acceleration histories, including acceleration profiles of the general form g(t)∼t^{n}, with n≥0 and acceleration histories reminiscent of the linear electric motor experiments. For the 2D flow, results from numerical simulations compare well with a 2D potential flow model and solutions to a drag-buoyancy model reported as part of this work. When the simulations are extended to three dimensions, bubble and spike growth rates are in agreement with the so-called level 2 and level 3 models of Mikaelian [K. O. Mikaelian, Phys. Rev. E 79, 065303(R) (2009)10.1103/PhysRevE.79.065303], and with corresponding 3D drag-buoyancy model solutions derived in this article. Our generalization of the RT problem to study variable g(t) affords us the opportunity to investigate the appropriate scaling for bubble and spike amplitudes under these conditions. We consider two candidates, the displacement Z and width s^{2}, but find the appropriate scaling is dependent on the density ratios between the fluids-at low density ratios, bubble and spike amplitudes are explained by both s^{2} and Z, while at large density differences the displacement collapses the spike data. Finally, for all the acceleration profiles studied here, spikes enter a free-fall regime at lower Atwood numbers than predicted by all the models.

  13. Minimum time acceleration of aircraft turbofan engines by using an algorithm based on nonlinear programming

    NASA Technical Reports Server (NTRS)

    Teren, F.

    1977-01-01

    Minimum time accelerations of aircraft turbofan engines are presented. The calculation of these accelerations was made by using a piecewise linear engine model, and an algorithm based on nonlinear programming. Use of this model and algorithm allows such trajectories to be readily calculated on a digital computer with a minimal expenditure of computer time.

  14. Performing dynamic time history analyses by extension of the response spectrum method

    SciTech Connect

    Hulbert, G.M.

    1983-01-01

    A method is presented to calculate the dynamic time history response of finite element models using results from response spectrum analyses. The proposed ''modified'' time history method does not represent a new mathematical approach to dynamic analysis but suggests a more efficient ordering of the analytical equations and procedures. The modified time history method is considerably faster and less expensive to use than normal time history methods. This paper presents the theory and implementation of the modified time history approach along with comparisons of the modified and normal time history methods for a prototypic seismic piping design problem.

  15. Cosmic Times: Engaging Students in Science through History and Journalism

    NASA Astrophysics Data System (ADS)

    Lochner, J. C.; Mattson, B. J.

    2009-12-01

    Cosmic Times tells the story of how our understanding of the nature of the universe has changed over the past 100 years. Designed to fulfill the need for quality science literature in the classroom, Cosmic Times takes the form of six posters, each mimicking the front page of a newspaper at a key point in this history, with articles describing the discoveries. These milestones include the confirmation of Einstein’s theory of gravity, Hubble’s evidence for an expanding universe, the detection of the microwave background, and finally the discovery of dark energy. Telling this story also involves tracing astronomer’s efforts to determine the size of the universe, understand the nature of supernovae, and comprehend the expansion of the universe. Through the scope of this history, students experience the process of science and how new technology and data change our ideas. The posters are accompanied by 28 lessons, designed for grades 7-12 by scientists and teachers and field-tested by third-party teachers in rural communities. The lessons teach the science concepts behind the discoveries, the process of science, and skills for science literacy. To facilitate these lessons and meet student’s individual science literacy needs, the articles are also available in two newsletter versions: one with the same articles as on the posters, the second at a slightly lower reading level. In addition, lessons include cross-curricular activities which explore the times and social circumstances of the discoveries. In a capstone lesson, students write and design the 2019 edition of Cosmic Times, not only predicting what we will know in the future, but also applying expository writing skills. In addition, an on-line Teacher Guide provides background material for all the articles. All these materials are available on the Cosmic Times website, http://cosmictimes.gsfc.nasa.gov/. In this presentation, we shall describe how Cosmic Times uses a journalistic storytelling approach to

  16. Rotary acceleration of a subject inhibits choice reaction time to motion in peripheral vision

    NASA Technical Reports Server (NTRS)

    Borkenhagen, J. M.

    1974-01-01

    Twelve pilots were tested in a rotation device with visual simulation, alone and in combination with rotary stimulation, in experiments with variable levels of acceleration and variable viewing angles, in a study of the effect of S's rotary acceleration on the choice reaction time for an accelerating target in peripheral vision. The pilots responded to the direction of the visual motion by moving a hand controller to the right or left. Visual-plus-rotary stimulation required a longer choice reaction time, which was inversely related to the level of acceleration and directly proportional to the viewing angle.

  17. An accelerated failure time model for investigating pedestrian crossing behavior and waiting times at signalized intersections.

    PubMed

    Yang, Xiaobao; Abdel-Aty, Mohamed; Huan, Mei; Peng, Yichuan; Gao, Ziyou

    2015-09-01

    The waiting process is crucial to pedestrians in the street-crossing behavior. Once pedestrians terminate their waiting behavior during the red light period, they would cross against the red light and put themselves in danger. A joint hazard-based duration model is developed to investigate the effect of various covariates on pedestrian crossing behavior and to estimate pedestrian waiting times at signalized intersections. A total of 1181 pedestrians approaching the intersections during red light periods were observed in Beijing, China. Pedestrian crossing behaviors are classified into immediate crossing behavior and waiting behavior. The probability and effect of various covariates for pedestrians' immediate crossing behavior are identified by a logit model. Four accelerated failure time duration models based on the exponential, Weibull, lognormal and log-logistic distributions are proposed to examine the significant risk factors affecting duration times for pedestrians' waiting behavior. A joint duration model is developed to estimate pedestrian waiting times. Moreover, unobserved heterogeneity is considered in the proposed model. The results indicate that the Weibull AFT model with shared frailty is appropriate for modelling pedestrian waiting durations. Failure to account for heterogeneity would significantly underestimate the effects of covariates on waiting duration times. The proposed model provides a better understanding of pedestrian crossing behavior and more accurate estimation of pedestrian waiting times. It may be applicable in traffic system analysis in developing countries with high flow of mixed traffic.

  18. Time-scale bias in evidence for anthropogenic acceleration of soil erosion and floodplain accretion

    NASA Astrophysics Data System (ADS)

    Willenbring, J. K.; Hoffmann, T.; Sadler, P.; Kaplan, J. O.; Chiverrell, R. C.; Erkens, G.; von Blanckenburg, F.

    2014-12-01

    The claim that humans modify the landscape more dramatically than any previous geological agent has impacts for river restoration, conservation and models of both nutrient- and carbon-cycling. This view of extreme sediment mobilization driven by human activities is largely based on data, which unfortunately are measured over discrepant timescales that can introduce bias. Comparing denudation rates discerned from cosmogenic nuclides as 'baseline' or 'natural' rates with continent-scale sediment export rates over modern timescales reveals that most cosmogenic nuclide-based erosion rates are faster than human-impacted rates of sediment yield [1]. One explanation for relatively low recent continental sediment yields is that the eroded sediment may be accumulating and stored for an uncertain duration in swelling floodplains and deltas. We present a global compilation of Holocene floodplain accumulation rates. Rates measured over the last ~100 years are faster than those averaged over ~1000 years, which in turn are faster than those for the last ~10000 years. Floodplain sediment accumulation measurements, however, are taken at discreet cores or bank exposures, and this introduces both temporal and spatial bias. Vertical accumulation rates are calculated by dividing thickness of sediment by the time-span of accumulation for discrete packages of sediment. Thus, time integrates from the present to a past datum provided by 14C measurements for buried organics (or other chronological tools). We argue that the pattern of rate increase in sedimentation over time is related to infilling behavior of all floodplains and not specifically tied to the supply of (anthropogenic) sediment. The apparent acceleration in sedimentation rates appears globally synchronous over 8000-year timescales, despite diachronous human and land use histories. Moreover, some rate acceleration pre-dates significant human land use. When the effect/bias of averaging time is accounted for, recent accumulation

  19. Flowering time and seed dormancy control use external coincidence to generate life history strategy

    PubMed Central

    Springthorpe, Vicki; Penfield, Steven

    2015-01-01

    Climate change is accelerating plant developmental transitions coordinated with the seasons in temperate environments. To understand the importance of these timing advances for a stable life history strategy, we constructed a full life cycle model of Arabidopsis thaliana. Modelling and field data reveal that a cryptic function of flowering time control is to limit seed set of winter annuals to an ambient temperature window which coincides with a temperature-sensitive switch in seed dormancy state. This coincidence is predicted to be conserved independent of climate at the expense of flowering date, suggesting that temperature control of flowering time has evolved to constrain seed set environment and therefore frequency of dormant and non-dormant seed states. We show that late flowering can disrupt this bet-hedging germination strategy. Our analysis shows that life history modelling can reveal hidden fitness constraints and identify non-obvious selection pressures as emergent features. DOI: http://dx.doi.org/10.7554/eLife.05557.001 PMID:25824056

  20. Galileon gravity and its relevance to late time cosmic acceleration

    SciTech Connect

    Gannouji, Radouane; Sami, M.

    2010-07-15

    We consider the covariant Galileon gravity taking into account the third order and fourth order scalar field Lagrangians L{sub 3}({pi}) and L{sub 4}({pi}), consisting of three and four {pi}'s with four and five derivatives acting on them, respectively. The background dynamical equations are set up for the system under consideration and the stability of the self-accelerating solution is demonstrated in a general setting. We extended this study to the general case of the fifth order theory. For the spherically symmetric static background, we spell out conditions for the suppression of fifth force effects mediated by the Galileon field {pi}. We study field perturbations in the fixed background and investigate the conditions for their causal propagation. We also briefly discuss metric fluctuations and derive an evolution equation for matter perturbations in Galileon gravity.

  1. Bunching in time at the ATLAS (Argonne Tandem-Linac Accelerator System) accelerator

    SciTech Connect

    Pardo, R.

    1986-01-01

    The ability to manipulate the energy spread and time width of the beam from the ATLAS linac is an important feature used by the experimental program at Argonne. The time resolution which can be obtained on target has been shown to be less than 150 ps. for all beams through /sup 58/Ni. The fundamental ideas which apply to the bunching of heavy ion beams are described and the limitations and capabilities of the bunching system are discussed. A sequential guide for obtaining good timing on target is included.

  2. Subjective Acceleration of Time Experience in Everyday Life across Adulthood

    ERIC Educational Resources Information Center

    John, Dennis; Lang, Frieder R.

    2015-01-01

    Most people believe that time seems to pass more quickly as they age. Building on assumptions of socioemotional selectivity theory, we investigated whether awareness that one's future lifetime is limited is associated with one's experience of time during everyday activities across adulthood in 3 studies. In the first 2 studies (Study 1: N = 608;…

  3. Time-dependent shock acceleration of particles. Effect of the time-dependent injection, with application to supernova remnants

    NASA Astrophysics Data System (ADS)

    Petruk, O.; Kopytko, B.

    2016-11-01

    Three approaches are considered to solve the equation which describes the time-dependent diffusive shock acceleration of test particles at the non-relativistic shocks. At first, the solution of Drury for the particle distribution function at the shock is generalized to any relation between the acceleration time-scales upstream and downstream and for the time-dependent injection efficiency. Three alternative solutions for the spatial dependence of the distribution function are derived. Then, the two other approaches to solve the time-dependent equation are presented, one of which does not require the Laplace transform. At the end, our more general solution is discussed, with a particular attention to the time-dependent injection in supernova remnants. It is shown that, comparing to the case with the dominant upstream acceleration time-scale, the maximum momentum of accelerated particles shifts towards the smaller momenta with increase of the downstream acceleration time-scale. The time-dependent injection affects the shape of the particle spectrum. In particular, (i) the power-law index is not solely determined by the shock compression, in contrast to the stationary solution; (ii) the larger the injection efficiency during the first decades after the supernova explosion, the harder the particle spectrum around the high-energy cutoff at the later times. This is important, in particular, for interpretation of the radio and gamma-ray observations of supernova remnants, as demonstrated on a number of examples.

  4. Time Acceleration Methods for Advection on the Cubed Sphere

    SciTech Connect

    Archibald, Richard K; Evans, Katherine J; White III, James B; Drake, John B

    2009-01-01

    Climate simulation will not grow to the ultrascale without new algorithms to overcome the scalability barriers blocking existing implementations. Until recently, climate simulations concentrated on the question of whether the climate is changing. The emphasis is now shifting to impact assessments, mitigation and adaptation strategies, and regional details. Such studies will require significant increases in spatial resolution and model complexity while maintaining adequate throughput. The barrier to progress is the resulting decrease in time step without increasing single-thread performance. In this paper we demonstrate how to overcome this time barrier for the first standard test defined for the shallow-water equations on a sphere. This paper explains how combining a multiwavelet discontinuous Galerkin method with exact linear part time-evolution schemes can overcome the time barrier for advection equations on a sphere. The discontinuous Galerkin method is a high-order method that is conservative, flexible, and scalable. The addition of multiwavelets to discontinuous Galerkin provides a hierarchical scale structure that can be exploited to improve computational efficiency in both the spatial and temporal dimensions. Exact linear part time-evolution schemes are explicit schemes that remain stable for implicit-size time steps.

  5. GPU acceleration of time-domain fluorescence lifetime imaging

    NASA Astrophysics Data System (ADS)

    Wu, Gang; Nowotny, Thomas; Chen, Yu; Li, David Day-Uei

    2016-01-01

    Fluorescence lifetime imaging microscopy (FLIM) plays a significant role in biological sciences, chemistry, and medical research. We propose a graphic processing unit (GPU) based FLIM analysis tool suitable for high-speed, flexible time-domain FLIM applications. With a large number of parallel processors, GPUs can significantly speed up lifetime calculations compared to CPU-OpenMP (parallel computing with multiple CPU cores) based analysis. We demonstrate how to implement and optimize FLIM algorithms on GPUs for both iterative and noniterative FLIM analysis algorithms. The implemented algorithms have been tested on both synthesized and experimental FLIM data. The results show that at the same precision, the GPU analysis can be up to 24-fold faster than its CPU-OpenMP counterpart. This means that even for high-precision but time-consuming iterative FLIM algorithms, GPUs enable fast or even real-time analysis.

  6. Return to Old Times: Rural Romanticism in American Education History.

    ERIC Educational Resources Information Center

    Warren, Donald

    1984-01-01

    Discusses the rural-urban dichotomy that regularly surfaces in educational history and argues that a full understanding of the role of cities is needed to overcome a rural romanticism that ill-serves public education policy. (CMG)

  7. Time-accurate Navier-Stokes calculations with multigrid acceleration

    NASA Technical Reports Server (NTRS)

    Melson, N. D.; Sanetrik, Mark D.; Atkins, Harold L.

    1993-01-01

    An efficient method for calculating unsteady flows is presented, with emphasis on a modified version of the thin-layer Navier-Stokes equations. Fourier stability analysis is used to illustrate the effect of treating the source term implicitly instead of explicity, as well as to illustrate other algorithmic choices. A 2D circular cylinder (with a Reynolds number of 1200 and a Mach number of 0.3) is calculated. The present scheme requires only about 10 percent of the computer time required by global minimum time stepping.

  8. Time dependent solution for acceleration of tau-leaping

    NASA Astrophysics Data System (ADS)

    Fu, Jin; Wu, Sheng; Petzold, Linda R.

    2013-02-01

    The tau-leaping method is often effective for speeding up discrete stochastic simulation of chemically reacting systems. However, when fast reactions are involved, the speed-up for this method can be quite limited. One way to address this is to apply a stochastic quasi-steady state assumption. However we must be careful when using this assumption. If the fast subsystem cannot reach a steady distribution fast enough, the quasi-steady-state assumption will propagate error into the simulation. To avoid these errors, we propose to use the time dependent solution rather than the quasi-steady-state. Generally speaking, the time dependent solution is not easy to derive for an arbitrary network. However, for some common motifs we do have time dependent solutions. We derive the time dependent solutions for these motifs, and then show how they can be used with tau-leaping to achieve substantial speed-ups, including for a realistic model of blood coagulation. Although the method is complicated, we have automated it.

  9. Time dependent solution for acceleration of tau-leaping

    SciTech Connect

    Fu, Jin; Wu, Sheng; Petzold, Linda R.

    2013-02-15

    The tau-leaping method is often effective for speeding up discrete stochastic simulation of chemically reacting systems. However, when fast reactions are involved, the speed-up for this method can be quite limited. One way to address this is to apply a stochastic quasi-steady state assumption. However we must be careful when using this assumption. If the fast subsystem cannot reach a steady distribution fast enough, the quasi-steady-state assumption will propagate error into the simulation. To avoid these errors, we propose to use the time dependent solution rather than the quasi-steady-state. Generally speaking, the time dependent solution is not easy to derive for an arbitrary network. However, for some common motifs we do have time dependent solutions. We derive the time dependent solutions for these motifs, and then show how they can be used with tau-leaping to achieve substantial speed-ups, including for a realistic model of blood coagulation. Although the method is complicated, we have automated it.

  10. Acceleration in a nonplanar time-dependent billiard

    NASA Astrophysics Data System (ADS)

    Raeisi, Sedighe; Eslami, Parvin

    2016-08-01

    We study the dynamical properties of a particle in a nonplanar square billiard. The plane of the billiard has a sinusoidal shape. We consider both the static and time-dependent plane. We study the affect of different parameters that control the geometry of the billiard in this model. We consider variations of different parameters of the model and describe how the particle trajectory is affected by these parameters. We also investigate the dynamical behavior of the system in the static condition using its reduced phase plot and show that the dynamics of the particle inside the billiard may be regular, mixed, or chaotic. Finally, the problem of the particle energy growth is studied in the billiard with the time-dependent plane. We show that when in the static case, the billiard is chaotic, then the particle energy in the time-dependent billiard grows for a small number of collisions, and then it starts to saturate. But when the dynamics of the static case is regular, then the particle average energy in the time-dependent situation stays constant.

  11. Acceleration in a nonplanar time-dependent billiard.

    PubMed

    Raeisi, Sedighe; Eslami, Parvin

    2016-08-01

    We study the dynamical properties of a particle in a nonplanar square billiard. The plane of the billiard has a sinusoidal shape. We consider both the static and time-dependent plane. We study the affect of different parameters that control the geometry of the billiard in this model. We consider variations of different parameters of the model and describe how the particle trajectory is affected by these parameters. We also investigate the dynamical behavior of the system in the static condition using its reduced phase plot and show that the dynamics of the particle inside the billiard may be regular, mixed, or chaotic. Finally, the problem of the particle energy growth is studied in the billiard with the time-dependent plane. We show that when in the static case, the billiard is chaotic, then the particle energy in the time-dependent billiard grows for a small number of collisions, and then it starts to saturate. But when the dynamics of the static case is regular, then the particle average energy in the time-dependent situation stays constant. PMID:27627308

  12. A History of Spike-Timing-Dependent Plasticity

    PubMed Central

    Markram, Henry; Gerstner, Wulfram; Sjöström, Per Jesper

    2011-01-01

    How learning and memory is achieved in the brain is a central question in neuroscience. Key to today’s research into information storage in the brain is the concept of synaptic plasticity, a notion that has been heavily influenced by Hebb's (1949) postulate. Hebb conjectured that repeatedly and persistently co-active cells should increase connective strength among populations of interconnected neurons as a means of storing a memory trace, also known as an engram. Hebb certainly was not the first to make such a conjecture, as we show in this history. Nevertheless, literally thousands of studies into the classical frequency-dependent paradigm of cellular learning rules were directly inspired by the Hebbian postulate. But in more recent years, a novel concept in cellular learning has emerged, where temporal order instead of frequency is emphasized. This new learning paradigm – known as spike-timing-dependent plasticity (STDP) – has rapidly gained tremendous interest, perhaps because of its combination of elegant simplicity, biological plausibility, and computational power. But what are the roots of today’s STDP concept? Here, we discuss several centuries of diverse thinking, beginning with philosophers such as Aristotle, Locke, and Ribot, traversing, e.g., Lugaro’s plasticità and Rosenblatt’s perceptron, and culminating with the discovery of STDP. We highlight interactions between theoretical and experimental fields, showing how discoveries sometimes occurred in parallel, seemingly without much knowledge of the other field, and sometimes via concrete back-and-forth communication. We point out where the future directions may lie, which includes interneuron STDP, the functional impact of STDP, its mechanisms and its neuromodulatory regulation, and the linking of STDP to the developmental formation and continuous plasticity of neuronal networks. PMID:22007168

  13. Accelerating Real-Time String Searching with Multicore Processors

    SciTech Connect

    Villa, Oreste; Scarpazza, Daniele P.; Petrini, Fabrizio

    2008-04-01

    String searching is at the core of tools used to search, filter, and protect data, but this has become increasingly difficult to do in real time as communication speed grows. The authors present an optimization strategy for a popular algorithm that fully exploits the IBM Cell Broadband Engine architecture to perform exact string matching against large dictionaries and also offer various solutions to alleviate memory congestion.

  14. Wormholes record species history in space and time

    PubMed Central

    Hedges, S. Blair

    2013-01-01

    Genetic and fossil data often lack the spatial and temporal precision for tracing the recent biogeographic history of species. Data with finer resolution are needed for studying distributional changes during modern human history. Here, I show that printed wormholes in rare books and artwork are trace fossils of wood-boring species with unusually accurate locations and dates. Analyses of wormholes printed in western Europe since the fifteenth century document the detailed biogeographic history of two putative species of invasive wood-boring beetles. Their distributions now overlap broadly, as an outcome of twentieth century globalization. However, the wormhole record revealed, unexpectedly, that their original ranges were contiguous and formed a stable line across central Europe, apparently a result of competition. Extension of the wormhole record, globally, will probably reveal other species and evolutionary insights. These data also provide evidence for historians in determining the place of origin or movement of a woodblock, book, document or art print. PMID:23173192

  15. Wormholes record species history in space and time.

    PubMed

    Hedges, S Blair

    2013-02-23

    Genetic and fossil data often lack the spatial and temporal precision for tracing the recent biogeographic history of species. Data with finer resolution are needed for studying distributional changes during modern human history. Here, I show that printed wormholes in rare books and artwork are trace fossils of wood-boring species with unusually accurate locations and dates. Analyses of wormholes printed in western Europe since the fifteenth century document the detailed biogeographic history of two putative species of invasive wood-boring beetles. Their distributions now overlap broadly, as an outcome of twentieth century globalization. However, the wormhole record revealed, unexpectedly, that their original ranges were contiguous and formed a stable line across central Europe, apparently a result of competition. Extension of the wormhole record, globally, will probably reveal other species and evolutionary insights. These data also provide evidence for historians in determining the place of origin or movement of a woodblock, book, document or art print.

  16. Characteristics of Four SPE Classes According to Onset Timing and Proton Acceleration Patterns

    NASA Astrophysics Data System (ADS)

    Kim, Roksoon

    2015-04-01

    In our previous work (Kim et al., 2015), we suggested a new classification scheme, which categorizes the SPEs into four groups based on association with flare or CME inferred from onset timings as well as proton acceleration patterns using multienergy observations. In this study, we have tried to find whether there are any typical characteristics of associated events and acceleration sites in each group using 42 SPEs from 1997 to 2012. We find: (i) if the proton acceleration starts from a lower energy, a SPE has a higher chance to be a strong event (> 5000 pfu) even if the associated flare and CME are not so strong. The only difference between the SPEs associated with flare and CME is the location of the acceleration site. For the former, the sites are very low ( ~1 Rs) and close to the western limb, while the latter has a relatively higher (mean=6.05 Rs) and wider acceleration sites. (ii) When the proton acceleration starts from the higher energy, a SPE tends to be a relatively weak event (< 1000 pfu), in spite of its associated CME is relatively stronger than previous group. (iii) The SPEs categorized by the simultaneous proton acceleration in whole energy range within 10 minutes, tend to show the weakest proton flux (mean=327 pfu) in spite of strong related eruptions. Their acceleration heights are very close to the locations of type II radio bursts. Based on those results, we suggest that the different characteristics of the four groups are mainly due to the different mechanisms governing the acceleration pattern and interval, and different condition such as the acceleration location.

  17. A history of phenotypic plasticity accelerates adaptation to a new environment.

    PubMed

    Fierst, J L

    2011-09-01

    Can a history of phenotypic plasticity increase the rate of adaptation to a new environment? Theory suggests it can be through two different mechanisms. Phenotypically plastic organisms can adapt rapidly to new environments through genetic assimilation, or the fluctuating environments that result in phenotypic plasticity can produce evolvable genetic architectures. In this article, I studied a model of a gene regulatory network that determined a phenotypic character in one population selected for phenotypic plasticity and a second population in a constant environment. A history of phenotypic plasticity increased the rate of adaptation in a new environment, but the amount of this increase was dependent on the strength of selection in the original environment. Phenotypic variance in the original environment predicted the adaptive capacity of the trait within, but not between, plastic and nonplastic populations. These results have implications for invasive species and ecological studies of rapid adaptation.

  18. Accelerated metabolic susceptibility to type 2 diabetes in older women with a history of gestational diabetes.

    PubMed

    Ryan, Alice S; McLenithan, John C; Zietowski, Gretchen M

    2013-06-01

    The purpose of this study is to compare central obesity, insulin sensitivity, and cardiovascular disease risk factors between premenopausal and postmenopausal women with a history of gestational diabetes mellitus (GDM), controls, and women with type 2 diabetes (T2DM). Subjects were 73 overweight/obese and sedentary women who had a history of GDM (n=31) and were either premenopausal (n=11, 44±1 years, X±s.e.m.), postmenopausal (n=20, 58±1 years), or without a history of GDM as healthy postmenopausal controls (n=27, 57±1 years) or postmenopausal with T2DM (n=16, 59±1 years). The premenopausal GDM women had higher maximal oxygen uptake and lower visceral fat than the other three groups (P<0.05). BMI, %body fat, subcutaneous abdominal fat, and intramuscular fat did not differ significantly among the four groups. Glucose utilization (M, 3 h 40 mU/m(2) per min hyperinsulinemic-euglycemic clamps) was 27% higher (P=0.05) in pre- than postmenopausal GDM and was not different between premenopausal GDM and postmenopausal controls. M was 28% lower (P=0.06) in postmenopausal GDM than controls and was not significantly different between postmenopausal GDM and T2DM groups. Thus, despite being younger and more physically fit, premenopausal women with prior GDM display similar central obesity, glucose, and metabolic profiles as postmenopausal controls. Postmenopausal women with prior GDM are more insulin resistant than controls of similar age, adiposity, and fitness levels and display comparable glucose utilization rates as similar as women with T2DM suggesting that a prior history of GDM may be an early manifestation of increased risk of later T2DM. PMID:23781323

  19. Regional-specific Stochastic Simulation of Spatially-distributed Ground-motion Time Histories using Wavelet Packet Analysis

    NASA Astrophysics Data System (ADS)

    Huang, D.; Wang, G.

    2014-12-01

    Stochastic simulation of spatially distributed ground-motion time histories is important for performance-based earthquake design of geographically distributed systems. In this study, we develop a novel technique to stochastically simulate regionalized ground-motion time histories using wavelet packet analysis. First, a transient acceleration time history is characterized by wavelet-packet parameters proposed by Yamamoto and Baker (2013). The wavelet-packet parameters fully characterize ground-motion time histories in terms of energy content, time- frequency-domain characteristics and time-frequency nonstationarity. This study further investigates the spatial cross-correlations of wavelet-packet parameters based on geostatistical analysis of 1500 regionalized ground motion data from eight well-recorded earthquakes in California, Mexico, Japan and Taiwan. The linear model of coregionalization (LMC) is used to develop a permissible spatial cross-correlation model for each parameter group. The geostatistical analysis of ground-motion data from different regions reveals significant dependence of the LMC structure on regional site conditions, which can be characterized by the correlation range of Vs30 in each region. In general, the spatial correlation and cross-correlation of wavelet-packet parameters are stronger if the site condition is more homogeneous. Using the regional-specific spatial cross-correlation model and cokriging technique, wavelet packet parameters at unmeasured locations can be best estimated, and regionalized ground-motion time histories can be synthesized. Case studies and blind tests demonstrated that the simulated ground motions generally agree well with the actual recorded data, if the influence of regional-site conditions is considered. The developed method has great potential to be used in computational-based seismic analysis and loss estimation in a regional scale.

  20. Evaluation of highly accelerated real-time cardiac cine MRI in tachycardia.

    PubMed

    Bassett, Elwin C; Kholmovski, Eugene G; Wilson, Brent D; DiBella, Edward V R; Dosdall, Derek J; Ranjan, Ravi; McGann, Christopher J; Kim, Daniel

    2014-02-01

    Electrocardiogram (ECG)-gated breath-hold cine MRI is considered to be the gold standard test for the assessment of cardiac function. However, it may fail in patients with arrhythmia, impaired breath-hold capacity and poor ECG gating. Although ungated real-time cine MRI may mitigate these problems, commercially available real-time cine MRI pulse sequences using parallel imaging typically yield relatively poor spatiotemporal resolution because of their low image acquisition efficiency. As an extension of our previous work, the purpose of this study was to evaluate the diagnostic quality and accuracy of eight-fold-accelerated real-time cine MRI with compressed sensing (CS) for the quantification of cardiac function in tachycardia, where it is challenging for real-time cine MRI to provide sufficient spatiotemporal resolution. We evaluated the performances of eight-fold-accelerated cine MRI with CS, three-fold-accelerated real-time cine MRI with temporal generalized autocalibrating partially parallel acquisitions (TGRAPPA) and ECG-gated breath-hold cine MRI in 21 large animals with tachycardia (mean heart rate, 104 beats per minute) at 3T. For each cine MRI method, two expert readers evaluated the diagnostic quality in four categories (image quality, temporal fidelity of wall motion, artifacts and apparent noise) using a Likert scale (1-5, worst to best). One reader evaluated the left ventricular functional parameters. The diagnostic quality scores were significantly different between the three cine pulse sequences, except for the artifact level between CS and TGRAPPA real-time cine MRI. Both ECG-gated breath-hold cine MRI and eight-fold accelerated real-time cine MRI yielded all four scores of ≥ 3.0 (acceptable), whereas three-fold-accelerated real-time cine MRI yielded all scores below 3.0, except for artifact (3.0). The left ventricular ejection fraction (LVEF) measurements agreed better between ECG-gated cine MRI and eight-fold-accelerated real-time cine MRI

  1. Pushover, Response Spectrum and Time History Analyses of Safe Rooms in a Poor Performance Masonry Building

    SciTech Connect

    Mazloom, M.

    2008-07-08

    The idea of safe room has been developed for decreasing the earthquake casualties in masonry buildings. The information obtained from the previous ground motions occurring in seismic zones expresses the lack of enough safety of these buildings against earthquakes. For this reason, an attempt has been made to create some safe areas inside the existing masonry buildings, which are called safe rooms. The practical method for making these safe areas is to install some prefabricated steel frames in some parts of the existing structure. These frames do not carry any service loads before an earthquake. However, if a devastating earthquake happens and the load bearing walls of the building are destroyed, some parts of the floors, which are in the safe areas, will fall on the roof of the installed frames and the occupants who have sheltered there will survive. This paper presents the performance of these frames located in a destroying three storey masonry building with favorable conclusions. In fact, the experimental pushover diagram of the safe room located at the ground-floor level of this building is compared with the analytical results and it is concluded that pushover analysis is a good method for seismic performance evaluation of safe rooms. For time history analysis the 1940 El Centro, the 2003 Bam, and the 1990 Manjil earthquake records with the maximum peak accelerations of 0.35g were utilized. Also the design spectrum of Iranian Standard No. 2800-05 for the ground kind 2 is used for response spectrum analysis. The results of time history, response spectrum and pushover analyses show that the strength and displacement capacity of the steel frames are adequate to accommodate the distortions generated by seismic loads and aftershocks properly.

  2. On Spin-Statistics and Bogoliubov Transformations in Flat Space-Time with Acceleration Conditions

    NASA Astrophysics Data System (ADS)

    Good, Michael R. R.

    2013-01-01

    A single real scalar field of spin zero obeying the Klein-Gordon equation in flat space-time under external conditions is considered in the context of the spin-statistics connection. An imposed accelerated boundary on the field is made to become, in the far future, (1) asymptotically inertial and (2) asymptotically noninertial (with an infinite acceleration). The constant acceleration Unruh effect is also considered. The systems involving nontrivial Bogoliubov transformations contain dynamics which point to commutation relations. Particles described by in-modes obey the same statistics as particles described by out-modes. It is found in the nontrivial systems that the spin-statistics connection can be manifest from the acceleration. The equation of motion for the boundary which forever emits thermal radiation is revealed.

  3. HEART Pathway Accelerated Diagnostic Protocol Implementation: Prospective Pre-Post Interrupted Time Series Design and Methods

    PubMed Central

    Wells, Brian J

    2016-01-01

    Background Most patients presenting to US Emergency Departments (ED) with chest pain are hospitalized for comprehensive testing. These evaluations cost the US health system >$10 billion annually, but have a diagnostic yield for acute coronary syndrome (ACS) of <10%. The history/ECG/age/risk factors/troponin (HEART) Pathway is an accelerated diagnostic protocol (ADP), designed to improve care for patients with acute chest pain by identifying patients for early ED discharge. Prior efficacy studies demonstrate that the HEART Pathway safely reduces cardiac testing, while maintaining an acceptably low adverse event rate. Objective The purpose of this study is to determine the effectiveness of HEART Pathway ADP implementation within a health system. Methods This controlled before-after study will accrue adult patients with acute chest pain, but without ST-segment elevation myocardial infarction on electrocardiogram for two years and is expected to include approximately 10,000 patients. Outcomes measures include hospitalization rate, objective cardiac testing rates (stress testing and angiography), length of stay, and rates of recurrent cardiac care for participants. Results In pilot data, the HEART Pathway decreased hospitalizations by 21%, decreased hospital length (median of 12 hour reduction), without increasing adverse events or recurrent care. At the writing of this paper, data has been collected on >5000 patient encounters. The HEART Pathway has been fully integrated into health system electronic medical records, providing real-time decision support to our providers. Conclusions We hypothesize that the HEART Pathway will safely reduce healthcare utilization. This study could provide a model for delivering high-value care to the 8-10 million US ED patients with acute chest pain each year. ClinicalTrial Clinicaltrials.gov NCT02056964; https://clinicaltrials.gov/ct2/show/NCT02056964 (Archived by WebCite at http://www.webcitation.org/6ccajsgyu) PMID:26800789

  4. Highly accelerated real-time cardiac cine MRI using k-t SPARSE-SENSE.

    PubMed

    Feng, Li; Srichai, Monvadi B; Lim, Ruth P; Harrison, Alexis; King, Wilson; Adluru, Ganesh; Dibella, Edward V R; Sodickson, Daniel K; Otazo, Ricardo; Kim, Daniel

    2013-07-01

    For patients with impaired breath-hold capacity and/or arrhythmias, real-time cine MRI may be more clinically useful than breath-hold cine MRI. However, commercially available real-time cine MRI methods using parallel imaging typically yield relatively poor spatio-temporal resolution due to their low image acquisition speed. We sought to achieve relatively high spatial resolution (∼2.5 × 2.5 mm(2)) and temporal resolution (∼40 ms), to produce high-quality real-time cine MR images that could be applied clinically for wall motion assessment and measurement of left ventricular function. In this work, we present an eightfold accelerated real-time cardiac cine MRI pulse sequence using a combination of compressed sensing and parallel imaging (k-t SPARSE-SENSE). Compared with reference, breath-hold cine MRI, our eightfold accelerated real-time cine MRI produced significantly worse qualitative grades (1-5 scale), but its image quality and temporal fidelity scores were above 3.0 (adequate) and artifacts and noise scores were below 3.0 (moderate), suggesting that acceptable diagnostic image quality can be achieved. Additionally, both eightfold accelerated real-time cine and breath-hold cine MRI yielded comparable left ventricular function measurements, with coefficient of variation <10% for left ventricular volumes. Our proposed eightfold accelerated real-time cine MRI with k-t SPARSE-SENSE is a promising modality for rapid imaging of myocardial function.

  5. Mini acceleration and deceleration driving strategy to increase the operational time of flywheel hybrid module

    NASA Astrophysics Data System (ADS)

    Manaf, Muhammad Zaidan Abdul; Fakeruddin, Shafarul Hafidi; Zakaria, Mohamad Shukri; Saadun, Mohd Noor Asril; Hanafi, Mohd Hafidzal Mohd

    2015-05-01

    This paper presents a new driving strategy to increase the operational time of flywheel hybrid module. The flywheel hybrid module contains low cost mechanical parts which installed on the small motorcycle. Based on normal driving cycles characteristics, the Mini-AD driving strategy is develop. It is involved a series of short or mini acceleration cycle and short deceleration cycle on top of the normal driving cycles. The new strategy is simulated for flywheel hybrid module, aimed for acceleration phase only. Simulations show that the new driving strategy can increase the operational time of flywheel hybrid module up to 62.5%.

  6. Factors affecting the coefficient of variation of stride time of the elderly without falling history: a prospective study.

    PubMed

    Matsuda, Kensuke; Ikeda, Shou; Nakahara, Masami; Ikeda, Takuro; Okamoto, Ryuji; Kurosawa, Kazuo; Horikawa, Etuo

    2015-04-01

    [Purpose] The purpose of this study was to investigate the factors affecting the coefficient of variation (CV) of stride time in an exercise intervention for the elderly without falling history. [Subjects and Methods] The subjects were 42 elderly women who had participated in a care prevention program for 12 weeks. Stride time CV, motor function, movement ability, balance, Modified Falls Efficacy Scale (MFES) score, and Life-space Assessment (LSA) score before and after the intervention were examined for significant differences using the paired t-test. Multiple regression analysis was used to determine the factors that changed in the stride time CV. [Results] There were significant differences in muscle strength, sit-and-reach flexibility, the one-leg standing time (eyes open), the maximum walking speed, local stability of trunk acceleration, The Timed Up and Go Test (TUG-T), the MFES score, and the LSA score between the pre-intervention and post-intervention. Stepwise multiple regression analysis revealed that improvement of quadriceps muscle strength, sit-and-reach flexibility, the one-leg standing time, TUG-T, local stability of trunk acceleration (vertical direction) and MFES score were independent variables explaining the reduction in stride time CV. [Conclusion] The results was suggested that it might be possible to reduce the stride time CV by improving strength, flexibility and dynamic balance, and reducing fear of falls through interventions.

  7. Factors affecting the coefficient of variation of stride time of the elderly without falling history: a prospective study

    PubMed Central

    Matsuda, Kensuke; Ikeda, Shou; Nakahara, Masami; Ikeda, Takuro; Okamoto, Ryuji; Kurosawa, Kazuo; Horikawa, Etuo

    2015-01-01

    [Purpose] The purpose of this study was to investigate the factors affecting the coefficient of variation (CV) of stride time in an exercise intervention for the elderly without falling history. [Subjects and Methods] The subjects were 42 elderly women who had participated in a care prevention program for 12 weeks. Stride time CV, motor function, movement ability, balance, Modified Falls Efficacy Scale (MFES) score, and Life-space Assessment (LSA) score before and after the intervention were examined for significant differences using the paired t-test. Multiple regression analysis was used to determine the factors that changed in the stride time CV. [Results] There were significant differences in muscle strength, sit-and-reach flexibility, the one-leg standing time (eyes open), the maximum walking speed, local stability of trunk acceleration, The Timed Up and Go Test (TUG-T), the MFES score, and the LSA score between the pre-intervention and post-intervention. Stepwise multiple regression analysis revealed that improvement of quadriceps muscle strength, sit-and-reach flexibility, the one-leg standing time, TUG-T, local stability of trunk acceleration (vertical direction) and MFES score were independent variables explaining the reduction in stride time CV. [Conclusion] The results was suggested that it might be possible to reduce the stride time CV by improving strength, flexibility and dynamic balance, and reducing fear of falls through interventions. PMID:25995563

  8. Choice reaction time to movement of eccentric visual targets during concurrent rotary acceleration

    NASA Technical Reports Server (NTRS)

    Hamerman, J. A.

    1979-01-01

    This study investigates the influence of concurrent rotary acceleration on choice reaction time (RT) to a small, accelerating visual cursor on a cathode-ray tube. Subjects sat in an enclosed rotating device at the center of rotation and observed a 3-mm dot accelerating at different rates across a cathode-ray tube. The dot was viewed at various eccentricities under conditions of visual stimulation alone and with concurrent rotary acceleration. Subjects responded to both vertical and horizontal dot movements. There was a significant inverse relationship between choice RT and level of dot acceleration (p less than .001), and a significant direct relationship between choice RT and eccentricity (p less than .001). There was no significant difference between choice RT to vertical or horizontal dot motion (p greater than .25), and choice RT was not significantly affected by concurrent rotary acceleration (p greater than .10). The results are discussed in terms of the effects of vestibular stimulation on choice RT to visual motion.

  9. Acceleration of proliferative response of mouse fibroblasts by short-time pretreatment with polyphenols.

    PubMed

    Tsuruya, Makoto; Niwano, Yoshimi; Nakamura, Keisuke; Kanno, Taro; Nakashima, Takuji; Egusa, Hiroshi; Sasaki, Keiichi

    2014-11-01

    Under the hypothesis that photo-irradiated proanthocyanidin could accelerate wound healing through reactive oxygen species (ROS) formation, we examined the effect of proanthocyanidin on 3T3-L1 mouse fibroblasts with or without photo-irradiation. As a result, irrespective of presence or absence of photo-irradiation, only 1 min exposure of the cells to proanthocyanidin resulted in accelerated proliferation of the cells in a concentration-dependent manner. Similarly to proanthocyanidin, 1 min pretreatment with catechin, caffeic acid, and chlorogenic acid accelerated the proliferative response, but gallic acid, epicatechin gallate, epigallocatechin, and epigallocatechin gallate failed. If incorporated active ingredient such as proanthocyanidin for such a short time as 1 min accelerates the proliferation response, a bioassay was conducted by utilizing antioxidant potential of proanthocyanidin. That is, intracellular oxidation of 2',7'-dichlorodihydrofluorescin induced by H2O2 was significantly inhibited when the cells were pretreated with proanthocyanidin for 1 min, suggesting that incorporated proanthocyanidin into the cells exerted antioxidant effect. This was also supported by a liquid chromatography/mass spectrometry analysis in which incorporation of proanthocyanidin components such as catechin monomers and dimers into the cells within 1 min was confirmed. These results suggest that active polyphenolic compounds such as proanthocyanidin, catechin, caffeic acid, and chlorogenic acid incorporated into the cells in such a short time as 1 min could accelerate the proliferative response of the cells. PMID:25173673

  10. The Seismic Reliability of Offshore Structures Based on Nonlinear Time History Analyses

    SciTech Connect

    Hosseini, Mahmood; Karimiyani, Somayyeh; Ghafooripour, Amin; Jabbarzadeh, Mohammad Javad

    2008-07-08

    Regarding the past earthquakes damages to offshore structures, as vital structures in the oil and gas industries, it is important that their seismic design is performed by very high reliability. Accepting the Nonlinear Time History Analyses (NLTHA) as the most reliable seismic analysis method, in this paper an offshore platform of jacket type with the height of 304 feet, having a deck of 96 feet by 94 feet, and weighing 290 million pounds has been studied. At first, some Push-Over Analyses (POA) have been preformed to recognize the more critical members of the jacket, based on the range of their plastic deformations. Then NLTHA have been performed by using the 3-components accelerograms of 100 earthquakes, covering a wide range of frequency content, and normalized to three Peak Ground Acceleration (PGA) levels of 0.3 g, 0.65 g, and 1.0 g. By using the results of NLTHA the damage and rupture probabilities of critical member have been studied to assess the reliability of the jacket structure. Regarding that different structural members of the jacket have different effects on the stability of the platform, an 'importance factor' has been considered for each critical member based on its location and orientation in the structure, and then the reliability of the whole structure has been obtained by combining the reliability of the critical members, each having its specific importance factor.

  11. 3-Component acceleration field measurement by dual-time stereoscopic particle image velocimetry

    NASA Astrophysics Data System (ADS)

    Perret, L.; Braud, P.; Fourment, C.; David, L.; Delville, J.

    2006-05-01

    In this article, a multiplane stereo-particle image velocimetry (PIV) system was implemented and validated to measure the three-component acceleration field in a plane of turbulent flows. The employed technique relies on the use of two stereoscopic particle image velocimetry (SPIV) systems to measure pairs of velocity fields superimposed in space but shifted in time. The time delay between the two velocity fields enables the implementation of a finite difference scheme to compute temporal derivatives. The use of two synchronized SPIV systems allows us to overcome the limited acquisition rate of PIV systems when dealing with highly turbulent flows. Moreover, a methodology based on the analysis of the spectral error distribution is described here to determine the optimal time delay to compute time derivatives. The present dual-time SPIV arrangement and the proposed analysis method are applied to measure three-component acceleration fields in a cross section of a subsonic plane turbulent mixing layer.

  12. Jump Back in Time: A Living History Resource

    ERIC Educational Resources Information Center

    Peterson, Carol

    2004-01-01

    Gather students and jump back in time to experience what life was like "back then." Through this book, during each day of immersion, students rotate through 14-18 stations of math and vocabulary activities, games, crafts, costumes, and food. Explore legends, songs, maps, and historical events along the way to understand specific times and places…

  13. Force-Time Characteristics and Running Velocity of Male Sprinters During the Acceleration Phase of Sprinting.

    ERIC Educational Resources Information Center

    Mero, Antti

    1988-01-01

    Investigation of the force-time characteristics of eight male sprinters during the acceleration phase of the sprint start suggested that the braking and propulsion phases occur immediately after the block phase and that muscle strength strongly affects running velocity in the sprint start. (Author/CB)

  14. The Gift of Time: Today's Academic Acceleration Case Study Voices of Experience

    ERIC Educational Resources Information Center

    Scheibel, Susan Riley

    2010-01-01

    The purpose of this qualitative case study was to examine today's academic acceleration from the lived experience and perspectives of two young adults whose education was shortened, thereby allowing them the gift of time. Through personal interviews, parent interviews, and physical artifacts, the researcher gained a complex, holistic understanding…

  15. Sensitivity Upgrades to the Idaho Accelerator Center Neutron Time of Flight Spectrometer

    SciTech Connect

    Thompson, S. J.; Kinlaw, M. T.; Harmon, J. F.; Wells, D. P.; Hunt, A. W.

    2007-10-26

    Past experiments have shown that discrimination between between fissionable and non-fissionable materials is possible using an interrogation technique that monitors for high energy prompt fission neutrons. Several recent upgrades have been made to the neutron time of flight spectrometer at the Idaho Accelerator Center with the intent of increasing neutron detection sensitivity, allowing for system use in nonproliferation and security applications.

  16. [The history of medicine in the ancient time].

    PubMed

    Tesarová, Drahomíra

    2012-01-01

    This article deals with the history of medicine in the ancient Greece; from the cult of the God Asklepios, to the founder of the scientific rational medicine, Hippokrates. The humoral theory of Hippokrates is explained (the human body consists from four liquids) and his ideal of a physician's approach to a patient is emphasized. In the Hellenistic period the medical development continued in the Alexandria Medical School (Herofilos and Erasistratos). At first, not much attention was given to medicine and scientific health prevention in ancient Rome. Only 293 AD have physicians from Greece first been invited to Rome--e.g. Asklepiades. During the reign of C. lulius Caesar, foreigners, who engaged in medical practice, were granted Roman citizenship and thanks to a number of benefits the medical condition in Roman Empire blossomed. Medical clinics (iatreia), infirmaries (valetudinaria) and, under the influence of Christianity, hospitals were established. In the 2nd century AD ancient medicine reached its climax with physician Galenos, who created the entire system of medical science and became the most significant, but also last medical figure of ancient Rome.

  17. The PDV Velocity History and Shock Arrival Time Analyzer

    2006-08-29

    This software allows the user to analyze heterodyne beat signals generated when a Doppler-shifted laser light interacts with un-shifted laser light. The software analyzes the data in a joint time frequency domain to extract instantaneous velocity.

  18. Finite-time position and velocity estimation adapted to noisy biased acceleration measurements from periodic motion

    NASA Astrophysics Data System (ADS)

    Estrada, Antonio; Efimov, Denis; Perruquetti, Wilfrid

    2016-09-01

    The present work focuses on the problem of velocity and position estimation. A solution is presented for a class of oscillating systems in which position, velocity and acceleration are zero mean signals. The proposed scheme considers that the dynamic model of the system is unknown. Only noisy acceleration measurements, that may be contaminated by zero mean noise and constant bias, are considered to be available. The proposal uses the periodic nature of the signals obtaining finite-time estimations while tackling integration drift accumulation.

  19. Nursing and en route care: history in time of war.

    PubMed

    Davis, R Scott; Connelly, Linda K

    2011-01-01

    The mission of the en route caregiver is to provide critical care in military helicopters for wounded Warriors. This care minimizes the effects of the wounds and injuries, and improves morbidity and mortality. This article will focus on the history of Army Nursing en route care. From World War II through Vietnam, and continuing through the War on Terrorism in Iraq and Afghanistan, Army nurses served in providing en route care in military airplanes and helicopters for patients being transported to higher echelons of care. From aid stations on the battlefield to forward surgical teams which provide life, limb, and eyesight saving care, to the next higher level of care in combat support hospitals, these missions require specialized nursing skills to safely care for the high acuity patients. Before the en route care concept existed, there was not a program to train nurses in these critical skills. There was also a void of information about patient outcomes associated with the nursing assessment and care provided during helicopter medical evacuation (MEDEVAC) of such unstable patients, and the consequent impact on the patient's condition after transport. The role of critical care nurses has proven to be essential and irreplaceable in providing full-spectrum care to casualties of war, in particular, the postsurgical patients transferred from one surgical facility to another in theatre. However, we have only recently developed the concepts over the required skill set, training, equipment, functionality, evidenced-based care, and sustainability of nursing in the en route care role. Much of the work to quantify and qualify nursing care has been done by individuals and individual units whose lessons-learned have only recently been captured.

  20. Dilaton-derived quintessence scenario leading naturally to the late-time acceleration of the Universe

    NASA Astrophysics Data System (ADS)

    Bean, R.; Magueijo, J.

    2001-09-01

    Quintessence scenarios provide a simple explanation for the observed acceleration of the Universe. Yet, explaining why acceleration did not start a long time ago remains a challenge. The idea that the transition from radiation to matter domination played a dynamical role in triggering acceleration has been put forward in various guises. We propose a simple dilaton-derived quintessence model in which temporary vacuum domination is naturally triggered by the radiation to matter transition. In this model Einstein's gravity is preserved but quintessence couples non-minimally to the cold dark matter, but not to ``visible'' matter. Such couplings have been attributed to the dilaton in the low-energy limit of string theory beyond tree level. We also show how a cosmological constant in the string frame translates into a quintessence-type of potential in the atomic frame.

  1. Impact of Interstellar Vehicle Acceleration and Cruise Velocity on Total Mission Mass and Trip Time

    NASA Technical Reports Server (NTRS)

    Frisbee, Robert H.

    2006-01-01

    Far-term interstellar missions, like their near-term solar system exploration counterparts, seek to minimize overall mission trip time and transportation system mass. Trip time is especially important in interstellar missions because of the enormous distances between stars and the finite limit of the speed of light (c). In this paper, we investigate the impact of vehicle acceleration and maximum or cruise velocity (Vcruise) on the total mission trip time. We also consider the impact that acceleration has on the transportation system mass (M) and power (P) (e.g., acceleration approx. power/mass and mass approx. power), as well as the impact that the cruise velocity has on the vehicle mass (e.g., the total mission change in velocity ((Delta)V) approx. Vcruise). For example, a Matter-Antimatter Annihilation Rocket's wet mass (Mwet) with propellant (Mp) will be a function of the dry mass of the vehicle (Mdry) and (Delta)V through the Rocket Equation. Similarly, a laser-driven LightSail's sail mass and laser power and mass will be a function of acceleration, Vcruise, and power-beaming distance (because of the need to focus the laser beam over interstellar distances).

  2. Plotting a History: Black and Postcolonial Feminisms in "New Times"

    ERIC Educational Resources Information Center

    Mirza, Heidi Safia

    2009-01-01

    Black feminist thought is grounded in an understanding of the nature of power and the way black/othered difference women's is systematically organised through social relations. Postcolonial feminist approaches enable us to situate the silent "spectral" power of colonial times as it appears in the production and reproduction of marginalised,…

  3. The history of migraine from Mesopotamian to Medieval times.

    PubMed

    Rose, F C

    1995-10-01

    The first descriptions of migraine can be traced back nearly 4,000 years from the ancient civilizations of Mesopotamia (Sumeria and Babylonia) through Egyptian, Greek and Roman epochs. Through Byzantine, Arabic and Medieval times there are only patchy references until the 17th century, when European physicians first gave full case reports. PMID:8749238

  4. UC Berkeley Seismic Guidelines, Appendix II: Ground Motion Time Histories for the UC Berkeley Campus

    SciTech Connect

    Authors, Various

    2003-06-03

    Three sets of ten time histories each were developed to represent the ground motions for each of the three return periods. All of the time histories are provided as pairs of fault-normal and fault-parallel components. The ground motion time histories are provided in two forms: unmodified, and spectrally modified to match the probabilistic response spectra. The unmodified time histories can be scaled to match the probabilistic response spectra at a specified period, such as the first mode period of the structure being analyzed, while leaving the shape of the response spectrum unmodified. This approach preserves the particular characteristics of the individual time history, together with the peaks and troughs of its response spectrum. These individual characteristics are modified in the spectrally matched time histories, resulting in a suite of ten time histories (for a given return period) that all have the same response spectrum for a given component (fault normal or fault parallel) that follows the smooth shape of the probabilistic response spectrum.

  5. UC Berkeley Seismic Guidelines, Appendix II: Ground Motion TimeHistories for the UC Berkeley Campus

    SciTech Connect

    Various

    2003-06-03

    Three sets of ten time histories each were developed to represent the ground motions for each of the three return periods. All of the time histories are provided as pairs of fault-normal and fault-parallel components. The ground motion time histories are provided in two forms: unmodified, and spectrally modified to match the probabilistic response spectra. The unmodified time histories can be scaled to match the probabilistic response spectra at a specified period, such as the first mode period of the structure being analyzed, while leaving the shape of the response spectrum unmodified. This approach preserves the particular characteristics of the individual time history, together with the peaks and troughs of its response spectrum. These individual characteristics are modified in the spectrally matched time histories, resulting in a suite of ten time histories (for a given return period) that all have the same response spectrum for a given component (fault normal or fault parallel) that follows the smooth shape of the probabilistic response spectrum.

  6. Accelerated multiscale space-time finite element simulation and application to high cycle fatigue life prediction

    NASA Astrophysics Data System (ADS)

    Zhang, Rui; Wen, Lihua; Naboulsi, Sam; Eason, Thomas; Vasudevan, Vijay K.; Qian, Dong

    2016-08-01

    A multiscale space-time finite element method based on time-discontinuous Galerkin and enrichment approach is presented in this work with a focus on improving the computational efficiencies for high cycle fatigue simulations. While the robustness of the TDG-based space-time method has been extensively demonstrated, a critical barrier for the extensive application is the large computational cost due to the additional temporal dimension and enrichment that are introduced. The present implementation focuses on two aspects: firstly, a preconditioned iterative solver is developed along with techniques for optimizing the matrix storage and operations. Secondly, parallel algorithms based on multi-core graphics processing unit are established to accelerate the progressive damage model implementation. It is shown that the computing time and memory from the accelerated space-time implementation scale with the number of degree of freedom N through ˜ O(N^{1.6}) and ˜ O(N), respectively. Finally, we demonstrate the accelerated space-time FEM simulation through benchmark problems.

  7. Ventricular assist devices: history, patient selection, and timing of therapy.

    PubMed

    Tang, Daniel G; Oyer, Philip E; Mallidi, Hari R

    2009-06-01

    Timing of therapy and selection of patients in the use of ventricular assist devices (VADs) can be difficult. In general, consideration for VAD implantation is appropriate in patients with endstage heart failure who are failing optimal medical therapy and in whom no alternative traditional surgical treatment options are available. However, identifying when a particular patient has reached this point is not always straightforward. There are a broad range of medical and surgical therapies for patients with overt heart failure, and this armamentarium is constantly expanding. The risks, benefits, and expected outcomes with VAD therapy have also undergone dramatic changes over the last decade. Advances in technology have led to a proliferation of newer generation devices that are smaller, lighter, easier to implant, and more reliable than previous generation devices. This, in turn, has led to a markedly improved risk-benefit ratio, with increased durability and reduced morbidity. The indications for the implantation of ventricular assist devices have also evolved over the last several years, and specific patient presentations and goals of therapy have led to specific indications. Device therapy has traditionally been classified as bridge to recovery, bridge to transplantation, and destination therapy. However, such designations may not be well defined at the time of implantation, and recovery and response following initiation of VAD support may allow patients to change from one classification to another. The current data regarding indications and timing of device implantation are reviewed. PMID:20559983

  8. The Treatment of Geological Time & the History of Life on Earth in High School Biology Textbooks

    ERIC Educational Resources Information Center

    Summers, Gerald; Decker, Todd; Barrow, Lloyd

    2007-01-01

    In spite of the importance of geological time in evolutionary biology, misconceptions about historical events in the history of life on Earth are common. Glenn (1990) has documented a decline from 1960 to 1989 in the amount of space devoted to the history of life in high school earth science textbooks, but we are aware of no similar study in…

  9. Wound bed preparation and a brief history of TIME.

    PubMed

    Schultz, Gregory S; Barillo, David J; Mozingo, David W; Chin, Gloria A

    2004-04-01

    Management of chronic wounds has progressed from merely assessing the status of a wound to understanding the underlying molecular and cellular abnormalities that prevent the wound from healing. The concept of wound bed preparation has simultaneously evolved to provide a systematic approach to removing these barriers to natural healing and enhancing the effects of advanced therapies. This brief review of wound bed preparation traces the development of these concepts and explains how to apply systematic wound management using the TIME acronym - tissue (non viable or deficient), infection/inflammation, moisture (imbalance) and edge (non advancing or undermined).

  10. Improving linear accelerator service response with a real- time electronic event reporting system.

    PubMed

    Hoisak, Jeremy D P; Pawlicki, Todd; Kim, Gwe-Ya; Fletcher, Richard; Moore, Kevin L

    2014-09-08

    To track linear accelerator performance issues, an online event recording system was developed in-house for use by therapists and physicists to log the details of technical problems arising on our institution's four linear accelerators. In use since October 2010, the system was designed so that all clinical physicists would receive email notification when an event was logged. Starting in October 2012, we initiated a pilot project in collaboration with our linear accelerator vendor to explore a new model of service and support, in which event notifications were also sent electronically directly to dedicated engineers at the vendor's technical help desk, who then initiated a response to technical issues. Previously, technical issues were reported by telephone to the vendor's call center, which then disseminated information and coordinated a response with the Technical Support help desk and local service engineers. The purpose of this work was to investigate the improvements to clinical operations resulting from this new service model. The new and old service models were quantitatively compared by reviewing event logs and the oncology information system database in the nine months prior to and after initiation of the project. Here, we focus on events that resulted in an inoperative linear accelerator ("down" machine). Machine downtime, vendor response time, treatment cancellations, and event resolution were evaluated and compared over two equivalent time periods. In 389 clinical days, there were 119 machine-down events: 59 events before and 60 after introduction of the new model. In the new model, median time to service response decreased from 45 to 8 min, service engineer dispatch time decreased 44%, downtime per event decreased from 45 to 20 min, and treatment cancellations decreased 68%. The decreased vendor response time and reduced number of on-site visits by a service engineer resulted in decreased downtime and decreased patient treatment cancellations.

  11. Improving linear accelerator service response with a real- time electronic event reporting system.

    PubMed

    Hoisak, Jeremy D P; Pawlicki, Todd; Kim, Gwe-Ya; Fletcher, Richard; Moore, Kevin L

    2014-01-01

    To track linear accelerator performance issues, an online event recording system was developed in-house for use by therapists and physicists to log the details of technical problems arising on our institution's four linear accelerators. In use since October 2010, the system was designed so that all clinical physicists would receive email notification when an event was logged. Starting in October 2012, we initiated a pilot project in collaboration with our linear accelerator vendor to explore a new model of service and support, in which event notifications were also sent electronically directly to dedicated engineers at the vendor's technical help desk, who then initiated a response to technical issues. Previously, technical issues were reported by telephone to the vendor's call center, which then disseminated information and coordinated a response with the Technical Support help desk and local service engineers. The purpose of this work was to investigate the improvements to clinical operations resulting from this new service model. The new and old service models were quantitatively compared by reviewing event logs and the oncology information system database in the nine months prior to and after initiation of the project. Here, we focus on events that resulted in an inoperative linear accelerator ("down" machine). Machine downtime, vendor response time, treatment cancellations, and event resolution were evaluated and compared over two equivalent time periods. In 389 clinical days, there were 119 machine-down events: 59 events before and 60 after introduction of the new model. In the new model, median time to service response decreased from 45 to 8 min, service engineer dispatch time decreased 44%, downtime per event decreased from 45 to 20 min, and treatment cancellations decreased 68%. The decreased vendor response time and reduced number of on-site visits by a service engineer resulted in decreased downtime and decreased patient treatment cancellations. PMID

  12. Study of evacuation times based on general accident history

    SciTech Connect

    Mills, G.S.; Neuhauser, K.S.; Smith, J.D.

    1995-12-01

    The RADTRAN 4 computer code, which calculates estimates of accident dose-risk corresponding to specified transportation scenarios, ascribes doses to potentially exposed members of the public. These persons are modeled as not being evacuated from the affected area for 24 hours following a release of radioactive material. Anecdotal evidence has suggested that this value may be unnecessarily conservative; consequently risk estimates are unnecessarily high. An initial survey of recent trucking accidents, reported in newspapers and other periodicals (1988 through 1994), that involved evacuation of the general population in the affected areas was undertaken to establish the actual time required for such evacuations. Accidents involving hazardous materials other than those which are radioactive (e.g., gasoline, insecticides, other chemicals) but also requiring evacuations of nearby residents were included in the survey. However, the resultant set of sufficiently documented trucking incidents yielded rather sparse data [1]. When the probability density distribution of the truck accident data was compared with that resulting from addition of four other (rail and fixed site) incidents, there was no statistically significant difference between them. Therefore, in order to improve the statistical significance of the data set, i.e., maximize the number of pertinent samples, a search for evacuations resulting from all types of accidents was performed. This resulted in many more references; a set of 48 incidents which could be adequately verified was compiled and merged with the original two data sets for a total of 66 evacuation accounts.

  13. Teaching about time by understanding Geologic Time Scales: The Geological Society of America Geologic Time Scale and its history

    NASA Astrophysics Data System (ADS)

    Geissman, J. W.; Walker, J. D.

    2012-12-01

    Geologic time scales, of one form or another, are used in most undergraduate geosciences courses, even including introductory physical geology or equivalent. However, satisfactory discussions of how geologic time scales originated, and how they have evolved to modern versions, are far too often conveniently or inconveniently left out of classroom discussions. Yet it is these kinds of discussions that have the potential of solidifying student appreciation of deep time and rates of geologic processes. We use the history and development of the Geological Society of America Geologic Time Scale, which reflects major developments in the fields of stratigraphy, geochronology, magnetic polarity stratigraphy, astrochronology, and chemostratigraphy, as a focus of how specific details of time scales can be used to teach about time. Advances in all of these fields have allowed many parts of the time scale to be calibrated to precisions approaching less than 0.05 %. Notable time intervals for which collaborative, multifaceted efforts have led to dramatic improvements in our understanding of the character and temporal resolution of key evolutionary events, in both marine and terrestrial environments, include the Triassic-Jurassic, Permo-Triassic, and Neoproterozoic-Phanerozoic boundaries (or transitions). Many of the details, but certainly not all, can be incorporated in discussions of how we know about geologic time in the classroom. For example, we presently understand that both the end-Permian ecological crisis and the biostratigraphic Permian-Triassic boundary, as calibrated by conodonts, lie within a ca. 700 ka long normal polarity chron. The reverse to normal polarity transition at the beginning of this chron is ca. 100 ka earlier than the ecological crisis and thus slightly older than the current estimate, based on high precision U-Pb zircon age determinations, of ca. 252.4 Ma for the Permian-Triassic boundary. This polarity transition occurred during the early part of

  14. A simplified method for calculating temperature time histories in cryogenic wind tunnels

    NASA Technical Reports Server (NTRS)

    Stallings, R. L., Jr.; Lamb, M.

    1976-01-01

    Average temperature time history calculations of the test media and tunnel walls for cryogenic wind tunnels have been developed. Results are in general agreement with limited preliminary experimental measurements obtained in a 13.5-inch pilot cryogenic wind tunnel.

  15. Real-Time and Accelerated Solar Weathering of Commercial PV Modules: Preprint

    SciTech Connect

    Osterwald, C. R.; Pruett, J.; Myers, D. R.; Rummel, S.; Anderberg, A.; Ottoson, L.; Basso, T.

    2001-10-01

    Presented at the 2001 NCPV Program Review Meeting: We report the observed degradation in 6 different types of PV modules as a function of total UV exposure and give a number of recommendations for future weathering tests. Since 1997, using existing ASTM standards for weathering of materials, we have been conducting a solar weathering program on a group of six different types of photovoltaic (PV) modules. The methods used include real-time outdoor, accelerated outdoor, and accelerated indoor weathering. We have employed the technique specified in these standards that quantifies exposure totals by the time integral of the ultraviolet (UV) irradiance. In this paper, we report the observed degradation in the test modules as a function of total UV exposure, and give a number of recommendations for future weathering tests that resulted from our first attempt at a formal test program.

  16. Real-time and accelerated outdoor endurance testing of solar cells

    NASA Technical Reports Server (NTRS)

    Forestieri, A. F.; Anagnostou, E.

    1977-01-01

    Real-time and accelerated outdoor endurance testing was performed on a variety of samples of interest to the National Photovoltaic Conversion Program. The real-time tests were performed at seven different sites and the accelerated tests were performed at one of those sites in the southwestern United States. The purpose of the tests were to help evaluate the lifetime of photovoltaic systems. Three types of samples were tested; transmission samples of possible cover materials, sub-modules constructed using these materials attached to solar cells, and solar cell modules produced by the manufacturers for the ERDA program. Results indicate that suitable cover materials are glass, FEP-A and PFA. Dirt accumulation and cleanability are important factors in the selection of solar cell module covers and encapsulants.

  17. Aircraft model prototypes which have specified handling-quality time histories

    NASA Technical Reports Server (NTRS)

    Johnson, S. H.

    1976-01-01

    Several techniques for obtaining linear constant-coefficient airplane models from specified handling-quality time histories are discussed. One technique, the pseudodata method, solves the basic problem, yields specified eigenvalues, and accommodates state-variable transfer-function zero suppression. The method is fully illustrated for a fourth-order stability-axis small-motion model with three lateral handling-quality time histories specified. The FORTRAN program which obtains and verifies the model is included and fully documented.

  18. Real-time damage monitoring scheme in PSC girder bridge using output-only acceleration data

    NASA Astrophysics Data System (ADS)

    Kim, Jeong-Tae; Park, Jae-Hyung; Do, Han-Sung; Lee, Jung-Mi

    2007-04-01

    Artificial neural networks (ANNs) have been increasingly utilized for structural health monitoring (SHM) due to the advantage that it needs only a few training data to detect damage in structures. In this study, a new damage monitoring method using a set of parallel ANNs and acceleration signals is developed for alarming locations of damage in PSC girder bridges. First, theoretical backgrounds are described. The problem addressed in this paper is defined as the stochastic process. In addition, a parallel ANN-algorithm using output-only acceleration responses is newly designed for damage detection in real time. The cross-covariance of two acceleration-signals measured at two different locations is selected as the feature representing the structural condition. Neural networks are trained for potential loading patterns and damage scenarios of the target structure for which its actual loadings are unknown. The feasibility of the proposed method is evaluated from numerical model tests on PSC beams for which accelerations were acquired before and after several damage cases.

  19. A consistent approach for the treatment of Fermi acceleration in time-dependent billiards

    NASA Astrophysics Data System (ADS)

    Karlis, A. K.; Diakonos, F. K.; Constantoudis, V.

    2012-06-01

    The standard description of Fermi acceleration, developing in a class of time-dependent billiards, is given in terms of a diffusion process taking place in momentum space. Within this framework, the evolution of the probability density function (PDF) of the magnitude of particle velocities as a function of the number of collisions n is determined by the Fokker-Planck equation (FPE). In the literature, the FPE is constructed by identifying the transport coefficients with the ensemble averages of the change of the magnitude of particle velocity and its square in the course of one collision. Although this treatment leads to the correct solution after a sufficiently large number of collisions have been reached, the transient part of the evolution of the PDF is not described. Moreover, in the case of the Fermi-Ulam model (FUM), if a standard simplification is employed, the solution of the FPE is even inconsistent with the values of the transport coefficients used for its derivation. The goal of our work is to provide a self-consistent methodology for the treatment of Fermi acceleration in time-dependent billiards. The proposed approach obviates any assumptions for the continuity of the random process and the existence of the limits formally defining the transport coefficients of the FPE. Specifically, we suggest, instead of the calculation of ensemble averages, the derivation of the one-step transition probability function and the use of the Chapman-Kolmogorov forward equation. This approach is generic and can be applied to any time-dependent billiard for the treatment of Fermi-acceleration. As a first step, we apply this methodology to the FUM, being the archetype of time-dependent billiards to exhibit Fermi acceleration.

  20. Real time monitoring of accelerated chemical reactions by ultrasonication-assisted spray ionization mass spectrometry.

    PubMed

    Lin, Shu-Hsuan; Lo, Ta-Ju; Kuo, Fang-Yin; Chen, Yu-Chie

    2014-01-01

    Ultrasonication has been used to accelerate chemical reactions. It would be ideal if ultrasonication-assisted chemical reactions could be monitored by suitable detection tools such as mass spectrometry in real time. It would be helpful to clarify reaction intermediates/products and to have a better understanding of reaction mechanism. In this work, we developed a system for ultrasonication-assisted spray ionization mass spectrometry (UASI-MS) with an ~1.7 MHz ultrasonic transducer to monitor chemical reactions in real time. We demonstrated that simply depositing a sample solution on the MHz-based ultrasonic transducer, which was placed in front of the orifice of a mass spectrometer, the analyte signals can be readily detected by the mass spectrometer. Singly and multiply charged ions from small and large molecules, respectively, can be observed in the UASI mass spectra. Furthermore, the ultrasonic transducer used in the UASI setup accelerates the chemical reactions while being monitored via UASI-MS. The feasibility of using this approach for real-time acceleration/monitoring of chemical reactions was demonstrated. The reactions of Girard T reagent and hydroxylamine with steroids were used as the model reactions. Upon the deposition of reactant solutions on the ultrasonic transducer, the intermediate/product ions are readily generated and instantaneously monitored using MS within 1 s. Additionally, we also showed the possibility of using this reactive UASI-MS approach to assist the confirmation of trace steroids from complex urine samples by monitoring the generation of the product ions.

  1. Relativistic electron acceleration and decay time scales in the inner and outer radiation belts: SAMPEX

    NASA Technical Reports Server (NTRS)

    Baker, D. N.; Blake, J. B.; Callis, L. B.; Cummings, J. R.; Hovestadt, D.; Kanekal, S.; Klecker, B.; Mewaldt, R. A.; Zwickl, R. D.

    1994-01-01

    High-energy electrons have been measured systematically in a low-altitude (520 x 675 km), nearly polar (inclination = 82 deg) orbit by sensitive instruments onboard the Solar, Anomalous, and Magnetospheric Particle Explorer (SAMPEX). Count rate channels with electron energy thresholds ranging from 0.4 MeV to 3.5 MeV in three different instruments have been used to examine relativistic electron variations as a function of L-shell parameter and time. A long run of essentially continuous data (July 1992 - July 1993) shows substantial acceleration of energetic electrons throughout much of the magnetosphere on rapid time scales. This acceleration appears to be due to solar wind velocity enhancements and is surprisingly large in that the radiation belt 'slot' region often is filled temporarily and electron fluxes are strongly enhanced even at very low L-values (L aprroximately 2). A superposed epoch analysis shows that electron fluxes rise rapidly for 2.5 is approximately less than L is approximately less than 5. These increases occur on a time scale of order 1-2 days and are most abrupt for L-values near 3. The temporal decay rate of the fluxes is dependent on energy and L-value and may be described by J = Ke-t/to with t(sub o) approximately equals 5-10 days. Thus, these results suggest that the Earth's magnetosphere is a cosmic electron accelerator of substantial strength and efficiency.

  2. Ten scenarios from early radiation to late time acceleration with a minimally coupled dark energy

    SciTech Connect

    Fay, Stéphane

    2013-09-01

    We consider General Relativity with matter, radiation and a minimally coupled dark energy defined by an equation of state w. Using dynamical system method, we find the equilibrium points of such a theory assuming an expanding Universe and a positive dark energy density. Two of these points correspond to classical radiation and matter dominated epochs for the Universe. For the other points, dark energy mimics matter, radiation or accelerates Universe expansion. We then look for possible sequences of epochs describing a Universe starting with some radiation dominated epoch(s) (mimicked or not by dark energy), then matter dominated epoch(s) (mimicked or not by dark energy) and ending with an accelerated expansion. We find ten sequences able to follow this Universe history without singular behaviour of w at some saddle points. Most of them are new in dark energy literature. To get more than these ten sequences, w has to be singular at some specific saddle equilibrium points. This is an unusual mathematical property of the equation of state in dark energy literature, whose physical consequences tend to be discarded by observations. This thus distinguishes the ten above sequences from an infinity of ways to describe Universe expansion.

  3. Effect of prolonged bedrest and plus Gz acceleration on peripheral visual response time

    NASA Technical Reports Server (NTRS)

    Haines, R. F.

    1973-01-01

    Peripheral visual response time changes during +G sub z acceleration following fourteen days of bedrest are considered as well as what effect prolonged bedrest has upon this response. Eighteen test lights, placed 10 deg are apart along the horizontal meridian of the subject's field of view, were presented in a random sequence. The subject was instructed to press a button as soon as a light appeared. Response time testing occurred periodically during bedrest and continuously during centrifugation testing. The results indicate that: (1) mean response time is significantly longer to stimuli imaged in the far periphery than to stimuli imaged closer to the line of sight; (2) mean response time at each stimulus position tends to be longer at plateau g than during the preacceleration baseline period; (3) mean response time tends to lengthen as the g level is increased; (4) peripheral visual response time during +G sub x acceleration at 2, 3.2, and 3.8 g was not a reliable advanced indicator that blackout was going to occur; and (5) the subject's field of view collapsed rapidly just before blackout. Bedrest data showed that the distribution of response times to stimuli imaged across the subject's horizontal retinal meridian remained remarkably constant from day to day during both the bedrest and recovery periods.

  4. Time-dependent modeling of solar wind acceleration from turbulent heating in open flux tubes

    NASA Astrophysics Data System (ADS)

    Woolsey, Lauren Nicole; Cranmer, Steven R.

    2015-04-01

    The acceleration of the solar wind, particularly from open flux tubes, remains an open question in solar physics. Countless physical processes have been suggested to explain all or parts of the coupled problem of coronal heating and wind acceleration, but the current generation of observations have been so far unable to distinguish which mechanism(s) dominates. In this project, we consider heating by Alfvén waves in a three-dimensional, time-dependent reduced magnetohydrodynamics model. This model solves for the heating rate as a function of time due to the twisting and braiding of magnetic field lines within a flux tube, which is caused by Alfvén waves generated at the single footpoint of the flux tube. We investigate three specific structures commonly found in the corona: 1) an open flux tube in a coronal hole, 2) an open flux tube on the edge of an equatorial streamer, and 3) an open flux tube directly neighboring an active region. We present the time-dependent heating rate, power spectra of fluctuations, and the time-averaged properties of the solar wind arising from each magnetic structure. We compare the time-averaged properties from the present modeling with previous results from a one-dimensional, time-steady code (Cranmer et al. 2007) to better calibrate the physics in the lower-dimensional code and get a better understanding of the intricate role that bursty, transient heating from Alfvén-wave-driven turbulence plays in the acceleration of the solar wind from different magnetic structures.

  5. Accelerating universe and the time-dependent fine-structure constant

    NASA Astrophysics Data System (ADS)

    Fujii, Yasunori

    2010-11-01

    I start with assuming a gravitational scalar field as the dark-energy supposed to be responsible for the accelerating universe. Also from the point of view of unification, a scalar field implies a time-variability of certain “constants” in Nature. In this context I once derived a relation for the time-variability of the fine-structure constant α: Δα/α =ζ Ƶ(α/π) Δσ, where ζ and Ƶ are the constants of the order one, while σ on the right-hand side is the scalar field in action in the accelerating universe. I use the reduced Planckian units with c=ℏ =MP(=(8π G)-1/2)=1. I then compared the dynamics of the accelerating universe, on one hand, and Δα/α derived from the analyses of QSO absorption lines, Oklo phenomenon, also different atomic clocks in the laboratories, on the other hand. I am here going to discuss the theoretical background of the relation, based on the scalar-tensor theory invented first by Jordan in 1955.

  6. Freezing, accelerating, and slowing directed currents in real time with superimposed driven lattices

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, Aritra K.; Liebchen, Benno; Wulf, Thomas; Schmelcher, Peter

    2016-05-01

    We provide a generic scheme offering real-time control of directed particle transport using superimposed driven lattices. This scheme allows one to accelerate, slow, and freeze the transport on demand by switching one of the lattices subsequently on and off. The underlying physical mechanism hinges on a systematic opening and closing of channels between transporting and nontransporting phase space structures upon switching and exploits cantori structures which generate memory effects in the population of these structures. Our results should allow for real-time control of cold thermal atomic ensembles in optical lattices but might also be useful as a design principle for targeted delivery of molecules or colloids in optical devices.

  7. Application of real-time digitization techniques in beam measurement for accelerators

    NASA Astrophysics Data System (ADS)

    Zhao, Lei; Zhan, Lin-Song; Gao, Xing-Shun; Liu, Shu-Bin; An, Qi

    2016-04-01

    Beam measurement is very important for accelerators. In this paper, modern digital beam measurement techniques based on IQ (In-phase & Quadrature-phase) analysis are discussed. Based on this method and high-speed high-resolution analog-to-digital conversion, we have completed three beam measurement electronics systems designed for the China Spallation Neutron Source (CSNS), Shanghai Synchrotron Radiation Facility (SSRF), and Accelerator Driven Sub-critical system (ADS). Core techniques of hardware design and real-time system calibration are discussed, and performance test results of these three instruments are also presented. Supported by National Natural Science Foundation of China (11205153, 10875119), Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-N27), and the Fundamental Research Funds for the Central Universities (WK2030040029),and the CAS Center for Excellence in Particle Physics (CCEPP).

  8. Time trends in pathologic features of radical prostatectomy--impact of family history.

    PubMed

    Marotte, Jeffrey B; Ferrari, Michelle K; McNeal, John E; Brooks, James D; Presti, Joseph C

    2004-01-01

    We investigated whether the clinical or pathological features of patients with a family history of prostate cancer treated by radical prostatectomy differ from patients without a family history. A retrospective analysis of patients treated by radical prostatectomy between 1989 through 2000 was performed. The clinical and pathologic features of patients with a family history (defined as at least one first-degree relative with prostate cancer, N = 103) were compared with those with no family history (N = 456). In addition, the patients were stratified into two groups, those treated from 1989 through 1992 and those treated after 1992. In the entire cohort from 1989 through 2000, patients with a family history had a greater proportion of well-differentiated tumors than the NFH group (26.2% vs. 17.8%; P = 0.05). From 1989 to 1992 there was no statistical difference between patients with a family history (FH) and those without a family history (NFH) with respect to age, prostate specific antigen (PSA), PSA density, clinical or pathologic stage, Gleason grade, or total tumor volume. However, after 1992 the FH group tended to be younger than the NFH group (61.1 vs. 63.4; P = 0.02) and have a lower PSA (6.8 vs. 7.9; P = 0.01) at the time of diagnosis. We believe these differences are predominantly driven by more aggressive screening in patients with a family history of prostate cancer rather than any true genetic differences.

  9. Evaluation of Linear Accelerator Gating With Real-Time Electromagnetic Tracking

    SciTech Connect

    Smith, Ryan L.; Lechleiter, Kristen; Malinowski, Kathleen; Shepard, D.M.; Housley, D.J.; Afghan, M.; Newell, Jeff; Petersen, Jay; Sargent, Brian; Parikh, Parag

    2009-07-01

    Purpose: Intrafraction organ motion can produce dosimetric errors in radiotherapy. Commonly, the linear accelerator is gated using real-time breathing phase obtained by way of external sensors. However, the external anatomy does not always correlate well with the internal position. We examined a beam gating technique using signals from implanted wireless transponders that provided real-time feedback on the tumor location without an imaging dose to the patient. Methods and Materials: An interface was developed between Calypso Medical's four-dimensional electromagnetic tracking system and a Varian Trilogy linear accelerator. A film phantom was mounted on a motion platform programmed with lung motion trajectories. Deliveries were performed when the beam was gated according to the signal from the wireless transponders. The dosimetric advantages of beam gating and the system latencies were quantified. Results: Beam gating using on internal position monitoring provided up to a twofold increase in the dose gradients. The percentage of points failing to be within {+-}10 cGy of the planned dose (maximal dose, {approx}200 cGy) was 3.4% for gating and 32.1% for no intervention in the presence of motion. The mean latencies between the transponder position and linear accelerator modulation were 75.0 {+-}12.7 ms for beam on and 65.1 {+-} 12.9 ms for beam off. Conclusion: We have presented the results from a novel method for gating the linear accelerator using trackable wireless internal fiducial markers without the use of ionizing radiation for imaging. The latencies observed were suitable for gating using electromagnetic fiducial markers, which results in dosimetric improvements for irradiation in the presence of motion.

  10. Constraints on cosmological models and reconstructing the acceleration history of the Universe with gamma-ray burst distance indicators

    SciTech Connect

    Liang Nan; Wu Puxun; Zhang Shuangnan

    2010-04-15

    Gamma-ray bursts (GRBs) have been regarded as standard candles at very high redshift for cosmology research. We have proposed a new method to calibrate GRB distance indicators with Type Ia supernova (SNe Ia) data in a completely cosmology-independent way to avoid the circularity problem that had limited the direct use of GRBs to probe cosmology [N. Liang, W. K. Xiao, Y. Liu, and S. N. Zhang, Astrophys. J. 685, 354 (2008).]. In this paper, a simple method is provided to combine GRB data into the joint observational data analysis to constrain cosmological models; in this method those SNe Ia data points used for calibrating the GRB data are not used to avoid any correlation between them. We find that the {Lambda}CDM model is consistent with the joint data in the 1-{sigma} confidence region, using the GRB data at high redshift calibrated with the interpolating method, the Constitution set of SNe Ia, the cosmic microwave background radiation from Wilkinson Microwave Anisotropy Probe five year observation, the baryonic acoustic oscillation from the spectroscopic Sloan Digital Sky Survey Data Release 7 galaxy sample, the x-ray baryon mass fraction in clusters of galaxies, and the observational Hubble parameter versus redshift data. Comparing to the joint constraints with GRBs and without GRBs, we find that the contribution of GRBs to the joint cosmological constraints is a slight shift in the confidence regions of cosmological parameters to better enclose the {Lambda}CDM model. Finally, we reconstruct the acceleration history of the Universe up to z>6 with the distance moduli of SNe Ia and GRBs and find some features that deviate from the {Lambda}CDM model and seem to favor oscillatory cosmology models; however, further investigations are needed to better understand the situation.

  11. Analysis of accelerated failure time data with dependent censoring using auxiliary variables via nonparametric multiple imputation.

    PubMed

    Hsu, Chiu-Hsieh; Taylor, Jeremy M G; Hu, Chengcheng

    2015-08-30

    We consider the situation of estimating the marginal survival distribution from censored data subject to dependent censoring using auxiliary variables. We had previously developed a nonparametric multiple imputation approach. The method used two working proportional hazards (PH) models, one for the event times and the other for the censoring times, to define a nearest neighbor imputing risk set. This risk set was then used to impute failure times for censored observations. Here, we adapt the method to the situation where the event and censoring times follow accelerated failure time models and propose to use the Buckley-James estimator as the two working models. Besides studying the performances of the proposed method, we also compare the proposed method with two popular methods for handling dependent censoring through the use of auxiliary variables, inverse probability of censoring weighted and parametric multiple imputation methods, to shed light on the use of them. In a simulation study with time-independent auxiliary variables, we show that all approaches can reduce bias due to dependent censoring. The proposed method is robust to misspecification of either one of the two working models and their link function. This indicates that a working proportional hazards model is preferred because it is more cumbersome to fit an accelerated failure time model. In contrast, the inverse probability of censoring weighted method is not robust to misspecification of the link function of the censoring time model. The parametric imputation methods rely on the specification of the event time model. The approaches are applied to a prostate cancer dataset.

  12. User's manual for THPLOT, A FORTRAN 77 Computer program for time history plotting

    NASA Technical Reports Server (NTRS)

    Murray, J. E.

    1982-01-01

    A general purpose FORTRAN 77 computer program (THPLOT) for plotting time histories using Calcomp pen plotters is described. The program is designed to read a time history data file and to generate time history plots for selected time intervals and/or selected data channels. The capabilities of the program are described. The card input required to define the plotting operation is described and examples of card input and the resulting plotted output are given. The examples are followed by a description of the printed output, including both normal output and error messages. Lastly, implementation of the program is described. A complete listing of the program with reference maps produced by the CDC FTN 5.0 compiler is included.

  13. Nonsingular exponential gravity: A simple theory for early- and late-time accelerated expansion

    SciTech Connect

    Elizalde, E.; Odintsov, S. D.; Sebastiani, L.; Zerbini, S.

    2011-04-15

    A theory of exponential modified gravity which explains both early-time inflation and late-time acceleration, in a unified way, is proposed. The theory successfully passes the local tests and fulfills the cosmological bounds and, remarkably, the corresponding inflationary era is proven to be unstable. Numerical investigation of its late-time evolution leads to the conclusion that the corresponding dark energy epoch is not distinguishable from the one for the {Lambda}CDM model. Several versions of this exponential gravity, sharing similar properties, are formulated. It is also shown that this theory is nonsingular, being protected against the formation of finite-time future singularities. As a result, the corresponding future universe evolution asymptotically tends, in a smooth way, to de Sitter space, which turns out to be the final attractor of the system.

  14. A School-Wide Effort for Learning History via a Time Capsule

    ERIC Educational Resources Information Center

    Rowell, C. Glennon; Hickey, M. Gail; Gecsei, Kendall; Klein, Stacy

    2007-01-01

    In this article, the authors describe how a time capsule project helped students at Ridgedale Elementary School in Knoxville, Tennessee understand the nature of events and the relationships of events in a segment of history. The time capsule preparation motivated students to hypothesize about important events and significant artifacts of their…

  15. Science in History, Volume 3: The Natural Sciences in Our Time.

    ERIC Educational Resources Information Center

    Bernal, J. D.

    This volume, the third of four, includes part six of the eight parts in the series. The author writes of a "second scientific revolution" in the twentieth century and states "for the first time in history science and scientists have been involved directly and overtly in the major economic, industrial, and military developments of their time." This…

  16. A Time Sequence-Oriented Concept Map Approach to Developing Educational Computer Games for History Courses

    ERIC Educational Resources Information Center

    Chu, Hui-Chun; Yang, Kai-Hsiang; Chen, Jing-Hong

    2015-01-01

    Concept maps have been recognized as an effective tool for students to organize their knowledge; however, in history courses, it is important for students to learn and organize historical events according to the time of their occurrence. Therefore, in this study, a time sequence-oriented concept map approach is proposed for developing a game-based…

  17. Time-resolved energy spectrum measurement of a linear induction accelerator with the magnetic analyzer

    NASA Astrophysics Data System (ADS)

    Wang, Yuan; Jiang, Xiao-Guo; Yang, Guo-Jun; Chen, Si-Fu; Zhang, Zhuo; Wei, Tao; Li, Jin

    2015-01-01

    We recently set up a time-resolved optical beam diagnostic system. Using this system, we measured the high current electron beam energy in the accelerator under construction. This paper introduces the principle of the diagnostic system, describes the setup, and shows the results. A bending beam line was designed using an existing magnetic analyzer with a 300 mm-bending radius and a 60° bending angle at hard-edge approximation. Calculations show that the magnitude of the beam energy is about 18 MeV, and the energy spread is within 2%. Our results agree well with the initial estimates deduced from the diode voltage approach.

  18. Protecting and accelerating adiabatic passage with time-delayed pulse sequences.

    PubMed

    Sampedro, Pablo; Chang, Bo Y; Sola, Ignacio R

    2016-05-21

    Using numerical simulations of two-photon electronic absorption with femtosecond pulses in Na2 we show that: (i) it is possible to avoid the characteristic saturation or dumped Rabi oscillations in the yield of absorption by time-delaying the laser pulses; (ii) it is possible to accelerate the onset of adiabatic passage by using the vibrational coherence starting in a wave packet; and (iii) it is possible to prepare the initial wave packet in order to achieve full state-selective transitions with broadband pulses. The findings can be used, for instance, to achieve ultrafast adiabatic passage by light-induced potentials and understand its intrinsic robustness. PMID:27125342

  19. Protecting and accelerating adiabatic passage with time-delayed pulse sequences.

    PubMed

    Sampedro, Pablo; Chang, Bo Y; Sola, Ignacio R

    2016-05-21

    Using numerical simulations of two-photon electronic absorption with femtosecond pulses in Na2 we show that: (i) it is possible to avoid the characteristic saturation or dumped Rabi oscillations in the yield of absorption by time-delaying the laser pulses; (ii) it is possible to accelerate the onset of adiabatic passage by using the vibrational coherence starting in a wave packet; and (iii) it is possible to prepare the initial wave packet in order to achieve full state-selective transitions with broadband pulses. The findings can be used, for instance, to achieve ultrafast adiabatic passage by light-induced potentials and understand its intrinsic robustness.

  20. Simulating the effects of timing and energy stability in a laser wakefield accelerator with external injection

    SciTech Connect

    Dijk, W. van; Corstens, J. M.; Stragier, X. F. D.; Brussaard, G. J. H.; Geer, S. B. van der

    2009-01-22

    One of the most compelling reasons to use external injection of electrons into a laser wakefield accelerator is to improve the stability and reproducibility of the accelerated electrons. We have built a simulation tool based on particle tracking to investigate the expected output parameters. Specifically, we are simulating the variations in energy and bunch charge under the influence of variations in laser power and timing jitter. In these simulations a a{sub 0} = 0.32 to a{sub 0} = 1.02 laser pulse with 10% shot-to-shot energy fluctuation is focused into a plasma waveguide with a density of 1.0x10{sup 24} m{sup -3} and a calculated matched spot size of 50.2 {mu}m. The timing of the injected electron bunch with respect to the laser pulse is varied from up to 1 ps from the standard timing (1 ps ahead or behind the laser pulse, depending on the regime). The simulation method and first results will be presented. Shortcomings and possible extensions to the model will be discussed.

  1. A shell-derived time history of bomb {sup 14}C on Georges Bank and its Labrador Sea implications

    SciTech Connect

    Weidman, C.R.; Jones, G.A.

    1993-08-15

    Bomb-produced radiocarbon has been used in the past as an important tracer of ocean circulation and as a valuable tool for calculating CO{sub 2} air-sea exchange. However, previous studies of the ocean`s time-varying bomb {sup 14}C record have been confined exclusively to analyzing banded corals, and thus their application has been limited to the lower latitudes. The first time history of bomb {sup 14}C from the high-latitude North Atlantic Ocean is obtained from a 54-year-old mollusc specimen, (Bivalvia) Arctica islandica, which was collected live from Georges Bank (41{degrees}N) in 1990. The annual growth bands of its shell were analyzed for {Delta}{sup 14}C using accelerator mass spectrometry, producing a {Delta}{sup 14}C time history from 1939 to 1990. The depleted condition of the Georges Bank bomb {sup 14}C signal relative to two coral-derived North Atlantic {Delta}{sup 14}C time histories suggests a significant deepwater source for the waters on Georges Bank. Supported by previous work linking the origin of waters on Georges Bank to the Labrador Sea, the {Delta}{sup 14}C budget on Georges Bank is modeled as Labrador Sea water, which largely becomes confined to the shelf and partially equilibrates with the atmosphere during a 1-year transit time from the Labrador Sea to Georges Bank. This model is also used to estimate a time history of bomb {sup 14}C for the Labrador Sea. Prebomb {Delta}{sup 14}C values calculated for the surface Labrador Sea suggest that a greater inventory of bomb {sup 14}C has accumulated here than has previously been reported. Deduced variations in the ventilation and/or {sup 14}CO{sub 2} uptake rates in the Labrador Sea correspond with observed changes in surface salinity of the Labrador Sea, suggesting a reduction in deepwater formation during the late 1960s and 1970s. 59 refs., 11 figs., 2 tabs.

  2. Accelerating Time Integration for the Shallow Water Equations on the Sphere Using GPUs

    DOE PAGES

    Archibald, R.; Evans, K. J.; Salinger, A.

    2015-06-01

    The push towards larger and larger computational platforms has made it possible for climate simulations to resolve climate dynamics across multiple spatial and temporal scales. This direction in climate simulation has created a strong need to develop scalable time-stepping methods capable of accelerating throughput on high performance computing. This work details the recent advances in the implementation of implicit time stepping on a spectral element cube-sphere grid using graphical processing units (GPU) based machines. We demonstrate how solvers in the Trilinos project are interfaced with ACME and GPU kernels can significantly increase computational speed of the residual calculations in themore » implicit time stepping method for the shallow water equations on the sphere. We show the optimization gains and data structure reorganization that facilitates the performance improvements.« less

  3. Accelerating Time Integration for the Shallow Water Equations on the Sphere Using GPUs

    SciTech Connect

    Archibald, R.; Evans, K. J.; Salinger, A.

    2015-06-01

    The push towards larger and larger computational platforms has made it possible for climate simulations to resolve climate dynamics across multiple spatial and temporal scales. This direction in climate simulation has created a strong need to develop scalable time-stepping methods capable of accelerating throughput on high performance computing. This work details the recent advances in the implementation of implicit time stepping on a spectral element cube-sphere grid using graphical processing units (GPU) based machines. We demonstrate how solvers in the Trilinos project are interfaced with ACME and GPU kernels can significantly increase computational speed of the residual calculations in the implicit time stepping method for the shallow water equations on the sphere. We show the optimization gains and data structure reorganization that facilitates the performance improvements.

  4. A charged particle in a homogeneous magnetic field accelerated by a time-periodic Aharonov-Bohm flux

    SciTech Connect

    Kalvoda, T.; Stovicek, P.

    2011-10-15

    We consider a nonrelativistic quantum charged particle moving on a plane under the influence of a uniform magnetic field and driven by a periodically time-dependent Aharonov-Bohm flux. We observe an acceleration effect in the case when the Aharonov-Bohm flux depends on time as a sinusoidal function whose frequency is in resonance with the cyclotron frequency. In particular, the energy of the particle increases linearly for large times. An explicit formula for the acceleration rate is derived with the aid of the quantum averaging method, and then it is checked against a numerical solution and a very good agreement is found. - Highlights: > A nonrelativistic quantum charged particle on a plane. > A homogeneous magnetic field and a periodically time-dependent Aharonov-Bohm flux. > The quantum averaging method applied to a time-dependent system. > A resonance of the AB flux with the cyclotron frequency. > An acceleration with linearly increasing energy; a formula for the acceleration rate.

  5. Time dependent diffusive shock acceleration and its application to middle aged supernova remnants

    NASA Astrophysics Data System (ADS)

    Tang, Xiaping; Chevalier, Roger A.

    2016-06-01

    Recent gamma-ray observations show that middle aged supernova remnants (SNRs) interacting with molecular clouds (MCs) can be sources of both GeV and TeV emission. Based on the MC association, two scenarios have been proposed to explain the observed gamma-ray emission. In one, energetic cosmic ray (CR) particles escape from the SNR and then illuminate nearby MCs, producing gamma-ray emission, while the other involves direct interaction between the SNR and MC. In the direct interaction scenario, re-acceleration of pre-existing CRs in the ambient medium is investigated while particles injected from the thermal pool are neglected in view of the slow shock speeds in middle aged SNRs. However, standard diffusive shock acceleration (DSA) theory produces a steady state particle spectrum that is too flat compared to observations, which suggests that the high energy part of the observed spectrum has not yet reached a steady state. We derive a time dependent DSA solution in the test particle limit for re-acceleration of pre-existing CRs case and show that it is capable of reproducing the observed gamma-ray emission in SNRs like IC 443 and W44, in the context of a MC interaction model. We also provide a simple physical picture to understand the time dependent DSA spectrum. A spatially averaged diffusion coefficient around the SNR can be estimated through fitting the gamma-ray spectrum. The spatially averaged diffusion coefficient in middle aged SNRs like IC 443 and W44 is estimated to be ~10^(25) cm^2/s at ~ 1GeV, which is between the Bohm limit and interstellar value.

  6. Gauss-Bonnet cosmology unifying late and early-time acceleration eras with intermediate eras

    NASA Astrophysics Data System (ADS)

    Oikonomou, V. K.

    2016-07-01

    In this paper we demonstrate that with vacuum F(G) gravity it is possible to describe the unification of late and early-time acceleration eras with the radiation and matter domination era. The Hubble rate of the unified evolution contains two mild singularities, so called Type IV singularities, and the evolution itself has some appealing features, such as the existence of a deceleration-acceleration transition at late times. We also address quantitatively a fundamental question related to modified gravity models description of cosmological evolution: Is it possible for all modified gravity descriptions of our Universe evolution, to produce a nearly scale invariant spectrum of primordial curvature perturbations? As we demonstrate, the answer for the F(G) description is no, since the resulting power spectrum is not scale invariant, in contrast to the F(R) description studied in the literature. Therefore, although the cosmological evolution can be realized in the context of vacuum F(G) gravity, the evolution is not compatible with the observational data, in contrast to the F(R) gravity description of the same cosmological evolution.

  7. History-dependent friction and slow slip from time-dependent microscopic junction laws studied in a statistical framework.

    PubMed

    Thøgersen, Kjetil; Trømborg, Jørgen Kjoshagen; Sveinsson, Henrik Andersen; Malthe-Sørenssen, Anders; Scheibert, Julien

    2014-05-01

    To study how macroscopic friction phenomena originate from microscopic junction laws, we introduce a general statistical framework describing the collective behavior of a large number of individual microjunctions forming a macroscopic frictional interface. Each microjunction can switch in time between two states: a pinned state characterized by a displacement-dependent force and a slipping state characterized by a time-dependent force. Instead of tracking each microjunction individually, the state of the interface is described by two coupled distributions for (i) the stretching of pinned junctions and (ii) the time spent in the slipping state. This framework allows for a whole family of microjunction behavior laws, and we show how it represents an overarching structure for many existing models found in the friction literature. We then use this framework to pinpoint the effects of the time scale that controls the duration of the slipping state. First, we show that the model reproduces a series of friction phenomena already observed experimentally. The macroscopic steady-state friction force is velocity dependent, either monotonic (strengthening or weakening) or nonmonotonic (weakening-strengthening), depending on the microscopic behavior of individual junctions. In addition, slow slip, which has been reported in a wide variety of systems, spontaneously occurs in the model if the friction contribution from junctions in the slipping state is time weakening. Next, we show that the model predicts a nontrivial history dependence of the macroscopic static friction force. In particular, the static friction coefficient at the onset of sliding is shown to increase with increasing deceleration during the final phases of the preceding sliding event. We suggest that this form of history dependence of static friction should be investigated in experiments, and we provide the acceleration range in which this effect is expected to be experimentally observable.

  8. The effects of gait time and trunk acceleration ratio during stair climbing in old-old adult females.

    PubMed

    Shin, Sun-Shil; Yoo, Won-Gyu

    2016-07-01

    [Purpose] This study investigated the effects of gait time and trunk acceleration ratio in old-old adult females during stair climbing. [Subjects and Methods] Twenty-five older adult females who were able to walk independently volunteered for this study and were categorized into two age groups (older adults or old-old adults). Gait time and trunk acceleration ratio were measured using an accelerometer during stair climbing. [Results] Gait time and trunk acceleration ratio when climbing stairs were significantly higher in the old-old age group than in the older adults group. [Conclusions] These findings suggest that old-old females have decreased upper trunk control. In addition, gait time and the trunk acceleration ratio during stair climbing are useful clinical markers for predicting function and balance control ability in old-old elderly populations. PMID:27512256

  9. The effects of gait time and trunk acceleration ratio during stair climbing in old-old adult females

    PubMed Central

    Shin, Sun-Shil; Yoo, Won-Gyu

    2016-01-01

    [Purpose] This study investigated the effects of gait time and trunk acceleration ratio in old-old adult females during stair climbing. [Subjects and Methods] Twenty-five older adult females who were able to walk independently volunteered for this study and were categorized into two age groups (older adults or old-old adults). Gait time and trunk acceleration ratio were measured using an accelerometer during stair climbing. [Results] Gait time and trunk acceleration ratio when climbing stairs were significantly higher in the old-old age group than in the older adults group. [Conclusions] These findings suggest that old-old females have decreased upper trunk control. In addition, gait time and the trunk acceleration ratio during stair climbing are useful clinical markers for predicting function and balance control ability in old-old elderly populations. PMID:27512256

  10. Acceleration of yoghurt fermentation time by yeast extract and partial characterisation of the active components.

    PubMed

    Smith, Esti-Andrine; Myburgh, Jacobus; Osthoff, Gernot; de Wit, Maryna

    2014-11-01

    Water soluble autolysate of yeast, usually utilised for microbial growth support, was used as additive in yoghurt fermentation. The yeast extract (YE) resulted in a decrease of fermentation time by 21% to reach a pH of 4·6. However, the YE resulted in unacceptable flavour and taste. By size exclusion chromatography, a fraction of the YE was obtained that could account for the observed 21% decrease in fermentation time. The fraction contained molecules of low molecular weight, consisting of minerals, free amino acids and peptides. The acceleration of the yoghurt fermentation was ascribed to the short peptides in the fraction. It is proposed that the application of this extract in industrial yoghurt manufacture would result in savings for both the industry and the consumer.

  11. Accumulation of accelerated electrons in coronal loops and time delays of solar flare nonthermal emission

    NASA Astrophysics Data System (ADS)

    Tsap, Yu. T.; Stepanov, A. V.; Kopylova, Yu. G.

    2015-12-01

    The mechanisms by which accelerated electrons accumulate in flare loops with regard to the observed time delays between peaks of prolonged (≫1 s) hard X-ray pulses with different energies are considered. The focus is on an analysis of electron pitch-angle scattering by background plasma particles and/or turbulent pulsations in extreme cases of frequent and rare collisions. It was shown that it is difficult to explain the origination of time delays in the scope of a diffusion model when the electron free path length ( l) in the corona is smaller than the flare loop length ( L). The accumulation of energetic particles in loops at l > L is related to a trap-plus-precipitation model in which the regime of weak pitch angle diffusion of trapped electrons in the loss cone predominates.

  12. On the Impact of a Quadratic Acceleration Term in the Analysis of Position Time Series

    NASA Astrophysics Data System (ADS)

    Bogusz, Janusz; Klos, Anna; Bos, Machiel Simon; Hunegnaw, Addisu; Teferle, Felix Norman

    2016-04-01

    The analysis of Global Navigation Satellite System (GNSS) position time series generally assumes that each of the coordinate component series is described by the sum of a linear rate (velocity) and various periodic terms. The residuals, the deviations between the fitted model and the observations, are then a measure of the epoch-to-epoch scatter and have been used for the analysis of the stochastic character (noise) of the time series. Often the parameters of interest in GNSS position time series are the velocities and their associated uncertainties, which have to be determined with the highest reliability. It is clear that not all GNSS position time series follow this simple linear behaviour. Therefore, we have added an acceleration term in the form of a quadratic polynomial function to the model in order to better describe the non-linear motion in the position time series. This non-linear motion could be a response to purely geophysical processes, for example, elastic rebound of the Earth's crust due to ice mass loss in Greenland, artefacts due to deficiencies in bias mitigation models, for example, of the GNSS satellite and receiver antenna phase centres, or any combination thereof. In this study we have simulated 20 time series with different stochastic characteristics such as white, flicker or random walk noise of length of 23 years. The noise amplitude was assumed at 1 mm/y-/4. Then, we added the deterministic part consisting of a linear trend of 20 mm/y (that represents the averaged horizontal velocity) and accelerations ranging from minus 0.6 to plus 0.6 mm/y2. For all these data we estimated the noise parameters with Maximum Likelihood Estimation (MLE) using the Hector software package without taken into account the non-linear term. In this way we set the benchmark to then investigate how the noise properties and velocity uncertainty may be affected by any un-modelled, non-linear term. The velocities and their uncertainties versus the accelerations for

  13. Discrete-Time Survival Factor Mixture Analysis for Low-Frequency Recurrent Event Histories

    PubMed Central

    Masyn, Katherine E.

    2013-01-01

    In this article, the latent class analysis framework for modeling single event discrete-time survival data is extended to low-frequency recurrent event histories. A partial gap time model, parameterized as a restricted factor mixture model, is presented and illustrated using juvenile offending data. This model accommodates event-specific baseline hazard probabilities and covariate effects; event recurrences within a single time period; and accounts for within- and between-subject correlations of event times. This approach expands the family of latent variable survival models in a way that allows researchers to explicitly address questions about unobserved heterogeneity in the timing of events across the lifespan. PMID:24489519

  14. The Past Is All before Us: The History of Education in Hard Times

    ERIC Educational Resources Information Center

    Jones, Ken

    2012-01-01

    In this article, the author explores these questions--from what position, with what focus, and through what methods can a history be produced that is sensible of the conflicts and passions of its own time, and that can illuminate those of the past?--estimating that the books under review in several ways invite such a demanding reading. Gary…

  15. The timing of life-history events in a changing climate.

    PubMed Central

    Post, E; Forchhammer, M C; Stenseth, N C; Callaghan, T V

    2001-01-01

    Although empirical and theoretical studies suggest that climate influences the timing of life-history events in animals and plants, correlations between climate and the timing of events such as egg-laying, migration or flowering do not reveal the mechanisms by which natural selection operates on life-history events. We present a general autoregressive model of the timing of life-history events in relation to variation in global climate that, like autoregressive models of population dynamics, allows for a more mechanistic understanding of the roles of climate, resources and competition. We applied the model to data on 50 years of annual dates of first flowering by three species of plants in 26 populations covering 4 degrees of latitude in Norway. In agreement with earlier studies, plants in most populations and all three species bloomed earlier following warmer winters. Moreover, our model revealed that earlier blooming reflected increasing influences of resources and density-dependent population limitation under climatic warming. The insights available from the application of this model to phenological data in other taxa will contribute to our understanding of the roles of endogenous versus exogenous processes in the evolution of the timing of life-history events in a changing climate. PMID:12123293

  16. The Understanding of Historical Time in the Primary History Curriculum in England and the Netherlands

    ERIC Educational Resources Information Center

    De Groot-Reuvekamp, M. J.; Van Boxtel, Carla; Ros, Anje; Harnett, Penelope

    2014-01-01

    This study focuses on the comparison of the English and the Dutch primary history curriculum regarding the understanding of historical time. We compare different aspects of both curricula that can apply to other subjects as well, for example the question "what age would be appropriate to start a subject in primary school?" Here, we…

  17. The timing of life-history events in a changing climate.

    PubMed

    Post, E; Forchhammer, M C; Stenseth, N C; Callaghan, T V

    2001-01-01

    Although empirical and theoretical studies suggest that climate influences the timing of life-history events in animals and plants, correlations between climate and the timing of events such as egg-laying, migration or flowering do not reveal the mechanisms by which natural selection operates on life-history events. We present a general autoregressive model of the timing of life-history events in relation to variation in global climate that, like autoregressive models of population dynamics, allows for a more mechanistic understanding of the roles of climate, resources and competition. We applied the model to data on 50 years of annual dates of first flowering by three species of plants in 26 populations covering 4 degrees of latitude in Norway. In agreement with earlier studies, plants in most populations and all three species bloomed earlier following warmer winters. Moreover, our model revealed that earlier blooming reflected increasing influences of resources and density-dependent population limitation under climatic warming. The insights available from the application of this model to phenological data in other taxa will contribute to our understanding of the roles of endogenous versus exogenous processes in the evolution of the timing of life-history events in a changing climate.

  18. American History Time Lines. Grades 4-8. Big, Reproducible, Easy-To-Use.

    ERIC Educational Resources Information Center

    Buckley, Susan Washburn

    This resource is designed to enhance learning about topics in United States history. The reproducible time lines are easy to use and is designed to encourage students to research other dates and events of the era under study. Suggestions are given for classroom use. The introduction has instructional subjects, such as: "12 Great Ways To Use These…

  19. The History and Timing of Depression Onset as Predictors of Young Adult Self-Esteem

    ERIC Educational Resources Information Center

    Gayman, Mathew D.; Lloyd, Donald A.; Ueno, Koji

    2011-01-01

    Depression often emerges early in the lifecourse and is consistently shown to be associated with poor self-esteem. The 3 main objectives of the current study are to (1) evaluate the association between a history major depression and self-esteem in young adulthood, (2) assess the relationship between timing of depression onset and young adult…

  20. Real time wave forecasting using wind time history and numerical model

    NASA Astrophysics Data System (ADS)

    Jain, Pooja; Deo, M. C.; Latha, G.; Rajendran, V.

    Operational activities in the ocean like planning for structural repairs or fishing expeditions require real time prediction of waves over typical time duration of say a few hours. Such predictions can be made by using a numerical model or a time series model employing continuously recorded waves. This paper presents another option to do so and it is based on a different time series approach in which the input is in the form of preceding wind speed and wind direction observations. This would be useful for those stations where the costly wave buoys are not deployed and instead only meteorological buoys measuring wind are moored. The technique employs alternative artificial intelligence approaches of an artificial neural network (ANN), genetic programming (GP) and model tree (MT) to carry out the time series modeling of wind to obtain waves. Wind observations at four offshore sites along the east coast of India were used. For calibration purpose the wave data was generated using a numerical model. The predicted waves obtained using the proposed time series models when compared with the numerically generated waves showed good resemblance in terms of the selected error criteria. Large differences across the chosen techniques of ANN, GP, MT were not noticed. Wave hindcasting at the same time step and the predictions over shorter lead times were better than the predictions over longer lead times. The proposed method is a cost effective and convenient option when a site-specific information is desired.

  1. Real-time diagnostic for charging and damage of dielectrics in accelerators

    NASA Astrophysics Data System (ADS)

    Shchelkunov, S. V.; Marshall, T. C.; Hirshfield, J. L.

    2016-09-01

    We report on the progress made during the initial stage of our research to study charging rate and charge distribution in a thin walled dielectric wakefield accelerator (DWA) from a passing charge bunch and the physics of conductivity and discharge phenomena in dielectric materials useful in accelerator applications. The issue is the role played by the beam halo and intense wakefields in charging the dielectric, possibly leading to undesired deflection of charge bunches and degradation of the dielectric material: the effects that may grow over many pulses, albeit perhaps differently at different repetition rates. During the initial stage of development, a microwave apparatus was built and signal processing was developed to observe time-dependent charging of dielectric surfaces and/or plasmas located on or near the inner surface of a thin-wall hollow dielectric tube. Three frequencies were employed to improve the data handling rate and the signal-to-noise. The test and performance results for a plasma test case are presented; in particular, the performance of the test unit shows capability to detect small changes ~0.1% of a dielectric constant, which would correspond to the scraping-off of only 0.3 nC to the walls of the dielectric liner inside the cavity from the passing charge bunch.

  2. Time-dependent Models for Blazar Emission with the Second-order Fermi Acceleration

    NASA Astrophysics Data System (ADS)

    Asano, Katsuaki; Takahara, Fumio; Kusunose, Masaaki; Toma, Kenji; Kakuwa, Jun

    2014-01-01

    The second-order Fermi acceleration (Fermi-II) driven by turbulence may be responsible for the electron acceleration in blazar jets. We test this model with time-dependent simulations. The hard electron spectrum predicted by the Fermi-II process agrees with the hard photon spectrum of 1ES 1101-232. For other blazars that show softer spectra, the Fermi-II model requires radial evolution of the electron injection rate and/or diffusion coefficient in the outflow. Such evolutions can yield a curved electron spectrum, which can reproduce the synchrotron spectrum of Mrk 421 from the radio to the X-ray regime. The photon spectrum in the GeV energy range of Mrk 421 is hard to fit with a synchrotron self-Compton model. However, if we introduce an external radio photon field with a luminosity of 4.9 × 1038 erg s-1, GeV photons are successfully produced via inverse Compton scattering. The temporal variability of the diffusion coefficient or injection rate causes flare emission. The observed synchronicity of X-ray and TeV flares implies a decrease of the magnetic field in the flaring source region.

  3. Time-dependent models for blazar emission with the second-order Fermi acceleration

    SciTech Connect

    Asano, Katsuaki; Takahara, Fumio; Toma, Kenji; Kusunose, Masaaki; Kakuwa, Jun

    2014-01-01

    The second-order Fermi acceleration (Fermi-II) driven by turbulence may be responsible for the electron acceleration in blazar jets. We test this model with time-dependent simulations. The hard electron spectrum predicted by the Fermi-II process agrees with the hard photon spectrum of 1ES 1101–232. For other blazars that show softer spectra, the Fermi-II model requires radial evolution of the electron injection rate and/or diffusion coefficient in the outflow. Such evolutions can yield a curved electron spectrum, which can reproduce the synchrotron spectrum of Mrk 421 from the radio to the X-ray regime. The photon spectrum in the GeV energy range of Mrk 421 is hard to fit with a synchrotron self-Compton model. However, if we introduce an external radio photon field with a luminosity of 4.9 × 10{sup 38} erg s{sup –1}, GeV photons are successfully produced via inverse Compton scattering. The temporal variability of the diffusion coefficient or injection rate causes flare emission. The observed synchronicity of X-ray and TeV flares implies a decrease of the magnetic field in the flaring source region.

  4. Analytic approach to nonlinear hydrodynamic instabilities driven by time-dependent accelerations

    SciTech Connect

    Mikaelian, K O

    2009-09-28

    We extend our earlier model for Rayleigh-Taylor and Richtmyer-Meshkov instabilities to the more general class of hydrodynamic instabilities driven by a time-dependent acceleration g(t) . Explicit analytic solutions for linear as well as nonlinear amplitudes are obtained for several g(t)'s by solving a Schroedinger-like equation d{sup 2}{eta}/dt{sup 2} - g(t)kA{eta} = 0 where A is the Atwood number and k is the wavenumber of the perturbation amplitude {eta}(t). In our model a simple transformation k {yields} k{sub L} and A {yields} A{sub L} connects the linear to the nonlinear amplitudes: {eta}{sup nonlinear} (k,A) {approx} (1/k{sub L})ln{eta}{sup linear} (k{sub L}, A{sub L}). The model is found to be in very good agreement with direct numerical simulations. Bubble amplitudes for a variety of accelerations are seen to scale with s defined by s = {integral} {radical}g(t)dt, while spike amplitudes prefer scaling with displacement {Delta}x = {integral}[{integral}g(t)dt]dt.

  5. BICEP's acceleration

    SciTech Connect

    Contaldi, Carlo R.

    2014-10-01

    The recent Bicep2 [1] detection of, what is claimed to be primordial B-modes, opens up the possibility of constraining not only the energy scale of inflation but also the detailed acceleration history that occurred during inflation. In turn this can be used to determine the shape of the inflaton potential V(φ) for the first time — if a single, scalar inflaton is assumed to be driving the acceleration. We carry out a Monte Carlo exploration of inflationary trajectories given the current data. Using this method we obtain a posterior distribution of possible acceleration profiles ε(N) as a function of e-fold N and derived posterior distributions of the primordial power spectrum P(k) and potential V(φ). We find that the Bicep2 result, in combination with Planck measurements of total intensity Cosmic Microwave Background (CMB) anisotropies, induces a significant feature in the scalar primordial spectrum at scales k∼ 10{sup -3} Mpc {sup -1}. This is in agreement with a previous detection of a suppression in the scalar power [2].

  6. Time history solution program, L225 (TEV126). Volume 1: Engineering and usage

    NASA Technical Reports Server (NTRS)

    Kroll, R. I.; Tornallyay, A.; Clemmons, R. E.

    1979-01-01

    Volume 1 of a two volume document is presented. The usage of the convolution program L225 (TEV 126) is described. The program calculates the time response of a linear system by convoluting the impulsive response function with the time-dependent excitation function. The convolution is performed as a multiplication in the frequency domain. Fast Fourier transform techniques are used to transform the product back into the time domain to obtain response time histories. A brief description of the analysis used is presented.

  7. World History and Geography: Medieval and Early Modern Times. Course Models for the History-Social Science Framework, Grade 7.

    ERIC Educational Resources Information Center

    Prescott, Stephanie, Ed.; And Others

    This document is a response to teachers' requests for practical assistance in implementing California's history-social science framework. The document offers stimulating ideas to enrich the teaching of history and social science, enliven instruction for every student, focus on essential topics, and help make learning more memorable. Experiences…

  8. Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program.

    PubMed

    Boxus, Mathieu; Twizere, Jean-Claude; Legros, Sébastien; Kettmann, Richard; Willems, Luc

    2012-01-01

    The Tax oncoprotein encoded by the human T-cell leukemia virus type 1 plays a pivotal role in viral persistence and pathogenesis. Human T-cell leukemia virus type 1-infected cells proliferate faster than normal lymphocytes, expand through mitotic division, and accumulate genomic lesions. Here, we show that Tax associates with the minichromosome maintenance MCM2-7 helicase complex and localizes to origins of replication. Tax modulates the spatiotemporal program of origin activation and fires supplementary origins at the onset of S phase. Thereby, Tax increases the DNA replication rate, accelerates S phase progression, but also generates a replicative stress characterized by the presence of genomic lesions. Mechanistically, Tax favors p300 recruitment and histone hyperacetylation at late replication domains, advancing their replication timing in early S phase. PMID:22058115

  9. Early inflation to late-time acceleration in f(G) model

    NASA Astrophysics Data System (ADS)

    Dutta, Malay Krishna; Sarkar, Kaushik; Modak, B.

    2016-09-01

    We present some solutions in Friedmann-Lemaître-Robertson-Walker (FLRW) spacetime in the modified theory of gravity with a general Gauss-Bonnet (GB) term f(G) and R2 including an ideal fluid. We present evolution of the universe introducing an ansatz without a prior choice of f(G) in one approach, while in other class of model, the solutions are obtained assuming few simple forms of f(G). Some of the solutions show early inflationary expansion, further in one solution the fluctuation of the deceleration parameter q is evident at the end of inflation. In all cases, late-time transition to accelerating universe at redshift z ˜ 0.7 is realizable.

  10. A smoothing expectation and substitution algorithm for the semiparametric accelerated failure time frailty model.

    PubMed

    Johnson, Lynn M; Strawderman, Robert L

    2012-09-20

    This paper proposes an estimation procedure for the semiparametric accelerated failure time frailty model that combines smoothing with an Expectation and Maximization-like algorithm for estimating equations. The resulting algorithm permits simultaneous estimation of the regression parameter, the baseline cumulative hazard, and the parameter indexing a general frailty distribution. We develop novel moment-based estimators for the frailty parameter, including a generalized method of moments estimator. Standard error estimates for all parameters are easily obtained using a randomly weighted bootstrap procedure. For the commonly used gamma frailty distribution, the proposed algorithm is very easy to implement using widely available numerical methods. Simulation results demonstrate that the algorithm performs very well in this setting. We re-analyz several previously analyzed data sets for illustrative purposes.

  11. On using moving windows in finite element time domain simulation for long accelerator structures

    SciTech Connect

    Lee, L.-Q.; Candel, Arno; Ng, Cho; Ko, Kwok

    2010-12-10

    A finite element moving window technique is developed to simulate the propagation of electromagnetic waves induced by the transit of a charged particle beam inside large and long structures. The window moving along with the beam in the computational domain adopts high-order finite element basis functions through p refinement and/or a high-resolution mesh through h refinement so that a sufficient accuracy is attained with substantially reduced computational costs. Algorithms to transfer discretized fields from one mesh to another, which are the keys to implementing a moving window in a finite element unstructured mesh, are presented. Numerical experiments are carried out using the moving window technique to compute short-range wakefields in long accelerator structures. The results are compared with those obtained from the normal finite element time domain (FETD) method and the advantages of using the moving window technique are discussed.

  12. Control, timing, and data acquisition for the Argonne Wakefield Accelerator (AWA)

    SciTech Connect

    Schoessow, P.; Ho, C.; Power, J.; Chojnacki, E.

    1993-08-01

    The AWA is a new facility primarily designed for wakefield acceleration experiments at the 100 MV/m scale, which incorporates a high current linac and rf photocathode electron source, a low emittance rf electron gun for witness beam generation, and associated beamlines and diagnostics. The control system is based on VME and CA-MAC electronics interfaced to a high performance work-station and provides some distributed processing capability. In addition to the control of linac rf, laser optics, and beamlines, the system is also used for acquisition of video data both from luminescent beam position monitors and from streak camera pulse length diagnostics. Online image feature extraction will permit wakefields to be computed during the course of data taking. The linac timing electronics and its interface to the control system is described.

  13. Three classes of space-time with a uniformly accelerating and nonrotating gravitational source

    NASA Astrophysics Data System (ADS)

    Ishikawa, K.-I.; Miyashita, T.

    1983-11-01

    In his study of Einstein spaces, Petrov (1969) has classified curvature tensors algebraically. The present investigation is concerned with the type-D empty spaces which possess a degenerate principal null vector tangent to expanding and nonrotating null geodesic congruences. These spaces have been represented by the C metric. Ishikawa and Miyashita (1982) have conducted a classification of the type-D empty spaces. In the current study, the physical properties of space-time of the three classes are explored. In a representation of the metric forms of the three classes, use is made of the Eddington-Finkelstein type of null coordinates. It is shown that the considered classes can be interpreted as a gravitational field of a uniformly accelerating source which moves with a velocity which is equal to that of light, or either slower or faster than it.

  14. Real-time dose computation: GPU-accelerated source modeling and superposition/convolution

    SciTech Connect

    Jacques, Robert; Wong, John; Taylor, Russell; McNutt, Todd

    2011-01-15

    } times were 8.3 and 94 s, respectively, on an AMD (Sunnyvale, CA) Opteron 254 (two cores, 2.8 GHz). Conclusions: The authors have completed a comprehensive, GPU-accelerated dose engine in order to provide a substantial performance gain over CPU based implementations. Real-time dose computation is feasible with the accuracy levels of the superposition/convolution algorithm.

  15. Dynamic inversion method based on the time-staggered stereo-modeling scheme and its acceleration

    NASA Astrophysics Data System (ADS)

    Jing, Hao; Yang, Dinghui; Wu, Hao

    2016-09-01

    A set of second-order differential equations describing the space-time behavior of derivatives of displacement with respect to model parameters (i.e. waveform sensitivities) is obtained via taking the derivative of the original wave equations. The dynamic inversion method obtains sensitivities of the seismic displacement field with respect to earth properties directly by solving differential equations for them instead of constructing sensitivities from the displacement field itself. In this study, we have taken a new perspective on the dynamic inversion method and used acceleration approaches to reduce the computational time and memory usage to improve its ability of performing high-resolution imaging. The dynamic inversion method, which can simultaneously use different waves and multi-component observation data, is appropriate for directly inverting elastic parameters, medium density or wave velocities. Full wave-field information is utilized as much as possible at the expense of a larger amount of calculations. To mitigate the computational burden, two ways are proposed to accelerate the method from a computer-implementation point of view. One is source encoding which uses a linear combination of all shots, and the other is to reduce the amount of calculations on forward modeling. We applied a new finite difference method to the dynamic inversion to improve the computational accuracy and speed up the performance. Numerical experiments indicated that the new finite difference method can effectively suppress the numerical dispersion caused by the discretization of wave equations, resulting in enhanced computational efficiency with less memory cost for seismic modeling and inversion based on the full wave equations. We present some inversion results to demonstrate the validity of this method through both checkerboard and Marmousi models. It shows that this method is also convergent even with big deviations for the initial model. Besides, parallel calculations can be

  16. A 181 GOPS AKAZE Accelerator Employing Discrete-Time Cellular Neural Networks for Real-Time Feature Extraction.

    PubMed

    Jiang, Guangli; Liu, Leibo; Zhu, Wenping; Yin, Shouyi; Wei, Shaojun

    2015-01-01

    This paper proposes a real-time feature extraction VLSI architecture for high-resolution images based on the accelerated KAZE algorithm. Firstly, a new system architecture is proposed. It increases the system throughput, provides flexibility in image resolution, and offers trade-offs between speed and scaling robustness. The architecture consists of a two-dimensional pipeline array that fully utilizes computational similarities in octaves. Secondly, a substructure (block-serial discrete-time cellular neural network) that can realize a nonlinear filter is proposed. This structure decreases the memory demand through the removal of data dependency. Thirdly, a hardware-friendly descriptor is introduced in order to overcome the hardware design bottleneck through the polar sample pattern; a simplified method to realize rotation invariance is also presented. Finally, the proposed architecture is designed in TSMC 65 nm CMOS technology. The experimental results show a performance of 127 fps in full HD resolution at 200 MHz frequency. The peak performance reaches 181 GOPS and the throughput is double the speed of other state-of-the-art architectures. PMID:26404305

  17. A 181 GOPS AKAZE Accelerator Employing Discrete-Time Cellular Neural Networks for Real-Time Feature Extraction

    PubMed Central

    Jiang, Guangli; Liu, Leibo; Zhu, Wenping; Yin, Shouyi; Wei, Shaojun

    2015-01-01

    This paper proposes a real-time feature extraction VLSI architecture for high-resolution images based on the accelerated KAZE algorithm. Firstly, a new system architecture is proposed. It increases the system throughput, provides flexibility in image resolution, and offers trade-offs between speed and scaling robustness. The architecture consists of a two-dimensional pipeline array that fully utilizes computational similarities in octaves. Secondly, a substructure (block-serial discrete-time cellular neural network) that can realize a nonlinear filter is proposed. This structure decreases the memory demand through the removal of data dependency. Thirdly, a hardware-friendly descriptor is introduced in order to overcome the hardware design bottleneck through the polar sample pattern; a simplified method to realize rotation invariance is also presented. Finally, the proposed architecture is designed in TSMC 65 nm CMOS technology. The experimental results show a performance of 127 fps in full HD resolution at 200 MHz frequency. The peak performance reaches 181 GOPS and the throughput is double the speed of other state-of-the-art architectures. PMID:26404305

  18. A Bayesian approach to joint analysis of multivariate longitudinal data and parametric accelerated failure time

    PubMed Central

    Luo, Sheng

    2013-01-01

    Impairment caused by Parkinson’s disease (PD) is multidimensional (e.g., sensoria, functions, and cognition) and progressive. Its multidimensional nature precludes a single outcome to measure disease progression. Clinical trials of PD use multiple categorical and continuous longitudinal outcomes to assess the treatment effects on overall improvement. A terminal event such as death or dropout can stop the follow-up process. Moreover, the time to the terminal event may be dependent on the multivariate longitudinal measurements. In this article, we consider a joint random-effects model for the correlated outcomes. A multilevel item response theory model is used for the multivariate longitudinal outcomes and a parametric accelerated failure time model is used for the failure time because of the violation of proportional hazard assumption. These two models are linked via random effects. The Bayesian inference via MCMC is implemented in ‘ BUGS’ language. Our proposed method is evaluated by a simulation study and is applied to DATATOP study, a motivating clinical trial to determine if deprenyl slows the progression of PD. PMID:24009073

  19. A Bayesian approach to joint analysis of multivariate longitudinal data and parametric accelerated failure time.

    PubMed

    Luo, Sheng

    2014-02-20

    Impairment caused by Parkinson's disease (PD) is multidimensional (e.g., sensoria, functions, and cognition) and progressive. Its multidimensional nature precludes a single outcome to measure disease progression. Clinical trials of PD use multiple categorical and continuous longitudinal outcomes to assess the treatment effects on overall improvement. A terminal event such as death or dropout can stop the follow-up process. Moreover, the time to the terminal event may be dependent on the multivariate longitudinal measurements. In this article, we consider a joint random-effects model for the correlated outcomes. A multilevel item response theory model is used for the multivariate longitudinal outcomes and a parametric accelerated failure time model is used for the failure time because of the violation of proportional hazard assumption. These two models are linked via random effects. The Bayesian inference via MCMC is implemented in 'BUGS' language. Our proposed method is evaluated by a simulation study and is applied to DATATOP study, a motivating clinical trial to determine if deprenyl slows the progression of PD. PMID:24009073

  20. The L(1/2) regularization approach for survival analysis in the accelerated failure time model.

    PubMed

    Chai, Hua; Liang, Yong; Liu, Xiao-Ying

    2015-09-01

    The analysis of high-dimensional and low-sample size microarray data for survival analysis of cancer patients is an important problem. It is a huge challenge to select the significantly relevant bio-marks from microarray gene expression datasets, in which the number of genes is far more than the size of samples. In this article, we develop a robust prediction approach for survival time of patient by a L(1/2) regularization estimator with the accelerated failure time (AFT) model. The L(1/2) regularization could be seen as a typical delegate of L(q)(0time of patient based on a set of clinical prognostic factors and gene signatures.

  1. Using precise word timing information improves decoding accuracy in a multiband-accelerated multimodal reading experiment.

    PubMed

    Vu, An T; Phillips, Jeffrey S; Kay, Kendrick; Phillips, Matthew E; Johnson, Matthew R; Shinkareva, Svetlana V; Tubridy, Shannon; Millin, Rachel; Grossman, Murray; Gureckis, Todd; Bhattacharyya, Rajan; Yacoub, Essa

    2016-01-01

    The blood-oxygen-level-dependent (BOLD) signal measured in functional magnetic resonance imaging (fMRI) experiments is generally regarded as sluggish and poorly suited for probing neural function at the rapid timescales involved in sentence comprehension. However, recent studies have shown the value of acquiring data with very short repetition times (TRs), not merely in terms of improvements in contrast to noise ratio (CNR) through averaging, but also in terms of additional fine-grained temporal information. Using multiband-accelerated fMRI, we achieved whole-brain scans at 3-mm resolution with a TR of just 500 ms at both 3T and 7T field strengths. By taking advantage of word timing information, we found that word decoding accuracy across two separate sets of scan sessions improved significantly, with better overall performance at 7T than at 3T. The effect of TR was also investigated; we found that substantial word timing information can be extracted using fast TRs, with diminishing benefits beyond TRs of 1000 ms. PMID:27686111

  2. Using precise word timing information improves decoding accuracy in a multiband-accelerated multimodal reading experiment.

    PubMed

    Vu, An T; Phillips, Jeffrey S; Kay, Kendrick; Phillips, Matthew E; Johnson, Matthew R; Shinkareva, Svetlana V; Tubridy, Shannon; Millin, Rachel; Grossman, Murray; Gureckis, Todd; Bhattacharyya, Rajan; Yacoub, Essa

    2016-01-01

    The blood-oxygen-level-dependent (BOLD) signal measured in functional magnetic resonance imaging (fMRI) experiments is generally regarded as sluggish and poorly suited for probing neural function at the rapid timescales involved in sentence comprehension. However, recent studies have shown the value of acquiring data with very short repetition times (TRs), not merely in terms of improvements in contrast to noise ratio (CNR) through averaging, but also in terms of additional fine-grained temporal information. Using multiband-accelerated fMRI, we achieved whole-brain scans at 3-mm resolution with a TR of just 500 ms at both 3T and 7T field strengths. By taking advantage of word timing information, we found that word decoding accuracy across two separate sets of scan sessions improved significantly, with better overall performance at 7T than at 3T. The effect of TR was also investigated; we found that substantial word timing information can be extracted using fast TRs, with diminishing benefits beyond TRs of 1000 ms.

  3. Life history as a constraint on plasticity: developmental timing is correlated with phenotypic variation in birds.

    PubMed

    Snell-Rood, E C; Swanson, E M; Young, R L

    2015-10-01

    Understanding why organisms vary in developmental plasticity has implications for predicting population responses to changing environments and the maintenance of intraspecific variation. The epiphenotype hypothesis posits that the timing of development can constrain plasticity-the earlier alternate phenotypes begin to develop, the greater the difference that can result amongst the final traits. This research extends this idea by considering how life history timing shapes the opportunity for the environment to influence trait development. We test the prediction that the earlier an individual begins to actively interact with and explore their environment, the greater the opportunity for plasticity and thus variation in foraging traits. This research focuses on life history variation across four groups of birds using museum specimens and measurements from the literature. We reasoned that greater phenotypic plasticity, through either environmental effects or genotype-by-environment interactions in development, would be manifest in larger trait ranges (bills and tarsi) within species. Among shorebirds and ducks, we found that species with relatively shorter incubation times tended to show greater phenotypic variation. Across warblers and sparrows, we found little support linking timing of flight and trait variation. Overall, our results also suggest a pattern between body size and trait variation, consistent with constraints on egg size that might result in larger species having more environmental influences on development. Taken together, our results provide some support for the hypothesis that variation in life histories affects how the environment shapes development, through either the expression of plasticity or the release of cryptic genetic variation.

  4. Primate enamel evinces long period biological timing and regulation of life history.

    PubMed

    Bromage, Timothy G; Hogg, Russell T; Lacruz, Rodrigo S; Hou, Chen

    2012-07-21

    The factor(s) regulating the combination of traits that define the overall life history matrix of mammalian species, comprising attributes such as brain and body weight, age at sexual maturity, lifespan and others, remains a complete mystery. The principal objectives of the present research are (1) to provide evidence for a key variable effecting life history integration and (2) to provide a model for how one would go about investigating the metabolic mechanisms responsible for this rhythm. We suggest here that a biological rhythm with a period greater than the circadian rhythm is responsible for observed variation in primate life history. Evidence for this rhythm derives from studies of tooth enamel formation. Enamel contains an enigmatic periodicity in its microstructure called the striae of Retzius, which develops at species specific intervals in units of whole days. We refer to this enamel rhythm as the repeat interval (RI). For primates, we identify statistically significant relationships between RI and all common life history traits. Importantly, RI also correlates with basal and specific metabolic rates. With the exception of estrous cyclicity, all relationships share a dependence upon body mass. This dependence on body mass informs us that some aspect of metabolism is responsible for periodic energy allocations at RI timescales, regulating cell proliferation rates and growth, thus controlling the pace, patterning, and co-variation of life history traits. Estrous cyclicity relates to the long period rhythm in a body mass-independent manner. The mass-dependency and -independency of life history relationships with RI periodicity align with hypothalamic-mediated neurosecretory anterior and posterior pituitary outputs. We term this period the Havers-Halberg Oscillation (HHO), in reference to Clopton Havers, a 17th Century hard tissue anatomist, and Franz Halberg, a long-time explorer of long-period rhythms. We propose a mathematical model that may help elucidate

  5. Wavelet Transform Based Higher Order Statistical Analysis of Wind and Wave Time Histories

    NASA Astrophysics Data System (ADS)

    Habib Huseni, Gulamhusenwala; Balaji, Ramakrishnan

    2016-06-01

    Wind, blowing on the surface of the ocean, imparts the energy to generate the waves. Understanding the wind-wave interactions is essential for an oceanographer. This study involves higher order spectral analyses of wind speeds and significant wave height time histories, extracted from European Centre for Medium-Range Weather Forecast database at an offshore location off Mumbai coast, through continuous wavelet transform. The time histories were divided by the seasons; pre-monsoon, monsoon, post-monsoon and winter and the analysis were carried out to the individual data sets, to assess the effect of various seasons on the wind-wave interactions. The analysis revealed that the frequency coupling of wind speeds and wave heights of various seasons. The details of data, analysing technique and results are presented in this paper.

  6. An exhumation history of continents over billion-year time scales.

    PubMed

    Blackburn, Terrence J; Bowring, Samuel A; Perron, J Taylor; Mahan, Kevin H; Dudas, Francis O; Barnhart, Katherine R

    2012-01-01

    The continental lithosphere contains the oldest and most stable structures on Earth, where fragments of ancient material have eluded destruction by tectonic and surface processes operating over billions of years. Although present-day erosion of these remnants is slow, a record of how they have uplifted, eroded, and cooled over Earth's history can provide insight into the physical properties of the continents and the forces operating to exhume them over geologic time. We constructed a continuous record of ancient lithosphere cooling with the use of uranium-lead (U-Pb) thermochronology on volcanically exhumed lower crustal fragments. Combining these measurements with thermal and Pb-diffusion models constrains the range of possible erosion histories. Measured U-Pb data are consistent with extremely low erosion rates persisting over time scales approaching the age of the continents themselves.

  7. Modified gravity à la Galileon: Late time cosmic acceleration and observational constraints

    NASA Astrophysics Data System (ADS)

    Ali, Amna; Gannouji, Radouane; Sami, M.

    2010-11-01

    In this paper we examine the cosmological consequences of fourth order Galileon gravity. We carry out detailed investigations of the underlying dynamics and demonstrate the stability of one de Sitter phase. The stable de Sitter phase contains a Galileon field π which is an increasing function of time (π˙>0). Using the required suppression of the fifth force, supernovae, Baryon acoustic oscillations, and CMB data, we constrain parameters of the model. We find that the π matter coupling parameter β is constrained to small numerical values such that β<0.02. We also show that the parameters of the third and fourth order in the action (c3,c4) are not independent and with reasonable assumptions, we obtain constraints on them. We investigate the growth history of the model and find that the subhorizon approximation is not allowed for this model. We demonstrate strong scale dependence of linear perturbations in the fourth order Galileon gravity.

  8. Modified gravity a la Galileon: Late time cosmic acceleration and observational constraints

    SciTech Connect

    Ali, Amna; Sami, M.; Gannouji, Radouane

    2010-11-15

    In this paper we examine the cosmological consequences of fourth order Galileon gravity. We carry out detailed investigations of the underlying dynamics and demonstrate the stability of one de Sitter phase. The stable de Sitter phase contains a Galileon field {pi} which is an increasing function of time ({pi}>0). Using the required suppression of the fifth force, supernovae, Baryon acoustic oscillations, and CMB data, we constrain parameters of the model. We find that the {pi} matter coupling parameter {beta} is constrained to small numerical values such that {beta}<0.02. We also show that the parameters of the third and fourth order in the action (c{sub 3},c{sub 4}) are not independent and with reasonable assumptions, we obtain constraints on them. We investigate the growth history of the model and find that the subhorizon approximation is not allowed for this model. We demonstrate strong scale dependence of linear perturbations in the fourth order Galileon gravity.

  9. TIME-DEPENDENT DIFFUSIVE SHOCK ACCELERATION IN SLOW SUPERNOVA REMNANT SHOCKS

    SciTech Connect

    Tang, Xiaping; Chevalier, Roger A. E-mail: rac5x@virginia.edu

    2015-02-20

    Recent gamma-ray observations show that middle-aged supernova remnants (SNRs) interacting with molecular clouds can be sources of both GeV and TeV emission. Models involving reacceleration of preexisting cosmic rays (CRs) in the ambient medium and direct interaction between SNR and molecular clouds have been proposed to explain the observed gamma-ray emission. For the reacceleration process, standard diffusive shock acceleration (DSA) theory in the test particle limit produces a steady-state particle spectrum that is too flat compared to observations, which suggests that the high-energy part of the observed spectrum has not yet reached a steady state. We derive a time-dependent DSA solution in the test particle limit for situations involving reacceleration of preexisting CRs in the preshock medium. Simple estimates with our time-dependent DSA solution plus a molecular cloud interaction model can reproduce the overall shape of the spectra of IC 443 and W44 from GeV to TeV energies through pure π{sup 0}-decay emission. We allow for a power-law momentum dependence of the diffusion coefficient, finding that a power-law index of 0.5 is favored.

  10. Development of a subway operation incident delay model using accelerated failure time approaches.

    PubMed

    Weng, Jinxian; Zheng, Yang; Yan, Xuedong; Meng, Qiang

    2014-12-01

    This study aims to develop a subway operational incident delay model using the parametric accelerated time failure (AFT) approach. Six parametric AFT models including the log-logistic, lognormal and Weibull models, with fixed and random parameters are built based on the Hong Kong subway operation incident data from 2005 to 2012, respectively. In addition, the Weibull model with gamma heterogeneity is also considered to compare the model performance. The goodness-of-fit test results show that the log-logistic AFT model with random parameters is most suitable for estimating the subway incident delay. First, the results show that a longer subway operation incident delay is highly correlated with the following factors: power cable failure, signal cable failure, turnout communication disruption and crashes involving a casualty. Vehicle failure makes the least impact on the increment of subway operation incident delay. According to these results, several possible measures, such as the use of short-distance and wireless communication technology (e.g., Wifi and Zigbee) are suggested to shorten the delay caused by subway operation incidents. Finally, the temporal transferability test results show that the developed log-logistic AFT model with random parameters is stable over time. PMID:25171521

  11. Multigrid Acceleration of Time-Accurate DNS of Compressible Turbulent Flow

    NASA Technical Reports Server (NTRS)

    Broeze, Jan; Geurts, Bernard; Kuerten, Hans; Streng, Martin

    1996-01-01

    An efficient scheme for the direct numerical simulation of 3D transitional and developed turbulent flow is presented. Explicit and implicit time integration schemes for the compressible Navier-Stokes equations are compared. The nonlinear system resulting from the implicit time discretization is solved with an iterative method and accelerated by the application of a multigrid technique. Since we use central spatial discretizations and no artificial dissipation is added to the equations, the smoothing method is less effective than in the more traditional use of multigrid in steady-state calculations. Therefore, a special prolongation method is needed in order to obtain an effective multigrid method. This simulation scheme was studied in detail for compressible flow over a flat plate. In the laminar regime and in the first stages of turbulent flow the implicit method provides a speed-up of a factor 2 relative to the explicit method on a relatively coarse grid. At increased resolution this speed-up is enhanced correspondingly.

  12. Extracting Concrete Thermal Characteristics from Temperature Time History of RC Column Exposed to Standard Fire

    PubMed Central

    2014-01-01

    A numerical method to identify thermal conductivity from time history of one-dimensional temperature variations in thermal unsteady-state is proposed. The numerical method considers the change of specific heat and thermal conductivity with respect to temperature. Fire test of reinforced concrete (RC) columns was conducted using a standard fire to obtain time history of temperature variations in the column section. A thermal equilibrium model in unsteady-state condition was developed. The thermal conductivity of concrete was then determined by optimizing the numerical solution of the model to meet the observed time history of temperature variations. The determined thermal conductivity with respect to temperature was then verified against standard thermal conductivity measurements of concrete bricks. It is concluded that the proposed method can be used to conservatively estimate thermal conductivity of concrete for design purpose. Finally, the thermal radiation properties of concrete for the RC column were estimated from the thermal equilibrium at the surface of the column. The radiant heat transfer ratio of concrete representing absorptivity to emissivity ratio of concrete during fire was evaluated and is suggested as a concrete criterion that can be used in fire safety assessment. PMID:25180197

  13. Extracting concrete thermal characteristics from temperature time history of RC column exposed to standard fire.

    PubMed

    Kim, Jung J; Youm, Kwang-Soo; Reda Taha, Mahmoud M

    2014-01-01

    A numerical method to identify thermal conductivity from time history of one-dimensional temperature variations in thermal unsteady-state is proposed. The numerical method considers the change of specific heat and thermal conductivity with respect to temperature. Fire test of reinforced concrete (RC) columns was conducted using a standard fire to obtain time history of temperature variations in the column section. A thermal equilibrium model in unsteady-state condition was developed. The thermal conductivity of concrete was then determined by optimizing the numerical solution of the model to meet the observed time history of temperature variations. The determined thermal conductivity with respect to temperature was then verified against standard thermal conductivity measurements of concrete bricks. It is concluded that the proposed method can be used to conservatively estimate thermal conductivity of concrete for design purpose. Finally, the thermal radiation properties of concrete for the RC column were estimated from the thermal equilibrium at the surface of the column. The radiant heat transfer ratio of concrete representing absorptivity to emissivity ratio of concrete during fire was evaluated and is suggested as a concrete criterion that can be used in fire safety assessment.

  14. Mediation Analysis with Survival Outcomes: Accelerated Failure Time vs. Proportional Hazards Models

    PubMed Central

    Gelfand, Lois A.; MacKinnon, David P.; DeRubeis, Robert J.; Baraldi, Amanda N.

    2016-01-01

    Objective: Survival time is an important type of outcome variable in treatment research. Currently, limited guidance is available regarding performing mediation analyses with survival outcomes, which generally do not have normally distributed errors, and contain unobserved (censored) events. We present considerations for choosing an approach, using a comparison of semi-parametric proportional hazards (PH) and fully parametric accelerated failure time (AFT) approaches for illustration. Method: We compare PH and AFT models and procedures in their integration into mediation models and review their ability to produce coefficients that estimate causal effects. Using simulation studies modeling Weibull-distributed survival times, we compare statistical properties of mediation analyses incorporating PH and AFT approaches (employing SAS procedures PHREG and LIFEREG, respectively) under varied data conditions, some including censoring. A simulated data set illustrates the findings. Results: AFT models integrate more easily than PH models into mediation models. Furthermore, mediation analyses incorporating LIFEREG produce coefficients that can estimate causal effects, and demonstrate superior statistical properties. Censoring introduces bias in the coefficient estimate representing the treatment effect on outcome—underestimation in LIFEREG, and overestimation in PHREG. With LIFEREG, this bias can be addressed using an alternative estimate obtained from combining other coefficients, whereas this is not possible with PHREG. Conclusions: When Weibull assumptions are not violated, there are compelling advantages to using LIFEREG over PHREG for mediation analyses involving survival-time outcomes. Irrespective of the procedures used, the interpretation of coefficients, effects of censoring on coefficient estimates, and statistical properties should be taken into account when reporting results. PMID:27065906

  15. Manual for Getdata Version 3.1: a FORTRAN Utility Program for Time History Data

    NASA Technical Reports Server (NTRS)

    Maine, Richard E.

    1987-01-01

    This report documents version 3.1 of the GetData computer program. GetData is a utility program for manipulating files of time history data, i.e., data giving the values of parameters as functions of time. The most fundamental capability of GetData is extracting selected signals and time segments from an input file and writing the selected data to an output file. Other capabilities include converting file formats, merging data from several input files, time skewing, interpolating to common output times, and generating calculated output signals as functions of the input signals. This report also documents the interface standards for the subroutines used by GetData to read and write the time history files. All interface to the data files is through these subroutines, keeping the main body of GetData independent of the precise details of the file formats. Different file formats can be supported by changes restricted to these subroutines. Other computer programs conforming to the interface standards can call the same subroutines to read and write files in compatible formats.

  16. Real-time particle-detection probabilities in accelerated macroscopic detectors

    NASA Astrophysics Data System (ADS)

    Anastopoulos, Charis; Savvidou, Ntina

    2015-01-01

    We construct the detection rate for particle detectors moving along non-inertial trajectories and interacting with quantum fields. The detectors described here are characterized by the presence of records of observation throughout their history, so that the detection rate corresponds to directly measurable quantities. This is in contrast to past treatments of detectors, which actually refer to probes, i.e., microscopic systems from which we extract information only after their interaction has been completed. Our treatment incorporates the irreversibility due to the creation of macroscopic records of observation. The key result is a real-time description of particle detection and a rigorously defined time-local probability density function (PDF). The PDF depends on the scale of the temporal coarse-graining that is necessary for the formation of a macroscopic record. The evaluation of the PDF for Unruh-DeWitt detectors along different types of trajectory shows that only paths with at least one characteristic time-scale much smaller than lead to appreciable particle detection. Our approach allows for averaging over fast motions and thus predicts a constant detection rate for all fast periodic motions.

  17. Femtosecond timing distribution and control for next generation accelerators and light sources

    SciTech Connect

    Chen, Li -Jin

    2014-03-31

    Femtosecond Timing Distribution At LCLS Free-electron-lasers (FEL) have the capability of producing high photon flux from the IR to the hard x-ray wavelength range and to emit femtosecond and eventually even attosecond pulses. This makes them an ideal tool for fundamental as well as applied re-search. Timing precision at the Stanford Linear Coherent Light Source (LCLS) between the x-ray FEL (XFEL) and ultrafast optical lasers is currently no better than 100 fs RMS. Ideally this precision should be much better and could be limited only by the x-ray pulse duration, which can be as short as a few femtoseconds. An increasing variety of science problems involving electron and nuclear dynamics in chemical and material systems will become accessible as the timing improves to a few femtoseconds. Advanced methods of electron beam conditioning or pulse injection could allow the FEL to achieve pulse durations less than one femtosecond. The objective of the work described in this proposal is to set up an optical timing distribution system based on mode locked Erbium doped fiber lasers at LCLS facility to improve the timing precision in the facility and allow time stamping with a 10 fs precision. The primary commercial applications for optical timing distributions systems are seen in the worldwide accelerator facilities and next generation light sources community. It is reasonable to expect that at least three major XFELs will be built in the next decade. In addition there will be up to 10 smaller machines, such as FERMI in Italy and Maxlab in Sweden, plus the market for upgrading already existing facilities like Jefferson Lab. The total market is estimated to be on the order of a 100 Million US Dollars. The company owns the exclusive rights to the IP covering the technology enabling sub-10 fs synchronization systems. Testing this technology, which has set records in a lab environment, at LCLS, hence in a real world scenario, is an important corner stone of bringing the

  18. The Effects of Art History-Enriched Art Therapy on Anxiety, Time on Task, and Art Product Quality.

    ERIC Educational Resources Information Center

    Miller, Carol L.

    1993-01-01

    Investigated effects of art history enrichment of art therapy task on anxiety, time on task, and art product quality among 13 chronic adult psychiatric day hospital patients. Results indicated art history enrichment task reduced anxiety and increased time on task. Art organization level tended toward significant increase compared with control…

  19. Exploring the History of Time in an Integrated System: the Ramifications for Water

    NASA Astrophysics Data System (ADS)

    Green, M. B.; Adams, L. E.; Allen, T. L.; Arrigo, J. S.; Bain, D. J.; Bray, E. N.; Duncan, J. M.; Hermans, C. M.; Pastore, C.; Schlosser, C. A.; Vorosmarty, C. J.; Witherell, B. B.; Wollheim, W. M.; Wreschnig, A. J.

    2009-12-01

    Characteristic time scales are useful and simple descriptors of geophysical and socio-economic system dynamics. Focusing on the integrative nature of the hydrologic cycle, new insights into system couplings can be gained by compiling characteristic time scales of important processes driving these systems. There are many examples of changing characteristic time scales. Human life expectancy has increased over the recent history of medical advancement. The transport time of goods has decreased with the progression from horse to rail to car to plane. The transport time of information changed with the progression from letter to telegraph to telephone to networked computing. Soil residence time (pedogenesis to estuary deposition) has been influenced by changing agricultural technology, urbanization, and forest practices. Surface water residence times have varied as beaver dams have disappeared and been replaced with modern reservoirs, flood control works, and channelization. These dynamics raise the question of how these types of time scales interact with each other to form integrated Earth system dynamics? Here we explore the coupling of geophysical and socio-economic systems in the northeast United States over the 1600 to 2010 period by examining characteristic time scales. This visualization of many time scales serves as an exploratory analysis, producing new hypotheses about how the integrated system dynamics have evolved over the last 400 years. Specifically, exponential population growth and the evolving strategies to maintain that population appears as fundamental to many of the time scales.

  20. History of psychological knowledge in Brazilian culture: Weaving threads on the loom of time.

    PubMed

    Massimi, Marina; Gontijo, Sandro R

    2015-05-01

    After a brief presentation of the research program on the "history of psychological knowledge in the ambit of cultural history," this article addresses 2 issues that we consider particularly important from the methodological point of view: the notion of multiple temporalities (regimes of historicity) and of complexity as characteristics of the contexture of Brazilian culture. It will be shown how both require specific attention from the researcher, because the process of incorporation of psychology in Brazil over time is complex and articulated according to various regimes of historicity that intersect and interpenetrate each other, without being exclusive. Our approach will be exemplified by the concept of memory, showing how this can be grasped in its constitution in Brazilian culture, which is composed of several sedimented layers according to different temporalities.

  1. Real time and accelerated stability studies of Tetanus toxoid manufactured in public sector facilities of Pakistan.

    PubMed

    Parveen, Ghazala; Hussain, Shahzad; Malik, Farnaz; Begum, Anwar; Mahmood, Sidra; Raza, Naeem

    2013-11-01

    Tetanus is an acute illness represented by comprehensive increased inflexibility and spastic spasms of skeletal muscles. The poor quality tetanus toxoid vaccine can raise the prevalence of neonatal tetanus. WHO has taken numerous steps to assist national regulatory authorities and vaccine manufacturers to ensure its quality and efficacy. It has formulated international principles for stability evaluation of each vaccine, which are available in the form of recommendations and guidelines. The aim of present study was to ensure the stability of tetanus vaccines produced by National Institute of Health, Islamabad, Pakistan by employing standardized methods to ensure constancy of tetanus toxoid at elevated temperature, if during storage/transportation cold chain may not be maintained in hot weather. A total of three batches filled during full-scale production were tested. All Stability studies determination were performed on final products stored at 2-8°C and elevated temperatures in conformance with the ICH Guideline of Stability Testing of Biological Products. These studies gave comparison between real time shelf-life stability and accelerated stability studies. The findings indicate long﷓term thermo stability and prove that this tetanus vaccine can remain efficient under setting of routine use when suggested measures for storage and handling are followed in true spirit.

  2. Generalized Radar 4-COORDINATES and Equal-Time Cauchy Surfaces for Arbitrary Accelerated Observers

    NASA Astrophysics Data System (ADS)

    Alba, David; Lusanna, Luca

    All existing 4-coordinate systems centered on the world-line of an accelerated observer are only locally defined, as for Fermi coordinates both in special and general relativity. As a consequence, it is not known how non-inertial observers can build equal-time surfaces which (a) correspond to a conventional observer-dependent definition of synchronization of distant clocks, and (b) are good Cauchy surfaces for Maxwell equations. Another type of coordinate singularities generating the same problems are those connected to the relativistic rotating coordinate systems used in the treatment of the rotating disk and the Sagnac effect. We show that the use of Hamiltonian methods based on 3+1 splittings of space-time allows one to define as many observer-dependent globally defined radar 4-coordinate systems as nice foliations of space-time with space-like hyper-surfaces admissible according to Møller (for instance, only the differentially rotating relativistic coordinate system, but not the rigidly rotating ones of non-relativistic physics, are allowed). All these conventional notions of an instantaneous 3-space for an arbitrary observer can be empirically defined by introducing generalizations of the Einstein ½ convention for clock synchronization in inertial frames. Each admissible 3+1 splitting has two naturally associated congruences of time-like observers: as a consequence every 3+1 splitting gives rise to non-rigid non-inertial frames centered on any one of these observers. Only for Eulerian observers are the simultaneity leaves orthogonal to the observer world-line. When there is a Lagrangian description of an isolated relativistic system, its reformulation as a parametrized Minkowski theory allows one to show that all the admissible synchronization conventions are gauge equivalent, as also happens in the canonical metric and tetrad gravity, where, however, the chrono-geometrical structure of space-time is dynamically determined. The framework developed in this

  3. Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer.

    PubMed

    Tamaki, Yukihisa; Hieda, Yoko; Yoshida, Rika; Yoshizako, Takeshi; Fuchiwaki, Takafumi; Aoi, Noriaki; Sekihara, Kazumasa; Kitajima, Kazuhiro; Kawauchi, Hideyuki; Kitagaki, Hajime; Sasaki, Ryohei; Inomata, Taisuke

    2015-11-01

    Accelerated hyperfractionated radiotherapy was performed as treatment for patients with T1 glottic cancer, and its utility was evaluated based on treatment outcomes and adverse effects. Fifty-eight men who had undergone radiotherapy were retrospectively reviewed. Tumor classification was Tis in 4 patients, T1a in 38, and T1b in 16. Histological examination revealed squamous cell carcinoma in 55 patients. Travel time from home to hospital was 0-1 hour for 24 patients, 1-2 hours for 9, and >2 hours for 25. Laser vaporization was performed prior to radiotherapy in 38 patients, and 19 patients received concurrent chemotherapy with an agent such as S-1. Patients were irradiated twice daily using an irradiation container. Most patients received a dose of 1.5 Gy/fraction up to a total of 60 Gy. The median overall treatment time was 30 days, with a median observation period of 59.6 months. A complete response was observed in all patients. The 5-year overall survival, disease-free survival, and local control rates were 97.2%, 93.2%, and 97.8%, respectively. Although grade 3 pharyngeal mucositis was observed in 2 patients, there were no other grade 3 or higher acute adverse events. As late toxicity, grade 2 laryngeal edema and grade 1 laryngeal hemorrhage were observed in 1 patient each, but no serious events such as laryngeal necrosis or laryngeal stenosis were observed. In conclusion, this treatment method brings excellent outcome and will substantially reduce the treatment duration among patients who need to stay at nearby hotels while undergoing treatment at hospitals in rural areas. PMID:26663937

  4. Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 glottic cancer

    PubMed Central

    Tamaki, Yukihisa; Hieda, Yoko; Yoshida, Rika; Yoshizako, Takeshi; Fuchiwaki, Takafumi; Aoi, Noriaki; Sekihara, Kazumasa; Kitajima, Kazuhiro; Kawauchi, Hideyuki; Kitagaki, Hajime; Sasaki, Ryohei; Inomata, Taisuke

    2015-01-01

    ABSTRACT Accelerated hyperfractionated radiotherapy was performed as treatment for patients with T1 glottic cancer, and its utility was evaluated based on treatment outcomes and adverse effects. Fifty-eight men who had undergone radiotherapy were retrospectively reviewed. Tumor classification was Tis in 4 patients, T1a in 38, and T1b in 16. Histological examination revealed squamous cell carcinoma in 55 patients. Travel time from home to hospital was 0–1 hour for 24 patients, 1–2 hours for 9, and >2 hours for 25. Laser vaporization was performed prior to radiotherapy in 38 patients, and 19 patients received concurrent chemotherapy with an agent such as S-1. Patients were irradiated twice daily using an irradiation container. Most patients received a dose of 1.5 Gy/fraction up to a total of 60 Gy. The median overall treatment time was 30 days, with a median observation period of 59.6 months. A complete response was observed in all patients. The 5-year overall survival, disease-free survival, and local control rates were 97.2%, 93.2%, and 97.8%, respectively. Although grade 3 pharyngeal mucositis was observed in 2 patients, there were no other grade 3 or higher acute adverse events. As late toxicity, grade 2 laryngeal edema and grade 1 laryngeal hemorrhage were observed in 1 patient each, but no serious events such as laryngeal necrosis or laryngeal stenosis were observed. In conclusion, this treatment method brings excellent outcome and will substantially reduce the treatment duration among patients who need to stay at nearby hotels while undergoing treatment at hospitals in rural areas. PMID:26663937

  5. Time history of the Martian dynamo from crater magnetic field analysis

    NASA Astrophysics Data System (ADS)

    Lillis, Robert J.; Robbins, Stuart; Manga, Michael; Halekas, Jasper S.; Frey, Herbert V.

    2013-07-01

    impacts simultaneously reset both the surface age and the magnetization of the entire depth of crust over areas comparable to the final size of the resulting craters. These properties make large impact craters (>300 km in diameter) ideal "magnetic markers" for constraining the history of the Martian core dynamo. However, the relationship between crustal magnetization and magnetic field measured in orbit is nonunique, making the measured magnetic field signature of an impact crater only a proxy for the magnetization (or lack thereof) below. Using Monte Carlo Fourier domain modeling of subsurface magnetization, we calculate probability distributions of the magnetic field signatures of partially and completely demagnetized craters. We compare these distributions to measured magnetic field signatures of 41 old impact craters on Mars larger than 300 km in diameter and calculate probabilities of their magnetization state. We compare these probabilities to cratering densities and absolute model ages and in this manner arrive at a robust time history of Martian large-crater magnetization and hence of the Martian dynamo. We conclude that the most likely scenario was a Mars dynamo active when the oldest detectable basins formed, ceasing before the Hellas and Utopia impacts, between 4.0 and 4.1 Ga (in model age) and not thereafter restarting. The Mars atmosphere was thereafter exposed directly to erosion by the solar wind, significantly altering the path of climate evolution. Further improvements to the history of the Martian dynamo will require better crater age estimates and lower altitude magnetic field data.

  6. Time history of the Martian dynamo from crater magnetic field analysis

    NASA Astrophysics Data System (ADS)

    Lillis, R. J.; Robbins, S. J.; Manga, M.; Halekas, J. S.; Frey, H.

    2013-12-01

    Large impacts simultaneously reset both the surface age and the magnetization of the entire depth of crust over areas comparable to the final size of the resulting craters. These properties make large impact craters (>300 km in diameter) ideal 'magnetic markers' for constraining the history of the Martian core dynamo. However the relationship between crustal magnetization and magnetic field measured in orbit is non-unique, making the measured magnetic field signature of an impact crater only a proxy for the magnetization (or lack thereof) below. Using Monte Carlo Fourier domain modeling of subsurface magnetization, we calculate probability distributions of the magnetic field signatures of partially and completely demagnetized craters. We compare these distributions to measured magnetic field signatures of 41 old impact craters on Mars larger than 300 km in diameter and calculate probabilities of their magnetization state. We compare these probabilities to cratering densities and absolute model ages and in this manner arrive at a robust time-history of Martian large crater magnetization and hence of the Martian dynamo. We conclude that the most likely scenario was a Mars dynamo active when the oldest detectable basins formed, ceasing before the Hellas and Utopia impacts, between 4.0 and 4.1 Ga (in model age) and not thereafter restarting. The Mars atmosphere was thereafter exposed directly to erosion by the solar wind, significantly altering the path of climate evolution. Further improvements to the history of the Martian dynamo will require better crater age estimates and lower altitude magnetic field data.

  7. The history of bronchial asthma from the ancient times till the Middle Ages.

    PubMed

    Cserháti, E

    2004-01-01

    The aim of the paper is to give an overview of the knowledge on asthma through the history of mankind. The text begins with ancient China and it is finished with the medicine of Middle Age. During this time, a lot of theories came and this appeared about the etiology and therapy of the disease. The paper is giving a short description of the changing medical views during this very long period including China, Egypt Greco-roman period, Mesopotamia, the Hebrews, the physicians of India, the pre-Columbian medicine in the America and the Arabic world, and partly the European medicine of the Middle Ages.

  8. History of ancient copper smelting pollution during Roman and Medieval times recorded in Greenland ice

    SciTech Connect

    Hong, Sungmin; Candelone, J.P.; Patterson, C.C.; Boultron, C.F.

    1996-04-12

    Determination of copper concentrations in Greenland ice dated from seven millennia ago to the present showed values exceeding natural levels, beginning about 2500 years ago. This early large-scale pollution of the atmosphere of the Northern Hemisphere is attributed to emissions from the crude, highly polluting smelting technologies used for copper production during Roman and medieval times, especially in Europe and China. This study opens the way to a quantitative assessment of the history of early metal production, which was instrumental in the development of human cultures during ancient eras. 27 refs., 1 fig., 2 tabs.

  9. The history of bronchial asthma from the ancient times till the Middle Ages.

    PubMed

    Cserháti, E

    2004-01-01

    The aim of the paper is to give an overview of the knowledge on asthma through the history of mankind. The text begins with ancient China and it is finished with the medicine of Middle Age. During this time, a lot of theories came and this appeared about the etiology and therapy of the disease. The paper is giving a short description of the changing medical views during this very long period including China, Egypt Greco-roman period, Mesopotamia, the Hebrews, the physicians of India, the pre-Columbian medicine in the America and the Arabic world, and partly the European medicine of the Middle Ages. PMID:16438118

  10. The time history module; A FASTBUS-interfaced logical analyzer for detector monitoring and other applications

    SciTech Connect

    Galeotti, S.; Morsani, F.; Passuello, D.; Salvadori, P. )

    1990-12-01

    A first prototype of a FASTBUS-interfaced logical analyzer module usefully employable in detector and/or trigger system monitoring is described. Four of these time history modules (THM's) have been successfully utilized in the NA31 experiment at CERN from 1985-1989, principally to control the purity of the accepted events. These THM's have a built-in interface to the trigger system (based on finite state machine technique), a double input buffer, and a 20-MHz sampling clock. The best features of the THM are the glitch capture, the fully programmable sampling time interval, the fast double-input buffer, the separate readout buffer, the data compression capability, the high time resolution, the FASTBUS block-reading, and the easy and flexible triggering. Technological improvements are now possible in storage capacity, speed, programmability, and power dissipation.

  11. Examining the limits of time reweighting and Kramers' rate theory to obtain correct kinetics from accelerated molecular dynamics.

    PubMed

    Xin, Yao; Doshi, Urmi; Hamelberg, Donald

    2010-06-14

    Accelerated molecular dynamics simulations are routinely being used to recover the correct canonical probability distributions corresponding to the original potential energy landscape of biomolecular systems. However, the limits of time reweighting, based on transition state theory, in obtaining true kinetic rates from accelerated molecular dynamics for biomolecular systems are less obvious. Here, we investigate this issue by studying the kinetics of cis-trans isomerization of peptidic omega bond by accelerated molecular dynamics. We find that time reweighting is valid for obtaining true kinetics when the original potential is not altered at the transition state regions, as expected. When the original potential landscape is modified such that the applied boost potential alters the transition state regions, time reweighting fails to reproduce correct kinetics and the reweighted rate is much slower than the true rate. By adopting the overdamped limit of Kramers' rate theory, we are successful in recovering correct kinetics irrespective of whether or not the transition state regions are modified. Furthermore, we tested the validity of the acceleration weight factor from the path integral formalism for obtaining the correct kinetics of cis-trans isomerization. It was found that this formulation of the weight factor is not suitable for long time scale processes such as cis-trans isomerization with high energy barriers.

  12. A simple approach to estimate earthquake magnitude from the arrival time of the peak acceleration amplitude

    NASA Astrophysics Data System (ADS)

    Noda, S.; Yamamoto, S.

    2014-12-01

    In order for Earthquake Early Warning (EEW) to be effective, the rapid determination of magnitude (M) is important. At present, there are no methods which can accurately determine M even for extremely large events (ELE) for EEW, although a number of the methods have been suggested. In order to solve the problem, we use a simple approach derived from the fact that the time difference (Top) from the onset of the body wave to the arrival time of the peak acceleration amplitude of the body wave scales with M. To test this approach, we use 15,172 accelerograms of regional earthquakes (most of them are M4-7 events) from the K-NET, as the first step. Top is defined by analyzing the S-wave in this step. The S-onsets are calculated by adding the theoretical S-P times to the P-onsets which are manually picked. As the result, it is confirmed that logTop has high correlation with Mw, especially for the higher frequency band (> 2Hz). The RMS of residuals between Mw and M estimated in this step is less than 0.5. In case of the 2011 Tohoku earthquake, M is estimated to be 9.01 at 150 seconds after the initiation of the event.To increase the number of the ELE data, we add the teleseismic high frequency P-wave records to the analysis, as the second step. According to the result of various back-projection analyses, we consider the teleseismic P-waves to contain information on the entire rupture process. The BHZ channel data of the Global Seismographic Network for 24 events are used in this step. 2-4Hz data from the stations in the epicentral distance range of 30-85 degrees are used following the method of Hara [2007]. All P-onsets are manually picked. Top obtained from the teleseimic data show good correlation with Mw, complementing the one obtained from the regional data. We conclude that the proposed approach is quite useful for estimating reliable M for EEW, even for the ELE.

  13. Singular F(R) cosmology unifying early- and late-time acceleration with matter and radiation domination era

    NASA Astrophysics Data System (ADS)

    Odintsov, S. D.; Oikonomou, V. K.

    2016-06-01

    We present some cosmological models which unify the late- and early-time acceleration eras with the radiation and the matter domination era, and we realize the cosmological models by using the theoretical framework of F(R) gravity. Particularly, the first model unifies the late- and early-time acceleration with the matter domination era, and the second model unifies all the evolution eras of our Universe. The two models are described in the same way at early and late times, and only the intermediate stages of the evolution have some differences. Each cosmological model contains two Type IV singularities which are chosen to occur one at the end of the inflationary era and one at the end of the matter domination era. The cosmological models at early times are approximately identical to the R 2 inflation model, so these describe a slow-roll inflationary era which ends when the slow-roll parameters become of order one. The inflationary era is followed by the radiation era and after that the matter domination era follows, which lasts until the second Type IV singularity, and then the late-time acceleration era follows. The models have two appealing features: firstly they produce a nearly scale invariant power spectrum of primordial curvature perturbations and a scalar-to-tensor ratio which are compatible with the most recent observational data and secondly, it seems that the deceleration–acceleration transition is crucially affected by the presence of the second Type IV singularity which occurs at the end of the matter domination era. As we demonstrate, the Hubble horizon at early times shrinks, as expected for an initially accelerating Universe, then during the matter domination era, it expands and finally after the Type IV singularity, the Hubble horizon starts to shrink again, during the late-time acceleration era. Intriguingly enough, the deceleration–acceleration transition, occurs after the second Type IV singularity. In addition, we investigate which F

  14. Singular F(R) cosmology unifying early- and late-time acceleration with matter and radiation domination era

    NASA Astrophysics Data System (ADS)

    Odintsov, S. D.; Oikonomou, V. K.

    2016-06-01

    We present some cosmological models which unify the late- and early-time acceleration eras with the radiation and the matter domination era, and we realize the cosmological models by using the theoretical framework of F(R) gravity. Particularly, the first model unifies the late- and early-time acceleration with the matter domination era, and the second model unifies all the evolution eras of our Universe. The two models are described in the same way at early and late times, and only the intermediate stages of the evolution have some differences. Each cosmological model contains two Type IV singularities which are chosen to occur one at the end of the inflationary era and one at the end of the matter domination era. The cosmological models at early times are approximately identical to the R 2 inflation model, so these describe a slow-roll inflationary era which ends when the slow-roll parameters become of order one. The inflationary era is followed by the radiation era and after that the matter domination era follows, which lasts until the second Type IV singularity, and then the late-time acceleration era follows. The models have two appealing features: firstly they produce a nearly scale invariant power spectrum of primordial curvature perturbations and a scalar-to-tensor ratio which are compatible with the most recent observational data and secondly, it seems that the deceleration-acceleration transition is crucially affected by the presence of the second Type IV singularity which occurs at the end of the matter domination era. As we demonstrate, the Hubble horizon at early times shrinks, as expected for an initially accelerating Universe, then during the matter domination era, it expands and finally after the Type IV singularity, the Hubble horizon starts to shrink again, during the late-time acceleration era. Intriguingly enough, the deceleration-acceleration transition, occurs after the second Type IV singularity. In addition, we investigate which F(R) gravity

  15. Thermal history and timing of hydrocarbon expulsion in the Maracaibo basin, Venezuela

    SciTech Connect

    White, C.; Mompart, L.

    1996-08-01

    The aim of this paper is to contribute towards the understanding of the thermal history of La Luna and Orocui source rocks and their related hydrocarbon generation and expulsion in the Maracaibo basin. The paper is derived from an integrated geochemical model obtained during a recent multidisciplinary regional study. Among data compiled or interpreted are geothermal gradients which increase in value towards the northeast and southwest, with a minimum in the west coast of the lake and local maxima along NNE-SSW structural alignments; heat flow value which reflect this same pattern; eroded Eocene sediment thicknesses of up to 1500 ft in the lake area which contrast with 10,000 ft used in previous studies. These data, together with vitrinite reflectance and T{sub max} maturity values, well and seismic isopachs of Cretaceous and Tertiary stratigraphic sequences, were modelled using BasinMod TM, a basin modelling software. Highlights of this are time of expulsion maps that illustrate how the first expulsion of hydrocarbons from La Luna occurred in the northeastern area of the Basin during Early (not Middle) Eocene times. The oil expulsion window migrated towards the southwest and eventually the northwest, but bypassing the western coast of the lake, presently immature (contrary to previous work), and gas expulsion is occurring now in the Miocene trough northwest of the Andes Mountains. The thermal history of the Paleogene source rocks (Orocui Group and Misoa Formation), shows generation/expulsion mainly in the southwest of the Basin, since Late Miocene.

  16. Analysis on the Time and Frequency Domains of the Acceleration in Front Crawl Stroke

    PubMed Central

    Gil, Joaquín Madera; Moreno, Luis-Millán González; Mahiques, Juan Benavent; Muñoz, Víctor Tella

    2012-01-01

    The swimming involves accelerations and decelerations in the swimmer’s body. Thus, the main objective of this study is to make a temporal and frequency analysis of the acceleration in front crawl swimming, regarding the gender and the performance. The sample was composed by 31 male swimmers (15 of high-level and 16 of low-level) and 20 female swimmers (11 of high-level and 9 of low-level). The acceleration was registered from the third complete cycle during eight seconds in a 25 meters maximum velocity test. A position transducer (200Hz) was used to collect the data, and it was synchronized to an aquatic camera (25Hz). The acceleration in the temporal (root mean square, minimum and maximum of the acceleration) and frequency (power peak, power peak frequency and spectral area) domains was calculated with Fourier analysis, as well as the velocity and the spectrums distribution in function to present one or more main peaks (type 1 and type 2). A one-way ANOVA was used to establish differences between gender and performance. Results show differences between genders in all the temporal domain variables (p<0.05) and only the Spectral Area (SA) in the frequency domain (p<0.05). Between gender and performance, only the Root Mean Square (RMS) showed differences in the performance of the male swimmers (p<0.05) and in the higher level swimmers, the Maximum (Max) and the Power Peak (PP) of the acceleration showed differences between both genders (p<0.05). These results confirms the importance of knowing the RMS to determine the efficiency of the swimmers regarding gender and performance level PMID:23487001

  17. Approach for Selection of Rayleigh Damping Parameters Used for Time History Analysis

    SciTech Connect

    R. E. Spears; S. R. Jensen

    2009-07-01

    Nonlinearities, whether geometric or material, need to be addressed in seismic analysis. One good analysis method that can address these nonlinearities is direct time integration with Rayleigh damping. Modal damping is the damping typically specified in seismic analysis Codes and Standards. Modal damping is constant for all frequencies where Rayleigh damping varies with frequency. An approach is proposed here for selection of Rayleigh damping coefficients to be used in seismic analyses that are consistent with given Modal damping. The approach uses the difference between the modal damping response and the Rayleigh damping response along with effective mass properties of the model being evaluated to match overall system response levels. This paper provides a simple example problem to demonstrate the approach. It also provides results for a finite element model representing an existing piping system. Displacement, acceleration, and stress results are compared from model runs using modal damping and model runs using Rayleigh damping with coefficients selected using the proposed method.

  18. Time History of Repeating Low-Frequency Earthquakes Spanning 5 Years

    NASA Astrophysics Data System (ADS)

    Sweet, J. R.; Creager, K. C.

    2011-12-01

    Low-frequency earthquakes (LFEs) are a recently identified class of earthquakes that occur coincidentally with tectonic tremor in time and space. LFEs comprise much of the tectonic tremor in Japan, and LFE locations have been used to pin down the location of tremor bursts within subduction zones around the world (Brown et al., 2009, GRL), as well as on deep segments of the San Andreas Fault (Shelly et al., 2009, GRL). While prior LFE studies have allowed us to see where and when various fault patches are radiating seismic energy with unprecedented detail, the time history of repeating LFEs has received less attention. Using well-recorded LFEs as templates, we employ a cross-correlation filter to find matching events. We have identified several locations in the northern Cascadia subduction zone which produce LFEs that repeated several hundred times during the past five years. The LFEs are active during multiple Episodic Tremor and Slip (ETS) events. In each case, the matching events first appear rather suddenly and at a feverish pace. Following this initial burst of several hours, the events exhibit a much more discrete pattern of recurrence that starts out as frequent pops that become less and less frequent over a period of several days. We suggest that the initial burst is associated with the passage of a slip front on the fault surface at the location of the template event. Later pops may be attributed to resurgent slow slip that briefly generates seismic energy during the days following the passage of the initial slip front. One LFE template was also active during an inter-ETS event. Its time history was similar to the initial bursts during the ETS events, but it was not followed by the later pops-perhaps due to the absence of resurgent slow slip during the small inter-ETS event. We have previously identified several additional LFE templates that occurred during smaller inter-ETS episodes farther downdip of the main ETS zone. Using these additional templates, we

  19. Harnessing data structure for recovery of randomly missing structural vibration responses time history: Sparse representation versus low-rank structure

    NASA Astrophysics Data System (ADS)

    Yang, Yongchao; Nagarajaiah, Satish

    2016-06-01

    Randomly missing data of structural vibration responses time history often occurs in structural dynamics and health monitoring. For example, structural vibration responses are often corrupted by outliers or erroneous measurements due to sensor malfunction; in wireless sensing platforms, data loss during wireless communication is a common issue. Besides, to alleviate the wireless data sampling or communication burden, certain accounts of data are often discarded during sampling or before transmission. In these and other applications, recovery of the randomly missing structural vibration responses from the available, incomplete data, is essential for system identification and structural health monitoring; it is an ill-posed inverse problem, however. This paper explicitly harnesses the data structure itself-of the structural vibration responses-to address this (inverse) problem. What is relevant is an empirical, but often practically true, observation, that is, typically there are only few modes active in the structural vibration responses; hence a sparse representation (in frequency domain) of the single-channel data vector, or, a low-rank structure (by singular value decomposition) of the multi-channel data matrix. Exploiting such prior knowledge of data structure (intra-channel sparse or inter-channel low-rank), the new theories of ℓ1-minimization sparse recovery and nuclear-norm-minimization low-rank matrix completion enable recovery of the randomly missing or corrupted structural vibration response data. The performance of these two alternatives, in terms of recovery accuracy and computational time under different data missing rates, is investigated on a few structural vibration response data sets-the seismic responses of the super high-rise Canton Tower and the structural health monitoring accelerations of a real large-scale cable-stayed bridge. Encouraging results are obtained and the applicability and limitation of the presented methods are discussed.

  20. An Experiment in ''Less Time, More Options": A Study of Accelerated University Students.

    ERIC Educational Resources Information Center

    Litwin, James L.; And Others

    This study investigated the characteristics and experiences of 59 college students accelerated from their freshman to their junior year. The students showed high academic performance and few social problems, but questions of personal identity remained problematic; the best single predictor of academic success was found to be freshman grade-point…

  1. Deformed phase space Kaluza-Klein cosmology and late time acceleration

    NASA Astrophysics Data System (ADS)

    Sabido, M.; Yee-Romero, C.

    2016-06-01

    The effects of phase space deformations on Kaluza-Klein cosmology are studied. The deformation is introduced by modifying the symplectic structure of the minisuperspace variables. In the deformed model, we find an accelerating scale factor and therefore infer the existence of an effective cosmological constant from the phase space deformation parameter β.

  2. Environmental Contingency in Life History Strategies: The Influence of Mortality and Socioeconomic Status on Reproductive Timing

    PubMed Central

    Griskevicius, Vladas; Delton, Andrew W.; Robertson, Theresa E.; Tybur, Joshua M.

    2013-01-01

    Why do some people have children early, whereas others delay reproduction? By considering the trade-offs between using one’s resources for reproduction versus other tasks, the evolutionary framework of life history theory predicts that reproductive timing should be influenced by mortality and resource scarcity. A series of experiments examined how mortality cues influenced the desire to have children sooner rather than later. The effects of mortality depended critically on whether people grew up in a relatively resource-scarce or resource-plentiful environment. For individuals growing up relatively poor, mortality cues produced a desire to reproduce sooner—to want children now, even at the cost of furthering one’s education or career. Conversely, for individuals growing up relatively wealthy, mortality cues produced a desire to delay reproduction—to further one’s education or career before starting a family. Overall, mortality cues appear to shift individuals into different life history strategies as a function of childhood socioeconomic status, suggesting important implications for how environmental factors can influence fertility and family size. PMID:20873933

  3. A computer program for estimating the power-density spectrum of advanced continuous simulation language generated time histories

    NASA Technical Reports Server (NTRS)

    Dunn, H. J.

    1981-01-01

    A computer program for performing frequency analysis of time history data is presented. The program uses circular convolution and the fast Fourier transform to calculate power density spectrum (PDS) of time history data. The program interfaces with the advanced continuous simulation language (ACSL) so that a frequency analysis may be performed on ACSL generated simulation variables. An example of the calculation of the PDS of a Van de Pol oscillator is presented.

  4. History of teaching anatomy in India: from ancient to modern times.

    PubMed

    Jacob, Tony George

    2013-01-01

    Safe clinical practice is based on a sound knowledge of the structure and function of the human body. Thus, knowledge of anatomy has been an essential tool in the practice of healthcare throughout the ages. The history of anatomy in India traces from the Paleolithic Age to the Indus Valley Civilization, the Vedic Times, the Islamic Dynasties, the modern Colonial Period, and finally to Independent India. The course of the study of anatomy, despite accompanying controversies and periods of latencies, has been fascinating. This review takes the reader through various periods of Indian medicine and the role of anatomy in the field of medical practice. It also provides a peek into the modern system of pedagogy in anatomical sciences in India.

  5. Estimating time to contact and impact velocity when catching an accelerating object with the hand.

    PubMed

    Senot, Patrice; Prévost, Pascal; McIntyre, Joseph

    2003-02-01

    To catch a moving object with the hand requires precise coordination between visual information about the target's motion and the muscle activity necessary to prepare for the impact. A key question remains open as to if and how a human observer uses velocity and acceleration information when controlling muscles in anticipation of impact. Participants were asked to catch the moving end of a swinging counterweighted pendulum, and resulting muscle activities in the arm were measured. The authors also simulated muscle activities that would be produced according to different tuning strategies. By comparing data with simulations, the authors provide evidence that human observers use online information about velocity but not acceleration when preparing for impact.

  6. Instability of multi-layer fluid configurations in the presence of time-dependent accelerations in a microgravity environment

    NASA Technical Reports Server (NTRS)

    Lyell, M. J.; Roh, Michael

    1991-01-01

    The increasing number of research opportunities in a microgravity environment will benefit not only fundamental studies in fluid dynamics, but also technological applications such as those involving materials processing. In particular, fluid configurations which involve fluid-fluid interfaces would occur in a variety of experimental investigations. This work investigates the stability of a configuration involving fluid-fluid interfaces in the presence of a time-dependent forcing. Both periodic (g-jitter) and nonperiodic accelerations are considered. The fluid configuration is multilayered, and infinite in extent. The analysis is linear and inviscid, and the acceleration vector is oriented perpendicular to each interface. A Floquet analysis is employed in the case of the periodic forcing. In the problem of nonperiodic forcing, the resulting system of equations are integrated in time. Specific nondimensional parameters appear in each problem. The configuration behavior is investigated for a range of parameter values.

  7. Fast history matching of time-lapse seismic and production data for high resolution models

    NASA Astrophysics Data System (ADS)

    Jimenez Arismendi, Eduardo Antonio

    Integrated reservoir modeling has become an important part of day-to-day decision analysis in oil and gas management practices. A very attractive and promising technology is the use of time-lapse or 4D seismic as an essential component in subsurface modeling. Today, 4D seismic is enabling oil companies to optimize production and increase recovery through monitoring fluid movements throughout the reservoir. 4D seismic advances are also being driven by an increased need by the petroleum engineering community to become more quantitative and accurate in our ability to monitor reservoir processes. Qualitative interpretations of time-lapse anomalies are being replaced by quantitative inversions of 4D seismic data to produce accurate maps of fluid saturations, pore pressure, temperature, among others. Within all steps involved in this subsurface modeling process, the most demanding one is integrating the geologic model with dynamic field data, including 4Dseismic when available. The validation of the geologic model with observed dynamic data is accomplished through a "history matching" (HM) process typically carried out with well-based measurements. Due to low resolution of production data, the validation process is severely limited in its reservoir areal coverage, compromising the quality of the model and any subsequent predictive exercise. This research will aim to provide a novel history matching approach that can use information from high-resolution seismic data to supplement the areally sparse production data. The proposed approach will utilize streamline-derived sensitivities as means of relating the forward model performance with the prior geologic model. The essential ideas underlying this approach are similar to those used for high-frequency approximations in seismic wave propagation. In both cases, this leads to solutions that are defined along "streamlines" (fluid flow), or "rays" (seismic wave propagation). Synthetic and field data examples will be used

  8. Continued Investigations of the Accretion History of Extraterrestrial Matter over Geologic Time

    NASA Technical Reports Server (NTRS)

    Farley, Kenneth

    2001-01-01

    This grant supported our ongoing project to characterize the accretion rate of interplanetary dust particles (IDPs) to Earth over geologic time using He-3 as a tracer. IDPs are derived from collisions in the asteroid belt and from disaggregation of active comets. Owing to their small size (few to few hundred micrometers diameter) these particles spiral into the sun under Poynting-Robertson drag typically in less than a few tens of kyrs. Thus IDPs must be continually resupplied to the zodiacal cloud, and because the processes of IDP production are likely to be sporadic, time variation in the IDP accretion rate to Earth is likely to be time-varying. For example, major asteroidal collisions and comet showers should greatly enhance the IDP accretion rate. Our ultimate objective (still ongoing) is to document this time variance so as to better understand the history of the solar system, the source of IDPs accreting to Earth, and the details of the mechanism by which particles are captured by Earth. To document variations in IDP accretion rate through time we use He-3 as a tracer. This isotope is in extremely low abundance in terrestrial matter, but IDPs have very high concentrations of He-3 from implantation of solar wind ions. By measuring He-3 in seafloor sediments, we can estimate the IDP accretion rate for at least the last few hundred Myrs. Under an earlier NASA grant we identified the existence of a large increase in He-3 flux in the Late Eocene (35 Myr ago), coincident with the two largest impact craters of the Cenozoic Era. The simplest interpretation of this observation is the occurrence of a shower of long period comets at that time, simultaneously increasing the impact cratering probability and accretion rate of IDPs to Earth (Farley et al., 1998). Comet showers produced by stellar perturbation of the Oort cloud should be fairly common in the geologic record, so this is not an unreasonable interpretation of our observations.

  9. Time-dependent regulation of yeast glycolysis upon nitrogen starvation depends on cell history.

    PubMed

    van Eunen, K; Dool, P; Canelas, A B; Kiewiet, J; Bouwman, J; van Gulik, W M; Westerhoff, H V; Bakker, B M

    2010-03-01

    In this study, the authors investigated how the glycolytic flux was regulated in time upon nitrogen starvation of cells with different growth histories. We have compared cells grown in glucose-limited chemostat cultures under respiratory conditions (low dilution rate of 0.1/h) to cells grown under respirofermentative conditions (high dilution rate of 0.35/h). The fermentative capacity was lower in cells grown under respiratory conditions than in cells grown under respirofermentative conditions, yet more resilient to prolonged nitrogen starvation. The time profiles revealed that the fermentative capacity even increased in cells grown under respiratory conditions during the first hours of nitrogen starvation. In cells grown under respirofermentative conditions the fermentative capacity decreased from the onset of nitrogen starvation. We have applied time-dependent Regulation Analysis to follow the fermentative capacity during nitrogen starvation. In both experiments, diverse categories of regulation were found. However, in the cells grown under respiratory conditions regulation was predominantly metabolic, whereas in the cells grown under respirofermentative conditions hierarchical regulation was dominant. To study the metabolic regulation, concentrations of intracellular metabolites, including allosteric regulators, were measured. The obtained results can explain some aspects of the metabolic regulation, but not all.

  10. Real-Time CME Forecasting Using HMI Active-Region Magnetograms and Flare History

    NASA Technical Reports Server (NTRS)

    Falconer, David; Moore, Ron; Barghouty, Abdulnasser F.; Khazanov, Igor

    2011-01-01

    We have recently developed a method of predicting an active region s probability of producing a CME, an X-class Flare, an M-class Flare, or a Solar Energetic Particle Event from a free-energy proxy measured from SOHO/MDI line-of-sight magnetograms. This year we have added three major improvements to our forecast tool: 1) Transition from MDI magnetogram to SDO/HMI magnetogram allowing us near-real-time forecasts, 2) Automation of acquisition and measurement of HMI magnetograms giving us near-real-time forecasts (no older than 2 hours), and 3) Determination of how to improve forecast by using the active region s previous flare history in combination with its free-energy proxy. HMI was turned on in May 2010 and MDI was turned off in April 2011. Using the overlap period, we have calibrated HMI to yield what MDI would measure. This is important since the value of the free-energy proxy used for our forecast is resolution dependent, and the forecasts are made from results of a 1996-2004 database of MDI observations. With near-real-time magnetograms from HMI, near-real-time forecasts are now possible. We have augmented the code so that it continually acquires and measures new magnetograms as they become available online, and updates the whole-sun forecast from the coming day. The next planned improvement is to use an active region s previous flare history, in conjunction with its free-energy proxy, to forecast the active region s event rate. It has long been known that active regions that have produced flares in the past are likely to produce flares in the future, and that active regions that are nonpotential (have large free-energy) are more likely to produce flares in the future. This year we have determined that persistence of flaring is not just a reflection of an active region s free energy. In other words, after controlling for free energy, we have found that active regions that have flared recently are more likely to flare in the future.

  11. Modelling the thermal history of Vesta: time scale of accretion and differentiation.

    NASA Astrophysics Data System (ADS)

    Formisano, M.; Federico, C.; Turrini, D.; Capaccioni, F.

    2012-04-01

    Vesta is the only known intact primordial asteroid in the Solar System showing an internal differentiated structure, as inferred by its spectral connection with HED meteorites (Keil et al. 2002, Scott 2007, Coradini et al. 2011). Recent results (Schiller et al. 2011) indicate a faster cooling of the interior of Vesta than previously thought. If confirmed, this would imply that the thermal history of Vesta diverges from the generally accepted picture (Ghosh & Mc Sween 1998). Using the thermal evolution code (Formisano et al. 2011) we developed, we are simulating several thermal and structural evolution scenarios of Vesta, by varying the delay Δtd in the injection of 26Al in Vesta, which controls the strength of radiogenic sources. We consider a primordial Vesta as a sphere of radius 270 Km with the initial temperature fixed to 200 K. The initial composition is a homogeneous mixture of silicatic (77%) and metallic (23%) material. Our code solves contemporary the heat equation with the source term (i.e. the energy is supplied by the decay of 26Al, 60Fe ) and the equation for the mass transfer in a porous medium, by using a finite difference 1D method. When the melting temperature of Fe-FeS is reached, the percolation of the iron into the silicatic matrix takes place while, when the melting temperature of silicate is reached, the differentiation and subsequent core formation occur. Since our model does not take in account heat removal mechanisms other than the conduction and the irradiation at the surface, our results supply a reliable picture of the thermal history of Vesta up until the onset of the differentiation. When compared to the data provided by HED meteorites, our results suggest short accretion and differentiation times of Vesta respect to the condensation of CAIs. The scenarios characterized by Δtd > 2 Ma show temperatures not reaching the melting temperature of silicate and for this reason they are incompatible with the basaltic magmatism suggest by HEDs

  12. New Features of Time Domain Electric-Field Structures in the Auroral Acceleration Region

    SciTech Connect

    Mozer, F.S.; Ergun, R.; Temerin, M.; Cattell, C.; Dombeck, J.; Wygant, J.

    1997-08-01

    The Polar Satellite carries the first three-axis electric field detector flown in the magnetosphere. Its direct measurement of electric field components perpendicular and parallel to the local magnetic field has revealed new classes and features of electric field structures associated with the plasma acceleration that produces discrete auroras and that populates the magnetosphere with plasma of ionospheric origin. These structures, associated with the hydrogen ion cyclotron mode, include very large solitary waves, spiky field structures, wave envelopes of parallel electric fields, and very large amplitude, nonlinear, coherent ion cyclotron waves. {copyright} {ital 1997} {ital The American Physical Society}

  13. Prediction of broadband ground-motion time histories: Hybrid low/high-frequency method with correlated random source parameters

    USGS Publications Warehouse

    Liu, P.; Archuleta, R.J.; Hartzell, S.H.

    2006-01-01

    We present a new method for calculating broadband time histories of ground motion based on a hybrid low-frequency/high-frequency approach with correlated source parameters. Using a finite-difference method we calculate low- frequency synthetics (< ∼1 Hz) in a 3D velocity structure. We also compute broadband synthetics in a 1D velocity model using a frequency-wavenumber method. The low frequencies from the 3D calculation are combined with the high frequencies from the 1D calculation by using matched filtering at a crossover frequency of 1 Hz. The source description, common to both the 1D and 3D synthetics, is based on correlated random distributions for the slip amplitude, rupture velocity, and rise time on the fault. This source description allows for the specification of source parameters independent of any a priori inversion results. In our broadband modeling we include correlation between slip amplitude, rupture velocity, and rise time, as suggested by dynamic fault modeling. The method of using correlated random source parameters is flexible and can be easily modified to adjust to our changing understanding of earthquake ruptures. A realistic attenuation model is common to both the 3D and 1D calculations that form the low- and high-frequency components of the broadband synthetics. The value of Q is a function of the local shear-wave velocity. To produce more accurate high-frequency amplitudes and durations, the 1D synthetics are corrected with a randomized, frequency-dependent radiation pattern. The 1D synthetics are further corrected for local site and nonlinear soil effects by using a 1D nonlinear propagation code and generic velocity structure appropriate for the site’s National Earthquake Hazards Reduction Program (NEHRP) site classification. The entire procedure is validated by comparison with the 1994 Northridge, California, strong ground motion data set. The bias and error found here for response spectral acceleration are similar to the best results

  14. Applying shape selection methods to Landsat time series for mapping forest disturbance history and cause

    NASA Astrophysics Data System (ADS)

    Schleeweis, K.; Moisen, G.; Meyer, M. C.; Schroeder, T. A.; Toney, C.; Liao, X.; Cohen, W. B.; Healey, S. P.

    2014-12-01

    In the US, nationwide processing of historic Landsat data has recently been completed to provide a comprehensive annual, wall-to-wall analysis of US disturbance history and cause 1982-2011. Here, we present new methodology used in this effort that involves fitting nonparametric shape-restricted regression splines to Landsat spectral trajectories which are sensitive to both forest structure (eg., Band 5) and leaf area (eg., NDVI ). The functions, developed in R and automated for nationwide processing, deliver a series of parameters for each pixel and band that identify the best (of seven possible) shapes of the spectral pattern, year(s) of inflection, magnitude, and pre- and post- inflection rates of growth or recovery. Parameters from model fits are then fed into random forests models along with static bioclimatic and vegetation data layers to predict causal agent through time. Results indicate shape parameters are the driving predictors in diverse Landsat scenes across the US, and are able to capture subtle patterns produced by low magnitude or slow change such as insect and disease. We discuss the interaction between shape parameters in the empirical models, and illustrate how the intermediate product of the fitted trajectories themselves can be used as ancillary data in model-assisted estimates of forest attributes through time.

  15. Time history prediction of direct-drive implosions on the Omega facility

    DOE PAGES

    Laffite, S.; Bourgade, J. L.; Caillaud, T.; Delettrez, J A; Frenje, J. A.; Girard, F.; Glebov, V. Yu.; Joshi, Tirtha Raj; Landoas, O.; Legay, G.; et al

    2016-01-14

    We present in this article direct-drive experiments that were carried out on the Omega facility [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)]. Two different pulse shapes were tested in order to vary the implosion stability of the same target whose parameters, dimensions and composition, remained the same. The direct-drive configuration on the Omega facility allows the accurate time-resolvedmeasurement of the scattered light. We show that, provided the laser coupling is well controlled, the implosion time history, assessed by the “bang-time” and the shell trajectory measurements, can be predicted. This conclusion is independent on the pulse shape. Inmore » contrast, we show that the pulse shape affects the implosion stability, assessed by comparing the target performances between prediction and measurement. For the 1-ns square pulse, the measuredneutron number is about 80% of the prediction. Lastly, for the 2-step 2-ns pulse, we test here that this ratio falls to about 20%.« less

  16. Reconstructing disturbance history for an intensively mined region by time-series analysis of Landsat imagery.

    PubMed

    Li, Jing; Zipper, Carl E; Donovan, Patricia F; Wynne, Randolph H; Oliphant, Adam J

    2015-09-01

    Surface mining disturbances have attracted attention globally due to extensive influence on topography, land use, ecosystems, and human populations in mineral-rich regions. We analyzed a time series of Landsat satellite imagery to produce a 28-year disturbance history for surface coal mining in a segment of eastern USA's central Appalachian coalfield, southwestern Virginia. The method was developed and applied as a three-step sequence: vegetation index selection, persistent vegetation identification, and mined-land delineation by year of disturbance. The overall classification accuracy and kappa coefficient were 0.9350 and 0.9252, respectively. Most surface coal mines were identified correctly by location and by time of initial disturbance. More than 8 % of southwestern Virginia's >4000-km(2) coalfield area was disturbed by surface coal mining over the 28-year period. Approximately 19.5 % of the Appalachian coalfield surface within the most intensively mined county (Wise County) has been disturbed by mining. Mining disturbances expanded steadily and progressively over the study period. Information generated can be applied to gain further insight concerning mining influences on ecosystems and other essential environmental features.

  17. Time histories of horizontal-tail loads, elevator loads, and deformations on a jet-powered bomber airplane during abrupt pitching maneuvers at approximately 20,000 feet

    NASA Technical Reports Server (NTRS)

    Wiener, Bernard; Harris, Agnes E

    1950-01-01

    Time histories are presented of horizontal-tail loads, elevator loads, and deformations on a jet-powered bomber during abrupt pitching maneuvers at a pressure altitude of approximately 20,000 feet. The normal and pitching accelerations measured varied from -0.90b to 3.41g and from -0.73 to 0.80 radian per second per second (sic), respectively, with a Mach number variation of from 0.40 to o.75. The maximum horizontal-tail load measured was 17,250 pounds down. The maximum elevator load was 1900 pounds up. The stabilizer twisted a maximum of 0.76 degrees leading edge down at the tip. The greatest fuselage deflection at the tail was about 1.7 inches down.

  18. Real-time dedispersion for fast radio transient surveys, using auto tuning on many-core accelerators

    NASA Astrophysics Data System (ADS)

    Sclocco, A.; van Leeuwen, J.; Bal, H. E.; van Nieuwpoort, R. V.

    2016-01-01

    Dedispersion, the removal of deleterious smearing of impulsive signals by the interstellar matter, is one of the most intensive processing steps in any radio survey for pulsars and fast transients. We here present a study of the parallelization of this algorithm on many-core accelerators, including GPUs from AMD and NVIDIA, and the Intel Xeon Phi. We find that dedispersion is inherently memory-bound. Even in a perfect scenario, hardware limitations keep the arithmetic intensity low, thus limiting performance. We next exploit auto-tuning to adapt dedispersion to different accelerators, observations, and even telescopes. We demonstrate that the optimal settings differ between observational setups, and that auto-tuning significantly improves performance. This impacts time-domain surveys from Apertif to SKA.

  19. On the acceleration of ions by interplanetary shock waves. 3: High time resolution observations of CIR proton events

    NASA Technical Reports Server (NTRS)

    Pesses, M. E.; Vanallen, J. A.; Tsurutani, B. T.; Smith, E. J.

    1981-01-01

    Observations within + or - 3 hours of corotating interaction region (CIR) shock waves of proton intensities, pitch angle distribution and crude differential energy spectra of the range of 0.6 E sub p 3.4 MeV are presented. The principle result is the evidence for the persistent flow of particles away from the shock. The observations are found to be in good agreement with the hypothesis of local interplanetary shock acceleration by the shock drift and compression mechanisms. The same set of observations strongly suggest that transit time damping does not play an important role in the acceleration of protons to 1 MeV in the immediate vicinity of CIR shocks.

  20. Child Mortality Estimation: Appropriate Time Periods for Child Mortality Estimates from Full Birth Histories

    PubMed Central

    Pedersen, Jon; Liu, Jing

    2012-01-01

    Background Child mortality estimates from complete birth histories from Demographic and Health Surveys (DHS) surveys and similar surveys are a chief source of data used to track Millennium Development Goal 4, which aims for a reduction of under-five mortality by two-thirds between 1990 and 2015. Based on the expected sample sizes when the DHS program commenced, the estimates are usually based on 5-y time periods. Recent surveys have had larger sample sizes than early surveys, and here we aimed to explore the benefits of using shorter time periods than 5 y for estimation. We also explore the benefit of changing the estimation procedure from being based on years before the survey, i.e., measured with reference to the date of the interview for each woman, to being based on calendar years. Methods and Findings Jackknife variance estimation was used to calculate standard errors for 207 DHS surveys in order to explore to what extent the large samples in recent surveys can be used to produce estimates based on 1-, 2-, 3-, 4-, and 5-y periods. We also recalculated the estimates for the surveys into calendar-year-based estimates. We demonstrate that estimation for 1-y periods is indeed possible for many recent surveys. Conclusions The reduction in bias achieved using 1-y periods and calendar-year-based estimation is worthwhile in some cases. In particular, it allows tracking of the effects of particular events such as droughts, epidemics, or conflict on child mortality in a way not possible with previous estimation procedures. Recommendations to use estimation for short time periods when possible and to use calendar-year-based estimation were adopted in the United Nations 2011 estimates of child mortality. PMID:22952435

  1. Earth History databases and visualization - the TimeScale Creator system

    NASA Astrophysics Data System (ADS)

    Ogg, James; Lugowski, Adam; Gradstein, Felix

    2010-05-01

    The "TimeScale Creator" team (www.tscreator.org) and the Subcommission on Stratigraphic Information (stratigraphy.science.purdue.edu) of the International Commission on Stratigraphy (www.stratigraphy.org) has worked with numerous geoscientists and geological surveys to prepare reference datasets for global and regional stratigraphy. All events are currently calibrated to Geologic Time Scale 2004 (Gradstein et al., 2004, Cambridge Univ. Press) and Concise Geologic Time Scale (Ogg et al., 2008, Cambridge Univ. Press); but the array of intercalibrations enable dynamic adjustment to future numerical age scales and interpolation methods. The main "global" database contains over 25,000 events/zones from paleontology, geomagnetics, sea-level and sequence stratigraphy, igneous provinces, bolide impacts, plus several stable isotope curves and image sets. Several regional datasets are provided in conjunction with geological surveys, with numerical ages interpolated using a similar flexible inter-calibration procedure. For example, a joint program with Geoscience Australia has compiled an extensive Australian regional biostratigraphy and a full array of basin lithologic columns with each formation linked to public lexicons of all Proterozoic through Phanerozoic basins - nearly 500 columns of over 9,000 data lines plus hot-curser links to oil-gas reference wells. Other datapacks include New Zealand biostratigraphy and basin transects (ca. 200 columns), Russian biostratigraphy, British Isles regional stratigraphy, Gulf of Mexico biostratigraphy and lithostratigraphy, high-resolution Neogene stable isotope curves and ice-core data, human cultural episodes, and Circum-Arctic stratigraphy sets. The growing library of datasets is designed for viewing and chart-making in the free "TimeScale Creator" JAVA package. This visualization system produces a screen display of the user-selected time-span and the selected columns of geologic time scale information. The user can change the

  2. The timing of life history events in the presence of soft disturbances.

    PubMed

    Bertacchi, Daniela; Zucca, Fabio; Ambrosini, Roberto

    2016-01-21

    We study a model for the evolutionarily stable strategy (ESS) used by biological populations for choosing the time of life-history events, such as arrival from migration and breeding. In our model we account for both intra-species competition (early individuals have a competitive advantage) and a disturbance which strikes at a random time, killing a fraction 1-p of the population. Disturbances include spells of bad weather, such as freezing or heavily raining days. It has been shown by Iwasa and Levin (1995) that when the disturbance is so strong that it kills any individual present when it strikes (hard disturbance, p=0), then the ESS is a mixed strategy (individuals choose their arrival date in an interval of possible dates, according to a certain probability distribution). In this case, individuals wait for a certain time and afterwards start arriving (or breeding) every day. In this paper we explore a biologically more realistic situation whereby the disturbance kills only a fraction of the individuals (soft disturbance, p>0). We also remove some technical assumptions which Iwasa and Levin made on the distribution of the disturbance. We prove that the ESS is still a mixed choice of times, however with respect to the case of hard disturbance, a new phenomenon arises: whenever the disturbance is soft, if the competition is sufficiently strong, the waiting time disappears and a fraction of the population arrives at the earliest day possible, while the rest will arrive throughout the whole period during which the disturbance may occur. This means that under strong competition, the payoff of early arrival balances the increased risk of being killed by the disturbance. We study the behaviour of the ESS and of the average fitness of the population, depending on the parameters involved. We also investigate how the population may be affected by climate change: namely the occurrence of more extreme weather events, which may kill a larger fraction of the population, and

  3. Two-dimensional time-dependent vortex regions based on the acceleration magnitude.

    PubMed

    Kasten, Jens; Reininghaus, Jan; Hotz, Ingrid; Hege, Hans-Christian

    2011-12-01

    Acceleration is a fundamental quantity of flow fields that captures Galilean invariant properties of particle motion. Considering the magnitude of this field, minima represent characteristic structures of the flow that can be classified as saddle- or vortex-like. We made the interesting observation that vortex-like minima are enclosed by particularly pronounced ridges. This makes it possible to define boundaries of vortex regions in a parameter-free way. Utilizing scalar field topology, a robust algorithm can be designed to extract such boundaries. They can be arbitrarily shaped. An efficient tracking algorithm allows us to display the temporal evolution of vortices. Various vortex models are used to evaluate the method. We apply our method to two-dimensional model systems from computational fluid dynamics and compare the results to those arising from existing definitions.

  4. Generation of Stationary Non-Gaussian Time Histories with a Specified Cross-spectral Density

    DOE PAGES

    Smallwood, David O.

    1997-01-01

    The paper reviews several methods for the generation of stationary realizations of sampled time histories with non-Gaussian distributions and introduces a new method which can be used to control the cross-spectral density matrix and the probability density functions (pdfs) of the multiple input problem. Discussed first are two methods for the specialized case of matching the auto (power) spectrum, the skewness, and kurtosis using generalized shot noise and using polynomial functions. It is then shown that the skewness and kurtosis can also be controlled by the phase of a complex frequency domain description of the random process. The general casemore » of matching a target probability density function using a zero memory nonlinear (ZMNL) function is then covered. Next methods for generating vectors of random variables with a specified covariance matrix for a class of spherically invariant random vectors (SIRV) are discussed. Finally the general case of matching the cross-spectral density matrix of a vector of inputs with non-Gaussian marginal distributions is presented.« less

  5. Aircraft Control Using Engine Thrust: A History of Learning TOC Real-Time

    NASA Technical Reports Server (NTRS)

    Cole, Jennifer H.

    2006-01-01

    A history of learning the operation of Throttles Only Control (TOC) to control an aircraft in real time using engine thrust is shown. The topics include: 1) Past TOC Accidents/Incidents; 2) 1972: DC-10 American Airlines; 3) May 1974: USAF B-52H; 4) April 1975: USAF C-5A; 5) April 1975: USAF C-5A; 6) 1981: USAF B-52G; 7) August 1985: JAL 123 B-747; 8) JAL 123 Survivor Story; 9) JAL 123 Investigation Findings; 10) July 1989: UAL 232 DC-10; 11) UAL 232 DC-10; 12) Eastwind 517 B-737; 13) November 2003: DHL A-300; 14) Historically, TOC has saved lives; 15) Automated Throttles-Only Control; 16) PCA Project; 17) Propulsion-Controlled Aircraft; 18) MD-11 PCA System and Flight Test Envelope; 19) MD-11 Simulation, PCA ILS-Soupled Landing Dispersion; 20) Throttles-Only Pitch and Roll Control Power; 21) PCA in Commercial Fleet; 22) Fall 2005: PCAR Project; 23) PCAR Background - TOC; and 24) PCAR Background - TOC.

  6. Life History and Reproductive Timing of the Endangered Illinois Cave Amphipod, Gammarus acherondytes

    NASA Astrophysics Data System (ADS)

    Venarsky, M. P.; Wilhelm, F. M.; Anderson, F. A.; Taylor, S. J.

    2005-05-01

    To aid the recovery of endangered species requires an understanding of their basic biology. Armed with such knowledge, meaningful management plans with realistic objectives can be established. We examined the life history and reproductive biology of Gammarus acherondytes, a federally endangered cave amphipod, in Reverse Stream, Monroe Co., Illinois. The population was sampled non-destructively at monthly intervals from October 2003 to February 2005. The density of gravid females peaked twice annually, (November-December and June-July) indicating major reproductive events. Gravid females also occurred at other times of the year but at low densities. Two major peaks in the density of newborn young were also observed, which lagged the density of gravid females by approximately 1-2 months. We believe this reproductive pattern is related to the influx of organic matter from mid summer storm events and leaf abscission in autumn. Young grew at a rate of 0.034 mm/day and likely reach reproductive size in one year. Adults are iteroparous and may live for several years. Our results suggest that limiting cave access in highly visited caves during peak reproduction may be a simple strategy to increase the abundance of G. acherondytes.

  7. Nuclear event time histories and computed site transfer functions for locations in the Los Angeles region

    USGS Publications Warehouse

    Rogers, A.M.; Covington, P.A.; Park, R.B.; Borcherdt, R.D.; Perkins, D.M.

    1980-01-01

    This report presents a collection of Nevada Test Site (NTS) nuclear explosion recordings obtained at sites in the greater Los Angeles, Calif., region. The report includes ground velocity time histories, as well as, derived site transfer functions. These data have been collected as part of a study to evaluate the validity of using low-level ground motions to predict the frequency-dependent response of a site during an earthquake. For this study 19 nuclear events were recorded at 98 separate locations. Some of these sites have recorded more than one of the nuclear explosions, and, consequently, there are a total of 159, three-component station records. The location of all the recording sites are shown in figures 1–5, the station coordinates and abbreviations are given in table 1. The station addresses are listed in table 2, and the nuclear explosions that were recorded are listed in table 3. The recording sites were chosen on the basis of three criteria: (1) that the underlying geological conditions were representative of conditions over significant areas of the region, (2) that the site was the location of a strong-motion recording of the 1971 San Fernando earthquake, or (3) that more complete geographical coverage was required in that location.

  8. Orbit Determination and Navigation of the Time History of Events and Macroscale Interactions during Substorms (THEMIS)

    NASA Technical Reports Server (NTRS)

    Morinelli, Patrick; Cosgrove, jennifer; Blizzard, Mike; Nicholson, Ann; Robertson, Mika

    2007-01-01

    This paper provides an overview of the launch and early orbit activities performed by the NASA Goddard Space Flight Center's (GSFC) Flight Dynamics Facility (FDF) in support of five probes comprising the Time History of Events and Macroscale Interactions during Substorms (THEMIS) spacecraft. The FDF was tasked to support THEMIS in a limited capacity providing backup orbit determination support for validation purposes for all five THEMIS probes during launch plus 30 days in coordination with University of California Berkeley Flight Dynamics Center (UCB/FDC). The FDF's orbit determination responsibilities were originally planned to be as a backup to the UCB/FDC for validation purposes only. However, various challenges early on in the mission and a Spacecraft Emergency declared thirty hours after launch placed the FDF team in the role of providing the orbit solutions that enabled contact with each of the probes and the eventual termination of the Spacecraft Emergency. This paper details the challenges and various techniques used by the GSFC FDF team to successfully perform orbit determination for all five THEMIS probes during the early mission. In addition, actual THEMIS orbit determination results are presented spanning the launch and early orbit mission phase. Lastly, this paper enumerates lessons learned from the THEMIS mission, as well as demonstrates the broad range of resources and capabilities within the FDF for supporting critical launch and early orbit navigation activities, especially challenging for constellation missions.

  9. Orbit Determination and Navigation of the Time History of Events and Macroscale Interactions during Substorms (THEMIS)

    NASA Technical Reports Server (NTRS)

    Morinelli, Patrick; Cosgrove, Jennifer; Blizzard, Mike; Robertson, Mike

    2007-01-01

    This paper provides an overview of the launch and early orbit activities performed by the NASA Goddard Space Flight Center's (GSFC) Flight Dynamics Facility (FDF) in support of five probes comprising the Time History of Events and Macroscale Interactions during Substorms (THEMIS) spacecraft. The FDF was tasked to support THEMIS in a limited capacity providing backup orbit determination support for validation purposes for all five THEMIS probes during launch plus 30 days in coordination with University of California Berkeley Flight Dynamics Center (UCB/FDC)2. The FDF's orbit determination responsibilities were originally planned to be as a backup to the UCB/FDC for validation purposes only. However, various challenges early on in the mission and a Spacecraft Emergency declared thirty hours after launch placed the FDF team in the role of providing the orbit solutions that enabled contact with each of the probes and the eventual termination of the Spacecraft Emergency. This paper details the challenges and various techniques used by the GSFC FDF team to successfully perform orbit determination for all five THEMIS probes during the early mission. In addition, actual THEMIS orbit determination results are presented spanning the launch and early orbit mission phase. Lastly, this paper enumerates lessons learned from the THEMIS mission, as well as demonstrates the broad range of resources and capabilities within the FDF for supporting critical launch and early orbit navigation activities, especially challenging for constellation missions.

  10. Space-time clusters of breast cancer using residential histories: A Danish case–control study

    PubMed Central

    2014-01-01

    Background A large proportion of breast cancer cases are thought related to environmental factors. Identification of specific geographical areas with high risk (clusters) may give clues to potential environmental risk factors. The aim of this study was to investigate whether clusters of breast cancer existed in space and time in Denmark, using 33 years of residential histories. Methods We conducted a population-based case–control study of 3138 female cases from the Danish Cancer Registry, diagnosed with breast cancer in 2003 and two independent control groups of 3138 women each, randomly selected from the Civil Registration System. Residential addresses of cases and controls from 1971 to 2003 were collected from the Civil Registration System and geo-coded. Q-statistics were used to identify space-time clusters of breast cancer. All analyses were carried out with both control groups, and for 66% of the study population we also conducted analyses adjusted for individual reproductive factors and area-level socioeconomic indicators. Results In the crude analyses a cluster in the northern suburbs of Copenhagen was consistently found throughout the study period (1971–2003) with both control groups. When analyses were adjusted for individual reproductive factors and area-level socioeconomic indicators, the cluster area became smaller and less evident. Conclusions The breast cancer cluster area that persisted after adjustment might be explained by factors that were not accounted for such as alcohol consumption and use of hormone replacement therapy. However, we cannot exclude environmental pollutants as a contributing cause, but no pollutants specific to this area seem obvious. PMID:24725434

  11. Time Development in the Early History of Social Networks: Link Stabilization, Group Dynamics, and Segregation

    PubMed Central

    Bruun, Jesper; Bearden, Ian G.

    2014-01-01

    Studies of the time development of empirical networks usually investigate late stages where lasting connections have already stabilized. Empirical data on early network history are rare but needed for a better understanding of how social network topology develops in real life. Studying students who are beginning their studies at a university with no or few prior connections to each other offers a unique opportunity to investigate the formation and early development of link patterns and community structure in social networks. During a nine week introductory physics course, first year physics students were asked to identify those with whom they communicated about problem solving in physics during the preceding week. We use these students' self reports to produce time dependent student interaction networks. We investigate these networks to elucidate possible effects of different student attributes in early network formation. Changes in the weekly number of links show that while roughly half of all links change from week to week, students also reestablish a growing number of links as they progress through their first weeks of study. Using the Infomap community detection algorithm, we show that the networks exhibit community structure, and we use non-network student attributes, such as gender and end-of-course grade to characterize communities during their formation. Specifically, we develop a segregation measure and show that students structure themselves according to gender and pre-organized sections (in which students engage in problem solving and laboratory work), but not according to end-of-coure grade. Alluvial diagrams of consecutive weeks' communities show that while student movement between groups are erratic in the beginnning of their studies, they stabilize somewhat towards the end of the course. Taken together, the analyses imply that student interaction networks stabilize quickly and that students establish collaborations based on who is immediately

  12. Pressure--Temperature--Time (P--T--t) Histories of Orogenic Belts

    NASA Astrophysics Data System (ADS)

    Thompson, A. B.; Ridley, J. R.

    1987-01-01

    Thermal modelling shows that a cycle of crustal thickening and erosion reproduces many of the characteristics of medium-pressure metamorphic terranes. In contrast, the structural and metamorphic features of high-pressure terranes suggest rapid exhumation, possibly tectonically as fault-bounded blocks. Low-pressure metamorphism requires an augmented heat supply. Such terranes are characterized by granite--gneiss domes, and evidence of crustal extension, and hence may be the result of the mechanically likely orogenic sequence of early thickening followed by extension. Whether earlier isograd sequences are extended, condensed, or reset depends upon the relative rates of deformation and thermal relaxation, and when the deformation occurs relative to the thermal peak of metamorphism. Detailed determinations of relations between deformation events and metamorphism is made difficult by the contrast between continuous metamorphic evolution and short time-span deformation events. Combined microstructural and geochronological studies, together with a consideration of the distribution of isograds will give most information on complex, polymetamorphic histories, and allow distinction between regional and local features, especially those due to differential uplift. Considerations of rates of heat flow within the crust indicate how isotherms evolve in response to tectonic events, and how isograd distribution will relate to local and regional structures. Important controls are the relative rates of deformation and thermal relaxation, and whether the deformation predates, is synchronous with, or postdates the metamorphic peak. Only tectonic events close to or after the metainorphic peak, result in deformed isograds; at the peak, in areas where deformation induces local cooling; after the peak isograd sequences may be folded and expanded or condensed by crustal thickening or thinning. As repeated Information on orogenic development during the cooling and uplift stage of

  13. Rank-based inference for the accelerated failure time model in the presence of interval censored data

    NASA Astrophysics Data System (ADS)

    Karimi, Mostafa; Ibrahim, Noor Akma; Bakar, Mohd. Rizam Abu; Arasan, Jayanthi

    2016-06-01

    Semiparametric analysis and rank-based inference for the accelerated failure time model are complicated in the presence of interval censored data. The main difficulty with the existing rank-based methods is that they involve estimating functions with the possibility of multiple roots. In this paper a class of asymptotically normal rank estimators is developed which can be aquired via linear programming for estimating the parameters of the model, and a two-step iterative algorithm is introduce for solving the estimating equations. The proposed inference procedures are assessed through a real example.

  14. Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Oral Presentation

    SciTech Connect

    Araya, Million

    2015-08-25

    SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hz 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervalswhere the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.

  15. Complete cosmic scenario from inflation to late time acceleration: Nonequilibrium thermodynamics in the context of particle creation

    NASA Astrophysics Data System (ADS)

    Chakraborty, Subenoy; Saha, Subhajit

    2014-12-01

    The paper deals with the mechanism of particle creation in the framework of irreversible thermodynamics. The second order nonequilibrium thermodynamical prescription of Israel and Stewart has been presented with particle creation rate, treated as the dissipative effect. In the background of a flat Friedmann-Robertson-Walker (FRW) model, we assume the nonequilibrium thermodynamical process to be isentropic so that the entropy per particle does not change and consequently the dissipative pressure can be expressed linearly in terms of the particle creation rate. Here the dissipative pressure behaves as a dynamical variable having a nonlinear inhomogeneous evolution equation and the entropy flow vector satisfies the second law of thermodynamics. Further, using the Friedmann equations and by proper choice of the particle creation rate as a function of the Hubble parameter, it is possible to show (separately) a transition from the inflationary phase to the radiation era and also from the matter dominated era to late time acceleration. Also, in analogy to analytic continuation, it is possible to show a continuous cosmic evolution from inflation to late time acceleration by adjusting the parameters. It is found that in the de Sitter phase, the comoving entropy increases exponentially with time, keeping entropy per particle unchanged. Subsequently, the above cosmological scenarios have been described from a field theoretic point of view by introducing a scalar field having self-interacting potential. Finally, we make an attempt to show the cosmological phenomenon of particle creation as Hawking radiation, particularly during the inflationary era.

  16. Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Final Paper

    SciTech Connect

    Araya, Million

    2015-08-21

    SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hz 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervals-where the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.

  17. Time-dependent Acceleration of Pickup Ions at The Heliospheric Termination Shock

    SciTech Connect

    Le Roux, J. A.

    2008-08-25

    It is discussed how a time-dependent focused transport model, using a time series of shock obliquities at the termination shock based on Voyager 1 observations to model magnetic field-line random walk, can reproduce observational features of energetic ions at the termination shock and in the heliosheath which is beyond the scope of standard cosmic-ray transport models.

  18. THE MATRYOSHKA RUN. II. TIME-DEPENDENT TURBULENCE STATISTICS, STOCHASTIC PARTICLE ACCELERATION, AND MICROPHYSICS IMPACT IN A MASSIVE GALAXY CLUSTER

    SciTech Connect

    Miniati, Francesco

    2015-02-10

    We use the Matryoshka run to study the time-dependent statistics of structure-formation-driven turbulence in the intracluster medium of a 10{sup 15} M {sub ☉} galaxy cluster. We investigate the turbulent cascade in the inner megaparsec for both compressional and incompressible velocity components. The flow maintains approximate conditions of fully developed turbulence, with departures thereof settling in about an eddy-turnover time. Turbulent velocity dispersion remains above 700 km s{sup –1} even at low mass accretion rate, with the fraction of compressional energy between 10% and 40%. The normalization and the slope of the compressional turbulence are susceptible to large variations on short timescales, unlike the incompressible counterpart. A major merger occurs around redshift z ≅ 0 and is accompanied by a long period of enhanced turbulence, ascribed to temporal clustering of mass accretion related to spatial clustering of matter. We test models of stochastic acceleration by compressional modes for the origin of diffuse radio emission in galaxy clusters. The turbulence simulation model constrains an important unknown of this complex problem and brings forth its dependence on the elusive microphysics of the intracluster plasma. In particular, the specifics of the plasma collisionality and the dissipation physics of weak shocks affect the cascade of compressional modes with strong impact on the acceleration rates. In this context radio halos emerge as complex phenomena in which a hierarchy of processes acting on progressively smaller scales are at work. Stochastic acceleration by compressional modes implies statistical correlation of radio power and spectral index with merging cores distance, both testable in principle with radio surveys.

  19. Hard X-ray time profiles and acceleration processes in large solar flares

    NASA Technical Reports Server (NTRS)

    Bai, T.; Ramaty, R.

    1979-01-01

    The hard X-ray time profiles of the (1972) August 4 and 7 flares are investigated, taking into account a comparison of the time profiles of different energy channels. It is shown that for these flares the temporal features of the intensity profiles of higher energy channels are delayed with respect to those of channel 1. The delay time gradually increases to approximately 5 sec as the channel number increases from 1 to 5, and it jumps to approximately 15 sec for channels 6 and 7. A description is presented of a model in which the delay and other characteristics of the observed time profiles in channels 1-5 are self-consistently explained by the increase of the electron energy loss time with electron energy.

  20. A drug-induced accelerated senescence (DIAS) is a possibility to study aging in time lapse.

    PubMed

    Alili, Lirija; Diekmann, Johanna; Giesen, Melanie; Holtkötter, Olaf; Brenneisen, Peter

    2014-06-01

    Currently, the oxidative stress (or free radical) theory of aging is the most popular explanation of how aging occurs at the molecular level. Accordingly, a stress-induced senescence-like phenotype of human dermal fibroblasts can be induced in vitro by the exposure of human diploid fibroblasts to subcytotoxic concentrations of hydrogen peroxide. However, several biomarkers of replicative senescence e.g. cell cycle arrest and enlarged morphology are abrogated 14 days after treatment, indicating that reactive oxygen species (ROS) rather acts as a trigger for short-term senescence (1-3 days) than being responsible for the maintenance of the senescence-like phenotype. Further, DNA-damaging factors are discussed resulting in a permanent senescent cell type. To induce long-term premature senescence and to understand the molecular alterations occurring during the aging process, we analyzed mitomycin C (MMC) as an alkylating DNA-damaging agent and ROS producer. Human dermal fibroblasts (HDF), used as model for skin aging, were exposed to non-cytotoxic concentrations of MMC and analyzed for potential markers of cellular aging, for example enlarged morphology, activity of senescence-associated-ß-galactosidase, cell cycle arrest, increased ROS production and MMP1-activity, which are well-documented for HDF in replicative senescence. Our data show that mitomycin C treatment results in a drug-induced accelerated senescence (DIAS) with long-term expression of senescence markers, demonstrating that a combination of different susceptibility factors, here ROS and DNA alkylation, are necessary to induce a permanent senescent cell type.

  1. Full time-resolved diffuse fluorescence tomography accelerated with parallelized Fourier-series truncated diffusion approximation.

    PubMed

    Yi, Xi; Wang, Bingyuan; Wan, Wenbo; Wang, Yihan; Zhang, Yanqi; Zhao, Huijuan; Gao, Feng

    2015-05-01

    Of the three measurement schemes established for diffuse fluorescence tomography (DFT), the time-domain scheme is well known to provide the richest information about the distribution of the targeting fluorophore in living tissues. However, the explicit use of the full time-resolved data usually leads to a considerably lengthy time for image reconstruction, limiting its applications to three-dimensional or small-volume imaging. To cope with the adversity, we propose herein a computationally efficient scheme for DFT image reconstruction where the time-dependent photon density is expanded to a Fourier-series and calculated by solving the independent frequency-domain diffusion equations at multiple sampling frequencies with the support of a combined multicore CPU-based coarse-grain and multithread GPU-based fine-grain parallelization strategy. With such a parallelized Fourier-series truncated diffusion approximation, both the time- and frequency-domain inversion procedures are developed and validated for their effectiveness and accuracy using simulative and phantom experiments. The results show that the proposed method can generate reconstructions comparable to the explicit time-domain scheme, with significantly reduced computational time.

  2. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration.

    PubMed

    Brandi, F; Giammanco, F; Conti, F; Sylla, F; Lambert, G; Gizzi, L A

    2016-08-01

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 10(19) cm(-3) range well suited for LWFA. PMID:27587174

  3. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration.

    PubMed

    Brandi, F; Giammanco, F; Conti, F; Sylla, F; Lambert, G; Gizzi, L A

    2016-08-01

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 10(19) cm(-3) range well suited for LWFA.

  4. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration

    NASA Astrophysics Data System (ADS)

    Brandi, F.; Giammanco, F.; Conti, F.; Sylla, F.; Lambert, G.; Gizzi, L. A.

    2016-08-01

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 1019 cm-3 range well suited for LWFA.

  5. Graphics processing unit-accelerated real-time compressive sensing spectral domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Xu, Daguang; Huang, Yong; Kang, Jin U.

    2015-03-01

    In this paper, we systematically demonstrate two real-time CS SD OCT systems based on a conventional desktop having three GPUs. The first one takes fast Fourier transform (FFT) as the sensing technique and under-sampled linear wavenumber spectral sampling as input data, while the second one uses non-uniform fast Fourier transform (NUFFT) and under-sampled nonlinear wavenumber spectral sampling, respectively. The maximum reconstruction speed of 72k and 33.5k A-line/s were achieved for these two systems, respectively, with A-scan size 2048. It is >100 times faster than the C++ implementation and >400 times faster than the MATLAB implementation. Finally, we present real-time dispersion compensated image reconstruction for both systems.

  6. Towards the theory of regular accelerating Universe in Riemann-Cartan space-time

    NASA Astrophysics Data System (ADS)

    Minkevich, A. V.

    2016-01-01

    The problems of modern cosmology and attempts of its solution are considered. The applying of gravitation theory in the Riemann-Cartan space-time as the most natural generalization of Einstein gravitation theory in order to solve the principal cosmological problems is discussed. The gravitation theory in the Riemann-Cartan space-time leading to the solution of the problem of cosmological singularity and dark energy problem is analyzed.

  7. Graphic processing unit accelerated real-time partially coherent beam generator

    NASA Astrophysics Data System (ADS)

    Ni, Xiaolong; Liu, Zhi; Chen, Chunyi; Jiang, Huilin; Fang, Hanhan; Song, Lujun; Zhang, Su

    2016-07-01

    A method of using liquid-crystals (LCs) to generate a partially coherent beam in real-time is described. An expression for generating a partially coherent beam is given and calculated using a graphic processing unit (GPU), i.e., the GeForce GTX 680. A liquid-crystal on silicon (LCOS) with 256 × 256 pixels is used as the partially coherent beam generator (PCBG). An optimizing method with partition convolution is used to improve the generating speed of our LC PCBG. The total time needed to generate a random phase map with a coherence width range from 0.015 mm to 1.5 mm is less than 2.4 ms for calculation and readout with the GPU; adding the time needed for the CPU to read and send to LCOS with the response time of the LC PCBG, the real-time partially coherent beam (PCB) generation frequency of our LC PCBG is up to 312 Hz. To our knowledge, it is the first real-time partially coherent beam generator. A series of experiments based on double pinhole interference are performed. The result shows that to generate a laser beam with a coherence width of 0.9 mm and 1.5 mm, with a mean error of approximately 1%, the RMS values needed 0.021306 and 0.020883 and the PV values required 0.073576 and 0.072998, respectively.

  8. Unifying phantom inflation with late-time acceleration: scalar phantom-non-phantom transition model and generalized holographic dark energy

    NASA Astrophysics Data System (ADS)

    Nojiri, Shin'ichi; Odintsov, Sergei D.

    2006-08-01

    The unifying approach to early-time and late-time universe based on phantom cosmology is proposed. We consider gravity-scalar system which contains usual potential and scalar coupling function in front of kinetic term. As a result, the possibility of phantom-non-phantom transition appears in such a way that universe could have effectively phantom equation of state at early time as well as at late time. In fact, the oscillating universe may have several phantom and non-phantom phases. Role in each of two phase and can be absorbed into the redefinition of the scalar field. Right on the transition point, however, the factor cannot be absorbed into the redefinition and play the role to connect two phases smoothly. Holographic dark energy where infrared cutoff is identified with combination of FRW parameters: Hubble constant, particle and future horizons, cosmological constant and universe life-time (if finite). Depending on the specific choice of the model the number of interesting effects occur: the possibility to solve the coincidence problem, crossing of phantom divide and unification of early-time inflationary and late-time accelerating phantom universe. The bound for holographic entropy which decreases in phantom era is also discussed.

  9. Solution of the equation of heat conduction with time dependent sources: Programmed application to planetary thermal history

    NASA Technical Reports Server (NTRS)

    Conel, J. E.

    1975-01-01

    A computer program (Program SPHERE) solving the inhomogeneous equation of heat conduction with radiation boundary condition on a thermally homogeneous sphere is described. The source terms are taken to be exponential functions of the time. Thermal properties are independent of temperature. The solutions are appropriate to studying certain classes of planetary thermal history. Special application to the moon is discussed.

  10. Forever Outsiders: Jews and History from Ancient Times to August 1935. Holocaust Series, Book 1. First Edition.

    ERIC Educational Resources Information Center

    Altman, Linda Jacobs

    There are eight volumes in this series on the Holocaust. Volumes 1-6 recount the history of the Jewish people in various year groupings: (1) "Ancient Times to August 1935"; (2) "September 1935 to December 1938"; (3) "January 1939 to December 1941"; (4) "January 1942 to June 1943"; (5) "July 1943 to April 1945"; (6) "May 1945 and After." Volumes 7…

  11. Applicability of time-to-failure analysis to accelerated strain before earthquakes and volcanic eruptions

    NASA Astrophysics Data System (ADS)

    Main, Ian G.

    1999-12-01

    We examine quantitatively the ranges of applicability of the equation Ω=A+B[1-t/tf]m for predicting `system-sized' failure times tf in the Earth. In applications Ω is a proxy measure for strain or crack length, and A, B and the index m are model parameters determined by curve fitting. We consider constitutive rules derived from (a) Charles' law for subcritical crack growth; (b) Voight's equation; and (c) a simple percolation model, and show in each case that this equation holds only when m<0. When m>0, the general solution takes the form Ω=A+B[1+t/T]m, where T is a positive time constant, and no failure time can be defined. Reported values for volcanic precursors based on rate data are found to be within the range of applicability of time-to-failure analysis (m<0). The same applies to seismic moment release before earthquakes, at the expense of poor retrospective predictability of the time of the a posteriori-defined main shock. In contrast, reported values based on increasing cumulative Benioff strain occur in the region where a system-sized failure time cannot be defined (m>0 commonly m~0.3). We conclude on physical grounds that cumulative seismic moment is preferred as the most direct measure of seismic strain. If cumulative Benioff strain is to be retained on empirical grounds, then it is important that these data either be re-examined with the independent constraint m<0, or that for the case 0time-integration of cumulative data be applied, of the form ΣΩ=At+B'{1-[1-t/tf]m+1}.

  12. Magnetospheric Multiscale Satellite Observations of Parallel Electron Acceleration in Magnetic Field Reconnection by Fermi Reflection from Time Domain Structures.

    PubMed

    Mozer, F S; Agapitov, O A; Artemyev, A; Burch, J L; Ergun, R E; Giles, B L; Mourenas, D; Torbert, R B; Phan, T D; Vasko, I

    2016-04-01

    The same time domain structures (TDS) have been observed on two Magnetospheric Multiscale Satellites near Earth's dayside magnetopause. These TDS, traveling away from the X line along the magnetic field at 4000  km/s, accelerated field-aligned ∼5  eV electrons to ∼200  eV by a single Fermi reflection of the electrons by these overtaking barriers. Additionally, the TDS contained both positive and negative potentials, so they were a mixture of electron holes and double layers. They evolve in ∼10  km of space or 7 ms of time and their spatial scale size is 10-20 km, which is much larger than the electron gyroradius (<1  km) or the electron inertial length (4 km at the observation point, less nearer the X line). PMID:27104714

  13. Future evolution and finite-time singularities in F(R) gravity unifying inflation and cosmic acceleration

    SciTech Connect

    Nojiri, Shin'ichi; Odintsov, Sergei D.

    2008-08-15

    We study the future evolution of quintessence/phantom-dominated epoch in modified F(R) gravity which unifies the early-time inflation with late-time acceleration and which is consistent with observational tests. Using the reconstruction technique it is demonstrated that there are models where any known (big rip, II, III, or IV type) singularity may classically occur. From another side, in Einstein frame (scalar-tensor description) only IV type singularity occurs. Near the singularity the classical description breaks up, and it is demonstrated that quantum effects act against the singularity and may prevent its appearance. The realistic F(R) gravity which is future singularity free is proposed. We point out that additional modification of any F(R) gravity by the terms relevant at the early universe is possible, in such a way that future singularity does not occur even classically.

  14. The time dependent propensity function for acceleration of spatial stochastic simulation of reaction-diffusion systems

    NASA Astrophysics Data System (ADS)

    Fu, Jin; Wu, Sheng; Li, Hong; Petzold, Linda R.

    2014-10-01

    The inhomogeneous stochastic simulation algorithm (ISSA) is a fundamental method for spatial stochastic simulation. However, when diffusion events occur more frequently than reaction events, simulating the diffusion events by ISSA is quite costly. To reduce this cost, we propose to use the time dependent propensity function in each step. In this way we can avoid simulating individual diffusion events, and use the time interval between two adjacent reaction events as the simulation stepsize. We demonstrate that the new algorithm can achieve orders of magnitude efficiency gains over widely-used exact algorithms, scales well with increasing grid resolution, and maintains a high level of accuracy.

  15. The Time Dependent Propensity Function for Acceleration of Spatial Stochastic Simulation of Reaction-Diffusion Systems

    PubMed Central

    Wu, Sheng; Li, Hong; Petzold, Linda R.

    2015-01-01

    The inhomogeneous stochastic simulation algorithm (ISSA) is a fundamental method for spatial stochastic simulation. However, when diffusion events occur more frequently than reaction events, simulating the diffusion events by ISSA is quite costly. To reduce this cost, we propose to use the time dependent propensity function in each step. In this way we can avoid simulating individual diffusion events, and use the time interval between two adjacent reaction events as the simulation stepsize. We demonstrate that the new algorithm can achieve orders of magnitude efficiency gains over widely-used exact algorithms, scales well with increasing grid resolution, and maintains a high level of accuracy. PMID:26609185

  16. The time dependent propensity function for acceleration of spatial stochastic simulation of reaction–diffusion systems

    SciTech Connect

    Fu, Jin; Wu, Sheng; Li, Hong; Petzold, Linda R.

    2014-10-01

    The inhomogeneous stochastic simulation algorithm (ISSA) is a fundamental method for spatial stochastic simulation. However, when diffusion events occur more frequently than reaction events, simulating the diffusion events by ISSA is quite costly. To reduce this cost, we propose to use the time dependent propensity function in each step. In this way we can avoid simulating individual diffusion events, and use the time interval between two adjacent reaction events as the simulation stepsize. We demonstrate that the new algorithm can achieve orders of magnitude efficiency gains over widely-used exact algorithms, scales well with increasing grid resolution, and maintains a high level of accuracy.

  17. PROBING DYNAMICS OF ELECTRON ACCELERATION WITH RADIO AND X-RAY SPECTROSCOPY, IMAGING, AND TIMING IN THE 2002 APRIL 11 SOLAR FLARE

    SciTech Connect

    Fleishman, Gregory D.; Nita, Gelu M.; Gary, Dale E.; Kontar, Eduard P.

    2013-05-10

    Based on detailed analysis of radio and X-ray observations of a flare on 2002 April 11 augmented by realistic three-dimensional modeling, we have identified a radio emission component produced directly at the flare acceleration region. This acceleration region radio component has distinctly different (1) spectrum, (2) light curves, (3) spatial location, and, thus, (4) physical parameters from those of the separately identified trapped or precipitating electron components. To derive evolution of physical parameters of the radio sources we apply forward fitting of the radio spectrum time sequence with the gyrosynchrotron source function with five to six free parameters. At the stage when the contribution from the acceleration region dominates the radio spectrum, the X-ray- and radio-derived electron energy spectral indices agree well with each other. During this time the maximum energy of the accelerated electron spectrum displays a monotonic increase with time from {approx}300 keV to {approx}2 MeV over roughly one minute duration indicative of an acceleration process in the form of growth of the power-law tail; the fast electron residence time in the acceleration region is about 2-4 s, which is much longer than the time of flight and so requires a strong diffusion mode there to inhibit free-streaming propagation. The acceleration region has a relatively strong magnetic field, B {approx} 120 G, and a low thermal density, n{sub e} {approx}< 2 Multiplication-Sign 10{sup 9} cm{sup -3}. These acceleration region properties are consistent with a stochastic acceleration mechanism.

  18. GPU-accelerated Modeling and Element-free Reverse-time Migration with Gauss Points Partition

    NASA Astrophysics Data System (ADS)

    Zhen, Z.; Jia, X.

    2014-12-01

    Element-free method (EFM) has been applied to seismic modeling and migration. Compared with finite element method (FEM) and finite difference method (FDM), it is much cheaper and more flexible because only the information of the nodes and the boundary of the study area are required in computation. In the EFM, the number of Gauss points should be consistent with the number of model nodes; otherwise the accuracy of the intermediate coefficient matrices would be harmed. Thus when we increase the nodes of velocity model in order to obtain higher resolution, we find that the size of the computer's memory will be a bottleneck. The original EFM can deal with at most 81×81 nodes in the case of 2G memory, as tested by Jia and Hu (2006). In order to solve the problem of storage and computation efficiency, we propose a concept of Gauss points partition (GPP), and utilize the GPUs to improve the computation efficiency. Considering the characteristics of the Gaussian points, the GPP method doesn't influence the propagation of seismic wave in the velocity model. To overcome the time-consuming computation of the stiffness matrix (K) and the mass matrix (M), we also use the GPUs in our computation program. We employ the compressed sparse row (CSR) format to compress the intermediate sparse matrices and try to simplify the operations by solving the linear equations with the CULA Sparse's Conjugate Gradient (CG) solver instead of the linear sparse solver 'PARDISO'. It is observed that our strategy can significantly reduce the computational time of K and Mcompared with the algorithm based on CPU. The model tested is Marmousi model. The length of the model is 7425m and the depth is 2990m. We discretize the model with 595x298 nodes, 300x300 Gauss cells and 3x3 Gauss points in each cell. In contrast to the computational time of the conventional EFM, the GPUs-GPP approach can substantially improve the efficiency. The speedup ratio of time consumption of computing K, M is 120 and the

  19. Human life history evolution explains dissociation between the timing of tooth eruption and peak rates of root growth.

    PubMed

    Dean, M Christopher; Cole, Tim J

    2013-01-01

    We explored the relationship between growth in tooth root length and the modern human extended period of childhood. Tooth roots provide support to counter chewing forces and so it is advantageous to grow roots quickly to allow teeth to erupt into function as early as possible. Growth in tooth root length occurs with a characteristic spurt or peak in rate sometime between tooth crown completion and root apex closure. Here we show that in Pan troglodytes the peak in root growth rate coincides with the period of time teeth are erupting into function. However, the timing of peak root velocity in modern humans occurs earlier than expected and coincides better with estimates for tooth eruption times in Homo erectus. With more time to grow longer roots prior to eruption and smaller teeth that now require less support at the time they come into function, the root growth spurt no longer confers any advantage in modern humans. We suggest that a prolonged life history schedule eventually neutralised this adaptation some time after the appearance of Homo erectus. The root spurt persists in modern humans as an intrinsic marker event that shows selection operated, not primarily on tooth tissue growth, but on the process of tooth eruption. This demonstrates the overarching influence of life history evolution on several aspects of dental development. These new insights into tooth root growth now provide an additional line of enquiry that may contribute to future studies of more recent life history and dietary adaptations within the genus Homo. PMID:23342167

  20. Human life history evolution explains dissociation between the timing of tooth eruption and peak rates of root growth.

    PubMed

    Dean, M Christopher; Cole, Tim J

    2013-01-01

    We explored the relationship between growth in tooth root length and the modern human extended period of childhood. Tooth roots provide support to counter chewing forces and so it is advantageous to grow roots quickly to allow teeth to erupt into function as early as possible. Growth in tooth root length occurs with a characteristic spurt or peak in rate sometime between tooth crown completion and root apex closure. Here we show that in Pan troglodytes the peak in root growth rate coincides with the period of time teeth are erupting into function. However, the timing of peak root velocity in modern humans occurs earlier than expected and coincides better with estimates for tooth eruption times in Homo erectus. With more time to grow longer roots prior to eruption and smaller teeth that now require less support at the time they come into function, the root growth spurt no longer confers any advantage in modern humans. We suggest that a prolonged life history schedule eventually neutralised this adaptation some time after the appearance of Homo erectus. The root spurt persists in modern humans as an intrinsic marker event that shows selection operated, not primarily on tooth tissue growth, but on the process of tooth eruption. This demonstrates the overarching influence of life history evolution on several aspects of dental development. These new insights into tooth root growth now provide an additional line of enquiry that may contribute to future studies of more recent life history and dietary adaptations within the genus Homo.

  1. CUDA Fortran acceleration for the finite-difference time-domain method

    NASA Astrophysics Data System (ADS)

    Hadi, Mohammed F.; Esmaeili, Seyed A.

    2013-05-01

    A detailed description of programming the three-dimensional finite-difference time-domain (FDTD) method to run on graphical processing units (GPUs) using CUDA Fortran is presented. Two FDTD-to-CUDA thread-block mapping designs are investigated and their performances compared. Comparative assessment of trade-offs between GPU's shared memory and L1 cache is also discussed. This presentation is for the benefit of FDTD programmers who work exclusively with Fortran and are reluctant to port their codes to C in order to utilize GPU computing. The derived CUDA Fortran code is compared with an optimized CPU version that runs on a workstation-class CPU to present a realistic GPU to CPU run time comparison and thus help in making better informed investment decisions on FDTD code redesigns and equipment upgrades. All analyses are mirrored with CUDA C simulations to put in perspective the present state of CUDA Fortran development.

  2. GPU-accelerated real-time IR smoke screen simulation and assessment of its obscuration

    NASA Astrophysics Data System (ADS)

    Wu, Xin; Zhang, Jian-qi; Huang, Xi; Liu, De-lian

    2012-01-01

    With the growing demand for the Battlefield Environment Simulation (BES), IR smoke screen, which is computationally expensive and absolutely indispensable, should be modeled true to life and correct in its thermal radiation characteristics. This paper analyzes the features of an IR smoke screen, and represents an IR smoke screen model based on light extinction, particle dispersion and temperature attenuation, which is calculated by GPU and rendered to screen in real time. Thus a method considering both the real-life in profile and the real-time in efficiency is presented. Additionally, the comparison between the simulated results and the measured data is made to verify the correctness of the smoke screen's obscuration, which illustrates the effect of its interference feature in an infrared scene.

  3. Accelerating Time-Varying Hardware Volume Rendering Using TSP Trees and Color-Based Error Metrics

    NASA Technical Reports Server (NTRS)

    Ellsworth, David; Chiang, Ling-Jen; Shen, Han-Wei; Kwak, Dochan (Technical Monitor)

    2000-01-01

    This paper describes a new hardware volume rendering algorithm for time-varying data. The algorithm uses the Time-Space Partitioning (TSP) tree data structure to identify regions within the data that have spatial or temporal coherence. By using this coherence, the rendering algorithm can improve performance when the volume data is larger than the texture memory capacity by decreasing the amount of textures required. This coherence can also allow improved speed by appropriately rendering flat-shaded polygons instead of textured polygons, and by not rendering transparent regions. To reduce the polygonization overhead caused by the use of the hierarchical data structure, we introduce an optimization method using polygon templates. The paper also introduces new color-based error metrics, which more accurately identify coherent regions compared to the earlier scalar-based metrics. By showing experimental results from runs using different data sets and error metrics, we demonstrate that the new methods give substantial improvements in volume rendering performance.

  4. Accelerating the Customer-Driven Microgrid Through Real-Time Digital Simulation

    SciTech Connect

    I. Leonard; T. Baldwin; M. Sloderbeck

    2009-07-01

    Comprehensive design and testing of realistic customer-driven microgrids requires a high performance simulation platform capable of incorporating power system and control models with external hardware systems. Traditional non real-time simulation is unable to fully capture the level of detail necessary to expose real-world implementation issues. With a real-time digital simulator as its foundation, a high-fidelity simulation environment that includes a robust electrical power system model, advanced control architecture, and a highly adaptable communication network is introduced. Hardware-in-the-loop implementation approaches for the hardware-based control and communication systems are included. An overview of the existing power system model and its suitability for investigation of autonomous island formation within the microgrid is additionally presented. Further test plans are also documented.

  5. Particle acceleration due to shocks in the interplanetary field: High time resolution data and simulation results

    NASA Technical Reports Server (NTRS)

    Kessel, R. L.; Armstrong, T. P.; Nuber, R.; Bandle, J.

    1985-01-01

    Data were examined from two experiments aboard the Explorer 50 (IMP 8) spacecraft. The Johns Hopkins University/Applied Lab Charged Particle Measurement Experiment (CPME) provides 10.12 second resolution ion and electron count rates as well as 5.5 minute or longer averages of the same, with data sampled in the ecliptic plane. The high time resolution of the data allows for an explicit, point by point, merging of the magnetic field and particle data and thus a close examination of the pre- and post-shock conditions and particle fluxes associated with large angle oblique shocks in the interplanetary field. A computer simulation has been developed wherein sample particle trajectories, taken from observed fluxes, are allowed to interact with a planar shock either forward or backward in time. One event, the 1974 Day 312 shock, is examined in detail.

  6. Continuities and Discontinuities in the Life Histories of Teacher Educators in Changing Times

    ERIC Educational Resources Information Center

    O'Brien, Maeve; Furlong, Catherine

    2015-01-01

    Although teacher education has undergone radical reforms in many jurisdictions, who teacher educators are, their lives, and their work, continue to be a somewhat underexplored area internationally, while remaining a "secret garden" in the Irish context. In order to address this lacuna in Irish research, this paper adopts a life history,…

  7. "Our Journey through Time": An Oral History Project Carried out by Young People with Learning Disabilities

    ERIC Educational Resources Information Center

    Bentley, Sarah; Nicholls, Rickie; Price, Maxine; Wilkinson, Aaron; Purcell, Matthew; Woodhall, Martin; Walmsley, Jan

    2011-01-01

    We are five young people with learning disabilities who found out about the history of hospitals for people with learning disabilities in our area, and made a film about the project. The project taught us what life had been like for some people with learning disabilities only 30 years ago. It was very different to our lives; we have more choice,…

  8. [THE HISTORY OF SKIN GRAFTING, ANCIENT TIMES AND CIVILIZATIONS. THE FIRST MENTIONS].

    PubMed

    Sokolov, V A; Skvortsov, Yu R; Tarasenku, M Yu

    2015-01-01

    The article dials with the history of medicine practiced by the first civilizations. The facts of discovery and analysis of ancient medical treatises by modern researchers are reported. Special emphasis is laid on the achievements of medical practitioners in Ancient Egypt and India that promoted the development of operative treatment including skin grafting. PMID:26168607

  9. [THE HISTORY OF SKIN GRAFTING, ANCIENT TIMES AND CIVILIZATIONS. THE FIRST MENTIONS].

    PubMed

    Sokolov, V A; Skvortsov, Yu R; Tarasenku, M Yu

    2015-01-01

    The article dials with the history of medicine practiced by the first civilizations. The facts of discovery and analysis of ancient medical treatises by modern researchers are reported. Special emphasis is laid on the achievements of medical practitioners in Ancient Egypt and India that promoted the development of operative treatment including skin grafting.

  10. Life and Times of John H. Hickcox: Government Publications History Revisited.

    ERIC Educational Resources Information Center

    Stimson, Nancy F.; Nobunaga, Wendy Y.

    1995-01-01

    In 1885, John H. Hickcox published a catalog that alerted the public to the availability of recent federal government publications; this catalog immediately preceded establishment of a government-published catalog, of which he was appointed the first compiler. Hickcox's work history included writing, editing, and cataloging positions. (AEF)

  11. Teaching Adult Education History in a Time of Uncertainty and Hope

    ERIC Educational Resources Information Center

    Brown, Tony

    2010-01-01

    Adult education's continuing purpose has been questioned by writers for over twenty years and today the re-organisation and closure of some University departments brings this issue to the fore. This paper takes up the theme of really useful knowledge in a changing world from the standpoint of teaching adult education history to graduate students.…

  12. Storm time impulsive enhancements of energetic oxygen due to adiabatic acceleration of preexisting warm oxygen in the inner magnetosphere

    NASA Astrophysics Data System (ADS)

    Keika, Kunihiro; Seki, Kanako; Nosé, Masahito; Machida, Shinobu; Miyoshi, Yoshizumi; Lanzerotti, Louis J.; Mitchell, Donald G.; Gkioulidou, Matina; Turner, Drew; Spence, Harlan; Larsen, Brian A.

    2016-08-01

    We examine enhancements of energetic (>50 keV) oxygen ions observed by the Radiation Belt Storm Probes Ion Composition Experiment (RBSPICE) instrument on board the Van Allen Probes spacecraft in the inner magnetosphere (L ~ 6) at 22-23 h magnetic local time (MLT) during an injection event of the 6 June 2013 storm. Simultaneous observations by two Van Allen Probes spacecraft located close together (~0.5 RE) indicate that particle injections occurred in the premidnight sector (< ~24 h MLT). We also examine the evolution of the proton and oxygen energy spectra at L ~ 6 during the injection event. The spectral slope did not significantly change during the storm. The oxygen phase space density (PSD) was shifted toward higher PSD in a wide range of the first adiabatic invariant. The spectral evolution manifests the characteristics of adiabatic acceleration and density increase of oxygen ions. Warm (0.1-10 keV) oxygen measured by the Helium, Oxygen, Proton, and Electron (HOPE) instrument was enhanced prior to the storm mostly in magnetic field-aligned directions. The most reasonable scenario of this event is that warm oxygen ions that preexisted in the inner magnetosphere were picked up and adiabatically transported and accelerated by spatially localized, temporarily impulsive electric fields.

  13. Dynamic real-time 4D cardiac MDCT image display using GPU-accelerated volume rendering.

    PubMed

    Zhang, Qi; Eagleson, Roy; Peters, Terry M

    2009-09-01

    Intraoperative cardiac monitoring, accurate preoperative diagnosis, and surgical planning are important components of minimally-invasive cardiac therapy. Retrospective, electrocardiographically (ECG) gated, multidetector computed tomographical (MDCT), four-dimensional (3D + time), real-time, cardiac image visualization is an important tool for the surgeon in such procedure, particularly if the dynamic volumetric image can be registered to, and fused with the actual patient anatomy. The addition of stereoscopic imaging provides a more intuitive environment by adding binocular vision and depth cues to structures within the beating heart. In this paper, we describe the design and implementation of a comprehensive stereoscopic 4D cardiac image visualization and manipulation platform, based on the opacity density radiation model, which exploits the power of modern graphics processing units (GPUs) in the rendering pipeline. In addition, we present a new algorithm to synchronize the phases of the dynamic heart to clinical ECG signals, and to calculate and compensate for latencies in the visualization pipeline. A dynamic multiresolution display is implemented to enable the interactive selection and emphasis of volume of interest (VOI) within the entire contextual cardiac volume and to enhance performance, and a novel color and opacity adjustment algorithm is designed to increase the uniformity of the rendered multiresolution image of heart. Our system provides a visualization environment superior to noninteractive software-based implementations, but with a rendering speed that is comparable to traditional, but inferior quality, volume rendering approaches based on texture mapping. This retrospective ECG-gated dynamic cardiac display system can provide real-time feedback regarding the suspected pathology, function, and structural defects, as well as anatomical information such as chamber volume and morphology.

  14. Effect of bedrest and positive radial acceleration upon peripheral visual response time.

    NASA Technical Reports Server (NTRS)

    Haines, R. F.

    1972-01-01

    Attempt to determine if peripheral visual response time (RT) could be used as a reliable advanced predictor of +G sub z-related blackout or grayout. The relatively high luminance of the peripheral stimuli used in the experiments may account for the finding that peripheral RT was not sensitive to impending blackout or grayout. The relatively consistent mean RTs within subjects across test days in bed is probably due to the relatively constant response characteristics of the retina and to the high repeatability of the stimuli.

  15. Convergence acceleration for time-independent first-order PDE using optimal PNB-approximations

    SciTech Connect

    Holmgren, S.; Branden, H.

    1996-12-31

    We consider solving time-independent (steady-state) flow problems in 2D or 3D governed by hyperbolic or {open_quotes}almost hyperbolic{close_quotes} systems of partial differential equations (PDE). Examples of such PDE are the Euler and the Navier-Stokes equations. The PDE is discretized using a finite difference or finite volume scheme with arbitrary order of accuracy. If the matrix B describes the discretized differential operator and u denotes the approximate solution, the discrete problem is given by a large system of equations.

  16. Denoising NMR time-domain signal by singular-value decomposition accelerated by graphics processing units.

    PubMed

    Man, Pascal P; Bonhomme, Christian; Babonneau, Florence

    2014-01-01

    We present a post-processing method that decreases the NMR spectrum noise without line shape distortion. As a result the signal-to-noise (S/N) ratio of a spectrum increases. This method is called Cadzow enhancement procedure that is based on the singular-value decomposition of time-domain signal. We also provide software whose execution duration is a few seconds for typical data when it is executed in modern graphic-processing unit. We tested this procedure not only on low sensitive nucleus (29)Si in hybrid materials but also on low gyromagnetic ratio, quadrupole nucleus (87)Sr in reference sample Sr(NO3)2. Improving the spectrum S/N ratio facilitates the determination of T/Q ratio of hybrid materials. It is also applicable to simulated spectrum, resulting shorter simulation duration for powder averaging. An estimation of the number of singular values needed for denoising is also provided. PMID:24880899

  17. The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data

    PubMed Central

    Jewett, Ethan M.; Steinrücken, Matthias; Song, Yun S.

    2016-01-01

    Many approaches have been developed for inferring selection coefficients from time series data while accounting for genetic drift. These approaches have been motivated by the intuition that properly accounting for the population size history can significantly improve estimates of selective strengths. However, the improvement in inference accuracy that can be attained by modeling drift has not been characterized. Here, by comparing maximum likelihood estimates of selection coefficients that account for the true population size history with estimates that ignore drift by assuming allele frequencies evolve deterministically in a population of infinite size, we address the following questions: how much can modeling the population size history improve estimates of selection coefficients? How much can mis-inferred population sizes hurt inferences of selection coefficients? We conduct our analysis under the discrete Wright–Fisher model by deriving the exact probability of an allele frequency trajectory in a population of time-varying size and we replicate our results under the diffusion model. For both models, we find that ignoring drift leads to estimates of selection coefficients that are nearly as accurate as estimates that account for the true population history, even when population sizes are small and drift is high. This result is of interest because inference methods that ignore drift are widely used in evolutionary studies and can be many orders of magnitude faster than methods that account for population sizes. PMID:27550904

  18. Real-time thermal imaging of microwave accelerated metal-enhanced fluorescence (MAMEF) based assays on sapphire plates.

    PubMed

    Previte, Michael J R; Zhang, Yongxia; Aslan, Kadir; Geddes, Chris D

    2007-11-01

    In this paper, we describe an optical geometry that facilitates our further characterization of the temperature changes above silver island films (SiFs) on sapphire plates, when exposed to microwave radiation. Since sapphire transmits IR, we designed an optical scheme to capture real-time temperature images of a thin water film on sapphire plates with and without SiFs during the application of a short microwave pulse. Using this optical scheme, we can accurately determine the temperature profile of solvents in proximity to metal structures when exposed to microwave irradiation. We believe that this optical scheme will provide us with a basis for further studies in designing metal structures to further improve plasmonic-fluorescence clinical sensing applications, such as those used in microwave accelerated metal-enhanced fluorescence (MAMEF). PMID:17902038

  19. Increasing the multiscale/multiphysics capability of CAM-SE using implicit time integration and GPU accelerators

    NASA Astrophysics Data System (ADS)

    Archibald, R.; Evans, K. J.; Worley, P.; Norman, M. R.; Lott, A.; Salinger, A.; Woodward, C. S.

    2014-12-01

    The recent focus on regional refinement in the Community Atmosphere Model (CAM5) has created a strong need to develop time-stepping methods capable of accelerating throughput on high performance computing for climate dynamics across multiple spatial and temporal scales. This research is focused on developing implicit methods that can be executed at scale on GPU based machines. Efforts to port the scalable spectral element dynamical core to incorporate these developments is presented, including both 2D and 3D benchmark test case results. The current implicit solver and preconditioner implementations utilize a Fortran interface package within the Trilinos project, third party software that allows fully tested, optimized, and robust code with a suite of parameter options to be included a priori. Merging this coding strategy with GPU libraries will be discussed along with beneficial optimization gains and data structure requirements to evaluate Trilinos binded residual calculations on GPU processors.

  20. Divergence history of the Carpathian and smooth newts modelled in space and time.

    PubMed

    Zieliński, P; Nadachowska-Brzyska, K; Dudek, K; Babik, W

    2016-08-01

    Information about demographic history is essential for the understanding of the processes of divergence and speciation. Patterns of genetic variation within and between closely related species provide insights into the history of their interactions. Here, we investigated historical demography and genetic exchange between the Carpathian (Lissotriton montandoni, Lm) and smooth (L. vulgaris, Lv) newts. We combine an extensive geographical sampling and multilocus nuclear sequence data with the approximate Bayesian computation framework to test alternative scenarios of divergence and reconstruct the temporal and spatial pattern of gene flow between species. A model of recent (last glacial period) interspecific gene flow was favoured over alternative models. Thus, despite the relatively old divergence (4-6 mya) and presumably long periods of isolation, the species have retained the ability to exchange genes. Nevertheless, the low migration rates (ca. 10(-6) per gene copy per generation) are consistent with strong reproductive isolation between the species. Models allowing demographic changes were favoured, suggesting that the effective population sizes of both species at least doubled as divergence reaching the current ca. 0.2 million in Lm and 1 million in Lv. We found asymmetry in rates of interspecific gene flow between Lm and one evolutionary lineage of Lv. We suggest that intraspecific polymorphism for hybrid incompatibilities segregating within Lv could explain this pattern and propose further tests to distinguish between alternative explanations. Our study highlights the importance of incorporating intraspecific genetic structure into the models investigating the history of divergence. PMID:27288862

  1. Divergence history of the Carpathian and smooth newts modelled in space and time.

    PubMed

    Zieliński, P; Nadachowska-Brzyska, K; Dudek, K; Babik, W

    2016-08-01

    Information about demographic history is essential for the understanding of the processes of divergence and speciation. Patterns of genetic variation within and between closely related species provide insights into the history of their interactions. Here, we investigated historical demography and genetic exchange between the Carpathian (Lissotriton montandoni, Lm) and smooth (L. vulgaris, Lv) newts. We combine an extensive geographical sampling and multilocus nuclear sequence data with the approximate Bayesian computation framework to test alternative scenarios of divergence and reconstruct the temporal and spatial pattern of gene flow between species. A model of recent (last glacial period) interspecific gene flow was favoured over alternative models. Thus, despite the relatively old divergence (4-6 mya) and presumably long periods of isolation, the species have retained the ability to exchange genes. Nevertheless, the low migration rates (ca. 10(-6) per gene copy per generation) are consistent with strong reproductive isolation between the species. Models allowing demographic changes were favoured, suggesting that the effective population sizes of both species at least doubled as divergence reaching the current ca. 0.2 million in Lm and 1 million in Lv. We found asymmetry in rates of interspecific gene flow between Lm and one evolutionary lineage of Lv. We suggest that intraspecific polymorphism for hybrid incompatibilities segregating within Lv could explain this pattern and propose further tests to distinguish between alternative explanations. Our study highlights the importance of incorporating intraspecific genetic structure into the models investigating the history of divergence.

  2. A new design of ion storage accelerator for time-of-flight-MS

    SciTech Connect

    Kraft, A.; Wollnik, H.; Laiko, V.; Dodonov, A.F.

    1995-12-31

    A new Time-of-Flight MS for orthogonal extraction has been constructed. It consists of a API-source, the orthogonal extraction optic and a single stage reflectron as well as a detector with two MCP`s in Chevron-arrangement. The extraction optic has a new design in respect to the prevention of disturbing fields. Such fields take influence on the primary beam during accumulation made and causes noise as well as broadening of mass peaks. This fields arises from the penetration of field through the grid between the two stages of the extraction optic. In this construction, this penetration is compensated by the introduction of an additional electrode which is held at the average virtual potential of the separation grid. By adjusting all electrical parameters of the mass spectrometer (extraction-pulser, backplane of reflector, focussing optics) the peakwidth had been optimized. It has been shown the peakwidth strongly depends on the potential of the compensation electrode. The optimal value corresponds in good agreement with the calculated value (1.7V instead of 1.56V). In the case of Gramicidin S (m=1140) a resolving power of 2000 is achieved.

  3. On the high-resolution mass analysis of the product ions in tandem time-of-flight (TOF/TOF) mass spectrometers using a time-dependent re-acceleration technique.

    PubMed

    Kurnosenko, Sergey; Moskovets, Eugene

    2010-01-01

    The time-dependent reacceleration of product ions produced as a result of dissociation of a single precursor ion in a tandem time-of-flight mass spectrometer is considered for the first time. Analytical expressions for the shapes of electric pulses bringing all the kinetic energies of the product ions to the same value are derived for two cases: forward acceleration mode and deceleration, followed by re-acceleration in the reversed direction (reversed mode). Secondary time-of-flight focusing resulting from the re-acceleration in the reversed mode is shown to be mass-dependent and, when averaged over a wide mass range, the focusing is tight enough to provide mass resolution exceeding 10,000. After time-dependent re-acceleration, additional compression of the ion packet width leading to better mass resolution can be obtained by decelerating the ions in a constant field.

  4. Optimal seismic design of reinforced concrete structures under time-history earthquake loads using an intelligent hybrid algorithm

    NASA Astrophysics Data System (ADS)

    Gharehbaghi, Sadjad; Khatibinia, Mohsen

    2015-03-01

    A reliable seismic-resistant design of structures is achieved in accordance with the seismic design codes by designing structures under seven or more pairs of earthquake records. Based on the recommendations of seismic design codes, the average time-history responses (ATHR) of structure is required. This paper focuses on the optimal seismic design of reinforced concrete (RC) structures against ten earthquake records using a hybrid of particle swarm optimization algorithm and an intelligent regression model (IRM). In order to reduce the computational time of optimization procedure due to the computational efforts of time-history analyses, IRM is proposed to accurately predict ATHR of structures. The proposed IRM consists of the combination of the subtractive algorithm (SA), K-means clustering approach and wavelet weighted least squares support vector machine (WWLS-SVM). To predict ATHR of structures, first, the input-output samples of structures are classified by SA and K-means clustering approach. Then, WWLS-SVM is trained with few samples and high accuracy for each cluster. 9- and 18-storey RC frames are designed optimally to illustrate the effectiveness and practicality of the proposed IRM. The numerical results demonstrate the efficiency and computational advantages of IRM for optimal design of structures subjected to time-history earthquake loads.

  5. Experiment specific processing of residual acceleration data

    NASA Technical Reports Server (NTRS)

    Rogers, Melissa J. B.; Alexander, J. I. D.

    1992-01-01

    To date, most Spacelab residual acceleration data collection projects have resulted in data bases that are overwhelming to the investigator of low-gravity experiments. This paper introduces a simple passive accelerometer system to measure low-frequency accelerations. Model responses for experiments using actual acceleration data are produced and correlations are made between experiment response and the accelerometer time history in order to test the idea that recorded acceleration data and experimental responses can be usefully correlated. Spacelab 3 accelerometer data are used as input to a variety of experiment models, and sensitivity limits are obtained for particular experiment classes. The modeling results are being used to create experiment-specific residual acceleration data processing schemes for interested investigators.

  6. An SDR-Based Real-Time Testbed for GNSS Adaptive Array Anti-Jamming Algorithms Accelerated by GPU.

    PubMed

    Xu, Hailong; Cui, Xiaowei; Lu, Mingquan

    2016-01-01

    Nowadays, software-defined radio (SDR) has become a common approach to evaluate new algorithms. However, in the field of Global Navigation Satellite System (GNSS) adaptive array anti-jamming, previous work has been limited due to the high computational power demanded by adaptive algorithms, and often lack flexibility and configurability. In this paper, the design and implementation of an SDR-based real-time testbed for GNSS adaptive array anti-jamming accelerated by a Graphics Processing Unit (GPU) are documented. This testbed highlights itself as a feature-rich and extendible platform with great flexibility and configurability, as well as high computational performance. Both Space-Time Adaptive Processing (STAP) and Space-Frequency Adaptive Processing (SFAP) are implemented with a wide range of parameters. Raw data from as many as eight antenna elements can be processed in real-time in either an adaptive nulling or beamforming mode. To fully take advantage of the parallelism resource provided by the GPU, a batched method in programming is proposed. Tests and experiments are conducted to evaluate both the computational and anti-jamming performance. This platform can be used for research and prototyping, as well as a real product in certain applications. PMID:26978363

  7. An SDR-Based Real-Time Testbed for GNSS Adaptive Array Anti-Jamming Algorithms Accelerated by GPU.

    PubMed

    Xu, Hailong; Cui, Xiaowei; Lu, Mingquan

    2016-03-11

    Nowadays, software-defined radio (SDR) has become a common approach to evaluate new algorithms. However, in the field of Global Navigation Satellite System (GNSS) adaptive array anti-jamming, previous work has been limited due to the high computational power demanded by adaptive algorithms, and often lack flexibility and configurability. In this paper, the design and implementation of an SDR-based real-time testbed for GNSS adaptive array anti-jamming accelerated by a Graphics Processing Unit (GPU) are documented. This testbed highlights itself as a feature-rich and extendible platform with great flexibility and configurability, as well as high computational performance. Both Space-Time Adaptive Processing (STAP) and Space-Frequency Adaptive Processing (SFAP) are implemented with a wide range of parameters. Raw data from as many as eight antenna elements can be processed in real-time in either an adaptive nulling or beamforming mode. To fully take advantage of the parallelism resource provided by the GPU, a batched method in programming is proposed. Tests and experiments are conducted to evaluate both the computational and anti-jamming performance. This platform can be used for research and prototyping, as well as a real product in certain applications.

  8. An SDR-Based Real-Time Testbed for GNSS Adaptive Array Anti-Jamming Algorithms Accelerated by GPU

    PubMed Central

    Xu, Hailong; Cui, Xiaowei; Lu, Mingquan

    2016-01-01

    Nowadays, software-defined radio (SDR) has become a common approach to evaluate new algorithms. However, in the field of Global Navigation Satellite System (GNSS) adaptive array anti-jamming, previous work has been limited due to the high computational power demanded by adaptive algorithms, and often lack flexibility and configurability. In this paper, the design and implementation of an SDR-based real-time testbed for GNSS adaptive array anti-jamming accelerated by a Graphics Processing Unit (GPU) are documented. This testbed highlights itself as a feature-rich and extendible platform with great flexibility and configurability, as well as high computational performance. Both Space-Time Adaptive Processing (STAP) and Space-Frequency Adaptive Processing (SFAP) are implemented with a wide range of parameters. Raw data from as many as eight antenna elements can be processed in real-time in either an adaptive nulling or beamforming mode. To fully take advantage of the parallelism resource provided by the GPU, a batched method in programming is proposed. Tests and experiments are conducted to evaluate both the computational and anti-jamming performance. This platform can be used for research and prototyping, as well as a real product in certain applications. PMID:26978363

  9. How does leaving home affect marital timing? An event-history analysis of migration and marriage in Nang Rong, Thailand.

    PubMed

    Jampaklay, Aree

    2006-11-01

    This study examines the effects of migration on marital timing in Thailand between 1984 and 2000 using prospective and retrospective survey data from Nang Rong. In contrast to previous results in the literature, event-history analysis of the longitudinal data reveals a positive, not a negative, effect of lagged migration experience on the likelihood of marriage. The findings also indicate gender differences. Migration's positive impact is independent of other life events for women but is completely "explained" by employment for men.

  10. Accelerators (4/5)

    ScienceCinema

    None

    2016-07-12

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  11. Accelerators (3/5)

    ScienceCinema

    None

    2016-07-12

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  12. Accelerators (5/5)

    ScienceCinema

    None

    2016-07-12

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  13. Accelerators (5/5)

    SciTech Connect

    2009-07-09

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  14. Accelerators (4/5)

    SciTech Connect

    2009-07-08

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  15. Accelerators (3/5)

    SciTech Connect

    2009-07-07

    1a) Introduction and motivation 1b) History and accelerator types 2) Transverse beam dynamics 3a) Longitudinal beam dynamics 3b) Figure of merit of a synchrotron/collider 3c) Beam control 4) Main limiting factors 5) Technical challenges Prerequisite knowledge: Previous knowledge of accelerators is not required.

  16. Timing of seasonal migration in mule deer: effects of climate, plant phenology, and life-history characteristics

    USGS Publications Warehouse

    Monteith, Kevin L.; Bleich, Vernon C.; Stephenson, Thomas R.; Pierce, Beck M.; Conner, Mary M.; Klaver, Robert W.; Bowyer, R. Terry

    2011-01-01

    Phenological events of plants and animals are sensitive to climatic processes. Migration is a life-history event exhibited by most large herbivores living in seasonal environments, and is thought to occur in response to dynamics of forage and weather. Decisions regarding when to migrate, however, may be affected by differences in life-history characteristics of individuals. Long-term and intensive study of a population of mule deer (Odocoileus hemionus) in the Sierra Nevada, California, USA, allowed us to document patterns of migration during 11 years that encompassed a wide array of environmental conditions. We used two new techniques to properly account for interval-censored data and disentangle effects of broad-scale climate, local weather patterns, and plant phenology on seasonal patterns of migration, while incorporating effects of individual life-history characteristics. Timing of autumn migration varied substantially among individual deer, but was associated with the severity of winter weather, and in particular, snow depth and cold temperatures. Migratory responses to winter weather, however, were affected by age, nutritional condition, and summer residency of individual females. Old females and those in good nutritional condition risked encountering severe weather by delaying autumn migration, and were thus risk-prone with respect to the potential loss of foraging opportunities in deep snow compared with young females and those in poor nutritional condition. Females that summered on the west side of the crest of the Sierra Nevada delayed autumn migration relative to east-side females, which supports the influence of the local environment on timing of migration. In contrast, timing of spring migration was unrelated to individual life-history characteristics, was nearly twice as synchronous as autumn migration, differed among years, was related to the southern oscillation index, and was influenced by absolute snow depth and advancing phenology of plants

  17. A Brief History in Time of Ion Traps and their Achievements in Science

    DOE R&D Accomplishments Database

    Holzscheiter, M. H.

    1994-01-01

    A short history of the development of the ion storage technique for precision experiments is given. This is by no means meant to be a complete review of the field, but the intend is to use a few specific examples to describe how the persistence, ingenuity, and experimental skill of a few people has generated the core of a field which is now growing at an ever faster pace, spreading into new areas, developing sub fields, and allowing a view at nature, using very modest experimental equipment, which by far rivals even the most ambitious dreams of high energy physics.

  18. A brief history in time of ion traps and their achievements in science

    NASA Astrophysics Data System (ADS)

    Holzscheiter, Michael H.

    1995-01-01

    A short history of the development of the ion storage technique for precision experiments is given. This is by no means meant to be a complete review of the field, but the intend is to use a few specific examples to describe how the persistence, ingenuity, and experimental skill of a few people has generated the core of a field which is now growing at an ever faster pace, spreading into new areas, developing sub fields, and allowing a view at nature, using very modest experimental equipment, which by far rivals even the most ambitious dreams of high energy physics.

  19. A brief history in time of ion traps and their achievements in science

    NASA Astrophysics Data System (ADS)

    Holzscheiter, M. H.

    A short history of the development of the ion storage technique for precision experiments is given. This is by no means meant to be a complete review of the field, but the intend is to use a few specific examples to describe how the persistence, ingenuity, and experimental skill of a few people has generated the core of a field which is now growing at an ever faster pace, spreading into new areas, developing sub fields, and allowing a view at nature, using very modest experimental equipment, which by far rivals even the most ambitious dreams of high energy physics.

  20. Analyzing Morphology and Thermal History of Polybutylene Terephthalate by THz Time-domain Spectroscopy

    NASA Astrophysics Data System (ADS)

    Wietzke, Steffen; Reuter, Marco; Nestle, Nikolaus; Klimov, Evgueni; Zadok, Uri; Fischer, Bernd M.; Koch, Martin

    2011-07-01

    We have measured the frequency-dependent dielectric function of semi-crystalline polybutylene terephthalate (PBT) in the terahertz region between 100 GHz and approximately 2.8 THz. A characteristic band is observed around 2.38 THz. The intensity of this band is a good indicator of the degree of crystallinity of the different samples. A potential assignment of this band is proposed, based on the comparison with spectroscopic data of the structurally very similar polyethylene terephtalate (PET). Furthermore, the frequency-dependent index of refraction of PBT reveals more insight about the morphology and different thermal history of the samples under investigation.

  1. Two-Body Orbit Expansion Due to Time-Dependent Relative Acceleration Rate of the Cosmological Scale Factor

    NASA Astrophysics Data System (ADS)

    Iorio, Lorenzo

    2014-01-01

    By phenomenologically assuming a slow temporal variation of the percent acceleration rate S̈S -1 of the cosmic scale factor S(t), it is shown that the orbit of a local binary undergoes a secular expansion. To first order in the power expansion of S̈S -1 around the present epoch t0, a non-vanishing shift per orbit (Δr) of the two-body relative distance r occurs for eccentric trajectories. A general relativistic expression, which turns out to be cubic in the Hubble parameter H0 at the present epoch, is explicitly calculated for it in the case of matter-dominated epochs with Dark Energy. For a highly eccentric Oort comet orbit with period Pb ≈ 31 Myr, the general relativistic distance shift per orbit turns out to be of the order of (Δr) ≈ 70 km. For the Large Magellanic Cloud, assumed on a bound elliptic orbit around the Milky Way, the shift per orbit is of the order of (Δr) ≈ 2-4 pc. Our result has a general validity since it holds in any cosmological model admitting the Hubble law and a slowly varying S̈S-1(t). More generally, it is valid for an arbitrary Hooke-like extra-acceleration whose "elastic" parameter κ is slowly time-dependent, irrespectively of the physical mechanism which may lead to it. The coefficient κ1 of the first-order term of the power expansion of κ(t) can be preliminarily constrained in a model-independent way down to a κ1 ≤ 2 x 10-13 year-3 level from latest Solar System's planetary observations. The radial velocities of the double lined spectroscopic binary ALPHA Cen AB yield κ1 ≤ 10-8 year-3.

  2. The High Time Resolution Universe Pulsar Survey - XII. Galactic plane acceleration search and the discovery of 60 pulsars

    NASA Astrophysics Data System (ADS)

    Ng, C.; Champion, D. J.; Bailes, M.; Barr, E. D.; Bates, S. D.; Bhat, N. D. R.; Burgay, M.; Burke-Spolaor, S.; Flynn, C. M. L.; Jameson, A.; Johnston, S.; Keith, M. J.; Kramer, M.; Levin, L.; Petroff, E.; Possenti, A.; Stappers, B. W.; van Straten, W.; Tiburzi, C.; Eatough, R. P.; Lyne, A. G.

    2015-07-01

    We present initial results from the low-latitude Galactic plane region of the High Time Resolution Universe pulsar survey conducted at the Parkes 64-m radio telescope. We discuss the computational challenges arising from the processing of the terabyte-sized survey data. Two new radio interference mitigation techniques are introduced, as well as a partially coherent segmented acceleration search algorithm which aims to increase our chances of discovering highly relativistic short-orbit binary systems, covering a parameter space including potential pulsar-black hole binaries. We show that under a constant acceleration approximation, a ratio of data length over orbital period of ≈0.1 results in the highest effectiveness for this search algorithm. From the 50 per cent of data processed thus far, we have redetected 435 previously known pulsars and discovered a further 60 pulsars, two of which are fast-spinning pulsars with periods less than 30 ms. PSR J1101-6424 is a millisecond pulsar whose heavy white dwarf (WD) companion and short spin period of 5.1 ms indicate a rare example of full-recycling via Case A Roche lobe overflow. PSR J1757-27 appears to be an isolated recycled pulsar with a relatively long spin period of 17 ms. In addition, PSR J1244-6359 is a mildly recycled binary system with a heavy WD companion, PSR J1755-25 has a significant orbital eccentricity of 0.09 and PSR J1759-24 is likely to be a long-orbit eclipsing binary with orbital period of the order of tens of years. Comparison of our newly discovered pulsar sample to the known population suggests that they belong to an older population. Furthermore, we demonstrate that our current pulsar detection yield is as expected from population synthesis.

  3. Resolution limitations from detector pulse width and jitter in a linear orthogonal-acceleration time-of-flight mass spectrometer.

    PubMed

    Coles, J N; Guilhaus, M

    1994-08-01

    Recent and ongoing advances in timing electronics together with the development of ionization techniques suited to time-of-flight mass spectrometry (TOF-MS) have contributed to renewed interest in this method of mass analysis. Whereas low resolving powers (m/†m < 500) were once an almost unavoidable drawback in TOF-MS, recent developments in instrument geometries have produced much higher resolving powers for many ion sources. The temporal width of detector pulses and jitter in timing electronics, however, lead to contributions to peak widths that are essentially independent of the mass-analyzer ion optics. The effective detector pulse width (†t d ≈ 1-10 ns typically) can be a limiting factor in the development of high resolution time-of-flight (TOF) instruments with modest drift lengths (∼1 m), It also reduces the mass resolution more seriously for light ions. This article presents a method for distinguishing the instrumental "ion arrival-time" resolution (R o) of a linear TOF mass analyzer from that which is locally measured at a particular mass, limited by the broadening of the detector pulse width and electronics. The method also provides an estimate of †t d, that is useful in determining the temporal performance of the detection system. The model developed here is tested with data from a recently constructed orthogonal-acceleration TOF mass spectrometer equipped with a commercially available transient recorder (a LeCroy 400-Msamplejs digital oscilloscope) from which we obtained R o = 4240 ± 100 [full width at half maximum (FWHM)) and †t d = 3.0 ± 0.1 ns (FWHM).

  4. Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation

    NASA Astrophysics Data System (ADS)

    Mehranian, Abolfazl; Kotasidis, Fotis; Zaidi, Habib

    2016-02-01

    Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results in improved signal-to-noise ratio and convergence rate. In this work, we propose a novel approach to further improve the convergence of the expectation maximization (EM)-based TOF PET image reconstruction algorithm through subsetization of emission data over TOF bins as well as azimuthal bins. Given the prevalence of TOF PET, we elaborated the practical and efficient implementation of TOF PET image reconstruction through the pre-computation of TOF weighting coefficients while exploiting the same in-plane and axial symmetries used in pre-computation of geometric system matrix. In the proposed subsetization approach, TOF PET data were partitioned into a number of interleaved TOF subsets, with the aim of reducing the spatial coupling of TOF bins and therefore to improve the convergence of the standard maximum likelihood expectation maximization (MLEM) and ordered subsets EM (OSEM) algorithms. The comparison of on-the-fly and pre-computed TOF projections showed that the pre-computation of the TOF weighting coefficients can considerably reduce the computation time of TOF PET image reconstruction. The convergence rate and bias-variance performance of the proposed TOF subsetization scheme were evaluated using simulated, experimental phantom and clinical studies. Simulations demonstrated that as the number of TOF subsets is increased, the convergence rate of MLEM and OSEM algorithms is improved. It was also found that for the same computation time, the proposed subsetization gives rise to further convergence. The bias-variance analysis of the experimental NEMA phantom and a clinical

  5. Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation.

    PubMed

    Mehranian, Abolfazl; Kotasidis, Fotis; Zaidi, Habib

    2016-02-01

    Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results in improved signal-to-noise ratio and convergence rate. In this work, we propose a novel approach to further improve the convergence of the expectation maximization (EM)-based TOF PET image reconstruction algorithm through subsetization of emission data over TOF bins as well as azimuthal bins. Given the prevalence of TOF PET, we elaborated the practical and efficient implementation of TOF PET image reconstruction through the pre-computation of TOF weighting coefficients while exploiting the same in-plane and axial symmetries used in pre-computation of geometric system matrix. In the proposed subsetization approach, TOF PET data were partitioned into a number of interleaved TOF subsets, with the aim of reducing the spatial coupling of TOF bins and therefore to improve the convergence of the standard maximum likelihood expectation maximization (MLEM) and ordered subsets EM (OSEM) algorithms. The comparison of on-the-fly and pre-computed TOF projections showed that the pre-computation of the TOF weighting coefficients can considerably reduce the computation time of TOF PET image reconstruction. The convergence rate and bias-variance performance of the proposed TOF subsetization scheme were evaluated using simulated, experimental phantom and clinical studies. Simulations demonstrated that as the number of TOF subsets is increased, the convergence rate of MLEM and OSEM algorithms is improved. It was also found that for the same computation time, the proposed subsetization gives rise to further convergence. The bias-variance analysis of the experimental NEMA phantom and a clinical

  6. Three-dimensional, Time-Resolved, Intrafraction Motion Monitoring Throughout Stereotactic Liver Radiation Therapy on a Conventional Linear Accelerator

    SciTech Connect

    Worm, Esben S.; Høyer, Morten; Fledelius, Walter; Poulsen, Per R.

    2013-05-01

    Purpose: To investigate the time-resolved 3-dimensional (3D) internal motion throughout stereotactic body radiation therapy (SBRT) of tumors in the liver using standard x-ray imagers of a conventional linear accelerator. Methods and Materials: Ten patients with implanted gold markers received 11 treatment courses of 3-fraction SBRT in a stereotactic body-frame on a conventional linear accelerator. Two pretreatment and 1 posttreatment cone-beam computed tomography (CBCT) scans were acquired during each fraction. The CBCT projection images were used to estimate the internal 3D marker motion during CBCT acquisition with 11-Hz resolution by a monoscopic probability-based method. Throughout the treatment delivery by conformal or volumetric modulated arc fields, simultaneous MV portal imaging (8 Hz) and orthogonal kV imaging (5 Hz) were applied to determine the 3D marker motion using either MV/kV triangulation or the monoscopic method when marker segmentation was unachievable in either MV or kV images. The accuracy of monoscopic motion estimation was quantified by also applying monoscopic estimation as a test for all treatments during which MV/kV triangulation was possible. Results: Root-mean-square deviations between monoscopic estimations and triangulations were less than 1.0 mm. The mean 3D intrafraction and intrafield motion ranges during liver SBRT were 17.6 mm (range, 5.6-39.5 mm) and 11.3 mm (2.1-35.5mm), respectively. The risk of large intrafraction baseline shifts correlated with intrafield respiratory motion range. The mean 3D intrafractional marker displacement relative to the first CBCT was 3.4 mm (range, 0.7-14.5 mm). The 3D displacements exceeded 8.8 mm 10% of the time. Conclusions: Highly detailed time-resolved internal 3D motion was determined throughout liver SBRT using standard imaging equipment. Considerable intrafraction motion was observed. The demonstrated methods provide a widely available approach for motion monitoring that, combined with motion

  7. Interactions of Grazing History, Cattle Removal and Time since Rain Drive Divergent Short-Term Responses by Desert Biota

    PubMed Central

    Frank, Anke S. K.; Dickman, Chris R.; Wardle, Glenda M.; Greenville, Aaron C.

    2013-01-01

    Arid grasslands are used worldwide for grazing by domestic livestock, generating debate about how this pastoral enterprise may influence native desert biota. One approach to resolving this question is to experimentally reduce livestock numbers and measure the effects. However, a key challenge in doing this is that historical grazing impacts are likely to be cumulative and may therefore confound comparisons of the short-term responses of desert biota to changes in stocking levels. Arid areas are also subject to infrequent flooding rainfalls that drive productivity and dramatically alter abundances of flora and fauna. We took advantage of an opportunity to study the recent effects of a property-scale cattle removal on two properties with similarly varied grazing histories in central Australia. Following the removal of cattle in 2006 and before and after a significant rainfall event at the beginning of 2007, we sampled vegetation and small vertebrates on eight occasions until October 2008. Our results revealed significant interactions of time of survey with both grazing history and grazing removal for vascular plants, small mammals and reptiles. The mammals exhibited a three-way interaction of time, grazing history and grazing removal, thus highlighting the importance of careful sampling designs and timing for future monitoring. The strongest response to the cessation of grazing after two years was depressed reproductive output of plants in areas where cattle continued to graze. Our results confirm that neither vegetation nor small vertebrates necessarily respond immediately to the removal of livestock, but that rainfall events and cumulative grazing history are key determinants of floral and faunal performance in grassland landscapes with low and variable rainfall. We suggest that improved assessments could be made of the health of arid grazing environments if long-term monitoring were implemented to track the complex interactions that influence how native biota

  8. Time history solution program, L225 (TEV126). Volume 2: Supplemental system design and maintenance document. [for airplane dynamic response using frequency response data

    NASA Technical Reports Server (NTRS)

    Tornallyay, A.; Clemmons, R. E.; Kroll, R. I.

    1979-01-01

    The time history solution program L225 (TEV126) is described. The program calculates the time responses of a linear system by convoluting the impulsive response functions with the time dependent excitation. The convolution is performed as a multiplication in the frequency domain. Fast Fourier transform techniques are used to transform the product back into the time domain to obtain response time histories. The design and structure of the program is presented.

  9. GPU accelerated real-time multi-functional spectral-domain optical coherence tomography system at 1300 nm.

    PubMed

    Wang, Yan; Oh, Christian M; Oliveira, Michael C; Islam, M Shahidul; Ortega, Arthur; Park, B Hyle

    2012-07-01

    We present a GPU accelerated multi-functional spectral domain optical coherence tomography system at 1300 nm. The system is capable of real-time processing and display of every intensity image, comprised of 512 pixels by 2048 A-lines acquired at 20 frames per second. The update rate for all four images with size of 512 pixels by 2048 A-lines simultaneously (intensity, phase retardation, flow and en face view) is approximately 10 frames per second. Additionally, we report for the first time the characterization of phase retardation and diattenuation by a sample comprised of a stacked set of polarizing film and wave plate. The calculated optic axis orientation, phase retardation and diattenuation match well with expected values. The speed of each facet of the multi-functional OCT CPU-GPU hybrid acquisition system, intensity, phase retardation, and flow, were separately demonstrated by imaging a horseshoe crab lateral compound eye, a non-uniformly heated chicken muscle, and a microfluidic device. A mouse brain with thin skull preparation was imaged in vivo and demonstrated the capability of the system for live multi-functional OCT visualization. PMID:22772175

  10. Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance.

    PubMed

    Rao, Lang; Bu, Lin-Lin; Xu, Jun-Hua; Cai, Bo; Yu, Guang-Tao; Yu, Xiaolei; He, Zhaobo; Huang, Qinqin; Li, Andrew; Guo, Shi-Shang; Zhang, Wen-Feng; Liu, Wei; Sun, Zhi-Jun; Wang, Hao; Wang, Tza-Huei; Zhao, Xing-Zhong

    2015-12-01

    For decades, poly(ethylene glycol) (PEG) has been widely incorporated into nanoparticles for evading immune clearance and improving the systematic circulation time. However, recent studies have reported a phenomenon known as "accelerated blood clearance (ABC)" where a second dose of PEGylated nanomaterials is rapidly cleared when given several days after the first dose. Herein, we demonstrate that natural red blood cell (RBC) membrane is a superior alternative to PEG. Biomimetic RBC membrane-coated Fe(3)O(4) nanoparticles (Fe(3)O(4) @RBC NPs) rely on CD47, which is a "don't eat me" marker on the RBC surface, to escape immune clearance through interactions with the signal regulatory protein-alpha (SIRP-α) receptor. Fe(3)O(4) @RBC NPs exhibit extended circulation time and show little change between the first and second doses, with no ABC suffered. In addition, the administration of Fe(3)O(4) @RBC NPs does not elicit immune responses on neither the cellular level (myeloid-derived suppressor cells (MDSCs)) nor the humoral level (immunoglobulin M and G (IgM and IgG)). Finally, the in vivo toxicity of these cell membrane-camouflaged nanoparticles is systematically investigated by blood biochemistry, hematology testing, and histology analysis. These findings are significant advancements toward solving the long-existing clinical challenges of developing biomaterials that are able to resist both immune response and rapid clearance. PMID:26488923

  11. GPU accelerated real-time multi-functional spectral-domain optical coherence tomography system at 1300 nm.

    PubMed

    Wang, Yan; Oh, Christian M; Oliveira, Michael C; Islam, M Shahidul; Ortega, Arthur; Park, B Hyle

    2012-07-01

    We present a GPU accelerated multi-functional spectral domain optical coherence tomography system at 1300 nm. The system is capable of real-time processing and display of every intensity image, comprised of 512 pixels by 2048 A-lines acquired at 20 frames per second. The update rate for all four images with size of 512 pixels by 2048 A-lines simultaneously (intensity, phase retardation, flow and en face view) is approximately 10 frames per second. Additionally, we report for the first time the characterization of phase retardation and diattenuation by a sample comprised of a stacked set of polarizing film and wave plate. The calculated optic axis orientation, phase retardation and diattenuation match well with expected values. The speed of each facet of the multi-functional OCT CPU-GPU hybrid acquisition system, intensity, phase retardation, and flow, were separately demonstrated by imaging a horseshoe crab lateral compound eye, a non-uniformly heated chicken muscle, and a microfluidic device. A mouse brain with thin skull preparation was imaged in vivo and demonstrated the capability of the system for live multi-functional OCT visualization.

  12. X-ray bang-time and fusion reaction history at ~ps resolution using RadOptic detection

    SciTech Connect

    Vernon, S P; Lowry, M E; Baker, K L; Bennett, C V; Celeste, J R; Cerjan, C; Haynes, S; Hernandez, V J; Hsing, W W; London, R A; Moran, B; von Wittenau, A S; Steele, P T; Stewart, R E

    2012-05-01

    We report recent progress in the development of RadOptic detectors, radiation to optical converters, that rely upon x-ray absorption induced modulation of the optical refractive index of a semiconductor sensor medium to amplitude modulate an optical probe beam. The sensor temporal response is determined by the dynamics of the electron-hole pair creation and subsequent relaxation in the sensor medium. Response times of a few ps have been demonstrated in a series of experiments conducted at the LLNL Jupiter Laser Facility. This technology will enable x-ray bang-time and fusion burn-history measurements with {approx} ps resolution.

  13. X-ray bang-time and fusion reaction history at picosecond resolution using RadOptic detection

    SciTech Connect

    Vernon, S. P.; Lowry, M. E.; Baker, K. L.; Bennett, C. V.; Celeste, J. R.; Cerjan, C.; Haynes, S.; Hernandez, V. J.; Hsing, W. W.; LaCaille, G. A.; London, R. A.; Moran, B.; Schach von Wittenau, A.; Steele, P. T.; Stewart, R. E.

    2012-10-15

    We report recent progress in the development of RadOptic detectors, radiation to optical converters, that rely upon x-ray absorption induced modulation of the optical refractive index of a semiconductor sensor medium to amplitude modulate an optical probe beam. The sensor temporal response is determined by the dynamics of the electron-hole pair creation and subsequent relaxation in the sensor medium. Response times of a few ps have been demonstrated in a series of experiments conducted at the LLNL Jupiter Laser Facility (JLF). This technology will enable x-ray bang-time and fusion burn-history measurements with {approx} ps resolution.

  14. Localization, time histories, and energy spectra of a new type of recurrent high-energy transient source

    NASA Technical Reports Server (NTRS)

    Atteia, J.-L.; Boer, M.; Hurley, K.; Niel, M.; Vedrenne, G.; Fenimore, E. E.; Klebesadel, R. W.; Laros, J. G.; Kuznetsov, A. V.; Kouveliotou, C.

    1987-01-01

    The detection of a recurrent high-energy transient source which is neither a classical X-ray nor a gamma-ray burster, but whose properties are intermediate between the two, is reported. The energy spectra of 12 recurrent events are found to be soft, characterized by kT's of 34-56 keV. The time histories are short with rise and fall times as fast as about 10 ms. The source location is a 0.12 sq deg region about 10 deg from the Galactic center.

  15. Structure and composition of the distant lunar exosphere: Constraints from ARTEMIS observations of ion acceleration in time-varying fields

    NASA Astrophysics Data System (ADS)

    Halekas, J. S.; Poppe, A. R.; Farrell, W. M.; McFadden, J. P.

    2016-06-01

    By analyzing the trajectories of ionized constituents of the lunar exosphere in time-varying electromagnetic fields, we can place constraints on the composition, structure, and dynamics of the lunar exosphere. Heavy ions travel slower than light ions in the same fields, so by observing the lag between field rotations and the response of ions from the lunar exosphere, we can place constraints on the composition of the ions. Acceleration, Reconnection, Turbulence, and Electrodynamics of Moon's Interaction with the Sun (ARTEMIS) provides an ideal platform to utilize such an analysis, since its two-probe vantage allows precise timing of the propagation of field discontinuities in the solar wind, and its sensitive plasma instruments can detect the ion response. We demonstrate the utility of this technique by using fully time-dependent charged particle tracing to analyze several minutes of ion observations taken by the two ARTEMIS probes ~3000-5000 km above the dusk terminator on 25 January 2014. The observations from this time period allow us to reach several interesting conclusions. The ion production at altitudes of a few hundred kilometers above the sunlit surface of the Moon has an unexpectedly significant contribution from species with masses of 40 amu or greater. The inferred distribution of the neutral source population has a large scale height, suggesting that micrometeorite impact vaporization and/or sputtering play an important role in the production of neutrals from the surface. Our observations also suggest an asymmetry in ion production, consistent with either a compositional variation in neutral vapor production or a local reduction in solar wind sputtering in magnetic regions of the surface.

  16. The history of time and frequency from antiquity to the present day

    NASA Astrophysics Data System (ADS)

    Levine, Judah

    2016-04-01

    I will discuss the evolution of the definitions of time, time interval, and frequency from antiquity to the present day. The earliest definitions of these parameters were based on a time interval defined by widely observed apparent astronomical phenomena, so that techniques of time distribution were not necessary. With this definition, both time, as measured by clocks, and frequency, as realized by some device, were derived quantities. On the other hand, the fundamental parameter today is a frequency based on the properties of atoms, so that the situation is reversed and time and time interval are now derived quantities. I will discuss the evolution of this transition and its consequences. In addition, the international standards of both time and frequency are currently realized by combining the data from a large number of devices located at many different laboratories, and this combination depends on (and is often limited by) measurements of the times of clocks located at widely-separated laboratories. I will discuss how these measurements are performed and how the techniques have evolved over time.

  17. "Don't Know Much about History": The New York Times 1943 Survey of U.S. History and the Controversy It Generated

    ERIC Educational Resources Information Center

    Halvorsen, Anne-Lise

    2012-01-01

    Background/Context: Educators, parents, politicians, and the media often complain that young people know little history and compare them unfavorably to better-educated, earlier generations. However, the charge is exaggerated. Young people have performed poorly on history tests for decades. Students' poor scores on one test in particular, the focus…

  18. VAiRoma: A Visual Analytics System for Making Sense of Places, Times, and Events in Roman History.

    PubMed

    Cho, Isaac; Dou, Wewnen; Wang, Derek Xiaoyu; Sauda, Eric; Ribarsky, William

    2016-01-01

    Learning and gaining knowledge of Roman history is an area of interest for students and citizens at large. This is an example of a subject with great sweep (with many interrelated sub-topics over, in this case, a 3,000 year history) that is hard to grasp by any individual and, in its full detail, is not available as a coherent story. In this paper, we propose a visual analytics approach to construct a data driven view of Roman history based on a large collection of Wikipedia articles. Extracting and enabling the discovery of useful knowledge on events, places, times, and their connections from large amounts of textual data has always been a challenging task. To this aim, we introduce VAiRoma, a visual analytics system that couples state-of-the-art text analysis methods with an intuitive visual interface to help users make sense of events, places, times, and more importantly, the relationships between them. VAiRoma goes beyond textual content exploration, as it permits users to compare, make connections, and externalize the findings all within the visual interface. As a result, VAiRoma allows users to learn and create new knowledge regarding Roman history in an informed way. We evaluated VAiRoma with 16 participants through a user study, with the task being to learn about roman piazzas through finding relevant articles and new relationships. Our study results showed that the VAiRoma system enables the participants to find more relevant articles and connections compared to Web searches and literature search conducted in a roman library. Subjective feedback on VAiRoma was also very positive. In addition, we ran two case studies that demonstrate how VAiRoma can be used for deeper analysis, permitting the rapid discovery and analysis of a small number of key documents even when the original collection contains hundreds of thousands of documents.

  19. VAiRoma: A Visual Analytics System for Making Sense of Places, Times, and Events in Roman History.

    PubMed

    Cho, Isaac; Dou, Wewnen; Wang, Derek Xiaoyu; Sauda, Eric; Ribarsky, William

    2016-01-01

    Learning and gaining knowledge of Roman history is an area of interest for students and citizens at large. This is an example of a subject with great sweep (with many interrelated sub-topics over, in this case, a 3,000 year history) that is hard to grasp by any individual and, in its full detail, is not available as a coherent story. In this paper, we propose a visual analytics approach to construct a data driven view of Roman history based on a large collection of Wikipedia articles. Extracting and enabling the discovery of useful knowledge on events, places, times, and their connections from large amounts of textual data has always been a challenging task. To this aim, we introduce VAiRoma, a visual analytics system that couples state-of-the-art text analysis methods with an intuitive visual interface to help users make sense of events, places, times, and more importantly, the relationships between them. VAiRoma goes beyond textual content exploration, as it permits users to compare, make connections, and externalize the findings all within the visual interface. As a result, VAiRoma allows users to learn and create new knowledge regarding Roman history in an informed way. We evaluated VAiRoma with 16 participants through a user study, with the task being to learn about roman piazzas through finding relevant articles and new relationships. Our study results showed that the VAiRoma system enables the participants to find more relevant articles and connections compared to Web searches and literature search conducted in a roman library. Subjective feedback on VAiRoma was also very positive. In addition, we ran two case studies that demonstrate how VAiRoma can be used for deeper analysis, permitting the rapid discovery and analysis of a small number of key documents even when the original collection contains hundreds of thousands of documents. PMID:26529701

  20. "Time enough! Or not enough time!" An oral history investigation of some British and Australian community nurses' responses to demands for "efficiency" in health care, 1960-2000.

    PubMed

    Hallett, Christine E; Madsen, Wendy; Pateman, Brian; Bradshaw, Julie

    2012-01-01

    Oral history methodology was used to investigate the perspectives of retired British district nurses and Australian domiciliary nurses who had practiced between 1960 and 2000. Interviews yielded insights into the dramatic changes in community nursing practice during the last four decades of the 20th century. Massive changes in health care and government-led drives for greater efficiency meant moving from practice governed by "experiential time" (in which perception of time depends on the quality of experience) to practice governed by "measured time" (in which experience itself is molded by the measurement of time). Nurses recognized that the quality of their working lives and their relationships with families had been altered by the social, cultural, and political changes, including the drive for professional recognition in nursing itself, soaring economic costs of health care and push for deinstitutionalization of care. Community nurses faced several dilemmas as they grappled with the demands for efficiency created by these changes.

  1. Late time acceleration of the 3-space in a higher dimensional steady state universe in dilaton gravity

    SciTech Connect

    Akarsu, Özgür; Dereli, Tekin E-mail: tdereli@ku.edu.tr

    2013-02-01

    We present cosmological solutions for (1+3+n)-dimensional steady state universe in dilaton gravity with an arbitrary dilaton coupling constant w and exponential dilaton self-interaction potentials in the string frame. We focus particularly on the class in which the 3-space expands with a time varying deceleration parameter. We discuss the number of the internal dimensions and the value of the dilaton coupling constant to determine the cases that are consistent with the observed universe and the primordial nucleosynthesis. The 3-space starts with a decelerated expansion rate and evolves into accelerated expansion phase subject to the values of w and n, but ends with a Big Rip in all cases. We discuss the cosmological evolution in further detail for the cases w = 1 and w = ½ that permit exact solutions. We also comment on how the universe would be conceived by an observer in four dimensions who is unaware of the internal dimensions and thinks that the conventional general relativity is valid at cosmological scales.

  2. Thermal history of the H-chondrite parent body: Implications for metamorphic grade and accretionary time-scales

    NASA Astrophysics Data System (ADS)

    Monnereau, Marc; Toplis, Michael J.; Baratoux, David; Guignard, Jérémy

    2013-10-01

    Multiple temperature-age constraints for eight H-chondrite samples have been used to provide insight into the thermal history of their parent-body through combination with numerical models of thermal evolution assuming internal heating by 26Al and conductive cooling. The effect of spreading accretion out over time is the principal focus of this work. A wide range of body size and date of accretion is systematically tested for different values of accretion rate in order to quantify and illustrate the parameter space that is consistent with the available thermo-chronological data. We conclude that the H-chondrite samples considered have a thermal history consistent with a parent body that at some stage had a concentric 'onion-shell' internal structure. That body had a radius no larger than 130 km, and accretion most probably took place over a time interval on the order of 0.0-0.2 Myr, approximately 2 Myr after CAI condensation. In any case, the time interval of accretion is unlikely to have been more than 0.5 Myr supporting evidence in favour of rapid accretion, possibly through reassembly of the fragments of an earlier generation of bodies. Furthermore, the H-chondrites studied here are inferred to have come from a wide depth range within the body where they experienced metamorphism, indicating that preservation of the onion-shell structure is unlikely. The presence of an insulating regolith does not modify this conclusion, as appropriate thermal histories for the three H6 samples considered cannot be reproduced at depths near the surface. Asteroid 6-Hebe may be the parent body of the H-chondrites, but the high bulk density of the latter is difficult to reconcile with a 'rubble-pile' structure of pure H-chondrite material. Finally, optimized thermal histories are used to constrain the temperatures characterizing boundaries between petrological types (800, 1000, and 1140 K for the H3/4, H4/5, and H5/6 boundaries respectively). In detail, the type 6 samples studied

  3. Detection of large ions in time-of-flight mass spectrometry: effects of ion mass and acceleration voltage on microchannel plate detector response.

    PubMed

    Liu, Ranran; Li, Qiyao; Smith, Lloyd M

    2014-08-01

    In time-of-flight mass spectrometry (TOF-MS), ion detection is typically accomplished by the generation and amplification of secondary electrons produced by ions colliding with a microchannel plate (MCP) detector. Here, the response of an MCP detector as a function of ion mass and acceleration voltage is characterized, for singly charged peptide/protein ions ranging from 1 to 290 kDa in mass, and for acceleration voltages from 5 to 25 kV. A nondestructive inductive charge detector (ICD) employed in parallel with MCP detection provides a reliable reference signal to allow accurate calibration of the MCP response. MCP detection efficiencies were very close to unity for smaller ions at high acceleration voltages (e.g., angiotensin, 1046.5 Da, at 25 kV acceleration voltage), but decreased to ~11% for the largest ions examined (immunoglobulin G (IgG) dimer, 290 kDa) even at the highest acceleration voltage employed (25 kV). The secondary electron yield γ (average number of electrons produced per ion collision) is found to be proportional to mv(3.1) (m: ion mass, v: ion velocity) over the entire mass range examined, and inversely proportional to the square root of m in TOF-MS analysis. The results indicate that although MCP detectors indeed offer superlative performance in the detection of smaller peptide/protein species, their performance does fall off substantially for larger proteins, particularly under conditions of low acceleration voltage.

  4. How much can history constrain adaptive evolution? A real-time evolutionary approach of inversion polymorphisms in Drosophila subobscura.

    PubMed

    Fragata, I; Lopes-Cunha, M; Bárbaro, M; Kellen, B; Lima, M; Santos, M A; Faria, G S; Santos, M; Matos, M; Simões, P

    2014-12-01

    Chromosomal inversions are present in a wide range of animals and plants, having an important role in adaptation and speciation. Although empirical evidence of their adaptive value is abundant, the role of different processes underlying evolution of chromosomal polymorphisms is not fully understood. History and selection are likely to shape inversion polymorphism variation to an extent yet largely unknown. Here, we perform a real-time evolution study addressing the role of historical constraints and selection in the evolution of these polymorphisms. We founded laboratory populations of Drosophila subobscura derived from three locations along the European cline and followed the evolutionary dynamics of inversion polymorphisms throughout the first 40 generations. At the beginning, populations were highly differentiated and remained so throughout generations. We report evidence of positive selection for some inversions, variable between foundations. Signs of negative selection were more frequent, in particular for most cold-climate standard inversions across the three foundations. We found that previously observed convergence at the phenotypic level in these populations was not associated with convergence in inversion frequencies. In conclusion, our study shows that selection has shaped the evolutionary dynamics of inversion frequencies, but doing so within the constraints imposed by previous history. Both history and selection are therefore fundamental to predict the evolutionary potential of different populations to respond to global environmental changes.

  5. Particle acceleration

    NASA Technical Reports Server (NTRS)

    Vlahos, L.; Machado, M. E.; Ramaty, R.; Murphy, R. J.; Alissandrakis, C.; Bai, T.; Batchelor, D.; Benz, A. O.; Chupp, E.; Ellison, D.

    1986-01-01

    Data is compiled from Solar Maximum Mission and Hinothori satellites, particle detectors in several satellites, ground based instruments, and balloon flights in order to answer fundamental questions relating to: (1) the requirements for the coronal magnetic field structure in the vicinity of the energization source; (2) the height (above the photosphere) of the energization source; (3) the time of energization; (4) transistion between coronal heating and flares; (5) evidence for purely thermal, purely nonthermal and hybrid type flares; (6) the time characteristics of the energization source; (7) whether every flare accelerates protons; (8) the location of the interaction site of the ions and relativistic electrons; (9) the energy spectra for ions and relativistic electrons; (10) the relationship between particles at the Sun and interplanetary space; (11) evidence for more than one acceleration mechanism; (12) whether there is single mechanism that will accelerate particles to all energies and also heat the plasma; and (13) how fast the existing mechanisms accelerate electrons up to several MeV and ions to 1 GeV.

  6. Linear Accelerators

    SciTech Connect

    Sidorin, Anatoly

    2010-01-05

    In linear accelerators the particles are accelerated by either electrostatic fields or oscillating Radio Frequency (RF) fields. Accordingly the linear accelerators are divided in three large groups: electrostatic, induction and RF accelerators. Overview of the different types of accelerators is given. Stability of longitudinal and transverse motion in the RF linear accelerators is briefly discussed. The methods of beam focusing in linacs are described.

  7. Particle acceleration on Galactic scales

    NASA Astrophysics Data System (ADS)

    Axford, W. I.

    The history of and current ideas concerning the origin of cosmic rays in the Galaxy and in extragalactic sources are surveyed. The observed properties of Galactic cosmic rays and shock acceleration are discussed. It is argued that shock acceleration in various guises is an essential and conceptually the most economical acceleration mechanism.

  8. A new limit on the time between the nucleosynthesis and the acceleration of cosmic rays in supernova remnants using the Co/Ni ratio

    NASA Technical Reports Server (NTRS)

    Webber, W. R.; Gupta, M.

    1990-01-01

    Using new cross section measurements of Ni into Co, data on the Co/Ni ratio in cosmic rays from the HEAO C spacecraft have been reinterpreted in terms of the time between nucleosynthesis and the acceleration of cosmic rays, delta t. The observed Co/Ni ratio is now consistent with interstellar fragmentation only, leading to a small or zero source abundance. In terms of the decay of e-process nucleosynthesis nuclides into Co after a supernova explosion, this permits an estimate of delta t = 4-30,000 yr for the time between nucleosynthesis and the acceleration of cosmic rays if supernovae are the direct progenitors of cosmic rays. These age limits are used in conjunction with models of the expansion of supernova remnants (SNRs), to estimate that cosmic rays are accelerated when the radius of these remnants is between 0.1 and 25 pc.

  9. Space-time analysis of testicular cancer clusters using residential histories: a case-control study in Denmark.

    PubMed

    Sloan, Chantel D; Nordsborg, Rikke B; Jacquez, Geoffrey M; Raaschou-Nielsen, Ole; Meliker, Jaymie R

    2015-01-01

    Though the etiology is largely unknown, testicular cancer incidence has seen recent significant increases in northern Europe and throughout many Western regions. The most common cancer in males under age 40, age period cohort models have posited exposures in the in utero environment or in early childhood as possible causes of increased risk of testicular cancer. Some of these factors may be tied to geography through being associated with behavioral, cultural, sociodemographic or built environment characteristics. If so, this could result in detectable geographic clusters of cases that could lead to hypotheses regarding environmental targets for intervention. Given a latency period between exposure to an environmental carcinogen and testicular cancer diagnosis, mobility histories are beneficial for spatial cluster analyses. Nearest-neighbor based Q-statistics allow for the incorporation of changes in residency in spatial disease cluster detection. Using these methods, a space-time cluster analysis was conducted on a population-wide case-control population selected from the Danish Cancer Registry with mobility histories since 1971 extracted from the Danish Civil Registration System. Cases (N=3297) were diagnosed between 1991 and 2003, and two sets of controls (N=3297 for each set) matched on sex and date of birth were included in the study. We also examined spatial patterns in maternal residential history for those cases and controls born in 1971 or later (N= 589 case-control pairs). Several small clusters were detected when aligning individuals by year prior to diagnosis, age at diagnosis and calendar year of diagnosis. However, the largest of these clusters contained only 2 statistically significant individuals at their center, and were not replicated in SaTScan spatial-only analyses which are less susceptible to multiple testing bias. We found little evidence of local clusters in residential histories of testicular cancer cases in this Danish population. PMID

  10. Real time and online dynamic speckle assessment of growing bacteria using the method of motion history image

    NASA Astrophysics Data System (ADS)

    Ansari, Mohammad Zaheer; Ramírez-Miquet, Evelio E.; Otero, Isabel; Rodríguez, Dania; Darias, Juan G.

    2016-06-01

    This paper reports the application of the motion history image (MHI) method for biospeckle processing of a bacterial growth. The method avoids the complexity as well as the large computation in sequence-matching-based methods and detects whether the speckle structure has changed or not. Encouraging experimental results on the real-time evolution of the growing bacteria during 12 h demonstrate the effectiveness of the proposed method. The MHI presented an online result without loss of resolution and definition. In turn, the MHI also presented the ability to provide a close answer to the traditional offline method of generalized differences.

  11. Real time and online dynamic speckle assessment of growing bacteria using the method of motion history image

    NASA Astrophysics Data System (ADS)

    Ansari, Mohammad Zaheer; Ramírez-Miquet, Evelio E.; Otero, Isabel; Rodríguez, Dania; Darias, Juan G.

    2016-06-01

    This paper reports the application of the motion history image (MHI) method for biospeckle processing of a bacterial growth. The method avoids the complexity as well as the large computation in sequence-matching-based methods and detects whether the speckle structure has changed or not. Encouraging experimental results on the real-time evolution of the growing bacteria during 12 h demonstrate the effectiveness of the proposed method. The MHI presented an online result without loss of resolution and definition. In turn, the MHI also presented the ability to provide a close answer to the traditional offline method of generalized differences.

  12. Time-History Data of Maneuvers Performed by a Republic F84G Airplane During Squadron Operational Training

    NASA Technical Reports Server (NTRS)

    Hamer, Harold A.; Mayo, Alton P.

    1953-01-01

    Preliminary results of one phase of a control-motion study program involving several jet fighter-type airplanes are presented in time-history form and are summarized as maximum measured quantities plotted against indicated airspeed. The results pertain to approximately 1,000 maneuvers performed by a Republic F-84G jet-fighter airplane during squadron operational training. The data include most tactical maneuvers of which the F-84G airplane is capable. Maneuvers were performed at pressure altitudes of 0 to 30,000 feet with indicated airspeeds ranging from the stalling speed to approximately 515 knots.

  13. Cross-sectional study of Pfizer-sponsored clinical trials: assessment of time to publication and publication history

    PubMed Central

    Fay, Lorna

    2016-01-01

    Objective To estimate the proportion of Pfizer-sponsored clinical trials that completed in 2010 and are published as manuscripts in the peer-reviewed literature, and to assess the manuscript development history. Design Retrospective, cross-sectional analysis. Setting Clinical trials registered in ClinicalTrials.gov that completed in 2010 for approved, Pfizer prescription products in patients or vaccines in healthy participants. Main outcome measures The proportion of studies for which the primary outcome(s) was published and the median time from study completion to publication. The manuscript development history included the number of times a manuscript was submitted before it was accepted for publication. Results Among registered clinical trials for which Pfizer was the sponsor that completed in 2010, 76 met all inclusion criteria. The primary outcome(s) for 65 (85%) studies was published in 71 manuscripts; the median time to publication was 31 months (range 3–63 months). Of the remaining 11 studies, 2 had been submitted to at least one journal, 2 had not yet been submitted and 7 had no plans to publish because the study had terminated early due to recruitment challenges. Manuscripts accepted at the first choice journal were published at median time of 28 months (range 8–63, n=31), those accepted at second choice journal were published at 32 months (3–45, n=19), and for those accepted at third choice journal, it was 40 months (range 24–53, n=13). Conclusions The publication rate and median time to publication from study completion for Pfizer-sponsored studies were comparable to those previously reported for combined analyses of industry and non-industry sectors. Opportunities exist for sponsors, authors and journals to explore ideas that would facilitate more timely publication for clinical trial results. However, to be effective, such changes may need to revisit the entire publication process. PMID:27431904

  14. Teaching Poetry Tips; Teaching English without Desks; A Brief History of Time and the "Red Clock."

    ERIC Educational Resources Information Center

    Reid, Gem; And Others

    1993-01-01

    This issue of "Insights into Open Education" presents three short articles dealing with teaching poetry, English instruction, and the concept of time. The first article, "Teaching Poetry Tips" (Gem Reid), discusses the author's experiences conducting a week-long poetry workshop for a class of 30 second graders. The second article, "Teaching…

  15. Women in History: Mary Parker Follett--A Leadership Theorist Ahead of Her Time

    ERIC Educational Resources Information Center

    Gaspar, Sandy

    2004-01-01

    This article profiles Mary Parker Follet, a management and leadership voice in the 1920s and 30s who was far ahead of her time. Throughout her lifetime, Follet refused to accept the dualities and dichotomies that threatened to divide individuals and organizations. In her book, "The New State," Follet argued that group organization and local…

  16. How Constant Momentum Acceleration Decouples Energy and Space Focusing in Distance-of-Flight and Time-of-Flight Mass Spectrometries

    SciTech Connect

    Dennis, Elise; Gundlach-Graham, Alexander W.; Enke, Chris; Ray, Steven J.; Carado, Anthony J.; Barinaga, Charles J.; Koppenaal, David W.; Hieftje, Gary M.

    2013-05-01

    Time-of-flight (TOF) and distance-of-flight (DOF) mass spectrometers require means for focusing ions at the detector(s) because of initial dispersions of position and energy at the time of their acceleration. Time-of-flight mass spectrometers ordinarily employ constant energy acceleration (CEA), which creates a space-focus plane at which the initial spatial dispersion is corrected. In contrast, constant-momentum acceleration (CMA), in conjunction with an ion mirror, provides focus of the initial energy dispersion at the energy focus time for ions of all m/z at their respective positions along the flight path. With CEA, the initial energy dispersion is not simultaneously correctable as its effect on ion velocity is convoluted with that of the spatial dispersion. The initial spatial dispersion with CMA remains unchanged throughout the field-free region of the flight path, so spatial dispersion can be reduced before acceleration. Improved focus is possible when each dispersion can be addressed independently. With minor modification, a TOF mass spectrometer can be operated in CMA mode by treating the TOF detector as though it were a single element in the array of detectors that would be used in a DOF mass spectrometer. Significant improvement in mass resolution is thereby achieved, albeit over a narrow range of m/z values. In this paper, experimental and theoretical results are presented that illustrate the energy-focusing capabilities of both DOF and TOF mass spectrometry.

  17. The effect of intruded events on peak time: the role of reinforcement history during the intruded event.

    PubMed

    Aum, SangWeon; Brown, Bruce L; Hemmes, Nancy S

    2007-02-22

    Pigeons were studied in an extension of a study by Aum et al. [Aum, S., Brown, B.L., Hemmes, N.S. 2004. The effects of concurrent task and gap events on peak time in the peak procedure. Behav. Process. 65, 43-56] on timing behavior under a discrete-trial fixed-interval (FI) procedure during which 6-s intruded events were superimposed on peak-interval (PI) test trials. In Aum et al., one event consisted in termination of the timing cue (gap trial); the other was a stimulus in the presence of which subjects had been trained to respond under an independent random-interval (RI) schedule of reinforcement (concurrent task trial). Aum et al. found a disruption of timing on concurrent task trials that was greater than that on gap trials. The present study investigated history of reinforcement associated with intruded events as a possible explanation of this earlier finding. After training to peck a side key on a 30-s PI procedure, discrimination training was conducted on the center key in separate sessions; red or green 6-s stimuli were associated with RI 24s or EXT (extinction) schedules. During testing under the PI procedure, three types of intruded events were presented during probe trials--the stimulus associated with the RI (S+) or EXT (S-) schedule during discrimination training, or a gap (termination of the side-keylight). Intruded events occurred 3, 9, or 15s after PI trial onset. Effects of reinforcement history were revealed as substantial disruption of timing during the S+ event and relatively little disruption during the S- event. Intermediate effects were found for the gap event. Results indicate that postcue effects are at least partially responsible for the disruptive effects of the S+ event. PMID:17157998

  18. A new time tree reveals Earth history's imprint on the evolution of modern birds.

    PubMed

    Claramunt, Santiago; Cracraft, Joel

    2015-12-01

    Determining the timing of diversification of modern birds has been difficult. We combined DNA sequences of clock-like genes for most avian families with 130 fossil birds to generate a new time tree for Neornithes and investigated their biogeographic and diversification dynamics. We found that the most recent common ancestor of modern birds inhabited South America around 95 million years ago, but it was not until the Cretaceous-Paleogene transition (66 million years ago) that Neornithes began to diversify rapidly around the world. Birds used two main dispersion routes: reaching the Old World through North America, and reaching Australia and Zealandia through Antarctica. Net diversification rates increased during periods of global cooling, suggesting that fragmentation of tropical biomes stimulated speciation. Thus, we found pervasive evidence that avian evolution has been influenced by plate tectonics and environmental change, two basic features of Earth's dynamics.

  19. A new time tree reveals Earth history's imprint on the evolution of modern birds.

    PubMed

    Claramunt, Santiago; Cracraft, Joel

    2015-12-01

    Determining the timing of diversification of modern birds has been difficult. We combined DNA sequences of clock-like genes for most avian families with 130 fossil birds to generate a new time tree for Neornithes and investigated their biogeographic and diversification dynamics. We found that the most recent common ancestor of modern birds inhabited South America around 95 million years ago, but it was not until the Cretaceous-Paleogene transition (66 million years ago) that Neornithes began to diversify rapidly around the world. Birds used two main dispersion routes: reaching the Old World through North America, and reaching Australia and Zealandia through Antarctica. Net diversification rates increased during periods of global cooling, suggesting that fragmentation of tropical biomes stimulated speciation. Thus, we found pervasive evidence that avian evolution has been influenced by plate tectonics and environmental change, two basic features of Earth's dynamics. PMID:26824065

  20. Analyzing Factors Affecting Emergency Department Length of Stay-Using a Competing Risk-accelerated Failure Time Model.

    PubMed

    Chaou, Chung-Hsien; Chiu, Te-Fa; Yen, Amy Ming-Fang; Ng, Chip-Jin; Chen, Hsiu-Hsi

    2016-04-01

    Emergency department (ED) length of stay (LOS) is associated with ED crowding and related complications. Previous studies either analyzed single patient disposition groups or combined different endpoints as a whole. The aim of this study is to evaluate different effects of relevant factors affecting ED LOS among different patient disposition groups.This is a retrospective electronic data analysis. The ED LOS and relevant covariates of all patients between January 2013 and December 2013 were collected. A competing risk accelerated failure time model was used to compute endpoint type-specific time ratios (TRs) for ED LOS.A total of 149,472 patients was included for analysis with an overall medium ED LOS of 2.15 [interquartile range (IQR) = 6.51] hours. The medium LOS for discharged, admission, and mortality patients was 1.46 (IQR = 2.07), 11.3 (IQR = 33.2), and 7.53 (IQR = 28.0) hours, respectively. In multivariate analysis, age (TR = 1.012, P < 0.0001], higher acuity (triage level I vs level V, TR = 2.371, P < 0.0001), pediatric nontrauma (compared with adult nontrauma, TR = 3.084, P < 0.0001), transferred patients (TR = 2.712, P < 0.0001), and day shift arrival (compared with night shift, TR = 1.451, P < 0.0001) were associated with prolonged ED LOS in the discharged patient group. However, opposite results were noted for higher acuity (triage level I vs level V, TR = 0.532, P < 0.0001), pediatric nontrauma (TR = 0.375, P < 0.0001), transferred patients (TR = 0.852, P < 0.0001), and day shift arrival (TR = 0.88, P < 0.0001) in the admission patient group.Common influential factors such as age, patient entity, triage acuity level, or arrival time may have varying effects on different disposition groups of patients. These findings and the suggested model could be used for EDs to develop individually tailored approaches to minimize ED LOS and further improve ED crowding status

  1. Analyzing Factors Affecting Emergency Department Length of Stay—Using a Competing Risk-accelerated Failure Time Model

    PubMed Central

    Chaou, Chung-Hsien; Chiu, Te-Fa; Yen, Amy Ming-Fang; Ng, Chip-Jin; Chen, Hsiu-Hsi

    2016-01-01

    Abstract Emergency department (ED) length of stay (LOS) is associated with ED crowding and related complications. Previous studies either analyzed single patient disposition groups or combined different endpoints as a whole. The aim of this study is to evaluate different effects of relevant factors affecting ED LOS among different patient disposition groups. This is a retrospective electronic data analysis. The ED LOS and relevant covariates of all patients between January 2013 and December 2013 were collected. A competing risk accelerated failure time model was used to compute endpoint type-specific time ratios (TRs) for ED LOS. A total of 149,472 patients was included for analysis with an overall medium ED LOS of 2.15 [interquartile range (IQR) = 6.51] hours. The medium LOS for discharged, admission, and mortality patients was 1.46 (IQR = 2.07), 11.3 (IQR = 33.2), and 7.53 (IQR = 28.0) hours, respectively. In multivariate analysis, age (TR = 1.012, P < 0.0001], higher acuity (triage level I vs level V, TR = 2.371, P < 0.0001), pediatric nontrauma (compared with adult nontrauma, TR = 3.084, P < 0.0001), transferred patients (TR = 2.712, P < 0.0001), and day shift arrival (compared with night shift, TR = 1.451, P < 0.0001) were associated with prolonged ED LOS in the discharged patient group. However, opposite results were noted for higher acuity (triage level I vs level V, TR = 0.532, P < 0.0001), pediatric nontrauma (TR = 0.375, P < 0.0001), transferred patients (TR = 0.852, P < 0.0001), and day shift arrival (TR = 0.88, P < 0.0001) in the admission patient group. Common influential factors such as age, patient entity, triage acuity level, or arrival time may have varying effects on different disposition groups of patients. These findings and the suggested model could be used for EDs to develop individually tailored approaches to minimize ED LOS and further improve ED crowding

  2. Gamma-ray burst spectra and time histories from 2 to 400keV

    NASA Astrophysics Data System (ADS)

    Fenimore, E. E.

    1999-01-01

    The Gamma-Ray burst detector on Ginga consisted of a proportional counter to observe the x-rays and a scintillation counter to observe the gamma-rays. It was ideally suited to study the x-rays associated with gamma-ray bursts (GRBs). Ginga detected ~120 GRBs and 22 of them had sufficient statistics to determine spectra from 2 to 400keV. Although the Ginga and BATSE trigger criteria were very similar, the distribution of spectral parameters was different. Ginga observed bend energies in the spectra down to 2keV and had a larger fraction of bursts with low energy power law indexes greater than zero. The average ratio of energy in the x-ray band (2 to 10keV) compared to the gamma-ray band (50 to 300keV) was 24%. Some events had more energy in the x-ray band than in the gamma-ray band. One Ginga event had a period of time preceding the gamma rays that was effectively pure x-ray emission. This x-ray ``preactivity'' might be due to the penchant for the GRB time structure to be broader at lower energy rather than a different physical process. The x-rays tend to rise and fall slower than the gamma rays but they both tend to peak at about the same time. This argues against models involving the injection of relativistic electrons that cool by synchrotron radiation.

  3. Performance optimisation of a new-generation orthogonal-acceleration quadrupole-time-of-flight mass spectrometer.

    PubMed

    Bristow, Tony; Constantine, Jill; Harrison, Mark; Cavoit, Fabien

    2008-04-01

    Orthogonal-acceleration quadrupole time-of-flight (oa-QTOF) mass spectrometers, employed for accurate mass measurement, have been commercially available for well over a decade. A limitation of the early instruments of this type was the narrow ion abundance range over which accurate mass measurements could be made with a high degree of certainty. Recently, a new generation of oa-QTOF mass spectrometers has been developed and these allow accurate mass measurements to be recorded over a much greater range of ion abundances. This development has resulted from new ion detection technology and improved electronic stability or by accurate control of the number of ions reaching the detector. In this report we describe the results from experiments performed to evaluate the mass measurement performance of the Bruker micrOTOF-Q, a member of the new-generation oa-QTOFs. The relationship between mass accuracy and ion abundance has been extensively evaluated and mass measurement accuracy remained stable (+/-1.5 m m/z units) over approximately 3-4 orders of magnitude of ion abundance. The second feature of the Bruker micrOTOF-Q that was evaluated was the SigmaFit function of the software. This isotope pattern-matching algorithm provides an exact numerical comparison of the theoretical and measured isotope patterns as an additional identification tool to accurate mass measurement. The smaller the value, the closer the match between theoretical and measured isotope patterns. This information is then employed to reduce the number of potential elemental formulae produced from the mass measurements. A relationship between the SigmaFit value and ion abundance has been established. The results from the study for both mass accuracy and SigmaFit were employed to define the performance criteria for the micrOTOF-Q. This provided increased confidence in the selection of elemental formulae resulting from accurate mass measurements.

  4. Potential of gas chromatography-orthogonal acceleration time-of-flight mass spectrometry (GC-oaTOFMS) in flavor research.

    PubMed

    Fay, Laurent B; Newton, Anthony; Simian, Hervé; Robert, Fabien; Douce, David; Hancock, Peter; Green, Martin; Blank, Imre

    2003-04-23

    Gas chromatography-orthogonal acceleration time-of-flight mass spectrometry (GC-oaTOFMS) is an emerging technique offering a straightforward access to a resolving power up to 7000. This paper deals with the use of GC-oaTOFMS to identify the flavor components of a complex seafood flavor extract and to quantify furanones formed in model Maillard reactions. A seafood extract was selected as a representative example for complex food flavors and was previously analyzed using GC-quadrupole MS, leaving several molecules unidentified. GC-oaTOFMS analysis was focused on these unknowns to evaluate its potential in flavor research, particularly for determining exact masses. N-Methyldithiodimethylamine, 6-methyl-5-hepten-2-one, and tetrahydro-2,4-dimethyl-4H-pyrrolo[2,1-d]-1,3,5-dithiazine were successfully identified on the basis of the precise mass determination of their molecular ions and their major fragments. A second set of experiments was performed to test the capabilities of the GC-oaTOFMS for quantification. Calibration curves were found to be linear over a dynamic range of 10(3) for the quantification of furanones. The quantitative data obtained using GC-oaTOFMS confirmed earlier results that the formation of 4-hydroxy-2,5-dimethyl-3(2H)-furanone was favored in the xylose/glycine model reaction and 2(or 5)-ethyl-4-hydroxy-5(or 2)-methyl-3(2H)-furanone in the xylose/alanine model reaction. It was concluded that GC-oaTOFMS may become a powerful analytical tool for the flavor chemist for both identification and quantification purposes, the latter in particular when combined with stable isotope dilution assay.

  5. Moving Forward, Looking Back--Historical Perspective, "Big History" and the Return of the "Longue Durée": Time to Develop Our Scale Hopping Muscles

    ERIC Educational Resources Information Center

    Hawkey, Kate

    2015-01-01

    "Big history" is a term receiving a great deal of attention at present, particularly in North America where considerable sums of money have been invested in designing curricula and assessment tools to help teachers teach history at far larger scales of time than normal. Hawkey considers the pros and cons of incorporating components of…

  6. Life history QTLs and natural selection on flowering time in Boechera stricta, a perennial relative of Arabidopsis

    PubMed Central

    Anderson, Jill T.; Lee, Cheng-Ruei; Mitchell-Olds, Thomas

    2011-01-01

    Plants must precisely time flowering to capitalize on favorable conditions. Although we know a great deal about the genetic basis of flowering phenology in model species under controlled conditions, the genetic architecture of this ecologically-important trait is poorly understood in non-model organisms. Here, we evaluated the transition from vegetative growth to flowering in Boechera stricta, a perennial relative of Arabidopsis thaliana. We examined flowering time QTLs using 7,920 recombinant inbred individuals, across seven lab and field environments differing in vernalization, temperature, and photoperiod. Genetic and environmental factors strongly influenced the transition to reproduction. We found directional selection for earlier flowering in the field. In the growth chamber experiment, longer winters accelerated flowering, whereas elevated ambient temperatures delayed flowering. Our analyses identified one large effect QTL (nFT), which influenced flowering time in both experiments and the probability of flowering in the field. In Montana, homozygotes for the native allele at nFT showed a selective advantage of 6.6%. Nevertheless, we found relatively low correlations between flowering times in the field and the growth chambers. Additionally, we detected flowering-related QTLs in the field which were absent across the full range of laboratory conditions, thus emphasizing the need to conduct experiments in natural environments. PMID:21083662

  7. A Time-Calibrated Road Map of Brassicaceae Species Radiation and Evolutionary History[OPEN

    PubMed Central

    Hohmann, Nora; Wolf, Eva M.

    2015-01-01

    The Brassicaceae include several major crop plants and numerous important model species in comparative evolutionary research such as Arabidopsis, Brassica, Boechera, Thellungiella, and Arabis species. As any evolutionary hypothesis needs to be placed in a temporal context, reliably dated major splits within the evolution of Brassicaceae are essential. We present a comprehensive time-calibrated framework with important divergence time estimates based on whole-chloroplast sequence data for 29 Brassicaceae species. Diversification of the Brassicaceae crown group started at the Eocene-to-Oligocene transition. Subsequent major evolutionary splits are dated to ∼20 million years ago, coinciding with the Oligocene-to-Miocene transition, with increasing drought and aridity and transient glaciation events. The age of the Arabidopsis thaliana crown group is 6 million years ago, at the Miocene and Pliocene border. The overall species richness of the family is well explained by high levels of neopolyploidy (43% in total), but this trend is neither directly associated with an increase in genome size nor is there a general lineage-specific constraint. Our results highlight polyploidization as an important source for generating new evolutionary lineages adapted to changing environments. We conclude that species radiation, paralleled by high levels of neopolyploidization, follows genome size decrease, stabilization, and genetic diploidization. PMID:26410304

  8. Timing of chaotic terrain formation in Argadnel Regio, Europa, and implications for geological history

    NASA Astrophysics Data System (ADS)

    Parro, Laura M.; Ruiz, Javier; Pappalardo, Robert T.

    2016-10-01

    Chaos terrains are among the most prominent landforms of Europa, and are generally among the youngest features recorded on the surface. Chaos units were formed by to endogenic activity, maybe related to solid-state convection and thermal diapirism in the ice shell, perhaps aided by melting of salt-rich ice bodies below the surface. In this work, we analyze the different units of chaotic terrain in a portion of Argadnel Regio, a region located on the anti-Jovian hemisphere of Europa, and their possible timing in the general stratigraphic framework of this satellite. Two different chaos units can be differentiated, based on surface texture, morphology, and cross-cutting relationships with other units, and from interpretations based on pre-existing surface restoration through elimination of a low albedo band. The existence of two stratigraphically different chaos units implies that conditions for chaos formation occurred during more than a single discreet time on Europa, at least in Argadnel Regio, and perhaps in other places. The existence of older chaos units on Europa might be related to convective episodes possibly favored by local conditions in the icy shell, such as variations in grain size, abundance of non-water ice-components, or regional thickness of the brittle lithosphere or the entire ice shell.

  9. A Time-Calibrated Road Map of Brassicaceae Species Radiation and Evolutionary History.

    PubMed

    Hohmann, Nora; Wolf, Eva M; Lysak, Martin A; Koch, Marcus A

    2015-10-01

    The Brassicaceae include several major crop plants and numerous important model species in comparative evolutionary research such as Arabidopsis, Brassica, Boechera, Thellungiella, and Arabis species. As any evolutionary hypothesis needs to be placed in a temporal context, reliably dated major splits within the evolution of Brassicaceae are essential. We present a comprehensive time-calibrated framework with important divergence time estimates based on whole-chloroplast sequence data for 29 Brassicaceae species. Diversification of the Brassicaceae crown group started at the Eocene-to-Oligocene transition. Subsequent major evolutionary splits are dated to ∼20 million years ago, coinciding with the Oligocene-to-Miocene transition, with increasing drought and aridity and transient glaciation events. The age of the Arabidopsis thaliana crown group is 6 million years ago, at the Miocene and Pliocene border. The overall species richness of the family is well explained by high levels of neopolyploidy (43% in total), but this trend is neither directly associated with an increase in genome size nor is there a general lineage-specific constraint. Our results highlight polyploidization as an important source for generating new evolutionary lineages adapted to changing environments. We conclude that species radiation, paralleled by high levels of neopolyploidization, follows genome size decrease, stabilization, and genetic diploidization. PMID:26410304

  10. History effects in visual search for monsters: search times, choice biases, and liking.

    PubMed

    Chetverikov, Andrey; Kristjansson, Árni

    2015-02-01

    Repeating targets and distractors on consecutive visual search trials facilitates search performance, whereas switching targets and distractors harms search. In addition, search repetition leads to biases in free choice tasks, in that previously attended targets are more likely to be chosen than distractors. Another line of research has shown that attended items receive high liking ratings, whereas ignored distractors are rated negatively. Potential relations between the three effects are unclear, however. Here we simultaneously measured repetition benefits and switching costs for search times, choice biases, and liking ratings in color singleton visual search for "monster" shapes. We showed that if expectations from search repetition are violated, targets are liked to be less attended than otherwise. Choice biases were, on the other hand, affected by distractor repetition, but not by target/distractor switches. Target repetition speeded search times but had little influence on choice or liking. Our findings suggest that choice biases reflect distractor inhibition, and liking reflects the conflict associated with attending to previously inhibited stimuli, while speeded search follows both target and distractor repetition. Our results support the newly proposed affective-feedback-of-hypothesis-testing account of cognition, and additionally, shed new light on the priming of visual search.

  11. Human history and deep time in nineteenth-century British sciences: An introduction.

    PubMed

    Sera-Shriar, Efram

    2015-06-01

    The historicisation of humans was a major endeavour in nineteenth-century Britain, and one that led to wide-ranging debates involving a variety of disciplinary approaches, new and old. Within the context of science and medicine these discussions centred on the issues of human origins and evolution. Did the various races living throughout the world develop from a single location, or were their physical and social differences evidence for their separate genesis? Which disciplinary tradition offered the best method for tracing human development? Was it even possible to trace that development, or had too much time passed since the dawn of humans? Furthermore, who had the authority to speak about these matters? This special issue will examine these core questions and introduce some of the ways that researchers attempted to historicise humans within the context of nineteenth-century British sciences.

  12. [Purkynje fibers of the heart conduction system--history and the present time].

    PubMed

    Eliska, O

    2006-01-01

    It has been 160 years now since Purkynje published the finding of conduction fibers in the heart in Archiv f. Anatomie u. Physiologie and it has been 166 years since his publication in polish version. Already during Purkynje's life, some anatomists had solved the morphology of these fibers but nobody at that time knew of what great physiological and medical importance this discovery would be for medicine. It was seen as late as in the 20th century and in contemporary times. Purkynje's work indicated the cascade of these discoveries, which were leading in the beginning of the previous century to the formulation of the basic scheme of the conduction system. Purkynje fibers or Purkynje cardiomyocytes are part of the whole complex of the cardiac conduction system which today is classified as specific heart muscle tissue, being responsible for the generation of the heart impulses. From the point of view of ultrastructural composition, the cells of different parts of the cardiac conduction system are partly similar. In contrast to the heart contractile cardiomyocytes, the cells of the cardiac conduction system including Purkynje fibers have a small amount of myofibrils,small mitochondrias, light cytoplasm and a higher glycogen content, but no T-tubular system. They can be detected with some morphological methods. Nevertheless the cells of the conduction system are not completely uniform. They differ in size, number of nexuses-gaps and intercalar discs in individual parts of the conduction system. Nevertheless, these specialized cells work as a whole-unit. Nowadays, the morphology research of all the parts of cardiac conduction system, including Purkynje fibers, is focused on ultrastructural, histochemical and genetical problems. The question is, wheather with future gene/cell therapy disturbances of the conduction system such as arrythmias, can be prevented and cured by replacing the electrical pacemakers with biological ones. If Jan Evangelista Purkynje lived today, he

  13. Can Accelerators Accelerate Learning?

    NASA Astrophysics Data System (ADS)

    Santos, A. C. F.; Fonseca, P.; Coelho, L. F. S.

    2009-03-01

    The 'Young Talented' education program developed by the Brazilian State Funding Agency (FAPERJ) [1] makes it possible for high-schools students from public high schools to perform activities in scientific laboratories. In the Atomic and Molecular Physics Laboratory at Federal University of Rio de Janeiro (UFRJ), the students are confronted with modern research tools like the 1.7 MV ion accelerator. Being a user-friendly machine, the accelerator is easily manageable by the students, who can perform simple hands-on activities, stimulating interest in physics, and getting the students close to modern laboratory techniques.

  14. Can Accelerators Accelerate Learning?

    SciTech Connect

    Santos, A. C. F.; Fonseca, P.; Coelho, L. F. S.

    2009-03-10

    The 'Young Talented' education program developed by the Brazilian State Funding Agency (FAPERJ)[1] makes it possible for high-schools students from public high schools to perform activities in scientific laboratories. In the Atomic and Molecular Physics Laboratory at Federal University of Rio de Janeiro (UFRJ), the students are confronted with modern research tools like the 1.7 MV ion accelerator. Being a user-friendly machine, the accelerator is easily manageable by the students, who can perform simple hands-on activities, stimulating interest in physics, and getting the students close to modern laboratory techniques.

  15. Pubertal timing and sexual risk behaviors among rural African American male youth: testing a model based on life history theory.

    PubMed

    Kogan, Steven M; Cho, Junhan; Simons, Leslie Gordon; Allen, Kimberly A; Beach, Steven R H; Simons, Ronald L; Gibbons, Frederick X

    2015-04-01

    Life History Theory (LHT), a branch of evolutionary biology, describes how organisms maximize their reproductive success in response to environmental conditions. This theory suggests that challenging environmental conditions will lead to early pubertal maturation, which in turn predicts heightened risky sexual behavior. Although largely confirmed among female adolescents, results with male youth are inconsistent. We tested a set of predictions based on LHT with a sample of 375 African American male youth assessed three times from age 11 to age 16. Harsh, unpredictable community environments and harsh, inconsistent, or unregulated parenting at age 11 were hypothesized to predict pubertal maturation at age 13; pubertal maturation was hypothesized to forecast risky sexual behavior, including early onset of intercourse, substance use during sexual activity, and lifetime numbers of sexual partners. Results were consistent with our hypotheses. Among African American male youth, community environments were a modest but significant predictor of pubertal timing. Among those youth with high negative emotionality, both parenting and community factors predicted pubertal timing. Pubertal timing at age 13 forecast risky sexual behavior at age 16. Results of analyses conducted to determine whether environmental effects on sexual risk behavior were mediated by pubertal timing were not significant. This suggests that, although evolutionary mechanisms may affect pubertal development via contextual influences for sensitive youth, the factors that predict sexual risk behavior depend less on pubertal maturation than LHT suggests. PMID:25501863

  16. [Purkynje fibers of the heart conduction system--history and the present time].

    PubMed

    Eliska, O

    2006-01-01

    It has been 160 years now since Purkynje published the finding of conduction fibers in the heart in Archiv f. Anatomie u. Physiologie and it has been 166 years since his publication in polish version. Already during Purkynje's life, some anatomists had solved the morphology of these fibers but nobody at that time knew of what great physiological and medical importance this discovery would be for medicine. It was seen as late as in the 20th century and in contemporary times. Purkynje's work indicated the cascade of these discoveries, which were leading in the beginning of the previous century to the formulation of the basic scheme of the conduction system. Purkynje fibers or Purkynje cardiomyocytes are part of the whole complex of the cardiac conduction system which today is classified as specific heart muscle tissue, being responsible for the generation of the heart impulses. From the point of view of ultrastructural composition, the cells of different parts of the cardiac conduction system are partly similar. In contrast to the heart contractile cardiomyocytes, the cells of the cardiac conduction system including Purkynje fibers have a small amount of myofibrils,small mitochondrias, light cytoplasm and a higher glycogen content, but no T-tubular system. They can be detected with some morphological methods. Nevertheless the cells of the conduction system are not completely uniform. They differ in size, number of nexuses-gaps and intercalar discs in individual parts of the conduction system. Nevertheless, these specialized cells work as a whole-unit. Nowadays, the morphology research of all the parts of cardiac conduction system, including Purkynje fibers, is focused on ultrastructural, histochemical and genetical problems. The question is, wheather with future gene/cell therapy disturbances of the conduction system such as arrythmias, can be prevented and cured by replacing the electrical pacemakers with biological ones. If Jan Evangelista Purkynje lived today, he

  17. Timing of Ossification in Duck, Quail, and Zebra Finch: Intraspecific Variation, Heterochronies, and Life History Evolution

    PubMed Central

    Mitgutsch, Christian; Wimmer, Corinne; Sánchez-Villagra, Marcelo R.; Hahnloser, Richard; Schneider, Richard A.

    2011-01-01

    Skeletogenic heterochronies have gained much attention in comparative developmental biology. The temporal appearance of mineralized individual bones in a species – the species ossification sequence – is an excellent marker in this kind of study. Several publications describe interspecific variation, but only very few detail intraspecific variation. In this study, we describe and analyze the temporal order of ossification of skeletal elements in the zebra finch, Taeniopygia guttata, the Japanese quail, Coturnix coturnix japonica, and the White Pekin duck, a domestic race of the mallard Anas platyrhynchos, and explore patterns of intraspecific variation in these events. The overall sequences were found to be conserved. In the duck, variability is present in the relative timing of ossification in the occipital, the basisphenoid and the otic regions of the skull and the phalanges in the postcranium. This variation appears generally in close temporal proximity. Comparison with previously published data shows differences in ossification sequence in the skull, the feet, and the pelvis in the duck, and especially the pelvis in the quail. This clearly documents variability among different breeds. PMID:21728797

  18. Acceleration and Velocity Sensing from Measured Strain

    NASA Technical Reports Server (NTRS)

    Pak, Chan-Gi; Truax, Roger

    2016-01-01

    A simple approach for computing acceleration and velocity of a structure from the strain is proposed in this study. First, deflection and slope of the structure are computed from the strain using a two-step theory. Frequencies of the structure are computed from the time histories of strain using a parameter estimation technique together with an Autoregressive Moving Average model. From deflection, slope, and frequencies of the structure, acceleration and velocity of the structure can be obtained using the proposed approach. shape sensing, fiber optic strain sensor, system equivalent reduction and expansion process.

  19. Are Transition Periods the Optimal Time for Acceleration? The Training of a First Order Conservation in Young Children.

    ERIC Educational Resources Information Center

    Biskin, Donald S.; Rice, Deborah

    The effectiveness of acceleration training with children who were in a transition period was examined. Forty-eight kindergarten children were separated into four groups on the basis of their status (Preoperational vs. Transitional) and whether or not they received three sessions of inversion-negation training. The results of the immediate and…

  20. Statistical properties of the time histories of cosmic gamma-ray bursts detected by the BATSE experiment of the Compton gamma-ray observatory

    NASA Technical Reports Server (NTRS)

    Sagdeev, Roald

    1995-01-01

    The main scientific objectives of the project were: (1) Calculation of average time history for different subsets of BATSE gamma-ray bursts; (2) Comparison of averaged parameters and averaged time history for different Burst And Transient Source Experiments (BASTE) Gamma Ray Bursts (GRB's) sets; (3) Comparison of results obtained with BATSE data with those obtained with APEX experiment at PHOBOS mission; and (4) Use the results of (1)-(3) to compare current models of gamma-ray bursts sources.

  1. Effect of cross exercise on quadriceps acceleration reaction time and subjective scores (Lysholm questionnaire) following anterior cruciate ligament reconstruction

    PubMed Central

    Papandreou, Maria G; Billis, Evdokia V; Antonogiannakis, Emmanouel M; Papaioannou, Nikos A

    2009-01-01

    Background Anterior cruciate ligament (ACL) injury or reconstruction can cause knee impairments and disability. Knee impairments are related to quadriceps performance – accelerated reaction time (ART) – and disability to performance of daily living activities which is assessed by questionnaires such as the Lysholm knee score. The purposes of this study were to investigate the effect of cross exercise, as supplementary rehabilitation to the early phase of ACL reconstruction: a) on quadriceps ART at the angles 45°, 60° and 90° of knee flexion and, b) on the subjective scores of disability in ACL reconstructed patients. Methods 42 patients who underwent ACL reconstruction were randomly divided into 3 groups, two experimental and one control. All groups followed the same rehabilitation program. The experimental groups followed 8 weeks of cross eccentric exercise (CEE) on the uninjured knee; 3 d/w, and 5 d/w respectively. Quadriceps ART was measured at 45°, 60° and 90° of knee flexion pre and nine weeks post-operatively using an isokinetic dynamometer. Patients also completed pre and post operatively the Lysholm questionnaire whereby subjective scores were recorded. Results Two factor ANOVA showed significant differences in ART at 90° among the groups (F = 4.29, p = 0.02, p < 0.05). Post hoc Tukey HSD analysis determined that the significant results arose from the first experimental group in comparison to the control (D = -0.83, p = 0.01). No significant differences were revealed at 45° and 60°. Significant differences were also found in the Lysholm score among the groups (F = 4.75, p = 0.01, p < 0.05). Post hoc analysis determined that the above significant results arose from the first experimental group in comparison with the control (D = 7.5, p < 0.01) and from the second experimental in comparison with the control (D = 3.78, p = 0.03). Conclusion CEE showed improvements on quadriceps ART at 90° at a sequence of 3 d/w and in the Lysholm score at a

  2. Reconstructing land use history from Landsat time-series. Case study of a swidden agriculture system in Brazil

    NASA Astrophysics Data System (ADS)

    Dutrieux, Loïc P.; Jakovac, Catarina C.; Latifah, Siti H.; Kooistra, Lammert

    2016-05-01

    We developed a method to reconstruct land use history from Landsat images time-series. The method uses a breakpoint detection framework derived from the econometrics field and applicable to time-series regression models. The Breaks For Additive Season and Trend (BFAST) framework is used for defining the time-series regression models which may contain trend and phenology, hence appropriately modelling vegetation intra and inter-annual dynamics. All available Landsat data are used for a selected study area, and the time-series are partitioned into segments delimited by breakpoints. Segments can be associated to land use regimes, while the breakpoints then correspond to shifts in land use regimes. In order to further characterize these shifts, we classified the unlabelled breakpoints returned by the algorithm into their corresponding processes. We used a Random Forest classifier, trained from a set of visually interpreted time-series profiles to infer the processes and assign labels to the breakpoints. The whole approach was applied to quantifying the number of cultivation cycles in a swidden agriculture system in Brazil (state of Amazonas). Number and frequency of cultivation cycles is of particular ecological relevance in these systems since they largely affect the capacity of the forest to regenerate after land abandonment. We applied the method to a Landsat time-series of Normalized Difference Moisture Index (NDMI) spanning the 1984-2015 period and derived from it the number of cultivation cycles during that period at the individual field scale level. Agricultural fields boundaries used to apply the method were derived using a multi-temporal segmentation approach. We validated the number of cultivation cycles predicted by the method against in-situ information collected from farmers interviews, resulting in a Normalized Residual Mean Squared Error (NRMSE) of 0.25. Overall the method performed well, producing maps with coherent spatial patterns. We identified

  3. Reconstructing Land Use History from Landsat Time-Series. Case study of Swidden Agriculture Intensification in Brazil

    NASA Astrophysics Data System (ADS)

    Dutrieux, L.; Jakovac, C. C.; Siti, L. H.; Kooistra, L.

    2015-12-01

    We developed a method to reconstruct land use history from Landsat images time-series. The method uses a breakpoint detection framework derived from the econometrics field and applicable to time-series regression models. The BFAST framework is used for defining the time-series regression models which may contain trend and phenology, hence appropriately modelling vegetation intra and inter-annual dynamics. All available Landsat data are used, and the time-series are partitioned into segments delimited by breakpoints. Segments can be associated to land use regimes, while the breakpoints then correspond to shifts in regimes. To further characterize these shifts, we classified the unlabelled breakpoints returned by the algorithm into their corresponding processes. We used a Random Forest classifier, trained from a set of visually interpreted time-series profiles to infer the processes and assign labels to the breakpoints. The whole approach was applied to quantifying the number of cultivation cycles in a swidden agriculture system in Brazil. Number and frequency of cultivation cycles is of particular ecological relevance in these systems since they largely affect the capacity of the forest to regenerate after abandonment. We applied the method to a Landsat time-series of Normalized Difference Moisture Index (NDMI) spanning the 1984-2015 period and derived from it the number of cultivation cycles during that period at the individual field scale level. Agricultural fields boundaries used to apply the method were derived using a multi-temporal segmentation. We validated the number of cultivation cycles predicted against in-situ information collected from farmers interviews, resulting in a Normalized RMSE of 0.25. Overall the method performed well, producing maps with coherent patterns. We identified various sources of error in the approach, including low data availability in the 90s and sub-object mixture of land uses. We conclude that the method holds great promise for

  4. How constant momentum acceleration decouples energy and space focusing in distance-of-flight and time-of-flight mass spectrometries.

    PubMed

    Dennis, Elise A; Gundlach-Graham, Alexander W; Enke, Christie G; Ray, Steven J; Carado, Anthony J; Barinaga, Charles J; Koppenaal, David W; Hieftje, Gary M

    2013-05-01

    Resolution in time-of-flight mass spectrometry (TOFMS) is ordinarily limited by the initial energy and space distributions within an instrument's acceleration region and by the length of the field-free flight zone. With gaseous ion sources, these distributions lead to systematic flight-time errors that cannot be simultaneously corrected with conventional static-field ion-focusing devices (i.e., an ion mirror). It is known that initial energy and space distributions produce non-linearly correlated errors in both ion velocity and exit time from the acceleration region. Here we reinvestigate an old acceleration technique, constant-momentum acceleration (CMA), to decouple the effects of initial energy and space distributions. In CMA, only initial ion energies (and not their positions) affect the velocity ions gain. Therefore, with CMA, the spatial distribution within the acceleration region can be manipulated without creating ion-velocity error. The velocity differences caused by a spread in initial ion energy can be corrected with an ion mirror. We discuss here the use of CMA and independent focusing of energy and space distributions for both distance-of-flight mass spectrometry (DOFMS) and TOFMS. Performance characteristics of our CMA-DOFMS and CMA-TOFMS instrument, fitted with a glow-discharge ionization source, are described. In CMA-DOFMS, resolving powers (FWHM) of greater than 1000 are achieved for atomic ions with a flight length of 285 mm. In CMA-TOFMS, only ions over a narrow range of m/z values can be energy-focused; however, the technique offers improved resolution for these focused ions, with resolving powers of greater than 2000 for a separation distance of 350 mm.

  5. [Common paths of psychiatry and forensic medicine--history and evolution of insanity defense concept from antiquity to modern times].

    PubMed

    Bolechała, Filip

    2009-01-01

    Forensic psychiatry and psychology were in their beginnings inseparably associated with the forensic medicine, constituting one of its related branches of knowledge. Progress and development of these disciplines, education and the practical application for the purposes of the law were a contribution of a several generations of forensic pathologists in the 19th and 20th centuries. One of the major issues of common interest was opinionating on the sanity of offenders. However, the problem of criminal responsibility of the mentally ill perpetrators dates back to much earlier times and has its roots in the distant beginnings of human civilization. In this paper, the history and evolution of the insanity concept (as a circumstance excluding the guilt of the offender) were presented, from the oldest theories to ideas underlying modern codifications.

  6. Predicting Nonlinear Site Response Using Spectral Acceleration Vs PGV/Vs30: A Case History Using the Volvi-Test Site

    NASA Astrophysics Data System (ADS)

    Guéguen, Philippe

    2016-06-01

    In this study, we analyze the efficiency of the ratio between particle velocity and shear wave velocity as a strain proxy for evaluating the nonlinear seismic response of sediments. The in situ stress-strain relationships are derived from accelerometric vertical array recordings at the TST site in Volvi (Thessaloniki, Greece). First, the shear wave velocity between two successive sensors was computed by seismic interferometry and strain was computed as the velocity ratio or the relative displacement between sensors. The shear-wave velocity profile and in situ shear modulus degradation curve with strain were compared with previous studies performed at the TST site. Finally, the stress-strain relationships were derived from data recorded at the surface by extending the strain proxy and stress values to the ratio between peak ground velocity and the Vs30 parameter used for site classification, i.e. without requiring the accelerometric vertical array. Our model captures the in situ nonlinear response of the site, without consideration of azimuth or distance of the earthquakes. In conclusion, the acceleration (stress) values, based on the accelerometric response spectra instead of peak ground acceleration compared with the deformation (strain) proxy, provide an effective model of the in situ nonlinear response, providing information that can be integrated into ground motion prediction equations.

  7. A discrete time event-history approach to informative drop-out in mixed latent Markov models with covariates.

    PubMed

    Bartolucci, Francesco; Farcomeni, Alessio

    2015-03-01

    Mixed latent Markov (MLM) models represent an important tool of analysis of longitudinal data when response variables are affected by time-fixed and time-varying unobserved heterogeneity, in which the latter is accounted for by a hidden Markov chain. In order to avoid bias when using a model of this type in the presence of informative drop-out, we propose an event-history (EH) extension of the latent Markov approach that may be used with multivariate longitudinal data, in which one or more outcomes of a different nature are observed at each time occasion. The EH component of the resulting model is referred to the interval-censored drop-out, and bias in MLM modeling is avoided by correlated random effects, included in the different model components, which follow common latent distributions. In order to perform maximum likelihood estimation of the proposed model by the expectation-maximization algorithm, we extend the usual forward-backward recursions of Baum and Welch. The algorithm has the same complexity as the one adopted in cases of non-informative drop-out. We illustrate the proposed approach through simulations and an application based on data coming from a medical study about primary biliary cirrhosis in which there are two outcomes of interest, one continuous and the other binary. PMID:25227970

  8. Extended temperature-accelerated dynamics: Enabling long-time full-scale modeling of large rare-event systems

    SciTech Connect

    Bochenkov, Vladimir; Suetin, Nikolay; Shankar, Sadasivan

    2014-09-07

    A new method, the Extended Temperature-Accelerated Dynamics (XTAD), is introduced for modeling long-timescale evolution of large rare-event systems. The method is based on the Temperature-Accelerated Dynamics approach [M. Sørensen and A. Voter, J. Chem. Phys. 112, 9599 (2000)], but uses full-scale parallel molecular dynamics simulations to probe a potential energy surface of an entire system, combined with the adaptive on-the-fly system decomposition for analyzing the energetics of rare events. The method removes limitations on a feasible system size and enables to handle simultaneous diffusion events, including both large-scale concerted and local transitions. Due to the intrinsically parallel algorithm, XTAD not only allows studies of various diffusion mechanisms in solid state physics, but also opens the avenue for atomistic simulations of a range of technologically relevant processes in material science, such as thin film growth on nano- and microstructured surfaces.

  9. The Variational Principle for the Uniform Acceleration and Quasi-Spin in Two Dimensional Space-Time

    NASA Astrophysics Data System (ADS)

    Matsyuk, Roman Ya.

    2008-02-01

    The variational principle and the corresponding differential equation for geodesic circles in two dimensional (pseudo)-Riemannian space are being discovered. The relationship with the physical notion of uniformly accelerated relativistic particle is emphasized. The known form of spin-curvature interaction emerges due to the presence of second order derivatives in the expression for the Lagrange function. The variational equation itself reduces to the unique invariant variational equation of constant Frenet curvature in two dimensional (pseudo)-Euclidean geometry.

  10. Neutron Energy and Time-of-flight Spectra Behind the Lateral Shield of a High Energy Electron Accelerator Beam Dump, Part II: Monte Carlo Simulations

    SciTech Connect

    Roesler, Stefan

    2002-09-19

    Energy spectra of high-energy neutrons and neutron time-of-flight spectra were calculated for the setup of experiment T-454 performed with a NE213 liquid scintillator at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were created by the interaction a 28.7 GeV electron beam in the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shielding. In order to determine the attenuation length of high-energy neutrons additional concrete shielding of various thicknesses was placed outside the existing shielding. The calculations were performed using the FLUKA interaction and transport code. The energy and time-of-flight were recorded for the location of the detector allowing a detailed comparison with the experimental data. A generally good description of the data is achieved adding confidence to the use of FLUKA for the design of shielding for high-energy electron accelerators.

  11. Calculation of Neutron Time-of-Flight and Energy Spectra Behind Thick Shielding of an Electron Accelerator and Comparison to Experimental Data

    NASA Astrophysics Data System (ADS)

    Roesler, S.

    2002-05-01

    Energy spectra of high-energy neutrons and neutron time-of-flight spectra were calculated for the setup of experiment T-454 performed with a NE213 liquid scintillator at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were created by the interaction a 28.7 GeV electron beam in the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shielding. In order to determine the attenuation length of high-energy neutrons additional concrete shielding of various thicknesses was placed outside the existing shielding. The calculations were performed using the FLUKA interaction and transport code. The energy and time-of-flight were recorded for the location of the detector allowing a detailed comparison with the experimental data. A generally good description of the data is achieved adding confidence to the use of FLUKA for the design of shielding for high-energy electron accelerators.

  12. Calculation of Neutron Time-of-Flight and Energy Spectra Behind Thick Shielding of an Electron Accelerator and Comparison to Experimental Data

    SciTech Connect

    Roesler, Stefan

    2002-05-06

    Energy spectra of high-energy neutrons and neutron time-of-flight spectra were calculated for the setup of experiment T-454 performed with a NE213 liquid scintillator at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were created by the interaction a 28.7 GeV electron beam in the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shielding. In order to determine the attenuation length of high-energy neutrons additional concrete shielding of various thicknesses was placed outside the existing shielding. The calculations were performed using the FLUKA interaction and transport code. The energy and time-of-flight were recorded for the location of the detector allowing a detailed comparison with the experimental data. A generally good description of the data is achieved adding confidence to the use of FLUKA for the design of shielding for high-energy electron accelerators.

  13. Subduction on long time scales: Tighter constraints on mantle rheologies require cross-disciplinary engagement with subduction histories.

    NASA Astrophysics Data System (ADS)

    Sigloch, Karin; Mihalynuk, Mitchell G.

    2016-04-01

    Two observational records constrain subduction on long timescales: accretionary mountain belts at the surface and subducted lithosphere in the subsurface. Subducted slabs represent paleo-oceans and can be imaged by seismic tomography. Mountain belts consist of crustal slivers that were produced and aggregated near paleo-trenches but escaped subduction (arc terranes, accretionary complexes, ophiolites). They are mapped by regional geologists and further constrained by lab-based rock analysis methods. The strength of seismic tomography consists in relatively comprehensive spatial coverage of the mantle's slab inventory, together with established methods for probing uncertainties (image resolution). Unfortunately, subsurface imaging provides no direct constraints on slabs' ages and their deformation histories from rigid oceanic plates to lumpy velocity anomalies. Convection modelling by itself cannot remedy this shortcoming because independent observational constraints on mantle rheologies are lacking. Through dating of accretionary orogens, geology can in principle provide the subduction and slab ages that geophysics is missing. This requires a testable strategy for associating slabs with major accretionary events, and synthesis of geological inputs across vast spatial scales (1000 to 10,000 km) and time scales (10-100 million years). Orogens provide only limited spatial constraints on paleo-trenches because they record several generations of accreted terranes, usually heavily deformed, overprinted, and translated with the migrating continent. The interpretational uncertainties produced by these complexities are very nonlinear: Miss a suture in the field, and you may be missing an entire paleo-ocean - while also incorrectly attributing the associated slab. This danger is real, as we demonstrate for North American slabs and Cordilleran geology. Prevailing paleo-geographic interpretations for the Cordillera arguably miss a Jura-Cretaceous ocean, and slab geometries in

  14. Subsidence history of the city of Morelia, Mexico based on InSAR images processed as time series

    NASA Astrophysics Data System (ADS)

    Jaramillo, S. H.; Suárez, G.; López-Quiroz, P.

    2012-04-01

    The city of Morelia in central Mexico sits on lacustrine and fluvio-lacustrine deposits. Subsidence due to the extraction of water from the subsoil is evidenced by the presence of differential soil compaction, causing faulting and cracking of the ground and adjacent constructions. In order to study the subsidence history of the past nine years, twenty-eight ENVISAT Synthetic Aperture Radar (SAR) images acquired between May 2003 and September 2010 were processed using ROI_PAC. All scenes are descending orbit images. The resulting interferograms were filtered using an adaptive filter and, in order to increase coherence and signal-to-noise ratio, they were unwrapped using the "branch-cut" algorithm. A subset of the resulting interferograms was selected based on the following criteria. Only interferograms with spatial baseline of less than 400 m and a temporal baseline of less than 420 days were considered. The primary objective of our work was to determine the temporal evolution of the subsidence in different parts of the city. To this end, selected pixels are inverted in an independent manner from neighbouring pixels using a time series analysis. Preliminary results suggest that the central part of the basin, near the fault known as the "Central Camionera", the subsidence is almost constant with a value of 3 to 4 cm/yr until 2008. From this date on, the subsidence rates increase to values with an average of 7 to 8 cm/yr. This increase in the subsidence rate is clearly appreciated in the appearance of two clearly visible circular patterns from 2008 to 2010. Currently, an inversion is being conducted to obtain the overall subsidence history of the basin.

  15. 40Ar/39Ar impact ages and time-temperature argon diffusion history of the Bunburra Rockhole anomalous basaltic achondrite

    NASA Astrophysics Data System (ADS)

    Jourdan, Fred; Benedix, Gretchen; Eroglu, Ela.; Bland, Phil. A.; Bouvier, Audrey.

    2014-09-01

    -absorbing regolith blanket which, when combined with the diminishing frequency of large impacts in the solar system, protected Bunburra from subsequent major heating events. Finally we note that the total (K/Ar) resetting impact event history recorded by some of the brecciated eucrites (peak at 3.8-3.5 Ga) is similar to the large impact history recorded by the Bunburra Rockhole parent body (ca. 3.64-3.54 Ga; this study) and could indicate a similar position in the asteroid belt at that time.

  16. The Natural History of Kidney Graft Cortical Microcirculation Determined by Real-Time Contrast-Enhanced Sonography (RT-CES)

    PubMed Central

    Jiménez, Carlos; López, María Ovidia; Ros, Amaia; Aguilar, Ana; Menendez, David; Rivas, Begoña; Santana, María José; Vaca, Marco Antonio; Escuin, Fernando; Madero, Rosario; Selgas, Rafael

    2016-01-01

    Background Kidney transplantation is the therapy of choice for end-stage kidney disease. Graft’s life span is shorter than expected due in part to the delayed diagnosis of various complications, specifically those related to silent progression. It is recognized that serum creatinine levels and proteinuria are poor markers of mild kidney lesions, which results in delayed clinical information. There are many investigation looking for early markers of graft damage. Decreasing kidney graft cortical microcirculation has been related to poor prognosis in kidney transplantation. Cortical capillary blood flow (CCBF) can be measured by real-time contrast-enhanced sonography (RT-CES). Our aim was to describe the natural history of CCBF over time under diverse conditions of kidney transplantation, to explore the influence of donor conditions and recipient events, and to determine the capacity of CCBF for predicting renal function in medium term. Patients and Methods RT-CES was performed in 79 consecutive kidney transplant recipients during the first year under regular clinical practice. Cortical capillary blood flow was measured. Clinical variables were analyzed. The influence of CCBF has been determined by univariate and multivariate analysis using mixed regression models based on sequential measurements for each patient over time. We used a first-order autoregression model as the structure of the covariation between measures. The post-hoc comparisons were considered using the Bonferroni correction. Results The CCBF values varied significantly over the study periods and were significantly lower at 48 h and day 7. Brain-death donor age and CCBF levels showed an inverse relationship (r: -0.62, p<0.001). Living donors showed higher mean CCBF levels than brain-death donors at each point in the study. These significant differences persisted at month 12 (54.5 ± 28.2 vs 33.7 ± 30 dB/sec, living vs brain-death donor, respectively, p = 0.004) despite similar serum creatinine

  17. Cherenkov radiation conversion and collection considerations for a gamma bang time/reaction history diagnostic for the NIF.

    PubMed

    Herrmann, Hans W; Mack, Joseph M; Young, Carlton S; Malone, Robert M; Stoeffl, Wolfgang; Horsfield, Colin J

    2008-10-01

    Bang time and reaction history measurements are fundamental components of diagnosing inertial confinement fusion (ICF) implosions and will be essential contributors to diagnosing attempts at ignition on the National Ignition Facility (NIF). Fusion gammas provide a direct measure of fusion interaction rate without being compromised by Doppler spreading. Gamma-based gas Cherenkov detectors that convert fusion gamma rays to optical Cherenkov photons for collection by fast recording systems have been developed and fielded at Omega. These systems have established their usefulness in illuminating ICF physics in several experimental campaigns. Bang time precision better than 25 ps has been demonstrated, well below the 50 ps accuracy requirement defined by the NIF system design requirements. A comprehensive, validated numerical study of candidate systems is providing essential information needed to make a down selection based on optimization of sensitivity, bandwidth, dynamic range, cost, and NIF logistics. This paper presents basic design considerations arising from the two-step conversion process from gamma rays to relativistic electrons to UV/visible Cherenkov radiation. PMID:19044512

  18. Gamma bang time/reaction history diagnostics for the National Ignition Facility using 90 degrees off-axis parabolic mirrors.

    PubMed

    Malone, R M; Herrmann, H W; Stoeffl, W; Mack, J M; Young, C S

    2008-10-01

    Gas Cherenkov detectors (GCDs) have been used to convert fusion gamma into photons to achieve gamma bang time and reaction history measurements. The GCDs designed for OMEGA used Cassegrain reflector optics in order to fit inside a 10 in. manipulator. A novel design for the National Ignition Facility using 90 degrees off-axis parabolic mirrors will increase light collection efficiency from fusion gammas and achieve minimum time dispersion. The broadband Cherenkov light (from 200 to 800 nm) is relayed into a high-speed detector using three parabolic mirrors. Because light is collected from many source planes throughout the CO(2) gas volume, the detector is positioned at the stop position rather than at an image position. The stop diameter and its position are independent of the light-generation location along the gas cell. The current design collects light from a 100 mm diameter by 500 mm long gas volume. Optical ray tracings demonstrate how light can be collected from different angled trajectories of the Compton electrons as they fly through the CO(2) gas volume. A cluster of four channels will allow for increased dynamic range as well as for different gamma energy threshold sensitivities. PMID:19044513

  19. Gamma bang time/reaction history diagnostics for the National Ignition Facility using 90 deg. off-axis parabolic mirrors

    SciTech Connect

    Malone, R. M.; Herrmann, H. W.; Mack, J. M.; Young, C. S.; Stoeffl, W.

    2008-10-15

    Gas Cherenkov detectors (GCDs) have been used to convert fusion gamma into photons to achieve gamma bang time and reaction history measurements. The GCDs designed for OMEGA used Cassegrain reflector optics in order to fit inside a 10 in. manipulator. A novel design for the National Ignition Facility using 90 deg. off-axis parabolic mirrors will increase light collection efficiency from fusion gammas and achieve minimum time dispersion. The broadband Cherenkov light (from 200 to 800 nm) is relayed into a high-speed detector using three parabolic mirrors. Because light is collected from many source planes throughout the CO{sub 2} gas volume, the detector is positioned at the stop position rather than at an image position. The stop diameter and its position are independent of the light-generation location along the gas cell. The current design collects light from a 100 mm diameter by 500 mm long gas volume. Optical ray tracings demonstrate how light can be collected from different angled trajectories of the Compton electrons as they fly through the CO{sub 2} gas volume. A cluster of four channels will allow for increased dynamic range as well as for different gamma energy threshold sensitivities.

  20. Cherenkov radiation conversion and collection considerations for a gamma bang time/reaction history diagnostic for the NIF.

    PubMed

    Herrmann, Hans W; Mack, Joseph M; Young, Carlton S; Malone, Robert M; Stoeffl, Wolfgang; Horsfield, Colin J

    2008-10-01

    Bang time and reaction history measurements are fundamental components of diagnosing inertial confinement fusion (ICF) implosions and will be essential contributors to diagnosing attempts at ignition on the National Ignition Facility (NIF). Fusion gammas provide a direct measure of fusion interaction rate without being compromised by Doppler spreading. Gamma-based gas Cherenkov detectors that convert fusion gamma rays to optical Cherenkov photons for collection by fast recording systems have been developed and fielded at Omega. These systems have established their usefulness in illuminating ICF physics in several experimental campaigns. Bang time precision better than 25 ps has been demonstrated, well below the 50 ps accuracy requirement defined by the NIF system design requirements. A comprehensive, validated numerical study of candidate systems is providing essential information needed to make a down selection based on optimization of sensitivity, bandwidth, dynamic range, cost, and NIF logistics. This paper presents basic design considerations arising from the two-step conversion process from gamma rays to relativistic electrons to UV/visible Cherenkov radiation.

  1. Cherenkov radiation conversion and collection considerations for a gamma bang time/reaction history diagnostic for the NIF

    SciTech Connect

    Herrmann, Hans W.; Mack, Joseph M.; Young, Carlton S.; Malone, Robert M.; Stoeffl, Wolfgang; Horsfield, Colin J.

    2008-10-15

    Bang time and reaction history measurements are fundamental components of diagnosing inertial confinement fusion (ICF) implosions and will be essential contributors to diagnosing attempts at ignition on the National Ignition Facility (NIF). Fusion gammas provide a direct measure of fusion interaction rate without being compromised by Doppler spreading. Gamma-based gas Cherenkov detectors that convert fusion gamma rays to optical Cherenkov photons for collection by fast recording systems have been developed and fielded at Omega. These systems have established their usefulness in illuminating ICF physics in several experimental campaigns. Bang time precision better than 25 ps has been demonstrated, well below the 50 ps accuracy requirement defined by the NIF system design requirements. A comprehensive, validated numerical study of candidate systems is providing essential information needed to make a down selection based on optimization of sensitivity, bandwidth, dynamic range, cost, and NIF logistics. This paper presents basic design considerations arising from the two-step conversion process from {gamma} rays to relativistic electrons to UV/visible Cherenkov radiation.

  2. History of the development of the East African Rift System: A series of interpreted maps through time

    NASA Astrophysics Data System (ADS)

    Macgregor, Duncan

    2015-01-01

    This review paper presents a series of time reconstruction maps of the 'East African Rift System' ('EARS'), illustrating the progressive development of fault trends, subsidence, volcanism and topography. These maps build on previous basin specific interpretations and integrate released data from recent petroleum drilling. N-S trending EARS rifting commenced in the petroliferous South Lokichar Basin of northern Kenya in the Late Eocene to Oligocene, though there seem to be few further deep rifts of this age other than those immediately adjoining it. At various times during the Mid-Late Miocene, a series of small rifts and depressions formed between Ethiopia and Malawi, heralding the main regional rift subsidence phase and further rift propagation in the Plio-Pleistocene. A wide variation is thus seen in the ages of initiation of EARS basins, though the majority of fault activity, structural growth, subsidence, and associated uplift of East Africa seem to have occurred in the last 5-9 Ma, and particularly in the last 1-2 Ma. These perceptions are key to our understanding of the influence of the diverse tectonic histories on the petroleum prospectivity of undrilled basins.

  3. Idaho Completion Project’s Accelerated Retrieval Project Overview of the Pit 4 Non-Time Critical Removal Action

    SciTech Connect

    T. L. Clements; R. E. Arbon; B. D. Preussner

    2005-02-01

    This paper presents an overview of the Accelerated Retrieval Project performed by the Idaho Completion Project at the Idaho National Laboratory (INL). Topics include an overall description of the process and methods that will retrieve, characterize, and certify newly generated transuranic (TRU) waste for disposal at the Waste Isolation Pilot Plant (WIPP). The retrieval and characterization of buried TRU waste presents unique challenges. Innovative approaches developed and discussed are: excavation, RCRA waste sampling, visual examination, and deployment of the WIPP Central Characterization Project mobile systems to the INL.

  4. Production of Multi-Terawatt Time-Structured CO{sub 2} Laser Pulses for Ion Acceleration

    SciTech Connect

    Haberberger, Dan; Tochitsky, Sergei; Gong Chao; Joshi, Chan

    2010-11-04

    The UCLA Neptune Laboratory CO{sub 2} laser system has been recently upgraded to produce 3ps multi-terawatt 10{mu}m laser pulses. The laser energy is distributed over several 3 ps pulses separated by 18 ps. These temporally structured pulses are applied for laser driven ion acceleration in an H{sub 2} gas jet at a measured plasma density of 2x10{sup 19} cm{sup -3}. Protons in excess of 20 MeV have been observed in the forward direction and with energy spreads ({Delta}E/E{approx}10%).

  5. A novel adaptive time stepping variant of the Boris–Buneman integrator for the simulation of particle accelerators with space charge

    SciTech Connect

    Toggweiler, Matthias; Adelmann, Andreas; Arbenz, Peter; Yang, Jianjun

    2014-09-15

    We show that adaptive time stepping in particle accelerator simulation is an enhancement for certain problems. The new algorithm has been implemented in the OPAL (Object Oriented Parallel Accelerator Library) framework. The idea is to adjust the frequency of costly self-field calculations, which are needed to model Coulomb interaction (space charge) effects. In analogy to a Kepler orbit simulation that requires a higher time step resolution at the close encounter, we propose to choose the time step based on the magnitude of the space charge forces. Inspired by geometric integration techniques, our algorithm chooses the time step proportional to a function of the current phase space state instead of calculating a local error estimate like a conventional adaptive procedure. Building on recent work, a more profound argument is given on how exactly the time step should be chosen. An intermediate algorithm, initially built to allow a clearer analysis by introducing separate time steps for external field and self-field integration, turned out to be useful by its own, for a large class of problems.

  6. Fiber Accelerating Structures

    SciTech Connect

    Hammond, Andrew P.; /Reed Coll. /SLAC

    2010-08-25

    One of the options for future particle accelerators are photonic band gap (PBG) fiber accelerators. PBG fibers are specially designed optical fibers that use lasers to excite an electric field that is used to accelerate electrons. To improve PBG accelerators, the basic parameters of the fiber were tested to maximize defect size and acceleration. Using the program CUDOS, several accelerating modes were found that maximized these parameters for several wavelengths. The design of multiple defects, similar to having closely bound fibers, was studied to find possible coupling or the change of modes. The amount of coupling was found to be dependent on distance separated. For certain distances accelerating coupled modes were found and examined. In addition, several non-periodic fiber structures were examined using CUDOS. The non-periodic fibers produced several interesting results and promised more modes given time to study them in more detail.

  7. On the role of local CIR-associated particle acceleration in formation of time-intensity profiles of suprathermal particle fluxes

    NASA Astrophysics Data System (ADS)

    Khabarova, Olga; Malandraki, Olga E.

    2015-04-01

    A possibility of local acceleration of particles up to several MeV at the edge of corotating interaction regions (CIRs) in the solar wind is discussed. Recently, evidence for significant local particle energization due to magnetic reconnection that occurs at the heliospheric current sheet (HCS) and followed by consequent trapping and re-acceleration of suprathermal particles in magnetic islands surrounding the rippled HCS was provided (Khabarova et al. 2014). We investigate this phenomenon in application to particle energization at current sheets of various scales (from the HCS to local small-scale current sheets), including current sheets frequently observed at the edge of CIRs, and explore the role of magnetic islands in the picture of suprathermal particle flux enhancements associated with CIRs. It is commonly believed that CIRs serve as one of the sources of suprathermal particles at the Earth's orbit in addition to flares and pre-CME shocks because of particle acceleration by reverse shocks formed beyond 2-3AU. However, this paradigm demands a free way of particles back from the shocks to 1 AU, which produces specific timing and ion/electron flux features that are not observed every time. We suggest that local particle acceleration may take place directly at the CIR edge in the case of the HCS-CIR interaction, as well as be determined by the occurrence of electric field in merging/contracting magnetic islands and local reconnecting current sheets (Zank et al. 2014) in the turbulent plasma of CIRs. Multi-spacecraft data analysis (STEREO, Wind, ACE and Ulysses) is performed. Khabarova O., Zank G.P., Li G., le Roux J.A., Webb G.M., Dosch A., Zharkova V.V. and Malandraki O.E., Small-scale magnetic islands in the solar wind and their role in particle acceleration. Part 1: Dynamics of magnetic islands near the heliospheric current sheet. Submitted to ApJ, 2014 Zank G.P., le Roux J.A., Webb G.M., Dosch A., and O. Khabarova. Particle acceleration via reconnection

  8. Particle acceleration in flares

    NASA Technical Reports Server (NTRS)

    Benz, Arnold O.; Kosugi, Takeo; Aschwanden, Markus J.; Benka, Steve G.; Chupp, Edward L.; Enome, Shinzo; Garcia, Howard; Holman, Gordon D.; Kurt, Victoria G.; Sakao, Taro

    1994-01-01

    Particle acceleration is intrinsic to the primary energy release in the impulsive phase of solar flares, and we cannot understand flares without understanding acceleration. New observations in soft and hard X-rays, gamma-rays and coherent radio emissions are presented, suggesting flare fragmentation in time and space. X-ray and radio measurements exhibit at least five different time scales in flares. In addition, some new observations of delayed acceleration signatures are also presented. The theory of acceleration by parallel electric fields is used to model the spectral shape and evolution of hard X-rays. The possibility of the appearance of double layers is further investigated.

  9. Generation and application of a standardized load-time history to tubular T-joints in offshore platforms

    NASA Astrophysics Data System (ADS)

    Li, Shan-shan; Cui, Wei-cheng

    2015-10-01

    Marine structures are mostly made of metals and always experience complex random loading during their service periods. The fatigue crack growth behaviors of metal materials have been proved from laboratory tests to be sensitive to the loading sequence encountered. In order to take account of the loading sequence effect, fatigue life prediction should be based on fatigue crack propagation (FCP) theory rather than the currently used cumulative fatigue damage (CFD) theory. A unified fatigue life prediction (UFLP) method for marine structures has been proposed by the authors' group. In order to apply the UFLP method for newly designed structures, authorities such as the classification societies should provide a standardized load-time history (SLH) such as the TWIST and FALSTAFF sequences for transport and fighter aircraft. This paper mainly aims at proposing a procedure to generate the SLHs for marine structures based on a short-term loading sample and to provide an illustration on how to use the presented SLH to a typical tubular T-joint in an offshore platform based on the UFLP method.

  10. Circadian timing in central and peripheral tissues in a migratory songbird: dependence on annual life-history states.

    PubMed

    Singh, Devraj; Trivedi, Amit Kumar; Rani, Sangeeta; Panda, Satchidananda; Kumar, Vinod

    2015-10-01

    Predictable seasonal change in photoperiod triggers a sequential change in the daily activity-rest pattern, adaptive for migration in several bird species. The night-migratory black-headed bunting (Emberiza melanocephala) is day active under short photoperiods (8 h light:16 h dark, short day sensitive). Under long photoperiods (16 h light:8 h dark), the buntings are initially day active (long day premigratory) but subsequently become intensely night active (long day migratory) and after few weeks again return to a day active pattern (long day refractory). However, it is unclear how the daily expression of circadian genes changes during photoperiod-induced seasonal life-history states (LHSs). We measured period 2 (Per2), cryptochrome 1 (Cry1), brain and muscle arnt-like protein 1 (Bmal1), and circadian locomotor output cycles kaput (Clock) mRNA expressions in various neural and peripheral tissues of buntings in different LHSs and discovered differences of ∼2 to 6 h in the phase and 2- to 4-fold in amplitude of circadian oscillations of Per2, Cry1, and Bmal1 between photoperiod-induced LHSs. Phase relationship in mRNA oscillations was altered between oscillator components in the circadian pacemaker system (retina, pineal, hypothalamus) as well as in the peripheral (liver, muscle) tissues. These results show for the first time altered waveforms of clock gene expressions in all tissues in parallel with behavioral shifts and suggest the involvement of circadian system in photoperiod induction of seasonal LHSs in a migratory species.

  11. Clover root exudate produces male-biased sex ratios and accelerates male metamorphic timing in wood frogs.

    PubMed

    Lambert, Max R

    2015-12-01

    In amphibians, abnormal metamorph sex ratios and sexual development have almost exclusively been considered in response to synthetic compounds like pesticides or pharmaceuticals. However, endocrine-active plant chemicals (i.e. phytoestrogens) are commonly found in agricultural and urban waterways hosting frog populations with deviant sexual development. Yet the effects of these compounds on amphibian development remain predominantly unexplored. Legumes, like clover, are common in agricultural fields and urban yards and exude phytoestrogen mixtures from their roots. These root exudates serve important ecological functions and may also be a source of phytoestrogens in waterways. I show that clover root exudate produces male-biased sex ratios and accelerates male metamorphosis relative to females in low and intermediate doses of root exudate. My results indicate that root exudates are a potential source of contaminants impacting vertebrate development and that humans may be cultivating sexual abnormalities in wildlife by actively managing certain plant species.

  12. Clover root exudate produces male-biased sex ratios and accelerates male metamorphic timing in wood frogs.

    PubMed

    Lambert, Max R

    2015-12-01

    In amphibians, abnormal metamorph sex ratios and sexual development have almost exclusively been considered in response to synthetic compounds like pesticides or pharmaceuticals. However, endocrine-active plant chemicals (i.e. phytoestrogens) are commonly found in agricultural and urban waterways hosting frog populations with deviant sexual development. Yet the effects of these compounds on amphibian development remain predominantly unexplored. Legumes, like clover, are common in agricultural fields and urban yards and exude phytoestrogen mixtures from their roots. These root exudates serve important ecological functions and may also be a source of phytoestrogens in waterways. I show that clover root exudate produces male-biased sex ratios and accelerates male metamorphosis relative to females in low and intermediate doses of root exudate. My results indicate that root exudates are a potential source of contaminants impacting vertebrate development and that humans may be cultivating sexual abnormalities in wildlife by actively managing certain plant species. PMID:27019728

  13. Clover root exudate produces male-biased sex ratios and accelerates male metamorphic timing in wood frogs

    PubMed Central

    Lambert, Max R.

    2015-01-01

    In amphibians, abnormal metamorph sex ratios and sexual development have almost exclusively been considered in response to synthetic compounds like pesticides or pharmaceuticals. However, endocrine-active plant chemicals (i.e. phytoestrogens) are commonly found in agricultural and urban waterways hosting frog populations with deviant sexual development. Yet the effects of these compounds on amphibian development remain predominantly unexplored. Legumes, like clover, are common in agricultural fields and urban yards and exude phytoestrogen mixtures from their roots. These root exudates serve important ecological functions and may also be a source of phytoestrogens in waterways. I show that clover root exudate produces male-biased sex ratios and accelerates male metamorphosis relative to females in low and intermediate doses of root exudate. My results indicate that root exudates are a potential source of contaminants impacting vertebrate development and that humans may be cultivating sexual abnormalities in wildlife by actively managing certain plant species. PMID:27019728

  14. Time development of high-altitude auroral acceleration region plasma, potentials, and field-aligned current systems observed by Cluster during a substorm

    NASA Astrophysics Data System (ADS)

    Hull, A. J.; Chaston, C. C.; Fillingim, M. O.; Mozer, F.; Frey, H. U.

    2013-12-01

    The auroral acceleration region is an integral link in the chain of events that transpire during substorms, and the currents, plasma and electric fields undergo significant changes driven by complex dynamical processes deep in the magnetotail. These auroral acceleration processes in turn accelerate and heat the plasma that ultimately leads to some of the most intense global substorm auroral displays. The complex interplay between field-aligned current system formation, the development of parallel electric fields, and resultant changes in the plasma constituents that occur during substorms within or just above the auroral acceleration zone remain unclear. We present Cluster multi-point observations within the high-altitude acceleration region (> 3 Re altitude) at key instances during the development of a substorm. Of particular emphasis is on the time-development of the plasma, potentials and currents that occur therein with the aim of ascertaining high-altitude drivers of substorm active auroral acceleration processes and auroral emission consequences. Preliminary results show that the initial onset is dominated by Alfvenic activity as evidenced by the sudden occurrence of relatively intense, short-spatial scale Alfvenic currents and attendant energy dispersed, counterstreaming electrons poleward of the growth-phase arc. The Alfvenic currents are locally planar structures with characteristic thicknesses on the order of a few tens of kilometers. In subsequent passages by the other spacecraft, the plasma sheet region became hotter and thicker via the injection of new hot, dense plasma of magnetospheric origins poleward of the pre-existing growth phase arc. In association with the heating and/or thickening of the plasma sheet, the currents appeared to broaden to larger scales as Alfven dominated activity gave way to either inverted-V dominated or mixed inverted-V and Alfvenic behavior depending on location. The transition from Alfven dominated to inverted-V dominated

  15. Persistence time series analyses, complexity applied to natural hazards and the Quaternary lake history of the Lerma Valley, NW Argentina

    NASA Astrophysics Data System (ADS)

    Malamud, Bruce D.

    This dissertation explores the Quaternary history of a NW Argentina valley, persistence in synthetic self-affine time series, and complexity applied to natural hazards. Chapter one is an introduction. Chapter two examines the Lerma Valley in NW Argentina, today an externally drained basin which in the past was partially closed and contained a large fresh-water lake. Using geologic fieldwork laboratory work, and historical data analysis, we find that the lake was extant 1-50 ky during the period 0.78-0.1 Ma, had a surface area of 800-1300 kmsp2 and sedimentation rates of 1-10 m/ky. Modern denudation rates could supply enough sediment from the drainage to account for these rates, and the modern hydrologic regime could fill the lake with water in less than 500 years. Chapter three provides a framework to examine persistence techniques in self-affine time series. By using the Fourier spectral method, a white noise is appropriately filtered so that its power spectral density (S) depends upon frequency (f) according to S˜ fsp{-beta}. We examine fractional noises and walks with {-}3≤beta≤ 5 and Gaussian and log-normal distributions. The persistence analyses compared include autocorrelation, semivariogram, rescaled-range, Fourier power spectrum, extreme-value, and wavelet power spectrum. The last two are applied for the first time. In chapter four, self-organized critical (SOC) models are compared with actual events. The models have power-law noncumulative frequency-size distributions with exponent about 1.0, and the actual data have exponents 1.3-1.5 (forest-fires) and 2.3-3.3 (landslides). Actual forest fires are compared here for the first time with the forest-fire model; their robustness in one indicator of SOC behavior. Chapter five examines recurrence intervals of floods using power-law statistics applied to partial-duration series and the federally adopted log-Pearson type 3 (LP3) distribution applied to annual series. The great Mississippi River flood of 1993

  16. Future accelerators (?)

    SciTech Connect

    John Womersley

    2003-08-21

    I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made.

  17. Uniform acceleration in general relativity

    NASA Astrophysics Data System (ADS)

    Friedman, Yaakov; Scarr, Tzvi

    2015-10-01

    We extend de la Fuente and Romero's (Gen Relativ Gravit 47:33, 2015) defining equation for uniform acceleration in a general curved spacetime from linear acceleration to the full Lorentz covariant uniform acceleration. In a flat spacetime background, we have explicit solutions. We use generalized Fermi-Walker transport to parallel transport the Frenet basis along the trajectory. In flat spacetime, we obtain velocity and acceleration transformations from a uniformly accelerated system to an inertial system. We obtain the time dilation between accelerated clocks. We apply our acceleration transformations to the motion of a charged particle in a constant electromagnetic field and recover the Lorentz-Abraham-Dirac equation.

  18. Clinical performance of a free-breathing spatiotemporally accelerated 3-D time-resolved contrast-enhanced pediatric abdominal MR angiography

    PubMed Central

    Yousaf, Ufra; Hsiao, Albert; Cheng, Joseph Y.; Alley, Marcus T.; Lustig, Michael; Pauly, John M.; Vasanawala, Shreyas S.

    2015-01-01

    Background Pediatric contrast-enhanced MR angiography is often limited by respiration, other patient motion and compromised spatiotemporal resolution. Objective To determine the reliability of a free-breathing spatiotemporally accelerated 3-D time-resolved contrast enhanced MR angiography method for depicting abdominal arterial anatomy in young children. Materials and methods With IRB approval and informed consent, we retrospectively identified 27 consecutive children (16 males and 11 females; mean age: 3.8 years, range: 14 days to 8.4 years) referred for contrast enhanced MR angiography at our institution, who had undergone free-breathing spatiotemporally accelerated time-resolved contrast enhanced MR angiography studies. An radio-frequency-spoiled gradient echo sequence with Cartesian variable density k-space sampling and radial view ordering, intrinsic motion navigation and intermittent fat suppression was developed. Images were reconstructed with soft-gated parallel imaging locally low-rank method to achieve both motion correction and high spatiotemporal resolution. Quality of delineation of 13 abdominal arteries in the reconstructed images was assessed independently by two radiologists on a five-point scale. Ninety-five percent confidence intervals of the proportion of diagnostically adequate cases were calculated. Interobserver agreements were also analyzed. Results Eleven out of 13 arteries achieved acceptable image quality (mean score range: 3.9–5.0) for both readers. Fair to substantial interobserver agreement was reached on nine arteries. Conclusion Free-breathing spatiotemporally accelerated 3-D time-resolved contrast enhanced MR angiography frequently yields diagnostic image quality for most abdominal arteries for pediatric contrast enhanced MR angiography. PMID:26040509

  19. Straight Metalworking Fluids and All-Cause and Cardiovascular Mortality Analyzed by Using G-Estimation of an Accelerated Failure Time Model With Quantitative Exposure: Methods and Interpretations.

    PubMed

    Picciotto, Sally; Ljungman, Petter L; Eisen, Ellen A

    2016-04-01

    Straight metalworking fluids have been linked to cardiovascular mortality in analyses using binary exposure metrics, accounting for healthy worker survivor bias by using g-estimation of accelerated failure time models. A cohort of 38,666 Michigan autoworkers was followed (1941-1994) for mortality from all causes and ischemic heart disease. The structural model chosen here, using continuous exposure, assumes that increasing exposure from 0 to 1 mg/m(3) in any single year would decrease survival time by a fixed amount. Under that assumption, banning the fluids would have saved an estimated total of 8,468 (slope-based 95% confidence interval: 2,262, 28,563) person-years of life in this cohort. On average, 3.04 (slope-based 95% confidence interval: 0.02, 25.98) years of life could have been saved for each exposed worker who died from ischemic heart disease. Estimates were sensitive to both model specification for predicting exposure (multinomial or logistic regression) and characterization of exposure as binary or continuous in the structural model. Our results provide evidence supporting the hypothesis of a detrimental relationship between straight metalworking fluids and mortality, particularly from ischemic heart disease, as well as an instructive example of the challenges in obtaining and interpreting results from accelerated failure time models using a continuous exposure in the presence of competing risks. PMID:26968943

  20. History of medical radionuclide production.

    PubMed

    Ice, R D

    1995-11-01

    Radionuclide production for medical use originally was incidental to isotope discoveries by physicists and chemists. Once the available radionuclides were identified they were evaluated for potential medical use. Hevesy first used 32P in 1935 to study phosphorous metabolism in rats. Since that time, the development of cyclotrons, linear accelerators, and nuclear reactors have produced hundreds of radionuclides for potential medical use. The history of medical radionuclide production represents an evolutionary, interdisciplinary development of applied nuclear technology. Today the technology is represented by a mature industry and provides medical benefits to millions of patients annually.

  1. The Dielectric Wall Accelerator

    SciTech Connect

    Caporaso, George J.; Chen, Yu-Jiuan; Sampayan, Stephen E.

    2009-01-01

    The Dielectric Wall Accelerator (DWA), a class of induction accelerators, employs a novel insulating beam tube to impress a longitudinal electric field on a bunch of charged particles. The surface flashover characteristics of this tube may permit the attainment of accelerating gradients on the order of 100 MV/m for accelerating pulses on the order of a nanosecond in duration. A virtual traveling wave of excitation along the tube is produced at any desired speed by controlling the timing of pulse generating modules that supply a tangential electric field to the tube wall. Because of the ability to control the speed of this virtual wave, the accelerator is capable of handling any charge to mass ratio particle; hence it can be used for electrons, protons and any ion. The accelerator architectures, key technologies and development challenges will be described.

  2. Switched matrix accelerator

    SciTech Connect

    Whittum, David H.; Tantawi, Sami G.

    2001-01-01

    We describe a new concept for a microwave circuit functioning as a charged-particle accelerator at mm wavelengths, permitting an accelerating gradient higher than conventional passive circuits can withstand consistent with cyclic fatigue. The device provides acceleration for multiple bunches in parallel channels, and permits a short exposure time for the conducting surface of the accelerating cavities. Our analysis includes scalings based on a smooth transmission line model and a complementary treatment with a coupled-cavity simulation. We also provide an electromagnetic design for the accelerating structure, arriving at rough dimensions for a seven-cell accelerator matched to standard waveguide and suitable for bench tests at low power in air at 91.392 GHz. A critical element in the concept is a fast mm-wave switch suitable for operation at high power, and we present the considerations for implementation in an H-plane tee. We discuss the use of diamond as the photoconductor switch medium.

  3. Switched Matrix Accelerator

    SciTech Connect

    Whittum, David H

    2000-10-04

    We describe a new concept for a microwave circuit functioning as a charged-particle accelerator at mm-wavelengths, permitting an accelerating gradient higher than conventional passive circuits can withstand consistent with cyclic fatigue. The device provides acceleration for multiple bunches in parallel channels, and permits a short exposure time for the conducting surface of the accelerating cavities. Our analysis includes scalings based on a smooth transmission line model and a complementary treatment with a coupled-cavity simulation. We provide also an electromagnetic design for the accelerating structure, arriving at rough dimensions for a seven-cell accelerator matched to standard waveguide and suitable for bench tests at low power in air at 91.392. GHz. A critical element in the concept is a fast mm-wave switch suitable for operation at high-power, and we present the considerations for implementation in an H-plane tee. We discuss the use of diamond as the photoconductor switch medium.

  4. Microelectromechanical acceleration-sensing apparatus

    DOEpatents

    Lee, Robb M.; Shul, Randy J.; Polosky, Marc A.; Hoke, Darren A.; Vernon, George E.

    2006-12-12

    An acceleration-sensing apparatus is disclosed which includes a moveable shuttle (i.e. a suspended mass) and a latch for capturing and holding the shuttle when an acceleration event is sensed above a predetermined threshold level. The acceleration-sensing apparatus provides a switch closure upon sensing the acceleration event and remains latched in place thereafter. Examples of the acceleration-sensing apparatus are provided which are responsive to an acceleration component in a single direction (i.e. a single-sided device) or to two oppositely-directed acceleration components (i.e. a dual-sided device). A two-stage acceleration-sensing apparatus is also disclosed which can sense two acceleration events separated in time. The acceleration-sensing apparatus of the present invention has applications, for example, in an automotive airbag deployment system.

  5. The Effects of Acceleration Noise Performance on the Determination of the Earth's Time-varying Gravity Field for Low-low satellite-to-satellite Tracking missions.

    NASA Astrophysics Data System (ADS)

    Hong, S. H.; Conklin, J. W.

    2015-12-01

    GRACE provides monthly average gravity field solutions in spherical harmonic coefficients, which gives us information about land and ocean mass variations with a spatial resolution of 1 degree and with an accuracy within 2 cm throughout the entire Earth. GRACE-FO is expected to be launched in 2017 to continue the work of GRACE and to test a new laser ranging interferometer (LRI) which measures the range between the two satellites with higher precision than the K-Band ranging system used in GRACE. Moreover, there have been simulation studies that show that an additional pair of satellites in an inclined orbit increases the sampling frequency and reduces temporal aliasing errors. On the other hand, GOCE used an electrostatic gravity gradiometer and a drag-free control system to compensate for the non-gravitational forces which had better performance than the electrostatic accelerometers of GRACE. Given the fact that future missions will likely continue to use the low-low satellite-to-satellite tracking formation with LRI onboard, it is expected that acceleration noise caused by non-gravitational forces will become a limiting factor for the time-varying gravity field solution. This research evaluates the effects of acceleration noise on the estimation of the time-varying gravity field for a single pair and the optimal double pairs of satellites, assuming that the satellites fly in collinear pairs with LRI. Spherical harmonic coefficients are used to represent the solution and a batch computation Kalman filter is used to estimate the solutions. Various levels of residual noise for existing drag-free systems are applied as acceleration noise to find suitable drag-free performance requirements for upcoming geodesy missions.

  6. One-Year Follow-Up of Suicidal Adolescents: Parental History of Mental Health Problems and Time to Post-Hospitalization Attempt

    ERIC Educational Resources Information Center

    King, Cheryl A.; Kerr, David C. R.; Passarelli, Michael N.; Foster, Cynthia Ewell; Merchant, Christopher R.

    2010-01-01

    This longitudinal study of recently hospitalized suicidal youth examined parental mental health history in addition to several indices of adolescent functioning as risk factors for time-to-suicide attempt over a 1-year period. Participants were 352 adolescents (253 girls, 99 boys; ages 13-17 years) who participated in self-report and interview…

  7. Arguing History

    ERIC Educational Resources Information Center

    Clary, Renee; Wandersee, James

    2013-01-01

    The history of science illustrates some exciting--and sometimes controversial--moments. Unfortunately, textbooks tend to focus on results in a scientific discipline and only occasionally showcase an interesting historical vignette, telling the story behind those results. Although required studies may leave teachers little classroom time for…

  8. Minting History.

    ERIC Educational Resources Information Center

    Kohl, Gary

    2003-01-01

    Presents a project where fourth-grade students depicted images on coins to reflect important conflicts in Canadian history, such as September 11, 2001. Explains how to create the coins in detail. States that the students each wrote a "proclamation" that described their time period depicted on the coins. (CMK)

  9. Real-time dual-mode standard/complex Fourier-domain OCT system using graphics processing unit accelerated 4D signal processing and visualization

    NASA Astrophysics Data System (ADS)

    Zhang, Kang; Kang, Jin U.

    2011-03-01

    We realized a real-time dual-mode standard/complex Fourier-domain optical coherence tomography (FD-OCT) system using graphics processing unit (GPU) accelerated 4D (3D+time) signal processing and visualization. For both standard and complex FD-OCT modes, the signal processing tasks were implemented on a dual-GPUs architecture that included λ-to-k spectral re-sampling, fast Fourier transform (FFT), modified Hilbert transform, logarithmic-scaling, and volume rendering. The maximum A-scan processing speeds achieved are >3,000,000 line/s for the standard 1024-pixel-FD-OCT, and >500,000 line/s for the complex 1024-pixel-FD-OCT. Multiple volumerendering of the same 3D data set were preformed and displayed with different view angles. The GPU-acceleration technique is highly cost-effective and can be easily integrated into most ultrahigh speed FD-OCT systems to overcome the 3D data processing and visualization bottlenecks.

  10. Neutron energy and time-of-flight spectra behind the lateral shield of a high energy electron accelerator beam dump. Part II: Monte Carlo simulations

    NASA Astrophysics Data System (ADS)

    Roesler, S.; Liu, J. C.; Rokni, S. H.; Taniguchi, S.

    2003-05-01

    Energy spectra of high-energy neutrons and neutron time-of-flight spectra were calculated for the setup of experiment T-454 performed with a NE213 liquid scintillator at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were created by the interaction a 28.7 GeV electron beam in the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shielding. In order to determine the attenuation length of high-energy neutrons additional concrete shielding of various thicknesses was placed outside the existing shielding. The calculations were performed using the FLUKA interaction and transport code. The energy and time-of-flight spectra were recorded for the location of the detector allowing a detailed comparison with the experimental data. A generally good description of the data is achieved adding confidence to the use of FLUKA for the design of shielding for high-energy electron accelerators.

  11. A neural network Dst index model driven by input time histories of the solar wind-magnetosphere interaction

    NASA Astrophysics Data System (ADS)

    Revallo, M.; Valach, F.; Hejda, P.; Bochníček, J.

    2014-04-01

    A model to forecast 1-hour lead Dst index is proposed. Our approach is based on artificial neural networks (ANN) combined with an analytical model of the solar wind-magnetosphere interaction. Previously, the hourly solar wind parameters have been considered in the analytical model, all of them provided by registration of the ACE satellite. They were the solar wind magnetic field component Bz, velocity V, particle density n and temperature T. The solar wind parameters have been used to compute analytically the discontinuity in magnetic field across the magnetopause, denoted as [Bt]. This quantity has been shown to be important in connection with ground magnetic field variations. The method was published, in which the weighted sum of a sequence of [Bt] was proposed to produce the value of Dst index. The maximum term in the sum, possessing the maximum weight, is the one denoting the contribution of the current state of the near-Earth solar wind. The role of the older states is less important - the weights exponentially decay. Moreover, the terms turn to zero if Bz⪯0. In this study, we set up a more comprehensive model on the basis of the ANNs. The model is driven by input time histories of the discontinuity in magnetic field [Bt], which are provided by the analytical model. At the output of such revised model, the Dst index is obtained and compared with the real data records. In this way we replaced those exponential weights in the published method with another set of weights determined by the neural networks. We retrospectively tested our models with real data from solar cycle 23. The ANN approach provided better results than a simple method based on exponentially decaying weights. Moreover, we have shown that our ANN model could be used to predict Dst 1 h ahead. We assessed the predictive capability of the model with a set of independent events and found correlation coefficient CC=0.74±0.13 and prediction efficiency PE=0.44±0.15. We also compared our model with

  12. Time To Learn: A Study of the Educational Histories of Incarcerated Juveniles. Preliminary Report to [the] Illinois General Assembly.

    ERIC Educational Resources Information Center

    Kyle, Charles; And Others

    In 1990-91, the educational histories of incarcerated juveniles in Illinois were analyzed to assess the value of educational intervention strategies prior to incarceration. Following open-ended interviews with public officials, structured interviews were held with 200 juvenile offenders, of whom 50 were female, from all parts of the state. The…

  13. We Love Our Public Schools: Art Teachers' Life Histories in a Time of Loss, Accountability, and New Commonalities

    ERIC Educational Resources Information Center

    Trafí-Prats, Laura; Woywod, Christine

    2013-01-01

    This article is a Teachers' Life History study that centers on the context derived from current policies and budget cuts implemented to public services and education in the city of Milwaukee, Wisconsin. It explores how these affect the lives, moral commitments, and social senses of pedagogy of three art education specialists who have…

  14. So Many Choices, So Little Time: Strategies for Understanding and Taking Multiple-Choice Exams in History

    ERIC Educational Resources Information Center

    Blackey, Robert

    2009-01-01

    Learning as much as possible about what to expect and how best to select among response choices enables students to improve their scores so as to reflect more fully their knowledge and abilities, whether taking the SAT, ACT, AP history exams, multiple-choice exams in college courses, the GRE, or any other standardized examinations that include…

  15. Accelerating Ground-Test Cycle Time: The Six-Minute Model Change and Other Visions for the 21st Century

    NASA Technical Reports Server (NTRS)

    Kegelman, Jerome T.

    1998-01-01

    The advantage of managing organizations to minimize product development cycle time has been well established. This paper provides an overview of the wind tunnel testing cycle time reduction activities at Langley Research Center (LaRC) and gives the status of several improvements in the wind tunnel productivity and cost reductions that have resulted from these activities. Processes have been examined and optimized. Metric data from monitoring processes provides guidance for investments in advanced technologies. The most promising technologies under implementation today include the use of formally designed experiments, a diverse array of quick disconnect technology and the judicious use of advanced electronic and information technologies.

  16. Accelerated autoantibody clearance by intravenous immunoglobulin therapy: studies in experimental models to determine the magnitude and time course of the effect.

    PubMed

    Bleeker, W K; Teeling, J L; Hack, C E

    2001-11-15

    Recently, it has been postulated that the beneficial effect of intravenous immunoglobulins (IVIGs) in antibody-mediated autoimmune disorders is based on accelerated catabolism of autoantibodies. In the current study, in vivo experiments were performed with mice in which autoantibody production was mimicked by continuous infusion of monoclonal antibodies. In this model, a single dose of IVIG reduced the plasma concentrations of the infused immunoglobulin (Ig)G1 monoclonal antibody (mAb) by approximately 40% after 3 days, whereas the concentration of an IgA mAb was not affected. To extrapolate these findings to humans, a computational model for IgG clearance was established that accurately predicted the time course and magnitude of the decrease in IgG plasma levels observed in mice. Adapted for humans, this model predicted a gradually occurring decrease in autoantibody levels after IVIG administration (2 g/kg), with a maximum reduction of approximately 25% after 3 to 4 weeks and a continued decrease of several months. In conclusion, a single high dose of IVIG induces a relatively small but long-lasting reduction of autoantibody levels by accelerated IgG clearance. This mechanism has clinical relevance in the sense that it can fully explain, as the sole mechanism, the gradual decrease in autoantibody levels observed in several patient studies. However, in some clinical studies, larger or more rapid effects have been observed that cannot be explained by accelerated clearance. Hence, IVIG can also reduce autoantibody levels through mechanisms such as down-regulation of antibody production or neutralization by anti-idiotypic antibodies.

  17. Blip decomposition of the path integral: Exponential acceleration of real-time calculations on quantum dissipative systems

    SciTech Connect

    Makri, Nancy

    2014-10-07

    The real-time path integral representation of the reduced density matrix for a discrete system in contact with a dissipative medium is rewritten in terms of the number of blips, i.e., elementary time intervals over which the forward and backward paths are not identical. For a given set of blips, it is shown that the path sum with respect to the coordinates of all remaining time points is isomorphic to that for the wavefunction of a system subject to an external driving term and thus can be summed by an inexpensive iterative procedure. This exact decomposition reduces the number of terms by a factor that increases exponentially with propagation time. Further, under conditions (moderately high temperature and/or dissipation strength) that lead primarily to incoherent dynamics, the “fully incoherent limit” zero-blip term of the series provides a reasonable approximation to the dynamics, and the blip series converges rapidly to the exact result. Retention of only the blips required for satisfactory convergence leads to speedup of full-memory path integral calculations by many orders of magnitude.

  18. Analysis techniques for residual acceleration data

    NASA Technical Reports Server (NTRS)

    Rogers, Melissa J. B.; Alexander, J. Iwan D.; Snyder, Robert S.

    1990-01-01

    Various aspects of residual acceleration data are of interest to low-gravity experimenters. Maximum and mean values and various other statistics can be obtained from data as collected in the time domain. Additional information may be obtained through manipulation of the data. Fourier analysis is discussed as a means of obtaining information about dominant frequency components of a given data window. Transformation of data into different coordinate axes is useful in the analysis of experiments with different orientations and can be achieved by the use of a transformation matrix. Application of such analysis techniques to residual acceleration data provides additional information than what is provided in a time history and increases the effectiveness of post-flight analysis of low-gravity experiments.

  19. Aging and Tennis Playing in a Coincidence-Timing Task with an Accelerating Object: The Role of Visuomotor Delay

    ERIC Educational Resources Information Center

    Lobjois, Regis; Benguigui, Nicolas; Bertsch, Jean

    2005-01-01

    The purpose of the present study was to determine whether playing a specific ball sport, such as tennis, could maintain the coincidence-timing (CT) performance of older adults at a similar level to that of younger ones. To address this question, tennis players and nonplayers of three different age ranges (ages 20-30, 60-70, and 70-80 years)…

  20. Arsenic trioxide inhibits accelerated allograft rejection mediated by alloreactive CD8(+) memory T cells and prolongs allograft survival time.

    PubMed

    Li, Chun; Guan, Tianjun; Gao, Chang; Lin, Yingying; Yan, Guoliang; Zhu, Maoshu; Lv, Chongshan; Xia, Junjie; Qi, Zhongquan

    2015-09-01

    CD8(+) memory T (Tm) cells are a significant barrier to transplant tolerance induction in alloantigen-primed recipients, and are insensitive to existing clinical immunosuppressants. Here, we studied the inhibition of CD8(+) Tm cells by arsenic trioxide (As2O3) for the first time. Alloantigen-primed CD8(+) Tm cells were transferred to T cell immunodeficient nude mice. The mice were subjected to heart allotransplantation, and treated with As2O3. The transplant survival time was determined, and the inhibitory effects of As2O3 on CD8(+) Tm cell-mediated immune rejection were assessed through serological studies and inspection of the transplanted heart and lymphoid organs. We found that As2O3 treatment prolonged the mean survival time of the graft and reduced the number of CD8(+) Tm cells in the spleen and lymph nodes. The expression of the genes encoding interleukin (IL)-2, and IFN-γ was reduced, while expression of IL-10 and transforming growth factor-β was increased in the transplant. Our findings show that As2O3 treatment inhibits allograft rejection mediated by alloreactive CD8(+) Tm cells in the mouse heart transplantation model.

  1. GPU accelerated fully space and time resolved numerical simulations of self-focusing laser beams in SBS-active media

    SciTech Connect

    Mauger, Sarah; Colin de Verdière, Guillaume; Bergé, Luc; Skupin, Stefan

    2013-02-15

    A computer cluster equipped with Graphics Processing Units (GPUs) is used for simulating nonlinear optical wave packets undergoing Kerr self-focusing and stimulated Brillouin scattering in fused silica. We first recall the model equations in full (3+1) dimensions. These consist of two coupled nonlinear Schrödinger equations for counterpropagating optical beams closed with a source equation for light-induced acoustic waves seeded by thermal noise. Compared with simulations on a conventional cluster of Central Processing Units (CPUs), GPU-based computations allow us to use a significant (16 times) larger number of mesh points within similar computation times. Reciprocally, simulations employing the same number of mesh points are between 3 and 20 times faster on GPUs than on the same number of classical CPUs. Performance speedups close to 45 are reported for isolated functions evaluating, e.g., the optical nonlinearities. Since the field intensities may reach the ionization threshold of silica, the action of a defocusing electron plasma is also addressed.

  2. Cosmology of a Friedmann-Lamaître-Robertson-Walker 3-brane, late-time cosmic acceleration, and the cosmic coincidence.

    PubMed

    Doolin, Ciaran; Neupane, Ishwaree P

    2013-04-01

    A late epoch cosmic acceleration may be naturally entangled with cosmic coincidence--the observation that at the onset of acceleration the vacuum energy density fraction nearly coincides with the matter density fraction. In this Letter we show that this is indeed the case with the cosmology of a Friedmann-Lamaître-Robertson-Walker (FLRW) 3-brane in a five-dimensional anti-de Sitter spacetime. We derive the four-dimensional effective action on a FLRW 3-brane, from which we obtain a mass-reduction formula, namely, M(P)(2) = ρ(b)/|Λ(5)|, where M(P) is the effective (normalized) Planck mass, Λ(5) is the five-dimensional cosmological constant, and ρ(b) is the sum of the 3-brane tension V and the matter density ρ. Although the range of variation in ρ(b) is strongly constrained, the big bang nucleosynthesis bound on the time variation of the effective Newton constant G(N) = (8πM(P)(2))(-1) is satisfied when the ratio V/ρ ≳ O(10(2)) on cosmological scales. The same bound leads to an effective equation of state close to -1 at late epochs in accordance with astrophysical and cosmological observations.

  3. Cosmology of a Friedmann-Lamaître-Robertson-Walker 3-brane, late-time cosmic acceleration, and the cosmic coincidence.

    PubMed

    Doolin, Ciaran; Neupane, Ishwaree P

    2013-04-01

    A late epoch cosmic acceleration may be naturally entangled with cosmic coincidence--the observation that at the onset of acceleration the vacuum energy density fraction nearly coincides with the matter density fraction. In this Letter we show that this is indeed the case with the cosmology of a Friedmann-Lamaître-Robertson-Walker (FLRW) 3-brane in a five-dimensional anti-de Sitter spacetime. We derive the four-dimensional effective action on a FLRW 3-brane, from which we obtain a mass-reduction formula, namely, M(P)(2) = ρ(b)/|Λ(5)|, where M(P) is the effective (normalized) Planck mass, Λ(5) is the five-dimensional cosmological constant, and ρ(b) is the sum of the 3-brane tension V and the matter density ρ. Although the range of variation in ρ(b) is strongly constrained, the big bang nucleosynthesis bound on the time variation of the effective Newton constant G(N) = (8πM(P)(2))(-1) is satisfied when the ratio V/ρ ≳ O(10(2)) on cosmological scales. The same bound leads to an effective equation of state close to -1 at late epochs in accordance with astrophysical and cosmological observations. PMID:25166976

  4. A WiSN node SoC with real-time image compressor and IEEE 802.15.4 MAC accelerator

    NASA Astrophysics Data System (ADS)

    Zhou, Renyan; Liu, Leibo; Yin, Shouyi; Luo, Ao; Chen, Xinkai; Wei, Shaojun

    2014-11-01

    This article presents a wireless image sensor node SoC (system-on-a-chip) for low-power wireless image sensor network (WiSN), in which camera chip interface, high-quality image compression and IEEE 802.15.4 compliant acceleration modules are integrated on chip. The proposed SoC contains a hardware-implemented real-time lossless JPEG (JPEG-LS) compression engine for Bayer Color Filter Arrays (Bayer CFA), reaching a 3.5 bits/pixel with peak signal to noise ratio (PSNR) greater than 46.3 dB and achieving a maximum 5 frames/s @16 MHz for VGA (640 × 480) colour images. The proposed hardware accelerator for IEEE 802.15.4 media access control (MAC) layer covers crucial protocol defined functions and algorithms, and reduces 45% software code in the host processor. This SoC has been fabricated in UMC 0.18 µm 1P6M CMOS process. The average power of the prototype chip is 18.2 mW at 3.0 V power supply and 16 MHz clock rate.

  5. Cosmology of a Friedmann-Lamaître-Robertson-Walker 3-Brane, Late-Time Cosmic Acceleration, and the Cosmic Coincidence

    NASA Astrophysics Data System (ADS)

    Doolin, Ciaran; Neupane, Ishwaree P.

    2013-04-01

    A late epoch cosmic acceleration may be naturally entangled with cosmic coincidence—the observation that at the onset of acceleration the vacuum energy density fraction nearly coincides with the matter density fraction. In this Letter we show that this is indeed the case with the cosmology of a Friedmann-Lamaître-Robertson-Walker (FLRW) 3-brane in a five-dimensional anti-de Sitter spacetime. We derive the four-dimensional effective action on a FLRW 3-brane, from which we obtain a mass-reduction formula, namely, MP2=ρb/|Λ5|, where MP is the effective (normalized) Planck mass, Λ5 is the five-dimensional cosmological constant, and ρb is the sum of the 3-brane tension V and the matter density ρ. Although the range of variation in ρb is strongly constrained, the big bang nucleosynthesis bound on the time variation of the effective Newton constant GN=(8πMP2)-1 is satisfied when the ratio V/ρ≳O(102) on cosmological scales. The same bound leads to an effective equation of state close to -1 at late epochs in accordance with astrophysical and cosmological observations.

  6. Intra-cyclic distance per stroke phase, velocity fluctuations and acceleration time ratio of a breaststroker's hip: a comparison between elite and nonelite swimmers at different race paces.

    PubMed

    Leblanc, H; Seifert, L; Tourny-Chollet, C; Chollet, D

    2007-02-01

    The aim of this study was to compare the intra-cyclic velocity graphs of breaststroke swimmers at two skill levels in relation to their movement phases. Two groups of nine male swimmers were videotaped underwater at three swimming race paces corresponding to their actual competitive times for the 200-m, 100-m and 50-m breaststroke. Their forward intra-cyclic hip velocity was recorded with a velocity-meter. The breaststroke cycle was divided into four phases: leg propulsion, leg-arm lag phase, arm propulsion, and arm and leg recovery. From the velocity-time data, the following parameters were computed: an index of velocity fluctuations (IVF), the distance covered during each stroke phase, and an acceleration-deceleration time ratio (ADTR). The main results showed that in both groups of swimmers, when the race pace increased, the distance covered during the leg-arm lag phase decreased, while the other swimming phases remained stable. When expressed in relative values, the percentage of distance covered during the leg-arm lag phase decreased. In nonelite swimmers, the percentage of distance covered in the other stroke phases increased significantly, while only a tendency was noted in the elite group. Elite swimmers demonstrated a higher ADTR at the 50-m pace than at their 100-m and 200-m paces. An inter-group comparison showed that elite swimmers had higher values for the IVF and ADTR, which indicated their capacity to accelerate to boost the swim and highlighted the relevancy of these factors to discriminate skill level. PMID:16835822

  7. Real-time atmospheric imaging and processing with hybrid adaptive optics and hardware accelerated lucky-region fusion (LRF) algorithm

    NASA Astrophysics Data System (ADS)

    Liu, Jony Jiang; Carhart, Gary W.; Beresnev, Leonid A.; Aubailly, Mathieu; Jackson, Christopher R.; Ejzak, Garrett; Kiamilev, Fouad E.

    2014-09-01

    Atmospheric turbulences can significantly deteriorate the performance of long-range conventional imaging systems and create difficulties for target identification and recognition. Our in-house developed adaptive optics (AO) system, which contains high-performance deformable mirrors (DMs) and the fast stochastic parallel gradient decent (SPGD) control mechanism, allows effective compensation of such turbulence-induced wavefront aberrations and result in significant improvement on the image quality. In addition, we developed advanced digital synthetic imaging and processing technique, "lucky-region" fusion (LRF), to mitigate the image degradation over large field-of-view (FOV). The LRF algorithm extracts sharp regions from each image obtained from a series of short exposure frames and fuses them into a final improved image. We further implemented such algorithm into a VIRTEX-7 field programmable gate array (FPGA) and achieved real-time video processing. Experiments were performed by combining both AO and hardware implemented LRF processing technique over a near-horizontal 2.3km atmospheric propagation path. Our approach can also generate a universal real-time imaging and processing system with a general camera link input, a user controller interface, and a DVI video output.

  8. Accelerated increase in mercury contamination in north Atlantic mesopelagic food chains as indicated by time series of seabird feathers

    SciTech Connect

    Monteiro, L.R.; Furness, R.W.

    1997-12-01

    Concentrations of mercury in the environment have increased manyfold since preindustrial times as a result of anthropogenic emissions of gaseous mercury to the atmosphere. However, most records of historical change are affected by regional inputs and evidence of global impact of human activities at pristine oceanic sites is scanty. Seabird feathers contain a valuable record showing historical trends in methylmercury contamination. Some seabirds are top predators in epipelagic and others in mesopelagic food chains and thus reflect methylmercury contamination of these ecosystems. Here, the authors report the first measurements of mercury concentrations in a time series of animals from the subtropical northeast Atlantic over the last 100 years. These data show increases in mercury levels by 1.1 to 1.9%/year in epipelagic foodchains and by 3.5 to 4.8%/year in mesopelagic food chains. While the rate of increase in the epipelagic ecosystem is in close agreement with model predictions, the higher rate in the mesopelagic ecosystem has not previously been detected. However, the latter concurs with methylmercury production below the thermocline and conveys new insights into the understanding of the anthropogenic impact in the marine cycle of mercury.

  9. Self-Organizing Hierarchical Particle Swarm Optimization with Time-Varying Acceleration Coefficients for Economic Dispatch with Valve Point Effects and Multifuel Options

    NASA Astrophysics Data System (ADS)

    Polprasert, Jirawadee; Ongsakul, Weerakorn; Dieu, Vo Ngoc

    2011-06-01

    This paper proposes a self-organizing hierarchical particle swarm optimization (SPSO) with time-varying acceleration coefficients (TVAC) for solving economic dispatch (ED) problem with non-smooth functions including multiple fuel options (MFO) and valve-point loading effects (VPLE). The proposed SPSO with TVAC is the new approach optimizer and good performance for solving ED problems. It can handle the premature convergence of the problem by re-initialization of velocity whenever particles are stagnated in the search space. To properly control both local and global explorations of the swarm during the optimization process, the performance of TVAC is included. The proposed method is tested in different ED problems with non-smooth cost functions and the obtained results are compared to those from many other methods in the literature. The results have revealed that the proposed SPSO with TVAC is effective in finding higher quality solutions for non-smooth ED problems than many other methods.

  10. Used planet: A global history

    PubMed Central

    Ellis, Erle C.; Kaplan, Jed O.; Fuller, Dorian Q.; Vavrus, Steve; Klein Goldewijk, Kees; Verburg, Peter H.

    2013-01-01

    Human use of land has transformed ecosystem pattern and process across most of the terrestrial biosphere, a global change often described as historically recent and potentially catastrophic for both humanity and the biosphere. Interdisciplinary paleoecological, archaeological, and historical studies challenge this view, indicating that land use has been extensive and sustained for millennia in some regions and that recent trends may represent as much a recovery as an acceleration. Here we synthesize recent scientific evidence and theory on the emergence, history, and future of land use as a process transforming the Earth System and use this to explain why relatively small human populations likely caused widespread and profound ecological changes more than 3,000 y ago, whereas the largest and wealthiest human populations in history are using less arable land per person every decade. Contrasting two spatially explicit global reconstructions of land-use history shows that reconstructions incorporating adaptive changes in land-use systems over time, including land-use intensification, offer a more spatially detailed and plausible assessment of our planet's history, with a biosphere and perhaps even climate long ago affected by humans. Although land-use processes are now shifting rapidly from historical patterns in both type and scale, integrative global land-use models that incorporate dynamic adaptations in human–environment relationships help to advance our understanding of both past and future land-use changes, including their sustainability and potential global effects. PMID:23630271

  11. [Reaction time tests in Leipzig, Paris and Würzburg. The Franco-German history of a psychological experiment, 1890-1910].

    PubMed

    Carroy, Jacqueline; Schmidgen, Henning

    2004-01-01

    This article diiscusses from a comparative perspective the complex history of the reaction experiment with the Hipp chronoscope, one of the central experiments of late 19th-century psychology. It focuses on Wilhelm Wundt's (1832-1920) Institute for Experimental Psychology in Leipzig and on the Paris Laboratory for Physiological Psychology at the Sorbonne, which was initially directed by Henry Beaunis (1830-1921), but soon came to be dominated by the research activities of Alfred Binet (1857-1911). When the Paris psychologists founded their Laboratory in 1889, they took the Leipzig Institute as their model. In the early 1890s they adopted the reaction time experiment that had been central to Wundt's psychology. Shortly after, they modified this experiment according to their own specific interests. For Binet, it no longer served as a method for identifying the elementary components of "general" consciousness (as in Wundt), but for classifying "individual" personalities. The methodological and technological changes that Binet introduced into the experimental practice of psychology had no immediate impact on the research work in Leipzig. However, they influenced the "Wurzburg School" of psychology under Wundt's former assistant, Oswald Külpe (1862-1915). This illustrates that the comparative history of transfers of "experimental systems" (Rheinberger) across national borders is not simply a history of mere transports. Rather, it is a history of transferences that sometimes includes surprising "re-transferences".

  12. Wakefield accelerators

    SciTech Connect

    Simpson, J.D.

    1990-01-01

    The search for new methods to accelerate particle beams to high energy using high gradients has resulted in a number of candidate schemes. One of these, wakefield acceleration, has been the subject of considerable R D in recent years. This effort has resulted in successful proof of principle experiments and in increased understanding of many of the practical aspects of the technique. Some wakefield basics plus the status of existing and proposed experimental work is discussed, along with speculations on the future of wake field acceleration. 10 refs., 6 figs.

  13. LINEAR ACCELERATOR

    DOEpatents

    Colgate, S.A.

    1958-05-27

    An improvement is presented in linear accelerators for charged particles with respect to the stable focusing of the particle beam. The improvement consists of providing a radial electric field transverse to the accelerating electric fields and angularly introducing the beam of particles in the field. The results of the foregoing is to achieve a beam which spirals about the axis of the acceleration path. The combination of the electric fields and angular motion of the particles cooperate to provide a stable and focused particle beam.

  14. Feedback between Accelerator Physicists and magnet builders

    SciTech Connect

    Peggs, S.

    1995-12-31

    Our task is not to record history but to change it. (K. Marx (paraphrased)) How should Accelerator Physicists set magnet error specifications? In a crude social model, they place tolerance limits on undesirable nonlinearities and errors (higher order harmonics, component alignments, etc.). The Magnet Division then goes away for a suitably lengthy period of time, and comes back with a working magnet prototype that is reproduced in industry. A better solution is to set no specifications. Accelerator Physicists begin by evaluating expected values of harmonics, generated by the Magnet Division, before and during prototype construction. Damaging harmonics are traded off against innocuous harmonics as the prototype design evolves, lagging one generation behind the evolution of expected harmonics. Finally, the real harmonics are quickly evaluated during early industrial production, allowing a final round of performance trade-offs, using contingency scenarios prepared earlier. This solution assumes a close relationship and rapid feedback between the Accelerator Physicists and the magnet builders. What follows is one perspective of the way that rapid feedback was used to `change history` (improve linear and dynamic aperture) at RHIC, to great benefit.

  15. ION ACCELERATOR

    DOEpatents

    Bell, J.S.

    1959-09-15

    An arrangement for the drift tubes in a linear accelerator is described whereby each drift tube acts to shield the particles from the influence of the accelerating field and focuses the particles passing through the tube. In one embodiment the drift tube is splii longitudinally into quadrants supported along the axis of the accelerator by webs from a yoke, the quadrants. webs, and yoke being of magnetic material. A magnetic focusing action is produced by energizing a winding on each web to set up a magnetic field between adjacent quadrants. In the other embodiment the quadrants are electrically insulated from each other and have opposite polarity voltages on adjacent quadrants to provide an electric focusing fleld for the particles, with the quadrants spaced sufficienily close enough to shield the particles within the tube from the accelerating electric field.

  16. Acceleration switch

    DOEpatents

    Abbin, J.P. Jr.; Devaney, H.F.; Hake, L.W.

    1979-08-29

    The disclosure relates to an improved integrating acceleration switch of the type having a mass suspended within a fluid filled chamber, with the motion of the mass initially opposed by a spring and subsequently not so opposed.

  17. Acceleration switch

    DOEpatents

    Abbin, Jr., Joseph P.; Devaney, Howard F.; Hake, Lewis W.

    1982-08-17

    The disclosure relates to an improved integrating acceleration switch of the type having a mass suspended within a fluid filled chamber, with the motion of the mass initially opposed by a spring and subsequently not so opposed.

  18. LINEAR ACCELERATOR

    DOEpatents

    Christofilos, N.C.; Polk, I.J.

    1959-02-17

    Improvements in linear particle accelerators are described. A drift tube system for a linear ion accelerator reduces gap capacity between adjacent drift tube ends. This is accomplished by reducing the ratio of the diameter of the drift tube to the diameter of the resonant cavity. Concentration of magnetic field intensity at the longitudinal midpoint of the external sunface of each drift tube is reduced by increasing the external drift tube diameter at the longitudinal center region.

  19. Wheel running can accelerate or delay extinction of conditioned place preference for cocaine in male C57BL/6J mice, depending on timing of wheel access.

    PubMed

    Mustroph, Martina L; Stobaugh, Derrick J; Miller, Daniel S; DeYoung, Erin K; Rhodes, Justin S

    2011-10-01

    Aerobic exercise may represent a useful intervention for drug abuse in predisposed individuals. Exercise increases plasticity in the brain that could be used to reverse learned drug associations. Previous studies have reported that exposing mice to a complex environment including running wheels after drug conditioning abolishes conditioned place preference (CPP) for cocaine, whereas running can enhance CPP when administered before conditioning. The purpose of the present study was to test the hypothesis that timing of exercise relative to conditioning has opposing effects on cocaine CPP. Male C57BL/6J mice experienced 30 days of running or sedentary treatments either before or after cocaine conditioning. Control animals always received saline and never cocaine, but otherwise underwent the same conditioning and exercise treatments. Animals were given bromodeoxyuridine injections at the onset of conditioning or exercise, and euthanized at the end of the study to quantify survival of new neurons in the hippocampus as a marker of plasticity. Wheel running accelerated extinction of CPP when running occurred entirely after drug conditioning, whereas running delayed extinction when administered before conditioning. A single conditioning day after running was sufficient to abolish the accelerated extinction observed when all conditioning preceded running. Running approximately doubled adult hippocampal neurogenesis, whereas cocaine had no effect. These results suggest that exercise-induced plasticity can facilitate learning that context is no longer associated with drug. However, if drug exposure occurs after exercise, running-induced plasticity may strengthen drug associations. The results provide insights into the interaction between exercise and drug conditioning that could have implications for drug abuse treatments.

  20. Application of local area networks to accelerator control systems at the Stanford Linear Accelerator

    SciTech Connect

    Fox, J.D.; Linstadt, E.; Melen, R.

    1983-03-01

    The history and current status of SLAC's SDLC networks for distributed accelerator control systems are discussed. These local area networks have been used for instrumentation and control of the linear accelerator. Network topologies, protocols, physical links, and logical interconnections are discussed for specific applications in distributed data acquisition and control system, computer networks and accelerator operations.

  1. Long-term consequences of variation in timing and manner of fry introduction on juvenile Atlantic salmon (Salmo salar) growth, survival, and life-history expression

    USGS Publications Warehouse

    Letcher, B.H.; Dubreuil, T.; O'Donnell, M. J.; Obedzinski, M.; Griswold, K.; Nislow, K.H.

    2004-01-01

    We tested the influence of introduction time and the manner of introduction on growth, survival, and life-history expression of Atlantic salmon (Salmo salar). Introduction treatments included three fry stocking times and stream rearing of embryos. Despite poor growth conditions during the early stocking period, early-stocked fish were larger throughout the entire study period, likely the result of prior residence advantage. This interpretation was reinforced by the laboratory study, where early-stocked fish outgrew late-stocked fish when reared together, but not when they were reared separately. In contrast to growth, abundance of stocked fish was greatest for fish stocked during the middle period, and this stocking group produced the greatest number of smolts. Despite smaller size, survival of stream-incubated fish was generally greater than survival of stocked fish. Introduction timing had a pronounced effect on smolt age but a weak effect on extent of parr maturation. Overall, these observations indicate that small differences (???2 weeks) in introduction time can have long-term effects on size, survival, and life-history expression. Results suggest stabilizing selection on introduction times, mediated by the interaction between prior residence (advantage to fish introduced earlier) and habitat suitability (advantage to fish introduced later). ?? 2004 NRC Canada.

  2. The Trouble with History.

    ERIC Educational Resources Information Center

    Myers, John

    1990-01-01

    Cites the problems associated with teaching history: (1) lack of consensus on what and how to teach; (2) the adult perspective from which it is taught; (3) the abstract nature of history content; and (4) the concept of time. Concludes that efforts to include adolescent knowledge, skills, and attitudes should be considered in the history program.…

  3. Life history traits in selfing versus outcrossing annuals: exploring the 'time-limitation' hypothesis for the fitness benefit of self-pollination

    PubMed Central

    Snell, Rebecca; Aarssen, Lonnie W

    2005-01-01

    Background Most self-pollinating plants are annuals. According to the 'time-limitation' hypothesis, this association between selfing and the annual life cycle has evolved as a consequence of strong r-selection, involving severe time-limitation for completing the life cycle. Under this model, selection from frequent density-independent mortality in ephemeral habitats minimizes time to flower maturation, with selfing as a trade-off, and / or selection minimizes the time between flower maturation and ovule fertilization, in which case selfing has a direct fitness benefit. Predictions arising from this hypothesis were evaluated using phylogenetically-independent contrasts of several life history traits in predominantly selfing versus outcrossing annuals from a data base of 118 species distributed across 14 families. Data for life history traits specifically related to maturation and pollination times were obtained by monitoring the start and completion of different stages of reproductive development in a greenhouse study of selfing and outcrossing annuals from an unbiased sample of 25 species involving five pair-wise family comparisons and four pair-wise genus comparisons. Results Selfing annuals in general had significantly shorter plant heights, smaller flowers, shorter bud development times, shorter flower longevity and smaller seed sizes compared with their outcrossing annual relatives. Age at first flower did not differ significantly between selfing and outcrossing annuals. Conclusions This is the first multi-species study to report these general life-history differences between selfers and outcrossers among annuals exclusively. The results are all explained more parsimoniously by selection associated with time-limitation than by selection associated with pollinator/mate limitation. The shorter bud development time reported here for selfing annuals is predicted explicitly by the time-limitation hypothesis for the fitness benefit of selfing (and not by the

  4. Timing Tricks For Complicated Accelerators

    SciTech Connect

    Bjorklund, Eric A.

    2015-11-02

    A brief description of the Los Alamos Neutron Science Center is given first, including static and dynamic scheduling. The principal tricks presented are prescient feed forward and pulser replication. Tricks with flip/flop pulsers are also included.

  5. Preliminary energy-filtering neutron imaging with time-of-flight method on PKUNIFTY: A compact accelerator based neutron imaging facility at Peking University

    NASA Astrophysics Data System (ADS)

    Wang, Hu; Zou, Yubin; Wen, Weiwei; Lu, Yuanrong; Guo, Zhiyu

    2016-07-01

    Peking University Neutron Imaging Facility (PKUNIFTY) works on an accelerator-based neutron source with a repetition period of 10 ms and pulse duration of 0.4 ms, which has a rather low Cd ratio. To improve the effective Cd ratio and thus improve the detection capability of the facility, energy-filtering neutron imaging was realized with the intensified CCD camera and time-of-flight (TOF) method. Time structure of the pulsed neutron source was firstly simulated with Geant4, and the simulation result was evaluated with experiment. Both simulation and experiment results indicated that fast neutrons and epithermal neutrons were concentrated in the first 0.8 ms of each pulse period; meanwhile in the period of 0.8-2.0 ms only thermal neutrons existed. Based on this result, neutron images with and without energy filtering were acquired respectively, and it showed that detection capability of PKUNIFTY was improved with setting the exposure interval as 0.8-2.0 ms, especially for materials with strong moderating capability.

  6. Neutron Energy and Time-of-flight Spectra Behind the Lateral Shield of a High Energy Electron Accelerator Beam Dump,Part I: Measurements

    SciTech Connect

    Roesler, Stefan

    2002-09-24

    Neutron energy and time-of-flight spectra were measured behind the lateral shield of the electron beam dump at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were produced by a 28.7 GeV electron beam hitting the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shield. The measurements were performed using a NE213 organic liquid scintillator behind different thicknesses of the concrete shield of 274 cm, 335 cm, and 396 cm, respectively. The neutron energy spectra between 6 and 800 MeV were obtained by unfolding the measured pulse height spectrum with the detector response function. The attenuation length of neutrons in concrete was then derived. The spectra of neutron time-of-flight between beam on dump and neutron detection by NE213 were also measured. The corresponding experimental results were simulated with the FLUKA Monte Carlo code. The experimental results show good agreement with the simulated results.

  7. Neutron energy and time-of-flight spectra behind the lateral shield of a high energy electron accelerator beam dump. Part I: measurements

    NASA Astrophysics Data System (ADS)

    Taniguchi, S.; Nakamura, T.; Nunomiya, T.; Iwase, H.; Yonai, S.; Sasaki, M.; Rokni, S. H.; Liu, J. C.; Kase, K. R.; Roesler, S.

    2003-05-01

    Neutron energy and time-of-flight spectra were measured behind the lateral shield of the electron beam dump at the Final Focus Test Beam (FFTB) facility at the Stanford Linear Accelerator Center. The neutrons were produced by a 28.7 GeV electron beam hitting the aluminum beam dump of the FFTB which is housed inside a thick steel and concrete shield. The measurements were performed using an NE213 organic liquid scintillator behind different thicknesses of the concrete shield of 274, 335, and 396 cm, respectively. The neutron energy spectra between 6 and 800 MeV were obtained by unfolding the measured pulse height spectrum with the detector response function. The attenuation length of neutrons in concrete was then derived. The spectra of neutron time-of-flight between beam on dump and neutron detection by NE213 were also measured. The corresponding experimental results were simulated with the FLUKA Monte Carlo code. The experimental results show good agreement with the simulated results.

  8. Large electrostatic accelerators

    SciTech Connect

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators.

  9. Accelerated molecular dynamics methods

    SciTech Connect

    Perez, Danny

    2011-01-04

    The molecular dynamics method, although extremely powerful for materials simulations, is limited to times scales of roughly one microsecond or less. On longer time scales, dynamical evolution typically consists of infrequent events, which are usually activated processes. This course is focused on understanding infrequent-event dynamics, on methods for characterizing infrequent-event mechanisms and rate constants, and on methods for simulating long time scales in infrequent-event systems, emphasizing the recently developed accelerated molecular dynamics methods (hyperdynamics, parallel replica dynamics, and temperature accelerated dynamics). Some familiarity with basic statistical mechanics and molecular dynamics methods will be assumed.

  10. Acceleration and Velocity Sensing from Measured Strain

    NASA Technical Reports Server (NTRS)

    Pak, Chan-Gi; Truax, Roger

    2015-01-01

    A simple approach for computing acceleration and velocity of a structure from the strain is proposed in this study. First, deflection and slope of the structure are computed from the strain using a two-step theory. Frequencies of the structure are computed from the time histories of strain using a parameter estimation technique together with an autoregressive moving average model. From deflection, slope, and frequencies of the structure, acceleration and velocity of the structure can be obtained using the proposed approach. Simple harmonic motion is assumed for the acceleration computations, and the central difference equation with a linear autoregressive model is used for the computations of velocity. A cantilevered rectangular wing model is used to validate the simple approach. Quality of the computed deflection, acceleration, and velocity values are independent of the number of fibers. The central difference equation with a linear autoregressive model proposed in this study follows the target response with reasonable accuracy. Therefore, the handicap of the backward difference equation, phase shift, is successfully overcome.

  11. Prehension of Half-Full and Half-Empty Glasses: Time and History Effects on Multi-Digit Coordination

    PubMed Central

    Sun, Yao; Zatsiorsky, Vladimir M.; Latash, Mark L.

    2011-01-01

    We explored how digit forces and indices of digit coordination depend on the history of getting to a particular set of task parameters during static prehension tasks. The participants held in the right hand an instrumented handle with a light-weight container attached on top of the handle. At the beginning of each trial, the container could be empty, filled to the half with water (0.4 l) or filled to the top (0.8 l). The water was pumped in/out of the container at a constant, slow rate over 10 s. At the end of each trial, the participants always held a half-filled container that has just been filled (Empty-Half), emptied (Full-Half), or stayed half-filled throughout the trial (Half-Only). Indices of co-variation (synergy indices) of elemental variables (forces and moments of force produced by individual digits) stabilizing such performance variables as total normal force, total tangetial force, and total moment of force were computed at two levels of an assumed control hierarchy. At the upper level, the task is shared between the thumb and virtual finger (an imagined digit with the mechanical action equal to that of the four fingers), while at the lower level, action of the virtual finger is shared among the actual four fingers. Filling or emptying the container led to a drop in the safety margin (proportion of grip force over the slipping threshold) below the values observed in the Half-Only condition. Synergy indices at both levels of the hierarchy showed changes over the Full-Half and Empty-Half condition. These changes could be monotonic (typical of moment of force and normal force) or non-monotonic (typical of tangential force). For both normal and tangential forces, higher synergy indices at the higher level of the hierarchy corresponded to lower indices at the lower level. Significant differences in synergy indices across conditions were seen at the final steady-state showing that digit coordination during steady holding an object is history dependent. The

  12. Do differences in life-history traits and the timing of peak mating activity between host-associated populations of Chilo suppressalis have a genetic basis?

    PubMed

    Quan, Wei-Li; Liu, Wen; Zhou, Rui-Qi; Qureshi, Sundas Rana; Ding, Nan; Ma, Wei-Hua; Lei, Chao-Liang; Wang, Xiao-Ping

    2016-07-01

    The development of host races, genetically distinct populations of the same species with different hosts, is considered to be the initial stage of ecological speciation. Ecological and biological differences consistent with host race formation have been reported between water-oat and rice-associated populations of Chilo suppressalis. In order to confirm whether these differences have a genetic basis, we conducted experiments to determine the extent to which various life-history traits and the time of peak mating activity of these populations were influenced by the species of host plant larvae were raised on. Individuals from each population were reared for three consecutive generations on either water-oat fruit pulp or rice seedlings. Descendants of both populations had higher larval survival rates, shorter larval developmental periods, higher pupal weight, and longer adult forewings, when reared on water-oats than when reared on rice. The time of peak of mating activity differed between the descendants of each population, irrespective of whether they were raised on water-oats or rice. These results indicate that although some life-history traits of host-associated populations of C. suppressalis are influenced by the host plant larvae are raised on, time of peak mating activity is not. Because it is a stable, objective, phenotypic trait, further research on difference in the time of peak mating activity between host-associated populations of C. suppressalis should be conducted to clarify the mechanism responsible for host race formation in this species. PMID:27386090

  13. Native American Students' Understanding of Geologic Time Scale: 4th-8th Grade Ojibwe Students' Understanding of Earth's Geologic History

    ERIC Educational Resources Information Center

    Nam, Younkyeong; Karahan, Engin; Roehrig, Gillian

    2016-01-01

    Geologic time scale is a very important concept for understanding long-term earth system events such as climate change. This study examines forty-three 4th-8th grade Native American--particularly Ojibwe tribe--students' understanding of relative ordering and absolute time of Earth's significant geological and biological events. This study also…

  14. Intellectual History, Social History, Cultural History...and Our History.

    ERIC Educational Resources Information Center

    Nord, David Paul

    1990-01-01

    Defines and explores the links among intellectual, social, and cultural history. Warns that an adequate foundation must be laid in the economic and institutional social history of mass media before communication historians jump into cultural history. (SR)

  15. Generation of heavy ion beams using femtosecond laser pulses in the target normal sheath acceleration and radiation pressure acceleration regimes

    NASA Astrophysics Data System (ADS)

    Petrov, G. M.; McGuffey, C.; Thomas, A. G. R.; Krushelnick, K.; Beg, F. N.

    2016-06-01

    Theoretical study of heavy ion acceleration from sub-micron gold foils irradiated by a short pulse laser is presented. Using two dimensional particle-in-cell simulations, the time history of the laser pulse is examined in order to get insight into the laser energy deposition and ion acceleration process. For laser pulses with intensity 3 × 10 21 W / cm 2 , duration 32 fs, focal spot size 5 μm, and energy 27 J, the calculated reflection, transmission, and coupling coefficients from a 20 nm foil are 80%, 5%, and 15%, respectively. The conversion efficiency into gold ions is 8%. Two highly collimated counter-propagating ion beams have been identified. The forward accelerated gold ions have average and maximum charge-to-mass ratio of 0.25 and 0.3, respectively, maximum normalized energy 25 MeV/nucleon, and flux 2 × 10 11 ions / sr . An analytical model was used to determine a range of foil thicknesses suitable for acceleration of gold ions in the radiation pressure acceleration regime and the onset of the target normal sheath acceleration regime. The numerical simulations and analytical model point to at least four technical challenges hindering the heavy ion acceleration: low charge-to-mass ratio, limited number of ions amenable to acceleration, delayed acceleration, and high reflectivity of the plasma. Finally, a regime suitable for heavy ion acceleration has been identified in an alternative approach by analyzing the energy absorption and distribution among participating species and scaling of conversion efficiency, maximum energy, and flux with laser intensity.

  16. Acceleration of cerebral ventricular expansion in the Cardiovascular Health Study.

    PubMed

    Carmichael, Owen T; Kuller, L H; Lopez, O L; Thompson, P M; Dutton, R A; Lu, A; Lee, S E; Lee, J Y; Aizenstein, H J; Meltzer, C C; Liu, Y; Toga, A W; Becker, J T

    2007-09-01

    Interactions between prevalent late-life medical conditions and expansion of the cerebral ventricles are not well understood. Thirty elderly subjects received three magnetic resonance (MR) scans each, in 1997-1999, 2002-2004, and 2003-2005. A linear expansion model of MR-measured lateral ventricle volume was estimated for each subject by fitting a line to a plot of their 1997-1999 and 2002-2004 volumes as a function of time. Acceleration in ventricular expansion was defined as the deviation between the 2003-2005 volumes measured from MR and the 2003-2005 volumes predicted by the linear expansion model. Ventricular acceleration was analyzed in a multivariate model with age, race, history of heart disease, diabetes, and hypertension as fixed effects. Ventricular acceleration was significantly higher in non-whites, diabetics, and those without heart disease (p<0.05). Ventricular acceleration was higher in subjects with a history of hypertension, but the difference was not statistically significant (p=0.08). Acceleration of ventricular expansion in the elderly may be related to demographic and cardiovascular factors.

  17. Mechanism of emplacement of the Cannibal Creek Granite with special reference to timing and deformation history of the aureole

    NASA Astrophysics Data System (ADS)

    Davis, Brett K.

    1993-09-01

    The ovoid Cannibal Creek Granite consists of a minor phase emplaced during the regional D 3 deformation and a major phase emplaced during the regional D 4 deformation. It possesses an intense contact-parallel foliation on its margin and in the adjacent porphyroblastic schist that formed through partitioning of the shearing component of deformation against the crystallized pluton margin during synchronous E-W D 4 shortening. During this process a pre-existing shallow S 3 foliation was updomed around the pluton and re-used/reactivated by D 4 shear, with associated dissolution of quartz, resulting in the formation of an ovoid closed foliation around the pluton. Thus the granite is located within a domal-shaped, approximately N-S-trending, pluton-scale F 34 antiform that formed synchronous with emplacement. Three successive stages of porphyroblast growth record the history of processes operating during progressive emplacement and the structures that developed. Space problems were solved through upward movement of the rocks above the granite due to movement on the S 4 cleavage as well as on pre-existing subvertical bedding and cleavages, and by reactivation of steep D 2 faults.

  18. Wake field acceleration experiments

    SciTech Connect

    Simpson, J.D.

    1988-01-01

    Where and how will wake field acceleration devices find use for other than, possibly, accelerators for high energy physics. I don't know that this can be responsibly answered at this time. What I can do is describe some recent results from an ongoing experimental program at Argonne which support the idea that wake field techniques and devices are potentially important for future accelerators. Perhaps this will spawn expanded interest and even new ideas for the use of this new technology. The Argonne program, and in particular the Advanced Accelerator Test Facility (AATF), has been reported in several fairly recent papers and reports. But because this is a substantially new audience for the subject, I will include a brief review of the program and the facility before describing experiments. 10 refs., 7 figs.

  19. Associations of Sedentary Behavior, Sedentary Bouts and Breaks in Sedentary Time with Cardiometabolic Risk in Children with a Family History of Obesity

    PubMed Central

    Saunders, Travis John; Tremblay, Mark Stephen; Mathieu, Marie-Ève; Henderson, Mélanie; O’Loughlin, Jennifer; Tremblay, Angelo; Chaput, Jean-Philippe

    2013-01-01

    Background Although reports in adults suggest that breaks in sedentary time are associated with reduced cardiometabolic risk, these findings have yet to be replicated in children. Purpose To investigate whether objectively measured sedentary behavior, sedentary bouts or breaks in sedentary time are independently associated with cardiometabolic risk in a cohort of Canadian children aged 8–11 years with a family history of obesity. Methods Data from 286 boys and 236 girls living in Quebec, Canada, with at least one biological parent with obesity (QUALITY cohort) were collected from 2005–2008, and analyzed in 2013. Sedentary behavior, light and moderate-to-vigorous physical activity were measured over 7 days using accelerometry. Leisure time computer/video game use and TV viewing over the past 7 days were self-reported. Outcomes included waist circumference, body mass index Z-score, fasting insulin, fasting glucose, triglycerides, HDL-cholesterol, C-reactive protein and a continuous cardiometabolic risk score. Results After adjustment for confounders, breaks in sedentary time and the number of sedentary bouts lasting 1–4 minutes were associated with reduced cardiometabolic risk score and lower BMI Z-score in both sexes (all p<0.05). The number of sedentary bouts lasting 5–9 minutes was negatively associated with waist circumference in girls only, while the number of bouts lasting 10–14 minutes was positively associated with fasting glucose in girls, and with BMI Z-score in boys (all p<0.05). Leisure time computer/video game use was associated with increased cardiometabolic risk score and waist circumference in boys, while TV viewing was associated with increased cardiometabolic risk, waist circumference, and BMI Z-score in girls (all p<0.05). Conclusions These results suggest that frequent interruptions in sedentary time are associated with a favourable cardiometabolic risk profile and highlight the deleterious relationship between screen time and

  20. 2-20 ns interframe time 2-frame 6.151 keV x-ray imaging on the recently upgraded Z Accelerator: A progress report

    SciTech Connect

    Bennett, G. R.; Smith, I. C.; Shores, J. E.; Sinars, D. B.; Robertson, G.; Atherton, B. W.; Jones, M. C.; Porter, J. L.

    2008-10-15

    When used for the production of an x-ray imaging backlighter source on Sandia National Laboratories' recently upgraded 26 MA Z Accelerator, the terawatt-class, multikilojoule, 526.57 nm Z-Beamlet laser (ZBL) [P. K. Rambo et al., Appl. Opt. 44, 2421 (2005)], in conjunction with the 6.151 keV (1s{sup 2}-1s2p triplet line of He-like Mn) curved-crystal imager [D. B. Sinars et al., Rev. Sci. Instrum. 75, 3672 (2004); G. R. Bennett et al., Rev. Sci. Instrum. 77, 10E322 (2006)], is capable of providing a high quality x radiograph per Z shot for inertial confinement fusion (ICF), complex hydrodynamics, and other high-energy-density physics experiments. For example, this diagnostic has recently afforded microgram-scale mass perturbation measurements on an imploding ignition-scale 1 mg ICF capsule [G. R. Bennett et al., Phys. Rev. Lett. 99, 205003 (2007)], where the perturbation was initiated by a surrogate deuterium-tritium (DT) fuel fill tube. Using an angle-time multiplexing technique, ZBL now has the capability to provide two spatially and temporally separated foci in the Z chamber, allowing 'two-frame' imaging to be performed, with an interframe time range of 2-20 ns. This multiplexing technique allows the full area of the four-pass amplifiers to be used for the two pulses, rather than split the amplifiers effectively into two rectangular sections, with one leg delayed with respect to the other, which would otherwise double the power imposed onto the various optics thereby halving the damage threshold, for the same irradiance on target. The 6.151 keV two frame technique has recently been used to image imploding wire arrays, using a 7.3 ns interframe time. The diagnostic will soon be converted to operate with p-rather than s-polarized laser light for enhanced laser absorption in the Mn foil, plus other changes (e.g., operation at the possibly brighter 6.181 keV Mn 1s{sup 2}-1s2p singlet line), to increase x-ray yields. Also, a highly sensitive inline multiframe ultrafast