Simulation study of the sub-terawatt laser wakefield acceleration operated in self-modulated regime

NASA Astrophysics Data System (ADS)

Hsieh, C.-Y.; Lin, M.-W.; Chen, S.-H.

2018-02-01

Laser wakefield acceleration (LWFA) can be accomplished by introducing a sub-terawatt (TW) laser pulse into a thin, high-density gas target. In this way, the self-focusing effect and the self-modulation that happened on the laser pulse produce a greatly enhanced laser peak intensity that can drive a nonlinear plasma wave to accelerate electrons. A particle-in-cell model is developed to study sub-TW LWFA when a 0.6-TW laser pulse interacts with a dense hydrogen plasma. Gas targets having a Gaussian density profile or a flat-top distribution are defined for investigating the properties of sub-TW LWFA when conducting with a gas jet or a gas cell. In addition to using 800-nm laser pulses, simulations are performed with 1030-nm laser pulses, as they represent a viable approach to realize the sub-TW LWFA driven by high-frequency, diode-pumped laser systems. The peak density which allows the laser peak power PL˜2 Pc r of self-focusing critical power is favourable for conducting sub-TW LWFA. Otherwise, an excessively high peak density can induce an undesired filament effect which rapidly disintegrates the laser field envelope and violates the process of plasma wave excitation. The plateau region of a flat-top density distribution allows the self-focusing and the self-modulation of the laser pulse to develop, from which well-established plasma bubbles can be produced to accelerate electrons. The process of electron injection is complicated in such high-density plasma conditions; however, increasing the length of the plateau region represents a straightforward method to realize the injection and acceleration of electrons within the first bubble, such that an improved LWFA performance can be accomplished.

Accelerator–Reactor Coupling for Energy Production in Advanced Nuclear Fuel Cycles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heidet, Florent; Brown, Nicholas R.; Haj Tahar, Malek

2015-01-01

This article is a review of several accelerator-reactor interface issues and nuclear fuel cycle applications of accelerator-driven subcritical systems. The systems considered here have the primary goal of energy production, but that goal is accomplished via a specific application in various proposed nuclear fuel cycles, such as breed-and-burn of fertile material or burning of transuranic material. Several basic principles are reviewed, starting from the proton beam window including the target, blanket, reactor core, and up to the fuel cycle. We focused on issues of interest, e.g. the impact of the energy required to run the accelerator and associated systems onmore » the potential electricity delivered to the grid. Accelerator-driven systems feature many of the constraints and issues associated with critical reactors, with the added challenges of subcritical operation and coupling to an accelerator. Reliable accelerator operation and avoidance of beam trips are a critically important. One interesting challenge is measurement of blanket subcriticality level during operation. We also reviewed the potential benefits of accelerator-driven systems in various nuclear fuel cycle applications. Ultimately, accelerator-driven subcritical systems with the goal of transmutation of transuranic material have lower 100,000-year radioactivity versus a critical fast reactor with recycle of uranium and plutonium.« less

Application of real-time digitization techniques in beam measurement for accelerators

NASA Astrophysics Data System (ADS)

Zhao, Lei; Zhan, Lin-Song; Gao, Xing-Shun; Liu, Shu-Bin; An, Qi

2016-04-01

Beam measurement is very important for accelerators. In this paper, modern digital beam measurement techniques based on IQ (In-phase & Quadrature-phase) analysis are discussed. Based on this method and high-speed high-resolution analog-to-digital conversion, we have completed three beam measurement electronics systems designed for the China Spallation Neutron Source (CSNS), Shanghai Synchrotron Radiation Facility (SSRF), and Accelerator Driven Sub-critical system (ADS). Core techniques of hardware design and real-time system calibration are discussed, and performance test results of these three instruments are also presented. Supported by National Natural Science Foundation of China (11205153, 10875119), Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-N27), and the Fundamental Research Funds for the Central Universities (WK2030040029),and the CAS Center for Excellence in Particle Physics (CCEPP).

Safety Criticality Standards Using the French CRISTAL Code Package: Application to the AREVA NP UO{sub 2} Fuel Fabrication Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doucet, M.; Durant Terrasson, L.; Mouton, J.

2006-07-01

Criticality safety evaluations implement requirements to proof of sufficient sub critical margins outside of the reactor environment for example in fuel fabrication plants. Basic criticality data (i.e., criticality standards) are used in the determination of sub critical margins for all processes involving plutonium or enriched uranium. There are several criticality international standards, e.g., ARH-600, which is one the US nuclear industry relies on. The French Nuclear Safety Authority (DGSNR and its advising body IRSN) has requested AREVA NP to review the criticality standards used for the evaluation of its Low Enriched Uranium fuel fabrication plants with CRISTAL V0, the recentlymore » updated French criticality evaluation package. Criticality safety is a concern for every phase of the fabrication process including UF{sub 6} cylinder storage, UF{sub 6}-UO{sub 2} conversion, powder storage, pelletizing, rod loading, assembly fabrication, and assembly transportation. Until 2003, the accepted criticality standards were based on the French CEA work performed in the late seventies with the APOLLO1 cell/assembly computer code. APOLLO1 is a spectral code, used for evaluating the basic characteristics of fuel assemblies for reactor physics applications, which has been enhanced to perform criticality safety calculations. Throughout the years, CRISTAL, starting with APOLLO1 and MORET 3 (a 3D Monte Carlo code), has been improved to account for the growth of its qualification database and for increasing user requirements. Today, CRISTAL V0 is an up-to-date computational tool incorporating a modern basic microscopic cross section set based on JEF2.2 and the comprehensive APOLLO2 and MORET 4 codes. APOLLO2 is well suited for criticality standards calculations as it includes a sophisticated self shielding approach, a P{sub ij} flux determination, and a 1D transport (S{sub n}) process. CRISTAL V0 is the result of more than five years of development work focusing on theoretical approaches and the implementation of user-friendly graphical interfaces. Due to its comprehensive physical simulation and thanks to its broad qualification database with more than a thousand benchmark/calculation comparisons, CRISTAL V0 provides outstanding and reliable accuracy for criticality evaluations for configurations covering the entire fuel cycle (i.e. from enrichment, pellet/assembly fabrication, transportation, to fuel reprocessing). After a brief description of the calculation scheme and the physics algorithms used in this code package, results for the various fissile media encountered in a UO{sub 2} fuel fabrication plant will be detailed and discussed. (authors)« less

Tuner control system of Spoke012 SRF cavity for C-ADS injector I

NASA Astrophysics Data System (ADS)

Liu, Na; Sun, Yi; Wang, Guang-Wei; Mi, Zheng-Hui; Lin, Hai-Ying; Wang, Qun-Yao; Liu, Rong; Ma, Xin-Peng

2016-09-01

A new tuner control system for spoke superconducting radio frequency (SRF) cavities has been developed and applied to cryomodule I of the C-ADS injector I at the Institute of High Energy Physics, Chinese Academy of Sciences. We have successfully implemented the tuner controller based on Programmable Logic Controller (PLC) for the first time and achieved a cavity tuning phase error of ±0.7° (about ±4 Hz peak to peak) in the presence of electromechanical coupled resonance. This paper presents preliminary experimental results based on the PLC tuner controller under proton beam commissioning. Supported by Proton linac accelerator I of China Accelerator Driven sub-critical System (Y12C32W129)

Study of 232Th(n, γ) and 232Th(n,f) reaction rates in a graphite moderated spallation neutron field produced by 1.6 GeV deuterons on lead target

NASA Astrophysics Data System (ADS)

Asquith, N. L.; Hashemi-Nezhad, S. R.; Westmeier, W.; Zhuk, I.; Tyutyunnikov, S.; Adam, J.

2015-02-01

The Gamma-3 assembly of the Joint Institute for Nuclear Research (JINR), Dubna, Russia is designed to emulate the neutron spectrum of a thermal Accelerator Driven System (ADS). It consists of a lead spallation target surrounded by reactor grade graphite. The target was irradiated with 1.6 GeV deuterons from the Nuclotron accelerator and the neutron capture and fission rate of 232Th in several locations within the assembly were experimentally measured. 232Th is a proposed fuel for envisaged Accelerator Driven Systems and these two reactions are fundamental to the performance and feasibility of 232Th in an ADS. The irradiation of the Gamma-3 assembly was also simulated using MCNPX 2.7 with the INCL4 intra-nuclear cascade and ABLA fission/evaporation models. Good agreement between the experimentally measured and calculated reaction rates was found. This serves as a good validation for the computational models and cross section data used to simulate neutron production and transport of spallation neutrons within a thermal ADS.

Rayleigh-Taylor and Richtmyer-Meshkov Instabilities in Turbulent Regime

NASA Astrophysics Data System (ADS)

Dimonte, G.

1998-11-01

The Rayleigh-Taylor instability (RTI) and its shock driven analog, the Richtmyer-Meshkov instability (RMI), affect a wide variety of important phenomena from sub-terrainian to astrophysical environments. The ``fluids" are equally varied from plasmas and magnetic fields to elastic-plastic solids. In most applications, the instabilities occur with a complex acceleration history and evolve to a highly nonlinear state, making the theoretical description formidable. We will link the fluid and plasma regimes while describing the theoretical issues and basic experiments in different venues to isolate key physics issues. RMI experiments on the Nova laser investigate the affects of compressibility with strong radiatively driven shocks (Mach > 10) in near solid density plasmas of sub-millimeter scale. The growth of single sinusoidal and random 3-D perturbations are measured using backlit radiography. RTI experiments with the Linear Electric Motor (LEM) are conducted with a variety of acceleration (<< 10^4 m/s^2) histories and fluids of 10 cm scale. Turbulent RTI experiments with high Reynolds number liquids show self-similar growth which is characterized with laser induced fluorescence. LEM experiments with an elastic-plastic material (yogurt) exhibit a critical wavelength and amplitude for instability. The experimental results will be compared with linear and nonlinear theories and hydrodynamic simulations.

Development of High-Gradient Dielectric Laser-Driven Particle Accelerator Structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Byer, Robert L.

2013-11-07

The thrust of Stanford's program is to conduct research on high-gradient dielectric accelerator structures driven with high repetition-rate, tabletop infrared lasers. The close collaboration between Stanford and SLAC (Stanford Linear Accelerator Center) is critical to the success of this project, because it provides a unique environment where prototype dielectric accelerator structures can be rapidly fabricated and tested with a relativistic electron beam.

Accelerator Reactor Coupling for Energy Production in Advanced Nuclear Fuel Cycles

DOE PAGES

Brown, Nicholas R.; Heidet, Florent; Haj Tahar, Malek

2016-01-01

This article is a review of several accelerator–reactor interface issues and nuclear fuel cycle applications of acceleratordriven subcritical systems. The systems considered here have the primary goal of energy production, but that goal is accomplished via a specific application in various proposed nuclear fuel cycles, such as breed-and-burn of fertile material or burning of transuranic material. Several basic principles are reviewed, starting from the proton beam window including the target, blanket, reactor core, and up to the fuel cycle. We focus on issues of interest, such as the impact of the energy required to run the accelerator and associated systemsmore » on the potential electricity delivered to the grid. Accelerator-driven systems feature many of the constraints and issues associated with critical reactors, with the added challenges of subcritical operation and coupling to an accelerator. Reliable accelerator operation and avoidance of beam trips are critically important. One interesting challenge is measurement of blanket subcriticality level during operation. We also review the potential benefits of accelerator-driven systems in various nuclear fuel cycle applications. Ultimately, accelerator-driven subcritical systems with the goal of transmutation of transuranic material have lower 100,000-year radioactivity than a critical fast reactor with recycling of uranium and plutonium.« less

A laboratory facility for research on wind-driven rain intrusion in building envelope assemblies

Treesearch

Samuel V. Glass

2010-01-01

Moisture management is critical for durable, energy-efficient buildings. To address the need for research on wind-driven rain intrusion in wall assemblies, the U.S. Forest Products Laboratory is developing a new facility. This paper describes the underlying principle of this facility and its capabilities.

Impact of intermediate and high energy nuclear data on the neutronic safety parameters of MYRRHA accelerator driven system

NASA Astrophysics Data System (ADS)

Stankovskiy, Alexey; Çelik, Yurdunaz; Eynde, Gert Van den

2017-09-01

Perturbation of external neutron source can cause significant local power changes transformed into undesired safety-related events in an accelerator driven system. Therefore for the accurate design of MYRRHA sub-critical core it is important to evaluate the uncertainty of power responses caused by the uncertainties in nuclear reaction models describing the particle transport from primary proton energy down to the evaluated nuclear data table range. The calculations with a set of models resulted in quite low uncertainty on the local power caused by significant perturbation of primary neutron yield from proton interactions with lead and bismuth isotopes. The considered accidental event of prescribed proton beam shape loss causes drastic increase in local power but does not practically change the total core thermal power making this effect difficult to detect. In the same time the results demonstrate a correlation between perturbed local power responses in normal operation and misaligned beam conditions indicating that generation of covariance data for proton and neutron induced neutron multiplicities for lead and bismuth isotopes is needed to obtain reliable uncertainties for local power responses.

Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

NASA Astrophysics Data System (ADS)

Sajo-Bohus, Laszlo; Greaves, Eduardo D.; Davila, Jesus; Barros, Haydn; Pino, Felix; Barrera, Maria T.; Farina, Fulvio

2015-07-01

During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e'n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides 232Th, 238U and 237Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program.

Rayleigh-Taylor mixing with space-dependent acceleration

NASA Astrophysics Data System (ADS)

Abarzhi, Snezhana

2016-11-01

We extend the momentum model to describe Rayleigh-Taylor (RT) mixing driven by a space-dependent acceleration. The acceleration is a power-law function of space coordinate, similarly to astrophysical and plasma fusion applications. In RT flow the dynamics of a fluid parcel is driven by a balance per unit mass of the rates of momentum gain and loss. We find analytical solutions in the cases of balanced and imbalanced gains and losses, and identify their dependence on the acceleration exponent. The existence is shown of two typical sub-regimes of self-similar RT mixing - the acceleration-driven Rayleigh-Taylor-type mixing and dissipation-driven Richtymer-Meshkov-type mixing with the latter being in general non-universal. Possible scenarios are proposed for transitions from the balanced dynamics to the imbalanced self-similar dynamics. Scaling and correlations properties of RT mixing are studied on the basis of dimensional analysis. Departures are outlined of RT dynamics with space-dependent acceleration from canonical cases of homogeneous turbulence as well as blast waves with first and second kind self-similarity. The work is supported by the US National Science Foundation.

Laser-driven ion acceleration: methods, challenges and prospects

NASA Astrophysics Data System (ADS)

Badziak, J.

2018-01-01

The recent development of laser technology has resulted in the construction of short-pulse lasers capable of generating fs light pulses with PW powers and intensities exceeding 1021 W/cm2, and has laid the basis for the multi-PW lasers, just being built in Europe, that will produce fs pulses of ultra-relativistic intensities ~ 1023 - 1024 W/cm2. The interaction of such an intense laser pulse with a dense target can result in the generation of collimated beams of ions of multi-MeV to GeV energies of sub-ps time durations and of extremely high beam intensities and ion fluencies, barely attainable with conventional RF-driven accelerators. Ion beams with such unique features have the potential for application in various fields of scientific research as well as in medical and technological developments. This paper provides a brief review of state-of-the art in laser-driven ion acceleration, with a focus on basic ion acceleration mechanisms and the production of ultra-intense ion beams. The challenges facing laser-driven ion acceleration studies, in particular those connected with potential applications of laser-accelerated ion beams, are also discussed.

Enhanced Laser-Driven Ion Acceleration by Superponderomotive Electrons Generated from Near-Critical-Density Plasma

NASA Astrophysics Data System (ADS)

Bin, J. H.; Yeung, M.; Gong, Z.; Wang, H. Y.; Kreuzer, C.; Zhou, M. L.; Streeter, M. J. V.; Foster, P. S.; Cousens, S.; Dromey, B.; Meyer-ter-Vehn, J.; Zepf, M.; Schreiber, J.

2018-02-01

We report on the experimental studies of laser driven ion acceleration from a double-layer target where a near-critical density target with a few-micron thickness is coated in front of a nanometer-thin diamondlike carbon foil. A significant enhancement of proton maximum energies from 12 to ˜30 MeV is observed when a relativistic laser pulse impinges on the double-layer target under linear polarization. We attributed the enhanced acceleration to superponderomotive electrons that were simultaneously measured in the experiments with energies far beyond the free-electron ponderomotive limit. Our interpretation is supported by two-dimensional simulation results.

Component Selection, Accelerated Testing, and Improved Modeling of AMTEC Systems for Space Power (abstract)

NASA Technical Reports Server (NTRS)

Williams, R. M.; Jeffries-Nakamura, B.; Ryan, M. A.; Underwood, M. L.; Suitor, J.; O'Connor, D.

1993-01-01

Alkali metal thermal to electric converter (AMTEC) designs for space power are numerous, but selection of materials for construction of long-lived AMTEC devices has been limited to electrodes, current collectors, and the solid electrolyte. AMTEC devices with lifetimes greater than 5 years require careful selection and life testing of all hot-side components. The likely selection of a remote condensed design for initial flight test and probable use with a GPHS in AMTEC powered outer planet probes requires the device to be constructed to tolerate T greater than 1150K, as well as exposure to Na(sub (g)), and Na(sub (liq)) on the high pressure side. The temperatures involved make critical high strength and chemical resistance to Na containing Na(sub 2)O. Selection among materials which can be worked should not be driven by ease of fabricability, as high temperature stability is the critical issue. These concepts drive the selection of Mo alloys for Na(sub (liq)) containment in AMTEC cells for T to 1150K operation, as they are significantly stronger than comparable NB or Ta alloys, are less soluble in Na(sub (liq)) containing dissolved Na(sub 2)O, are workable compared to W alloys (which might be used for certain components), and are ductile at the T greater than 500K of proposed AMTEC modules in space applications.

Advances in Nonlinear Non-Scaling FFAGs

NASA Astrophysics Data System (ADS)

Johnstone, C.; Berz, M.; Makino, K.; Koscielniak, S.; Snopok, P.

Accelerators are playing increasingly important roles in basic science, technology, and medicine. Ultra high-intensity and high-energy (GeV) proton drivers are a critical technology for accelerator-driven sub-critical reactors (ADS) and many HEP programs (Muon Collider) but remain particularly challenging, encountering duty cycle and space-charge limits in the synchrotron and machine size concerns in the weaker-focusing cyclotrons; a 10-20 MW proton driver is not presently considered technically achievable with conventional re-circulating accelerators. One, as-yet, unexplored re-circulating accelerator, the Fixed-field Alternating Gradient or FFAG, is an attractive alternative to the other approaches to a high-power beam source. Its strong focusing optics can mitigate space charge effects and achieve higher bunch charges than are possible in a cyclotron, and a recent innovation in design has coupled stable tunes with isochronous orbits, making the FFAG capable of fixed-frequency, CW acceleration, as in the classical cyclotron but beyond their energy reach, well into the relativistic regime. This new concept has been advanced in non-scaling nonlinear FFAGs using powerful new methodologies developed for FFAG accelerator design and simulation. The machine described here has the high average current advantage and duty cycle of the cyclotron (without using broadband RF frequencies) in combination with the strong focusing, smaller losses, and energy variability that are more typical of the synchrotron. The current industrial and medical standard is a cyclotron, but a competing CW FFAG could promote a shift in this baseline. This paper reports on these new advances in FFAG accelerator technology and presents advanced modeling tools for fixed-field accelerators unique to the code COSY INFINITY.1

Sulfate-bicarbonate exchange in brush-border membranes from rat renal cortex

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pritchard, J.B.

1987-02-01

Under Na/sup +/-free conditions /sup 35/SO/sub 4//sup 2 -/ uptake by rat renal brush-border membrane (BBM) vesicles could be driven by imposition of a HCO/sup -//sub 3/ gradient (in greater than out). The initial rate of /sup 35/SO/sub 4//sup 2 -/ uptake was stimulated 10-fold, and peak overshoot exceeded equilibrium uptake by 2-3 times. Cl/sup -/, SCN/sup -/, NO/sub 3//sup -/, I/sup -/, and OH/sup -/ were able to substitute for HCO/sub 3//sup -/. Divalent anions, including /sup 35/SO/sub 4//sup 2 -/ itself, were less effective as counterions. HCO/sub 3//sup -/-SO/sub 4//sup 2 -/ exchange was cis-inhibited by disulfonic stilbenes,more » ((SITS)(DIDS)), phloretin, Hg, and S/sub 2/O/sub 3//sup 2 -/. HCO/sub 3//sup -/-driven /sup 35/SO/sub 4//sup 2 -/ uptake was saturable, with an apparent K/sub m/ of 0.4 mM for SO/sub 4//sup 2 -/. Simultaneous imposition of Na/sup +/ and HCO/sub 3//sup -/ gradients produced approximately additive stimulation of /sup 35/SO/sub 4//sup 2 -/ uptake. The HCO/sub 3//sup -/-driven component of /sup 35/SO/sub 4//sup 2 -/ uptake, but not the component driven by Na/sup +/, was inhibited by SITS. Finally, Na/sup +/-driven SO/sub 4//sup 2 -/ accumulation could be reduced by imposing an out greater than in HCO/sub 3//sup +/ gradient, conditions accelerating exchange driven SO/sub 4//sup 2 -/ efflux. These findings indicate the presence of separate Na/sup +/-SO/sub 4//sup 2 -/ cotransport and SO /sub 4//sup 2 -/-anion exchange pathways in the same BBM vesicles.« less

Advanced electrical current measurements of microdischarges: evidence of sub-critical pulses and ion currents in barrier discharge in air

NASA Astrophysics Data System (ADS)

Synek, Petr; Zemánek, Miroslav; Kudrle, Vít; Hoder, Tomáš

2018-04-01

Electrical current measurements in corona or barrier microdischarges are a challenge as they require both high temporal resolution and a large dynamic range of the current probe used. In this article, we apply a simple self-assembled current probe and compare it to commercial ones. An analysis in the time and frequency domain is carried out. Moreover, an improved methodology is presented, enabling both temporal resolution in sub-nanosecond times and current sensitivity in the order of tens of micro-amperes. Combining this methodology with a high-tech oscilloscope and self-developed software, a unique statistical analysis of currents in volume barrier discharge driven in atmospheric-pressure air is made for over 80 consecutive periods of a 15 kHz applied voltage. We reveal the presence of repetitive sub-critical current pulses and conclude that these can be identified with the discharging of surface charge microdomains. Moreover, extremely low, long-lasting microsecond currents were detected which are caused by ion flow, and are analysed in detail. The statistical behaviour presented gives deeper insight into the discharge physics of these usually undetectable current signals.

Generation of quasi-monoenergetic heavy ion beams via staged shock wave acceleration driven by intense laser pulses in near-critical plasmas

NASA Astrophysics Data System (ADS)

Zhang, W. L.; Qiao, B.; Shen, X. F.; You, W. Y.; Huang, T. W.; Yan, X. Q.; Wu, S. Z.; Zhou, C. T.; He, X. T.

2016-09-01

Laser-driven ion acceleration potentially offers a compact, cost-effective alternative to conventional accelerators for scientific, technological, and health-care applications. A novel scheme for heavy ion acceleration in near-critical plasmas via staged shock waves driven by intense laser pulses is proposed, where, in front of the heavy ion target, a light ion layer is used for launching a high-speed electrostatic shock wave. This shock is enhanced at the interface before it is transmitted into the heavy ion plasmas. Monoenergetic heavy ion beam with much higher energy can be generated by the transmitted shock, comparing to the shock wave acceleration in pure heavy ion target. Two-dimensional particle-in-cell simulations show that quasi-monoenergetic {{{C}}}6+ ion beams with peak energy 168 MeV and considerable particle number 2.1 × {10}11 are obtained by laser pulses at intensity of 1.66 × {10}20 {{W}} {{cm}}-2 in such staged shock wave acceleration scheme. Similarly a high-quality {{Al}}10+ ion beam with a well-defined peak with energy 250 MeV and spread δ E/{E}0=30 % can also be obtained in this scheme.

Cavity Preparation/assembly Techniques and Impact on Q, Realistic Q - Factors in a Module, Review of Modules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peter Kneisel

2005-03-19

This contribution summarizes the surface preparation procedures for niobium cavities presently used both in laboratory experiments and for modules, such as buffered chemical polishing (BCP), electropolishing (EP), high pressure ultrapure water rinsing (HPR), CO{sub 2} snow cleaning and high temperature heat treatments for hydrogen degassing or postpurification. The impact of surface treatments and the degree of cleanliness during assembly procedures on cavity performance (Q - value and accelerating gradient E{sub acc}) will be discussed. In addition, an attempt will be made to summarize the experiences made in module assemblies in different labs/projects such as DESY(TTF), Jlab (Upgrade) and SNS.

THE HOT CRITICAL ASSEMBLY $sub 4$CESAR$sub 4$ (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanguy, P.

1963-07-01

With Cesar, the Cadarache Center for Nuclear Studies will be equipped with a zero-power critical assembly, which will enable it to obtain the data necessary for the development of natural uranium, graphite, gas reactors. Reactivity balance, evolution of the reactivity, and deformation of the flux curves are to be studied. These studies will complement those already being done on Marius, but carried out at room temperature; in Cesar the graphite temperature can reach 500 deg C. (auth)

Corrosion fatigue crack growth behavior of titanium alloys in aqueous solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shipilov, S.A.

1998-01-01

The corrosion fatigue crack growth (FCG) behavior, the effect of applied potential on corrosion FCG rates, and the fracture surfaces of VT20 (near-{alpha}) and TS6 (near-{beta}) titanium alloys were studied. Environments were aqueous solutions of sodium chloride (NaCl), sodium hydroxide (NaOH), potassium hydroxide (KOH), ferric chloride (FeCl{sub 3}), and chromic acid (H{sub 2}CrO{sub 4}) with and without NaCl. Depending upon solution composition, corrosion FCG rates were found to be higher or lower than those in air. Cathodic polarization retarded the corrosion FCG, while anodic polarization accelerated insignificantly or almost did not influence it in most of the solutions investigated. However,more » cathodic polarization accelerated corrosion FCG in 0.6 M FeCl{sub 3} and 0.5 M to 2 M H{sub 2}CrO{sub 4} + 0.01 M to 0.1 M NaCl solutions by a dozen times when the maximum stress intensity (K{sub max}) exceeded certain critical values. When K{sub max} was lower than the critical values, the same cathodic polarization (with all other /conditions being equal) retarded corrosion FCG. Results suggested the accelerated crack growth at cathodic potentials resulted from hydrogen-induced cracking (HIC). Therefore, critical values of K{sub max}, as well as the stress intensity range ({Delta}K) were regarded as corresponding to the beginning of corrosion FCG according to a HIC mechanism and designated as K{sub HIC} and {Delta}K{sub HIC}.« less

Real-Time Phase Correction Based on FPGA in the Beam Position and Phase Measurement System

NASA Astrophysics Data System (ADS)

Gao, Xingshun; Zhao, Lei; Liu, Jinxin; Jiang, Zouyi; Hu, Xiaofang; Liu, Shubin; An, Qi

2016-12-01

A fully digital beam position and phase measurement (BPPM) system was designed for the linear accelerator (LINAC) in Accelerator Driven Sub-critical System (ADS) in China. Phase information is obtained from the summed signals from four pick-ups of the Beam Position Monitor (BPM). Considering that the delay variations of different analog circuit channels would introduce phase measurement errors, we propose a new method to tune the digital waveforms of four channels before summation and achieve real-time error correction. The process is based on the vector rotation method and implemented within one single Field Programmable Gate Array (FPGA) device. Tests were conducted to evaluate this correction method and the results indicate that a phase correction precision better than ± 0.3° over the dynamic range from -60 dBm to 0 dBm is achieved.

Fuel assembly design for APR1400 with low CBC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hah, Chang Joo, E-mail: changhah@kings.ac.kr

2015-04-29

APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gdmore » rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to Δk{sub TARGET}. A set of new designed fuel assembly satisfies an objective function, min [f=∑{sub i}(Δk{sub FA}−Δk{sub i})], and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to Δk{sub TARGET} as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.« less

First Observations of Laser-Driven Acceleration of Relativistic Electrons in a Semi-Infinite Vacuum Space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Plettner, T.; Byer, R.L.; Smith, T.I.

2006-02-17

We have observed acceleration of relativistic electrons in vacuum driven by a linearly polarized visible laser beam incident on a thin gold-coated reflective boundary. The observed energy modulation effect follows all the characteristics expected for linear acceleration caused by a longitudinal electric field. As predicted by the Lawson-Woodward theorem the laser driven modulation only appears in the presence of the boundary. It shows a linear dependence with the strength of the electric field of the laser beam and also it is critically dependent on the laser polarization. Finally, it appears to follow the expected angular dependence of the inverse transitionmore » radiation process. experiment as the Laser Electron Accelerator Project (LEAP).« less

Neutron Detector Signal Processing to Calculate the Effective Neutron Multiplication Factor of Subcritical Assemblies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talamo, Alberto; Gohar, Yousry

2016-06-01

This report describes different methodologies to calculate the effective neutron multiplication factor of subcritical assemblies by processing the neutron detector signals using MATLAB scripts. The subcritical assembly can be driven either by a spontaneous fission neutron source (e.g. californium) or by a neutron source generated from the interactions of accelerated particles with target materials. In the latter case, when the particle accelerator operates in a pulsed mode, the signals are typically stored into two files. One file contains the time when neutron reactions occur and the other contains the times when the neutron pulses start. In both files, the timemore » is given by an integer representing the number of time bins since the start of the counting. These signal files are used to construct the neutron count distribution from a single neutron pulse. The built-in functions of MATLAB are used to calculate the effective neutron multiplication factor through the application of the prompt decay fitting or the area method to the neutron count distribution. If the subcritical assembly is driven by a spontaneous fission neutron source, then the effective multiplication factor can be evaluated either using the prompt neutron decay constant obtained from Rossi or Feynman distributions or the Modified Source Multiplication (MSM) method.« less

Small Ground-Level Enhancement of 6 January 2014: Acceleration by CME-Driven Shock?

NASA Astrophysics Data System (ADS)

Li, C.; Miroshnichenko, L. I.; Sdobnov, V. E.

2016-03-01

Available spectral data for solar energetic particles (SEPs) measured near the Earth's orbit (GOES-13) and on the terrestrial surface (polar neutron monitors) on 6 January 2014 are analyzed. A feature of this solar proton event (SPE) and weak ground-level enhancement (GLE) is that the source was located behind the limb. For the purpose of comparison, we also use the Advanced Composition Explorer (ACE) data on sub-relativistic electrons and GOES-13 measurements of a strong and extended proton event on 8 - 9 January 2014. It was found that the surface observations at energies {>} 433 MeV and GOES-13 data at {>} 30 - {>} 700 MeV may be satisfactorily reconciled by a power-law time-of-maximum (TOM) spectrum with a characteristic exponential tail (cutoff). Some methodological difficulties of spectrum determination are discussed. Assuming that the TOM spectrum near the Earth is a proxy of the spectrum of accelerated particles in the source, we critically consider the possibility of shock acceleration to relativistic energies in the solar corona. Finally, it is suggested to interpret the observational features of this GLE under the assumption that small GLEs may be produced by shocks driven by coronal mass ejections. However, the serious limitations of such an approach to the problem of the SCR spectrum prevent drawing firm conclusions in this controversial field.

Reactive oxygen species promote heat shock protein 90-mediated HBV capsid assembly

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Yoon Sik, E-mail: yumshak@naver.com; Seo, Hyun Wook, E-mail: suruk@naver.com; Jung, Guhung, E-mail: drjung@snu.ac.kr

2015-02-13

Hepatitis B virus (HBV) infection induces reactive oxygen species (ROS) production and has been associated with the development of hepatocellular carcinoma (HCC). ROS are also an important factor in HCC because the accumulated ROS leads to abnormal cell proliferation and chromosome mutation. In oxidative stress, heat shock protein 90 (Hsp90) and glutathione (GSH) function as part of the defense mechanism. Hsp90 prevents cellular component from oxidative stress, and GSH acts as antioxidants scavenging ROS in the cell. However, it is not known whether molecules regulated by oxidative stress are involved in HBV capsid assembly. Based on the previous study thatmore » Hsp90 facilitates HBV capsid assembly, which is an important step for the packing of viral particles, here, we show that ROS enrich Hsp90-driven HBV capsid formation. In cell-free system, HBV capsid assembly was facilitated by ROS with Hsp90, whereas it was decreased without Hsp90. In addition, GSH inhibited the function of Hsp90 to decrease HBV capsid assembly. Consistent with the result of cell-free system, ROS and buthionine sulfoximine (BS), an inhibitor of GSH synthesis, increased HBV capsid formation in HepG2.2.15 cells. Thus, our study uncovers the interplay between ROS and Hsp90 during HBV capsid assembly. - Highlights: • We examined H{sub 2}O{sub 2} and GSH modulate HBV capsid assembly. • H{sub 2}O{sub 2} facilitates HBV capsid assembly in the presence of Hsp90. • GSH inhibits function of Hsp90 in facilitating HBV capsid assembly. • H{sub 2}O{sub 2} and GSH induce conformation change of Hsp90.« less

Physical phenomena and the microgravity response

NASA Technical Reports Server (NTRS)

Todd, Paul

1989-01-01

The living biological cell is not a sack of Newtonian fluid containing systems of chemical reactions at equilibrium. It is a kinetically driven system, not a thermodynamically driven system. While the cell as a whole might be considered isothermal, at the scale of individual macromolecular events there is heat generated, and presumably sharp thermal gradients exist at the submicron level. Basic physical phenomena to be considered when exploring the cell's response to inertial acceleration include particle sedimentation, solutal convection, motility electrokinetics, cytoskeletal work, and hydrostatic pressure. Protein crystal growth experiments, for example, illustrate the profound effects of convection currents on macromolecular assembly. Reaction kinetics in the cell vary all the way from diffusion-limited to life-time limited. Transport processes vary from free diffusion, to facilitated and active transmembrane transport, to contractile-protein-driven motility, to crystalline immobilization. At least four physical states of matter exist in the cell: aqueous, non-aqueous, immiscible-aqueous, and solid. Levels of order vary from crystalline to free solution. The relative volumes of these states profoundly influence the cell's response to inertial acceleration. Such subcellular phenomena as stretch-receptor activation, microtubule re-assembly, synaptic junction formation, chemotactic receptor activation, and statolith sedimentation were studied recently with respect to both their basic mechanisms and their responsiveness to inertial acceleration. From such studies a widespread role of cytoskeletal organization is becoming apparent.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Emanuela Barzi et al.

Fermilab is developing 11 T superconducting dipole magnets for future accelerators based on Nb{sub 3}Sn conductor. Within the High Field Magnet Project, the first prototypes feature 1 meter long two-layer shell-type coils and common coils. For the former, keystoned Rutherford-type cable made of 28 Nb{sub 3}Sn strands 1 mm in diameter are used, whereas for the latter a 60-strand flat cable was chosen. Multifilamentary Nb{sub 3}Sn strands produced with various technologies by industry were used for the development and testing of the prototype cable. An experimental cabling machine with up to 28-strand capacity that has been recently purchased, installed andmore » commissioned at Fermilab, has allowed further advances in strand and cable studies. Cables of 27 and 28 strands of various structures (single strands or assemblies of sub-strands), with aspect ratios from 7 to 17, packing factors from 85 to 95%, with and without a stainless steel core were made out of Copper, NbTi, and Modified Jelly Roll (OST), Powder-in-Tube (SMI) and Internal Tin (Mitsubishi) Nb{sub 3}Sn strands. optimal parameters were determined with respect to mechanical and electrical properties, including critical current degradation, interstrand resistance, etc. Round strands of the same billets used in the cables were deformed by rolling them down to various thicknesses. Their critical current Ic was then measured and compared with that of the strands extracted from cables having different packing factors. This paper summarizes the results of such R and D efforts at Fermilab.« less

Summary Report of Mission Acceleration Measurements for STS-78. Launched June 20, 1996

NASA Technical Reports Server (NTRS)

Hakimzadeh, Roshanak; Hrovat, Kenneth; McPherson, Kevin M.; Moskowitz, Milton E.; Rogers, Melissa J. B.

1997-01-01

The microgravity environment of the Space Shuttle Columbia was measured during the STS-78 mission using accelerometers from three different instruments: the Orbital Acceleration Research Experiment, the Space Acceleration Measurement System and the Microgravity Measurement Assembly. The quasi-steady environment was also calculated in near real-time during the mission by the Microgravity Analysis Workstation. The Orbital Acceleration Research Experiment provided investigators with real-time quasi-steady acceleration measurements. The Space Acceleration Measurement System recorded higher frequency data on-board for post-mission analysis. The Microgravity Measurement Assembly provided investigators with real-time quasi-steady and higher frequency acceleration measurements. The Microgravity Analysis Workstation provided calculation of the quasi-steady environment. This calculation was presented to the science teams in real-time during the mission. The microgravity environment related to several different Orbiter, crew and experiment operations is presented and interpreted in this report. A radiator deploy, the Flight Control System checkout, and a vernier reaction control system reboost demonstration had minimal effects on the acceleration environment, with excitation of frequencies in the 0.01 to 10 Hz range. Flash Evaporator System venting had no noticeable effect on the environment while supply and waste water dumps caused excursions of 2 x lO(exp -6) to 4 x 10(exp -6) g in the Y(sub b) and Z(sub b) directions. Crew sleep and ergometer exercise periods can be clearly seen in the acceleration data, as expected. Accelerations related to the two Life Science Laboratory Equipment Refrigerator/Freezers were apparent in the data as are accelerations caused by the Johnson Space Center Projects Centrifuge. As on previous microgravity missions, several signals are present in the acceleration data for which a source has not been identified. The causes of these accelerations are under investigation.

An Assessment of the Detection of Highly Enriched Uranium and its Use in an Improvised Nuclear Device using the Monte Carlo Computer Code MCNP-5

NASA Astrophysics Data System (ADS)

Cochran, Thomas

2007-04-01

In 2002 and again in 2003, an investigative journalist unit at ABC News transported a 6.8 kilogram metallic slug of depleted uranium (DU) via shipping container from Istanbul, Turkey to Brooklyn, NY and from Jakarta, Indonesia to Long Beach, CA. Targeted inspection of these shipping containers by Department of Homeland Security (DHS) personnel, included the use of gamma-ray imaging, portal monitors and hand-held radiation detectors, did not uncover the hidden DU. Monte Carlo analysis of the gamma-ray intensity and spectrum of a DU slug and one consisting of highly-enriched uranium (HEU) showed that DU was a proper surrogate for testing the ability of DHS to detect the illicit transport of HEU. Our analysis using MCNP-5 illustrated the ease of fully shielding an HEU sample to avoid detection. The assembly of an Improvised Nuclear Device (IND) -- a crude atomic bomb -- from sub-critical pieces of HEU metal was then examined via Monte Carlo criticality calculations. Nuclear explosive yields of such an IND as a function of the speed of assembly of the sub-critical HEU components were derived. A comparison was made between the more rapid assembly of sub-critical pieces of HEU in the ``Little Boy'' (Hiroshima) weapon's gun barrel and gravity assembly (i.e., dropping one sub-critical piece of HEU on another from a specified height). Based on the difficulty of detection of HEU and the straightforward construction of an IND utilizing HEU, current U.S. government policy must be modified to more urgently prioritize elimination of and securing the global inventories of HEU.

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Ban, G.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate on-line reactivity monitoring and subcriticality level determination in Accelerator Driven Systems. Therefore the VENUS reactor at SCK.CEN in Mol (Belgium) was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of the on-linemore » subcriticality monitoring methodology. Moreover a benchmarking tool is required for nuclear data research and code validation. In this paper the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the rod drop technique and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Kochetkov, A.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate online reactivity monitoring and subcriticality level determination in accelerator driven systems (ADS). Therefore, the VENUS reactor at SCK.CEN in Mol, Belgium, was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS. The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of themore » online subcriticality monitoring methodology. Moreover, a benchmarking tool is required for nuclear data research and code validation. In this paper, the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the positive period method and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

IAEA activities in the area of partitioning and transmutation

NASA Astrophysics Data System (ADS)

Stanculescu, Alexander

2006-06-01

Four major challenges are facing the long-term development of nuclear energy: improvement of the economic competitiveness, meeting increasingly stringent safety requirements, adhering to the criteria of sustainable development, and public acceptance. Meeting the sustainability criteria is the driving force behind the topic of this paper. In this context, sustainability has two aspects: natural resources and waste management. IAEA's activities in the area of Partitioning and Transmutation (P&T) are mostly in response to the latter. While not involving the large quantities of gaseous products and toxic solid wastes associated with fossil fuels, radioactive waste disposal is today's dominant public acceptance issue. In fact, small waste quantities permit a rigorous confinement strategy, and mined geological disposal is the strategy followed by some countries. Nevertheless, political opposition arguing that this does not yet constitute a safe disposal technology has largely stalled these efforts. One of the primary reasons cited is the long life of many of the radioisotopes generated from fission. This concern has led to increased R&D efforts to develop a technology aimed at reducing the amount and radio-toxicity of long-lived radioactive waste through transmutation in fission reactors or sub-critical systems. In the frame of the Project on Technology Advances in Fast Reactors and Accelerator-Driven Systems (ADS), the IAEA initiated a number of activities on utilization of plutonium and transmutation of long-lived radioactive waste, ADS, and deuterium-tritium plasma-driven sub-critical systems. The paper presents past accomplishments, current status and planned activities of this IAEA project.

Quasi-monoenergetic laser-plasma acceleration of electrons to 2 GeV

PubMed Central

Wang, Xiaoming; Zgadzaj, Rafal; Fazel, Neil; Li, Zhengyan; Yi, S. A.; Zhang, Xi; Henderson, Watson; Chang, Y.-Y.; Korzekwa, R.; Tsai, H.-E.; Pai, C.-H.; Quevedo, H.; Dyer, G.; Gaul, E.; Martinez, M.; Bernstein, A. C.; Borger, T.; Spinks, M.; Donovan, M.; Khudik, V.; Shvets, G.; Ditmire, T.; Downer, M. C.

2013-01-01

Laser-plasma accelerators of only a centimetre’s length have produced nearly monoenergetic electron bunches with energy as high as 1 GeV. Scaling these compact accelerators to multi-gigaelectronvolt energy would open the prospect of building X-ray free-electron lasers and linear colliders hundreds of times smaller than conventional facilities, but the 1 GeV barrier has so far proven insurmountable. Here, by applying new petawatt laser technology, we produce electron bunches with a spectrum prominently peaked at 2 GeV with only a few per cent energy spread and unprecedented sub-milliradian divergence. Petawatt pulses inject ambient plasma electrons into the laser-driven accelerator at much lower density than was previously possible, thereby overcoming the principal physical barriers to multi-gigaelectronvolt acceleration: dephasing between laser-driven wake and accelerating electrons and laser pulse erosion. Simulations indicate that with improvements in the laser-pulse focus quality, acceleration to nearly 10 GeV should be possible with the available pulse energy. PMID:23756359

Analysis of benchmark critical experiments with ENDF/B-VI data sets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hardy, J. Jr.; Kahler, A.C.

1991-12-31

Several clean critical experiments were analyzed with ENDF/B-VI data to assess the adequacy of the data for U{sup 235}, U{sup 238} and oxygen. These experiments were (1) a set of homogeneous U{sup 235}-H{sub 2}O assemblies spanning a wide range of hydrogen/uranium ratio, and (2) TRX-1, a simple, H{sub 2}O-moderated Bettis lattice of slightly-enriched uranium metal rods. The analyses used the Monte Carlo program RCP01, with explicit three-dimensional geometry and detailed representation of cross sections. For the homogeneous criticals, calculated k{sub crit} values for large, thermal assemblies show good agreement with experiment. This supports the evaluated thermal criticality parameters for U{supmore » 235}. However, for assemblies with smaller H/U ratios, k{sub crit} values increase significantly with increasing leakage and flux-spectrum hardness. These trends suggest that leakage is underpredicted and that the resonance eta of the ENDF/B-VI U{sup 235} is too large. For TRX-1, reasonably good agreement is found with measured lattice parameters (reaction-rate ratios). Of primary interest is rho28, the ratio of above-thermal to thermal U{sup 238} capture. Calculated rho28 is 2.3 ({+-} 1.7) % above measurement, suggesting that U{sup 238} resonance capture remains slightly overpredicted with ENDF/B-VI. However, agreement is better than observed with earlier versions of ENDF/B.« less

Concentration-Driven Assembly and Sol–Gel Transition of π-Conjugated Oligopeptides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Yuecheng; Li, Bo; Li, Songsong

Advances in supramolecular assembly have enabled the design and synthesis of functional materials with well-defined structures across multiple length scales. Biopolymer-synthetic hybrid materials can assemble into supramolecular structures with a broad range of structural and functional diversity through precisely controlled noncovalent interactions between subunits. Despite recent progress, there is a need to understand the mechanisms underlying the assembly of biohybrid/synthetic molecular building blocks, which ultimately control the emergent properties of hierarchical assemblies. Here in this work, we study the concentration-driven self-assembly and gelation of π-conjugated synthetic oligopeptides containing different π-conjugated cores (quaterthiophene and perylene diimide) using a combination of particlemore » tracking microrheology, confocal fluorescence microscopy, optical spectroscopy, and electron microscopy. Our results show that π-conjugated oligopeptides self-assemble into β-sheet-rich fiber-like structures at neutral pH, even in the absence of electrostatic screening of charged residues. A critical fiber formation concentration c fiber and a critical gel concentration c gel are determined for fiber-forming π-conjugated oligopeptides, and the linear viscoelastic moduli (storage modulus G' and loss modulus G") are determined across a wide range of peptide concentrations. These results suggest that the underlying chemical structure of the synthetic π-conjugated cores greatly influences the self-assembly process, such that oligopeptides appended to π-conjugated cores with greater torsional flexibility tend to form more robust fibers upon increasing peptide concentration compared to oligopeptides with sterically constrained cores. Overall, our work focuses on the molecular assembly of π-conjugated oligopeptides driven by concentration, which is controlled by a combination of enthalpic and entropic interactions between oligopeptide subunits.« less

Concentration-Driven Assembly and Sol–Gel Transition of π-Conjugated Oligopeptides

DOE PAGES

Zhou, Yuecheng; Li, Bo; Li, Songsong; ...

2017-08-17

Advances in supramolecular assembly have enabled the design and synthesis of functional materials with well-defined structures across multiple length scales. Biopolymer-synthetic hybrid materials can assemble into supramolecular structures with a broad range of structural and functional diversity through precisely controlled noncovalent interactions between subunits. Despite recent progress, there is a need to understand the mechanisms underlying the assembly of biohybrid/synthetic molecular building blocks, which ultimately control the emergent properties of hierarchical assemblies. Here in this work, we study the concentration-driven self-assembly and gelation of π-conjugated synthetic oligopeptides containing different π-conjugated cores (quaterthiophene and perylene diimide) using a combination of particlemore » tracking microrheology, confocal fluorescence microscopy, optical spectroscopy, and electron microscopy. Our results show that π-conjugated oligopeptides self-assemble into β-sheet-rich fiber-like structures at neutral pH, even in the absence of electrostatic screening of charged residues. A critical fiber formation concentration c fiber and a critical gel concentration c gel are determined for fiber-forming π-conjugated oligopeptides, and the linear viscoelastic moduli (storage modulus G' and loss modulus G") are determined across a wide range of peptide concentrations. These results suggest that the underlying chemical structure of the synthetic π-conjugated cores greatly influences the self-assembly process, such that oligopeptides appended to π-conjugated cores with greater torsional flexibility tend to form more robust fibers upon increasing peptide concentration compared to oligopeptides with sterically constrained cores. Overall, our work focuses on the molecular assembly of π-conjugated oligopeptides driven by concentration, which is controlled by a combination of enthalpic and entropic interactions between oligopeptide subunits.« less

NASA Tech Briefs, August 2012

NASA Technical Reports Server (NTRS)

2012-01-01

Topics covered include: Mars Science Laboratory Drill; Ultra-Compact Motor Controller; A Reversible Thermally Driven Pump for Use in a Sub-Kelvin Magnetic Refrigerator; Shape Memory Composite Hybrid Hinge; Binding Causes of Printed Wiring Assemblies with Card-Loks; Coring Sample Acquisition Tool; Joining and Assembly of Bulk Metallic Glass Composites Through Capacitive Discharge; 670-GHz Schottky Diode-Based Subharmonic Mixer with CPW Circuits and 70-GHz IF; Self-Nulling Lock-in Detection Electronics for Capacitance Probe Electrometer; Discontinuous Mode Power Supply; Optimal Dynamic Sub-Threshold Technique for Extreme Low Power Consumption for VLSI; Hardware for Accelerating N-Modular Redundant Systems for High-Reliability Computing; Blocking Filters with Enhanced Throughput for X-Ray Microcalorimetry; High-Thermal-Conductivity Fabrics; Imidazolium-Based Polymeric Materials as Alkaline Anion-Exchange Fuel Cell Membranes; Electrospun Nanofiber Coating of Fiber Materials: A Composite Toughening Approach; Experimental Modeling of Sterilization Effects for Atmospheric Entry Heating on Microorganisms; Saliva Preservative for Diagnostic Purposes; Hands-Free Transcranial Color Doppler Probe; Aerosol and Surface Parameter Retrievals for a Multi-Angle, Multiband Spectrometer LogScope; TraceContract; AIRS Maps from Space Processing Software; POSTMAN: Point of Sail Tacking for Maritime Autonomous Navigation; Space Operations Learning Center; OVERSMART Reporting Tool for Flow Computations Over Large Grid Systems; Large Eddy Simulation (LES) of Particle-Laden Temporal Mixing Layers; Projection of Stabilized Aerial Imagery Onto Digital Elevation Maps for Geo-Rectified and Jitter-Free Viewing; Iterative Transform Phase Diversity: An Image-Based Object and Wavefront Recovery; 3D Drop Size Distribution Extrapolation Algorithm Using a Single Disdrometer; Social Networking Adapted for Distributed Scientific Collaboration; General Methodology for Designing Spacecraft Trajectories; Hemispherical Field-of-View Above-Water Surface Imager for Submarines; and Quantum-Well Infrared Photodetector (QWIP) Focal Plane Assembly.

Infrared spectroscopy of large scale single layer graphene on self assembled organic monolayer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woo Kim, Nak; Youn Kim, Joo; Lee, Chul

2014-01-27

We study the effect of self-assembled monolayer (SAM) organic molecule substrate on large scale single layer graphene using infrared transmission measurement on Graphene/SAM/SiO{sub 2}/Si composite samples. From the Drude weight of the chemically inert CH{sub 3}-SAM, the electron-donating NH{sub 2}-SAM, and the SAM-less graphene, we determine the carrier density doped into graphene by the three sources—the SiO{sub 2} substrate, the gas-adsorption, and the functional group of the SAM's—separately. The SAM-treatment leads to the low carrier density N ∼ 4 × 10{sup 11} cm{sup −2} by blocking the dominant SiO{sub 2}- driven doping. The carrier scattering increases by the SAM-treatment rather than decreases. However, the transportmore » mobility is nevertheless improved due to the reduced carrier doping.« less

Comparing the new generation accelerator driven subcritical reactor system (ADS) to traditional critical reactors

NASA Astrophysics Data System (ADS)

Kemah, Elif; Akkaya, Recep; Tokgöz, Seyit Rıza

2017-02-01

In recent years, the accelerator driven subcritical reactors have taken great interest worldwide. The Accelerator Driven System (ADS) has been used to produce neutron in subcritical state by the external proton beam source. These reactors, which are hybrid systems, are important in production of clean and safe energy and conversion of radioactive waste. The ADS with the selection of reliability and robust target materials have been the new generation of fission reactors. In addition, in the ADS Reactors the problems of long-lived radioactive fission products and waste actinides encountered in the fission process of the reactor during incineration can be solved, and ADS has come to the forefront of thorium as fuel for the reactors.

Noninterceptive transverse emittance measurements using BPM for Chinese ADS R&D project

NASA Astrophysics Data System (ADS)

Wang, Zhi-Jun; Feng, Chi; He, Yuan; Dou, Weiping; Tao, Yue; Chen, Wei-long; Jia, Huan; Liu, Shu-hui; Wang, Wang-sheng; Zhang, Yong; Wu, Jian-qiang; Zhang, Sheng-hu; Zhang, X. L.

2016-04-01

The noninterceptive four-dimensional transverse emittance measurements are essential for commissioning the high power continue-wave (CW) proton linacs as well as their operations. The conventional emittance measuring devices such as slits and wire scanners are not well suited under these conditions due to sure beam damages. Therefore, the method of using noninterceptive Beam Position Monitor (BPM) is developed and demonstrated on Injector Scheme II at the Chinese Accelerator Driven Sub-critical System (China-ADS) proofing facility inside Institute of Modern Physics (IMP) [1]. The results of measurements are in good agreements with wire scanners and slits at low duty-factor pulsed (LDFP) beam. In this paper, the detailed experiment designs, data analysis and result benchmarking are presented.

Studies on Materials for Heavy-Liquid-Metal-Cooled Reactors in Japan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minoru Takahashi; Masayuki Igashira; Toru Obara

2002-07-01

Recent studies on materials for the development of lead-bismuth (Pb-Bi)-cooled fast reactors (FR) and accelerator-driven sub-critical systems (ADS) in Japan are reported. The measurement of the neutron cross section of Bi to produce {sup 210}Po, the removal experiment of Po contamination and steel corrosion test in Pb-Bi flow were performed in Tokyo Institute of Technology. A target material corrosion test was performed in the project of Transmutation Experimental Facility for ADS in Japan Atomic Energy Research Institute (JAERI). Steel corrosion test was started in Mitsui Engineering and Shipbuilding Co., LTD (MES). The feasibility study for FR cycle performed in Japanmore » Nuclear Cycle Institute (JNC) are described. (authors)« less

Field-Distortion Air-Insulated Switches for Next-Generation Pulsed-Power Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wisher, Matthew Louis; Johns, Owen M.; Breden, Eric Wayne

We have developed two advanced designs of a field-distortion air-insulated spark-gap switch that reduce the size of a linear-transformer-driver (LTD) brick. Both designs operate at 200 kV and a peak current of ~50 kA. At these parameters, both achieve a jitter of less than 2 ns and a prefire rate of ~0.1% over 5000 shots. We have reduced the number of switch parts and assembly steps, which has resulted in a more uniform, design-driven assembly process. We will characterize the performance of tungsten-copper and graphite electrodes, and two different electrode geometries. The new switch designs will substantially improve the electricalmore » and operational performance of next-generation pulsed-power accelerators.« less

Metal-Folded Single-Chain Nanoparticle: Nanoclusters and Self-Assembled Reduction-Responsive Sub-5-nm Discrete Subdomains.

PubMed

Cao, Hui; Cui, Zhigang; Gao, Pan; Ding, Yi; Zhu, Xuechao; Lu, Xinhua; Cai, Yuanli

2017-09-01

Easy access to discrete nanoclusters in metal-folded single-chain nanoparticles (metal-SCNPs) and independent ultrafine sudomains in the assemblies via coordination-driven self-assembly of hydrophilic copolymer containing 9% imidazole groups is reported herein. 1 H NMR, dynamic light scattering, and NMR diffusion-ordered spectroscopy results demonstrate self-assembly into metal-SCNPs (>70% imidazole-units folded) by neutralization in the presence of Cu(II) in water to pH 4.6. Further neutralization induces self-assembly of metal-SCNPs (pH 4.6-5.0) and shrinkage (pH 5.0-5.6), with concurrent restraining residual imidazole motifs and hydrophilic segment, which organized into constant nanoparticles over pH 5.6-7.5. Atomic force microscopy results evidence discrete 1.2 nm nanoclusters and sub-5-nm subdomains in metal-SCNP and assembled nanoparticle. Reduction of metal center using sodium ascorbate induces structural rearrangement to one order lower than the precursor. Enzyme mimic catalysis required media-tunable discrete ultrafine interiors in metal-SCNPs and assemblies have hence been achieved. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Applications of High Intensity Proton Accelerators

NASA Astrophysics Data System (ADS)

Raja, Rajendran; Mishra, Shekhar

2010-06-01

Superconducting radiofrequency linac development at Fermilab / S. D. Holmes -- Rare muon decay experiments / Y. Kuno -- Rare kaon decays / D. Bryman -- Muon collider / R. B. Palmer -- Neutrino factories / S. Geer -- ADS and its potential / J.-P. Revol -- ADS history in the USA / R. L. Sheffield and E. J. Pitcher -- Accelerator driven transmutation of waste: high power accelerator for the European ADS demonstrator / J. L. Biarrotte and T. Junquera -- Myrrha, technology development for the realisation of ADS in EU: current status & prospects for realisation / R. Fernandez ... [et al.] -- High intensity proton beam production with cyclotrons / J. Grillenberger and M. Seidel -- FFAG for high intensity proton accelerator / Y. Mori -- Kaon yields for 2 to 8 GeV proton beams / K. K. Gudima, N. V. Mokhov and S. I. Striganov -- Pion yield studies for proton driver beams of 2-8 GeV kinetic energy for stopped muon and low-energy muon decay experiments / S. I. Striganov -- J-Parc accelerator status and future plans / H. Kobayashi -- Simulation and verification of DPA in materials / N. V. Mokhov, I. L. Rakhno and S. I. Striganov -- Performance and operational experience of the CNGS facility / E. Gschwendtner -- Particle physics enabled with super-conducting RF technology - summary of working group 1 / D. Jaffe and R. Tschirhart -- Proton beam requirements for a neutrino factory and muon collider / M. S. Zisman -- Proton bunching options / R. B. Palmer -- CW SRF H linac as a proton driver for muon colliders and neutrino factories / M. Popovic, C. M. Ankenbrandt and R. P. Johnson -- Rapid cycling synchrotron option for Project X / W. Chou -- Linac-based proton driver for a neutrino factory / R. Garoby ... [et al.] -- Pion production for neutrino factories and muon colliders / N. V. Mokhov ... [et al.] -- Proton bunch compression strategies / V. Lebedev -- Accelerator test facility for muon collider and neutrino factory R&D / V. Shiltsev -- The superconducting RF linac for muon collider and neutrino factory - summary of working group 2 / J. Galambos, R. Garoby and S. Geer -- Prospects for a very high power CW SRF linac / R. A. Rimmer -- Indian accelerator program for ADS applications / V. C. Sahni and P. Singh -- Ion accelerator activities at VECC (particularly, operating at low temperature) / R. K. Bhandari -- Chinese efforts in high intensity proton accelerators / S. Fu, J. Wang and S. Fang -- ADSR activity in the UK / R. J. Barlow -- ADS development in Japan / K. Kikuchi -- Project-X, SRF, and very large power stations / C. M. Ankenbrandt, R. P. Johnson and M. Popovic -- Power production and ADS / R. Raja -- Experimental neutron source facility based on accelerator driven system / Y. Gohar -- Transmutation mission / W. S. Yang -- Safety performance and issues / J. E. Cahalan -- Spallation target design for accelerator-driven systems / Y. Gohar -- Design considerations for accelerator transmutation of waste system / W. S. Yang -- Japan ADS program / T. Sasa -- Overview of members states' and IAEA activities in the field of Accelerator Driven Systems (ADS) / A. Stanculescu -- Linac for ADS applications - accelerator technologies / R. W. Garnett and R. L. Sheffield -- SRF linacs and accelerator driven sub-critical systems - summary working groups 3 & 4 / J. Delayen -- Production of Actinium-225 via high energy proton induced spallation of Thorium-232 / J. Harvey ... [et al.] -- Search for the electric dipole moment of Radium-225 / R. J. Holt, Z.-T. Lu and R. Mueller -- SRF linac and material science and medicine - summary of working group 5 / J. Nolen, E. Pitcher and H. Kirk.

Z pinches as intense x-ray sources for high-energy density physics applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matzen, M.K.

1997-05-01

Fast Z-pinch implosions can efficiently convert the stored electrical energy in a pulsed-power accelerator into x rays. These x rays are produced when an imploding cylindrical plasma, driven by the magnetic field pressure associated with very large axial currents, stagnates upon the cylindrical axis of symmetry. On the Saturn pulsed-power accelerator [R. B. Spielman {ital et al.}, in {ital Proceedings of the 2nd International Conference on Dense Z Pinches}, Laguna Beach, CA, 1989, edited by N. R. Pereira, J. Davis, and N. Rostoker (American Institute of Physics, New York, 1989), p. 3] at Sandia National Laboratories, for example, currents ofmore » 6{endash}8 MA with a rise time of less than 50 ns are driven through cylindrically symmetric loads, producing implosion velocities as high as 10{sup 8}cm/s and x-ray energies exceeding 400 kJ. Hydromagnetic Rayleigh{endash}Taylor instabilities and cylindrical load symmetry are critical, limiting factors in determining the assembled plasma densities and temperatures, and thus in the x-ray energies and pulse widths that can be produced on these accelerators. In recent experiments on the Saturn accelerator, these implosion nonuniformities have been minimized by using wire arrays with as many as 192 wires. Increasing the wire number produced significant improvements in the pinched plasma quality, reproducibility, and x-ray output power. X-ray pulse widths of less than 5 ns and peak powers of 75{plus_minus}10TW have been achieved with arrays of 120 tungsten wires. Similar loads have recently been fielded on the Particle Beam Fusion Accelerator (PBFA II), producing x-ray energies in excess of 1.8 MJ at powers in excess of 160 TW. These intense x-ray sources offer the potential for performing many new basic physics and fusion-relevant experiments. {copyright} {ital 1997 American Institute of Physics.}« less

Novel MnOOH–graphene nanocomposites: Preparation, characterization and electrochemical properties for supercapacitors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mei, Jun; Zhang, Long, E-mail: zhanglongzhl@163.com

2015-01-15

In this paper, we report a simple and controlled synthesis of novel MnOOH–graphene nanocomposites with a one-step facile hydrothermal method. It is template-free and easy to reproduce. Electrochemical properties are investigated in different media. The values of specific capacitance achieved are 112 F g{sup −1} in 1 M Na{sub 2}SO{sub 4} and 165 F g{sup −1} in 6 M KOH electrolyte, respectively. The assembly of multiple branched MnOOH and graphene flakes results in synergistic effects, forming new electron transfer channels to accelerate electron transfer and provide the pseudocapacitance to increase the overall capacitance. The novel composites have potential applications inmore » the fields of supercapacitors, lithium battery and so on. - Graphical abstract: The MnOOH–graphene nanocomposites shows better specific capacitance with the values achieved 112 F g{sup −1} in 1 M Na{sub 2}SO{sub 4} and 165 F g{sup −1} in 6 M KOH electrolyte, respectively. - Highlights: • Novel MnOOH–graphene nanocomposites were prepared by a one-step hydrothermal method. • The assembly can form new electron transfer channels to accelerate electron transfer. • The capacitive and rate performances are enhanced in both neutral and alkaline medium.« less

Assembling supramolecular networks by halogen bonding in coordination polymers driven by 5-bromonicotinic acid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gu, Jin-Zhong, E-mail: gujzh@lzu.edu.cn; Wu, Jiang; Kirillov, Alexander M.

2014-05-01

A series of six coordination compounds ([Zn(5-Brnic){sub 2}]·1.5H{sub 2}O){sub n} (1), [Cd(5-Brnic){sub 2}]{sub n} (2), [Co(5-Brnic){sub 2}(H{sub 2}O){sub 2}]{sub n} (3), [Zn(5-Brnic){sub 2}(H{sub 2}biim)]{sub n} (4), ([Cd(5-Brnic){sub 2}(phen)]·H{sub 2}O){sub n} (5), and [Pb(5-Brnic){sub 2}(phen)] (6) have been generated by the hydrothermal method from the metal(II) nitrates, 5-bromonicotinic acid (5-BrnicH), and an optional ancillary 1,10-phenanthroline (phen) or 2,2′-biimidazole (H{sub 2}biim) ligand. All the products 1–6 have been characterized by IR spectroscopy, elemental, thermal, powder and single-crystal X-ray diffraction analyses. Their 5-bromonicotinate-driven structures vary from the 3D metal-organic framework with the seh-3,5-P21/c topology (in 2) and the 2D interdigitated layers with themore » sql topology (in 1 and 3), to the 1D chains (in 4 and 5) and the 0D discrete monomers (in 6). The 5-bromonicotinate moiety acts as a versatile building block and its tethered bromine atom plays a key role in reinforcing and extending the structures into diverse 3D supramolecular networks via the various halogen bonding Br⋯O, Br⋯Br, and Br⋯π interactions, as well as the N–H⋯O and C–H⋯O hydrogen bonds. The obtained results demonstrate a useful guideline toward engineering the supramolecular architectures in the coordination network assembly under the influence of various halogen bonding interactions. The luminescent (for 1, 2, 4, 5, and 6) and magnetic (for 3) properties have also been studied and discussed in detail. - Graphical abstract: Six coordination compounds driven by 5-bromonicotinic acid have been generated and structurally characterized, revealing diverse metal-organic networks that are further reinforced and extended via various halogen bonding interactions. - Highlights: • 5-Bromonicotinic acid is a versatile ligand for Zn, Cd, Co and Pb derivatives. • Careful selection of co-ligands and metals resulted in different network structures. • Halogen and hydrogen bonding interactions lead to various supramolecular networks. • Luminescent and magnetic properties were studied and discussed in detail.« less

A Case Study Using Modeling and Simulation to Predict Logistics Supply Chain Issues

NASA Technical Reports Server (NTRS)

Tucker, David A.

2007-01-01

Optimization of critical supply chains to deliver thousands of parts, materials, sub-assemblies, and vehicle structures as needed is vital to the success of the Constellation Program. Thorough analysis needs to be performed on the integrated supply chain processes to plan, source, make, deliver, and return critical items efficiently. Process modeling provides simulation technology-based, predictive solutions for supply chain problems which enable decision makers to reduce costs, accelerate cycle time and improve business performance. For example, United Space Alliance, LLC utilized this approach in late 2006 to build simulation models that recreated shuttle orbiter thruster failures and predicted the potential impact of thruster removals on logistics spare assets. The main objective was the early identification of possible problems in providing thruster spares for the remainder of the Shuttle Flight Manifest. After extensive analysis the model results were used to quantify potential problems and led to improvement actions in the supply chain. Similarly the proper modeling and analysis of Constellation parts, materials, operations, and information flows will help ensure the efficiency of the critical logistics supply chains and the overall success of the program.

Magnetic Materials Characterization and Modeling for the Enhanced Design of Magnetic Shielding of Cryomodules in Particle Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sah, Sanjay

Particle accelerators produce beams of high-energy particles, which are used for both fundamental and applied scientific research and are critical to the development of accelerator driven sub-critical reactor systems. An effective magnetic shield is very important to achieve higher quality factor (Qo) of the cryomodule of a particle accelerator. The allowed value of field inside the cavity due to all external fields (particularly the Earth’s magnetic field) is ~15 mG or less. The goal of this PhD dissertation is to comprehensively study the magnetic properties of commonly used magnetic shielding materials at both cryogenic and room temperatures. This knowledge canmore » be used for the enhanced design of magnetic shields of cryomodes (CM) in particle accelerators. To this end, we first studied the temperature dependent magnetization behavior (M-H curves) of Amumetal and A4K under different annealing and deformation conditions. This characterized the effect of stress or deformation induced during the manufacturing processes and subsequent restoration of high permeability with appropriate heat treatment. Next, an energy based stochastic model for temperature dependent anhysteretic magnetization behavior of ferromagnetic materials was proposed and benchmarked against experimental data. We show that this model is able to simulate and explain the magnetic behavior of as rolled, deformed and annealed amumetal and A4K over a large range of temperatures. The experimental results for permeability are then used in a finite element model (FEM) in COMSOL to evaluate the shielding effectiveness of multiple shield designs at room temperature as well as cryogenic temperature. This work could serve as a guideline for future design, development and fabrication of magnetic shields of CMs.« less

Measurement of Thermal Dependencies of PBG Fiber Properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laouar, Rachik

Photonic crystal fibers (PCFs) represent a class of optical fibers which have a wide spectrum of applications in the telecom and sensing industries. Currently, the Advanced Accelerator Research Department at SLAC is developing photonic bandgap particle accelerators, which are photonic crystal structures with a central defect used to accelerate electrons and achieve high longitudinal electric fields. Extremely compact and less costly than the traditional accelerators, these structures can support higher accelerating gradients and will open a new era in high energy physics as well as other fields of science. Based on direct laser acceleration in dielectric materials, the so calledmore » photonic band gap accelerators will benefit from mature laser and semiconductor industries. One of the key elements to direct laser acceleration in hollow core PCFs, is maintaining thermal and structural stability. Previous simulations demonstrate that accelerating modes are sensitive to the geometry of the defect region and the variations in the effective index. Unlike the telecom modes (for which over 95% of the energy propagates in the hollow core) most of the power of these modes is located in the glass at the periphery of the central hole which has a higher thermal constant than air ({gamma}{sub SiO{sub 2}} = 1.19 x 10{sup -6} 1/K, {gamma}{sub air} = -9 x 10{sup -7} 1/K with {gamma} = dn/dT). To fully control laser driven acceleration, we need to evaluate the thermal and structural consequences of such modes on the PCFs. We are conducting series of interferometric tests to quantify the dependencies of the HC-633-02 (NKT Photonics) propagation constant (k{sub z}) on temperature, vibration amplitude, stress and electric field strength. In this paper we will present the theoretical principles characterizing the thermal behavior of a PCF, the measurements realized for the fundamental telecom mode (TE{sub 00}), and the experimental demonstration of TM-like mode propagation in the HC-633-02 fiber.« less

High power ring methods and accelerator driven subcritical reactor application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tahar, Malek Haj

2016-08-07

High power proton accelerators allow providing, by spallation reaction, the neutron fluxes necessary in the synthesis of fissile material, starting from Uranium 238 or Thorium 232. This is the basis of the concept of sub-critical operation of a reactor, for energy production or nuclear waste transmutation, with the objective of achieving cleaner, safer and more efficient process than today’s technologies allow. Designing, building and operating a proton accelerator in the 500-1000 MeV energy range, CW regime, MW power class still remains a challenge nowadays. There is a limited number of installations at present achieving beam characteristics in that class, e.g.,more » PSI in Villigen, 590 MeV CW beam from a cyclotron, SNS in Oakland, 1 GeV pulsed beam from a linear accelerator, in addition to projects as the ESS in Europe, a 5 MW beam from a linear accelerator. Furthermore, coupling an accelerator to a sub-critical nuclear reactor is a challenging proposition: some of the key issues/requirements are the design of a spallation target to withstand high power densities as well as ensure the safety of the installation. These two domains are the grounds of the PhD work: the focus is on the high power ring methods in the frame of the KURRI FFAG collaboration in Japan: upgrade of the installation towards high intensity is crucial to demonstrate the high beam power capability of FFAG. Thus, modeling of the beam dynamics and benchmarking of different codes was undertaken to validate the simulation results. Experimental results revealed some major losses that need to be understood and eventually overcome. By developing analytical models that account for the field defects, one identified major sources of imperfection in the design of scaling FFAG that explain the important tune variations resulting in the crossing of several betatron resonances. A new formula is derived to compute the tunes and properties established that characterize the effect of the field imperfections on the transverse beam dynamics. The results obtained allow to develop a correction scheme to minimize the tune variations of the FFAG. This is the cornerstone of a new fixed tune non-scaling FFAG that represents a potential candidate for high power applications. As part of the developments towards high power at the KURRI FFAG, beam dynamics studies have to account for space charge effects. In that framework, models have been installed in the tracking code ZGOUBI to account for the self-interaction of the particles in the accelerator. Application to the FFAG studies is shown. Finally, one focused on the ADSR concept as a candidate to solve the problem of nuclear waste. In order to establish the accelerator requirements, one compared the performance of ADSR with other conventional critical reactors by means of the levelized cost of energy. A general comparison between the different accelerator technologies that can satisfy these requirements is finally presented. In summary, the main drawback of the ADSR technology is the high Levelized Cost Of Energy compared to other advanced reactor concepts that do not employ an accelerator. Nowadays, this is a show-stopper for any industrial application aiming at producing energy (without dealing with the waste problem). Besides, the reactor is not intrinsically safer than critical reactor concepts, given the complexity of managing the target interface between the accelerator and the reactor core.« less

Metal-organic and supramolecular networks driven by 5-chloronicotinic acid: Hydrothermal self-assembly synthesis, structural diversity, luminescent and magnetic properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, Zhu-Qing, E-mail: zqgao2008@163.com; Li, Hong-Jin; Gu, Jin-Zhong, E-mail: gujzh@lzu.edu.cn

2016-09-15

Four new crystalline solids, namely [Co{sub 2}(µ{sub 2}-5-Clnic){sub 2}(µ{sub 3}-5-Clnic){sub 2}(µ{sub 2}-H{sub 2}O)]{sub n} (1), [Co(5-Clnic){sub 2}(H{sub 2}O){sub 4}]·2(5-ClnicH) (2), [Pb(µ{sub 2}-5-Clnic){sub 2}(phen)]{sub n} (3), and [Cd(5-Clnic){sub 2}(phen){sub 2}]·3H{sub 2}O (4) were generated by hydrothermal self-assembly methods from the corresponding metal(II) chlorides, 5-chloronicotinic acid (5-ClnicH) as a principal building block, and 1,10-phenanthroline (phen) as an ancillary ligand (optional). All the products 1–4 were characterized by IR spectroscopy, elemental analysis, thermogravimetric (TGA), powder X-ray diffraction (PXRD) and single-crystal X-ray diffraction. Their structures range from an intricate 3D metal-organic network 1 with the 3,6T7 topology to a ladder-like 1D coordination polymer 3more » with the 2C1 topology, whereas compounds 2 and 4 are the discrete 0D monomers. The structures of 2 and 4 are further extended (0D→2D or 0D→3D) by hydrogen bonds, generating supramolecular networks with the 3,8L18 and ins topologies, respectively. Synthetic aspects, structural features, thermal stability, magnetic (for 1) and luminescent (for 3 and 4) properties were also investigated and discussed. - Graphical abstract: A new series of crystalline solids was self-assembled and fully characterized; their structural, topological, luminescent and magnetic features were investigated. Display Omitted.« less

Analysis of a water moderated critical assembly with anisn-Vitamin C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, L.

1979-03-01

A tightly packed water moderated /sup 233/UO/sub 2/--ThO/sub 2/ critical assembly was analyzed with the Vitamin C library and the 1-D S/s n/ code, ANISN (S/sub 8/,P/sub 3/). The purpose of the study was to provide validation of this calculational model as applied to water-cooled hybrid fusion blankets. The quantities compared were the core eigenvalue and various activation shapes. The calculated eigenvalue was 1.02 +- 0.01. The /sup 233/U fission and /sup 232/Th capture shapes were found to be in good agreement (+-5%) with experiment, except near water--metal boundaries where differences up to 24% were observed. No such error peakingmore » was observed in the /sup 232/Th fast fission shape. We conclude that the model provides good volume averaged reaction rates in water-cooled systems. However, care must be exercised near water boundaries where thermally dependent reaction rates are significantly underestimated.« less

Motion of the plasma critical layer during relativistic-electron laser interaction with immobile and comoving ion plasma for ion acceleration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sahai, Aakash A., E-mail: aakash.sahai@gmail.com

2014-05-15

We analyze the motion of the plasma critical layer by two different processes in the relativistic-electron laser-plasma interaction regime (a{sub 0}>1). The differences are highlighted when the critical layer ions are stationary in contrast to when they move with it. Controlling the speed of the plasma critical layer in this regime is essential for creating low-β traveling acceleration structures of sufficient laser-excited potential for laser ion accelerators. In Relativistically Induced Transparency Acceleration (RITA) scheme, the heavy plasma-ions are fixed and only trace-density light-ions are accelerated. The relativistic critical layer and the acceleration structure move longitudinally forward by laser inducing transparencymore » through apparent relativistic increase in electron mass. In the Radiation Pressure Acceleration (RPA) scheme, the whole plasma is longitudinally pushed forward under the action of the laser radiation pressure, possible only when plasma ions co-propagate with the laser front. In RPA, the acceleration structure velocity critically depends upon plasma-ion mass in addition to the laser intensity and plasma density. In RITA, mass of the heavy immobile plasma-ions does not affect the speed of the critical layer. Inertia of the bared immobile ions in RITA excites the charge separation potential, whereas RPA is not possible when ions are stationary.« less

Large-scale self-assembly of uniform submicron silver sulfide material driven by precise pressure control

NASA Astrophysics Data System (ADS)

Qi, Juanjuan; Chen, Ke; Zhang, Shuhao; Yang, Yun; Guo, Lin; Yang, Shihe

2017-03-01

The controllable self-assembly of nanosized building blocks into larger specific structures can provide an efficient method of synthesizing novel materials with excellent properties. The self-assembly of nanocrystals by assisted means is becoming an extremely active area of research, because it provides a method of producing large-scale advanced functional materials with potential applications in the areas of energy, electronics, optics, and biologics. In this study, we applied an efficient strategy, namely, the use of ‘pressure control’ to the assembly of silver sulfide (Ag2S) nanospheres with a diameter of approximately 33 nm into large-scale, uniform Ag2S sub-microspheres with a size of about 0.33 μm. More importantly, this strategy realizes the online control of the overall reaction system, including the pressure, reaction time, and temperature, and could also be used to easily fabricate other functional materials on an industrial scale. Moreover, the thermodynamics and kinetics parameters for the thermal decomposition of silver diethyldithiocarbamate (Ag(DDTC)) are also investigated to explore the formation mechanism of the Ag2S nanosized building blocks which can be assembled into uniform sub-micron scale architecture. As a method of producing sub-micron Ag2S particles by means of the pressure-controlled self-assembly of nanoparticles, we foresee this strategy being an efficient and universally applicable option for constructing other new building blocks and assembling novel and large functional micromaterials on an industrial scale.

Self assembled monolayers of octadecyltrichlorosilane for dielectric materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, Vijay, E-mail: cirivijaypilani@gmail.com; Mechanical Engineering Department, Birla Institute of Technology and Science-Pilani; Puri, Paridhi

2016-04-13

Treatment of surfaces to change the interaction of fluids with them is a critical step in constructing useful microfluidics devices, especially those used in biological applications. Selective modification of inorganic materials such as Si, SiO{sub 2} and Si{sub 3}N{sub 4} is of great interest in research and technology. We evaluated the chemical formation of OTS self-assembled monolayers on silicon substrates with different dielectric materials. Our investigations were focused on surface modification of formerly used common dielectric materials SiO{sub 2}, Si{sub 3}N{sub 4} and a-poly. The improvement of wetting behaviour and quality of monolayer films were characterized using Atomic force microscope,more » Scanning electron microscope, Contact angle goniometer, Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) monolayer deposited oxide surface.« less

MeV electron acceleration at 1kHz with <10 mJ laser pulses

NASA Astrophysics Data System (ADS)

Salehi, Fatholah; Goers, Andy; Hine, George; Feder, Linus; Kuk, Donghoon; Kim, Ki-Yong; Milchberg, Howard

2016-10-01

We demonstrate laser driven acceleration of electrons at 1 kHz repetition rate with pC charge above 1MeV per shot using < 10 mJ pulse energies focused on a near-critical density He or H2 gas jet. Using the H2 gas jet, electron acceleration to 0.5 MeV in 10 fC bunches was observed with laser pulse energy as low as 1.3mJ . Using a near-critical density gas jet sets the critical power required for relativistic self-focusing low enough for mJ scale laser pulses to self- focus and drive strong wakefields. Experiments and particle-in-cell simulations show that optimal drive pulse duration and chirp for maximum electron bunch charge and energy depends on the target gas species. High repetition rate, high charge, and short duration electron bunches driven by very modest pulse energies constitutes an ideal portable electron source for applications such as ultrafast electron diffraction experiments and high rep. rate γ-ray production. This work is supported by the US Department of Energy, the National Science Foundation, and the Air Force Office of Scientific Research.

Microcharge neutralization transport experiments and simulations for ion-driven inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olson, C.L.; Hanson, D.L.; Poukey, J.W.

Space charge neutralization for intense beams for inertial confinement fusion is usually assumed to be perfect. However, small charge clumps in the beam will not be totally charge neutralized, and the residual net minimum potential set by electron trapping (e{phi} {approx} {1/2}m{sub e}v{sup 2}{sub i}, where m{sub e} is the electron mass and v{sub i} is the ion velocity) may lead to a substantial microdivergence. Experiments on the SABRE accelerator and simulations with the IPROP computer code are being performed to assess this mechanism. The authors have successfully created a 5 mrad beam on the SABRE accelerator, by expanding themore » beam (a process consistent with Liouville`s theorem) and, by passing the beam through a plate with pinholes, they have created low divergence beamlets to study this mechanism. Results clearly show: (1) at low pressures, trapping does neutralize the beamlets, but only down to e{phi} {approx} {1/2}m{sub e}v{sup 2}{sub i}; and (2) at higher pressures ({approx} 0.1-1 Torr), plasma shielding does remove the effect.« less

Self-aligned blocking integration demonstration for critical sub-40nm pitch Mx level patterning

NASA Astrophysics Data System (ADS)

Raley, Angélique; Mohanty, Nihar; Sun, Xinghua; Farrell, Richard A.; Smith, Jeffrey T.; Ko, Akiteru; Metz, Andrew W.; Biolsi, Peter; Devilliers, Anton

2017-04-01

Multipatterning has enabled continued scaling of chip technology at the 28nm node and beyond. Selfaligned double patterning (SADP) and self-aligned quadruple patterning (SAQP) as well as Litho- Etch/Litho-Etch (LELE) iterations are widely used in the semiconductor industry to enable patterning at sub 193 immersion lithography resolutions for layers such as FIN, Gate and critical Metal lines. Multipatterning requires the use of multiple masks which is costly and increases process complexity as well as edge placement error variation driven mostly by overlay. To mitigate the strict overlay requirements for advanced technology nodes (7nm and below), a self-aligned blocking integration is desirable. This integration trades off the overlay requirement for an etch selectivity requirement and enables the cut mask overlay tolerance to be relaxed from half pitch to three times half pitch. Selfalignement has become the latest trend to enable scaling and self-aligned integrations are being pursued and investigated for various critical layers such as contact, via, metal patterning. In this paper we propose and demonstrate a low cost flexible self-aligned blocking strategy for critical metal layer patterning for 7nm and beyond from mask assembly to low -K dielectric etch. The integration is based on a 40nm pitch SADP flow with 2 cut masks compatible with either cut or block integration and employs dielectric films widely used in the back end of the line. As a consequence this approach is compatible with traditional etch, deposition and cleans tools that are optimized for dielectric etches. We will review the critical steps and selectivities required to enable this integration along with bench-marking of each integration option (cut vs. block).

10 CFR 810.8 - Activities requiring specific authorization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any..., fabricating, operating or maintaining major critical components for use in such reactors, accelerator-driven...

10 CFR 810.8 - Activities requiring specific authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any..., fabricating, operating or maintaining major critical components for use in such reactors, accelerator-driven...

10 CFR 810.8 - Activities requiring specific authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any..., fabricating, operating or maintaining major critical components for use in such reactors, accelerator-driven...

10 CFR 810.8 - Activities requiring specific authorization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any..., fabricating, operating or maintaining major critical components for use in such reactors, accelerator-driven...

10 CFR 810.8 - Activities requiring specific authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any..., fabricating, operating or maintaining major critical components for use in such reactors, accelerator-driven...

Ag@AgHPW as a plasmonic catalyst for visible-light photocatalytic degradation of environmentally harmful organic pollutants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Wenhui; Cao, Minhua, E-mail: caomh@bit.edu.cn; Li, Na

2013-06-01

Graphical abstract: Ag@Ag{sub x}H{sub 3−x}PW12O40 (Ag@AgHPW) nanoparticles (NPs), a new visible-light driven plasmonic photocatalyst, are prepared by a green photoreduction strategy without the addition of any surfactant, which show a high activity and stability for the degradation of methyl blue (MB) under visible light irradiation. - Highlights: • A new visible-light driven photocatalyst Ag@Ag{sub x}H{sub 3−x}PW{sub 12}O{sub 40} was designed. • The photocatalyst shows a high activity for the degradation of methyl blue. • The high activity can be ascribed to the synergy of photoexcited AgHPW and Ag. - Abstract: Ag@Ag{sub x}H{sub 3−x}PW{sub 12}O{sub 40} (Ag@AgHPW) nanoparticles (NPs), a newmore » visible-light driven plasmonic photocatalyst, are prepared by a green photoreduction strategy without the addition of any surfactant. They show strong absorption in the visible region because of the localized surface plasmon resonance (LSPR) of Ag NPs. This plasmonic photocatalyst shows a high activity and stability for the degradation of methyl blue (MB) under visible light irradiation, which could be attributed to the highly synergy of photoexcited Ag{sub x}H{sub 3−x}PW{sub 12}O{sub 40} (AgHPW) and plasmon-excited Ag NPs and the confinement effects at interfaces between polyoxometalates (POMs) and silver. POM anions have redox ability and high photocatalytic activity, whereas Ag NPs could effectively accelerate the separation of electrons and holes, both of which contribute to their high activity.« less

Tropical nighttime warming as a dominant driver of variability in the terrestrial carbon sink

Treesearch

William R. L. Anderegg; Ashley P. Ballantyne; W. Kolby Smith; Joseph Majkut; Sam Rabin; Claudie Beaulieu; Richard Birdsey; John P. Dunne; Richard A. Houghton; Ranga B. Myneni; Yude Pan; Jorge L. Sarmiento; Nathan Serota; Elena Shevliakova; Pieter Tans; Stephen W. Pacala

2015-01-01

The terrestrial biosphere is currently a strong carbon (C) sink but may switch to a source in the 21st century as climate-driven losses exceed CO2-driven C gains, thereby accelerating global warming. Although it has long been recognized that tropical climate plays a critical role in regulating interannual climate variability, the causal link...

Generation of sub-gigabar-pressure shocks by a hyper-velocity impact in the collider driven by laser-induced cavity pressure

NASA Astrophysics Data System (ADS)

Badziak, J.; Kucharik, M.; Liska, R.

2018-02-01

The generation of high-pressure shocks in the newly proposed collider in which the projectile impacting a solid target is driven by the laser-induced cavity pressure acceleration (LICPA) mechanism is investigated using two-dimensional hydrodynamic simulations. The dependence of parameters of the shock generated in the target by the impact of a gold projectile on the impacted target material and the laser driver energy is examined. It is found that both in case of low-density (CH, Al) and high-density (Au, Cu) solid targets the shock pressures in the sub-Gbar range can be produced in the LICPA-driven collider with the laser energy of only a few hundreds of joules, and the laser-to-shock energy conversion efficiency can reach values of 10 - 20 %, by an order of magnitude higher than the conversion efficiencies achieved with other laser-based methods used so far.

THE SPATIO-TEMPORAL EVOLUTION OF SOLAR FLARES OBSERVED WITH AIA/SDO: FRACTAL DIFFUSION, SUB-DIFFUSION, OR LOGISTIC GROWTH?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aschwanden, Markus J., E-mail: aschwanden@lmsal.com

2012-09-20

We explore the spatio-temporal evolution of solar flares by fitting a radial expansion model r(t) that consists of an exponentially growing acceleration phase, followed by a deceleration phase that is parameterized by the generalized diffusion function r(t){proportional_to}{kappa}(t - t{sub 1}){sup {beta}/2}, which includes the logistic growth limit ({beta} = 0), sub-diffusion ({beta} = 0-1), classical diffusion ({beta} = 1), super-diffusion ({beta} = 1-2), and the linear expansion limit ({beta} = 2). We analyze all M- and X-class flares observed with Geostationary Operational Environmental Satellite and Atmospheric Imaging Assembly/Solar Dynamics Observatory (SDO) during the first two years of the SDO mission,more » amounting to 155 events. We find that most flares operate in the sub-diffusive regime ({beta} = 0.53 {+-} 0.27), which we interpret in terms of anisotropic chain reactions of intermittent magnetic reconnection episodes in a low plasma-{beta} corona. We find a mean propagation speed of v = 15 {+-} 12 km s{sup -1}, with maximum speeds of v{sub max} = 80 {+-} 85 km s{sup -1} per flare, which is substantially slower than the sonic speeds expected for thermal diffusion of flare plasmas. The diffusive characteristics established here (for the first time for solar flares) is consistent with the fractal-diffusive self-organized criticality model, which predicted diffusive transport merely based on cellular automaton simulations.« less

Neutronics Benchmarks for the Utilization of Mixed-Oxide Fuel: Joint U.S./ Russian Progress Report for Fiscal Year 1997, Volume 4, Part 8 - Neutron Poison Plates in Assemblies Containing Homogeneous Mixtures of Polystyrene-Moderated Plutonium and Uranium Oxides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yavuz, M.

1999-05-01

In the 1970s at the Battelle Pacific Northwest Laboratory (PNL), a series of critical experiments using a remotely operated Split-Table Machine was performed with homogeneous mixtures of (Pu-U)O{sub 2}-polystyrene fuels in the form of square compacts having different heights. The experiments determined the critical geometric configurations of MOX fuel assemblies with and without neutron poison plates. With respect to PuO{sub 2} content and moderation [H/(Pu+U)atomic] ratio (MR), two different homogeneous (Pu-U) O{sub 2}-polystyrene mixtures were considered: Mixture (1) 14.62 wt% PuO{sub 2} with 30.6 MR, and Mixture (2) 30.3 wt% PuO{sub 2} with 2.8 MR. In all mixtures, the uraniummore » was depleted to about O.151 wt% U{sup 235}. Assemblies contained copper, copper-cadmium or aluminum neutron poison plates having thicknesses up to {approximately}2.5 cm. This evaluation contains 22 experiments for Mixture 1, and 10 for Mixture 2 compacts. For Mixture 1, there are 10 configurations with copper plates, 6 with aluminum, and 5 with copper-cadmium. One experiment contained no poison plate. For Mixture 2 compacts, there are 3 configurations with copper, 3 with aluminum, and 3 with copper-cadmium poison plates. One experiment contained no poison plate.« less

Giant surfactants of poly(ethylene oxide)- b-polystyrene-(molecular nanoparticle): nanoparticle-driven self-assembly with sub-10-nm nanostructures in thin films

NASA Astrophysics Data System (ADS)

Hsu, Chih-Hao; Lin, Zhiwei; Dong, Xue-Hui; Hsieh, I.-Fan; Cheng, Stephen Z. D.

2014-03-01

Giant surfactants are built upon precisely attaching shape- and volume-persistent molecular nanoparticles (MNP) to polymeric flexible tails. The unique class of self-assembling materials, giant surfactants, has been demonstrated to form self-assembled ordered nanostructures, and their self-assembly behaviors are remarkably sensitive to primary chemical structures. In this work, two sets of giant surfactants with functionalized MNP attached to diblock copolymer tails were studied in thin films. Carboxylic acid-functionalized [60]fullerene (AC60) tethered with PEO- b-PS (PEO-PS-AC60) represents an ABA' (hydrophilic-hydrophobic-hydrophilic) giant surfactant, and fluoro-functionalized polyhedral oligomeric silsesquioxane (FPOSS) tethered with PEO- b-PS (PEO-PS-FPOSS) represents an ABC (hydrophilic-hydrophobic-omniphobic) one. The dissimilar chemical natures of the MNPs result in different arrangement of MNPs in self-assembled structures, the dispersion of AC60 in PEO domain and the single domain of FPOSS. Moreover, the chemically bonded MNPs could induce the originally disordered small molecular PEO- b-PS to form ordered cylindrical and lamellar structure, as evidenced by TEM and GISAXS, leading to sub-10-nm nanostructures of copolymer in the thin film state.

Proton Mediated Chemistry and Catalysis in a Self-Assembled Supramolecular Host

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pluth, Michael; Bergman, Robert; Raymond, Kenneth

2009-04-10

Synthetic supramolecular host assemblies can impart unique reactivity to encapsulated guest molecules. Synthetic host molecules have been developed to carry out complex reactions within their cavities, despite the fact that they lack the type of specifically tailored functional groups normally located in the analogous active sites of enzymes. Over the past decade, the Raymond group has developed a series of self-assembled supramolecules and the Bergman group has developed and studied a number of catalytic transformations. In this Account, we detail recent collaborative work between these two groups, focusing on chemical catalysis stemming from the encapsulation of protonated guests and expandingmore » to acid catalysis in basic solution. We initially investigated the ability of a water-soluble, self-assembled supramolecular host molecule to encapsulate protonated guests in its hydrophobic core. Our study of encapsulated protonated amines revealed rich host-guest chemistry. We established that self-exchange (that is, in-out guest movement) rates of protonated amines were dependent on the steric bulk of the amine rather than its basicity. The host molecule has purely rotational tetrahedral (T) symmetry, so guests with geminal N-methyl groups (and their attendant mirror plane) were effectively desymmetrized; this allowed for the observation and quantification of the barriers for nitrogen inversion followed by bond rotation. Furthermore, small nitrogen heterocycles, such as N-alkylaziridines, N-alkylazetidines, and N-alkylpyrrolidines, were found to be encapsulated as proton-bound homodimers or homotrimers. We further investigated the thermodynamic stabilization of protonated amines, showing that encapsulation makes the amines more basic in the cavity. Encapsulation raises the effective basicity of protonated amines by up to 4.5 pK{sub a} units, a difference almost as large as that between the moderate and strong bases carbonate and hydroxide. The thermodynamic stabilization of protonated guests was translated into chemical catalysis by taking advantage of the potential for accelerating reactions that take place via positively charged transition states, which could be potentially stabilized by encapsulation. Orthoformates, generally stable in neutral or basic solution, were found to be suitable substrates for catalytic hydrolysis by the assembly. Orthoformates small enough to undergo encapsulation were readily hydrolyzed by the assembly in basic solution, with rate acceleration factors up to 3900 compared with those of the corresponding uncatalyzed reactions. Furthering the analogy to enzymes that obey Michaelis-Menten kinetics, we observed competitive inhibition with the inhibitor NPr{sub 4}{sup +}, thereby confirming that the interior cavity of the assembly was the active site for catalysis. Mechanistic studies revealed that the assembly is required for catalysis and that the rate-limiting step of the reaction involves proton transfer from hydronium to the encapsulated substrate. Encapsulation in the assembly changes the orthoformate hydrolysis from an A-1 mechanism (in which decomposition of the protonated substrate is the rate-limiting step) to an A-S{sub E}2 mechanism (in which proton transfer is the rate-limiting step). The study of hydrolysis in the assembly was next extended to acetals, which were also catalytically hydrolyzed by the assembly in basic solution. Acetal hydrolysis changed from the A-1 mechanism in solution to an A-2 mechanism inside the assembly, where attack of water on the protonated substrate is rate limiting. This work provides rare examples of assembly-catalyzed reactions that proceed with substantial rate accelerations despite the absence of functional groups in the cavity and with mechanisms fully elucidated by quantitative kinetic studies.« less

Intense, directed neutron beams from a laser-driven neutron source at PHELIX

NASA Astrophysics Data System (ADS)

Kleinschmidt, A.; Bagnoud, V.; Deppert, O.; Favalli, A.; Frydrych, S.; Hornung, J.; Jahn, D.; Schaumann, G.; Tebartz, A.; Wagner, F.; Wurden, G.; Zielbauer, B.; Roth, M.

2018-05-01

Laser-driven neutrons are generated by the conversion of laser-accelerated ions via nuclear reactions inside a converter material. We present results from an experimental campaign at the PHELIX laser at GSI in Darmstadt where protons and deuterons were accelerated from thin deuterated plastic foils with thicknesses in the μm and sub-μm range. The neutrons were generated inside a sandwich-type beryllium converter, leading to reproducible neutron numbers around 1011 neutrons per shot. The angular distribution was measured with a high level of detail using up to 30 bubble detectors simultaneously. It shows a laser forward directed component of up to 1.42 × 1010 neutrons per steradian, corresponding to a dose of 43 mrem scaled to a distance of 1 m from the converter.

Modeling pressure-driven assembly of polymer coated nanoparticles

NASA Astrophysics Data System (ADS)

Lane, J. Matthew D.; Salerno, K. Michael; Grest, Gary S.; Fan, Hongyou

2017-06-01

High-pressure experiments have successfully produced a variety of gold nanostructures by compressing polymer coated spherical nanoparticles. We apply atomistic simulation to understand the role of the soft polymer response in determining the pressure-driven assembly of gold nanostructures. Quasi-isentropic experiments have shown that 1D, 2D and 3D nanostructures can be formed and recovered from dynamic compression of fcc superlattices of alkanethiol-coated gold nanocrystals on Sandia's Veloce pulsed power accelerator. Molecular modeling has shown that the dimensionality of the final structures depends on the orientation of the superlattice and the uniaxial loading. We describe the role of coating ligand length and grafting density, on ligand migration and deformation processes during pressure-driven coalescence of the cores into permanent nanowires, nanosheets and 3D structures. The role of uniaxial vs isotropic pressure and the effects of compression along various superlattice orientations will be discussed. Sandia National Laboratories is a multi-mission laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Analysis of C/E results of fission rate ratio measurements in several fast lead VENUS-F cores

NASA Astrophysics Data System (ADS)

Kochetkov, Anatoly; Krása, Antonín; Baeten, Peter; Vittiglio, Guido; Wagemans, Jan; Bécares, Vicente; Bianchini, Giancarlo; Fabrizio, Valentina; Carta, Mario; Firpo, Gabriele; Fridman, Emil; Sarotto, Massimo

2017-09-01

During the GUINEVERE FP6 European project (2006-2011), the zero-power VENUS water-moderated reactor was modified into VENUS-F, a mock-up of a lead cooled fast spectrum system with solid components that can be operated in both critical and subcritical mode. The Fast Reactor Experiments for hybrid Applications (FREYA) FP7 project was launched in 2011 to support the designs of the MYRRHA Accelerator Driven System (ADS) and the ALFRED Lead Fast Reactor (LFR). Three VENUS-F critical core configurations, simulating the complex MYRRHA core design and one configuration devoted to the LFR ALFRED core conditions were investigated in 2015. The MYRRHA related cores simulated step by step design peculiarities like the BeO reflector and in pile sections. For all of these cores the fuel assemblies were of a simple design consisting of 30% enriched metallic uranium, lead rodlets to simulate the coolant and Al2O3 rodlets to simulate the oxide fuel. Fission rate ratios of minor actinides such as Np-237, Am-241 as well as Pu-239, Pu-240, Pu-242 and U-238 to U-235 were measured in these VENUS-F critical assemblies with small fission chambers in specially designed locations, to determine the spectral indices in the different neutron spectrum conditions. The measurements have been analyzed using advanced computational tools including deterministic and stochastic codes and different nuclear data sets like JEFF-3.1, JEFF-3.2, ENDF/B7.1 and JENDL-4.0. The analysis of the C/E discrepancies will help to improve the nuclear data in the specific energy region of fast neutron reactor spectra.

Laboratory flow experiments for visualizing carbon dioxide-induced, density-driven brine convection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kneafsey, T.; Pruess, K.

2009-09-01

Injection of carbon dioxide (CO{sub 2}) into saline aquifers confined by low-permeability cap rock will result in a layer of CO{sub 2} overlying the brine. Dissolution of CO{sub 2} into the brine increases the brine density, resulting in an unstable situation in which more-dense brine overlies less-dense brine. This gravitational instability could give rise to density-driven convection of the fluid, which is a favorable process of practical interest for CO{sub 2} storage security because it accelerates the transfer of buoyant CO{sub 2} into the aqueous phase, where it is no longer subject to an upward buoyant drive. Laboratory flow visualizationmore » tests in transparent Hele-Shaw cells have been performed to elucidate the processes and rates of this CO{sub 2} solute-driven convection (CSC). Upon introduction of CO{sub 2} into the system, a layer of CO{sub 2}-laden brine forms at the CO{sub 2}-water interface. Subsequently, small convective fingers form, which coalesce, broaden, and penetrate into the test cell. Images and time-series data of finger lengths and wavelengths are presented. Observed CO{sub 2} uptake of the convection system indicates that the CO{sub 2} dissolution rate is approximately constant for each test and is far greater than expected for a diffusion-only scenario. Numerical simulations of our system show good agreement with the experiments for onset time of convection and advancement of convective fingers. There are differences as well, the most prominent being the absence of cell-scale convection in the numerical simulations. This cell-scale convection observed in the experiments is probably initiated by a small temperature gradient induced by the cell illumination.« less

CHF considerations for highly moderated 100% MOX fuels PWRs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saphier, D.; Raymond, P.

1995-09-01

A feasibility study on using 100% MOX fuel in a PWR with increased moderating ratio, RMA, was initiated. In the proposed design all the parameters were chosen identical to the French 1450MW PWR, except the fuel pin diameter which was reduced to achieve higher moderating ratios, V{sub M}/V{sub F}, where V{sub M} and V{sub F} are the moderator and fuel volume respectively. Moderating ratios from 2 to 4 were considered. In the present study the thermal-hydraulic feasibility of using fuel assemblies with smaller diameter fuel pins was investigated. The major design constrain in this study was the critical heat fluxmore » (CHF). In order to maintain the fuel pin integrity under nominal operating and transient conditions, the minimum DNBR, (Departure from Nucleate Boiling Ratio given by CHF/q{close_quotes}{sub local}, where q{close_quotes}{sub local} is the local heat flux), has to be above a given value. The limitations of the existing CHF correlations for the present study are outlined. Two designs based on the conventional 17x17 fuel assembly and on the advanced 19x19 assembly meeting the MDNBR criteria and satisfying the control margin requirements, are proposed.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Q., E-mail: wuq@impcas.ac.cn; Ma, H. Y.; Yang, Y.

Two compact intense 2.45 GHz permanent magnet proton sources and their corresponding low energy beam transport (LEBT) system were developed successfully for China accelerator driven sub-critical system in 2014. Both the proton sources operate at 35 kV potential. The beams extracted from the ion source are transported by the LEBT, which is composed of two identical solenoids, to the 2.1 MeV Radio-Frequency Quadrupole (RFQ). In order to ensure the safety of the superconducting cavities during commissioning, an electrostatic-chopper has been designed and installed in the LEBT line that can chop the continuous wave beam into a pulsed one. The minimummore » width of the pulse is less than 10 μs and the fall/rise time of the chopper is about 20 ns. The performance of the proton source and the LEBT, such as beam current, beam profile, emittance and the impact to RFQ injection will be presented.« less

LBE water interaction in sub-critical reactors: First experimental and modelling results

NASA Astrophysics Data System (ADS)

Ciampichetti, A.; Agostini, P.; Benamati, G.; Bandini, G.; Pellini, D.; Forgione, N.; Oriolo, F.; Ambrosini, W.

2008-06-01

This paper concerns the study of the phenomena involved in the interaction between LBE and pressurised water which could occur in some hypothetical accidents in accelerator driven system type reactors. The LIFUS 5 facility was designed and built at ENEA-Brasimone to reproduce this kind of interaction in a wide range of conditions. The first test of the experimental program was carried out injecting water at 70 bar and 235 °C in a reaction vessel containing LBE at 1 bar and 350 °C. A pressurisation up to 80 bar was observed in the test section during the considered transient. The SIMMER III code was used to simulate the performed test. The calculated data agree in a satisfactory way with the experimental results giving confidence in the possibility to use this code for safety analyses of heavy liquid metal cooled reactors.

Calculation and analysis of cross-sections for p+184W reactions up to 200 MeV

NASA Astrophysics Data System (ADS)

Sun, Jian-Ping; Zhang, Zheng-Jun; Han, Yin-Lu

2015-08-01

A set of optimal proton optical potential parameters for p+ 184W reactions are obtained at incident proton energy up to 250 MeV. Based on these parameters, the reaction cross-sections, elastic scattering angular distributions, energy spectra and double differential cross sections of proton-induced reactions on 184W are calculated and analyzed by using theoretical models which integrate the optical model, distorted Born wave approximation theory, intra-nuclear cascade model, exciton model, Hauser-Feshbach theory and evaporation model. The calculated results are compared with existing experimental data and good agreement is achieved. Supported by National Basic Research Program of China, Technology Research of Accelerator Driven Sub-critical System for Nuclear Waste Transmutation (2007CB209903) and Strategic Priority Research Program of Chinese Academy of Sciences, Thorium Molten Salt Reactor Nuclear Energy System (XDA02010100)

Tailored electron bunches with smooth current profiles for enhanced transformer ratios in beam-driven acceleration

DOE PAGES

Lemery, F.; Piot, P.

2015-08-03

Collinear high-gradient O(GV/m) beam-driven wakefield methods for charged-particle acceleration could be critical to the realization of compact, cost-efficient, accelerators, e.g., in support of TeV-scale lepton colliders or multiple-user free-electron laser facilities. To make these options viable, the high accelerating fields need to be complemented with large transformer ratios >2, a parameter characterizing the efficiency of the energy transfer between a wakefield-exciting “drive” bunch to an accelerated “witness” bunch. While several potential current distributions have been discussed, their practical realization appears challenging due to their often discontinuous nature. In this paper we propose several alternative continuously differentiable (smooth) current profiles whichmore » support enhanced transformer ratios. We especially demonstrate that one of the devised shapes can be implemented in a photo-emission electron source by properly shaping the photocathode-laser pulse. We finally discuss a possible superconducting linear-accelerator concept that could produce shaped drive bunches at high-repetition rates to drive a dielectric-wakefield accelerator with accelerating fields on the order of ~60 MV/m and a transformer ratio ~5 consistent with a recently proposed multiuser free-electron laser facility.« less

Tailored electron bunches with smooth current profiles for enhanced transformer ratios in beam-driven acceleration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemery, F.; Piot, P.

Collinear high-gradient O(GV/m) beam-driven wakefield methods for charged-particle acceleration could be critical to the realization of compact, cost-efficient, accelerators, e.g., in support of TeV-scale lepton colliders or multiple-user free-electron laser facilities. To make these options viable, the high accelerating fields need to be complemented with large transformer ratios >2, a parameter characterizing the efficiency of the energy transfer between a wakefield-exciting “drive” bunch to an accelerated “witness” bunch. While several potential current distributions have been discussed, their practical realization appears challenging due to their often discontinuous nature. In this paper we propose several alternative continuously differentiable (smooth) current profiles whichmore » support enhanced transformer ratios. We especially demonstrate that one of the devised shapes can be implemented in a photo-emission electron source by properly shaping the photocathode-laser pulse. We finally discuss a possible superconducting linear-accelerator concept that could produce shaped drive bunches at high-repetition rates to drive a dielectric-wakefield accelerator with accelerating fields on the order of ~60 MV/m and a transformer ratio ~5 consistent with a recently proposed multiuser free-electron laser facility.« less

Accelerator-driven transmutation of spent fuel elements

DOEpatents

Venneri, Francesco; Williamson, Mark A.; Li, Ning

2002-01-01

An apparatus and method is described for transmuting higher actinides, plutonium and selected fission products in a liquid-fuel subcritical assembly. Uranium may also be enriched, thereby providing new fuel for use in conventional nuclear power plants. An accelerator provides the additional neutrons required to perform the processes. The size of the accelerator needed to complete fuel cycle closure depends on the neutron efficiency of the supported reactors and on the neutron spectrum of the actinide transmutation apparatus. Treatment of spent fuel from light water reactors (LWRs) using uranium-based fuel will require the largest accelerator power, whereas neutron-efficient high temperature gas reactors (HTGRs) or CANDU reactors will require the smallest accelerator power, especially if thorium is introduced into the newly generated fuel according to the teachings of the present invention. Fast spectrum actinide transmutation apparatus (based on liquid-metal fuel) will take full advantage of the accelerator-produced source neutrons and provide maximum utilization of the actinide-generated fission neutrons. However, near-thermal transmutation apparatus will require lower standing

Controllable robust laser driven ion acceleration from near-critical density relativistic self-transparent plasma

NASA Astrophysics Data System (ADS)

Liu, Bin; Meyer-Ter-Vehn, Juergen; Ruhl, Hartmut

2017-10-01

We introduce an alternative approach for laser driven self-injected high quality ion acceleration. We call it ion wave breaking acceleration. It operates in relativistic self-transparent plasma for ultra-intense ultra-short laser pulses. Laser propagating in a transparent plasma excites an electron wave as well as an ion wave. When the ion wave breaks, a fraction of ions is self-injected into the positive part of the laser driven wake. This leads to a superior ion pulse with peaked energy spectra; in particular in realistic three-dimensional geometry, the injection occurs localized close to the laser axis producing highly directed bunches. A theory is developed to investigate the ion wave breaking dynamics. Three dimensional Particle-in-Cell simulations with pure-gaussian laser pulses and pre-expanded near-critical density plasma targets have been done to verify the theoretical results. It is shown that hundreds of MeV, easily controllable and manipulable, micron-scale size, highly collimated and quasi-mono-energetic ion beams can be produced by using ultra-intense ultra-short laser pulses with total laser energies less than 10 Joules. Such ion beams may find important applications in tumour therapy. B. Liu acknowledges support from the Alexander von Humboldt Foundation. B. Liu and H. Ruhl acknowledge supports from the Gauss Centre for Supercomputing (GCS), and the Cluster-of-Excellence Munich Centre for Advanced Photonics (MAP).

High Energy electron and proton acceleration by circularly polarized laser pulse from near critical density hydrogen gas target.

PubMed

Sharma, Ashutosh

2018-02-01

Relativistic electron rings hold the possibility of very high accelerating rates, and hopefully a relatively cheap and compact accelerator/collimator for ultrahigh energy proton source. In this work, we investigate the generation of helical shaped quasi-monoenergetic relativistic electron beam and high-energy proton beam from near critical density plasmas driven by petawatt-circularly polarized-short laser pulses. We numerically observe the efficient proton acceleration from magnetic vortex acceleration mechanism by using the three dimensional particle-in-cell simulations; proton beam with peak energy 350 MeV, charge ~10nC and conversion efficiency more than 6% (which implies 2.4 J proton beam out of the 40 J incident laser energy) is reported. We detailed the microphysics involved in the ion acceleration mechanism, which requires investigating the role of self-generated plasma electric and magnetic fields. The concept of efficient generation of quasi-monoenergetic electron and proton beam from near critical density gas targets may be verified experimentally at advanced high power - high repetition rate laser facilities e.g. ELI-ALPS. Such study should be an important step towards the development of high quality electron and proton beam.

FAST ACTING CURRENT SWITCH

DOEpatents

Batzer, T.H.; Cummings, D.B.; Ryan, J.F.

1962-05-22

A high-current, fast-acting switch is designed for utilization as a crowbar switch in a high-current circuit such as used to generate the magnetic confinement field of a plasma-confining and heat device, e.g., Pyrotron. The device particularly comprises a cylindrical housing containing two stationary, cylindrical contacts between which a movable contact is bridged to close the switch. The movable contact is actuated by a differential-pressure, airdriven piston assembly also within the housing. To absorb the acceleration (and the shock imparted to the device by the rapidly driven, movable contact), an adjustable air buffer assembly is provided, integrally connected to the movable contact and piston assembly. Various safety locks and circuit-synchronizing means are also provided to permit proper cooperation of the invention and the high-current circuit in which it is installed. (AEC)

Iridium complexes for electrocatalysis

DOEpatents

Sheehan, Stafford Wheeler; Hintermair, Ulrich; Thomsen, Julianne M; Brudvig, Gary W; Crabtree, Robert H

2017-10-17

Solution-phase (e.g., homogeneous) or surface-immobilized (e.g., heterogeneous) electrode-driven oxidation catalysts based on iridium coordination compounds which self-assemble upon chemical or electrochemical oxidation of suitable precursors and methods of making and using thereof are. Iridium species such as {[Ir(LX).sub.x(H.sub.2O).sub.y(.mu.-O)].sub.z.sup.m+}.sub.n wherein x, y, m are integers from 0-4, z and n from 1-4 and LX is an oxidation-resistant chelate ligand or ligands, such as such as 2(2-pyridyl)-2-propanolate, form upon oxidation of various molecular iridium complexes, for instance [Cp*Ir(LX)OH] or [(cod)Ir(LX)] (Cp*=pentamethylcyclopentadienyl, cod=cis-cis,1,5-cyclooctadiene) when exposed to oxidative conditions, such as sodium periodate (NaIO.sub.4) in aqueous solution at ambient conditions.

Weibel instability mediated collisionless shocks using intense laser-driven plasmas

NASA Astrophysics Data System (ADS)

Palaniyappan, Sasi; Huang, Chengkun; Gautier, Donald; Fernandez, Juan; Ma, Wenjun; Schreiber, Jorg; LANL Collaboration; LMU Team

2016-10-01

The origin of cosmic rays remains a long-standing challenge in astrophysics and continues to fascinate physicists. It is believed that ``collisionless shocks'' - where the particle Coulomb mean free path is much larger that the shock transition - are a dominant source of energetic cosmic rays. These shocks are ubiquitous in astrophysical environments such as gamma-ray bursts, supernova remnants, pulsar wind nebula and coronal mass ejections from the sun. Several spacecraft observations have revealed acceleration of charged particles, mostly electrons, to very high energies with in the shock front. There is now also clear observational evidence that supernova remnant shocks accelerate both protons and electrons. The understanding of the microphysics behind collisionless shocks and their particle acceleration is tightly related with nonlinear basic plasma processes and remains a grand challenge. In this poster, we will present results from recent experiments at the LANL Trident laser facility studying collisionless shocks using intense ps laser (80J, 650 fs - peak intensity of 1020 W/cm2) driven near-critical plasmas using carbon nanotube foam targets. A second short pulse laser driven protons from few microns thick aluminum foil is used to image the laser-driven plasma.

Staging and laser acceleration of ions in underdense plasma

NASA Astrophysics Data System (ADS)

Ting, Antonio; Hafizi, Bahman; Helle, Michael; Chen, Yu-Hsin; Gordon, Daniel; Kaganovich, Dmitri; Polyanskiy, Mikhail; Pogorelsky, Igor; Babzien, Markus; Miao, Chenlong; Dover, Nicholas; Najmudin, Zulfikar; Ettlinger, Oliver

2017-03-01

Accelerating ions from rest in a plasma requires extra considerations because of their heavy mass. Low phase velocity fields or quasi-electrostatic fields are often necessary, either by operating above or near the critical density or by applying other slow wave generating mechanisms. Solid targets have been a favorite and have generated many good results. High density gas targets have also been reported to produce energetic ions. It is interesting to consider acceleration of ions in laser-driven plasma configurations that will potentially allow continuous acceleration in multiple consecutive stages. The plasma will be derived from gaseous targets, producing plasma densities slightly below the critical plasma density (underdense) for the driving laser. Such a plasma is experimentally robust, being repeatable and relatively transparent to externally injected ions from a previous stage. When optimized, multiple stages of this underdense laser plasma acceleration mechanism can progressively accelerate the ions to a high final energy. For a light mass ion such as the proton, relativistic velocities could be reached, making it suitable for further acceleration by high phase velocity plasma accelerators to energies appropriate for High Energy Physics applications. Negatively charged ions such as antiprotons could be similarly accelerated in this multi-staged ion acceleration scheme.

Fission-Fusion: A new reaction mechanism for nuclear astrophysics based on laser-ion acceleration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thirolf, P. G.; Gross, M.; Allinger, K.

We propose to produce neutron-rich nuclei in the range of the astrophysical r-process around the waiting point N = 126 by fissioning a dense laser-accelerated thorium ion bunch in a thorium target (covered by a CH{sub 2} layer), where the light fission fragments of the beam fuse with the light fission fragments of the target. Via the 'hole-boring' mode of laser Radiation Pressure Acceleration using a high-intensity, short pulse laser, very efficiently bunches of {sup 232}Th with solid-state density can be generated from a Th target and a deuterated CD{sub 2} foil, both forming the production target assembly. Laser-accelerated Thmore » ions with about 7 MeV/u will pass through a thin CH{sub 2} layer placed in front of a thicker second Th foil (both forming the reaction target) closely behind the production target and disintegrate into light and heavy fission fragments. In addition, light ions (d,C) from the CD{sub 2} layer of the production target will be accelerated as well, inducing the fission process of {sup 232}Th also in the second Th layer. The laser-accelerated ion bunches with solid-state density, which are about 10{sup 14} times more dense than classically accelerated ion bunches, allow for a high probability that generated fission products can fuse again. The high ion beam density may lead to a strong collective modification of the stopping power, leading to significant range and thus yield enhancement. Using a high-intensity laser as envisaged for the ELI-Nuclear Physics project in Bucharest (ELI-NP), order-of-magnitude estimates promise a fusion yield of about 10{sup 3} ions per laser pulse in the mass range of A = 180-190, thus enabling to approach the r-process waiting point at N = 126.« less

Integrative pathway knowledge bases as a tool for systems molecular medicine.

PubMed

Liang, Mingyu

2007-08-20

There exists a sense of urgency to begin to generate a cohesive assembly of biomedical knowledge as the pace of knowledge accumulation accelerates. The urgency is in part driven by the emergence of systems molecular medicine that emphasizes the combination of systems analysis and molecular dissection in the future of medical practice and research. A potentially powerful approach is to build integrative pathway knowledge bases that link organ systems function with molecules.

Force Sensing Applications of DNA Origami Nanodevices

NASA Astrophysics Data System (ADS)

Hudoba, Michael William

Mechanical forces in biological systems vary in both length and magnitude by orders of magnitude making them difficult to probe and characterize with existing experimental methodologies. From molecules to cells, forces can act across length scales of nanometers to microns at magnitudes ranging from picoNewtons to nanoNewtons. Although single-molecule techniques such as optical traps, magnetic tweezers, and atomic force microscopy have improved the resolution and sensitivity of such measurements, inherent drawbacks exist in their capabilities due to the nature of the tools themselves. Specifically, these techniques have limitations in their ability to measure forces in realistic cellular environments and are not amenable to in vivo applications or measurements in mimicked physiological environments. In this thesis, we present a method to develop DNA force-sensing nanodevices with sub-picoNewton resolution capable of measuring forces in realistic cellular environments, with future applications in vivo. We use a design technique known as DNA origami to assemble devices with nanoscale geometric precision through molecular self-assembly via Watson-Crick base pairing. The devices have multiple conformational states, monitored by observing a Forster Resonance Energy Transfer signal that can change under the application of force. We expanded this study by demonstrating the design of responsive structural dynamics in DNA-based nanodevices. While prior studies have relied on external inputs to drive relatively slow dynamics in DNA nanostructures, here we developed DNA nanodevices with thermally driven dynamic function. The device was designed with an ensemble of conformations, and we establish methods to tune the equilibrium distribution of conformations and the rate of switching between states. We also show this nanodynamic behavior is responsive to physical interactions with the environment by measuring molecular crowding forces in the sub-picoNewton range, which are known to play a critical role in regulating molecular interactions and processes. Broadly, this work establishes a foundation for nanodevices with thermally driven dynamics that enable new measurement and control functions. We also examine the effect that forces have on the mechanical properties of DNA origami devices by developing a method to automate mesh generation for Finite Element Analysis. With this approach we are able to determine how defects that arise during assembly affect mechanical strain within structures during force application that can ultimately lead to device failure.

Direct assembling methodologies for high-throughput bioscreening

PubMed Central

Rodríguez-Dévora, Jorge I.; Shi, Zhi-dong; Xu, Tao

2012-01-01

Over the last few decades, high-throughput (HT) bioscreening, a technique that allows rapid screening of biochemical compound libraries against biological targets, has been widely used in drug discovery, stem cell research, development of new biomaterials, and genomics research. To achieve these ambitions, scaffold-free (or direct) assembly of biological entities of interest has become critical. Appropriate assembling methodologies are required to build an efficient HT bioscreening platform. The development of contact and non-contact assembling systems as a practical solution has been driven by a variety of essential attributes of the bioscreening system, such as miniaturization, high throughput, and high precision. The present article reviews recent progress on these assembling technologies utilized for the construction of HT bioscreening platforms. PMID:22021162

DE-1 observations of polar O(+) stream bulk parameters and comparison with a model of the centrifugally-accelerated polar wind

NASA Technical Reports Server (NTRS)

Ho, C. Wing; Horwitz, J. L.

1995-01-01

A survey of bulk parameters of analyzable O(+) outward streams in the mid-altitude (3-4.7 R(sub E) geocentric distance) polar cap magnetosphere is obtained from measurements by the Retarding Ion Mass Spectrometer (RIMS) aboard the Dynamics Explorer-1 (DE-1) spacecraft. There is wide scatter in the obtained densities, but they do display discernible trends: the average O(+) density in these streams decreases from about 60 ions/cc at 3.5 R(sub E) to about 1 ion/cc at 4.6 R(sub E). The streaming velocities are somewhat more defined, and their average increases from about 8 km/s at 3.5 R(sub E) to about 12 km/s at 4.6 R(sub E). The densities and bulk velocities are inversely correlated. We have further compared these observational trends with model profiles for the centrifugally-accelerated polar wind as recently described by Horwitz et al. (1994). The large outflow velocities observed can be understood in part as centrifugally-driven by convection with ionospheric electric field magnitudes of the order 50-70 mV/m, perhaps including plasma expansion effects.

Stellar winds in binary X-ray systems

NASA Technical Reports Server (NTRS)

Macgregor, K. B.; Vitello, P. A. J.

1982-01-01

It is thought that accretion from a strong stellar wind by a compact object may be responsible for the X-ray emission from binary systems containing a massive early-type primary. To investigate the effect of X-ray heating and ionization on the mass transfer process in systems of this type, an idealized model is constructed for the flow of a radiation-driven wind in the presence of an X-ray source of specified luminosity, L sub x. It is noted that for low values of L sub x, X-ray photoionization gives rise to additional ions having spectral lines with wavelengths situated near the peak of the primary continuum flux distribution. As a consequence, the radiation force acting on the gas increases in relation to its value in the absence of X-rays, and the wind is accelerated to higher velocities. As L sub x is increased, the degree of ionization of the wind increases, and the magnitude of the radiation force is diminished in comparison with the case in which L sub x = 0. This reduction leads at first to a decrease in the wind velocity and ultimately (for L sub x sufficiently large) to the termination of radiatively driven mass loss.

DETERMINATION OF SPECIFIC NEUTRONIC REACTIVITY

DOEpatents

Dessauer, G.

1960-05-10

A method is given for production-line determination of the specific neutronic reactivity of such objects as individual nuclear fuel or neutron absorber elements and is notable for rapidity and apparatus simplicity. The object is incorporated in a slightly sub-critical chain fission reactive assembly having a discrete neutron source, thereby establishing a K/sub eff/ within the crucial range of 0.95 to 0.995. The range was found to afford, uniquely, flux- transient damped response in a niatter of seconds simultaneously with acceptable analytical sensitivity. The resulting neutron flux measured at a situs spaced from both object and source within the assembly serves as a calibrable indication of said reactivity.

Perspective: Toward "synthesis by design": Exploring atomic correlations during inorganic materials synthesis

NASA Astrophysics Data System (ADS)

Soderholm, L.; Mitchell, J. F.

2016-05-01

Synthesis of inorganic extended solids is a critical starting point from which real-world functional materials and their consequent technologies originate. However, unlike the rich mechanistic foundation of organic synthesis, with its underlying rules of assembly (e.g., functional groups and their reactivities), the synthesis of inorganic materials lacks an underpinning of such robust organizing principles. In the latter case, any such rules must account for the diversity of chemical species and bonding motifs inherent to inorganic materials and the potential impact of mass transport on kinetics, among other considerations. Without such assembly rules, there is less understanding, less predictive power, and ultimately less control of properties. Despite such hurdles, developing a mechanistic understanding for synthesis of inorganic extended solids would dramatically impact the range of new material discoveries and resulting new functionalities, warranting a broad call to explore what is possible. Here we discuss our recent approaches toward a mechanistic framework for the synthesis of bulk inorganic extended solids, in which either embryonic atomic correlations or fully developed phases in solutions or melts can be identified and tracked during product selection and crystallization. The approach hinges on the application of high-energy x-rays, with their penetrating power and large Q-range, to explore reaction pathways in situ. We illustrate this process using two examples: directed assembly of Zr clusters in aqueous solution and total phase awareness during crystallization from K-Cu-S melts. These examples provide a glimpse of what we see as a larger vision, in which large scale simulations, data-driven science, and in situ studies of atomic correlations combine to accelerate materials discovery and synthesis, based on the assembly of well-defined, prenucleated atomic correlations.

Perspective: Toward “synthesis by design”: Exploring atomic correlations during inorganic materials synthesis

DOE PAGES

Soderholm, L.; Mitchell, J. F.

2016-05-26

Synthesis of inorganic extended solids is a critical starting point from which real-world functional materials and their consequent technologies originate. However, unlike the rich mechanistic foundation of organic synthesis, with its underlying rules of assembly (e.g., functional groups and their reactivities), the synthesis of inorganic materials lacks an underpinning of such robust organizing principles. In the latter case, any such rules must account for the diversity of chemical species and bonding motifs inherent to inorganic materials and the potential impact of mass transport on kinetics, among other considerations. Without such assembly rules, there is less understanding, less predictive power, andmore » ultimately less control of properties. Despite such hurdles, developing a mechanistic understanding for synthesis of inorganic extended solids would dramatically impact the range of new material discoveries and resulting new functionalities, warranting a broad call to explore what is possible. Here we discuss our recent approaches toward a mechanistic framework for the synthesis of bulk inorganic extended solids, in which either embryonic atomic correlations or fully developed phases in solutions or melts can be identified and tracked during product selection and crystallization. The approach hinges on the application of high-energy x-rays, with their penetrating power and large Q-range, to explore reaction pathways in situ. We illustrate this process using two examples: directed assembly of Zr clusters in aqueous solution and total phase awareness during crystallization from K–Cu–S melts. These examples provide a glimpse of what we see as a larger vision, in which large scale simulations, data-driven science, and in situ studies of atomic correlations combine to accelerate materials discovery and synthesis, based on the assembly of well-defined, prenucleated atomic correlations.« less

Development of a moderator system for the High Brilliance Neutron Source project

NASA Astrophysics Data System (ADS)

Dabruck, J. P.; Cronert, T.; Rücker, U.; Bessler, Y.; Klaus, M.; Lange, C.; Butzek, M.; Hansen, W.; Nabbi, R.; Brückel, T.

2016-11-01

The project for an accelerator based high brilliance neutron source HBS driven by Forschungszentrum Jülich forsees the use of the nuclear Be(p,n) or Be(d,n) reaction with accelerated particles in the lower MeV energy range. The lower neutron production compared to spallation has to be compensated by improving the neutron extraction process and optimizing the brilliance. Design and optimiziation of the moderator system are conducted with MCNP and will be validated with measurements at the AKR-2 training reactor by means of a prototype assembly where, e.g., the effect of different liquid H2 ortho/para ratios will be investigated and controlled in realtime via online heat capacity measurements.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antonova, A. O., E-mail: anna-antonova-08@mail.ru; Reznik, S. N., E-mail: s.reznik@voliacable.com; Todorov, M. D., E-mail: mtod@tu-sofia.bg

We study dynamics of the Goodwin nonlinear accelerator business cycle model with periodic forced autonomous investment I{sub a}(t) = a(1 – cos ωt), where a and ω are the amplitude and the frequency of investment. We give examples of the parameters a and ω when the chaotic oscillations of income are possible. We find the critical values of amplitude a{sub cr} (ω): if a > a{sub cr} (ω) the period of the income equals to the driving period T=2π/ω.

Ancillary ligand-assisted assembly of C{sub 3}-symmetric 4,4′,4″-nitrilotribenzoic acid with divalent Zn{sup 2+} ions: Syntheses, topological structures, and photoluminescence properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cui, Li-Ting; Niu, Yan-Fei; Han, Jie, E-mail: chan@ouhk.edu.hk

4,4′,4″-nitrilotribenzoic acid (H{sub 3}L), a C{sub 3}-symmetric ligand, was found to self-assemble into two polymorphs driven by intermolecular hydrogen-bonding interactions. Reactions of this ligand with Zn{sup 2+} under solvothermal conditions resulted in four new coordination polymers bearing interesting structural motifs: [Zn{sub 2}(L){sub 2}(py){sub 2}]·2(H{sub 2}NMe{sub 2}){sup +}·DMF·2H{sub 2}O (1), [Zn{sub 2}(L)(H{sub 2}L)(bipy)]·1.5H{sub 2}O·Guest (2), [Zn{sub 2}(L){sub 2}(bipy)]·2(H{sub 2}NMe{sub 2}){sup +}·2DMF (3), and [Zn{sub 3}(L){sub 2}(bpa)]·2H{sub 2}O·Guest (4) (H{sub 3}L=4,4′,4′′-nitrilotribenzoic acid, DMF=dimethylformamide, py=pyridine, bipy=4,4′-bipyridine, bpa=1,2-bis(4-pyridyl)diazene). Single-crystal structural analysis revealed that compound 1 exhibits a rare example of twofold interpenetrating anionic 3D (3,3)-net framework containing helical channels, whereas in 2, the 3Dmore » pillar-layer structure generated from bipy-pillared Zn{sub 2}(L)(H{sub 2}L) layer is further reinforced by intermolecular hydrogen bonding among pairs of free –COOH units. Compound 3 shows an interesting entangled architecture of 2D→3D parallel polycatenation consisting five-coordinated Zn{sup 2+} ions. Compound 4 displays a 3D pillar-layer framework with trimeric Zn{sub 3}(CO{sub 2}){sub 6} serving as secondary building unit (SBU). The syntheses, structures, thermal stabilities, powder X-ray diffractions and solid-state photoluminescence properties for these crystalline materials have been carried out. In addition, supramolecular assembly of H{sub 3}L under solvothermal conditions will also be addressed. - Graphical abstract: Supramolecular assembly of 4,4′,4′′-nitrilotribenzoic acid and its ligand behavior toward Zn{sup 2+} were investigated, which exhibit two polymorphs of the free acid and four metal coordination polymers bearing interesting structural motifs. - Highlights: • Two polymorphs of H{sub 3}L showing different hydrogen-bonded network were obtained. • Tune over the structure of MOFs was achieved. • 1 has a 2-fold interpenetrating anionic 3D network containing helical channels. • Structures bearing free carboxylic acid (–COOH) unit are constructed in 2. • 3 represents a rare 2D+2D→3D catenation array containing five-coordinated Zn{sup 2+}.« less

ZPPR-20 phase D : a cylindrical assembly of polyethylene moderated U metal reflected by beryllium oxide and polyethylene.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lell, R.; Grimm, K.; McKnight, R.

The Zero Power Physics Reactor (ZPPR) fast critical facility was built at the Argonne National Laboratory-West (ANL-W) site in Idaho in 1969 to obtain neutron physics information necessary for the design of fast breeder reactors. The ZPPR-20D Benchmark Assembly was part of a series of cores built in Assembly 20 (References 1 through 3) of the ZPPR facility to provide data for developing a nuclear power source for space applications (SP-100). The assemblies were beryllium oxide reflected and had core fuel compositions containing enriched uranium fuel, niobium and rhenium. ZPPR-20 Phase C (HEU-MET-FAST-075) was built as the reference flight configuration.more » Two other configurations, Phases D and E, simulated accident scenarios. Phase D modeled the water immersion scenario during a launch accident, and Phase E (SUB-HEU-MET-FAST-001) modeled the earth burial scenario during a launch accident. Two configurations were recorded for the simulated water immersion accident scenario (Phase D); the critical configuration, documented here, and the subcritical configuration (SUB-HEU-MET-MIXED-001). Experiments in Assembly 20 Phases 20A through 20F were performed in 1988. The reference water immersion configuration for the ZPPR-20D assembly was obtained as reactor loading 129 on October 7, 1988 with a fissile mass of 167.477 kg and a reactivity of -4.626 {+-} 0.044{cents} (k {approx} 0.9997). The SP-100 core was to be constructed of highly enriched uranium nitride, niobium, rhenium and depleted lithium. The core design called for two enrichment zones with niobium-1% zirconium alloy fuel cladding and core structure. Rhenium was to be used as a fuel pin liner to provide shut down in the event of water immersion and flooding. The core coolant was to be depleted lithium metal ({sup 7}Li). The core was to be surrounded radially with a niobium reactor vessel and bypass which would carry the lithium coolant to the forward inlet plenum. Immediately inside the reactor vessel was a rhenium baffle which would act as a neutron curtain in the event of water immersion. A fission gas plenum and coolant inlet plenum were located axially forward of the core. Some material substitutions had to be made in mocking up the SP-100 design. The ZPPR-20 critical assemblies were fueled by 93% enriched uranium metal because uranium nitride, which was the SP-100 fuel type, was not available. ZPPR Assembly 20D was designed to simulate a water immersion accident. The water was simulated by polyethylene (CH{sub 2}), which contains a similar amount of hydrogen and has a similar density. A very accurate transformation to a simplified model is needed to make any of the ZPPR assemblies a practical criticality-safety benchmark. There is simply too much geometric detail in an exact model of a ZPPR assembly, particularly as complicated an assembly as ZPPR-20D. The transformation must reduce the detail to a practical level without masking any of the important features of the critical experiment. And it must do this without increasing the total uncertainty far beyond that of the original experiment. Such a transformation will be described in a later section. First, Assembly 20D was modeled in full detail--every plate, drawer, matrix tube, and air gap was modeled explicitly. Then the regionwise compositions and volumes from this model were converted to an RZ model. ZPPR Assembly 20D has been determined to be an acceptable criticality-safety benchmark experiment.« less

Dependence of synergy current driven by lower hybrid wave and electron cyclotron wave on the frequency and parallel refractive index of electron cyclotron wave for Tokamaks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, J.; Chen, S. Y., E-mail: sychen531@163.com; Tang, C. J.

2014-01-15

The physical mechanism of the synergy current driven by lower hybrid wave (LHW) and electron cyclotron wave (ECW) in tokamaks is investigated using theoretical analysis and simulation methods in the present paper. Research shows that the synergy relationship between the two waves in velocity space strongly depends on the frequency ω and parallel refractive index N{sub //} of ECW. For a given spectrum of LHW, the parameter range of ECW, in which the synergy current exists, can be predicted by theoretical analysis, and these results are consistent with the simulation results. It is shown that the synergy effect is mainlymore » caused by the electrons accelerated by both ECW and LHW, and the acceleration of these electrons requires that there is overlap of the resonance regions of the two waves in velocity space.« less

Current driven instabilities of an electromagnetically accelerated plasma

NASA Technical Reports Server (NTRS)

Chouetri, E. Y.; Kelly, A. J.; Jahn, R. G.

1988-01-01

A plasma instability that strongly influences the efficiency and lifetime of electromagnetic plasma accelerators was quantitatively measured. Experimental measurements of dispersion relations (wave phase velocities), spatial growth rates, and stability boundaries are reported. The measured critical wave parameters are in excellent agreement with theoretical instability boundary predictions. The instability is current driven and affects a wide spectrum of longitudinal (electrostatic) oscillations. Current driven instabilities, which are intrinsic to the high-current-carrying magnetized plasma of the magnetoplasmadynmic (MPD) accelerator, were investigated with a kinetic theoretical model based on first principles. Analytical limits of the appropriate dispersion relation yield unstable ion acoustic waves for T(i)/T(e) much less than 1 and electron acoustic waves for T(i)/T(e) much greater than 1. The resulting set of nonlinear equations for the case of T(i)/T(e) = 1, of most interest to the MPD thruster Plasma Wave Experiment, was numerically solved to yield a multiparameter set of stability boundaries. Under certain conditions, marginally stable waves traveling almost perpendicular to the magnetic field would travel at a velocity equal to that of the electron current. Such waves were termed current waves. Unstable current waves near the upper stability boundary were observed experimentally and are in accordance with theoretical predictions. This provides unambiguous proof of the existence of such instabilites in electromagnetic plasma accelerators.

Electron heating enhancement by frequency-chirped laser pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yazdani, E.; Afarideh, H., E-mail: hafarideh@aut.ac.ir; Sadighi-Bonabi, R., E-mail: Sadighi@sharif.ir

2014-09-14

Propagation of a chirped laser pulse with a circular polarization through an uprising plasma density profile is studied by using 1D-3V particle-in-cell simulation. The laser penetration depth is increased in an overdense plasma compared to an unchirped pulse. The induced transparency due to the laser frequency chirp results in an enhanced heating of hot electrons as well as increased maximum longitudinal electrostatic field at the back side of the solid target, which is very essential in target normal sheath acceleration regime of proton acceleration. For an applied chirp parameter between 0.008 and 0.01, the maximum amount of the electrostatic fieldmore » is improved by a factor of 2. Furthermore, it is noticed that for a chirped laser pulse with a₀=5, because of increasing the plasma transparency length, the laser pulse can penetrate up to about n{sub e}≈6n{sub c}, where n{sub c} is plasma critical density. It shows 63% increase in the effective critical density compared to the relativistic induced transparency regime for an unchirped condition.« less

Optimizing laser-driven proton acceleration from overdense targets

PubMed Central

Stockem Novo, A.; Kaluza, M. C.; Fonseca, R. A.; Silva, L. O.

2016-01-01

We demonstrate how to tune the main ion acceleration mechanism in laser-plasma interactions to collisionless shock acceleration, thus achieving control over the final ion beam properties (e. g. maximum energy, divergence, number of accelerated ions). We investigate this technique with three-dimensional particle-in-cell simulations and illustrate a possible experimental realisation. The setup consists of an isolated solid density target, which is preheated by a first laser pulse to initiate target expansion, and a second one to trigger acceleration. The timing between the two laser pulses allows to access all ion acceleration regimes, ranging from target normal sheath acceleration, to hole boring and collisionless shock acceleration. We further demonstrate that the most energetic ions are produced by collisionless shock acceleration, if the target density is near-critical, ne ≈ 0.5 ncr. A scaling of the laser power shows that 100 MeV protons may be achieved in the PW range. PMID:27435449

Nonlinear evolution of the Rayleigh-Taylor and Richtmyer-Meshkov instabilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dimonte, G

Scaled experiments on the nonlinear evolution of the Rayleigh- Taylor (RT) and Richtmyer-Meshkov (RM) instabilities are described under a variety, of conditions that occur in nature. At high Reynolds number, the mixing layer grows self-similarly - {alpha}{sub i}Agt{sup 2} for a constant acceleration (g), and as a power law t{sup {theta}{sub i}} for impulsive accelerations U{delta}(t) at low and high Mach numbers. The growth coefficients {alpha}{sub i} and {theta}{sub i} exponents are measured over a comprehensive range of Atwood numbers A. The RT instability is also investigated with Non- Newtonian materials which are independently characterized. A critical wavelength and amplitudemore » for instability is observed associated with the shear modulus and tensile yield of the material. The results are applicable from supernova explosions to geophysical flows subject to these hydrodynamic instabilities.« less

Numerical modeling of laser-driven ion acceleration from near-critical gas targets

NASA Astrophysics Data System (ADS)

Tatomirescu, Dragos; Vizman, Daniel; d’Humières, Emmanuel

2018-06-01

In the past two decades, laser-accelerated ion sources and their applications have been intensely researched. Recently, it has been shown through experiments that proton beams with characteristics comparable to those obtained with solid targets can be obtained from gaseous targets. By means of particle-in-cell simulations, this paper studies in detail the effects of a near-critical density gradient on ion and electron acceleration after the interaction with ultra high intensity lasers. We can observe that the peak density of the gas jet has a significant influence on the spectrum features. As the gas jet density increases, so does the peak energy of the central quasi-monoenergetic ion bunch due to the increase in laser absorption while at the same time having a broadening effect on the electron angular distribution.

Integrated nuclear data utilisation system for innovative reactors.

PubMed

Yamano, N; Hasegawa, A; Kato, K; Igashira, M

2005-01-01

A five-year research and development project on an integrated nuclear data utilisation system was initiated in 2002, for developing innovative nuclear energy systems such as accelerator-driven systems. The integrated nuclear data utilisation system will be constructed as a modular code system, which consists of two sub-systems: the nuclear data search and plotting sub-system, and the nuclear data processing and utilisation sub-system. The system will be operated with a graphical user interface in order to enable easy utilisation through the Internet by both nuclear design engineers and nuclear data evaluators. This paper presents an overview of the integrated nuclear data utilisation system, describes the development of a prototype system to examine the operability of the user interface and discusses specifications of the two sub-systems.

Neutronics Investigations for the Lower Part of a Westinghouse SVEA-96+ Assembly

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murphy, M.F.; Luethi, A.; Seiler, R.

2002-05-15

Accurate critical experiments have been performed for the validation of total fission (F{sub tot}) and {sup 238}U-capture (C{sub 8}) reaction rate distributions obtained with CASMO-4, HELIOS, BOXER, and MCNP4B for the lower axial region of a real Westinghouse SVEA-96+ fuel assembly. The assembly comprised fresh fuel with an average {sup 235}U enrichment of 4.02 wt%, a maximum enrichment of 4.74 wt%, 14 burnable-absorber fuel pins, and full-density water moderation. The experimental configuration investigated was core 1A of the LWR-PROTEUS Phase I project, where 61 different fuel pins, representing {approx}64% of the assembly, were gamma-scanned individually. Calculated (C) and measured (E)more » values have been compared in terms of C/E distributions. For F{sub tot}, the standard deviations are 1.2% for HELIOS, 0.9% for CASMO-4, 0.8% for MCNP4B, and 1.7% for BOXER. Standard deviations of 1.1% for HELIOS, CASMO-4, and MCNP4B and 1.2% for BOXER were obtained in the case of C{sub 8}. Despite the high degree of accuracy observed on the average, it was found that the five burnable-absorber fuel pins investigated showed a noticeable underprediction of F{sub tot}, quite systematically, for the deterministic codes evaluated (average C/E for the burnable-absorber fuel pins in the range 0.974 to 0.988, depending on the code)« less

Electric-field-driven magnetization reversal in square-shaped nanomagnet-based multiferroic heterostructure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peng, Ren-Ci; Nan, Ce-Wen, E-mail: jzw12@psu.edu, E-mail: cwnan@tsinghua.edu.cn; Wang, J. J., E-mail: jzw12@psu.edu, E-mail: cwnan@tsinghua.edu.cn

Based on phase field modeling and thermodynamic analysis, purely electric-field-driven magnetization reversal was shown to be possible in a multiferroic heterostructure of a square-shaped amorphous Co{sub 40}Fe{sub 40}B{sub 20} nanomagnet on top of a ferroelectric layer through electrostrain. The reversal is made possible by engineering the mutual interactions among the built-in uniaxial magnetic anisotropy, the geometry-dependent magnetic configuration anisotropy, and the magnetoelastic anisotropy. Particularly, the incorporation of the built-in uniaxial anisotropy made it possible to reverse magnetization with one single unipolar electrostrain pulse, which is simpler than previous designs involving the use of bipolar electrostrains and may alleviate ferroelectric fatigue.more » Critical conditions for triggering the magnetization reversal are identified.« less

Kinematics Simulation of the Cardan Shaft for Investigation of the Cardan Error in Catia V5

NASA Astrophysics Data System (ADS)

Hajdu, Štefan; Rolník, Ladislav; Švoš, Juraj

2016-12-01

The goal of this paper is the creation of kinematic systems of the cardan shaft in the CAD/CAM/CAE system CATIA V5 and analysis of three cases of assembly to determine upon which, angular accelerations had been observed between the input driving shaft, central cardan shaft and output driven shaft. The scientific result of this paper was to confirm the presence of cardan error and how this type of error can be successfully eliminated.

Two-color ionization injection using a plasma beatwave accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schroeder, C. B.; Benedetti, C.; Esarey, E.

Two-color laser ionization injection is a method to generate ultra-low emittance (sub-100 nm transverse normalized emittance) beams in a laser-driven plasma accelerator. A plasma beatwave accelerator is proposed to drive the plasma wave for ionization injection, where the beating of the lasers effectively produces a train of long-wavelength pulses. The plasma beatwave accelerator excites a large amplitude plasma wave with low peak laser electric fields, leaving atomically-bound electrons with low ionization potential. A short-wavelength, low-amplitude ionization injection laser pulse (with a small ponderomotive force and large peak electric field) is used to ionize the remaining bound electrons at a wakemore » phase suitable for trapping, generating an ultra-low emittance electron beam that is accelerated in the plasma wave. Using a plasma beatwave accelerator for wakefield excitation, compared to short-pulse wakefield excitation, allows for a lower amplitude injection laser pulse and, hence, a lower emittance beam may be generated.« less

Two-color ionization injection using a plasma beatwave accelerator

DOE PAGES

Schroeder, C. B.; Benedetti, C.; Esarey, E.; ...

2018-01-10

Two-color laser ionization injection is a method to generate ultra-low emittance (sub-100 nm transverse normalized emittance) beams in a laser-driven plasma accelerator. A plasma beatwave accelerator is proposed to drive the plasma wave for ionization injection, where the beating of the lasers effectively produces a train of long-wavelength pulses. The plasma beatwave accelerator excites a large amplitude plasma wave with low peak laser electric fields, leaving atomically-bound electrons with low ionization potential. A short-wavelength, low-amplitude ionization injection laser pulse (with a small ponderomotive force and large peak electric field) is used to ionize the remaining bound electrons at a wakemore » phase suitable for trapping, generating an ultra-low emittance electron beam that is accelerated in the plasma wave. Using a plasma beatwave accelerator for wakefield excitation, compared to short-pulse wakefield excitation, allows for a lower amplitude injection laser pulse and, hence, a lower emittance beam may be generated.« less

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

PubMed Central

Wei, Xi; Syed, Abeer; Mao, Pan; Han, Jongyoon; Song, Yong-Ak

2016-01-01

Polydimethylsiloxane (PDMS) is the prevailing building material to make microfluidic devices due to its ease of molding and bonding as well as its transparency. Due to the softness of the PDMS material, however, it is challenging to use PDMS for building nanochannels. The channels tend to collapse easily during plasma bonding. In this paper, we present an evaporation-driven self-assembly method of silica colloidal nanoparticles to create nanofluidic junctions with sub-50 nm pores between two microchannels. The pore size as well as the surface charge of the nanofluidic junction is tunable simply by changing the colloidal silica bead size and surface functionalization outside of the assembled microfluidic device in a vial before the self-assembly process. Using the self-assembly of nanoparticles with a bead size of 300 nm, 500 nm, and 900 nm, it was possible to fabricate a porous membrane with a pore size of ~45 nm, ~75 nm and ~135 nm, respectively. Under electrical potential, this nanoporous membrane initiated ion concentration polarization (ICP) acting as a cation-selective membrane to concentrate DNA by ~1,700 times within 15 min. This non-lithographic nanofabrication process opens up a new opportunity to build a tunable nanofluidic junction for the study of nanoscale transport processes of ions and molecules inside a PDMS microfluidic chip. PMID:27023724

Mapping of the thermal neutron distribution in the lead block assembly of the PS-211 experiment at CERN, using thermoluminescence and nuclear track detectors.

PubMed

Savvidis, E; Eleftheriadis, C A; Kitis, G

2002-01-01

The main purpose of the TARC (Transmutation by Adiabatic Resonance Crossing) experiment (PS-211), was to demonstrate the possibility to destroy efficiently Long-Lived Fission Fragments (LLFF) in Accelerator Driven Systems (ADS). The experimental set-up which consisted of a lead block with dimensions 3.3 x 3.3 x 3 m3, was installed in a CERN Proton Synchrotron (PS) beam line. The proton beam at 2.5 GeV/c and 3.5 GeV/c, was incident in the centre of the lead block assembly producing neutrons via spallation reactions. In this study, neutron flux measurements are presented in the lead block assembly using thermoluminescence and nuclear track detectors. The results are in good agreement with Monte Carlo calculations as well as with the results of the other methods used in the framework of the TARC experiment.

Transmutation of Nuclear Waste and the future MYRRHA Demonstrator

NASA Astrophysics Data System (ADS)

Mueller, Alex C.

2013-03-01

While a considerable and world-wide growth of the nuclear share in the global energy mix is desirable for many reasons, there are also, in particular in the "old world" major objections. These are both concerns about safety, in particular in the wake of the Fukushima nuclear accident and concerns about the long-term burden that is constituted by the radiotoxic waste from the spent fuel. With regard to the second topic, the present contribution will outline the concept of Partitioning & Transmutation (P&T), as scientific and technological answer. Deployment of P&T may use dedicated "Transmuter" or "Burner" reactors, using a fast neutron spectrum. For the transmutation of waste with a large content (up to 50%) of (very long-lived) Minor Actinides, a sub-critical reactor, using an external neutron source is a most attractive solution. It is constituted by coupling a proton accelerator, a spallation target and a subcritical core. This promising new technology is named ADS, for accelerator-driven system. The present paper aims at a short introduction into the field that has been characterized by a high collaborative activity during the last decade in Europe, in order to focus, in its later part, on the MYRRHA project as the European ADS technology demonstrator.

Refluxed electrons direct laser acceleration in ultrahigh laser and relativistic critical density plasma interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, J.; Science and Technology on Plasma Physics Laboratory, China Academy of Engineering Physics, P.O. Box 919-986, Mianyang 621900; Zhao, Z. Q.

2015-01-15

Refluxed electrons direct laser acceleration is proposed so as to generate a high-charge energetic electron beam. When a laser pulse is incident on a relativistic critical density target, the rising edge of the pulse heats the target and the sheath fields on the both sides of the target reflux some electrons inside the expanding target. These electrons can be trapped and accelerated due to the self-transparency and the negative longitudinal electrostatic field in the expanding target. Some of the electrons can be accelerated to energies exceeding the ponderomotive limit 1/2a{sub 0}{sup 2}mc{sup 2}. Effective temperature significantly above the ponderomotive scalingmore » is observed. Furthermore, due to the limited expanding length, the laser propagating instabilities are suppressed in the interaction. Thus, high collimated beams with tens of μC charge can be generated.« less

Simulation Studies of the Dielectric Grating as an Accelerating and Focusing Structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soong, Ken; Peralta, E.A.; Byer, R.L.

A grating-based design is a promising candidate for a laser-driven dielectric accelerator. Through simulations, we show the merits of a readily fabricated grating structure as an accelerating component. Additionally, we show that with a small design perturbation, the accelerating component can be converted into a focusing structure. The understanding of these two components is critical in the successful development of any complete accelerator. The concept of accelerating electrons with the tremendous electric fields found in lasers has been proposed for decades. However, until recently the realization of such an accelerator was not technologically feasible. Recent advances in the semiconductor industry,more » as well as advances in laser technology, have now made laser-driven dielectric accelerators imminent. The grating-based accelerator is one proposed design for a dielectric laser-driven accelerator. This design, which was introduced by Plettner, consists of a pair of opposing transparent binary gratings, illustrated in Fig. 1. The teeth of the gratings serve as a phase mask, ensuring a phase synchronicity between the electromagnetic field and the moving particles. The current grating accelerator design has the drive laser incident perpendicular to the substrate, which poses a laser-structure alignment complication. The next iteration of grating structure fabrication seeks to monolithically create an array of grating structures by etching the grating's vacuum channel into a fused silica wafer. With this method it is possible to have the drive laser confined to the plane of the wafer, thus ensuring alignment of the laser-and-structure, the two grating halves, and subsequent accelerator components. There has been previous work using 2-dimensional finite difference time domain (2D-FDTD) calculations to evaluate the performance of the grating accelerator structure. However, this work approximates the grating as an infinite structure and does not accurately model a realizable structure. In this paper, we will present a 3-dimensional frequency-domain simulation of both the infinite and the finite grating accelerator structure. Additionally, we will present a new scheme for a focusing structure based on a perturbation of the accelerating structure. We will present simulations of this proposed focusing structure and quantify the quality of the focusing fields.« less

Advanced Accelerator Development Strategy Report: DOE Advanced Accelerator Concepts Research Roadmap Workshop

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Over a full two day period, February 2–3, 2016, the Office of High Energy Physics convened a workshop in Gaithersburg, MD to seek community input on development of an Advanced Accelerator Concepts (AAC) research roadmap. The workshop was in response to a recommendation by the HEPAP Accelerator R&D Subpanel [1] [2] to “convene the university and laboratory proponents of advanced acceleration concepts to develop R&D roadmaps with a series of milestones and common down selection criteria towards the goal for constructing a multi-TeV e+e– collider” (the charge to the workshop can be found in Appendix A). During the workshop, proponentsmore » of laser-driven plasma wakefield acceleration (LWFA), particle-beam-driven plasma wakefield acceleration (PWFA), and dielectric wakefield acceleration (DWFA), along with a limited number of invited university and laboratory experts, presented and critically discussed individual concept roadmaps. The roadmap workshop was preceded by several preparatory workshops. The first day of the workshop featured presentation of three initial individual roadmaps with ample time for discussion. The individual roadmaps covered a time period extending until roughly 2040, with the end date assumed to be roughly appropriate for initial operation of a multi-TeV e+e– collider. The second day of the workshop comprised talks on synergies between the roadmaps and with global efforts, potential early applications, diagnostics needs, simulation needs, and beam issues and challenges related to a collider. During the last half of the day the roadmaps were revisited but with emphasis on the next five to ten years (as specifically requested in the charge) and on common challenges. The workshop concluded with critical and unanimous endorsement of the individual roadmaps and an extended discussion on the characteristics of the common challenges. (For the agenda and list of participants see Appendix B.)« less

Laser-driven injector of electrons for IOTA

NASA Astrophysics Data System (ADS)

Romanov, Aleksandr

2017-03-01

Fermilab is developing the Integrable Optics Test Accelerator (IOTA) ring for experiments on nonlinear integrable optics. The machine will operate with either electron beams of 150 MeV or proton beams of 2.5 MeV energies, respectively. The stability of integrable optics depends critically on the precision of the magnetic lattice, which demands the use of beam-based lattice measurements for optics correction. In the proton mode, the low-energy proton beam does not represent a good probe for this application; hence we consider the use of a low-intensity reverse-injected electron beam of matched momentum (70 MeV). Such an injector could be implemented with the use of laser-driven acceleration techniques. This report presents the consideration for a laser-plasma injector for IOTA and discusses the requirements determined by the ring design.

Mounting for Fabrication, Metrology, and Assembly of Full Shell Grazing Incidence Optics

NASA Technical Reports Server (NTRS)

Roche, Jacqueline M.; Gubarev, Mikhail V.; O'Dell, Stephen L.; Kolodziejczak, Jeffery; Weisskopf, Martin C.; Ramsey, Brian D.; Elsner, Ronald F.

2014-01-01

Future x-ray telescopes will likely require lightweight mirrors to attain the large collecting areas needed to accomplish the science objectives. Understanding and demonstrating processes now is critical to achieving sub-arcsecond performance in the future. Consequently, designs not only of the mirrors but of fixtures for supporting them during fabrication, metrology, handling, assembly, and testing must be adequately modeled and verified. To this end, MSFC is using finite-element modeling to study the effects of mounting on full-shell grazing-incidence mirrors, during all processes leading to flight mirror assemblies. Here we report initial results of this study.

New insights into membrane fouling in submerged MBR under sub-critical flux condition.

PubMed

Li, Jianfeng; Zhang, Xiuxiu; Cheng, Fangqin; Liu, Yu

2013-06-01

This study investigated the membrane fouling in MBRs under sub-critical flux condition. Results showed membrane fouling at subcritical flux evolved through a three-stage process: a slow linear increase in transmembrane pressure (TMP) (stage I), followed by an exponential increase in TMP (stage II), and finally a rapid linear TMP rise was observed at stage III. It was found that bound EPS would play a significant role in fouling development at stage I, while SMPs appeared to be the major contributor to self-accelerating fouling phenomena observed at stage II. At stage III, the entire membrane was covered by a cake layer of flocs, as the result, the fouling rate was likely determined by floc characteristics. This study offers new insights into the fouling development under sub-critical flux condition. Copyright © 2013 Elsevier Ltd. All rights reserved.

Development of a Stochastically-driven, Forward Predictive Performance Model for PEMFCs

NASA Astrophysics Data System (ADS)

Harvey, David Benjamin Paul

A one-dimensional multi-scale coupled, transient, and mechanistic performance model for a PEMFC membrane electrode assembly has been developed. The model explicitly includes each of the 5 layers within a membrane electrode assembly and solves for the transport of charge, heat, mass, species, dissolved water, and liquid water. Key features of the model include the use of a multi-step implementation of the HOR reaction on the anode, agglomerate catalyst sub-models for both the anode and cathode catalyst layers, a unique approach that links the composition of the catalyst layer to key properties within the agglomerate model and the implementation of a stochastic input-based approach for component material properties. The model employs a new methodology for validation using statistically varying input parameters and statistically-based experimental performance data; this model represents the first stochastic input driven unit cell performance model. The stochastic input driven performance model was used to identify optimal ionomer content within the cathode catalyst layer, demonstrate the role of material variation in potential low performing MEA materials, provide explanation for the performance of low-Pt loaded MEAs, and investigate the validity of transient-sweep experimental diagnostic methods.

Micro-bubbles and Micro-particles are Not Faithful Tracers of Turbulent Acceleration

NASA Astrophysics Data System (ADS)

Sun, Chao; Mathai, Varghese; Calzavarini, Enrico; Brons, Jon; Lohse, Detlef

2016-11-01

We report on the Lagrangian statistics of acceleration of small (sub-Kolmogorov) bubbles and tracer particles with Stokes number St <<1 in turbulent flow. At decreasing Reynolds number, the bubble accelerations show deviations from that of tracer particles, i.e. they deviate from the Heisenberg-Yaglom prediction and show a quicker decorrelation despite their small size and minute St. Using direct numerical simulations, we show that these effects arise due the drift of these particles through the turbulent flow. We theoretically predict this gravity-driven effect for developed isotropic turbulence, with the ratio of Stokes to Froude number or equivalently the particle drift-velocity governing the enhancement of acceleration variance and the reductions in correlation time and intermittency. Our predictions are in good agreement with experimental and numerical results. The present findings are relevant to a range of scenarios encompassing tiny bubbles and droplets that drift through the turbulent oceans and the atmosphere.

Transportation of part supply improvement in agricultural machinery assembly plant

NASA Astrophysics Data System (ADS)

Saysaman, Anusit; Chutima, Parames

2018-02-01

This research focused on the problem caused by the transportation of part supply in agricultural machinery assembly plant in Thailand, which is one of the processes that are critical to the whole production process. If poorly managed, it will affect transportation of part supply, the emergence of sink cost, quality problems, and the ability to respond to the needs of the customers in time. Since the competition in the agricultural machinery market is more intense, the efficiency of part transportation process has to be improved. In this study, the process of transporting parts of the plant was studied and it was found that the efficiency of the process of transporting parts from the sub assembly line to its main assembly line was 83%. The approach to the performance improvement is done by using the Lean tool to limit wastes based on the ECRS principle and applying pull production system by changing the transportation method to operate as milkrun for transportation of parts to synchronize with the part demands of the main assembly line. After the transportation of parts from sub-assembly line to the main assembly line was improved, the efficiency raised to 98% and transportation process cost was saved to 540,000 Baht per year.

Ion acceleration by laser hole-boring into plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pogorelsky, I. V.; Dover, N. P.; Babzien, M.

By experiment and simulations, we study the interaction of an intense CO{sub 2} laser pulse with slightly overcritical plasmas of fully ionized helium gas. Transverse optical probing is used to show a recession of the front plasma surface with an initial velocity >10{sup 6} m/s driven by hole-boring by the laser pulse and the resulting radiation pressure driven electrostatic shocks. The collisionless shock propagates through the plasma, dissipates into an ion-acoustic solitary wave, and eventually becomes collisional as it slows further. These observations are supported by PIC simulations which prove the conclusion that monoenergetic protons observed in our earlier reportedmore » experiment with a hydrogen jet result from ion trapping and reflection from a shock wave driven through the plasma.« less

Unaligned instruction relocation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.

In one embodiment, a computer-implemented method includes receiving source code to be compiled into an executable file for an unaligned instruction set architecture (ISA). Aligned assembled code is generated, by a computer processor. The aligned assembled code complies with an aligned ISA and includes aligned processor code for a processor and aligned accelerator code for an accelerator. A first linking pass is performed on the aligned assembled code, including relocating a first relocation target in the aligned accelerator code that refers to a first object outside the aligned accelerator code. Unaligned assembled code is generated in accordance with the unalignedmore » ISA and includes unaligned accelerator code for the accelerator and unaligned processor code for the processor. A second linking pass is performed on the unaligned assembled code, including relocating a second relocation target outside the unaligned accelerator code that refers to an object in the unaligned accelerator code.« less

Unaligned instruction relocation

DOEpatents

Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.; Sura, Zehra N.

2018-01-23

In one embodiment, a computer-implemented method includes receiving source code to be compiled into an executable file for an unaligned instruction set architecture (ISA). Aligned assembled code is generated, by a computer processor. The aligned assembled code complies with an aligned ISA and includes aligned processor code for a processor and aligned accelerator code for an accelerator. A first linking pass is performed on the aligned assembled code, including relocating a first relocation target in the aligned accelerator code that refers to a first object outside the aligned accelerator code. Unaligned assembled code is generated in accordance with the unaligned ISA and includes unaligned accelerator code for the accelerator and unaligned processor code for the processor. A second linking pass is performed on the unaligned assembled code, including relocating a second relocation target outside the unaligned accelerator code that refers to an object in the unaligned accelerator code.

Validation of Hansen-Roach library for highly enriched uranium metal systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wenz, T.R.; Busch, R.D.

The Hansen-Roach 16-group cross-section library has been validated for use in pure uranium metal systems by modeling the Godiva critical assembly using the neutronics transport theory code ONEDANT to perform effective multiplication factor (k{sub eff}) calculations. The cross-section library used contains data for 118 isotopes (34 unique elements), including the revised cross sections for {sup 235}U and {sup 238}U. The Godiva critical assembly is a 17.4-cm sphere composed of 93.7 wt% {sup 235}U, 1.0 wt% {sup 234}U, and 5.3 wt% {sup 238}U with an effective homogeneous density of 18.7 g/cm{sup 3}.

Total synthesis of (+/-)-strychnine via a [4 + 2]-cycloaddition/rearrangement cascade.

PubMed

Zhang, Hongjun; Boonsombat, Jutatip; Padwa, Albert

2007-01-18

A new strategy for the synthesis of the Strychnos alkaloid (+/-)-strychnine has been developed and is based on an intramolecular [4 + 2]-cycloaddition/rearrangement cascade of an indolyl-substituted amidofuran. The critical D-ring was assembled by an intramolecular palladium-catalyzed enolate-driven cross-coupling of an N-tethered vinyl iodide. [reaction: see text].

Total Synthesis of (±)-Strychnine via a [4+2]-Cycloaddition/Rearrangement Cascade

PubMed Central

Zhang, Hongjun; Boonsombat, Jutatip

2008-01-01

A new strategy for the synthesis of the Strychnos alkaloid (±)-strychnine has been developed and is based on an intramolecular [4+2]-cycloaddition/rearrangement cascade of an indolyl substituted amidofuran. The critical D-ring was assembled by an intramolecular palladium catalyzed enolate-driven cross-coupling of an N-tethered vinyl iodide. PMID:17217284

Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry.

PubMed

Bridwell-Rabb, Jennifer; Fox, Nicholas G; Tsai, Chi-Lin; Winn, Andrew M; Barondeau, David P

2014-08-05

Iron-sulfur clusters are ubiquitous protein cofactors with critical cellular functions. The mitochondrial Fe-S assembly complex, which consists of the cysteine desulfurase NFS1 and its accessory protein (ISD11), the Fe-S assembly protein (ISCU2), and frataxin (FXN), converts substrates l-cysteine, ferrous iron, and electrons into Fe-S clusters. The physiological function of FXN has received a tremendous amount of attention since the discovery that its loss is directly linked to the neurodegenerative disease Friedreich's ataxia. Previous in vitro results revealed a role for human FXN in activating the cysteine desulfurase and Fe-S cluster biosynthesis activities of the Fe-S assembly complex. Here we present radiolabeling experiments that indicate FXN accelerates the accumulation of sulfur on ISCU2 and that the resulting persulfide species is viable in the subsequent synthesis of Fe-S clusters. Additional mutagenesis, enzyme kinetic, UV-visible, and circular dichroism spectroscopic studies suggest conserved ISCU2 residue C104 is critical for FXN activation, whereas C35, C61, and C104 are all essential for Fe-S cluster formation on the assembly complex. These results cannot be fully explained by the hypothesis that FXN functions as an iron donor for Fe-S cluster biosynthesis, and further support an allosteric regulator role for FXN. Together, these results lead to an activation model in which FXN accelerates persulfide formation on NFS1 and favors a helix-to-coil interconversion on ISCU2 that facilitates the transfer of sulfur from NFS1 to ISCU2 as an initial step in Fe-S cluster biosynthesis.

Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

PubMed Central

2015-01-01

Iron–sulfur clusters are ubiquitous protein cofactors with critical cellular functions. The mitochondrial Fe–S assembly complex, which consists of the cysteine desulfurase NFS1 and its accessory protein (ISD11), the Fe–S assembly protein (ISCU2), and frataxin (FXN), converts substrates l-cysteine, ferrous iron, and electrons into Fe–S clusters. The physiological function of FXN has received a tremendous amount of attention since the discovery that its loss is directly linked to the neurodegenerative disease Friedreich’s ataxia. Previous in vitro results revealed a role for human FXN in activating the cysteine desulfurase and Fe–S cluster biosynthesis activities of the Fe–S assembly complex. Here we present radiolabeling experiments that indicate FXN accelerates the accumulation of sulfur on ISCU2 and that the resulting persulfide species is viable in the subsequent synthesis of Fe–S clusters. Additional mutagenesis, enzyme kinetic, UV–visible, and circular dichroism spectroscopic studies suggest conserved ISCU2 residue C104 is critical for FXN activation, whereas C35, C61, and C104 are all essential for Fe–S cluster formation on the assembly complex. These results cannot be fully explained by the hypothesis that FXN functions as an iron donor for Fe–S cluster biosynthesis, and further support an allosteric regulator role for FXN. Together, these results lead to an activation model in which FXN accelerates persulfide formation on NFS1 and favors a helix-to-coil interconversion on ISCU2 that facilitates the transfer of sulfur from NFS1 to ISCU2 as an initial step in Fe–S cluster biosynthesis. PMID:24971490

The radiobiology of laser-driven particle beams: focus on sub-lethal responses of normal human cells

NASA Astrophysics Data System (ADS)

Manti, L.; Perozziello, F. M.; Borghesi, M.; Candiano, G.; Chaudhary, P.; Cirrone, G. A. P.; Doria, D.; Gwynne, D.; Leanza, R.; Prise, K. M.; Romagnani, L.; Romano, F.; Scuderi, V.; Tramontana, A.

2017-03-01

Accelerated proton beams have become increasingly common for treating cancer. The need for cost and size reduction of particle accelerating machines has led to the pioneering investigation of optical ion acceleration techniques based on laser-plasma interactions as a possible alternative. Laser-matter interaction can produce extremely pulsed particle bursts of ultra-high dose rates (>= 109 Gy/s), largely exceeding those currently used in conventional proton therapy. Since biological effects of ionizing radiation are strongly affected by the spatio-temporal distribution of DNA-damaging events, the unprecedented physical features of such beams may modify cellular and tissue radiosensitivity to unexplored extents. Hence, clinical applications of laser-generated particles need thorough assessment of their radiobiological effectiveness. To date, the majority of studies have either used rodent cell lines or have focussed on cancer cell killing being local tumour control the main objective of radiotherapy. Conversely, very little data exist on sub-lethal cellular effects, of relevance to normal tissue integrity and secondary cancers, such as premature cellular senescence. Here, we discuss ultra-high dose rate radiobiology and present preliminary data obtained in normal human cells following irradiation by laser-accelerated protons at the LULI PICO2000 facility at Laser Lab Europe, France.

Polydispersity-Driven Block Copolymer Amphiphile Self-Assembly into Prolate-Spheroid Micelles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmitt, Andrew L.; Repollet-Pedrosa, Milton H.; Mahanthappa, Mahesh K.

The aqueous self-assembly behavior of polydisperse poly(ethylene oxide-b-1,4-butadiene-b-ethylene oxide) (OBO) macromolecular triblock amphiphiles is examined to discern the implications of continuous polydispersity in the hydrophobic block on the resulting aqueous micellar morphologies of otherwise monodisperse polymer surfactants. The chain length polydispersity and implicit composition polydispersity of these samples furnishes a distribution of preferred interfacial curvatures, resulting in dilute aqueous block copolymer dispersions exhibiting coexisting spherical and rod-like micelles with vesicles in a single sample with a O weight fraction, w{sub O}, of 0.18. At higher w{sub O} = 0.51-0.68, the peak in the interfacial curvature distribution shifts and we observemore » the formation of only American football-shaped micelles. We rationalize the formation of these anisotropically shaped aggregates based on the intrinsic distribution of preferred curvatures adopted by the polydisperse copolymer amphiphiles and on the relief of core block chain stretching by chain-length-dependent intramicellar segregation.« less

Hydrodynamic Capture of Particles by Micro-swimmers under Hele-Shaw Flows

NASA Astrophysics Data System (ADS)

Mishler, Grant; Tsang, Alan Cheng Hou; Pak, On Shun

2017-11-01

We explore a hydrodynamic capture mechanism of a driven particle by a micro-swimmer in confined microfluidic environments with an idealized model. The capture is mediated by the hydrodynamic interactions between the micro-swimmer, the driven particle, and the background flow. This capture mechanism relies on the existence of attractive stable equilibrium configurations between the driven particle and the micro-swimmer, which occurs when the background flow is larger than a certain critical threshold. Dynamics and stability of capture and non-capture events will be discussed. This study may have potential applications in the study of capture and delivery of therapeutic payloads by micro-swimmers as well as particle self-assembly under confinements.

Tuning the reactivity of Al/Fe{sub 2}O{sub 3} nanoenergetic materials via an approach combining soft template self-assembly with sol–gel process process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Tianfu; Wang, Zhen; Li, Guoping

2015-10-15

A bottom-up approach combining soft template self-assembly with sol–gel process, was adopted to prepare the assembled Al/Fe{sub 2}O{sub 3} nanoenergetic materials, assembly-Al/Fe{sub 2}O{sub 3} sample. The other two unassembled Al/Fe{sub 2}O{sub 3}a nanoenergetic materials, sol–gel–Al/Fe{sub 2}O{sub 3} sample and mixing-Al/Fe{sub 2}O{sub 3} sample, were prepared by sol–gel method and physical mixing method respectively. The assembly process within the preparation of the assembly-Al/Fe{sub 2}O{sub 3} sample was analyzed through the changes in the average hydrodynamic diameters of the particles and the micelles in solution. SEM, EDS and TEM tests were performed to demonstrate a significant improvement regarding to dispersity and arrangementsmore » of the Al and Fe{sub 2}O{sub 3} particles in the assembled samples, compared to that of the unassembled Al/Fe{sub 2}O{sub 3} samples. DSC test was employed to characterize the reactivity of the samples. The heat release of the assembled Al/Fe{sub 2}O{sub 3} sample was 2088 J/g, about 400 and 990 J/g more than that of the sol–gel–Al/Fe{sub 2}O{sub 3} sample and mixing-Al/Fe{sub 2}O{sub 3} sample, respectively. - Graphical abstract: Modified aluminum (Al) nanoparticles with hydrophobic surface assembled into the Brij S10 micelle in Fe(III) sol, then the well dispersed system was transformed into Al/Fe{sub 2}O{sub 3} nanoenergetic materials with high reactivity. - Highlights: • An approach combining soft template self-assembly with sol–gel process was adopted. • The aggregation of Al nanoparticles in the final product was reduced significantly. • The reactivity of Al/Fe{sub 2}O{sub 3} nanoenergetic materials was improved to a large extent.« less

Particle Acceleration in Two Converging Shocks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Xin; Wang, Na; Shan, Hao

2017-06-20

Observations by spacecraft such as ACE , STEREO , and others show that there are proton spectral “breaks” with energy E {sub br} at 1–10 MeV in some large CME-driven shocks. Generally, a single shock with the diffusive acceleration mechanism would not predict the “broken” energy spectrum. The present paper focuses on two converging shocks to identify this energy spectral feature. In this case, the converging shocks comprise one forward CME-driven shock on 2006 December 13 and another backward Earth bow shock. We simulate the detailed particle acceleration processes in the region of the converging shocks using the Monte Carlomore » method. As a result, we not only obtain an extended energy spectrum with an energy “tail” up to a few 10 MeV higher than that in previous single shock model, but also we find an energy spectral “break” occurring on ∼5.5 MeV. The predicted energy spectral shape is consistent with observations from multiple spacecraft. The spectral “break,” then, in this case is caused by the interaction between the CME shock and Earth’s bow shock, and otherwise would not be present if Earth were not in the path of the CME.« less

Special issue on compact x-ray sources

NASA Astrophysics Data System (ADS)

Hooker, Simon; Midorikawa, Katsumi; Rosenzweig, James

2014-04-01

Journal of Physics B: Atomic, Molecular and Optical Physics is delighted to announce a forthcoming special issue on compact x-ray sources, to appear in the winter of 2014, and invites you to submit a paper. The potential for high-brilliance x- and gamma-ray sources driven by advanced, compact accelerators has gained increasing attention in recent years. These novel sources—sometimes dubbed 'fifth generation sources'—will build on the revolutionary advance of the x-ray free-electron laser (FEL). New radiation sources of this type have widespread applications, including in ultra-fast imaging, diagnostic and therapeutic medicine, and studies of matter under extreme conditions. Rapid advances in compact accelerators and in FEL techniques make this an opportune moment to consider the opportunities which could be realized by bringing these two fields together. Further, the successful development of compact radiation sources driven by compact accelerators will be a significant milestone on the road to the development of high-gradient colliders able to operate at the frontiers of particle physics. Thus the time is right to publish a peer-reviewed collection of contributions concerning the state-of-the-art in: advanced and novel acceleration techniques; sophisticated physics at the frontier of FELs; and the underlying and enabling techniques of high brightness electron beam physics. Interdisciplinary research connecting two or more of these fields is also increasingly represented, as exemplified by entirely new concepts such as plasma based electron beam sources, and coherent imaging with fs-class electron beams. We hope that in producing this special edition of Journal of Physics B: Atomic, Molecular and Optical Physics (iopscience.iop.org/0953-4075/) we may help further a challenging mission and ongoing intellectual adventure: the harnessing of newly emergent, compact advanced accelerators to the creation of new, agile light sources with unprecedented capabilities. New schemes for compact accelerators: laser- and beam-driven plasma accelerators; dielectric laser accelerators; THz accelerators. Latest results for compact accelerators. Target design and staging of advanced accelerators. Advanced injection and phase space manipulation techniques. Novel diagnostics: single-shot measurement of sub-fs bunch duration; measurement of ultra-low emittance. Generation and characterization of incoherent radiation: betatron and undulator radiation; Thomson/Compton scattering sources, novel THz sources. Generation and characterization of coherent radiation. Novel FEL simulation techniques. Advances in simulations of novel accelerators: simulations of injection and acceleration processes; simulations of coherent and incoherent radiation sources; start-to-end simulations of fifth generation light sources. Novel undulator schemes. Novel laser drivers for laser-driven accelerators: high-repetition rate laser systems; high wall-plug efficiency systems. Applications of compact accelerators: imaging; radiography; medical applications; electron diffraction and microscopy. Please submit your article by 15 May 2014 (expected web publication: winter 2014); submissions received after this date will be considered for the journal, but may not be included in the special issue.

Peptide self-assembly: thermodynamics and kinetics.

PubMed

Wang, Juan; Liu, Kai; Xing, Ruirui; Yan, Xuehai

2016-10-21

Self-assembling systems play a significant role in physiological functions and have therefore attracted tremendous attention due to their great potential for applications in energy, biomedicine and nanotechnology. Peptides, consisting of amino acids, are among the most popular building blocks and programmable molecular motifs. Nanostructures and materials assembled using peptides exhibit important potential for green-life new technology and biomedical applications mostly because of their bio-friendliness and reversibility. The formation of these ordered nanostructures pertains to the synergistic effect of various intermolecular non-covalent interactions, including hydrogen-bonding, π-π stacking, electrostatic, hydrophobic, and van der Waals interactions. Therefore, the self-assembly process is mainly driven by thermodynamics; however, kinetics is also a critical factor in structural modulation and function integration. In this review, we focus on the influence of thermodynamic and kinetic factors on structural assembly and regulation based on different types of peptide building blocks, including aromatic dipeptides, amphiphilic peptides, polypeptides, and amyloid-relevant peptides.

Pulsed Magnetic Field Driven Gas Core Reactors for Space Power & Propulsion Applications

NASA Technical Reports Server (NTRS)

Anghaie, Samim; Smith, Blair; Knight, Travis; Butler, Carey

2003-01-01

The present results indicated that: 1. A pulsed magnetic driven fission power concept, PMD-GCR is developed for closed (NER) and semi-open (NTR) operations. 2. In power mode, power is generated at alpha less than 1 for power levels of hundreds of KW or higher 3. IN semi open NTR mode, PMD-GCR generates thrust at I(sub sp) approx. 5,000 s and jet power approx. 5KW/Kg. 4. PMD-GCR is highly subcritical and is actively driven to critically. 5. Parallel path with fusion R&D needs in many areas including magnet and plasma.

Electrostatic quadrupole focused particle accelerating assembly with laminar flow beam

DOEpatents

Maschke, A.W.

1984-04-16

A charged particle accelerating assembly provided with a predetermined ratio of parametric structural characteristics and with related operating voltages applied to each of its linearly spaced focusing and accelerating quadrupoles, thereby to maintain a particle beam traversing the electrostatic fields of the quadrupoles in the assembly in an essentially laminar flow through the assembly.

Electrostatic quadrupole focused particle accelerating assembly with laminar flow beam

DOEpatents

Maschke, Alfred W.

1985-01-01

A charged particle accelerating assembly provided with a predetermined ratio of parametric structural characteristics and with related operating voltages applied to each of its linearly spaced focusing and accelerating quadrupoles, thereby to maintain a particle beam traversing the electrostatic fields of the quadrupoles in the assembly in an essentially laminar flow throughout the assembly.

ZPR-3 Assembly 11 : A cylindrical sssembly of highly enriched uranium and depleted uranium with an average {sup 235}U enrichment of 12 atom % and a depleted uranium reflector.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lell, R. M.; McKnight, R. D.; Tsiboulia, A.

2010-09-30

Over a period of 30 years, more than a hundred Zero Power Reactor (ZPR) critical assemblies were constructed at Argonne National Laboratory. The ZPR facilities, ZPR-3, ZPR-6, ZPR-9 and ZPPR, were all fast critical assembly facilities. The ZPR critical assemblies were constructed to support fast reactor development, but data from some of these assemblies are also well suited for nuclear data validation and to form the basis for criticality safety benchmarks. A number of the Argonne ZPR/ZPPR critical assemblies have been evaluated as ICSBEP and IRPhEP benchmarks. Of the three classes of ZPR assemblies, engineering mockups, engineering benchmarks and physicsmore » benchmarks, the last group tends to be most useful for criticality safety. Because physics benchmarks were designed to test fast reactor physics data and methods, they were as simple as possible in geometry and composition. The principal fissile species was {sup 235}U or {sup 239}Pu. Fuel enrichments ranged from 9% to 95%. Often there were only one or two main core diluent materials, such as aluminum, graphite, iron, sodium or stainless steel. The cores were reflected (and insulated from room return effects) by one or two layers of materials such as depleted uranium, lead or stainless steel. Despite their more complex nature, a small number of assemblies from the other two classes would make useful criticality safety benchmarks because they have features related to criticality safety issues, such as reflection by soil-like material. ZPR-3 Assembly 11 (ZPR-3/11) was designed as a fast reactor physics benchmark experiment with an average core {sup 235}U enrichment of approximately 12 at.% and a depleted uranium reflector. Approximately 79.7% of the total fissions in this assembly occur above 100 keV, approximately 20.3% occur below 100 keV, and essentially none below 0.625 eV - thus the classification as a 'fast' assembly. This assembly is Fast Reactor Benchmark No. 8 in the Cross Section Evaluation Working Group (CSEWG) Benchmark Specificationsa and has historically been used as a data validation benchmark assembly. Loading of ZPR-3 Assembly 11 began in early January 1958, and the Assembly 11 program ended in late January 1958. The core consisted of highly enriched uranium (HEU) plates and depleted uranium plates loaded into stainless steel drawers, which were inserted into the central square stainless steel tubes of a 31 x 31 matrix on a split table machine. The core unit cell consisted of two columns of 0.125 in.-wide (3.175 mm) HEU plates, six columns of 0.125 in.-wide (3.175 mm) depleted uranium plates and one column of 1.0 in.-wide (25.4 mm) depleted uranium plates. The length of each column was 10 in. (254.0 mm) in each half of the core. The axial blanket consisted of 12 in. (304.8 mm) of depleted uranium behind the core. The thickness of the depleted uranium radial blanket was approximately 14 in. (355.6 mm), and the length of the radial blanket in each half of the matrix was 22 in. (558.8 mm). The assembly geometry approximated a right circular cylinder as closely as the square matrix tubes allowed. According to the logbook and loading records for ZPR-3/11, the reference critical configuration was loading 10 which was critical on January 21, 1958. Subsequent loadings were very similar but less clean for criticality because there were modifications made to accommodate reactor physics measurements other than criticality. Accordingly, ZPR-3/11 loading 10 was selected as the only configuration for this benchmark. As documented below, it was determined to be acceptable as a criticality safety benchmark experiment. A very accurate transformation to a simplified model is needed to make any ZPR assembly a practical criticality-safety benchmark. There is simply too much geometric detail in an exact (as-built) model of a ZPR assembly, even a clean core such as ZPR-3/11 loading 10. The transformation must reduce the detail to a practical level without masking any of the important features of the critical experiment. And it must do this without increasing the total uncertainty far beyond that of the original experiment. Such a transformation is described in Section 3. It was obtained using a pair of continuous-energy Monte Carlo calculations. First, the critical configuration was modeled in full detail - every plate, drawer, matrix tube, and air gap was modeled explicitly. Then the regionwise compositions and volumes from the detailed as-built model were used to construct a homogeneous, two-dimensional (RZ) model of ZPR-3/11 that conserved the mass of each nuclide and volume of each region. The simple cylindrical model is the criticality-safety benchmark model. The difference in the calculated k{sub eff} values between the as-built three-dimensional model and the homogeneous two-dimensional benchmark model was used to adjust the measured excess reactivity of ZPR-3/11 loading 10 to obtain the k{sub eff} for the benchmark model.« less

The fabrication of integrated carbon pipes with sub-micron diameters

NASA Astrophysics Data System (ADS)

Kim, B. M.; Murray, T.; Bau, H. H.

2005-08-01

A method for fabricating integrated carbon pipes (nanopipettes) of sub-micron diameters and tens of microns in length is demonstrated. The carbon pipes are formed from a template consisting of the tip of a pulled alumino-silicate glass capillary coated with carbon deposited from a vapour phase. This method renders carbon nanopipettes without the need for ex situ assembly and facilitates parallel production of multiple carbon-pipe devices. An electric-field-driven transfer of ions in a KCl solution through the integrated carbon pipes exhibits nonlinear current-voltage (I-V) curves, markedly different from the Ohmic I-V curves observed in glass pipettes under similar conditions. The filling of the nanopipette with fluorescent suspension is also demonstrated.

Mechanistic basis of otolith formation during teleost inner ear development

PubMed Central

Wu, David; Freund, Jonathan B.; Fraser, Scott E.; Vermot, Julien

2011-01-01

Otoliths, which are connected to stereociliary bundles in the inner ear, serve as inertial sensors for balance. In teleostei, otolith development is critically dependant on flow forces generated by beating cilia; however, the mechanism by which flow controls otolith formation remains unclear. Here, we have developed a non-invasive flow probe using optical tweezers and a viscous flow model in order to demonstrate how the observed hydrodynamics influence otolith assembly. We show that rotational flow stirs and suppresses precursor agglomeration in the core of the cilia-driven vortex. The velocity field correlates with the shape of the otolith and we provide evidence that hydrodynamics is actively involved in controlling otolith morphogenesis. An implication of this hydrodynamic effect is that otolith self-assembly is mediated by the balance between Brownian motion and cilia-driven flow. More generally, this flow feature highlights an alternative biological strategy for controlling particle localization in solution. PMID:21316594

Onset of turbulence in accelerated high-Reynolds-number flow

NASA Astrophysics Data System (ADS)

Zhou, Ye; Robey, Harry F.; Buckingham, Alfred C.

2003-05-01

A new criterion, flow drive time, is identified here as a necessary condition for transition to turbulence in accelerated, unsteady flows. Compressible, high-Reynolds-number flows initiated, for example, in shock tubes, supersonic wind tunnels with practical limitations on dimensions or reservoir capacity, and high energy density pulsed laser target vaporization experimental facilities may not provide flow duration adequate for turbulence development. In addition, for critical periods of the overall flow development, the driving background flow is often unsteady in the experiments as well as in the physical flow situations they are designed to mimic. In these situations transition to fully developed turbulence may not be realized despite achievement of flow Reynolds numbers associated with or exceeding stationary flow transitional criteria. Basically our transitional criterion and prediction procedure extends to accelerated, unsteady background flow situations the remarkably universal mixing transition criterion proposed by Dimotakis [P. E. Dimotakis, J. Fluid Mech. 409, 69 (2000)] for stationary flows. This provides a basis for the requisite space and time scaling. The emphasis here is placed on variable density flow instabilities initiated by constant acceleration Rayleigh-Taylor instability (RTI) or impulsive (shock) acceleration Richtmyer-Meshkov instability (RMI) or combinations of both. The significant influences of compressibility on these developing transitional flows are discussed with their implications on the procedural model development. A fresh perspective for predictive modeling and design of experiments for the instability growth and turbulent mixing transitional interval is provided using an analogy between the well-established buoyancy-drag model with applications of a hierarchy of single point turbulent transport closure models. Experimental comparisons with the procedural results are presented where use is made of three distinctly different types of acceleration driven instability experiments: (1) classical, relatively low speed, constant acceleration RTI experiments; (2) shock tube, shockwave driven RMI flow mixing experiments; (3) laser target vaporization RTI and RMI mixing experiments driven at very high energy density. These last named experiments are of special interest as they provide scaleable flow conditions simulating those of astrophysical magnitude such as shock-driven hydrodynamic mixing in supernova evolution research.

Overview and Recent Accomplishments of Advanced Mirror Technology Development Phase 2 (AMTD-2)

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2015-01-01

AMTD uses a science-driven systems engineering approach to define & execute a long-term strategy to mature technologies necessary to enable future large aperture space telescopes. Because we cannot predict the future, we are pursuing multiple technology paths including monolithic & segmented mirrors. Assembled outstanding team from academia, industry & government; experts in science & space telescope engineering. Derived engineering specifications from science measurement needs & implementation constraints. Maturing 6 critical technologies required to enable 4 to 8 meter UVOIR space telescope mirror assemblies for both general astrophysics & ultra-high contrast exoplanet imaging. AMTD achieving all its goals & accomplishing all its milestones.

Quasistationary magnetic field generation with a laser-driven capacitor-coil assembly.

PubMed

Tikhonchuk, V T; Bailly-Grandvaux, M; Santos, J J; Poyé, A

2017-08-01

Recent experiments are showing possibilities to generate strong magnetic fields on the excess of 500 T with high-energy nanosecond laser pulses in a compact setup of a capacitor connected to a single turn coil. Hot electrons ejected from the capacitor plate (cathode) are collected at the other plate (anode), thus providing the source of a current in the coil. However, the physical processes leading to generation of currents exceeding hundreds of kiloamperes in such a laser-driven diode are not sufficiently understood. Here we present a critical analysis of previous results and propose a self-consistent model for the high current generation in a laser-driven capacitor-coil assembly. It accounts for three major effects controlling the diode current: the space charge neutralization, the plasma magnetization between the capacitor plates, and the Ohmic heating of the external circuit-the coil-shaped connecting wire. The model provides the conditions necessary for transporting strongly super-Alfvenic currents through the diode on the time scale of a few nanoseconds. The model validity is confirmed by a comparison with the available experimental data.

Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe–S Assembly Complex

PubMed Central

Fox, Nicholas G.; Das, Deepika; Chakrabarti, Mrinmoy; Lindahl, Paul A.; Barondeau, David P.

2015-01-01

Iron–sulfur (Fe–S) clusters function as protein cofactors for a wide variety of critical cellular reactions. In human mitochondria, a core Fe–S assembly complex [called SDUF and composed of NFS1, ISD11, ISCU2, and frataxin (FXN) proteins] synthesizes Fe–S clusters from iron, cysteine sulfur, and reducing equivalents and then transfers these intact clusters to target proteins. In vitro assays have relied on reducing the complexity of this complicated Fe–S assembly process by using surrogate electron donor molecules and monitoring simplified reactions. Recent studies have concluded that FXN promotes the synthesis of [4Fe-4S] clusters on the mammalian Fe–S assembly complex. Here the kinetics of Fe–S synthesis reactions were determined using different electron donation systems and by monitoring the products with circular dichroism and absorbance spectroscopies. We discovered that common surrogate electron donor molecules intercepted Fe–S cluster intermediates and formed high-molecular weight species (HMWS). The HMWS are associated with iron, sulfide, and thiol-containing proteins and have properties of a heterogeneous solubilized mineral with spectroscopic properties remarkably reminiscent of those of [4Fe-4S] clusters. In contrast, reactions using physiological reagents revealed that FXN accelerates the formation of [2Fe-2S] clusters rather than [4Fe-4S] clusters as previously reported. In the preceding paper [Fox, N. G., et al. (2015) Biochemistry 54, DOI: 10.1021/bi5014485], [2Fe-2S] intermediates on the SDUF complex were shown to readily transfer to uncomplexed ISCU2 or apo acceptor proteins, depending on the reaction conditions. Our results indicate that FXN accelerates a rate-limiting sulfur transfer step in the synthesis of [2Fe-2S] clusters on the human Fe–S assembly complex. PMID:26016518

Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex.

PubMed

Fox, Nicholas G; Das, Deepika; Chakrabarti, Mrinmoy; Lindahl, Paul A; Barondeau, David P

2015-06-30

Iron-sulfur (Fe-S) clusters function as protein cofactors for a wide variety of critical cellular reactions. In human mitochondria, a core Fe-S assembly complex [called SDUF and composed of NFS1, ISD11, ISCU2, and frataxin (FXN) proteins] synthesizes Fe-S clusters from iron, cysteine sulfur, and reducing equivalents and then transfers these intact clusters to target proteins. In vitro assays have relied on reducing the complexity of this complicated Fe-S assembly process by using surrogate electron donor molecules and monitoring simplified reactions. Recent studies have concluded that FXN promotes the synthesis of [4Fe-4S] clusters on the mammalian Fe-S assembly complex. Here the kinetics of Fe-S synthesis reactions were determined using different electron donation systems and by monitoring the products with circular dichroism and absorbance spectroscopies. We discovered that common surrogate electron donor molecules intercepted Fe-S cluster intermediates and formed high-molecular weight species (HMWS). The HMWS are associated with iron, sulfide, and thiol-containing proteins and have properties of a heterogeneous solubilized mineral with spectroscopic properties remarkably reminiscent of those of [4Fe-4S] clusters. In contrast, reactions using physiological reagents revealed that FXN accelerates the formation of [2Fe-2S] clusters rather than [4Fe-4S] clusters as previously reported. In the preceding paper [Fox, N. G., et al. (2015) Biochemistry 54, DOI: 10.1021/bi5014485], [2Fe-2S] intermediates on the SDUF complex were shown to readily transfer to uncomplexed ISCU2 or apo acceptor proteins, depending on the reaction conditions. Our results indicate that FXN accelerates a rate-limiting sulfur transfer step in the synthesis of [2Fe-2S] clusters on the human Fe-S assembly complex.

Evaluation of ENDF/B-IV and Hansen--Roach /sup 233/U cross sections for use in criticality calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

McNeany, S.R.; Jenkins, J.D.

Eleven /sup 233/U solution critical assemblies spanning an H//sup 233/U ratio range of 40 to 2000 and an unreflected metal /sup 233/U assembly were calculated with ENDF/B-IV and Hansen--Roach cross sections. Results from these calculations are compared with the experimental results and with each other. An increasing disagreement is observed between calculations with ENDF/B and Hansen--Roach data with decreasing H//sup 233/U ratio, indicative of large differences in their intermediate-energy cross sections. The Hansen--Roach cross sections appeared to give reasonably good agreement with experiments over the whole range, whereas the ENDF/B calculations yielded high values for k/sub eff/ on assemblies ofmore » low moderation. It is concluded that serious problems exist in the ENDF/B-IV representation of the /sup 233/U cross sections in the intermediate energy range and that further evaluation of this nuclide is warranted. In addition, it is recommended that an experimental program be undertaken to obtain /sup 233/U criticality data at low H//sup 233/U ratios for verification of generalized criticality safety guidelines. 3 figures, 15 tables.« less

Initial condition of stochastic self-assembly

NASA Astrophysics Data System (ADS)

Davis, Jason K.; Sindi, Suzanne S.

2016-02-01

The formation of a stable protein aggregate is regarded as the rate limiting step in the establishment of prion diseases. In these systems, once aggregates reach a critical size the growth process accelerates and thus the waiting time until the appearance of the first critically sized aggregate is a key determinant of disease onset. In addition to prion diseases, aggregation and nucleation is a central step of many physical, chemical, and biological process. Previous studies have examined the first-arrival time at a critical nucleus size during homogeneous self-assembly under the assumption that at time t =0 the system was in the all-monomer state. However, in order to compare to in vivo biological experiments where protein constituents inherited by a newly born cell likely contain intermediate aggregates, other possibilities must be considered. We consider one such possibility by conditioning the unique ergodic size distribution on subcritical aggregate sizes; this least-informed distribution is then used as an initial condition. We make the claim that this initial condition carries fewer assumptions than an all-monomer one and verify that it can yield significantly different averaged waiting times relative to the all-monomer condition under various models of assembly.

Unitaxial constant velocity microactuator

DOEpatents

McIntyre, Timothy J.

1994-01-01

A uniaxial drive system or microactuator capable of operating in an ultra-high vacuum environment. The mechanism includes a flexible coupling having a bore therethrough, and two clamp/pusher assemblies mounted in axial ends of the coupling. The clamp/pusher assemblies are energized by voltage-operated piezoelectrics therewithin to operatively engage the shaft and coupling causing the shaft to move along its rotational axis through the bore. The microactuator is capable of repeatably positioning to sub-manometer accuracy while affording a scan range in excess of 5 centimeters. Moreover, the microactuator generates smooth, constant velocity motion profiles while producing a drive thrust of greater than 10 pounds. The system is remotely controlled and piezoelectrically driven, hence minimal thermal loading, vibrational excitation, or outgassing is introduced to the operating environment.

The PHOTOSYNTHESIS AFFECTED MUTANT68–LIKE Protein Evolved from a PSII Assembly Factor to Mediate Assembly of the Chloroplast NAD(P)H Dehydrogenase Complex in Arabidopsis[W

PubMed Central

Armbruster, Ute; Rühle, Thilo; Kreller, Renate; Strotbek, Christoph; Zühlke, Jessica; Tadini, Luca; Blunder, Thomas; Hertle, Alexander P.; Qi, Yafei; Rengstl, Birgit; Nickelsen, Jörg; Frank, Wolfgang; Leister, Dario

2013-01-01

In vascular plants, the chloroplast NAD(P)H dehydrogenase complex (NDH-C) is assembled from five distinct subcomplexes, the membrane-spanning (subM) and the luminal (subL) subcomplexes, as well as subA, subB, and subE. The assembly process itself is poorly understood. Vascular plant genomes code for two related intrinsic thylakoid proteins, PHOTOSYNTHESIS-AFFECTED MUTANT68 (PAM68), a photosystem II assembly factor, and PHOTOSYNTHESIS-AFFECTED MUTANT68-LIKE (PAM68L). As we show here, inactivation of Arabidopsis thaliana PAM68L in the pam68l-1 mutant identifies PAM68L as an NDH-C assembly factor. The mutant lacks functional NDH holocomplexes and accumulates three distinct NDH-C assembly intermediates (subB, subM, and subA+L), which are also found in mutants defective in subB assembly (ndf5) or subM expression (CHLORORESPIRATORY REDUCTION4-3 mutant). NDH-C assembly in the cyanobacterium Synechocystis sp PCC 6803 and the moss Physcomitrella patens does not require PAM68 proteins, as demonstrated by the analysis of knockout lines for the single-copy PAM68 genes in these species. We conclude that PAM68L mediates the attachment of subB- and subM-containing intermediates to a complex that contains subA and subL. The evolutionary appearance of subL and PAM68L during the transition from mosses like P. patens to flowering plants suggests that the associated increase in the complexity of the NDH-C might have been facilitated by the recruitment of evolutionarily novel assembly factors like PAM68L. PMID:24096342

Anisotropic k-essence cosmologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chimento, Luis P.; Forte, Monica

We investigate a Bianchi type-I cosmology with k-essence and find the set of models which dissipate the initial anisotropy. There are cosmological models with extended tachyon fields and k-essence having a constant barotropic index. We obtain the conditions leading to a regular bounce of the average geometry and the residual anisotropy on the bounce. For constant potential, we develop purely kinetic k-essence models which are dust dominated in their early stages, dissipate the initial anisotropy, and end in a stable de Sitter accelerated expansion scenario. We show that linear k-field and polynomial kinetic function models evolve asymptotically to Friedmann-Robertson-Walker cosmologies.more » The linear case is compatible with an asymptotic potential interpolating between V{sub l}{proportional_to}{phi}{sup -{gamma}{sub l}}, in the shear dominated regime, and V{sub l}{proportional_to}{phi}{sup -2} at late time. In the polynomial case, the general solution contains cosmological models with an oscillatory average geometry. For linear k-essence, we find the general solution in the Bianchi type-I cosmology when the k field is driven by an inverse square potential. This model shares the same geometry as a quintessence field driven by an exponential potential.« less

Autonomous Assembly of Modular Structures in Space and on Extraterrestrial Locations

NASA Astrophysics Data System (ADS)

Alhorn, Dean C.

2005-02-01

The new U.S. National Vision for Space Exploration requires many new enabling technologies to accomplish the goals of space commercialization and returning humans to the moon and extraterrestrial environments. Traditionally, flight elements are complete sub-systems requiring humans to complete the integration and assembly. These bulky structures also require the use of heavy launch vehicles to send the units to a desired location. This philosophy necessitates a high degree of safety, numerous space walks at a significant cost. Future space mission costs must be reduced and safety increased to reasonably achieve exploration goals. One proposed concept is the autonomous assembly of space structures. This concept is an affordable, reliable solution to in-space and extraterrestrial assembly. Assembly is autonomously performed when two components join after determining that specifications are correct. Local sensors continue monitor joint integrity post assembly, which is critical for safety and structural reliability. Achieving this concept requires a change in space structure design philosophy and the development of innovative technologies to perform autonomous assembly. Assembly of large space structures will require significant numbers of integrity sensors. Thus simple, low-cost sensors are integral to the success of this concept. This paper addresses these issues and proposes a novel concept for assembling space structures autonomously. Core technologies required to achieve in space assembly are presented. These core technologies are critical to the goal of utilizing space in a cost efficient and safe manner. Additionally, these novel technologies can be applied to other systems both on earth and extraterrestrial environments.

S/sub n/ analysis of the TRX metal lattices with ENDF/B version III data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wheeler, F.J.; Pearlstein, S.

1975-03-01

Two critical assemblies, designated as thermal-reactor benchmarks TRX-1 and TRX-2 for ENDF/B data testing, were analyzed using the one-dimensional S/sub n/-theory code SCAMP. The two assemblies were simple lattices of aluminum-clad, uranium-metal fuel rods in triangular arrays with D$sub 2$O as moderator and reflector. The fuel was low-enriched (1.3 percent $sup 235$U), 0.387-inch in diameter and had an active height of 48 inches. The volume ratio of water to uranium was 2.35 for the TRX-1 lattice and 4.02 for TRX-2. Full-core S/sub n/ calculations based on Version III data were performed for these assemblies and the results obtained were comparedmore » with the measured values of the multiplication factors, the ratio of epithermal-to-thermal neutron capture in $sup 238$U, the ratio of epithermal-to-thermal fission in $sup 235$U, the ratio of $sup 238$U fission to $sup 235$U fission, and the ratio of capture in $sup 238$U to fission in $sup 235$U. Reaction rates were obtained from a central region of the full- core problems. Multigroup cross sections for the reactor calculation were obtained from S/sub n/ cell calculations with resonance self-shielding calculated using the RABBLE treatment. The results of the analyses are generally consistent with results obtained by other investigators. (auth)« less

Electrostatic Wave Generation and Transverse Ion Acceleration by Alfvenic Wave Components of BBELF Turbulence

NASA Technical Reports Server (NTRS)

Singh, Nagendra; Khazanov, George; Mukhter, Ali

2007-01-01

We present results here from 2.5-D particle-in-cell simulations showing that the electrostatic (ES) components of broadband extremely low frequency (BBELF) waves could possibly be generated by cross-field plasma instabilities driven by the relative drifts between the heavy and light ion species in the electromagnetic (EM) Alfvenic component of the BBELF waves in a multi-ion plasma. The ES components consist of ion cyclotron as well as lower hybrid modes. We also demonstrate that the ES wave generation is directly involved in the transverse acceleration of ions (TAI) as commonly measured with the BBELF wave events. The heating is affected by ion cyclotron resonance in the cyclotron modes and Landau resonance in the lower hybrid waves. In the simulation we drive the plasma by the transverse electric field, E(sub y), of the EM waves; the frequency of E(sub y), omega(sub d), is varied from a frequency below the heavy ion cyclotron frequency, OMEGA(sub h), to below the light ion cyclotron frequency, OMEGA(sub i). We have also performed simulations for E(sub y) having a continuous spectrum given by a power law, namely, |Ey| approx. omega(sub d) (exp -alpha), where the exponent alpha = _, 1, and 2 in three different simulations. The driving electric field generates polarization and ExB drifts of the ions and electrons. When the interspecies relative drifts are sufficiently large, they drive electrostatic waves, which cause perpendicular heating of both light and heavy ions. The transverse ion heating found here is discussed in relation to observations from Cluster, FAST and Freja.

Laser-free RF-gun as a combined source of THz and ps-sub-ps X-rays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agustsson, R.; Boucher, S.; Finn, O.

A coherent, mm-sub-mm-wave source driven by a RF electron gun is proposed for wide research applications as well as auxiliary inspection and screening, safe imaging, cancer diagnostics, surface defectoscopy, and enhanced time-domain spectroscopy. It allows generation of high peak and average THz-sub-THz radiation power provided by beam pre-bunching and chirping in the RF gun followed by microbunching in magnetic compressor, and resonant Cherenkov radiation of an essentially flat beam in a robust, ~inch-long, planar, mm-sub-mm gap structure. The proof-of-principle has been successfully demonstrated in Phase I on a 5 MeV beam of L-band thermionic injector of Idaho Accelerator Center. Themore » system can also deliver an intense, ps-sub-ps bursts of low-to-moderate dose of relativistic electrons and X-ray radiation produced by the same beam required for pulsed radiolysis as well as to enhance screening efficiency, throughput and safety.« less

Laser-free RF-gun as a combined source of THz and ps-sub-ps X-rays

DOE PAGES

Agustsson, R.; Boucher, S.; Finn, O.; ...

2015-01-01

A coherent, mm-sub-mm-wave source driven by a RF electron gun is proposed for wide research applications as well as auxiliary inspection and screening, safe imaging, cancer diagnostics, surface defectoscopy, and enhanced time-domain spectroscopy. It allows generation of high peak and average THz-sub-THz radiation power provided by beam pre-bunching and chirping in the RF gun followed by microbunching in magnetic compressor, and resonant Cherenkov radiation of an essentially flat beam in a robust, ~inch-long, planar, mm-sub-mm gap structure. The proof-of-principle has been successfully demonstrated in Phase I on a 5 MeV beam of L-band thermionic injector of Idaho Accelerator Center. Themore » system can also deliver an intense, ps-sub-ps bursts of low-to-moderate dose of relativistic electrons and X-ray radiation produced by the same beam required for pulsed radiolysis as well as to enhance screening efficiency, throughput and safety.« less

Namib Desert edaphic bacterial, fungal and archaeal communities assemble through deterministic processes but are influenced by different abiotic parameters.

PubMed

Johnson, Riegardt M; Ramond, Jean-Baptiste; Gunnigle, Eoin; Seely, Mary; Cowan, Don A

2017-03-01

The central Namib Desert is hyperarid, where limited plant growth ensures that biogeochemical processes are largely driven by microbial populations. Recent research has shown that niche partitioning is critically involved in the assembly of Namib Desert edaphic communities. However, these studies have mainly focussed on the Domain Bacteria. Using microbial community fingerprinting, we compared the assembly of the bacterial, fungal and archaeal populations of microbial communities across nine soil niches from four Namib Desert soil habitats (riverbed, dune, gravel plain and salt pan). Permutational multivariate analysis of variance indicated that the nine soil niches presented significantly different physicochemistries (R 2  = 0.8306, P ≤ 0.0001) and that bacterial, fungal and archaeal populations were soil niche specific (R 2  ≥ 0.64, P ≤ 0.001). However, the abiotic drivers of community structure were Domain-specific (P < 0.05), with P, clay and sand fraction, and NH 4 influencing bacterial, fungal and archaeal communities, respectively. Soil physicochemistry and soil niche explained over 50% of the variation in community structure, and communities displayed strong non-random patterns of co-occurrence. Taken together, these results demonstrate that in central Namib Desert soil microbial communities, assembly is principally driven by deterministic processes.

A plasma deflagration accelerator as a platform for laboratory astrophysics

NASA Astrophysics Data System (ADS)

Underwood, Thomas C.; Loebner, Keith T. K.; Cappelli, Mark A.

2017-06-01

The replication of astrophysical flows in the laboratory is critical for isolating particular phenomena and dynamics that appear in complex, highly-coupled natural systems. In particular, plasma jets are observed in astrophysical contexts at a variety of scales, typically at high magnetic Reynolds number and driven by internal currents. In this paper, we present detailed measurements of the plasma parameters within deflagration-produced plasma jets, the scaling of these parameters against both machine operating conditions and the corresponding astrophysical phenomena. Using optical and spectroscopic diagnostics, including Schlieren cinematography, we demonstrate the production of current-driven plasma jets of ∼100 km/s and magnetic Reynolds numbers of ∼100, and discuss the dynamics of their acceleration into vacuum. The results of this study will contribute to the reproduction of various types of astrophysical jets in the laboratory and indicate the ability to further probe active research areas such as jet collimation, stability, and interaction.

Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly.

PubMed

Romier, Christophe; James, Nicole; Birck, Catherine; Cavarelli, Jean; Vivarès, Christian; Collart, Martine A; Moras, Dino

2007-05-18

General transcription factor TFIID plays an essential role in transcription initiation by RNA polymerase II at numerous promoters. However, understanding of the assembly and a full structural characterization of this large 15 subunit complex is lacking. TFIID subunit TAF(II)5 has been shown to be present twice in this complex and to be critical for the function and assembly of TFIID. Especially, the TAF(II)5 N-terminal domain is required for its incorporation within TFIID and immuno-labelling experiments carried out by electron microscopy at low resolution have suggested that this domain might homodimerize, possibly explaining the three-lobed architecture of TFIID. However, the resolution at which the electron microscopy (EM) analyses were conducted is not sufficient to determine whether homodimerization occurs or whether a more intricate assembly implying other subunits is required. Here we report the X-ray structures of the fully evolutionary conserved C-terminal sub-domain of the TAF(II)5 N terminus, from yeast and the mammalian parasite Encephalitozoon cuniculi. This sub-domain displays a novel fold with specific surfaces having conserved physico-chemical properties that can form protein-protein interactions. Although a crystallographic dimer implying one of these surfaces is present in one of the crystal forms, several biochemical analyses show that this sub-domain is monomeric in solution, even at various salt conditions and in presence of different divalent cations. Consequently, the N-terminal sub-domain of the TAF(II)5 N terminus, which is homologous to a dimerization motif but has not been fully conserved during evolution, was studied by analytical ultracentrifugation and yeast genetics. Our results show that this sub-domain dimerizes at very high concentration but is neither required for yeast viability, nor for incorporation of two TAF(II)5 molecules within TFIID and for the assembly of this complex. Altogether, although our results do not argue in favour of a homodimerization of the TAF(II)5 N-terminal domain, our structural analyses suggest a role for this domain in assembly of TFIID and its related complexes SAGA, STAGA, TFTC and PCAF.

Studying astrophysical particle acceleration with laser-driven plasmas

NASA Astrophysics Data System (ADS)

Fiuza, Frederico

2016-10-01

The acceleration of non-thermal particles in plasmas is critical for our understanding of explosive astrophysical phenomena, from solar flares to gamma ray bursts. Particle acceleration is thought to be mediated by collisionless shocks and magnetic reconnection. The microphysics underlying these processes and their ability to efficiently convert flow and magnetic energy into non-thermal particles, however, is not yet fully understood. By performing for the first time ab initio 3D particle-in-cell simulations of the interaction of both magnetized and unmagnetized laser-driven plasmas, it is now possible to identify the optimal parameters for the study of particle acceleration in the laboratory relevant to astrophysical scenarios. It is predicted for the Omega and NIF laser conditions that significant non-thermal acceleration can occur during magnetic reconnection of laser-driven magnetized plasmas. Electrons are accelerated by the electric field near the X-points and trapped in contracting magnetic islands. This leads to a power-law tail extending to nearly a hundred times the thermal energy of the plasma and that contains a large fraction of the magnetic energy. The study of unmagnetized interpenetrating plasmas also reveals the possibility of forming collisionless shocks mediated by the Weibel instability on NIF. Under such conditions, both electrons and ions can be energized by scattering out of the Weibel-mediated turbulence. This also leads to power-law spectra that can be detected experimentally. The resulting experimental requirements to probe the microphysics of plasma particle acceleration will be discussed, paving the way for the first experiments of these important processes in the laboratory. As a result of these simulations and theoretical analysis, there are new experiments being planned on the Omega, NIF, and LCLS laser facilities to test these theoretical predictions. This work was supported by the SLAC LDRD program and DOE Office of Science, Fusion Energy Science (FWP 100182).

Microbubbles and Microparticles are Not Faithful Tracers of Turbulent Acceleration

NASA Astrophysics Data System (ADS)

Mathai, Varghese; Calzavarini, Enrico; Brons, Jon; Sun, Chao; Lohse, Detlef

2016-07-01

We report on the Lagrangian statistics of acceleration of small (sub-Kolmogorov) bubbles and tracer particles with Stokes number St ≪1 in turbulent flow. At a decreasing Reynolds number, the bubble accelerations show deviations from that of tracer particles; i.e., they deviate from the Heisenberg-Yaglom prediction and show a quicker decorrelation despite their small size and minute St. Using direct numerical simulations, we show that these effects arise due the drift of these particles through the turbulent flow. We theoretically predict this gravity-driven effect for developed isotropic turbulence, with the ratio of Stokes to Froude number or equivalently the particle drift velocity governing the enhancement of acceleration variance and the reductions in correlation time and intermittency. Our predictions are in good agreement with experimental and numerical results. The present findings are relevant to a range of scenarios encompassing tiny bubbles and droplets that drift through the turbulent oceans and the atmosphere. They also question the common usage of microbubbles and microdroplets as tracers in turbulence research.

Structure Design Approach and Technology Selection for Next Generation European Launchers

NASA Astrophysics Data System (ADS)

Baiocco, P.; Ramusat, G.; Kauffmann, J.; Jaredson, D.; Bouilly, Th.; Lavelle, F.; Louaas, E.

2012-07-01

In the framework of the next generation launchers activity at ESA, a top-down and a bottom-up approach has been performed for the alternative conception and promising technologies of NGL sub-assemblies and sub-systems. The top-down approach consisted in looking for system-driven design solutions and the bottom-up in the proposal of design solutions taking to substantial advantages for the system. The main investigations have been focused on structures and technologies tight to structures and interfaces. Specifications coming from a preliminary system design have been used in order to permit sub-system design with the goal to find the major advantage for the overall launch system. In this respect selection criteria have been identified and among these a specific evaluation of the payload mass over recurring cost advantage has been evaluated. The development cost, recurring cost and operational aspects have been considered as competitiveness factors for the identification of the most interesting solutions. The TRL/IRL has been assessed and a preliminary development plan has been identified. This approach is dedicated to reference NGL architectures, but alternative architectures have been investigated in order to assess their interest in terms of competitiveness factors and study of other technologies. This paper deals mainly with metallic and composite structures owing to sub-systems or sub-assemblies proposed for the NGL. The major sub-systems and structures analysed are the engine thrust frame (ETF), inter stage structures (ISS), cryogenic propellant tanks, feeding lines and attachments, pressurisation systems and fairing. The paper provides an overview of the main results of this investigation and the potential benefit it can provide.

Direct longitudinal laser acceleration of electrons in free space

NASA Astrophysics Data System (ADS)

Carbajo, Sergio; Nanni, Emilio A.; Wong, Liang Jie; Moriena, Gustavo; Keathley, Phillip D.; Laurent, Guillaume; Miller, R. J. Dwayne; Kärtner, Franz X.

2016-02-01

Compact laser-driven accelerators are pursued heavily worldwide because they make novel methods and tools invented at national laboratories widely accessible in science, health, security, and technology [V. Malka et al., Principles and applications of compact laser-plasma accelerators, Nat. Phys. 4, 447 (2008)]. Current leading laser-based accelerator technologies [S. P. D. Mangles et al., Monoenergetic beams of relativistic electrons from intense laser-plasma interactions, Nature (London) 431, 535 (2004); T. Toncian et al., Ultrafast laser-driven microlens to focus and energy-select mega-electron volt protons, Science 312, 410 (2006); S. Tokita et al. Single-shot ultrafast electron diffraction with a laser-accelerated sub-MeV electron pulse, Appl. Phys. Lett. 95, 111911 (2009)] rely on a medium to assist the light to particle energy transfer. The medium imposes material limitations or may introduce inhomogeneous fields [J. R. Dwyer et al., Femtosecond electron diffraction: "Making the molecular movie,", Phil. Trans. R. Soc. A 364, 741 (2006)]. The advent of few cycle ultraintense radially polarized lasers [S. Carbajo et al., Efficient generation of ultraintense few-cycle radially polarized laser pulses, Opt. Lett. 39, 2487 (2014)] has ushered in a novel accelerator concept [L. J. Wong and F. X. Kärtner, Direct acceleration of an electron in infinite vacuum by a pulsed radially polarized laser beam, Opt. Express 18, 25035 (2010); F. Pierre-Louis et al. Direct-field electron acceleration with ultrafast radially polarized laser beams: Scaling laws and optimization, J. Phys. B 43, 025401 (2010); Y. I. Salamin, Electron acceleration from rest in vacuum by an axicon Gaussian laser beam, Phys. Rev. A 73, 043402 (2006); C. Varin and M. Piché, Relativistic attosecond electron pulses from a free-space laser-acceleration scheme, Phys. Rev. E 74, 045602 (2006); A. Sell and F. X. Kärtner, Attosecond electron bunches accelerated and compressed by radially polarized laser pulses and soft-x-ray pulses from optical undulators, J. Phys. B 47, 015601 (2014)] avoiding the need of a medium or guiding structure entirely to achieve strong longitudinal energy transfer. Here we present the first observation of direct longitudinal laser acceleration of nonrelativistic electrons that undergo highly directional multi-GeV /m accelerating gradients. This demonstration opens a new frontier for direct laser-driven particle acceleration capable of creating well collimated and relativistic attosecond electron bunches [C. Varin and M. Piché, Relativistic attosecond electron pulses from a free-space laser-acceleration scheme, Phys. Rev. E 74, 045602 (2006)] and x-ray pulses [A. Sell and F. X. Kärtner, Attosecond electron bunches accelerated and compressed by radially polarized laser pulses and soft-x-ray pulses from optical undulators, J. Phys. B 47, 015601 (2014)].

Accelerating Corporate Research in the Development, Application and Deployment of Human Language Technologies

DTIC Science & Technology

2003-01-01

dubbed UIMA . At the heart of UIMA are powerful search capabilities and a data-driven framework for the development, composition and distributed...example, to Processing Resources in the GATE archi- tecture (Cunningham et al., 2000). In UIMA , a TAE is a recursive structure which may be composed of sub...closer look at the analysis engine framework . UIMA specifies an interface for an analysis engine; roughly speaking it is “CAS in” and “CAS out

Coassembly of Lysozyme and Amphiphilic Biomolecules Driven by Unimer-Aggregate Equilibrium.

PubMed

Tao, Yuanyuan; Ma, Xiaoteng; Cai, Yaqian; Liu, Li; Zhao, Hanying

2018-04-12

Synthesis and self-assembly of bioconjugates composed of proteins and synthetic molecules have been widely studied because of the potential applications in medicine, biotechnology, and nanotechnology. One of the challenging research studies in this area is to develop organic solvent-free approaches to the synthesis and self-assembly of amphiphilic bioconjugates. In this research, dialysis-assisted approach, a method based on unimer-aggregate equilibrium, was applied in the coassembly of lysozyme and conjugate of cholesterol and glutathione (Ch-GSH). In phosphate buffer solution, amphiphilic Ch-GSH conjugate self-assembles into vesicles, and the vesicle solution is dialyzed against lysozyme solution. Negatively charged Ch-GSH unimers produced in the unimer-vesicle exchange equilibrium, diffuse across the dialysis membrane and have electrostatic interaction with positively charged lysozyme, resulting in the formation of Ch-GSH-lysozyme bioconjugate. Above a critical concentration, the three-component bioconjugate molecules self-assemble into bioactive vesicles.

Fuel cell drives for road vehicles

NASA Astrophysics Data System (ADS)

Charnah, R. M.

For fuel-cell driven vehicles, including buses, the fuel cell may be the main, determining factor in the system but must be integrated into the complete design process. A Low-Floor Bus design is used to illustrate this point. The influence of advances in drive-train electronics is illustrated as are novel designs for motors and mechanical transmission of power to the wheels allowing the use of novel hub assemblies. A hybrid electric power system is being deployed in which Fuel Cells produce the energy needs but are coupled with batteries especially for acceleration phases and for recuperative braking.

Texturing of high T(sub c) superconducting polycrystalline fibers/wires by laser-driven directional solidification in an thermal gradient

NASA Technical Reports Server (NTRS)

Varshney, Usha; Eichelberger, B. Davis, III

1995-01-01

This paper summarizes the technique of laser-driven directional solidification in a controlled thermal gradient of yttria stabilized zirconia core coated Y-Ba-Cu-O materials to produce textured high T(sub c) superconducting polycrystalline fibers/wires with improved critical current densities in the extended range of magnetic fields at temperatures greater than 77 K. The approach involves laser heating to minimize phase segregation by heating very rapidly through the two-phase incongruent melt region to the single phase melt region and directionally solidifying in a controlled thermal gradient to achieve highly textured grains in the fiber axis direction. The technique offers a higher grain growth rate and a lower thermal budget compared with a conventional thermal gradient and is amenable as a continuous process for improving the J(sub c) of high T(sub c) superconducting polycrystalline fibers/wires. The technique has the advantage of suppressing weak-link behavior by orientation of crystals, formation of dense structures with enhanced connectivity, formation of fewer and cleaner grain boundaries, and minimization of phase segregation in the incongruent melt region.

The Coronal Analysis of SHocks and Waves (CASHeW) framework

NASA Astrophysics Data System (ADS)

Kozarev, Kamen A.; Davey, Alisdair; Kendrick, Alexander; Hammer, Michael; Keith, Celeste

2017-11-01

Coronal bright fronts (CBF) are large-scale wavelike disturbances in the solar corona, related to solar eruptions. They are observed (mostly in extreme ultraviolet (EUV) light) as transient bright fronts of finite width, propagating away from the eruption source location. Recent studies of individual solar eruptive events have used EUV observations of CBFs and metric radio type II burst observations to show the intimate connection between waves in the low corona and coronal mass ejection (CME)-driven shocks. EUV imaging with the atmospheric imaging assembly instrument on the solar dynamics observatory has proven particularly useful for detecting large-scale short-lived CBFs, which, combined with radio and in situ observations, holds great promise for early CME-driven shock characterization capability. This characterization can further be automated, and related to models of particle acceleration to produce estimates of particle fluxes in the corona and in the near Earth environment early in events. We present a framework for the coronal analysis of shocks and waves (CASHeW). It combines analysis of NASA Heliophysics System Observatory data products and relevant data-driven models, into an automated system for the characterization of off-limb coronal waves and shocks and the evaluation of their capability to accelerate solar energetic particles (SEPs). The system utilizes EUV observations and models written in the interactive data language. In addition, it leverages analysis tools from the SolarSoft package of libraries, as well as third party libraries. We have tested the CASHeW framework on a representative list of coronal bright front events. Here we present its features, as well as initial results. With this framework, we hope to contribute to the overall understanding of coronal shock waves, their importance for energetic particle acceleration, as well as to the better ability to forecast SEP events fluxes.

Overview and Recent Accomplishments of Advanced Mirror Technology Development (AMTD) for Very Large Space Telescopes

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2013-01-01

AMTD uses a science-driven systems engineering approach to define & execute a long-term strategy to mature technologies necessary to enable future large aperture space telescopes. Because we cannot predict the future, we are pursuing multiple technology paths including monolithic & segmented mirrors. Assembled outstanding team from academia, industry & government; experts in science & space telescope engineering. Derived engineering specifications from science measurement needs & implementation constraints. Maturing 6 critical technologies required to enable 4 to 8 meter UVOIR space telescope mirror assemblies for both general astrophysics & ultra-high contrast exoplanet imaging. AMTD achieving all its goals & accomplishing all its milestones.

Cytoskeletal motor-driven active self-assembly in in vitro systems

DOE PAGES

Lam, A. T.; VanDelinder, V.; Kabir, A. M. R.; ...

2015-11-11

Molecular motor-driven self-assembly has been an active area of soft matter research for the past decade. Because molecular motors transform chemical energy into mechanical work, systems which employ molecular motors to drive self-assembly processes are able to overcome kinetic and thermodynamic limits on assembly time, size, complexity, and structure. Here, we review the progress in elucidating and demonstrating the rules and capabilities of motor-driven active self-assembly. Lastly, we focus on the types of structures created and the degree of control realized over these structures, and discuss the next steps necessary to achieve the full potential of this assembly mode whichmore » complements robotic manipulation and passive self-assembly.« less

Time-dependent Electron Acceleration in Pulsar Wind Termination Shocks: Application to the 2011 April Crab Nebula Gamma-Ray Flare

NASA Astrophysics Data System (ADS)

Kroon, John J.; Becker, Peter A.; Finke, Justin D.

2018-01-01

The γ-ray flares from the Crab Nebula observed by AGILE and Fermi-LAT between 2007 and 2013 reached GeV photon energies and lasted several days. The strongest emission, observed during the 2011 April “superflare”, exceeded the quiescent level by more than an order of magnitude. These observations challenge the standard models for particle acceleration in pulsar wind nebulae, because the radiating electrons have energies exceeding the classical radiation-reaction limit for synchrotron emission. Particle-in-cell simulations have suggested that the classical synchrotron limit can be exceeded if the electrons also experience electrostatic acceleration due to shock-driven magnetic reconnection. In this paper, we revisit the problem using an analytic approach based on solving a fully time-dependent electron transport equation describing the electrostatic acceleration, synchrotron losses, and escape experienced by electrons in a magnetically confined plasma “blob” as it encounters and passes through the pulsar wind termination shock. We show that our model can reproduce the γ-ray spectra observed during the rising and decaying phases of each of the two sub-flare components of the 2011 April superflare. We integrate the spectrum for photon energies ≥slant 100 MeV to obtain the light curve for the event, which also agrees with the observations. We find that strong electrostatic acceleration occurs on both sides of the termination shock, driven by magnetic reconnection. We also find that the dominant mode of particle escape changes from diffusive escape to advective escape as the blob passes through the shock.

Systems analysis of a low-acceleration research facility

NASA Technical Reports Server (NTRS)

Martin, Gary L.; Ferebee, Melvin J., Jr.; Wright, Robert L.

1988-01-01

The Low-Acceleration Research Facility (LARF), an unmanned free-flier that is boosted from low-earth orbit to a desired altitude using an orbital transfer vehicle is discussed. Design techniques used to minimize acceleration-causing disturbances and to create an ultra-quiet workshop are discussed, focusing on residual acceleration induced by the environment, the spacecraft and experiments. The selection and integration of critical subsystems, such as electrical power and thermal control, that enable the LARf to accomodate sub-microgravity levels for extended periods of time are presented, including a discussion of the Low-Acceleration Module, which will supply the payload with 25.0 kW of power, and up to 11.8 kW in the low-power mode. Also, the data management, communications, guidance, navigation and control, and structural features of supporting subsystems are examined.

Measurement of the Infinite Multiplication Constant of Natural Uranium--Graphite Lattices in the RB-1 Critical Assembly by Means of the Zero Reactivity Method. MISURA DELLA COSTANTE DI MOLTIPLICAZIONE INFINITA DI RETICOLI A URANIO NATURALE E GRAFITE NELL'INSIEME CRITICO RB-1 CON IL METODO DELLA REATTIVITA' NULLA (in Italian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghillardotti, G.

1966-07-01

To reduce uncertainties to the minimum, measurements in the RB-1 were conducted on the same materials and with the same instrumentation as those used previously in MARIUS. The values measured in the RB-1, compared with the already known substitution data, are as follows: (a) the difference between the multiplication and the absorption intensity; (b) the fine structure of the flux in the cell; (c) the Pu/U index. The infinite mutiplication factor K{sub infinity} is obtained by combining measurements (a) and (b). The results of this research can be summed up as follows: 1. A consistent and complete experimental procedure hasmore » been devised for measuring the K{sub infinity} of natural uranium/graphite lattices by means of the zero reactivity method. The same applies to the procedure for analysis of the experimental data. 2. The error in (K{sub infinity} -- 1) inherent in the measurement can in our opinion be reduced to 2%. This limit was reached in the last experiment on lattices consisting of tubular elements. 3. Agreement proved to be good with the results obtained by the CEA in the critical assembly MARIUS. (auth)« less

Modal Analysis of MARS Solar Panel and Planar Vibrations

NASA Technical Reports Server (NTRS)

Simonyan, Andranik; Williams, R. Brett

2007-01-01

This slide presentation reviews the modal analysis of MARS solar panels and the planar vibrations. Included are views of the solar panels mock-up assembly, a view of the test seup,a view of the plot from the test, with the raw numbers of the frequencies in Hz values with the mode number, the spatial acceleration plots of Center sub panel at resonant frequencies, predictions from the Finite element models, an explanation of the two test that were done on the plate and the results from both tests,

An assessment of coupling algorithms for nuclear reactor core physics simulations

DOE PAGES

Hamilton, Steven; Berrill, Mark; Clarno, Kevin; ...

2016-04-01

This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Furthermore, numerical simulations demonstrating the efficiency ofmore » JFNK and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less

An assessment of coupling algorithms for nuclear reactor core physics simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hamilton, Steven; Berrill, Mark; Clarno, Kevin

This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Furthermore, numerical simulations demonstrating the efficiency ofmore » JFNK and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less

An assessment of coupling algorithms for nuclear reactor core physics simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hamilton, Steven, E-mail: hamiltonsp@ornl.gov; Berrill, Mark, E-mail: berrillma@ornl.gov; Clarno, Kevin, E-mail: clarnokt@ornl.gov

This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Numerical simulations demonstrating the efficiency of JFNKmore » and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less

C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation.

PubMed

Li, Chuang; Peng, Qiongfang; Wan, Xiao; Sun, Haili; Tang, Jun

2017-10-15

Promyelocytic leukemia protein (PML) nuclear bodies (NBs), which are sub-nuclear protein structures, are involved in a variety of important cellular functions. PML-NBs are assembled by PML isoforms, and contact between small ubiquitin-like modifiers (SUMOs) with the SUMO interaction motif (SIM) are critically involved in this process. PML isoforms contain a common N-terminal region and a variable C-terminus. However, the contribution of the C-terminal regions to PML-NB formation remains poorly defined. Here, using high-resolution microscopy, we show that mutation of the SIM distinctively influences the structure of NBs formed by each individual PML isoform, with that of PML-III and PML-V minimally changed, and PML-I and PML-IV dramatically impaired. We further identify several C-terminal elements that are important in regulating NB structure and provide strong evidence to suggest that the 8b element in PML-IV possesses a strong ability to interact with SUMO-1 and SUMO-2, and critically participates in NB formation. Our findings highlight the importance of PML C-termini in NB assembly and function, and provide molecular insight into the PML-NB assembly of each distinctive isoform. © 2017. Published by The Company of Biologists Ltd.

A mechanically driven form of Kirigami as a route to 3D mesostructures in micro/nanomembranes.

PubMed

Zhang, Yihui; Yan, Zheng; Nan, Kewang; Xiao, Dongqing; Liu, Yuhao; Luan, Haiwen; Fu, Haoran; Wang, Xizhu; Yang, Qinglin; Wang, Jiechen; Ren, Wen; Si, Hongzhi; Liu, Fei; Yang, Lihen; Li, Hejun; Wang, Juntong; Guo, Xuelin; Luo, Hongying; Wang, Liang; Huang, Yonggang; Rogers, John A

2015-09-22

Assembly of 3D micro/nanostructures in advanced functional materials has important implications across broad areas of technology. Existing approaches are compatible, however, only with narrow classes of materials and/or 3D geometries. This paper introduces ideas for a form of Kirigami that allows precise, mechanically driven assembly of 3D mesostructures of diverse materials from 2D micro/nanomembranes with strategically designed geometries and patterns of cuts. Theoretical and experimental studies demonstrate applicability of the methods across length scales from macro to nano, in materials ranging from monocrystalline silicon to plastic, with levels of topographical complexity that significantly exceed those that can be achieved using other approaches. A broad set of examples includes 3D silicon mesostructures and hybrid nanomembrane-nanoribbon systems, including heterogeneous combinations with polymers and metals, with critical dimensions that range from 100 nm to 30 mm. A 3D mechanically tunable optical transmission window provides an application example of this Kirigami process, enabled by theoretically guided design.

Context clues: the importance of stem cell-material interactions

PubMed Central

Murphy, William L.

2014-01-01

Understanding the processes by which stem cells give rise to de novo tissues is an active focus of stem cell biology and bioengineering disciplines. Instructive morphogenic cues surrounding the stem cell during morphogenesis create what is referred to as the stem cell microenvironment. An emerging paradigm in stem cell bioengineering involves “biologically driven assembly,” in which stem cells are encouraged to largely define their own morphogenesis processes. However, even in the case of biologically driven assembly, stem cells do not act alone. The properties of the surrounding microenvironment can be critical regulators of cell fate. Stem cell-material interactions are among the most well-characterized microenvironmental effectors of stem cell fate, and they establish a signaling “context” that can define the mode of influence for morphogenic cues. Here we describe illustrative examples of cell-material interactions that occur during in vitro stem cell studies, with an emphasis on how cell-material interactions create instructive contexts for stem cell differentiation and morphogenesis. PMID:24369691

A mechanically driven form of Kirigami as a route to 3D mesostructures in micro/nanomembranes

PubMed Central

Zhang, Yihui; Yan, Zheng; Nan, Kewang; Xiao, Dongqing; Liu, Yuhao; Luan, Haiwen; Fu, Haoran; Wang, Xizhu; Yang, Qinglin; Wang, Jiechen; Ren, Wen; Si, Hongzhi; Liu, Fei; Yang, Lihen; Li, Hejun; Wang, Juntong; Guo, Xuelin; Luo, Hongying; Wang, Liang; Huang, Yonggang; Rogers, John A.

2015-01-01

Assembly of 3D micro/nanostructures in advanced functional materials has important implications across broad areas of technology. Existing approaches are compatible, however, only with narrow classes of materials and/or 3D geometries. This paper introduces ideas for a form of Kirigami that allows precise, mechanically driven assembly of 3D mesostructures of diverse materials from 2D micro/nanomembranes with strategically designed geometries and patterns of cuts. Theoretical and experimental studies demonstrate applicability of the methods across length scales from macro to nano, in materials ranging from monocrystalline silicon to plastic, with levels of topographical complexity that significantly exceed those that can be achieved using other approaches. A broad set of examples includes 3D silicon mesostructures and hybrid nanomembrane–nanoribbon systems, including heterogeneous combinations with polymers and metals, with critical dimensions that range from 100 nm to 30 mm. A 3D mechanically tunable optical transmission window provides an application example of this Kirigami process, enabled by theoretically guided design. PMID:26372959

Experimental evidence of space charge driven resonances in high intensity linear accelerators

DOE PAGES

Jeon, Dong -O

2016-01-12

In the construction of high intensity accelerators, it is the utmost goal to minimize the beam loss by avoiding or minimizing contributions of various halo formation mechanisms. As a halo formation mechanism, space charge driven resonances are well known for circular accelerators. However, the recent finding showed that even in linear accelerators the space charge potential can excite the 4σ = 360° fourth order resonance [D. Jeon et al., Phys. Rev. ST Accel. Beams 12, 054204 (2009)]. This study increased the interests in space charge driven resonances of linear accelerators. Experimental studies of the space charge driven resonances of highmore » intensity linear accelerators are rare as opposed to the multitude of simulation studies. This paper presents an experimental evidence of the space charge driven 4σ ¼ 360° resonance and the 2σ x(y) – 2σ z = 0 resonance of a high intensity linear accelerator through beam profile measurements from multiple wire-scanners. Moreover, measured beam profiles agree well with the characteristics of the space charge driven 4σ = 360° resonance and the 2σ x(y) – 2σ z = 0 resonance that are predicted by the simulation.« less

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

NASA Astrophysics Data System (ADS)

Patel, Bhavesh H.; Percivalle, Claudia; Ritson, Dougal J.; Duffy, Colm D.; Sutherland, John D.

2015-04-01

A minimal cell can be thought of as comprising informational, compartment-forming and metabolic subsystems. To imagine the abiotic assembly of such an overall system, however, places great demands on hypothetical prebiotic chemistry. The perceived differences and incompatibilities between these subsystems have led to the widely held assumption that one or other subsystem must have preceded the others. Here we experimentally investigate the validity of this assumption by examining the assembly of various biomolecular building blocks from prebiotically plausible intermediates and one-carbon feedstock molecules. We show that precursors of ribonucleotides, amino acids and lipids can all be derived by the reductive homologation of hydrogen cyanide and some of its derivatives, and thus that all the cellular subsystems could have arisen simultaneously through common chemistry. The key reaction steps are driven by ultraviolet light, use hydrogen sulfide as the reductant and can be accelerated by Cu(I)-Cu(II) photoredox cycling.

Modeling Ultra-fast assembly and sintering of gold nanostructures

NASA Astrophysics Data System (ADS)

Lane, J. Matthew D.; Salerno, K. Michael; Grest, Gary S.; Fan, Hongyou

We use fully atomistic simulations to understand the role of extreme pressure in the assembly and sintering of fcc superlattices of alkanethiol-coated gold nanocrystals into larger nanostructures. Recent quasi-isentropic experiments have shown that 1D, 2D and 3D nanostructures can be formed and recovered from dynamic compression experiments on Sandia's Veloce pulsed power accelerator. Here, we describe the role of coating properties, such as ligand length and grafting density, on ligand migration and deformation processes during pressure-driven coalescence of metal nano cores into permanent nanowires, nanosheets and 3D structures. The role of uniaxial vs isotropic pressure and the effects of compression along various superlattice orientations will be discussed. Sandia National Laboratories is a multi-mission laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Won, Jong-Pil, E-mail: jpwon@konkuk.ac.kr; Hwang, Un-Jong; Lee, Su-Jin

This study evaluated the performance of shotcrete using high strength C{sub 12}A{sub 7} mineral-based accelerator that has been developed to improve the durability and long-term strength. Rebound, compressive strength and flexural strength were tested in the field. Test result showed that existing C{sub 12}A{sub 7} mineral-based accelerator exhibits better early strength than the high-strength C{sub 12}A{sub 7} mineral-based accelerator until the early age, but high-strength C{sub 12}A{sub 7} mineral-based accelerator shows about 29% higher at the long-term age of 28 days. Microstructural analysis such as scanning electron microscope (SEM), X-ray diffraction (XRD) and nitrogen adsorption method was evaluated to analyzemore » long-term strength development mechanism of high strength C{sub 12}A{sub 7} mineral-based accelerator. As analysis result, it had more dense structure due to the reaction product by adding material that used to enhanced strength. It had better resistance performance in chloride ion penetration, freezing–thawing and carbonation than shotcrete that used existing C{sub 12}A{sub 7} mineral-based accelerator.« less

Immature HIV-1 lattice assembly dynamics are regulated by scaffolding from nucleic acid and the plasma membrane

PubMed Central

Pak, Alexander J.; Grime, John M. A.; Sengupta, Prabuddha; Chen, Antony K.; Durumeric, Aleksander E. P.; Srivastava, Anand; Yeager, Mark; Briggs, John A. G.; Lippincott-Schwartz, Jennifer; Voth, Gregory A.

2017-01-01

The packaging and budding of Gag polyprotein and viral RNA is a critical step in the HIV-1 life cycle. High-resolution structures of the Gag polyprotein have revealed that the capsid (CA) and spacer peptide 1 (SP1) domains contain important interfaces for Gag self-assembly. However, the molecular details of the multimerization process, especially in the presence of RNA and the cell membrane, have remained unclear. In this work, we investigate the mechanisms that work in concert between the polyproteins, RNA, and membrane to promote immature lattice growth. We develop a coarse-grained (CG) computational model that is derived from subnanometer resolution structural data. Our simulations recapitulate contiguous and hexameric lattice assembly driven only by weak anisotropic attractions at the helical CA–SP1 junction. Importantly, analysis from CG and single-particle tracking photoactivated localization (spt-PALM) trajectories indicates that viral RNA and the membrane are critical constituents that actively promote Gag multimerization through scaffolding, while overexpression of short competitor RNA can suppress assembly. We also find that the CA amino-terminal domain imparts intrinsic curvature to the Gag lattice. As a consequence, immature lattice growth appears to be coupled to the dynamics of spontaneous membrane deformation. Our findings elucidate a simple network of interactions that regulate the early stages of HIV-1 assembly and budding. PMID:29114055

Observation of Betatron X-Ray Radiation in a Self-Modulated Laser Wakefield Accelerator Driven with Picosecond Laser Pulses

DOE PAGES

Albert, F.; Lemos, N.; Shaw, J. L.; ...

2017-03-31

We investigate a new regime for betatron x-ray emission that utilizes kilojoule-class picosecond lasers to drive wakes in plasmas. When such laser pulses with intensities of ~ 5 × 1 0 18 W / cm 2 are focused into plasmas with electron densities of ~ 1 × 1 0 19 cm - 3 , they undergo self-modulation and channeling, which accelerates electrons up to 200 MeV energies and causes those electrons to emit x rays. The measured x-ray spectra are fit with a synchrotron spectrum with a critical energy of 10–20 keV, and 2D particle-in-cell simulations were used to modelmore » the acceleration and radiation of the electrons in our experimental conditions« less

Acceleration of boundary element method for linear elasticity

NASA Astrophysics Data System (ADS)

Zapletal, Jan; Merta, Michal; Čermák, Martin

2017-07-01

In this work we describe the accelerated assembly of system matrices for the boundary element method using the Intel Xeon Phi coprocessors. We present a model problem, provide a brief overview of its discretization and acceleration of the system matrices assembly using the coprocessors, and test the accelerated version using a numerical benchmark.

Overview of Heavy Ion Fusion Accelerator Research in the U. S.

NASA Astrophysics Data System (ADS)

Friedman, Alex

2002-12-01

This article provides an overview of current U.S. research on accelerators for Heavy Ion Fusion, that is, inertial fusion driven by intense beams of heavy ions with the goal of energy production. The concept, beam requirements, approach, and major issues are introduced. An overview of a number of new experiments is presented. These include: the High Current Experiment now underway at Lawrence Berkeley National Laboratory; studies of advanced injectors (and in particular an approach based on the merging of multiple beamlets), being investigated experimentally at Lawrence Livermore National Laboratory); the Neutralized (chamber) Transport Experiment being assembled at Lawrence Berkeley National Laboratory; and smaller experiments at the University of Maryland and at Princeton Plasma Physics Laboratory. The comprehensive program of beam simulations and theory is outlined. Finally, prospects and plans for further development of this promising approach to fusion energy are discussed.

MEMS-based, RF-driven, compact accelerators

NASA Astrophysics Data System (ADS)

Persaud, A.; Seidl, P. A.; Ji, Q.; Breinyn, I.; Waldron, W. L.; Schenkel, T.; Vinayakumar, K. B.; Ni, D.; Lal, A.

2017-10-01

Shrinking existing accelerators in size can reduce their cost by orders of magnitude. Furthermore, by using radio frequency (RF) technology and accelerating ions in several stages, the applied voltages can be kept low paving the way to new ion beam applications. We make use of the concept of a Multiple Electrostatic Quadrupole Array Linear Accelerator (MEQALAC) and have previously shown the implementation of its basic components using printed circuit boards, thereby reducing the size of earlier MEQALACs by an order of magnitude. We now demonstrate the combined integration of these components to form a basic accelerator structure, including an initial beam-matching section. In this presentation, we will discuss the results from the integrated multi-beam ion accelerator and also ion acceleration using RF voltages generated on-board. Furthermore, we will show results from Micro-Electro-Mechanical Systems (MEMS) fabricated focusing wafers, which can shrink the dimension of the system to the sub-mm regime and lead to cheaper fabrication. Based on these proof-of-concept results we outline a scaling path to high beam power for applications in plasma heating in magnetized target fusion and in neutral beam injectors for future Tokamaks. This work was supported by the Office of Science of the US Department of Energy through the ARPA-e ALPHA program under contracts DE-AC02-05CH11231.

Measuring and monitoring KIPT Neutron Source Facility Reactivity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cao, Yan; Gohar, Yousry; Zhong, Zhaopeng

2015-08-01

Argonne National Laboratory (ANL) of USA and Kharkov Institute of Physics and Technology (KIPT) of Ukraine have been collaborating on developing and constructing a neutron source facility at Kharkov, Ukraine. The facility consists of an accelerator-driven subcritical system. The accelerator has a 100 kW electron beam using 100 MeV electrons. The subcritical assembly has k eff less than 0.98. To ensure the safe operation of this neutron source facility, the reactivity of the subcritical core has to be accurately determined and continuously monitored. A technique which combines the area-ratio method and the flux-to-current ratio method is purposed to determine themore » reactivity of the KIPT subcritical assembly at various conditions. In particular, the area-ratio method can determine the absolute reactivity of the subcritical assembly in units of dollars by performing pulsed-neutron experiments. It provides reference reactivities for the flux-to-current ratio method to track and monitor the reactivity deviations from the reference state while the facility is at other operation modes. Monte Carlo simulations are performed to simulate both methods using the numerical model of the KIPT subcritical assembly. It is found that the reactivities obtained from both the area-ratio method and the flux-to-current ratio method are spatially dependent on the neutron detector locations and types. Numerical simulations also suggest optimal neutron detector locations to minimize the spatial effects in the flux-to-current ratio method. The spatial correction factors are calculated using Monte Carlo methods for both measuring methods at the selected neutron detector locations. Monte Carlo simulations are also performed to verify the accuracy of the flux-to-current ratio method in monitoring the reactivity swing during a fuel burnup cycle.« less

Winds of Massive Magnetic Stars: Interacting Fields and Flow

NASA Astrophysics Data System (ADS)

Daley-Yates, S.; Stevens, I. R.

2018-01-01

We present results of 3D numerical simulations of magnetically confined, radiatively driven stellar winds of massive stars, conducted using the astrophysical MHD code Pluto, with a focus on understanding the rotational variability of radio and sub-mm emission. Radiative driving is implemented according to the Castor, Abbott and Klein theory of radiatively driven winds. Many magnetic massive stars posses a magnetic axis which is inclined with respect to the rotational axis. This misalignment leads to a complex wind structure as magnetic confinement, centrifugal acceleration and radiative driving act to channel the circumstellar plasma into a warped disk whose observable properties should be apparent in multiple wavelengths. This structure is analysed to calculate free-free thermal radio emission and determine the characteristic intensity maps and radio light curves.

Stoichiometry and thickness dependence of superconducting properties of niobium nitride thin films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beebe, Melissa R., E-mail: mrbeebe@email.wm.edu; Beringer, Douglas B.; Burton, Matthew C.

2016-03-15

The current technology used in linear particle accelerators is based on superconducting radio frequency (SRF) cavities fabricated from bulk niobium (Nb), which have smaller surface resistance and therefore dissipate less energy than traditional nonsuperconducting copper cavities. Using bulk Nb for the cavities has several advantages, which are discussed elsewhere; however, such SRF cavities have a material-dependent accelerating gradient limit. In order to overcome this fundamental limit, a multilayered coating has been proposed using layers of insulating and superconducting material applied to the interior surface of the cavity. The key to this multilayered model is to use superconducting thin films tomore » exploit the potential field enhancement when these films are thinner than their London penetration depth. Such field enhancement has been demonstrated in MgB{sub 2} thin films; here, the authors consider films of another type-II superconductor, niobium nitride (NbN). The authors present their work correlating stoichiometry and superconducting properties in NbN thin films and discuss the thickness dependence of their superconducting properties, which is important for their potential use in the proposed multilayer structure. While there are some previous studies on the relationship between stoichiometry and critical temperature T{sub C}, the authors are the first to report on the correlation between stoichiometry and the lower critical field H{sub C1}.« less

Microbe-driven turnover offsets mineral-mediated storage of soil carbon under elevated CO2

Treesearch

Benjamin N. Sulman; Richard P. Phillips; A. Christopher Oishi; Elena Shevliakova; Stephen W. Pacala

2014-01-01

The sensitivity of soil organic carbon (SOC) to changing environmental conditions represents a critical uncertainty in coupled carbon cycle–climate models1.Much of this uncertainty arises from our limited understanding of the extent to which root–microbe interactions induce SOC losses (through accelerated decomposition or ‘priming’2) or indirectly promote SOC gains (...

Centrifugal acceleration of the polar wind

NASA Technical Reports Server (NTRS)

Horwitz, J. L.; Ho, C. W.; Scarbro, H. D.; Wilson, G. R.; Moore, T. E.

1994-01-01

The effect of parallel ion acceleration associated with convection was first applied to energization of test particle polar ions by Cladis (1986). However, this effect is typically neglected in 'self-consistent' models of polar plasma outflow, apart from the fluid simulation by Swift (1990). Here we include approximations for this acceleration, which we broadly characterize as centrifugal in nature, in our time-dependent, semikinetic model of polar plasma outflow and describe the effects on the bulk parameter profiles and distribution functions of H+ and O+. For meridional convection across the pole the approximate parallel force along a polar magnetic field line may be written as F(sub cent, pole) = 1.5m(E(sub i))/B(sub i))squared (r(squared)/r(sup 3)(sub i)) where m is ion mass, r is geometric distance; and E(sub i), B(sub i) and r(sub i) refer to the electric and magnetic field magnitudes and geocentric distance at the ionosphere, respectively. For purely longitudinal convection along a constant L shell the parallel force is F(cent. long) = F(sub cent, pole)(1 - (r/(r(sub i)L))(sup 3/2)/(1 - 3r/(4 r(sub i)L))(sup 5/2). For high latitudes the difference between these two cases is relatively unimportant below approximately 5 R(sub E). We find that the steady state O+ bulk velocities and parallel temperatures strongly increase and decrease, respectively, with convection strength. In particular, the bulk velocities increase from near 0 km/s at 4000 km altitude to approximately 10 km/s at 5 R(sub E) geocentric distance for 50-mV/m ionospheric convection electric field. However, the centrifugal effect on the steady O+ density profiles depends on the exobase ion and electron temperatures: for low-base temperatures (T(sub i) = T(sub e) = 3000 K) the O+ density at high altitudes increases greatly with convection, while for higher base temperatures (T(sub i) = 5000 K, T(sub e) = 9000 K), the high-altitude O+ density decreases somewhat as convection is enhanced. The centrifugal force further has a pronounced effect on the escaping O+ flux, especially for cool exobase conditions; as referenced to the 4000-km altitude, the steady state O+ flux increases from 10(exp 5) ions/sq cm/s when the ionospheric convection field E(sub i) = 0 mV/m to approximately 10(exp 7) ions/sq cm/s when E(sub i) = 100 mV/m. The centrifugal effect also decreases the time scale for approach to steady-state. For example, in the plasma expansion for T(sub i) = T(sub e) = 3000 K, the O+ density at 7 R(sub E) reaches only 10(exp -7) of it final value approximately 1.5 hours after expansion onset for E(sub i) = 0. For meridional convection driven by E(sub i) = 50 mV/m, the density at the same time after initial injection is 30-50% of its asymptotic level. The centrifugal acceleration described here is a possible explanation for the large (up to approximately 10 km/s or more) o+ outflow velocities observed in the midlatitude polar magnetosphere with the Dynamics Explorer 1 and Akebono spacecraft.

A compact linear accelerator based on a scalable microelectromechanical-system RF-structure

DOE PAGES

Persaud, A.; Ji, Q.; Feinberg, E.; ...

2017-06-08

Here, a new approach for a compact radio-frequency (RF) accelerator structure is presented. The new accelerator architecture is based on the Multiple Electrostatic Quadrupole Array Linear Accelerator (MEQALAC) structure that was first developed in the 1980s. The MEQALAC utilized RF resonators producing the accelerating fields and providing for higher beam currents through parallel beamlets focused using arrays of electrostatic quadrupoles (ESQs). While the early work obtained ESQs with lateral dimensions on the order of a few centimeters, using a printed circuit board (PCB), we reduce the characteristic dimension to the millimeter regime, while massively scaling up the potential number ofmore » parallel beamlets. Using Microelectromechanical systems scalable fabrication approaches, we are working on further red ucing the characteristic dimension to the sub-millimeter regime. The technology is based on RF-acceleration components and ESQs implemented in the PCB or silicon wafers where each beamlet passes through beam apertures in the wafer. The complete accelerator is then assembled by stacking these wafers. This approach has the potential for fast and inexpensive batch fabrication of the components and flexibility in system design for application specific beam energies and currents. For prototyping the accelerator architecture, the components have been fabricated using the PCB. In this paper, we present proof of concept results of the principal components using the PCB: RF acceleration and ESQ focusing. Finally, ongoing developments on implementing components in silicon and scaling of the accelerator technology to high currents and beam energies are discussed.« less

A compact linear accelerator based on a scalable microelectromechanical-system RF-structure

NASA Astrophysics Data System (ADS)

Persaud, A.; Ji, Q.; Feinberg, E.; Seidl, P. A.; Waldron, W. L.; Schenkel, T.; Lal, A.; Vinayakumar, K. B.; Ardanuc, S.; Hammer, D. A.

2017-06-01

A new approach for a compact radio-frequency (RF) accelerator structure is presented. The new accelerator architecture is based on the Multiple Electrostatic Quadrupole Array Linear Accelerator (MEQALAC) structure that was first developed in the 1980s. The MEQALAC utilized RF resonators producing the accelerating fields and providing for higher beam currents through parallel beamlets focused using arrays of electrostatic quadrupoles (ESQs). While the early work obtained ESQs with lateral dimensions on the order of a few centimeters, using a printed circuit board (PCB), we reduce the characteristic dimension to the millimeter regime, while massively scaling up the potential number of parallel beamlets. Using Microelectromechanical systems scalable fabrication approaches, we are working on further reducing the characteristic dimension to the sub-millimeter regime. The technology is based on RF-acceleration components and ESQs implemented in the PCB or silicon wafers where each beamlet passes through beam apertures in the wafer. The complete accelerator is then assembled by stacking these wafers. This approach has the potential for fast and inexpensive batch fabrication of the components and flexibility in system design for application specific beam energies and currents. For prototyping the accelerator architecture, the components have been fabricated using the PCB. In this paper, we present proof of concept results of the principal components using the PCB: RF acceleration and ESQ focusing. Ongoing developments on implementing components in silicon and scaling of the accelerator technology to high currents and beam energies are discussed.

A compact linear accelerator based on a scalable microelectromechanical-system RF-structure.

PubMed

Persaud, A; Ji, Q; Feinberg, E; Seidl, P A; Waldron, W L; Schenkel, T; Lal, A; Vinayakumar, K B; Ardanuc, S; Hammer, D A

2017-06-01

A new approach for a compact radio-frequency (RF) accelerator structure is presented. The new accelerator architecture is based on the Multiple Electrostatic Quadrupole Array Linear Accelerator (MEQALAC) structure that was first developed in the 1980s. The MEQALAC utilized RF resonators producing the accelerating fields and providing for higher beam currents through parallel beamlets focused using arrays of electrostatic quadrupoles (ESQs). While the early work obtained ESQs with lateral dimensions on the order of a few centimeters, using a printed circuit board (PCB), we reduce the characteristic dimension to the millimeter regime, while massively scaling up the potential number of parallel beamlets. Using Microelectromechanical systems scalable fabrication approaches, we are working on further reducing the characteristic dimension to the sub-millimeter regime. The technology is based on RF-acceleration components and ESQs implemented in the PCB or silicon wafers where each beamlet passes through beam apertures in the wafer. The complete accelerator is then assembled by stacking these wafers. This approach has the potential for fast and inexpensive batch fabrication of the components and flexibility in system design for application specific beam energies and currents. For prototyping the accelerator architecture, the components have been fabricated using the PCB. In this paper, we present proof of concept results of the principal components using the PCB: RF acceleration and ESQ focusing. Ongoing developments on implementing components in silicon and scaling of the accelerator technology to high currents and beam energies are discussed.

78 FR 59917 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary Sub...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... of Apparel Articles Assembled in Beneficiary Sub-Saharan African Countries From Regional and Third... quota-free treatment for certain textile and apparel articles imported from designated beneficiary sub... apparel articles wholly assembled in one or more beneficiary sub-Saharan African countries from fabric...

SPECTRAL PROPERTIES OF LARGE GRADUAL SOLAR ENERGETIC PARTICLE EVENTS. II. SYSTEMATIC Q/M DEPENDENCE OF HEAVY ION SPECTRAL BREAKS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Desai, M. I.; Dayeh, M. A.; Ebert, R. W.

2016-09-10

We fit ∼0.1–500 MeV nucleon{sup −1} H–Fe spectra in 46 large solar energetic particle (SEP) events with the double power-law Band function to obtain a normalization constant, low- and high-energy parameters γ {sub a} and γ {sub b}, and break energy E {sub B}, and derive the low-energy spectral slope γ {sub 1}. We find that: (1) γ {sub a}, γ {sub 1}, and γ {sub b} are species-independent and the spectra steepen with increasing energy; (2) E {sub B} decreases systematically with decreasing Q/M scaling as (Q/M){sup α}; (3) α varies between ∼0.2–3 and is well correlated with themore » ∼0.16–0.23 MeV nucleon{sup −1} Fe/O; (4) in most events, α < 1.4, γ {sub b}– γ {sub a} > 3, and O E {sub B} increases with γ {sub b}– γ {sub a}; and (5) in many extreme events (associated with faster coronal mass ejections (CMEs) and GLEs), Fe/O and {sup 3}He/{sup 4}He ratios are enriched, α ≥ 1.4, γ {sub b}– γ {sub a} < 3, and E {sub B} decreases with γ {sub b}– γ {sub a}. The species-independence of γ {sub a}, γ {sub 1}, and γ {sub b} and the Q/M dependence of E {sub B} within an event and the α values suggest that double power-law SEP spectra occur due to diffusive acceleration by near-Sun CME shocks rather than scattering in interplanetary turbulence. Using γ {sub 1}, we infer that the average compression ratio for 33 near-Sun CME shocks is 2.49 ± 0.08. In most events, the Q/M dependence of E {sub B} is consistent with the equal diffusion coefficient condition and the variability in α is driven by differences in the near-shock wave intensity spectra, which are flatter than the Kolmogorov turbulence spectrum but weaker than the spectra for extreme events. In contrast, in extreme events, enhanced wave power enables faster CME shocks to accelerate impulsive suprathermal ions more efficiently than ambient coronal ions.« less

Universal Fragment Descriptors for Predicting Electronic and Mechanical Properties of Inorganic Crystals

NASA Astrophysics Data System (ADS)

Oses, Corey; Isayev, Olexandr; Toher, Cormac; Curtarolo, Stefano; Tropsha, Alexander

Historically, materials discovery is driven by a laborious trial-and-error process. The growth of materials databases and emerging informatics approaches finally offer the opportunity to transform this practice into data- and knowledge-driven rational design-accelerating discovery of novel materials exhibiting desired properties. By using data from the AFLOW repository for high-throughput, ab-initio calculations, we have generated Quantitative Materials Structure-Property Relationship (QMSPR) models to predict critical materials properties, including the metal/insulator classification, band gap energy, and bulk modulus. The prediction accuracy obtained with these QMSPR models approaches training data for virtually any stoichiometric inorganic crystalline material. We attribute the success and universality of these models to the construction of new materials descriptors-referred to as the universal Property-Labeled Material Fragments (PLMF). This representation affords straightforward model interpretation in terms of simple heuristic design rules that could guide rational materials design. This proof-of-concept study demonstrates the power of materials informatics to dramatically accelerate the search for new materials.

The impact of plasma dynamics on the self-magnetic-pinch diode impedance

DOE PAGES

Bennett, Nichelle; Crain, M. Dale; Droemer, Darryl W.; ...

2015-03-20

In this study, the self-magnetic-pinch diode is being developed as an intense electron beam source for pulsed-power-driven x-ray radiography. The basic operation of this diode has long been understood in the context of pinched diodes, including the dynamic effect that the diode impedance decreases during the pulse due to electrode plasma formation and expansion. Experiments being conducted at Sandia National Laboratories' RITS-6 accelerator are helping to characterize these plasmas using time-resolved and time-integrated camera systems in the x-ray and visible. These diagnostics are analyzed in conjunction with particle-in-cell simulations of anode plasma formation and evolution. The results confirm the long-standingmore » theory of critical-current operation with the addition of a time-dependent anode-cathode gap length. Finally, the results may suggest that anomalous impedance collapse is driven by increased plasma radial drift, leading to larger-than-average ion v r × B θ acceleration into the gap.« less

Observation of 690 MV m -1 Electron Accelerating Gradient with a Laser-Driven Dielectric Microstructure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wootton, K. P.; Wu, Z.; Cowan, B. M.

Acceleration of electrons using laser-driven dielectric microstructures is a promising technology for the miniaturization of particle accelerators. In this work, experimental results are presented of relativistic electron acceleration with 690±100 MVm -1 gradient. This is a record-high accelerating gradient for a dielectric microstructure accelerator, nearly doubling the previous record gradient. To reach higher acceleration gradients the present experiment employs 90 fs duration laser pulses.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Tianfu; Ma, Zhuang; Li, Guoping

Electrostatic self-assembly in organic solvent without intensively oxidative or corrosive environments, was adopted to prepare Al/Fe{sub 2}O{sub 3}/MWCNT nanostructured energetic materials as an energy generating material. The negatively charged MWCNT was used as a glue-like agent to direct the self-assembly of the well dispersed positively charged Al (fuel) and Fe{sub 2}O{sub 3} (oxide) nanoparticles. This spontaneous assembly method without any surfactant chemistry or other chemical and biological moieties decreased the aggregation of the same nanoparticles largely, moreover, the poor interfacial contact between the Al (fuel) and Fe{sub 2}O{sub 3} (oxide) nanoparticles was improved significantly, which was the key characteristic ofmore » high performance nanostructured energetic materials. In addition, the assembly process was confirmed as Diffusion-Limited Aggregation. The assembled Al/Fe{sub 2}O{sub 3}/MWCNT nanostructured energetic materials showed excellent performance with heat release of 2400 J/g, peak pressure of 0.42 MPa and pressurization rate of 105.71 MPa/s, superior to that in the control group Al/Fe{sub 2}O{sub 3} nanostructured energetic materials prepared by sonication with heat release of 1326 J/g, peak pressure of 0.19 MPa and pressurization rate of 33.33 MPa/s. Therefore, the approach, which is facile, opens a promising route to the high performance nanostructured energetic materials. - Graphical abstract: The negatively charged MWCNT was used as a glue-like agent to direct the self-assembly of the well dispersed positively charged Al (fuel) and Fe{sub 2}O{sub 3} (oxide) nanoparticles. - Highlights: • A facile spontaneous electrostatic assembly strategy without surfactant was adopted. • The fuels and oxidizers assembled into densely packed nanostructured composites. • The assembled nanostructured energetic materials have excellent performance. • This high performance energetic material can be scaled up for practical application. • This strategy can be applied into other nanostructured energetic material systems.« less

Application of magnetically insulated transmission lines for high current, high voltage electron beam accelerators

NASA Astrophysics Data System (ADS)

Shope, S. L.; Mazarakis, M. G.; Frost, C. A.; Poukey, J. W.; Turman, B. N.

Self Magnetically Insulated Transmission Lines (MITL) adders were used successfully in a number of Sandia accelerators such as HELIA, HERMES III, and SABRE. Most recently we used at MITL adder in the RADLAC/SMILE electron beam accelerator to produce high quality, small radius (r(sub rho) less than 2 cm), 11 - 15 MeV, 50 - 100-kA beams with a small transverse velocity v(perpendicular)/c = beta(perpendicular) less than or equal to 0.1. In RADLAC/SMILE, a coaxial MITL passed through the eight, 2 MV vacuum envelopes. The MITL summed the voltages of all eight feeds to a single foilless diode. The experimental results are in good agreement with code simulations. Our success with the MITL technology led us to investigate the application to higher energy accelerator designs. We have a conceptual design for a cavity-fed MITL that sums the voltages from 100 identical, inductively-isolated cavities. Each cavity is a toroidal structure that is driven simultaneously by four 8-ohm pulse-forming lines, providing a 1-MV voltage pulse to each of the 100 cavities. The point design accelerator is 100 MV, 500 kA, with a 30 - 50 ns FWHM output pulse.

Finalizing the DTAG: Implementation and Testing of Design Improvements for Reliability and Availability

DTIC Science & Technology

2015-09-30

acoustics and fine scale motion. The success of the Dtag has resulted in an increased demand for the instrument from researchers both within the...sensor blocks sound when the animal is close to the surface. The polyethylene shell was eliminated in the Dtag-3 design to improve acoustic ...into 3 main sub-assemblies (Figure 5): 1) foam sub-assembly, 2) sensor sub-assembly, and 3) Electronics sub-assembly. This separation enables rapid

Advances in the computation of the Sjöstrand, Rossi, and Feynman distributions

DOE PAGES

Talamo, A.; Gohar, Y.; Gabrielli, F.; ...

2017-02-01

This study illustrates recent computational advances in the application of the Sjöstrand (area), Rossi, and Feynman methods to estimate the effective multiplication factor of a subcritical system driven by an external neutron source. The methodologies introduced in this study have been validated with the experimental results from the KUKA facility of Japan by Monte Carlo (MCNP6 and MCNPX) and deterministic (ERANOS, VARIANT, and PARTISN) codes. When the assembly is driven by a pulsed neutron source generated by a particle accelerator and delayed neutrons are at equilibrium, the Sjöstrand method becomes extremely fast if the integral of the reaction rate frommore » a single pulse is split into two parts. These two integrals distinguish between the neutron counts during and after the pulse period. To conclude, when the facility is driven by a spontaneous fission neutron source, the timestamps of the detector neutron counts can be obtained up to the nanosecond precision using MCNP6, which allows obtaining the Rossi and Feynman distributions.« less

A measurable Lawson criterion and hydro-equivalent curves for inertial confinement fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, C. D.; Betti, R.; Departments of Mechanical Engineering and Physics and Astronomy, University of Rochester, Rochester, New York 14623

2008-10-15

It is shown that the ignition condition (Lawson criterion) for inertial confinement fusion (ICF) can be cast in a form dependent on the only two parameters of the compressed fuel assembly that can be measured with existing techniques: the hot spot ion temperature (T{sub i}{sup h}) and the total areal density ({rho}R{sub tot}), which includes the cold shell contribution. A marginal ignition curve is derived in the {rho}R{sub tot}, T{sub i}{sup h} plane and current implosion experiments are compared with the ignition curve. On this plane, hydrodynamic equivalent curves show how a given implosion would perform with respect to themore » ignition condition when scaled up in the laser-driver energy. For 3<{sub n}<6 keV, an approximate form of the ignition condition (typical of laser-driven ICF) is {sub n}{sup 2.6}{center_dot}<{rho}R{sub tot}>{sub n}>50 keV{sup 2.6}{center_dot} g/cm{sup 2}, where <{rho}R{sub tot}>{sub n} and {sub n} are the burn-averaged total areal density and hot spot ion temperature, respectively. Both quantities are calculated without accounting for the alpha-particle energy deposition. Such a criterion can be used to determine how surrogate D{sub 2} and subignited DT target implosions perform with respect to the one-dimensional ignition threshold.« less

Accelerated Threshold Fatigue Crack Growth Effect-Powder Metallurgy Aluminum Alloy

NASA Technical Reports Server (NTRS)

Piascik, R. S.; Newman, J. A.

2002-01-01

Fatigue crack growth (FCG) research conducted in the near threshold regime has identified a room temperature creep crack growth damage mechanism for a fine grain powder metallurgy (PM) aluminum alloy (8009). At very low (Delta) K, an abrupt acceleration in room temperature FCG rate occurs at high stress ratio (R = K(sub min)/K(sub max)). The near threshold accelerated FCG rates are exacerbated by increased levels of K(sub max) (K(sub max) = 0.4 K(sub IC)). Detailed fractographic analysis correlates accelerated FCG with the formation of crack-tip process zone micro-void damage. Experimental results show that the near threshold and K(sub max) influenced accelerated crack growth is time and temperature dependent.

Data-driven Simulations of Magnetic Connectivity in Behind-the-Limb Gamma-ray Flares and Associated Coronal Mass Ejections

NASA Astrophysics Data System (ADS)

Jin, M.; Petrosian, V.; Liu, W.; Nitta, N.; Omodei, N.; Rubio da Costa, F.; Effenberger, F.; Li, G.; Pesce-Rollins, M.

2017-12-01

Recent Fermi detection of high-energy gamma-ray emission from the behind-the-limb (BTL) solar flares pose a puzzle on the particle acceleration and transport mechanisms in such events. Due to the large separation between the flare site and the location of gamma-ray emission, it is believed that the associated coronal mass ejections (CMEs) play an important role in accelerating and subsequently transporting particles back to the Sun to produce obseved gamma-rays. We explore this scenario by simulating the CME associated with a well-observed flare on 2014 September 1 about 40 degrees behind the east solar limb and by comparing the simulation and observational results. We utilize a data-driven global magnetohydrodynamics model (AWSoM: Alfven-wave Solar Model) to track the dynamical evolution of the global magnetic field during the event and investigate the magnetic connectivity between the CME/CME-driven shock and the Fermi emission region. Moreover, we derive the time-varying shock parameters (e.g., compression ratio, Alfven Mach number, and ThetaBN) over the area that is magnetically connected to the visible solar disk where Fermi gamma-ray emission originates. Our simulation shows that the visible solar disk develops connections both to the flare site and to the CME-driven shock during the eruption, which indicate that the CME's interaction with the global solar corona is critical for understanding such Fermi BTL events and gamma-ray flares in general. We discuss the causes and implications of Fermi BTL events, in the framework of a potential shift of paradigm on particle acceleration in solar flares/CMEs.

Stable generation of GeV-class electron beams from self-guided laser-plasma channels

NASA Astrophysics Data System (ADS)

Hafz, Nasr A. M.; Jeong, Tae Moon; Choi, Il Woo; Lee, Seong Ku; Pae, Ki Hong; Kulagin, Victor V.; Sung, Jae Hee; Yu, Tae Jun; Hong, Kyung-Han; Hosokai, Tomonao; Cary, John R.; Ko, Do-Kyeong; Lee, Jongmin

2008-09-01

Table-top laser-driven plasma accelerators are gaining attention for their potential use in miniaturizing future high-energy accelerators. By irradiating gas jet targets with ultrashort intense laser pulses, the generation of quasimonoenergetic electron beams was recently observed. Currently, the stability of beam generation and the ability to scale to higher electron beam energies are critical issues for practical laser acceleration. Here, we demonstrate the first generation of stable GeV-class electron beams from stable few-millimetre-long plasma channels in a self-guided wakefield acceleration process. As primary evidence of the laser wakefield acceleration in a bubble regime, we observed a boost of both the electron beam energy and quality by reducing the plasma density and increasing the plasma length in a 1-cm-long gas jet. Subsequent three-dimensional simulations show the possibility of achieving even higher electron beam energies by minimizing plasma bubble elongation, and we anticipate dramatic increases in beam energy and quality in the near future. This will pave the way towards ultracompact, all-optical electron beam accelerators and their applications in science, technology and medicine.

Conformal dip-coating of patterned surfaces for capillary die-to-substrate self-assembly

NASA Astrophysics Data System (ADS)

Mastrangeli, M.; Ruythooren, W.; Van Hoof, C.; Celis, J.-P.

2009-04-01

Capillarity-driven self-assembly of small chips onto planar target substrates is a promising alternative to robotic pick-and-place assembly. It critically relies on the selective deposition of thin fluid films on patterned binding sites, which is anyway normally non-conformal. We found that the addition of a thin wetting sidewall, surrounding the entire site perimeter, enables the conformal fluid coverage of arbitrarily shaped sites through dip-coating, significantly improves the reproducibility of the coating process and strongly reduces its sensitivity to surface defects. In this paper we support the feasibility and potential of this method by demonstrating the conformal dip-coating of square and triangular sites conditioned with combinations of different hydrophobic and hydrophilic surface chemistries. We present both experimental and simulative evidence of the advantages brought by the introduction of the wetting boundary on film coverage accuracy. Application of our surface preparation method to capillary self-assembly could result in higher precision in die-to-substrate registration and larger freedom in site shape design.

Katherine E. Weimer Award: X-ray light sources from laser-plasma and laser-electron interaction: development and applications

NASA Astrophysics Data System (ADS)

Albert, Felicie

2017-10-01

Bright sources of x-rays, such as synchrotrons and x-ray free electron lasers (XFEL) are transformational tools for many fields of science. They are used for biology, material science, medicine, or industry. Such sources rely on conventional particle accelerators, where electrons are accelerated to gigaelectronvolts (GeV) energies. The accelerated particles are wiggled in magnetic structures to emit x-ray radiation that is commonly used for molecular crystallography, fluorescence studies, chemical analysis, medical imaging, and many other applications. One of the drawbacks of these machines is their size and cost, because electric field gradients are limited to about 100 V/M in conventional accelerators. Particle acceleration in laser-driven plasmas is an alternative to generate x-rays via betatron emission, Compton scattering, or bremsstrahlung. A plasma can sustain electrical fields many orders of magnitude higher than that in conventional radiofrequency accelerator structures. When short, intense laser pulses are focused into a gas, it produces electron plasma waves in which electrons can be trapped and accelerated to GeV energies. X-ray sources, driven by electrons from laser-wakefield acceleration, have unique properties that are analogous to synchrotron radiation, with a 1000-fold shorter pulse. An important use of x-rays from laser plasma accelerators is in High Energy Density (HED) science, which requires laser and XFEL facilities to create in the laboratory extreme conditions of temperatures and pressures that are usually found in the interiors of stars and planets. To diagnose such extreme states of matter, the development of efficient, versatile and fast (sub-picosecond scale) x-ray probes has become essential. In these experiments, x-ray photons can pass through dense material, and absorption of the x-rays can be directly measured, via spectroscopy or imaging, to inform scientists about the temperature and density of the targets being studied. Performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344, supported by the LLNL LDRD program (16ERD024), and by the DOE Office Science Early Career Research Program (SCW1575).

Programmable DNA tile self-assembly using a hierarchical sub-tile strategy.

PubMed

Shi, Xiaolong; Lu, Wei; Wang, Zhiyu; Pan, Linqiang; Cui, Guangzhao; Xu, Jin; LaBean, Thomas H

2014-02-21

DNA tile based self-assembly provides a bottom-up approach to construct desired nanostructures. DNA tiles have been directly constructed from ssDNA and readily self-assembled into 2D lattices and 3D superstructures. However, for more complex lattice designs including algorithmic assemblies requiring larger tile sets, a more modular approach could prove useful. This paper reports a new DNA 'sub-tile' strategy to easily create whole families of programmable tiles. Here, we demonstrate the stability and flexibility of our sub-tile structures by constructing 3-, 4- and 6-arm DNA tiles that are subsequently assembled into 2D lattices and 3D nanotubes according to a hierarchical design. Assembly of sub-tiles, tiles, and superstructures was analyzed using polyacrylamide gel electrophoresis and atomic force microscopy. DNA tile self-assembly methods provide a bottom-up approach to create desired nanostructures; the sub-tile strategy adds a useful new layer to this technique. Complex units can be made from simple parts. The sub-tile approach enables the rapid redesign and prototyping of complex DNA tile sets and tiles with asymmetric designs.

Robustness of waves with a high phase velocity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tajima, T., E-mail: ttajima@uci.edu; Tri Alpha Energy, Inc., P.O. Box 7010, Rancho Santa Margarita, CA 92688; Necas, A., E-mail: anecas@trialphaenergy.com

Norman Rostoker pioneered research of (1) plasma-driven accelerators and (2) beam-driven fusion reactors. The collective acceleration, coined by Veksler, advocates to drive above-ionization plasma waves by an electron beam to accelerate ions. The research on this, among others, by the Rostoker group incubated the idea that eventually led to the birth of the laser wakefield acceleration (LWFA), by which a large and robust accelerating collective fields may be generated in plasma in which plasma remains robust and undisrupted. Besides the emergence of LWFA, the Rostoker research spawned our lessons learned on the importance of adiabatic acceleration of ions in collectivemore » accelerators, including the recent rebirth in laser-driven ion acceleration efforts in a smooth adiabatic fashion by a variety of ingenious methods. Following Rostoker’s research in (2), the beam-driven Field Reversed Configuration (FRC) has accomplished breakthroughs in recent years. The beam-driven kinetic plasma instabilities have been found to drive the reactivity of deuteron-deuteron fusion beyond the thermonuclear yield in C-2U plasma that Rostoker started. This remarkable result in FRCs as well as the above mentioned LWFA may be understood with the aid of the newly introduced idea of the “robustness hypothesis of waves with a high phase velocity”. It posits that when the wave driven by a particle beam (or laser pulse) has a high phase velocity, its amplitude is high without disrupting the supporting bulk plasma. This hypothesis may guide us into more robust and efficient fusion reactors and more compact accelerators.« less

Modeling dynamic plasmas driven by ultraintense nano-focused x-ray laser pulses in solid iron targets

NASA Astrophysics Data System (ADS)

Royle, Ryan; Sentoku, Yasuhiko; Mancini, Roberto

2017-10-01

The hard x-ray free electron laser has proven to be a valuable tool for high energy density (HED) physics as it is able to produce well-characterized samples of HED matter at exactly solid density and homogeneous temperatures. However, if the x-ray pulses are focused to sub-micron spot sizes, where peak intensities can exceed 1020 W/cm2, the plasmas driven by sources of non-thermal photoelectrons and Auger electrons can be highly dynamic and so cannot be modeled by atomic kinetics or fluid codes. We apply the 2D/3D particle-in-cell code, PICLS-which has been extended with numerous physics models to enable the simulation of XFEL-driven plasmas-to the modeling of such dynamic plasmas driven by nano-focused XFEL pulses in solid iron targets. In the case of the smallest focal spot investigated of just 100 nm in diameter, keV plasmas induce strong radial E-fields that accelerate keV ions radially as well as sheath fields that accelerate surface ions to hundreds of keV. The heated spot, which is initially larger than the laser spot due to the kinetic nature of the fast Auger electrons, expands as ion and electron waves propagate radially, leaving a low density region along the laser axis. This research was supported by the US DOE-OFES under Grant No. DE-SC0008827, the DOE-NNSA under Grant No. DE-NA0002075, and the JSPS KAKENHI under Grant No. JP15K21767.

Electrostatic Unfolding and Interactions of Albumin Driven by pH Changes: A Molecular Dynamics Study

PubMed Central

2015-01-01

A better understanding of protein aggregation is bound to translate into critical advances in several areas, including the treatment of misfolded protein disorders and the development of self-assembling biomaterials for novel commercial applications. Because of its ubiquity and clinical potential, albumin is one of the best-characterized models in protein aggregation research; but its properties in different conditions are not completely understood. Here, we carried out all-atom molecular dynamics simulations of albumin to understand how electrostatics can affect the conformation of a single albumin molecule just prior to self-assembly. We then analyzed the tertiary structure and solvent accessible surface area of albumin after electrostatically triggered partial denaturation. The data obtained from these single protein simulations allowed us to investigate the effect of electrostatic interactions between two proteins. The results of these simulations suggested that hydrophobic attractions and counterion binding may be strong enough to effectively overcome the electrostatic repulsions between the highly charged monomers. This work contributes to our general understanding of protein aggregation mechanisms, the importance of explicit consideration of free ions in protein solutions, provides critical new insights about the equilibrium conformation of albumin in its partially denatured state at low pH, and may spur significant progress in our efforts to develop biocompatible protein hydrogels driven by electrostatic partial denaturation. PMID:24393011

76 FR 72686 - 36(b)(1) Arms Sales Notification

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-25

... Electromagnetic Aircraft Launch System/Advanced Arresting Gear (EMALS/AAG). The EMALS long lead sub-assemblies... United Kingdom--Electromagnetic Aircraft Launch System Long Lead Sub- Assemblies The Government of the United Kingdom (UK) has requested the long lead sub-assemblies for the Electromagnetic Aircraft Launch...

Particle acceleration in solar active regions being in the state of self-organized criticality.

NASA Astrophysics Data System (ADS)

Vlahos, Loukas

We review the recent observational results on flare initiation and particle acceleration in solar active regions. Elaborating a statistical approach to describe the spatiotemporally intermittent electric field structures formed inside a flaring solar active region, we investigate the efficiency of such structures in accelerating charged particles (electrons and protons). The large-scale magnetic configuration in the solar atmosphere responds to the strong turbulent flows that convey perturbations across the active region by initiating avalanche-type processes. The resulting unstable structures correspond to small-scale dissipation regions hosting strong electric fields. Previous research on particle acceleration in strongly turbulent plasmas provides a general framework for addressing such a problem. This framework combines various electromagnetic field configurations obtained by magnetohydrodynamical (MHD) or cellular automata (CA) simulations, or by employing a statistical description of the field’s strength and configuration with test particle simulations. We work on data-driven 3D magnetic field extrapolations, based on a self-organized criticality models (SOC). A relativistic test-particle simulation traces each particle’s guiding center within these configurations. Using the simulated particle-energy distributions we test our results against observations, in the framework of the collisional thick target model (CTTM) of solar hard X-ray (HXR) emission and compare our results with the current observations.

Study on transient beam loading compensation for China ADS proton linac injector II

NASA Astrophysics Data System (ADS)

Gao, Zheng; He, Yuan; Wang, Xian-Wu; Chang, Wei; Zhang, Rui-Feng; Zhu, Zheng-Long; Zhang, Sheng-Hu; Chen, Qi; Powers, Tom

2016-05-01

Significant transient beam loading effects were observed during beam commissioning tests of prototype II of the injector for the accelerator driven sub-critical (ADS) system, which took place at the Institute of Modern Physics, Chinese Academy of Sciences, between October and December 2014. During these tests experiments were performed with continuous wave (CW) operation of the cavities with pulsed beam current, and the system was configured to make use of a prototype digital low level radio frequency (LLRF) controller. The system was originally operated in pulsed mode with a simple proportional plus integral and deviation (PID) feedback control algorithm, which was not able to maintain the desired gradient regulation during pulsed 10 mA beam operations. A unique simple transient beam loading compensation method which made use of a combination of proportional and integral (PI) feedback and feedforward control algorithm was implemented in order to significantly reduce the beam induced transient effect in the cavity gradients. The superconducting cavity field variation was reduced to less than 1.7% after turning on this control algorithm. The design and experimental results of this system are presented in this paper. Supported by National Natural Science Foundation of China (91426303, 11525523)

Microbial community assembly patterns under incipient conditions in a basaltic soil system

NASA Astrophysics Data System (ADS)

Sengupta, A.; Stegen, J.; Alves Meira Neto, A.; Wang, Y.; Chorover, J.; Troch, P. A. A.; Maier, R. M.

2017-12-01

In sub-surface environments, the biotic components are critically linked to the abiotic processes. However, there is limited understanding of community establishment, functional associations, and community assembly processes of such microbes in sub-surface environments. This study presents the first analysis of microbial signatures in an incipient terrestrial basalt soil system conducted under controlled conditions. A sub-meter scale sampling of a soil mesocosm revealed the contrasting distribution patterns of simple soil parameters such as bulk density and electrical conductivity. Phylogenetic analysis of 16S rRNA gene indicated the presence of a total 40 bacterial and archaeal phyla, with high relative abundance of Actinobacteria on the surface and highest abundance of Proteobacteria throughout the system. Community diversity patterns were inferred to be dependent on depth profile and average water content in the system. Predicted functional gene analysis suggested mixotrophy lifestyles with both autotrophic and heterotrophic metabolisms, likelihood of a unique salt tolerant methanogenic pathway with links to novel Euryarchea, signatures of an incomplete nitrogen cycle, and predicted enzymes of extracellular iron (II) to iron (III) conversion followed by intracellular uptake, transport and regulation. Null modeling revealed microbial community assembly was predominantly governed by variable selection, but the influence of the variable selection did not show systematic spatial structure. The presence of significant heterogeneity in predicted functions and ecologically deterministic shifts in community composition in a homogeneous incipient basalt highlights the complexity exhibited by microorganisms even in the simplest of environmental systems. This presents an opportunity to further develop our understanding of how microbial communities establish, evolve, impact, and respond in sub-surface environments.

Cumulative neutrino background from quasar-driven outflows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Xiawei; Loeb, Abraham, E-mail: xiawei.wang@cfa.harvard.edu, E-mail: aloeb@cfa.harvard.edu

2016-12-01

Quasar-driven outflows naturally account for the missing component of the extragalactic γ-ray background through neutral pion production in interactions between protons accelerated by the forward outflow shock and interstellar protons. We study the simultaneous neutrino emission by the same protons. We adopt outflow parameters that best fit the extragalactic γ-ray background data and derive a cumulative neutrino background of ∼ 10{sup −7} GeV cm{sup −2} s{sup −1} sr{sup −1} at neutrino energies E {sub ν} ∼> 10 TeV, which naturally explains the most recent IceCube data without tuning any free parameters. The link between the γ-ray and neutrino emission frommore » quasar outflows can be used to constrain the high-energy physics of strong shocks at cosmological distances.« less

Improvement of the 2D/1D Method in MPACT Using the Sub-Plane Scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graham, Aaron M; Collins, Benjamin S; Downar, Thomas

Oak Ridge National Laboratory and the University of Michigan are jointly developing the MPACTcode to be the primary neutron transport code for the Virtual Environment for Reactor Applications (VERA). To solve the transport equation, MPACT uses the 2D/1D method, which decomposes the problem into a stack of 2D planes that are then coupled with a 1D axial calculation. MPACT uses the Method of Characteristics for the 2D transport calculations and P3 for the 1D axial calculations, then accelerates the solution using the 3D Coarse mesh Finite Dierence (CMFD) method. Increasing the number of 2D MOC planes will increase the accuracymore » of the alculation, but will increase the computational burden of the calculations and can cause slow convergence or instability. To prevent these problems while maintaining accuracy, the sub-plane scheme has been implemented in MPACT. This method sub-divides the MOC planes into sub-planes, refining the 1D P3 and 3D CMFD calculations without increasing the number of 2D MOC planes. To test the sub-plane scheme, three of the VERA Progression Problems were selected: Problem 3, a single assembly problem; Problem 4, a 3x3 assembly problem with control rods and pyrex burnable poisons; and Problem 5, a quarter core problem. These three problems demonstrated that the sub-plane scheme can accurately produce intra-plane axial flux profiles that preserve the accuracy of the fine mesh solution. The eigenvalue dierences are negligibly small, and dierences in 3D power distributions are less than 0.1% for realistic axial meshes. Furthermore, the convergence behavior with the sub-plane scheme compares favorably with the conventional 2D/1D method, and the computational expense is decreased for all calculations due to the reduction in expensive MOC calculations.« less

Cyanobacteria in lakes on Yungui Plateau, China are assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use

PubMed Central

Liao, Jingqiu; Zhao, Lei; Cao, Xiaofeng; Sun, Jinhua; Gao, Zhe; Wang, Jie; Jiang, Dalin; Fan, Hao; Huang, Yi

2016-01-01

Plateau lakes are important ecosystems with diverse ecological functions. Cyanobacteria play a key role in plateau lakes as primary producers. However, they are threatening when dense blooms occur. Identifying cyanobacteiral biogeography and the mechanism of assembly processes shaping the distribution of cyanobacteria in plateau lakes is critical for understanding cyanobacterial ecology and applying it to lake management. In the present study, the biogeographic pattern and importance of neutral and niche processes in assembly of cyanobacteria in 21 lakes on Yungui Plateau, China were examined. Results showed that cyanobacteria exhibit unique biogeographic pattern, and most of them have a narrow habitat preference in plateau lakes. They were assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use, which explained 62.4% of the biological variation. Neutral processes were not at play. Water physicochemical property (key variables - dissolved oxygen, salinity, trophic status and pH) was the most dominant driver shaping its unique biogeographic pattern. Watershed land-use especially urban land, water body and agricultural land also exhibited a strong impact on cyanobacterial distribution, followed by lake morphology. As most of the cyanobacteiral genus detected in these plateau lakes were potential toxin-producers, this study indicated that in order to protect waters from toxic-bloom in the future, reducing nutrient loading and land-use practices are two practical approaches in plateau lake management. PMID:27819304

Cyanobacteria in lakes on Yungui Plateau, China are assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use

NASA Astrophysics Data System (ADS)

Liao, Jingqiu; Zhao, Lei; Cao, Xiaofeng; Sun, Jinhua; Gao, Zhe; Wang, Jie; Jiang, Dalin; Fan, Hao; Huang, Yi

2016-11-01

Plateau lakes are important ecosystems with diverse ecological functions. Cyanobacteria play a key role in plateau lakes as primary producers. However, they are threatening when dense blooms occur. Identifying cyanobacteiral biogeography and the mechanism of assembly processes shaping the distribution of cyanobacteria in plateau lakes is critical for understanding cyanobacterial ecology and applying it to lake management. In the present study, the biogeographic pattern and importance of neutral and niche processes in assembly of cyanobacteria in 21 lakes on Yungui Plateau, China were examined. Results showed that cyanobacteria exhibit unique biogeographic pattern, and most of them have a narrow habitat preference in plateau lakes. They were assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use, which explained 62.4% of the biological variation. Neutral processes were not at play. Water physicochemical property (key variables - dissolved oxygen, salinity, trophic status and pH) was the most dominant driver shaping its unique biogeographic pattern. Watershed land-use especially urban land, water body and agricultural land also exhibited a strong impact on cyanobacterial distribution, followed by lake morphology. As most of the cyanobacteiral genus detected in these plateau lakes were potential toxin-producers, this study indicated that in order to protect waters from toxic-bloom in the future, reducing nutrient loading and land-use practices are two practical approaches in plateau lake management.

Cyanobacteria in lakes on Yungui Plateau, China are assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use.

PubMed

Liao, Jingqiu; Zhao, Lei; Cao, Xiaofeng; Sun, Jinhua; Gao, Zhe; Wang, Jie; Jiang, Dalin; Fan, Hao; Huang, Yi

2016-11-07

Plateau lakes are important ecosystems with diverse ecological functions. Cyanobacteria play a key role in plateau lakes as primary producers. However, they are threatening when dense blooms occur. Identifying cyanobacteiral biogeography and the mechanism of assembly processes shaping the distribution of cyanobacteria in plateau lakes is critical for understanding cyanobacterial ecology and applying it to lake management. In the present study, the biogeographic pattern and importance of neutral and niche processes in assembly of cyanobacteria in 21 lakes on Yungui Plateau, China were examined. Results showed that cyanobacteria exhibit unique biogeographic pattern, and most of them have a narrow habitat preference in plateau lakes. They were assembled via niche processes driven by water physicochemical property, lake morphology and watershed land-use, which explained 62.4% of the biological variation. Neutral processes were not at play. Water physicochemical property (key variables - dissolved oxygen, salinity, trophic status and pH) was the most dominant driver shaping its unique biogeographic pattern. Watershed land-use especially urban land, water body and agricultural land also exhibited a strong impact on cyanobacterial distribution, followed by lake morphology. As most of the cyanobacteiral genus detected in these plateau lakes were potential toxin-producers, this study indicated that in order to protect waters from toxic-bloom in the future, reducing nutrient loading and land-use practices are two practical approaches in plateau lake management.

The role of accelerators in the nuclear fuel cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takahashi, Hiroshi.

1990-01-01

The use of neutrons produced by the medium energy proton accelerator (1 GeV--3 GeV) has considerable potential in reconstructing the nuclear fuel cycle. About 1.5 {approximately} 2.5 ton of fissile material can be produced annually by injecting a 450 MW proton beam directly into fertile materials. A source of neutrons, produced by a proton beam, to supply subcritical reactors could alleviate many of the safety problems associated with critical assemblies, such as positive reactivity coefficients due to coolant voiding. The transient power of the target can be swiftly controlled by controlling the power of the proton beam. Also, the usemore » of a proton beam would allow more flexibility in the choice of fuel and structural materials which otherwise might reduce the reactivity of reactors. This paper discusses the rate of accelerators in the transmutation of radioactive wastes of the nuclear fuel cycles. 34 refs., 17 figs., 9 tabs.« less

On the shedding of impaled droplets: The role of transient intervening layers

NASA Astrophysics Data System (ADS)

Stamatopoulos, Christos; Schutzius, Thomas M.; Köppl, Christian J.; Hayek, Nicolas El; Maitra, Tanmoy; Hemrle, Jaroslav; Poulikakos, Dimos

2016-01-01

Maintaining the non-wetting property of textured hydrophobic surfaces is directly related to the preservation of an intervening fluid layer (gaseous or immiscible liquid) between the droplet and substrate; once displaced, it cannot be recovered spontaneously as the fully penetrated Wenzel wetting state is energetically favorable. Here, we identify pathways for the “lifting” of droplets from the surface texture, enabling a complete Wenzel-to-Cassie-Baxter wetting state transition. This is accomplished by the hemiwicking of a transient (limited lifetime due to evaporation) low surface tension (LST) liquid, which is capable of self-assembling as an intervening underlayer, lifting the droplet from its impaled state and facilitating a skating-like behavior. In the skating phase, a critical substrate tilting angle is identified, up to which underlayer and droplet remain coupled exhibiting a pseudo-Cassie-Baxter state. For greater titling angles, the droplet, driven by inertia, detaches itself from the liquid intervening layer and transitions to a traditional Cassie-Baxter wetting state, thereby accelerating and leaving the underlayer behind. A model is also presented that elucidates the mechanism of mobility recovery. Ultimately, this work provides a better understanding of multiphase mass transfer of immiscible LST liquid-water mixtures with respect to establishing facile methods towards retaining intervening layers.

On the shedding of impaled droplets: The role of transient intervening layers

PubMed Central

Stamatopoulos, Christos; Schutzius, Thomas M.; Köppl, Christian J.; Hayek, Nicolas El; Maitra, Tanmoy; Hemrle, Jaroslav; Poulikakos, Dimos

2016-01-01

Maintaining the non-wetting property of textured hydrophobic surfaces is directly related to the preservation of an intervening fluid layer (gaseous or immiscible liquid) between the droplet and substrate; once displaced, it cannot be recovered spontaneously as the fully penetrated Wenzel wetting state is energetically favorable. Here, we identify pathways for the “lifting” of droplets from the surface texture, enabling a complete Wenzel-to-Cassie-Baxter wetting state transition. This is accomplished by the hemiwicking of a transient (limited lifetime due to evaporation) low surface tension (LST) liquid, which is capable of self-assembling as an intervening underlayer, lifting the droplet from its impaled state and facilitating a skating-like behavior. In the skating phase, a critical substrate tilting angle is identified, up to which underlayer and droplet remain coupled exhibiting a pseudo-Cassie-Baxter state. For greater titling angles, the droplet, driven by inertia, detaches itself from the liquid intervening layer and transitions to a traditional Cassie-Baxter wetting state, thereby accelerating and leaving the underlayer behind. A model is also presented that elucidates the mechanism of mobility recovery. Ultimately, this work provides a better understanding of multiphase mass transfer of immiscible LST liquid-water mixtures with respect to establishing facile methods towards retaining intervening layers. PMID:26743806

Sensitivity of Nb$$_3$$Sn Rutherford-Type Cables to Transverse Pressure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barzi, E.; Wokas, T.; Zlobin, A. V.

Fermilab is developing high field superconducting magnets for future accelerators based on Nb/sub 3/Sn strands. Testing the critical current of superconducting cables under compression is a means to appraise the performance of the produced magnet. However, these cable tests are expensive and labor-intensive. A fixture to assess the superconducting performance of a Nb/sub 3/Sn strand within a reacted and impregnated cable under pressure was designed and built at Fermilab. Several Rutherford-type cables were fabricated at Fermilab and at LBNL using multifilamentary Nb/sub 3/Sn strands. The sensitivity of Nb/sub 3/Sn to transverse pressure was measured for a number of Nb/sub 3/Snmore » technologies (Modified Jelly Roll, Powder-in-Tube, Internal Tin, and Restack Rod Process). Results on the effect of a stainless steel core in the cable are also shown.« less

Laminated magnet field coil sheath

DOEpatents

Skaritka, John R.

1987-12-01

a method for manufacturing a magnet cable trim coil in a sheath assembly for use in a cryogenic particle accelerator. A precisely positioned pattern of trim coil turns is bonded to a flexible substrate sheath that is capable of withstanding cryogenic operating conditions. In the method of the invention the flexible sheath, with the trim coil pattern precisely positioned thereon, is accurately positioned at a precise location relative to a bore tube assembly of an accelerator and is then bonded to the bore tube with a tape suitable for cryogenic application. The resultant assembly can be readily handled and installed within an iron magnet yoke assembly of a suitable cryogenic particle accelerator.

Laminated magnet field coil sheath

DOEpatents

Skaritka, J.R.

1987-05-15

A method for manufacturing a magnetic cable trim coil in a sheath assembly for use in a cryogenic particle accelerator. A precisely positioned pattern of trim coil turns is bonded to a flexible substrate sheath that is capable of withstanding cryogenic operating conditions. In the method of the invention the flexible substrate sheath, with the trim coil pattern precisely location relative to a bore tube assembly of an accelerator and is then bonded to the bore tube with a tape suitable for cryogenic application. The resultant assembly can be readily handled and installed within an iron magnet yoke assembly of a suitable cryogenic particle accelerator. 1 fig.

Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges

PubMed Central

Fujiwara, Ikuko; Remmert, Kirsten; Piszczek, Grzegorz; Hammer, John A.

2014-01-01

Although capping protein (CP) terminates actin filament elongation, it promotes Arp2/3-dependent actin network assembly and accelerates actin-based motility both in vitro and in vivo. In vitro, capping protein Arp2/3 myosin I linker (CARMIL) antagonizes CP by reducing its affinity for the barbed end and by uncapping CP-capped filaments, whereas the protein V-1/myotrophin sequesters CP in an inactive complex. Previous work showed that CARMIL can readily retrieve CP from the CP:V-1 complex, thereby converting inactive CP into a version with moderate affinity for the barbed end. Here we further clarify the mechanism of this exchange reaction, and we demonstrate that the CP:CARMIL complex created by complex exchange slows the rate of barbed-end elongation by rapidly associating with, and dissociating from, the barbed end. Importantly, the cellular concentrations of V-1 and CP determined here argue that most CP is sequestered by V-1 at steady state in vivo. Finally, we show that CARMIL is recruited to the plasma membrane and only at cell edges undergoing active protrusion. Assuming that CARMIL is active only at this location, our data argue that a large pool of freely diffusing, inactive CP (CP:V-1) feeds, via CARMIL-driven complex exchange, the formation of weak-capping complexes (CP:CARMIL) at the plasma membrane of protruding edges. In vivo, therefore, CARMIL should promote Arp2/3-dependent actin network assembly at the leading edge by promoting barbed-end capping there. PMID:24778263

DOE Office of Scientific and Technical Information (OSTI.GOV)

McAdams, Brian J.; Pearson, Raymond A.

With the continuing trend of decreasing feature sizes in flip-chip assemblies, the reliability tolerance to interfacial flaws is also decreasing. Small-scale disbonds will become more of a concern, pointing to the need for a better understanding of the initiation stage of interfacial delamination. With most accepted adhesion metric methodologies tailored to predict failure under the prior existence of a disbond, the study of the initiation phenomenon is open to development and standardization of new testing procedures. Traditional fracture mechanics approaches are not suitable, as the mathematics assume failure to originate at a disbond or crack tip. Disbond initiation is believedmore » to first occur at free edges and corners, which act as high stress concentration sites and exhibit singular stresses similar to a crack tip, though less severe in intensity. As such, a 'fracture mechanics-like' approach may be employed which defines a material parameter--a critical stress intensity factor (K{sub c})--that can be used to predict when initiation of a disbond at an interface will occur. The factors affecting the adhesion of underfill/polyimide interfaces relevant to flip-chip assemblies were investigated in this study. The study consisted of two distinct parts: a comparison of the initiation and propagation phenomena and a comparison of the relationship between sub-critical and critical initiation of interfacial failure. The initiation of underfill interfacial failure was studied by characterizing failure at a free-edge with a critical stress intensity factor. In comparison with the interfacial fracture toughness testing, it was shown that a good correlation exists between the initiation and propagation of interfacial failures. Such a correlation justifies the continuing use of fracture mechanics to predict the reliability of flip-chip packages. The second aspect of the research involved fatigue testing of tensile butt joint specimens to determine lifetimes at sub-critical load levels. The results display an interfacial strength ranking similar to that observed during monotonic testing. The fatigue results indicate that monotonic fracture mechanics testing may be an adequate screening tool to help predict cyclic underfill failure; however lifetime data is required to predict reliability.« less

RF structure design of the China Material Irradiation Facility RFQ

NASA Astrophysics Data System (ADS)

Li, Chenxing; He, Yuan; Xu, Xianbo; Zhang, Zhouli; Wang, Fengfeng; Dou, Weiping; Wang, Zhijun; Wang, Tieshan

2017-10-01

The radio frequency structure design of the radio frequency quadrupole (RFQ) for the front end of China Material Irradiation Facility (CMIF), which is an accelerator based neutron irradiation facility for fusion reactor material qualification, has been completed. The RFQ is specified to accelerate 10 mA continuous deuteron beams from the energies of 20 keV/u to 1.5 MeV/u within the vane length of 5250 mm. The working frequency of the RFQ is selected to 162.5 MHz and the inter-vane voltage is set to 65 kV. Four-vane cavity type is selected and the cavity structure is designed drawing on the experience of China Initiative Accelerator Driven System (CIADS) Injector II RFQ. In order to reduce the azimuthal asymmetry of the field caused from errors in fabrication and assembly, a frequency separation between the working mode and its nearest dipole mode is reached to 17.66 MHz by utilizing 20 pairs of π-mode stabilizing loops (PISLs) distributed along the longitudinal direction with equal intervals. For the purpose of tuning, 100 slug tuners were introduced to compensate the errors caused by machining and assembly. In order to obtain a homogeneous electrical field distribution along cavity, vane cutbacks are introduced and output endplate is modified. Multi-physics study of the cavity with radio frequency power and water cooling is performed to obtain the water temperature tuning coefficients. Through comparing to the worldwide CW RFQs, it is indicated that the power density of the designed structure is moderate for operation under continuous wave (CW) mode.

A mechanically driven form of Kirigami as a route to 3D mesostructures in micro/nanomembranes

DOE PAGES

Zhang, Yihui; Yan, Zheng; Nan, Kewang; ...

2015-09-08

Assembly of 3D micro/nanostructures in advanced functional materials has important implications across broad areas of technology. Existing approaches are compatible, however, only with narrow classes of materials and/or 3D geometries. This article introduces ideas for a form of Kirigami that allows precise, mechanically driven assembly of 3D mesostructures of diverse materials from 2D micro/nanomembranes with strategically designed geometries and patterns of cuts. Theoretical and experimental studies demonstrate applicability of the methods across length scales from macro to nano, in materials ranging from monocrystalline silicon to plastic, with levels of topographical complexity that significantly exceed those that can be achieved usingmore » other approaches. A broad set of examples includes 3D silicon mesostructures and hybrid nanomembrane-nanoribbon systems, including heterogeneous combinations with polymers and metals, with critical dimensions that range from 100 nm to 30 mm. Lastly, a 3D mechanically tunable optical transmission window provides an application example of this Kirigami process, enabled by theoretically guided design.« less

Cardiopulmonary Responses to Supine Cycling during Short-Arm Centrifugation

NASA Technical Reports Server (NTRS)

Vener, J. M.; Simonson, S. R.; Stocks, J.; Evettes, S.; Bailey, K.; Biagini, H.; Jackson, C. G. R.; Greenleaf, J. E.; Dalton, Bonnie P. (Technical Monitor)

2001-01-01

The purpose of this study was to investigate cardiopulmonary responses to supine cycling with concomitant +G(sub z) acceleration using the NASA/Ames Human Powered Short-Arm Centrifuge (HPC). Subjects were eight consenting males (32+/-5 yrs, 178+/-5 cm, 86.1+/- 6.2 kg). All subjects completed two maximal exercise tests on the HPC (with and without acceleration) within a three-day period. A two tailed t-test with statistical significance set at p less than or equal to 0.05 was used to compare treatments. Peak acceleration was 3.4+/-0.1 G(sub z), (head to foot acceleration). Peak oxygen uptake (VO2(sub peak) was not different between treatment groups (3.1+/-0.1 Lmin(exp -1) vs. 3.2+/-0.1 Lmin(exp -1) for stationary and acceleration trials, respectively). Peak HR and pulmonary minute ventilation (V(sub E(sub BTPS))) were significantly elevated (p less than or equal to 0.05) for the acceleration trial (182+/-3 BPM (Beats per Minute); 132.0+/-9.0 Lmin(exp -1)) when compared to the stationary trial (175+/-3 BPM; 115.5+/-8.5 Lmin(exp -1)). Ventilatory threshold expressed as a percent of VO2(sub peak) was not different for acceleration and stationary trials (72+/-2% vs. 68+/-2% respectively). Results suggest that 3.4 G(sub z) acceleration does not alter VO2(sub peak) response to supine cycling. However, peak HR and V(sub E(sub BTPS)) response may be increased while ventilatory threshold response expressed as a function of percent VO2(sub peak) is relatively unaffected. Thus, traditional exercise prescription based on VO2 response would be appropriate for this mode of exercise. Prescriptions based on HR response may require modification.

Dynamics of the driven Goodwin business cycle equation

NASA Astrophysics Data System (ADS)

Antonova, A. O.; Reznik, S. N.; Todorov, M. D.

2015-10-01

We study dynamics of the Goodwin nonlinear accelerator business cycle model with periodic forced autonomous investment Ia(t) = a(1 - cos ωt), where a and ω are the amplitude and the frequency of investment. We give examples of the parameters a and ω when the chaotic oscillations of income are possible. We find the critical values of amplitude acr (ω): if a > acr (ω) the period of the income equals to the driving period T=2π/ω.

Compressive power spectrum sensing for vibration-based output-only system identification of structural systems in the presence of noise

NASA Astrophysics Data System (ADS)

Tau Siesakul, Bamrung; Gkoktsi, Kyriaki; Giaralis, Agathoklis

2015-05-01

Motivated by the need to reduce monetary and energy consumption costs of wireless sensor networks in undertaking output-only/operational modal analysis of engineering structures, this paper considers a multi-coset analog-toinformation converter for structural system identification from acceleration response signals of white noise excited linear damped structures sampled at sub-Nyquist rates. The underlying natural frequencies, peak gains in the frequency domain, and critical damping ratios of the vibrating structures are estimated directly from the sub-Nyquist measurements and, therefore, the computationally demanding signal reconstruction step is by-passed. This is accomplished by first employing a power spectrum blind sampling (PSBS) technique for multi-band wide sense stationary stochastic processes in conjunction with deterministic non-uniform multi-coset sampling patterns derived from solving a weighted least square optimization problem. Next, modal properties are derived by the standard frequency domain peak picking algorithm. Special attention is focused on assessing the potential of the adopted PSBS technique, which poses no sparsity requirements to the sensed signals, to derive accurate estimates of modal structural system properties from noisy sub- Nyquist measurements. To this aim, sub-Nyquist sampled acceleration response signals corrupted by various levels of additive white noise pertaining to a benchmark space truss structure with closely spaced natural frequencies are obtained within an efficient Monte Carlo simulation-based framework. Accurate estimates of natural frequencies and reasonable estimates of local peak spectral ordinates and critical damping ratios are derived from measurements sampled at about 70% below the Nyquist rate and for SNR as low as 0db demonstrating that the adopted approach enjoys noise immunity.

Superconductive radiofrequency window assembly

DOEpatents

Phillips, Harry Lawrence; Elliott, Thomas S.

1998-01-01

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly (20) has a superconducting metal-ceramic design. The srf window assembly (20) comprises a superconducting frame (30), a ceramic plate (40) having a superconducting metallized area, and a superconducting eyelet (50) for sealing plate (40) into frame (30). The plate (40) is brazed to eyelet (50) which is then electron beam welded to frame (30). A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator.

Superconductive radiofrequency window assembly

DOEpatents

Phillips, H.L.; Elliott, T.S.

1998-05-19

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The SRF window assembly has a superconducting metal-ceramic design. The SRF window assembly comprises a superconducting frame, a ceramic plate having a superconducting metallized area, and a superconducting eyelet for sealing plate into frame. The plate is brazed to eyelet which is then electron beam welded to frame. A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the SRF window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator. 11 figs.

Superconducting radiofrequency window assembly

DOEpatents

Phillips, Harry L.; Elliott, Thomas S.

1997-01-01

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly (20) has a superconducting metal-ceramic design. The srf window assembly (20) comprises a superconducting frame (30), a ceramic plate (40) having a superconducting metallized area, and a superconducting eyelet (50) for sealing plate (40) into frame (30). The plate (40) is brazed to eyelet (50) which is then electron beam welded to frame (30). A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator.

Superconducting radiofrequency window assembly

DOEpatents

Phillips, H.L.; Elliott, T.S.

1997-03-11

The present invention is a superconducting radiofrequency window assembly for use in an electron beam accelerator. The srf window assembly has a superconducting metal-ceramic design. The srf window assembly comprises a superconducting frame, a ceramic plate having a superconducting metallized area, and a superconducting eyelet for sealing plate into frame. The plate is brazed to eyelet which is then electron beam welded to frame. A method for providing a ceramic object mounted in a metal member to withstand cryogenic temperatures is also provided. The method involves a new metallization process for coating a selected area of a ceramic object with a thin film of a superconducting material. Finally, a method for assembling an electron beam accelerator cavity utilizing the srf window assembly is provided. The procedure is carried out within an ultra clean room to minimize exposure to particulates which adversely affect the performance of the cavity within the electron beam accelerator. 11 figs.

Independent Orbiter Assessment (IOA): Analysis of the displays and controls subsystem

NASA Technical Reports Server (NTRS)

Trahan, W. H.; Prust, E. E.

1987-01-01

The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality, and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. This report documents the independent analysis results corresponding to the Orbiter Displays and Controls (D and C) subsystem hardware. The function of the D and C hardware is to provide the crew with the monitor, command, and control capabilities required for management of all normal and contingency mission and flight operations. The D and C hardware for which failure modes analysis was performed consists of the following: Acceleration Indicator (G-METER); Head Up Display (HUD); Display Driver Unit (DDU); Alpha/Mach Indicator (AMI); Horizontal Situation Indicator (HSI); Attitude Director Indicator (ADI); Propellant Quantity Indicator (PQI); Surface Position Indicator (SPI); Altitude/Vertical Velocity Indicator (AVVI); Caution and Warning Assembly (CWA); Annunciator Control Assembly (ACA); Event Timer (ET); Mission Timer (MT); Interior Lighting; and Exterior Lighting. Each hardware item was evaluated and analyzed for possible failure modes and effects. Criticality was assigned based upon the severity of the effect for each failure mode.

The IPHI Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferdinand, Robin; Beauvais, Pierre-Yves

High Power Proton Accelerators (HPPAs) are studied for several projects based on high-flux neutron sources driven by proton or deuteron beams. Since the front end is considered as the most critical part of such accelerators, the two French national research agencies CEA and CNRS decided to collaborate in 1997 to study and build a High-Intensity Proton Injector (IPHI). The main objective of this project is to master the complex technologies used and the concepts of manufacturing and controlling the HPPAs. Recently, a collaboration agreement was signed with CERN and led to some evolutions in the design and in the schedule.more » The IPHI design current was maintained at 100 mA in Continuous Wave mode. This choice should allow to produce a high reliability beam at reduced intensity (typically 30 mA) tending to fulfill the Accelerator Driven System requirements. The output energy of the Radio Frequency Quadrupole (RFQ), was reduced from 5 to 3 MeV, allowing then the adjunction and the test, in pulsed operation of a chopper line developed by CERN for the Superconducting Proton Linac (SPL). In a final step, the IPHI RFQ and the chopper line should become parts of the SPL injector. In this paper, the IPHI project and the recent evolutions are reported together with the construction and operation schedule.« less

Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications.

PubMed

Zhu, Guizhi; Hu, Rong; Zhao, Zilong; Chen, Zhuo; Zhang, Xiaobing; Tan, Weihong

2013-11-06

DNA nanotechnology has been extensively explored to assemble various functional nanostructures for versatile applications. Mediated by Watson-Crick base-pairing, these DNA nanostructures have been conventionally assembled through hybridization of many short DNA building blocks. Here we report the noncanonical self-assembly of multifunctional DNA nanostructures, termed as nanoflowers (NFs), and the versatile biomedical applications. These NFs were assembled from long DNA building blocks generated via rolling circle replication (RCR) of a designer template. NF assembly was driven by liquid crystallization and dense packaging of building blocks, without relying on Watson-Crick base-pairing between DNA strands, thereby avoiding the otherwise conventional complicated DNA sequence design. NF sizes were readily tunable in a wide range, by simply adjusting such parameters as assembly time and template sequences. NFs were exceptionally resistant to nuclease degradation, denaturation, or dissociation at extremely low concentration, presumably resulting from the dense DNA packaging in NFs. The exceptional biostability is critical for biomedical applications. By rational design, NFs can be readily incorporated with myriad functional moieties. All these properties make NFs promising for versatile applications. As a proof-of-principle demonstration, in this study, NFs were integrated with aptamers, bioimaging agents, and drug loading sites, and the resultant multifunctional NFs were demonstrated for selective cancer cell recognition, bioimaging, and targeted anticancer drug delivery.

Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications

PubMed Central

Zhu, Guizhi; Hu, Rong; Zhao, Zilong; Chen, Zhuo; Zhang, Xiaobing; Tan, Weihong

2013-01-01

DNA nanotechnology has been extensively explored to assemble various functional nanostructures for versatile applications. Mediated by Watson-Crick base-pairing, these DNA nanostructures have been conventionally assembled through hybridization of many short DNA building blocks. Here we report the noncanonical self-assembly of multifunctional DNA nanostructures, termed as nanoflowers (NFs), and the versatile biomedical applications. These NFs were assembled from long DNA building blocks generated via Rolling Circle Replication (RCR) of a designer template. NF assembly was driven by liquid crystallization and dense packaging of building blocks, without relying on Watson-Crick base-pairing between DNA strands, thereby avoiding the otherwise conventional complicated DNA sequence design. NF sizes were readily tunable in a wide range, by simply adjusting such parameters as assembly time and template sequences. NFs were exceptionally resistant to nuclease degradation, denaturation, or dissociation at extremely low concentration, presumably resulting from the dense DNA packaging in NFs. The exceptional biostability is critical for biomedical applications. By rational design, NFs can be readily incorporated with myriad functional moieties. All these properties make NFs promising for versatile applications. As a proof-of-principle demonstration, in this study, NFs were integrated with aptamers, bioimaging agents, and drug loading sites, and the resultant multifunctional NFs were demonstrated for selective cancer cell recognition, bioimaging, and targeted anticancer drug delivery. PMID:24164620

On the maximum energy achievable in the first order Fermi acceleration at shocks

NASA Astrophysics Data System (ADS)

Grozny, I.; Diamond, P.; Malkov, M.

2002-11-01

Astrophysical shocks are considered as the sites of cosmic ray (CR) production. The primary mechanism is the diffusive shock (Fermi) acceleration which operates via multiple shock recrossing by a particle. Its efficiency, the rate of energy gain, and the maximum energy are thus determined by the transport mechanisms (confinement to the shock) of these particles in a turbulent shock environment. The turbulence is believed to be generated by accelerated particles themselves. Moreover, in the most interesting case of efficient acceleration the entire MHD shock structure is dominated by their pressure. This makes this problem one of the challenging strongly nonlinear problems of astrophysics. We suggest a physical model that describes particle acceleration, shock structure and the CR driven turbulence on an equal footing. The key new element in this scheme is nonlinear cascading of the MHD turbulence on self-excited (via modulational and Drury instability) sound-like perturbations which gives rise to a significant enrichment of the long wave part of the MHD spectrum. This is critical for the calculation of the maximum energy.

Self-assembly of Carbon Vacancies in Sub-stoichiometric ZrC1−x

PubMed Central

Zhang, Yanhui; Liu, Bin; Wang, Jingyang

2015-01-01

Sub-stoichiometric interstitial compounds, including binary transition metal carbides (MC1−x), maintain structural stability even if they accommodate abundant anion vacancies. This unique character endows them with variable-composition, diverse-configuration and controllable-performance through composition and structure design. Herein, the evolution of carbon vacancy (VC) configuration in sub-stoichiometric ZrC1−x is investigated by combining the cluster expansion method and first-principles calculations. We report the interesting self-assembly of VCs and the fingerprint VC configuration (VC triplet constructed by 3rd nearest neighboring vacancies) in all the low energy structures of ZrC1−x. When VC concentration is higher than the critical value of 0.5 (x > 0.5), the 2nd nearest neighboring VC configurations with strongly repulsive interaction inevitably appear, and meanwhile, the system energy (or formation enthalpy) of ZrC1−x increases sharply which suggests the material may lose phase stability. The present results clarify why ZrC1−x bears a huge amount of VCs, tends towards VC ordering, and retains stability up to a stoichiometry of x = 0.5. PMID:26667083

The NOvA Technical Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ayres, D.S.; Drake, G.R.; Goodman, M.C.

Technical Design Report (TDR) describes the preliminary design of the NOvA accelerator upgrades, NOvA detectors, detector halls and detector sites. Compared to the March 2006 and November 2006 NOvA Conceptual Design Reports (CDR), critical value engineering studies have been completed and the alternatives still active in the CDR have been narrowed to achieve a preliminary technical design ready for a Critical Decision 2 review. Many aspects of NOvA described this TDR are complete to a level far beyond a preliminary design. In particular, the access road to the NOvA Far Detector site in Minnesota has an advanced technical design atmore » a level appropriate for a Critical Decision 3a review. Several components of the accelerator upgrade and new neutrino detectors also have advanced technical designs appropriate for a Critical Decision 3a review. Chapter 1 is an Executive Summary with a short description of the NOvA project. Chapter 2 describes how the Fermilab NuMI beam will provide a narrow band beam of neutrinos for NOvA. Chapter 3 gives an updated overview of the scientific basis for the NOvA experiment, focusing on the primary goal to extend the search for {nu}{sub {mu}} {yields} {nu}{sub e} oscillations and measure the sin{sup 2}(2{theta}{sub 13}) parameter. This parameter has not been measured in any previous experiment and NOvA would extend the search by about an order of magnitude beyond the current limit. A secondary goal is to measure the dominant mode oscillation parameters, sin{sup 2}(2{theta}{sub 23}) and {Delta}m{sub 32}{sup 2} to a more precise level than previous experiments. Additional physics goals for NOvA are also discussed. Chapter 4 describes the Scientific Design Criteria which the Fermilab accelerator complex, NOvA detectors and NOvA detector sites must satisfy to meet the physics goals discussed in Chapter 3. Chapter 5 is an overview of the NOvA project. The changes in the design relative to the NOvA CDR are discussed. Chapter 6 summarizes the NOvA design performance relative to the Design Criteria set out in Chapter 4. Chapter 7 presents the Work Breakdown Structure dictionary at Level 3 and the Milestone dictionary. Chapters 8 through 17 then take each Level 2 WBS element of the NOvA project and present each part of the design in more detail than the overview given in Chapter 5. Specific technical design criteria are delineated for each part of the project in addition to the scientific design criteria outlined in Chapter 4. Changes in the design since the NOvA CDR are discussed in detail. The work remaining to bring each part of this preliminary design to a final design is outlined. Appendix A is a guide to other NOvA Project documentation with links to those documents.« less

Radiobiological study by using laser-driven proton beams

NASA Astrophysics Data System (ADS)

Yogo, A.; Sato, K.; Nishikino, M.; Mori, M.; Teshima, T.; Numasaki, H.; Murakami, M.; Demizu, Y.; Akagi, S.; Nagayama, S.; Ogura, K.; Sagisaka, A.; Orimo, S.; Nishiuchi, M.; Pirozhkov, A. S.; Ikegami, M.; Tampo, M.; Sakaki, H.; Suzuki, M.; Daito, I.; Oishi, Y.; Sugiyama, H.; Kiriyama, H.; Okada, H.; Kanazawa, S.; Kondo, S.; Shimomura, T.; Nakai, Y.; Tanoue, M.; Sugiyama, H.; Sasao, H.; Wakai, D.; Kawachi, T.; Nishimura, H.; Bolton, P. R.; Daido, H.

2009-07-01

Particle acceleration driven by high-intensity laser systems is widely attracting interest as a potential alternative to conventional ion acceleration, including ion accelerator applications to tumor therapy. Recent works have shown that a high intensity laser pulse can produce single proton bunches of a high current and a short pulse duration. This unique feature of laser-ion acceleration can lead to progress in the development of novel ion sources. However, there has been no experimental study of the biological effects of laser-driven ion beams. We describe in this report the first demonstrated irradiation effect of laser-accelerated protons on human lung cancer cells. In-vitro A549 cells are irradiated with a proton dose of 20 Gy, resulting in a distinct formation of γ-H2AX foci as an indicator of DNA double-strand breaks. This is a pioneering result that points to future investigations of the radiobiological effects of laser-driven ion beams. The laser-driven ion beam is apotential excitation source for time-resolved determination of hydroxyl (OH) radical yield, which will explore relationship between the fundamental chemical reactions of radiation effects and consequent biological processes.

Beam-driven acceleration in ultra-dense plasma media

DOE PAGES

Shin, Young-Min

2014-09-15

Accelerating parameters of beam-driven wakefield acceleration in an extremely dense plasma column has been analyzed with the dynamic framed particle-in-cell plasma simulator, and compared with analytic calculations. In the model, a witness beam undergoes a TeV/m scale alternating potential gradient excited by a micro-bunched drive beam in a 10 25 m -3 and 1.6 x 10 28 m -3 plasma column. The acceleration gradient, energy gain, and transformer ratio have been extensively studied in quasi-linear, linear-, and blowout-regimes. The simulation analysis indicated that in the beam-driven acceleration system a hollow plasma channel offers 20 % higher acceleration gradient by enlargingmore » the channel radius (r) from 0.2 Ap to 0.6 .Ap in a blowout regime. This paper suggests a feasibility of TeV/m scale acceleration with a hollow crystalline structure (e.g. nanotubes) of high electron plasma density.« less

Guided post-acceleration of laser-driven ions by a miniature modular structure

PubMed Central

Kar, Satyabrata; Ahmed, Hamad; Prasad, Rajendra; Cerchez, Mirela; Brauckmann, Stephanie; Aurand, Bastian; Cantono, Giada; Hadjisolomou, Prokopis; Lewis, Ciaran L. S.; Macchi, Andrea; Nersisyan, Gagik; Robinson, Alexander P. L.; Schroer, Anna M.; Swantusch, Marco; Zepf, Matt; Willi, Oswald; Borghesi, Marco

2016-01-01

All-optical approaches to particle acceleration are currently attracting a significant research effort internationally. Although characterized by exceptional transverse and longitudinal emittance, laser-driven ion beams currently have limitations in terms of peak ion energy, bandwidth of the energy spectrum and beam divergence. Here we introduce the concept of a versatile, miniature linear accelerating module, which, by employing laser-excited electromagnetic pulses directed along a helical path surrounding the laser-accelerated ion beams, addresses these shortcomings simultaneously. In a proof-of-principle experiment on a university-scale system, we demonstrate post-acceleration of laser-driven protons from a flat foil at a rate of 0.5 GeV m−1, already beyond what can be sustained by conventional accelerator technologies, with dynamic beam collimation and energy selection. These results open up new opportunities for the development of extremely compact and cost-effective ion accelerators for both established and innovative applications. PMID:27089200

Freshwater discharges drive high levels of methylmercury in Arctic marine biota.

PubMed

Schartup, Amina T; Balcom, Prentiss H; Soerensen, Anne L; Gosnell, Kathleen J; Calder, Ryan S D; Mason, Robert P; Sunderland, Elsie M

2015-09-22

Elevated levels of neurotoxic methylmercury in Arctic food-webs pose health risks for indigenous populations that consume large quantities of marine mammals and fish. Estuaries provide critical hunting and fishing territory for these populations, and, until recently, benthic sediment was thought to be the main methylmercury source for coastal fish. New hydroelectric developments are being proposed in many northern ecosystems, and the ecological impacts of this industry relative to accelerating climate changes are poorly characterized. Here we evaluate the competing impacts of climate-driven changes in northern ecosystems and reservoir flooding on methylmercury production and bioaccumulation through a case study of a stratified sub-Arctic estuarine fjord in Labrador, Canada. Methylmercury bioaccumulation in zooplankton is higher than in midlatitude ecosystems. Direct measurements and modeling show that currently the largest methylmercury source is production in oxic surface seawater. Water-column methylation is highest in stratified surface waters near the river mouth because of the stimulating effects of terrestrial organic matter on methylating microbes. We attribute enhanced biomagnification in plankton to a thin layer of marine snow widely observed in stratified systems that concentrates microbial methylation and multiple trophic levels of zooplankton in a vertically restricted zone. Large freshwater inputs and the extensive Arctic Ocean continental shelf mean these processes are likely widespread and will be enhanced by future increases in water-column stratification, exacerbating high biological methylmercury concentrations. Soil flooding experiments indicate that near-term changes expected from reservoir creation will increase methylmercury inputs to the estuary by 25-200%, overwhelming climate-driven changes over the next decade.

Transport synthetic acceleration for long-characteristics assembly-level transport problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zika, M.R.; Adams, M.L.

2000-02-01

The authors apply the transport synthetic acceleration (TSA) scheme to the long-characteristics spatial discretization for the two-dimensional assembly-level transport problem. This synthetic method employs a simplified transport operator as its low-order approximation. Thus, in the acceleration step, the authors take advantage of features of the long-characteristics discretization that make it particularly well suited to assembly-level transport problems. The main contribution is to address difficulties unique to the long-characteristics discretization and produce a computationally efficient acceleration scheme. The combination of the long-characteristics discretization, opposing reflecting boundary conditions (which are present in assembly-level transport problems), and TSA presents several challenges. The authorsmore » devise methods for overcoming each of them in a computationally efficient way. Since the boundary angular data exist on different grids in the high- and low-order problems, they define restriction and prolongation operations specific to the method of long characteristics to map between the two grids. They implement the conjugate gradient (CG) method in the presence of opposing reflection boundary conditions to solve the TSA low-order equations. The CG iteration may be applied only to symmetric positive definite (SPD) matrices; they prove that the long-characteristics discretization yields an SPD matrix. They present results of the acceleration scheme on a simple test problem, a typical pressurized water reactor assembly, and a typical boiling water reactor assembly.« less

Controlling laser driven protons acceleration using a deformable mirror at a high repetition rate

NASA Astrophysics Data System (ADS)

Noaman-ul-Haq, M.; Sokollik, T.; Ahmed, H.; Braenzel, J.; Ehrentraut, L.; Mirzaie, M.; Yu, L.-L.; Sheng, Z. M.; Chen, L. M.; Schnürer, M.; Zhang, J.

2018-03-01

We present results from a proof-of-principle experiment to optimize laser driven protons acceleration by directly feeding back its spectral information to a deformable mirror (DM) controlled by evolutionary algorithms (EAs). By irradiating a stable high-repetition rate tape driven target with ultra-intense pulses of intensities ∼1020 W/ cm2, we optimize the maximum energy of the accelerated protons with a stability of less than ∼5% fluctuations near optimum value. Moreover, due to spatio-temporal development of the sheath field, modulations in the spectrum are also observed. Particularly, a prominent narrow peak is observed with a spread of ∼15% (FWHM) at low energy part of the spectrum. These results are helpful to develop high repetition rate optimization techniques required for laser-driven ion accelerators.

UNC EFRC: Fuels from Sunlight (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

ScienceCinema

Meyer, Thomas J. (Director, UNC EFRC: Solar Fuels and Next Generation Photovoltaics); UNC EFRC Staff

2017-12-09

'Fuels from Sunlight' was submitted by the University of North Carolina (UNC) EFRC: Solar Fuels and Next Generation Photovoltaics to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. The UNC EFRC directed by Thomas J. Meyer is a partnership of scientists from six institutions: UNC (lead), Duke University, University of Florida, North Caroline Central University, North Carolina State University, and the Research Triangle Institute. The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges. The mission of Solar Fuels and Next Generation Photovoltaics is 'to combine the best features of academic and translational research to study light/matter interactions and chemical processes for the efficient collection, transfer, and conversion of solar energy into chemical fuels and electricity.' Research topics are: catalysis (CO{sub 2}, hydrocarbons, water), electrocatalysis, photocatalysis, photoelectrocatalysis, solar photovoltaic, solar fuels, photonic, solar electrodes, photosynthesis, fuel cells, CO{sub 2} (convert), greenhosue gas, hydrogen (fuel), interfacial characterization, novel materials synthesis, charge transport, and self-assembly.

Mantle thermal history during supercontinent assembly and breakup

NASA Astrophysics Data System (ADS)

Rudolph, M. L.; Zhong, S.

2013-12-01

We use mantle convection simulations driven by plate motion boundary conditions to investigate changes in mantle temperature through time. It has been suggested that circum-Pangean subduction prevented convective thermal mixing between sub-continental and sub-oceanic regions. We performed thermo-chemical simulations of mantle convection with velocity boundary conditions based on plate motions for the past 450 Myr using Earth-like Rayleigh number and ~60% internal heating using three different plate motion models for the last 200 Myr [Lithgow-Bertelloni and Richards 1998; Gurnis et al. 2012; Seton et al. 2012; Zhang et al. 2010]. We quantified changes in upper-mantle temperature between 200-1000 km depth beneath continents (defined as the oldest 30% of Earth's surface) and beneath oceans. Sub-continental upper mantle temperature was relatively stable and high between 330 and 220 Ma, coincident with the existence of the supercontinent Pangea. The average sub-continental temperature during this period was, however, only ~10 K greater than during the preceding 100 Myr. In the ~200 Myr since the breakup of Pangea, sub-continental temperatures have decreased only ~15 K in excess of the 0.02 K/Myr secular cooling present in our models. Sub-oceanic upper mantle temperatures did not vary more than 5 K between 400 and 200 Ma and the cooling trend following Pangea breakup is less pronounced. Recent geochemical observations imply rapid upper mantle cooling of O(10^2) K during continental breakup; our models do not produce warming of this magnitude beneath Pangea or cooling of similar magnitude associated with the breakup of Pangea. Our models differ from those that produce strong sub-continental heating in that the circum-Pangean subduction curtain does not completely inhibit mixing between the sub-continental and sub-oceanic regions and we include significant internal heating, which limits the rate of temperature increase. Heat transport in our simulations is controlled to first order by plate motions. Most of the temporal variability in surface heat flow is driven by variations in seafloor spreading rate and the accompanying changes in slab velocities dominate variations in buoyancy flux at all mantle depths. Variations in plume buoyancy flux are small but are correlated with the slab buoyancy flux variations.

Biodiversity redistribution under climate change: Impacts on ecosystems and human well-being.

PubMed

Pecl, Gretta T; Araújo, Miguel B; Bell, Johann D; Blanchard, Julia; Bonebrake, Timothy C; Chen, I-Ching; Clark, Timothy D; Colwell, Robert K; Danielsen, Finn; Evengård, Birgitta; Falconi, Lorena; Ferrier, Simon; Frusher, Stewart; Garcia, Raquel A; Griffis, Roger B; Hobday, Alistair J; Janion-Scheepers, Charlene; Jarzyna, Marta A; Jennings, Sarah; Lenoir, Jonathan; Linnetved, Hlif I; Martin, Victoria Y; McCormack, Phillipa C; McDonald, Jan; Mitchell, Nicola J; Mustonen, Tero; Pandolfi, John M; Pettorelli, Nathalie; Popova, Ekaterina; Robinson, Sharon A; Scheffers, Brett R; Shaw, Justine D; Sorte, Cascade J B; Strugnell, Jan M; Sunday, Jennifer M; Tuanmu, Mao-Ning; Vergés, Adriana; Villanueva, Cecilia; Wernberg, Thomas; Wapstra, Erik; Williams, Stephen E

2017-03-31

Distributions of Earth's species are changing at accelerating rates, increasingly driven by human-mediated climate change. Such changes are already altering the composition of ecological communities, but beyond conservation of natural systems, how and why does this matter? We review evidence that climate-driven species redistribution at regional to global scales affects ecosystem functioning, human well-being, and the dynamics of climate change itself. Production of natural resources required for food security, patterns of disease transmission, and processes of carbon sequestration are all altered by changes in species distribution. Consideration of these effects of biodiversity redistribution is critical yet lacking in most mitigation and adaptation strategies, including the United Nation's Sustainable Development Goals. Copyright © 2017, American Association for the Advancement of Science.

Interaction of Energetic Particles with Discontinuities Upstream of Strong Shocks

NASA Astrophysics Data System (ADS)

Malkov, Mikhail; Diamond, Patrick

2008-11-01

Acceleration of particles in strong astrophysical shocks is known to be accompanied and promoted by a number of instabilities which are driven by the particles themselves. One of them is an acoustic (also known as Drury's) instability driven by the pressure gradient of accelerated particles upstream. The generated sound waves naturally steepen into shocks thus forming a shocktrain. Similar magnetoacoustic or Alfven type structures may be driven by pick-up ions, for example. We consider the solutions of kinetic equation for accelerated particles within the shocktrain. The accelerated particles are assumed to be coupled to the flow by an intensive pitch-angle scattering on the self-generated Alfven waves. The implications for acceleration and confinement of cosmic rays in this shock environment will be discussed.

Laser-driven electron beam and radiation sources for basic, medical and industrial sciences.

PubMed

Nakajima, Kazuhisa

2015-01-01

To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker's review article on "Laser Acceleration and its future" [Toshiki Tajima, (2010)],(1)) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated.

Demonstration of acceleration of relativistic electrons at a dielectric microstructure using femtosecond laser pulses

DOE PAGES

Wootton, Kent P.; Wu, Ziran; Cowan, Benjamin M.; ...

2016-06-02

Acceleration of electrons using laser-driven dielectric microstructures is a promising technology for the miniaturization of particle accelerators. Achieving the desired GV m –1 accelerating gradients is possible only with laser pulse durations shorter than ~1 ps. In this Letter, we present, to the best of our knowledge, the first demonstration of acceleration of relativistic electrons at a dielectric microstructure driven by femtosecond duration laser pulses. Furthermore, using this technique, an electron accelerating gradient of 690±100 MV m –1 was measured—a record for dielectric laser accelerators.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tan, Lun C.; Shao, Xi; Malandraki, Olga E., E-mail: ltan@umd.edu

We have examined 29 large solar energetic particle (SEP) events with the peak proton intensity J {sub pp}(>60 MeV) > 1 pfu during solar cycle 23. The emphasis of our examination is put on a joint analysis of Ne/O and Fe/O data in the energy range (3–40 MeV nucleon{sup −1}) covered by Wind /Low-Energy Matrix Telescope and ACE /Solar Isotope Spectrometer sensors in order to differentiate between the Fe-poor and Fe-rich events that emerged from the coronal mass ejection driven shock acceleration process. An improved ion ratio calculation is carried out by rebinning ion intensity data into the form ofmore » equal bin widths in the logarithmic energy scale. Through the analysis we find that the variability of Ne/O and Fe/O ratios can be used to investigate the accelerating shock properties. In particular, the high-energy Ne/O ratio is well correlated with the source plasma temperature of SEPs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kholodnaya, G. E.; Sazonov, R. V.; Ponomarev, D. V.

The paper presents the results of current measurements for the electron beam, propagating inside a drift tube filled in with a gas mixture (Ar and N{sub 2}). The experiments were performed using the TEA-500 pulsed electron accelerator. The main characteristics of electron beam were as follows: 60 ns pulse duration, up to 200 J energy, and 5 cm diameter. The electron beam propagated inside the drift tube assembled of three sections. Gas pressures inside the drift tube were 760 ± 3, 300 ± 3, and 50 ± 1 Torr. The studies were performed in argon, nitrogen, and their mixtures of 33%, 50%, and 66% volume concentrations, respectively.

High-quality electron beam generation in a proton-driven hollow plasma wakefield accelerator

NASA Astrophysics Data System (ADS)

Li, Y.; Xia, G.; Lotov, K. V.; Sosedkin, A. P.; Hanahoe, K.; Mete-Apsimon, O.

2017-10-01

Simulations of proton-driven plasma wakefield accelerators have demonstrated substantially higher accelerating gradients compared to conventional accelerators and the viability of accelerating electrons to the energy frontier in a single plasma stage. However, due to the strong intrinsic transverse fields varying both radially and in time, the witness beam quality is still far from suitable for practical application in future colliders. Here we demonstrate the efficient acceleration of electrons in proton-driven wakefields in a hollow plasma channel. In this regime, the witness bunch is positioned in the region with a strong accelerating field, free from plasma electrons and ions. We show that the electron beam carrying the charge of about 10% of 1 TeV proton driver charge can be accelerated to 0.6 TeV with a preserved normalized emittance in a single channel of 700 m. This high-quality and high-charge beam may pave the way for the development of future plasma-based energy frontier colliders.

Basic features of the STS/Spacelab vibration environment

NASA Technical Reports Server (NTRS)

Baugher, Charles R.; Ramachandran, N.

1994-01-01

The Space Shuttle acceleration environment is characterized. The acceleration environment is composed of a residual or quasi-steady component and higher frequency components induced by vehicle structural modes and the operation of onboard machinery. Quasi-steady accelerations are generally due to atmospheric drag, gravity gradient effects, and rotational forces. These accelerations tend to vary with the orbital frequency (approx. 10(exp -4) Hz) and have magnitudes less than or equal to 10(exp -6) g(sub 0) (where 1 g(sub 0) is terrestrial gravity). Higher frequency g-jitter is characterized by oscillatory disturbances in the 1-100 Hz range and transient components. Oscillatory accelerations are related to the response of large flexible structures like antennae, the Spacelab module, and the Orbiter itself, and to the operation of rotating machinery. The Orbiter structural modes in the 1-10 Hz range, are excited by oscillatory and transient disturbances and tend to dominate the energy spectrum of the acceleration environment. A comparison of the acceleration measurements from different Space Shuttle missions reveals the characteristic signature of the structural modes of the Orbiter overlaid with mission specific hardware induced disturbances and their harmonics. Transient accelerations are usually attributed to crew activity and Orbiter thruster operations. During crew sleep periods, the acceleration levels are typically on the order of 10(exp -6) g(sub 0) (1 micro-g). Crew work and exercise tend to raise the accelerations to the 10(exp -3) g(sub 0) (1 milli-g) level. Vernier reaction control system firings tend to cause accelerations of 10(exp -4) g(sub 0), while primary reaction control system and Orbiter maneuvering system firings cause accelerations as large as 10(exp -2) g(sub 0). Vibration isolation techniques (both active and passive systems) used during crew exercise have been shown to significantly reduce the acceleration magnitudes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu Shengwei; Yu Jiaguo

Bi{sub 2}WO{sub 6} hierarchical multilayered flower-like assemblies are fabricated on a large scale by a simple hydrothermal method in the presence of polymeric poly(sodium 4-styrenesulfonate). Such 3D Bi{sub 2}WO{sub 6} assemblies are constructed from orderly arranged 2D layers, which are further composed of a large number of interconnected nanoplates with a mean side length of ca. 50 nm. The bimodal mesopores associated with such hierarchical assembly exhibit peak mesopore size of ca. 4 nm for the voids within a layer, and peak mesopore size of ca. 40 nm corresponding to the interspaces between stacked layers, respectively. The formation process ismore » discussed on the basis of the results of time-dependent experiments, which support a novel 'coupled cooperative assembly and localized ripening' formation mechanism. More interestingly, we have noticed that the collective effect related to such hierarchical assembly induces a significantly enhanced optical absorbance in the UV-visible region. This work may shed some light on the design of complex architectures and exploitation of their potential applications. - Graphical abstract: Bi{sub 2}WO{sub 6} hierarchical multilayered flower-like assemblies are fabricated on a large scale by a simple hydrothermal method in the presence of polymeric poly(sodium 4-styrenesulfonate)« less

Rayleigh-Taylor mixing with time-dependent acceleration

NASA Astrophysics Data System (ADS)

Abarzhi, Snezhana

2016-10-01

We extend the momentum model to describe Rayleigh-Taylor (RT) mixing driven by a time-dependent acceleration. The acceleration is a power-law function of time, similarly to astrophysical and plasma fusion applications. In RT flow the dynamics of a fluid parcel is driven by a balance per unit mass of the rates of momentum gain and loss. We find analytical solutions in the cases of balanced and imbalanced gains and losses, and identify their dependence on the acceleration exponent. The existence is shown of two typical regimes of self-similar RT mixing-acceleration-driven Rayleigh-Taylor-type and dissipation-driven Richtymer-Meshkov-type with the latter being in general non-universal. Possible scenarios are proposed for transitions from the balanced dynamics to the imbalanced self-similar dynamics. Scaling and correlations properties of RT mixing are studied on the basis of dimensional analysis. Departures are outlined of RT dynamics with time-dependent acceleration from canonical cases of homogeneous turbulence as well as blast waves with first and second kind self-similarity. The work is supported by the US National Science Foundation.

Fuel cell sub-assembly

DOEpatents

Chi, Chang V.

1983-01-01

A fuel cell sub-assembly comprising a plurality of fuel cells, a first section of a cooling means disposed at an end of the assembly and means for connecting the fuel cells and first section together to form a unitary structure.

Micro-Masonry: Construction of 3D Structures by Mesoscale Self-Assembly

PubMed Central

Fernandez, Javier G.; Khademhosseini, Ali

2010-01-01

A general method for construction of three dimensional structures by directed assembly of microscale polymeric sub-units is presented. Shape-controlled microgels are directed to assemble into different shapes by limiting their movement onto a molded substrate. The capillary forces, resulting from the presence of a liquid polymer, assemble the microgels in close contact with the rest of the units and with the free surface, the latter imposing the final geometry of the resulting construct. The result is a freestanding structure composed of one or multiple layers of sub-units assembled in a tightly packed conformation. The applicability of the technique for the construction of scaffolds with cell-laden sub-units is demonstrated. In addition, scaffolds formed by the sequential aggregation of sub-units are produced. PMID:20440697

Development of new critical fluid-based processing methods for nutraceuticals and natural products

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, J. W.

2004-01-01

The development of new supercritical fluid processing technology as applied to nutraceuticals and natural products is no longer confined to using just supercritical fluid extraction (SFE) and supercritical carbon dioxide (SC-CO{sub 2}). Recently reported advances have been focused on modifying natural products and improving functionality of an end product using newer experimental techniques and fluid phases. In this presentation four focus areas will be emphasized: (1) control of particle size/morphology and encapsulation of the nutraceutical ingredients, (2) the use of combinatorial methodology to optimize critical fluid processing, (3) application of sub-critical water as a complementary medium for processing natural products,more » and (4) an assessment of the current state of products and processing which use critical fluid to produce nutraceutical and natural products for the food and cosmetic marketplace. Application of the various particle fomiation processes conducted in the presence of critical fluid media, such as: CPF, SAS, DELOS, RESS, PGSS, and GAS, can be used to produce particles of small and uniform distribution, having unique morphologies, that facilitate rapid dissolution or sustained release of many nutraceutical ingredients. These substances have included: therapeutic spices, phystosterols, vitamins, phospholpids, and carotenoids. Accelerating the development of critical fluid processing has been the application of combinatorial methodology to optimize extraction, fractionation, and/or reactions in near-, SC-, or subcritical fluid media. This is frequently accomplished by using sequential or multichannel automated instrumentation that was originally designed for analytical purposes. Several examples will be provided of rapidly assessing the extraction of anthocyanins with sub-critical water and the SFE of natural products. However, differences do exist in conducting experiments on the above instrumentation vs. scaled-up continuous processes, which will be noted. Sub-critical water is finding increase use as an extraction/fractionation or reaction medium. The literature reports applications for the extraction spices, natural antioxidants (rosemary, anthocyanins, etc.), and herbal components (tea and coffee ingredients), Our studies and the literature provide adequate correlations of solute solubility in sub-critical water as well as models for the kinetics of extraction in this medium. Finally, the current state of critical fluid technology as applied to natural products and nutraceuticals will be assessed; noting specific processes, organizations, and products that exist.« less

Petawatt pulsed-power accelerator

DOEpatents

Stygar, William A.; Cuneo, Michael E.; Headley, Daniel I.; Ives, Harry C.; Ives, legal representative; Berry Cottrell; Leeper, Ramon J.; Mazarakis, Michael G.; Olson, Craig L.; Porter, John L.; Wagoner; Tim C.

2010-03-16

A petawatt pulsed-power accelerator can be driven by various types of electrical-pulse generators, including conventional Marx generators and linear-transformer drivers. The pulsed-power accelerator can be configured to drive an electrical load from one- or two-sides. Various types of loads can be driven; for example, the accelerator can be used to drive a high-current z-pinch load. When driven by slow-pulse generators (e.g., conventional Marx generators), the accelerator comprises an oil section comprising at least one pulse-generator level having a plurality of pulse generators; a water section comprising a pulse-forming circuit for each pulse generator and a level of monolithic triplate radial-transmission-line impedance transformers, that have variable impedance profiles, for each pulse-generator level; and a vacuum section comprising triplate magnetically insulated transmission lines that feed an electrical load. When driven by LTD generators or other fast-pulse generators, the need for the pulse-forming circuits in the water section can be eliminated.

Anisotropic distribution function of minority tail ions generated by strong ion-cyclotron resonance heating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, C.S.; Colestock, P.

1989-05-01

The highly anisotropic particle distribution function of minority tail ions driven by ion-cyclotron resonance heating at the fundamental harmonic is calculated in a two-dimensional velocity space. It is assumed that the heating is strong enough to drive most of the resonant ions above the in-electron critical slowing-down energy. Simple analytic expressions for the tail distribution are obtained fro the case when the Doppler effect is sufficiently large to flatten the sharp pitch angle dependence in the bounce averaged qualilinear heating coefficient, D/sub b/, and for the case when D/sub b/ is assumed to be constant in pitch angle and energy.more » It is found that a simple constant-D/sub b/ solution can be used instead of the more complicated sharp-D/sub b/ solution for many analytic purposes. 4 refs., 4 figs.« less

Plasma wakefield acceleration experiments at FACET II

NASA Astrophysics Data System (ADS)

Joshi, C.; Adli, E.; An, W.; Clayton, C. E.; Corde, S.; Gessner, S.; Hogan, M. J.; Litos, M.; Lu, W.; Marsh, K. A.; Mori, W. B.; Vafaei-Najafabadi, N.; O'shea, B.; Xu, Xinlu; White, G.; Yakimenko, V.

2018-03-01

During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the ‘blow-out regime’ have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currently under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. We then briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider.

Plasma wakefield acceleration experiments at FACET II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, C.; Adli, E.; An, W.

During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the 'blow-out regime' have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currentlymore » under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. Here, we briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider.« less

Plasma wakefield acceleration experiments at FACET II

DOE PAGES

Joshi, C.; Adli, E.; An, W.; ...

2018-01-12

During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the 'blow-out regime' have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currentlymore » under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. Here, we briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider.« less

Stoichiometric Control of Multiple Different Tectons in Coordination-Driven Self-assembly

PubMed Central

Lee, Junseong; Ghosh, Koushik; Stang, Peter J.

2009-01-01

We present a general strategy for the synthesis of stable, multi-component fused polygon complexes where coordination-driven self-assembly allows for single supramolecular species can be formed from multi-component self-assembly and the shape of the obtained polygons can be controlled by simply changing the ratio of individual components. The compounds are characterized by Multinuclear NMR, ESI Mass spectrometry. PMID:19663439

Self-assembly of [UO{sub 2}X{sub 4}]{sup 2−} (X=Cl, Br) dianions with γ substituted pyridinium cations: Structural systematics and fluorescence properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Surbella, Robert G.; Andrews, Michael B.; Cahill, Christopher L., E-mail: cahill@gwu.edu

2016-04-15

Room temperature self-assembly of [UO{sub 2}X{sub 4}]{sup 2−} (X=Cl, Br) with γ substituted pyridinium cations has resulted in the formation of twelve compounds that were studied via single crystal X-ray diffraction and fluorescence spectroscopy. Systematic variation of electron donating groups on the pyridinium species is shown to influence the presence and/or strength of various supramolecular synthons, including hydrogen bonding and pi interactions. Combinations of such non-covalent interactions (NCIs) have given rise to a range of supramolecular assemblies, and are shown to influence uranyl emission by way of second sphere coordination to equatorial ligands. - Graphical abstract: Supramolecular assembly of themore » [UO{sub 2}Cl{sub 4}]{sup 2−} dianion with pyridinium cations is a viable synthetic route to the growth of uranyl containing single crystals.« less

Removable bearing arrangement for a wind turbine generator

DOEpatents

Bagepalli, Bharat Sampathkumaran; Jansen, Patrick Lee; Gadre, Aniruddha Dattatraya

2010-06-15

A wind generator having removable change-out bearings includes a rotor and a stator, locking bolts configured to lock the rotor and stator, a removable bearing sub-assembly having at least one shrunk-on bearing installed, and removable mounting bolts configured to engage the bearing sub-assembly and to allow the removable bearing sub-assembly to be removed when the removable mounting bolts are removed.

Method for changing removable bearing for a wind turbine generator

DOEpatents

Bagepalli, Bharat Sampathkumaran [Niskayuna, NY; Jansen, Patrick Lee , Gadre; Dattatraya, Aniruddha [Rexford, NY

2008-04-22

A wind generator having removable change-out bearings includes a rotor and a stator, locking bolts configured to lock the rotor and stator, a removable bearing sub-assembly having at least one shrunk-on bearing installed, and removable mounting bolts configured to engage the bearing sub-assembly and to allow the removable bearing sub-assembly to be removed when the removable mounting bolts are removed.

Can an attribution assessment be made for Yellow Rain? Systematic reanalysis in a chemical-and-biological-weapons use investigation.

PubMed

Katz, Rebecca; Singer, Burton

2007-03-01

In intelligence investigations, such as those into reports of chemical- or biological-weapons (CBW) use, evidence may be difficult to assemble and, once assembled, to weigh. We propose a methodology for such investigations and then apply it to a large body of recently declassified evidence to determine the extent to which an attribution can now be made in the Yellow Rain case. Our analysis strongly supports the hypothesis that CBW were used in Southeast Asia and Afghanistan in the late 1970s and early 1980s, although a definitive judgment cannot be made. The proposed methodology, while resource-intensive, allows evidence to be assembled and analyzed in a transparent manner so that assumptions and rationale for decisions can be challenged by external critics. We conclude with a discussion of future research directions, emphasizing the use of evolving information-extraction (IE) technologies, a sub-field of artificial intelligence (AI).

Laser-driven electron beam and radiation sources for basic, medical and industrial sciences

PubMed Central

NAKAJIMA, Kazuhisa

2015-01-01

To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker’s review article on “Laser Acceleration and its future” [Toshiki Tajima, (2010)],1) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated. PMID:26062737

Time-dependent simulation of oblique MHD cosmic-ray shocks using the two-fluid model

NASA Technical Reports Server (NTRS)

Frank, Adam; Jones, T. W.; Ryu, Dongsu

1995-01-01

Using a new, second-order accurate numerical method we present dynamical simulations of oblique MHD cosmic-ray (CR)-modified plane shock evolution. Most of the calculations are done with a two-fluid model for diffusive shock acceleration, but we provide also comparisons between a typical shock computed that way against calculations carried out using the more complete, momentum-dependent, diffusion-advection equation. We also illustrate a test showing that these simulations evolve to dynamical equilibria consistent with previously published steady state analytic calculations for such shocks. In order to improve understanding of the dynamical role of magnetic fields in shocks modified by CR pressure we have explored for time asymptotic states the parameter space of upstream fast mode Mach number, M(sub f), and plasma beta. We compile the results into maps of dynamical steady state CR acceleration efficiency, epsilon(sub c). We have run simulations using constant, and nonisotropic, obliquity (and hence spatially) dependent forms of the diffusion coefficient kappa. Comparison of the results shows that while the final steady states achieved are the same in each case, the history of CR-MHD shocks can be strongly modified by variations in kappa and, therefore, in the acceleration timescale. Also, the coupling of CR and MHD in low beta, oblique shocks substantially influences the transient density spike that forms in strongly CR-modified shocks. We find that inside the density spike a MHD slow mode wave can be generated that eventually steepens into a shock. A strong layer develops within the density spike, driven by MHD stresses. We conjecture that currents in the shear layer could, in nonplanar flows, results in enhanced particle accretion through drift acceleration.

The 7.5K lbf thrust engine preliminary design for Orbit Transfer Vehicle

NASA Technical Reports Server (NTRS)

Hayden, Warren R.; Sabiers, Ralph; Schneider, Judy

1994-01-01

This document summarizes the preliminary design of the Aerojet version of the Orbit Transfer Vehicle main engine. The concept of a 7500 lbf thrust LO2/GH2 engine using the dual expander cycle for optimum efficiency is validated through power balance and thermal calculations. The engine is capable of 10:1 throttling from a nominal 2000 psia to a 200 psia chamber pressure. Reservations are detailed on the feasibility of a tank head start, but the design incorporates low speed turbopumps to mitigate the problem. The mechanically separate high speed turbopumps use hydrostatic bearings to meet engine life requirements, and operate at sub-critical speed for better throttling ability. All components were successfully packaged in the restricted envelope set by the clearances for the extendible/retractable nozzle. Gimbal design uses an innovative primary and engine out gimbal system to meet the +/- 20 deg gimbal requirement. The hydrogen regenerator and LOX/GH2 heat exchanger uses the Aerojet platelet structures approach for a highly compact component design. The extendible/retractable nozzle assembly uses an electric motor driven jack-screw design and a one segment carbon-carbon or silicide coated columbium nozzle with an area ratio, when extended, of 1430:1. A reliability analysis and risk assessment concludes the report.

Self-assembly of microscopic chiplets at a liquid–liquid–solid interface forming a flexible segmented monocrystalline solar cell

PubMed Central

Knuesel, Robert J.; Jacobs, Heiko O.

2010-01-01

This paper introduces a method for self-assembling and electrically connecting small (20–60 micrometer) semiconductor chiplets at predetermined locations on flexible substrates with high speed (62500 chips/45 s), accuracy (0.9 micrometer, 0.14°), and yield (> 98%). The process takes place at the triple interface between silicone oil, water, and a penetrating solder-patterned substrate. The assembly is driven by a stepwise reduction of interfacial free energy where chips are first collected and preoriented at an oil-water interface before they assemble on a solder-patterned substrate that is pulled through the interface. Patterned transfer occurs in a progressing linear front as the liquid layers recede. The process eliminates the dependency on gravity and sedimentation of prior methods, thereby extending the minimal chip size to the sub-100 micrometer scale. It provides a new route for the field of printable electronics to enable the integration of microscopic high performance inorganic semiconductors on foreign substrates with the freedom to choose target location, pitch, and integration density. As an example we demonstrate a fault-tolerant segmented flexible monocrystalline silicon solar cell, reducing the amount of Si that is used when compared to conventional rigid cells. PMID:20080682

High power heating of magnetic reconnection in merging tokamak experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ono, Y.; Tanabe, H.; Gi, K.

2015-05-15

Significant ion/electron heating of magnetic reconnection up to 1.2 keV was documented in two spherical tokamak plasma merging experiment on MAST with the significantly large Reynolds number R∼10{sup 5}. Measured 1D/2D contours of ion and electron temperatures reveal clearly energy-conversion mechanisms of magnetic reconnection: huge outflow heating of ions in the downstream and localized heating of electrons at the X-point. Ions are accelerated up to the order of poloidal Alfven speed in the reconnection outflow region and are thermalized by fast shock-like density pileups formed in the downstreams, in agreement with recent solar satellite observations and PIC simulation results. The magneticmore » reconnection efficiently converts the reconnecting (poloidal) magnetic energy mostly into ion thermal energy through the outflow, causing the reconnection heating energy proportional to square of the reconnecting (poloidal) magnetic field B{sub rec}{sup 2}  ∼  B{sub p}{sup 2}. The guide toroidal field B{sub t} does not affect the bulk heating of ions and electrons, probably because the reconnection/outflow speeds are determined mostly by the external driven inflow by the help of another fast reconnection mechanism: intermittent sheet ejection. The localized electron heating at the X-point increases sharply with the guide toroidal field B{sub t}, probably because the toroidal field increases electron confinement and acceleration length along the X-line. 2D measurements of magnetic field and temperatures in the TS-3 tokamak merging experiment also reveal the detailed reconnection heating mechanisms mentioned above. The high-power heating of tokamak merging is useful not only for laboratory study of reconnection but also for economical startup and heating of tokamak plasmas. The MAST/TS-3 tokamak merging with B{sub p} > 0.4 T will enables us to heat the plasma to the alpha heating regime: T{sub i} > 5 keV without using any additional heating facility.« less

Subtidal hydrodynamics in a tropical lagoon: A dimensionless numbers approach

NASA Astrophysics Data System (ADS)

Tenorio-Fernandez, L.; Valle-Levinson, A.; Gomez-Valdes, J.

2018-01-01

Observations in a tropical lagoon of the Yucatan peninsula motivated a non-dimensional number analysis to examine the relative influence of tidal stress, density gradients and wind stress on subtidal hydrodynamics. A two-month observation period in Chelem Lagoon covered the transition from the dry to the wet season. Chelem Lagoon is influenced by groundwater inputs and exhibits a main sub-basin (central sub-basin), a west sub-basin and an east sub-basin. Subtidal hydrodynamics were associated with horizontal density gradients that were modified seasonally by evaporation, precipitation, and groundwater discharge. A tidal Froude number (Fr0), a Wedderburn number (W), and a Stress ratio (S0) were used to diagnose the relative importance of dominant subtidal driving forces. The Froude number (Fr0) compares tidal forcing and baroclinic forcing through the ratio of tidal stress to longitudinal baroclinic pressure gradient. The Wedderburn number (W) relates wind stress to baroclinicity. The stress ratio (S0) sizes tidal stress and wind stress. S0 is a new diagnostic tool for systems influenced by tides and winds, and represents the main contribution of this research. Results show that spring-tide subtidal flows in the tropical lagoon had log(Fr0) ≫ 0 and log(S0) > 0 , i.e., driven mainly by tidal stresses (advective accelerations). Neap tides showed log(Fr0) ≪ 0 and log(S0) < 0) , i.e., flows driven by baroclinicity, especially at the lagoon heads of the east and west sub-basins. However, when the wind stress intensified over the lagoon, the relative importance of baroclinicity decreased and the wind stress controlled the dynamics (log(W) ≫ 0). Each sub-basin exhibited a different subtidal response, according to the dimensionless numbers. The response depended on the fortnightly tidal cycle, the location and magnitude of groundwater input, and the direction and magnitude of the wind stress.

Magnetization, resistivity, specific heat and ab initio calculations of Gd₅Sb₃.

PubMed

Samatham, S Shanmukharao; Patel, Akhilesh Kumar; Lukoyanov, Alexey V; Suresh, K G

2018-06-07

We report on the combined results of structural, magnetic, transport and calorimetric properties of Mn₅Si₃-type hexagonal Gd₅Sb₃, together with <i>ab-initio</i> calculations. It exhibits a ferromagnetic (FM)-like transition at 265 K, antiferromagnetic (AFM) Néel transition at 95.5 K followed by a spin-orientation transition at 62 K. The system is found to be in AFM state down to 2 K in a field of 70 kOe. The FM-AFM phase coexistence is not noticeable despite large positive Curie-Weiss temperature (θ_CW = 223.5 ± 0.2 K). Instead, low-temperature AFM and high-temperature FM-like phases are separated in large temperatures. Temperature-magnetic field (<i>H</i>-<i>T</i>) phase diagram reveals field-driven complex magnetic phases. Within the AFM phase, the system is observed to undergo field-driven spin-orientation transitions. Field-induced tricritical and quantum critical points appear to be absent due to strong AFM nature and by the intervention of FM-like state between paramagnetic and AFM states, respectively. The metallic behavior of the compound is inferred from resistivity along with large Sommerfeld parameter. However, no sign of strong electron-correlations is reasoned from the Kadowaki-Wood's ratio <i>A</i>/γ² ∼ 1.9×10^-6 μΩ.cm.(mol.K)²(mJ)^-2, despite heavy γ. Essentially, <i>ab initio</i> calculations accounting for electronic correlations confirm AFM nature of low-temperature magnetic state in Gd₅Sb₃ and attainable FM ordering in agreement with experimental data. © 2018 IOP Publishing Ltd.

Response of Antarctic ice shelf melt to SAM trend and possible feedbacks with the ice-dynamics

NASA Astrophysics Data System (ADS)

Donat-Magnin, Marion; Jourdain, Nicolas C.; Gallée, Hubert; Spence, Paul; Cornford, Stephen L.; Le Sommer, Julien; Durand, Gaël

2017-04-01

The observed positive trend in the Southern Annular Mode (SAM) may warm the Southern Ocean sub-surface through decreased Ekman downward pumping. Subsequent change in ice-shelves melt has been suggested to trigger glacier acceleration in West Antarctica. Here we use a regional ocean model configuration of the Amundsen Sea that includes interactive ice-shelf cavities. Our results show that the inclusion of ice-shelves changes the ocean response to the projected SAM trend, i.e. it typically inhibits a part of the SAM-induced subsurface warming. Heat budget analysis has been used to propose responsible mechanisms. Regarding Thwaites and Pine Island, sub ice-shelf melt increases above 400m by approximately 40% for Thwaites and 10% for Pine Island and decreases by up to 10% below in response to ocean temperature changes driven by the projected SAM trend. The melt sensitivity to poleward shifting winds is nonetheless small compared to the sensitivity to an ice-sheet instability, i.e. to a projected change in the shape of ice-shelf cavities. For instance, the sub ice-shelf melt are doubled near the grounding line of some glaciers in response to the largest grounding line retreat projected for 2100. Large increase in basal melt close to the grounding line could largely impact instability and glacier acceleration. Our work suggests the need for including ice shelves into ocean models, and to couple ocean models to ice-sheet models in climate projections.

Orientational control of block copolymer microdomains by sub-tesla magnetic fields

NASA Astrophysics Data System (ADS)

Gopinadhan, Manesh; Choo, Youngwoo; Feng, Xunda; Kawabata, Kohsuke; di, Xiaojun; Osuji, Chinedum

Magnetic fields offer a versatile approach to controlling the orientation of block copolymer (BCP) microdomains during self-assembly. To date however, such control has required the imposition of large magnetic fields (>3T), necessitating the use of complex magnet systems - either superconducting or very large conventional resistive magnets. Here we demonstrate the ability to direct BCP self-assembly using considerably smaller fields (<1T) which are accessible using simple rare-earth permanent magnets. The low field alignment is enabled by the presence of small quantities of mesogenic species that are blended into, and co-assemble with the liquid crystalline (LC) mesophase of the side-chain LC BCP under study. In situ SAXS experiments reveal a pronounced dependence of the critical alignment field strength on the stoichiometry of the blend, and the ability to generate aligned microdomains with orientational distribution coefficients exceeding 0.95 at sub-1 T fields for appropriate stoichiometries. The alignment response overall can be rationalized in terms of increased mobility and grain size due to the presence of the mesogenic additive. We use a permanent magnet to fabricate films with aligned nanopores, and the utility of this approach to generate complex BCP microdomain patterns in thin films by local field screening are highlighted. NSF DMR-1410568 and DMR-0847534.

Two- and three-dimensional folding of thin film single-crystalline silicon for photovoltaic power applications

PubMed Central

Guo, Xiaoying; Li, Huan; Yeop Ahn, Bok; Duoss, Eric B.; Hsia, K. Jimmy; Lewis, Jennifer A.; Nuzzo, Ralph G.

2009-01-01

Fabrication of 3D electronic structures in the micrometer-to-millimeter range is extremely challenging due to the inherently 2D nature of most conventional wafer-based fabrication methods. Self-assembly, and the related method of self-folding of planar patterned membranes, provide a promising means to solve this problem. Here, we investigate self-assembly processes driven by wetting interactions to shape the contour of a functional, nonplanar photovoltaic (PV) device. A mechanics model based on the theory of thin plates is developed to identify the critical conditions for self-folding of different 2D geometrical shapes. This strategy is demonstrated for specifically designed millimeter-scale silicon objects, which are self-assembled into spherical, and other 3D shapes and integrated into fully functional light-trapping PV devices. The resulting 3D devices offer a promising way to efficiently harvest solar energy in thin cells using concentrator microarrays that function without active light tracking systems. PMID:19934059

Nanoscale assembly processes revealed in the nacroprismatic transition zone of Pinna nobilis mollusc shells

PubMed Central

Hovden, Robert; Wolf, Stephan E.; Holtz, Megan E.; Marin, Frédéric; Muller, David A.; Estroff, Lara A.

2015-01-01

Intricate biomineralization processes in molluscs engineer hierarchical structures with meso-, nano- and atomic architectures that give the final composite material exceptional mechanical strength and optical iridescence on the macroscale. This multiscale biological assembly inspires new synthetic routes to complex materials. Our investigation of the prism–nacre interface reveals nanoscale details governing the onset of nacre formation using high-resolution scanning transmission electron microscopy. A wedge-polishing technique provides unprecedented, large-area specimens required to span the entire interface. Within this region, we find a transition from nanofibrillar aggregation to irregular early-nacre layers, to well-ordered mature nacre suggesting the assembly process is driven by aggregation of nanoparticles (∼50–80 nm) within an organic matrix that arrange in fibre-like polycrystalline configurations. The particle number increases successively and, when critical packing is reached, they merge into early-nacre platelets. These results give new insights into nacre formation and particle-accretion mechanisms that may be common to many calcareous biominerals. PMID:26631940

Two- and three-dimensional folding of thin film single-crystalline silicon for photovoltaic power applications.

PubMed

Guo, Xiaoying; Li, Huan; Ahn, Bok Yeop; Duoss, Eric B; Hsia, K Jimmy; Lewis, Jennifer A; Nuzzo, Ralph G

2009-12-01

Fabrication of 3D electronic structures in the micrometer-to-millimeter range is extremely challenging due to the inherently 2D nature of most conventional wafer-based fabrication methods. Self-assembly, and the related method of self-folding of planar patterned membranes, provide a promising means to solve this problem. Here, we investigate self-assembly processes driven by wetting interactions to shape the contour of a functional, nonplanar photovoltaic (PV) device. A mechanics model based on the theory of thin plates is developed to identify the critical conditions for self-folding of different 2D geometrical shapes. This strategy is demonstrated for specifically designed millimeter-scale silicon objects, which are self-assembled into spherical, and other 3D shapes and integrated into fully functional light-trapping PV devices. The resulting 3D devices offer a promising way to efficiently harvest solar energy in thin cells using concentrator microarrays that function without active light tracking systems.

Determination of the magnetocaloric entropy change by field sweep using a heat flux setup

DOE Office of Scientific and Technical Information (OSTI.GOV)

Monteiro, J. C. B., E-mail: jolmiui@gmail.com; Reis, R. D. dos; Mansanares, A. M.

2014-08-18

We report on a simple setup using a heat flux sensor adapted to a Quantum Design Physical Property Measurement System to determine the magnetocaloric entropy change (ΔS). The major differences for the existing setups are the simplicity of this assembly and the ease to obtain the isothermal entropy change either by a field sweep or a temperature sweep process. We discuss the use of these two processes applied to Gd and Gd{sub 5}Ge{sub 2}Si{sub 2} samples. The results are compared to the temperature sweep measurements and they show the advantages of this setup and of the field sweep procedure. Wemore » found a significant reduction of ΔS and on the refrigerating cooling power (RCP) at low field changes in a field sweep process when the sample is not driven to the same initial state for each temperature. We show that the field sweep process without any measuring protocol is the only correct way to experimentally determine ΔS and RCP for a practical regenerative refrigerator.« less

On the hole accelerator for III-nitride light-emitting diodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Zi-Hui, E-mail: zh.zhang@hebut.edu.cn, E-mail: wbi@hebut.edu.cn, E-mail: volkan@stanfordalumni.org, E-mail: sunxw@sustc.edu.cn; Zhang, Yonghui; Bi, Wengang, E-mail: zh.zhang@hebut.edu.cn, E-mail: wbi@hebut.edu.cn, E-mail: volkan@stanfordalumni.org, E-mail: sunxw@sustc.edu.cn

2016-04-11

In this work, we systematically conduct parametric studies revealing the sensitivity of the hole injection on the hole accelerator (a hole accelerator is made of the polarization mismatched p-electron blocking layer (EBL)/p-GaN/p-Al{sub x}Ga{sub 1−x}N heterojunction) with different designs, including the AlN composition in the p-Al{sub x}Ga{sub 1−x}N layer, and the thickness for the p-GaN layer and the p-Al{sub x}Ga{sub 1−x}N layer. According to our findings, the energy that the holes obtain does not monotonically increase as the AlN incorporation in the p-Al{sub x}Ga{sub 1−x}N layer increases. Meanwhile, with p-GaN layer or p-Al{sub x}Ga{sub 1−x}N layer thickening, the energy that themore » holes gain increases and then reaches a saturation level. Thus, the hole injection efficiency and the device efficiency are very sensitive to the p-EBL/p-GaN/p-Al{sub x}Ga{sub 1−x}N design, and the hole accelerator can effectively increase the hole injection if properly designed.« less

Pilot Field Demonstration of Alternative Fuels in Force Projection Petroleum and Water Distribution Equipment

DTIC Science & Technology

2014-09-04

They included two Force Projection Technology (FPT) diesel driven pumping assemblies of 350 and 600 gallons per minute (GPM), and the Advanced...Army Tank Automotive Research Development and Engineering Center (TARDEC). They included two Force Projection Technology (FPT) diesel driven...research programs. The first two systems identified were Force Projection Technology (FPT) diesel -driven pumping assemblies of 350 and 600 gallons per

FORMATION OF SiC GRAINS IN PULSATION-ENHANCED DUST-DRIVEN WIND AROUND CARBON-RICH ASYMPTOTIC GIANT BRANCH STARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yasuda, Yuki; Kozasa, Takashi, E-mail: yuki@antares-a.sci.hokudai.ac.jp

2012-02-01

We investigate the formation of silicon carbide (SiC) grains in the framework of dust-driven wind around pulsating carbon-rich asymptotic giant branch (C-rich AGB) stars to reveal not only the amount but also the size distribution. Two cases are considered for the nucleation process: one is the local thermal equilibrium (LTE) case where the vibration temperature of SiC clusters T{sub v} is equal to the gas temperature as usual, and another is the non-LTE case in which T{sub v} is assumed to be the same as the temperature of small SiC grains. The results of the hydrodynamical calculations for a modelmore » with stellar parameters of mass M{sub *} = 1.0 M{sub Sun }, luminosity L{sub *} = 10{sup 4} L{sub Sun }, effective temperature T{sub eff} = 2600 K, C/O ratio = 1.4, and pulsation period P = 650 days show the following: in the LTE case, SiC grains condense in accelerated outflowing gas after the formation of carbon grains, and the resulting averaged mass ratio of SiC to carbon grains of {approx}10{sup -8} is too small to reproduce the value of 0.01-0.3, which is inferred from the radiative transfer models. On the other hand, in the non-LTE case, the formation region of the SiC grains is more internal and/or almost identical to that of the carbon grains due to the so-called inverse greenhouse effect. The mass ratio of SiC to carbon grains averaged at the outer boundary ranges from 0.098 to 0.23 for the sticking probability {alpha}{sub s} = 0.1-1.0. The size distributions with the peak at {approx}0.2-0.3 {mu}m in radius cover the range of size derived from the analysis of the presolar SiC grains. Thus, the difference between the temperatures of the small cluster and gas plays a crucial role in the formation process of SiC grains around C-rich AGB stars, and this aspect should be explored for the formation process of dust grains in astrophysical environments.« less

Applications of compact accelerator-driven neutron sources: An updated assessment from the perspective of materials research in Italy

DOE PAGES

Andreani, C.; Anderson, I. S.; Carpenter, J. M.; ...

2014-12-24

In 2005 the International Atomic Energy Agency (IAEA) in Vienna published a report [1] on ‘Development Opportunities of Small and Medium Scale Accelerator Driven Neutron Sources’ which summarized the prospect of smaller sources in supporting the large spallation neutron sources for materials characterization and instrumentation, a theme advocated by Bauer, Clausen, Mank, and Mulhauser in previous publications [2-4]. In 2010 the Union for Compact Accelerator-driven Neutron Sources (UCANS) was established [5], galvanizing cross-disciplinary collaborations on new source and neutronics development and expanded applications based on both slow-neutron scattering and other neutron-matter interactions of neutron energies ranging from 10⁻⁶ to 10²more » MeV [6]. Here, we first cover the recent development of ongoing and prospective projects of compact accelerator-driven neutron sources (CANS) but concentrate on prospective accelerators currently proposed in Italy. Two active R&D topics, irradiation effects on electronics and cultural heritage studies, are chosen to illustrate the impact of state-of-the-art CANS on these programs with respect to the characteristics and complementarity of the accelerator and neutronics systems as well as instrumentation development.« less

Beam shaping assembly optimization for (7)Li(p,n)(7)Be accelerator based BNCT.

PubMed

Minsky, D M; Kreiner, A J

2014-06-01

Within the framework of accelerator-based BNCT, a project to develop a folded Tandem-ElectroStatic-Quadrupole accelerator is under way at the Atomic Energy Commission of Argentina. The proposed accelerator is conceived to deliver a proton beam of 30mA at about 2.5MeV. In this work we explore a Beam Shaping Assembly (BSA) design based on the (7)Li(p,n)(7)Be neutron production reaction to obtain neutron beams to treat deep seated tumors. © 2013 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li Linzhi; Zhao Jingzhe, E-mail: zhaojz@hnu.edu.cn; Wang Yi

Tungsten oxide hydrate (WO{sub 3}.H{sub 2}O) nanoplates and flower-like assemblies were successfully synthesized via a simple aqueous method. The effects of reaction parameters in solution on the preparation were studied. Nanoplates and nanoflowers can be selectively prepared by changing the amount of H{sub 2}C{sub 2}O{sub 4}. In-situ assembly of nanoplates to nanoflowers was also proposed for the formation of assembled nanostructures. In addition, the reaction time and temperature have important effects on the sizes of the as-obtained samples. Crystal structure, morphology, and composition of final nanostructures were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Optical properties ofmore » the synthesized samples and the growth mechanism were studied by UV-vis detection. Degradation experiments of Rhodamine B (RhB) were also performed on samples of nanoplates and nanoflowers under visible light illumination. Nanoflower sample exhibited preferable photocatalytic property to nanoplate sample. - Graphical abstract: The oxalic acid has a key role for the structure of WO{sub 3}.H{sub 2}O evolution from plates to flowers and the dehydration process of WO{sub 3}.2H{sub 2}O to WO{sub 3}.H{sub 2}O. Highlights: > Tungsten oxides hydrate was synthesized via a simple aqueous method. > The size of WO{sub 3}.H{sub 2}O was controlled by the reaction time and temperature. > The assembly of WO{sub 3}.H{sub 2}O nanoplates to nanoflowers was achieved with higher H{sub 2}C{sub 2}O{sub 4}/Na{sub 2}WO{sub 4} ratio. > Oxalic acid has a key role in the dehydration process of WO{sub 3}.2H{sub 2}O to WO{sub 3}.H{sub 2}O.« less

Dogs lap using acceleration-driven open pumping

PubMed Central

Gart, Sean; Socha, John J.; Vlachos, Pavlos P.; Jung, Sunghwan

2015-01-01

Dogs lap because they have incomplete cheeks and cannot suck. When lapping, a dog’s tongue pulls a liquid column from the bath, suggesting that the hydrodynamics of column formation are critical to understanding how dogs drink. We measured lapping in 19 dogs and used the results to generate a physical model of the tongue’s interaction with the air–fluid interface. These experiments help to explain how dogs exploit the fluid dynamics of the generated column. The results demonstrate that effects of acceleration govern lapping frequency, which suggests that dogs curl the tongue to create a larger liquid column. Comparing lapping in dogs and cats reveals that, despite similar morphology, these carnivores lap in different physical regimes: an unsteady inertial regime for dogs and steady inertial regime for cats. PMID:26668382

Ablation driven by hot electrons generated during the ignitor laser pulse in shock ignition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piriz, A. R.; Rodriguez Prieto, G.; Tahir, N. A.

2012-12-15

An analytical model for the ablation driven by hot electrons is presented. The hot electrons are assumed to be generated during the high intensity laser spike used to produce the ignitor shock wave in the shock ignition driven inertial fusion concept, and to carry on the absorbed laser energy in its totality. Efficient energy coupling requires to keep the critical surface sufficiently close to the ablation front and this goal can be achieved for high laser intensities provided that the laser wavelength is short enough. Scaling laws for the ablation pressure and the other relevant magnitudes of the ablation cloudmore » are found in terms of the laser and target parameters. The effect of the preformed plasma assembled by the compression pulse, previous to the ignitor, is also discussed. It is found that a minimum ratio between the compression and the ignitor pulses would be necessary for the adequate matching of the corresponding scale lengths.« less

Laser-Driven Ion Acceleration from Plasma Micro-Channel Targets

PubMed Central

Zou, D. B.; Pukhov, A.; Yi, L. Q.; Zhou, H. B.; Yu, T. P.; Yin, Y.; Shao, F. Q.

2017-01-01

Efficient energy boost of the laser-accelerated ions is critical for their applications in biomedical and hadron research. Achiev-able energies continue to rise, with currently highest energies, allowing access to medical therapy energy windows. Here, a new regime of simultaneous acceleration of ~100 MeV protons and multi-100 MeV carbon-ions from plasma micro-channel targets is proposed by using a ~1020 W/cm2 modest intensity laser pulse. It is found that two trains of overdense electron bunches are dragged out from the micro-channel and effectively accelerated by the longitudinal electric-field excited in the plasma channel. With the optimized channel size, these “superponderomotive” energetic electrons can be focused on the front surface of the attached plastic substrate. The much intense sheath electric-field is formed on the rear side, leading to up to ~10-fold ionic energy increase compared to the simple planar geometry. The analytical prediction of the optimal channel size and ion maximum energies is derived, which shows good agreement with the particle-in-cell simulations. PMID:28218247

Laser-Driven Ion Acceleration from Plasma Micro-Channel Targets

NASA Astrophysics Data System (ADS)

Zou, D. B.; Pukhov, A.; Yi, L. Q.; Zhou, H. B.; Yu, T. P.; Yin, Y.; Shao, F. Q.

2017-02-01

Efficient energy boost of the laser-accelerated ions is critical for their applications in biomedical and hadron research. Achiev-able energies continue to rise, with currently highest energies, allowing access to medical therapy energy windows. Here, a new regime of simultaneous acceleration of ~100 MeV protons and multi-100 MeV carbon-ions from plasma micro-channel targets is proposed by using a ~1020 W/cm2 modest intensity laser pulse. It is found that two trains of overdense electron bunches are dragged out from the micro-channel and effectively accelerated by the longitudinal electric-field excited in the plasma channel. With the optimized channel size, these “superponderomotive” energetic electrons can be focused on the front surface of the attached plastic substrate. The much intense sheath electric-field is formed on the rear side, leading to up to ~10-fold ionic energy increase compared to the simple planar geometry. The analytical prediction of the optimal channel size and ion maximum energies is derived, which shows good agreement with the particle-in-cell simulations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wan Chan Tseung, Hok Seum, E-mail: wanchantseung.hok@mayo.edu; Ma, Jiasen; Kreofsky, Cole R.

Purpose: Our aim is to demonstrate the feasibility of fast Monte Carlo (MC)–based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. Methods and Materials: Recently, a fast and accurate graphics processor unit (GPU)–based MC simulation of proton transport was developed and used as the dose-calculation engine in a GPU-accelerated intensity modulated proton therapy (IMPT) optimizer. Besides dose, the MC can simultaneously score the dose-averaged linear energy transfer (LET{sub d}), which makes biological dose (BD) optimization possible. To convert from LET{sub d} to BD, a simple linear relation was assumed. By use of thismore » novel optimizer, inverse biological planning was applied to 4 patients, including 2 small and 1 large thyroid tumor targets, as well as 1 glioma case. To create these plans, constraints were placed to maintain the physical dose (PD) within 1.25 times the prescription while maximizing target BD. For comparison, conventional intensity modulated radiation therapy (IMRT) and IMPT plans were also created using Eclipse (Varian Medical Systems) in each case. The same critical-structure PD constraints were used for the IMRT, IMPT, and biologically optimized plans. The BD distributions for the IMPT plans were obtained through MC recalculations. Results: Compared with standard IMPT, the biologically optimal plans for patients with small tumor targets displayed a BD escalation that was around twice the PD increase. Dose sparing to critical structures was improved compared with both IMRT and IMPT. No significant BD increase could be achieved for the large thyroid tumor case and when the presence of critical structures mitigated the contribution of additional fields. The calculation of the biologically optimized plans can be completed in a clinically viable time (<30 minutes) on a small 24-GPU system. Conclusions: By exploiting GPU acceleration, MC-based, biologically optimized plans were created for small–tumor target patients. This optimizer will be used in an upcoming feasibility trial on LET{sub d} painting for radioresistant tumors.« less

Effects of Helium Ion Irradiation on Properties of Crystalline and Amorphous Multiphase Ceramic Coatings

NASA Astrophysics Data System (ADS)

Chen, Yong; Hu, Liangbin; Qiu, Changjun; He, Bin; Wang, Zhongchang

2017-08-01

The Al2O3-TiO2 crystalline and amorphous multiphase ceramic coatings were prepared on a martensitic steel by laser in situ reaction technique and impose irradiation with 200 keV He ions at different doses. The helium ion irradiation goes 1.55 μm deep from the surface of coating, and the displacement per atom (dpa) for the Al2O3-TiO2 coating is 20.0. When the irradiation fluency is 5 × 1017 ions/cm2, defects are identified in crystalline areas and there form interfacial areas in the coating. These crystal defects tend to migrate and converge at the interfaces. Moreover, helium ion irradiation is found to exert no effect on surface chemical composition and phase constitution of the coatings, while surface mechanical properties for the coatings after irradiation differ from those before irradiation. Further nano-indentation experiments reveal that surface nano-hardness of the Al2O3-TiO2 multiphase coatings decreases as the helium ions irradiation flux increases. Such Al2O3-TiO2 crystalline and amorphous multiphase ceramic coatings exhibit the strongest resistance against helium ion irradiation which shall be applied as candidate structural materials for accelerator-driven sub-critical system to handle the nuclear waste under extreme conditions.

Magnetic Control of Solutal Buoyancy Driven Convection

NASA Technical Reports Server (NTRS)

Ramachandran, N.; Leslie, F. W.

2003-01-01

Volumetric forces resulting from local density variations and gravitational acceleration cause buoyancy induced convective motion in melts and solutions. Solutal buoyancy is a result of concentration differences in an otherwise isothermal fluid. If the fluid also exhibits variations in magnetic susceptibility with concentration then convection control by external magnetic fields can be hypothesized. Magnetic control of thermal buoyancy induced convection in ferrofluids (dispersions of ferromagnetic particles in a carrier fluid) and paramagnetic fluids have been demonstrated. Here we show the nature of magnetic control of solutal buoyancy driven convection of a paramagnetic fluid, an aqueous solution of Manganese Chloride hydrate. We predict the critical magnetic field required for balancing gravitational solutal buoyancy driven convection and validate it through a simple experiment. We demonstrate that gravity driven flow can be completely reversed by a magnetic field but the exact cancellation of the flow is not possible. This is because the phenomenon is unstable. The technique can be applied to crystal growth processes in order to reduce convection and to heat exchanger devices for enhancing convection. The method can also be applied to impose a desired g-level in reduced gravity applications.

Plasma density characterization at SPARC_LAB through Stark broadening of Hydrogen spectral lines

NASA Astrophysics Data System (ADS)

Filippi, F.; Anania, M. P.; Bellaveglia, M.; Biagioni, A.; Chiadroni, E.; Cianchi, A.; Di Giovenale, D.; Di Pirro, G.; Ferrario, M.; Mostacci, A.; Palumbo, L.; Pompili, R.; Shpakov, V.; Vaccarezza, C.; Villa, F.; Zigler, A.

2016-09-01

Plasma-based acceleration techniques are of great interest for future, compact accelerators due to their high accelerating gradient. Both particle-driven and laser-driven Plasma Wakefield Acceleration experiments are foreseen at the SPARC_LAB Test Facility (INFN National Laboratories of Frascati, Italy), with the aim to accelerate high-brightness electron beams. In order to optimize the efficiency of the acceleration in the plasma and preserve the quality of the accelerated beam, the knowledge of the plasma electron density is mandatory. The Stark broadening of the Hydrogen spectral lines is one of the candidates used to characterize plasma density. The implementation of this diagnostic for plasma-based experiments at SPARC_LAB is presented.

Laser-driven particle acceleration for radiobiology and radiotherapy: where we are and where we are going

NASA Astrophysics Data System (ADS)

Giulietti, Antonio

2017-05-01

Radiation therapy of tumors progresses continuously and so do devices, sharing a global market of about $ 4 billions, growing at an annual rate exceeding 5%. Most of the progress involves tumor targeting, multi-beam irradiation, reduction of damage on healthy tissues and critical organs, dose fractioning. This fast-evolving scenario is the moving benchmark for the progress of the laser-based accelerators towards clinical uses. As for electrons, both energy and dose requested by radiotherapy are available with plasma accelerators driven by lasers in the power range of tens of TW but several issues have still to be faced before getting a prototype device for clinical tests. They include capability of varying electron energy, stability of the process, reliability for medical users. On the other side hadron therapy, presently applied to a small fraction of cases but within an exponential growth, is a primary option for the future. With such a strong motivation, research on laser-based proton/ion acceleration has been supported in the last decade in order to get performances suitable to clinical standards. None of these performances has been achieved so far with laser techniques. In the meantime a rich crop of data have been obtained in radiobiological experiments performed with beams of particles produced with laser techniques. It is quite significant however that most of the experiments have been performed moving bio samples to laser labs, rather moving laser equipment to bio labs or clinical contexts. This give us the measure that laser community cannot so far provide practical devices usable by non-laser people.

Lightwave-driven quasiparticle collisions on a sub-cycle timescale

PubMed Central

Langer, F.; Hohenleutner, M.; Schmid, C.; Poellmann, C.; Nagler, P.; Korn, T.; Schüller, C.; Sherwin, M. S.; Huttner, U.; Steiner, J. T.; Koch, S. W.; Kira, M.; Huber, R.

2016-01-01

Ever since Ernest Rutherford first scattered α-particles from gold foils1, collision experiments have revealed unique insights into atoms, nuclei, and elementary particles2. In solids, many-body correlations also lead to characteristic resonances3, called quasiparticles, such as excitons, dropletons4, polarons, or Cooper pairs. Their structure and dynamics define spectacular macroscopic phenomena, ranging from Mott insulating states via spontaneous spin and charge order to high-temperature superconductivity5. Fundamental research would immensely benefit from quasiparticle colliders, but the notoriously short lifetimes of quasiparticles6 have challenged practical solutions. Here we exploit lightwave-driven charge transport7–24, the backbone of attosecond science9–13, to explore ultrafast quasiparticle collisions directly in the time domain: A femtosecond optical pulse creates excitonic electron–hole pairs in the layered dichalcogenide tungsten diselenide while a strong terahertz field accelerates and collides the electrons with the holes. The underlying wave packet dynamics, including collision, pair annihilation, quantum interference and dephasing, are detected as light emission in high-order spectral sidebands17–19 of the optical excitation. A full quantum theory explains our observations microscopically. This approach opens the door to collision experiments with a broad variety of complex quasiparticles and suggests a promising new way of sub-femtosecond pulse generation. PMID:27172045

Sloshing dynamics modulated fluid angular momentum and moment fluctuations driven by orbital gravity gradient and jitter accelerations in microgravity

NASA Technical Reports Server (NTRS)

Hung, R. J.; Pan, H. L.

1995-01-01

The dynamical behavior of spacecraft propellant affected by the asymmetric combined gravity gradient and jitter accelerations, in particular the effect of surface tension on partially-filled rotating fluids applicable to a full-scale Gravity Probe-B Spacecraft dewar tank has been investigated. Three different cases of orbital accelerations: (1) gravity gradient-dominated, (2) equally weighted between gravity gradient and jitter, and (3) gravity jitter-dominated accelerations are studied. The results of slosh wave excitation along the liquid-vapor interface induced by gravity gradient-dominated accelerations provide a torsional moment with tidal motion of bubble oscillations in the rotating dewar. The results are clearly seen from the twisting shape of the bubble oscillations driven by gravity gradient-dominated acceleration. The results of slosh wave excitation along the liquid-vapor interface induced by gravity jitter-dominated acceleration indicate the results of bubble motion in a manner of down-and-up and leftward-and-rightward movement of oscillation when the bubble is rotating with respect to rotating dewar axis. Fluctuations of angular momentum, fluid moment and bubble mass center caused by slosh wave excitations driven by gravity gradient acceleration or gravity jitter acceleration are also investigated.

Stoichiometric control of multiple different tectons in coordination-driven self-assembly: preparation of fused metallacyclic polygons.

PubMed

Lee, Junseong; Ghosh, Koushik; Stang, Peter J

2009-09-02

We present a general strategy for the synthesis of stable, multicomponent fused polygon complexes in which coordination-driven self-assembly allows for single supramolecular species to be formed from multicomponent self-assembly and the shape of the obtained polygons can be controlled simply by changing the ratio of individual components. The compounds have been characterized by multinuclear NMR spectroscopy and electrospray ionization mass spectrometry.

Cell-free protein synthesis in micro compartments: building a minimal cell from biobricks.

PubMed

Jia, Haiyang; Heymann, Michael; Bernhard, Frank; Schwille, Petra; Kai, Lei

2017-10-25

The construction of a minimal cell that exhibits the essential characteristics of life is a great challenge in the field of synthetic biology. Assembling a minimal cell requires multidisciplinary expertise from physics, chemistry and biology. Scientists from different backgrounds tend to define the essence of 'life' differently and have thus proposed different artificial cell models possessing one or several essential features of living cells. Using the tools and methods of molecular biology, the bottom-up engineering of a minimal cell appears in reach. However, several challenges still remain. In particular, the integration of individual sub-systems that is required to achieve a self-reproducing cell model presents a complex optimization challenge. For example, multiple self-organisation and self-assembly processes have to be carefully tuned. We review advances and developments of new methods and techniques, for cell-free protein synthesis as well as micro-fabrication, for their potential to resolve challenges and to accelerate the development of minimal cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Passive Safety Features Evaluation of KIPT Neutron Source Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, Zhaopeng; Gohar, Yousry

2016-06-01

Argonne National Laboratory (ANL) of the United States and Kharkov Institute of Physics and Technology (KIPT) of Ukraine have cooperated on the development, design, and construction of a neutron source facility. The facility was constructed at Kharkov, Ukraine and its commissioning process is underway. It will be used to conduct basic and applied nuclear research, produce medical isotopes, and train young nuclear specialists. The facility has an electron accelerator-driven subcritical assembly. The electron beam power is 100 kW using 100 MeV electrons. Tungsten or natural uranium is the target material for generating neutrons driving the subcritical assembly. The subcritical assemblymore » is composed of WWR-M2 - Russian fuel assemblies with U-235 enrichment of 19.7 wt%, surrounded by beryllium reflector assembles and graphite blocks. The subcritical assembly is seated in a water tank, which is a part of the primary cooling loop. During normal operation, the water coolant operates at room temperature and the total facility power is ~300 KW. The passive safety features of the facility are discussed in in this study. Monte Carlo computer code MCNPX was utilized in the analyses with ENDF/B-VII.0 nuclear data libraries. Negative reactivity temperature feedback was consistently observed, which is important for the facility safety performance. Due to the design of WWR-M2 fuel assemblies, slight water temperature increase and the corresponding water density decrease produce large reactivity drop, which offset the reactivity gain by mistakenly loading an additional fuel assembly. The increase of fuel temperature also causes sufficiently large reactivity decrease. This enhances the facility safety performance because fuel temperature increase provides prompt negative reactivity feedback. The reactivity variation due to an empty fuel position filled by water during the fuel loading process is examined. Also, the loading mistakes of removing beryllium reflector assemblies and replacing them with dummy assemblies were analyzed. In all these circumstances, the reactivity change results do not cause any safety concerns.« less

Plasma Radiation and Acceleration Effectiveness of CME-driven Shocks

NASA Astrophysics Data System (ADS)

Gopalswamy, N.; Schmidt, J. M.

2008-05-01

CME-driven shocks are effective radio radiation generators and accelerators for Solar Energetic Particles (SEPs). We present simulated 3 D time-dependent radio maps of second order plasma radiation generated by CME- driven shocks. The CME with its shock is simulated with the 3 D BATS-R-US CME model developed at the University of Michigan. The radiation is simulated using a kinetic plasma model that includes shock drift acceleration of electrons and stochastic growth theory of Langmuir waves. We find that in a realistic 3 D environment of magnetic field and solar wind outflow of the Sun the CME-driven shock shows a detailed spatial structure of the density, which is responsible for the fine structure of type II radio bursts. We also show realistic 3 D reconstructions of the magnetic cloud field of the CME, which is accelerated outward by magnetic buoyancy forces in the diverging magnetic field of the Sun. The CME-driven shock is reconstructed by tomography using the maximum jump in the gradient of the entropy. In the vicinity of the shock we determine the Alfven speed of the plasma. This speed profile controls how steep the shock can grow and how stable the shock remains while propagating away from the Sun. Only a steep shock can provide for an effective particle acceleration.

Plasma radiation and acceleration effectiveness of CME-driven shocks

NASA Astrophysics Data System (ADS)

Schmidt, Joachim

CME-driven shocks are effective radio radiation generators and accelerators for Solar Energetic Particles (SEPs). We present simulated 3 D time-dependent radio maps of second order plasma radiation generated by CME-driven shocks. The CME with its shock is simulated with the 3 D BATS-R-US CME model developed at the University of Michigan. The radiation is simulated using a kinetic plasma model that includes shock drift acceleration of electrons and stochastic growth theory of Langmuir waves. We find that in a realistic 3 D environment of magnetic field and solar wind outflow of the Sun the CME-driven shock shows a detailed spatial structure of the density, which is responsible for the fine structure of type II radio bursts. We also show realistic 3 D reconstructions of the magnetic cloud field of the CME, which is accelerated outward by magnetic buoyancy forces in the diverging magnetic field of the Sun. The CME-driven shock is reconstructed by tomography using the maximum jump in the gradient of the entropy. In the vicinity of the shock we determine the Alfven speed of the plasma. This speed profile controls how steep the shock can grow and how stable the shock remains while propagating away from the Sun. Only a steep shock can provide for an effective particle acceleration.

Assembly-Driven Metagenomics of a Hypersaline Microbial Ecosystem (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

ScienceCinema

Allen, Eric

2018-02-05

Eric Allen of Scripps and UC San Diego on Assembly-driven metagenomics of a hypersaline microbial ecosystem at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, CA.

Assembly-Driven Metagenomics of a Hypersaline Microbial Ecosystem (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allen, Eric

2013-03-01

Eric Allen of Scripps and UC San Diego on Assembly-driven metagenomics of a hypersaline microbial ecosystem at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, CA.

NBD-labelled phospholipid accelerates apolipoprotein C-II amyloid fibril formation but is not incorporated into mature fibrils

PubMed Central

Ryan, Timothy M.; Griffin, Michael D. W.; Bailey, Michael F.; Schuck, Peter; Howlett, Geoffrey J.

2014-01-01

Human apolipoprotein (apo) C-II is one of several lipid-binding proteins that self-assemble into fibrils and accumulate in disease-related amyloid deposits. A general characteristic of these amyloid deposits is the presence of lipids, known to modulate individual steps in amyloid fibril formation. ApoC-II fibril formation is activated by sub-micellar phospholipids but inhibited by micellar lipids. We examined the mechanism for the activation by sub-micellar lipids using the fluorescently-labelled, short-chain phospholipid, 1-dodecyl-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]-2-hydroxy-glycero-3-phosphocholine (NBD-lyso-12-PC). Addition of submicellar NBD-lyso-12-PC increased the rate of fibril formation by apoC-II approximately two-fold. Stopped flow kinetic analysis using fluorescence detection and low, non-fibril forming concentrations of apoC-II indicated NBD-Lyso-12-PC binds rapidly, in the millisecond timescale, followed by the slower formation of discrete apoC-II tetramers. Sedimentation velocity analysis showed NBD-Lyso-12-PC binds to both apoC-II monomers and tetramers at approximately 5 sites per monomer with an average dissociation constant of approximately 10 μM. Mature apoC-II fibrils formed in the presence of NBD-Lyso-12-PC were devoid of lipid indicating a purely catalytic role for sub-micellar lipids in the activation of apoC-II fibril formation. These studies demonstrate the catalytic potential of small amphiphilic molecules to control protein folding and fibril assembly pathways. PMID:21985034

Electron density and plasma dynamics of a colliding plasma experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiechula, J., E-mail: wiechula@physik.uni-frankfurt.de; Schönlein, A.; Iberler, M.

2016-07-15

We present experimental results of two head-on colliding plasma sheaths accelerated by pulsed-power-driven coaxial plasma accelerators. The measurements have been performed in a small vacuum chamber with a neutral-gas prefill of ArH{sub 2} at gas pressures between 17 Pa and 400 Pa and load voltages between 4 kV and 9 kV. As the plasma sheaths collide, the electron density is significantly increased. The electron density reaches maximum values of ≈8 ⋅ 10{sup 15} cm{sup −3} for a single accelerated plasma and a maximum value of ≈2.6 ⋅ 10{sup 16} cm{sup −3} for the plasma collision. Overall a raise of the plasma density by a factor ofmore » 1.3 to 3.8 has been achieved. A scaling behavior has been derived from the values of the electron density which shows a disproportionately high increase of the electron density of the collisional case for higher applied voltages in comparison to a single accelerated plasma. Sequences of the plasma collision have been taken, using a fast framing camera to study the plasma dynamics. These sequences indicate a maximum collision velocity of 34 km/s.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mugridge, Jeffrey; Fiedler, Dorothea; Raymond, Kenneth

A ferrocene-based biscatecholamide ligand was prepared and investigated for the formation of metal-ligand supramolecular assemblies with different metals. Reaction with Ge(IV) resulted in the formation of a variety of Ge{sub n}L{sub m} coordination complexes, including [Ge{sub 2}L{sub 3}]{sup 4-} and [Ge{sub 2}L{sub 2}({mu}-OMe){sub 2}]{sup 2-}. The ligand's ability to swivel about the ferrocenyl linker and adopt different conformations accounts for formation of many different Ge{sub n}L{sub m} species. This study demonstrates why conformational ligand rigidity is essential in the rational design and directed self-assembly of supramolecular complexes.

Influences of urea–glycerol mixtures as mixed mesopore-controlling agents on tailoring physicochemical properties and photocatalytic H{sub 2} production activity of sol–gel-derived mesoporous-assembled TiO{sub 2} nanocrystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sreethawong, Thammanoon, E-mail: sreethawongt@imre.a-star.edu.sg; Ngamsinlapasathian, Supachai, E-mail: wonone@hotmail.com; Yoshikawa, Susumu

2013-01-15

Graphical abstract: Display Omitted Highlights: ► Mesoporous-assembled TiO{sub 2} nanocrystals were synthesized by modified sol–gel process. ► Urea–glycerol mixtures were applied as mixed mesopore-controlling agents. ► Urea and glycerol contents affected physicochemical properties of synthesized TiO{sub 2}. ► Photocatalytic H{sub 2} production activity also depended on urea and glycerol contents. ► 75 mol% urea and 25 mol% glycerol yielded the most photocatalytically active TiO{sub 2}. -- Abstract: In this work, the mesoporous-assembled TiO{sub 2} nanocrystal photocatalysts were successfully synthesized by a sol–gel process with the aid of urea–glycerol mixtures used as mixed mesopore-controlling agents. The photocatalytic activity of the synthesizedmore » mesoporous-assembled TiO{sub 2} nanocrystal photocatalysts was investigated for hydrogen production from the water splitting reaction using methanol as a hole scavenger under UV light irradiation. The synthesized TiO{sub 2} nanocrystal photocatalysts were systematically characterized by TG–DTA, N{sub 2} adsorption–desorption, SEM, high resolution TEM, and XRD analyses. The characterization results showed that the well-controlled contents of urea and glycerol in a urea–glycerol mixture at 75 mol% urea and 25 mol% glycerol resulted in not only the most highly porous network (i.e. the highest specific surface area and total pore volume, and the smallest mean mesopore diameter), but also the smallest crystallite size of the synthesized TiO{sub 2} nanocrystal photocatalyst. The photocatalytic reaction results, hence, revealed a much superior photocatalytic hydrogen production activity of the mesoporous-assembled TiO{sub 2} nanocrystal synthesized with 75 mol% urea and 25 mol% glycerol to the other synthesized TiO{sub 2} nanocrystals, also being much higher than those of the commercially available P-25 TiO{sub 2} and ST-01 TiO{sub 2} powders.« less

A Josephson radiation comb generator.

PubMed

Solinas, P; Gasparinetti, S; Golubev, D; Giazotto, F

2015-07-20

We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation.

Novel high-energy physics studies using intense lasers and plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leemans, Wim P.; Bulanov, Stepan; Esarey, Eric

2015-06-29

In the framework of the project “Novel high-energy physics studies using intense lasers and plasmas” we conducted the study of ion acceleration and “flying mirrors” with high intensity lasers in order to develop sources of ion beams and high frequency radiation for different applications. Since some schemes of laser ion acceleration are also considered a good source of “flying mirrors”, we proposed to investigate the mechanisms of “mirror” formation. As a result we were able to study the laser ion acceleration from thin foils and near critical density targets. We identified several fundamental factors limiting the acceleration in the RPAmore » regime and proposed the target design to compensate these limitations. In the case of near critical density targets, we developed a concept for the laser driven ion source for the hadron therapy. Also we studied the mechanism of “flying mirror” generation during the intense laser interaction with thin solid density targets. As for the laser-based positron creation and capture we initially proposed to study different regimes of positron beam generation and positron beam cooling. Since the for some of these schemes a good quality electron beam is required, we studied the generation of ultra-low emittance electron beams. In order to understand the fundamental physics of high energy electron beam interaction with high intensity laser pulses, which may affect the efficient generation of positron beams, we studied the radiation reaction effects.« less

MeV electron acceleration at 1 kHz with <10 mJ laser pulses

NASA Astrophysics Data System (ADS)

Salehi, Fatholah; Goers, Andy; Hine, George; Feder, Linus; Kuk, Donghoon; Miao, Bo; Woodbury, Daniel; Kim, Ki-Yong; Milchberg, Howard

2017-01-01

We demonstrate laser driven acceleration of electrons to MeV-scale energies at 1 kHz repetition rate using <10 mJ pulses focused on near-critical density He and H2 gas jets. Using the H2 gas jet, electron acceleration to 0.5 MeV in 10 fC bunches was observed with laser pulse energy as low as 1.3 mJ. Increasing the pulse energy to 10 mJ, we measure 1pC charge bunches with >1 MeV energy for both He and H gas jets. Such a high repetition rate, high flux ultrafast source has immediate application to time resolved probing of matter for scientific, medical, or security applications, either using the electrons directly or using a high-Z foil converter to generate ultrafast γ-rays. This work is supported by the US Department of Energy, the National Science Foundation, and the Air Force Office of Scientific Research.

Beam distribution reconstruction simulation for electron beam probe

NASA Astrophysics Data System (ADS)

Feng, Yong-Chun; Mao, Rui-Shi; Li, Peng; Kang, Xin-Cai; Yin, Yan; Liu, Tong; You, Yao-Yao; Chen, Yu-Cong; Zhao, Tie-Cheng; Xu, Zhi-Guo; Wang, Yan-Yu; Yuan, You-Jin

2017-07-01

An electron beam probe (EBP) is a detector which makes use of a low-intensity and low-energy electron beam to measure the transverse profile, bunch shape, beam neutralization and beam wake field of an intense beam with small dimensions. While it can be applied to many aspects, we limit our analysis to beam distribution reconstruction. This kind of detector is almost non-interceptive for all of the beam and does not disturb the machine environment. In this paper, we present the theoretical aspects behind this technique for beam distribution measurement and some simulation results of the detector involved. First, a method to obtain a parallel electron beam is introduced and a simulation code is developed. An EBP as a profile monitor for dense beams is then simulated using the fast scan method for various target beam profiles, including KV distribution, waterbag distribution, parabolic distribution, Gaussian distribution and halo distribution. Profile reconstruction from the deflected electron beam trajectory is implemented and compared with the actual profile, and the expected agreement is achieved. Furthermore, as well as fast scan, a slow scan, i.e. step-by-step scan, is considered, which lowers the requirement for hardware, i.e. Radio Frequency deflector. We calculate the three-dimensional electric field of a Gaussian distribution and simulate the electron motion in this field. In addition, a fast scan along the target beam direction and slow scan across the beam are also presented, and can provide a measurement of longitudinal distribution as well as transverse profile simultaneously. As an example, simulation results for the China Accelerator Driven Sub-critical System (CADS) and High Intensity Heavy Ion Accelerator Facility (HIAF) are given. Finally, a potential system design for an EBP is described.

Imbalance in Fatty-Acid-Chain Length of Gangliosides Triggers Alzheimer Amyloid Deposition in the Precuneus

PubMed Central

Oikawa, Naoto; Matsubara, Teruhiko; Fukuda, Ryoto; Yasumori, Hanaki; Hatsuta, Hiroyuki; Murayama, Shigeo; Sato, Toshinori; Suzuki, Akemi; Yanagisawa, Katsuhiko

2015-01-01

Amyloid deposition, a crucial event of Alzheimer’s disease (AD), emerges in distinct brain regions. A key question is what triggers the assembly of the monomeric amyloid ß-protein (Aß) into fibrils in the regions. On the basis of our previous findings that gangliosides facilitate the initiation of Aß assembly at presynaptic neuritic terminals, we investigated how lipids, including gangliosides, cholesterol and sphingomyelin, extracted from synaptic plasma membranes (SPMs) isolated from autopsy brains were involved in the Aß assembly. We focused on two regions of the cerebral cortex; precuneus and calcarine cortex, one of the most vulnerable and one of the most resistant regions to amyloid deposition, respectively. Here, we show that lipids extracted from SPMs isolated from the amyloid-bearing precuneus, but neither the amyloid-free precuneus nor the calcarine cortex, markedly accelerate the Aß assembly in vitro. Through liquid chromatography-mass spectrometry of the lipids, we identified an increase in the ratio of the level of GD1b-ganglioside containing C20:0 fatty acid to that containing C18:0 as a cause of the enhanced Aß assembly in the precuneus. Our results suggest that the local glycolipid environment play a critical role in the initiation of Alzheimer amyloid deposition. PMID:25798597

Laser-ablation-based ion source characterization and manipulation for laser-driven ion acceleration

NASA Astrophysics Data System (ADS)

Sommer, P.; Metzkes-Ng, J.; Brack, F.-E.; Cowan, T. E.; Kraft, S. D.; Obst, L.; Rehwald, M.; Schlenvoigt, H.-P.; Schramm, U.; Zeil, K.

2018-05-01

For laser-driven ion acceleration from thin foils (∼10 μm–100 nm) in the target normal sheath acceleration regime, the hydro-carbon contaminant layer at the target surface generally serves as the ion source and hence determines the accelerated ion species, i.e. mainly protons, carbon and oxygen ions. The specific characteristics of the source layer—thickness and relevant lateral extent—as well as its manipulation have both been investigated since the first experiments on laser-driven ion acceleration using a variety of techniques from direct source imaging to knife-edge or mesh imaging. In this publication, we present an experimental study in which laser ablation in two fluence regimes (low: F ∼ 0.6 J cm‑2, high: F ∼ 4 J cm‑2) was applied to characterize and manipulate the hydro-carbon source layer. The high-fluence ablation in combination with a timed laser pulse for particle acceleration allowed for an estimation of the relevant source layer thickness for proton acceleration. Moreover, from these data and independently from the low-fluence regime, the lateral extent of the ion source layer became accessible.

Treatment planning capability assessment of a beam shaping assembly for accelerator-based BNCT.

PubMed

Herrera, M S; González, S J; Burlon, A A; Minsky, D M; Kreiner, A J

2011-12-01

Within the frame of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT) a theoretical study was performed to assess the treatment planning capability of different configurations of an optimized beam shaping assembly for such a facility. In particular this study aims at evaluating treatment plans for a clinical case of Glioblastoma. Copyright © 2011 Elsevier Ltd. All rights reserved.

Complex collective dynamics of active torque-driven colloids at interfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snezhko, Alexey

Modern self-assembly techniques aiming to produce complex structural order or functional diversity often rely on non-equilibrium conditions in the system. Light, electric, or magnetic fields are predominantly used to modify interaction profiles of colloidal particles during self-assembly or induce complex out-of-equilibrium dynamic ordering. The energy injection rate, properties of the environment are important control parameters that influence the outcome of active (dynamic) self-assembly. The current review is focused on a case of collective dynamics and self-assembly of particles with externally driven torques coupled to a liquid or solid interface. The complexity of interactions in such systems is further enriched bymore » strong hydrodynamic coupling between particles. Unconventionally ordered dynamic self-assembled patterns, spontaneous symmetry breaking phenomena, self-propulsion, and collective transport have been reported in torque-driven colloids. Some of the features of the complex collective behavior and dynamic pattern formation in those active systems have been successfully captured in simulations.« less

Application of the backward extrapolation method to pulsed neutron sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talamo, Alberto; Gohar, Yousry

We report particle detectors operated in pulse mode are subjected to the dead-time effect. When the average of the detector counts is constant over time, correcting for the dead-time effect is simple and can be accomplished by analytical formulas. However, when the average of the detector counts changes over time it is more difficult to take into account the dead-time effect. When a subcritical nuclear assembly is driven by a pulsed neutron source, simple analytical formulas cannot be applied to the measured detector counts to correct for the dead-time effect because of the sharp change of the detector counts overmore » time. This work addresses this issue by using the backward extrapolation method. The latter can be applied not only to a continuous (e.g. californium) external neutron source but also to a pulsed external neutron source (e.g. by a particle accelerator) driving a subcritical nuclear assembly. Finally, the backward extrapolation method allows to obtain from the measured detector counts both the dead-time value and the real detector counts.« less

Application of the backward extrapolation method to pulsed neutron sources

DOE PAGES

Talamo, Alberto; Gohar, Yousry

2017-09-23

We report particle detectors operated in pulse mode are subjected to the dead-time effect. When the average of the detector counts is constant over time, correcting for the dead-time effect is simple and can be accomplished by analytical formulas. However, when the average of the detector counts changes over time it is more difficult to take into account the dead-time effect. When a subcritical nuclear assembly is driven by a pulsed neutron source, simple analytical formulas cannot be applied to the measured detector counts to correct for the dead-time effect because of the sharp change of the detector counts overmore » time. This work addresses this issue by using the backward extrapolation method. The latter can be applied not only to a continuous (e.g. californium) external neutron source but also to a pulsed external neutron source (e.g. by a particle accelerator) driving a subcritical nuclear assembly. Finally, the backward extrapolation method allows to obtain from the measured detector counts both the dead-time value and the real detector counts.« less

Microfabricated electrospray emitter arrays with integrated extractor and accelerator electrodes for the propulsion of small spacecraft

NASA Astrophysics Data System (ADS)

Dandavino, S.; Ataman, C.; Ryan, C. N.; Chakraborty, S.; Courtney, D.; Stark, J. P. W.; Shea, H.

2014-07-01

Microfabricated electrospray thrusters could revolutionize the spacecraft industry by providing efficient propulsion capabilities to micro and nano satellites (1-100 kg). We present the modeling, design, fabrication and characterization of a new generation of devices, for the first time integrating in the fabrication process individual accelerator electrodes capable of focusing and accelerating the emitted sprays. Integrating these electrodes is a key milestone in the development of this technology; in addition to increasing the critical performance metrics of thrust, specific impulse and propulsive efficiency, the accelerators enable a number of new system features such as power tuning and thrust vectoring and balancing. Through microfabrication, we produced high density arrays (213 emitters cm-2) of capillary emitters, assembling them at wafer-level with an extractor/accelerator electrode pair separated by micro-sandblasted glass. Through IV measurements, we could confirm that acceleration could be decoupled from the extraction of the spray—an important element towards the flexibility of this technology. We present the largest reported internally fed microfabricated arrays operation, with 127 emitters spraying in parallel, for a total beam of 10-30 µA composed by 95% of ions. Effective beam focusing was also demonstrated, with plume half-angles being reduced from approximately 30° to 15° with 2000 V acceleration. Based on these results, we predict, with 3000 V acceleration, thrust per emitter of 38.4 nN, specific impulse of 1103 s and a propulsive efficiency of 22% with <1 mW/emitter power consumption.

Fission yeast Alp14 is a dose-dependent plus end–tracking microtubule polymerase

PubMed Central

Al-Bassam, Jawdat; Kim, Hwajin; Flor-Parra, Ignacio; Lal, Neeraj; Velji, Hamida; Chang, Fred

2012-01-01

XMAP215/Dis1 proteins are conserved tubulin-binding TOG-domain proteins that regulate microtubule (MT) plus-end dynamics. Here we show that Alp14, a XMAP215 orthologue in fission yeast, Schizosaccharomyces pombe, has properties of a MT polymerase. In vivo, Alp14 localizes to growing MT plus ends in a manner independent of Mal3 (EB1). alp14-null mutants display short interphase MTs with twofold slower assembly rate and frequent pauses. Alp14 is a homodimer that binds a single tubulin dimer. In vitro, purified Alp14 molecules track growing MT plus ends and accelerate MT assembly threefold. TOG-domain mutants demonstrate that tubulin binding is critical for function and plus end localization. Overexpression of Alp14 or only its TOG domains causes complete MT loss in vivo, and high Alp14 concentration inhibits MT assembly in vitro. These inhibitory effects may arise from Alp14 sequestration of tubulin and effects on the MT. Our studies suggest that Alp14 regulates the polymerization state of tubulin by cycling between a tubulin dimer–bound cytoplasmic state and a MT polymerase state that promotes rapid MT assembly. PMID:22696680

Process for Testing Compaction of a Swaged Heater for an Anode Sub-Assembly of a Hollow Cathode Assembly

NASA Technical Reports Server (NTRS)

Patterson, Michael J. (Inventor); Verhey, Timothy R. R. (Inventor); Soulas, George C. (Inventor)

2003-01-01

A process for testing compaction of a swaged heater for an anode sub-assembly of a Hollow Cathode Assembly (HCA), in which a test sample is cleaned, its mass measured before and after immersion in kerosene for 24 hours, and a compaction percentage calculated. A swaged heater is rejected if the compaction percentage exceeds 84%, plus or minus 4%.

A unified convention for biological assemblies with helical symmetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsai, Chung-Jung, E-mail: tsaic@mail.nih.gov; Nussinov, Ruth; Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978

A new representation of helical structure by four parameters, [n{sub 1}, n{sub 2}, twist, rise], is able to generate an entire helical construct from asymmetric units, including cases of helical assembly with a seam. Assemblies with helical symmetry can be conveniently formulated in many distinct ways. Here, a new convention is presented which unifies the two most commonly used helical systems for generating helical assemblies from asymmetric units determined by X-ray fibre diffraction and EM imaging. A helical assembly is viewed as being composed of identical repetitive units in a one- or two-dimensional lattice, named 1-D and 2-D helical systems,more » respectively. The unification suggests that a new helical description with only four parameters [n{sub 1}, n{sub 2}, twist, rise], which is called the augmented 1-D helical system, can generate the complete set of helical arrangements, including coverage of helical discontinuities (seams). A unified four-parameter characterization implies similar parameters for similar assemblies, can eliminate errors in reproducing structures of helical assemblies and facilitates the generation of polymorphic ensembles from helical atomic models or EM density maps. Further, guidelines are provided for such a unique description that reflects the structural signature of an assembly, as well as rules for manipulating the helical symmetry presentation.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo Zehua; Tang Xianzhu

Parallel transport of long mean-free-path plasma along an open magnetic field line is characterized by strong temperature anisotropy, which is driven by two effects. The first is magnetic moment conservation in a non-uniform magnetic field, which can transfer energy between parallel and perpendicular degrees of freedom. The second is decompressional cooling of the parallel temperature due to parallel flow acceleration by conventional presheath electric field which is associated with the sheath condition near the wall surface where the open magnetic field line intercepts the discharge chamber. To the leading order in gyroradius to system gradient length scale expansion, the parallelmore » transport can be understood via the Chew-Goldbeger-Low (CGL) model which retains two components of the parallel heat flux, i.e., q{sub n} associated with the parallel thermal energy and q{sub s} related to perpendicular thermal energy. It is shown that in addition to the effect of magnetic field strength (B) modulation, the two components (q{sub n} and q{sub s}) of the parallel heat flux play decisive roles in the parallel variation of the plasma profile, which includes the plasma density (n), parallel flow (u), parallel and perpendicular temperatures (T{sub Parallel-To} and T{sub Up-Tack }), and the ambipolar potential ({phi}). Both their profile (q{sub n}/B and q{sub s}/B{sup 2}) and the upstream values of the ratio of the conductive and convective thermal flux (q{sub n}/nuT{sub Parallel-To} and q{sub s}/nuT{sub Up-Tack }) provide the controlling physics, in addition to B modulation. The physics described by the CGL model are contrasted with those of the double-adiabatic laws and further elucidated by comparison with the first-principles kinetic simulation for a specific but representative flux expander case.« less

Modelling the behaviour of oxide fuels containing minor actinides with urania, thoria and zirconia matrices in an accelerator-driven system

NASA Astrophysics Data System (ADS)

Sobolev, V.; Lemehov, S.; Messaoudi, N.; Van Uffelen, P.; Aı̈t Abderrahim, H.

2003-06-01

The Belgian Nuclear Research Centre, SCK • CEN, is currently working on the pre-design of the multipurpose accelerator-driven system (ADS) MYRRHA. A demonstration of the possibility of transmutation of minor actinides and long-lived fission products with a realistic design of experimental fuel targets and prognosis of their behaviour under typical ADS conditions is an important task in the MYRRHA project. In the present article, the irradiation behaviour of three different oxide fuel mixtures, containing americium and plutonium - (Am,Pu,U)O 2- x with urania matrix, (Am,Pu,Th)O 2- x with thoria matrix and (Am,Y,Pu,Zr)O 2- x with inert zirconia matrix stabilised by yttria - were simulated with the new fuel performance code MACROS, which is under development and testing at the SCK • CEN. All the fuel rods were considered to be of the same design and sizes: annular fuel pellets, helium bounded with the stainless steel cladding, and a large gas plenum. The liquid lead-bismuth eutectic was used as coolant. Typical irradiation conditions of the hottest fuel assembly of the MYRRHA subcritical core were pre-calculated with the MCNPX code and used in the following calculations as the input data. The results of prediction of the thermo-mechanical behaviour of the designed rods with the considered fuels during three irradiation cycles of 90 EFPD are presented and discussed.

Current-driven plasma acceleration versus current-driven energy dissipation. I - Wave stability theory

NASA Technical Reports Server (NTRS)

Kelly, A. J.; Jahn, R. G.; Choueiri, E. Y.

1990-01-01

The dominant unstable electrostatic wave modes of an electromagnetically accelerated plasma are investigated. The study is the first part of a three-phase program aimed at characterizing the current-driven turbulent dissipation degrading the efficiency of Lorentz force plasma accelerators such as the MPD thruster. The analysis uses a kinetic theory that includes magnetic and thermal effects as well as those of an electron current transverse to the magnetic field and collisions, thus combining all the features of previous models. Analytical and numerical solutions allow a detailed description of threshold criteria, finite growth behavior, destabilization mechanisms and maximized-growth characteristics of the dominant unstable modes. The lower hybrid current-driven instability is implicated as dominant and was found to preserve its character in the collisional plasma regime.

Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling.

PubMed

McGuire, Christina M; Forgac, Michael

2018-06-08

The vacuolar H + -ATPase (V-ATPase) is an ATP-driven proton pump involved in many cellular processes. An important mechanism by which V-ATPase activity is controlled is the reversible assembly of its two domains, namely the peripheral V 1 domain and the integral V 0 domain. Although reversible assembly is conserved across all eukaryotic organisms, the signaling pathways controlling it have not been fully characterized. Here, we identify glucose starvation as a novel regulator of V-ATPase assembly in mammalian cells. During acute glucose starvation, the V-ATPase undergoes a rapid and reversible increase in assembly and activity as measured by lysosomal acidification. Because the V-ATPase has recently been implicated in the activation of AMP kinase (AMPK), a critical cellular energy sensor that is also activated upon glucose starvation, we compared the time course of AMPK activation and V-ATPase assembly upon glucose starvation. We observe that AMPK activation precedes increased V-ATPase activity. Moreover, the starvation-induced increase in V-ATPase activity and assembly are prevented by the AMPK inhibitor dorsomorphin. These results suggest that increased assembly and activity of the V-ATPase upon glucose starvation are dependent upon AMPK. We also find that the PI3K/Akt pathway, which has previously been implicated in controlling V-ATPase assembly in mammalian cells, also plays a role in the starvation-induced increase in V-ATPase assembly and activity. These studies thus identify a novel stimulus of V-ATPase assembly and a novel signaling pathway involved in regulating this process. The possible function of starvation-induced increase in lysosomal V-ATPase activity is discussed. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

Quasi-monoenergetic protons accelerated by laser radiation pressure and shocks in thin gaseous targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

He Minqing; Shao Xi; Liu Chuansheng

Recent experiments and simulations have demonstrated effective CO{sub 2} laser acceleration of quasi-monoenergetic protons from thick gaseous hydrogen target (of thickness tens of laser wavelengths) via hole boring and shock accelerations. We present here an alternative novel acceleration scheme by combining laser radiation pressure acceleration with shock acceleration of protons in a thin gaseous target of thickness several laser wavelengths. The laser pushes the thin gaseous plasma forward while compressing it with protons trapped in it. We demonstrated the combined acceleration with two-dimensional particle-in-cell simulation and obtained quasi-monoenergetic protons {approx}44 MeV in a gas target of thickness twice of themore » laser wavelength irradiated by circularly polarized CO{sub 2} laser with normalized laser amplitude a{sub 0}=10.« less

Rotational Motion of Axisymmetric Marangoni Swimmers

NASA Astrophysics Data System (ADS)

Rothstein, Jonathan; Uvanovic, Nick

2017-11-01

A series of experiments will be presented investigating the motion of millimeter-sized particles on the surface of water. The particles were partially coated with ethanol and carefully placed on a water interface in a series of Petri dishes with different diameters. High speed particle motion was driven by strong surface tension gradients as the ethanol slowly diffuses from the particles into the water resulting in a Marangoni flow. The velocity and acceleration of the particles where measured. In addition to straight line motion, the presence of the bounding walls of the circular Petri dish was found to induce an asymmetric, rotational motion of the axisymmetric Marangoni swimmers. The rotation rate and radius of curvature was found to be a function of the size of the Petri dish and the curvature of the air-water interface near the edge of the dish. For large Petri dishes or small particles, rotation motion was observed far from the bounding walls. In these cases, the symmetry break appears to be the result of the onset of votex shedding. Finally, multiple spherical particles were observed to undergo assembly driven by capillary forces followed by explosive disassembly.

Building macromolecular assemblies by information-driven docking: introducing the HADDOCK multibody docking server.

PubMed

Karaca, Ezgi; Melquiond, Adrien S J; de Vries, Sjoerd J; Kastritis, Panagiotis L; Bonvin, Alexandre M J J

2010-08-01

Over the last years, large scale proteomics studies have generated a wealth of information of biomolecular complexes. Adding the structural dimension to the resulting interactomes represents a major challenge that classical structural experimental methods alone will have difficulties to confront. To meet this challenge, complementary modeling techniques such as docking are thus needed. Among the current docking methods, HADDOCK (High Ambiguity-Driven DOCKing) distinguishes itself from others by the use of experimental and/or bioinformatics data to drive the modeling process and has shown a strong performance in the critical assessment of prediction of interactions (CAPRI), a blind experiment for the prediction of interactions. Although most docking programs are limited to binary complexes, HADDOCK can deal with multiple molecules (up to six), a capability that will be required to build large macromolecular assemblies. We present here a novel web interface of HADDOCK that allows the user to dock up to six biomolecules simultaneously. This interface allows the inclusion of a large variety of both experimental and/or bioinformatics data and supports several types of cyclic and dihedral symmetries in the docking of multibody assemblies. The server was tested on a benchmark of six cases, containing five symmetric homo-oligomeric protein complexes and one symmetric protein-DNA complex. Our results reveal that, in the presence of either bioinformatics and/or experimental data, HADDOCK shows an excellent performance: in all cases, HADDOCK was able to generate good to high quality solutions and ranked them at the top, demonstrating its ability to model symmetric multicomponent assemblies. Docking methods can thus play an important role in adding the structural dimension to interactomes. However, although the current docking methodologies were successful for a vast range of cases, considering the variety and complexity of macromolecular assemblies, inclusion of some kind of experimental information (e.g. from mass spectrometry, nuclear magnetic resonance, cryoelectron microscopy, etc.) will remain highly desirable to obtain reliable results.

Generation and application of ultrashort coherent mid-infrared electromagnetic radiation

NASA Astrophysics Data System (ADS)

Wandel, Scott

Particle accelerators are useful instruments that help address critical issues for the future development of nuclear energy. Current state-of-the-art accelerators based on conventional radio-frequency (rf) cavities are too large and expensive for widespread commercial use, and alternative designs must be considered for supplying relativistic beams to small-scale applications, including medical imaging, secu- rity screening, and scientific research in a university-scale laboratory. Laser-driven acceleration using micro-fabricated dielectric photonic structures is an attractive approach because such photonic microstructures can support accelerating fields that are 10 to 100 times higher than that of rf cavity-based accelerators. Dielectric laser accelerators (DLAs) use commercial lasers as a driving source, which are smaller and less expensive than the klystrons used to drive current rf-based accelerators. Despite the apparent need for compact and economical laser sources for laser-driven acceleration, the availability of suitable high-peak-power lasers that cover a broad spectral range is currently limited. To address the needs of several innovative acceleration mechanisms like DLA, it is proposed to develop a coherent source of mid-infrared (IR) electromagnetic radiation that can be implemented as a driving source of laser accelerators. The use of ultrashort mid-IR high peak power laser systems in various laser-driven acceleration schemes has shown the potential to greatly reduce the optical pump intensities needed to realize high acceleration gradients. The optical intensity needed to achieve a given ponderomotive potential is 25 times less when using a 5-mum mid-IR laser as compared to using a 1-mum near-IR solid-state laser. In addition, dielectric structure breakdown caused by multiphoton ionization can be avoided by using longer-wavelength driving lasers. Current mid-IR laser sources do not produce sufficiently short pulse durations, broad spectral bandwidths, or high energies as required by certain accelerator applications. The use of a high-peak-power mid-IR laser system in DLA could enable tabletop accelerators on the MeV to GeV scale for security scanners, medical therapy devices, and compact x-ray light sources. This dissertation reports on the design and construction of a simple and robust, short-pulse parametric source operating at a center wavelength of 5 mum. The design and construction of a high-energy, short-pulse 2-mum parametric source is also presented, which serves as a surrogate pumping source for the 5-mum source. An elegant method for mid-IR pulse characterization is demonstrated, which makes use of ubiquitous silicon photodetectors, traditionally reserved for the characterization of near-IR radiation. In addition, a dual-chirped parametric amplification technique is extended into the mid-IR spectral region, producing a bandwidth-tunable mid-IR source in a simple design without sacrificing conversion efficiency. The design and development of a compact single-shot mid-IR prism spectrometer is also reported, and its implementation in a number of condensed matter studies at the Linac Coherent Light Source (LCLS) at the Stanford Linear Accelerator Center is discussed. Rapid tuning and optimization of a high-energy parametric laser system using the mid-IR spectrometer is demonstrated, which significantly enhances the capabilities of performing optical measurements on superconducting materials using the LCLS instrument. All of the laser sources and optical technologies presented in this dissertation were developed using relatively simple designs to provide compact and cost-e ective systems to address some of the challenges facing accelerator and IR spectroscopy technologies. (Abstract shortened by ProQuest.).

SHORT-LIVED STAR-FORMING GIANT CLUMPS IN COSMOLOGICAL SIMULATIONS OF z Almost-Equal-To 2 DISKS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Genel, Shy; Genzel, Reinhard; Foerster Schreiber, Natascha M.

Many observed massive star-forming z Almost-Equal-To 2 galaxies are large disks that exhibit irregular morphologies, with Almost-Equal-To 1 kpc, Almost-Equal-To 10{sup 8}-10{sup 10}M{sub o-dot} clumps. We present the largest sample to date of high-resolution cosmological smoothed particle hydrodynamics simulations that zoom-in on the formation of individual M{sub *} Almost-Equal-To 10{sup 10.5}M{sub o-dot} galaxies in Almost-Equal-To 10{sup 12}M{sub o-dot} halos at z Almost-Equal-To 2. Our code includes strong stellar feedback parameterized as momentum-driven galactic winds. This model reproduces many characteristic features of this observed class of galaxies, such as their clumpy morphologies, smooth and monotonic velocity gradients, high gas fractions (f{submore » g} Almost-Equal-To 50%), and high specific star formation rates ({approx}>1 Gyr{sup -1}). In accord with recent models, giant clumps (M{sub clump} Almost-Equal-To (5 Multiplication-Sign 10{sup 8}-10{sup 9})M{sub o-dot}) form in situ via gravitational instabilities. However, the galactic winds are critical for their subsequent evolution. The giant clumps we obtain are short-lived and are disrupted by wind-driven mass loss. They do not virialize or migrate to the galaxy centers as suggested in recent work neglecting strong winds. By phenomenologically implementing the winds that are observed from high-redshift galaxies and in particular from individual clumps, our simulations reproduce well new observational constraints on clump kinematics and clump ages. In particular, the observation that older clumps appear closer to their galaxy centers is reproduced in our simulations, as a result of inside-out formation of the disks rather than inward clump migration.« less

Bending strength of delaminated aerospace composites.

PubMed

Kinawy, Moustafa; Butler, Richard; Hunt, Giles W

2012-04-28

Buckling-driven delamination is considered among the most critical failure modes in composite laminates. This paper examines the propagation of delaminations in a beam under pure bending. A pre-developed analytical model to predict the critical buckling moment of a thin sub-laminate is extended to account for propagation prediction, using mixed-mode fracture analysis. Fractography analysis is performed to distinguish between mode I and mode II contributions to the final failure of specimens. Comparison between experimental results and analysis shows agreement to within 5 per cent in static propagation moment for two different materials. It is concluded that static fracture is almost entirely driven by mode II effects. This result was unexpected because it arises from a buckling mode that opens the delamination. For this reason, and because of the excellent repeatability of the experiments, the method of testing may be a promising means of establishing the critical value of mode II fracture toughness, G(IIC), of the material. Fatigue testing on similar samples showed that buckled delamination resulted in a fatigue threshold that was over 80 per cent lower than the static propagation moment. Such an outcome highlights the significance of predicting snap-buckling moment and subsequent propagation for design purposes.

The effect of magnetic islands on Ion Temperature Gradient turbulence driven transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hill, P., E-mail: peter.hill@york.ac.uk; York Plasma Institute, Department of Physics, University of York, Heslington, York YO10 5DD; Hariri, F.

2015-04-15

In this work, we address the question of the influence of magnetic islands on the perpendicular transport due to steady-state ITG turbulence on the energy transport time scale. We demonstrate that turbulence can cross the separatrix and enhance the perpendicular transport across magnetic islands. As the perpendicular transport in the interior of the island sets the critical island size needed for growth of neoclassical tearing modes, this increased transport leads to a critical island size larger than that predicted from considering collisional conductivities, but smaller than that using anomalous effective conductivities. We find that on Bohm time scales, the turbulencemore » is able to re-establish the temperature gradient across the island for islands widths w ≲ λ{sub turb}, the turbulence correlation length. The reduction in the island flattening is estimated by comparison with simulations retaining only the perpendicular temperature and no turbulence. At intermediate island widths, comparable to λ{sub turb}, turbulence is able to maintain finite temperature gradients across the island.« less

Advanced Mirror Technology Development (AMTD) Project: Overview and Year 4 Accomplishments

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2016-01-01

The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature toward the next Technology Readiness Level (TRL) critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics and ultra-high-contrast observations of exoplanets. Key hardware accomplishments of 2015/16 are the successful low-temperature fusion of a 1.5-meter diameter ULE mirror that is a 1/3rd scale model of a 4-meter mirror and the initiation of polishing of a 1.2-meter Extreme-Lightweight Zerodur mirror. Critical to AMTD's success is an integrated team of scientists, systems engineers, and technologists; and a science-driven systems engineering approach.

Advanced Mirror Technology Development (AMTD) project: overview and year four accomplishments

NASA Astrophysics Data System (ADS)

Stahl, H. Philip

2016-07-01

The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature toward the next Technology Readiness Level (TRL) critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics and ultra-high-contrast observations of exoplanets. Key hardware accomplishments of 2015/16 are the successful low-temperature fusion of a 1.5-meter diameter ULE mirror that is a 1/3rd scale model of a 4-meter mirror and the initiation of polishing of a 1.2-meter Extreme-Lightweight Zerodur mirror. Critical to AMTD's success is an integrated team of scientists, systems engineers, and technologists; and a science-driven systems engineering approach.

Microstructure and optical properties of black chrome befor and after exposure to high temperatures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lampert, C.M.; Washburn, J.

1979-01-01

the chemical and microstructural stability of the CHROM-ONYX type of black chrome solar coating was investigated at different temperatures and atmospheres. This was done to give a better understanding of the mechanism of solar energy selectivity and its variability when subjected to short term heat treatments. The as-plated structure was found to consist of a suspension of metallic chromium particles within the size range of 100A in a amorphous oxide matrix. this assembly was in turn formed into larger particles within the size range of 0.05 to 0.30 microns. Short term high temperature heat treatments were used to simulate stagnationmore » conditions. Samples were annealed in both air and vacuum, which resulted in similar characteristics. Annealing in air appeared to mildly accelerate optical degradation at high temperatures. For short term heat treatments below 300/sup 0/C the reflective and microstructural properties appeared to be unchanged. By in situ vacuum annealing of the coating above 400/sup 0/C microscrystalline Cr/sub 2/O/sub 3/ was identified. By observation of diffraction patterns it was concluded that a-Cr/sub 2/O/sub 3/ was transformed into crystalline Cr/sub 2/O/sub 3/. The Cr/sub 2/O/sub 3/ phase continued to grow at higher temperatures at the expense of chromium content. At temperatures above 500/sup 0/C in vacuum, a new phase identified as Cr/sub 3/O/sub 4/ formed. It was found that black chrome failed optically between 500 to 600/sup 0/C for 1 hour heat treatments in both air and vacuum; also the coating heated in air failed mechanically by peeling at 600/sup 0/C.« less

Microstructure and optical properties of black chrome before and after exposure to high temperatures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lampert, C.M.; Washburn, J.

1979-01-01

The chemical and microstructural stability of the CHROM-ONYX type of black chrome solar coating was investigated at different temperatures and atmospheres. This was done to give a better understanding of the mechanism of solar energy selectivity and its variability when subjected to short term heat treatments. The as-plated structure was found to consist of a suspension of metallic chromium particles within the size range of 100A in an amorphous oxide matrix. This assembly was in turn formed into larger particles within the size range of 0.05-0.30 microns. Short term high temperature heat treatments were used to simulate stagnation conditions. Samplesmore » were annealed in both air and vacuum, which resulted in similar characteristics. Annealing in air appeared to mildly accelerate optical degradation at high temperatures. For short term heat treatments below 300/sup 0/C the reflective and microstructural properties appeared to be unchanged. By in situ vacuum annealing of the coating above 400/sup 0/C microcrystalline Cr/sub 2/O/sub 3/ was identified. By observation of diffraction patterns it was concluded that a-Cr/sub 2/O/sub 3/ was transformed into crystalline Cr/sub 2/O/sub 3/. The Cr/sub 2/O/sub 3/ phase continued to grow at higher temperatures at the expense of chromium content. At temperatures above 500/sup 0/C in vacuum, a new phase identified as NiCr/sub 2/O/sub 4/ formed. It was found that black chrome failed optically between 500-600/sup 0/C for 1 hour heat treatments in both air and vacuum; also the coating heated in air failed mechanically by peeling at 600/sup 0/C.« less

Frequency-Dependent Viscosity of Xenon Near the Critical Point

NASA Technical Reports Server (NTRS)

Berg, Robert F.; Moldover, Michael R.; Zimmerli, Gregory A.

1999-01-01

We used a novel, overdamped oscillator aboard the Space Shuttle to measure the viscosity eta of xenon near its critical density rho(sub c), and temperature T(sub c). In microgravity, useful data were obtained within 0.1 mK of T(sub c), corresponding to a reduced temperature t = (T -T(sub c))/T(sub c) = 3 x 10(exp -7). The data extend two decades closer to T(sub c) than the best ground measurements, and they directly reveal the expected power-law behavior eta proportional to t(sup -(nu)z(sub eta)). Here nu is the correlation length exponent, and our result for the small viscosity exponent is z(sub eta) = 0.0690 +/- 0.0006. (All uncertainties are one standard uncertainty.) Our value for z(sub eta) depends only weakly on the form of the viscosity crossover function, and it agrees with the value 0.067 +/- 0.002 obtained from a recent two-loop perturbation expansion. The measurements spanned the frequency range 2 Hz less than or equal to f less than or equal to 12 Hz and revealed viscoelasticity when t less than or equal to 10(exp -1), further from T(sub c) than predicted. The viscoelasticity scales as Af(tau), where tau is the fluctuation-decay time. The fitted value of the viscoelastic time-scale parameter A is 2.0 +/- 0.3 times the result of a one-loop perturbation calculation. Near T(sub c), the xenon's calculated time constant for thermal diffusion exceeded days. Nevertheless, the viscosity results were independent of the xenon's temperature history, indicating that the density was kept near rho(sub c), by judicious choices of the temperature vs. time program. Deliberately bad choices led to large density inhomogeneities. At t greater than 10(exp -5), the xenon approached equilibrium much faster than expected, suggesting that convection driven by microgravity and by electric fields slowly stirred the sample.

Recent advances in laser-driven neutron sources

NASA Astrophysics Data System (ADS)

Alejo, A.; Ahmed, H.; Green, A.; Mirfayzi, S. R.; Borghesi, M.; Kar, S.

2016-11-01

Due to the limited number and high cost of large-scale neutron facilities, there has been a growing interest in compact accelerator-driven sources. In this context, several potential schemes of laser-driven neutron sources are being intensively studied employing laser-accelerated electron and ion beams. In addition to the potential of delivering neutron beams with high brilliance, directionality and ultra-short burst duration, a laser-driven neutron source would offer further advantages in terms of cost-effectiveness, compactness and radiation confinement by closed-coupled experiments. Some of the recent advances in this field are discussed, showing improvements in the directionality and flux of the laser-driven neutron beams.

Superconducting cable-in-conduit low resistance splice

DOEpatents

Artman, Thomas A.

2003-06-24

A low resistance splice connects two cable-in-conduit superconductors to each other. Dividing collars for arranging sub-cable units from each conduit are provided, along with clamping collars for mating each sub-cable wire assembly to form mated assemblies. The mated assemblies ideally can be accomplished by way of splicing collar. The mated assemblies are cooled by way of a flow of coolant, preferably helium. A method for implementing such a splicing is also described.

Bearing assemblies, apparatuses, and motor assemblies using the same

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sexton, Timothy N.; Cooley, Craig H.; Knuteson, Cody W.

2015-12-29

Various embodiments of the invention relate to bearing assemblies, apparatuses and motor assemblies that include geometric features configured to impart a selected amount of heat transfer and/or hydrodynamic film formation. In an embodiment, a bearing assembly may include a plurality of superhard bearing pads distributed circumferentially about an axis. At least some of the plurality of superhard bearing pads may include a plurality of sub-superhard bearing elements defining a bearing surface. At least some of the plurality of sub-superhard bearing elements may be spaced from one another by one or more voids to impart a selected amount of heat transfermore » and hydrodynamic film formation thereon during operation. The bearing assembly may also include a support ring that carries the plurality of superhard bearing pads. In addition, at least a portion of the sub-superhard bearing elements may extend beyond the support ring.« less

From inflation to recent cosmic acceleration: the fermionic Elko field driving the evolution of the universe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pereira, S.H.; Guimarães, T.M., E-mail: shpereira@feg.unesp.br, E-mail: thiago.mogui@gmail.com

In this paper we construct the complete evolution of the universe driven by the mass dimension one dark spinor called Elko, starting with inflation, passing by the matter dominated era and finishing with the recent accelerated expansion. The dynamic of the fermionic Elko field with a symmetry breaking type potential can reproduce all phases of the universe in a natural and elegant way. The dynamical equations in general case and slow roll conditions in the limit H || m {sub pl} are also presented for the Elko system. Numerical analysis for the number of e-foldings during inflation, energy density aftermore » inflation and for present time and also the actual size of the universe are in good agreement with the standard model of cosmology. An interpretation of the inflationary phase as a result of Pauli exclusion principle is also possible if the Elko field is treated as an average value of its quantum analogue.« less

Time-resolved measurements with streaked diffraction patterns from electrons generated in laser plasma wakefield

NASA Astrophysics Data System (ADS)

He, Zhaohan; Nees, John; Hou, Bixue; Krushelnick, Karl; Thomas, Alec; Beaurepaire, Benoît; Malka, Victor; Faure, Jérôme

2013-10-01

Femtosecond bunches of electrons with relativistic to ultra-relativistic energies can be robustly produced in laser plasma wakefield accelerators (LWFA). Scaling the electron energy down to sub-relativistic and MeV level using a millijoule laser system will make such electron source a promising candidate for ultrafast electron diffraction (UED) applications due to the intrinsic short bunch duration and perfect synchronization with the optical pump. Recent results of electron diffraction from a single crystal gold foil, using LWFA electrons driven by 8-mJ, 35-fs laser pulses at 500 Hz, will be presented. The accelerated electrons were collimated with a solenoid magnetic lens. By applying a small-angle tilt to the magnetic lens, the diffraction pattern can be streaked such that the temporal evolution is separated spatially on the detector screen after propagation. The observable time window and achievable temporal resolution are studied in pump-probe measurements of photo-induced heating on the gold foil.

Medical Isotope Production Analyses In KIPT Neutron Source Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talamo, Alberto; Gohar, Yousry

Medical isotope production analyses in Kharkov Institute of Physics and Technology (KIPT) neutron source facility were performed to include the details of the irradiation cassette and the self-shielding effect. An updated detailed model of the facility was used for the analyses. The facility consists of an accelerator-driven system (ADS), which has a subcritical assembly using low-enriched uranium fuel elements with a beryllium-graphite reflector. The beryllium assemblies of the reflector have the same outer geometry as the fuel elements, which permits loading the subcritical assembly with different number of fuel elements without impacting the reflector performance. The subcritical assembly is drivenmore » by an external neutron source generated from the interaction of 100-kW electron beam with a tungsten target. The facility construction was completed at the end of 2015, and it is planned to start the operation during the year of 2016. It is the first ADS in the world, which has a coolant system for removing the generated fission power. Argonne National Laboratory has developed the design concept and performed extensive design analyses for the facility including its utilization for the production of different radioactive medical isotopes. 99Mo is the parent isotope of 99mTc, which is the most commonly used medical radioactive isotope. Detailed analyses were performed to define the optimal sample irradiation location and the generated activity, for several radioactive medical isotopes, as a function of the irradiation time.« less

Beamed neutron emission driven by laser accelerated light ions

NASA Astrophysics Data System (ADS)

Kar, S.; Green, A.; Ahmed, H.; Alejo, A.; Robinson, A. P. L.; Cerchez, M.; Clarke, R.; Doria, D.; Dorkings, S.; Fernandez, J.; Mirfayzi, S. R.; McKenna, P.; Naughton, K.; Neely, D.; Norreys, P.; Peth, C.; Powell, H.; Ruiz, J. A.; Swain, J.; Willi, O.; Borghesi, M.

2016-05-01

Highly anisotropic, beam-like neutron emission with peak flux of the order of 109 n/sr was obtained from light nuclei reactions in a pitcher-catcher scenario, by employing MeV ions driven by a sub-petawatt laser. The spatial profile of the neutron beam, fully captured for the first time by employing a CR39 nuclear track detector, shows a FWHM divergence angle of ˜ 70^\\circ , with a peak flux nearly an order of magnitude higher than the isotropic component elsewhere. The observed beamed flux of neutrons is highly favourable for a wide range of applications, and indeed for further transport and moderation to thermal energies. A systematic study employing various combinations of pitcher-catcher materials indicates the dominant reactions being d(p, n+p)1H and d(d,n)3He. Albeit insufficient cross-section data are available for modelling, the observed anisotropy in the neutrons’ spatial and spectral profiles is most likely related to the directionality and high energy of the projectile ions.

Neutron spectrum determination in a sub-critical assembly using the multi-disc neutron activation technique

NASA Astrophysics Data System (ADS)

Koseoglou, P.; Vagena, E.; Stoulos, S.; Manolopoulou, M.

2016-09-01

Neutron spectrum of the sub-critical nuclear assembly-reactor of Aristotle University of Thessaloniki was measured at three radial distances from the reactor core. The neutron activation technique was applied irradiating 15 thick foils - disc of various elements at each position. The data of 38 (n, γ), (n, p) and (n, α) reactions were analyzed for specific activity determination. Discs instead of foils were used due to the relevant low neutron flux, so the gamma self-absorption as well as the neutron self-shielding factors has been calculated using GEANT simulations in order to determine the activity induced. The specific activities calculated for all isotopes studied were the input to the SANDII code, which was built specifically for the neutron spectrum de-convolution when the neutron activation technique is used. For the optimization of the results a technique was applied in order to minimize the influence of the initial-"guessed" spectrum shape SANDII uses. The neutron spectrum estimated presents a peak in the regions of (i) thermal neutrons ranged between 0.001 and 1 eV peaking at neutron energy ∼0.1 eV and (ii) fast neutrons ranged between 0.1 and 20 MeV peaking at neutron energy ∼1.2 MeV. The reduction of thermal neutrons is higher than the fast one as the distance from the reactor core increases since thermal neutrons capture by natural U-fuel has higher cross section than the fast neutrons.

How stellar feedback simultaneously regulates star formation and drives outflows

NASA Astrophysics Data System (ADS)

Hayward, Christopher C.; Hopkins, Philip F.

2017-02-01

We present an analytic model for how momentum deposition from stellar feedback simultaneously regulates star formation and drives outflows in a turbulent interstellar medium (ISM). Because the ISM is turbulent, a given patch of ISM exhibits sub-patches with a range of surface densities. The high-density patches are 'pushed' by feedback, thereby driving turbulence and self-regulating local star formation. Sufficiently low-density patches, however, are accelerated to above the escape velocity before the region can self-adjust and are thus vented as outflows. When the gas fraction is ≳ 0.3, the ratio of the turbulent velocity dispersion to the circular velocity is sufficiently high that at any given time, of the order of half of the ISM has surface density less than the critical value and thus can be blown out on a dynamical time. The resulting outflows have a mass-loading factor (η ≡ dot{M}_{out}/M_{star }) that is inversely proportional to the gas fraction times the circular velocity. At low gas fractions, the star formation rate needed for local self-regulation, and corresponding turbulent Mach number, declines rapidly; the ISM is 'smoother', and it is actually more difficult to drive winds with large mass-loading factors. Crucially, our model predicts that stellar-feedback-driven outflows should be suppressed at z ≲ 1 in M⋆ ≳ 1010 M⊙ galaxies. This mechanism allows massive galaxies to exhibit violent outflows at high redshifts and then 'shut down' those outflows at late times, thereby enabling the formation of a smooth, extended thin stellar disc. We provide simple fitting functions for η that should be useful for sub-resolution and semi-analytic models.

Numerical study of neutron beam divergence in a beam-fusion scenario employing laser driven ions

NASA Astrophysics Data System (ADS)

Alejo, A.; Green, A.; Ahmed, H.; Robinson, A. P. L.; Cerchez, M.; Clarke, R.; Doria, D.; Dorkings, S.; Fernandez, J.; McKenna, P.; Mirfayzi, S. R.; Naughton, K.; Neely, D.; Norreys, P.; Peth, C.; Powell, H.; Ruiz, J. A.; Swain, J.; Willi, O.; Borghesi, M.; Kar, S.

2016-09-01

The most established route to create a laser-based neutron source is by employing laser accelerated, low atomic-number ions in fusion reactions. In addition to the high reaction cross-sections at moderate energies of the projectile ions, the anisotropy in neutron emission is another important feature of beam-fusion reactions. Using a simple numerical model based on neutron generation in a pitcher-catcher scenario, anisotropy in neutron emission was studied for the deuterium-deuterium fusion reaction. Simulation results are consistent with the narrow-divergence (∼ 70 ° full width at half maximum) neutron beam recently served in an experiment employing multi-MeV deuteron beams of narrow divergence (up to 30° FWHM, depending on the ion energy) accelerated by a sub-petawatt laser pulse from thin deuterated plastic foils via the Target Normal Sheath Acceleration mechanism. By varying the input ion beam parameters, simulations show that a further improvement in the neutron beam directionality (i.e. reduction in the beam divergence) can be obtained by increasing the projectile ion beam temperature and cut-off energy, as expected from interactions employing higher power lasers at upcoming facilities.

THE INNER STRUCTURE OF DWARF-SIZED HALOS IN WARM AND COLD DARK MATTER COSMOLOGIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

González-Samaniego, A.; Avila-Reese, V.; Colín, P.

2016-03-10

By means of N-body + hydrodynamic zoom-in simulations we study the evolution of the inner dark matter and stellar mass distributions of central dwarf galaxies formed in halos of virial masses M{sub v} = (2–3) × 10{sup 10} h{sup −1} M{sub ⊙} at z = 0, both in a warm dark matter (WDM) and cold dark matter (CDM) cosmology. The half-mode mass in the WDM power spectrum of our simulations is M{sub f} = 2 × 10{sup 10} h{sup −1} M{sub ⊙}. In the dark matter (DM) only simulations halo density profiles are well described by the Navarro–Frenk–White parametric fit in both cosmologies, though the WDM halos have concentrations lower bymore » factors of 1.5–2.0 than their CDM counterparts. In the hydrodynamic simulations, the effects of baryons significantly flatten the inner density, velocity dispersion, and pseudo phase space density profiles of the WDM halos but not of the CDM ones. The density slope, measured at ≈0.02R{sub v}, α{sub 0.02}, becomes shallow in periods of 2–5 Gyr in the WDM runs. We explore whether this flattening process correlates with the global star formation (SF), M{sub s}/M{sub v} ratio, gas outflow, and internal specific angular momentum histories. We do not find any clear trends, but when α{sub 0.02} is shallower than −0.5, M{sub s}/M{sub v} is always between 0.25% and 1%. We conclude that the main reason for the formation of the shallow core is the presence of strong gas mass fluctuations inside the inner halo, which are a consequence of the feedback driven by a very bursty and sustained SF history in shallow gravitational potentials. Our WDM halos, which assemble late and are less concentrated than the CDM ones, obey these conditions. There are also (rare) CDM systems with extended mass assembly histories that obey these conditions and form shallow cores. The dynamical heating and expansion processes behind the DM core flattening apply also to the stars in such a way that the stellar age and metallicity gradients of the dwarfs are softened, their stellar half-mass radii strongly grow with time, and their central surface densities decrease.« less

Use of incomplete energy recovery for the energy compression of large energy spread charged particle beams

DOEpatents

Douglas, David R [Newport News, VA; Benson, Stephen V [Yorktown, VA

2007-01-23

A method of energy recovery for RF-base linear charged particle accelerators that allows energy recovery without large relative momentum spread of the particle beam involving first accelerating a waveform particle beam having a crest and a centroid with an injection energy E.sub.o with the centroid of the particle beam at a phase offset f.sub.o from the crest of the accelerating waveform to an energy E.sub.full and then recovering the beam energy centroid a phase f.sub.o+Df relative to the crest of the waveform particle beam such that (E.sub.full-E.sub.o)(1+cos(f.sub.o+Df))>dE/2 wherein dE=the full energy spread, dE/2=the full energy half spread and Df=the wave form phase distance.

EGF Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival

PubMed Central

Mardin, Balca R.; Isokane, Mayumi; Cosenza, Marco R.; Krämer, Alwin; Ellenberg, Jan; Fry, Andrew M.; Schiebel, Elmar

2014-01-01

Summary Timely and accurate assembly of the mitotic spindle is critical for the faithful segregation of chromosomes and centrosome separation is a key step in this process. The timing of centrosome separation varies dramatically between cell types; however, the mechanisms responsible for these differences and its significance are unclear. Here, we show that activation of epidermal growth factor receptor (EGFR) signaling determines the timing of centrosome separation. Premature separation of centrosomes decreases the requirement for the major mitotic kinesin Eg5 for spindle assembly, accelerates mitosis and decreases the rate of chromosome missegregation. Importantly, EGF stimulation impacts upon centrosome separation and mitotic progression to different degrees in different cell lines. Cells with high EGFR levels fail to arrest in mitosis upon Eg5 inhibition. This has important implications for cancer therapy since cells with high centrosomal response to EGF are more susceptible to combinatorial inhibition of EGFR and Eg5. PMID:23643362

Achievable flatness in a large microwave power transmitting antenna

NASA Technical Reports Server (NTRS)

Ried, R. C.

1980-01-01

A dual reference SPS system with pseudoisotropic graphite composite as a representative dimensionally stable composite was studied. The loads, accelerations, thermal environments, temperatures and distortions were calculated for a variety of operational SPS conditions along with statistical considerations of material properties, manufacturing tolerances, measurement accuracy and the resulting loss of sight (LOS) and local slope distributions. A LOS error and a subarray rms slope error of two arc minutes can be achieved with a passive system. Results show that existing materials measurement, manufacturing, assembly and alignment techniques can be used to build the microwave power transmission system antenna structure. Manufacturing tolerance can be critical to rms slope error. The slope error budget can be met with a passive system. Structural joints without free play are essential in the assembly of the large truss structure. Variations in material properties, particularly for coefficient of thermal expansion from part to part, is more significant than actual value.

High-Resolution Structure of a Self-Assembly-Competent Form of a Hydrophobic Peptide Captured in a Soluble [beta]-Sheet Scaffold

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makabe, Koki; Biancalana, Matthew; Yan, Shude

2010-02-08

{beta}-Rich self-assembly is a major structural class of polypeptides, but still little is known about its atomic structures and biophysical properties. Major impediments for structural and biophysical studies of peptide self-assemblies include their insolubility and heterogeneous composition. We have developed a model system, termed peptide self-assembly mimic (PSAM), based on the single-layer {beta}-sheet of Borrelia outer surface protein A. PSAM allows for the capture of a defined number of self-assembly-like peptide repeats within a water-soluble protein, making structural and energetic studies possible. In this work, we extend our PSAM approach to a highly hydrophobic peptide sequence. We show that amore » penta-Ile peptide (Ile{sub 5}), which is insoluble and forms {beta}-rich self-assemblies in aqueous solution, can be captured within the PSAM scaffold in a form capable of self-assembly. The 1.1-{angstrom} crystal structure revealed that the Ile{sub 5} stretch forms a highly regular {beta}-strand within this flat {beta}-sheet. Self-assembly models built with multiple copies of the crystal structure of the Ile5 peptide segment showed no steric conflict, indicating that this conformation represents an assembly-competent form. The PSAM retained high conformational stability, suggesting that the flat {beta}-strand of the Ile{sub 5} stretch primed for self-assembly is a low-energy conformation of the Ile{sub 5} stretch and rationalizing its high propensity for self-assembly. The ability of the PSAM to 'solubilize' an otherwise insoluble peptide stretch suggests the potential of the PSAM approach to the characterization of self-assembling peptides.« less

Laser-driven magnetic reconnection in the multi-plasmoid regime

NASA Astrophysics Data System (ADS)

Totorica, Samuel; Abel, Tom; Fiuza, Frederico

2017-10-01

Magnetic reconnection is a promising candidate mechanism for accelerating the nonthermal particles associated with explosive astrophysical phenomena. Laboratory experiments are starting to probe multi-plasmoid regimes of relevance for particle acceleration. We have performed two- and three-dimensional particle-in-cell (PIC) simulations to explore particle acceleration for parameters relevant to laser-driven reconnection experiments. We have extended our previous work to explore particle acceleration in larger system sizes. Our results show the transition to plasmoid-dominated acceleration associated with the merging and contraction of plasmoids that further extend the maximum energy of the power-law tail of the particle distribution. Furthermore, we have modeled Coulomb collisions and will discuss the influence of collisionality on the plasmoid formation, dynamics, and particle acceleration.

A new route to prepare multiresponsive organogels from a block ionomer via charge-driven assembly.

PubMed

Zhang, Tao; Guo, Qipeng

2013-06-04

We report a novel route to prepare multiresponsive organogels through charge-driven assembly between a block ionomer and a diblock copolymer. The ionic complex aggregates to form spherical cores, which are connected by the middle block of the block ionomer to form gels. The organogels are responsive to acids, amines and salts.

Kinase programs spatiotemporally regulate gap junction assembly and disassembly: effects on wound repair

PubMed Central

Solan, Joell L.; Lampe, Paul D.

2016-01-01

Gap junctions are highly ordered plasma membrane domains that are constantly assembled, remodeled and turned over due to the short half-life of connexins, the integral membrane proteins that form gap junctions. Connexin 43 (Cx43), by far the most widely expressed connexin, is phosphorylated at multiple serine residues in the cytoplasmic, C-terminal region allowing for exquisite cellular control over gap junctional communication. This is evident during epidermal wounding where spatiotemporal changes in connexin expression occur as cells are instructed whether to die, proliferate or migrate to promote repair. Early gap junctional communication is required for initiation of keratinocyte migration, but accelerated Cx43 turnover is also critical for proper wound healing at later stages. These events are controlled via a "kinase program" where sequential phosphorylation of Cx43 leads to reductions in Cx43’s half-life and significant depletion of gap junctions from the plasma membrane within several hours. The complex regulation of gap junction assembly and turnover affords several steps where intervention might speed wound healing. PMID:26706150

Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair.

PubMed

Solan, Joell L; Lampe, Paul D

2016-02-01

Gap junctions are highly ordered plasma membrane domains that are constantly assembled, remodeled and turned over due to the short half-life of connexins, the integral membrane proteins that form gap junctions. Connexin 43 (Cx43), by far the most widely expressed connexin, is phosphorylated at multiple serine residues in the cytoplasmic, C-terminal region allowing for exquisite cellular control over gap junctional communication. This is evident during epidermal wounding where spatiotemporal changes in connexin expression occur as cells are instructed whether to die, proliferate or migrate to promote repair. Early gap junctional communication is required for initiation of keratinocyte migration, but accelerated Cx43 turnover is also critical for proper wound healing at later stages. These events are controlled via a "kinase program" where sequential phosphorylation of Cx43 leads to reductions in Cx43's half-life and significant depletion of gap junctions from the plasma membrane within several hours. The complex regulation of gap junction assembly and turnover affords several steps where intervention might speed wound healing. Copyright © 2015 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bi, G.; Liu, C.; Si, S.

This paper was focused on core design, neutronics evaluation and fuel cycle analysis for Thorium-Uranium Breeding Recycle in current PWRs, without any major change to the fuel lattice and the core internals, but substituting the UOX pellet with Thorium-based pellet. The fuel cycle analysis indicates that Thorium-Uranium Breeding Recycle is technically feasible in current PWRs. A 4-loop, 193-assembly PWR core utilizing 17 x 17 fuel assemblies (FAs) was taken as the model core. Two mixed cores were investigated respectively loaded with mixed reactor grade Plutonium-Thorium (PuThOX) FAs and mixed reactor grade {sup 233}U-Thorium (U{sub 3}ThOX) FAs on the basis ofmore » reference full Uranium oxide (UOX) equilibrium-cycle core. The UOX/PuThOX mixed core consists of 121 UOX FAs and 72 PuThOX FAs. The reactor grade {sup 233}U extracted from burnt PuThOX fuel was used to fabrication of U{sub 3}ThOX for starting Thorium-. Uranium breeding recycle. In UOX/U{sub 3}ThOX mixed core, the well designed U{sub 3}ThOX FAs with 1.94 w/o fissile uranium (mainly {sup 233}U) were located on the periphery of core as a blanket region. U{sub 3}ThOX FAs remained in-core for 6 cycles with the discharged burnup achieving 28 GWD/tHM. Compared with initially loading, the fissile material inventory in U{sub 3}ThOX fuel has increased by 7% via 1-year cooling after discharge. 157 UOX fuel assemblies were located in the inner of UOX/U{sub 3}ThOX mixed core refueling with 64 FAs at each cycle. The designed UOX/PuThOX and UOX/U{sub 3}ThOX mixed core satisfied related nuclear design criteria. The full core performance analyses have shown that mixed core with PuThOX loading has similar impacts as MOX on several neutronic characteristic parameters, such as reduced differential boron worth, higher critical boron concentration, more negative moderator temperature coefficient, reduced control rod worth, reduced shutdown margin, etc.; while mixed core with U{sub 3}ThOX loading on the periphery of core has no visible impacts on neutronic characteristics compared with reference full UOX core. The fuel cycle analysis has shown that {sup 233}U mono-recycling with U{sub 3}ThOX fuel could save 13% of natural uranium resource compared with UOX once through fuel cycle, slightly more than that of Plutonium single-recycling with MOX fuel. If {sup 233}U multi-recycling with U{sub 3}ThOX fuel is implemented, more natural uranium resource would be saved. (authors)« less

Betatron x-ray radiation from laser-plasma accelerators driven by femtosecond and picosecond laser systems

NASA Astrophysics Data System (ADS)

Albert, F.; Lemos, N.; Shaw, J. L.; King, P. M.; Pollock, B. B.; Goyon, C.; Schumaker, W.; Saunders, A. M.; Marsh, K. A.; Pak, A.; Ralph, J. E.; Martins, J. L.; Amorim, L. D.; Falcone, R. W.; Glenzer, S. H.; Moody, J. D.; Joshi, C.

2018-05-01

A comparative experimental study of betatron x-ray radiation from laser wakefield acceleration in the blowout and self-modulated regimes is presented. Our experiments use picosecond duration laser pulses up to 150 J (self-modulated regime) and 60 fs duration laser pulses up to 10 J (blowout regime), for plasmas with electronic densities on the order of 1019 cm-3. In the self-modulated regime, where betatron radiation has been very little studied compared to the blowout regime, electrons accelerated in the wake of the laser pulse are subject to both the longitudinal plasma and transverse laser electrical fields. As a result, their motion within the wake is relatively complex; consequently, the experimental and theoretical properties of the x-ray source based on self-modulation differ from the blowout regime of laser wakefield acceleration. In our experimental configuration, electrons accelerated up to about 250 MeV and betatron x-ray spectra with critical energies of about 10-20 keV and photon fluxes between 108 and 1010 photons/eV Sr are reported. Our experiments open the prospect of using betatron x-ray radiation for applications, and the source is competitive with current x-ray backlighting methods on multi-kilojoule laser systems.

RADIO DIAGNOSTICS OF ELECTRON ACCELERATION SITES DURING THE ERUPTION OF A FLUX ROPE IN THE SOLAR CORONA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carley, Eoin P.; Gallagher, Peter T.; Vilmer, Nicole, E-mail: eoin.carley@obspm.fr

Electron acceleration in the solar corona is often associated with flares and the eruption of twisted magnetic structures known as flux ropes. However, the locations and mechanisms of such particle acceleration during the flare and eruption are still subject to much investigation. Observing the exact sites of particle acceleration can help confirm how the flare and eruption are initiated and how they evolve. Here we use the Atmospheric Imaging Assembly to analyze a flare and erupting flux rope on 2014 April 18, while observations from the Nançay Radio Astronomy Facility allow us to diagnose the sites of electron acceleration duringmore » the eruption. Our analysis shows evidence of a pre-formed flux rope that slowly rises and becomes destabilized at the time of a C-class flare, plasma jet, and the escape of ≳75 keV electrons from the rope center into the corona. As the eruption proceeds, continued acceleration of electrons with energies of ∼5 keV occurs above the flux rope for a period over 5 minutes. At the flare peak, one site of electron acceleration is located close to the flare site, while another is driven by the erupting flux rope into the corona at speeds of up to 400 km s{sup −1}. Energetic electrons then fill the erupting volume, eventually allowing the flux rope legs to be clearly imaged from radio sources at 150–445 MHz. Following the analysis of Joshi et al. (2015), we conclude that the sites of energetic electrons are consistent with flux rope eruption via a tether cutting or flux cancellation scenario inside a magnetic fan-spine structure. In total, our radio observations allow us to better understand the evolution of a flux rope eruption and its associated electron acceleration sites, from eruption initiation to propagation into the corona.« less

Improving Self-Assembly by Varying the Temperature Periodically with Time

NASA Astrophysics Data System (ADS)

Raz, Oren; Jarzynski, Christopher

Self-assembly (SA) is the process by which basic components organize into a larger structure without external guidance. These processes are common in Nature, and also have technological applications, e.g. growing a crystal with a specific structure. So far, artificial SA processes have been designed mostly using diffusive building blocks with high specificity and directionality. The formation of the self-assembled structures is then driven by free-energy minimization into a thermodynamically stable state. In an alternative approach to SA, macroscopic parameters such as temperature, pressure, pH, magnetic field etc., are varied periodically with time. In this case, the SA structures are the stable periodic states of the driven system. Currently there are no design principles for periodically driven SA, other than in the limits of fast or weak driving. We present guiding ideas for self-assembly under periodic driving. As an example, we show a particular case in which self-assembly errors can be dramatically reduced by varying a system's temperature periodically with time. James S. McDonnell Foundation, and the US National Science Foundation: DMR-1506969.

Transmission of cluster ions through a tandem accelerator of several stripper gases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saitoh, Yuichi; Chiba, Atsuya; Narumi, Kazumasa

2009-10-15

The transmissions of carbon cluster ion beams through a tandem accelerator using several stripper gases (He, N{sub 2}, CO{sub 2}, and SF{sub 6}) with a terminal voltage of 2.5 MV were measured as a function of the gas pressure in investigating the most suitable gas for cluster ion acceleration. This resulted in it being demonstrated that the highest transmission could be obtained using the smaller size gas, i.e., helium displayed the best performance of the four gases used. In addition, the ratio of transmissions of C{sub n} with helium and nitrogen increased with increases in the n, thus revealing thatmore » helium gas should prove the most effective in larger cluster ion acceleration using the same energy.« less

First staging of two laser accelerators.

PubMed

Kimura, W D; van Steenbergen, A; Babzien, M; Ben-Zvi, I; Campbell, L P; Cline, D B; Dilley, C E; Gallardo, J C; Gottschalk, S C; He, P; Kusche, K P; Liu, Y; Pantell, R H; Pogorelsky, I V; Quimby, D C; Skaritka, J; Steinhauer, L C; Yakimenko, V

2001-04-30

Staging of two laser-driven, relativistic electron accelerators has been demonstrated for the first time in a proof-of-principle experiment, whereby two distinct and serial laser accelerators acted on an electron beam in a coherently cumulative manner. Output from a CO2 laser was split into two beams to drive two inverse free electron lasers (IFEL) separated by 2.3 m. The first IFEL served to bunch the electrons into approximately 3 fs microbunches, which were rephased with the laser wave in the second IFEL. This represents a crucial step towards the development of practical laser-driven electron accelerators.

Containment of a silicone fluid free surface in reduced gravity using barrier coatings

NASA Technical Reports Server (NTRS)

Pline, Alexander D.; Jacobson, Thomas P.

1988-01-01

In support of the Surface Tension Driven Convection Experiment planned for flight aboard the Space Shuttle, tests were conducted under reduced gravity in the 2.2-sec Drop Tower and the 5.0-sec Zero-G facility at the NASA Lewis Research Center. The dynamics of controlling the test fluid, a 10-cSt viscosity silicone fluid in a low gravity environment were investigated using different container designs and barrier coatings. Three container edge designs were tested without a barrier coating; a square edge, a sharp edge with a 45-deg slope, and a sawtooth edge. All three edge designs were successful in containing the fluid below the edge. G-jitter experiments were made in scaled down containers subjected to horizontal accelerations. The data showed that a barrier coating is effective in containing silicone fluid under g-levels up to 10 sup -1 sub g sub 0. In addition, a second barrier coating was found which has similar anti-wetting characteristics and is also more durable.

Weibel instability mediated collisionless shocks using intense laser-driven plasmas

NASA Astrophysics Data System (ADS)

Palaniyappan, Sasikumar; Fiuza, Federico; Huang, Chengkun; Gautier, Donald; Ma, Wenjun; Schreiber, Jorg; Raymer, Abel; Fernandez, Juan; Shimada, Tom; Johnson, Randall

2017-10-01

The origin of cosmic rays remains a long-standing challenge in astrophysics and continues to fascinate physicists. It is believed that ``collisionless shocks'' - where the particle Coulomb mean free path is much larger that the shock transition - are a dominant source of energetic cosmic rays. These shocks are ubiquitous in astrophysical environments such as gamma-ray bursts, supernova remnants, pulsar wind nebula and coronal mass ejections from the sun. A particular type of electromagnetic plasma instability known as Weibel instability is believed to be the dominant mechanism behind the formation of these collisionless shocks in the cosmos. The understanding of the microphysics behind collisionless shocks and their particle acceleration is tightly related with nonlinear basic plasma processes and remains a grand challenge. In this poster, we will present results from recent experiments at the LANL Trident laser facility studying collisionless shocks using intense ps laser (80J, 650 fs - peak intensity of 1020 W/cm2) driven near-critical plasmas using carbon nanotube foam targets. A second short pulse laser driven protons from few microns thick gold foil is used to radiograph the main laser-driven plasma. Work supported by the LDRD program at LANL.

Downhole fluid injection systems, CO₂ sequestration methods, and hydrocarbon material recovery methods

DOEpatents

Schaef, Herbert T.; McGrail, B. Peter

2015-07-28

Downhole fluid injection systems are provided that can include a first well extending into a geological formation, and a fluid injector assembly located within the well. The fluid injector assembly can be configured to inject a liquid CO₂/H₂O-emulsion into the surrounding geological formation. CO₂ sequestration methods are provided that can include exposing a geological formation to a liquid CO₂/H₂O-emulsion to sequester at least a portion of the CO₂ from the emulsion within the formation. Hydrocarbon material recovery methods are provided that can include exposing a liquid CO₂/H₂O-emulsion to a geological formation having the hydrocarbon material therein. The methods can include recovering at least a portion of the hydrocarbon material from the formation.

Tracking rare-isotope beams with microchannel plates

DOE PAGES

Rogers, A. M.; Sanetullaev, A.; Lynch, W. G.; ...

2015-06-06

A system of two microchannel-plate detectors has been successfully implemented for tracking projectile-fragmentation beams. The detectors provide interaction positions, angles, and arrival Limes of ions at the reaction target. Furthermore, the current design is an adaptation of an assembly used for low-energy beams (~1.4 MeV/nucleon). In order to improve resolution in tracking high-energy heavy-ion beams, the magnetic field strength between the secondary-electron accelerating foil and the microchannel plate had to be increased substantially. Results from an experiment using a 37-MeV/nucleon 56Ni beam show that the tracking system can achieve sub-nanosecond timing resolution and a position resolution of ~1 mm formore » beam intensities up to 5 x 10 5 pps.« less

Tracking rare-isotope beams with microchannel plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogers, A. M.; Sanetullaev, A.; Lynch, W. G.

A system of two microchannel-plate detectors has been successfully implemented for tracking projectile-fragmentation beams. The detectors provide interaction positions, angles, and arrival Limes of ions at the reaction target. Furthermore, the current design is an adaptation of an assembly used for low-energy beams (~1.4 MeV/nucleon). In order to improve resolution in tracking high-energy heavy-ion beams, the magnetic field strength between the secondary-electron accelerating foil and the microchannel plate had to be increased substantially. Results from an experiment using a 37-MeV/nucleon 56Ni beam show that the tracking system can achieve sub-nanosecond timing resolution and a position resolution of ~1 mm formore » beam intensities up to 5 x 10 5 pps.« less

Lunar tidal acceleration obtained from satellite-derived ocean tide parameters

NASA Technical Reports Server (NTRS)

Goad, C. C.; Douglas, B. C.

1978-01-01

One hundred sets of mean elements of GEOS-3 computed at 2-day intervals yielded observation equations for the M sub 2 ocean tide from the long periodic variations of the inclination and node of the orbit. The 2nd degree Love number was given the value k sub 2 = 0.30 and the solid tide phase angle was taken to be zero. Combining obtained equations with results for the satellite 1967-92A gives the M sub 2 ocean tide parameter values. Under the same assumption of zero solid tide phase lag, the lunar tidal acceleration was found mostly due to the C sub 22 term in the expansion of the M sub 2 tide with additional small contributions from the 0 sub 1 and N sub 2 tides. Using Lambeck's (1975) estimates for the latter, the obtained acceleration in lunar longitudal in excellent agreement with the most recent determinations from ancient and modern astronomical data.

Annular MHD Physics for Turbojet Energy Bypass

NASA Technical Reports Server (NTRS)

Schneider, Steven J.

2011-01-01

The use of annular Hall type MHD generator/accelerator ducts for turbojet energy bypass is evaluated assuming weakly ionized flows obtained from pulsed nanosecond discharges. The equations for a 1-D, axisymmetric MHD generator/accelerator are derived and numerically integrated to determine the generator/accelerator performance characteristics. The concept offers a shockless means of interacting with high speed inlet flows and potentially offers variable inlet geometry performance without the complexity of moving parts simply by varying the generator loading parameter. The cycle analysis conducted iteratively with a spike inlet and turbojet flying at M = 7 at 30 km altitude is estimated to have a positive thrust per unit mass flow of 185 N-s/kg. The turbojet allowable combustor temperature is set at an aggressive 2200 deg K. The annular MHD Hall generator/accelerator is L = 3 m in length with a B(sub r) = 5 Tesla magnetic field and a conductivity of sigma = 5 mho/m for the generator and sigma= 1.0 mho/m for the accelerator. The calculated isentropic efficiency for the generator is eta(sub sg) = 84 percent at an enthalpy extraction ratio, eta(sub Ng) = 0.63. The calculated isentropic efficiency for the accelerator is eta(sub sa) = 81 percent at an enthalpy addition ratio, eta(sub Na) = 0.62. An assessment of the ionization fraction necessary to achieve a conductivity of sigma = 1.0 mho/m is n(sub e)/n = 1.90 X 10(exp -6), and for sigma = 5.0 mho/m is n(sub e)/n = 9.52 X 10(exp -6).

Controllability in Multi-Stage Laser Ion Acceleration

NASA Astrophysics Data System (ADS)

Kawata, S.; Kamiyama, D.; Ohtake, Y.; Barada, D.; Ma, Y. Y.; Kong, Q.; Wang, P. X.; Gu, Y. J.; Li, X. F.; Yu, Q.

2015-11-01

The present paper shows a concept for a future laser ion accelerator, which should have an ion source, ion collimators, ion beam bunchers and ion post acceleration devices. Based on the laser ion accelerator components, the ion particle energy and the ion energy spectrum are controlled, and a future compact laser ion accelerator would be designed for ion cancer therapy or for ion material treatment. In this study each component is designed to control the ion beam quality. The energy efficiency from the laser to ions is improved by using a solid target with a fine sub-wavelength structure or a near-critical density gas plasma. The ion beam collimation is performed by holes behind the solid target or a multi-layered solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching are successfully realized by a multi-stage laser-target interaction. A combination of each component provides a high controllability of the ion beam quality to meet variable requirements in various purposes in the laser ion accelerator. The work was partly supported by MEXT, JSPS, ASHULA project/ ILE, Osaka University, CORE (Center for Optical Research and Education, Utsunomiya University, Japan), Fudan University and CDI (Creative Dept. for Innovation) in CCRD, Utsunomiya University.

Assembly and Commissioning of Naval Postgraduate School Gas Gun for Impact Studies

DTIC Science & Technology

2009-12-01

MAIN GAS GUN ASSEMBLY............................................................ 12 1. Launcher Mount Assembly...12 Figure 8. Launcher Mount Assembly [After 5].................................................... 13 Figure 9. Breech...5] The main gas gun assembly comprises of eight sub-assemblies. The assemblies are mounted onto the launcher mount assembly, where it acts as a

Direct Polishing of Full-Shell, High-Resolution X-Ray Optics

NASA Technical Reports Server (NTRS)

Roche, Jacqueline M.; Gubarev, Mikhail V.; Smith, W. Scott; O'Dell, Stephen L.; Kolodziejczak, Jeffrey J.; Weisskopf, Martin C.; Ramsey, Brian D.; Elsner, Ronald F.

2014-01-01

Future x-ray telescopes will likely require lightweight mirrors to attain the large collecting areas needed to accomplish the science objectives. Understanding and demonstrating processes now is critical to achieving sub-arcsecond performance in the future. Consequently, designs not only of the mirrors but of fixtures for supporting them during fabrication, metrology, handling, assembly, and testing must be adequately modeled and verified. To this end, MSFC is using finite-element modeling to study the effects of mounting on thin, full-shell grazing-incidence mirrors, during all processes leading to a flight.

Review of laser-driven ion sources and their applications.

PubMed

Daido, Hiroyuki; Nishiuchi, Mamiko; Pirozhkov, Alexander S

2012-05-01

For many years, laser-driven ion acceleration, mainly proton acceleration, has been proposed and a number of proof-of-principle experiments have been carried out with lasers whose pulse duration was in the nanosecond range. In the 1990s, ion acceleration in a relativistic plasma was demonstrated with ultra-short pulse lasers based on the chirped pulse amplification technique which can provide not only picosecond or femtosecond laser pulse duration, but simultaneously ultra-high peak power of terawatt to petawatt levels. Starting from the year 2000, several groups demonstrated low transverse emittance, tens of MeV proton beams with a conversion efficiency of up to several percent. The laser-accelerated particle beams have a duration of the order of a few picoseconds at the source, an ultra-high peak current and a broad energy spectrum, which make them suitable for many, including several unique, applications. This paper reviews, firstly, the historical background including the early laser-matter interaction studies on energetic ion acceleration relevant to inertial confinement fusion. Secondly, we describe several implemented and proposed mechanisms of proton and/or ion acceleration driven by ultra-short high-intensity lasers. We pay special attention to relatively simple models of several acceleration regimes. The models connect the laser, plasma and proton/ion beam parameters, predicting important features, such as energy spectral shape, optimum conditions and scalings under these conditions for maximum ion energy, conversion efficiency, etc. The models also suggest possible ways to manipulate the proton/ion beams by tailoring the target and irradiation conditions. Thirdly, we review experimental results on proton/ion acceleration, starting with the description of driving lasers. We list experimental results and show general trends of parameter dependences and compare them with the theoretical predictions and simulations. The fourth topic includes a review of scientific, industrial and medical applications of laser-driven proton or ion sources, some of which have already been established, while the others are yet to be demonstrated. In most applications, the laser-driven ion sources are complementary to the conventional accelerators, exhibiting significantly different properties. Finally, we summarize the paper.

Radiatively driven relativistic spherical winds under relativistic radiative transfer

NASA Astrophysics Data System (ADS)

Fukue, J.

2018-05-01

We numerically investigate radiatively driven relativistic spherical winds from the central luminous object with mass M and luminosity L* under Newtonian gravity, special relativity, and relativistic radiative transfer. We solve both the relativistic radiative transfer equation and the relativistic hydrodynamical equations for spherically symmetric flows under the double-iteration processes, to obtain the intensity and velocity fields simultaneously. We found that the momentum-driven winds with scattering are quickly accelerated near the central object to reach the terminal speed. The results of numerical solutions are roughly fitted by a relation of \\dot{m}=0.7(Γ _*-1)\\tau _* β _* β _out^{-2.6}, where \\dot{m} is the mass-loss rate normalized by the critical one, Γ* the central luminosity normalized by the critical one, τ* the typical optical depth, β* the initial flow speed at the central core of radius R*, and βout the terminal speed normalized by the speed of light. This relation is close to the non-relativistic analytical solution, \\dot{m} = 2(Γ _*-1)\\tau _* β _* β _out^{-2}, which can be re-expressed as β _out^2/2 = (Γ _*-1)GM/c^2 R_*. That is, the present solution with small optical depth is similar to that of the radiatively driven free outflow. Furthermore, we found that the normalized luminosity (Eddington parameter) must be larger than unity for the relativistic spherical wind to blow off with intermediate or small optical depth, i.e. Γ _* ≳ \\sqrt{(1+β _out)^3/(1-β _out)}. We briefly investigate and discuss an isothermal wind.

Kinetics of Surface-Driven Self-Assembly and Fatigue-Induced Disassembly of a Virus-Based Nanocoating.

PubMed

Valbuena, Alejandro; Mateu, Mauricio G

2017-02-28

Self-assembling protein layers provide a "bottom-up" approach for precisely organizing functional elements at the nanoscale over a large solid surface area. The design of protein sheets with architecture and physical properties suitable for nanotechnological applications may be greatly facilitated by a thorough understanding of the principles that underlie their self-assembly and disassembly. In a previous study, the hexagonal lattice formed by the capsid protein (CA) of human immunodeficiency virus (HIV) was self-assembled as a monomolecular layer directly onto a solid substrate, and its mechanical properties and dynamics at equilibrium were analyzed by atomic force microscopy. Here, we use atomic force microscopy to analyze the kinetics of self-assembly of the planar CA lattice on a substrate and of its disassembly, either spontaneous or induced by materials fatigue. Both self-assembly and disassembly of the CA layer are cooperative reactions that proceed until a phase equilibrium is reached. Self-assembly requires a critical protein concentration and is initiated by formation of nucleation points on the substrate, followed by lattice growth and eventual merging of CA patches into a continuous monolayer. Disassembly of the CA layer showed hysteresis and appears to proceed only after large enough defects (nucleation points) are formed in the lattice, whose number is largely increased by inducing materials fatigue that depends on mechanical load and its frequency. Implications of the kinetic results obtained for a better understanding of self-assembly and disassembly of the HIV capsid and protein-based two-dimensional nanomaterials and the design of anti-HIV drugs targeting (dis)assembly and biocompatible nanocoatings are discussed. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Thermal Fatigue Evaluation of Pb-Free Solder Joints: Results, Lessons Learned, and Future Trends

NASA Astrophysics Data System (ADS)

Coyle, Richard J.; Sweatman, Keith; Arfaei, Babak

2015-09-01

Thermal fatigue is a major source of failure of solder joints in surface mount electronic components and it is critically important in high reliability applications such as telecommunication, military, and aeronautics. The electronic packaging industry has seen an increase in the number of Pb-free solder alloy choices beyond the common near-eutectic Sn-Ag-Cu alloys first established as replacements for eutectic SnPb. This paper discusses the results from Pb-free solder joint reliability programs sponsored by two industry consortia. The characteristic life in accelerated thermal cycling is reported for 12 different Pb-free solder alloys and a SnPb control in 9 different accelerated thermal cycling test profiles in terms of the effects of component type, accelerated thermal cycling profile and dwell time. Microstructural analysis on assembled and failed samples was performed to investigate the effect of initial microstructure and its evolution during accelerated thermal cycling test. A significant finding from the study is that the beneficial effect of Ag on accelerated thermal cycling reliability (measured by characteristic lifetime) diminishes as the severity of the accelerated thermal cycling, defined by greater ΔT, higher peak temperature, and longer dwell time increases. The results also indicate that all the Pb-free solders are more reliable in accelerated thermal cycling than the SnPb alloy they have replaced. Suggestions are made for future work, particularly with respect to the continued evolution of alloy development for emerging application requirements and the value of using advanced analytical methods to provide a better understanding of the effect of microstructure and its evolution on accelerated thermal cycling performance.

Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness

NASA Astrophysics Data System (ADS)

Labate, Luca; Andreassi, Maria Grazia; Baffigi, Federica; Basta, Giuseppina; Bizzarri, Ranieri; Borghini, Andrea; Candiano, Giuliana C.; Casarino, Carlo; Cresci, Monica; Di Martino, Fabio; Fulgentini, Lorenzo; Ghetti, Francesco; Gilardi, Maria Carla; Giulietti, Antonio; Köster, Petra; Lenci, Francesco; Levato, Tadzio; Oishi, Yuji; Russo, Giorgio; Sgarbossa, Antonella; Traino, Claudio; Gizzi, Leonida A.

2013-05-01

Laser-driven electron accelerators based on the Laser Wakefield Acceleration process has entered a mature phase to be considered as alternative devices to conventional radiofrequency linear accelerators used in medical applications. Before entering the medical practice, however, deep studies of the radiobiological effects of such short bunches as the ones produced by laser-driven accelerators have to be performed. Here we report on the setup, characterization and first test of a small-scale laser accelerator for radiobiology experiments. A brief description of the experimental setup will be given at first, followed by an overview of the electron bunch characterization, in particular in terms of dose delivered to the samples. Finally, the first results from the irradiation of biological samples will be briefly discussed.

Plasmon-driven acceleration in a photo-excited nanotube

DOE PAGES

Shin, Young -Min

2017-02-21

A plasmon-assisted channeling acceleration can be realized with a large channel, possibly at the nanometer scale. Carbon nanotubes (CNTs) are the most typical example of nano-channels that can confine a large number of channeled particles in a photon-plasmon coupling condition. This paper presents a theoretical and numerical study on the concept of high-field charge acceleration driven by photo-excited Luttinger-liquid plasmons in a nanotube. An analytic description of the plasmon-assisted laser acceleration is detailed with practical acceleration parameters, in particular, with the specifications of a typical tabletop femtosecond laser system. Lastly, the maximally achievable acceleration gradients and energy gains within dephasingmore » lengths and CNT lengths are discussed with respect to laser-incident angles and CNT-filling ratios.« less

Laser-driven acceleration of electrons in a partially ionized plasma channel.

PubMed

Rowlands-Rees, T P; Kamperidis, C; Kneip, S; Gonsalves, A J; Mangles, S P D; Gallacher, J G; Brunetti, E; Ibbotson, T; Murphy, C D; Foster, P S; Streeter, M J V; Budde, F; Norreys, P A; Jaroszynski, D A; Krushelnick, K; Najmudin, Z; Hooker, S M

2008-03-14

The generation of quasimonoenergetic electron beams, with energies up to 200 MeV, by a laser-plasma accelerator driven in a hydrogen-filled capillary discharge waveguide is investigated. Injection and acceleration of electrons is found to depend sensitively on the delay between the onset of the discharge current and the arrival of the laser pulse. A comparison of spectroscopic and interferometric measurements suggests that injection is assisted by laser ionization of atoms or ions within the channel.

Relativistic klystron driven compact high gradient accelerator as an injector to an X-ray synchrotron radiation ring

DOEpatents

Yu, David U. L.

1990-01-01

A compact high gradient accelerator driven by a relativistic klystron is utilized to inject high energy electrons into an X-ray synchrotron radiation ring. The high gradients provided by the relativistic klystron enables accelerator structure to be much shorter (typically 3 meters) than conventional injectors. This in turn enables manufacturers which utilize high energy, high intensity X-rays to produce various devices, such as computer chips, to do so on a cost effective basis.

Arc-driven rail accelerator research

NASA Technical Reports Server (NTRS)

Ray, Pradosh K.

1987-01-01

Arc-driven rail accelerator research is analyzed by considering wall ablation and viscous drag in the plasma. Plasma characteristics are evaluated through a simple fluid-mechanical analysis considering only wall ablation. By equating the energy dissipated in the plasma with the radiation heat loss, the average properties of the plasma are determined as a function of time and rate of ablation. Locations of two simultaneously accelerating arcs were determined by optical and magnetic probes and fron streak camera photographs. All three measurements provide consistent results.

Lag periods during the self-assembly of {Mo(72)Fe(30)} macroions: connection to the virus capsid formation process.

PubMed

Zhang, Jie; Li, Dong; Liu, Guang; Glover, Kerney Jebrell; Liu, Tianbo

2009-10-28

The kinetic properties of the self-assembly of hydrophilic Keplerate-type polyoxometalate (POM) {Mo(72)Fe(30)} macroanions into single-layer, vesicle-like blackberry structures in solutions were monitored by the static and dynamic laser light scattering techniques. In the presence of additional electrolytes, an obvious lag period at the initial stage of self-assembly was observed, followed by a fast increase of the scattered intensity. The whole kinetic curve is sigmoidal with a lag phase. A two-step nucleation-growth mechanism is proposed to explain this lag phase: the {Mo(72)Fe(30)} macroanions slowly associate into oligomers (mostly dimers), which are the thermodynamically unfavorable intermediates, at the initial stage; once the oligomers reach a critical concentration, the blackberry formation process is accelerated. Analytical ultracentrifugation (AUC) was used to confirm the oligomeric state in {Mo(72)Fe(30)} solution during the lag period. The length of the lag period is dependent on temperature, ionic strength, and the valent states of the additional salts, as well as the solvent content. The kinetics (including the lag period) of the blackberry formation of the {Mo(72)Fe(30)} macroanions show similarities to the self-assembly of virus capsid proteins (which are also soluble macroions) into spherical capsid shells, suggesting possible connections between the self-assembly behaviors of inorganic species and biological macromolecules.

Y{sub 2}O{sub 3}:Yb/Er nanotubes: Layer-by-layer assembly on carbon-nanotube templates and their upconversion luminescence properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Weishi; Shen, Jianfeng; Wan, Lei

2012-11-15

Graphical abstract: Well-shaped Y{sub 2}O{sub 3}:Yb/Er nanotubes have been successfully synthesized on a large scale via layer-by-layer assembly on carbon nanotubes templates followed by a subsequent heat treatment process. The as-prepared Y{sub 2}O{sub 3}:Yb/Er nanotubes show a strong red emission corresponding to the {sup 4}F{sub 9/2}–{sup 4}I{sub 15/2} transition of the Er{sup 3+} ions under excitation at 980 nm. Display Omitted Highlights: ► Well-shaped Y{sub 2}O{sub 3}:Yb/Er nanotubes have been successfully synthesized. ► CNTs were used as templates for Y{sub 2}O{sub 3}:Yb/Er nanotubes. ► LBL assembly and calcination were used for preparation of Y{sub 2}O{sub 3}:Yb/Er nanotubes. ► The as-preparedmore » Y{sub 2}O{sub 3}:Yb/Er nanotubes show a strong red emission. -- Abstract: Well-shaped Y{sub 2}O{sub 3}:Yb/Er nanotubes have been successfully synthesized on a large scale via layer-by-layer (LBL) assembly on carbon nanotubes (CNTs) templates followed by a subsequent heat treatment process. The crystal structure, element analysis, morphology and upconversion luminescence properties were characterized. XRD results demonstrate that the diffraction peaks of the samples calcinated at 800 °C or above can be indexed to the pure cubic phase of Y{sub 2}O{sub 3}. SEM images indicate that a large quantity of uniform and rough nanotubes with diameters of about 30–60 nm can be observed. The as-prepared Y{sub 2}O{sub 3}:Yb/Er nanotubes show a strong red emission corresponding to the {sup 4}F{sub 9/2}–{sup 4}I{sub 15/2} transition of the Er{sup 3+} ions under excitation at 980 nm, which have potential applications in such fields as nanoscale devices, molecular catalysts, nanobiotechnology, photonics and optoelectronics.« less

Modeling Particle Acceleration and Transport at a 2-D CME-Driven Shock

NASA Astrophysics Data System (ADS)

Hu, Junxiang; Li, Gang; Ao, Xianzhi; Zank, Gary P.; Verkhoglyadova, Olga

2017-11-01

We extend our earlier Particle Acceleration and Transport in the Heliosphere (PATH) model to study particle acceleration and transport at a coronal mass ejection (CME)-driven shock. We model the propagation of a CME-driven shock in the ecliptic plane using the ZEUS-3D code from 20 solar radii to 2 AU. As in the previous PATH model, the initiation of the CME-driven shock is simplified and modeled as a disturbance at the inner boundary. Different from the earlier PATH model, the disturbance is now longitudinally dependent. Particles are accelerated at the 2-D shock via the diffusive shock acceleration mechanism. The acceleration depends on both the parallel and perpendicular diffusion coefficients κ|| and κ⊥ and is therefore shock-obliquity dependent. Following the procedure used in Li, Shalchi, et al. (k href="#jgra53857-bib-0045"/>), we obtain the particle injection energy, the maximum energy, and the accelerated particle spectra at the shock front. Once accelerated, particles diffuse and convect in the shock complex. The diffusion and convection of these particles are treated using a refined 2-D shell model in an approach similar to Zank et al. (k href="#jgra53857-bib-0089"/>). When particles escape from the shock, they propagate along and across the interplanetary magnetic field. The propagation is modeled using a focused transport equation with the addition of perpendicular diffusion. We solve the transport equation using a backward stochastic differential equation method where adiabatic cooling, focusing, pitch angle scattering, and cross-field diffusion effects are all included. Time intensity profiles and instantaneous particle spectra as well as particle pitch angle distributions are shown for two example CME shocks.

Laser acceleration of quasi-monoenergetic MeV ion beams.

PubMed

Hegelich, B M; Albright, B J; Cobble, J; Flippo, K; Letzring, S; Paffett, M; Ruhl, H; Schreiber, J; Schulze, R K; Fernández, J C

2006-01-26

Acceleration of particles by intense laser-plasma interactions represents a rapidly evolving field of interest, as highlighted by the recent demonstration of laser-driven relativistic beams of monoenergetic electrons. Ultrahigh-intensity lasers can produce accelerating fields of 10 TV m(-1) (1 TV = 10(12) V), surpassing those in conventional accelerators by six orders of magnitude. Laser-driven ions with energies of several MeV per nucleon have also been produced. Such ion beams exhibit unprecedented characteristics--short pulse lengths, high currents and low transverse emittance--but their exponential energy spectra have almost 100% energy spread. This large energy spread, which is a consequence of the experimental conditions used to date, remains the biggest impediment to the wider use of this technology. Here we report the production of quasi-monoenergetic laser-driven C5+ ions with a vastly reduced energy spread of 17%. The ions have a mean energy of 3 MeV per nucleon (full-width at half-maximum approximately 0.5 MeV per nucleon) and a longitudinal emittance of less than 2 x 10(-6) eV s for pulse durations shorter than 1 ps. Such laser-driven, high-current, quasi-monoenergetic ion sources may enable significant advances in the development of compact MeV ion accelerators, new diagnostics, medical physics, inertial confinement fusion and fast ignition.

Replacing ODCs in a Critical Hand Cleaning Manual Electronics Assembly Operation

NASA Technical Reports Server (NTRS)

Bonner, J. K.; Walton, Sharon

1997-01-01

The manufacture of high reliability electronics assemblies for spacecraft and ground support equipment still often involves manual assembly processes. In addition, rework and repair of critical assemblies aslo often entails manual assembly processes.

Hierarchically macro–mesoporous TiO{sub 2} film via self-assembled strategy for enhanced efficiency of dye sensitized solar cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Ping; Wang, Jin; Yu, Huogen, E-mail: yuhuogen@whut.edu.cn

2016-02-15

Highlights: • A new hierarchically macro–mesoporous TiO{sub 2} film is fabricated via TiF{sub 4} hydrolysis. • TiF{sub 4} hydrolysis is accompanied with self-assembled process of TiO{sub 2} nanoparticles. • The hierarchically porous TiO{sub 2} films show higher performance than nonporous film. - Abstract: The hierarchically porous structure of TiO{sub 2} film plays an important role on improved photoelectric conversion efficiency in dye-sensitized solar cells (DSSCs). It is highly required to develop a facile strategy to prepare the hierarchical porous photoelectrode. In this study, a novel hierarchically macro–mesoporous TiO{sub 2} film as photoelectrode of DSSCs is fabricated by a self-assembled processmore » of TiO{sub 2} nanoparticles via TiF{sub 4} hydrolysis. The hydrolysis of TiF{sub 4} is accompanied with self-assembled process of TiO{sub 2} nanoparticles on the surface of electrophoretic-deposited titanate nanotube film which provides effective active sites for the deposition of TiO{sub 2} nanoparticles owing to a large amount of hydroxyl groups, resulting in the formation of hierarchically porous structures. The hierarchically porous TiO{sub 2} film is mainly composed of mesopores with a size of 2–50 nm and macropores with a wide range of 0.5–5 μm, which contribute to an obviously higher conversion performance (6.70%) than nonporous P25-TiO{sub 2} film (4.01%). The main reasons for enhanced conversion efficiency of hierarchically porous TiO{sub 2} film can be attributed to adsorption of more dye molecules, rapid diffusion and efficient transport of electrolyte, and longer electron lifetime. This work may provide new insights into preparing porous structure of TiO{sub 2} films in DSSCs for modification of photoelectric conversion efficiency.« less

Effects of laser polarization on electrostatic shock ion acceleration in near-critical plasmas

NASA Astrophysics Data System (ADS)

Kim, Young-Kuk; Kang, Teyoun; Hur, Min Sup

2016-10-01

Collisionless electrostatic shock ion acceleration has become a major regime of laser-driven ion acceleration owing to generation of quasi-monoenergetic ion beams from moderate parametric conditions of lasers and plasmas in comparison with target-normal-sheath-acceleration or radiation pressure acceleration. In order to construct the shock, plasma heating is an essential condition for satisfying Mach number condition 1.5

Methods for batch fabrication of cold cathode vacuum switch tubes

DOEpatents

Walker, Charles A [Albuquerque, NM; Trowbridge, Frank R [Albuquerque, NM

2011-05-10

Methods are disclosed for batch fabrication of vacuum switch tubes that reduce manufacturing costs and improve tube to tube uniformity. The disclosed methods comprise creating a stacked assembly of layers containing a plurality of adjacently spaced switch tube sub-assemblies aligned and registered through common layers. The layers include trigger electrode layer, cathode layer including a metallic support/contact with graphite cathode inserts, trigger probe sub-assembly layer, ceramic (e.g. tube body) insulator layer, and metallic anode sub-assembly layer. Braze alloy layers are incorporated into the stacked assembly of layers, and can include active metal braze alloys or direct braze alloys, to eliminate costs associated with traditional metallization of the ceramic insulator layers. The entire stacked assembly is then heated to braze/join/bond the stack-up into a cohesive body, after which individual switch tubes are singulated by methods such as sawing. The inventive methods provide for simultaneously fabricating a plurality of devices as opposed to traditional methods that rely on skilled craftsman to essentially hand build individual devices.

Supramolecular guests in solvent driven block copolymer assembly: From internally structured nanoparticles to micelles

PubMed Central

Klinger, Daniel; Robb, Maxwell J.; Spruell, Jason M.; Lynd, Nathaniel A.; Hawker, Craig J.

2014-01-01

Supramolecular interactions between different hydrogen-bonding guests and poly(2-vinyl pyridine)-block-poly (styrene) can be exploited to prepare remarkably diverse self-assembled nanostructures in dispersion from a single block copolymer (BCP). The characteristics of the BCP can be efficiently controlled by tailoring the properties of a guest which preferentially binds to the P2VP block. For example, the incorporation of a hydrophobic guest creates a hydrophobic BCP complex that forms phase separated nanoparticles upon self-assembly. Conversely, the incorporation of a hydrophilic guest results in an amphiphilic BCP complex that forms spherical micelles in water. The ability to tune the self-assembly behavior and access dramatically different nanostructures from a single BCP substrate demonstrates the exceptional versatility of the self-assembly of BCPs driven by supramolecular interactions. This approach represents a new methodology that will enable the further design of complex, responsive self-assembled nanostructures. PMID:25525473

Counteranion Driven Homochiral Assembly of a Cationic C3-Symmetric Gelator through Ion-Pair Assisted Hydrogen Bond.

PubMed

Maity, Arunava; Gangopadhyay, Monalisa; Basu, Arghya; Aute, Sunil; Babu, Sukumaran Santhosh; Das, Amitava

2016-09-07

The helical handedness in achiral self-assemblies is mostly complex due to spontaneous symmetry breaking or kinetically controlled random assembly formation. Here an attempt has been made to address this issue through chiral anion exchange. A new class of cationic achiral C3-symmetric gelator devoid of any conventional gelation assisting functional units is found to form both right- and left-handed helical structures. A chiral counteranion exchange-assisted approach is successfully introduced to control the chirality sign and thereby to obtain preferred homochiral assemblies. Formation of anion-assisted chiral assembly was confirmed by circular dichroism (CD) spectroscopy, microscopic images, and crystal structure. The X-ray crystal structure reveals the construction of helical assemblies with opposite handedness for (+)- and (-)-chiral anion reformed gelators. The appropriate counteranion driven ion-pair-assisted hydrogen-bonding interactions are found responsible for the helical bias control in this C3-symmetric gelator.

A statistical study of current-sheet formation above solar active regions based on selforganized criticality

NASA Astrophysics Data System (ADS)

Dimitropoulou, M.; Isliker, H.; Vlahos, L.; Georgoulis, M.; Anastasiadis, A.; Toutountzi, A.

2013-09-01

We treat flaring solar active regions as physical systems having reached the self-organized critical state. Their evolving magnetic configurations in the low corona may satisfy an instability criterion, related to the excession of a specific threshold in the curl of the magnetic field. This imposed instability criterion implies an almost zero resistivity everywhere in the solar corona, except in regions where magnetic-field discontinuities and. hence, local currents, reach the critical value. In these areas, current-driven instabilities enhance the resistivity by many orders of magnitude forming structures which efficiently accelerate charged particles. Simulating the formation of such structures (thought of as current sheets) via a refined SOC cellular-automaton model provides interesting information regarding their statistical properties. It is shown that the current density in such unstable regions follows power-law scaling. Furthermore, the size distribution of the produced current sheets is best fitted by power laws, whereas their formation probability is investigated against the photospheric magnetic configuration (e.g. Polarity Inversion Lines, Plage). The average fractal dimension of the produced current sheets is deduced depending on the selected critical threshold. The above-mentioned statistical description of intermittent electric field structures can be used by collisional relativistic test particle simulations, aiming to interpret particle acceleration in flaring active regions and in strongly turbulent media in astrophysical plasmas. The above work is supported by the Hellenic National Space Weather Research Network (HNSWRN) via the THALIS Programme.

Critical Nucleation Length for Accelerating Frictional Slip

NASA Astrophysics Data System (ADS)

Aldam, Michael; Weikamp, Marc; Spatschek, Robert; Brener, Efim A.; Bouchbinder, Eran

2017-11-01

The spontaneous nucleation of accelerating slip along slowly driven frictional interfaces is central to a broad range of geophysical, physical, and engineering systems, with particularly far-reaching implications for earthquake physics. A common approach to this problem associates nucleation with an instability of an expanding creep patch upon surpassing a critical length Lc. The critical nucleation length Lc is conventionally obtained from a spring-block linear stability analysis extended to interfaces separating elastically deformable bodies using model-dependent fracture mechanics estimates. We propose an alternative approach in which the critical nucleation length is obtained from a related linear stability analysis of homogeneous sliding along interfaces separating elastically deformable bodies. For elastically identical half-spaces and rate-and-state friction, the two approaches are shown to yield Lc that features the same scaling structure, but with substantially different numerical prefactors, resulting in a significantly larger Lc in our approach. The proposed approach is also shown to be naturally applicable to finite-size systems and bimaterial interfaces, for which various analytic results are derived. To quantitatively test the proposed approach, we performed inertial Finite-Element-Method calculations for a finite-size two-dimensional elastically deformable body in rate-and-state frictional contact with a rigid body under sideway loading. We show that the theoretically predicted Lc and its finite-size dependence are in reasonably good quantitative agreement with the full numerical solutions, lending support to the proposed approach. These results offer a theoretical framework for predicting rapid slip nucleation along frictional interfaces.

Electric field directed assembly of high-density microbead arrays†

PubMed Central

Barbee, Kristopher D.; Hsiao, Alexander P.; Heller, Michael J.; Huang, Xiaohua

2010-01-01

We report a method for rapid, electric field directed assembly of high-density protein-conjugated microbead arrays. Photolithography is used to fabricate an array of micron to sub-micron-scale wells in an epoxy-based photoresist on a silicon wafer coated with a thin gold film, which serves as the primary electrode. A thin gasket is used to form a microfluidic chamber between the wafer and a glass coverslip coated with indium-tin oxide, which serves as the counter electrode. Streptavidin-conjugated microbeads suspended in a low conductance buffer are introduced into the chamber and directed into the wells via electrophoresis by applying a series of low voltage electrical pulses across the electrodes. Hundreds of millions of microbeads can be permanently assembled on these arrays in as little as 30 seconds and the process can be monitored in real time using epifluorescence microscopy. The binding of the microbeads to the gold film is robust and occurs through electrochemically induced gold-protein interactions, which allows excess beads to be washed away or recycled. The well and bead sizes are chosen such that only one bead can be captured in each well. Filling efficiencies greater than 99.9% have been demonstrated across wafer-scale arrays with densities as high as 69 million beads per cm2. Potential applications for this technology include the assembly of DNA arrays for high-throughput genome sequencing and antibody arrays for proteomic studies. Following array assembly, this device may also be used to enhance the concentration-dependent processes of various assays through the accelerated transport of molecules using electric fields. PMID:19865735

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Terry Alan; Hogan, Roy E., Jr.; McDaniel, Anthony H.

Two of the most daunting problems facing humankind in the twenty-first century are energy security and climate change. This report summarizes work accomplished towards addressing these problems through the execution of a Grand Challenge LDRD project (FY09-11). The vision of Sunshine to Petrol is captured in one deceptively simple chemical equation: Solar Energy + xCO{sub 2} + (x+1)H{sub 2}O {yields} C{sub x}H{sub 2x+2}(liquid fuel) + (1.5x+.5)O{sub 2} Practical implementation of this equation may seem far-fetched, since it effectively describes the use of solar energy to reverse combustion. However, it is also representative of the photosynthetic processes responsible for much ofmore » life on earth and, as such, summarizes the biomass approach to fuels production. It is our contention that an alternative approach, one that is not limited by efficiency of photosynthesis and more directly leads to a liquid fuel, is desirable. The development of a process that efficiently, cost effectively, and sustainably reenergizes thermodynamically spent feedstocks to create reactive fuel intermediates would be an unparalleled achievement and is the key challenge that must be surmounted to solve the intertwined problems of accelerating energy demand and climate change. We proposed that the direct thermochemical conversion of CO{sub 2} and H{sub 2}O to CO and H{sub 2}, which are the universal building blocks for synthetic fuels, serve as the basis for this revolutionary process. To realize this concept, we addressed complex chemical, materials science, and engineering problems associated with thermochemical heat engines and the crucial metal-oxide working-materials deployed therein. By project's end, we had demonstrated solar-driven conversion of CO{sub 2} to CO, a key energetic synthetic fuel intermediate, at 1.7% efficiency.« less

Excellent performances of energy harvester using cantilever driving double-clamped 0.7Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-0.3PbTiO{sub 3} plates and symmetric middle-stops

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeng, Zhou; Xu, Qing; University of Chinese Academy of Sciences, Beijing 100049

We present a high performance nonlinear piezoelectric energy harvester constituted by a cantilever with symmetrically middle-stops and double-clamped piezoelectric plates based on piezoelectric single crystal 0.7Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-0.3PbTiO{sub 3}. Electrical properties of the device under different excitation frequencies, accelerations, and load resistances are studied systematically. Under a low acceleration of 3 m/s{sup 2} (0.3 g), a peak voltage of 26.2 V and a maximum normalized power of 25.6 mW/g{sup 2} were obtained across a matching impedance of 600 kΩ with favorable bandwidths. The low excitation acceleration and excellent performances indicate that the device can be a promising candidate for energy harvesting in low-power electronicsmore » and wireless sensors.« less

Quantum paraelectricity in copper-titanates: Magnetic-order driven vitrification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, Jitender; Awasthi, A. M., E-mail: amawasthi@csr.res.in

2015-07-21

Quantum-paraelectric (QP) family character is emergent from shared low-temperature characteristics of SrCu{sub 3}Ti{sub 4}O{sub 12} (SCTO), CaCu{sub 3}Ti{sub 4}O{sub 12} (CCTO), and Ca{sub 0.9}Li{sub 0.1}Cu{sub 3}Ti{sub 4}O{sub 12} (CLCTO) A{sub 1/4}A′{sub 3/4}BO{sub 3} structures featuring antiferro-tilted Ti-O{sub 6} octahedra. Above their magnetic ordering temperatures T{sub N}, permittivity of SCTO and CLCTO follow typical Barrett form, whereas in CCTO, quantum paraelectricity is masked by the huge ε′-step. Hidden QP in CCTO gets revealed by Li-doping at the Ca-site, which considerably up-shifts the temperature scale (from ∼100 K to ∼250 K) of the dielectric step-anomaly in CLCTO. Competing magneto-electricity and quantum fluctuations result inmore » glassy-arrest of the QP degrees of freedom near T{sub N}; manifest as dispersive-deviation of the permittivity (in SCTO and CLCTO) from the low-temperature Barrett saturation. However, quantum criticality (QC) regime being well above T{sub N} registers its presence nevertheless, as the ∼T{sup 2} behaviour of their inverse dielectric susceptibility. Non-compliance to the usual behaviours of dispersive-response vs. bias-field and temperature unambiguously rule out a relaxor origin of the glassy state. We determine a dimensionless thermal window (0.3 ≤ T/T{sub 1} ≤ 0.6) of QC signature, covering typical quantum-paraelectrics.« less

Laser Wakefield Acceleration: Structural and Dynamic Studies. Final Technical Report ER40954

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downer, Michael C.

2014-04-30

Particle accelerators enable scientists to study the fundamental structure of the universe, but have become the largest and most expensive of scientific instruments. In this project, we advanced the science and technology of laser-plasma accelerators, which are thousands of times smaller and less expensive than their conventional counterparts. In a laser-plasma accelerator, a powerful laser pulse exerts light pressure on an ionized gas, or plasma, thereby driving an electron density wave, which resembles the wake behind a boat. Electrostatic fields within this plasma wake reach tens of billions of volts per meter, fields far stronger than ordinary non-plasma matter (suchmore » as the matter that a conventional accelerator is made of) can withstand. Under the right conditions, stray electrons from the surrounding plasma become trapped within these “wake-fields”, surf them, and acquire energy much faster than is possible in a conventional accelerator. Laser-plasma accelerators thus might herald a new generation of compact, low-cost accelerators for future particle physics, x-ray and medical research. In this project, we made two major advances in the science of laser-plasma accelerators. The first of these was to accelerate electrons beyond 1 gigaelectronvolt (1 GeV) for the first time. In experimental results reported in Nature Communications in 2013, about 1 billion electrons were captured from a tenuous plasma (about 1/100 of atmosphere density) and accelerated to 2 GeV within about one inch, while maintaining less than 5% energy spread, and spreading out less than ½ milliradian (i.e. ½ millimeter per meter of travel). Low energy spread and high beam collimation are important for applications of accelerators as coherent x-ray sources or particle colliders. This advance was made possible by exploiting unique properties of the Texas Petawatt Laser, a powerful laser at the University of Texas at Austin that produces pulses of 150 femtoseconds (1 femtosecond is 10-15 seconds) in duration and 150 Joules in energy (equivalent to the muzzle energy of a small pistol bullet). This duration was well matched to the natural electron density oscillation period of plasma of 1/100 atmospheric density, enabling efficient excitation of a plasma wake, while this energy was sufficient to drive a high-amplitude wake of the right shape to produce an energetic, collimated electron beam. Continuing research is aimed at increasing electron energy even further, increasing the number of electrons captured and accelerated, and developing applications of the compact, multi-GeV accelerator as a coherent, hard x-ray source for materials science, biomedical imaging and homeland security applications. The second major advance under this project was to develop new methods of visualizing the laser-driven plasma wake structures that underlie laser-plasma accelerators. Visualizing these structures is essential to understanding, optimizing and scaling laser-plasma accelerators. Yet prior to work under this project, computer simulations based on estimated initial conditions were the sole source of detailed knowledge of the complex, evolving internal structure of laser-driven plasma wakes. In this project we developed and demonstrated a suite of optical visualization methods based on well-known methods such as holography, streak cameras, and coherence tomography, but adapted to the ultrafast, light-speed, microscopic world of laser-driven plasma wakes. Our methods output images of laser-driven plasma structures in a single laser shot. We first reported snapshots of low-amplitude laser wakes in Nature Physics in 2006. We subsequently reported images of high-amplitude laser-driven plasma “bubbles”, which are important for producing electron beams with low energy spread, in Physical Review Letters in 2010. More recently, we have figured out how to image laser-driven structures that change shape while propagating in a single laser shot. The latter techniques, which use the methods of computerized tomography, were demonstrated on test objects – e.g. laser-driven filaments in air and glass – and reported in Optics Letters in 2013 and Nature Communications in 2014. Their output is a multi-frame movie rather than a snapshot. Continuing research is aimed at applying these tomographic methods directly to evolving laser-driven plasma accelerator structures in our laboratory, then, once perfected, to exporting them to plasma-based accelerator laboratories around the world as standard in-line metrology instruments.« less

Development of simulation approach for two-dimensional chiral molecular self-assembly driven by hydrogen bond at the liquid/solid interface

NASA Astrophysics Data System (ADS)

Qin, Yuan; Yao, Man; Hao, Ce; Wan, Lijun; Wang, Yunhe; Chen, Ting; Wang, Dong; Wang, Xudong; Chen, Yonggang

2017-09-01

Two-dimensional (2D) chiral self-assembly system of 5-(benzyloxy)-isophthalic acid derivative/(S)-(+)-2-octanol/highly oriented pyrolytic graphite was studied. A combined density functional theory/molecular mechanics/molecular dynamics (DFT/MM/MD) approach for system of 2D chiral molecular self-assembly driven by hydrogen bond at the liquid/solid interface was thus proposed. Structural models of the chiral assembly were built on the basis of scanning tunneling microscopy (STM) images and simplified for DFT geometry optimization. Merck Molecular Force Field (MMFF) was singled out as the suitable force field by comparing the optimized configurations of MM and DFT. MM and MD simulations for hexagonal unit model which better represented the 2D assemble network were then preformed with MMFF. The adhesion energy, evolution of self-assembly process and characteristic parameters of hydrogen bond were obtained and analyzed. According to the above simulation, the stabilities of the clockwise and counterclockwise enantiomorphous networks were evaluated. The calculational results were supported by STM observations and the feasibility of the simulation method was confirmed by two other systems in the presence of chiral co-absorbers (R)-(-)-2-octanol and achiral co-absorbers 1-octanol. This theoretical simulation method assesses the stability trend of 2D enantiomorphous assemblies with atomic scale and can be applied to the similar hydrogen bond driven 2D chirality of molecular self-assembly system.

ON THE IMPACT OF THREE DIMENSIONS IN SIMULATIONS OF NEUTRINO-DRIVEN CORE-COLLAPSE SUPERNOVA EXPLOSIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Couch, Sean M., E-mail: smc@flash.uchicago.edu

2013-09-20

We present one-dimensional (1D), two-dimensional (2D), and three-dimensional (3D) hydrodynamical simulations of core-collapse supernovae including a parameterized neutrino heating and cooling scheme in order to investigate the critical core neutrino luminosity (L{sub crit}) required for explosion. In contrast to some previous works, we find that 3D simulations explode later than 2D simulations, and that L{sub crit} at fixed mass accretion rate is somewhat higher in three dimensions than in two dimensions. We find, however, that in two dimensions L{sub crit} increases as the numerical resolution of the simulation increases. In contrast to some previous works, we argue that the averagemore » entropy of the gain region is in fact not a good indicator of explosion but is rather a reflection of the greater mass in the gain region in two dimensions. We compare our simulations to semi-analytic explosion criteria and examine the nature of the convective motions in two dimensions and three dimensions. We discuss the balance between neutrino-driven buoyancy and drag forces. In particular, we show that the drag force will be proportional to a buoyant plume's surface area while the buoyant force is proportional to a plume's volume and, therefore, plumes with greater volume-to-surface-area ratios will rise more quickly. We show that buoyant plumes in two dimensions are inherently larger, with greater volume-to-surface-area ratios, than plumes in three dimensions. In the scenario that the supernova shock expansion is dominated by neutrino-driven buoyancy, this balance between buoyancy and drag forces may explain why 3D simulations explode later than 2D simulations and why L{sub crit} increases with resolution. Finally, we provide a comparison of our results with other calculations in the literature.« less

Hybridized Kibble-Zurek scaling in the driven critical dynamics across an overlapping critical region

NASA Astrophysics Data System (ADS)

Zhai, Liang-Jun; Wang, Huai-Yu; Yin, Shuai

2018-04-01

The conventional Kibble-Zurek scaling describes the scaling behavior in the driven dynamics across a single critical region. In this paper, we study the driven dynamics across an overlapping critical region, in which a critical region (Region A) is overlaid by another critical region (Region B). We develop a hybridized Kibble-Zurek scaling (HKZS) to characterize the scaling behavior in the driven process. According to the HKZS, the driven dynamics in the overlapping region can be described by the critical theories for both Region A and Region B simultaneously. This results in a constraint on the scaling function in the overlapping critical region. We take the quantum Ising chain in an imaginary longitudinal field as an example. In this model, the critical region of the Yang-Lee edge singularity and the critical region of the ferromagnetic-paramagnetic phase transition overlap with each other. We numerically confirm the HKZS by simulating the driven dynamics in this overlapping critical region. The HKZSs in other models are also discussed.

Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

NASA Astrophysics Data System (ADS)

Boella, E.; Fiúza, F.; Stockem Novo, A.; Fonseca, R.; Silva, L. O.

2018-03-01

A numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ions by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.

Optimization of Capsule Symmetry in Z-Pinch Driven Hohlraums

NASA Astrophysics Data System (ADS)

Vesey, R. A.; Cuneo, M.; Hanson, D.; Porter, J.; Mehlhorn, T.; Ruggles, L.; Simpson, W.; Vargas, M.; Hammer, J.; Landen, O.

1999-11-01

The uniformity of the radiation flux incident on the capsule is a critical issue for indirect drive fusion using the z-pinch driven hohlraum high-yield concept(J.H. Hammer et al., Phys. Plas. 6), 2129 (1999).. Experiments on the Z accelerator at Sandia have demonstrated the ability to diagnose the uniformity of the flux striking a foam ball (surrogate capsule)(P.A. Amendt et al., Phys. Plas. 4), 1862 (1997); S.G. Glendinning et al. Rev. Sci. Instrum. 70, 536 (1999).. These single-sided drive experiments have been modeled using radiosity and radiation-hydrodynamics codes, yielding agreement with the measured ablation rate vs. angle on the foam ball. Flux uniformity at the 1-2% level needed for high-convergence capsule implosions requires a 2-sided drive (top and bottom z-pinch) configuration. Constrained optimization methods have identified hohlraum geometries with improved symmetry.

Materials Knowledge Systems in Python - A Data Science Framework for Accelerated Development of Hierarchical Materials.

PubMed

Brough, David B; Wheeler, Daniel; Kalidindi, Surya R

2017-03-01

There is a critical need for customized analytics that take into account the stochastic nature of the internal structure of materials at multiple length scales in order to extract relevant and transferable knowledge. Data driven Process-Structure-Property (PSP) linkages provide systemic, modular and hierarchical framework for community driven curation of materials knowledge, and its transference to design and manufacturing experts. The Materials Knowledge Systems in Python project (PyMKS) is the first open source materials data science framework that can be used to create high value PSP linkages for hierarchical materials that can be leveraged by experts in materials science and engineering, manufacturing, machine learning and data science communities. This paper describes the main functions available from this repository, along with illustrations of how these can be accessed, utilized, and potentially further refined by the broader community of researchers.

Safety and control of accelerator-driven subcritical systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rief, H.; Takahashi, H.

1995-10-01

To study control and safety of accelertor driven nuclear systems, a one point kinetic model was developed and programed. It deals with fast transients as a function of reactivity insertion. Doppler feedback, and the intensity of an external neutron source. The model allows for a simultaneous calculation of an equivalent critical reactor. It was validated by a comparison with a benchmark specified by the Nuclear Energy Agency Committee of Reactor Physics. Additional features are the possibility of inserting a linear or quadratic time dependent reactivity ramp which may account for gravity induced accidents like earthquakes, the possibility to shut downmore » the external neutron source by an exponential decay law of the form exp({minus}t/{tau}), and a graphical display of the power and reactivity changes. The calculations revealed that such boosters behave quite benignly even if they are only slightly subcritical.« less

Materials Knowledge Systems in Python - A Data Science Framework for Accelerated Development of Hierarchical Materials

PubMed Central

Brough, David B; Wheeler, Daniel; Kalidindi, Surya R.

2017-01-01

There is a critical need for customized analytics that take into account the stochastic nature of the internal structure of materials at multiple length scales in order to extract relevant and transferable knowledge. Data driven Process-Structure-Property (PSP) linkages provide systemic, modular and hierarchical framework for community driven curation of materials knowledge, and its transference to design and manufacturing experts. The Materials Knowledge Systems in Python project (PyMKS) is the first open source materials data science framework that can be used to create high value PSP linkages for hierarchical materials that can be leveraged by experts in materials science and engineering, manufacturing, machine learning and data science communities. This paper describes the main functions available from this repository, along with illustrations of how these can be accessed, utilized, and potentially further refined by the broader community of researchers. PMID:28690971

Nuclear Methods for Transmutation of Nuclear Waste: Problems, Perspextives, Cooperative Research - Proceedings of the International Workshop

NASA Astrophysics Data System (ADS)

Khankhasayev, Zhanat B.; Kurmanov, Hans; Plendl, Mikhail Kh.

1996-12-01

The Table of Contents for the full book PDF is as follows: * Preface * I. Review of Current Status of Nuclear Transmutation Projects * Accelerator-Driven Systems — Survey of the Research Programs in the World * The Los Alamos Accelerator-Driven Transmutation of Nuclear Waste Concept * Nuclear Waste Transmutation Program in the Czech Republic * Tentative Results of the ISTC Supported Study of the ADTT Plutonium Disposition * Recent Neutron Physics Investigations for the Back End of the Nuclear Fuel Cycle * Optimisation of Accelerator Systems for Transmutation of Nuclear Waste * Proton Linac of the Moscow Meson Factory for the ADTT Experiments * II. Computer Modeling of Nuclear Waste Transmutation Methods and Systems * Transmutation of Minor Actinides in Different Nuclear Facilities * Monte Carlo Modeling of Electro-nuclear Processes with Nonlinear Effects * Simulation of Hybrid Systems with a GEANT Based Program * Computer Study of 90Sr and 137Cs Transmutation by Proton Beam * Methods and Computer Codes for Burn-Up and Fast Transients Calculations in Subcritical Systems with External Sources * New Model of Calculation of Fission Product Yields for the ADTT Problem * Monte Carlo Simulation of Accelerator-Reactor Systems * III. Data Basis for Transmutation of Actinides and Fission Products * Nuclear Data in the Accelerator Driven Transmutation Problem * Nuclear Data to Study Radiation Damage, Activation, and Transmutation of Materials Irradiated by Particles of Intermediate and High Energies * Radium Institute Investigations on the Intermediate Energy Nuclear Data on Hybrid Nuclear Technologies * Nuclear Data Requirements in Intermediate Energy Range for Improvement of Calculations of ADTT Target Processes * IV. Experimental Studies and Projects * ADTT Experiments at the Los Alamos Neutron Science Center * Neutron Multiplicity Distributions for GeV Proton Induced Spallation Reactions on Thin and Thick Targets of Pb and U * Solid State Nuclear Track Detector and Radiochemical Studies on the Transmutation of Nuclei Using Relativistic Heavy Ions * Experimental and Theoretical Study of Radionuclide Production on the Electronuclear Plant Target and Construction Materials Irradiated by 1.5 GeV and 130 MeV Protons * Neutronics and Power Deposition Parameters of the Targets Proposed in the ISTC Project 17 * Multicycle Irradiation of Plutonium in Solid Fuel Heavy-Water Blanket of ADS * Compound Neutron Valve of Accelerator-Driven System Sectioned Blanket * Subcritical Channel-Type Reactor for Weapon Plutonium Utilization * Accelerator Driven Molten-Fluoride Reactor with Modular Heat Exchangers on PB-BI Eutectic * A New Conception of High Power Ion Linac for ADTT * Pions and Accelerator-Driven Transmutation of Nuclear Waste? * V. Problems and Perspectives * Accelerator-Driven Transmutation Technologies for Resolution of Long-Term Nuclear Waste Concerns * Closing the Nuclear Fuel-Cycle and Moving Toward a Sustainable Energy Development * Workshop Summary * List of Participants

Microgravity Platforms

NASA Technical Reports Server (NTRS)

Del Basso, Steve

2000-01-01

The world's space agencies have been conducting microgravity research since the beginning of space flight. Initially driven by the need to understand the impact of less than- earth gravity physics on manned space flight, microgravity research has evolved into a broad class of scientific experimentation that utilizes extreme low acceleration environments. The U.S. NASA microgravity research program supports both basic and applied research in five key areas: biotechnology - focusing on macro-molecular crystal growth as well as the use of the unique space environment to assemble and grow mammalian tissue; combustion science - focusing on the process of ignition, flame propagation, and extinction of gaseous, liquid, and solid fuels; fluid physics - including aspects of fluid dynamics and transport phenomena; fundamental physics - including the study of critical phenomena, low-temperature, atomic, and gravitational physics; and materials science - including electronic and photonic materials, glasses and ceramics, polymers, and metals and alloys. Similar activities prevail within the Chinese, European, Japanese, and Russian agencies with participation from additional international organizations as well. While scientific research remains the principal objective behind these program, all hope to drive toward commercialization to sustain a long range infrastructure which .benefits the national technology and economy. In the 1997 International Space Station Commercialization Study, conducted by the Potomac Institute for Policy Studies, some viable microgravity commercial ventures were identified, however, none appeared sufficiently robust to privately fund space access at that time. Thus, government funded micro gravity research continues on an evolutionary path with revolutionary potential.

Laser driven ion accelerator

DOEpatents

Tajima, Toshiki

2006-04-18

A system and method of accelerating ions in an accelerator to optimize the energy produced by a light source. Several parameters may be controlled in constructing a target used in the accelerator system to adjust performance of the accelerator system. These parameters include the material, thickness, geometry and surface of the target.

Rod-filter-field optimization of the J-PARC RF-driven H{sup −} ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ueno, A., E-mail: akira.ueno@j-parc.jp; Ohkoshi, K.; Ikegami, K.

2015-04-08

In order to satisfy the Japan Proton Accelerator Research Complex (J-PARC) second-stage requirements of an H{sup −} ion beam of 60mA within normalized emittances of 1.5πmm•mrad both horizontally and vertically, a flat top beam duty factor of 1.25% (500μs×25Hz) and a life-time of longer than 1month, the J-PARC cesiated RF-driven H{sup −} ion source was developed by using an internal-antenna developed at the Spallation Neutron Source (SNS). Although rod-filter-field (RFF) is indispensable and one of the most beam performance dominative parameters for the RF-driven H{sup −} ion source with the internal-antenna, the procedure to optimize it is not established. Inmore » order to optimize the RFF and establish the procedure, the beam performances of the J-PARC source with various types of rod-filter-magnets (RFMs) were measured. By changing RFM’s gap length and gap number inside of the region projecting the antenna inner-diameter along the beam axis, the dependence of the H{sup −} ion beam intensity on the net 2MHz-RF power was optimized. Furthermore, the fine-tuning of RFM’s cross-section (magnetmotive force) was indispensable for easy operation with the temperature (T{sub PE}) of the plasma electrode (PE) lower than 70°C, which minimizes the transverse emittances. The 5% reduction of RFM’s cross-section decreased the time-constant to recover the cesium effects after an slightly excessive cesiation on the PE from several 10 minutes to several minutes for T{sub PE} around 60°C.« less

ADS Model in the TIRELIRE-STRATEGIE Fuel Cycle Simulation Code Application to Minor Actinides Transmutation Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garzenne, Claude; Massara, Simone; Tetart, Philippe

2006-07-01

Accelerator Driven Systems offer the advantage, thanks to the core sub-criticality, to burn highly radioactive elements such as americium and curium in a dedicated stratum, and then to avoid polluting with these elements the main part of the nuclear fleet, which is optimized for electricity production. This paper presents firstly the ADS model implemented in the fuel cycle simulation code TIRELIRE-STRATEGIE that we developed at EDF R and D Division for nuclear power scenario studies. Then we show and comment the results of TIRELIRE-STRATEGIE calculation of a transition scenario between the current French nuclear fleet, and a fast reactor fleetmore » entirely deployed towards the end of the 21. century, consistently with the EDF prospective view, with 3 options for the minor actinides management:1) vitrified with fission products to be sent to the final disposal; 2) extracted together with plutonium from the spent fuel to be transmuted in Generation IV fast reactors; 3) eventually extracted separately from plutonium to be incinerated in a ADSs double stratum. The comparison of nuclear fuel cycle material fluxes and inventories between these options shows that ADSs are not more efficient than critical fast reactors for reducing the high level waste radio-toxicity; that minor actinides inventory and fluxes in the fuel cycle are more than twice as high in case of a double ADSs stratum than in case of minor actinides transmutation in Generation IV FBRs; and that about fourteen 400 MWth ADS are necessary to incinerate minor actinides issued from a 60 GWe Generation IV fast reactor fleet, corresponding to the current French nuclear fleet installed power. (authors)« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schreiber, J.; Max-Planck-Institut für Quantenoptik Garching, Hans-Kopfermann-Str. 1, 85748 Garching bei München; Bolton, P. R.

An overview of progress and typical yields from intense laser-plasma acceleration of ions is presented. The evolution of laser-driven ion acceleration at relativistic intensities ushers prospects for improved functionality and diverse applications which can represent a varied assortment of ion beam requirements. This mandates the development of the integrated laser-driven ion accelerator system, the multiple components of which are described. Relevant high field laser-plasma science and design of controlled optimum pulsed laser irradiation on target are dominant single shot (pulse) considerations with aspects that are appropriate to the emerging petawatt era. The pulse energy scaling of maximum ion energies andmore » typical differential spectra obtained over the past two decades provide guidance for continued advancement of laser-driven energetic ion sources and their meaningful applications.« less

Heat Exchanger Can Assembly for Provision of Helium Coolant Streams for Cryomodule Testing below 2K

NASA Astrophysics Data System (ADS)

Smith, E. N.; Eichhorn, R.; Quigley, P.; Sabol, D.; Shore, C.; Widger, D.

2017-02-01

A series of heat exchanger can (HXC) assemblies have been designed, constructed and built to utilize existing 4.2 K liquefaction and compressor capabilities to provide helium gas coolant streams of 80 K, 4.5 K, and liquid from 1.6 to 2.0 K for operating cryomodules containing from one to six superconducting RF cavities built for an energy recovery linear accelerator. Designs for the largest assemblies required up to 100 W of cooling at 1.8 K with precise temperature control, especially during cool-down, and up to 2000 W at 80 K (with a 40 K temperature rise). A novel feature of these assemblies was the use of relatively inexpensive brazed stainless steel plate heat exchangers intended for room-temperature operation with water or oil, but which in practice worked well at cryogenic temperatures. The choice of operating temperatures/pressures were to provide single-phase helium flow for better control of coolant distribution in the 80 K and 4.5 K streams, to take advantage of locally elevated heat capacity near the critical point for the 4.5 K stream, and in the region below 2 K to get the best possible Q from the niobium cavities under test.

Peptide assembly-driven metal-organic framework (MOF) motors for micro electric generators

DOE PAGES

Ikezoe, Yasuhiro; Fang, Justin; Wasik, Tomasz L.; ...

2014-11-22

Peptide–metal–organic framework (Pep-MOF) motors, whose motions are driven by anisotropic surface tension gradients created via peptide self-assembly around frameworks, can rotate microscopic rotors and magnets fast enough to generate an electric power of 0.1 μW. Finally, a new rigid Pep-MOF motor can be recycled by refilling the peptide fuel into the nanopores of the MOF.

Investigations into dual-grating THz-driven accelerators

NASA Astrophysics Data System (ADS)

Wei, Y.; Ischebeck, R.; Dehler, M.; Ferrari, E.; Hiller, N.; Jamison, S.; Xia, G.; Hanahoe, K.; Li, Y.; Smith, J. D. A.; Welsch, C. P.

2018-01-01

Advanced acceleration technologies are receiving considerable interest in order to miniaturize future particle accelerators. One such technology is the dual-grating dielectric structures, which can support accelerating fields one to two orders of magnitude higher than the metal RF cavities in conventional accelerators. This opens up the possibility of enabling high accelerating gradients of up to several GV/m. This paper investigates numerically a quartz dual-grating structure which is driven by THz pulses to accelerate electrons. Geometry optimizations are carried out to achieve the trade-offs between accelerating gradient and vacuum channel gap. A realistic electron bunch available from the future Compact Linear Accelerator for Research and Applications (CLARA) is loaded into an optimized 100-period dual-grating structure for a detailed wakefield study. A THz pulse is then employed to interact with this CLARA bunch in the optimized structure. The computed beam quality is analyzed in terms of emittance, energy spread and loaded accelerating gradient. The simulations show that an accelerating gradient of 348 ± 12 MV/m with an emittance growth of 3.0% can be obtained.

Fluid driven reciprocating apparatus

DOEpatents

Whitehead, J.C.

1997-04-01

An apparatus is described comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached. 13 figs.

Fluid driven recipricating apparatus

DOEpatents

Whitehead, John C.

1997-01-01

An apparatus comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached.

Biomimetic and Aggregation-Driven Crystallization Route for Room-Temperature Material Synthesis: Growth of β-Ga2O3 Nanoparticles Using Peptide Assemblies as Nanoreactors

PubMed Central

Lee, Sang-Yup; Gao, Xueyun; Matsui, Hiroshi

2008-01-01

The room temperature synthesis of β-Ga2O3 nanocrystal was examined by coupling two biomimetic crystallization techniques, the enzymatic peptide nano-assembly templating and the aggregation-driven crystallization. The catalytic template of peptide assembly nucleated and mineralized primary β-Ga2O3 crystals, and then fused them to grow single-crystalline and monodisperse nanoparticles in the cavity of the peptide assembly at room temperature. In this work, the peptide assembly was exploited as a nano-reactor with an enzymatic functionality catalyzing the hydrolysis of gallium precursors. In addition, the characteristic ring-structure of peptide assembly is expected to provide an efficient dehydration pathway and the crystallization control over the surface tension, which are advantageous for the β-Ga2O3 crystal growth. This multifunctional peptide assembly could be applied for syntheses of a variety of nanomaterials that are kinetically difficult to grow at room temperature. PMID:17302413

Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bulanov, S. S.; Esarey, E.; Schroeder, C. B.

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes thismore » species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.« less

Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

DOE PAGES

Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; ...

2015-06-24

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes thismore » species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.« less

Tolerance to structural disorder and tunable mechanical behavior in self-assembled superlattices of polymer-grafted nanocrystals

DOE PAGES

Gu, X. Wendy; Ye, Xingchen; Koshy, David M.; ...

2017-02-27

Large, freestanding membranes with remarkably high elastic modulus ( > 10 GPa) have been fabricated through the self-Assembly of ligand-stabilized inorganic nanocrystals, even though these nanocrystals are connected only by soft organic ligands (e.g., dodecanethiol or DNA) that are not cross-linked or entangled. Recent developments in the synthesis of polymer-grafted nanocrystals have greatly expanded the library of accessible superlattice architectures,which allows superlattice mechanical behavior to be linked to specific structural features. Here, colloidal self-Assembly is used to organize polystyrene-grafted Au nanocrystals at a fluid interface to form ordered solids with sub-10-nm periodic features. We used thin-film buckling and nanoindentation tomore » evaluate the mechanical behavior of polymer-grafted nanocrystal superlattices while exploring the role of polymer structural conformation, nanocrystal packing, and superlattice dimensions. Superlattices containing 3-20 vol % Au are found to have an elastic modulus of ~6-19 GPa, and hardness of ~120-170 MPa. We also found that rapidly self-Assembled superlattices have the highest elastic modulus, despite containing significant structural defects. Polymer extension, interdigitation, and grafting density are determined to be critical parameters that govern superlattice elastic and plastic deformation.« less

Tolerance to structural disorder and tunable mechanical behavior in self-assembled superlattices of polymer-grafted nanocrystals

NASA Astrophysics Data System (ADS)

Gu, X. Wendy; Ye, Xingchen; Koshy, David M.; Vachhani, Shraddha; Hosemann, Peter; Alivisatos, A. Paul

2017-03-01

Large, freestanding membranes with remarkably high elastic modulus (>10 GPa) have been fabricated through the self-assembly of ligand-stabilized inorganic nanocrystals, even though these nanocrystals are connected only by soft organic ligands (e.g., dodecanethiol or DNA) that are not cross-linked or entangled. Recent developments in the synthesis of polymer-grafted nanocrystals have greatly expanded the library of accessible superlattice architectures, which allows superlattice mechanical behavior to be linked to specific structural features. Here, colloidal self-assembly is used to organize polystyrene-grafted Au nanocrystals at a fluid interface to form ordered solids with sub-10-nm periodic features. Thin-film buckling and nanoindentation are used to evaluate the mechanical behavior of polymer-grafted nanocrystal superlattices while exploring the role of polymer structural conformation, nanocrystal packing, and superlattice dimensions. Superlattices containing 3-20 vol % Au are found to have an elastic modulus of ˜6-19 GPa, and hardness of ˜120-170 MPa. We find that rapidly self-assembled superlattices have the highest elastic modulus, despite containing significant structural defects. Polymer extension, interdigitation, and grafting density are determined to be critical parameters that govern superlattice elastic and plastic deformation.

Regulated assembly and disassembly of the yeast telomerase quaternary complex

PubMed Central

Tucey, Timothy M.

2014-01-01

The enzyme telomerase, which elongates chromosome termini, is a critical factor in determining long-term cellular proliferation and tissue renewal. Hence, even small differences in telomerase levels can have substantial consequences for human health. In budding yeast, telomerase consists of the catalytic Est2 protein and two regulatory subunits (Est1 and Est3) in association with the TLC1 RNA, with each of the four subunits essential for in vivo telomerase function. We show here that a hierarchy of assembly and disassembly results in limiting amounts of the quaternary complex late in the cell cycle, following completion of DNA replication. The assembly pathway, which is driven by interaction of the Est3 telomerase subunit with a previously formed Est1–TLC1–Est2 preassembly complex, is highly regulated, involving Est3-binding sites on both Est2 and Est1 as well as an interface on Est3 itself that functions as a toggle switch. Telomerase subsequently disassembles by a mechanistically distinct pathway due to dissociation of the catalytic subunit from the complex in every cell cycle. The balance between the assembly and disassembly pathways, which dictate the levels of the active holoenzyme in the cell, reveals a novel mechanism by which telomerase (and hence telomere homeostasis) is regulated. PMID:25240060

Nonlinear effects in the bounded dust-vortex flow in plasma

NASA Astrophysics Data System (ADS)

Laishram, Modhuchandra; Sharma, Devendra; Chattopdhyay, Prabal K.; Kaw, Predhiman K.

2017-03-01

The vortex structures in a cloud of electrically suspended dust in a streaming plasma constitutes a driven system with a rich nonlinear flow regime. Experimentally recovered toroidal formations of this system have motivated study of its volumetrically driven-dissipative vortex flow dynamics using two-dimensional hydrodynamics in the incompressible Navier-Stokes regime. Nonlinear equilibrium solutions are obtained for this system where a nonuniformly driven two-dimensional dust flow exhibits distinct regions of localized accelerations and strong friction caused by stationary fluids at the confining boundaries resisting the dust flow. In agreement with observations in experiments, it is demonstrated that the nonlinear effects appear in the limit of small viscosity, where the primary vortices form scaling with the most dominant spatial scales of the domain topology and develop separated virtual boundaries along their periphery. This separation is triggered beyond a critical dust viscosity that signifies a structural bifurcation. Emergence of uniform vorticity core and secondary vortices with a newer level of identical dynamics highlights the applicability of the studied dynamics to gigantic vortex flows, such as the Jovian great red spot, to microscopic biophysical intracellular activity.

Simulation of sloshing dynamics induced forces and torques actuated on dewar container driven by gravity gradient and jitter accelerations in microgravity

NASA Technical Reports Server (NTRS)

Hung, R. J.; Pan, H. L.

1993-01-01

Some experimental spacecraft use superconducting sensors for gyro read-out and so must be maintained at a very low temperature. The boil-off from the cryogenic liquid used to cool the sensors can also be used, as the Gravity Probe B (GP-B) spacecraft does, as propellant to maintain attitude control and drag-free operation of the spacecraft. The cryogenic liquid for such spacecraft is, however, susceptible to both slosh-like motion and non-axisymmetric configurations under the influence of various kinds of gravity jitter and gravity gradient accelerations. Hence, it is important to quantify the magnitude of the liquid-induced perturbations on the spacecraft. We use the example of the GP-B to investigate such perturbations by numerical simulations. For this spacecraft disturbances can be imposed on the liquid by atmospheric drag, spacecraft attitude control maneuvers, and the earth's gravity gradient. More generally, onboard machinery vibrations and crew motion can also create disturbances. Recent studies suggest that high frequency disturbances are relatively unimportant in causing liquid motions in comparison to low frequency ones. The results presented here confirm this conclusion. After an initial calibration period, the GP-B spacecraft rotates in orbit at 0.1 rpm about the tank symmetry axis. For this rotation rate, the equilibrium liquid free surface shape is a 'doughnut' configuration for all residual gravity levels of 10(exp -6) g(sub 0) or less, as shown by experiments and by numerical simulations; furthermore, the superfluid behavior of the 1.8 K liquid helium used in GP-B eliminates temperature gradients and therefore such effects as Marangoni convection do not have to be considered. Classical fluid dynamics theory is used as the basis of the numerical simulations here, since Mason's experiments show that the theory is applicable for cryogenic liquid helium in large containers. To study liquid responses to various disturbances, we investigate and simulate three levels of gravity jitter (10(exp -6), 10(exp -7), and 10(exp -8) g(sub 0)) each at three predominant frequencies (0.1, 1.0, and 10 Hz), combined with a gravity gradient appropriate for the GP-B orbit. Dynamical evolution of sloshing dynamics excited fluid forces and torque fluctuations exerted on the dewar container driven by the combined gravity gradient and jitter accelerations are also investigated and simulated.

Alfven Waves Underlying Ionospheric Destabilization: Ground-Based Observations

NASA Astrophysics Data System (ADS)

Hirsch, Michael

During geomagnetic storms, terawatts of power in the million mile-per-hour solar wind pierce the Earth's magnetosphere. Geomagnetic storms and substorms create transverse magnetic waves known as Alfven waves. In the auroral acceleration region, Alfven waves accelerate electrons up to one-tenth the speed of light via wave-particle interactions. These inertial Alfven wave (IAW) accelerated electrons are imbued with sub-100 meter structure perpendicular to geomagnetic field B. The IAW electric field parallel to B accelerates electrons up to about 10 keV along B. The IAW dispersion relation quantifies the precipitating electron striation observed with high-speed cameras as spatiotemporally dynamic fine structured aurora. A network of tightly synchronized tomographic auroral observatories using model based iterative reconstruction (MBIR) techniques were developed in this dissertation. The TRANSCAR electron penetration model creates a basis set of monoenergetic electron beam eigenprofiles of auroral volume emission rate for the given location and ionospheric conditions. Each eigenprofile consists of nearly 200 broadband line spectra modulated by atmospheric attenuation, bandstop filter and imager quantum efficiency. The L-BFGS-B minimization routine combined with sub-pixel registered electron multiplying CCD video stream at order 10 ms cadence yields estimates of electron differential number flux at the top of the ionosphere. Our automatic data curation algorithm reduces one terabyte/camera/day into accurate MBIR-processed estimates of IAW-driven electron precipitation microstructure. This computer vision structured auroral discrimination algorithm was developed using a multiscale dual-camera system observing a 175 km and 14 km swath of sky simultaneously. This collective behavior algorithm exploits the "swarm" behavior of aurora, detectable even as video SNR approaches zero. A modified version of the algorithm is applied to topside ionospheric radar at Mars and broadcast FM passive radar. The fusion of data from coherent radar backscatter and optical data at order 10 ms cadence confirms and further quantifies the relation of strong Langmuir turbulence and streaming plasma upflows in the ionosphere with the finest spatiotemporal auroral dynamics associated with IAW acceleration. The software programs developed in this dissertation solve the century-old problem of automatically discriminating finely structured aurora from other forms and pushes the observational wave-particle science frontiers forward.

Initial Investigation of Wave Impact Load Transfer Through Shock Isolation Seats in High Speed Craft

DTIC Science & Technology

2013-08-31

12 Hz to 14 Hz is caused by the relative motions of the spring-damper assembly between the deck and the seat pan. In the deck acceleration signal the...caused by the oscillation of the seat assembly. In other words, 12 Hz to 14 Hz motions of the seat assembly fed back into the deck structure as in a...accelerations are based on use of a 10 Hz low- pass filter to capture only the dominant rigid body impacts observed in Figure 3 at less than 2 Hz. The seat

Self-folding micropatterned polymeric containers.

PubMed

Azam, Anum; Laflin, Kate E; Jamal, Mustapha; Fernandes, Rohan; Gracias, David H

2011-02-01

We demonstrate self-folding of precisely patterned, optically transparent, all-polymeric containers and describe their utility in mammalian cell and microorganism encapsulation and culture. The polyhedral containers, with SU-8 faces and biodegradable polycaprolactone (PCL) hinges, spontaneously assembled on heating. Self-folding was driven by a minimization of surface area of the liquefying PCL hinges within lithographically patterned two-dimensional (2D) templates. The strategy allowed for the fabrication of containers with variable polyhedral shapes, sizes and precisely defined porosities in all three dimensions. We provide proof-of-concept for the use of these polymeric containers as encapsulants for beads, chemicals, mammalian cells and bacteria. We also compare accelerated hinge degradation rates in alkaline solutions of varying pH. These optically transparent containers resemble three-dimensional (3D) micro-Petri dishes and can be utilized to sustain, monitor and deliver living biological components.

Monte Carlo simulation of the operational quantities at the realistic mixed neutron-photon radiation fields CANEL and SIGMA.

PubMed

Lacoste, V; Gressier, V

2007-01-01

The Institute for Radiological Protection and Nuclear Safety owns two facilities producing realistic mixed neutron-photon radiation fields, CANEL, an accelerator driven moderator modular device, and SIGMA, a graphite moderated americium-beryllium assembly. These fields are representative of some of those encountered at nuclear workplaces, and the corresponding facilities are designed and used for calibration of various instruments, such as survey meters, personal dosimeters or spectrometric devices. In the framework of the European project EVIDOS, irradiations of personal dosimeters were performed at CANEL and SIGMA. Monte Carlo calculations were performed to estimate the reference values of the personal dose equivalent at both facilities. The Hp(10) values were calculated for three different angular positions, 0 degrees, 45 degrees and 75 degrees, of an ICRU phantom located at the position of irradiation.

Formation of the 110-K superconducting phase in Pb-doped Bi-Sr-Ca-Cu-O thin films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kula, W.; Sobolewski, R.; Gorecka, J.

1991-09-15

Investigation of the 110-K Bi{sub 2}Sr{sub 2}Ca{sub 2}Cu{sub 3}O{sub {ital x}} phase formation in superconducting thin films of Bi-based cuprates is reported. The films were dc magnetron sputtered from single Bi(Pb)-Sr-Ca-Cu-O targets of various stoichiometries, and subsequently annealed in air at high temperatures. The influence of the initial Pb content, annealing conditions, as well as the substrate material on the growth of the 110-K phase was investigated. We found that the films, fully superconducting above 100 K could be reproducibly fabricated on various dielectric substrates from Pb-rich targets by optimizing annealing conditions for each initial Pb/Bi ratio. Heavy Pb dopingmore » considerably accelerated formation of the 110-K phase, reducing the film annealing time to less than 1 h. Films containing, according to the x-ray measurement, more than 90% of the 110-K phase were obtained on MgO substrates, after sputtering from the Bi{sub 2}Pb{sub 2.5}Sr{sub 2}Ca{sub 2.15}Cu{sub 3.3}O{sub {ital x}} target and annealing in air for 1 h at 870 {degree}C. The films were {ital c}-axis oriented, with 4.5-K-wide superconducting transition, and zero resistivity at 106 K. Their critical current density was 2 {times} 10{sup 2} A/cm{sup 2} at 90 K, and above 10{sup 4} A/cm{sup 2} below 60 K. The growth of the 110-K phase on epitaxial substrates, such as CaNdAlO{sub 4} and SrTiO{sub 3}, was considerably deteriorated, and the presence of the 80- and 10-K phases was detected. Nevertheless, the best films deposited on these substrates were fully superconducting at 104 K and exhibited critical current densities above 2 {times} 10{sup 5} A/cm{sup 2} below 60 K{minus}one order of magnitude greater than the films deposited on MgO.« less

Criticality Safety Evaluation Report CSER-96-019 for Spent Nuclear Fuel (SNF) Processing and Storage Facilities Multi Canister Overpack (MCO)

DOE Office of Scientific and Technical Information (OSTI.GOV)

KESSLER, S.F.

This criticality evaluation is for Spent N Reactor fuel unloaded from the existing canisters in both KE and KW Basins, and loaded into multiple canister overpack (MCO) containers with specially built baskets containing a maximum of either 54 Mark IV or 48 Mark IA fuel assemblies. The criticality evaluations include loading baskets into the cask-MCO, operation at the Cold Vacuum Drying Facility,a nd storage in the Canister Storage Building. Many conservatisms have been built into this analysis, the primary one being the selection of the K{sub eff} = 0.95 criticality safety limit. This revision incorporates the analyses for the sampling/weldmore » station in the Canister Storage Building and additional analysis of the MCO during the draining at CVDF. Additional discussion of the scrap basket model was added to show why the addition of copper divider plates was not included in the models.« less

Design of a beam shaping assembly and preliminary modelling of a treatment room for accelerator-based BNCT at CNEA.

PubMed

Burlon, A A; Girola, S; Valda, A A; Minsky, D M; Kreiner, A J; Sánchez, G

2011-12-01

This work reports on the characterisation of a neutron beam shaping assembly (BSA) prototype and on the preliminary modelling of a treatment room for BNCT within the framework of a research programme for the development and construction of an accelerator-based BNCT irradiation facility in Buenos Aires, Argentina. The BSA prototype constructed has been characterised by means of MCNP simulations as well as a set of experimental measurements performed at the Tandar accelerator at the National Atomic Energy Commission of Argentina. Copyright © 2011 Elsevier Ltd. All rights reserved.

Dense blocks of energetic ions driven by multi-petawatt lasers

PubMed Central

Weng, S. M.; Liu, M.; Sheng, Z. M.; Murakami, M.; Chen, M.; Yu, L. L.; Zhang, J.

2016-01-01

Laser-driven ion accelerators have the advantages of compact size, high density, and short bunch duration over conventional accelerators. Nevertheless, it is still challenging to simultaneously enhance the yield and quality of laser-driven ion beams for practical applications. Here we propose a scheme to address this challenge via the use of emerging multi-petawatt lasers and a density-modulated target. The density-modulated target permits its ions to be uniformly accelerated as a dense block by laser radiation pressure. In addition, the beam quality of the accelerated ions is remarkably improved by embedding the target in a thick enough substrate, which suppresses hot electron refluxing and thus alleviates plasma heating. Particle-in-cell simulations demonstrate that almost all ions in a solid-density plasma of a few microns can be uniformly accelerated to about 25% of the speed of light by a laser pulse at an intensity around 1022 W/cm2. The resulting dense block of energetic ions may drive fusion ignition and more generally create matter with unprecedented high energy density. PMID:26924793

Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of [alpha]- and PPII-helices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larson, Matthew R.; Rajashankar, Kanagalaghatta R.; Patel, Manisha H.

2010-08-18

Streptococcus mutans antigen I/II (AgI/II) is a cell surface-localized protein adhesin that interacts with salivary components within the salivary pellicle. AgI/II contributes to virulence and has been studied as an immunological and structural target, but a fundamental understanding of its underlying architecture has been lacking. Here we report a high-resolution (1.8 {angstrom}) crystal structure of the A{sub 3}VP{sub 1} fragment of S. mutans AgI/II that demonstrates a unique fibrillar form (155 {angstrom}) through the interaction of two noncontiguous regions in the primary sequence. The A{sub 3} repeat of the alanine-rich domain adopts an extended {alpha}-helix that intertwines with the P{submore » 1} repeat polyproline type II (PPII) helix to form a highly extended stalk-like structure heretofore unseen in prokaryotic or eukaryotic protein structures. Velocity sedimentation studies indicate that full-length AgI/II that contains three A/P repeats extends over 50 nanometers in length. Isothermal titration calorimetry revealed that the high-affinity association between the A{sub 3} and P{sub 1} helices is enthalpically driven. Two distinct binding sites on AgI/II to the host receptor salivary agglutinin (SAG) were identified by surface plasmon resonance (SPR). The current crystal structure reveals that AgI/II family proteins are extended fibrillar structures with the number of alanine- and proline-rich repeats determining their length.« less

C{sub 60}-dyad aggregates: Self-organized structures in aqueous solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guskova, O. A., E-mail: guskova@ipfdd.de, E-mail: s.raovaranasi@uq.edu.au; Varanasi, S. R., E-mail: guskova@ipfdd.de, E-mail: s.raovaranasi@uq.edu.au; Sommer, J.-U.

2014-10-14

Extensive full-atomistic molecular dynamics simulations are performed to study the self-organization of C{sub 60}-fullerene dyad molecules in water, namely phenyl-C{sub 61}-butyric acid methyl ester and fulleropyrrolidines, which have two elements of ordering, the hydrophobic fullerene cage and the hydrophilic/ionic group. While pristine fullerene or phenyl-C{sub 61}-butyric acid methyl ester forms spherical droplets in order to minimize the surface tension, the amphiphilic nature of charged solute molecules leads to the formation of supramolecular assemblies having cylindrical shape driven by charge repulsion between the ionic groups located on the surface of the aggregates. We show that formation of non-spherical micelles is themore » geometrical consequence if the fullerene derivatives are considered as surfactants where the ionized groups are only hydrophilic unit. The agglomeration behavior of fullerenes is evaluated by determining sizes of the clusters, solvent accessible surface areas, and shape parameters. By changing the size of the counterions from chloride over iodide to perchlorate we find a thickening of the cylinder-like structures which can be explained by stronger condensation of larger ions and thus partial screening of the charge repulsion on the cluster surface. The reason for the size dependence of counterion condensation is the formation of a stronger hydration shell in case of small ions which in turn are repelled from the fullerene aggregates. Simulations are also in good agreement with the experimentally observed morphologies of decorated C{sub 60}-nanoparticles.« less

Method of preparing a positive electrode for an electrochemical cell

DOEpatents

Tomczuk, Zygmunt

1979-01-01

A method of preparing an electrochemical cell including a metal sulfide as the positive electrode reactant and lithium alloy as the negative electrochemical reactant with an alkali metal, molten salt electrolyte is disclosed which permits the assembly to be accomplished in air. The electrode reactants are introduced in the most part as a sulfide of lithium and the positive electrode metal in a single-phase compound. For instance, Li.sub.2 FeS.sub.2 is a single-phase compound that is produced by the reaction of Li.sub.2 S and FeS. This compound is an intermediate in the positive electrode cycle from FeS.sub.2 to Fe and Li.sub.2 S. Its use minimizes volumetric changes from the assembled to the charged and discharged conditions of the electrode and minimizes electrode material interaction with air and moisture during assembly.

Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn 4CaO 5-cluster in photosystem II

DOE PAGES

Zhang, Miao; Bommer, Martin; Chatterjee, Ruchira; ...

2017-07-18

In plants, algae and cyanobacteria, Photosystem II (PSII) catalyzes the light-driven splitting of water at a protein-bound Mn 4CaO 5-cluster, the water-oxidizing complex (WOC). In the photosynthetic organisms, the light-driven formation of the WOC from dissolved metal ions is a key process because it is essential in both initial activation and continuous repair of PSII. Structural information is required for understanding of this chaperone-free metal-cluster assembly. For the first time, we obtained a structure of PSII from Thermosynechococcus elongatus without the Mn 4CaO 5-cluster. Surprisingly, cluster-removal leaves the positions of all coordinating amino acid residues and most nearby water moleculesmore » largely unaffected, resulting in a pre-organized ligand shell for kinetically competent and error-free photo-assembly of the Mn 4CaO 5-cluster. First experiments initiating (i) partial disassembly and (ii) partial re-assembly after complete depletion of the Mn4CaO5-cluster agree with a specific bi-manganese cluster, likely a di-µ-oxo bridged pair of Mn(III) ions, as an assembly intermediate.« less

Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn4CaO5-cluster in photosystem II.

PubMed

Zhang, Miao; Bommer, Martin; Chatterjee, Ruchira; Hussein, Rana; Yano, Junko; Dau, Holger; Kern, Jan; Dobbek, Holger; Zouni, Athina

2017-07-18

In plants, algae and cyanobacteria, Photosystem II (PSII) catalyzes the light-driven splitting of water at a protein-bound Mn 4 CaO 5 -cluster, the water-oxidizing complex (WOC). In the photosynthetic organisms, the light-driven formation of the WOC from dissolved metal ions is a key process because it is essential in both initial activation and continuous repair of PSII. Structural information is required for understanding of this chaperone-free metal-cluster assembly. For the first time, we obtained a structure of PSII from Thermosynechococcus elongatus without the Mn 4 CaO 5 -cluster. Surprisingly, cluster-removal leaves the positions of all coordinating amino acid residues and most nearby water molecules largely unaffected, resulting in a pre-organized ligand shell for kinetically competent and error-free photo-assembly of the Mn 4 CaO 5 -cluster. First experiments initiating (i) partial disassembly and (ii) partial re-assembly after complete depletion of the Mn 4 CaO 5 -cluster agree with a specific bi-manganese cluster, likely a di-µ-oxo bridged pair of Mn(III) ions, as an assembly intermediate.

Measurements and analysis of leakage neutron spectra from multiple-slab sample assemblies comprising W,U,C, and CH2 with D-T neutron irradiation.

PubMed

Luo, F; Han, R; Chen, Z; Nie, Y; Sun, Q; Shi, F; Zhang, S; Tian, G; Song, L; Ruan, X; Ye, M Y

2018-07-01

The accelerator driven subcritical system (ADS) is regarded as a safe and clean nuclear power system, which can be used for the transmutation of nuclear waste and the breeding of nuclear fuel. In this study, in order to validate nuclear data and the neutron transportation performance of the materials related to ADS, we measured the leakage neutron spectra from multiple-slab sample assemblies using 14.8 MeV D-T neutrons. Two types of assemblies comprising A-1 (W+U+C+CH 2 ) and A-2 (U+C+CH 2 ) were both built up gradually starting with the first wall. The measured spectra were compared with those calculated using the Monte Carlo code neutron transport coed (MCNP)-4C. A comparison of the results showed that the experimental leakage neutron spectra for both A-1 or A-2 were reproduced well by the three evaluated nuclear data libraries with discrepancies of less than 15% (A-1) and 12% (A-2), except when below 3 MeV. For 2-cm and 5-cm uranium samples, the CENDL-3.1 calculations exhibited large discrepancies in the energy range of 2-8 MeV and above 13 MeV. Thus, the CENDL-3.1 library for uranium should be reevaluated, especially around this energy range. It was significant that the leakage neuron spectra changed clearly when the latest material layer was added during the building of assemblies A-1 and A-2. Copyright © 2018 Elsevier Ltd. All rights reserved.

Status of high temperature superconductor development for accelerator magnets

NASA Technical Reports Server (NTRS)

Hirabayashi, H.

1995-01-01

High temperature superconductors are still under development for various applications. As far as conductors for magnets are concerned, the development has just been started. Small coils wound by silver sheathed Bi-2212 and Bi-2223 oxide conductors have been reported by a few authors. Essential properties of high T(sub c) superconductors like pinning force, coherent length, intergrain coupling, weak link, thermal property, AC loss and mechanical strength are still not sufficiently understandable. In this talk, a review is given with comparison between the present achievement and the final requirement for high T(sub c) superconductors, which could be particularly used in accelerator magnets. Discussions on how to develop high T(sub c) superconductors for accelerator magnets are included with key parameters of essential properties. A proposal of how to make a prototype accelerator magnet with high T(sub c) superconductors with prospect for future development is also given.

Probing temperature-driven flow lines in a gated two-dimensional electron gas with tunable spin-splitting.

PubMed

Wang, Yi-Ting; Kim, Gil-Ho; Huang, C F; Lo, Shun-Tsung; Chen, Wei-Jen; Nicholls, J T; Lin, Li-Hung; Ritchie, D A; Chang, Y H; Liang, C-T; Dolan, B P

2012-10-10

We study the temperature flow of conductivities in a gated GaAs two-dimensional electron gas (2DEG) containing self-assembled InAs dots and compare the results with recent theoretical predictions. By changing the gate voltage, we are able to tune the 2DEG density and thus vary disorder and spin-splitting. Data for both the spin-resolved and spin-degenerate phase transitions are presented, the former collapsing to the latter with decreasing gate voltage and/or decreasing spin-splitting. The experimental results support a recent theory, based on modular symmetry, which predicts how the critical Hall conductivity varies with spin-splitting.

A review of the current state-of-the-art methodology for handling bias and uncertainty in performing criticality safety evaluations. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Disney, R.K.

1994-10-01

The methodology for handling bias and uncertainty when calculational methods are used in criticality safety evaluations (CSE`s) is a rapidly evolving technology. The changes in the methodology are driven by a number of factors. One factor responsible for changes in the methodology for handling bias and uncertainty in CSE`s within the overview of the US Department of Energy (DOE) is a shift in the overview function from a ``site`` perception to a more uniform or ``national`` perception. Other causes for change or improvement in the methodology for handling calculational bias and uncertainty are; (1) an increased demand for benchmark criticalsmore » data to expand the area (range) of applicability of existing data, (2) a demand for new data to supplement existing benchmark criticals data, (3) the increased reliance on (or need for) computational benchmarks which supplement (or replace) experimental measurements in critical assemblies, and (4) an increased demand for benchmark data applicable to the expanded range of conditions and configurations encountered in DOE site restoration and remediation.« less

Experimental and Simulated Characterization of a Beam Shaping Assembly for Accelerator- Based Boron Neutron Capture Therapy (AB-BNCT)

NASA Astrophysics Data System (ADS)

Burlon, Alejandro A.; Girola, Santiago; Valda, Alejandro A.; Minsky, Daniel M.; Kreiner, Andrés J.

2010-08-01

In the frame of the construction of a Tandem Electrostatic Quadrupole Accelerator facility devoted to the Accelerator-Based Boron Neutron Capture Therapy, a Beam Shaping Assembly has been characterized by means of Monte-Carlo simulations and measurements. The neutrons were generated via the 7Li(p, n)7Be reaction by irradiating a thick LiF target with a 2.3 MeV proton beam delivered by the TANDAR accelerator at CNEA. The emerging neutron flux was measured by means of activation foils while the beam quality and directionality was evaluated by means of Monte Carlo simulations. The parameters show compliance with those suggested by IAEA. Finally, an improvement adding a beam collimator has been evaluated.

Switching Characteristics of a 4H-SiC Based Bipolar Junction Transistor to 200 C

NASA Technical Reports Server (NTRS)

Niedra, Janis M.

2006-01-01

Static curves and resistive load switching characteristics of a 600 V, 4 A rated, SiC-based NPN bipolar power transistor (BJT) were observed at selected temperatures from room to 200 C. All testing was done in a pulse mode at low duty cycle (approx.0.1 percent). Turn-on was driven by an adjustable base current pulse and turn-off was accelerated by a negative base voltage pulse of 7 V. These base drive signals were implemented by 850 V, gated power pulsers, having rise-times of roughly 10 ns, or less. Base charge sweep-out with a 7 V negative pulse did not produce the large reverse base current pulse seen in a comparably rated Si-based BJT. This may be due to a very low charge storage time. The decay of the collector current was more linear than its exponential-like rise. Switching observations were done at base drive currents (I(sub B)) up to 400 mA and collector currents (I(sub C)) up to 4 A, using a 100 Omega non-inductive load. At I(sub B) = 400 mA and I(sub C) = 4 A, turn-on times typically varied from 80 to 94 ns, over temperatures from 23 to 200 C. As expected, lowering the base drive greatly extended the turn-on time. Similarly, decreasing the load current to I(sub C) = 1 A with I(sub B) = 400 mA produced turn-on times as short as 34 ns. Over the 23 to 200 C range, with I(sub B) = 400 mA and I(sub C) = 4 A, turn-off times were in the range of 72 to 84 ns with the 7 V sweep-out.

Self-injection of electrons in a laser-wakefield accelerator by using longitudinal density ripple

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dahiya, Deepak; Sharma, A. K.; Sajal, Vivek

By introducing a longitudinal density ripple (periodic modulation in background plasma density), we demonstrate self-injection of electrons in a laser-wakefield accelerator. The wakefield driven plasma wave, in presence of density ripple excites two side band waves of same frequency but different wave numbers. One of these side bands, having smaller phase velocity compared to wakefield driven plasma wave, preaccelerates the background plasma electrons. Significant number of these preaccelerated electrons get trapped in the laser-wakefield and further accelerated to higher energies.

Benchmarking shielding simulations for an accelerator-driven spallation neutron source

DOE PAGES

Cherkashyna, Nataliia; Di Julio, Douglas D.; Panzner, Tobias; ...

2015-08-09

The shielding at an accelerator-driven spallation neutron facility plays a critical role in the performance of the neutron scattering instruments, the overall safety, and the total cost of the facility. Accurate simulation of shielding components is thus key for the design of upcoming facilities, such as the European Spallation Source (ESS), currently in construction in Lund, Sweden. In this paper, we present a comparative study between the measured and the simulated neutron background at the Swiss Spallation Neutron Source (SINQ), at the Paul Scherrer Institute (PSI), Villigen, Switzerland. The measurements were carried out at several positions along the SINQ monolithmore » wall with the neutron dosimeter WENDI-2, which has a well-characterized response up to 5 GeV. The simulations were performed using the Monte-Carlo radiation transport code Geant4, and include a complete transport from the proton beam to the measurement locations in a single calculation. An agreement between measurements and simulations is about a factor of 2 for the points where the measured radiation dose is above the background level, which is a satisfactory result for such simulations spanning many energy regimes, different physics processes and transport through several meters of shielding materials. The neutrons contributing to the radiation field emanating from the monolith were confirmed to originate from neutrons with energies above 1 MeV in the target region. The current work validates Geant4 as being well suited for deep-shielding calculations at accelerator-based spallation sources. We also extrapolate what the simulated flux levels might imply for short (several tens of meters) instruments at ESS.« less

Community-level education accelerates the cultural evolution of fertility decline.

PubMed

Colleran, Heidi; Jasienska, Grazyna; Nenko, Ilona; Galbarczyk, Andrzej; Mace, Ruth

2014-03-22

Explaining why fertility declines as populations modernize is a profound theoretical challenge. It remains unclear whether the fundamental drivers are economic or cultural in nature. Cultural evolutionary theory suggests that community-level characteristics, for example average education, can alter how low-fertility preferences are transmitted and adopted. These assumptions have not been empirically tested. Here, we show that community-level education accelerates fertility decline in a way that is neither predicted by individual characteristics, nor by the level of economic modernization in a population. In 22 high-fertility communities in Poland, fertility converged on a smaller family size as average education in the community increased-indeed community-level education had a larger impact on fertility decline than did individual education. This convergence was not driven by educational levels being more homogeneous, but by less educated women having fewer children than expected, and more highly educated social networks, when living among more highly educated neighbours. The average level of education in a community may influence the social partners women interact with, both within and beyond their immediate social environments, altering the reproductive norms they are exposed to. Given a critical mass of highly educated women, less educated neighbours may adopt their reproductive behaviour, accelerating the pace of demographic transition. Individual characteristics alone cannot capture these dynamics and studies relying solely on them may systematically underestimate the importance of cultural transmission in driving fertility declines. Our results are inconsistent with a purely individualistic, rational-actor model of fertility decline and suggest that optimization of reproduction is partly driven by cultural dynamics beyond the individual.

Community-level education accelerates the cultural evolution of fertility decline

PubMed Central

Colleran, Heidi; Jasienska, Grazyna; Nenko, Ilona; Galbarczyk, Andrzej; Mace, Ruth

2014-01-01

Explaining why fertility declines as populations modernize is a profound theoretical challenge. It remains unclear whether the fundamental drivers are economic or cultural in nature. Cultural evolutionary theory suggests that community-level characteristics, for example average education, can alter how low-fertility preferences are transmitted and adopted. These assumptions have not been empirically tested. Here, we show that community-level education accelerates fertility decline in a way that is neither predicted by individual characteristics, nor by the level of economic modernization in a population. In 22 high-fertility communities in Poland, fertility converged on a smaller family size as average education in the community increased—indeed community-level education had a larger impact on fertility decline than did individual education. This convergence was not driven by educational levels being more homogeneous, but by less educated women having fewer children than expected, and more highly educated social networks, when living among more highly educated neighbours. The average level of education in a community may influence the social partners women interact with, both within and beyond their immediate social environments, altering the reproductive norms they are exposed to. Given a critical mass of highly educated women, less educated neighbours may adopt their reproductive behaviour, accelerating the pace of demographic transition. Individual characteristics alone cannot capture these dynamics and studies relying solely on them may systematically underestimate the importance of cultural transmission in driving fertility declines. Our results are inconsistent with a purely individualistic, rational-actor model of fertility decline and suggest that optimization of reproduction is partly driven by cultural dynamics beyond the individual. PMID:24500166

Hierarchical algorithms for modeling the ocean on hierarchical architectures

NASA Astrophysics Data System (ADS)

Hill, C. N.

2012-12-01

This presentation will describe an approach to using accelerator/co-processor technology that maps hierarchical, multi-scale modeling techniques to an underlying hierarchical hardware architecture. The focus of this work is on making effective use of both CPU and accelerator/co-processor parts of a system, for large scale ocean modeling. In the work, a lower resolution basin scale ocean model is locally coupled to multiple, "embedded", limited area higher resolution sub-models. The higher resolution models execute on co-processor/accelerator hardware and do not interact directly with other sub-models. The lower resolution basin scale model executes on the system CPU(s). The result is a multi-scale algorithm that aligns with hardware designs in the co-processor/accelerator space. We demonstrate this approach being used to substitute explicit process models for standard parameterizations. Code for our sub-models is implemented through a generic abstraction layer, so that we can target multiple accelerator architectures with different programming environments. We will present two application and implementation examples. One uses the CUDA programming environment and targets GPU hardware. This example employs a simple non-hydrostatic two dimensional sub-model to represent vertical motion more accurately. The second example uses a highly threaded three-dimensional model at high resolution. This targets a MIC/Xeon Phi like environment and uses sub-models as a way to explicitly compute sub-mesoscale terms. In both cases the accelerator/co-processor capability provides extra compute cycles that allow improved model fidelity for little or no extra wall-clock time cost.

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance

PubMed Central

Liu, Yudong; Seto, Nickie L; Carmona-Rivera, Carmelo; Kaplan, Mariana J

2018-01-01

Objectives Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally introduce multiple risk alleles, thereby adding additional confounding factors. In the induced lupus models, the role of TLR9 remains unclear. In the present study, we explored the role of an imbalance between TLR7 and TLR9 pathways in the pathogenesis of lupus and its associated vasculopathy using the imiquimod model in TLR9 KO/B6 background. Methods Wild type (WT) and Tlr9-/- mice were epicutaneously treated with imiquimod cream 5% on both ears three times per week for indicated times. At euthanasia, mice were analysed for organ involvement, endothelium-dependent vasorelaxation, serum autoantibodies, and innate and adaptive immune responses. Results Compared with the lupus-like phenotype that develops in imiquimod-treated WT mice, Tlr9-/- mice exposed to imiquimod have increased severity of autoimmunity features and inflammatory phenotype that develops at earlier stages. These abnormalities are characterised by enhanced TLR7 expression and immune activation, increased immune complex deposition, Th1 T cells and dendritic cell kidney infiltration and significant impairments in endothelial function. Modulation of TLR7 expression was observed in the Tlr9-/- mice. Conclusions These findings further underscore the protective role of TLR9 in TLR7-driven autoimmunity and also in the development of vasculopathy, further strengthening the importance of tightly manipulating TLRs in putative therapeutic strategies. This study provides a new model of accelerated lupus phenotype driven by danger-associated molecular patterns. PMID:29765617

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance.

PubMed

Liu, Yudong; Seto, Nickie L; Carmona-Rivera, Carmelo; Kaplan, Mariana J

2018-01-01

Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally introduce multiple risk alleles, thereby adding additional confounding factors. In the induced lupus models, the role of TLR9 remains unclear. In the present study, we explored the role of an imbalance between TLR7 and TLR9 pathways in the pathogenesis of lupus and its associated vasculopathy using the imiquimod model in TLR9 KO/B6 background. Wild type (WT) and Tlr9 -/- mice were epicutaneously treated with imiquimod cream 5% on both ears three times per week for indicated times. At euthanasia, mice were analysed for organ involvement, endothelium-dependent vasorelaxation, serum autoantibodies, and innate and adaptive immune responses. Compared with the lupus-like phenotype that develops in imiquimod-treated WT mice, Tlr9 -/- mice exposed to imiquimod have increased severity of autoimmunity features and inflammatory phenotype that develops at earlier stages. These abnormalities are characterised by enhanced TLR7 expression and immune activation, increased immune complex deposition, Th1 T cells and dendritic cell kidney infiltration and significant impairments in endothelial function. Modulation of TLR7 expression was observed in the Tlr9 -/- mice. These findings further underscore the protective role of TLR9 in TLR7-driven autoimmunity and also in the development of vasculopathy, further strengthening the importance of tightly manipulating TLRs in putative therapeutic strategies. This study provides a new model of accelerated lupus phenotype driven by danger-associated molecular patterns.

Effect of thermo-mechanical stress during quench on Nb3Sn cable performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linda Imbasciati et al.

2002-12-09

Several high field magnets using Nb{sub 3}Sn superconductor are under development for future particle accelerators. The high levels of stored energy in these magnets can cause high peak temperatures during a quench. The thermomechanical stress generated in the winding during the fast temperature rise can result in a permanent damage of the brittle Nb{sub 3}Sn. Although there are several studies of the critical current degradation of Nb{sub 3}Sn strands due to strain, little is known about how to apply the strain limitations to define a maximum acceptable temperature in the coils during a quench. Therefore, an experimental program was launched,more » aimed at improving the understanding of the effect of thermo-mechanical stress in coils made from brittle Nb{sub 3}Sn. A first experiment, reported here, was performed on cables. The experimental results were compared to analytical and finite element models. The next step in the experimental program will be to repeat similar measurements in small racetrack coils and later in full size magnets.« less

Nano-Al{sub 2}O{sub 3} multilayer film deposition on cotton fabrics by layer-by-layer deposition method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ugur, Sule S., E-mail: sule@mmf.sdu.edu.tr; Sariisik, Merih; Aktas, A. Hakan

Highlights: {yields} Cationic charges were created on the cotton fibre surfaces with 2,3-epoxypropyltrimethylammonium chloride. {yields} Al{sub 2}O{sub 3} nanoparticles were deposited on the cotton fabrics by layer-by-layer deposition. {yields} The fabrics deposited with the Al{sub 2}O{sub 3} nanoparticles exhibit better UV-protection and significant flame retardancy properties. {yields} The mechanical properties were improved after surface film deposition. -- Abstract: Al{sub 2}O{sub 3} nanoparticles were used for fabrication of multilayer nanocomposite film deposition on cationic cotton fabrics by electrostatic self-assembly to improve the mechanical, UV-protection and flame retardancy properties of cotton fabrics. Cotton fabric surface was modified with a chemical reaction tomore » build-up cationic charge known as cationization. Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy, X-ray Photoelectron Spectroscopy and Scanning Electron Microscopy were used to verify the presence of deposited nanolayers. Air permeability, whiteness value, tensile strength, UV-transmittance and Limited Oxygen Index properties of cotton fabrics were analyzed before and after the treatment of Al{sub 2}O{sub 3} nanoparticles by electrostatic self-assemblies. It was proved that the flame retardancy, tensile strength and UV-transmittance of cotton fabrics can be improved by Al{sub 2}O{sub 3} nanoparticle additive through electrostatic self-assembly process.« less

Evaluation of positive G sub Z tolerance following simulated weightlessness (bedrest)

NASA Technical Reports Server (NTRS)

Jacobson, L. B.; Hyatt, K. H.; Sullivan, R. W.; Cantor, S. A.; Sandler, H.; Rositano, S. A.; Mancini, R. E.

1973-01-01

The magnitude of physiologic changes which are known to occur in human subjects exposed to varying levels of + G sub Z acceleration following bed rest simulation of weightlessness was studied. Bed rest effects were documented by fluid and electrolyte balance studies, maximal exercise capability, 70 deg passive tilt and lower body negative pressure tests and the ability to endure randomly prescribed acceleration profiles of +2G sub Z, +3G sub Z, and +4G sub Z. Six healthy male volunteers were studied during two weeks of bed rest after adequate control observations, followed by two weeks of recovery, followed by a second two-week period of bed rest at which time an Air Force cutaway anti-G suit was used to determine its effectiveness as a countermeasure for observed cardiovascular changes during acceleration. Results showed uniform and significant changes in all measured parameters as a consequence of bed rest including a reduced ability to tolerate +G sub Z acceleration. The use of anti-G suits significantly improved subject tolerance to all G exposures and returned measured parameters such as heart rate and blood pressure towards or to pre-bed-rest (control) values in four of the six cases.

Energetic metallic ion implantation in polymers via cost-effective laser-driven ion source

NASA Astrophysics Data System (ADS)

Tahir, Muhammad Bilal; Rafique, M. Shahid; Ahmed, Rabia; Rafique, M.; Iqbal, Tahir; Hasan, Ali

2017-07-01

This research work reports the ions emission from the plasma generated by Nd:YAG laser having wavelength 1.064 μm, power 1.1 MW, pulse energy 10 mJ and intensity 1011 W/cm2 irradiated at 70° with respect to the target normal to the ions. These ions were accelerated through a home-made extraction assembly by means of a high voltage DC power supply. The energy of these ions were measured using Thomson parabola technique which utilizes Solid State Nuclear Track Detector (CR-39) and confirmed by Faraday cup as well that exploits a well-known technique known as time of flight. Interestingly, a significant increase in energy (from 490 to 730 keV) was observed with a discrete increase in acceleration potential from 0 to 18 kV. Polyethylene terephthalate (PET) and polypropylene were exposed to this recently developed ion source facility, to authenticate the reliability of this facility. The surface of the polymer is affected when energy of the irradiated ion is increased, which is evident from the optical micrographs. An increase in electrical conductivity was also observed with the increase in ion energy.

Direct-write assembly of microperiodic planar and spanning ITO microelectrodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahn, Bok Y; Lorang, David J; Duoss, Eric B.

2010-01-01

Printed Sn-doped In{sub 2}O{sub 3} (ITO) microelectrodes are fabricated by direct-write assembly of sol–gel inks with varying concentration. This maskless, non-lithographic approach provides a facile route to patterning transparent conductive features in planar arrays and spanning architectures.