Science.gov

Sample records for accomplishments identifying challenges

  1. Space Biophysics: Accomplishments, Trends, Challenges

    NASA Technical Reports Server (NTRS)

    Smith, Jeffrey D.

    2015-01-01

    the protective environment of Earth, the biophysical properties underlying these changes must be studied, characterized and understood. This lecture reviews the current state of NASA biophysics research accomplishments and identifies future trends and challenges for biophysics research on the International Space Station and beyond.

  2. Unraveling bovin phylogeny: accomplishments and challenges.

    PubMed

    Bibi, Faysal; Vrba, Elisabeth S

    2010-01-01

    The phylogenetic systematics of bovin species forms a common basis for studies at multiple scales, from the level of domestication in populations to major cladogenesis. The main big-picture accomplishments of this productive field, including two recent works, one in BMC Genomics, are reviewed with an eye for some of the limitations and challenges impeding progress. PMID:20525112

  3. Unraveling bovin phylogeny: accomplishments and challenges

    PubMed Central

    2010-01-01

    The phylogenetic systematics of bovin species forms a common basis for studies at multiple scales, from the level of domestication in populations to major cladogenesis. The main big-picture accomplishments of this productive field, including two recent works, one in BMC Genomics, are reviewed with an eye for some of the limitations and challenges impeding progress. See Research article http://www.biomedcentral.com/1471-2164/10/177 PMID:20525112

  4. Assessing Accomplished Teaching: Good Strides, Great Challenges

    ERIC Educational Resources Information Center

    Norman, Antony D.

    2010-01-01

    This article surveys efforts at the national and international level to define and assess accomplished teaching with particular attention devoted to how assessments of accomplished teaching connect to student learning. The author finds that most assessments are based on aspects of teaching that, presumably, come together as accomplished teaching.…

  5. Reclaiming our roots: accomplishments and challenges.

    PubMed

    King, Janet

    2011-01-01

    Best practices for Native Americans are rooted in culture. However, reclaiming best practices is a challenge given the genocidal policies that outlawed Native culture. Despite this challenge Native people have proven resilient in restoring culture. The Native American Health Center in Oakland, California, has made cultural interventions an option for an urban, intertribal and sometimes multiracial Native American population to create and maintain their health on a spiritual, emotional, mental and physical level. Nevertheless, sustaining these cultural options to maintain health continues to be a challenge. While the passage of the Mental Health Services Act (MHSA) in 2004 in California to transform treatment of mental and behavioral health "as we know it" would seem to create a gateway for cultural options, mainstream mental health has a hard time perceiving cultural interventions as a viable means to treat mental illness and maintain wellness. Frequently, the author has attended meetings of decisionmaking bodies that oversee how MHSA money is spent and someone will blurt out after someone has described an innovative cultural intervention "What does that have to do with mental illness?" The following article discusses how the clash of the two cultures, Native and mainstream, continues to be a challenge for sustained funding to implement culturally competent programs. PMID:22400460

  6. APPLYING SIMPLE TECHNOLOGY ACCOMPLISHES VISUAL INSPECTION CHALLENGES

    SciTech Connect

    Robinson, C

    2007-07-21

    This paper discusses the successful implementation of simple video technologies at the Savannah River Site (SRS) to perform complex visual inspection, monitoring, and surveillance tasks. Because SRS facilities are similar to those of an industrial plant, the environmental and accessibility considerations for remote viewing are the primary determining factors in the selection of technology. The constraints and challenges associated with remote viewing are discussed, and examples of applications are given.

  7. Accomplishing Transformative Research in a Challenging Fiscal Environment

    NASA Astrophysics Data System (ADS)

    Mitchell, E. J.; Paxton, L. J.; Bust, G.

    2014-12-01

    The shift in funding is forcing scientists to promise transformative research for a pittance. To accomplish this, researchers need to transform their methodology to include societal buy-in, use of commercial off-the-shelf (COTS) technology, and cross-discipline platform usage. As the cutting edge of research expands to view the system on the global scale with extremely fine resolution, fiscally reasonable budgets present a challenge to be met. Consider how do we measure a specific variable over 45-degrees of latitude in an isolated and hostile region of Earth - the total electron count over the South Pole? This work examines this transformative research using hosted payloads on buoys, balloons, and unmanned aerial vehicles (UAVs). We will show cutting edge research occurring simultaneous with education and public outreach, offering societal buy-in through interactive websites and student-built hosted payloads. These interactions provide a vision to the public and a new database to the scientists. The use of COTS technology and cross-discipline (oceanography and space) platforms keep the cost low. We will discuss a general methodology for accomplishing transformative research in a challenging fiscal environment through integration of COTS technology, assimilative and first principle models, and observing systems simulation experiments (OSSEs).

  8. Children's Health Insurance Program (CHIP): accomplishments, challenges, and policy recommendations.

    PubMed

    Racine, Andrew D; Long, Thomas F; Helm, Mark E; Hudak, Mark; Racine, Andrew D; Shenkin, Budd N; Snider, Iris Grace; White, Patience Haydock; Droge, Molly; Harbaugh, Norman

    2014-03-01

    Sixteen years ago, the 105th Congress, responding to the needs of 10 million children in the United States who lacked health insurance, created the State Children's Health Insurance Program (SCHIP) as part of the Balanced Budget Act of 1997. Enacted as Title XXI of the Social Security Act, the Children's Health Insurance Program (CHIP; or SCHIP as it has been known at some points) provided states with federal assistance to create programs specifically designed for children from families with incomes that exceeded Medicaid thresholds but that were insufficient to enable them to afford private health insurance. Congress provided $40 billion in block grants over 10 years for states to expand their existing Medicaid programs to cover the intended populations, to erect new stand-alone SCHIP programs for these children, or to effect some combination of both options. Congress reauthorized CHIP once in 2009 under the Children's Health Insurance Program Reauthorization Act and extended its life further within provisions of the Patient Protection and Affordable Care Act of 2010. The purpose of this statement is to review the features of CHIP as it has evolved over the 16 years of its existence; to summarize what is known about the effects that the program has had on coverage, access, health status, and disparities among participants; to identify challenges that remain with respect to insuring this group of vulnerable children, including the impact that provisions of the new Affordable Care Act will have on the issue of health insurance coverage for near-poor children after 2015; and to offer recommendations on how to expand and strengthen the national commitment to provide health insurance to all children regardless of means. PMID:24470647

  9. Global sea level record from satellite altimetry: accomplishments and challenges

    NASA Astrophysics Data System (ADS)

    Fu, L.

    2013-12-01

    The trend of sea level change and its geographic pattern present a powerful indicator of the overall extent of climate change as well as pose a long-term threat to the world's heavily populated coastal zones. The global and direct measurement of sea level from satellite altimetry over the past two decades, as a key part of a global observing system, has enabled quantitative determination of sea level change and its relation to natural and human-induced causes. Major results from the data record will be reviewed to highlight the challenges in distinguishing between natural variability and long-term trends from human activities. As long-term climate data records from satellite observations are inevitably to be built from successive missions with progressively changing technologies, a major challenge is concerted effort in cross-calibration to ensure consistency between new measurements with existing records. As the desire of increasing spatial resolution to resolve energetic small-scale variability dictates the development of high-resolution wide-swath altimeter, the need for thoughtful design of a system that is able to demonstrate proper transition of technologies in terms of providing consistent global sea level data record will be discussed.

  10. IAIMS at Columbia-Presbyterian Medical Center: accomplishments and challenges.

    PubMed Central

    Roderer, N K; Clayton, P D

    1992-01-01

    The concept of "one-stop information shopping" is becoming a reality at Columbia-Presbyterian Medical Center. Our goal is to provide access from a single workstation to clinical, research, and library resources; university and hospital administrative systems; and utility functions such as word processing and mail. We have created new organizational units and installed a network of workstations that can access a variety of resources and systems on any of seventy-two different host computers/servers. In November 1991, 2,600 different individuals used the clinical information system, 700 different individuals used the library resources, and 900 different individuals used hospital administrative systems via the network. Over the past four years, our efforts have cost the equivalent of $23 million or approximately 0.5% of the total medical center budget. Even small improvements in productivity and in the quality of work of individuals who use the system could justify these expenditures. The challenges we still face include the provision of additional easy-to-use applications and development of equitable methods for financial support. PMID:1326368

  11. Florida's Adult Education Programs: Challenges and Accomplishments. A Report for Fiscal Year 1991 [and] Fiscal Year 1992.

    ERIC Educational Resources Information Center

    Gardner, Daniel L.

    These two reports outline accomplishments and challenges faced by Florida's AE program in FY91 and FY92 in the following areas: adult literacy, social participation, career development, special needs of the AE program's diverse identified target groups, high school completion, General Educational Development, workplace literacy, networking,…

  12. Status of selected ion flow tube MS: accomplishments and challenges in breath analysis and other areas.

    PubMed

    Smith, David; Španěl, Patrik

    2016-06-01

    This article reflects our observations of recent accomplishments made using selected ion flow tube MS (SIFT-MS). Only brief descriptions are given of SIFT-MS as an analytical method and of the recent extensions to the underpinning analytical ion chemistry required to realize more robust analyses. The challenge of breath analysis is given special attention because, when achieved, it renders analysis of other air media relatively straightforward. Brief overviews are given of recent SIFT-MS breath analyses by leading research groups, noting the desirability of detection and quantification of single volatile biomarkers rather than reliance on statistical analyses, if breath analysis is to be accepted into clinical practice. A 'strengths, weaknesses, opportunities and threats' analysis of SIFT-MS is made, which should help to increase its utility for trace gas analysis. PMID:27212131

  13. US CLIVAR Accomplishments Over the Past 15 Years and Research Challenges for the Future

    NASA Astrophysics Data System (ADS)

    Uhlenbrock, K.; Patterson, M. W.

    2014-12-01

    The US Climate Variability and Predictability Program (CLIVAR) has brought meaningful contributions to the understanding of the role the ocean plays in the global climate system since its launch in 1998. By fostering community-based planning and implementation, US CLIVAR has made strides in increasing our understanding of the climate system and its predictability. Key accomplishments include a better understanding of intraseasonal-to-centennial timescales, expansion of a sustained ocean observing system for monitoring and assessing climate variability and change, improved understanding of critical physical processes and their representation in climate and Earth system models, and coordinated inter-comparisons of ocean and coupled simulations that have led to improved predictive capability. Building upon these advancements, the new US CLIVAR Science Plan presents revised goals, strategies, and research challenges that emphasize strengthened ties to the broader Earth science community and relevance to societal impacts. We will highlight the scope and priorities for each of the following four research challenges: (i) decadal variability and predictability; (ii) climate and extreme events; (iii) polar climate; and (iv) climate and ocean biogeochemistry. We will also provide information on how scientists can participate in future planning and implementation activities.

  14. HIV prevention research: accomplishments and challenges for the third decade of AIDS.

    PubMed Central

    Auerbach, J D; Coates, T J

    2000-01-01

    The past 2 decades have taught us that HIV prevention can work. We now have evidence from places as diverse as Senegal, Thailand, Uganda, and Australia that concerted HIV prevention efforts at the national level have resulted in the maintenance of low seroprevalence rates where they otherwise would have been expected to rise. We are beginning to observe declining rates of HIV prevalence and incidence in places and populations with historically high rates--for example, injection drug users in New York City. This trend points to the long-term impact of prevention efforts in those communities. The best of these efforts have been based on sound scientific research. As we move into the third decade of the AIDS epidemic, it is important to restate principles, acknowledge advances, and identify challenges and future directions in HIV prevention research. PMID:10897177

  15. Service Efforts and Accomplishments (SEA) Reporting: A Challenge for School Financial Reporting.

    ERIC Educational Resources Information Center

    Walter, Donald L.

    1991-01-01

    Discusses the Government Accounting Standards Board (GASB) research concerning the identification of indicators of service efforts and service accomplishments. The GASB has proposed that financial reports should not only be useful in assessing accountability, but they should also assist in making economic, social, and political decisions. (six…

  16. Measurement in Physical Education and Exercise Science (MPEES): Accomplishments and Challenges

    ERIC Educational Resources Information Center

    Liu, Yuanlong

    2007-01-01

    This year marks the 10th year of publication for "Measurement in Physical Education and Exercise Science" (MPEES). As we are forging into future, it would be very helpful to evaluate the role MPEES has played in the evolution of the research in physical education and exercise science. In this issue, the authors address the challenges that MPEES…

  17. International Year of Planet Earth - Accomplishments, Activities, Challenges and Plans in Mexico

    NASA Astrophysics Data System (ADS)

    Fucugauchi, J. U.; Perez-Cruz, L. L.; Alaniz-Alvarez, S.

    2009-12-01

    The International Year of Planet Earth started as a joint initiative by UNESCO and IUGS with the participation of several geosciences organizations, and developed into a major international geosciences program for the triennium 2007-2009, with the inclusion and participation of national and regional committees. In this presentation we focus on current activities and plans in our country and the participation in international activities. Mexican community has been part of international programs since the International Geophysical Year, continuing through its participation in other programs, e.g., Upper Mantle, Geodynamics, Lithosphere, IHY, IPY and eGY. IYPE activities have concentrated in publications, OneGeology, radio/TV programs, organization of conferences, meetings and outreach events. A book series on Earth Science Experiments for Children has been edited, with first books published on “Atmospheric Pressure and Free Fall of Objects”, “Light and Colors”, “Standing on Archimedes”, “Foucault and Climate” and “Earth and its Waves “. Books are distributed to schools, with tens of thousand copies distributed nationwide and new editions underway. Other publications include leaflets, books and special El Faro issues (edited by the National University) and articles in other journals. In 2007 the AGU Joint Assembly with international participation from US, Canada, Europe and Latin America was held in Acapulco. Current plans include an electronic open-access journal, additional publications of the Planet Earth series, articles and special issues in journals and magazines, plus events on selected themes from the IYPE science program, particularly on Megacities, Hazards, Resources and Biodiversity. Mexico City metropolitan area, with > 22 million inhabitants presents special challenges, being at high altitude within an active tectonic and volcanic area requiring major efforts in water supply, water control, rains and waste disposal and management

  18. Progress in the Exploration of Thermosphere / Ionosphere Coupling: Accomplishments, Frontiers and Challenges

    NASA Astrophysics Data System (ADS)

    Paxton, L. J.

    2012-12-01

    In this paper we review some of the things that we have learned about the response of the thermosphere and ionosphere during disturbed and undisturbed conditions. We will provide a very brief overview of what the far ultraviolet measurements (such as those from GUVI and SSUSI) mean and how the data and data products can be accessed. The goal of that overview is to generate future collaborative activities. We will show: 1) the results of our work on the evolution of thermospheric "storm fronts" as imaged in changes in composition (the O/N2 ratio) and how that response varies with longitude, hemisphere and solar cycle 2) the large scale structure of the nightside F-region ionosphere and the variation with longitude 3) the distribution of ionospheric bubbles and what we can learn from the tomographic inversion of those bubbles. As powerful as UV remote sensing from low Earth orbit (it is only from LEO that we can perform tomographic reconstruction of the 3D structure of bubbles from a single platform), there are many other important measurements that can help address how the system is coupled. This talk will introduce a few of those problems. We will highlight some of the data sources we'd like to develop and the tools and partnerships we'd like to see enhanced and the challenges that face our community in the next few years - especially in the context of the Decadal Survey report.

  19. Identifying Challenges in Supervising School Psychologists

    ERIC Educational Resources Information Center

    Harvey, Virginia Smith; Pearrow, Melissa

    2010-01-01

    Previous studies suggest that the majority of school psychologists do not believe they receive sufficient supervision, despite a growing body of research providing empirical support for supervision to maintain and improve skills. This study explores the dynamics underlying the challenges of providing adequate supervision to school psychologists.…

  20. Accomplishments '70.

    ERIC Educational Resources Information Center

    Stanford Univ., CA. Stanford Center for Research and Development in Teaching.

    This annual report examines the accomplishments during 1970 of three programs. The first program was to improve the organizational and administrative environment for teaching. Its subsidiary projects were 1) the organizational context of teaching; 2) professional socialization of the teacher; 3) attitudes of teachers toward their occupation; 4)…

  1. Replacement Behaviors for Identified Functions of Challenging Behaviors

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Shoemaker, Mary E.; Sipes, Megan; Horovitz, Max; Worley, Julie A.; Kozlowski, Alison M.

    2011-01-01

    Functional assessment has become a major feature of learning-based research. A critical element of the majority of these studies includes not only methods and procedures to identify the cause of the challenging behavior, but to establish replacement treatment methods. By far the most common intervention in the 176 studies we reviewed was…

  2. Program Accomplishments

    SciTech Connect

    none,

    2011-10-01

    The U.S. Department of Energy's (DOE's) efforts have greatly advanced the state of the art of hydrogen and fuel cell technologies—making significant progress toward overcoming many of the key challenges to widespread commercialization. DOE has also made major advances by demonstrating and validating the technologies under real-world conditions, supporting early markets through Recovery Act deployments, and leveraging domestic and international partnerships to advance the pace of commercialization.

  3. Challenging Out-of-School Activities as a Predictor of Creative Accomplishments in Art, Drama, Dance, and Social Leadership.

    ERIC Educational Resources Information Center

    Milgram, Roberta M.

    2003-01-01

    Studied the relationship between performance of challenging out-of-school activities and real-world talent in art, drama, social leadership, and dance in four separate studies of high school students (total n=222) in grades 9 through 12. The strong relationship between predictor and criterion in each of the four domains demonstrated the concurrent…

  4. Contributions of pesticide residue chemistry to improving food and environmental safety: past and present accomplishments and future challenges.

    PubMed

    Seiber, James N; Kleinschmidt, Loreen A

    2011-07-27

    The principles of modern pesticide residue chemistry were articulated in the 1950s. Early authors pointed out the advantages of systematizing and standardizing analytical methods for pesticides so that they could be widely practiced and the results could be reproduced from one laboratory to the next. The availability of improved methods has led to a much more complete understanding of pesticide behavior and fate in foods and the environment. Using methods based largely upon gas chromatography (GC) and high-performance liquid chromatography (HPLC) coupled increasingly with mass spectrometry (MS) and MS(n) as the detection tool, residues can be measured at parts per billion levels and below in a variety of food and environmental matrices. Development of efficient extraction and cleanup methods, techniques such as ELISA, efficient sample preparation techniques such as QuEChERS, and automated laboratory and field instrumentation has also contributed to the tools available for use in modern pesticide residue analysis. As a result, great strides have been made in improving food and worker safety and in understanding environmental behavior and fate of pesticides. There are many challenges remaining in the field of pesticide residue chemistry that will continue to stimulate analytical chemists. New chemistries are emerging, often patterned on complex natural products. Analyzing for the parent chemicals and potentially multiple breakdown products will require analytical ingenuity. The development of more sensitive bioassays and knowledge of unintended side effects will challenge residue chemistry as well, as in the case of following the fate of environmental endocrine disruptors associated with some pesticides as well as nonpesticide contaminants from packaging materials and other familiar articles. Continued funding and other resources to ensure better training, international cooperation, and accelerated research and development activities will be a constant need in

  5. From single-gene to multiplex analysis in lung cancer, challenges and accomplishments: a review of a single institution's experience

    PubMed Central

    Zhao, Weiqiang; Damodaran, Senthilkumar; Villalona-Calero, Miguel A

    2014-01-01

    SUMMARY Molecular selection has led to the successful use of novel tyrosine kinase inhibitors (TKIs) in non-small-cell lung cancers (NSCLCs). For instance, mutations in EGFR and translocations and fusions in ALK render tumor cells sensitive to some TKIs, leading to substantial clinical benefits. Molecular testing such as DNA sequencing or fragment analysis following PCR, and evaluation of copy number and gene positioning by FISH, have been developed and used clinically to identify mutations/fusions. Meanwhile, TKIs to target actionable mutations/fusions in several other oncogenes are being evaluated. High-throughput sequencing can provide therapy-predictive information as well as identify novel targetable genomic alterations. In this article, we report our experience enabling single-gene testing, and our evolution to panel-based next-generation sequencing. PMID:25580159

  6. The challenge of identifying greenhouse gas-induced climatic change

    NASA Technical Reports Server (NTRS)

    Maccracken, Michael C.

    1992-01-01

    Meeting the challenge of identifying greenhouse gas-induced climatic change involves three steps. First, observations of critical variables must be assembled, evaluated, and analyzed to determine that there has been a statistically significant change. Second, reliable theoretical (model) calculations must be conducted to provide a definitive set of changes for which to search. Third, a quantitative and statistically significant association must be made between the projected and observed changes to exclude the possibility that the changes are due to natural variability or other factors. This paper provides a qualitative overview of scientific progress in successfully fulfilling these three steps.

  7. Performance as Promised: How the Chandra X-ray Observatory Accomplished One of Nasa's Most Challenging Missions for Billions of Dollars Less than Originally Planned

    NASA Technical Reports Server (NTRS)

    Davidson, Greg; Hefner, Keith

    2004-01-01

    As the nation looks toward bold new ventures in space, the Chandra X-ray Observatory program offers an example of how billion-dollar missions can be successfully developed within tightening fiscal constraints. Chandra experienced many of challenges facing bold space programs (state-of-the-art technical requirements and budget-induced slips and restructurings), and yet the Chandra team achieved nearly all the originally envisioned performance for dramatically lower cost. This was accomplished by a combination of team- work, systems engineering, advanced technology insertion, and effective approaches for program implementation. A thorough tradeoff of science utility vs. cost led to the selection of a highly elliptical orbit with uncrewed robotic delivery, deployment, and maintenance. Progressive, focused technology demonstrations were accomplished prior to commitment of major resources to critical elements of the system design, such as the high resolution mirror assembly (HRMA). Pathfinder hardware was developed to reduce risks. A variety of schedule risk reduction measures were implemented and resulted in the X-ray calibration taking place exactly within five days of its originally planned date after after five years of development. The team worked together in an effective manner to contain requirements creep. reductions such as the ACIS-2 chip device. It is estimated that the above combination of measures achieved the avoidance of over $4B in costs, while enabling a highly successful mission.

  8. Making It Work: Identifying the Challenges of Collaborative International Research

    ERIC Educational Resources Information Center

    Goddard, Tim; Cranston, Neil; Billot, Jennie

    2006-01-01

    In this article, we explore the challenges--and benefits--of conducting collaborative research on an international scale. The authors--from Australia, Canada, and New Zealand--draw upon their experiences in designing and conducting a three-country study. The growing pressures on scholars to work in collaborative research teams are described, and…

  9. Identifying and Addressing Challenges to Research in University Laboratory Preschools

    ERIC Educational Resources Information Center

    File, Nancy

    2012-01-01

    Research Findings: This essay offers a review of challenges that university laboratory preschools face in providing a site for research that fits with other components of the program mission. An argument is made to consider paradigm shifts in research questions and methods that move away from traditions within the fields that study children's…

  10. Identifying challenges for academic leadership in medical universities in Iran.

    PubMed

    Bikmoradi, Ali; Brommels, Mats; Shoghli, Alireza; Khorasani-Zavareh, Davoud; Masiello, Italo

    2010-05-01

    CONTEXT The crucial role of academic leadership in the success of higher education institutions is well documented. Medical education in Iran has been integrated into the health care system through a complex organisational change. This has called into question the current academic leadership, making Iranian medical universities and schools a good case for exploring the challenges of academic leadership. OBJECTIVES This study explores the leadership challenges perceived by academic managers in medical schools and universities in Iran. METHODS A qualitative study using 18 face-to-face, in-depth interviews with academic managers in medical universities and at the Ministry of Health and Medical Education in Iran was performed. All interviews were recorded digitally, transcribed verbatim and analysed by qualitative content analysis. RESULTS The main challenges to academic leadership could be categorised under three themes, each of which included three sub-themes: organisational issues (inefficacy of academic governance; an overly extensive set of missions and responsibilities; concerns about the selection of managers); managerial issues (management styles; mismatch between authority and responsibilities; leadership capabilities), and organisational culture (tendency towards governmental management; a boss-centred culture; low motivation). CONCLUSIONS This study emphasises the need for academic leadership development in Iranian medical schools and universities. The ability of Iranian universities to grow and thrive will depend ultimately upon the application of leadership skills. Thus, it is necessary to better designate authorities, roles of academic staff and leaders at governance. PMID:20518985

  11. Life sciences accomplishments

    NASA Technical Reports Server (NTRS)

    1985-01-01

    From its inception, the main charter of Life Sciences has been to define biomedical requirements for the design and development of spacecraft systems and to participate in NASA's scientific exploration of the universe. The role of the Life Sciences Division is to: (1) assure the health, well being and productivity of all individuals who fly in space; (2) study the origin, evolution, and distribution of life in the universe; and (3) to utilize the space environment as a tool for research in biology and medicine. The activities, programs, and accomplishments to date in the efforts to achieve these goals are detailed and the future challenges that face the division as it moves forward from the shuttle era to a permanent manned presence in space space station's are examined.

  12. The Challenge of Identifying Gifted/Learning Disabled Students

    ERIC Educational Resources Information Center

    Krochak, Linda A.; Ryan, Thomas G.

    2007-01-01

    The following contemporary review illuminates several of the "best methods" to accurately identify gifted/learning disabled (GLD) students? Explanations which clearly define what it means to be gifted, learning disabled (LD) and gifted/learning disabled (GLD) are included and incorporated into a typology of three identities of GLD students.…

  13. Identifying Quality in Preschool Education: Progress and Challenge

    ERIC Educational Resources Information Center

    Hughes, Jan N.

    2010-01-01

    In this article, the author comments on Dominguez, Vitiello, Maier, and Greenfield's (2010) article on identifying quality in preschool education. Dominguez et al. have conducted a methodologically sophisticated study describing the growth of learning behavior among Head Start children. By doing so, they contribute to a growing body of evidence…

  14. Mississippi Tech-Prep Coordinators: Identifying Challenges of the Job

    ERIC Educational Resources Information Center

    McDavid, Jean Alice; Boggs, Brad D.; Stumpf, Dan

    2005-01-01

    Mississippi tech-prep coordinators were surveyed to determine their perceptions of the difficulty of their various job responsibilities as identified in the Mississippi Tech Prep Handbook Pilot Site Implementation Guide 1993-94 (1993). It was hypothesized that their perceptions would be influenced by the number of sites served by individual…

  15. Identifying present challenges to reliable future transdermal drug delivery products.

    PubMed

    Giannos, Steven A

    2015-01-01

    Transdermal systems have become an accepted means of drug delivery, offering clinical benefits over other dosage forms. Although transdermal delivery has been very successful as a controlled release technology platform, there are a number of challenges that prevent this delivery route from achieving its fullest commercial potential. Additionally, beginning in 1997, transdermal drug delivery companies aligned with life science industries to deliver large molecules, peptides and proteins through the skin, which is difficult due to the skin barrier properties. A number of methods and technologies have been conceived to overcome the skin barrier. Among these are mechanical, chemical and thermal permeation enhancement techniques. These methods are briefly discussed as well as future directions for transdermal therapies. PMID:26419262

  16. Developing paediatric medicines: identifying the needs and recognizing the challenges.

    PubMed

    Ernest, Terry B; Elder, David P; Martini, Luigi G; Roberts, Matthew; Ford, James L

    2007-08-01

    There is a significant need for research and development into paediatric medicines. Only a small fraction of the drugs marketed and utilized as therapeutic agents in children have been clinically evaluated. The majority of marketed drugs are either not labelled, or inadequately labelled, for use in paediatric patients. The absence of suitable medicines or critical safety and efficacy information poses significant risks to a particularly vulnerable patient population. However, there are many challenges associated with developing medicines for the paediatric population and this review paper is intended to highlight these. The paediatric population is made up of a wide range of individuals of substantially varied physical size, weight and stage of physiological development. Experimentation on children is considered by many to be unethical, resulting in difficulties in obtaining critical safety data. Clinical trials are subject to detailed scrutiny by the various regulatory bodies who have recently recognized the need for pharmaceutical companies to invest in paediatric medicines. The costs associated with paediatric product development could result in poor or negative return on investment and so incentives have been proposed by the EU and US regulatory bodies. Additionally, some commonly used excipients may be unsuitable for use in children; and some dosage forms may be undesirable to the paediatric population. PMID:17725846

  17. Wind Program Accomplishments

    SciTech Connect

    Wind Program

    2012-05-24

    This fact sheet describes some of the accomplishments of DOE's Wind Program through its investments in technology development and market barrier reduction, and how those accomplishments are supporting the advancement of renewable energy generated using the United States' abundant wind resources.

  18. The Spacelab Accomplishments Forum

    NASA Technical Reports Server (NTRS)

    Emond, J. (Editor); Bennett, N. (Compiler); McCauley, D. (Compiler); Murphy, K. (Compiler)

    2000-01-01

    This document is a record of the Spacelab Accomplishments Forum held in March 1999. Presentations made at the Forum covered the design, engineering, utilization, and science associated with Spacelab, as well as the international associations and impact of Spacelab and its use in the design and utilization of the International Space Station. Topics included Earth observations, space science, life science, commercial uses, microgravity science, and international participation.

  19. Identifying the Ethical Challenges Encountered by Information Technology Professionals Working within the Nevada Casino Industry

    ERIC Educational Resources Information Center

    Essig, Michael R.

    2014-01-01

    A thematic analysis qualitative study was used to identify the unethical challenges encountered by Information Technology (IT) professionals working within the Nevada casino industry. Fourteen current and former IT leaders working or who worked in the Nevada casino industry were interviewed. Using thematic analysis, nine themes regarding ethical…

  20. Identifying the Challenging Factors in the Transition from Colleges of Engineering to Employment

    ERIC Educational Resources Information Center

    Baytiyeh, Hoda; Naja, Mohamad

    2012-01-01

    The transition from university to a career in engineering is a challenging process. This study examined the perceptions of engineering graduates regarding the difficulties they encountered in their transition from the university to the workplace. Lebanese practising engineers (n=217), living around the world, were surveyed to identify their…

  1. Preoperative psychological assessment of patients seeking weight-loss surgery: identifying challenges and solutions

    PubMed Central

    Edwards-Hampton, Shenelle A; Wedin, Sharlene

    2015-01-01

    Preoperative psychosocial assessment is the standard of care for patients seeking weight-loss surgery (WLS). However, the assessment procedure varies widely by surgery site. Comprehensive assessments can provide a wealth of information that assists both the patient and the treatment team, anticipate and prepare for challenges associated with extensive behavioral and lifestyle changes that are required postsurgery. In this review, we provide an overview of the purpose of the preoperative psychosocial assessment and domains to be included. Challenges commonly identified in the assessment are discussed, including maladaptive eating behaviors, psychiatric comorbidities, and alcohol use. Potential solutions and approaches to these challenges are provided. Additionally, patient populations requiring special consideration are presented to include adolescents, those with cognitive vulnerabilities, and aging adults. PMID:26604844

  2. Identifying the challenging factors in the transition from colleges of engineering to employment

    NASA Astrophysics Data System (ADS)

    Baytiyeh, Hoda; Naja, Mohamad

    2012-03-01

    The transition from university to a career in engineering is a challenging process. This study examined the perceptions of engineering graduates regarding the difficulties they encountered in their transition from the university to the workplace. Lebanese practising engineers (n=217), living around the world, were surveyed to identify their current employment situations and their attitudes toward their academic preparation. Factor analysis revealed three main challenges facing engineering graduates: communication; responsibility; self-confidence. Seventeen interviews were conducted to gather information on ways to facilitate this transition. Comments reflected the need for better collaboration between engineering schools and engineering firms. The results will provide insight for engineering colleges, faculty members and administrators into the challenges faced by graduates and their aspirations for a smoother transition into employment.

  3. 2000 FEMP Accomplishments Report

    SciTech Connect

    2001-02-01

    The Federal Government can set extraordinary examples for the American public by its leadership on energy and the environment. In this first year of the new millenium, we have proven that, through our strong Federal partnerships, we can take on and meet impressive challenges to reduce energy use and cost.

  4. Accomplished Urban Teaching

    ERIC Educational Resources Information Center

    Abbate-Vaughn, Jorgelina; Frechon, Olga; Wright, Brian L.

    2010-01-01

    This article discusses the relevance of four dimensions of urban teaching: foci on relationships and shared authority, linking classroom content with student experience, incorporation of familiar and culturally compatible communication patterns, and development of counter narratives that challenge stereotypical conceptions of at-risk students and…

  5. Life Sciences Accomplishments 1994

    NASA Technical Reports Server (NTRS)

    Burnell, Mary Lou (Editor)

    1993-01-01

    proposals for ground-based and flight research for all programs. Areas of particular interest to NASA were defined Proposals due April 29, 1994, will be peer reviewed - externally for scientific merit. This annual NRA process is now the mechanism for recruiting both extramural and intramural investigations. As an overview of LBSAD activities in 1993, this accomplishments document covers each of the major organizational components of the Division and the accomplishments of each. The second section is a review of the Space Life Sciences Research programs Space Biology, Space Physiology and Countermeasures, Radiation Health, Environmental Health, Space Human Factors, Advanced Life Support, and Global Monitoring and Disease Prediction, The third section, Research in Space Flight, describes the substantial contributions of the Spacelab Life Sciences 2 (SLS-2) mission to life sciences research and the significant contributions of the other missions flown in 1993, along with plans for future missions. The Division has greatly expanded and given high priority to its Education and Outreach Programs, which are presented in the fourth section. The fifth and final section, Partners for Space, shows the Divisions Cooperative efforts with other national and international agencies to achieve common goals, along with the accomplishments of joint research and analysis programs.

  6. EFRC CMSNF Major Accomplishments

    SciTech Connect

    D. Hurley; Todd R. Allen

    2014-09-01

    The mission of the Center for Material Science of Nuclear Fuels (CMSNF) has been to develop a first-principles-based understanding of thermal transport in the most widely used nuclear fuel, UO2, in the presence of defect microstructure associated with radiation environments. The overarching goal within this mission was to develop an experimentally validated multiscale modeling capability directed toward a predictive understanding of the impact of radiation and fission-product induced defects and microstructure on thermal transport in nuclear fuel. Implementation of the mission was accomplished by integrating the physics of thermal transport in crystalline solids with microstructure science under irradiation through multi institutional experimental and computational materials theory teams from Idaho National Laboratory, Oak Ridge National Laboratory, Purdue University, the University of Florida, the University of Wisconsin, and the Colorado School of Mines. The Center’s research focused on five major areas: (i) The fundamental aspects of anharmonicity in UO2 crystals and its impact on thermal transport; (ii) The effects of radiation microstructure on thermal transport in UO2; (iii) The mechanisms of defect clustering in UO2 under irradiation; (iv) The effect of temperature and oxygen environment on the stoichiometry of UO2; and (v) The mechanisms of growth of dislocation loops and voids under irradiation. The Center has made important progress in each of these areas, as summarized below.

  7. THE FUKUSHIMA RADIOLOGICAL EMERGENCY AND CHALLENGES IDENTIFIED FOR FUTURE PUBLIC HEALTH RESPONSES

    PubMed Central

    Miller, Charles W.

    2015-01-01

    On 11 March 2011, northern Japan was rocked by first a magnitude 9.0 earthquake off the eastern coast and then an ensuing tsunami. The Fukushima Daiichi Nuclear Power Plant complex was hit by these twin disasters, and a cascade of events was initiated that led to radionuclide releases causing widespread radioactive contamination of residential areas, agricultural land, and coastal waters. Radioactive material from Japan was subsequently transmitted to locations around the globe, including the U.S. The levels of radioactive material that arrived in the U.S. were never large enough to be a concern for health effects, but the presence of this material in the environment was enough to create a public health emergency in the U.S. The radiation safety and public health communities in the U.S. are identifying challenges they faced in responding to this incident. This paper discusses three of those challenges: (1) The growing shortage of trained radiation subject matter experts in the field of environmental transport and dosimetry of radionuclides; (2) the need to begin expressing all radiation-related quantities in terms of the International System of Units; and (3) the need to define when a radiation dose is or is not one of “public health concern.” This list represents only a small subset of the list of challenges being identified by public health agencies that responded to the Fukushima incident. However, these three challenges are fundamental to any radiological emergency response. Addressing them will have a significant positive impact on how the U.S. responds to the next radiological emergency. PMID:22469934

  8. The Sports Challenge international programme for identified 'at risk' children and adolescents: a Singapore study.

    PubMed

    Tester, G J; Watkins, G G; Rouse, I

    1999-01-01

    The current world wide phenomena of youth suicide which became a major issue for countries in the early nineties, is still growing exponentially. The Sports Challenge program was initiated in 1992 in Western Australia to identify 'at risk' children and adolescents who display: a low sense of basic trust, a sense of shame and doubt, a sense of inferiority and a sense of identity confusion with common characteristics of low self esteem. The subsequent program is based on a strong statistical paradigm encompassing current and historical information with reliable and objective evaluation measures. To this end, since 1992, Sports Challenge has been recognised as a 'World Best Practice' in redressing the issue of 'at risk' children and adolescents. The program now operates in over 150 schools and communities throughout Australia and 24 schools and Detention Centres in Singapore. This paper will allow a window into the development of the program and the successful transfer of the project into Singapore. The Singapore study which began in 1996 has revealed the success of the Sports Challenge program cross culturally with improvement in self esteem and self concept of 'at risk' groups in the range of 18% to 44%. PMID:10829826

  9. Hipparcos: mission accomplished

    NASA Astrophysics Data System (ADS)

    1993-08-01

    satellite. These catalogues will be of enormous value in astronomers' attempts to understand and describe the properties and evolution of stars, and the dynamical motion of these stars within our Galaxy. In the process, HIPPARCOS has discovered many thousands of new binary star systems, measured the precise light variations of many hundreds of thousands of stars over its operational lifetime, and has provided an accurate and independent validation of the predictions of General Relativity. Scientists working with ESA on the HIPPARCOS programme, were at ESOC on 13-14 July to review the progress of the data processing, and to examine whether any further efforts might allow the satellite to continue operating. "All of us are sorry to see the end of this remarkable satellite" said Dr. Michael Perryman, ESA scientist responsible for HIPPARCOS, "On the other end, we are delighted that it has delivered substantially more than it had been originally designed for. When our final results are published, some very interesting new insights into the nature of our Galaxy, its structure and its evolution, will emerge" he added. A large team of scientists from the various ESA member states are responsible for the analysis and interpretation of the vast amount of data that has been generated by the HIPPARCOS satellite, in what is considered to be the largest single data processing challenge ever undertaken in astronomy. Working with ESA since the time of the mission acceptance in 1980, their immediate work will only end with the publication of the HIPPARCOS and Tycho Star Catalogues later this decade. Only then will an astrophysical exploitation of the results commence. Proposals have already been submitted to ESA to follow up its successful breakthrough into space astrometry with new missions proposed for launch early in the next millennium. Note for Editors : The Hipparcos mission was accepted within the ESA mandatory scientific programme in 1980. With overall management by ESA, the system

  10. Hipparcos: mission accomplished

    NASA Astrophysics Data System (ADS)

    1993-08-01

    satellite. These catalogues will be of enormous value in astronomers' attempts to understand and describe the properties and evolution of stars, and the dynamical motion of these stars within our Galaxy. In the process, HIPPARCOS has discovered many thousands of new binary star systems, measured the precise light variations of many hundreds of thousands of stars over its operational lifetime, and has provided an accurate and independent validation of the predictions of General Relativity. Scientists working with ESA on the HIPPARCOS programme, were at ESOC on 13-14 July to review the progress of the data processing, and to examine whether any further efforts might allow the satellite to continue operating. "All of us are sorry to see the end of this remarkable satellite" said Dr. Michael Perryman, ESA scientist responsible for HIPPARCOS, "On the other end, we are delighted that it has delivered substantially more than it had been originally designed for. When our final results are published, some very interesting new insights into the nature of our Galaxy, its structure and its evolution, will emerge" he added. A large team of scientists from the various ESA member states are responsible for the analysis and interpretation of the vast amount of data that has been generated by the HIPPARCOS satellite, in what is considered to be the largest single data processing challenge ever undertaken in astronomy. Working with ESA since the time of the mission acceptance in 1980, their immediate work will only end with the publication of the HIPPARCOS and Tycho Star Catalogues later this decade. Only then will an astrophysical exploitation of the results commence. Proposals have already been submitted to ESA to follow up its successful breakthrough into space astrometry with new missions proposed for launch early in the next millennium. Note for Editors : The Hipparcos mission was accepted within the ESA mandatory scientific programme in 1980. With overall management by ESA, the system

  11. ADVANCED FUELS CAMPAIGN 2013 ACCOMPLISHMENTS

    SciTech Connect

    Not Listed

    2013-10-01

    The mission of the Advanced Fuels Campaign (AFC) is to perform Research, Development, and Demonstration (RD&D) activities for advanced fuel forms (including cladding) to enhance the performance and safety of the nation’s current and future reactors; enhance proliferation resistance of nuclear fuel; effectively utilize nuclear energy resources; and address the longer-term waste management challenges. This includes development of a state-of-the art Research and Development (R&D) infrastructure to support the use of “goal-oriented science-based approach.” In support of the Fuel Cycle Research and Development (FCRD) program, AFC is responsible for developing advanced fuels technologies to support the various fuel cycle options defined in the Department of Energy (DOE) Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. Accomplishments made during fiscal year (FY) 2013 are highlighted in this report, which focuses on completed work and results. The process details leading up to the results are not included; however, the technical contact is provided for each section.

  12. Data Mining and Pattern Recognition Models for Identifying Inherited Diseases: Challenges and Implications.

    PubMed

    Iddamalgoda, Lahiru; Das, Partha S; Aponso, Achala; Sundararajan, Vijayaraghava S; Suravajhala, Prashanth; Valadi, Jayaraman K

    2016-01-01

    Data mining and pattern recognition methods reveal interesting findings in genetic studies, especially on how the genetic makeup is associated with inherited diseases. Although researchers have proposed various data mining models for biomedical approaches, there remains a challenge in accurately prioritizing the single nucleotide polymorphisms (SNP) associated with the disease. In this commentary, we review the state-of-art data mining and pattern recognition models for identifying inherited diseases and deliberate the need of binary classification- and scoring-based prioritization methods in determining causal variants. While we discuss the pros and cons associated with these methods known, we argue that the gene prioritization methods and the protein interaction (PPI) methods in conjunction with the K nearest neighbors' could be used in accurately categorizing the genetic factors in disease causation. PMID:27559342

  13. The challenge of identifying non-intentionally added substances from food packaging materials: a review.

    PubMed

    Nerin, C; Alfaro, P; Aznar, M; Domeño, C

    2013-05-01

    Packaged food can contain non-intentionally added substances (NIAS) as a result of reaction and degradation processes or the presence of impurities in the raw materials used for the packaging production. This manuscript reviews the evidence of NIAS and their possible origin. One of the most challenging and difficult tasks when a sample of packaging materials arrives at the laboratory is knowing the procedure to apply for identifying the unknown compounds. This work proposes an analytical procedure for sample treatment, applicable to polymers as well as to migration samples, and for NIAS identification. The identification protocol comprises the determination of both volatile and non-volatile compounds. A review is presented of the most novel analytical techniques used for identification purposes, particularly high resolution mass spectrometry (HRMS). PMID:23601971

  14. Data Mining and Pattern Recognition Models for Identifying Inherited Diseases: Challenges and Implications

    PubMed Central

    Iddamalgoda, Lahiru; Das, Partha S.; Aponso, Achala; Sundararajan, Vijayaraghava S.; Suravajhala, Prashanth; Valadi, Jayaraman K.

    2016-01-01

    Data mining and pattern recognition methods reveal interesting findings in genetic studies, especially on how the genetic makeup is associated with inherited diseases. Although researchers have proposed various data mining models for biomedical approaches, there remains a challenge in accurately prioritizing the single nucleotide polymorphisms (SNP) associated with the disease. In this commentary, we review the state-of-art data mining and pattern recognition models for identifying inherited diseases and deliberate the need of binary classification- and scoring-based prioritization methods in determining causal variants. While we discuss the pros and cons associated with these methods known, we argue that the gene prioritization methods and the protein interaction (PPI) methods in conjunction with the K nearest neighbors' could be used in accurately categorizing the genetic factors in disease causation. PMID:27559342

  15. NASA space biology accomplishments, 1982

    NASA Technical Reports Server (NTRS)

    Halstead, T. W.; Pleasant, L. G.

    1983-01-01

    Summaries of NASA's Space Biology Program projects are provided. The goals, objectives, accomplishments, and future plans of each project are described in this publication as individual technical summaries.

  16. Challenges in identifying cancer genes by analysis of exome sequencing data.

    PubMed

    Hofree, Matan; Carter, Hannah; Kreisberg, Jason F; Bandyopadhyay, Sourav; Mischel, Paul S; Friend, Stephen; Ideker, Trey

    2016-01-01

    Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysis methods to specifically recover known cancer genes. While some cancer genes are identified by analysis of recurrence, spatial clustering or predicted impact of somatic mutations, many remain undetected due to lack of power to discriminate driver mutations from the background mutational load (13-60% recall of cancer genes impacted by somatic single-nucleotide variants, depending on the method). Cancer genes not detected by mutation recurrence also tend to be missed by all types of exome analysis. Nonetheless, these genes are implicated by other experiments such as functional genetic screens and expression profiling. These challenges are only partially addressed by increasing sample size and will likely hold even as greater numbers of tumours are analysed. PMID:27417679

  17. Challenges in identifying cancer genes by analysis of exome sequencing data

    PubMed Central

    Hofree, Matan; Carter, Hannah; Kreisberg, Jason F.; Bandyopadhyay, Sourav; Mischel, Paul S.; Friend, Stephen; Ideker, Trey

    2016-01-01

    Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysis methods to specifically recover known cancer genes. While some cancer genes are identified by analysis of recurrence, spatial clustering or predicted impact of somatic mutations, many remain undetected due to lack of power to discriminate driver mutations from the background mutational load (13–60% recall of cancer genes impacted by somatic single-nucleotide variants, depending on the method). Cancer genes not detected by mutation recurrence also tend to be missed by all types of exome analysis. Nonetheless, these genes are implicated by other experiments such as functional genetic screens and expression profiling. These challenges are only partially addressed by increasing sample size and will likely hold even as greater numbers of tumours are analysed. PMID:27417679

  18. The IGSN Experience: Successes and Challenges of Implementing Persistent Identifiers for Samples

    NASA Astrophysics Data System (ADS)

    Lehnert, Kerstin; Arko, Robert

    2016-04-01

    Physical samples collected and studied in the Earth sciences represent both a research resource and a research product in the Earth Sciences. As such they need to be properly managed, curated, documented, and cited to ensure re-usability and utility for future science, reproducibility of the data generated by their study, and credit for funding agencies and researchers who invested substantial resources and intellectual effort into their collection and curation. Use of persistent and unique identifiers and deposition of metadata in a persistent registry are therefore as important for physical samples as they are for digital data. The International Geo Sample Number (IGSN) is a persistent, globally unique identifier. Its adoption by individual investigators, repository curators, publishers, and data managers is rapidly growing world-wide. This presentation will provide an analysis of the development and implementation path of the IGSN and relevant insights and experiences gained along its way. Development of the IGSN started in 2004 as part of a US NSF-funded project to establish a registry for sample metadata, the System for Earth Sample Registration (SESAR). The initial system provided a centralized solution for users to submit information about their samples and obtain IGSNs and bar codes. Challenges encountered during this initial phase related to defining the scope of the registry, granularity of registered objects, responsibilities of relevant actors, and workflows, and designing the registry's metadata schema, its user interfaces, and the identifier itself, including its syntax. The most challenging task though was to make the IGSN an integral part of personal and institutional sample management, digital management of sample-based data, and data publication on a global scale. Besides convincing individual researchers, curators, editors and publishers, as well as data managers in US and non-US academia, state and federal agencies, the PIs of the SESAR project

  19. Mass Spectrometry-Based Methods for Identifying Oxidized Proteins in Disease: Advances and Challenges

    PubMed Central

    Verrastro, Ivan; Pasha, Sabah; Tveen Jensen, Karina; Pitt, Andrew R.; Spickett, Corinne M.

    2015-01-01

    Many inflammatory diseases have an oxidative aetiology, which leads to oxidative damage to biomolecules, including proteins. It is now increasingly recognized that oxidative post-translational modifications (oxPTMs) of proteins affect cell signalling and behaviour, and can contribute to pathology. Moreover, oxidized proteins have potential as biomarkers for inflammatory diseases. Although many assays for generic protein oxidation and breakdown products of protein oxidation are available, only advanced tandem mass spectrometry approaches have the power to localize specific oxPTMs in identified proteins. While much work has been carried out using untargeted or discovery mass spectrometry approaches, identification of oxPTMs in disease has benefitted from the development of sophisticated targeted or semi-targeted scanning routines, combined with chemical labeling and enrichment approaches. Nevertheless, many potential pitfalls exist which can result in incorrect identifications. This review explains the limitations, advantages and challenges of all of these approaches to detecting oxidatively modified proteins, and provides an update on recent literature in which they have been used to detect and quantify protein oxidation in disease. PMID:25874603

  20. The Next Challenge for Psychiatric Genetics: Characterizing the Risk Associated with Identified Genes

    PubMed Central

    Dick, Danielle M.; Rose, Richard J.; Kaprio, Jaakko

    2006-01-01

    Background As advances in genetics further our ability to identify genes influencing psychiatric disorders, the next challenge facing psychiatric genetics is to characterize the risk associated with specific genetic variants in order to better understand how these susceptibility genes are involved in the pathways leading to illness. Methods To further this goal, findings from behavior genetic analyses about how genetic influences act can be used to guide hypothesis testing about the effects associated with specific genes. Results Using the phenotype of alcohol dependence as an example, this paper provides an overview of how the integration of behavioral and statistical genetics can advance our knowledge about the genetics of psychiatric disorders. Areas currently being investigated in behavior genetics include careful delineation of phenotypes, to examine the heritability of various aspects of normal and abnormal behavior; developmental changes in the nature and magnitude of genetic and environmental effects; the extent to which different behaviors are influenced by common genes; and different forms of gene-environment correlation and interaction. Conclusions Understanding how specific genes are involved in these processes has the potential to significantly enhance our understanding of the development of psychiatric disorders. PMID:17162621

  1. 77 FR 48162 - Announcement of Requirements and Registration for the Challenge To Identify Audacious Goals in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... Audacious Goals in Vision Research and Blindness Rehabilitation (Challenge) to stimulate innovation in... proposed goal is bold, daring, original or unconventional, exceptionally innovative, creative, novel,...

  2. Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.

    PubMed

    Rose, Amy E; Poliseno, Laura; Wang, Jinhua; Clark, Michael; Pearlman, Alexander; Wang, Guimin; Vega Y Saenz de Miera, Eleazar C; Medicherla, Ratna; Christos, Paul J; Shapiro, Richard; Pavlick, Anna; Darvishian, Farbod; Zavadil, Jiri; Polsky, David; Hernando, Eva; Ostrer, Harry; Osman, Iman

    2011-04-01

    Superficial spreading melanoma (SSM) and nodular melanoma (NM) are believed to represent sequential phases of linear progression from radial to vertical growth. Several lines of clinical, pathologic, and epidemiologic evidence suggest, however, that SSM and NM might be the result of independent pathways of tumor development. We utilized an integrative genomic approach that combines single nucleotide polymorphism array (6.0; Affymetrix) with gene expression array (U133A 2.0; Affymetrix) to examine molecular differences between SSM and NM. Pathway analysis of the most differentially expressed genes between SSM and NM (N = 114) revealed significant differences related to metabolic processes. We identified 8 genes (DIS3, FGFR1OP, G3BP2, GALNT7, MTAP, SEC23IP, USO1, and ZNF668) in which NM/SSM-specific copy number alterations correlated with differential gene expression (P < 0.05; Spearman's rank). SSM-specific genomic deletions in G3BP2, MTAP, and SEC23IP were independently verified in two external data sets. Forced overexpression of metabolism-related gene MTAP (methylthioadenosine phosphorylase) in SSM resulted in reduced cell growth. The differential expression of another metabolic-related gene, aldehyde dehydrogenase 7A1 (ALDH7A1), was validated at the protein level by using tissue microarrays of human melanoma. In addition, we show that the decreased ALDH7A1 expression in SSM may be the result of epigenetic modifications. Our data reveal recurrent genomic deletions in SSM not present in NM, which challenge the linear model of melanoma progression. Furthermore, our data suggest a role for altered regulation of metabolism-related genes as a possible cause of the different clinical behavior of SSM and NM. PMID:21343389

  3. Multiple Methods for Identifying Outcomes of a High Challenge Adventure Activity

    ERIC Educational Resources Information Center

    Davidson, Curt; Ewert, Alan; Chang, Yun

    2016-01-01

    The purpose of this study was to provide insight into what occurs in moments of high challenge within participants during an outdoor adventure education (OAE) program. Given the inherent risk and remote locations often associated with OAE programs, it has remained challenging to measure selected psychological constructs while the program is taking…

  4. Advanced Fuels Campaign 2012 Accomplishments

    SciTech Connect

    Not Listed

    2012-11-01

    The Advanced Fuels Campaign (AFC) under the Fuel Cycle Research and Development (FCRD) program is responsible for developing fuels technologies to support the various fuel cycle options defined in the DOE Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. The fiscal year 2012 (FY 2012) accomplishments are highlighted below. Kemal Pasamehmetoglu is the National Technical Director for AFC.

  5. Infant Mortality: 1989 Research Accomplishments.

    ERIC Educational Resources Information Center

    National Inst. of Child Health and Human Development (NIH), Bethesda, MD.

    Collected in this document are reports of the National Institutes of Health's 1989 accomplishments in research on the problem of infant mortality. Reports are provided by the: (1) National Institute of Child Health and Human Development; (2) National Cancer Institute; (3) National Heart, Lung, and Blood Institute; (4) National Institute of…

  6. The Joint Accomplishment of Identity

    ERIC Educational Resources Information Center

    Hand, Victoria; Gresalfi, Melissa

    2015-01-01

    Identity has become a central concept in the analysis of learning from social perspectives. In this article, we draw on a situative perspective to conceptualize identity as a "joint accomplishment" between individuals and their interactions with norms, practices, cultural tools, relationships, and institutional and cultural contexts.…

  7. Pharmaceutical policies in a crisis? Challenges and solutions identified at the PPRI Conference.

    PubMed

    Vogler, Sabine; Zimmermann, Nina; Ferrario, Alessandra; Wirtz, Veronika J; de Joncheere, Kees; Pedersen, Hanne Bak; Dedet, Guillaume; Paris, Valérie; Mantel-Teeuwisse, Aukje K; Babar, Zaheer-Ud-Din

    2016-01-01

    In October 2015, the third international Pharmaceutical Pricing and Reimbursement Information (PPRI) Conference was held in Vienna to foster discussion on challenges in pricing and reimbursement policies for medicines. The research presented highlighted that commonly used pharmaceutical pricing and reimbursement policies are not sufficiently effective to address current challenges. Conference participants called for fundamental reforms to ensure access to medicines, particularly to new and potentially more effective and/or safe medicines, while safeguarding the financial sustainability of health systems and working towards universal health coverage. PMID:26981252

  8. Financial sustainability of academic health centers: identifying challenges and strategic responses.

    PubMed

    Stimpson, Jim P; Li, Tao; Shiyanbola, Oyewale O; Jacobson, Janelle J

    2014-06-01

    Academic health centers (AHCs) play a vital role in the health care system. The training of health care personnel and delivery of health care services, especially to the most complex and financially challenged patients, has been a responsibility increasingly shouldered by AHCs over the years. Additionally, AHCs play a significant role in researching and developing new treatment protocols, including discovering and validating new health technologies. However, AHCs face unique financial challenges in fulfilling their social mission in the health care system. Reforms being implemented under the Affordable Care Act and shifting economic patterns are threatening the financial sustainability of AHCs.The authors review challenges facing AHCs, including training new health care professionals with fewer funding resources, disproportionate clinical care of complex and costly patients, charity care to uninsured and underinsured, and reduced research funding opportunities. Then, they provide a review of some potential solutions to these challenges, including new reimbursement methods, improvements in operational efficiency, price regulation, subsidization of education, improved decision making and communication, utilization of industrial management tools, and increasing internal and external cooperation. Devising solutions to the evolving problems of AHCs is crucial to improving health care delivery in the United States. Most likely, a combination of market, government, and system reforms will be needed to improve the viability of AHCs and assist them in fulfilling their social and organizational missions. PMID:24871234

  9. Supporting Schools in Identifying and Safeguarding the Needs of Disabled Children: The Challenges for Data Collection

    ERIC Educational Resources Information Center

    Porter, Jill; Daniels, Harry; Martin, Sue; Hacker, Jayne; Feiler, Anthony; Georgeson, Jan

    2012-01-01

    Conceptualisations of disability that emphasise the contextual and cultural nature of disability and the embodiment of these within a national system of data collection present a number of challenges especially where this process is devolved to schools. The requirement for measures based on contextual and subjective experiences gives rise to…

  10. Advanced Fuels Campaign FY 2015 Accomplishments Report

    SciTech Connect

    Braase, Lori Ann; Carmack, William Jonathan

    2015-10-29

    The mission of the Advanced Fuels Campaign (AFC) is to perform research, development, and demonstration (RD&D) activities for advanced fuel forms (including cladding) to enhance the performance and safety of the nation’s current and future reactors; enhance proliferation resistance of nuclear fuel; effectively utilize nuclear energy resources; and address the longer-term waste management challenges. This report is a compilation of technical accomplishment summaries for FY-15. Emphasis is on advanced accident-tolerant LWR fuel systems, advanced transmutation fuels technologies, and capability development.

  11. Identifying and meeting the challenges of insulin therapy in type 2 diabetes

    PubMed Central

    Sorli, Christopher; Heile, Michael K

    2014-01-01

    Type 2 diabetes mellitus (T2DM) is a chronic illness that requires clinical recognition and treatment of the dual pathophysiologic entities of altered glycemic control and insulin resistance to reduce the risk of long-term micro- and macrovascular complications. Although insulin is one of the most effective and widely used therapeutic options in the management of diabetes, it is used by less than one-half of patients for whom it is recommended. Clinician-, patient-, and health care system-related challenges present numerous obstacles to insulin use in T2DM. Clinicians must remain informed about new insulin products, emerging technologies, and treatment options that have the potential to improve adherence to insulin therapy while optimizing glycemic control and mitigating the risks of therapy. Patient-related challenges may be overcome by actively listening to the patient’s fears and concerns regarding insulin therapy and by educating patients about the importance, rationale, and evolving role of insulin in individualized self-treatment regimens. Enlisting the services of Certified Diabetes Educators and office personnel can help in addressing patient-related challenges. Self-management of diabetes requires improved patient awareness regarding the importance of lifestyle modifications, self-monitoring, and/or continuous glucose monitoring, improved methods of insulin delivery (eg, insulin pens), and the enhanced convenience and safety provided by insulin analogs. Health care system-related challenges may be improved through control of the rising cost of insulin therapy while making it available to patients. To increase the success rate of treatment of T2DM, the 2012 position statement from the American Diabetes Association and the European Association for the Study of Diabetes focused on individualized patient care and provided clinicians with general treatment goals, implementation strategies, and tools to evaluate the quality of care. PMID:25061317

  12. Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.

    PubMed

    van Os, Jim; Rutten, Bart P; Myin-Germeys, Inez; Delespaul, Philippe; Viechtbauer, Wolfgang; van Zelst, Catherine; Bruggeman, Richard; Reininghaus, Ulrich; Morgan, Craig; Murray, Robin M; Di Forti, Marta; McGuire, Philip; Valmaggia, Lucia R; Kempton, Matthew J; Gayer-Anderson, Charlotte; Hubbard, Kathryn; Beards, Stephanie; Stilo, Simona A; Onyejiaka, Adanna; Bourque, Francois; Modinos, Gemma; Tognin, Stefania; Calem, Maria; O'Donovan, Michael C; Owen, Michael J; Holmans, Peter; Williams, Nigel; Craddock, Nicholas; Richards, Alexander; Humphreys, Isla; Meyer-Lindenberg, Andreas; Leweke, F Markus; Tost, Heike; Akdeniz, Ceren; Rohleder, Cathrin; Bumb, J Malte; Schwarz, Emanuel; Alptekin, Köksal; Üçok, Alp; Saka, Meram Can; Atbaşoğlu, E Cem; Gülöksüz, Sinan; Gumus-Akay, Guvem; Cihan, Burçin; Karadağ, Hasan; Soygür, Haldan; Cankurtaran, Eylem Şahin; Ulusoy, Semra; Akdede, Berna; Binbay, Tolga; Ayer, Ahmet; Noyan, Handan; Karadayı, Gülşah; Akturan, Elçin; Ulaş, Halis; Arango, Celso; Parellada, Mara; Bernardo, Miguel; Sanjuán, Julio; Bobes, Julio; Arrojo, Manuel; Santos, Jose Luis; Cuadrado, Pedro; Rodríguez Solano, José Juan; Carracedo, Angel; García Bernardo, Enrique; Roldán, Laura; López, Gonzalo; Cabrera, Bibiana; Cruz, Sabrina; Díaz Mesa, Eva Ma; Pouso, María; Jiménez, Estela; Sánchez, Teresa; Rapado, Marta; González, Emiliano; Martínez, Covadonga; Sánchez, Emilio; Olmeda, Ma Soledad; de Haan, Lieuwe; Velthorst, Eva; van der Gaag, Mark; Selten, Jean-Paul; van Dam, Daniella; van der Ven, Elsje; van der Meer, Floor; Messchaert, Elles; Kraan, Tamar; Burger, Nadine; Leboyer, Marion; Szoke, Andrei; Schürhoff, Franck; Llorca, Pierre-Michel; Jamain, Stéphane; Tortelli, Andrea; Frijda, Flora; Vilain, Jeanne; Galliot, Anne-Marie; Baudin, Grégoire; Ferchiou, Aziz; Richard, Jean-Romain; Bulzacka, Ewa; Charpeaud, Thomas; Tronche, Anne-Marie; De Hert, Marc; van Winkel, Ruud; Decoster, Jeroen; Derom, Catherine; Thiery, Evert; Stefanis, Nikos C; Sachs, Gabriele; Aschauer, Harald; Lasser, Iris; Winklbaur, Bernadette; Schlögelhofer, Monika; Riecher-Rössler, Anita; Borgwardt, Stefan; Walter, Anna; Harrisberger, Fabienne; Smieskova, Renata; Rapp, Charlotte; Ittig, Sarah; Soguel-dit-Piquard, Fabienne; Studerus, Erich; Klosterkötter, Joachim; Ruhrmann, Stephan; Paruch, Julia; Julkowski, Dominika; Hilboll, Desiree; Sham, Pak C; Cherny, Stacey S; Chen, Eric Y H; Campbell, Desmond D; Li, Miaoxin; Romeo-Casabona, Carlos María; Emaldi Cirión, Aitziber; Urruela Mora, Asier; Jones, Peter; Kirkbride, James; Cannon, Mary; Rujescu, Dan; Tarricone, Ilaria; Berardi, Domenico; Bonora, Elena; Seri, Marco; Marcacci, Thomas; Chiri, Luigi; Chierzi, Federico; Storbini, Viviana; Braca, Mauro; Minenna, Maria Gabriella; Donegani, Ivonne; Fioritti, Angelo; La Barbera, Daniele; La Cascia, Caterina Erika; Mulè, Alice; Sideli, Lucia; Sartorio, Rachele; Ferraro, Laura; Tripoli, Giada; Seminerio, Fabio; Marinaro, Anna Maria; McGorry, Patrick; Nelson, Barnaby; Amminger, G Paul; Pantelis, Christos; Menezes, Paulo R; Del-Ben, Cristina M; Gallo Tenan, Silvia H; Shuhama, Rosana; Ruggeri, Mirella; Tosato, Sarah; Lasalvia, Antonio; Bonetto, Chiara; Ira, Elisa; Nordentoft, Merete; Krebs, Marie-Odile; Barrantes-Vidal, Neus; Cristóbal, Paula; Kwapil, Thomas R; Brietzke, Elisa; Bressan, Rodrigo A; Gadelha, Ary; Maric, Nadja P; Andric, Sanja; Mihaljevic, Marina; Mirjanic, Tijana

    2014-07-01

    Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G × E), however, so far, thorough replication of findings is rare and G × E research still faces several conceptual and methodological challenges. In this article, we aim to review these recent developments and illustrate how integrated, large-scale investigations may overcome contemporary challenges in G × E research, drawing on the example of a large, international, multi-center study into the identification and translational application of G × E in schizophrenia. While such investigations are now well underway, new challenges emerge for G × E research from late-breaking evidence that genetic variation and environmental exposures are, to a significant degree, shared across a range of psychiatric disorders, with potential overlap in phenotype. PMID:24860087

  13. Overcoming Challenges in Conducting Clinical Trials in Minority Populations: Identifying and Testing What Works

    PubMed Central

    Azuine, Romuladus E.; Ekejiuba, Sussan E.

    2015-01-01

    Participation in clinical trials is one of the greatest gifts that humanity can give to the fields of medicine and public health. Clinical trials are central in public health’s mission to advance drug discovery. The enrollment and retention of participants, especially minority populations, is one of the most practical challenges of successfully implementing a clinical trial. In spite of these challenges, there are many reasons why a broader public participation in clinical trials is critical. The ability to generalize the scientific findings and the principles of equity, justice, and beneficence require an equitable distribution of the risks, benefits, and burdens of research for all classes and groups of people. A new methodology article published in this journal presents a promising framework for addressing minority recruitment and retention using what is known and using it innovatively to address a difficult problem facing clinical trials and public health. The innovative application of what is known in addressing a challenging problem, as this article presents, is worth the reading of all those interested in scientifically rigorous and ethically sound clinical trials that substantially comprise of diverse populations.

  14. Identifying Gene-Environment Interactions in Schizophrenia: Contemporary Challenges for Integrated, Large-scale Investigations

    PubMed Central

    2014-01-01

    Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G × E), however, so far, thorough replication of findings is rare and G × E research still faces several conceptual and methodological challenges. In this article, we aim to review these recent developments and illustrate how integrated, large-scale investigations may overcome contemporary challenges in G × E research, drawing on the example of a large, international, multi–center study into the identification and translational application of G × E in schizophrenia. While such investigations are now well underway, new challenges emerge for G × E research from late-breaking evidence that genetic variation and environmental exposures are, to a significant degree, shared across a range of psychiatric disorders, with potential overlap in phenotype. PMID:24860087

  15. Identifying disease mutations in genomic medicine settings: current challenges and how to accelerate progress.

    PubMed

    Lyon, Gholson J; Wang, Kai

    2012-01-01

    The pace of exome and genome sequencing is accelerating, with the identification of many new disease-causing mutations in research settings, and it is likely that whole exome or genome sequencing could have a major impact in the clinical arena in the relatively near future. However, the human genomics community is currently facing several challenges, including phenotyping, sample collection, sequencing strategies, bioinformatics analysis, biological validation of variant function, clinical interpretation and validity of variant data, and delivery of genomic information to various constituents. Here we review these challenges and summarize the bottlenecks for the clinical application of exome and genome sequencing, and we discuss ways for moving the field forward. In particular, we urge the need for clinical-grade sample collection, high-quality sequencing data acquisition, digitalized phenotyping, rigorous generation of variant calls, and comprehensive functional annotation of variants. Additionally, we suggest that a 'networking of science' model that encourages much more collaboration and online sharing of medical history, genomic data and biological knowledge, including among research participants and consumers/patients, will help establish causation and penetrance for disease causal variants and genes. As we enter this new era of genomic medicine, we envision that consumer-driven and consumer-oriented efforts will take center stage, thus allowing insights from the human genome project to translate directly back into individualized medicine. PMID:22830651

  16. Identifying disease mutations in genomic medicine settings: current challenges and how to accelerate progress

    PubMed Central

    2012-01-01

    The pace of exome and genome sequencing is accelerating, with the identification of many new disease-causing mutations in research settings, and it is likely that whole exome or genome sequencing could have a major impact in the clinical arena in the relatively near future. However, the human genomics community is currently facing several challenges, including phenotyping, sample collection, sequencing strategies, bioinformatics analysis, biological validation of variant function, clinical interpretation and validity of variant data, and delivery of genomic information to various constituents. Here we review these challenges and summarize the bottlenecks for the clinical application of exome and genome sequencing, and we discuss ways for moving the field forward. In particular, we urge the need for clinical-grade sample collection, high-quality sequencing data acquisition, digitalized phenotyping, rigorous generation of variant calls, and comprehensive functional annotation of variants. Additionally, we suggest that a 'networking of science' model that encourages much more collaboration and online sharing of medical history, genomic data and biological knowledge, including among research participants and consumers/patients, will help establish causation and penetrance for disease causal variants and genes. As we enter this new era of genomic medicine, we envision that consumer-driven and consumer-oriented efforts will take center stage, thus allowing insights from the human genome project to translate directly back into individualized medicine. PMID:22830651

  17. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

    PubMed Central

    Wilke, Russell A.; Lin, Debbie W.; Roden, Dan M.; Watkins, Paul B.; Flockhart, David; Zineh, Issam; Giacomini, Kathleen M.; Krauss, Ronald M.

    2009-01-01

    Serious adverse drug reactions (SADRs) are a major cause of morbidity and mortality worldwide. Some SADRs may be predictable, based upon a drug's pharmacodynamic and pharmacokinetic properties. Many, however, appear to be idiosyncratic. Genetic factors may underlie susceptibility to SADRs and the identification of predisposing genotypes may improve patient management through the prospective selection of appropriate candidates. Here we discuss three specific SADRs with an emphasis on genetic risk factors. These SADRs, selected based on wide-sweeping clinical interest, are drug-induced liver injury, statin-induced myotoxicity and drug-induced long QT and torsades de pointes. Key challenges for the discovery of predictive risk alleles for these SADRs are also considered. PMID:17971785

  18. Identifying barriers and catalysts to fostering pro-environmental behavior: opportunities and challenges for community psychology.

    PubMed

    Quimby, Christine C; Angelique, Holly

    2011-06-01

    In this paper, we report on an exploratory study of perceived barriers and catalysts to increasing pro-environmental behavior among people associated with the environmental movement. Perceived barriers include time, money, low efficacy and hopelessness. Catalysts focus on changing social norms, especially through education and institutional support. We discuss the tragedy of the commons and free-riding as impediments to change. We use this study as an entryway to hypothesize opportunities and challenges that community psychologists face in motivating and supporting actions to reduce the impact of global climate change. We provide examples of how community psychologists can foster these changes. In short, we argue that community psychology is well positioned to take a leading role in the fight for a carbon neutral future. PMID:21203832

  19. Challenging dedifferentiated liposarcoma identified by MDM2-amplification, a report of two cases

    PubMed Central

    2014-01-01

    Background Liposarcoma is the most frequent soft tissue sarcoma. Well differentiated liposarcoma may progress into dedifferentiated liposarcoma with pleomorphic histology. A minority additionally features myogenic, osteo- or chondrosarcomatous heterologous differentiation. Genomic amplification of the Mouse double minute 2 homolog (MDM2) locus is characteristic for well differentiated and dedifferentiated liposarcomas. Detection of MDM2 amplification may supplement histopathology and aid to distinguish liposarcoma from other soft tissue neoplasia. Case presentation Here we present two cases of dedifferentiated liposarcoma with challenging presentation. Case 1 features a myogenic component. As the tumour infiltrated the abdominal muscles and showed immunohistochemical expression of myogenic proteins, rhabdomyosarcoma had to be ruled out. Case 2 has an osteosarcomatous component resembling extraosseous osteosarcoma. The MDM2 status was determined in both cases and helped making the correct diagnosis. Overexpression of MDM2 and co-overexpression of Cyclin-dependent kinase 4 is demonstrated by immunohistochemistry. The underlying MDM2 amplification is shown by fluorescence in situ hybridisation. Since low grade osteosarcoma may also harbour MDM2 amplification it is emphasised that the amplification has to be present in the lipomatous parts of the tumour to distinguish liposarcoma from extraosseous osteosarcoma. Conclusions The two cases exemplify challenges in the diagnoses of dedifferentiated liposarcoma. Liposarcoma often has pleomorphic histology and additionally may feature heterologous components that mimic other soft tissue neoplasms. Amplification of MDM2 is characteristic for well differentiated and dedifferentiated liposarcomas. Determination of the MDM2 status by in situ hybridisation may assist histopathology and help to rule out differential diagnoses. PMID:25126005

  20. Finding and identifying the viral needle in the metagenomic haystack: trends and challenges

    PubMed Central

    Soueidan, Hayssam; Schmitt, Louise-Amélie; Candresse, Thierry; Nikolski, Macha

    2015-01-01

    Collectively, viruses have the greatest genetic diversity on Earth, occupy extremely varied niches and are likely able to infect all living organisms. Viral infections are an important issue for human health and cause considerable economic losses when agriculturally important crops or husbandry animals are infected. The advent of metagenomics has provided a precious tool to study viruses by sampling them in natural environments and identifying the genomic composition of a sample. However, reaching a clear recognition and taxonomic assignment of the identified viruses has been hampered by the computational difficulty of these problems. In this perspective paper we examine the trends in current research for the identification of viral sequences in a metagenomic sample, pinpoint the intrinsic computational difficulties for the identification of novel viral sequences within metagenomic samples, and suggest possible avenues to overcome them. PMID:25610431

  1. Challenges in identifying sites climatically matched to the native ranges of animal invaders

    USGS Publications Warehouse

    Rodda, G.H.; Jarnevich, C.S.; Reed, R.N.

    2011-01-01

    Background: Species distribution models are often used to characterize a species' native range climate, so as to identify sites elsewhere in the world that may be climatically similar and therefore at risk of invasion by the species. This endeavor provoked intense public controversy over recent attempts to model areas at risk of invasion by the Indian Python (Python molurus). We evaluated a number of MaxEnt models on this species to assess MaxEnt's utility for vertebrate climate matching. Methodology/Principal Findings: Overall, we found MaxEnt models to be very sensitive to modeling choices and selection of input localities and background regions. As used, MaxEnt invoked minimal protections against data dredging, multi-collinearity of explanatory axes, and overfitting. As used, MaxEnt endeavored to identify a single ideal climate, whereas different climatic considerations may determine range boundaries in different parts of the native range. MaxEnt was extremely sensitive to both the choice of background locations for the python, and to selection of presence points: inclusion of just four erroneous localities was responsible for Pyron et al.'s conclusion that no additional portions of the U.S. mainland were at risk of python invasion. When used with default settings, MaxEnt overfit the realized climate space, identifying models with about 60 parameters, about five times the number of parameters justifiable when optimized on the basis of Akaike's Information Criterion. Conclusions/Significance: When used with default settings, MaxEnt may not be an appropriate vehicle for identifying all sites at risk of colonization. Model instability and dearth of protections against overfitting, multi-collinearity, and data dredging may combine with a failure to distinguish fundamental from realized climate envelopes to produce models of limited utility. A priori identification of biologically realistic model structure, combined with computational protections against these

  2. A Likelihood-Based Approach to Identifying Contaminated Food Products Using Sales Data: Performance and Challenges

    PubMed Central

    Kaufman, James; Lessler, Justin; Harry, April; Edlund, Stefan; Hu, Kun; Douglas, Judith; Thoens, Christian; Appel, Bernd; Käsbohrer, Annemarie; Filter, Matthias

    2014-01-01

    Foodborne disease outbreaks of recent years demonstrate that due to increasingly interconnected supply chains these type of crisis situations have the potential to affect thousands of people, leading to significant healthcare costs, loss of revenue for food companies, and—in the worst cases—death. When a disease outbreak is detected, identifying the contaminated food quickly is vital to minimize suffering and limit economic losses. Here we present a likelihood-based approach that has the potential to accelerate the time needed to identify possibly contaminated food products, which is based on exploitation of food products sales data and the distribution of foodborne illness case reports. Using a real world food sales data set and artificially generated outbreak scenarios, we show that this method performs very well for contamination scenarios originating from a single “guilty” food product. As it is neither always possible nor necessary to identify the single offending product, the method has been extended such that it can be used as a binary classifier. With this extension it is possible to generate a set of potentially “guilty” products that contains the real outbreak source with very high accuracy. Furthermore we explore the patterns of food distributions that lead to “hard-to-identify” foods, the possibility of identifying these food groups a priori, and the extent to which the likelihood-based method can be used to quantify uncertainty. We find that high spatial correlation of sales data between products may be a useful indicator for “hard-to-identify” products. PMID:24992565

  3. Challenges to identifying actual diabetes case-mix complexity and total treatment charges.

    PubMed

    Baker, T; Ertle, A; Cave, D G

    1997-04-01

    Patient management programs are being used to improve the quality of care and decrease charges for both high-cost and potential high-cost claimants. Adequate information is key to program development, planning, and implementation. Claims-based data are a ready source of valuable information, but without proper processing, true case-mix complexity and total charges for patients will not be identified. PMID:10166808

  4. Challenges in Identifying Sites Climatically Matched to the Native Ranges of Animal Invaders

    PubMed Central

    Rodda, Gordon H.; Jarnevich, Catherine S.; Reed, Robert N.

    2011-01-01

    Background Species distribution models are often used to characterize a species' native range climate, so as to identify sites elsewhere in the world that may be climatically similar and therefore at risk of invasion by the species. This endeavor provoked intense public controversy over recent attempts to model areas at risk of invasion by the Indian Python (Python molurus). We evaluated a number of MaxEnt models on this species to assess MaxEnt's utility for vertebrate climate matching. Methodology/Principal Findings Overall, we found MaxEnt models to be very sensitive to modeling choices and selection of input localities and background regions. As used, MaxEnt invoked minimal protections against data dredging, multi-collinearity of explanatory axes, and overfitting. As used, MaxEnt endeavored to identify a single ideal climate, whereas different climatic considerations may determine range boundaries in different parts of the native range. MaxEnt was extremely sensitive to both the choice of background locations for the python, and to selection of presence points: inclusion of just four erroneous localities was responsible for Pyron et al.'s conclusion that no additional portions of the U.S. mainland were at risk of python invasion. When used with default settings, MaxEnt overfit the realized climate space, identifying models with about 60 parameters, about five times the number of parameters justifiable when optimized on the basis of Akaike's Information Criterion. Conclusions/Significance When used with default settings, MaxEnt may not be an appropriate vehicle for identifying all sites at risk of colonization. Model instability and dearth of protections against overfitting, multi-collinearity, and data dredging may combine with a failure to distinguish fundamental from realized climate envelopes to produce models of limited utility. A priori identification of biologically realistic model structure, combined with computational protections against these

  5. Challenges in Exchanging Medication Information: Identifying Gaps in Clinical Document Exchange and Terminology Standards

    PubMed Central

    Phansalkar, Shobha; Robinson, George; Getty, George; Shalaby, James; Tao, David; Broverman, Carol

    2009-01-01

    The availability of accurate medication history information is invaluable for making sound therapeutic decisions. The Continuity of Care Document (CCD) could serve as a mechanism for exchanging interoperable medication information between EHRs. We evaluate the feasibility of representing a medication and its underlying components in a Healthcare Information Technology Standards Panel (HITSP) compliant CCD. Our evaluation resulted in successfully mapping 94% of medication entries and greater than 92% of medication component mappings to CCD constraints. We identify gaps and provide recommendations for improving the representational adequacy of the Federal Medication Terminology (FMT) to fully represent orderable medication concepts. PMID:20351911

  6. Challenges in exchanging medication information: identifying gaps in clinical document exchange and terminology standards.

    PubMed

    Phansalkar, Shobha; Robinson, George; Getty, George; Shalaby, James; Tao, David; Broverman, Carol

    2009-01-01

    The availability of accurate medication history information is invaluable for making sound therapeutic decisions. The Continuity of Care Document (CCD) could serve as a mechanism for exchanging interoperable medication information between EHRs. We evaluate the feasibility of representing a medication and its underlying components in a Healthcare Information Technology Standards Panel (HITSP) compliant CCD. Our evaluation resulted in successfully mapping 94% of medication entries and greater than 92% of medication component mappings to CCD constraints. We identify gaps and provide recommendations for improving the representational adequacy of the Federal Medication Terminology (FMT) to fully represent orderable medication concepts. PMID:20351911

  7. Challenges of the Presidency.

    ERIC Educational Resources Information Center

    McLean, Sandi, Ed.

    "Challenges of the Presidency" explores the circumstances and forces that affect the college president's leadership in identifying and accomplishing the educational mission of the institution. These four papers examine the external forces of government and population trends as well as the internal pressures from faculty and students, and offer…

  8. Accomplishing structural change: Identifying intermediate indicators of success

    PubMed Central

    Miller, Robin Lin; Reed, Sarah J.; Francisco, Vincent

    2012-01-01

    Coalitions are routinely employed across the United States as a method of mobilizing communities to improve local conditions that impact on citizens’ well-being. Success in achieving specific objectives for environmental or structural community change may not quickly translate into improved population outcomes in the community, posing a dilemma for coalitions that pursue changes that focus on altering community conditions. Considerable effort by communities to plan for and pursue structural change objectives, without evidence of logical and appropriate intermediate markers of success could lead to wasted effort. Yet, the current literature provides little guidance on how coalitions might select intermediate indicators of achievement to judge their progress and the utility of their effort. The current paper explores the strengths and weaknesses of various indicators of intermediate success in creating structural changes among a sample of 13 coalitions organized to prevent exposure to HIV among high-risk adolescents in their local communities. PMID:22875684

  9. Activities and Accomplishments of ICAM

    NASA Technical Reports Server (NTRS)

    Tiwari, S. N.

    1997-01-01

    A brief historical background on establishing the Institute for Computational and Applied Mechanics (ICAM) is presented and basic goals and objectives are discussed. It is emphasized that the goal of the ICAM has been to develop and maintain a self-sustaining center of excellence in computational methods at Old Dominion University (ODU). Information is provided on funding sources and budget disposition, recent activities and accomplishments, list of graduate students supported on the program, and number of students who received graduate degrees (M.S. as well as Ph.D.). Information is also provided on research coordination with various scientists and engineers, and on different reports specifically written for ICAM. ICAM has been supported, in part, by NASA Langley Research Center through Grant NAG-1-363. This report constitutes the final report for ICAM for the period ending December 1996. The grant has been monitored by the University Affairs Officers at NASA Langley.

  10. Know Your Monkey: Identifying Primate Conservation Challenges in an Indigenous Kichwa Community Using an Ethnoprimatological Approach.

    PubMed

    Stafford, Ciara A; Alarcon-Valenzuela, Javiera; Patiño, Javier; Preziosi, Richard F; Sellers, William I

    2016-01-01

    Increasing pressure on tropical forests is continually highlighting the need to find new solutions that mitigate the impact of human populations on biodiversity. However, developing solutions that can tackle the drivers of anthropogenic pressure, or at least take them into account, hinges upon building a good understanding of the culture and perceptions of local people. This study aims to provide an overview of the ethnoprimatology of an indigenous Kichwa community in the Ecuadorian Amazon that maintains a traditional lifestyle but also has good access to markets. We examine whether primates are seen as a distinctive group and their relative importance as sources of bushmeat and as household pets. Pile-sorting exercises revealed that although locals generally group members of the order Primates together, tree-dwelling non-primates including sloths, coatis, kinkajous and tamanduas are also frequently classified as 'monkeys'. The perceived importance of primates to the forest and the community lay more in their potential as bushmeat, and only 1 respondent identified an ecological role for the group in terms of seed dispersal. Gaining a better understanding of local perceptions will allow for better-informed conservation decisions that are more aware of potential impacts and are more likely to gain community support. PMID:27093638

  11. Identifying occurrences of groundwater arsenic in Latin America: a continent-wide problem and challenge

    NASA Astrophysics Data System (ADS)

    Bundschuh, J.; Lopez, D.; Bhattacharya, P.; Cumbal, L.; Litter, M.

    2008-05-01

    in groundwater and related severe health effects, was reported for the first time in 1996 (groundwater: up to 1.32 mg/L). In Ecuador, the occurrence of natural arsenic was recently found in the Papallacta Lake showing arsenic concentrations that vary from 0.104 to 0.360 mg As/L. Arsenic up to 0.136 mg/L was also found in springs that are used as drinking water sources in towns of the Pichincha Province. In the case of El Salvador, high concentrations of arsenic have been found in three lakes: Ilopango, Coatepeque, and Olomega. Ilopango lake (184.9 km2) hosts more than 300,000 inhabitants in its drainage basin, many of them use its water with concentrations of As from 0.15 to 0.77 mg/L. It can be concluded that contamination of ground and surface water by As of geogenic origin is one important environmental problem in Latin America. The As sources are predominantly sediments derived from volcanic rocks, sulfide ore bodies, and volcanic rocks. The solution of this problem is a severe challenge for the Latin American countries during the 21st century.

  12. Identifying Thermally Challenging Landscapes and Time Periods for Wildlife Using Remote Sensing

    NASA Astrophysics Data System (ADS)

    Albright, T. P.; Pidgeon, A.; Radeloff, V.; Wardlow, B.

    2011-12-01

    Recent events and climate model outputs indicate an increase in the occurrence and magnitude of heat waves and other high temperature events in many locations. Temperatures at the land surface may be much higher than air temperatures making this a particularly relevant consideration for animals that nest, forage, or seek refuge at or near the ground. Often associated with heat waves are prolonged and/or rapid onset drought events, which can combine to place stress on vegetation and animals. In order to assess the influence of heat waves and drought on communities of birds, we developed statistical models between avian abundance and species richness data collected by volunteer observers as part of the North American Breeding Bird Survey and a suite of precipitation and temperature metrics. We used station data, gridded standardized precipitation indices, and remotely sensed vegetation indices, and developed an index of accumulated temperature exceedance using time series MODIS land surface temperature (LST) products. Mixed effects models accounting for nuisance factors and temporal autocorrelation revealed that LST was among the strongest predictors of same year and following-year avian abundance. In particular, declines in abundance were largest and most common among ground-nesting birds and long-distance migrants in the US Southwest. In cooler regions, high LST exceedances were sometimes associated with increases in abundance. Because these results do not indicate whether dispersal, reproductive effort, or mortality explain the changes, one area of current research focuses on identifying demographic mechanisms and population consequences of such responses. A second area of active research focuses on using LST data in conjunction with digital elevation models and derivatives and dense networks of ground-level observations to produce physiologically-relevant indicators of thermally stressful conditions for birds and other animals.

  13. Making Out the Invisible: the Challenge of Identifying Blind or Hidden Faults

    NASA Astrophysics Data System (ADS)

    Valensise, G.

    2011-12-01

    lack a brittle surface expression; 2) as a result of 1), improve the completeness of fault compilations and databases; 3) identify the sources of past and future earthquakes in their full 3D extent and not just from their surface expression (if any), thus improving the reliability of ground shaking predictions; 4) as a result of 3), put all faults - both visible and blind - in their hierachical relationships, so that secondary faults can be easily discarded and only major seismogenic sources are accounted for in subsequent seismic hazard calculations. As any modern seismic risk analysis will demonstrate, ground shaking is by far the most important cause of all earthquake-related losses worldwide, and losses caused by shaking-induced phenomena such as landlsides and ground failure largely outpace losses caused by surface faulting (e.g. Bird and Bommer, 2004, Eng Geol, 75, 147-179). These circumstances stress the need for improving the knowledge on the deep geometry of large seismogenic faults - and hence improving the reliability of ground shaking estimates - by resorting to all available geological tools of "geological geodesy". In the presentation I will discuss case-histories from different parts of the world and show the advantages and the limitations of various experimental and analytical approaches.

  14. Changing Climate, Challenging Choices: Identifying and Evaluating Climate Change Adaptation Options for Protected Areas Management in Ontario, Canada

    NASA Astrophysics Data System (ADS)

    Lemieux, Christopher J.; Scott, Daniel J.

    2011-10-01

    Climate change will pose increasingly significant challenges to managers of parks and other forms of protected areas around the world. Over the past two decades, numerous scientific publications have identified potential adaptations, but their suitability from legal, policy, financial, internal capacity, and other management perspectives has not been evaluated for any protected area agency or organization. In this study, a panel of protected area experts applied a Policy Delphi methodology to identify and evaluate climate change adaptation options across the primary management areas of a protected area agency in Canada. The panel identified and evaluated one hundred and sixty five (165) adaptation options for their perceived desirability and feasibility. While the results revealed a high level of agreement with respect to the desirability of adaptation options and a moderate level of capacity pertaining to policy formulation and management direction, a perception of low capacity for implementation in most other program areas was identified. A separate panel of senior park agency decision-makers used a multiple criterion decision-facilitation matrix to further evaluate the institutional feasibility of the 56 most desirable adaptation options identified by the initial expert panel and to prioritize them for consideration in a climate change action plan. Critically, only two of the 56 adaptation options evaluated by senior decision-makers were deemed definitely implementable, due largely to fiscal and internal capacity limitations. These challenges are common to protected area agencies in developed countries and pervade those in developing countries, revealing that limited adaptive capacity represents a substantive barrier to biodiversity conservation and other protected area management objectives in an era of rapid climate change.

  15. Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders

    PubMed Central

    Kopp, Nathan; Climer, Sharlee; Dougherty, Joseph D.

    2015-01-01

    The substantial progress in the last few years toward uncovering genetic causes and risk factors for autism spectrum disorders (ASDs) has opened new experimental avenues for identifying the underlying neurobiological mechanism of the condition. The bounty of genetic findings has led to a variety of data-driven exploratory analyses aimed at deriving new insights about the shared features of these genes. These approaches leverage data from a variety of different sources such as co-expression in transcriptomic studies, protein–protein interaction networks, gene ontologies (GOs) annotations, or multi-level combinations of all of these. Here, we review the recurrent themes emerging from these analyses and highlight some of the challenges going forward. Themes include findings that ASD associated genes discovered by a variety of methods have been shown to contain disproportionate amounts of neurite outgrowth/cytoskeletal, synaptic, and more recently Wnt-related and chromatin modifying genes. Expression studies have highlighted a disproportionate expression of ASD gene sets during mid fetal cortical development, particularly for rare variants, with multiple analyses highlighting the striatum and cortical projection and interneurons as well. While these explorations have highlighted potentially interesting relationships among these ASD-related genes, there are challenges in how to best transition these insights into empirically testable hypotheses. Nonetheless, defining shared molecular or cellular pathology downstream of the diverse genes associated with ASDs could provide the cornerstones needed to build toward broadly applicable therapeutic approaches. PMID:26500678

  16. Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders.

    PubMed

    Kopp, Nathan; Climer, Sharlee; Dougherty, Joseph D

    2015-01-01

    The substantial progress in the last few years toward uncovering genetic causes and risk factors for autism spectrum disorders (ASDs) has opened new experimental avenues for identifying the underlying neurobiological mechanism of the condition. The bounty of genetic findings has led to a variety of data-driven exploratory analyses aimed at deriving new insights about the shared features of these genes. These approaches leverage data from a variety of different sources such as co-expression in transcriptomic studies, protein-protein interaction networks, gene ontologies (GOs) annotations, or multi-level combinations of all of these. Here, we review the recurrent themes emerging from these analyses and highlight some of the challenges going forward. Themes include findings that ASD associated genes discovered by a variety of methods have been shown to contain disproportionate amounts of neurite outgrowth/cytoskeletal, synaptic, and more recently Wnt-related and chromatin modifying genes. Expression studies have highlighted a disproportionate expression of ASD gene sets during mid fetal cortical development, particularly for rare variants, with multiple analyses highlighting the striatum and cortical projection and interneurons as well. While these explorations have highlighted potentially interesting relationships among these ASD-related genes, there are challenges in how to best transition these insights into empirically testable hypotheses. Nonetheless, defining shared molecular or cellular pathology downstream of the diverse genes associated with ASDs could provide the cornerstones needed to build toward broadly applicable therapeutic approaches. PMID:26500678

  17. Expression analysis of immune related genes identified from the coelomocytes of sea cucumber (Apostichopus japonicus) in response to LPS challenge.

    PubMed

    Dong, Ying; Sun, Hongjuan; Zhou, Zunchun; Yang, Aifu; Chen, Zhong; Guan, Xiaoyan; Gao, Shan; Wang, Bai; Jiang, Bei; Jiang, Jingwei

    2014-01-01

    The sea cucumber (Apostichopus japonicus) occupies a basal position during the evolution of deuterostomes and is also an important aquaculture species. In order to identify more immune effectors, transcriptome sequencing of A. japonicus coelomocytes in response to lipopolysaccharide (LPS) challenge was performed using the Illumina HiSeq™ 2000 platform. One hundred and seven differentially expressed genes were selected and divided into four functional categories including pathogen recognition (25 genes), reorganization of cytoskeleton (27 genes), inflammation (41 genes) and apoptosis (14 genes). They were analyzed to elucidate the mechanisms of host-pathogen interactions and downstream signaling transduction. Quantitative real-time polymerase chain reactions (qRT-PCRs) of 10 representative genes validated the accuracy and reliability of RNA sequencing results with the correlation coefficients from 0.88 to 0.98 and p-value <0.05. Expression analysis of immune-related genes after LPS challenge will be useful in understanding the immune response mechanisms of A. japonicus against pathogen invasion and developing strategies for resistant markers selection. PMID:25421239

  18. Expression Analysis of Immune Related Genes Identified from the Coelomocytes of Sea Cucumber (Apostichopus japonicus) in Response to LPS Challenge

    PubMed Central

    Dong, Ying; Sun, Hongjuan; Zhou, Zunchun; Yang, Aifu; Chen, Zhong; Guan, Xiaoyan; Gao, Shan; Wang, Bai; Jiang, Bei; Jiang, Jingwei

    2014-01-01

    The sea cucumber (Apostichopus japonicus) occupies a basal position during the evolution of deuterostomes and is also an important aquaculture species. In order to identify more immune effectors, transcriptome sequencing of A. japonicus coelomocytes in response to lipopolysaccharide (LPS) challenge was performed using the Illumina HiSeq™ 2000 platform. One hundred and seven differentially expressed genes were selected and divided into four functional categories including pathogen recognition (25 genes), reorganization of cytoskeleton (27 genes), inflammation (41 genes) and apoptosis (14 genes). They were analyzed to elucidate the mechanisms of host-pathogen interactions and downstream signaling transduction. Quantitative real-time polymerase chain reactions (qRT-PCRs) of 10 representative genes validated the accuracy and reliability of RNA sequencing results with the correlation coefficients from 0.88 to 0.98 and p-value <0.05. Expression analysis of immune-related genes after LPS challenge will be useful in understanding the immune response mechanisms of A. japonicus against pathogen invasion and developing strategies for resistant markers selection. PMID:25421239

  19. Benefits and Challenges with Applying Unique Molecular Identifiers in Next Generation Sequencing to Detect Low Frequency Mutations

    PubMed Central

    Kou, Ruqin; Lam, Ham; Duan, Hairong; Ye, Li; Jongkam, Narisra; Chen, Weizhi; Zhang, Shifang; Li, Shihong

    2016-01-01

    Indexing individual template molecules with a unique identifier (UID) before PCR and deep sequencing is promising for detecting low frequency mutations, as true mutations could be distinguished from PCR errors or sequencing errors based on consensus among reads sharing same index. In an effort to develop a robust assay to detect from urine low-abundant bladder cancer cells carrying well-documented mutations, we have tested the idea first on a set of mock templates, with wild type and known mutants mixed at defined ratios. We have measured the combined error rate for PCR and Illumina sequencing at each nucleotide position of three exons, and demonstrated the power of a UID in distinguishing and correcting errors. In addition, we have demonstrated that PCR sampling bias, rather than PCR errors, challenges the UID-deep sequencing method in faithfully detecting low frequency mutation. PMID:26752634

  20. Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics

    PubMed Central

    Houldcroft, Charlotte J.; Breuer, Judith

    2015-01-01

    Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts. Different herpesviruses have different cell tropisms, and have been detected in a diverse range of tissues and sample types. Metagenomics—encompassing viromics—analyses the nucleic acid of a tissue or other sample in an unbiased manner, making few or no prior assumptions about which viruses may be present in a sample. This approach has successfully discovered a number of novel herpesviruses. Furthermore, metagenomic analysis can identify herpesviruses with high degrees of sequence divergence from known herpesviruses and does not rely upon culturing large quantities of viral material. Metagenomics has had success in two areas of herpesvirus sequencing: firstly, the discovery of novel exogenous and endogenous herpesviruses in primates, bats and cnidarians; and secondly, in characterizing large areas of the genomes of herpesviruses previously only known from small fragments, revealing unexpected diversity. This review will discuss the successes and challenges of using metagenomics to identify novel herpesviruses, and future directions within the field. PMID:25821447

  1. Challenger

    ERIC Educational Resources Information Center

    Allday, Jonathan

    2002-01-01

    The events that led to the spectacular destruction of the Space Shuttle "Challenger" in 1986 are detailed here. They show how NASA should have heeded engineers' worries over materials problems resulting from a launch in cold weather. Suggestions are made of how pupils could also learn from this tragedy. (Contains 4 figures and 2 footnotes.)

  2. Challenger

    NASA Astrophysics Data System (ADS)

    Allday, Jonathan

    2002-09-01

    The events that led to the spectacular destruction of the Space Shuttle Challenger in 1986 are detailed here. They show how NASA should have heeded engineers' worries over materials problems resulting from a launch in cold weather. Suggestions are made of how pupils could also learn from this tragedy.

  3. Challenges

    ERIC Educational Resources Information Center

    Moore, Thomas R.

    1975-01-01

    Domestic and international challenges facing the National Society for the Prevention of Blindness are discussed; and U.S. and Russian programs in testing and correcting children's vision, developing eye safety programs in agriculture and industry, and disseminating information concerning the detection and treatment of cataracts are compared. (SB)

  4. Household Equipment Research: Past Accomplishments, Challenges for the Future.

    ERIC Educational Resources Information Center

    Lovingood, Rebecca P.; Lytton, Ruth H.

    1984-01-01

    Reviewing household equipment research over 75 years, this study found researchers responding to needs for information on new appliances, energy, and consumer protection. Since 1950 research has increasingly reflected marketers' concerns. Researchers have been hampered by problems of conceptualization, visibility, funding, and a reactive…

  5. Pediatric hypertension: recent trends and accomplishments, future challenges.

    PubMed

    Flynn, Joseph T

    2008-06-01

    Publication of the Fourth Report on high blood pressure (BP) in children and adolescents by the National High BP Education Program (NHBPEP) in 2004 has been followed by a remarkable increase in interest in pediatric hypertension. New data have emerged on the epidemiology of hypertension in the young, the influence of the childhood obesity epidemic on BP, how ambulatory BP monitoring (ABPM) can be used in evaluating elevated BP and the extent of hypertensive target-organ damage in the pediatric age group. Exciting new information on drug treatment of pediatric hypertension has been produced by industry-sponsored clinical trials of antihypertensive medications spurred by the FDA Modernization Act (FDAMA) and successor legislation. Despite these trends, recognition of elevated BP in children and adolescents by primary care providers remains problematic. This article will highlight these and other aspects of pediatric hypertension, hopefully providing a snapshot of where we are in early 2008, and pointing out areas where further work is needed in order to reduce the future burden of adult cardiovascular disease. PMID:18437129

  6. Accreditation of Medical Education in China: Accomplishments and Challenges

    ERIC Educational Resources Information Center

    Wang, Qing

    2014-01-01

    As an external review mechanism, accreditation has played a positive global role in quality assurance and promotion of educational reform. Accreditation systems for medical education have been developed in more than 100 countries including China. In the past decade, Chinese standards for basic medical education have been issued together with…

  7. Transmutation Fuels Campaign FY-09 Accomplishments Report

    SciTech Connect

    Lori Braase

    2009-09-01

    This report summarizes the fiscal year 2009 (FY-08) accomplishments for the Transmutation Fuels Campaign (TFC). The emphasis is on the accomplishments and relevance of the work. Detailed description of the methods used to achieve the highlighted results and the associated support tasks are not included in this report.

  8. Wind Energy Program: Top 10 Program Accomplishments

    SciTech Connect

    2009-01-18

    Brochure on the top accomplishments of the Wind Energy Program, including the development of large wind machines, small machines for the residential market, wind tunnel testing, computer codes for modeling wind systems, high definition wind maps, and successful collaborations.

  9. Accomplishments of Science by the Year 2000

    NASA Technical Reports Server (NTRS)

    Bergman, J.

    1985-01-01

    Current and projected accomplishments in science and technology are examined from a social and political perspective. It is observed that the present level of research and development in the United States is inadequate for many possible advancements to occur.

  10. Lunabotics Mining Competition: Inspiration Through Accomplishment

    NASA Technical Reports Server (NTRS)

    Mueller, Robert P.

    2011-01-01

    NASA's Lunabotics Mining Competition is designed to promote the development of interest in space activities and STEM (Science, Technology, Engineering, and Mathematics) fields. The competition uses excavation, a necessary first step towards extracting resources from the regolith and building bases on the moon. The unique physical properties of lunar regolith and the reduced 1/6th gravity, vacuum environment make excavation a difficult technical challenge. Advances in lunar regolith mining have the potential to significantly contribute to our nation's space vision and NASA space exploration operations. The competition is conducted annually by NASA at the Kennedy Space Center Visitor Complex. The teams that can use telerobotic or autonomous operation to excavate a lunar regolith geotechnical simulant, herein after referred to as Black Point-1 (or BP-1) and score the most points (calculated as an average of two separate 10-minute timed competition attempts) will eam points towards the Joe Kosmo Award for Excellence and the scores will reflect ranking in the on-site mining category of the competition. The minimum excavation requirement is 10.0 kg during each competition attempt and the robotic excavator, referred to as the "Lunabot", must meet all specifications. This paper will review the achievements of the Lunabotics Mining Competition in 2010 and 2011, and present the new rules for 2012. By providing a framework for robotic design and fabrication, which culminates in a live competition event, university students have been able to produce sophisticated lunabots which are tele-operated. Multi-disciplinary teams are encouraged and the extreme sense of accomplishment provides a unique source of inspiration to the participating students, which has been shown to translate into increased interest in STEM careers. Our industrial sponsors (Caterpillar, Newmont Mining, Harris, Honeybee Robotics) have all stated that there is a strong need for skills in the workforce related

  11. What Has the Federal Renewable Fuels Standard Accomplished - A National Perspective (Presentation)

    SciTech Connect

    Schwab, A.

    2013-04-01

    This presentation provides an overview of the nation's biofuels industry accomplishments and a perspective on the challenges and implications of reaching goals set in the Renewable Fuel Standard (RFS).

  12. Identifying the Challenges and Opportunities to Meet the Needs of Children with Speech, Language and Communication Difficulties

    ERIC Educational Resources Information Center

    Dockrell, Julie E.; Howell, Peter

    2015-01-01

    The views of experienced educational practitioners were examined with respect to the terminology used to describe children with speech, language and communication needs (SLCN), associated problems and the impact of speech and language difficulties in the classroom. Results showed that education staff continue to experience challenges with the…

  13. Urban Head Start Teachers' Classroom Interactions with Black Male Preschoolers Identified as "Challenging" or "Externalizing": Opportunities for Teaching Self-Regulation

    ERIC Educational Resources Information Center

    Nunley, Patricia L.

    2012-01-01

    At the earliest grade levels, young Black males, who have been identified by their teachers as "challenging" (in psychological terminology, exhibiting externalizing behavior), have the same disproportionate rate of school suspension and expulsion as their older counterparts (Gilliam, 2005; Lewis, Butler, Bonner, & Joubert, 2010;…

  14. Engineering Accomplishments in the Construction of NCSX

    SciTech Connect

    G. H. Neilson; P.J. Heitzenroeder; B.E. Nelson; W.T. Reiersen; A. Brooks; T.G. Brown; J.H. Chrzanowski; M.J. Cole; F. Dahlgren; T. Dodson; L.E. Dudek; R.A. Ellis; H.M. Fan; P.J. Fogarty; K.D. Freudenberg; P.L. Goranson; J.H. Harris; M.R. Kalish; G. Labik; J.F. Lyon; N. Pomphrey; C.D. Priniski; S. Raftopoulos; D.J. Rej; W.R. Sands; R.T. Simmons; B.E. Stratton; R.L. Strykowsky; M.E. Viola; D.E. Williamson; M.C. Zarnstorff

    2008-09-01

    The National Compact Stellarator Experiment (NCSX) was designed to test a compact, quasiaxisymmetric stellarator configuration. Flexibility and accurate realization of its complex 3D geometry were key requirements affecting the design and construction. While the project was terminated before completing construction, there were significant engineering accomplishments in design, fabrication, and assembly. The design of the stellarator core device was completed. All of the modular coils, toroidal field coils, and vacuum vessel sectors were fabricated. Critical assembly steps were demonstrated. Engineering advances were made in the application of CAD modeling, structural analysis, and accurate fabrication of complex-shaped components and subassemblies. The engineering accomplishments of the project are summarized

  15. Accomplishing Multiple Goals through Community Connections

    ERIC Educational Resources Information Center

    Stone, Jody

    2007-01-01

    With schools being asked to accomplish more and more, it is increasingly important to, whenever possible, address multiple goals in teaching. Educating the whole child dictates that we find ways to ensure our graduates are well-rounded, independent thinkers capable of becoming well-adjusted, contributing adults. Thus community service has become a…

  16. Accomplished Teachers Implementation of Quality Teaching Practices

    ERIC Educational Resources Information Center

    Chen, Weiyun; Hammond-Bennett, Austin; Upton, Ashely; Mason, Steve

    2014-01-01

    The purpose of this study was to describe how accomplished teachers implement the quality of teaching practices in their daily lessons. The participants were four elementary physical education teachers (one male, three female). The data sources consisted of videotape of the teachers teaching 12 lessons, transcription of the taped lessons,…

  17. Acoustics Division recent accomplishments and research plans

    NASA Technical Reports Server (NTRS)

    Clark, L. R.; Morgan, H. G.

    1986-01-01

    The research program currently being implemented by the Acoustics Division of NASA Langley Research Center is described. The scope, focus, and thrusts of the research are discussed and illustrated for each technical area by examples of recent technical accomplishments. Included is a list of publications for the last two calendar years. The organization, staff, and facilities are also briefly described.

  18. Biomass Program 2007 Accomplishments - Full Report

    SciTech Connect

    none,

    2009-10-27

    The Office of Energy Efficiency and Renewable Energy's (EERE’s) Biomass Program works with industry, academia and its national laboratory partners on a balanced portfolio of research in biomass feedstocks and conversion technologies. This document provides Program accomplishments for 2007.

  19. Biomass Program 2007 Accomplishments - Report Introduction

    SciTech Connect

    none,

    2009-10-27

    The Office of Energy Efficiency and Renewable Energy's (EERE’s) Biomass Program works with industry, academia and its national laboratory partners on a balanced portfolio of research in biomass feedstocks and conversion technologies. This document provides the introduction to the 2007 Program Accomplishments Report.

  20. Navajo Health Authority: Accomplishments--Future Goals.

    ERIC Educational Resources Information Center

    Navajo Health Authority, Window Rock, AZ.

    Accomplishments of the Navajo Health Authority (NHA) since it began in 1972 are presented in synopsis form in a report of programs underway at Window Rock and Shiprock, along with NHA goals: to promote development of Navajo Health manpower, preventive medicine, health education, and native healing sciences. After a brief review of executive and…

  1. Chemical Research Projects Office: Functions, accomplishments, and programs

    NASA Technical Reports Server (NTRS)

    Kourtides, D. A.; Parker, J. A.

    1972-01-01

    The purpose, technical accomplishments, and related activities of the Chemical Research Project Group are outlined. Data cover efforts made to: (1) identify chemical research and technology required for solutions to problems of national urgency, synchronous with aeronautics and space effort; (2) conduct basic and applied interdisciplinary research on chemical problems in the areas of macromolecular science and fire research, and (3) provide productive liason with the engineering community and effective transfer of technology to other agencies and industry.

  2. Challenges in identifying Native Hawaiians and Pacific Islanders in population-based cancer registries in the U.S.

    PubMed

    Liu, Lihua; Tanjasiri, Sora Park; Cockburn, Myles

    2011-10-01

    Lack of disaggregated data for Native Hawaiians and Pacific Islanders (NHPIs) in the U.S. has resulted in severe gaps in understanding health disparities and unique health needs of NHPIs. Telephone interviews were conducted with 272 cancer patients identified by a population-based cancer registry. The self-reported NHPIs status was compared with that identified by the registry. Sensitivity, Specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV) were calculated. Alternative NHPIs identification methods were explored. The registry had acceptable sensitivity (89%), specificity (96%) and NPV (99%), but low PPV (62%) in identifying NHPIs. Using additional information on surname and birthplace from the registry improved the identification of NHPIs, but either increased the false positive or decreased the counts of true NHPIs cases. Improved data collection methods and practices in identifying NHPIs in population-based cancer registries are needed and caution in interpreting cancer data for NHPIs is warranted. PMID:20803254

  3. Research on the International Space Station: Understanding Future Potential from Current Accomplishments

    NASA Technical Reports Server (NTRS)

    Robinson, Julie A.

    2007-01-01

    In November 2007, the International Space Station (ISS) will have supported seven years of continuous presence in space, with 15 Expeditions completed. These years have been characterized by the numerous technical challenges of assembly as well as operational and logistical challenges related to the availability of transportation by the Space Shuttle. During this period, an active set of early research objectives have also been accomplished alongside the assembly. This paper will review the research accomplishments on ISS to date, with the objective of drawing insights on the potential of future research following completion of ISS assembly. By the end of Expedition 15, an expected 121 U.S.-managed investigations will have been conducted on ISS, with 91 of these completed. Many of these investigations include multiple scientific objectives, with an estimated total of 334 scientists served. Through February 2007, 101 scientific publications have been identified. Another 184 investigations have been sponsored by ISS international partners, which independently track their scientists served and results publication. Through this survey of U.S. research completed on ISS, three different themes will be addressed: (1) How have constraints on transportation of mass to orbit affected the types of research successfully completed on the ISS to date? What lessons can be learned for increasing the success of ISS as a research platform during the period following the retirement of the Space Shuttle? (2) How have constraints on crew time for research during assembly and the active participation of crewmembers as scientists affected the types of research successfully completed on the ISS to date? What lessons can be learned for optimizing research return following the increase in capacity from 3 to 6 crewmembers (planned for 2009)? What lessons can be learned for optimizing research return after assembly is complete? (3) What do early research results indicate about the various

  4. Development of computational fluid dynamics--habitat suitability (CFD-HSI) models to identify potential passage--Challenge zones for migratory fishes in the Penobscot River

    USGS Publications Warehouse

    Haro, Alexander J.; Dudley, Robert W.; Chelminski, Michael

    2012-01-01

    A two-dimensional computational fluid dynamics-habitat suitability (CFD–HSI) model was developed to identify potential zones of shallow depth and high water velocity that may present passage challenges for five anadromous fish species in the Penobscot River, Maine, upstream from two existing dams and as a result of the proposed future removal of the dams. Potential depth-challenge zones were predicted for larger species at the lowest flow modeled in the dam-removal scenario. Increasing flows under both scenarios increased the number and size of potential velocity-challenge zones, especially for smaller species. This application of the two-dimensional CFD–HSI model demonstrated its capabilities to estimate the potential effects of flow and hydraulic alteration on the passage of migratory fish.

  5. Vocational and Psychosocial Mentoring Functions: Identifying Mentors Who Serve Both [and] Invited Reaction: Challenging Research in Mentoring.

    ERIC Educational Resources Information Center

    Mullen, Ellen J.; Chao, Georgia T.

    1998-01-01

    Mullen's survey of 160 mentors and 140 proteges showed that mentors who initiated relationships, who felt valued by the organization, who were older, or who perceived proteges as competent were most likely to perform both career-related and psychosocial mentoring functions. Chao's response identifies problems in the research. (SK)

  6. Teaching Gifted Children in Today's Preschool and Primary Classrooms: Identifying, Nurturing, and Challenging Children Ages 4-9

    ERIC Educational Resources Information Center

    Smutny, Joan Franklin; Walker, Sally Yahnke; Honeck, Ellen I.

    2016-01-01

    These proven, practical early childhood teaching strategies help teachers identify young gifted children, differentiate curriculum, assess and document students' development, and build partnerships with parents. Chapters focus on early identification, curriculum compacting, social studies, language arts, math and science, cluster grouping,…

  7. Advanced Fuels Campaign FY 2011 Accomplishments Report

    SciTech Connect

    Not Listed

    2011-11-01

    One of the major research and development (R&D) areas under the Fuel Cycle Research and Development (FCRD) program is advanced fuels development. The Advanced Fuels Campaign (AFC) has the responsibility to develop advanced fuel technologies for the Department of Energy (DOE) using a science-based approach focusing on developing a microstructural understanding of nuclear fuels and materials. Accomplishments made during fiscal year (FY 20) 2011 are highlighted in this report, which focuses on completed work and results. The process details leading up to the results are not included; however, the technical contact is provided for each section. The order of the accomplishments in this report is consistent with the AFC work breakdown structure (WBS).

  8. Challenges in Identifying the Foot Motor Region in Patients with Brain Tumor on Routine MRI: Advantages of fMRI

    PubMed Central

    Fisicaro, R.A.; Jiao, R.X.; Stathopoulos, C.; Brennan, N.M. Petrovich; Peck, K.K.; Holodny, A.I.

    2016-01-01

    BACKGROUND AND PURPOSE Accurate localization of the foot/leg motor homunculus is essential because iatrogenic damage can render a patient wheelchair- or bed-bound. We hypothesized the following: 1) Readers would identify the foot motor homunculus <100% of the time on routine MR imaging, 2) neuroradiologists would perform better than nonradiologists, and 3) those with fMRI experience would perform better than those without it. MATERIALSANDMETHODS Thirty-five attending-level raters (24 neuroradiologists, 11 nonradiologists) evaluated 14 brain tumors involving the frontoparietal convexity. Raters were asked to identify the location of the foot motor homunculus and determine whether the tumor involved the foot motor area and/or motor cortex by using anatomic MR imaging. Results were compared on the basis of prior fMRI experience and medical specialty by using Mann-Whitney U test statistics. RESULTS No rater was 100% correct. Raters correctly identified whether the tumor was in the foot motor cortex 77% of the time. Raters with fMRI experience were significantly better than raters without experience at foot motor fMRI centroid predictions (13 ± 6 mm versus 20 ± 13 mm from the foot motor cortex center, P = 2 × 10−6) and arrow placement in the motor gyrus (67% versus 47%, P = 7 × 10−5). Neuroradiologists were significantly better than nonradiologists at foot motor fMRI centroid predictions (15 ± 8 mm versus 20 ± 14 mm, P = .005) and arrow placement in the motor gyrus (61% versus 46%, P = .008). CONCLUSIONS The inability of experienced readers to consistently identify the location of the foot motor homunculus on routine MR imaging argues for using fMRI in the preoperative setting. Experience with fMRI leads to improved accuracy in identifying anatomic structures, even on routine MR imaging. PMID:25882288

  9. Challenges in Identifying and Determining the Impacts of Infection with Pestiviruses on the Herd Health of Free Ranging Cervid Populations.

    PubMed

    Ridpath, Julia F; Neill, John D

    2016-01-01

    Although most commonly associated with the infection of domestic livestock, the replication of pestiviruses, in particular the two species of bovine viral diarrhea virus (BVDV), occurs in a wide range of free ranging cervids including white-tailed deer, mule deer, fallow deer, elk, red deer, roe deer, eland and mousedeer. While virus isolation and serologic analyses indicate that pestiviruses are circulating in these populations, little is known regarding their impact. The lack of regular surveillance programs, challenges in sampling wild populations, and scarcity of tests and vaccines compound the difficulties in detecting and controlling pestivirus infections in wild cervids. Improved detection rests upon the development and validation of tests specific for use with cervid samples and development and validation of tests that reliably detect emerging pestiviruses. Estimation of impact of pestivirus infections on herd health will require the integration of several disciplines including epidemiology, cervid natural history, veterinary medicine, pathology and microbiology. PMID:27379051

  10. Challenges in Identifying and Determining the Impacts of Infection with Pestiviruses on the Herd Health of Free Ranging Cervid Populations

    PubMed Central

    Ridpath, Julia F.; Neill, John D.

    2016-01-01

    Although most commonly associated with the infection of domestic livestock, the replication of pestiviruses, in particular the two species of bovine viral diarrhea virus (BVDV), occurs in a wide range of free ranging cervids including white-tailed deer, mule deer, fallow deer, elk, red deer, roe deer, eland and mousedeer. While virus isolation and serologic analyses indicate that pestiviruses are circulating in these populations, little is known regarding their impact. The lack of regular surveillance programs, challenges in sampling wild populations, and scarcity of tests and vaccines compound the difficulties in detecting and controlling pestivirus infections in wild cervids. Improved detection rests upon the development and validation of tests specific for use with cervid samples and development and validation of tests that reliably detect emerging pestiviruses. Estimation of impact of pestivirus infections on herd health will require the integration of several disciplines including epidemiology, cervid natural history, veterinary medicine, pathology and microbiology. PMID:27379051

  11. Joint Winter Runway Friction Program Accomplishments

    NASA Technical Reports Server (NTRS)

    Yager, Thomas J.; Wambold, James C.; Henry, John J.; Andresen, Arild; Bastian, Matthew

    2002-01-01

    The major program objectives are: (1) harmonize ground vehicle friction measurements to report consistent friction value or index for similar contaminated runway conditions, for example, compacted snow, and (2) establish reliable correlation between ground vehicle friction measurements and aircraft braking performance. Accomplishing these objectives would give airport operators better procedures for evaluating runway friction and maintaining acceptable operating conditions, providing pilots information to base go/no go decisions, and would contribute to reducing traction-related aircraft accidents.

  12. NASA total quality management 1989 accomplishments report

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Described here are the accomplishments of NASA as a result of the use of Total Quality Management (TQM). The principles in practice which led to these process refinements are important cultural elements to any organization's productivity and quality efforts. The categories of TQM discussed here are top management leadership and support, strategic planning, focus on the customer, employee training and recognition, employee empowerment and teamwork, measurement and analysis, and quality assurance.

  13. Enhanced surveillance program FY1998 accomplishments

    SciTech Connect

    Kass, J

    1998-10-01

    This report highlights the accomplishments of the Enhanced Surveillance Program (ESP), the highest-priority research and development effort in stockpile management today. This is volume one of eleven, the unclassified summary of selected program highlights. These highlights fall into the following focus areas: pits, high explosives, organics, dynamics, diagnostics, systems, secondaries, materials-aging models, non-nuclear components, and routine surveillance testing system upgrades. Principal investigators from around the DOE complex contributed to this report.

  14. NASA total quality management 1990 accomplishments report

    NASA Technical Reports Server (NTRS)

    1991-01-01

    NASA's efforts in Total Quality Management are based on continuous improvement and serve as a foundation for NASA's present and future endeavors. Given here are numerous examples of quality strategies that have proven effective and efficient in a time when cost reduction is critical. These accomplishment benefit our Agency and help to achieve our primary goal, keeping American in the forefront of the aerospace industry.

  15. FY005 Accomplishments for Colony Project

    SciTech Connect

    Jones, T; Kale, L; Moreira, J; Mendes, C; Chakravorty, S; Inglett, T; Tauferner, A

    2005-07-05

    The Colony Project is developing operating system and runtime system technology to enable efficient general purpose environments on tens of thousands of processors. To accomplish this, we are investigating memory management techniques, fault management strategies, and parallel resource management schemes. Recent results show promising findings for scalable strategies based on processor virtualization, in-memory checkpointing, and parallel aware modifications to full featured operating systems.

  16. Significant Accomplishments in Science and Technology

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The proceedings of a symposium on significant accomplishments in science and technology are presented. The symposium was held at the Goddard Space Flight Center in December 1973. The subjects discussed are as follows: (1) cometary physics, (2) X-ray and gamma ray astronomy, (3) solar and terrestrial physics, (4) spacecraft technology, (5) Earth Resources Technology Satellite, (6) earth and ocean physics, (6) communications and navigation, (7) mission operations and data systems, and (8) networks systems and operations.

  17. Basic Energy Sciences: Summary of Accomplishments

    DOE R&D Accomplishments Database

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy-related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user'' facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  18. Basic energy sciences: Summary of accomplishments

    NASA Astrophysics Data System (ADS)

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  19. [Challenge to the Development of Molecular Targeted Therapy against a Novel Target Candidate Identified by Antibody Proteomics Technology].

    PubMed

    Nagano, Kazuya

    2016-01-01

    Disease proteomics that systemically analyzes and identifies differentially expressed proteins between healthy and diseased samples is a potentially useful approach for obtaining target proteins for drug development. To date, however, very few target proteins have been identified from this field. A key issue that remains to be resolved is how to correctly identify target proteins from a number of potential candidates. To circumvent this problem, we have developed "antibody proteomics technology" in which a single chain Fv phage antibody library is utilized for proteome analysis. Here, we describe the application of this technology by primarily focusing on Eph receptor A10 (EphA10), a novel breast cancer-related protein that is a promising target for antibody drugs. To establish an effective and safe targeted cancer therapy, it is important that the target is specifically expressed in cancer tissues. Therefore, we attempted to analyze the EphA10 expression profiles. Tissue microarray analysis showed that EphA10 was expressed in all subtypes of breast cancer containing triple negative breast cancer cases. On the other hand, EphA10 was only expressed in testis tissue among 36 kinds of normal tissues. Thus, EphA10 could be a highly cancer-specific protein, making it a promising target for female breast cancer patients. Finally, we examined the anti-tumor effect by anti-EphA10 antibody, aiming for the development of a novel EphA10 targeting therapy. Administration of the antibody showed that tumor volumes were significantly inhibited. Our results suggest that targeting EphA10 in breast cancer cases might be a promising new form of therapy. PMID:26831784

  20. Why Patient Matching Is a Challenge: Research on Master Patient Index (MPI) Data Discrepancies in Key Identifying Fields.

    PubMed

    Just, Beth Haenke; Marc, David; Munns, Megan; Sandefer, Ryan

    2016-01-01

    Patient identification matching problems are a major contributor to data integrity issues within electronic health records. These issues impede the improvement of healthcare quality through health information exchange and care coordination, and contribute to deaths resulting from medical errors. Despite best practices in the area of patient access and medical record management to avoid duplicating patient records, duplicate records continue to be a significant problem in healthcare. This study examined the underlying causes of duplicate records using a multisite data set of 398,939 patient records with confirmed duplicates and analyzed multiple reasons for data discrepancies between those record matches. The field that had the greatest proportion of mismatches (nondefault values) was the middle name, accounting for 58.30 percent of mismatches. The Social Security number was the second most frequent mismatch, occurring in 53.54 percent of the duplicate pairs. The majority of the mismatches in the name fields were the result of misspellings (53.14 percent in first name and 33.62 percent in last name) or swapped last name/first name, first name/middle name, or last name/middle name pairs. The use of more sophisticated technologies is critical to improving patient matching. However, no amount of advanced technology or increased data capture will completely eliminate human errors. Thus, the establishment of policies and procedures (such as standard naming conventions or search routines) for front-end and back-end staff to follow is foundational for the overall data integrity process. Training staff on standard policies and procedures will result in fewer duplicates created on the front end and more accurate duplicate record matching and merging on the back end. Furthermore, monitoring, analyzing trends, and identifying errors that occur are proactive ways to identify data integrity issues. PMID:27134610

  1. Why Patient Matching Is a Challenge: Research on Master Patient Index (MPI) Data Discrepancies in Key Identifying Fields

    PubMed Central

    Just, Beth Haenke; Marc, David; Munns, Megan; Sandefer, Ryan

    2016-01-01

    Patient identification matching problems are a major contributor to data integrity issues within electronic health records. These issues impede the improvement of healthcare quality through health information exchange and care coordination, and contribute to deaths resulting from medical errors. Despite best practices in the area of patient access and medical record management to avoid duplicating patient records, duplicate records continue to be a significant problem in healthcare. This study examined the underlying causes of duplicate records using a multisite data set of 398,939 patient records with confirmed duplicates and analyzed multiple reasons for data discrepancies between those record matches. The field that had the greatest proportion of mismatches (nondefault values) was the middle name, accounting for 58.30 percent of mismatches. The Social Security number was the second most frequent mismatch, occurring in 53.54 percent of the duplicate pairs. The majority of the mismatches in the name fields were the result of misspellings (53.14 percent in first name and 33.62 percent in last name) or swapped last name/first name, first name/middle name, or last name/middle name pairs. The use of more sophisticated technologies is critical to improving patient matching. However, no amount of advanced technology or increased data capture will completely eliminate human errors. Thus, the establishment of policies and procedures (such as standard naming conventions or search routines) for front-end and back-end staff to follow is foundational for the overall data integrity process. Training staff on standard policies and procedures will result in fewer duplicates created on the front end and more accurate duplicate record matching and merging on the back end. Furthermore, monitoring, analyzing trends, and identifying errors that occur are proactive ways to identify data integrity issues. PMID:27134610

  2. Sandia technology engineering and science accomplishments

    SciTech Connect

    Not Available

    1993-03-01

    Sandia is a DOE multiprogram engineering and science laboratory with major facilities at Albuquerque, New Mexico, and Livermore, California, and a test range near Tonapah, Nevada. We have major research and development responsibilities for nuclear weapons, arms control, energy, the environment, economic competitiveness, and other areas of importance to the needs of the nation. Our principal mission is to support national defense policies by ensuring that the nuclear weapon stockpile meets the highest standards of safety, reliability, security, use control, and military performance. Selected unclassified technical activities and accomplishments are reported here. Topics include advanced manufacturing technologies, intelligent machines, computational simulation, sensors and instrumentation, information management, energy and environment, and weapons technology.

  3. Advanced Fuels Campaign FY 2010 Accomplishments Report

    SciTech Connect

    Lori Braase

    2010-12-01

    The Fuel Cycle Research and Development (FCRD) Advanced Fuels Campaign (AFC) Accomplishment Report documents the high-level research and development results achieved in fiscal year 2010. The AFC program has been given responsibility to develop advanced fuel technologies for the Department of Energy (DOE) using a science-based approach focusing on developing a microstructural understanding of nuclear fuels and materials. The science-based approach combines theory, experiments, and multi-scale modeling and simulation aimed at a fundamental understanding of the fuel fabrication processes and fuel and clad performance under irradiation. The scope of the AFC includes evaluation and development of multiple fuel forms to support the three fuel cycle options described in the Sustainable Fuel Cycle Implementation Plan4: Once-Through Cycle, Modified-Open Cycle, and Continuous Recycle. The word “fuel” is used generically to include fuels, targets, and their associated cladding materials. This document includes a brief overview of the management and integration activities; but is primarily focused on the technical accomplishments for FY-10. Each technical section provides a high level overview of the activity, results, technical points of contact, and applicable references.

  4. Health and Environmental Research: summary of accomplishments. Volume 2

    SciTech Connect

    Not Available

    1986-08-01

    This is an account of some of the accomplishments of the health and environmental research program performed in national laboratories, universities, and research institutes. Both direct and indirect societal benefits emerged from the new knowledge provided by the health and environmental research program. In many cases, the private sector took this knowledge and applied it well beyond the mission of supporting the defense and energy needs of the Nation. Industrial and medical applications, for example, have in several instances provided annual savings to society of $100 million or more. The form of this presentation is, in fact, through ''snapshots'' - examples of significant, tangible accomplishments in each of the areas at certain times to illustrate the role and impact of the research program. The program's worth is not necessarily confined to such accomplishments; it extends, rather, to its ability to identify and help solve potential health and environmental problems before they become critical. This anticipatory mission has been pursued with an approach that combines applied problem solving with a commitment to fundamental research that is long-term and high-risk. The narrative of this research program concludes with a perspective of its past and a prospectus on its future.

  5. Health and Environmental Research: Summary of Accomplishments. Volume 2

    DOE R&D Accomplishments Database

    1986-08-01

    This is an account of some of the accomplishments of the health and environmental research program performed in national laboratories, universities, and research institutes. Both direct and indirect societal benefits emerged from the new knowledge provided by the health and environmental research program. In many cases, the private sector took this knowledge and applied it well beyond the mission of supporting the defense and energy needs of the Nation. Industrial and medical applications, for example, have in several instances provided annual savings to society of $100 million or more. The form of this presentation is, in fact, through "snapshots" - examples of significant, tangible accomplishments in each of the areas at certain times to illustrate the role and impact of the research program. The program's worth is not necessarily confined to such accomplishments; it extends, rather, to its ability to identify and help solve potential health and environmental problems before they become critical. This anticipatory mission has been pursued with an approach that combines applied problem solving with a commitment to fundamental research that is long-term and high-risk. The narrative of this research program concludes with a perspective of its past and a prospectus on its future.

  6. When Lightning Strikes Twice: Profoundly Gifted, Profoundly Accomplished.

    PubMed

    Makel, Matthew C; Kell, Harrison J; Lubinski, David; Putallaz, Martha; Benbow, Camilla P

    2016-07-01

    The educational, occupational, and creative accomplishments of the profoundly gifted participants (IQs ⩾ 160) in the Study of Mathematically Precocious Youth (SMPY) are astounding, but are they representative of equally able 12-year-olds? Duke University's Talent Identification Program (TIP) identified 259 young adolescents who were equally gifted. By age 40, their life accomplishments also were extraordinary: Thirty-seven percent had earned doctorates, 7.5% had achieved academic tenure (4.3% at research-intensive universities), and 9% held patents; many were high-level leaders in major organizations. As was the case for the SMPY sample before them, differential ability strengths predicted their contrasting and eventual developmental trajectories-even though essentially all participants possessed both mathematical and verbal reasoning abilities far superior to those of typical Ph.D. recipients. Individuals, even profoundly gifted ones, primarily do what they are best at. Differences in ability patterns, like differences in interests, guide development along different paths, but ability level, coupled with commitment, determines whether and the extent to which noteworthy accomplishments are reached if opportunity presents itself. PMID:27225220

  7. Health and Environmental Research. Summary of Accomplishments

    DOE R&D Accomplishments Database

    1984-04-01

    This is a short account of a 40-year-old health and environmental research program performed in national laboratories, universities, and research institutes. Under the sponsorship of the federal agencies that were consecutively responsible for the national energy mission, this research program has contributed to the understanding of the human health and environmental effects of emergining energy technologies. In so doing, it has also evolved several nuclear techniques for the diagnosis and treatment of human ills. The form of this presentation is through examples of significant, tangible accomplishments in each of these areas at certain times to illustrate the role and impact of the research program. The narrative of this research program concludes with a perspective of its past and a prospectus on its future.

  8. Low Cost Methods to Accomplish Aeronomy Science

    NASA Astrophysics Data System (ADS)

    Swenson, G. R.

    2013-12-01

    Accomplishment of aeronomy science using low cost methods involves a number of innovative considerations. These methods will be discussed. They include making broad use of internet to control and operate distributed sensors. Sensor controls should be simple and most important reliable. Imagers are a common sensor for optical systems and include common computer interfaces and menu driven operations which often don't require special software or engineering development. Small, inexpensive but reliable satellite systems are evolving in the Cubesat community. Effective use of students is invaluable, giving them responsibility to operate instrumentation and to routinely archive the data. Management of students is especially important in the early phase of their training to insure quality performance. These ideas will be elaborated on, and most importantly, the science motive is the most important driver for what is done.

  9. NASA total quality management 1989 accomplishments report

    NASA Technical Reports Server (NTRS)

    Tai, Betty P. (Editor); Stewart, Lynne M. (Editor)

    1990-01-01

    NASA and contractor employees achieved many notable improvements in 1989. The highlights of those improvements, described in this seventh annual Accomplishments Report, demonstrate that the people who support NASA's activities are getting more involved in quality and continuous improvement efforts. Their gains solidly support NASA's and this Nation's goal to remain a leader in space exploration and in world-wide market competition, and, when communicated to others through avenues such as this report, foster improvement efforts across government and industry. The principles in practice which led to these process refinements are important cultural elements to any organization's productivity and quality efforts. The categories in this report reflect NASA principles set forth in the 1980's and are more commonly known today as Total Quality Management (TQM): top management leadership and support; strategic planning; focus on the customer; employee training and recognition; employee empowerment and teamwork; measurement and analysis; and quality assurance.

  10. Health and environmental research. Summary of accomplishments

    SciTech Connect

    Not Available

    1984-04-01

    This is a short account of a 40-year-old health and environmental research program performed in national laboratories, universities, and research institutes. Under the sponsorship of the federal agencies that were consecutively responsible for the national energy mission, this research program has contributed to the understanding of the human health and environmental effects of emergining energy technologies. In so doing, it has also evolved several nuclear techniques for the diagnosis and treatment of human ills. The form of this presentation is through examples of significant, tangible accomplishments in each of these areas at certain times to illustrate the role and impact of the research program. The narrative of this research program concludes with a perspective of its past and a prospectus on its future.

  11. High Speed Research: Propulsion Project Accomplishments

    NASA Technical Reports Server (NTRS)

    Shaw, Robert J.

    1998-01-01

    This past year has been one of great accomplishment for the propulsion element of NASA's High Speed Research (HSR) Program. The HSR Program is a NASA/industry partnership to develop the high-risk/high-payoff airframe and propulsion technologies applicable to a second-generation supersonic commercial transport, or High Speed Civil Transport (HSCT). The propulsion element, which also involves industry partners, is managed by the NASA Lewis Research Center. These technologies will contribute greatly to U.S. industry's ability to make an informed product launch decision for an HSCT vehicle. Specific NASA Lewis accomplishments in 1997 include: 1. Small-scale combustor sector tests conducted in Lewis' Engine Research Building contributed to the evolution of approaches to developing a combustor with ultralow NOx emissions. 2. Components were tested in Lewis' CE-9 facility (in Lewis' Engine Research Building) to assess the performance of candidate ceramic matrix composite (CMC) materials in this realistic combustion environment. Test results were promising, and acceptable levels of structural durability were demonstrated for the ceramic matrix composite material tested. Ceramic matrix composites continue to show great promise for use in HSCT combustor liners. 3. Engine emissions tests in Lewis' Propulsion Systems Laboratory provided insight into other classes of emissions (e.g., particulates and aerosols) which will be important to control in HSCT propulsion system designs. 4. Small-scale nozzle tests conducted in Lewis' Aero-Acoustic Propulsion Laboratory are contributing to the design of a low-noise, high-performance mixer/ejector nozzle configuration for HSCT engines. Over 18,000 hours of durability testing were completed in Lewis' materials laboratories to evaluate superalloy and g-titanium aluminide performance for HSCT nozzle applications. A two-dimensional supersonic inlet concept was tested in Lewis' 10- by 10-Foot Supersonic Wind Tunnel. The extensive database and

  12. Electronically Mentoring to Develop Accomplished Professional Teachers

    ERIC Educational Resources Information Center

    Gareis, Christopher R.; Nussbaum-Beach, Sheryl

    2007-01-01

    With nearly half of all new teachers leaving the classroom within 5 years, schools are faced with the challenge of retaining early-career teachers while simultaneously providing them with the support they need to develop into effective professionals. Mentoring novice teachers by pairing them with experienced teachers in schools is a widely adopted…

  13. Space robotics: Recent accomplishments and opportunities for future research

    NASA Technical Reports Server (NTRS)

    Montgomery, Raymond C.; Buttrill, Carey S.; Dorsey, John T.; Juang, Jer-Nan; Lallman, Frederick J.; Moerder, Daniel D.; Scott, Michael A.; Troutman, Patrick; Williams, Robert L., II

    1992-01-01

    The Langley Guidance, Navigation, and Control Technical Committee (GNCTC) was one of six technical committees created in 1991 by the Chief Scientist, Dr. Michael F. Card. During the kickoff meeting Dr. Card charged the chairmen to: (1) establish a cross-Center committee; (2) support at least one workshop in a selected discipline; and (3) prepare a technical paper on recent accomplishments in the discipline and on opportunities for future research. The Guidance, Navigation, and Control Committee was formed and selected for focus on the discipline of Space robotics. This report is a summary of the committee's assessment of recent accomplishments and opportunities for future research. The report is organized as follows. First is an overview of the data sources used by the committee. Next is a description of technical needs identified by the committee followed by recent accomplishments. Opportunities for future research ends the main body of the report. It includes the primary recommendation of the committee that NASA establish a national space facility for the development of space automation and robotics, one element of which is a telerobotic research platform in space. References 1 and 2 are the proceedings of two workshops sponsored by the committee during its June 1991, through May 1992 term. The focus of the committee for the June 1992 - May 1993 term will be to further define to the recommended platform in space and to add an additional discipline which includes aircraft related GN&C issues. To the latter end members performing aircraft related research will be added to the committee. (A preliminary assessment of future opportunities in aircraft-related GN&C research has been included as appendix A.)

  14. Research Progress and Accomplishments on ISS

    NASA Technical Reports Server (NTRS)

    Roe, Lesa B.; Uri, John J.

    2002-01-01

    The first research payloads reached the International Space Station (ISS) more than two years ago, with research operating continuously since March 2001. Seven research racks are currently on-orbit, with three more arriving soon to expand science capabilities. Through the first five expeditions, 60 unique NASA-managed investigations from 11 nations have been supported, many continuing into later missions. More than 90,000 experiment hours have been completed, and more than 1,000 hours of crew time have been dedicated to research, numbers that grow daily. The multidisciplinary program includes research in life sciences, physical sciences, biotechnology, Earth sciences, technology demonstrations as well as commercial endeavors and educational activities. The Payload Operations and Integration Center monitors the onboard activities around the clock, working with numerous Principal Investigators and Payload Developers at their remote sites. Future years will see expansion of the station with research modules provided by the European Space Agency and Japan, which will be outfitted with additional research racks. The first research payloads arrived at ISS more than two years ago, and continuous science has been ongoing for more than one and a half years. During this time, the research capabilities have been tremendously increased, even as assembly of the overall platform continues. Despite significant challenges along the way, ISS continues to successfully support a large number of investigations in a variety of research disciplines. The results of some of the early investigations are reaching the publication stage. The near future looms with new challenges, but experience to date and dedicated efforts give reason to be optimistic that the challenges will be overcome and that new and greater successes will be added to past ones.

  15. Comprehensive cancer control: progress and accomplishments.

    PubMed

    Rochester, Phyllis W; Townsend, Julie S; Given, Leslie; Krebill, Hope; Balderrama, Sandra; Vinson, Cynthia

    2010-12-01

    The potential for Comprehensive Cancer Control (CCC) across the nation has been realized in the last decade with 69 Coalitions developing and implementing CCC plans. Many partners at all levels--national, state, jurisdictional, tribal and communities--have contributed to this success. This article details the contribution of these partners across these various levels, with a selection of the many activities contributing to this success. Consequently the cancer burden, although still of major importance, continues to be addressed in significant ways. Although there are future challenges, CCC coalitions continue to play an important role in addressing the cancer burden. PMID:21069448

  16. Function-Based Intervention: Accomplishments and Future Directions

    ERIC Educational Resources Information Center

    Umbreit, John; Ferro, Jolenea B.

    2015-01-01

    The field of function-based intervention has changed the way behavioral support is provided to students with challenging behavior. Our goal is to identify and describe some key findings and practices that have facilitated this progress. We also pinpoint some areas for future research that are likely to contribute to further progress.

  17. Back to the basics: Identifying and addressing underlying challenges in achieving high quality and relevant health statistics for indigenous populations in Canada

    PubMed Central

    Smylie, Janet; Firestone, Michelle

    2015-01-01

    Canada is known internationally for excellence in both the quality and public policy relevance of its health and social statistics. There is a double standard however with respect to the relevance and quality of statistics for Indigenous populations in Canada. Indigenous specific health and social statistics gathering is informed by unique ethical, rights-based, policy and practice imperatives regarding the need for Indigenous participation and leadership in Indigenous data processes throughout the spectrum of indicator development, data collection, management, analysis and use. We demonstrate how current Indigenous data quality challenges including misclassification errors and non-response bias systematically contribute to a significant underestimate of inequities in health determinants, health status, and health care access between Indigenous and non-Indigenous people in Canada. The major quality challenge underlying these errors and biases is the lack of Indigenous specific identifiers that are consistent and relevant in major health and social data sources. The recent removal of an Indigenous identity question from the Canadian census has resulted in further deterioration of an already suboptimal system. A revision of core health data sources to include relevant, consistent, and inclusive Indigenous self-identification is urgently required. These changes need to be carried out in partnership with Indigenous peoples and their representative and governing organizations. PMID:26793283

  18. Light Water Reactor Sustainability Accomplishments Report

    SciTech Connect

    McCarthy, Kathryn A.

    2015-02-01

    Welcome to the 2014 Light Water Reactor Sustainability (LWRS) Program Accomplishments Report, covering research and development highlights from 2014. The LWRS Program is a U.S. Department of Energy research and development program to inform and support the long-term operation of our nation’s commercial nuclear power plants. The research uses the unique facilities and capabilities at the Department of Energy national laboratories in collaboration with industry, academia, and international partners. Extending the operating lifetimes of current plants is essential to supporting our nation’s base load energy infrastructure, as well as reaching the Administration’s goal of reducing greenhouse gas emissions to 80% below 1990 levels by the year 2050. The purpose of the LWRS Program is to provide technical results for plant owners to make informed decisions on long-term operation and subsequent license renewal, reducing the uncertainty, and therefore the risk, associated with those decisions. In January 2013, 104 nuclear power plants operated in 31 states. However, since then, five plants have been shut down (several due to economic reasons), with additional shutdowns under consideration. The LWRS Program aims to minimize the number of plants that are shut down, with R&D that supports long-term operation both directly (via data that is needed for subsequent license renewal), as well indirectly (with models and technology that provide economic benefits). The LWRS Program continues to work closely with the Electric Power Research Institute (EPRI) to ensure that the body of information needed to support SLR decisions and actions is available in a timely manner. This report covers selected highlights from the three research pathways in the LWRS Program: Materials Aging and Degradation, Risk-Informed Safety Margin Characterization, and Advanced Instrumentation, Information, and Control Systems Technologies, as well as a look-ahead at planned activities for 2015. If you

  19. Some History and Accomplishments of the IUSS

    NASA Astrophysics Data System (ADS)

    Brevik, Eric C.; Hartemink, Alfred E.

    2013-04-01

    Urban Soils) and three standing committees (Committee on awards and prizes, Committee on budget and finances, and Committee on statutes and byelaws). Membership in ISSS/IUSS increased from around 550 after WWII to over 60,000 today. The IUSS also provides Honorary Membership to soil scientists who have significant accomplishments in the field; to date 87 soil scientists have been so recognized from all over the globe. The IUSS is the most important global link to the world's leading soil science and soil scientists.

  20. Accomplishing Lessons in Postcolonial Classrooms: Comparative Perspectives from Botswana and Brunei Darussalam

    ERIC Educational Resources Information Center

    Arthur, Jo; Martin, Peter

    2006-01-01

    Drawing on observations and audio-recordings of classroom language use in two postcolonial societies, the Republic of Botswana in Africa and the Sultanate of Brunei Darussalam in south-east Asia, this study seeks to explore how teachers and pupils face the challenge of accomplishing teaching and learning using a language which is not their own. In…

  1. The Accomplishments of Disabled Women's Advocacy Organizations and Their Future in Korea

    ERIC Educational Resources Information Center

    Kim, Kyung Mee

    2010-01-01

    Since the late 1990s disabled women's advocacy organizations have fought against oppression and have made great strides in Korea. This paper aims to describe the accomplishments, challenges and future directions of disabled women's advocacy organizations in Korea. A qualitative design was employed to explore disabled women's perspectives.…

  2. Advanced Fuels Campaign FY 2014 Accomplishments Report

    SciTech Connect

    Lori Braase; W. Edgar May

    2014-10-01

    The overall goal of ATF development is to identify alternative fuel system technologies to further enhance the safety, competitiveness, and economics of commercial nuclear power. The complex multiphysics behavior of LWR nuclear fuel in the integrated reactor system makes defining specific material or design improvements difficult; as such, establishing desirable performance attributes is critical in guiding the design and development of fuels and cladding with enhanced accident tolerance.

  3. Lunabotics Mining Competition: Inspiration through Accomplishment

    NASA Technical Reports Server (NTRS)

    Mueller, Robert P.

    2012-01-01

    Space Mining for resources such as water ice, and regolith, which contain many elements in the form of metals, minerals, volatiles and other compounds, is a necessary step in Space Resource Utilization. One of the primary goals is to extract propellants from the regolith such as oxygen and hydrogen which could then be used for in-space transportation. In addition, the space mining system can be used for various construction tasks that can benefit human and robotic exploration as well as scientific investigations based on the exposed topography. The National Aeronautics & Space Administration (NASA) Lunabotics Mining Competition is a university-level competition designed to engage and retain students in science, technology, engineering and mathematics (STEM). NASA will directly benefit from the competition by encouraging the development of innovative lunar excavation concepts from universities which may result in clever ideas and solutions which could be applied to an actual lunar excavation device or payload. The challenge is for students to design and build a remote controlled or autonomous excavator, called a lunabot, that can collect and deposit a minimum of 10 kilograms of lunar simulant within 15 minutes. The complexities of the challenge include the abrasive characteristics of the lunar simulant, the weight and size limitations of the lunabot, and the ability to control the lunabot from a remote control center or operate autonomously. This paper will present an update of the results and lessons learned during the first and second annual Lunabotics Mining Competitions held in May 2010 and May 2011. It will also preview the 2012 competition with a review of the revised rules. In 2010,22 United States (US) universities competed, and in May 2011 the competition was opened to international participation. In 2011, 36 teams actually competed from 26 USA states and 4 foreign countries (India, Bangladesh, Colombia and Canada). This combined total directly inspired an

  4. “Members of the Same Club”: Challenges and Decisions Faced by US IRBs in Identifying and Managing Conflicts of Interest

    PubMed Central

    Klitzman, Robert

    2011-01-01

    Conflicts of interest (COIs) in research have received increasing attention, but many questions arise about how Institutional Review Boards (IRBs) view and approach these. Methods I conducted in-depth interviews of 2 hours each with 46 US IRB chairs, administrators, and members, exploring COI and other issues related to research integrity. I contacted leaders of 60 IRBs (every fourth one among the top 240 institutions by NIH funding), and interviewed IRB leaders from 34 of these institutions (response rate = 55%). Data were analyzed using standard qualitative methods, informed by Grounded Theory. Results IRBs confront financial and non-financial COIs of PIs, institutions, and IRBs themselves. IRB members may seek to help, or compete with, principal investigators (PIs). Non-financial COI also often appear to be “indirect financial” conflicts based on gain (or loss) not to oneself, but to one's colleagues or larger institution. IRBs faced challenges identifying and managing these COI, and often felt that they could be more effective. IRBs' management of their own potential COI vary, and conflicted members may observe, participate, and/or vote in discussions. Individual IRB members frequently judge for themselves whether to recuse themselves. Challenges arise in addressing these issues, since institutions and PIs need funding, financial information is considered confidential, and COI can be unconscious. Conclusions This study, the first to explore qualitatively how IRBs confront COIs and probe how IRBs confront non-financial COIs, suggests that IRBs face several types of financial and non-financial COIs, involving themselves, PIs, and institutions, and respond varyingly. These data have critical implications for practice and policy. Disclosure of indirect and non-financial COIs to subjects may not be feasible, partly since IRBs, not PIs, are conflicted. Needs exist to consider guidelines and clarifications concerning when and how, in protocol reviews, IRB

  5. NIRPS - Solutions Facilitator Team Overview and Accomplishments

    NASA Technical Reports Server (NTRS)

    Brown, Thomas M., III; Childress, Rhonda

    2013-01-01

    National Institute for Rocket Propulsion Systems (NIRPS) purpose is to help preserve and align government and private rocket propulsion capabilities to meet present and future US commercial, civil, and defense needs, while providing authoritative insight and recommendations to National decisional authorities. Stewardship: Monitor and analyze the state of the industry in order to formulate and recommend National Policy options and strategies that promote a healthy industrial base and ensure best-value for the American taxpayer. Technology: Identify technology needs and recommend technology insertions by leading roadmap assessments and actively participating in program formulation activities. Solutions Facilitator/Provider: Maintain relationships and awareness across the Government, industry and academia, to align available capacity with emerging demand.

  6. IMHEX fuel cell repeat component manufacturing continuous improvement accomplishments

    SciTech Connect

    Jakaitis, L.A.; Petraglia, V.J.; Bryson, E.S.

    1996-12-31

    M-C Power is taking a power generation technology that has been proven in the laboratory and is making it a commercially competitive product. There are many areas in which this technology required scale up and refinement to reach the market entry goals for the IMHEX{reg_sign} molten carbonate fuel cell power plant. One of the primary areas that needed to be addressed was the manufacturing of the fuel cell stack. Up to this point, the fuel cell stack and associated components were virtually hand made for each system to be tested. M-C Power has now continuously manufactured the repeat components for three 250 kW stacks. M-C Power`s manufacturing strategy integrated both evolutionary and revolutionary improvements into its comprehensive commercialization effort. M-C Power`s objectives were to analyze and continuously improve stack component manufacturing and assembly techniques consistent with established specifications and commercial scale production requirements. Evolutionary improvements are those which naturally occur as the production rates are increased and experience is gained. Examples of evolutionary (learning curve) improvements included reducing scrap rates and decreasing raw material costs by buying in large quantities. Revolutionary improvements result in significant design and process changes to meet cost and performance requirements of the market entry system. Revolutionary changes often involve identifying new methods and developing designs to accommodate the new process. Based upon our accomplishments, M-C Power was able to reduce the cost of continuously manufactured fuel cell repeat components from the first to third 250 kW stack by 63%. This paper documents the continuous improvement accomplishments realized by M-C Power during IMHEX{reg_sign} fuel cell repeat component manufacturing.

  7. The Vasimr Engine: Project Status and Recent Accomplishments

    NASA Technical Reports Server (NTRS)

    ChangDiaz, Franklin R.; Squire, Jared P.; Bering, Edgar A., III; Baitty, F. Wally; Goulding, Richard H.; Bengtson, Roger D.

    2004-01-01

    The development of the Variable Specific Impulse Magnetoplasma Rocket (VASIMR) was initiated in the late 1970s to address a critical requirement for fast, high-power interplanetary space transportation. While not being a fusion rocket, it nevertheless borrows heavily from that technology and takes advantage of the natural topology of open-ended magnetic systems. In addition to its high power density and high exhaust velocity, VASIMR is capable of "constant power throttling" a feature, which allows in-flight mission-optimization of thrust and specific impulse to enhance performance and reduce trip time. A NASA-led, research team, involving industry, academia and government facilities is pursuing the development of this concept in the United States. The technology can be validated, in the near term, in venues such as the International Space Station, where it can also serve as both a drag compensation device and a plasma contactor for the orbital facility. Other near-Earth applications in the commercial and scientific satellite sectors are also envisioned. This presentation covers the evolution of the VASIMR concept to its present status, as well as recent accomplishments in our understanding of the physics. Approaches and collaborative programs addressing the major technical challenges will also be presented.

  8. Space directorate research and technology accomplishments for FY 1988

    NASA Technical Reports Server (NTRS)

    Avery, Don E. (Compiler)

    1989-01-01

    The major accomplishments and test highlights for FY 1988 that occurred in the Space Dirctorate are given. Accomplishments and test highlights are presented by Division and Branch. The presented information will be useful in program coordination with government organizations, universities, and industry in areas of mutual interest.

  9. Sex and Ethnic-Group Differences on Accomplishments Measures.

    ERIC Educational Resources Information Center

    Stricker, Lawrence J.; Rock, Donald A.; Bennett, Randy Elliot

    2001-01-01

    Studied sex and ethnic group differences on 6 scales that measure accomplishments for 739 male and 1,746 female graduate school applicants. With the exception of the scale measuring mechanical accomplishment, men and women did not differ in performance, and ethnic groups did not differ on any scale. (SLD)

  10. Accomplishments in 2008 in the Management of Localized Pancreatic Cancer

    PubMed Central

    O’Reilly, Eileen M.; Lutz, Manfred P.; Neuhaus, Peter

    2009-01-01

    SUMMARY Overview of the DiseaseIncidenceRisk FactorsPrognostic or Predictive FactorsCurrent General Therapy StandardsAccomplishments During the YearTherapyBiomarkersBasic ScienceWhat Needs to Be Done?Applications of the AccomplishmentsControversies and DisagreementsFuture DirectionsComments on ResearchObstacles to Progress PMID:20011563

  11. Space directorate research and technology accomplishments for fiscal year 1987

    NASA Technical Reports Server (NTRS)

    Avery, Don E.

    1988-01-01

    The major accomplishments and test highlights of the Space Directorate of NASA Langley Research Center for FY87 are presented. Accomplishments and test highlights are listed by Division and Branch. This information should be useful in coordinating programs with government organizations, universities, and industry in areas of mutual interest.

  12. Gender-Role Orientation, Creative Accomplishments and Cognitive Styles.

    ERIC Educational Resources Information Center

    Hittner, James B.; Daniels, Jennifer R.

    2002-01-01

    This study examined the association of gender-role orientation to creative accomplishments and cognitive styles in 127 college students. Results indicated that the gender role orientation of instrumentality was positively associated with creative accomplishments in the business venture domain and that androgynous, versus non-androgynous,…

  13. Fort Collins Science Center: Fiscal Year 2007 Accomplishments

    USGS Publications Warehouse

    Wilson, J.T.

    2008-01-01

    In Fiscal Year 2007 (FY07), the U.S. Geological Survey (USGS) Fort Collins Science Center (FORT) continued research vital to U.S. Department of the Interior science and management needs and associated USGS programmatic goals. FORT work also supported the science needs of other government agencies as well as private cooperators. Specifically, FORT scientific research and technical assistance focused on client and partner needs and goals in the areas of biological information management, fisheries and aquatic systems, invasive species, status and trends of biological resources, terrestrial ecosystems, and wildlife resources. In addition, FORT's 5-year strategic plan was refined to incorporate focus areas identified in the USGS strategic science plan, including ecosystem-landscape analysis, global climate change, and energy and mineral resource development. As a consequence, several science projects initiated in FY07 were either entirely new research dor amplifications of existing work. Highlights of FORT project accomplishments are described below under the USGS science program with which each task is most closely associated. The work of FORT's 6 branches (Aquatic Systems and Technology Applications, Ecosystem Dynamics, Information Science, Invasive Species Science, Policy Analysis and Science Assistance, and Species and Habitats of Federal Interest) often involves major partnerships with other agencies or cooperation with other USGS disciplines (Geology, Geography, Water Resources) and the Geospatial Information Office.

  14. EarthScope Education and Outreach: Accomplishments and Emerging Opportunities

    NASA Astrophysics Data System (ADS)

    Robinson, S.; Ellins, K. K.; Semken, S. C.; Arrowsmith, R.

    2014-12-01

    EarthScope's Education and Outreach (E&O) program aims to increase public awareness of Earth science and enhance geoscience education at the K-12 and college level. The program is distinctive among major geoscience programs in two ways. First, planning for education and public engagement occurred in tandem with planning for the science mission. Second, the NSF EarthScope program includes funding support for education and outreach. In this presentation, we highlight key examples of the program's accomplishments and identify emerging E&O opportunities. E&O efforts have been collaboratively led by the EarthScope National Office (ESNO), IRIS, UNAVCO, the EarthScope Education and Outreach Subcommittee (EEOSC) and PI-driven EarthScope projects. Efforts by the EEOSC, guided by an EarthScope Education and Outreach Implementation Plan that is periodically updated, focus EarthScope E&O. EarthScope demonstrated early success in engaging undergraduate students (and teachers) in its mission through their involvement in siting USArray across the contiguous U.S. Funded E&O programs such as TOTLE, Illinois EarthScope, CEETEP (for K-12), InTeGrate and GETSI (for undergraduates) foster use of freely available EarthScope data and research findings. The Next Generation Science Standards, which stress science and engineering practices, offer an opportunity for alignment with existing EarthScope K-12 educational resources, and the EEOSC recommends focusing efforts on this task. The EEOSC recognizes the rapidly growing use of mobile smart devices by the public and in formal classrooms, which bring new opportunities to connect with the public and students. This will capitalize on EarthScope's already prominent social media presence, an effort that developed to accomplish one of the primary goals of the EarthScope E&O Implementation Plan to "Create a high-profile public identity for EarthScope" and to "Promote science literacy and understanding of EarthScope among all audiences through

  15. Technical Report of Accomplishments of the Weatherization Leveraging Partnership Project

    SciTech Connect

    Economic Opportunity Studies

    2007-09-30

    The Weatherization Leveraging Partnership Project was established to provide three types of technical assistance support to W.A.P. network organizations seeking to achieve the Weatherization Plus goal of expanding their non-federal resources. It provided: (1) Analysis that profiled W.A.P.-eligible household energy characteristics and finances for all in determining efficiency investment targets and goals; (2) Detailed information on leveraged partnerships linked from many sources and created a website with finding aids to meet the needs the network identified. There are five major market segments with related, but different, technical assistance needs; (3) Direct, sustained assistance in preparing strategies, analyses, and communications for a limited set of local network initiatives that were in early stages of initiating or changing their resource expansion strategies. The Project identified trends in the challenges that weatherizers initiatives encountered; it designed materials and tools, including the dynamic www.weatherizationplus.org website, to meet the continuing and the emerging needs.

  16. Idaho National Laboratory Mission Accomplishments, Fiscal Year 2015

    SciTech Connect

    Allen, Todd Randall; Wright, Virginia Latta

    2015-09-01

    A summary of mission accomplishments for the research organizations at the Idaho National Laboratory for FY 2015. Areas include Nuclear Energy, National and Homeland Security, Science and Technology Addressing Broad DOE Missions; Collaborations; and Stewardship and Operation of Research Facilities.

  17. Enhanced surveillance program FY97 accomplishments. Progress report

    SciTech Connect

    Mauzy, A.; Laake, B.

    1997-10-01

    This annual report is one volume of the Enhanced Surveillance Program (ESP) FY97 Accomplishments. The complete accomplishments report consists of 11 volumes. Volume 1 includes an ESP overview and a summary of selected unclassified FY97 program highlights. Volume 1 specifically targets a general audience, reflecting about half of the tasks conducted in FY97 and emphasizing key program accomplishments and contributions. The remaining volumes of the accomplishments report are classified, organized by program focus area, and present in technical detail the progress achieved in each of the 104 FY97 program tasks. Focus areas are as follows: pits; high explosives; organics; dynamics; diagnostics; systems; secondaries; nonnuclear materials; nonnuclear components; and Surveillance Test Program upgrades.

  18. Process development accomplishments: Waste and hazard minimization, FY 1991

    SciTech Connect

    Homan, D.A.

    1991-11-04

    This report summarizes significant technical accomplishments of the Mound Waste and Hazard Minimization Program for FY 1991. The accomplishments are in one of eight major areas: environmentally responsive cleaning program; nonhalogenated solvent trials; substitutes for volatile organic compounds; hazardous material exposure minimization; nonhazardous plating development; explosive processing waste reduction; tritium capture without conversion to water; and robotic assembly. Program costs have been higher than planned.

  19. Capitalizing on Social and Transactional Learning to Challenge First-Grade Readers

    ERIC Educational Resources Information Center

    Meyer, Amanda; Schendel, Roland K.

    2014-01-01

    A classroom teacher capitalizes on social learning and reader response theories to challenge her accelerated first-grade readers by implementing literature circles. The aim of this action research was to identify a clear view of "how" to use literature circles with first-graders and "what" might be accomplished. Three…

  20. The 1986-87 NASA space/gravitational biology accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1987-01-01

    This report consists of individual technical summaries of research projects of NASA's Space/Gravitational Biology program, for research conducted during the period January 1986 to April 1987. This program utilizes the unique characteristics of the space environment, particularly microgravity, as a tool to advance knowledge in the biological sciences; understanding how gravity has shaped and affected life on Earth; and understanding how the space environment affects both plant and animal species. The summaries for each project include a description of the research, a list of accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  1. The 1988-1989 NASA Space/Gravitational Biology Accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1990-01-01

    This report consists of individual technical summaries of research projects of NASA's space/gravitational biology program, for research conducted during the period May 1988 to April 1989. This program is concerned with using the unique characteristics of the space environment, particularly microgravity, as a tool to advance knowledge in the biological sciences; understanding how gravity has shaped and affected life on Earth; and understanding how the space environment affects both plant and animal species. The summaries for each project include a description of the research, a list of the accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  2. The 1989-1990 NASA space biology accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1991-01-01

    Individual technical summaries of research projects on NASA's Space Biology Program for research conducted during the period May 1989 to April 1990 are presented. This program is concerned with using the unique characteristics of the space environment, particularly microgravity, as a tool to advance the following: (1) knowledge in the biological sciences; (2) understanding of how gravity has shaped and affected life on the Earth; and (3) understanding of how the space environment affects both plants and animals. The summaries for each project include a description of the research, a list of accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  3. The 1985-86 NASA space/gravitational biology accomplishments

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Individual Technical summaries of research projects of NASA's Space/Gravitational Biology Program are presented. This Program is concerned with using the unique characteristics of the space environment, particularly microgravity, as a tool to advance knowledge in the biological sciences; understanding how gravity has shaped and affected life on Earth; and understanding how the space environment affects both plant and animal species. The summaries for each project include a description of the research, a listing of the accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  4. The 1987-1988 NASA space/gravitational biology accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1988-01-01

    Individual technical summaries of research projects of the NASA Space/Gravitational Biology Program, for research conducted during the period January 1987 to April 1988 are presented. This Program is concerned with using the characteristics of the space environment, particularly microgravity, as a tool to advance knowledge in the biological sciences; understanding how gravity has shaped and affected life on earth; and understanding how the space environment affects both plant and animal species. The summaries for each project include a description of the research, a list of the accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  5. Accomplishing Mars exploration goals by returning a simple "locality" sample

    NASA Astrophysics Data System (ADS)

    McKay, G.; Draper, D.; Bogard, D.; Agee, C.; Ming, D.; Jones, J.

    A major stumbling block to a Mars sample return (MSR) mission is cost. This problem is greatly exacerbated by using elaborate rovers, sophisticated on-board instruments, and complex sample selection techniques to maximize diversity. We argue that many key science goals of the Mars Exploration Program may be accomplished by returning a simple "locality" sample from a well-chosen landing site. Such a sample , collected by a simple scoop, would consist of local regolith containing soil, windblown fines, and lithic fragments (plus Martian atmosphere). Even the simplest sample return mission could revolutionize our understanding of Mars, without the need for expensive rovers or sophisticated on-board instruments. We expect that by the time a MSR mission could be flown, information from the Mars Odyssey, Mars Express, 2003 Mars Exploration Rovers, and 2005 Mars Reconnaissance Orbiter will be sufficient to choose a good landing site. Returned samples of Martian regolith have the potential to answer key questions of fundamental importance to the Mars Exploration Program: The search for life; the role and history of water and other volatiles; interpreting remotely-sensed spectral data; and understanding the planet as a system. A locality sample can further the search for life by identifying trace organics, biogenic elements and their isotopic compositions, evidence for water such as hydrous minerals or cements, the Martian soil oxidant, and trace biomarkers. Learning the nature and timing of atmosphere-soil-rock interactions will improve understanding of the role and history of water. An atmosphere sample will reveal fundamental information about current atmospheric processes. Information about the mineralogy and lithology of sample materials, the extent of impact gardening, and the nature of dust coatings and alteration rinds will provide much-needed ground truth for interpreting remotely-sensed data, including Mars Pathfinder. Basic planetology questions that might be

  6. 5 CFR 720.305 - Agency accomplishment reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Agency accomplishment reports. 720.305 Section 720.305 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) AFFIRMATIVE EMPLOYMENT PROGRAMS Disabled Veterans Affirmative Action Program §...

  7. 5 CFR 720.305 - Agency accomplishment reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Agency accomplishment reports. 720.305 Section 720.305 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) AFFIRMATIVE EMPLOYMENT PROGRAMS Disabled Veterans Affirmative Action Program §...

  8. FAMILY GOALS AND SOME FACTORS ASSOCIATED WITH THEIR ACCOMPLISHMENT.

    ERIC Educational Resources Information Center

    JOHNSTON, RUPERT BERNARD

    GOALS OF FARM FAMILIES WERE ANALYZED AND FACTORS ASSOCIATED WITH THEIR ACCOMPLISHMENT STUDIED. DATA ON FARM GOALS, FARM AND HOME RESOURCES, AND INCOME WERE OBTAINED FROM 112 FAMILIES IN 18 MISSISSIPPI COUNTIES, IN WHICH THERE WERE THREE DIFFERENT COUNTY EXTENSION STAFFING PLANS. GOALS WERE CLASSIFIED IN GOUPS SUCH AS HOME AND GROUNDS, HOME…

  9. 2014 Survey of States: Initiatives, Trends, and Accomplishments

    ERIC Educational Resources Information Center

    Shyyan, Vitaliy; Lazarus, Sheryl S.; Thurlow, Martha L.

    2015-01-01

    This report summarizes the fourteenth survey of states by the National Center on Educational Outcomes (NCEO) at the University of Minnesota. Results are presented for the 50 regular states and eight of the 11 unique states. The purpose of this report is to provide a snapshot of the new initiatives, trends, accomplishments, and emerging issues…

  10. Women in History--Abigail Adams: Life, Accomplishments, and Ideas

    ERIC Educational Resources Information Center

    Kenan, Sharon K.

    2008-01-01

    This article profiles the life, accomplishments, and ideas of Abigail Adams. Born in 1944, Adams lacked a formal education, but she more than made up for that shortcoming with her love of reading, especially literature, and her interests in politics and events surrounding the young colonies. Adams was supportive of the advancement of women. She…

  11. UPPER SNAKE RIVER PRIORITY BASIN ACCOMPLISHMENT PLAN, APRIL 1973

    EPA Science Inventory

    The Upper Snake Accomplishment Basin (17040104, 170402, 170501) is defined as the Idaho and Oregon portions of 2 STORET Basins, the Upper Snake Basin and the Central Snake Basin. The Basin drains approximately 62,100 square miles in Southern Idaho and Southeastern Oregon. Four ...

  12. Final report on technical work accomplished under contract NASw-2953

    NASA Technical Reports Server (NTRS)

    Fredricks, R. W.

    1977-01-01

    A report is given on the technical work accomplished in the area of plasma physics. The subjects covered are: (1) oblique whistler instabilities, (2) current-limited electron beam injection, (3) three-dimensional ion sound turbulence, (4) theoretical aspects of sounder antenna operation and (5) whistler modes in bow shock structures.

  13. 38 CFR 39.120 - Documentation of grant accomplishments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Documentation of grant accomplishments. 39.120 Section 39.120 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) AID FOR THE ESTABLISHMENT, EXPANSION, AND IMPROVEMENT, OR OPERATION AND MAINTENANCE, OF...

  14. 38 CFR 39.120 - Documentation of grant accomplishments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Documentation of grant accomplishments. 39.120 Section 39.120 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) AID FOR THE ESTABLISHMENT, EXPANSION, AND IMPROVEMENT, OR OPERATION AND MAINTENANCE, OF...

  15. 38 CFR 39.120 - Documentation of grant accomplishments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Documentation of grant accomplishments. 39.120 Section 39.120 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) AID FOR THE ESTABLISHMENT, EXPANSION, AND IMPROVEMENT, OR OPERATION AND MAINTENANCE, OF...

  16. 38 CFR 39.120 - Documentation of grant accomplishments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Documentation of grant accomplishments. 39.120 Section 39.120 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) AID TO STATES FOR ESTABLISHMENT, EXPANSION, AND IMPROVEMENT, OR OPERATION AND MAINTENANCE,...

  17. Identifying bio-physical, social and political challenges to catchment governance for sustainable freshwater fisheries in West Africa: Systems overview through scenario development in the SUSFISH project.

    NASA Astrophysics Data System (ADS)

    Sendzimir, Jan; Slezak, Gabriele; Melcher, Andreas

    2015-04-01

    Chronic and episodic water scarcity prompted construction of 1400 reservoirs in Burkina Faso since 1950, greatly expanding fisheries production. These fisheries provided an increasingly important protein source for a population that has risen 600% since 1920, but production has plateaued, and dramatic declines in adult fish size suggest these fisheries are not sustainable. The SUSFISH project joined Austrian and Burkinabe scientists to increase local capacities to manage fisheries sustainably. SUSFISH has successfully increased capacity to monitor fish populations, identify endangered species, and use specific fish and macroinvertebrate species as bio-indicators of water and habitat quality as well as anthropogenic pressures. But projects to support sustainable development in Africa have a long history of failure if only based on transfer of technology and theory based on bio-physical sciences. This paper describes the processes and products of knowledge elicitation, scenario development and systems analysis to identify barriers and bridges to long-term sustainable fisheries development that arise from bio-physical, social, political and cultural causes, and, especially, interactions between them. Lessons learned and important on-going research questions are identified for both the natural and social sciences as they apply to managing catchments at multiple scales of governance, from local to national.

  18. Diversity, Pedagogy and Higher Education: Challenges, Lessons and Accomplishments. Trotter Review, 1998.

    ERIC Educational Resources Information Center

    Jennings, James, Ed.

    This publication presents a collection of articles on diversity, pedagogy, and higher education. They include: "Introduction" (James Jennings); "Faculty Diversity: Effective Strategies for the Recruitment and Retention of Faculty of Color" (Sheila T. Gregory); "The Dream of Diversity and the Cycle of Exclusion" (Stephanie M Wildman); "Obstacles…

  19. Evolution of Research Universities as a National Research System in Korea: Accomplishments and Challenges

    ERIC Educational Resources Information Center

    Shin, Jung Cheol; Lee, Soo Jeung

    2015-01-01

    This article focuses on South Korea, where the basis of the economy rapidly transformed from labor-intensive industries to heavy/chemical industries and then to technology-based industries within a short time period. The Korean case shows how national research systems evolve along with economic development. On the other hand, such rapid research…

  20. The establishment of an attachment research network in Latin America: goals, accomplishments, and challenges.

    PubMed

    Causadias, José M; Sroufe, L Alan; Herreros, Francisca

    2011-03-01

    In the face of a pressing need for expanded attachment research programs and attachment informed interventions in Latin America, a research network was established: Red Iberoamericana de Apego: RIA (Iberian-American Attachment Network). The purpose of RIA is to promote human development and well being, informed by attachment theory, centering on research, and with implications for public policies, education, and intervention. We report the proceedings of the second meeting of RIA held in Panama City, Panama, in February 2010. As part of this meeting, RIA sponsored the first Latin-American attachment conference. Proceedings of the conference are described, as are future goals of this new organization. PMID:21390910

  1. Hydropodelogy From the Pedon to the Landscape: Challenges and Accomplishments in the National Cooperative Soil Survey

    NASA Astrophysics Data System (ADS)

    Hammer, D.; Richardson, J.; Hempel, J.; Market, P.

    2005-12-01

    American pedology has focused on the National Cooperative Soil Survey. Primary responsibility rests with the U.S. Department of Agriculture. The primary goals, are legislatively mandated, are to map the country's soils, make interpretations, provide information to clients, maintain and market the soil survey. The first goal is near completion and focus is shifting to the other three. Concomitantly, American pedological science is being impacted by several conditions: technological advances; land use changes at unprecedented scales and magnitudes; a burgeoning population increasingly "separated" from the land; and a major emphasis in universities upon biological ("life") sciences at the DNA scale - as if soil, nutrients and water are not life essentials. Effects of the Flood of 1993 and Hurricane Katrina suggest that humans do not understand earth/climate interactions, particularly climatic extremes. Pedologists know the focus on soil classification and mapping was at the expense of understanding processes. Hydropedology is a holistic approach to understanding soil and geomorphic process in order to predict the impacts of perturbations. Water movement on and in the soil is the primary mechanism of distributing and altering sediments and chemicals (pedogenesis), and depends for its success upon understanding that the soil profile is the record of developmental history at that landscape site. Hydropedologists believe soil scientists can use pedons (point data) from appropriate locations from flownets in complex landscapes to extrapolate processes. This is the "pedotransfer function" concept. Technological advances are coupled with the existing soil survey information to create important soil-landscape interpretations at a variety of scales. Early results have been very successful. Quantification of soil systems can be classified broadly into three categories; hard data, soft data and tacit knowledge. "Hard data" are measured numbers, and include such attributes as pH, texture, cation exchange capacity and event-specific rainfall. "Soft data" include soil maps, SSURGO data and climate maps. Soft data are combinations of observations, measurements and inferences that produce maps and models at various scales. "Tacit knowledge" is human understanding that results from focused experience within a system. A skilled soil scientist with tacit knowledge specific to a particular region can combination hard and soft data to develop important and useful interpretations and predictions. Illustrations from natural and urban settings will be provided. Soils and climate are temporally and spatially variable at all scales. Soil systems respond differently to different climates and perturbations. For example, the recent pluvial period in the Prairie Pothole region is changing surface soil sodium concentrations and locations and sizes of discharge wetlands. This is a relatively short-term response to a regional climate shift. Climatic shift in Oxisol landscapes will have little effect on soil cations. To optimize soil interpretations, focus must be on quantifying region-specific "dynamic" soil, geomorphic and climatic attributes. Recognizing these needs, the National Cooperative Soil Survey will develop regional watershed projects that focus on quantifying soil-water relationships that can be used at a variety of scales.

  2. Palliative cancer care in Middle Eastern countries: accomplishments and challenges

    PubMed Central

    Silbermann, M.; Arnaout, M.; Daher, M.; Nestoros, S.; Pitsillides, B.; Charalambous, H.; Gultekin, M.; Fahmi, R.; Mostafa, K.A.H.; Khleif, A.D.; Manasrah, N.; Oberman, A.

    2012-01-01

    Background In larger parts of the Middle East palliative care is still misunderstood among health professionals, cancer patients and the public at large. One reason to that is because the term does not obviously communicate the intent of this clinical discipline, which is lending better quality of life while combating cancer. Further, culture, tradition and religion have contributed to this misgiving and confusion especially at the terminal stage of the disease. Methods The Middle East Cancer Consortium jointly with the American Society of Clinical Oncology, the American Oncology Nursing Society, the San Diego Hospice Center for Palliative Medicine and the Children's Hospital & Clinics of Minnesota initiated a series of training courses and workshops in the Middle East to provide updated training to physicians, nurses, social workers and psychologists from throughout the region with basic concepts of palliative care and pain managements in adults and children cancers. Results During the past 6 years hundreds of professionals took part in these educational and training activities, thereby creating the core of trained caregivers who start to make the change in their individual countries. Conclusions The outcome of consecutive training activities can overcome geopolitical instabilities, and yield a genuine change in approach of both regulators, medical administrators, medical staff and the public; as to the important contribution of palliative care services to the welfare of the patient and his/her family. PMID:22628412

  3. Educational Accomplishment Audit: Past, Present, and Future. Proceedings of A National Symposium on Perspectives on Educational Accomplishment Auditing.

    ERIC Educational Resources Information Center

    Cook, Desmond L., Ed.; Stoycheff, Peter A., Ed.

    The papers comprising these proceedings discuss the nature and purpose of the Independent Educational Accomplishment Audit (IEAA), a concept born in the late 1960's to establish accountability for mandatory technical assistance programs funded by the Elementary and Secondary Education Act: (1) origins and rationale of the Independent Educational…

  4. Sharing the tracks to good tucker: identifying the benefits and challenges of implementing community food programs for Aboriginal communities in Victoria.

    PubMed

    Murray, Margaret; Bonnell, Emily; Thorpe, Sharon; Browne, Jennifer; Barbour, Liza; MacDonald, Catherine; Palermo, Claire

    2014-01-01

    Food insecurity is a significant issue in the Victorian Aboriginal population, contributing to the health disparity and reduced life expectancy. Community food programs are a strategy used to minimise individual level food insecurity, with little evidence regarding their effectiveness for Aboriginal populations. The aim of this study was to explore the role of community food programs operating for Aboriginal people in Victoria and their perceived influence on food access and nutrition. Semistructured interviews were conducted with staff (n=23) from a purposive sample of 18 community food programs across Victoria. Interviews explored the programs' operation, key benefits to the community, challenges and recommendations for setting up a successful community food program. Results were analysed using a qualitative thematic approach and revealed three main themes regarding key factors for the success of community food programs: (1) community food programs for Aboriginal people should support access to safe, affordable, nutritious food in a socially and culturally acceptable environment; (2) a community development approach is essential for program sustainability; and (3) there is a need to build the capacity of community food programs as part of a strategy to ensure sustainability. Community food programs may be an effective initiative for reducing food insecurity in the Victorian Aboriginal population. PMID:25116591

  5. Recent Accomplishments in the Irradiation Testing of Engineering-Scale Monolithic Fuel Specimens

    SciTech Connect

    N.E. Woolstenhulme; D.M. Wachs; M.K. Meyer; H.W. Glunz; R.B. Nielson

    2012-10-01

    The US fuel development team is focused on qualification and demonstration of the uranium-molybdenum monolithic fuel including irradiation testing of engineering-scale specimens. The team has recently accomplished the successful irradiation of the first monolithic multi-plate fuel element assembly within the AFIP-7 campaign. The AFIP-6 MKII campaign, while somewhat truncated by hardware challenges, exhibited successful irradiation of a large-scale monolithic specimen under extreme irradiation conditions. The channel gap and ultrasonic data are presented for AFIP-7 and AFIP-6 MKII, respectively. Finally, design concepts are summarized for future irradiations such as the base fuel demonstration and design demonstration experiment campaigns.

  6. Toxic effect on tissues and differentially expressed genes in hepatopancreas identified by suppression subtractive hybridization of freshwater pearl mussel (Hyriopsis cumingii) following microcystin-LR challenge.

    PubMed

    Yang, Ziyan; Wu, Hongjuan; Li, Yuan

    2012-07-01

    Microcystins are a family of potent hepatotoxins produced by freshwater cyanobacteria and can cause animal intoxications and human diseases. In this study, the effect of microcystin-LR (MC-LR) on the tissues of freshwater pearl mussel (Hyriopsis cumingii) was evaluated and differentially expressed genes in the hepatopancreas of the mussel exposed to MC-LR were identified. HPLC analysis of cell extracts from various tissues of the mussel indicated that the hepatopancreas had the highest MC-LR levels (55.78 ± 6.73 μg g⁻¹ DW) after 15-day exposure. The MC-LR concentration in gill or muscle was an order of magnitude less than in hepatopancreas or gonad. Subtractive cDNA library was constructed by suppression subtractive hybridization (SSH), and ∼400 positive clones were sequenced, from which 98 high quality sequences were obtained by BLAST analysis. The screening identified numerous genes involved in apoptosis, signal transduction, cytoskeletal remodel, innate immunity, material and energy metabolism, translation and transcription which were extensively discussed. The results of this study add large amount of information to the mussel genome data, and for the first time present the basic data on toxicity effect of MC-LR on mussel. PMID:20957730

  7. The 1992-1993 NASA Space Biology Accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1994-01-01

    This report consists of individual technical summaries of research projects of NASA's Space Biology Program, for research conducted during the calendar years of 1992 and 1993. This program includes both plant and animal research, and is dedicated to understanding the role of gravity and the effects of microgravity on biological processes; determining the effects of the interaction of gravity and other environmental factors on biological systems; and using the microgravity of the space environment as a tool to advance fundamental scientific knowledge in the biological sciences to improve the quality of life on Earth and contribute to NASA's goal of manned exploration of space. The summaries for each project include a description of the research, a list of the accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  8. The 1990-1991 NASA space biology accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, Thora W. (Editor)

    1993-01-01

    This report consists of individual technical summaries of research projects of NASA's Space Biology Program, for research conducted during the period May 1990 through May 1991. This program includes both plant and animal research, and is dedicated to understanding the role of gravity and other environmental factors on biological systems and to using the microgravity of the space environment as a tool to advance fundamental scientific knowledge in the biological sciences to improve the quality of life on Earth and contribute to NASA's goal of manned exploration of space. The summaries for each project include a description of the research, a list of the accomplishments, an explanation of the significance of the accomplishments, and a list of publications.

  9. FY 1995 research highlights: PNL accomplishments in OER programs

    SciTech Connect

    1995-10-01

    Pacific Northwest Laboratory (PNL) conducts fundamental and applied research in support of the US Department of Energy`s (DOE) core missions in science and technology, environmental quality, energy resources, and national security. Much of this research is funded by the program offices of DOE`s Office of Energy Research (DOE-ER), primarily the Office of Basic Energy Sciences (BES) and the Office of Health and Environmental Research (OHER), and by PNL`s Laboratory Directed Research and Development (LDRD) Program. This document is a collection of research highlights that describe PNL`s accomplishments in DOE-ER funded programs during Fiscal Year 1995. Included are accomplishments in research funded by OHER`s Analytical Technologies, Environmental Research, Health Effects, General Life Sciences, and Carbon Dioxide Research programs; BES`s Materials Science, Chemical Sciences, Engineering and Geoscience, and Applied Mathematical Sciences programs; and PNL`s LDRD Program. Summaries are given for 70 projects.

  10. Abstract and research accomplishments of University Coal Research Projects

    SciTech Connect

    1995-06-01

    The Principal Investigators of the grants supported by the University Coal Research Program were requested to submit abstracts and highlight accomplishments of their respective projects in time for distribution at a conference on June 13--14, 1995 at Tennessee State University in Nashville, Tennessee. This book is a compilation of the material received in response to that request. For convenience, the 70 grants reported in this book are stored into eight technical areas, Coal Science, Coal Surface Science, Reaction Chemistry, Advanced Process Concepts, Engineering Fundamentals and Thermodynamics, Environmental Science, high Temperature Phenomena, and Special topics. Indexes are provided for locating projects by subject, principal investigators, and contracting organizations. Each extended abstract describes project objectives, work accomplished, significance to the Fossil Energy Program, and plans for the next year.

  11. Challenges in Identifying and Managing Attention-Deficit/Hyperactivity Disorder in Adults in the Primary Care Setting: A Review of the Literature

    PubMed Central

    Mattingly, Gregory

    2010-01-01

    Objective: To examine how to screen for and establish a correct diagnosis of attention-deficit/hyperactivity disorder (ADHD) in adults and to identify the outcomes associated with untreated ADHD. Data Sources: PubMed was searched using the key words ADHD, adult, diagnosis, and primary care from the years 1999 to 2009. Study Selection: This search produced 50 publications. Data Extraction: Publications were screened for data specific to the diagnosis or management of adult patients with ADHD in the primary care setting. Data Synthesis: The estimated prevalence of ADHD in adults throughout the United States is 4.4% or approximately 10 million adults. Adults with ADHD by definition must experience impairment from the symptoms of ADHD in at least 2 areas of their life. Despite significant impairment, only 1 in 10 adults with ADHD have received ADHD treatment within the past year. Given the high rates of undertreatment, primary care physicians, who provide much of the general adult mental health care in the United States, are increasingly charged with making the diagnosis of ADHD in adults. ADHD symptoms are often masked by comorbid psychiatric conditions or patient adaptations such as choice of occupation. One of the ADHD assessment tools, a short 6-item screener, can simplify identification and management of ADHD in adults and help identify which patients may require further evaluation. Conclusions: Primary care physicians should consult with other members of the health care community such as psychiatrists and psychologists when necessary, but should also develop a level of comfort with diagnosing and treating ADHD. PMID:21494335

  12. The eighth NASA total quality management accomplishments report, 1990

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The eighth annual accomplishments report provides numerous examples of quality strategies that have proven effective and efficient in a time when cost reduction is critical. NASA's continuous improvement efforts can provide insight for others to succeed in their own endeavors. The report covers: top management leadership and support, strategic planning, focus on the customer, employee training and recognition, employee empowerment and teamwork, measurement and analysis, and quality assurance.

  13. Abstracts and research accomplishments of university coal research projects

    SciTech Connect

    Not Available

    1991-06-01

    The Principal Investigators of the grants supported by the University Coal Research Program were requested to submit abstracts and highlight accomplishments of their projects in time for distribution at a grantees conference. This book is a compilation of the material received in response to the request. Abstracts discuss the following area: coal science, coal surface science, reaction chemistry, advanced process concepts, engineering fundamentals and thermodynamics, environmental science.

  14. NGNP Process Heat Applications: Hydrogen Production Accomplishments for FY2010

    SciTech Connect

    Charles V Park

    2011-01-01

    This report summarizes FY10 accomplishments of the Next Generation Nuclear Plant (NGNP) Engineering Process Heat Applications group in support of hydrogen production technology development. This organization is responsible for systems needed to transfer high temperature heat from a high temperature gas-cooled reactor (HTGR) reactor (being developed by the INL NGNP Project) to electric power generation and to potential industrial applications including the production of hydrogen.

  15. 2012 ACCOMPLISHMENTS - TRITIUM AGING STUDIES ON STAINLESS STEELS

    SciTech Connect

    Morgan, M.

    2013-01-31

    This report summarizes the research and development accomplishments during FY12 for the tritium effects on materials program. The tritium effects on materials program is designed to measure the long-term effects of tritium and its radioactive decay product, helium-3, on the structural properties of forged stainless steels which are used as the materials of construction for tritium reservoirs. The FY12 R&D accomplishments include: (1) Fabricated and Thermally-Charged 150 Forged Stainless Steel Samples with Tritium for Future Aging Studies; (2) Developed an Experimental Plan for Measuring Cracking Thresholds of Tritium-Charged-and-Aged Steels in High Pressure Hydrogen Gas; (3) Calculated Sample Tritium Contents For Laboratory Inventory Requirements and Environmental Release Estimates; (4) Published report on “Cracking Thresholds and Fracture Toughness Properties of Tritium-Charged-and-Aged Stainless Steels”; and, (5) Published report on “The Effects of Hydrogen, Tritium, and Heat Treatment on the Deformation and Fracture Toughness Properties of Stainless Steels”. These accomplishments are highlighted here and references given to additional reports for more detailed information.

  16. A Rare HBV Subgenotype D4 with Unique Genomic Signatures Identified in North-Eastern India –An Emerging Clinical Challenge?

    PubMed Central

    Banerjee, Priyanka; Mondal, Rajiv Kumar; Nandi, Madhuparna; Ghosh, Sumantra; Khatun, Mousumi; Chakraborty, Nabendu; Bhattacharya, Swatilekha; RoyChoudhury, Arindam; Banerjee, Soma; Santra, Amal; Sil, Samir; Chowdhury, Abhijit; Bhaumik, Pradip; Datta, Simanti

    2014-01-01

    Background/Aims HBV has been classified into ten genotypes (A–J) and multiple subgenotypes, some of which strongly influence disease outcome and their distribution also correlate with human migration. HBV infection is highly prevalent in India and its diverse population provides an excellent opportunity to study the distinctiveness of HBV, its evolution and disease biology in variegated ethnic groups. The North-East India, having international frontiers on three sides, is one of the most ethnically and linguistically diverse region of the country. Given the paucity of information on molecular epidemiology of HBV in this region, the study aimed to carry out an in-depth genetic characterization of HBV prevailing in North-East state of Tripura. Methods From sera of chronically HBV infected patients biochemical/serological tests, HBV DNA quantification, PCR-amplification, sequencing of PreS/S or full-length HBV genomes were done. HBV genotype/subgenotype determination and sequence variability were assessed by MEGA5-software. The evolutionary divergence times of different HBV subgenotypes were estimated by DNAMLK/PHYLIP program while jpHMM method was used to detect any recombination event in HBV genomes. Results HBV genotypes D (89.5%), C (6.6%) and A (3.9%) were detected among chronic carriers. While all HBV/A and HBV/C isolates belonged to subgenotype-A1 and C1 respectively, five subgenotypes of HBV/D (D1–D5) were identified including the first detection of rare D4. These non-recombinant Indian D4 (IndD4) formed a distinct phylogenetic clade, had 2.7% nucleotide divergence and recent evolutionary radiation than other global D4. Ten unique amino acids and 9 novel nucleotide substitutions were identified as IndD4 signatures. All IndD4 carried T120 and R129 in ORF-S that may cause immune/vaccine/diagnostic escape and N128 in ORF-P, implicated as compensatory Lamivudine resistance mutation. Conclusions IndD4 has potential to undermine vaccination programs or anti

  17. Under the radar: a cross-sectional study of the challenge of identifying at-risk alcohol consumption in the general practice setting

    PubMed Central

    2014-01-01

    Background Primary care providers are an important source of information regarding appropriate alcohol consumption. As early presentation to a provider for alcohol-related concerns is unlikely, it is important that providers are able to identify at-risk patients in order to provide appropriate advice. This study aimed to report the sensitivity, specificity, positive predictive value and negative predictive value of General Practitioner (GP) assessment of alcohol consumption compared to patient self-report, and explore characteristics associated with GP non-detection of at-risk status. Method GP practices were selected from metropolitan and regional locations in Australia. Eligible patients were adults presenting for general practice care who were able to understand English and provide informed consent. Patients completed a modified AUDIT-C by touchscreen computer as part of an omnibus health survey while waiting for their appointment. GPs completed a checklist for each patient, including whether the patient met current Australian guidelines for at-risk alcohol consumption. Patient self-report and GP assessments were compared for each patient. Results GPs completed the checklist for 1720 patients, yielding 1565 comparisons regarding alcohol consumption. The sensitivity of GPs’ detection of at-risk alcohol consumption was 26.5%, with specificity of 96.1%. Higher patient education was associated with GP non-detection of at-risk status. Conclusions GP awareness of which patients might benefit from advice regarding at-risk alcohol consumption appears low. Given the complexities associated with establishing whether alcohol consumption is ‘at-risk’, computer-based approaches to routine screening of patients are worthy of exploration as a method for prompting the provision of advice in primary care. PMID:24766913

  18. Label-Free Impedance Biosensors: Opportunities and Challenges

    PubMed Central

    Daniels, Jonathan S.; Pourmand, Nader

    2007-01-01

    Impedance biosensors are a class of electrical biosensors that show promise for point-of-care and other applications due to low cost, ease of miniaturization, and label-free operation. Unlabeled DNA and protein targets can be detected by monitoring changes in surface impedance when a target molecule binds to an immobilized probe. The affinity capture step leads to challenges shared by all label-free affinity biosensors; these challenges are discussed along with others unique to impedance readout. Various possible mechanisms for impedance change upon target binding are discussed. We critically summarize accomplishments of past label-free impedance biosensors and identify areas for future research. PMID:18176631

  19. Accomplishments of the Oak Ridge National Laboratory Seed Money program

    DOE R&D Accomplishments Database

    1986-09-01

    In 1974, a modest program for funding new, innovative research was initiated at ORNL. It was called the "Seed Money" program and has become part of a larger program, called Exploratory R and D, which is being carried out at all DOE national laboratories. This report highlights 12 accomplishments of the Seed Money Program: nickel aluminide, ion implantation, laser annealing, burn meter, Legionnaires' disease, whole-body radiation counter, the ANFLOW system, genetics and molecular biology, high-voltage equipment, microcalorimeter, positron probe, and atom science. (DLC)

  20. 2008 Accomplishments for CEV Parachute Assembly System (CPAS)

    NASA Technical Reports Server (NTRS)

    Martin, Ricardo

    2009-01-01

    The Crew Exploration Vehicle (CEV) Parachute Assembly System (CPAS) project is responsible for the design, development, fabrication, qualification and delivery of the CEV parachute system to support the Orion pad/ascent flight tests and the first three orbital flight tests (including the first human mission). This article will discuss the technical and research achievements accomplished in calendar year 2008, broken into three key categories: prototype testing and analysis (also referred to as the Generation 1 design), system requirements definition and design of the flight engineering development unit, and support for the Orion vehicle flight testing (primarily Pad-Abort 1).

  1. Accomplishments of the Oak Ridge National Laboratory Seed Money program

    SciTech Connect

    Not Available

    1986-09-01

    In 1974, a modest program for funding new, innovative research was initiated at ORNL. It was called the ''Seed Money'' program and has become part of a larger program, called Exploratory R and D, which is being carried out at all DOE national laboratories. This report highlights 12 accomplishments of the Seed Money Program: nickel aluminide, ion implantation, laser annealing, burn meter, Legionnaires' disease, whole-body radiation counter, the ANFLOW system, genetics and molecular biology, high-voltage equipment, microcalorimeter, positron probe, and atom science. (DLC)

  2. Environmental Measurements Laboratory fiscal year 1998: Accomplishments and technical activities

    SciTech Connect

    Erickson, M.D.

    1999-01-01

    The Environmental Measurements Laboratory (EML) is government-owned, government-operated, and programmatically under the DOE Office of Environmental Management. The Laboratory is administered by the Chicago Operations Office. EML provides program management, technical assistance and data quality assurance for measurements of radiation and radioactivity relating to environmental restoration, global nuclear nonproliferation, and other priority issues for the Department of Energy, as well as for other government, national, and international organizations. This report presents the technical activities and accomplishments of EML for Fiscal Year 1998.

  3. Material Recovery and Waste Form Development FY 2015 Accomplishments Report

    SciTech Connect

    Todd, Terry Allen; Braase, Lori Ann

    2015-11-01

    The Material Recovery and Waste Form Development (MRWFD) Campaign under the U.S. Department of Energy (DOE) Fuel Cycle Technologies (FCT) Program is responsible for developing advanced separation and waste form technologies to support the various fuel cycle options defined in the DOE Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. The FY 2015 Accomplishments Report provides a highlight of the results of the research and development (R&D) efforts performed within the MRWFD Campaign in FY-14. Each section contains a high-level overview of the activities, results, technical point of contact, applicable references, and documents produced during the fiscal year. This report briefly outlines campaign management and integration activities, but primarily focuses on the many technical accomplishments made during FY-15. The campaign continued to utilize an engineering driven-science-based approach to maintain relevance and focus. There was increased emphasis on development of technologies that support near-term applications that are relevant to the current once-through fuel cycle.

  4. California's “Bridge to Reform”: Identifying Challenges and Defining Strategies for Providers and Policymakers Implementing the Affordable Care Act in Low-Income HIV/AIDS Care and Treatment Settings

    PubMed Central

    Hazelton, Patrick T.; Steward, Wayne T.; Collins, Shane P.; Gaffney, Stuart; Morin, Stephen F.; Arnold, Emily A.

    2014-01-01

    Background In preparation for full Affordable Care Act implementation, California has instituted two healthcare initiatives that provide comprehensive coverage for previously uninsured or underinsured individuals. For many people living with HIV, this has required transition either from the HIV-specific coverage of the Ryan White program to the more comprehensive coverage provided by the county-run Low-Income Health Programs or from Medicaid fee-for-service to Medicaid managed care. Patient advocates have expressed concern that these transitions may present implementation challenges that will need to be addressed if ambitious HIV prevention and treatment goals are to be achieved. Methods 30 semi-structured, in-depth interviews were conducted between October, 2012, and February, 2013, with policymakers and providers in 10 urban, suburban, and rural California counties. Interview topics included: continuity of patient care, capacity to handle payer source transitions, and preparations for healthcare reform implementation. Study team members reviewed interview transcripts to produce emergent themes, develop a codebook, build inter-rater reliability, and conduct analyses. Results Respondents supported the goals of the ACA, but reported clinic and policy-level challenges to maintaining patient continuity of care during the payer source transitions. They also identified strategies for addressing these challenges. Areas of focus included: gaps in communication to reach patients and develop partnerships between providers and policymakers, perceived inadequacy in new provider networks for delivering quality HIV care, the potential for clinics to become financially insolvent due to lower reimbursement rates, and increased administrative burdens for clinic staff and patients. Conclusions California's new healthcare initiatives represent ambitious attempts to expand and improve health coverage for low-income individuals. The state's challenges in maintaining quality care and

  5. CEMENTITIOUS BARRIERS PARTNERSHIP ACCOMPLISHMENTS AND RELEVANCE TO THE DOE COMPLEX

    SciTech Connect

    Burns, H.; Langton, C.; Flach, G.; Kosson, D.

    2010-11-15

    The Cementitious Barriers Partnership (CBP) was initiated to reduce risk and uncertainties in the performance assessments that directly impact U.S. Department of Energy (DOE) environmental cleanup and closure programs. The CBP is supported by the DOE Office of Environmental Management (DOE-EM) and has been specifically addressing the following critical EM program needs: (i) the long-term performance of cementitious barriers and materials in nuclear waste disposal facilities and (ii) increased understanding of contaminant transport behavior within cementitious barrier systems to support the development and deployment of adequate closure technologies. To accomplish this, the CBP has two initiatives: (1) an experimental initiative to increase understanding of changes in cementitious materials over long times (> 1000 years) over changing conditions and (2) a modeling initiative to enhance and integrate a set of computational tools validated by laboratory and field experimental data to improve understanding and prediction of the long-term performance of cementitious barriers and waste forms used in nuclear applications. In FY10, the CBP developed the initial phase of an integrated modeling tool that would serve as a screening tool which could help in making decisions concerning disposal and tank closure. The CBP experimental programs are underway to validate this tool and provide increased understanding of how CM changes over time and under changing conditions. These initial CBP products that will eventually be enhanced are anticipated to reduce the uncertainties of current methodologies for assessing cementitious barrier performance and increase the consistency and transparency of the DOE assessment process. These tools have application to low activity waste forms, high level waste tank closure, D&D and entombment of major nuclear facilities, landfill waste acceptance criteria, and in-situ grouting and immobilization of vadose zone contamination. This paper summarizes

  6. Fiscal Year 2005 Solar Radiometry and Metrology Task Accomplishments

    SciTech Connect

    Myers, D.; Andreas, A.; Reda, I.; Gotseff, P.; Wilcox, S.; Stoffel, T.; Anderberg, M.; Kay, B.; Bowen, A.

    2005-11-01

    The National Renewable Energy Laboratory (NREL) Solar Radiometry and Metrology task provides traceable optical radiometric calibrations and measurements to photovoltaic (PV) researchers and the PV industry. Traceability of NREL solar radiometer calibrations to the World Radiometric Reference (WRR) was accomplished during Pyrheliometer Comparison at NREL in October 2004. Ten spectral and more than 200 broadband radiometers for solar measurements were calibrated this year. We measured detailed spectral distributions of the NREL and PV industry Pulsed Solar Simulators and are analyzing the influence of environmental variables on radiometer uncertainty. New systems for indoor and outdoor solar radiometer calibrations and ultraviolet (UV) spectral measurements and UV radiometer calibrations were purchased and tested. Optical metrology functions support the NREL Measurement and Characterization Task effort for ISO 17025 accreditation of NREL Solar Reference Cell Calibrations and have been integrated into the NREL quality system and audited for ISO17025 compliance.

  7. Recent Accomplishments in Laser-Photovoltaic Wireless Power Transmission

    NASA Technical Reports Server (NTRS)

    Fikes, John C.; Henley, Mark W.; Mankins, John C.; Howell, Joe T.; Fork, Richard L.; Cole, Spencer T.; Skinner, Mark

    2003-01-01

    Wireless power transmission can be accomplished over long distances using laser power sources and photovoltaic receivers. Recent research at AMOS has improved our understanding of the use of this technology for practical applications. Research by NASA, Boeing, the University of Alabama-Huntsville, the University of Colorado, Harvey Mudd College, and the Naval Postgraduate School has tested various commercial lasers and photovoltaic receiver configurations. Lasers used in testing have included gaseous argon and krypton, solid-state diodes, and fiber optic sources, at wavelengths ranging from the visible to the near infra-red. A variety of Silicon and Gallium Arsenide photovoltaic have been tested with these sources. Safe operating procedures have been established, and initial tests have been conducted in the open air at AMOS facilities. This research is progressing toward longer distance ground demonstrations of the technology and practical near-term space demonstrations.

  8. When Social Support Is Uncomfortable. The Communicative Accomplishment of Support as a Cultural Term in a Youth Intervention Program.

    ERIC Educational Resources Information Center

    Sass, James S.; Mattson, Marifran

    1999-01-01

    Expands understanding of social support by addressing the communicative use of support in a community program for troubled teens. Presents the ways in which the organization accomplishes and constructs support. Identifies and explores two novel aspects of supportive communication: supportive communication that may be perceived as uncomfortable and…

  9. Sigma Team for Advanced Actinide Recycle FY2015 Accomplishments and Directions

    SciTech Connect

    Moyer, Bruce A.

    2015-09-30

    The Sigma Team for Minor Actinide Recycle (STAAR) has made notable progress in FY 2015 toward the overarching goal to develop more efficient separation methods for actinides in support of the United States Department of Energy (USDOE) objective of sustainable fuel cycles. Research in STAAR has been emphasizing the separation of americium and other minor actinides (MAs) to enable closed nuclear fuel recycle options mainly within the paradigm of aqueous reprocessing of used oxide nuclear fuel dissolved in nitric acid. Its major scientific challenge concerns achieving selectivity for trivalent actinides vs lanthanides. Not only is this challenge yielding to research advances, but technology concepts such as ALSEP (Actinide Lanthanide Separation) are maturing toward demonstration readiness. Efforts are organized in five task areas: 1) combining bifunctional neutral extractants with an acidic extractant to form a single process solvent, developing a process flowsheet, and demonstrating it at bench scale; 2) oxidation of Am(III) to Am(VI) and subsequent separation with other multivalent actinides; 3) developing an effective soft-donor solvent system for An(III) selective extraction using mixed N,O-donor or all-N donor extractants such as triazinyl pyridine compounds; 4) testing of inorganic and hybrid-type ion exchange materials for MA separations; and 5) computer-aided molecular design to identify altogether new extractants and complexants and theory-based experimental data interpretation. Within these tasks, two strategies are employed, one involving oxidation of americium to its pentavalent or hexavalent state and one that seeks to selectively complex trivalent americium either in the aqueous phase or the solvent phase. Solvent extraction represents the primary separation method employed, though ion exchange and crystallization play an important role. Highlights of accomplishments include: Confirmation of the first-ever electrolytic oxidation of Am(III) in a

  10. Radiation Safety Training for Industrial Irradiators: What Are We Trying To Accomplish?

    NASA Astrophysics Data System (ADS)

    Smith, M. A.

    1998-06-01

    Radiation safety training at an industrial irradiator facility takes a different approach than the traditional methods and topics used at other facilities. Where the more routine industrial radiation users focus on standard training topics of contamination control, area surveys, and the traditional dogma of time, distance, and shielding, radiation safety in an industrial irradiation facility must be centered on preventing accidents. Because the primary methods for accomplishing that goal are engineering approaches such as safety system interlocks, training provided to facility personnel should address system operation and emergency actions. This presents challenges in delivering radiation safety to an audience of varied educational and technical background where little to no commercially available training material specific to this type of operation exists.

  11. National Climate Change and Wildlife Science Center project accomplishments: highlights

    USGS Publications Warehouse

    Holl, Sally

    2011-01-01

    The National Climate Change and Wildlife Science Center (NCCWSC) has invested more than $20M since 2008 to put cutting-edge climate science research in the hands of resource managers across the Nation. With NCCWSC support, more than 25 cooperative research initiatives led by U.S. Geological Survey (USGS) researchers and technical staff are advancing our understanding of habitats and species to provide guidance to managers in the face of a changing climate. Projects focus on quantifying and predicting interactions between climate, habitats, species, and other natural resources such as water. Spatial scales of the projects range from the continent of North America, to a regional scale such as the Pacific Northwest United States, to a landscape scale such as the Florida Everglades. Time scales range from the outset of the 20th century to the end of the 21st century. Projects often lead to workshops, presentations, publications and the creation of new websites, computer models, and data visualization tools. Partnership-building is also a key focus of the NCCWSC-supported projects. New and on-going cooperative partnerships have been forged and strengthened with resource managers and scientists at Federal, tribal, state, local, academic, and non-governmental organizations. USGS scientists work closely with resource managers to produce timely and relevant results that can assist managers and policy makers in current resource management decisions. This fact sheet highlights accomplishments of five NCCWSC projects.

  12. The Mixed Waste Focus Area: Status and accomplishments

    SciTech Connect

    Conner, J.E.; Williams, R.E.

    1997-08-01

    The Mixed Waste Focus Area began operations in February of 1995. Its mission is to provide acceptable technologies that enable implementation of mixed waste treatment systems developed in partnership with end-users, stakeholders, tribal governments, and regulators. The MWFA will develop, demonstrate, and deliver implementable technologies for treatment of mixed waste within the DOE complex. Treatment refers to all post waste-generation activities including sampling and analysis, characterization, storage, processing, packaging, transportation, and disposal. The MWFA`s mission arises from the Resources Conservation and Recovery Act (RCRA) as amended by the Federal Facility Compliance Act. Each DOE site facility that generates or stores mixed waste prepared a plan, the Site Treatment Plan, for developing treatment capacities and treating that waste. Agreements for each site were concluded with state regulators, resulting in Consent Orders providing enforceable milestones for achieving treatment of the waste. The paper discusses the implementation of the program, its status, accomplishments and goals for FY1996, and plans for 1997.

  13. Research accomplishments and future goals in particle physics

    NASA Astrophysics Data System (ADS)

    1994-06-01

    This proposal presents the research accomplishments and ongoing activities of Boston University researchers in high energy physics. Some changes have been made in the structure of the program from the previous arrangement of tasks. Task B, Accelerator Design Physics, is being submitted as a separate proposal for an independent grant; this will be consistent with the nature of the research and the source of funding. Boston University is active in seven principal areas: (1) Task A: Colliding Beams - physics of e(sup +)e(sup -) and (anti p)p collisions; (2) Task C: MACRO Experiment - search for magnetic monopoles and study of cosmic rays; (3) Task D: Proton Decay - search for nucleon instability and study of neutrino interactions; (4) Tasks E, J, and N: Particle Theory - theoretical high energy particle physics, including two Outstanding Junior Investigator awards; (5) Task F: Muon G-2 - measurement of the anomalous magnetic moment of the muon; (6) Task K: SSCintcal - calorimetry for the GEM Experiment; (7) Task L: Muon Detectors for the GEM Experiment. The body of the proposal is devoted to detailed discussions of each of the tasks. The total budget request for the program appears in a summary chapter that includes a general budget discussion and individual budget requests and explanations for each of the tasks.

  14. Astrobiology at Arizona State University: An Overview of Accomplishments

    NASA Technical Reports Server (NTRS)

    Farmer, Jack

    2005-01-01

    During our five years as an NAI charter member, Arizona State University sponsored a broadly-based program of research and training in Astrobiology to address the origin, evolution and distribution of life in the Solar System. With such a large, diverse and active team, it is not possible in a reasonable space, to cover all details of progress made over the entire five years. The following paragraphs provide an overview update of the specific research areas pursued by the Arizona State University (ASU) Astrobiology team at the end of Year 5 and at the end of the 4 month and subsequent no cost month extensions. for a more detailed review, the reader is referred to the individual annual reports (and Executive Summaries) submitted to the NAI at the end of each of our five years of membership. Appended in electronic form is our complete publication record for all five years, plus a tabulation of undergraduates, graduate students and post-docs supported by our program during this time. The overarching theme of ASU s Astrobiology program was "Exploring the Living Universe: Studies of the Origin, Evolution and Distribution of Life in the Solar System". The NAi-funded research effort was organized under three basic sub- themes: 1. Origins of the Basic Building Blocks of Life. 2. Early Biosphere Evolution. and 3. Exploring for Life in the Solar System. These sub-theme areas were in turn, subdivided into Co-lead research modules. In the paragraphs that follow, accomplishments for individual research modules are briefly outlined, and the key participants presented in tabular form. As noted, publications for each module are appended in hard copy and digital formats, under the name(s) of lead co-Is.

  15. Life paths and accomplishments of mathematically precocious males and females four decades later.

    PubMed

    Lubinski, David; Benbow, Camilla P; Kell, Harrison J

    2014-12-01

    Two cohorts of intellectually talented 13-year-olds were identified in the 1970s (1972-1974 and 1976-1978) as being in the top 1% of mathematical reasoning ability (1,037 males, 613 females). About four decades later, data on their careers, accomplishments, psychological well-being, families, and life preferences and priorities were collected. Their accomplishments far exceeded base-rate expectations: Across the two cohorts, 4.1% had earned tenure at a major research university, 2.3% were top executives at "name brand" or Fortune 500 companies, and 2.4% were attorneys at major firms or organizations; participants had published 85 books and 7,572 refereed articles, secured 681 patents, and amassed $358 million in grants. For both males and females, mathematical precocity early in life predicts later creative contributions and leadership in critical occupational roles. On average, males had incomes much greater than their spouses', whereas females had incomes slightly lower than their spouses'. Salient sex differences that paralleled the differential career outcomes of the male and female participants were found in lifestyle preferences and priorities and in time allocation. PMID:25384550

  16. An Evaluation of State Energy Program Accomplishments: 2002 Program Year

    SciTech Connect

    Schweitzer, M.

    2005-07-13

    SEP activities performed by the states during the 2002 program year, based on primary data provided by the states themselves. This is the second systematic evaluation of SEP accomplishments performed by Oak Ridge National Laboratory (ORNL) for DOE. A report documenting the findings of the first study was published in January 2003 (Schweitzer et.al., 2003).

  17. Affordability as a discursive accomplishment in a changing National Health Service.

    PubMed

    Russell, Jill; Greenhalgh, Trisha

    2012-12-01

    Health systems worldwide face the challenges of rationing. The English National Health Service (NHS) was founded on three core principles: universality, comprehensiveness, and free at the point of delivery. Yet patients are increasingly hearing that some treatments are unaffordable on the NHS. We considered affordability as a social accomplishment and sought to explore how those charged with allocating NHS resources achieved this in practice. We undertook a linguistic ethnography to examine the work practices of resource allocation committees in three Primary Care Trusts (PCTs) in England between 2005 and 2012, specifically deliberations over 'individual funding requests' (IFRs)--requests by patients and their doctors for the PCT to support a treatment not routinely funded. We collected and analysed a diverse dataset comprising policy documents, legal judgements, audio recordings, ethnographic field notes and emails from PCT committee meetings, interviews and a focus group with committee members. We found that the fundamental values of universality and comprehensiveness strongly influenced the culture of these NHS organisations, and that in this context, accomplishing affordability was not easy. Four discursive practices served to confer legitimacy on affordability as a guiding value of NHS health care: (1) categorising certain treatments as only eligible for NHS funding if patients could prove 'exceptional' circumstances; (2) representing resource allocation decisions as being not (primarily) about money; (3) indexical labelling of affordability as an ethical principle, and (4) recontextualising legal judgements supporting refusal of NHS treatment on affordability grounds as 'rational'. The overall effect of these discursive practices was that denying treatment to patients became reasonable and rational for an organisation even while it continued to espouse traditional NHS values. We conclude that deliberations about the funding of treatments at the margins of NHS

  18. Nineteen hundred seventy three significant accomplishments. [Landsat satellite data applications

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Data collected by the Skylab remote sensing satellites was used to develop applications techniques and to combine automatic data classification with statistical clustering methods. Continuing research was concentrated in the correlation and registration of data products and in the definition of the atmospheric effects on remote sensing. The causes of errors encountered in the automated classification of agricultural data are identified. Other applications in forestry, geography, environmental geology, and land use are discussed.

  19. Space Shuttle Program Primary Avionics Software System (PASS) Success Legacy -Major Accomplishments and Lessons Learned

    NASA Technical Reports Server (NTRS)

    Orr, James K.

    2010-01-01

    This presentation has shown the accomplishments of the PASS project over three decades and highlighted the lessons learned. Over the entire time, our goal has been to continuously improve our process, implement automation for both quality and increased productivity, and identify and remove all defects due to prior execution of a flawed process in addition to improving our processes following identification of significant process escapes. Morale and workforce instability have been issues, most significantly during 1993 to 1998 (period of consolidation in aerospace industry). The PASS project has also consulted with others, including the Software Engineering Institute, so as to be an early evaluator, adopter, and adapter of state-of-the-art software engineering innovations.

  20. Use of qualitative integrative cycler PCR (qicPCR) to identify optimal therapeutic dosing time-points in a Respiratory Syncytial Virus Human Viral Challenge Model (hVCM).

    PubMed

    Kelly, Geraldine; Laxton, Carl; Garelnabi, Mariam; Alton, Brian; Addan, Fatima; Catchpole, Andrew; Thomas, Elaine; Borley, Daryl; Dee, Kieran; Boyers, Alison; Bringas, Erica; Noulin, Nicolas; Lambkin-Williams, Rob; Murray, Edward J

    2015-11-01

    Retroscreen (hVIVO) have developed an RSV human viral challenge model (hVCM) for testing the efficacy of novel antiviral therapies by monitoring changes in viral load and symptoms. The integrated cycler technology and Simplexa™ kits (Focus Diagnostics) currently provide fast, qualitative and sensitive diagnostic testing in hospitals and other healthcare facilities for patients with well-established respiratory illness. We have developed a novel use of qualitative integrated cycler PCR (qicPCR) technology to identify onset of RSV infection enabling an informed dosing clinical protocol in the RSV hVCM. We have validated qicPCR detection of RSV in spiked nasal wash aspirates and demonstrate that the qicPCR assay is 94% concordant with RSV plaque assay data in nasal wash samples from 53 RSV inoculated human volunteers in the hVCM. The use of qicPCR for informed dosing was successfully implemented in a recent clinical trial demonstrating efficacy of the RSV entry inhibitor GS-5806 in the hVCM (NCT01756482). Comparison of qicPCR positivity in relation to nasal wash viral load measured by both RT-qPCR and plaque assay shows that the therapeutic exposure was correctly initiated prior to onset and peak of RSV viral shedding and symptoms in the majority of volunteers. PMID:26335961

  1. An Overview of SIMBIOS Program Activities and Accomplishments. Chapter 1

    NASA Technical Reports Server (NTRS)

    Fargion, Giulietta S.; McClain, Charles R.

    2003-01-01

    The SIMBIOS Program was conceived in 1994 as a result of a NASA management review of the agency's strategy for monitoring the bio-optical properties of the global ocean through space-based ocean color remote sensing. At that time, the NASA ocean color flight manifest included two data buy missions, the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) and Earth Observing System (EOS) Color, and three sensors, two Moderate Resolution Imaging Spectroradiometers (MODIS) and the Multi-angle Imaging Spectro-Radiometer (MISR), scheduled for flight on the EOS-Terra and EOS-Aqua satellites. The review led to a decision that the international assemblage of ocean color satellite systems provided ample redundancy to assure continuous global coverage, with no need for the EOS Color mission. At the same time, it was noted that non-trivial technical difficulties attended the challenge (and opportunity) of combining ocean color data from this array of independent satellite systems to form consistent and accurate global bio-optical time series products. Thus, it was announced at the October 1994 EOS Interdisciplinary Working Group meeting that some of the resources budgeted for EOS Color should be redirected into an intercalibration and validation program (McClain et al., 2002).

  2. What the Philosophical Interpretation of Quantum Theory Can Accomplish

    NASA Astrophysics Data System (ADS)

    Carrier, Martin

    I argue that philosophical reflection can contribute to a better understanding of physical theories by performing conceptual clarification, epistemological analysis and ontological exploration. I begin by reconstructing early ontological interpretations of quantum theory, i.e., by explaining Copenhagen instrumentalism and the shift toward a quantum realism. I turn to entanglement, whose chief philosophical challenge is to understand which deeper property of nature it reveals. The trouble is that the EPR-correlations it gives rise to are not produced by common causation. Conceptual analysis shows that this failure is due to the violation of separability in quantum theory. In entangled states, it is the composite state that is primary since it cannot be neatly divided into two states that unambiguously pertain to the partial systems. As a result, total states are not produced by an interaction among the parts. This feature can be interpreted in ontological terms as suggesting a holist picture of nature. Another question of philosophical import concerns the quantum measurement problem and the contribution decoherence makes to its solution. The conceptual point is what, precisely, this problem amounts to and what we require considering it settled. The issue that divides the philosophical factions is whether a solution needs to show that superpositions are actually destroyed or whether it suffices to demonstrate that superpositions become unobservable.

  3. The Speeding Car Design Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2009-01-01

    All too often, one reads about high-speed police chases in pursuit of stolen cars that result in death and injury to people and innocent bystanders. Isn't there another way to accomplish the apprehension of the thieves that does not put people at such great risk? This article presents a classroom challenge to use technology to remotely shutdown…

  4. Accomplishments in Bioastronautics Research Aboard International Space Station

    NASA Technical Reports Server (NTRS)

    Uri, John J.

    2003-01-01

    The seventh long-duration expedition crew is currently in residence aboard International Space Station (ISS), continuing a permanent human presence in space that began in October 2000. During that time, expedition crews have been operators and subjects for 16 Human Life Sciences investigations, to gain a better understanding of the effects of long-duration space flight on the crew members and of the environment in which they live. Investigations have been conducted to study the radiation environment in the station as well as during extravehicular activity (EVA); bone demineralization and muscle deconditioning; changes in neuromuscular reflexes, muscle forces and postflight mobility; causes and possible treatment of postflight orthostatic intolerance; risk of developing kidney stones; changes in pulmonary function caused by long-duration flight as well as EVA; crew and crew-ground interactions; and changes in immune function. The experiment mix has included some conducted in flight aboard ISS as well as several which collected data only pre- and postflight. The conduct of these investigations has been facilitated by the Human Research Facility (HRF). HRF Rack 1 became the first research rack on ISS when it was installed in the US laboratory module Destiny in March 2001. The rack provides a core set of experiment hardware to support investigations, as well as power, data and commanding capability, and stowage. The second HRF rack, to complement the first with additional hardware and stowage capability, will be launched once Shuttle flights resume. Future years will see additional capability to conduct human research on ISS as International Partner modules and facility racks are added to ISS . Crew availability, both as a subject count and time, will remain a major challenge to maximizing the science return from the bioastronautics research program.

  5. Accomplishments in bioastronautics research aboard International Space Station.

    PubMed

    Uri, John J; Haven, Cynthia P

    2005-01-01

    The tenth long-duration expedition crew is currently in residence aboard International Space Station (ISS), continuing a permanent human presence in space that began in October 2000. During that time, expedition crews have been operators and subjects for 18 Human Life Sciences investigations, to gain a better understanding of the effects of long-duration spaceflight on the crewmembers and of the environment in which they live. Investigations have been conducted to study: the radiation environment in the station as well as during extravehicular activity (EVA); bone demineralization and muscle deconditioning; changes in neuromuscular reflexes; muscle forces and postflight mobility; causes and possible treatment of postflight orthostatic intolerance; risk of developing kidney stones; changes in pulmonary function caused by long-duration flight as well as EVA; crew and crew-ground interactions; changes in immune function, and evaluation of imaging techniques. The experiment mix has included some conducted in flight aboard ISS as well as several which collected data only pre- and postflight. The conduct of these investigations has been facilitated by the Human Research Facility (HRF). HRF Rack 1 became the first research rack on ISS when it was installed in the US laboratory module Destiny in March 2001. The rack provides a core set of experiment hardware to support investigations, as well as power, data and commanding capability, and stowage. The second HRF rack, to complement the first with additional hardware and stowage capability, will be launched once Shuttle flights resume. Future years will see additional capability to conduct human research on ISS as International Partner modules and facility racks are added to ISS. Crew availability, both as a subject count and time, will remain a major challenge to maximizing the science return from the bioastronautics research program. PMID:15835037

  6. Accomplishments in bioastronautics research aboard International Space Station

    NASA Astrophysics Data System (ADS)

    Uri, John J.; Haven, Cynthia P.

    2005-05-01

    The tenth long-duration expedition crew is currently in residence aboard International Space Station (ISS), continuing a permanent human presence in space that began in October 2000. During that time, expedition crews have been operators and subjects for 18 Human Life Sciences investigations, to gain a better understanding of the effects of long-duration space flight on the crewmembers and of the environment in which they live. Investigations have been conducted to study: the radiation environment in the station as well as during extravehicular activity (EVA); bone demineralization and muscle deconditioning; changes in neuromuscular reflexes; muscle forces and postflight mobility; causes and possible treatment of postflight orthostatic intolerance; risk of developing kidney stones; changes in pulmonary function caused by long-duration flight as well as EVA; crew and crew-ground interactions; changes in immune function, and evaluation of imaging techniques. The experiment mix has included some conducted in flight aboard ISS as well as several which collected data only pre- and postflight. The conduct of these investigations has been facilitated by the Human Research Facility (HRF). HRF Rack 1 became the first research rack on ISS when it was installed in the US laboratory module Destiny in March 2001. The rack provides a core set of experiment hardware to support investigations, as well as power, data and commanding capability, and stowage. The second HRF rack, to complement the first with additional hardware and stowage capability, will be launched once Shuttle flights resume. Future years will see additional capability to conduct human research on ISS as International Partner modules and facility racks are added to ISS. Crew availability, both as a subject count and time, will remain a major challenge to maximizing the science return from the bioastronautics research program.

  7. Pyrimidine homeostasis is accomplished by directed overflow metabolism

    PubMed Central

    Reaves, Marshall Louis; Young, Brian D.; Hosios, Aaron M.; Xu, Yi-Fan; Rabinowitz, Joshua D.

    2015-01-01

    Cellular metabolism converts available nutrients into usable energy and biomass precursors. The process is regulated to facilitate efficient nutrient use and metabolic homeostasis. Feedback inhibition of the first committed step of a pathway by its final product is a classical means of controlling biosynthesis1–4. In a canonical example, the first committed enzyme in the pyrimidine pathway in Escherichia coli is allosterically inhibited by cytidine triphosphate1,4,5. The physiological consequences of disrupting this regulation, however, have not been previously explored. Here we identify an alternative regulatory strategy that enables precise control of pyrimidine pathway end-product levels, even in the presence of dysregulated biosynthetic flux. The mechanism involves cooperative feedback regulation of the near-terminal pathway enzyme uridine monophosphate kinase6. Such feedback leads to build-up of the pathway intermediate uridine monophosphate, which is in turn degraded by a conserved phosphatase, here termed UmpH, with previously unknown physiological function7,8. Such directed overflow metabolism allows homeostasis of uridine triphosphate and cytidine triphosphate levels at the expense of uracil excretion and slower growth during energy limitation. Disruption of the directed overflow regulatory mechanism impairs growth in pyrimidine-rich environments. Thus, pyrimidine homeostasis involves dual regulatory strategies, with classical feedback inhibition enhancing metabolic efficiency and directed overflow metabolism ensuring end-product homeostasis. PMID:23903661

  8. How should HMOs measure their efforts and accomplishments?

    PubMed

    Probst, F R

    1988-03-01

    Accounting procedures among prepaid healthcare plans vary considerably, so much so that the accounting profession is considering what should be appropriate practice. Some standardarization is needed because of wide variations in measuring performance. This can be an obstacle in discussions of whether HMOs are more efficient than other delivery systems and what type of HMO is most successful. Healthcare expenses can be recognized at the time of payment, at the time they are reported to the plan, at the time services are provided, or in anticipation of future services. The accounting profession has identified four HMO models to determine whether organizational structure should affect financial reporting. The models, which differ in the relationship between the HMO and enrolled members and physicians, are staff model, group model, individual practice association, and network model. The accountants reject recognizing expense at the time of payment because it does not conform to generally accepted accounting principles. They suggest two alternatives: recognizing expense when the service is provided, or recognizing as expense, on the date of initial service, the expected cost of all anticipated services required by the diagnosis. The former approach appears preferable because of its consistency with the way healthcare services are delivered and the logic of accounting theory. PMID:10286251

  9. U.S. Spacesuit Knowledge Capture Accomplishments in Fiscal Years 2012 and 2013

    NASA Technical Reports Server (NTRS)

    Chullen, Cinda; Oliva, Vladenka R.

    2014-01-01

    The NASA U.S. spacesuit knowledge capture (KC) program has been in operations since the beginning 2008. The program was designed to augment engineers and others with information about spacesuits in a historical way. A multitude of seminars have captured spacesuit history and knowledge over the last six years of the programs existence. Subject matter experts have provided lectures and were interviewed to help bring the spacesuit to life so that lessons learned will never be lost. As well, the program concentrated in reaching out to the public and industry by making the recorded events part of the public domain through the NASA technical library via You Tube media. The U.S. spacesuit KC topics have included lessons learned from some of the most prominent spacesuit experts and spacesuit users including current and former astronauts. The events have enriched the spacesuit legacy knowledge from Gemini, Apollo, Skylab, Space Shuttle and International Space Station Programs. As well, expert engineers and scientists have shared their challenges and successes to be remembered. The last few years have been some of the most successful years of the KC program program's life with numerous recordings and releases to the public. It is evidenced by the thousands that have view the recordings online. This paper reviews the events accomplished and archived over Fiscal Years 2012 and 2013 and highlights a few of the most memorable ones. This paper also communicates ways to access the events that are available internally to NASA as well as in the public domain.

  10. Accomplishments in free-piston stirling tests at NASA GRC

    NASA Astrophysics Data System (ADS)

    Schreiber, Jeffrey G.; Skupinski, Robert C.

    2002-01-01

    A power system based on the Stirling Radioisotope Generator (SRG) has been identified for potential use on deep space missions, as well as for Mars rovers that may benefit from extended operation. The Department of Energy (DOE) has responsibility for developing the generator and the NASA Glenn Research Center (GRC) is supporting DOE in this effort. The generator is based on a free-piston Stirling power convertor that has been developed by the Stirling Technology Company (STC) under contract to DOE. The generator would be used as a high-efficiency alternative to the Radioisotope Thermoelectric Generators (RTGs) that have been used on many previous missions. The increased efficiency leads to a factor of 3 to 4 reduction in the inventory of plutonium required to heat the generator. GRC has been involved in the development of Stirling power conversion technology for over 25 years. The support provided to this project by GRC has many facets and draws upon the lab's scientists and engineers that have gained experience in applying their skills to the previous Stirling projects. This has created a staff with an understanding of the subtleties involved in applying their expertise to Stirling systems. Areas include materials, structures, tribology, controls, electromagnetic interference, permanent magnets, alternator analysis, structural dynamics, and cycle performance. One of the key areas of support to the project is in the performance testing of the free-piston Stirling convertors. Since these power convertors are the smallest, lowest power Stirling machines that have been tested at GRC, a new laboratory was equipped for this project. Procedures and test plans have been created, instrumentation and data systems developed, and Stirling convertors have been tested. This paper will describe the GRC test facility, the test procedures that are used, present some of the test results and outline plans for the future. .

  11. Inspiring the Next Generation: The International Space Station Education Accomplishments

    NASA Technical Reports Server (NTRS)

    Alleyne, Camille W.; Hasbrook, Pete; Knowles, Carolyn; Chicoine, Ruth Ann; Miyagawa, Yayoi; Koyama, Masato; Savage, Nigel; Zell, Martin; Biryukova, Nataliya; Pinchuk, Vladimir; Odelevsky, Vladimir; Firsyuk, Sergey; Alifanov, Oleg

    2014-01-01

    The International Space Station (ISS) has a unique ability to capture the imagination of both students and teachers worldwide. Since 2000, the presence of humans onboard ISS has provided a foundation for numerous educational activities aimed at capturing that interest and motivating study in the sciences, technology, engineering and mathematics (STEM). Over 43 million students around the world have participated in ISS-related educational activities. Projects such as YouTube Space Lab, Sally Ride Earth Knowledge-based Acquired by Middle Schools (EarthKAM), SPHERES (Synchronized Position Hold Engage and Reorient Experimental Satellites) Zero-Robotics, Tomatosphere, and MAI-75 events among others have allowed for global student, teacher and public access to space through student classroom investigations and real-time audio and video contacts with crewmembers. Educational activities are not limited to STEM but encompass all aspects of the human condition. This is well illustrated in the Uchu Renshi project, a chain poem initiated by an astronaut while in space and continued and completed by people on Earth. With ISS operations now extended to 2024, projects like these and their accompanying educational materials are available to more students around the world. From very early on in the program's history, students have been provided with a unique opportunity to get involved and participate in science and engineering projects. Many of these projects support inquiry-based learning that allows students to ask questions, develop hypothesis-derived experiments, obtain supporting evidence and identify solutions or explanations. This approach to learning is well-published as one of the most effective ways to inspire students to pursue careers in scientific and technology fields. Ever since the first space station element was launched, a wide range of student experiments and educational activities have been performed, both individually and collaboratively, by all the

  12. Some innovations and accomplishments of Ames Research Center since its inception

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The innovations and accomplishments of Ames Research Center from 1940 through 1966 are summarized and illustrated. It should be noted that a number of accomplishments were begun at the NASA Dryden Flight Research Facility before that facility became part of the Ames Research Center. Such accomplishments include the first supersonic flight, the first hypersonic flight, the lunar landing research vehicle, and the first digital fly-by-wire aircraft.

  13. Materials Division research and technology accomplishments for FY 87 and plans for FY 88

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1988-01-01

    The research program of the Materials Division is presented as FY 87 accomplishments and FY 88 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material will be useful in program coordination with other government organizations, universities, and industries in areas of mutual interest.

  14. The Role of Planned Professional Learning in Becoming an Accomplished Teacher: The Queensland Experience

    ERIC Educational Resources Information Center

    Saunders, Sherryl

    2009-01-01

    The role of planned professional learning in being an accomplished languages and cultures teacher has never been so important. Professional learning that focuses on "becoming" an accomplished practitioner as part of an ongoing professional learning experience rather than a process of detailing deficiencies is to be applauded. Indeed, the…

  15. Summaries of 1984-85 NASA space-gravitational biology accomplishments

    NASA Technical Reports Server (NTRS)

    Halstead, T. W. (Compiler); Dutcher, F. R. (Compiler); Pleasant, L. G. (Compiler)

    1985-01-01

    Individual technical summaries of research projects of NASA's Space/Gravitational Biology Program are presented. The summaries for each project include a description of the research, a listing of the accomplishments, and an explanation of the significance of the accomplishments. Bibliographies for each project are also included.

  16. Working Memory and Short-Term Memory Abilities in Accomplished Multilinguals

    ERIC Educational Resources Information Center

    Biedron, Adriana; Szczepaniak, Anna

    2012-01-01

    The role of short-term memory and working memory in accomplished multilinguals was investigated. Twenty-eight accomplished multilinguals were compared to 36 mainstream philology students. The following instruments were used in the study: three memory subtests of the Wechsler Intelligence Scale (Digit Span, Digit-Symbol Coding, and Arithmetic,…

  17. The Role of "Accomplished Teachers" in Professional Learning Communities: Uncovering Practice and Enabling Leadership

    ERIC Educational Resources Information Center

    Lieberman, Ann; Mace, Desiree H. Pointer

    2009-01-01

    This paper describes the signature role played by accomplished, experienced teachers in professional learning communities, and the importance that these practitioners make their teaching public and shared. In so doing, the authors describe how accomplished practices can be shared between classrooms and between practitioners with varying levels of…

  18. Materials Division research and technical accomplishments for FY 1988 and plans for FY 1989

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1989-01-01

    The research program of the Materials Division is presented as FY-88 accomplishments and FY-89 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material is useful in program coordination with other government organizations, universities, and industry in areas of mutual interest.

  19. Teachers' Desire for Career-Long Learning: Becoming "Accomplished"--And Masterly…

    ERIC Educational Resources Information Center

    Watson, Cate; Drew, Valerie

    2015-01-01

    The "accomplished teacher" has emerged in educational policy as a term designed to capture the dispositions and skills of highly practised professionals. As such accomplishment is enacted within a current policy discourse of life-long, or career-long, professional learning which is concerned with continual self-development. This paper…

  20. Materials Division research and technology accomplishments for FY 89 and plans for FY 90

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1990-01-01

    The research program of the Materials Division is presented as FY-89 accomplishments and FY-90 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material will be useful in program coordination with other government organizations, universities, and industries in areas of mutual interest.

  1. Predicting College Student Success: A Historical and Predictive Examination of High School Activities and Accomplishments

    ERIC Educational Resources Information Center

    Davey, Carla Mae

    2010-01-01

    According to generational theorists, the interests and experiences of incoming students have fluctuated over time, with Millennial students being more engaged and accomplished than their predecessors. This project explored data from 1974-2007 to determine the actual trends in engagement and accomplishments for three generations of students. Over…

  2. Mission accomplished

    SciTech Connect

    Rhinelander, J.B.; Rubin, J.P.

    1987-09-01

    In October 1085, then Security Adviser Robert McFarlane revealed the Reagan administration's new interpretation of the 1972 ABM Treaty, namely: develop and test Star Wars up to the point of deployment. This announcement led to storms of protest from NATO allies, members of Congress, and the Soviet Union. Congressional debate over the last two years, led by Senator Sam Nunn, demonstrated conclusively that when the Senate, by a vote of 88-2, gave its advice and consent to ratification in 1972, it did so on the basis of the traditional interpretation. The Reagan administration rested their case for the new interpretation primarily on their review of the treaty's negotiating record. One of the authors of this article (Rhinelander) was a legal adviser to the SALT I delegation. He and Rubin recently examined declassified portions of the negotiating record. Their findings are explicated here, with the conclusion reinforcing what all negotiators except Paul Nitze have said, namely: the traditional interpretation is irrefutably the one negotiated and agreed upon by both parties in 1972. They find the administration position extremely puzzling since the reinterpretation is not even necessary to continue a robust SDI program, which Nunn and other congressional leaders support.

  3. Dewey's Challenge to Teachers

    ERIC Educational Resources Information Center

    Fishman, Stephen M.; McCarthy, Lucille

    2010-01-01

    Given the serious social problems confronting Americans and others worldwide, the authors propose that Dewey's 1932 challenge to teachers is worthy of reconsideration by educators at all levels. In times similar to our own, Dewey challenged teachers to cultivate students' capacities to identify their happiness with what they can do to improve the…

  4. U.S. Spacesuit Knowledge Capture Accomplishments in Fiscal Years 2012 and 2013

    NASA Technical Reports Server (NTRS)

    Chullen, Cinda; Oliva, Vladenka R.

    2014-01-01

    The NASA U.S. Spacesuit Knowledge Capture (KC) program has existed since the beginning of 2008. The program was designed to augment engineers and other technical team members with historical spacesuit information to add to their understanding of the spacesuit, its evolution, its limitations, and its capabilities. Over 40 seminars have captured spacesuit history and knowledge over the last six years of the program's existence. Subject matter experts have provided lectures and some were interviewed to help bring the spacesuit to life so that lessons learned will never be lost. As well, the program concentrated in reaching out to the public and industry by making the recorded events part of the public domain through the NASA technical library through YouTube media. The U.S. Spacesuit KC topics have included lessons learned from some of the most prominent spacesuit experts and spacesuit users including current and former astronauts. The events have enriched the spacesuit legacy knowledge from Gemini, Apollo, Skylab, Space Shuttle and International Space Station Programs. As well, expert engineers and scientists have shared their challenges and successes to be remembered. Based on evidence by the thousands of people who have viewed the recordings online, the last few years have been some of the most successful years of the KC program's life with numerous digital recordings and public releases. This paper reviews the events accomplished and archived over Fiscal Years 2012 and 2013 and highlights a few of the most memorable ones. This paper also communicates ways to access the events that are available internally on the NASA domain as well as those released on the public domain.

  5. Accomplishments of the Abrupt Wing Stall (AWS) Program and Future Research Requirements

    NASA Technical Reports Server (NTRS)

    Hall, Robert M.; Woodson, Shawn H.; Chambers, Joseph R.

    2003-01-01

    The Abrupt Wing Stall (AWS) Program has addressed the problem of uncommanded lateral motions, such as wing drop and wing rock, at transonic speeds. The genesis of this Program was the experience of the F/A-18E/F Program in the late 199O's, when wing drop was discovered in the heart of the maneuver envelope for the pre-production aircraft. While the F/A-18E/F problem was subsequently corrected by a leading-edge flap scheduling change and the addition of a porous door to the wing fold fairing, the AWS Program was initiated as a national response to the lack of technology readiness available at the time of the F/A-18E/F Development Program. The AWS Program objectives were to define causal factors for the F/A-18E/F experience, to gain insights into the flow physics associated with wing drop, and to develop methods and analytical tools so that future programs could identify this type of problem before going to flight test. The paper reviews, for the major goals of the AWS Program, the status of the technology before the program began, the program objectives, accomplishments, and impacts. Lessons learned are presented for the benefit of future programs that must assess whether a vehicle will have uncommanded lateral motions before going to flight test. Finally, recommended future research needs are presented in light of the AWS Program experience.

  6. Challenges in obesity research.

    PubMed

    Palou, Andreu; Bonet, M Luisa

    2013-09-01

    Obesity is the main nutritional problem and one of the most important health problems in developed societies. Central to the challenge of obesity prevention and management is a thoroughly understanding of its determinants. Multiple socio-cultural, socio-economic, behavioural and biological factors--often interrelated and many of them still unknown or poorly understood--can contribute to the establishment and perpetuation of obese phenotypes. Here, we address current research challenges regarding basic aspects of obesity and emerging science for its control, including brown adipose tissue thermogenesis and browning of white fat as possible therapeutic targets for obesity, the influence of the microbioma, and genetics, epigenetics, nutrigenomics and nutrigenetics of obesity. We also highlight hot topics in relation to food and lifestyle as determinants of obesity, including the brain mechanisms underlying environmental motivation to eat, the biological control of spontaneous physical activity, the possible role of concrete foods and food components, and the importance of early life nutrition and environment. Challenges regarding the connections of obesity with other alterations and pathologies are also briefly addressed, as well as social and economical challenges in relation to healthy food production and lifestyle for the prevention of obesity, and technological challenges in obesity research and management. The objective is to give a panoramic of advances accomplished and still ahead relevant to the different stakeholders engaged in understanding and combating obesity. PMID:24010755

  7. Serving the Nation for Fifty Years: 1952 - 2002 Lawrence Livermore National Laboratory [LLNL], Fifty Years of Accomplishments

    DOE R&D Accomplishments Database

    2002-01-01

    For 50 years, Lawrence Livermore National Laboratory has been making history and making a difference. The outstanding efforts by a dedicated work force have led to many remarkable accomplishments. Creative individuals and interdisciplinary teams at the Laboratory have sought breakthrough advances to strengthen national security and to help meet other enduring national needs. The Laboratory's rich history includes many interwoven stories -- from the first nuclear test failure to accomplishments meeting today's challenges. Many stories are tied to Livermore's national security mission, which has evolved to include ensuring the safety, security, and reliability of the nation's nuclear weapons without conducting nuclear tests and preventing the proliferation and use of weapons of mass destruction. Throughout its history and in its wide range of research activities, Livermore has achieved breakthroughs in applied and basic science, remarkable feats of engineering, and extraordinary advances in experimental and computational capabilities. From the many stories to tell, one has been selected for each year of the Laboratory's history. Together, these stories give a sense of the Laboratory -- its lasting focus on important missions, dedication to scientific and technical excellence, and drive to made the world more secure and a better place to live.

  8. Structures and Dynamics Division research and technology plans for FY 1894 and accomplishments for FY 1982

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1984-01-01

    The Objectives, Expected Results, Approach, and Fiscal Year FY 1984 Milestones for the Structures and Dynamics Division's research programs are examined. The FY 1983 Accomplishments are presented where applicable.

  9. WISM - A Wideband Instrument for Snow Measurement: Past Accomplishments, Current Status, and Path Forward

    NASA Technical Reports Server (NTRS)

    Bonds, Quenton; Racette, Paul; Durham, Tim (Principal Investigator)

    2016-01-01

    Presented are the prior accomplishments, current status and path forward for GSFC's Wideband Instrument for Snow Measurement (WISM). This work is a high level overview of the project, presented via Webinar to the IEEE young professionals.

  10. The genetics of music accomplishment: evidence for gene-environment correlation and interaction.

    PubMed

    Hambrick, David Z; Tucker-Drob, Elliot M

    2015-02-01

    Theories of skilled performance that emphasize training history, such as K. Anders Ericsson and colleagues' deliberate-practice theory, have received a great deal of recent attention in both the scientific literature and the popular press. Twin studies, however, have demonstrated evidence for moderate-to-strong genetic influences on skilled performance. Focusing on musical accomplishment in a sample of over 800 pairs of twins, we found evidence for gene-environment correlation, in the form of a genetic effect on music practice. However, only about one quarter of the genetic effect on music accomplishment was explained by this genetic effect on music practice, suggesting that genetically influenced factors other than practice contribute to individual differences in music accomplishment. We also found evidence for gene-environment interaction, such that genetic effects on music accomplishment were most pronounced among those engaging in music practice, suggesting that genetic potentials for skilled performance are most fully expressed and fostered by practice. PMID:24957535

  11. Reshaping American Energy - A Look Back at BETO's Accomplishments in 2013

    SciTech Connect

    2013-11-01

    For more than a decade, BETO has been shaping the bioenergy industry. BETO helps transform the nation's renewable biomass resources into high-performance biofuels, biopower, and bioproducts. This fact sheet outlines some of our biggest accomplishments in 2013.

  12. Structural dynamics division research and technology accomplishments for FY 1989 and plans for FY 1990

    NASA Technical Reports Server (NTRS)

    Smith, Jacqueline G.; Gardner, James E.

    1990-01-01

    The purpose is to present the Structural Dynamics Division's research accomplishments for FY 1989 and research plans for FY 1990. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  13. Structural dynamics division research and technology accomplishments for FY 1988 and plans for FY 1989

    NASA Technical Reports Server (NTRS)

    Gardner, James E.

    1989-01-01

    The purpose of this paper is to present the Structural Dynamics Division's research accomplishments for FY 1988 and research plans for FY 1989. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and plans for the current year as they relate to five-year plans for each area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  14. Structural dynamics division research and technology accomplishments for FY 1993 and plans for FY 1994

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1994-01-01

    The purpose is to present the Structural Dynamics Division's research accomplishments for F.Y. 1993 and research plans for F.Y. 1994. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  15. Loads and Aeroelasticity Division research and technology accomplishments for FY 1986 and plans for FY 1987

    NASA Technical Reports Server (NTRS)

    Gardner, James E.; Dixon, S. C.

    1987-01-01

    The Loads and Aeroelasticity Division's research accomplishments for FY 86 and research plans for FY 87 are presented. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  16. Loads and aeroelasticity division research and technology accomplishments for FY 1987 and plans for FY 1988

    NASA Technical Reports Server (NTRS)

    Dixon, S. C.; Gardner, James E.

    1988-01-01

    The purpose of this paper is to present the Loads and Aeroelasticity Division's research accomplishments for FY87 and research plans for FY88. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  17. Loads and aeroelasticity division research and technology accomplishments for FY 1985 and plans for FY 1986

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.; Dixon, S. C.

    1986-01-01

    The Langley Research Center Loads and Aeroelasticity Division's research accomplishments for FY85 and research plans for FY86 are presented. The rk under each branch (technical area) will be described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  18. Loads and Aeroelasticity Division research and technology accomplishments for FY 1984 and plans for FY 1985

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.; Dixon, S. C.

    1985-01-01

    The loads and aeroelasticity divisions research accomplishments are presented. The work under each branch or technical area, described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  19. NASA's In-Situ Resource Utilization Project: Current Accomplishments and Exciting Future Plans

    NASA Technical Reports Server (NTRS)

    Larson, William E.; Sanders, Gerald B.; Sacksteder, Kurt R.

    2010-01-01

    The utilization of Space resources has been identified in publications for over 40 years for its potential as a "game changing" technology for the human exploration of Space. It is called "game changing" because of the mass leverage possible when local resources at the exploration destination arc used to reduce or even eliminate resources that are brought from the Earth. NASA, under the Exploration Technology Development Program has made significant investments in the development of Space resource utilization technologies as a part of the In-Situ Resource Utilization (ISRU) project. Over the last four years, the ISRU project has taken what was essentially an academic topic with lots of experimentation but little engineering and produced near-full-scale systems that have been demonstrated. In 2008 & again in early 2010, systems that could produce oxygen from lunar soils (or their terrestrial analogs) were tested at a lunar analog site on a volcano in Hawaii. These demonstrations included collaborations with International Partners that made significant contributions to the tests. The proposed federal budget for Fiscal Year 2011 encourages the continued development and demonstration of ISRU. However it goes beyond what the project is currently doing and directs that the scope of the project be expanded to cover destinations throughout the inner solar system with the potential for night demonstrations. This paper will briefly cover the past accomplishments of the ISRU project then move to a di scussion of the plans for the project's future as NASA moves to explore a new paradigm for Space Exploration that includes orbital fuel depots and even refueling on other planetary bodies in the solar system.

  20. A Plan for the Next Generation of HIV Prevention Research: Seven Key Policy Investigative Challenges

    ERIC Educational Resources Information Center

    Coates, Thomas J.; Szekeres,Gregory

    2004-01-01

    Although HIV prevention research has accomplished much over the last 2 decades, significant challenges remain. The accomplishments have included rapid progression through various stages of research--from descriptive to clinical trials--and the fielding of several Phase 3 trials with biological endpoints. The challenges include developing…

  1. Reusable Solid Rocket Motor - Accomplishment, Lessons, and a Culture of Success

    NASA Technical Reports Server (NTRS)

    Moore, D. R.; Phelps, W. J.

    2011-01-01

    The Reusable Solid Rocket Motor (RSRM) represents the largest solid rocket motor (SRM) ever flown and the only human-rated solid motor. High reliability of the RSRM has been the result of challenges addressed and lessons learned. Advancements have resulted by applying attention to process control, testing, and postflight through timely and thorough communication in dealing with all issues. A structured and disciplined approach was taken to identify and disposition all concerns. Careful consideration and application of alternate opinions was embraced. Focus was placed on process control, ground test programs, and postflight assessment. Process control is mandatory for an SRM, because an acceptance test of the delivered product is not feasible. The RSRM maintained both full-scale and subscale test articles, which enabled continuous improvement of design and evaluation of process control and material behavior. Additionally RSRM reliability was achieved through attention to detail in post flight assessment to observe any shift in performance. The postflight analysis and inspections provided invaluable reliability data as it enables observation of actual flight performance, most of which would not be available if the motors were not recovered. RSRM reusability offered unique opportunities to learn about the hardware. NASA is moving forward with the Space Launch System that incorporates propulsion systems that takes advantage of the heritage Shuttle and Ares solid motor programs. These unique challenges, features of the RSRM, materials and manufacturing issues, and design improvements will be discussed in the paper.

  2. The contribution of the ACCOMPLISH trial to the treatment of stage 2 hypertension.

    PubMed

    Byrd, James Brian; Bakris, George; Jamerson, Kenneth

    2014-03-01

    The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) recommended a thiazide-like diuretic, alone or in combination with other antihypertensive drug classes, as initial therapy for hypertension. JNC 7, however, did not specify preferred combinations. The Avoiding Cardiovascular Events through Combination Therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial was completed five years after the JNC 7 and demonstrated a 20 % advantage in cardiovascular risk reduction when blood pressure was lowered using the single-pill combination of benazepril-amlodipine compared to benazepril-hydrochlorothiazide (Jamerson et al. 359(23):2417-28 [1]). This new and significant finding provided compelling evidence that the long-standing preference for diuretics as initial therapy could be refuted, but it may also be relevant to the lower-than-expected reduction in coronary disease related events (compared to stroke) observed for decades prior to the ACCOMPLISH approach to therapy. The JNC 8 panel members recently published their recommendations, and while the group did not recommend benazepril-hydrochlorothiazide over other combinations, they did highlight the findings of ACCOMPLISH, rating the primary ACCOMPLISH paper as "good." The American Society of Hypertension position paper and the European Hypertension Society guidelines endorse such combinations as a first-line agent for patients with stage 2 hypertension. We review the current position of ACCOMPLISH in the guidelines regarding treatment of stage 2 hypertension. PMID:24474031

  3. Clinical challenge.

    PubMed

    2016-09-01

    Questions for this month's clinical challenge are based on articles in this issue. The clinical challenge is endorsed by the RACGP Quality Improvement and Continuing Professional Development (QI&CPD) program and has been allocated four Category 2 points (Activity ID:59922). Answers to this clinical challenge are available immediately following successful completion online at http://gplearning.racgp.org.au. Clinical challenge quizzes may be completed at any time throughout the 2014-16 triennium; therefore, the previous months' answers are not published. Each of the questions or incomplete statements below is followed by four suggested answers or completions. Select the most appropriate statement as your answer. PMID:27606376

  4. Featherweight Challenge

    ERIC Educational Resources Information Center

    Love, Tyler S.; Ryan, Larry

    2012-01-01

    As science, technology education, and engineering programs suffer budget cuts, educators continue to seek cost-effective activities that engage students and reinforce standards. The featherweight challenge is a hands-on activity that challenges students to continually refine their design while not breaking the budget. This activity uses one of the…

  5. Structural dynamics division research and technology accomplishments for FY 1992 and plans for FY 1993

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1993-01-01

    The purpose of this paper is to present the Structural Dynamics Division's research accomplishments for F.Y. 1992 and research plans for F.Y. 1993. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  6. Structural mechanics division research and technology accomplishments for CY 1992 and plans for CY 1993

    NASA Technical Reports Server (NTRS)

    Malone, John B.

    1993-01-01

    The purpose of this report is to present the Structural Mechanics Division's research accomplishments for C.Y. 1992 and plans for C.Y. 1993. The technical mission and goals of the division and its constituent research branches are described. The work under each branch is described in terms of highlights of accomplishments during the past year and plans for the current year as they relate to branch long range goals. This information is useful in program coordination with other government organizations, universities, and industry in areas of mutual interest.

  7. Innovative Partnerships Program Accomplishments: 2009-2010 at NASA's Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Makufka, David

    2010-01-01

    This document reports on the accomplishments of the Innovative Partnerships Program during the two years of 2009 and 2010. The mission of the Innovative Partnerships Program is to provide leveraged technology alternatives for mission directorates, programs, and projects through joint partnerships with industry, academia, government agencies, and national laboratories. As outlined in this accomplishments summary, the IPP at NASA's Kennedy Space Center achieves this mission via two interdependent goals: (1) Infusion: Bringing external technologies and expertise into Kennedy to benefit NASA missions, programs, and projects (2) Technology Transfer: Spinning out space program technologies to increase the benefits for the nation's economy and humanity

  8. System Engineering and Technical Challenges Overcome in the J-2X Rocket Engine Development Project

    NASA Technical Reports Server (NTRS)

    Ballard, Richard O.

    2012-01-01

    Beginning in 2006, NASA initiated the J-2X engine development effort to develop an upper stage propulsion system to enable the achievement of the primary objectives of the Constellation program (CxP): provide continued access to the International Space Station following the retirement of the Space Station and return humans to the moon. The J-2X system requirements identified to accomplish this were very challenging and the time expended over the five years following the beginning of the J- 2X effort have been noteworthy in the development of innovations in both the fields for liquid rocket propulsion and system engineering.

  9. School-Turnaround Call Points Up Challenges

    ERIC Educational Resources Information Center

    Gewertz, Catherine

    2009-01-01

    The U.S. secretary of education's call to "turn around" the nation's 5,000 worst-performing schools has found a warm welcome among educators and policy makers who see that focus as long overdue. But it has also sparked debate about how--and whether--such an enormous leadership and management challenge can be accomplished. U.S. Secretary of…

  10. International space station accomplishments update: Scientific discovery, advancing future exploration, and benefits brought home to earth

    NASA Astrophysics Data System (ADS)

    Thumm, Tracy; Robinson, Julie A.; Alleyne, Camille; Hasbrook, Pete; Mayo, Susan; Buckley, Nicole; Johnson-Green, Perry; Karabadzhak, George; Kamigaichi, Shigeki; Umemura, Sayaka; Sorokin, Igor V.; Zell, Martin; Istasse, Eric; Sabbagh, Jean; Pignataro, Salvatore

    2014-10-01

    Throughout the history of the International Space Station (ISS), crews on board have conducted a variety of scientific research and educational activities. Well into the second year of full utilization of the ISS laboratory, the trend of scientific accomplishments and educational opportunities continues to grow. More than 1500 investigations have been conducted on the ISS since the first module launched in 1998, with over 700 scientific publications. The ISS provides a unique environment for research, international collaboration and educational activities that benefit humankind. This paper will provide an up to date summary of key investigations, facilities, publications, and benefits from ISS research that have developed over the past year. Discoveries in human physiology and nutrition have enabled astronauts to return from ISS with little bone loss, even as scientists seek to better understand the new puzzle of “ocular syndrome” affecting the vision of up to half of astronauts. The geneLAB campaign will unify life sciences investigations to seek genomic, proteomic and metabolomics of the effect of microgravity on life as a whole. Combustion scientists identified a new “cold flame” phenomenon that has the potential to improve models of efficient combustion back on Earth. A significant number of instruments in Earth remote sensing and astrophysics are providing new access to data or nearing completion for launch, making ISS a significant platform for understanding of the Earth system and the universe. In addition to multidisciplinary research, the ISS partnership conducts a myriad of student led research investigations and educational activities aimed at increasing student interest in science, technology, engineering and mathematics (STEM). Over the past year, the ISS partnership compiled new statistics of the educational impact of the ISS on students around the world. More than 43 million students, from kindergarten to graduate school, with more than 28

  11. International Space Station Accomplishments Update: Scientific Discovery, Advancing Future Exploration, and Benefits Brought Home to Earth

    NASA Technical Reports Server (NTRS)

    Thumm, Tracy; Robinson, Julie A.; Alleyne, Camille; Hasbrook, Pete; Mayo, Susan; Johnson-Green, Perry; Buckley, Nicole; Karabadzhak, George; Kamigaichi, Shigeki; Umemura, Sayaka; Sorokin, Igor V.; Zell, Martin; Istasse, Eric; Sabbagh, Jean; Pignataro, Salvatore

    2013-01-01

    Throughout the history of the International Space Station (ISS), crews on board have conducted a variety of scientific research and educational activities. Well into the second year of full utilization of the ISS laboratory, the trend of scientific accomplishments and educational opportunities continues to grow. More than 1500 investigations have been conducted on the ISS since the first module launched in 1998, with over 700 scientific publications. The ISS provides a unique environment for research, international collaboration and educational activities that benefit humankind. This paper will provide an up to date summary of key investigations, facilities, publications, and benefits from ISS research that have developed over the past year. Discoveries in human physiology and nutrition have enabled astronauts to return from ISS with little bone loss, even as scientists seek to better understand the new puzzle of "ocular syndrome" affecting the vision of up to half of astronauts. The geneLAB campaign will unify life sciences investigations to seek genomic, proteomic, and metabolomics of the effect of microgravity on life as a whole. Combustion scientists identified a new "cold flame" phenomenon that has the potential to improve models of efficient combustion back on Earth. A significant number of instruments in Earth remote sensing and astrophysics are providing new access to data or nearing completion for launch, making ISS a significant platform for understanding of the Earth system and the universe. In addition to multidisciplinary research, the ISS partnership conducts a myriad of student led research investigations and educational activities aimed at increasing student interest in science, technology, engineering and mathematics (STEM). Over the past year, the ISS partnership compiled new statistics of the educational impact of the ISS on students around the world. More than 43 million students, from kindergarten to graduate school, with more than 28 million

  12. Identifying Plant Poisoning in Livestock

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Poisonous plant intoxication is a common and often deadly problem that annually costs the livestock industry more than $340 million in the western United States alone. Despite the cost or frequency, definitively identifying or diagnosing poisoning by plants in livestock is challenging. The purpos...

  13. Skylab experiments. Volume 6: Mechanics. [Skylab program accomplishments for high school level education

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Skylab program activities are presented in a form adapted to instruction of high school students. The overall goals of the program are discussed. The specific accomplishments of the mechanics investigations are described. The subjects involved are as follows: (1) evaluation of mobility aids, (2) mass measurement devices, and (3) space guidance crew/vehicle disturbances.

  14. Accomplishments, Administrative Structure, and Activities of the Sensory Aids Evaluation and Development Center. Annual Report.

    ERIC Educational Resources Information Center

    Massachusetts Inst. of Tech., Cambridge. Sensory Aids Evaluation and Development Center.

    The report lists the staff and states the activities of the Sensory Aids Evaluation and Development Center (SAEDC). Work accomplished is reviewed, including work on the following; compiled speech output for the DOTSYS Information System; monotype reader; braille embosser; folding canes; pathsounder; Perkins brailler; evaluation of braille; speeded…

  15. Foreign and Domestic Accomplishments in Magnetic Bubble Device Technology. Computer Science & Technology.

    ERIC Educational Resources Information Center

    Warnar, Robert B. J.; Calomeris, Peter J.

    This document assesses the status of magnetic bubble technology as displayed by non-U.S. research and manufacturing facilities. Non-U.S. research and U.S. accomplishments are described while both technical and economic factors are addressed. Magnetic bubble devices are discussed whenever their application could impact future computer system…

  16. Structures and Dynamics Division research and technology plans for FY 1985 and accomplishments for FY 1984

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1985-01-01

    The objectives, FY 1985 plans, approach, and FY 1985 milestones for the Structures and Dynamics Division's research programs are presented. The FY 1984 accomplishments are presented where applicable. This information is useful in program coordination with other government organizations in areas of mutual interest.

  17. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  18. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  19. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  20. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  1. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  2. Structures and Dynamics Division research and technology plans for FY 1986 and accomplishments for FY 1985

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1986-01-01

    Presented are the Objectives, FY 1986 Plans, Approach, and FY 1986 Milestones for the Structures and Dynamics Division's research programs. FY 1985 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  3. DOE-NREL Minority University Research Associates Program FY 2005 Accomplishments

    SciTech Connect

    Eddy, F. P.

    2005-11-01

    The DOE-NREL Minority University Research Associates (MURA) Program encourages minority students to pursue careers in science and technology. In 2003, eight minority-serving institutions were awarded 3-year subcontracts that began in the summer/fall of FY 2004. This paper lists accomplishments made in the project's first phase.

  4. Accomplishing Marginalization in Bilingual Interaction: Relational Work as a Resource for the Intersubjective Construction of Identity

    ERIC Educational Resources Information Center

    Cashman, Holly R.

    2008-01-01

    This paper examines the use of impoliteness by Spanish-English bilingual pre-adolescents as a resource for accomplishing identities in spontaneous conversational interactions in an elementary school setting. The theoretical approach employed integrates the concept of relational work (Locher 2004; Locher and Watts 2005), which is based on Goffman's…

  5. Structural Mechanics Division research and technology plans for FY 1990 and accomplishments for FY 1989

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1990-01-01

    The Objectives, FY 1990 Plans, Approach, and FY 1990 Milestones for the Structural Mechanics Division's research programs are presented. FY 1989 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  6. Structures and Dynamics Division research and technology plans for FY 1987 and accomplishments for FY 1986

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1987-01-01

    This paper presents the Objectives, FY 1987 Plans, Approach, and FY 1987 Milestones for the Structures and Dynamics Division's research programs. FY 1986 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  7. Research and technology plans for FY 1989 and accomplishments for FY 1988. [Structural Mechanics Division

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1989-01-01

    The Objectives, FY 1989 Plans, Approach, and FY 1989 Milestones for the Structural Mechanics Division's research programs are presented. Fiscal year 1988 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  8. A Framework for the Preparation of Accomplished Career and Technical Education Teachers

    ERIC Educational Resources Information Center

    Adams, Elaine

    2010-01-01

    Reforms in teacher preparation continue to spark national interest. In a statewide reform effort to improve teacher quality in Georgia, the State Department of Education, Board of Regents, and Professional Standards Commission have all adopted the Georgia Framework for Accomplished Teaching (Georgia Department of Education, 2003.). The Georgia…

  9. Reconstituting the ADHD Girl: Accomplishing Exclusion and Solidifying a Biomedical Identity in an ADHD Class

    ERIC Educational Resources Information Center

    Hjörne, Eva; Evaldsson, Ann-Carita

    2015-01-01

    In this study, we explore what happens to young people labelled as having attention deficit hyperactivity disorder (ADHD) after they have been excluded from mainstream class and placed in a special class. More specifically, we focus on how a specific disability identity is locally accomplished and ascribed to a girl placed in an ADHD class…

  10. Longitudinal Pathways from Math Intrinsic Motivation and Achievement to Math Course Accomplishments and Educational Attainment

    ERIC Educational Resources Information Center

    Gottfried, Adele Eskeles; Marcoulides, George A.; Gottfried, Allen W.; Oliver, Pamella H.

    2013-01-01

    Across 20 years, pathways from math intrinsic motivation and achievement (ages 9-17) to high school math course accomplishments and educational attainment (age 29) were analyzed. Academic intrinsic motivation was the theoretical foundation. To determine how initial status and change in motivation and achievement related to course accomplishments…

  11. NREL PV Module Reliability and Performance R&D Status and Accomplishments

    SciTech Connect

    Osterwald, C. R.

    2005-01-01

    This paper presents a brief overview of the status and accomplishments during Fiscal Year (FY)2004 of the Photovoltaic (PV) Module Reliability and Performance R&D Subtask, which is part of the PV Module Reliability R&D Project (a joint NREL-Sandia project).

  12. Investigating Essential Factors on Students' Perceived Accomplishment and Enjoyment and Intention to Learn in Web Development

    ERIC Educational Resources Information Center

    Zhang, Yulei; Dang, Yan

    2015-01-01

    Web development is an important component in the curriculum of computer science and information systems areas. However, it is generally considered difficult to learn among students. In this study,we examined factors that could influence students' perceptions of accomplishment and enjoyment and their intention to learn in the web development…

  13. Structures and Dynamics Division research and technology plans for FY 1988 and accomplishments for FY 1987

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1988-01-01

    Presented are the Objectives, FY 1988 Plans, Approach, and FY 1988 Milestones for the Structures and Dynamics Division (Langley Research Center) research programs. FY 1987 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  14. Activities and Accomplishments in Various Domains: Relationships with Creative Personality and Creative Motivation in Adolescence

    ERIC Educational Resources Information Center

    Hong, Eunsook; Peng, Yun; O'Neil, Harold F., Jr.

    2014-01-01

    This study examined relationships between five personal traits and adolescents' creative activities and accomplishments in five domains--music, visual arts, creative writing, science, and technology. Participants were 439 tenth graders (220 males and 219 females) in China. The relationships were examined using confirmatory factor analysis.…

  15. ERIC Annual Report, 2002: Summarizing the Recent Accomplishments of the Educational Resources Information Center.

    ERIC Educational Resources Information Center

    Smarte, Lynn; Starcher, Heather

    This ERIC Annual Report presents both accomplishments and historical perspectives, as 2001 marks 35 years of ERIC service in delivering educational research and information to the public. This annual report describes the developments in the database of educational literature, the growing variety of ERIC Web-based products and user services, and…

  16. 41 CFR 102-3.80 - How are minor charter amendments accomplished?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How are minor charter amendments accomplished? 102-3.80 Section 102-3.80 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL ADVISORY...

  17. 41 CFR 102-3.85 - How are major charter amendments accomplished?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How are major charter amendments accomplished? 102-3.85 Section 102-3.85 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL ADVISORY...

  18. Accomplishing the Visions for Teacher Education Programs Advocated in the "National Science Education Standards"

    ERIC Educational Resources Information Center

    Akcay, Hakan; Yager, Robert

    2010-01-01

    The purpose of this study was to investigate the advantages of an approach to instruction using current problems and issues as curriculum organizers and illustrating how teaching must change to accomplish real learning. The study sample consisted of 41 preservice science teachers (13 males and 28 females) in a model science teacher education…

  19. Technical summary of accomplishments made in preparation for the USSR barley exploratory experiment

    NASA Technical Reports Server (NTRS)

    Chapman, G. M.; Dailey, C. L.

    1982-01-01

    The highlights of the work accomplished under each subcomponent of the U.S.S.R. Barley Pilot Experiment, which is scheduled for completion in 1984, are summarized. A significant amount of developmental system implementation activity was in the final stages of preparation prior to the rescoping of project tasks. Unpublished materials which are significant to this exploratory experiment are incorporated into the appendixes.

  20. Loads and aeroelasticity division research and technology accomplishments for FY 1982 and plans for FY 1983

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.

    1983-01-01

    Accomplishments of the past year and plans for the coming year are highlighted as they relate to five year plans and the objectives of the following technical areas: aerothermal loads; multidisciplinary analysis and optimization; unsteady aerodynamics; and configuration aeroelasticity. Areas of interest include thermal protection system concepts, active control, nonlinear aeroelastic analysis, aircraft aeroelasticity, and rotorcraft aeroelasticity and vibrations.

  1. Definition and Measurement in the Affective Domain: Appreciation of Human Accomplishments.

    ERIC Educational Resources Information Center

    Campbell, Paul B.; Beers, Joan S.

    The first three levels of the taxonomy in the affective domain guided the development of two inventories--the Pennsylvania Inventory of Cultural Appreciations (PICA) for 11th graders and Things People Do (TPD) for 5th graders--to measure appreciation of human accomplishments in seven areas: politics, sciences, sports, literature, visual arts,…

  2. Assembling the "Accomplished" Teacher: The Performativity and Politics of Professional Teaching Standards

    ERIC Educational Resources Information Center

    Mulcahy, Dianne

    2011-01-01

    Set within the socio-political context of standards-based education reform, this article explores the constitutive role of teaching standards in the production of the practice and identity of the "accomplished" teacher. It contrasts two idioms for thinking about and studying these standards, the representational and the performative. Utilising the…

  3. The Perennial and the Particular Challenges of Design Education

    ERIC Educational Resources Information Center

    Ruecker, Stan

    2012-01-01

    Education in design shares with other disciplines a number of perennial challenges, including the need to transfer human culture, the choice of what parts of human culture to transfer and the decision as to what approaches work best in accomplishing that transfer. Design education also faces particular challenges, which are shared with only a few…

  4. Separations and Waste Forms Research and Development FY 2013 Accomplishments Report

    SciTech Connect

    Not Listed

    2013-12-01

    The Separations and Waste Form Campaign (SWFC) under the U.S. Department of Energy (DOE) Fuel Cycle Research and Development Program (FCRD) is responsible for developing advanced separation and waste form technologies to support the various fuel cycle options defined in the DOE Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. The fiscal year (FY) 2013 accomplishments report provides a highlight of the results of the research and development (R&D) efforts performed within SWFC in FY 2013. Each section contains a high-level overview of the activities, results, technical point of contact, applicable references, and documents produced during the fiscal year. This report briefly outlines campaign management and integration activities, but the intent of the report is to highlight the many technical accomplishments made during FY 2013.

  5. Accomplishments in 2008 in the Management of Curable Metastatic Colorectal Cancer

    PubMed Central

    Adam, René; Hoti, Emir; Folprecht, Gunnar; Benson, Al B.

    2009-01-01

    SUMMARY Overview of the Disease IncidencePrognosisCurrent Therapy Standards Colorectal Liver Metastases (CRLM) Resectable TumorsStrategies to Convert Nonresectable Liver Metastases to Resectable StatusSynchronous Colorectal Liver MetastasesPredictors of Survival After Resection of CRLMPeritoneal Carcinomatosis (PC) From Colorectal CancerColorectal Pulmonary Metastases (CRPM)Colorectal Liver Metastases With Extrahepatic DiseaseAccomplishments (or Lack of Accomplishments) During the Year Therapy New Staging SystemSystemic Chemotherapy in Resectable Liver MetastasesSystemic Chemotherapy in Nonresectable Liver MetastasesSelective Internal Radiation Therapy (SIRT)Selection of Patients for Liver ResectionRadiofrequency AblationBiomarkersWhat Needs To Be Done? Optimizing Patient CareFuture Directions Comments on ResearchObstacles to Overcome PMID:20011559

  6. Dynamics of self-regulation: How (un)accomplished goal actions affect motivation.

    PubMed

    Koo, Minjung; Fishbach, Ayelet

    2008-02-01

    Two factors increase the motivation to adhere to a goal: goal commitment and lack of goal progress. When people ask about commitment, focusing on what they have accomplished (to date) signals to them high commitment and increases motivation. Conversely, when commitment is certain and people ask about goal progress, focusing on what they have yet to accomplish (to go) signals to them lack of progress and increases motivation. Accordingly, 4 studies show that emphasizing to-date information increases goal adherence when commitment is uncertain--that is, when participants study for a relatively unimportant exam, consume luxuries, fulfill a desire, and make first-time contributions to a charity. Conversely, emphasizing to-go information increases goal adherence when commitment is certain--that is, when participants study for an important exam, consume necessities, fulfill a need, and make repeated contributions to a charity. PMID:18211171

  7. Having Fun and Accepting Challenges Are Natural Instincts: Jigsaw Puzzles to Challenge Students and Test Their Abilities While Having Fun!

    ERIC Educational Resources Information Center

    Rodenbaugh, Hanna R.; Lujan, Heidi L.; Rodenbaugh, David W.; DiCarlo, Stephen E.

    2014-01-01

    Because jigsaw puzzles are fun, and challenging, students will endure and discover that persistence and grit are rewarded. Importantly, play and fun have a biological place just like sleep and dreams. Students also feel a sense of accomplishment when they have completed a puzzle. Importantly, the reward of mastering a challenge builds confidence…

  8. FY 2006 Accomplishment Colony - "Services and Interfaces to Support Large Numbers of Processors"

    SciTech Connect

    Jones, T; Kale, L; Moreira, J; Mendes, C; Chakravorty, S; Tauferner, A; Inglett, T

    2006-06-30

    The Colony Project is developing operating system and runtime system technology to enable efficient general purpose environments on tens of thousands of processors. To accomplish this, we are investigating memory management techniques, fault management strategies, and parallel resource management schemes. Recent results show promising findings for scalable strategies based on processor virtualization, in-memory checkpointing, and parallel aware modifications to full featured operating systems.

  9. Engineering Innovations for Exploration Challenges

    NASA Technical Reports Server (NTRS)

    Dumbacher, Daniel L.

    2010-01-01

    This slide presentation reviews some of the engineering innovations requirements for the challenges of space exploration which NASA has and will be involved in. It reviews some significant successes in space transportation, exploration and science accomplished during 2009, and it reviews some of the places that are available for exploration in the near term and the specific missions that NASA has assigned to Marshall. It also reviews the project lifecycle management model, that is designed to reduce undefined, but known, risks. It also demonstrates the sustainable long-term program of block upgrades that contribute to long-term success of programs.

  10. Developmental psychopathology: concepts and challenges.

    PubMed

    Rutter, M; Sroufe, L A

    2000-01-01

    The defining features of developmental psychopathology concepts include attention to the understanding of causal processes, appreciation of the role of developmental mechanisms, and consideration of continuities and discontinuities between normality and psychopathology. Accomplishments with respect to these issues are reviewed in relation to attachment disorders, antisocial behavior, autism, depressive disorder, schizophrenia, and intellectual development. Major research challenges remain in relation to measurement issues, comorbidity, gender differences, cognitive processing, nature-nurture interplay, heterotypic continuity, continuities between normal variations and disorders, developmental programming, and therapeutic mechanisms in effective treatments. PMID:11014739

  11. Accomplishments of Aquarius: NASA's first global Sea Surface Salinity Mission: a review of the technical findings to date

    NASA Astrophysics Data System (ADS)

    Sen, Amit

    2014-10-01

    Launched 10 June 2011, the NASA's Aquarius instrument onboard the Argentine built and managed Satélite de Aplicaciones Científicas (SAC-D) has been tirelessly observing the open oceans, confirming and adding new knowledge to the not so vast measured records of our Earth's global oceans. This paper reviews the data collected over the last 3 years, it's findings, challenges and future work that is at hand for the sleepless oceanographers, hydrologists and climate scientists. Although routine data is being collected, a snapshot is presented from almost 3-years of flawless operations showing new discoveries and possibilities of lot more in the future. Repetitive calibration and validation of measurements from Aquarius continue together with comparison of the data to the existing array of Argo temperature/salinity profiling floats, measurements from the recent Salinity Processes in the Upper Ocean Regional Study (SPURS) in-situ experiment and research, and to the data collected from the European Soil Moisture Ocean Salinity (SMOS) mission. This all aids in the optimization of computer model functions to improve the basic understanding of the water cycle over the oceans and its ties to climate. The Aquarius mission operations team also has been tweaking and optimizing algorithms, reprocessing data as needed, and producing salinity movies that has never been seen before. A brief overview of the accomplishments, technical findings to date will be covered in this paper.

  12. Merits of a Locality Sample for Accomplishing Mars Exploration Goals: The First Sample Return Mission

    NASA Astrophysics Data System (ADS)

    Draper, D. S.; Bogard, D. D.; Agee, C. B.; McKay, G. A.; Jones, J. H.

    2002-05-01

    A major stumbling block to a Mars sample return (MSR) mission is the seemingly prohibitive cost of maximizing sample diversity. The use of rovers, sophisticated on-board instrumentation, and various sample selection techniques are perceived by some to be necessary to maximize the scientific return by making it possible to acquire as diverse a suite of samples as possible. Here, we argue that many key science goals of the Mars Exploration Program may be accomplished by returning only a "locality sample" at a well-chosen landing site. A locality sample would be local regolith consisting of soil, windblown fines, and lithic fragments (plus Martian atmosphere). We argue that even the simplest sample return mission could revolutionize our understanding of the planet, without requiring the large outlays for technology development currently envisioned. By the time a MSR mission could realistically be flown, it is reasonable to expect that information from the Mars Odyssey, Mars Express, 2003 Mars Exploration Rovers, and 2005 Mars Reconnaissance Orbiter will be sufficient to make a good choice of landing site. Returned samples of Martian regolith have the potential to answer key questions of fundamental importance to the Mars Exploration Program: The search for life; understanding the role and history of water and other volatiles; helping to interpret remotely-sensed spectral data; and understanding the planet as a system. The value of such samples has been studied exhaustively for decades and detailed in publications dating back at least to 1974. A locality sample can further the search for life by identifying, among other things, trace quantities of surface organics, biogenic elements and their isotopic compositions, evidence for water in the form of hydrous minerals and/or cements, the nature of the Martian soil oxidant, trace biomarkers, and evidence for clay-forming processes. The role of water will be better understood by revealing, in addition, whether interactions

  13. Ethical Challenges

    ERIC Educational Resources Information Center

    Morris, Michael

    2004-01-01

    All evaluators face the challenge of striving to adhere to the highest possible standards of ethical conduct. Translating the AEA's Guiding Principles and the Joint Committee's Program Evaluation Standards into everyday practice, however, can be a complex, uncertain, and frustrating endeavor. Moreover, acting in an ethical fashion can require…

  14. Quill Challenge

    ERIC Educational Resources Information Center

    Stevens, Lori

    2006-01-01

    Teaching high school students the "grammar" of art--the principles and elements of art and design--while also teaching them about creativity and concept can be difficult. This author has found that combining beginning lessons in line, shape, value, texture, form, and color with projects requiring innovation and inspiration, though challenging, is…

  15. Environmental challenge

    SciTech Connect

    Conable, B.; Warford, J.; Partow, Z.; Lutz, E.; Munasinghe, M.

    1991-09-01

    The contents include the following: Development and the Environment: A Global Balance; Evolution of the World Bank's Environmental Policy; Accounting for the Environment; Public Policy and the Environment; Managing Drylands; Environmental Action Plans in Africa; Agroforestry in Sub-Saharan Africa; Irrigation and the Environmental Challenge; Curbing Pollution in Developing Countries; Global Warming and the Developing World; and The Global Environment Facility.

  16. Challenges in Replicating Interventions

    PubMed Central

    Bell, Stephanie G; Newcomer, Susan F; Bachrach, Christine; Borawski, Elaine; Jemmott, John L; Morrison, Diane; Stanton, Bonita; Tortolero, Susan; Zimmerman, Richard

    2007-01-01

    Purpose This paper describes and reflects on an effort to document, through a set of six interventions, the process of adapting effective youth risk behavior interventions for new settings. It provides insights into how this might best be accomplished. It discusses six studies funded by NIH starting in 1999. The studies were funded in response to a Request for Applications [RFA] to replicate HIV prevention interventions for youth. Researchers were to select an HIV risk reduction intervention program shown to be effective in one adolescent population and to replicate it in a new community or different adolescent population. This was to be done while systematically documenting those processes and aspects of the intervention hypothesized to be critical to the development of community-based, culturally sensitive programs. The replication was to assess the variations necessary to gain cooperation, implement a locally feasible and meaningful intervention, and evaluate the outcomes in the new setting. Methods This paper lays out the rationale for this initiative and describes the goals and the approaches to adaptation of the funded researchers. Results The paper discusses issues relevant to all interventions, those unique to replication and to these replications in particular. It then reflects on the processes and the consequences of the adaptations. It does not address the further challenges in taking a successful intervention “to scale.” Conclusions Replications of effective interventions face all of the challenges of implementation design plus additional challenges of balancing fidelity to the original intervention and sensitivity to the needs of new populations. PMID:17531757

  17. Higher Education Marketing: A Challenge.

    ERIC Educational Resources Information Center

    Canterbury, Richard

    1999-01-01

    States that similarities between education and other services may not be sufficient to conclude that services marketing methods can be easily transferred to all markets in higher education. Article identifies and discusses why higher education marketing is a particular challenge. Suggests that understanding these challenges can help in making…

  18. Innovation and Consumer Directed Care: Identifying the challenges.

    PubMed

    Gill, Liz; Cameron, Ian D

    2015-12-01

    Our aim was to report clinician and researcher observations about the practical difficulties with achieving the articulated objectives of Consumer Directed Care (CDC). The methods used were as follows: identification of key client community services issues through analysis of qualitative data related to a PhD project; review of the summary of these issues by the supervising academic; presentation of the issues to five clinicians involved with a community service clinical trial; verification of the findings through discussions with a senior community service provider. There is anecdotal evidence that the current overlay of CDC in the existing community-based home services sector for people who are older will continue to prevent its effective implementation. The existing culture and underlying philosophies related to this sector maybe unable to support the level of innovative change required. Research is needed into how the stated objectives of CDC can be achieved in Australia and how this can best be managed. PMID:26643231

  19. Overview and Recent Accomplishments of Advanced Mirror Technology Development Phase 2 (AMTD-2)

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2015-01-01

    AMTD uses a science-driven systems engineering approach to define & execute a long-term strategy to mature technologies necessary to enable future large aperture space telescopes. Because we cannot predict the future, we are pursuing multiple technology paths including monolithic & segmented mirrors. Assembled outstanding team from academia, industry & government; experts in science & space telescope engineering. Derived engineering specifications from science measurement needs & implementation constraints. Maturing 6 critical technologies required to enable 4 to 8 meter UVOIR space telescope mirror assemblies for both general astrophysics & ultra-high contrast exoplanet imaging. AMTD achieving all its goals & accomplishing all its milestones.

  20. The Solar Thermal Design Assistance Center report of its activities and accomplishments in Fiscal Year 1993

    SciTech Connect

    Menicucci, D.F.

    1994-03-01

    The Solar Thermal Design Assistance Center (STDAC) at Sandia National Laboratories is a resource provided by the US Department of Energy`s Solar Thermal Program. Its major objectives are to accelerate the use of solar thermal systems through (a) direct technical assistance to users, (b) cooperative test, evaluation, and development efforts with private industry, and (c) educational outreach activities. This report outlines the major activities and accomplishments of the STDAC in Fiscal Year 1993. The report also contains a comprehensive list of persons who contacted the STDAC by telephone for information or technical consulting.

  1. Overview and Recent Accomplishments of Advanced Mirror Technology Development (AMTD) for Very Large Space Telescopes

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2013-01-01

    AMTD uses a science-driven systems engineering approach to define & execute a long-term strategy to mature technologies necessary to enable future large aperture space telescopes. Because we cannot predict the future, we are pursuing multiple technology paths including monolithic & segmented mirrors. Assembled outstanding team from academia, industry & government; experts in science & space telescope engineering. Derived engineering specifications from science measurement needs & implementation constraints. Maturing 6 critical technologies required to enable 4 to 8 meter UVOIR space telescope mirror assemblies for both general astrophysics & ultra-high contrast exoplanet imaging. AMTD achieving all its goals & accomplishing all its milestones.

  2. Nuclear Thermal Propulsion (NTP) Development Activities at the NASA Marshall Space Flight Center - 2006 Accomplishments

    NASA Technical Reports Server (NTRS)

    Ballard, Richard O.

    2007-01-01

    In 2005-06, the Prometheus program funded a number of tasks at the NASA-Marshall Space Flight Center (MSFC) to support development of a Nuclear Thermal Propulsion (NTP) system for future manned exploration missions. These tasks include the following: 1. NTP Design Develop Test & Evaluate (DDT&E) Planning 2. NTP Mission & Systems Analysis / Stage Concepts & Engine Requirements 3. NTP Engine System Trade Space Analysis and Studies 4. NTP Engine Ground Test Facility Assessment 5. Non-Nuclear Environmental Simulator (NTREES) 6. Non-Nuclear Materials Fabrication & Evaluation 7. Multi-Physics TCA Modeling. This presentation is a overview of these tasks and their accomplishments

  3. Overview and Accomplishments of Advanced Mirror Technology Development Phase 2 (AMTD-2) Project

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2015-01-01

    The Advance Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort, initiated in FY12, to mature by at least a half TRL step critical technologies required to enable 4 meter or larger UVOIR space telescope primary mirror assemblies for both general astrophysics and ultra-high contrast observations of exoplanets. AMTD Phase 1 completed all of its goals and accomplished all of its milestones. AMTD Phase 2 started in 2014. Key accomplishments include deriving primary mirror engineering specifications from science requirements; developing integrated modeling tools and using those tools to perform parametric design trades; and demonstrating new mirror technologies via sub-scale fabrication and test. AMTD-1 demonstrated the stacked core technique by making a 43-cm diameter 400 mm thick 'biscuit-cut' of a 4-m class mirror. AMTD-2 is demonstrating lateral scalability of the stacked core method by making a 1.5 meter 1/3rd scale model of a 4-m class mirror.

  4. Overview and accomplishments of advanced mirror technology development phase 2 (AMTD-2) project

    NASA Astrophysics Data System (ADS)

    Stahl, H. Philip

    2015-09-01

    The Advance Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort, initiated in FY12, to mature by at least a half TRL step critical technologies required to enable 4 meter or larger UVOIR space telescope primary mirror assemblies for both general astrophysics and ultra-high contrast observations of exoplanets. AMTD Phase 1 completed all of its goals and accomplished all of its milestones. AMTD Phase 2 started in 2014. Key accomplishments include deriving primary mirror engineering specifications from science requirements; developing integrated modeling tools and using those tools to perform parametric design trades; and demonstrating new mirror technologies via sub-scale fabrication and test. AMTD-1 demonstrated the stacked core technique by making a 43-cm diameter 400 mm thick `biscuit-cut' of a 4-m class mirror. AMTD-2 is demonstrating lateral scalability of the stacked core method by making a 1.5 meter 1/3rd scale model of a 4-m class mirror

  5. Design of a high activity and selectivity alcohol catalyst. Final status report and summary of accomplishments

    SciTech Connect

    Foley, H.C.; Mills, G.A.

    1994-07-15

    This final DOE report for grant award number DE-FG22-90PC 90291 presents the results of our efforts to better understand the Rh-Mo/{gamma}-Al{sub 2}O3 catalytic system for the hydrogenation of carbon monoxide and carbon dioxide to selectively form oxygenated products. The content of this report is divided into three major sections and a fourth, concluding section which addresses our major research accomplishments, as well as documents the most significant publications and presentations associated with this grant. The three main sections which make up the body of this report are presented in the in form of manuscripts which, in turn, summarize our progress in three areas of this project. The three body sections are organized as follows: Section I--Evidence for site isolation in Rh-Mo bimetallic catalysts derived from organometallic clusters; Section II--Surface Chemistry of Rh-Mo/{gamma}-Al{sub 2}O{sub 3}: An analysis of surface acidity; and Section III--Comparative study of Rh/Al{sub 2}O{sub 3} and Rh-Mo/Al{sub 2}O{sub 3} Catalysts. Section IV summarizes major accomplishments. The content of this final report is meant to generally highlight our progress in both characterizing the nature of the Rh-Mo/Al{sub 2}O{sub 3} system and probing its reactivity for insight on the oxygenate synergy present in this class of catalysts.

  6. The challenge

    NASA Astrophysics Data System (ADS)

    Freeman, Roger L.

    1988-01-01

    Radio systems in space are on the brink of achieving throughout data rates in the hundred of megabits. At present, radio systems operate below 60 GHz and are the traditional workhorses of satellite communications. Legal constraints and the laws of physics limit data rates on the systems. It is maintained that the challenge to provide high technology tools to develop viable high-data-rate space transmission systems can be met before the next century if three optical system and technology issues are overcome. In declining order of importance, the issues are: precise optical pointing, acquisition, and tracking; efficient laser diode optical sources producing sufficient output power; and advanced optical detector technology.

  7. International Research Results and Accomplishments From the International Space Station - A New Compilation

    NASA Technical Reports Server (NTRS)

    Ruttley, Tara; Robinson, Julie A.; Tate-Brown, Judy; Perkins, Nekisha; Cohen, Luchino; Marcil, Isabelle; Heppener, Marc; Hatton, Jason; Tasaki, Kazuyuki; Umemura, Sayaka; Karabadzhak, Georgy; Sorokin, Igor V.; Cotronei, Vittorio; Jean, Sabbagh

    2016-01-01

    In 2016, the International Space Station (ISS) partnership published the first-ever compilation of international ISS research publications resulting from research performed on the ISS through 2011 (Expeditions 0 through 30). International Space Station Research Accomplishments: An Analysis of Results. From 2000-2011 is a collection of over 1,200 journal publications that describe ISS research in the areas of biology and biotechnology; Earth and space science; educational activities and outreach; human research; physical sciences; technology development and demonstration; and, results from ISS operations. This paper will summarize the ISS results publications obtained through 2011 on behalf of the ISS Program Science Forum that is made up of senior science representatives across the international partnership. NASA's ISS Program Science office maintains an online experiment database (www.nasa.gov/iss- science) that tracks and communicates ISS research activities across the entire ISS partnership, and it is continuously updated by cooperation and linking with the results tracking activities of each partner. It captures ISS experiment summaries and results and includes citations to the journals, conference proceedings, and patents as they become available. This content is obtained through extensive and regular journal and patent database searches, and input provided by the ISS international partners ISS scientists themselves. The International Space Station Research Accomplishments: An Analysis of Results From 2000-2011 is a testament to the research that was underway even as the ISS laboratory was being built. It rejects the scientific knowledge gained from ISS research, and how it impact the fields of science in both space and traditional science disciplines on Earth. Now, during a time when utilization is at its busiest, and with extension of the ISS through at least 2024, the ISS partners work together to track the accomplishments and the new knowledge gained in a

  8. Continuing Challenges

    ERIC Educational Resources Information Center

    Fitzgerald, Tanya

    2012-01-01

    As the chapters in this book have identified, the academy and academics have experienced significant radical transformations across the past three decades. In many ways, academics have been eyewitnesses to these changes, and while there is much to mourn about what has been "lost", this is not the time for academic ambivalence towards the effects…

  9. Recent Accomplishments and Future Directions in US Fusion Safety & Environmental Program

    SciTech Connect

    David A. Petti; Brad J. Merrill; Phillip Sharpe; L. C. Cadwallader; L. El-Guebaly; S. Reyes

    2006-07-01

    The US fusion program has long recognized that the safety and environmental (S&E) potential of fusion can be attained by prudent materials selection, judicious design choices, and integration of safety requirements into the design of the facility. To achieve this goal, S&E research is focused on understanding the behavior of the largest sources of radioactive and hazardous materials in a fusion facility, understanding how energy sources in a fusion facility could mobilize those materials, developing integrated state of the art S&E computer codes and risk tools for safety assessment, and evaluating S&E issues associated with current fusion designs. In this paper, recent accomplishments are reviewed and future directions outlined.

  10. Advanced Mirror Technology Development (AMTD) Project: Overview and Year 4 Accomplishments

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2016-01-01

    The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature toward the next Technology Readiness Level (TRL) critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics and ultra-high-contrast observations of exoplanets. Key hardware accomplishments of 2015/16 are the successful low-temperature fusion of a 1.5-meter diameter ULE mirror that is a 1/3rd scale model of a 4-meter mirror and the initiation of polishing of a 1.2-meter Extreme-Lightweight Zerodur mirror. Critical to AMTD's success is an integrated team of scientists, systems engineers, and technologists; and a science-driven systems engineering approach.

  11. NASA/Army Rotorcraft Transmission Research, a Review of Recent Significant Accomplishments

    NASA Technical Reports Server (NTRS)

    Krantz, Timothy L.

    1994-01-01

    A joint helicopter transmission research program between NASA Lewis Research Center and the U.S. Army Research Lab has existed since 1970. Research goals are to reduce weight and noise while increasing life, reliability, and safety. These research goals are achieved by the NASA/Army Mechanical Systems Technology Branch through both in-house research and cooperative research projects with university and industry partners. Some recent significant technical accomplishments produced by this cooperative research are reviewed. The following research projects are reviewed: oil-off survivability of tapered roller bearings, design and evaluation of high contact ratio gearing, finite element analysis of spiral bevel gears, computer numerical control grinding of spiral bevel gears, gear dynamics code validation, computer program for life and reliability of helicopter transmissions, planetary gear train efficiency study, and the Advanced Rotorcraft Transmission (ART) program.

  12. A review of satellite time-transfer technology: Accomplishments and future applications

    NASA Technical Reports Server (NTRS)

    Cooper, R. S.; Chi, A. R.

    1978-01-01

    The research accomplishments by NASA in meeting the needs of the space program for precise time in satellite tracking are presented. As a major user of precise time signals for clock synchronization of NASA's worldwide satellite tracking networks, the agency provides much of the necessary impetus for the development of stable frequency sources and time synchronization technology. The precision time required for both satellite tracking and space science experiments has increased at a rate of about one order of magnitude per decade from 1 millisecond in the 1950's to 100 microseconds during the Apollo era in the 1960's to 10 microseconds in the 1970's. For the Tracking and Data Relay Satellite System, satellite timing requirements will be extended to 1 microsecond and below. These requirements are needed for spacecraft autonomy and data packeting.

  13. Summary of in situ vitrification modeling and analysis accomplishments for fiscal year 1991

    SciTech Connect

    Slater, C.E.

    1991-11-01

    The in situ vitrification (ISV) modeling activities encompass a variety of both modeling development efforts and analysis applications in support of the ISV project. The model development effort is directed toward modifying or developing a set of computer codes to simulate the ISV process. These codes are used to perform safety and environmental hazards analyses, assist in experimental test planning and design, assist in equipment design and development of operating procedures, and provide enhanced understanding of the ISV process. This report presents a summary description of the accomplishments in Fiscal Year 1991 for both the model development and analysis areas. Brief descriptions of the models that were developed and the more important conclusions from the analytical studies are presented.

  14. The Legacy of the Space Shuttle Program: Scientific and Engineering Accomplishments

    NASA Technical Reports Server (NTRS)

    Torrez, Jonathan

    2009-01-01

    The goal of this project was to assist in the creation of the appendix for the book being written about the Space Shuttle that is titled The Legacy of the Space Shuttle Program: Scientific and Engineering Accomplishments. The specific responsibility of the intern was the creation of the human health and performance (life sciences) and space biology sections of the appendix. This included examining and finalizing the list of flights with life sciences and space biology experiments flown aboard them, researching the experiments performed, synopsizing each experiment into two sentences, and placing the synopses into an appendix template. Overall, approximately 70 flights had their experiments synopsized and a good method for researching and construction of the template was established this summer.

  15. Advanced Industrial Materials (AIM) program. Compilation of project summaries and significant accomplishments FY 1996

    SciTech Connect

    1997-04-01

    In many ways, the Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven {open_quotes}Vision Industries{close_quotes} that use about 80% of industrial energy and generated about 90% of industrial wastes. These are: (1) Aluminum; (2) Chemical; (3) Forest Products; (4) Glass; (5) Metal Casting; (6) Refineries; and (7) Steel. This report is a compilation of project summaries and significant accomplishments on materials.

  16. International Space Station Research: Accomplishments and Pathways for Exploration and Fundamental Research

    NASA Technical Reports Server (NTRS)

    Robinson, Julie A.

    2007-01-01

    Beginning with the launch of the European Columbus module planned for December 2007, we approach a transition in the assembly of the International Space Station (ISS) that is of great importance for the sciences. During the following 18 months, we will operate the first experiments in Columbus physical science resource facilities and also launch and commission the Japanese Kibo module. In addition, two Multi-purpose Logistics Module (MPLM) flights will deliver the U.S. Combustion Integrated Rack (CIR) and Fluids Integrated Rack (FIR) along with their first science experiments. These facilities provide significant new capabilities for basic and applied physical science research in microgravity. New life support technologies will come online throughout 2008, and we will reach the milestone of a 6-person crew planned for April 2009. A larger crew enables significant more scientific use of all the facilities for the life of ISS. Planning for the use of the International Space Station as a national laboratory is also maturing as we near the completion of assembly, enabling access to ISS as a research platform for other government agencies and the private sector. The latest updates on National Laboratory implementation will also be provided in this presentation. At the same time as these significant increases in scientific capability, there have been significant ongoing accomplishments in NASA's early ISS research both exploration related and fundamental research. These accomplishments will be reviewed in context as harbingers of the capabilities of the International Space Station when assembly is complete. The Vision for Space Exploration serves to focus NASA's applied investigations in the physical sciences. However, the broader capability of the space station as a National Laboratory and as a nexus for international collaboration will also influence the study of gravity-dependent processes by researchers around the world.

  17. Student Accomplishments in the Rapid Response Radiotherapy Program: A 10-Year Review.

    PubMed

    McDonald, Rachel; Lechner, Breanne; Pulenzas, Natalie; Bedard, Gillian; Wong, Erin; Holden, Lori; Tsao, May; Barnes, Elizabeth; Szumacher, Ewa; Fenton, Gonenc; Chow, Edward; Popovic, Marko; Danjoux, Cyril

    2015-12-01

    In 1996, the Toronto Sunnybrook Regional Cancer Centre developed the Rapid Response Radiotherapy Program (RRRP). The objective of this clinic is to consult, simulate, plan, and treat patients with palliative radiotherapy on the same day. In 2004, the RRRP initiated a program to provide clinical and research experience to undergraduate students interested in health sciences. The purpose of this study is to review the 10-year (2004-2013) experience of the RRRP and to examine whether the goals of the student program have been met. Students who worked in the RRRP from 2004 to 2013 were contacted to complete a short survey regarding their overall experience with the program and their current endeavors. Student accomplishments were collected from an internal database as well as PubMed. Descriptive statistics were used to analyze results. A total of 54 students from ten postsecondary institutions have worked in the RRRP; 29 were from the University of Waterloo undergraduate co-op program. In total, 214 articles with first authorship from students were published, 93 (43%) of which can be found on PubMed. Other accomplishments include 40 book chapters, 58 invited presentations, and 99 awards cumulatively. Qualitative data regarding student perspectives of their experience in the RRRP were also analyzed. Over the past 10 years, the RRRP has achieved its goal of providing quality medical and research experience to students interested in the health sciences. Using the responses of past and present students, we hope to continue to shape our program and provide unique opportunities to future students. PMID:25370839

  18. 41 CFR 102-75.675 - What responsibilities does the grantee or recipient of the property have in accomplishing or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Real Property Disposal Property for Use As Public Park Or Recreation Areas § 102-75.675 What... recipient to bear the cost of any out-of-pocket expenses necessary to accomplish the transfer, such as...

  19. 41 CFR 102-75.675 - What responsibilities does the grantee or recipient of the property have in accomplishing or...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Real Property Disposal Property for Use As Public Park Or Recreation Areas § 102-75.675 What... recipient to bear the cost of any out-of-pocket expenses necessary to accomplish the transfer, such as...

  20. 41 CFR 102-75.675 - What responsibilities does the grantee or recipient of the property have in accomplishing or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Real Property Disposal Property for Use As Public Park Or Recreation Areas § 102-75.675 What... recipient to bear the cost of any out-of-pocket expenses necessary to accomplish the transfer, such as...

  1. 41 CFR 102-75.675 - What responsibilities does the grantee or recipient of the property have in accomplishing or...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Real Property Disposal Property for Use As Public Park Or Recreation Areas § 102-75.675 What... recipient to bear the cost of any out-of-pocket expenses necessary to accomplish the transfer, such as...

  2. 41 CFR 102-75.675 - What responsibilities does the grantee or recipient of the property have in accomplishing or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Real Property Disposal Property for Use As Public Park Or Recreation Areas § 102-75.675 What... recipient to bear the cost of any out-of-pocket expenses necessary to accomplish the transfer, such as...

  3. Comprehensive Test Ban Treaty research and development: plans and accomplishments ...from signature to entry into force

    SciTech Connect

    1998-06-01

    This brochure describes the high-priority R&D that is being pursued in the DOE Comprehensive Test Ban Treaty (CTBT) R&D Program and how it will support effective CTBT monitoring. Monitoring challenges, sensor systems, signal analysis, resolution of ambiguities, and the timeline for CTBT history and program milestones are covered.

  4. Indian Solar Cities Programme: An Overview of Major Activities and Accomplishments; Preprint

    SciTech Connect

    Kandt, A.

    2012-05-01

    This paper details the Indian Solar City Programme, provides an overview of one city's Master Plan and implementation progress, describes NREL's support of the Indian Solar City Programme, and outlines synergies and differences between the Indian and American programs including unique challenges and opportunities India is facing.

  5. Structural dynamics division research and technology accomplishments for fiscal year 1990 and plans for fiscal year 1991

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1991-01-01

    The research accomplishments of the Structural Dynamics Division for F.Y. 1991 are presented. The work is discussed in terms of highlights of accomplishments during the past year and plans for the current year as they relate to 5-year plans and the objectives of each technical area. Included is research on unsteady aerodynamics, helicopter rotors, computational fluid dynamics, oscillations of leading edge flaps of a delta wing, and aircraft wing loads.

  6. Daunting challenges.

    PubMed

    Wirth, T E

    1994-09-01

    Excerpts of a speech on behalf of the United States at the Third Preparatory Meeting of the International Conference on Population and Development on April 5, 1994 are presented. The Draft Program of Action defines an international agenda for the Cairo Conference and for sustained, priority action in the remainder of this century and on into the 21st. 1) Quality voluntary family planning and reproductive health services must be universally available early in the 21st century by broadening the contraceptive choice as well as expanding and improving reproductive health services without coercion. As President Clinton has said, abortion should be safe, legal, and rare. 2) Educating females is a priority because it raises the status of women as well as lowers infant and maternal mortality and poverty. 3) The extent must be assessed of the national unmet need for antenatal care, childbirth care, immunization, and the monitoring of growth and development. 4) Emphasizing to adolescents the responsibilities of sexuality will reinforce health, education, and economic objectives. 5) As women are empowered, so must men be empowered to be responsible in relation to fertility as well as sexual and reproductive health. 6) Responsible mutually respectful sexual behavior must be encouraged among both men and women and the importance of such behavior must be taught to both boys and girls. 7) Any discussion of responsibility must also include emphasis on the family, which is challenged globally as never before. 8) The Cairo conference provides the opportunity to discuss the current unprecedented migrations of human populations around the world; the link between environmental degradation and migration; and the potential effect of development programs on population movements. 9) North-South partnerships must be nurtured, recognizing the mutually reinforcing roles and responsibilities of all countries for sustainable development. PMID:12288264

  7. Accomplishment level and satisfaction with social participation of older adults: association with quality of life and best correlates

    PubMed Central

    Desrosiers, Johanne; Whiteneck, Gale

    2012-01-01

    Purpose This study aimed to (1) explore whether quality of life (QOL) is more associated with satisfaction with social participation (SP) than with level of accomplishment in SP and (2) examine respective correlates of accomplishment level and satisfaction with SP. Methods A cross-sectional design was used with a convenience sample of 155 older adults (mean age = 73.7; 60% women) having various levels of activity limitations. Accomplishment level and satisfaction with SP (dependent variables) were estimated with the social roles items of the assessment of life habits. Potential correlates were human functioning components. Results Correlations between QOL and accomplishment level and satisfaction with SP did not differ (P = 0.71). However, best correlates of accomplishment level and satisfaction with SP were different. Higher accomplishment level of SP was best explained by younger age, activity level perceived as stable, no recent stressing event, better well-being, higher activity level, and fewer obstacles in “Physical environment and accessibility” (R2 = 0.79). Greater satisfaction with SP was best explained by activity level perceived as stable, better self-perceived health, better well-being, higher activity level, and more facilitators in “Social support and attitudes” (R2 = 0.51). Conclusion With some exceptions, these best correlates may be positively modified and thus warrant special attention in rehabilitation interventions. PMID:20237957

  8. Professional conceptualisation and accomplishment of patient safety in mental healthcare: an ethnographic approach

    PubMed Central

    2011-01-01

    Background This study seeks to broaden current understandings of what patient safety means in mental healthcare and how it is accomplished. We propose a qualitative observational study of how safety is produced or not produced in the complex context of everyday professional mental health practice. Such an approach intentionally contrasts with much patient safety research which assumes that safety is achieved and improved through top-down policy directives. We seek instead to understand and articulate the connections and dynamic interactions between people, materials, and organisational, legal, moral, professional and historical safety imperatives as they come together at particular times and places to perform safe or unsafe practice. As such we advocate an understanding of patient safety 'from the ground up'. Methods/Design The proposed project employs a six-phase data collection framework in two mental health settings: an inpatient unit and a community team. The first four phases comprise multiple modes of focussed, unobtrusive observation of professionals at work, to enable us to trace the conceptualisation and enactment of safety as revealed in dialogue and narrative, use of artefacts and space, bodily activity and patterns of movement, and in the accomplishment of specific work tasks. An interview phase and a social network analysis phase will subsequently be conducted to offer comparative perspectives on the observational data. This multi-modal and holistic approach to studying patient safety will complement existing research, which is dominated by instrumentalist approaches to discovering factors contributing to error, or developing interventions to prevent or manage adverse events. Discussion This ethnographic research framework, informed by the principles of practice theories and in particular actor-network ideas, provides a tool to aid the understanding of patient safety in mental healthcare. The approach is novel in that it seeks to articulate an 'anatomy

  9. Adaptive challenges in medical practices.

    PubMed

    Daiker, Barbara L

    2013-01-01

    The purpose of this qualitative grounded theory study was to describe the theoretical structures of the strategies used by medical practices to navigate adaptive challenges. The process of responding to adaptive challenges in five medical practices was studied using a grounded theory approach, collecting data from interviews with the organizations' leaders and managers. The leadership of these medical practices had successfully navigated adaptive challenges within two years of the study. The analysis revealed a model that describes the key elements in finding solutions to adaptive challenges. The model was named the Adaptation Solution Dynamic, which explains the elements of Rational Tools, Relationship Commitment, and Achievement Drive. The findings from the results of this study provide a theoretical basis for studying how leaders support identifying solutions to adaptive challenges. PMID:23866647

  10. Satellite clock corrections estimation to accomplish real time ppp: experiments for brazilian real time network

    NASA Astrophysics Data System (ADS)

    Marques, Haroldo; Monico, João; Aquino, Marcio; Melo, Weyller

    2014-05-01

    The real time PPP method requires the availability of real time precise orbits and satellites clocks corrections. Currently, it is possible to apply the solutions of clocks and orbits available by BKG within the context of IGS Pilot project or by using the operational predicted IGU ephemeris. The accuracy of the satellite position available in the IGU is enough for several applications requiring good quality. However, the satellites clocks corrections do not provide enough accuracy (3 ns ~ 0.9 m) to accomplish real time PPP with the same level of accuracy. Therefore, for real time PPP application it is necessary to further research and develop appropriated methodologies for estimating the satellite clock corrections in real time with better accuracy. Currently, it is possible to apply the real time solutions of clocks and orbits available by Federal Agency for Cartography and Geodesy (BKG) within the context of IGS Pilot project. The BKG corrections are disseminated by a new proposed format of the RTCM 3.x and can be applied in the broadcasted orbits and clocks. Some investigations have been proposed for the estimation of the satellite clock corrections using GNSS code and phase observable at the double difference level between satellites and epochs (MERVAT, DOUSA, 2007). Another possibility consists of applying a Kalman Filter in the PPP network mode (HAUSCHILD, 2010) and it is also possible the integration of both methods, using network PPP and observables at double difference level in specific time intervals (ZHANG; LI; GUO, 2010). For this work the methodology adopted consists in the estimation of the satellite clock corrections based on the data adjustment in the PPP mode, but for a network of GNSS stations. The clock solution can be solved by using two types of observables: code smoothed by carrier phase or undifferenced code together with carrier phase. In the former, we estimate receiver clock error; satellite clock correction and troposphere, considering

  11. International Space Station Research for the Next Decade: International Coordination and Research Accomplishments

    NASA Technical Reports Server (NTRS)

    Thumm, Tracy L.; Robinson, Julie A.; Johnson-Green, Perry; Buckley, Nicole; Karabadzhak, George; Nakamura, Tai; Sorokin, Igor V.; Zell, Martin; Sabbagh, Jean

    2011-01-01

    During 2011, the International Space Station reached an important milestone in the completion of assembly and the shift to the focus on a full and continuous utilization mission in space. The ISS partnership itself has also met a milestone in the coordination and cooperation of utilization activities including research, technology development and education. We plan and track all ISS utilization activities jointly and have structures in place to cooperate on common goals by sharing ISS assets and resources, and extend the impacts and efficiency of utilization activities. The basic utilization areas on the ISS include research, technology development and testing, and education/outreach. Research can be categorized as applied research for future exploration, basic research taking advantage of the microgravity and open space environment, and Industrial R&D / commercial research focused at industrial product development and improvement. Technology development activities range from testing of new spacecraft systems and materials to the use of ISS as an analogue for future exploration missions to destinations beyond Earth orbit. This presentation, made jointly by all ISS international partners, will highlight the ways that international cooperation in all of these areas is achieved, and the overall accomplishments that have come as well as future perspectives from the cooperation. Recently, the partnership has made special efforts to increase the coordination and impact of ISS utilization that has humanitarian benefits. In this context the paper will highlight tentative ISS utilization developments in the areas of Earth remote sensing, medical technology transfer, and education/outreach.

  12. The ICES Working Group on Zooplankton Ecology: Accomplishments of the first 25 years

    NASA Astrophysics Data System (ADS)

    Wiebe, Peter H.; Harris, Roger; Gislason, Astthor; Margonski, Piotr; Skjoldal, Hein Rune; Benfield, Mark; Hay, Steve; O'Brien, Todd; Valdés, Luis

    2016-02-01

    The ICES Study Group on Zooplankton Ecology was created in 1991 to address issues of current and future concern within the field of zooplankton ecology. Within three years it became the ICES Working Group on Zooplankton Ecology (ICES WGZE) and this unique group in the world's oceanographic community has now been active for 25 years. This article reviews and synthesizes the products, and major accomplishments of the group. Achievements of the group, including the Zooplankton Methodology Manual, the Zooplankton Status Reports, and the International Zooplankton Symposia, have had an important impact on the wider field. Among the future issues that remain to be addressed by the group are the assessment of exploratory fisheries on zooplankton and micronekton species; further development of the zooplankton time-series; compilation and integration of allometric relationships for zooplankton species, and evaluation of new methodologies for the study of zooplankton distribution, abundance, physiology, and genetics. Marine science is an increasingly global undertaking and groups such as the ICES WGZE will continue to be essential to the advancement of understanding of zooplankton community structure and population dynamics in the world's oceans.

  13. AIRS Science Accomplishments Version 4.0/Plans for Version 5

    NASA Technical Reports Server (NTRS)

    Pagano, Thomas S.; Aumann, Hartmut; Elliott, Denis; Granger, Stephanie; Kahn, Brain; Eldering, Annmarie; Irion, Bill; Fetzer, Eric; Olsen, Ed; Lee, Sung-Yung; Okonek, Sharon; Friedman, Steve; Fishbein, Evan; Gaiser, Steve

    2006-01-01

    This talk is about accomplishments with AIRS data and what we have learned from almost three years of data what part of this is emerging in Version 4.0 what part we would like to see filtering into Version 5.0 and what part constitute limitations in the AIRS requirements, such as spectral and spatial resolution, which have to be deferred to the wish list for the next generation hyperspectral sounder. The AIRS calibration accuracy at the 1OOmK and stability at the 6 mK/year level are amazing. It establishes the unique capability of a cooled grating array spectrometer in Earth orbit for climate research. Data which are sufficiently clear to match the radiometric accuracy of the instrument, have a yield of less than 1%. This is OK for calibration. The 2616/cm window channel combined with the RTG.SST for tropical ocean allow excellent assessment radiometric calibration accuracy and stability. For absolute calibration verification 100mK is the limit due to cloud contamination. The 10 micron window channels can be used for stability assessment, but accuracy is limited at 300mK due to water continuum absorption uncertainties.

  14. Research accomplishments and future goals in particle physics. Final technical report

    SciTech Connect

    Not Available

    1994-06-01

    This proposal presents the research accomplishments and ongoing activities of Boston University researchers in high energy physics. Some changes have been made in the structure of the program from the previous arrangement of tasks. Task B, Accelerator Design Physics, is being submitted as a separate proposal for an independent grant; this will be consistent with the nature of the research and the source of funding. Boston University is active in seven principal areas: (1) Task A: Colliding Beams -- physics of e{sup +}e{sup {minus}} and {anti p}p collisions; (2) Task C: MACRO Experiment -- search for magnetic monopoles and study of cosmic rays; (3) Task D: Proton Decay -- search for nucleon instability and study of neutrino interactions; (4) Tasks E, J, and N: Particle Theory -- theoretical high energy particle physics, including two Outstanding Junior Investigator awards; (5) Task F: Muon G-2 -- measurement of the anomalous magnetic moment of the muon; (6) Task K: SSCintcal -- calorimetry for the GEM Experiment; (7) Task L: Muon Detectors for the GEM Experiment. The body of the proposal is devoted to detailed discussions of each of the tasks. The total budget request for the program appears in a summary chapter that includes a general budget discussion and individual budget requests and explanations for each of the tasks.

  15. Challenges in aerospace medicine education.

    PubMed

    Grenon, S Marlene; Saary, Joan

    2011-11-01

    Aerospace medicine training and research represents a dream for many and a challenge for most. In Canada, although some opportunities exist for the pursuit of education and research in the aerospace medicine field, they are limited despite the importance of this field for enabling safe human space exploration. In this commentary, we aim to identify some of the challenges facing individuals wishing to get involved in the field as well as the causal factors for these challenges. We also explore strategies to mitigate against these. PMID:22097645

  16. Data collection challenges in community settings: Insights from two field studies of patients with chronic disease

    PubMed Central

    Holden, Richard J.; McDougald Scott, Amanda M.; Hoonakker, Peter L.T.; Hundt, Ann S.; Carayon, Pascale

    2014-01-01

    Purpose Collecting information about health and disease directly from patients can be fruitfully accomplished using contextual approaches, ones that combine more and less structured methods in home and community settings. This paper's purpose is to describe and illustrate a framework of the challenges of contextual data collection. Methods A framework is presented based on prior work in community-based participatory research and organizational science, comprised of ten types of challenges across four broader categories. Illustrations of challenges and suggestions for addressing them are drawn from two mixed-method, contextual studies of patients with chronic disease in two regions of the US. Results The first major category of challenges was concerned with the researcher-participant partnership, for example, the initial lack of mutual trust and understanding between researchers, patients, and family members. The second category concerned patient characteristics such as cognitive limitations and a busy personal schedule that created barriers to successful data collection. The third concerned research logistics and procedures such as recruitment, travel distances, and compensation. The fourth concerned scientific quality and interpretation, including issues of validity, reliability, and combining data from multiple sources. The two illustrative studies faced both common and diverse research challenges and used many different strategies to address them. Conclusion Collecting less structured data from patients and others in the community is potentially very productive but requires the anticipation, avoidance, or negotiation of various challenges. Future work is necessary to better understand these challenges across different methods and settings, as well as to test and identify strategies to address them. PMID:25154464

  17. VAST 2010 Challenge: Arms Dealings and Pandemics

    SciTech Connect

    Grinstein, Georges; Konecni, Shawn; Plaisant, Catherine; Scholtz, Jean; Whiting, Mark A.

    2010-10-23

    The 5th VAST Challenge consisted of three mini-challenges that involved both intelligence analysis and bioinformatics. Teams could solve one, two or all three mini-challenges and assess the overall situation to enter the Grand Challenge. Mini-challenge one involved text reports about people and events giving information about arms dealers, situations in various countries and linkages between different countries. Mini-challenge two involved hospital admission and death records from various countries providing information about the spread of a world wide pandemic. Mini-challenge three involved genetic data to be used to identify the origin of the pandemic and the most dangerous viral mutations. The Grand Challenge was to determine how these various mini-challenges were connected. As always the goal was to analyze the data and provide novel interactive visualizations useful in the analytic process. We received 58 submissions in total and gave 15 awards.

  18. Cardiovascular Outcomes According to Systolic Blood Pressure in Patients With and Without Diabetes: An ACCOMPLISH Substudy.

    PubMed

    Weber, Michael A; Bloch, Michael; Bakris, George L; Weir, Matthew R; Zappe, Dion H; Dahlof, Bjorn; Velazquez, Eric J; Pitt, Bertram; Basile, Jan N; Jamerson, Kenneth; Hua, Tsushung A

    2016-04-01

    To evaluate the effects of achieved systolic blood pressure (SBP) during treatment on cardiovascular (CV) outcomes, the authors measured event rates of a composite primary endpoint (CV death or nonfatal myocardial infarction or stroke) at on-treatment SBPs of ≥140 mm Hg and the 10 mm Hg intervals of <140 mm Hg, <130 mm Hg, and <120 mm Hg in 6459 patients with diabetes (mean age, 67) and 4246 patients without diabetes (mean age, 69) from the Avoiding Cardiovascular Events in Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial. In the diabetic cohort, the primary endpoint was 49% lower (P<.001) at <140 mm Hg than at ≥140 mm Hg, and the separate components of this endpoint were also significantly reduced. Further SBP reductions did not improve outcomes, and at <120 mm Hg they were no longer different (except for stroke) from ≥140 mm Hg. In contrast, in the nondiabetic cohort, the primary endpoint event rate fell steadily (although not significantly) through the decreasing SBP categories until it was reduced by 45% (P=.0413) at <120 mm Hg. Total stroke rates for both the diabetic (-56%, P=.0120) and nondiabetic (-68%, P=.0067) cohorts were lowest at <120 mm Hg, and adverse renal events (serum creatinine increase ≥50%) were significantly lowest in the range of 130 mm Hg to 139 mm Hg for both cohorts. Diabetic patients (<140 mm Hg or <130 mm Hg) and nondiabetic patients (<120 mm Hg) may require different SBP targets for optimal CV protection, although stroke and renal considerations should also influence the selection of blood pressure targets. PMID:27060568

  19. Power wheelchair driving challenges in the community: a users’ perspective

    PubMed Central

    Torkia, Caryne; Reid, Denise; Korner-Bitensky, Nicol; Kairy, Dahlia; Rushton, Paula W.; Demers, Louise; Archambault, Philippe S.

    2015-01-01

    Purpose There is limited information on the difficulties individuals experience in manoeuvring their power wheelchairs during daily activities. The aim of this study was to describe the nature and context of power wheelchair driving challenges from the perspective of the user. Methods A qualitative design using semi-structured interviews with power wheelchair users. Qualitative content analysis was used to identify themes. Results Twelve experienced power wheelchair users were interviewed. Findings revealed that power wheelchair driving difficulties were related to the accomplishment of activities of daily living, and the influence of environmental context. Four key themes emerged: (1) difficulties accessing and using public buildings-facilities, (2) outdoor mobility, (3) problems in performing specific wheelchair mobility tasks/manoeuvres and (4) barriers and circumstances that are temporary, unforeseen or specific to a particular context. Conclusion This qualitative study furthers our understanding of the driving difficulties powered wheelchair (PW) users experience during daily activities. This knowledge will assist clinicians and researchers in two areas: in choosing assessment measures that are ecologically valid for power wheelchair users; and, in identifying and refining the content of training programs specific to the use of power wheelchairs. PMID:24640944

  20. School Rankings, Department Rankings, and Individual Accomplishments: What Factors Predict Obtaining Employment After the PhD?

    PubMed

    Stenstrom, Douglas M; Curtis, Mathew; Iyer, Ravi

    2013-03-01

    The outcome of a graduate student's hunt for employment is often attributed to the student's own accomplishments, the reputation of the department, and the reputation of the university. In 2007, a national survey of psychology graduate students was conducted to assess accomplishments and experiences in graduate school, part of which was an assessment of employment after completion of the doctorate (PhD). Five hundred and fifty-one respondents who had applied for employment reported whether they had obtained employment and in what capacity. Survey results were then integrated with the National Research Council's most recent official ranking system of academic departments. The strongest predictor of employment was department-level rankings even while controlling for individual accomplishments, such as publications, posters, and teaching experience. Equally accomplished applicants for an employment position were not equal, apparently, if they graduated from differently ranked departments. The results also show the degree to which school-level rankings, department-level rankings, and individual accomplishments uniquely predict the various types of employment, including jobs at PhD-granting institutions, master's-granting institutions, liberal arts colleges, 2-year schools, outside academia, or no employment at all. PMID:26172503

  1. Accomplishments in Field Period Assembly for NCSX* This is how we did it

    SciTech Connect

    Michael Viola, J. Edwards, T. Brown, L. Dudek, R. Ellis, P. Heitzenroeder, R. Strykowsky and Michael Cole

    2009-09-14

    The National Compact Stellarator Experiment (NCSX) was a collaborative effort between ORNL and PPPL. PPPL provided the assembly techniques with guidance from ORNL to meet design criteria. The individual vacuum vessel segments, modular coils, trim coils, and toroidal field coils components were delivered to the Field Period Assembly (FPA) crew who then would complete the component assemblies and then assemble the final three field period assemblies, each consisting of two sets of three modular coils assembled over a 120o vacuum vessel segment with the trim coils and toroidal field coils providing the outer layer. The requirements for positioning the modular coils were found to be most demanding. The assembly tolerances required for accurate positioning of the field coil windings in order to generate sufficiently accurate magnetic fields strained state of the art techniques in metrology and alignment and required constant monitoring of assembly steps with laser trackers, measurement arms, and photogrammetry. The FPA activities were being performed concurrently while engineering challenges were being resolved. For example, it was determined that high friction electrically isolated shims were needed between the modular coil interface joints and low distortion welding was required in the nose region of those joints. This took months of analysis and development yet the assembly was not significantly impacted because other assembly tasks could be performed in parallel with ongoing assembly tasks as well as tasks such as advance tooling setup preparation for the eventual welding tasks. The crew technicians developed unique, accurate time saving techniques and tooling which provided significant cost and schedule savings. Project management displayed extraordinary foresight and every opportunity to gain advanced knowledge and develop techniques was taken advantage of. Despite many risk concerns, the cost and schedule performance index was maintained nearly 1.0 during the

  2. Gang Identifiers and Terminology.

    ERIC Educational Resources Information Center

    Cantrell, Mary Lynn

    1992-01-01

    Provides lists of gang identifiers and terminology. Suggests that, to find out names and associated identifiers of local gangs, readers should talk to their local police. Included in listing are descriptions of gang-related symbols, physical signals, graffiti, slogans, right-left rules, colors, clothing, jewelry, hair styles, and fingernails. Also…

  3. Emissions from Open Burning: Evaluation Challenges at Different Scales

    NASA Astrophysics Data System (ADS)

    Wiedinmyer, C.; Emmons, L. K.; Raffuse, S. M.; Larkin, N. K.

    2011-12-01

    Open burning, whether wildland fires, prescribed burning, burning as part of agricultural practices, or even the burning of waste, emits significant amounts of trace gases and particulate matter to the atmosphere. These emissions can play an important role in local and regional air quality, global atmospheric chemistry, and climatic processes. Many valuable efforts have been put forth to estimate the emissions from open burning, ranging from event-specific and local scales, to regional and global scales. The results from these efforts are extremely valuable, since the inclusion of open burning events is essential to models that simulate air quality, chemistry, and climate. However, evaluation of these emission estimates remains a significant challenge and the uncertainty associated with the estimates is high. Burning emissions are episodic in nature, often occur on heterogeneous landscapes, and are variable throughout a day, a week, and even over months and seasons. The quantity and species of open burning emissions depend on the type of fuel burned, the condition of the fuel, and the way in which the fire burns. These characteristics add inherent difficulties for constraining open burning emissions. Additionally, the transport and transformation of open burning emissions in the atmosphere provides further challenges to their evaluation. This presentation will summarize some of the recent advances in open burning emission estimates, including emission estimates over various spatial and temporal scales that have been developed for various applications. Many efforts to evaluate the emissions, using measurements and models, have already been accomplished, providing information of success and challenges we still face. For example, recent studies using chemical transport models and observations from aircraft studies suggest that the carbon monoxide emissions predicted by the Fire INventory from NCAR in North America are too low. The results of the evaluations can be

  4. Facilitating Community: Key Strategies for Building Communities of Practice to Accomplish State Goals. New Eyes: Meeting Challenges through Communities of Practice

    ERIC Educational Resources Information Center

    Cashman, Joanne; Linehan, Patrice; Rosser, Mariola

    2007-01-01

    Communities of Practice offer state agency personnel a promising approach for engaging stakeholder groups in collaboratively solving complex and often persistent problems in special education. Communities of Practice can help state agency personnel drive strategy, solve problems, promote the spread of best practices, develop members' professional…

  5. Research: Accomplishments, Opportunities, Challenges. Proceedings of the Annual National Agricultural Education Research Conference (28th, New Orleans, LA, December 12, 2001).

    ERIC Educational Resources Information Center

    Kotrlik, Joe W., Ed.; Burnett, Michael F., Ed.

    This document contains 48 papers from a conference on agricultural education research. The following papers are among those included: "Analysis of the Relationships between Computer Experiences, Self-Efficacy, and Knowledge of Undergraduate Students Entering a Land-Grant College of Agriculture" (Donald M. Johnson, Melissa L. Lester, James A.…

  6. Promoting Quality Teaching: New Approaches to Compensation and Career Pathways. Perspectives from Accomplished California Teachers

    ERIC Educational Resources Information Center

    National Board Resource Center at Stanford University, 2012

    2012-01-01

    This report identifies what are thought to be smart ways to redesign career paths and compensation for California teachers. It is known which changes are most likely to improve both teaching quality and student achievement, because these changes address what really matters in schools and what motivates teachers. These are not the traditional and…

  7. The Simultaneous Production of Educational Achievement and Popularity: How Do Some Pupils Accomplish It?

    ERIC Educational Resources Information Center

    Francis, Becky; Skelton, Christine; Read, Barbara

    2010-01-01

    In spite of research showing that pupils--particularly boys--tend to experience tension between high academic achievement and popularity with peers at school, some pupils continue to maintain simultaneous production of both. This article focuses on a sample of 12-13 year-old pupils, identified as high achieving and popular, to examine classroom…

  8. Accomplishing the Goals of Affirmative Action--with or without Affirmative Action

    ERIC Educational Resources Information Center

    Sternberg, Robert J.

    2005-01-01

    Might it be possible to achieve some or all of the goals of affirmative action through an approach based on an entirely different definition of the problem? This article says "yes." Its logic rests not upon an approach that creates informal quotas for identified groups, but instead on one aimed at discovering merit in people who are members of…

  9. Cyber Security Indications and Warning System (SV): CRADA 1573.94 Project Accomplishments Summary

    SciTech Connect

    Hu, Tan Chang; Robinson, David G.

    2011-09-08

    As the national focus on cyber security increases, there is an evolving need for a capability to provide for high-speed sensing of events, correlation of events, and decision-making based on the adverse events seen across multiple independent large-scale network environments. The purpose of this Shared Vision project, Cyber Security Indications and Warning System, was to combine both Sandia's and LMC's expertise to discover new solutions to the challenge of protecting our nation's infrastructure assets. The objectives and scope of the proposal was limited to algorithm and High Performance Computing (HPC) model assessment in the unclassified environment within funding and schedule constraints. The interest is the identification, scalability assessment, and applicability of current utilized cyber security algorithms as applied in an HPC environment.

  10. MODIS Validation, Data Merger and Other Activities Accomplished by the SIMBIOS Project: 2002-2003

    NASA Technical Reports Server (NTRS)

    Fargion, Giulietta S.; McClain, Charles R.

    2003-01-01

    The purpose of this technical report is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, satellite data processing, and data product validation. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report focuses on the SIMBIOS Project s efforts in support of the Moderate-Resolution Imaging Spectroradiometer (MODIS) on the Earth Observing System (EOS) Terra platform (similar evaluations of MODIS/Aqua are underway). This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project.

  11. President's Challenge. Spotlight: Physical Development.

    ERIC Educational Resources Information Center

    Montessori Life, 2000

    2000-01-01

    Describes the President's Challenge, a program of fitness testing for 6- to 17-year-olds from the President's Council on Physical Fitness and Sports. Identifies requirements for the Presidential Physical Fitness Award for exercises and running, by age level and sex. Includes information on the validity of the award standards. (KB)

  12. Vocational Psychology and New Challenges

    ERIC Educational Resources Information Center

    Metz, A. J.; Guichard, Jean

    2009-01-01

    A discussion group composed of vocational psychologists, guidance professionals, and career development specialists from around the world identified and discussed new challenges in understanding work and providing relevant career services. Four major themes emerged: What revisions are necessary in the profession's theory and practice to address…

  13. Identifying the Multiple Intelligences of Your Students

    ERIC Educational Resources Information Center

    McClellan, Joyce A.; Conti, Gary J.

    2008-01-01

    One way of addressing individual differences among adult learners is to identify the Multiple Intelligences of the learner. Multiple Intelligences refers to the concept developed by Howard Gardner that challenges the traditional view of intelligence and explains the presence of nine different Multiple Intelligences. The purpose of this study was…

  14. Accomplishments of the Advanced Reusable Technologies (ART) RBCC Project at NASA/Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Nelson, Karl W.; McArthur, J. Craig (Technical Monitor)

    2001-01-01

    and parametrics were performed at NASA / Glenn Research Center (GRC) and NASA / Langley Research Center (LaRC) for both the Aerojet and Rocketdyne concepts. LaRC conducted an Air-Breathing Launch Vehicle (ABLV) study for several vehicle concepts with RBCC propulsion systems. LaRC is also performing a CFD analysis of the ramjet mode for both flowpaths based on GASL test conditions. A study was performed in 1999 to investigate the feasibility of performing an RBCC flight test on the NASA / Dryden Flight Research Center (DFRC) SR-71 aircraft. Academia involvement in the ART project includes parametric RBCC flowpath testing by Pennsylvania State University (PSU). In addition to thrust and wall static pressure measurements, PSU is also using laser diagnostics to analyze the flowfield in the test rig. MSFC is performing CFD analysis of the PSU rig at select test conditions for model baseline and validation. Also, Georgia Institute of Technology (GT) conducted a vision vehicle study using the Aerojet RBCC concept. Overall, the ART project has been very successful in advancing RBCC technology. Along the way, several major milestones were achieved and "firsts" accomplished. For example, under the ART project, the first dynamic trajectory simulation testing was performed and the Rocketdyne engine A5 logged over one hour of accumulated test time. The next logical step is to develop and demonstrate a flight-weight RBCC engine system.

  15. The challenge to balloon science

    NASA Astrophysics Data System (ADS)

    Jones, W. Vernon

    A thorough review of the NASA balloon program in 1995 confirmed both the inherent importance of balloon science investigations and their value for developing technology for future space missions. A follow-on study in 1996 looked into restructuring the entire suborbital program, in order to find more efficient and effective ways of doing business. These studies were mandated by the adverse impact of NASA's declining budgets and work force constraints on all aspects of space research. The challenge is to accomplish more with less. The balloon program began stepping up to this challenge several years ago with the advent of 10 - 20 day long-duration flights in Antarctica. We must now push ahead with enhanced flight capabilities and with new science instrument technologies, as we forge alliances with other modes of low-cost access to space. Specifically, the development of sealed superpressure balloons could extend flight duration by another order of magnitude, to about 100 days, making ballooning even more competitive with space missions.

  16. The First Use of the Learning Accomplishment Profile (LAP) in Prekindergarten Head Start 1976-1977. Report Number 77137.

    ERIC Educational Resources Information Center

    Silbermann, David J.

    Prekindergarten Head Start teachers were trained to administer the Learning Accomplishment Profile (LAP), an objective check list of development in seven areas: gross motor, fine motor manipulation and writing, social, self help, cognitive, and language skills. Data were collected from separate groups of 3, 4, and 5-year old children to ascertain…

  17. TERRA FIRMA. Threshold of Educational Reform Restructuring Agriculture for Inner City Related Motivation and Accomplishments. Final Report.

    ERIC Educational Resources Information Center

    Fulmer, John L.

    The report describes the first year (1974-75) activities and accomplishments of a project to provide a cooperative-based vocational agriculture program for secondary students in Anniston, Alabama. The overall objectives were to provide instruction in livestock production and horticulture, leadership training, participatory experience on a real…

  18. Accomplishments and Compromises in Prediction Research for World Records and Best Performances in Track and Field and Swimming

    ERIC Educational Resources Information Center

    Liu, Yuanlong; Paul, Stanley; Fu, Frank H.

    2012-01-01

    The conductors of this study reviewed prediction research and studied the accomplishments and compromises in predicting world records and best performances in track and field and swimming. The results of the study showed that prediction research only promises to describe the historical trends in track and field and swimming performances, to study…

  19. "He Talks to You, Not at You": Attending to Learners' Perspectives to Enhance Understanding of Accomplished Teaching

    ERIC Educational Resources Information Center

    Kriewaldt, Jeana

    2009-01-01

    The voices of students can make a significant contribution to understanding what constitutes accomplished teaching (Flutter, 2007). Young people give cogent and significant views about their learning, providing important insights for improving teaching (Rudduck, McIntyre, & ESRC Teaching and Learning Programme., 2007). Using a qualitative…

  20. SB08 212 Legislative Update Report: Colorado's Achievement Plan for Kids (CAP4K) 2010 Goals and Accomplishments

    ERIC Educational Resources Information Center

    Colorado Department of Education, 2011

    2011-01-01

    This paper serves as the Colorado Department of Education's (CDE's) third annual update on the progress and plan for the implementation of the Colorado Achievement Plan for Kids (CAP4K). Enclosed within this report is a narrative that documents accomplishments to date with respect to key deliverables, as well as supporting appendices, including…

  1. Advancing computational toxicology in a regulatory setting: A selected review of the accomplishments of Gilman D. Veith (1944-2013)

    EPA Science Inventory

    Gilman Veith joined the US Environmental Protection Agency (EPA), and its Office of Research and Development, in 1972. Spanning 30 years of public service with EPA through 2003, Gil’s accomplishments in leading multidisciplinary research teams to successfully address a broad spe...

  2. Investing in the Improvement of Mathematics and Science Education in Rural Appalachia: Ten Years of ARSI and Its Accomplishments

    ERIC Educational Resources Information Center

    Inverness Research Associates, 2006

    2006-01-01

    This report provides the reader with a summary of the rationale, design strategies, and major accomplishments of the Appalachian Rural Systemic Initiative (ARSI). Drawing upon both the data collected directly in Appalachia by Inverness Research Associates, as well as knowledge gained by working with many other rural initiatives, this summary…

  3. The challenges of CT colonography reimbursement.

    PubMed

    Dachman, Abraham H; Yee, Judy

    2013-12-01

    CT colonography has been shown to be an effective method to screen for colorectal cancer. However, at present, full endorsement and reimbursement for screening CT colonography, particularly by the US Preventive Services Task Force and CMS, respectively, are absent, so this screening option is infrequently used, and optical colonoscopy remains the de facto standard screening option. The authors summarize the past accomplishments that led to the current state of reimbursement and outline the remaining challenges and road to full acceptance and reimbursement of screening CT colonography nationally. PMID:24295944

  4. Metal alloy identifier

    DOEpatents

    Riley, William D.; Brown, Jr., Robert D.

    1987-01-01

    To identify the composition of a metal alloy, sparks generated from the alloy are optically observed and spectrographically analyzed. The spectrographic data, in the form of a full-spectrum plot of intensity versus wavelength, provide the "signature" of the metal alloy. This signature can be compared with similar plots for alloys of known composition to establish the unknown composition by a positive match with a known alloy. An alternative method is to form intensity ratios for pairs of predetermined wavelengths within the observed spectrum and to then compare the values of such ratios with similar values for known alloy compositions, thereby to positively identify the unknown alloy composition.

  5. Translating the Tuberculosis Research Agenda: Much Accomplished, but Much More to Be Done.

    PubMed

    Schito, Marco; Maeurer, Markus; Kim, Peter; Hanna, Debra; Zumla, Alimuddin

    2015-10-15

    Despite the availability of effective diagnostics and curative treatment regimens for tuberculosis, millions of people die each year of this disease. The steady global increase in the number of tuberculosis cases caused by multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis are of major concern, especially in light of the thin tuberculosis drug pipeline. New tuberculosis drugs are undergoing clinical evaluation, and renewed hope comes from fresh approaches to improve treatment outcomes using a range of adjunct host-directed cellular and repurposed drug therapies. Current efforts in developing second-generation and new rapid point-of-care diagnostic assays take advantage of recent genetic and molecular advances. Slow progress in the development of prophylactic and therapeutic vaccines requires increased funding for basic as well as translational research. Although major challenges remain, these can be overcome by cementing our resolve, raising advocacy, bolstering global funder investments, and leveraging more effective collaborations through equitable public-private partnerships. PMID:26409286

  6. Identifying Technical Vocabulary

    ERIC Educational Resources Information Center

    Chung, Teresa Mihwa; Nation, Paul

    2004-01-01

    This study compared four different approaches to identifying technical words in an anatomy text. The first approach used a four step rating scale, and was used as the comparison for evaluating the other three approaches. It had a high degree of reliability. The least successful approach was that using clues provided by the writer such as labels in…

  7. Identifying and Managing Risk.

    ERIC Educational Resources Information Center

    Abraham, Janice M.

    1999-01-01

    The role of the college or university chief financial officer in institutional risk management is (1) to identify risk (physical, casualty, fiscal, business, reputational, workplace safety, legal liability, employment practices, general liability), (2) to develop a campus plan to reduce and control risk, (3) to transfer risk, and (4) to track and…

  8. CTF Challenge: Result Summary

    PubMed Central

    Marabini, Roberto; Carragher, Bridget; Chen, Shaoxia; Chen, James; Cheng, Anchi; Downing, Kenneth H.; Frank, Joachim; Grassucci, Robert A.; Heymann, J. Bernard; Jiang, Wen; Jonic, Slavica; Liao, Hstau Y.; Ludtke, Steven J.; Patwari, Shail; Piotrowski, Angela L.; Quintana, Adrian; Sorzano, Carlos O.S.; Stahlberg, Henning; Vargas, Javier; Voss, Neil R.; Chiu, Wah; Carazo, Jose M.

    2015-01-01

    Image formation in bright field electron microscopy can be described with the help of the contrast transfer function (CTF). In this work the authors describe the “CTF Estimation Challenge”, called by the Madrid Instruct Image Processing Center (I2PC) in collaboration with the National Center for Macromolecular Imaging (NCMI) at Houston. Correcting for the effects of the CTF requires accurate knowledge of the CTF parameters, but these have often been difficult to determine. In this challenge, researchers have had the opportunity to test their ability in estimating some of the key parameters of the electron microscope CTF on a large micrograph data set produced by well-known laboratories on a wide set of experimental conditions. This work presents the first analysis of the results of the CTF Estimation Challenge, including an assessment of the performance of the different software packages under different conditions, so as to identify those areas of research where further developments would be desirable in order to achieve high-resolution structural information. PMID:25913484

  9. Challenges to academic psychiatry.

    PubMed

    Pardes, H; Pincus, H A

    1983-09-01

    Economic constraints, effects of retrenchments in federal health policy, and increased competition for resources are challenging all sectors of academic medicine. Departments of psychiatry are at particular risk during this era for reasons including the lack of a sound research and research training base in many psychiatry departments; the small number of students entering the field and implications therein for the availability of residency slots in psychiatry; and patterns of allocating resources within academic medical centers which, combined with biases in reimbursement policy toward cognitively based specialties, threaten the economic strength of psychiatric departments. A conceptual model based on marketing principles is proposed to aid in identifying and capitalizing on the unique strengths of the field. PMID:6412571

  10. Reusable Solid Rocket Motor - Accomplishments, Lessons, and a Culture of Success

    NASA Technical Reports Server (NTRS)

    Moore, Dennis R.; Phelps, Willie J.

    2011-01-01

    The Reusable Solid Rocket Motor represents the largest solid rocket motor ever flown and the only human rated solid motor. Each Reusable Solid Rocket Motor (RSRM) provides approximately 3-million lb of thrust to lift the integrated Space Shuttle vehicle from the launch pad. The motors burn out approximately 2 minutes later, separate from the vehicle and are recovered and refurbished. The size of the motor and the need for high reliability were challenges. Thrust shaping, via shaping of the propellant grain, was needed to limit structural loads during ascent. The motor design evolved through several block upgrades to increase performance and to increase safety and reliability. A major redesign occurred after STS-51L with the Redesigned Solid Rocket Motor. Significant improvements in the joint sealing systems were added. Design improvements continued throughout the Program via block changes with a number of innovations including development of low temperature o-ring materials and incorporation of a unique carbon fiber rope thermal barrier material. Recovery of the motors and post flight inspection improved understanding of hardware performance, and led to key design improvements. Because of the multidecade program duration material obsolescence was addressed, and requalification of materials and vendors was sometimes needed. Thermal protection systems and ablatives were used to protect the motor cases and nozzle structures. Significant understanding of design and manufacturing features of the ablatives was developed during the program resulting in optimization of design features and processing parameters. The project advanced technology in eliminating ozone-depleting materials in manufacturing processes and the development of an asbestos-free case insulation. Manufacturing processes for the large motor components were unique and safety in the manufacturing environment was a special concern. Transportation and handling approaches were also needed for the large

  11. An Examination of Rebuild America Partnership Accomplishments and the Factors Influencing Them

    SciTech Connect

    Schweitzer, M.

    2003-10-16

    The Rebuild America program was established in 1994 to accelerate the adoption of energy efficiency measures and practices in existing public facilities, commercial buildings, and multifamily housing units. More recently, the program has expanded to include new construction as well. The program encourages the formation of partnerships involving state and local governments, private businesses, and other organizations to help identify and solve problems related to energy use in buildings. Rebuild America does not directly fund actual building improvements. Instead, it provides the Rebuild Partners with the technical tools and assistance they need to plan and implement building projects and stimulates other entities to make substantial investments in energy efficiency. At the request of the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy, staff at Oak Ridge National Laboratory studied the Rebuild America program for the purpose of identifying key factors associated with successful operations. Substantial amounts of data were collected directly from Rebuild America partnerships concerning the results achieved by each of their individual projects, both committed and completed. In addition, data were collected from secondary sources on a limited number of factors describing partnership setting and characteristics. By combining these two data sets, we were able to perform statistical analyses testing the potential relationship between each partnership characteristic and each of four key results measures. The influences on successful partnership performance also were determined in another way, which allowed a broader examination of potentially important factors. Telephone interviews were conducted with representatives from 61 high-performing Rebuild America partnerships throughout the United States. The respondents were asked to identify the most important factors influencing good performance and the types of Rebuild America products, services

  12. Grand Challenges of Enterprise Integration

    SciTech Connect

    Brosey, W.D; Neal, R.E.; Marks, D.

    2001-04-01

    Enterprise Integration connects and combines people, processes, systems, and technologies to ensure that the right people and the right processes have the right information and the right resources at the right time. A consensus roadmap for Technologies for Enterprise Integration was created as part of an industry/government/academia partnership in the Integrated Manufacturing Technology Initiative (IMTI). Two of the grand challenges identified by the roadmapping effort will be addressed here--Customer Responsive Enterprises and Totally Connected Enterprises. Each of these challenges is briefly discussed as to the current state of industry and the future vision as developed in the roadmap.

  13. Main research accomplishments during the past three-year period, [December 1, 1985--November 30, 1988

    SciTech Connect

    Linn, S.M.

    1991-12-31

    We have purified HeLa DNA polymerase {var_epsilon} (pol {var_epsilon}), showed it to be a unique and newly-described DNA polymerase, and modified our permeabilized cell assay accordingly. We partially purified correcting factors for Xeroderma Pigmentosum (XP) XP-A and E. We showed that a DNA binding protein is absent from two XP-E cell lines, but normal in others. We purified and characterized UV indoor III, a correcting factor for XP-D. We finished our characterization of mammalian UV endos I and II. We identified, purified, and characterized AP endonuclease and DNA glycosylase activities from mitochondria -- hence, mitochondria do have the means to carry out base excision repair of oxidative damage.

  14. Behavioral genetics '97: ASHG statement. Recent developments in human behavioral genetics: past accomplishments and future directions.

    PubMed Central

    Sherman, S L; DeFries, J C; Gottesman, I I; Loehlin, J C; Meyer, J M; Pelias, M Z; Rice, J; Waldman, I

    1997-01-01

    The field of behavioral genetics has enormous potential to uncover both genetic and environmental influences on normal and deviant behavior. Behavioral-genetic methods are based on a solid foundation of theories and methods that successfully have delineated components of complex traits in plants and animals. New resources are now available to dissect the genetic component of these complex traits. As specific genes are identified, we can begin to explore how these interact with environmental factors in development. How we interpret such findings, how we ask new questions, how we celebrate the knowledge, and how we use or misuse this knowledge are all important considerations. These issues are pervasive in all areas of human research, and they are especially salient in human behavioral genetics. PMID:9199545

  15. Objectives, accomplishments, and future plans of IGCP project 143, remote sensing and mineral exploration

    USGS Publications Warehouse

    Carter, W.D.; Rowan, L.C.

    1981-01-01

    The International Geological Correlation Programme (IGCP) is a worldwide cooperative research programme that began in 1974 under the auspices of the International Union of Geological Sciences. Because of the global availability of Earth resources data collected by satellites and the great interest among geologists in taking advantage of these new sources of information, a project was begun in 1976 to improve the rate of technology transfer in the field of remote-sensing exploration for energy and mineral resources. Conducting joint workshops in cooperation with COSPAR has been an important part of this project. It is to be hoped the project will improve our capability to explore, identify, and develop new resources to meet the burgeoning demands of society. ?? 1981.

  16. Community genetics: what have we accomplished and where should we be going?

    PubMed Central

    Hersch-Green, Erika I.; Turley, Nash E.; Johnson, Marc T. J.

    2011-01-01

    Research in community genetics seeks to understand how the dynamic interplay between ecology and evolution shapes simple and complex communities and ecosystems. A community genetics perspective, however, may not be necessary or informative for all studies and systems. To better understand when and how intraspecific genetic variation and microevolution are important in community and ecosystem ecology, we suggest future research should focus on three areas: (i) determining the relative importance of intraspecific genetic variation compared with other ecological factors in mediating community and ecosystem properties; (ii) understanding the importance of microevolution in shaping ecological dynamics in multi-trophic communities; and (iii) deciphering the phenotypic and associated genetic mechanisms that drive community and ecosystem processes. Here, we identify key areas of research that will increase our understanding of the ecology and evolution of complex communities but that are currently missing in community genetics. We then suggest experiments designed to meet these current gaps. PMID:21444318

  17. Accomplishing the Visions for Professional Development of Teachers Advocated in the National Science Education Standards

    NASA Astrophysics Data System (ADS)

    Yager, Robert E.

    2005-05-01

    The National Science Education Standards include suggested visions for changing staff development programs for preparing new teachers and working with inservice teachers. Analyzing the visions for the most successful programs precedes the identification of programs that best match the NSES visions. The National Science Teachers Association is publishing a new monograph that identifies 16 model programs that approach the visions while also providing actual evidence of the successes experienced. This manuscript is an attempt to provide a setting and a rationale for the national search and for informing science teacher educators in the features of the best programs nominated after a 4-year search. Instead of only describing science teacher education programs for new and inservice teachers, actual evidence establishing their validity is offered. Perhaps the examples will be more useful if the framework and procedures used in their selections are shared with Association for Science Teacher Education members.

  18. Advanced Industrial Materials (AIM) Program: Compilation of project summaries and significant accomplishments, FY 1997

    SciTech Connect

    1998-05-01

    The mission of the Advanced Industrial Materials (AIM) Program is to support development and commercialization of new or improved materials to improve energy efficiency, productivity, product quality, and reduced waste in the major process industries. A fundamentally new way of working with industries--the Industries of the Future (IOF) strategy--concentrates on the major process industries that consume about 90% of the energy and generate about 90% of the waste in the industrial sector. These are the aluminum, chemical, forest products, glass, metalcasting, and steel industries. OIT has encouraged and assisted these industries in developing visions of what they will be like 20 or 30 years into the future, defining the drivers, technology needs, and barriers to realization of their visions. These visions provide a framework for development of technology roadmaps and implementation plans. The AIM Program supports IOF by conducting research and development on materials to solve problems identified in the roadmaps. This is done by National Laboratory/industry/university teams with the facilities and expertise needed to develop new and improved materials. Each project in the AIM Program has active industrial participation and support. Assessments of materials needs and opportunities in the process industries are an on-going effort within the program. These assessments are being used for program planning and priority setting, followed by support of work to satisfy those needs. All the industries have identified materials as critical, particularly for high-temperature strength, corrosion resistance, and wear resistance. Also important from the energy efficiency viewpoint are membranes, catalytic membranes, and reactors for separations, both for processing and waste reduction. AIM focuses, therefore, on high-temperature materials, corrosion resistant materials, wear resistant materials, strong polymers, coatings, and membrane materials for industrial applications.

  19. Deep Vadose Zone Characterization at the Hanford Site: Accomplishments from the Last Ten Years

    SciTech Connect

    Brown, C.F.; Serne, R.J.

    2008-07-01

    The overall goal of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities at Hanford. To meet this goal, CH2M HILL Hanford Group, Inc. tasked scientists from Pacific Northwest National Laboratory (PNNL) to perform detailed analyses on vadose zone sediments collected within/adjacent to the twelve single-shell tank farms contained within Hanford's Central Plateau region. This work has been performed under the Resource Conservation and Recovery Act (RCRA) Corrective Action Program and is associated with the Hanford Federal Facility Agreement and Consent Order. While there are many facets to the laboratory studies employed by PNNL, the four primary objectives of this work are to: identify the type and quantity of contamination present, understand the physical processes that affect the transport of contaminants in the vadose zone sediments, when practical, identify the source(s) of the contamination found in the sediment samples, and when practical, determine if a link can be made between the vadose zone contamination observed and any known groundwater contaminants in the vicinity. Since its inception in 1997, PNNL's Vadose Zone Characterization Project has evolved to better meet these four key objectives. The single-largest adaptation of the Vadose Zone Characterization Project over its ten years of operation was the advent of a tiered sample analysis approach. Use of a tiered approach allows resources to be focused on those samples/tests that provide the largest amount of scientific information to best meet the four key project objectives within the budget available. Another significant, but more recent, adaptation has been the implementation of a rapid turnaround characterization process in which sediment samples are analyzed in near real-time to aid drilling activities within the tank farms. This paper highlights details of the characterization activities performed as well

  20. Deep Vadose Zone Characterization at the Hanford Site: Accomplishments from the Last Ten Years

    SciTech Connect

    Brown, Christopher F.; Serne, R. Jeffrey

    2008-02-28

    The overall goal of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities at Hanford. To meet this goal, CH2M HILL Hanford Group, Inc. tasked scientists from Pacific Northwest National Laboratory (PNNL) to perform detailed analyses on vadose zone sediments collected within/adjacent to the twelve single-shell tank farms contained within Hanford’s Central Plateau region. This work has been performed under the Resource Conservation and Recovery Act (RCRA) Corrective Action Program and is associated with the Hanford Federal Facility Agreement and Consent Order. While there are many facets to the laboratory studies employed by PNNL, the four primary objectives of this work are to: identify the type and quantity of contamination present, understand the physical processes that affect the transport of contaminants in the vadose zone sediments, when practical, identify the source(s) of the contamination found in the sediment samples, and when practical, determine if a link can be made between the vadose zone contamination observed and any known groundwater contaminants in the vicinity. Since its inception in 1997, PNNL’s Vadose Zone Characterization Project has evolved to better meet these four key objectives. The single-largest adaptation of the Vadose Zone Characterization Project over its ten years of operation was the advent of a tiered sample analysis approach. Use of a tiered approach allows resources to be focused on those samples/tests that provide the largest amount of scientific information to best meet the four key project objectives within the budget available. Another significant, but more recent, adaptation has been the implementation of a rapid turnaround characterization process in which sediment samples are analyzed in near real-time to aid drilling activities within the tank farms. This paper highlights details of the characterization activities performed as

  1. INFORMATION: Special Report on "Management Challenges at the Department of Energy"

    SciTech Connect

    2009-12-01

    Responsible for some of the Nation's most important and technically advanced missions, the Department of Energy faces an array of challenges that are more wide-ranging and complex than at any time in its history. While its origins can be largely traced to the Manhattan Project, the Department has evolved into a multi-faceted agency that encompasses a broad range of scientific, environmental, and national security activities. Since its creation under the Department of Energy Organization Act in 1977, the Department has shifted its emphasis and priorities over time as the energy and security needs of the Nation have changed. The Department has recently refocused these efforts, adding particular emphasis on the science and renewable energy components of its portfolio. In this regard, the Department has taken a lead role in the implementation and execution of the energy technology initiatives related to the American Recovery and Reinvestment Act of 2009 (Recovery Act). As a means of accomplishing these initiatives, the Department received a substantial increase in its annual appropriation, rising from nearly $25 billion in 2008 to approximately $34 billion in 2009 as a result of additional funding in the Department's loan program and numerous science, energy, and national security initiatives. In addition, the Department was provided more than $36 billion in Recovery Act funding to be used over a two to three year period. Further, the Department, through existing authorities and those expanded by the Recovery Act, has been authorized to provide more than $100 billion in loan guarantees for innovative, clean energy technologies. To accomplish its vital missions, the Department employs approximately 115,000 Federal and contractor personnel and manages assets valued at more than $189 billion, including the 17 national laboratories at the heart of its science program. On an annual basis, the Office of Inspector General is required to identify what it considers to be the

  2. Developing a Watershed Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2010-01-01

    This article presents a watershed challenge that gives students an opportunity to investigate the challenge of using a watershed area as a site for development, examining the many aspects of this multifaceted problem. This design challenge could work well in a team-based format, with students taking on specific aspects of the challenges and…

  3. Challenges and Changes Faced by Rural Superintendents

    ERIC Educational Resources Information Center

    Lamkin, Marcia L.

    2006-01-01

    This research study was designed to build grounded theory about the challenges faced by rural superintendents. Participating rural superintendents identified five areas that presented a challenge but that also applied to superintendents in other settings: school law, finance, personnel, government mandates, and district or board policies. Further,…

  4. A Longitudinal Examination of Serious Adolescent Offenders’ Perceptions of Chances for Success and Engagement in Behaviors Accomplishing Goals

    PubMed Central

    Iselin, Anne-Marie R.; Mulvey, Edward P.; Loughran, Thomas A.; Chung, He Len; Schubert, Carol A.

    2011-01-01

    We examined antisocial adolescents’ perceptions of the importance of and their ability to accomplish positive life outcomes (e.g., employment) and avoid negative ones (e.g., arrests) during their transition from adolescence to young adulthood. Participants were 1,354 adolescents from the Pathways to Desistance project, a multisite longitudinal study of seriously antisocial adolescents. Participants’ perceptions of the importance and likelihood of accomplishing positive adult goals at one age uniquely predicted how often they engaged in behaviors that were consistent with these goals the following year. Our findings suggest that among serious adolescent offenders aspirations to achieve positive goals are related to engaging in behaviors that bring adolescents’ current selves more in line with their aspired-to future selves. We discuss the implications of these findings for prevention and intervention efforts. PMID:21881855

  5. Structural dynamics division research and technology accomplishments for F.Y. 1991 and plans for F.Y. 1992

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1992-01-01

    The work under each technical area is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest. The structural dynamics division consist of the following branches: configuration aeroelasticity; unsteady aerodynamics; aeroservoelasticity; landing and impact dynamics; and spacecraft dynamics.

  6. Identification and characterization of a second major peanut allergen, Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge.

    PubMed

    Burks, A W; Williams, L W; Connaughton, C; Cockrell, G; O'Brien, T J; Helm, R M

    1992-12-01

    Peanuts are frequently a cause of food hypersensitivity reactions in children. Serum from nine patients with atopic dermatitis and a positive double-blind, placebo-controlled, food challenge to peanut were used in the process of identification and purification of the peanut allergens. Identification of a second major peanut allergen was accomplished with use of various biochemical and molecular techniques. Anion exchange chromatography of the crude peanut extract produced several fractions that bound IgE from the serum of the patient pool with positive challenges. By measuring antipeanut specific IgE and by IgE-specific immunoblotting we have identified an allergic component that has two closely migrating bands with a mean molecular weight of 17 kd. Two-dimensional gel electrophoresis of this fraction revealed it to have a mean isoelectric point of 5.2. According to allergen nomenclature of the IUIS Subcommittee for Allergen Nomenclature this allergen is designated, Ara h II (Arachis hypogaea). PMID:1460200

  7. University of Arkansas Pine Bluff. Final report/project accomplishments summary, CRADA Number 95-KCPP-004

    SciTech Connect

    Lane, M.A.

    1997-03-01

    The purpose of this project was to help develop and transfer technologies to improve the production of the catfish segment of American aquaculture. This project was organized to leverage two DOE programs, DOE Historical Black Colleges and Universities (HBCU) funds and Defense Program Technology Transfer Initiative. The emphasis was to be directed toward utilizing engineering and manufacturing capabilities to develop solutions to the industry problems through the technology transfer program. The project scope included the following: (1) review the technical needs of the aquaculture industry in the state of Arkansas; (2) match the technical capabilities of FM and T with the needs of the industry; (3) form joint projects between FM and T and UAPB. Four areas of immediate interest were identified: (1) dissolved oxygen sensor system improvements; (2) alternatives to seining; (3) fish inventory and sizing; (4) improved off-flavor detection. In the first project a technical literature search was conducted by UAPB with consultation from FM and T. It was determined that commercial dissolved oxygen sensor equipment is available that could be used to upgrade the monitoring for aquaculture use. Initial results of the Alternatives to Seining project concluded that either acoustic or electric field technology can be used to herd the fish as the traditional seine does. The balance of the project was canceled when project funding at UAPB was canceled.

  8. Accomplishments of the Abrupt Wing Stall (AWS) Program and Future Research Requirements

    NASA Technical Reports Server (NTRS)

    Hall, Robert M.; Woodson, Shawn H.; Chambers, Joseph R.

    2003-01-01

    The Abrupt Wing Stall (AWS) Program has addressed the problem of uncommanded lateral motions, such as wing drop and wing rock, at transonic speeds. The genesis of this Program was the experience of the F/A-1 8E/F Program in the late 1990's, when wing drop was discovered in the heart of the maneuver envelope for the pre-production aircraft. While the F/A-1 8E/F problem was subsequently corrected by a leading-edge flap scheduling change and the addition of a porous door to the wing fold fairing, the AWS Program was initiated as a national response to the lack of technology readiness available at the time of the F/A-18E/F Development Program. The AWS Program objectives were to define causal factors for the F/A-18E/F experience, to gain insights into the flow physics associated with wing drop, and to develop methods and analytical tools so that future programs could identify this type of problem before going to flight test. The paper reviews, for the major goals of the AWS Program, the status of the technology before the

  9. ACCOMPLISHMENTS OF THE AMERICAN-POLISH PROGRAM FOR ELIMINATION OF LOW EMISSIONS IN KRAKOW

    SciTech Connect

    BUTCHER,T.A.; PIERCE,B.

    1998-11-05

    In 1991, US and Polish officials signed a Memorandum of Understanding formally initiating and directing the Cracow Clean Fossil Fuels and Energy Efficiency Program. Developing a program approach for the most effective use of the available funds required considerable effort on the part of all project participants. The team recognized early that the cost of solving the low emissions problem even in only one city far exceeded the amount of available US funds. Economic conditions in Poland limited availability of local capital funds for environmental projects. Imposing environmental costs on struggling companies or city residents under difficult conditions of the early 1990's required careful consideration of the economic and political impacts. For all of these reasons the program sought to identify technologies for achieving air quality goals which, through improved efficiency and/or reduced fuel cost, could be so attractive economically as to lead to self-sustaining activities beyond the end of the formal project. The effort under this program has been focused into 5 main areas of interest as follows: (1) Energy Conservation and Extension of Central Station District Heating; (2) Replacement of Coal- and Coke-Fired Boilers with Natural Gas-Fired Boilers; (3) Replacement of Coal-Fired Home Stoves with Electric Heating Appliances; (4) Reduction of Emissions from Stoker-Fired Boiler Houses; and (5) Reduction of Emissions from Coal-Fired Home Heating Stoves.

  10. Software IV and V Research Priorities and Applied Program Accomplishments Within NASA

    NASA Technical Reports Server (NTRS)

    Blazy, Louis J.

    2000-01-01

    The mission of this research is to be world-class creators and facilitators of innovative, intelligent, high performance, reliable information technologies that enable NASA missions to (1) increase software safety and quality through error avoidance, early detection and resolution of errors, by utilizing and applying empirically based software engineering best practices; (2) ensure customer software risks are identified and/or that requirements are met and/or exceeded; (3) research, develop, apply, verify, and publish software technologies for competitive advantage and the advancement of science; and (4) facilitate the transfer of science and engineering data, methods, and practices to NASA, educational institutions, state agencies, and commercial organizations. The goals are to become a national Center Of Excellence (COE) in software and system independent verification and validation, and to become an international leading force in the field of software engineering for improving the safety, quality, reliability, and cost performance of software systems. This project addresses the following problems: Ensure safety of NASA missions, ensure requirements are met, minimize programmatic and technological risks of software development and operations, improve software quality, reduce costs and time to delivery, and improve the science of software engineering

  11. The NASA/industry design analysis methods for vibrations (DAMVIBS) program: Accomplishments and contributions

    NASA Technical Reports Server (NTRS)

    Kvaternik, Raymond G.

    1991-01-01

    A NASA Langley-sponsored rotorcraft structural dynamics program, known as Design Analysis Methods for VIBrationS (DAMVIBS), has been under development since 1984. The objective of this program was to establish the technology base needed by the industry to develop an advanced finite-element-based dynamics design analysis capability for vibrations. Under the program, teams from the four major helicopter manufacturers have formed finite-element models, conducted ground vibration tests, made test/analysis comparisons of both metal and composite airframes, performed 'difficult components' studies on airframes to identify components which need more complete finite-element representation for improved correlation, and evaluated industry codes for computing coupled rotor-airframe vibrations. Studies aimed at establishing the role that structural optimization can play in airframe vibrations design work have also been initiated. Five government/industry meetings were held in connection with these activities during the course of the program. Because the DAMVIBS Program is coming to an end, the fifth meeting included a brief assessment of the program and its benefits to the industry.

  12. On identified predictive control

    NASA Technical Reports Server (NTRS)

    Bialasiewicz, Jan T.

    1993-01-01

    Self-tuning control algorithms are potential successors to manually tuned PID controllers traditionally used in process control applications. A very attractive design method for self-tuning controllers, which has been developed over recent years, is the long-range predictive control (LRPC). The success of LRPC is due to its effectiveness with plants of unknown order and dead-time which may be simultaneously nonminimum phase and unstable or have multiple lightly damped poles (as in the case of flexible structures or flexible robot arms). LRPC is a receding horizon strategy and can be, in general terms, summarized as follows. Using assumed long-range (or multi-step) cost function the optimal control law is found in terms of unknown parameters of the predictor model of the process, current input-output sequence, and future reference signal sequence. The common approach is to assume that the input-output process model is known or separately identified and then to find the parameters of the predictor model. Once these are known, the optimal control law determines control signal at the current time t which is applied at the process input and the whole procedure is repeated at the next time instant. Most of the recent research in this field is apparently centered around the LRPC formulation developed by Clarke et al., known as generalized predictive control (GPC). GPC uses ARIMAX/CARIMA model of the process in its input-output formulation. In this paper, the GPC formulation is used but the process predictor model is derived from the state space formulation of the ARIMAX model and is directly identified over the receding horizon, i.e., using current input-output sequence. The underlying technique in the design of identified predictive control (IPC) algorithm is the identification algorithm of observer/Kalman filter Markov parameters developed by Juang et al. at NASA Langley Research Center and successfully applied to identification of flexible structures.

  13. [Stellar Occultation Studies of Small Bodies in the Outer Solar System: Accomplishments, Status, and Plans

    NASA Technical Reports Server (NTRS)

    Elliott, James

    2005-01-01

    Bodies residing in the outer solar system exhibit unique physical processes, and some of the lessons learned from them can be applied to understanding what occurred in the outer solar system during its formation and early evolution. Pluto, the largest known Kuiper Belt object (KBO), and its near twin Triton--an ex-KBO that has been captured by Neptune--have nitrogen atmospheres that are in vapor-pressure equilibrium with surface ice. These atmospheres are most sensitively probed from Earth by the technique of Stellar occultations, which can provide the temperature and pressure profiles of these atmospheres at a spatial resolution of a few kilometers. Recent results from occultations show that the surface pressure of Triton's atmosphere has been increasing and that the shape of the atmosphere deviates from its expected spherical figure. With the occultation technique we can also learn the sizes of smaller bodies that have formed in the outer solar system: Charon, the Centaurs, and KBOs. Our proposed program involves identifying occultation candidates, predicting occultations, observing occultations, analysis of the data, and synthesis of the occultation results with other data. The main goals for our proposed work are to (i) further observe occultations by Triton with the objectives of understanding its pressure changes, distortion, and enigmatic thermal structure (ii) determine whether the abrupt drop in Pluto's stellar occultation light curve is caused by a sharp thermal gradient near its surface or by atmospheric haze, (iii) further observations to characterize the potential collapse of Pluto's atmosphere as it recedes from the sun (information that should be of interest to the Pluto-Kuiper Express), ( iv ) determine Charon's radius more accurately than can be done with the mutual events to derive a better estimate of Charon's density, and ( v ) directly determine the size (and albedo) of Centaurs with the goal of more accurately estimating the sizes of KBOS.

  14. The Greater Challenge.

    ERIC Educational Resources Information Center

    Imig, David G.

    1986-01-01

    Describes and praises ways in which the Holmes Group report, committed to redesigning the education of teachers, goes beyond prior movements to reform teacher education. Urges the active cooperation of universities, granting agencies, politicians, faculties, teachers, and others in supporting and accomplishing the required changes. (IW)

  15. List identifies threatened ecosystems

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-09-01

    The International Union for Conservation of Nature (IUCN) announced on 9 September that it will develop a new Red List of Ecosystems that will identify which ecosystems are vulnerable or endangered. The list, which is modeled on the group's Red List of Threatened Species™, could help to guide conservation activities and influence policy processes such as the Convention on Biological Diversity, according to the group. “We will assess the status of marine, terrestrial, freshwater, and subterranean ecosystems at local, regional, and global levels,” stated Jon Paul Rodriguez, leader of IUCN's Ecosystems Red List Thematic Group. “The assessment can then form the basis for concerted implementation action so that we can manage them sustainably if their risk of collapse is low or restore them if they are threatened and then monitor their recovery.”

  16. Identifying potential academic leaders

    PubMed Central

    White, David; Krueger, Paul; Meaney, Christopher; Antao, Viola; Kim, Florence; Kwong, Jeffrey C.

    2016-01-01

    Objective To identify variables associated with willingness to undertake leadership roles among academic family medicine faculty. Design Web-based survey. Bivariate and multivariable analyses (logistic regression) were used to identify variables associated with willingness to undertake leadership roles. Setting Department of Family and Community Medicine at the University of Toronto in Ontario. Participants A total of 687 faculty members. Main outcome measures Variables related to respondents’ willingness to take on various academic leadership roles. Results Of all 1029 faculty members invited to participate in the survey, 687 (66.8%) members responded. Of the respondents, 596 (86.8%) indicated their level of willingness to take on various academic leadership roles. Multivariable analysis revealed that the predictors associated with willingness to take on leadership roles were as follows: pursuit of professional development opportunities (odds ratio [OR] 3.79, 95% CI 2.29 to 6.27); currently holding at least 1 leadership role (OR 5.37, 95% CI 3.38 to 8.53); a history of leadership training (OR 1.86, 95% CI 1.25 to 2.78); the perception that mentorship is important for one’s current role (OR 2.25, 95% CI 1.40 to 3.60); and younger age (OR 0.97, 95% CI 0.95 to 0.99). Conclusion Willingness to undertake new or additional leadership roles was associated with 2 variables related to leadership experiences, 2 variables related to perceptions of mentorship and professional development, and 1 demographic variable (younger age). Interventions that support opportunities in these areas might expand the pool and strengthen the academic leadership potential of faculty members. PMID:27331226

  17. Climate challenges, vulnerabilities, and food security

    PubMed Central

    Nelson, Margaret C.; Ingram, Scott E.; Dugmore, Andrew J.; Streeter, Richard; Peeples, Matthew A.; McGovern, Thomas H.; Hegmon, Michelle; Arneborg, Jette; Brewington, Seth; Spielmann, Katherine A.; Simpson, Ian A.; Strawhacker, Colleen; Comeau, Laura E. L.; Torvinen, Andrea; Madsen, Christian K.; Hambrecht, George; Smiarowski, Konrad

    2016-01-01

    This paper identifies rare climate challenges in the long-term history of seven areas, three in the subpolar North Atlantic Islands and four in the arid-to-semiarid deserts of the US Southwest. For each case, the vulnerability to food shortage before the climate challenge is quantified based on eight variables encompassing both environmental and social domains. These data are used to evaluate the relationship between the “weight” of vulnerability before a climate challenge and the nature of social change and food security following a challenge. The outcome of this work is directly applicable to debates about disaster management policy. PMID:26712017

  18. Climate challenges, vulnerabilities, and food security.

    PubMed

    Nelson, Margaret C; Ingram, Scott E; Dugmore, Andrew J; Streeter, Richard; Peeples, Matthew A; McGovern, Thomas H; Hegmon, Michelle; Arneborg, Jette; Kintigh, Keith W; Brewington, Seth; Spielmann, Katherine A; Simpson, Ian A; Strawhacker, Colleen; Comeau, Laura E L; Torvinen, Andrea; Madsen, Christian K; Hambrecht, George; Smiarowski, Konrad

    2016-01-12

    This paper identifies rare climate challenges in the long-term history of seven areas, three in the subpolar North Atlantic Islands and four in the arid-to-semiarid deserts of the US Southwest. For each case, the vulnerability to food shortage before the climate challenge is quantified based on eight variables encompassing both environmental and social domains. These data are used to evaluate the relationship between the "weight" of vulnerability before a climate challenge and the nature of social change and food security following a challenge. The outcome of this work is directly applicable to debates about disaster management policy. PMID:26712017

  19. 78 FR 49296 - Centennial Challenges 2014 Sample Return Robot Challenge

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... SPACE ADMINISTRATION Centennial Challenges 2014 Sample Return Robot Challenge AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Centennial Challenges 2014 Sample Return Robot... Robot Challenge is scheduled and teams that wish to compete may register. Centennial Challenges is...

  20. Minority Innovation Challenges Institute

    NASA Video Gallery

    Do you want to learn more about how to compete in NASA’s technical challenges for both prestige and significant cash prizes? NASA’s Minority Innovation Challenges Institute trains and mentors mino...

  1. Green Flight Challenge

    NASA Video Gallery

    The CAFE Green Flight Challenge sponsored by Google will be held at the CAFE Foundation Flight Test Center at Charles M. Schulz Sonoma County Airport in Santa Rosa, Calif. The Green Flight Challeng...

  2. Identifying Young, Nearby Stars

    NASA Technical Reports Server (NTRS)

    Webb, Rich; Song, Inseok; Zuckerman, Ben; Bessell, Mike

    2001-01-01

    Young stars have certain characteristics, e.g., high atmospheric abundance of lithium and chromospheric activity, fast rotation, distinctive space motion and strong X-ray flux compared to that of older main sequence stars. We have selected a list of candidate young (<100Myr) and nearby (<60pc) stars based on their space motion and/or strong X-ray flux. To determine space motion of a star, one needs to know its coordinates (RA, DEC), proper motion, distance, and radial velocity. The Hipparcos and Tycho catalogues provide all this information except radial velocities. We anticipate eventually searching approx. 1000 nearby stars for signs of extreme youth. Future studies of the young stars so identified will help clarify the formation of planetary systems for times between 10 and 100 million years. Certainly, the final output of this study will be a very useful resource, especially for adaptive optics and space based searches for Jupiter-mass planets and dusty proto-planetary disks. We have begun spectroscopic observations in January, 2001 with the 2.3 m telescope at Siding Spring Observatory (SSO) in New South Wales, Australia. These spectra will be used to determine radial velocities and other youth indicators such as Li 6708A absorption strength and Hydrogen Balmer line intensity. Additional observations of southern hemisphere stars from SSO are scheduled in April and northern hemisphere observations will take place in May and July at the Lick Observatory of the University of California. AT SSO, to date, we have observed about 100 stars with a high resolution spectrometer (echelle) and about 50 stars with a medium spectral resolution spectrometer (the "DBS"). About 20% of these stars turn out to be young stars. Among these, two especially noteworthy stars appear to be the closest T-Tauri stars ever identified. Interestingly, these stars share the same space motions as that of a very famous star with a dusty circumstellar disk--beta Pictoris. This new finding better

  3. Catalytic nanomotors: challenges and opportunities

    NASA Astrophysics Data System (ADS)

    Gibbs, John; Zhao, Yiping

    2011-06-01

    The fabrication of integrated nanomachinary systems can enable break-through applications in nanoelectronics, photonics, bioengineering, and drug delivery or disease treatment. Naturally occurring nanomotors are biological motor proteins powered by catalytic reactions, which convert the chemical energy from the environment into mechanical energy directly. It has been demonstrated recently that using a simple catalytic reaction and an asymmetric bimetallic nanorod, one can produce catalytic nanomotors that mimic the autonomous motions of bionanomotors. Yet the construction of artificial nanomachines remains a major contemporary challenge due to the lack of a flexible fabrication technique that can design the desired dynamic components. We use a design technique called dynamic shadowing growth that allows for the fabrication of a wide range of various geometries and the asymmetric placement of the catalyst is easily accomplished as well which is necessary for directed propulsion. Programming nanomotor behavior is possible through geometrically-focused design and by incorporating different materials into the nanomotor structure is a simple process as well. A propulsion mechanism based upon bubble ejection from the catalyst surface is introduced to explain the driving force, and the comparison of this driving mechanism with the self-electrophoresis mechanism is also studied. We have also successfully incorporated multiple parts to form complex nanomotor assemblies which exhibit motions not observed from individual parts by using magnetic interactions.

  4. The Challenges of Credible Thermal Protection System Reliability Quantification

    NASA Technical Reports Server (NTRS)

    Green, Lawrence L.

    2013-01-01

    The paper discusses several of the challenges associated with developing a credible reliability estimate for a human-rated crew capsule thermal protection system. The process of developing such a credible estimate is subject to the quantification, modeling and propagation of numerous uncertainties within a probabilistic analysis. The development of specific investment recommendations, to improve the reliability prediction, among various potential testing and programmatic options is then accomplished through Bayesian analysis.

  5. Exploring the challenges faced by polytechnic students

    NASA Astrophysics Data System (ADS)

    Matore, Mohd Effendi @ Ewan Mohd; Khairani, Ahmad Zamri

    2015-02-01

    This study aims to identify other challenges besides those already faced by students, in seven polytechnics in Malaysia as a continuation to the previous research that had identified 52 main challenges faced by students using the Rasch Model. The explorative study focuses on the challenges that are not included in the Mooney Problem Checklist (MPCL). A total of 121 polytechnic students submitted 183 written responses through the open questions provided. Two hundred fifty two students had responded from a students' perspective on the dichotomous questions regarding their view on the challenges faced. The data was analysed qualitatively using the NVivo 8.0. The findings showed that students from Politeknik Seberang Perai (PSP) gave the highest response, which was 56 (30.6%) and Politeknik Metro Kuala Lumpur (PMKL) had the lowest response of 2 (1.09%). Five dominant challenges were identified, which were the English language (32, 17.5%), learning (14, 7.7%), vehicles (13, 7.1%), information technology and communication (ICT) (13, 7.1%), and peers (11, 6.0%). This article, however, focus on three apparent challenges, namely, English language, vehicles, as well as computer and ICT, as the challenges of learning and peers had been analysed in the previous MPCL. The challenge of English language that had been raised was regarding the weakness in commanding the aspects of speech and fluency. The computer and ICT challenge covered the weakness in mastering ICT and computers, as well as computer breakdowns and low-performance computers. The challenge of vehicles emphasized the unavailability of vehicles to attend lectures and go elsewhere, lack of transportation service in the polytechnic and not having a valid driving license. These challenges are very relevant and need to be discussed in an effort to prepare polytechnics in facing the transformational process of polytechnics.

  6. The Backpack Design Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2010-01-01

    Something as simple as carrying books to school can be an interesting design challenge for students. It's an old problem that gets reinvented from time to time. In this article, the author discusses a backpack design challenge in which teachers work with students to design another way to carry books to school. The challenge started by trying to…

  7. Tunnel Vision Prismatic Field Expansion: Challenges and Requirements

    PubMed Central

    Apfelbaum, Henry; Peli, Eli

    2015-01-01

    Purpose No prismatic solution for peripheral field loss (PFL) has gained widespread acceptance. Field extended by prisms has a corresponding optical scotoma at the prism apices. True expansion can be achieved when each eye is given a different view (through visual confusion). We analyze the effects of apical scotomas and binocular visual confusion in different designs to identify constraints on any solution that is likely to meet acceptance. Methods Calculated perimetry diagrams were compared to perimetry with PFL patients wearing InWave channel prisms and Trifield spectacles. Percept diagrams illustrate the binocular visual confusion. Results Channel prisms provide no benefit at primary gaze. Inconsequential extension was provided by InWave prisms, although accessible with moderate gaze shifts. Higher-power prisms provide greater extension, with greater paracentral scotoma loss, but require uncomfortable gaze shifts. Head turns, not eye scans, are needed to see regions lost to the apical scotomas. Trifield prisms provide field expansion at all gaze positions, but acceptance was limited by disturbing effects of central binocular visual confusion. Conclusions Field expansion when at primary gaze (where most time is spent) is needed while still providing unobstructed central vision. Paracentral multiplexing prisms we are developing that superimpose shifted and see-through views may accomplish that. Translational Relevance Use of the analyses and diagramming techniques presented here will be of value when considering prismatic aids for PFL, and could have prevented many unsuccessful designs and the improbable reports we cited from the literature. New designs must likely address the challenges identified here. PMID:26740910

  8. IAI Information and Priority District Programs: A Case Study Involving the Instructional Accomplishments of Hispanic Students in Racially Isolated Schools. Technical Report 76.

    ERIC Educational Resources Information Center

    Bachelor, Barry

    Instructional Accomplishment Information (IAI) systems provide schools and school districts with information for reviewing and planning their instructional programs at the class, school, and district levels. This study demonstrated the use of IAI information to illuminate further the instructional accomplishments of schools priority program to…

  9. 41 CFR 102-75.740 - Does the State agency have any responsibilities in helping to accomplish the transfer of the...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Does the State agency have any responsibilities in helping to accomplish the transfer of the property? 102-75.740 Section 102... helping to accomplish the transfer of the property? Yes, the State agency is required to bear the costs...

  10. 41 CFR 102-75.740 - Does the State agency have any responsibilities in helping to accomplish the transfer of the...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Does the State agency have any responsibilities in helping to accomplish the transfer of the property? 102-75.740 Section 102... helping to accomplish the transfer of the property? Yes, the State agency is required to bear the costs...

  11. 41 CFR 102-75.740 - Does the State agency have any responsibilities in helping to accomplish the transfer of the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Does the State agency have any responsibilities in helping to accomplish the transfer of the property? 102-75.740 Section 102... helping to accomplish the transfer of the property? Yes, the State agency is required to bear the costs...

  12. 41 CFR 102-75.740 - Does the State agency have any responsibilities in helping to accomplish the transfer of the...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Does the State agency have any responsibilities in helping to accomplish the transfer of the property? 102-75.740 Section 102... helping to accomplish the transfer of the property? Yes, the State agency is required to bear the costs...

  13. 41 CFR 102-75.740 - Does the State agency have any responsibilities in helping to accomplish the transfer of the...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Does the State agency have any responsibilities in helping to accomplish the transfer of the property? 102-75.740 Section 102... helping to accomplish the transfer of the property? Yes, the State agency is required to bear the costs...

  14. Challenges in Piaget's legacy.

    PubMed

    Bibace, Roger

    2013-03-01

    The publication of After Piaget (Martí and Rodríguez 2012) hopefully triggers a new effort to understand the richness of the efforts of that major psychologist of the 20th century. Piaget was consistently concerned with part/whole relationships throughout his life. He addressed this issue philosophically, epistemologically, and psychologically. Conceptually Piaget struggled with the issue of continuity/discontinuity in development and changed his mind about how to reconcile the discontinuities of stages with his concept of development. I also attribute his variability to the implications of his important work on perception, and to his willingness to get involved in widespread concrete applications of his approach to education including the education of children with special needs; his center for genetic epistemology, and his interest in psychoanalysis. Benefiting from all the authors of After Piaget, I want to point out that Piaget has identified many major issues that will continue to constitute challenges to psychology in this century. These include specifying terms such as 'development;' methodological issues such as sampling both quantitatively in one culture and across cultures; comprehensive inclusion of the psychological processes covered by introductory textbooks in psychology; and conceptual issues such as the relationships among all these parts within a whole. I make a distinction between an 'issue' and a 'problem'--problems have solutions; while issues refer to controversies in science generally as well as in psychology that have persisted for centuries. PMID:22733313

  15. Accomplishing Districtwide Reform

    ERIC Educational Resources Information Center

    Sharratt, Lyn; Fullan, Michael

    2006-01-01

    This is a mystery story. It is about a district that apparently did the right things but seemed not to get commensurate results across all classrooms and schools. In this article, we look closely at the details and discover an important lesson about districtwide reform. The district is York Region District School Board, which is a large…

  16. Spacelab Accomplishments Forum 4

    NASA Technical Reports Server (NTRS)

    Emond, J. (Editor); Bennet, N. (Compiler); McCauley, D. (Compiler); Murphy, K. (Compiler); Baugher, Charles R. (Technical Monitor)

    1999-01-01

    The Spacelab Module, exposed platforms, and supporting instrumentation were designed and developed by the European Space Agency to house advanced experiments inside the Space Shuttle cargo bay. The Spacelab program has hosted a cross-disciplinary research agenda over a 17-year flight history. Several variations of Spacelab were used to host payloads for almost every space research discipline that NASA pursues-life sciences, microgravity research, space sciences, and earth observation studies. After seventeen years of flight, Spacelab modules, pallets, or variations thereof flew on the Shuttle 36 times for a total of 375 flight days.

  17. Meteorological satellite accomplishments

    NASA Technical Reports Server (NTRS)

    Allison, L. J.; Arking, A.; Bandeen, W. R.; Shenk, W. E.; Wexler, R.

    1974-01-01

    The various types of meteorological satellites are enumerated. Vertical sounding, parameter extraction technique, and both macroscale and mesoscale meteorological phenomena are discussed. The heat budget of the earth-atmosphere system is considered, along with ocean surface and hydrology.

  18. A Wealth of Accomplishments.

    ERIC Educational Resources Information Center

    McDaniel, Lynda

    2000-01-01

    In Hale County, Alabama, a strong spirit of community collaboration led to the development of a family resource center that provides preschool education, a drug prevention program, center-based and mobile health services, general equivalency diploma (GED) classes, outreach services, and a youth leadership program in which outstanding high school…

  19. Riocell nurtures environmental accomplishments

    SciTech Connect

    Meadows, D.G.

    1994-05-01

    Environmental concerns have very much influenced operations at Riocell's pulp and paper mill in Guaiba, Brazil. Celso Foelkel, environmental and technical director, refers to it as a minimal environmental impact mill that's moving toward becoming a zero impact mill. In many cases, Riocell has developed simple methods to reduce or recycle 99.7% of the 15,000 tons/month of solid residue it generates. It uses composted mill waste to renourish the soil of its plantations, though most of the organic fertilizer produced is sold to local farmers for agricultural use. About half of the solid residue is converted to agricultural use, especially as organic fertilizers. Sawdust is used as fuel or as bedding for poultry. Another 40% goes to industrial uses such as cement manufacturing. The rest is used as fill for the recovery of mined areas. Event the garbage from the mill is sorted and 85% is recycled. A new concern for the Riocell mill is a move toward placing taxes on the use of natural resources such as water. That's prompted the mill to look into going a step beyond tertiary treatment. The Clean-Rio process makes use of sand-bed filtration and reverse osmosis. Settling with activated carbon might also work well.

  20. Identifying 21st Century Capabilities

    ERIC Educational Resources Information Center

    Stevens, Robert

    2012-01-01

    What are the capabilities necessary to meet 21st century challenges? Much of the literature on 21st century skills focuses on skills necessary to meet those challenges associated with future work in a globalised world. The result is a limited characterisation of those capabilities necessary to address 21st century social, health and particularly…

  1. NASA Space Rocket Logistics Challenges

    NASA Technical Reports Server (NTRS)

    Neeley, James R.; Jones, James V.; Watson, Michael D.; Bramon, Christopher J.; Inman, Sharon K.; Tuttle, Loraine

    2014-01-01

    The Space Launch System (SLS) is the new NASA heavy lift launch vehicle and is scheduled for its first mission in 2017. The goal of the first mission, which will be uncrewed, is to demonstrate the integrated system performance of the SLS rocket and spacecraft before a crewed flight in 2021. SLS has many of the same logistics challenges as any other large scale program. Common logistics concerns for SLS include integration of discreet programs geographically separated, multiple prime contractors with distinct and different goals, schedule pressures and funding constraints. However, SLS also faces unique challenges. The new program is a confluence of new hardware and heritage, with heritage hardware constituting seventy-five percent of the program. This unique approach to design makes logistics concerns such as commonality especially problematic. Additionally, a very low manifest rate of one flight every four years makes logistics comparatively expensive. That, along with the SLS architecture being developed using a block upgrade evolutionary approach, exacerbates long-range planning for supportability considerations. These common and unique logistics challenges must be clearly identified and tackled to allow SLS to have a successful program. This paper will address the common and unique challenges facing the SLS programs, along with the analysis and decisions the NASA Logistics engineers are making to mitigate the threats posed by each.

  2. Identifying Turbulent Structures through Topological Segmentation

    SciTech Connect

    Bremer, Peer-Timo; Gruber, Andrea; Bennett, Janine C.; Gyulassy, Attila; Kolla, Hemanth; Chen, Jacqueline H.; Grout, Ray W.

    2016-01-01

    A new method of extracting vortical structures from a turbulent flow is proposed whereby topological segmentation of an indicator function scalar field is used to identify the regions of influence of the individual vortices. This addresses a long-standing challenge in vector field topological analysis: indicator functions commonly used produce a scalar field based on the local velocity vector field; reconstructing regions of influence for a particular structure requires selecting a threshold to define vortex extent. In practice, the same threshold is rarely meaningful throughout a given flow. By also considering the topology of the indicator field function, the characteristics of vortex strength and extent can be separated and the ambiguity in the choice of the threshold reduced. The proposed approach is able to identify several types of vortices observed in a jet in cross-flow configuration simultaneously where no single threshold value for a selection of common indicator functions appears able to identify all of these vortex types.

  3. SPARQL-enabled identifier conversion with Identifiers.org

    PubMed Central

    Wimalaratne, Sarala M.; Bolleman, Jerven; Juty, Nick; Katayama, Toshiaki; Dumontier, Michel; Redaschi, Nicole; Le Novère, Nicolas; Hermjakob, Henning; Laibe, Camille

    2015-01-01

    Motivation: On the semantic web, in life sciences in particular, data is often distributed via multiple resources. Each of these sources is likely to use their own International Resource Identifier for conceptually the same resource or database record. The lack of correspondence between identifiers introduces a barrier when executing federated SPARQL queries across life science data. Results: We introduce a novel SPARQL-based service to enable on-the-fly integration of life science data. This service uses the identifier patterns defined in the Identifiers.org Registry to generate a plurality of identifier variants, which can then be used to match source identifiers with target identifiers. We demonstrate the utility of this identifier integration approach by answering queries across major producers of life science Linked Data. Availability and implementation: The SPARQL-based identifier conversion service is available without restriction at http://identifiers.org/services/sparql. Contact: sarala@ebi.ac.uk PMID:25638809

  4. Managing Adaptive Challenges: Learning with Principals in Bermuda and Florida

    ERIC Educational Resources Information Center

    Drago-Severson, Eleanor; Maslin-Ostrowski, Patricia; Hoffman, Alexander M.; Barbaro, Justin

    2014-01-01

    We interviewed eight principals from Bermuda and Florida about how they identify and manage their most pressing challenges. Their challenges are composed of both adaptive and technical work, requiring leaders to learn to diagnose and manage them. Challenges focused on change and were traced to accountability contexts, yet accountability was not…

  5. An Exploration of Challenges Facing Division III Athletic Directors

    ERIC Educational Resources Information Center

    Engbers, Jeffrey L.

    2011-01-01

    The purpose of this study was to establish a basic understanding of the challenges associated with directing athletic programs at NCAA Division III Institutions. Specifically, this study identified the frequency, intensity, and time allocated to common challenges facing the position of the NCAA Division III AD. The challenges were examined using…

  6. Big Data and Analytics in Higher Education: Opportunities and Challenges

    ERIC Educational Resources Information Center

    Daniel, Ben

    2015-01-01

    Institutions of higher education are operating in an increasingly complex and competitive environment. This paper identifies contemporary challenges facing institutions of higher education worldwide and explores the potential of Big Data in addressing these challenges. The paper then outlines a number of opportunities and challenges associated…

  7. Influence of "Mood-Inducing" Music on Challenging Behavior.

    ERIC Educational Resources Information Center

    Durand, V. Mark; Mapstone, Eileen

    1998-01-01

    Two studies examined the effects of musical manipulation on the challenging behaviors of two children and one adult with severe/profound mental retardation. First, high-rate challenging behaviors were identified and then fast- or slow-beat music was added. Challenging behavior was more frequent when slow-beat music was played. Affect also varied…

  8. Challenges Faced by Maine School Districts in Providing High Quality Public Education. Research Brief

    ERIC Educational Resources Information Center

    Silvernail, David L.; Linet, Sarah R.

    2014-01-01

    The goal of this study was to: (1) identify challenges faced by Maine school districts in providing high quality public education; (2) describe the magnitude of the challenges; and (3) identify areas where school districts were experiencing some success in meeting these challenges. The School Districts Challenge Survey was distributed online to…

  9. NASA Centennial Challenges: After the Challenge

    NASA Video Gallery

    What's it like to participate in a NASA Centennial Challenge? In their own words: "We really had no idea what to expect when we got here. Being able to take all of this...now we have an idea for ne...

  10. Challenging Behaviour: A Challenge To Change.

    ERIC Educational Resources Information Center

    van Berckelaer-Onnes, I. A.; van Loon, J.; Peelen, A.

    2002-01-01

    This article discusses the role in the Netherlands of independent regional advisory teams made up of professionals who have experience with individuals who exhibit challenging behaviors. One team's methods are illustrated by describing the case of a completely isolated 24-year-old man who, after a 7-year intervention, was able to fulfill a long…

  11. Addressing Global Data Sharing Challenges.

    PubMed

    Alter, George C; Vardigan, Mary

    2015-07-01

    This issue of the Journal of Empirical Research on Human Research Ethics highlights the ethical issues that arise when researchers conducting projects in low- and middle-income countries seek to share the data they produce. Although sharing data is considered a best practice, the barriers to doing so are considerable and there is a need for guidance and examples. To that end, the authors of this article reviewed the articles in this special issue to identify challenges common to the five countries and to offer some practical advice to assist researchers in navigating this "uncharted territory," as some termed it. Concerns around informed consent, data management, data dissemination, and validation of research contributions were cited frequently as particularly challenging areas, so the authors focused on these four topics with the goal of providing specific resources to consult as well as examples of successful projects attempting to solve many of the problems raised. PMID:26297753

  12. Smart textiles: Challenges and opportunities

    NASA Astrophysics Data System (ADS)

    Cherenack, Kunigunde; van Pieterson, Liesbeth

    2012-11-01

    Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. A key driver for smart textiles research is the fact that both textile and electronics fabrication processes are capable of functionalizing large-area surfaces at very high speeds. In this article we review the history of smart textiles development, introducing the main trends and technological challenges faced in this field. Then, we identify key challenges that are the focus of ongoing research. We then proceed to discuss fundamentals of smart textiles: textile fabrication methods and textile interconnect lines, textile sensor, and output device components and integration of commercial components into textile architectures. Next we discuss representative smart textile systems and finally provide our outlook over the field and a prediction for the future.

  13. The Higgs Machine Learning Challenge

    NASA Astrophysics Data System (ADS)

    Adam-Bourdarios, C.; Cowan, G.; Germain-Renaud, C.; Guyon, I.; Kégl, B.; Rousseau, D.

    2015-12-01

    The Higgs Machine Learning Challenge was an open data analysis competition that took place between May and September 2014. Samples of simulated data from the ATLAS Experiment at the LHC corresponding to signal events with Higgs bosons decaying to τ+τ- together with background events were made available to the public through the website of the data science organization Kaggle (kaggle.com). Participants attempted to identify the search region in a space of 30 kinematic variables that would maximize the expected discovery significance of the signal process. One of the primary goals of the Challenge was to promote communication of new ideas between the Machine Learning (ML) and HEP communities. In this regard it was a resounding success, with almost 2,000 participants from HEP, ML and other areas. The process of understanding and integrating the new ideas, particularly from ML into HEP, is currently underway.

  14. Addressing Global Data Sharing Challenges

    PubMed Central

    Alter, George C.

    2015-01-01

    This issue of the Journal of Empirical Research on Human Research Ethics highlights the ethical issues that arise when researchers conducting projects in low- and middle-income countries seek to share the data they produce. Although sharing data is considered a best practice, the barriers to doing so are considerable and there is a need for guidance and examples. To that end, the authors of this article reviewed the articles in this special issue to identify challenges common to the five countries and to offer some practical advice to assist researchers in navigating this “uncharted territory,” as some termed it. Concerns around informed consent, data management, data dissemination, and validation of research contributions were cited frequently as particularly challenging areas, so the authors focused on these four topics with the goal of providing specific resources to consult as well as examples of successful projects attempting to solve many of the problems raised. PMID:26297753

  15. Chip Scale Package Implementation Challenges

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    1998-01-01

    The JPL-led MicrotypeBGA Consortium of enterprises representing government agencies and private companies have jointed together to pool in-kind resources for developing the quality and reliability of chip scale packages (CSPs) for a variety of projects. In the process of building the Consortium CSP test vehicles, many challenges were identified regarding various aspects of technology implementation. This paper will present our experience in the areas of technology implementation challenges, including design and building both standard and microvia boards, and assembly of two types of test vehicles. We also discuss the most current package isothermal aging to 2,000 hours at 100 C and 125 C and thermal cycling test results to 1,700 cycles in the range of -30 to 100 C.

  16. Bacterial challenges in food

    PubMed Central

    Collee, J. G.

    1974-01-01

    Qualitative and quantitative aspects of bacterial challenges that might be encountered in food are discussed with reference to recognized and relatively unrecognized hazards. Mechanisms of pathogenicity are reviewed and the populations at risk are noted. The bacterial content of food as it is served at table merits more study. The challenge of prevention by education is discussed. Indirect bacterial challenges in our food are considered. The real challenge of diagnosis depends upon an awareness of a complex range of conditions; the importance of effective communication with efficient laboratory and epidemiological services is stressed. There is an increasing need for care in the preparation and distribution of food. PMID:4467860

  17. NASA Exploration Design Challenge

    NASA Video Gallery

    From the International Space Station, astronaut Sunita Williams welcomes participants to the NASA Exploration Design Challenge and explains the uncertainties about the effects of space radiation on...

  18. Exploiting intrinsic fluctuations to identify model parameters.

    PubMed

    Zimmer, Christoph; Sahle, Sven; Pahle, Jürgen

    2015-04-01

    Parameterisation of kinetic models plays a central role in computational systems biology. Besides the lack of experimental data of high enough quality, some of the biggest challenges here are identification issues. Model parameters can be structurally non-identifiable because of functional relationships. Noise in measured data is usually considered to be a nuisance for parameter estimation. However, it turns out that intrinsic fluctuations in particle numbers can make parameters identifiable that were previously non-identifiable. The authors present a method to identify model parameters that are structurally non-identifiable in a deterministic framework. The method takes time course recordings of biochemical systems in steady state or transient state as input. Often a functional relationship between parameters presents itself by a one-dimensional manifold in parameter space containing parameter sets of optimal goodness. Although the system's behaviour cannot be distinguished on this manifold in a deterministic framework it might be distinguishable in a stochastic modelling framework. Their method exploits this by using an objective function that includes a measure for fluctuations in particle numbers. They show on three example models, immigration-death, gene expression and Epo-EpoReceptor interaction, that this resolves the non-identifiability even in the case of measurement noise with known amplitude. The method is applied to partially observed recordings of biochemical systems with measurement noise. It is simple to implement and it is usually very fast to compute. This optimisation can be realised in a classical or Bayesian fashion. PMID:26672148

  19. Connecting Research and Researchers: ORCID Identifiers (Invited)

    NASA Astrophysics Data System (ADS)

    Haak, L.; Bryant, R.

    2013-12-01

    Lack of standards for identification of researchers is a major challenge for the research community. It is difficult not only to unambiguously associate researchers with their own work, but also to track use and re-use of those works. The goal of ORCID (orcid.org) is to connect research with researchers, ultimately saving researchers time in entering data, improving discoverability, and facilitating the flow of research information and data re-use. ORCID is a community-driven non-profit organization that provides an open registry of unique persistent identifiers for researchers. We work collaboratively with the research community to embed these identifiers in research workflows, including manuscript submission, grant application, and data set deposit. In this presentation, we will provide an overview of ORCID, an in particular how it is being used as a switchboard to connect existing but fragmented researcher identifiers. ORCID also provides researchers search and link tools to link their ORCID identifier to their existing datasets, grants, other research works, and an automated method to link new works to their identifier. ORCID is fundamental to solving the name ambiguity problem for researchers and scholars. Together with unique and persistent identifiers for publications, data sets, and research samples, ORCID is an essential underpinning needed to support interoperability between research systems.

  20. Automated igneous rock identifiers for Mars Exploration

    NASA Astrophysics Data System (ADS)

    Gulick, V. C.; Morris, R. L.; Gazis, P.; Bishop, J. L.; Alena, R.; Hart, S. D.; Horton, A.

    2003-04-01

    A key task for human or robotic explorers on the surface of Mars is choosing which particular rock or mineral samples should be selected for more intensive study. The usual challenges of such a task are compounded by the lack of sensory input available to a suited astronaut or the limited downlink bandwidth available to a rover. Additional challenges facing a human mission include limited surface time and the similarities in appearance of important minerals (e.g. carbonates, silicates, salts). Yet the choice of which sample to collect is critical. To address this challenge we are developing science analysis algorithms to interface with a Geologist's Field Assistant (GFA) device that will allow robotic or human remote explorers to better sense and explore their surroundings during limited surface excursions [1]. We aim for our algorithms to interpret spectral and imaging data obtained by various sensors. Our algorithms, for example, will identify key minerals, rocks, and sediments from mid-IR, Raman, and visible/near-IR spectra as well as from high-resolution and microscopic images to help interpret data and to provide high-level advice to the remote explorer. A top-level system will consider multiple inputs from raw sensor data output by imagers and spectrometers (visible/near-IR, mid-IR, and Raman) as well as human opinion to identify rock and mineral samples. Our prototype image analysis system identifies some igneous rocks from texture and color information. Spectral analysis algorithms have also been developed that successfully identify quartz, silica polymorphs, calcite, pyroxene, and jarosite from both visible/near-IR and mid-IR spectra. We have also developed spectral recognizers that identify high-iron pyroxenes and iron-bearing minerals using visible/near-IR spectra only. We are building a combined image and spectral database of rocks and minerals with which to continue development of our algorithms. Future plans include developing algorithms to identify

  1. Mars outpost - System and operations challenges

    NASA Technical Reports Server (NTRS)

    Roberts, Barney; Guerra, Lisa

    1990-01-01

    The paper addresses the challenges inherent in establishing an outpost on the planet Mars. For background purposes, the unique, remote Martian environment and the developmental phases of a settlement in such an environment are discussed. Challenges are identified in terms of surface systems and operations. Due to its importance to habitability, the life support system (LSS) is highlighted with various options identified. Operations for the Mars outpost, earth-based and local, are characterized by a decentralized concept. The challenge of integrating logistics analysis early in system design and operations strategy is also addressed. In order to understand and reduce the system and operations challenges, the application of terrestrial and lunar testbeds is explained.

  2. Identifying Internet Sites to Coordinate with National Science Education Standards

    ERIC Educational Resources Information Center

    Fehrenbach, Carolyn R.; Morris, Maxine G.

    2004-01-01

    Identifying Internet sites to coordinate with National Science Education Standards can be challenging for teachers and students. By identifying quality free Internet sites in science, teachers and students can use the extensive resources of the Internet to enhance learning and instruction while meeting National Science Education Content Standards…

  3. Identifying Evidence of Reflective Ability in Preservice Teacher Electronic Portfolios

    ERIC Educational Resources Information Center

    Sulzen, James

    2011-01-01

    Results of this study identified "evidence markers" that characterize reflection in preservice teacher electronic portfolios. Examples of such markers include openness to self-learning, willingness to self-critique, analytical detail of reflections, and taking responsibility for pupil learning challenges. To identify the markers, school of…

  4. Assessment of Aerodynamic Challenges of a Variable-Speed Power Turbine for Large Civil Tilt-Rotor Application

    NASA Technical Reports Server (NTRS)

    Welch, Gerand E.

    2010-01-01

    The main rotors of the NASA Large Civil Tilt-Rotor notional vehicle operate over a wide speed-range (100% at take-off to 54% at cruise). The variable-speed power turbine, when coupled to a fixed-gear-ratio transmission, offers one approach to accomplish this speed variation. The key aero-challenges of the variable-speed power turbine are related to high work factors at cruise, where the power turbine operates at 54% of take-off speed, wide incidence variations into the vane, blade, and exit-guide-vane rows associated with the power-turbine speed change, and the impact of low aft-stage Reynolds number (transitional flow) at 28 kft cruise. Meanline and 2-D Reynolds-Averaged Navier- Stokes analyses are used to characterize the variable-speed power-turbine aerodynamic challenges and to outline a conceptual design approach that accounts for multi-point operation. Identified technical challenges associated with the aerodynamics of high work factor, incidence-tolerant blading, and low Reynolds numbers pose research needs outlined in the paper

  5. Recurrent procedures for calculating numerical indicators of accomplishments of strategic/operational plans at all levels of the organization

    NASA Astrophysics Data System (ADS)

    Pougatchev, Valeri

    2014-12-01

    This paper describes a quantitative measurement approach within an effective and transparent operational/strategic planning framework at all levels of organization, including individuals by linking objectives, initiatives and measures to one holistic organization's strategy. The author has introduced an original parameter V-index that numerically represents the level of accomplishment of strategic/operational plans of the entire organization, its different units, and individual members of staff. The V-index provides a transparency of viewing and effective control of plans of the organization at all levels, with hierarchical and non-hierarchical structures. This parameter facilitates process of year-by-year strategic analysis of the success of the organization and its units by managers. For calculating of actual value of the V-index the author has successfully introduced a recurrent computing algorithm for horizontal/vertical alignment processes of the hierarchical strategic and operational planning.

  6. Overview and recent accomplishments of the advanced mirror technology development (AMTD) for large aperture UVOIR space telescopes project

    NASA Astrophysics Data System (ADS)

    Stahl, H. Philip; Postman, Marc; Abplanalp, Laura; Arnold, William; Eng, Ron; Sivaramakrishnan, Anand

    2013-09-01

    The Advance Mirror Technology Development (AMTD) project is a three year effort initiated in FY12 to mature by at least a half TRL step six critical technologies required to enable 4 to 8 meter UVOIR space telescope primary mirror assemblies for both general astrophysics and ultra-high contrast observations of exoplanets. Thus far, AMTD has achieved all of its goals and accomplished all of its milestones. We did this by assembling an outstanding team from academia, industry, and government with extensive expertise in astrophysics and exoplanet characterization, and in the design/manufacture of monolithic and segmented space telescopes; by deriving engineering specifications for advanced normal-incidence mirror systems needed to make the required science measurements; and by defining and prioritizing the most important technical problems to be solved.

  7. Winds of Change: Expanding the Frontiers of Flight. Langley Research Center's 75 Years of Accomplishment, 1917-1992

    NASA Technical Reports Server (NTRS)

    Schultz, James

    1992-01-01

    This commemorative volume highlights in pictures and text seventy five years of accomplishments of the Langley Research Center. The introductory matter features wind tunnels and their contribution to the development of aeronautics. A chronological survey details four different periods in Langley's history. The first period, 1917-1939, is subtitled 'Perfecting the Plane' which details Langley's contribution to early aeronautics with examples from specific aircraft. The second period, 1940-1957, focuses on the development of military aircraft during and after World War II. The third period, 1958-1969, tells the story of Langley's involvement with NASA and the satellite and Apollo era. The fourth period, entitled 'Charting New Courses: 1970-1992 and Beyond', treats various new topics from aerospace planes to Mars landing, as well as older topics such as the Space Shuttle and research spinoffs.

  8. National Low-Level Waste Management Program final summary report of key activities and accomplishments for fiscal year 1997

    SciTech Connect

    Rittenberg, R.B.

    1998-03-01

    The US Department of Energy (DOE) has responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985 to assist states and compacts in their siting and licensing efforts for low-level radioactive waste disposal facilities. The National Low-Level Waste Management Program (NLLWMP) is the element of the DOE that performs the key support activities under the Act. The NLLWMP`s activities are driven by the needs of the states and compacts as they prepare to manage their low-level waste under the Act. Other work is added during the fiscal year as necessary to accommodate new requests brought on by status changes in states` and compacts` siting and licensing efforts. This report summarizes the activities and accomplishments of the NLLWMP during FY 1997.

  9. Identifying chemicals that are planetary boundary threats.

    PubMed

    MacLeod, Matthew; Breitholtz, Magnus; Cousins, Ian T; de Wit, Cynthia A; Persson, Linn M; Rudén, Christina; McLachlan, Michael S

    2014-10-01

    Rockström et al. proposed a set of planetary boundaries that delimit a "safe operating space for humanity". Many of the planetary boundaries that have so far been identified are determined by chemical agents. Other chemical pollution-related planetary boundaries likely exist, but are currently unknown. A chemical poses an unknown planetary boundary threat if it simultaneously fulfills three conditions: (1) it has an unknown disruptive effect on a vital Earth system process; (2) the disruptive effect is not discovered until it is a problem at the global scale, and (3) the effect is not readily reversible. In this paper, we outline scenarios in which chemicals could fulfill each of the three conditions, then use the scenarios as the basis to define chemical profiles that fit each scenario. The chemical profiles are defined in terms of the nature of the effect of the chemical and the nature of exposure of the environment to the chemical. Prioritization of chemicals in commerce against some of the profiles appears feasible, but there are considerable uncertainties and scientific challenges that must be addressed. Most challenging is prioritizing chemicals for their potential to have a currently unknown effect on a vital Earth system process. We conclude that the most effective strategy currently available to identify chemicals that are planetary boundary threats is prioritization against profiles defined in terms of environmental exposure combined with monitoring and study of the biogeochemical processes that underlie vital Earth system processes to identify currently unknown disruptive effects. PMID:25181298

  10. Interdisciplinary and physics challenges of network theory

    NASA Astrophysics Data System (ADS)

    Bianconi, Ginestra

    2015-09-01

    Network theory has unveiled the underlying structure of complex systems such as the Internet or the biological networks in the cell. It has identified universal properties of complex networks, and the interplay between their structure and dynamics. After almost twenty years of the field, new challenges lie ahead. These challenges concern the multilayer structure of most of the networks, the formulation of a network geometry and topology, and the development of a quantum theory of networks. Making progress on these aspects of network theory can open new venues to address interdisciplinary and physics challenges including progress on brain dynamics, new insights into quantum technologies, and quantum gravity.

  11. Special Issue: The First Provenance Challenge

    SciTech Connect

    Moreau, Luc; Ludaescher, Bertram T.; Altintas, Ilkay; Barga, Roger S.; Bowers, Shawn; Callahan, Steven P.; Chin, George; Clifford, Ben; Cohen, Shirley; Cohen-Boulakia, Sarah; Davidson, Susan; Deelman, Ewa; digiampietri, Luciano; Foster, Ian T.; Freire, Juliana; Frew, James; Futrelle, Joe; Gibson, Tara D.; Gil, Yolanda; Goble, Carole; Golbeck, Jennifer; Groth, Paul; Holland, David A.; Jiang, Sheng; Kim, Jihie; Koop, David; Krenek, Ales; McPhillips, Timothy; Mehta, Gaurang; Miles, Simon; Metzger, Dominic; Munroe, Steve; Myers, James D.; Plale, Beth A.; Podhorszki, norbert; Ratnakar, Varun; Emanuele , Santos; scheidegger, Carlos E.; Schuchardt, Karen L.; Seltzer, Margo I.; Simmhan, Yogesh L.; Claudio, Silva T.; Slaughter, Peter; Stephan, Eric G.; Stevens, Robert; Turi, Daniele; Vo, Huy T.; Wilde, Mike J.; Zhao, Jun; Zhao, Yong

    2008-04-01

    The first Provenance Challenge was set up in order to provide a forum for the community to help understand the capabilities of different provenance systems and the expressiveness of their provenance representations. To this end, a Functional Magnetic Resonance Imaging workflow was defined, which participants had to either simulate or run in order to produce some provenance representation, from which a set of identified queries had to be implemented and executed. Sixteen teams responded to the challenge, and submitted their inputs. In this paper, we present the challenge workflow and queries, and summarise the participants contributions.

  12. Challenges for the aircraft structural integrity program

    NASA Technical Reports Server (NTRS)

    Lincoln, John W.

    1994-01-01

    Thirty-six years ago the United States Air Force established the USAF Aircraft Structural Integrity Program (ASIP) because flight safety had been degraded by fatigue failures of operational aircraft. This initial program evolved, but has been stable since the issuance of MIL-STD-1530A in 1975. Today, the program faces new challenges because of a need to maintain aircraft longer in an environment of reduced funding levels. Also, there is increased pressure to reduce cost of the acquisition of new aircraft. It is the purpose of this paper to discuss the challenges for the ASIP and identify the changes in the program that will meet these challenges in the future.

  13. The Multimedia Challenge.

    ERIC Educational Resources Information Center

    Penuel, William R.; Means, Barbara; Simkins, Michael

    2000-01-01

    Teachers implementing a local history project in Belmont, California, had help from a federally funded technology innovation challenge grant: the Challenge 2000 Multimedia Project. Sponsored by a Silicon Valley school-business partnership, the initiative illustrates how technology can transform classroom learning while supporting instructional…

  14. A Call to Challenge

    ERIC Educational Resources Information Center

    Colleary, Shawn

    2004-01-01

    This article features the Challenge School, a magnet school in the CherryCreek School District in Colorado that focuses on academically advanced, motivated, and gifted students. The school was developed as an alternative to best meet the needs of these students. The Challenge School focuses on high student achievement and commensurate academic…

  15. Virtual Bridge Design Challenge

    ERIC Educational Resources Information Center

    Mitts, Charles R.

    2013-01-01

    This design/problem-solving activity challenges students to design a replacement bridge for one that has been designated as either structurally deficient or functionally obsolete. The Aycock MS Technology/STEM Magnet Program Virtual Bridge Design Challenge is an authentic introduction to the engineering design process. It is a socially relevant…

  16. The Intersection Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2011-01-01

    Street intersections are a source of accidents--for both automobiles and pedestrians. This article presents an intersection challenge that allows students to explore some possible ways to change the traditional intersection. In this challenge, teachers open up the boundaries and allow students to redesign their world. The first step is to help…

  17. Challenges Facing Special Education.

    ERIC Educational Resources Information Center

    Meyen, Edward L., Ed.; And Others

    This book presents 17 selected papers from recent issues of the journal, "Focus on Exceptional Children," concerning current and emerging challenges facing the field of special education. The book is organized in two parts. Part 1, "Contemporary Challenges," includes the following articles: "Transitions in Early Childhood Special Education: Issues…

  18. Challenges and Roadblocks

    ERIC Educational Resources Information Center

    Hargrove, Kathy

    2011-01-01

    Gifted education has many challenges, and gifted programs sometimes throw up significant roadblocks. But passionate teachers can still make a difference in developing the gifts of the children. In this article, the author summarizes the challenges teachers face in serving gifted students and the roadblocks preventing a strong, supportive gifted…

  19. Science Challenge Day

    ERIC Educational Resources Information Center

    Siegel, Deborah

    2013-01-01

    Science fairs can be good motivators, but as extracurricular activities, they leave some students behind. However, by staging a Science Challenge Day at school, educators can involve all students in doing everything from choosing activities to judging projects. This article presents a model for running a successful Science Challenge Day. The…

  20. First Aid Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2011-01-01

    This article describes a challenge wherein students will be asked to design a portable first aid kit that is normally carried in a recreational vehicle (RV), but can also be hand-carried or backpacked off road for distances of approximately 1-2 miles. This can be a very practical challenge for the students because it touches everyone. Everybody…