Phase-function normalization for accurate analysis of ultrafast collimated radiative transfer.
Hunter, Brian; Guo, Zhixiong
2012-04-20
The scattering of radiation from collimated irradiation is accurately treated via normalization of phase function. This approach is applicable to any numerical method with directional discretization. In this study it is applied to the transient discrete-ordinates method for ultrafast collimated radiative transfer analysis in turbid media. A technique recently developed by the authors, which conserves a phase-function asymmetry factor as well as scattered energy for the Henyey-Greenstein phase function in steady-state diffuse radiative transfer analysis, is applied to the general Legendre scattering phase function in ultrafast collimated radiative transfer. Heat flux profiles in a model tissue cylinder are generated for various phase functions and compared to those generated when normalization of the collimated phase function is neglected. Energy deposition in the medium is also investigated. Lack of conservation of scattered energy and the asymmetry factor for the collimated scattering phase function causes overpredictions in both heat flux and energy deposition for highly anisotropic scattering media. In addition, a discussion is presented to clarify the time-dependent formulation of divergence of radiative heat flux. PMID:22534933
Marelli, Damián; Baumgartner, Robert; Majdak, Piotr
2015-01-01
Head-related transfer functions (HRTFs) describe the acoustic filtering of incoming sounds by the human morphology and are essential for listeners to localize sound sources in virtual auditory displays. Since rendering complex virtual scenes is computationally demanding, we propose four algorithms for efficiently representing HRTFs in subbands, i.e., as an analysis filterbank (FB) followed by a transfer matrix and a synthesis FB. All four algorithms use sparse approximation procedures to minimize the computational complexity while maintaining perceptually relevant HRTF properties. The first two algorithms separately optimize the complexity of the transfer matrix associated to each HRTF for fixed FBs. The other two algorithms jointly optimize the FBs and transfer matrices for complete HRTF sets by two variants. The first variant aims at minimizing the complexity of the transfer matrices, while the second one does it for the FBs. Numerical experiments investigate the latency-complexity trade-off and show that the proposed methods offer significant computational savings when compared with other available approaches. Psychoacoustic localization experiments were modeled and conducted to find a reasonable approximation tolerance so that no significant localization performance degradation was introduced by the subband representation. PMID:26681930
Ratcliff, Laura E; Grisanti, Luca; Genovese, Luigi; Deutsch, Thierry; Neumann, Tobias; Danilov, Denis; Wenzel, Wolfgang; Beljonne, David; Cornil, Jérôme
2015-05-12
A fast and accurate scheme has been developed to evaluate two key molecular parameters (on-site energies and transfer integrals) that govern charge transport in organic supramolecular architecture devices. The scheme is based on a constrained density functional theory (CDFT) approach implemented in the linear-scaling BigDFT code that exploits a wavelet basis set. The method has been applied to model disordered structures generated by force-field simulations. The role of the environment on the transport parameters has been taken into account by building large clusters around the active molecules involved in the charge transfer. PMID:26574411
NASA Technical Reports Server (NTRS)
Taback, I.
1979-01-01
The vulnerability of electronic equipment to carbon fibers is studied. The effectiveness of interfaces, such as filters, doors, window screens, and cabinets, which affect the concentration, exposure, or deposition of carbon fibers on both (internal and external) sides of the interface is examined. The transfer function of multilayer aluminum mesh, wet and dry, polyurethane foam, and window screen are determined as a function of air velocity. FIlters installed in typical traffic control boxes and air conditioners are also considered.
Accurate radiative transfer calculations for layered media.
Selden, Adrian C
2016-07-01
Simple yet accurate results for radiative transfer in layered media with discontinuous refractive index are obtained by the method of K-integrals. These are certain weighted integrals applied to the angular intensity distribution at the refracting boundaries. The radiative intensity is expressed as the sum of the asymptotic angular intensity distribution valid in the depth of the scattering medium and a transient term valid near the boundary. Integrated boundary equations are obtained, yielding simple linear equations for the intensity coefficients, enabling the angular emission intensity and the diffuse reflectance (albedo) and transmittance of the scattering layer to be calculated without solving the radiative transfer equation directly. Examples are given of half-space, slab, interface, and double-layer calculations, and extensions to multilayer systems are indicated. The K-integral method is orders of magnitude more accurate than diffusion theory and can be applied to layered scattering media with a wide range of scattering albedos, with potential applications to biomedical and ocean optics. PMID:27409700
Accurate density functional thermochemistry for larger molecules.
Raghavachari, K.; Stefanov, B. B.; Curtiss, L. A.; Lucent Tech.
1997-06-20
Density functional methods are combined with isodesmic bond separation reaction energies to yield accurate thermochemistry for larger molecules. Seven different density functionals are assessed for the evaluation of heats of formation, Delta H 0 (298 K), for a test set of 40 molecules composed of H, C, O and N. The use of bond separation energies results in a dramatic improvement in the accuracy of all the density functionals. The B3-LYP functional has the smallest mean absolute deviation from experiment (1.5 kcal mol/f).
Accurate momentum transfer cross section for the attractive Yukawa potential
Khrapak, S. A.
2014-04-15
Accurate expression for the momentum transfer cross section for the attractive Yukawa potential is proposed. This simple analytic expression agrees with the numerical results better than to within ±2% in the regime relevant for ion-particle collisions in complex (dusty) plasmas.
Goulding, J.R. )
1991-01-01
This paper details the approach and methodology used to build adaptive transfer functions in a feed-forward Back-Propagation neural network, and provides insight into the structure dependent properties of using non-scaled analog inputs. The results of using adaptive transfer functions are shown to outperform conventional architectures in the implementation of a mechanical power transmission gearbox design expert system knowledge base. 4 refs., 4 figs., 1 tab.
NASA Technical Reports Server (NTRS)
Seraji, H.
1987-01-01
Given a multivariable system, it is proved that the numerator matrix N(s) of the transfer function evaluated at any system pole either has unity rank or is a null matrix. It is also shown that N(s) evaluated at any transmission zero of the system has rank deficiency. Examples are given for illustration.
Adaptive Transfer Function Networks
Goulding, J.R. |
1993-06-01
Real-time pattern classification and time-series forecasting applications continue to drive artificial neural network (ANN) technology. As ANNs increase in complexity, the throughput of digital computer simulations decreases. A novel ANN, the Adaptive Transfer Function Network (ATF-Net), directly addresses the issue of throughput. ATF-Nets are global mapping equations generated by the superposition of ensembles of neurodes having arbitrary continuous functions receiving encoded input data. ATF-Nets may be implemented on parallel digital computers. An example is presented which illustrates a four-fold increase in computational throughput.
Adaptive Transfer Function Networks
Goulding, J.R. Portland State Univ., OR . Dept. of Electrical Engineering)
1993-01-01
Real-time pattern classification and time-series forecasting applications continue to drive artificial neural network (ANN) technology. As ANNs increase in complexity, the throughput of digital computer simulations decreases. A novel ANN, the Adaptive Transfer Function Network (ATF-Net), directly addresses the issue of throughput. ATF-Nets are global mapping equations generated by the superposition of ensembles of neurodes having arbitrary continuous functions receiving encoded input data. ATF-Nets may be implemented on parallel digital computers. An example is presented which illustrates a four-fold increase in computational throughput.
A spectroscopic transfer standard for accurate atmospheric CO measurements
NASA Astrophysics Data System (ADS)
Nwaboh, Javis A.; Li, Gang; Serdyukov, Anton; Werhahn, Olav; Ebert, Volker
2016-04-01
Atmospheric carbon monoxide (CO) is a precursor of essential climate variables and has an indirect effect for enhancing global warming. Accurate and reliable measurements of atmospheric CO concentration are becoming indispensable. WMO-GAW reports states a compatibility goal of ±2 ppb for atmospheric CO concentration measurements. Therefore, the EMRP-HIGHGAS (European metrology research program - high-impact greenhouse gases) project aims at developing spectroscopic transfer standards for CO concentration measurements to meet this goal. A spectroscopic transfer standard would provide results that are directly traceable to the SI, can be very useful for calibration of devices operating in the field, and could complement classical gas standards in the field where calibration gas mixtures in bottles often are not accurate, available or stable enough [1][2]. Here, we present our new direct tunable diode laser absorption spectroscopy (dTDLAS) sensor capable of performing absolute ("calibration free") CO concentration measurements, and being operated as a spectroscopic transfer standard. To achieve the compatibility goal stated by WMO for CO concentration measurements and ensure the traceability of the final concentration results, traceable spectral line data especially line intensities with appropriate uncertainties are needed. Therefore, we utilize our new high-resolution Fourier-transform infrared (FTIR) spectroscopy CO line data for the 2-0 band, with significantly reduced uncertainties, for the dTDLAS data evaluation. Further, we demonstrate the capability of our sensor for atmospheric CO measurements, discuss uncertainty calculation following the guide to the expression of uncertainty in measurement (GUM) principles and show that CO concentrations derived using the sensor, based on the TILSAM (traceable infrared laser spectroscopic amount fraction measurement) method, are in excellent agreement with gravimetric values. Acknowledgement Parts of this work have been
Transfer Function Identification Using Orthogonal Fourier Transform Modeling Functions
NASA Technical Reports Server (NTRS)
Morelli, Eugene A.
2013-01-01
A method for transfer function identification, including both model structure determination and parameter estimation, was developed and demonstrated. The approach uses orthogonal modeling functions generated from frequency domain data obtained by Fourier transformation of time series data. The method was applied to simulation data to identify continuous-time transfer function models and unsteady aerodynamic models. Model fit error, estimated model parameters, and the associated uncertainties were used to show the effectiveness of the method for identifying accurate transfer function models from noisy data.
Automated generation of highly accurate, efficient and transferable pseudopotentials
NASA Astrophysics Data System (ADS)
Hansel, R. A.; Brock, C. N.; Paikoff, B. C.; Tackett, A. R.; Walker, D. G.
2015-11-01
A multi-objective genetic algorithm (MOGA) was used to automate a search for optimized pseudopotential parameters. Pseudopotentials were generated using the atomPAW program and density functional theory (DFT) simulations were conducted using the pwPAW program. The optimized parameters were the cutoff radius and projector energies for the s and p orbitals. The two objectives were low pseudopotential error and low computational work requirements. The error was determined from (1) the root mean square difference between the all-electron and pseudized-electron log derivative, (2) the calculated lattice constant versus reference data of Holzwarth et al., and (3) the calculated bulk modulus versus reference potentials. The computational work was defined as the number of flops required to perform the DFT simulation. Pseudopotential transferability was encouraged by optimizing each element in different lattices: (1) nitrogen in GaN, AlN, and YN, (2) oxygen in NO, ZnO, and SiO4, and (3) fluorine in LiF, NaF, and KF. The optimal solutions were equivalent in error and required significantly less computational work than the reference data. This proof-of-concept study demonstrates that the combination of MOGA and ab-initio simulations is a powerful tool that can generate a set of transferable potentials with a trade-off between accuracy (error) and computational efficiency (work).
Operationalizing the Transfer Function.
ERIC Educational Resources Information Center
Garcia, Philip
In statistical terms, transfer rates require two components: a numerator that represents community college students who transfer and a denominator that approximates the pool of potential transfer students. The California Task Force adopted a set of criteria to judge the appropriateness of prospective pairs of numerators and denominators. Its form…
Free Flap Functional Muscle Transfers.
Garcia, Ryan M; Ruch, David S
2016-08-01
Free functional muscle transfers remain a powerful reconstructive tool to restore upper extremity function when other options such as tendon or nerve transfers are not available. This reconstructive technique is commonly used for patients following trauma, ischemic contractures, and brachial plexopathies. Variable outcomes have been reported following free functional muscle transfers that are related to motor nerve availability and reinnervation. This article highlights considerations around donor motor nerve selection, dissection, and use of the gracilis muscle, and the surgical approach to performing a free functional muscle transfer to restore elbow flexion and/or digit flexion. PMID:27387083
Combination of TWSTFT and GNSS for accurate UTC time transfer
NASA Astrophysics Data System (ADS)
Jiang, Z.; Petit, G.
2009-06-01
The international UTC/TAI time and frequency transfer network is based on two independent space techniques: Two-Way Satellite Time and Frequency Transfer (TWSTFT) and Global Navigation Satellite System (GNSS). The network is highly redundant. In fact, 28% of the national time laboratories, which contribute 88% of the total atomic clock weight and all the primary frequency standards to UTC/TAI, operate both techniques. This redundancy is not fully used in UTC/TAI generation. We propose a combination that keeps the advantages of TWSTFT and GNSS and offers a new and effective strategy to improve UTC/TAI in terms of accuracy, stability and robustness. We focus on the combination of two BIPM routine products, TWSTFT and GPS PPP (time transfer using the precise point positioning technique), but the proposed method can be used for any carrier phase-based GNSS product.
Accurate transfer of soft tissue morphology with interim prosthesis to definitive cast.
Noh, Kwantae; Kwon, Kung-Rock; Kim, Hyeong-Seob; Kim, Duck-Su; Pae, Ahran
2014-02-01
With conventional fixed dental prostheses, the interim restoration is a valuable diagnostic tool in the evaluation of esthetics and function. To achieve predictable definitive esthetic results, information about the subgingival and the supragingival contour of a properly designed restoration should be communicated to the dental laboratory technician. The technique described enables the accurate transfer of the soft tissue morphology developed with an interim prosthesis to the definitive cast. This modified definitive cast allows the dental laboratory technician to fabricate a restoration with an emergence profile identical to that of the interim prosthesis. PMID:24286639
Automatic computation of transfer functions
Atcitty, Stanley; Watson, Luke Dale
2015-04-14
Technologies pertaining to the automatic computation of transfer functions for a physical system are described herein. The physical system is one of an electrical system, a mechanical system, an electromechanical system, an electrochemical system, or an electromagnetic system. A netlist in the form of a matrix comprises data that is indicative of elements in the physical system, values for the elements in the physical system, and structure of the physical system. Transfer functions for the physical system are computed based upon the netlist.
Accurate perception of negative emotions predicts functional capacity in schizophrenia.
Abram, Samantha V; Karpouzian, Tatiana M; Reilly, James L; Derntl, Birgit; Habel, Ute; Smith, Matthew J
2014-04-30
Several studies suggest facial affect perception (FAP) deficits in schizophrenia are linked to poorer social functioning. However, whether reduced functioning is associated with inaccurate perception of specific emotional valence or a global FAP impairment remains unclear. The present study examined whether impairment in the perception of specific emotional valences (positive, negative) and neutrality were uniquely associated with social functioning, using a multimodal social functioning battery. A sample of 59 individuals with schizophrenia and 41 controls completed a computerized FAP task, and measures of functional capacity, social competence, and social attainment. Participants also underwent neuropsychological testing and symptom assessment. Regression analyses revealed that only accurately perceiving negative emotions explained significant variance (7.9%) in functional capacity after accounting for neurocognitive function and symptoms. Partial correlations indicated that accurately perceiving anger, in particular, was positively correlated with functional capacity. FAP for positive, negative, or neutral emotions were not related to social competence or social attainment. Our findings were consistent with prior literature suggesting negative emotions are related to functional capacity in schizophrenia. Furthermore, the observed relationship between perceiving anger and performance of everyday living skills is novel and warrants further exploration. PMID:24524947
Easy Accurate Transfer of the Sculpted Soft Tissue Contours to the Working Cast: A Clinical Tip.
Jambhekar, Shantanu S; Kheur, Mohit G; Matani, Jay; Sethi, Sumit
2014-12-01
Tooth replacement in the esthetic zone presents a myriad of challenges for the clinician. An ovate pontic accurately duplicates the emergence profile of the natural tooth it replaces in order to provide an esthetic, yet cleansable prosthesis. The accurate transfer of this sculpted tissue beneath the pontic of the provisional restoration is critical to provide the dental laboratory technician with the necessary information to fabricate a definitive restoration with an appropriate emergence profile. This article presents an innovative, simple and convenient impression technique for easy and accurate transfer of the tissue contours to the working cast, avoiding tissue collapse and tissue compression produced due to the impression material. PMID:26199543
Molecular adsorption at Pt(111). How accurate are DFT functionals?
Gautier, Sarah; Steinmann, Stephan N; Michel, Carine; Fleurat-Lessard, Paul; Sautet, Philippe
2015-11-21
Molecular chemisorption at a metal surface is a key step for many processes, such as catalysis, electrochemistry, surface treatment, tribology and friction. Modeling with density functional theory is largely used on these systems. From a detailed comparison with accurate micro-calorimetric data on ten systems (involving ethylene, cyclohexene, benzene, naphthalene, CO, O2, H2, methane, ethane), we study the accuracy, for chemisorption on Pt(111), of five exchange-correlation functionals including one generalized gradient approximation functional (PBE) and four functionals that take into account van der Waals interactions (optPBE-vdW, optB86b-vdW, BEEF-vdW, PBE-dDsC). If the functionals used provide very similar geometries and electronic structures, as shown by projected density of states, they give strikingly different results for the adsorption energy of molecules on Pt(111). Among the set of chemisorption data, the lowest mean absolute deviations (MAD) are obtained with the optPBE-vdW and PBE-dDsC functionals (∼0.2 eV) while PBE and optB86b-vdW give twice larger MAD (∼0.45 eV). BEEF-vdW is intermediate with a MAD of 0.33 eV. For laterally π-bound unsaturated hydrocarbons (cyclohexene, benzene, naphthalene) the PBE and the BEEF-vdW functionals are severally under-bound, while optPBE-vdW and PBE-dDsC provide a good match with experiments. Hence both the incorporation of van der Waals dispersive forces and the choice of the exchange functional have a key influence on the chemisorption energy. Vertically bound ethylidyne and CO are in contrast over-bound with all functionals, the best agreement being obtained with BEEF-vdW. None of the selected functionals hence provides a universally accurate treatment of chemisorption energies. PMID:26455444
Accurate bs and w testing important for crude-oil custody transfer
Williams, J. )
1990-11-12
This paper discusses how monitoring crude-oil sediment and water content at the field production site is essential in accurate crude-oil custody transfer operations. This is accomplished by manual methods, or on-line devices like capacitance, density, or energy-absorption analyzers. For custody-transfer purposes, sediment and water is determined by a test which follows one of the API manuals of petroleum measurement standards (MPMS). Typically, this test is conducted in the field by the field centrifuge method which, if performed properly, yields very accurate results. Laboratory tests can be performed, but sample handling becomes even more critical.
A novel approach for accurate radiative transfer in cosmological hydrodynamic simulations
NASA Astrophysics Data System (ADS)
Petkova, Margarita; Springel, Volker
2011-08-01
We present a numerical implementation of radiative transfer based on an explicitly photon-conserving advection scheme, where radiative fluxes over the cell interfaces of a structured or unstructured mesh are calculated with a second-order reconstruction of the intensity field. The approach employs a direct discretization of the radiative transfer equation in Boltzmann form with adjustable angular resolution that, in principle, works equally well in the optically-thin and optically-thick regimes. In our most general formulation of the scheme, the local radiation field is decomposed into a linear sum of directional bins of equal solid angle, tessellating the unit sphere. Each of these 'cone fields' is transported independently, with constant intensity as a function of the direction within the cone. Photons propagate at the speed of light (or optionally using a reduced speed of light approximation to allow larger time-steps), yielding a fully time-dependent solution of the radiative transfer equation that can naturally cope with an arbitrary number of sources, as well as with scattering. The method casts sharp shadows, subject to the limitations induced by the adopted angular resolution. If the number of point sources is small and scattering is unimportant, our implementation can alternatively treat each source exactly in angular space, producing shadows whose sharpness is only limited by the grid resolution. A third hybrid alternative is to treat only a small number of the locally most luminous point sources explicitly, with the rest of the radiation intensity followed in a radiative diffusion approximation. We have implemented the method in the moving-mesh code AREPO, where it is coupled to the hydrodynamics in an operator-splitting approach that subcycles the radiative transfer alternately with the hydrodynamical evolution steps. We also discuss our treatment of basic photon sink processes relevant to cosmological reionization, with a chemical network that can
Accurate and transferable extended Hückel-type tight-binding parameters
NASA Astrophysics Data System (ADS)
Cerdá, J.; Soria, F.
2000-03-01
We show how the simple extended Hückel theory can be easily parametrized in order to yield accurate band structures for bulk materials, while the resulting optimized atomic orbital basis sets present good transferability properties. The number of parameters involved is exceedingly small, typically ten or eleven per structural phase. We apply the method to almost fifty elemental and compound bulk phases.
NASA Astrophysics Data System (ADS)
Kopparla, P.; Natraj, V.; Spurr, R. J. D.; Shia, R. L.; Yung, Y. L.
2014-12-01
Radiative transfer (RT) computations are an essential component of energy budget calculations in climate models. However, full treatment of RT processes is computationally expensive, prompting usage of 2-stream approximations in operational climate models. This simplification introduces errors of the order of 10% in the top of the atmosphere (TOA) fluxes [Randles et al., 2013]. Natraj et al. [2005, 2010] and Spurr and Natraj [2013] demonstrated the ability of a technique using principal component analysis (PCA) to speed up RT simulations. In the PCA method for RT performance enhancement, empirical orthogonal functions are developed for binned sets of inherent optical properties that possess some redundancy; costly multiple-scattering RT calculations are only done for those (few) optical states corresponding to the most important principal components, and correction factors are applied to approximate radiation fields. Here, we extend the PCA method to a broadband spectral region from the ultraviolet to the shortwave infrared (0.3-3 micron), accounting for major gas absorptions in this region. Comparisons between the new model, called Universal Principal Component Analysis model for Radiative Transfer (UPCART), 2-stream models (such as those used in climate applications) and line-by-line RT models are performed, in order for spectral radiances, spectral fluxes and broadband fluxes. Each of these are calculated at the TOA for several scenarios with varying aerosol types, extinction and scattering optical depth profiles, and solar and viewing geometries. We demonstrate that very accurate radiative forcing estimates can be obtained, with better than 1% accuracy in all spectral regions and better than 0.1% in most cases as compared to an exact line-by-line RT model. The model is comparable in speeds to 2-stream models, potentially rendering UPCART useful for operational General Circulation Models (GCMs). The operational speed and accuracy of UPCART can be further
NASA Astrophysics Data System (ADS)
Kopparla, P.; Natraj, V.; Shia, R. L.; Spurr, R. J. D.; Crisp, D.; Yung, Y. L.
2015-12-01
Radiative transfer (RT) computations form the engine of atmospheric retrieval codes. However, full treatment of RT processes is computationally expensive, prompting usage of two-stream approximations in current exoplanetary atmospheric retrieval codes [Line et al., 2013]. Natraj et al. [2005, 2010] and Spurr and Natraj [2013] demonstrated the ability of a technique using principal component analysis (PCA) to speed up RT computations. In the PCA method for RT performance enhancement, empirical orthogonal functions are developed for binned sets of inherent optical properties that possess some redundancy; costly multiple-scattering RT calculations are only done for those few optical states corresponding to the most important principal components, and correction factors are applied to approximate radiation fields. Kopparla et al. [2015, in preparation] extended the PCA method to a broadband spectral region from the ultraviolet to the shortwave infrared (0.3-3 micron), accounting for major gas absorptions in this region. Here, we apply the PCA method to a some typical (exo-)planetary retrieval problems. Comparisons between the new model, called Universal Principal Component Analysis Radiative Transfer (UPCART) model, two-stream models and line-by-line RT models are performed, for spectral radiances, spectral fluxes and broadband fluxes. Each of these are calculated at the top of the atmosphere for several scenarios with varying aerosol types, extinction and scattering optical depth profiles, and stellar and viewing geometries. We demonstrate that very accurate radiance and flux estimates can be obtained, with better than 1% accuracy in all spectral regions and better than 0.1% in most cases, as compared to a numerically exact line-by-line RT model. The accuracy is enhanced when the results are convolved to typical instrument resolutions. The operational speed and accuracy of UPCART can be further improved by optimizing binning schemes and parallelizing the codes, work
Fast and accurate Coulomb calculation with Gaussian functions.
Füsti-Molnár, László; Kong, Jing
2005-02-15
Coulomb interaction is one of the major time-consuming components in a density functional theory (DFT) calculation. In the last decade, dramatic progresses have been made to improve the efficiency of Coulomb calculation, including continuous fast multipole method (CFMM) and J-engine method, all developed first inside Q-Chem. The most recent development is the advent of Fourier transform Coulomb method developed by Fusti-Molnar and Pulay, and an improved version of the method has been recently implemented in Q-Chem. It replaces the least efficient part of the previous Coulomb methods with an accurate numerical integration scheme that scales in O(N2) instead of O(N4) with the basis size. The result is a much smaller slope in the linear scaling with respect to the molecular size and we will demonstrate through a series of benchmark calculations that it speeds up the calculation of Coulomb energy by several folds over the efficient existing code, i.e., the combination of CFMM and J-engine, without loss of accuracy. Furthermore, we will show that it is complementary to the latter and together the three methods offer the best performance for Coulomb part of DFT calculations, making the DFT calculations affordable for very large systems involving thousands of basis functions. PMID:15743222
Transfer function characteristics of super resolving systems
NASA Technical Reports Server (NTRS)
Milster, Tom D.; Curtis, Craig H.
1992-01-01
Signal quality in an optical storage device greatly depends on the optical system transfer function used to write and read data patterns. The problem is similar to analysis of scanning optical microscopes. Hopkins and Braat have analyzed write-once-read-many (WORM) optical data storage devices. Herein, transfer function analysis of magnetooptic (MO) data storage devices is discussed with respect to improving transfer-function characteristics. Several authors have described improving the transfer function as super resolution. However, none have thoroughly analyzed the MO optical system and effects of the medium. Both the optical system transfer function and effects of the medium of this development are discussed.
Accurate ionization potential of semiconductors from efficient density functional calculations
NASA Astrophysics Data System (ADS)
Ye, Lin-Hui
2016-07-01
Despite its huge successes in total-energy-related applications, the Kohn-Sham scheme of density functional theory cannot get reliable single-particle excitation energies for solids. In particular, it has not been able to calculate the ionization potential (IP), one of the most important material parameters, for semiconductors. We illustrate that an approximate exact-exchange optimized effective potential (EXX-OEP), the Becke-Johnson exchange, can be used to largely solve this long-standing problem. For a group of 17 semiconductors, we have obtained the IPs to an accuracy similar to that of the much more sophisticated G W approximation (GWA), with the computational cost of only local-density approximation/generalized gradient approximation. The EXX-OEP, therefore, is likely as useful for solids as for finite systems. For solid surfaces, the asymptotic behavior of the vx c has effects similar to those of finite systems which, when neglected, typically cause the semiconductor IPs to be underestimated. This may partially explain why standard GWA systematically underestimates the IPs and why using the same GWA procedures has not been able to get an accurate IP and band gap at the same time.
GORRAM: Introducing accurate operational-speed radiative transfer Monte Carlo solvers
NASA Astrophysics Data System (ADS)
Buras-Schnell, Robert; Schnell, Franziska; Buras, Allan
2016-06-01
We present a new approach for solving the radiative transfer equation in horizontally homogeneous atmospheres. The motivation was to develop a fast yet accurate radiative transfer solver to be used in operational retrieval algorithms for next generation meteorological satellites. The core component is the program GORRAM (Generator Of Really Rapid Accurate Monte-Carlo) which generates solvers individually optimized for the intended task. These solvers consist of a Monte Carlo model capable of path recycling and a representative set of photon paths. Latter is generated using the simulated annealing technique. GORRAM automatically takes advantage of limitations on the variability of the atmosphere. Due to this optimization the number of photon paths necessary for accurate results can be reduced by several orders of magnitude. For the shown example of a forward model intended for an aerosol satellite retrieval, comparison with an exact yet slow solver shows that a precision of better than 1% can be achieved with only 36 photons. The computational time is at least an order of magnitude faster than any other type of radiative transfer solver. Merely the lookup table approach often used in satellite retrieval is faster, but on the other hand suffers from limited accuracy. This makes GORRAM-generated solvers an eligible candidate as forward model in operational-speed retrieval algorithms and data assimilation applications. GORRAM also has the potential to create fast solvers of other integrable equations.
Community Colleges and the Transfer Function.
ERIC Educational Resources Information Center
Perkins, Mary E.
This paper examines how the traditional transfer role of the community college has become less significant as a vocational and community-based role has assumed importance. The paper describes factors contributing to the transfer function's decline and illustrates various attitudes surrounding the issue. The history of transfer education is…
VALIDATION OF BENEFIT-TRANSFER FUNCTIONS
1. Identification of benefit-transfer functions that are the most credible. 2. Identification of benefit-transfer issues that are related to transfer method and those related to data limitations. 3. Clarification of issues t...
Wallace, W C; Ghafur, O; Khurmi, C; Sainadh U, Satya; Calvert, J E; Laban, D E; Pullen, M G; Bartschat, K; Grum-Grzhimailo, A N; Wells, D; Quiney, H M; Tong, X M; Litvinyuk, I V; Sang, R T; Kielpinski, D
2016-07-29
Ionization of atoms and molecules in strong laser fields is a fundamental process in many fields of research, especially in the emerging field of attosecond science. So far, demonstrably accurate data have only been acquired for atomic hydrogen (H), a species that is accessible to few investigators. Here, we present measurements of the ionization yield for argon, krypton, and xenon with percent-level accuracy, calibrated using H, in a laser regime widely used in attosecond science. We derive a transferable calibration standard for laser peak intensity, accurate to 1.3%, that is based on a simple reference curve. In addition, our measurements provide a much needed benchmark for testing models of ionization in noble-gas atoms, such as the widely employed single-active electron approximation. PMID:27517769
NASA Astrophysics Data System (ADS)
Wallace, W. C.; Ghafur, O.; Khurmi, C.; Sainadh U, Satya; Calvert, J. E.; Laban, D. E.; Pullen, M. G.; Bartschat, K.; Grum-Grzhimailo, A. N.; Wells, D.; Quiney, H. M.; Tong, X. M.; Litvinyuk, I. V.; Sang, R. T.; Kielpinski, D.
2016-07-01
Ionization of atoms and molecules in strong laser fields is a fundamental process in many fields of research, especially in the emerging field of attosecond science. So far, demonstrably accurate data have only been acquired for atomic hydrogen (H), a species that is accessible to few investigators. Here, we present measurements of the ionization yield for argon, krypton, and xenon with percent-level accuracy, calibrated using H, in a laser regime widely used in attosecond science. We derive a transferable calibration standard for laser peak intensity, accurate to 1.3%, that is based on a simple reference curve. In addition, our measurements provide a much needed benchmark for testing models of ionization in noble-gas atoms, such as the widely employed single-active electron approximation.
NASA Astrophysics Data System (ADS)
Sabatino, D. R.; Praisner, T. J.; Smith, C. R.
1998-11-01
The color change of thermochromic liquid crystals with temperature can be effectively utilized as full-field surface temperature sensors to investigate the fundamental structure of wall turbulence. In order to accurately quantify turbulent heat transfer behavior, a new technique has been developed for the calibration of wide-band micro-encapsulated thermochromic liquid crystals. Lighting/viewing arrangements are described and evaluated for ease of implementation and accuracy of the displayed color. This new technique employs images recorded in-situ with the test surface systematically exposed to a series of uniform temperature conditions spanning the bandwidth of the liquid crystals. This sequence of images is used to generate point-wise color/temperature calibration curves for the entire surface. Experimental results will be presented illustrating the application of the technique for assessment of spatial/temporal surface heat transfer behavior due to selected turbulent flows in a water channel
Exponentially accurate approximations to piece-wise smooth periodic functions
NASA Technical Reports Server (NTRS)
Greer, James; Banerjee, Saheb
1995-01-01
A family of simple, periodic basis functions with 'built-in' discontinuities are introduced, and their properties are analyzed and discussed. Some of their potential usefulness is illustrated in conjunction with the Fourier series representations of functions with discontinuities. In particular, it is demonstrated how they can be used to construct a sequence of approximations which converges exponentially in the maximum norm to a piece-wise smooth function. The theory is illustrated with several examples and the results are discussed in the context of other sequences of functions which can be used to approximate discontinuous functions.
Accurate Time/Frequency Transfer Method Using Bi-Directional WDM Transmission
NASA Technical Reports Server (NTRS)
Imaoka, Atsushi; Kihara, Masami
1996-01-01
An accurate time transfer method is proposed using b-directional wavelength division multiplexing (WDM) signal transmission along a single optical fiber. This method will be used in digital telecommunication networks and yield a time synchronization accuracy of better than 1 ns for long transmission lines over several tens of kilometers. The method can accurately measure the difference in delay between two wavelength signals caused by the chromatic dispersion of the fiber in conventional simple bi-directional dual-wavelength frequency transfer methods. We describe the characteristics of this difference in delay and then show that the accuracy of the delay measurements can be obtained below 0.1 ns by transmitting 156 Mb/s times reference signals of 1.31 micrometer and 1.55 micrometers along a 50 km fiber using the proposed method. The sub-nanosecond delay measurement using the simple bi-directional dual-wavelength transmission along a 100 km fiber with a wavelength spacing of 1 nm in the 1.55 micrometer range is also shown.
Development of highly accurate approximate scheme for computing the charge transfer integral.
Pershin, Anton; Szalay, Péter G
2015-08-21
The charge transfer integral is a key parameter required by various theoretical models to describe charge transport properties, e.g., in organic semiconductors. The accuracy of this important property depends on several factors, which include the level of electronic structure theory and internal simplifications of the applied formalism. The goal of this paper is to identify the performance of various approximate approaches of the latter category, while using the high level equation-of-motion coupled cluster theory for the electronic structure. The calculations have been performed on the ethylene dimer as one of the simplest model systems. By studying different spatial perturbations, it was shown that while both energy split in dimer and fragment charge difference methods are equivalent with the exact formulation for symmetrical displacements, they are less efficient when describing transfer integral along the asymmetric alteration coordinate. Since the "exact" scheme was found computationally expensive, we examine the possibility to obtain the asymmetric fluctuation of the transfer integral by a Taylor expansion along the coordinate space. By exploring the efficiency of this novel approach, we show that the Taylor expansion scheme represents an attractive alternative to the "exact" calculations due to a substantial reduction of computational costs, when a considerably large region of the potential energy surface is of interest. Moreover, we show that the Taylor expansion scheme, irrespective of the dimer symmetry, is very accurate for the entire range of geometry fluctuations that cover the space the molecule accesses at room temperature. PMID:26298117
Development of highly accurate approximate scheme for computing the charge transfer integral
Pershin, Anton; Szalay, Péter G.
2015-08-21
The charge transfer integral is a key parameter required by various theoretical models to describe charge transport properties, e.g., in organic semiconductors. The accuracy of this important property depends on several factors, which include the level of electronic structure theory and internal simplifications of the applied formalism. The goal of this paper is to identify the performance of various approximate approaches of the latter category, while using the high level equation-of-motion coupled cluster theory for the electronic structure. The calculations have been performed on the ethylene dimer as one of the simplest model systems. By studying different spatial perturbations, it was shown that while both energy split in dimer and fragment charge difference methods are equivalent with the exact formulation for symmetrical displacements, they are less efficient when describing transfer integral along the asymmetric alteration coordinate. Since the “exact” scheme was found computationally expensive, we examine the possibility to obtain the asymmetric fluctuation of the transfer integral by a Taylor expansion along the coordinate space. By exploring the efficiency of this novel approach, we show that the Taylor expansion scheme represents an attractive alternative to the “exact” calculations due to a substantial reduction of computational costs, when a considerably large region of the potential energy surface is of interest. Moreover, we show that the Taylor expansion scheme, irrespective of the dimer symmetry, is very accurate for the entire range of geometry fluctuations that cover the space the molecule accesses at room temperature.
Wiener filter estimation of transfer functions.
Kessel, Robert
2004-01-01
The use of a Wiener filter estimate for the linear transfer function can significantly improve the description of behavioral dynamics. This report presents a two-pass, Monte-Carlo-based algorithm that is well suited to repeated-trials local average measurements. The Wiener filter transfer functions strongly suppress noise artifacts as well as allow reliable transfer function determination under a much wider class of reinforcement schedules. Implications of expanding the possible form of experimental design are considered along with improvements in the fidelity of resulting predictions. PMID:15357511
Application of transfer functions to canned tuna fish thermal processing.
Ansorena, M R; del Valle, C; Salvadori, V O
2010-02-01
Design and optimization of thermal processing of foods need accurate dynamic models to ensure safe and high quality food products. Transfer functions had been demonstrated to be a useful tool to predict thermal histories, especially under variable operating conditions. This work presents the development and experimental validation of a dynamic model (discrete transfer function) for the thermal processing of tuna fish in steam retorts. Transfer function coefficients were obtained numerically, using commercial software of finite elements (COMSOL Multiphysics) to solve the heat transfer balance. Dependence of transfer function coefficients on the characteristic dimensions of cylindrical containers (diameter and height) and on the sampling interval is reported. A simple equation, with two empirical parameters that depends on the container dimensions, represented the behavior of transfer function coefficients with very high accuracy. Experimental runs with different size containers and different external conditions (constant and variable retort temperature) were carried out to validate the developed methodology. Performance of the thermal process simulation was tested for predicting internal product temperature of the cold point and lethality and very satisfactory results were found. The developed methodology can play an important role in reducing the computational effort while guaranteeing accuracy by simplifying the calculus involved in the solution of heat balances with variable external conditions and emerges as a potential approach to the implementation of new food control strategies leading not only to more efficient processes but also to product quality and safety. PMID:21339120
Accurate estimators of correlation functions in Fourier space
NASA Astrophysics Data System (ADS)
Sefusatti, E.; Crocce, M.; Scoccimarro, R.; Couchman, H. M. P.
2016-08-01
Efficient estimators of Fourier-space statistics for large number of objects rely on fast Fourier transforms (FFTs), which are affected by aliasing from unresolved small-scale modes due to the finite FFT grid. Aliasing takes the form of a sum over images, each of them corresponding to the Fourier content displaced by increasing multiples of the sampling frequency of the grid. These spurious contributions limit the accuracy in the estimation of Fourier-space statistics, and are typically ameliorated by simultaneously increasing grid size and discarding high-frequency modes. This results in inefficient estimates for e.g. the power spectrum when desired systematic biases are well under per cent level. We show that using interlaced grids removes odd images, which include the dominant contribution to aliasing. In addition, we discuss the choice of interpolation kernel used to define density perturbations on the FFT grid and demonstrate that using higher order interpolation kernels than the standard Cloud-In-Cell algorithm results in significant reduction of the remaining images. We show that combining fourth-order interpolation with interlacing gives very accurate Fourier amplitudes and phases of density perturbations. This results in power spectrum and bispectrum estimates that have systematic biases below 0.01 per cent all the way to the Nyquist frequency of the grid, thus maximizing the use of unbiased Fourier coefficients for a given grid size and greatly reducing systematics for applications to large cosmological data sets.
An Accurate Density Functional from Exchange-Correlation Hole
NASA Astrophysics Data System (ADS)
Tao, Jianmin; Mo, Yuxiang
The exchange-correlation hole is most fundamentally important in the development and understanding of density functional theory (DFT). However, due to the nonlocal nature of the exchange-correlation hole, development of DFT from the underlying hole presents a great challenge, and the works along this direction are limited. Here I will discuss a novel nonempirical DFT based on a semilocal hole, which is obtained from the density matrix expansion. Extensive tests on molecules and solids show that this functional can achieve remarkable accuracy for wide-ranging properties in condensed matter physics and quantum chemistry. This work was supported by NSF under Grant No. CHE-1261918.
Nerve Transfers to Restore Elbow Function.
Bulstra, Liselotte F; Shin, Alexander Y
2016-05-01
The purpose of this article is to provide an overview of the various nerve transfer options for restoration of elbow function. This article describes nerve transfer strategies for elbow flexion and extension including the indications, limitations, and expected outcomes based on current literature. PMID:27094889
Accurate and fast DFT calculations with the AM05 functional
NASA Astrophysics Data System (ADS)
Mattsson, Ann E.
2008-03-01
The AM05 functional [1] has the same excellent performance for solids as the hybrid density functionals tested in Paier et. al. (J. Chem. Phys 124, 154709 (2006); ibid 125, 249901 (2006)). This confirms the original finding that AM05 performs exceptionally well for solids and surfaces. While hybrid functionals are computationally expensive, preveting them from being used in large systems and/or long molecular dynamics simulations, the AM05 functional is on a regular semi-local GGA form with corresponding computational cost. The performance of AM05 is even superior to an `informed choice' between LDA and PBE. By comparing data from different electronic-structure codes we have determined that the numerical errors in this study are equal to or smaller than corresponding experimental uncertainties. Results for other systems will also be presented. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. [1] R. Armiento and A. E. Mattsson, Phys. Rev. B 72, 085108 (2005).
A fast and accurate PCA based radiative transfer model: Extension to the broadband shortwave region
NASA Astrophysics Data System (ADS)
Kopparla, Pushkar; Natraj, Vijay; Spurr, Robert; Shia, Run-Lie; Crisp, David; Yung, Yuk L.
2016-04-01
Accurate radiative transfer (RT) calculations are necessary for many earth-atmosphere applications, from remote sensing retrieval to climate modeling. A Principal Component Analysis (PCA)-based spectral binning method has been shown to provide an order of magnitude increase in computational speed while maintaining an overall accuracy of 0.01% (compared to line-by-line calculations) over narrow spectral bands. In this paper, we have extended the PCA method for RT calculations over the entire shortwave region of the spectrum from 0.3 to 3 microns. The region is divided into 33 spectral fields covering all major gas absorption regimes. We find that the RT performance runtimes are shorter by factors between 10 and 100, while root mean square errors are of order 0.01%.
Transfer Function Control for Biometric Monitoring System
NASA Technical Reports Server (NTRS)
Chmiel, Alan J. (Inventor); Humphreys, Bradley T. (Inventor); Grodinsky, Carlos M. (Inventor)
2015-01-01
A modular apparatus for acquiring biometric data may include circuitry operative to receive an input signal indicative of a biometric condition, the circuitry being configured to process the input signal according to a transfer function thereof and to provide a corresponding processed input signal. A controller is configured to provide at least one control signal to the circuitry to programmatically modify the transfer function of the modular system to facilitate acquisition of the biometric data.
Nerve Transfers to Restore Shoulder Function.
Leechavengvongs, Somsak; Malungpaishorpe, Kanchai; Uerpairojkit, Chairoj; Ng, Chye Yew; Witoonchart, Kiat
2016-05-01
The restoration of shoulder function after brachial plexus injury represents a significant challenge facing the peripheral nerve surgeons. This is owing to a combination of the complex biomechanics of the shoulder girdle, the multitude of muscles and nerves that could be potentially injured, and a limited number of donor options. In general, nerve transfer is favored over tendon transfer, because the biomechanics of the musculotendinous units are not altered. This article summarizes the surgical techniques and clinical results of nerve transfers for restoration of shoulder function. PMID:27094888
Ren, Yinghui; Bian, Wensheng
2015-05-21
We present the first accurate quantum dynamics calculations of mode-specific tunneling splittings in a sequential double-hydrogen transfer process. This is achieved in the vinylidene-acetylene system, the simplest molecular system of this kind, and by large-scale parallel computations with an efficient theoretical scheme developed by us. In our scheme, basis functions are customized for the hydrogen transfer process; a 4-dimensional basis contraction strategy is combined with the preconditioned inexact spectral transform method; efficient parallel implementation is achieved. Mode-specific permutation tunneling splittings of vinylidene states are reported and tremendous mode-specific promotion effects are revealed; in particular, the CH2 rock mode enhances the ground-state splitting by a factor of 10(3). We find that the ground-state vinylidene has a reversible-isomerization time of 622 ps, much longer than all previous estimates. Our calculations also shed light on the importance of the deep intermediate well and vibrational excitation in the double-hydrogen transfer processes. PMID:26263255
Free Functional Muscle Transfers to Restore Upper Extremity Function.
Krauss, Emily M; Tung, Thomas H; Moore, Amy M
2016-05-01
Free functional muscle transfer provides an option for functional restoration when nerve reconstruction and tendon transfers are not feasible. To ensure a successful outcome, many factors need to be optimized, including proper patient selection, timing of intervention, donor muscle and motor nerve selection, optimal microneurovascular technique and tension setting, proper postoperative management, and appropriate rehabilitation. Functional outcomes of various applications to the upper extremity and the authors' algorithm for the use of free functional muscle transfer are also included in this article. PMID:27094895
Modulation transfer function for infrared reflectarrays.
Gómez-Pedrero, Jose Antonio; Ginn, James; Alda, Javier; Boreman, Glenn
2011-09-20
The quality of the image produced by optical reflectarrays as a function of the F/#, polarization, and wavelength is analyzed in this paper. The results are expressed as monochromatic and polychromatic modulation transfer functions. They show that large aperture multilevel reflectarrays perform quite close to the diffraction-limited case. The chromatic aberrations make these elements highly wavelength-selective. PMID:21947056
NASA Astrophysics Data System (ADS)
O'Brien, Edward P.; Morrison, Greg; Brooks, Bernard R.; Thirumalai, D.
2009-03-01
Single molecule Förster resonance energy transfer (FRET) experiments are used to infer the properties of the denatured state ensemble (DSE) of proteins. From the measured average FRET efficiency, ⟨E⟩, the distance distribution P(R ) is inferred by assuming that the DSE can be described as a polymer. The single parameter in the appropriate polymer model (Gaussian chain, wormlike chain, or self-avoiding walk) for P(R ) is determined by equating the calculated and measured ⟨E⟩. In order to assess the accuracy of this "standard procedure," we consider the generalized Rouse model (GRM), whose properties [⟨E⟩ and P(R )] can be analytically computed, and the Molecular Transfer Model for protein L for which accurate simulations can be carried out as a function of guanadinium hydrochloride (GdmCl) concentration. Using the precisely computed ⟨E⟩ for the GRM and protein L, we infer P(R ) using the standard procedure. We find that the mean end-to-end distance can be accurately inferred (less than 10% relative error) using ⟨E⟩ and polymer models for P(R ). However, the value extracted for the radius of gyration (Rg) and the persistence length (lp) are less accurate. For protein L, the errors in the inferred properties increase as the GdmCl concentration increases for all polymer models. The relative error in the inferred Rg and lp, with respect to the exact values, can be as large as 25% at the highest GdmCl concentration. We propose a self-consistency test, requiring measurements of ⟨E⟩ by attaching dyes to different residues in the protein, to assess the validity of describing DSE using the Gaussian model. Application of the self-consistency test to the GRM shows that even for this simple model, which exhibits an order→disorder transition, the Gaussian P(R ) is inadequate. Analysis of experimental data of FRET efficiencies with dyes at several locations for the cold shock protein, and simulations results for protein L, for which accurate FRET
Calculation of retroreflector array transfer functions
NASA Technical Reports Server (NTRS)
Arnold, D. A.
1972-01-01
Computer programs have been developed for calculating the transfer function of a retroreflector array. The transfer functions provide range corrections and effective reflecting areas for the retroreflector arrays carried by satellites now in orbit. This information can be used to estimate laser echo signal strengths and to correct laser range measurements in order to obtain the range to the center of mass of the satellite. The values are tabulated for various angles of incidence of the laser beam with respect to the symmetry axis of the satellite. Transfer functions have been computed for the following satellites: BE-B, BE-C, Geos 1, D1C, D1D, Geos 2, Peole, and Geos C.
Wavelet excited measurement of system transfer function.
Olkkonen, H; Olkkonen, J T
2007-02-01
This article introduces a new method, which is referred to as the wavelet excitation method (WEM), for the measurement of the system transfer function. Instead of commonly used impulse or sine wave excitations, the method uses a sequential excitation by biorthogonal symmetric wavelets. The system transfer function is reconstructed from the output measurements. In the WEM the signals can be designed so that if N different excitation sequences are used and the excitation rate is f, the sampling rate of the analog-to-digital converter can be reduced to f/N. The WEM is especially advantageous in testing systems, where high quality impulse excitation cannot be applied. The WEM gave consistent results in transfer function measurements of various multistage amplifiers with the linear circuit analysis (SPICE) and the sine wave excitation methods. The WEM makes available new high speed sensor applications, where the sampling rate of the sensor may be considerably lower compared with the system bandwidth. PMID:17578145
Instrument transfer function of slope measuring deflectometry systems.
Su, Tianquan; Maldonado, Alejandro; Su, Peng; Burge, James H
2015-04-01
Slope measuring deflectometry (SMD) systems are developing rapidly in testing freeform optics. They measure the surface slope using a camera and an incoherent source. The principle of the test is mainly discussed in geometric optic domain. The system response as a function of spatial frequency or instrument transfer function (ITF) has yet to be studied thoroughly. Through mathematical modeling, simulation, and experiment we show that the ITF of an SMD system is very close to the modulation transfer function of the camera used. Furthermore, the ITF can be enhanced using a deconvolution filter. This study will lead to more accurate measurements in SMD and will show the physical optics nature of these tests. PMID:25967213
Pavanello, Michele; Van Voorhis, Troy; Visscher, Lucas; Neugebauer, Johannes
2013-02-07
Quantum-mechanical methods that are both computationally fast and accurate are not yet available for electronic excitations having charge transfer character. In this work, we present a significant step forward towards this goal for those charge transfer excitations that take place between non-covalently bound molecules. In particular, we present a method that scales linearly with the number of non-covalently bound molecules in the system and is based on a two-pronged approach: The molecular electronic structure of broken-symmetry charge-localized states is obtained with the frozen density embedding formulation of subsystem density-functional theory; subsequently, in a post-SCF calculation, the full-electron Hamiltonian and overlap matrix elements among the charge-localized states are evaluated with an algorithm which takes full advantage of the subsystem DFT density partitioning technique. The method is benchmarked against coupled-cluster calculations and achieves chemical accuracy for the systems considered for intermolecular separations ranging from hydrogen-bond distances to tens of Angstroms. Numerical examples are provided for molecular clusters comprised of up to 56 non-covalently bound molecules.
Enhancements to the SSME transfer function modeling code
NASA Technical Reports Server (NTRS)
Irwin, R. Dennis; Mitchell, Jerrel R.; Bartholomew, David L.; Glenn, Russell D.
1995-01-01
effort to filter out high frequency characteristics. The fourth method removes the presumed system excitation and its harmonics in order to investigate the effects of the excitation on the modeling process. The fifth method is an attempt to apply constrained RID to obtain better transfer functions through more accurate modeling over certain frequency ranges. Section 4 presents some new C main files which were created to round out the functionality of the existing SSME transfer function modeling code. It is now possible to go from time data to transfer function models using only the C codes; it is not necessary to rely on external software. The new C main files and instructions for their use are included. Section 5 presents current and future enhancements to the XPLOT graphics program which was delivered with the initial software. Several new features which have been added to the program are detailed in the first part of this section. The remainder of Section 5 then lists some possible features which may be added in the future. Section 6 contains the conclusion section of this report. Section 6.1 is an overview of the work including a summary and observations relating to finding transfer functions with the SSME code. Section 6.2 contains information relating to future work on the project.
Exploring the transferability of safety performance functions.
Farid, Ahmed; Abdel-Aty, Mohamed; Lee, Jaeyoung; Eluru, Naveen; Wang, Jung-Han
2016-09-01
Safety performance functions (SPFs), by predicting the number of crashes on roadway facilities, have been a vital tool in the highway safety area. The SPFs are typically applied for identifying hot spots in network screening and evaluating the effectiveness of road safety countermeasures. The Highway Safety Manual (HSM) provides a series of SPFs for several crash types by various roadway facilities. The SPFs, provided in the HSM, were developed using data from multiple states. In regions without local jurisdiction based SPFs it is common practice to adopt national SPFs for crash prediction. There has been little research to examine the viability of such national level models for local jurisdictions. Towards understanding the influence of SPF transferability, we examine the rural divided multilane highway models from Florida, Ohio, and California. Traffic, roadway geometry and crash data from the three states are employed to estimate single-state SPFs, two-state SPFs and three-state SPFs. The SPFs are estimated using the negative binomial model formulation for several crash types and severities. To evaluate transferability of models, we estimate a transfer index that allows us to understand which models transfer adequately to other regions. The results indicate that models from Florida and California seem to be more transferable compared to models from Ohio. More importantly, we observe that the transfer index increases when we used pooled data (from two or three states). Finally, to assist in model transferability, we propose a Modified Empirical Bayes (MEB) measure that provides segment specific calibration factors for transferring SPFs to local jurisdictions. The proposed measure is shown to outperform the HSM calibration factor for transferring SPFs. PMID:27322637
Energy Transfer and a Recurring Mathematical Function
ERIC Educational Resources Information Center
Atkin, Keith
2013-01-01
This paper extends the interesting work of a previous contributor concerning the analogies between physical phenomena such as mechanical collisions and the transfer of power in an electric circuit. Emphasis is placed on a mathematical function linking these different areas of physics. This unifying principle is seen as an exciting opportunity to…
NASA Astrophysics Data System (ADS)
Guerlet, Sandrine; Spiga, A.; Sylvestre, M.; Fouchet, T.; Millour, E.; Wordsworth, R.; Leconte, J.; Forget, F.
2013-10-01
Recent observations of Saturn’s stratospheric thermal structure and composition revealed new phenomena: an equatorial oscillation in temperature, reminiscent of the Earth's Quasi-Biennal Oscillation ; strong meridional contrasts of hydrocarbons ; a warm “beacon” associated with the powerful 2010 storm. Those signatures cannot be reproduced by 1D photochemical and radiative models and suggest that atmospheric dynamics plays a key role. This motivated us to develop a complete 3D General Circulation Model (GCM) for Saturn, based on the LMDz hydrodynamical core, to explore the circulation, seasonal variability, and wave activity in Saturn's atmosphere. In order to closely reproduce Saturn's radiative forcing, a particular emphasis was put in obtaining fast and accurate radiative transfer calculations. Our radiative model uses correlated-k distributions and spectral discretization tailored for Saturn's atmosphere. We include internal heat flux, ring shadowing and aerosols. We will report on the sensitivity of the model to spectral discretization, spectroscopic databases, and aerosol scenarios (varying particle sizes, opacities and vertical structures). We will also discuss the radiative effect of the ring shadowing on Saturn's atmosphere. We will present a comparison of temperature fields obtained with this new radiative equilibrium model to that inferred from Cassini/CIRS observations. In the troposphere, our model reproduces the observed temperature knee caused by heating at the top of the tropospheric aerosol layer. In the lower stratosphere (20mbar
Transfer function bounds on the performance of turbo codes
NASA Technical Reports Server (NTRS)
Divsalar, D.; Dolinar, S.; Pollara, F.; Mceliece, R. J.
1995-01-01
In this article we apply transfer function bounding techniques to obtain upper bounds on the bit-error rate for maximum likelihood decoding of turbo codes constructed with random permutations. These techniques are applied to two turbo codes with constraint length 3 and later extended to other codes. The performance predicted by these bounds is compared with simulation results. The bounds are useful in estimating the 'error floor' that is difficult to measure by simulation, and they provide insight on how to lower this floor. More refined bounds are needed for accurate performance measures at lower signal-to-noise ratios.
Measuring Dynamic Transfer Functions of Cavitating Pumps
NASA Technical Reports Server (NTRS)
Baun, Daniel
2007-01-01
A water-flow test facility has been built to enable measurement of dynamic transfer functions (DTFs) of cavitating pumps and of inducers in such pumps. Originally, the facility was intended for use in an investigation of the effects of cavitation in a rocket-engine low-pressure oxygen turbopump. The facility can also be used to measure DTFs of cavitating pumps in general
Filtering Non-Linear Transfer Functions on Surfaces.
Heitz, Eric; Nowrouzezahrai, Derek; Poulin, Pierre; Neyret, Fabrice
2014-07-01
Applying non-linear transfer functions and look-up tables to procedural functions (such as noise), surface attributes, or even surface geometry are common strategies used to enhance visual detail. Their simplicity and ability to mimic a wide range of realistic appearances have led to their adoption in many rendering problems. As with any textured or geometric detail, proper filtering is needed to reduce aliasing when viewed across a range of distances, but accurate and efficient transfer function filtering remains an open problem for several reasons: transfer functions are complex and non-linear, especially when mapped through procedural noise and/or geometry-dependent functions, and the effects of perspective and masking further complicate the filtering over a pixel's footprint. We accurately solve this problem by computing and sampling from specialized filtering distributions on the fly, yielding very fast performance. We investigate the case where the transfer function to filter is a color map applied to (macroscale) surface textures (like noise), as well as color maps applied according to (microscale) geometric details. We introduce a novel representation of a (potentially modulated) color map's distribution over pixel footprints using Gaussian statistics and, in the more complex case of high-resolution color mapped microsurface details, our filtering is view- and light-dependent, and capable of correctly handling masking and occlusion effects. Our approach can be generalized to filter other physical-based rendering quantities. We propose an application to shading with irradiance environment maps over large terrains. Our framework is also compatible with the case of transfer functions used to warp surface geometry, as long as the transformations can be represented with Gaussian statistics, leading to proper view- and light-dependent filtering results. Our results match ground truth and our solution is well suited to real-time applications, requires only a few
NASA Astrophysics Data System (ADS)
Sun, Yuansheng; Periasamy, Ammasi
2010-03-01
Förster resonance energy transfer (FRET) microscopy is commonly used to monitor protein interactions with filter-based imaging systems, which require spectral bleedthrough (or cross talk) correction to accurately measure energy transfer efficiency (E). The double-label (donor+acceptor) specimen is excited with the donor wavelength, the acceptor emission provided the uncorrected FRET signal and the donor emission (the donor channel) represents the quenched donor (qD), the basis for the E calculation. Our results indicate this is not the most accurate determination of the quenched donor signal as it fails to consider the donor spectral bleedthrough (DSBT) signals in the qD for the E calculation, which our new model addresses, leading to a more accurate E result. This refinement improves E comparisons made with lifetime and spectral FRET imaging microscopy as shown here using several genetic (FRET standard) constructs, where cerulean and venus fluorescent proteins are tethered by different amino acid linkers.
Aerosol modulation transfer function: an overview
NASA Astrophysics Data System (ADS)
Kopeika, Norman S.
1997-09-01
The aerosol modulation transfer function (MTF) describes blurring deriving from light scatter caused by aerosols. Little scintillations or image dancing are involved. When overall atmospheric point spread function (PSF) is analyzed for its turbulence component deriving from angle-of-arrival fluctuations or scintillations, a significant portion of the PSF is left over. This is the aerosol component. This overview describes the basic physical mechanisms for aerosol MTF and its wavelength, weather, and time exposure dependences, as well as a comparison to turbulence MiT.
Contextual Control by Function and Form of Transfer of Functions
ERIC Educational Resources Information Center
Perkins, David R.; Dougher, Michael J.; Greenway, David E.
2007-01-01
This study investigated conditions leading to contextual control by stimulus topography over transfer of functions. Three 4-member stimulus equivalence classes, each consisting of four (A, B, C, D) topographically distinct visual stimuli, were established for 5 college students. Across classes, designated A stimuli were open-ended linear figures,…
Multiple functions of microsomal triglyceride transfer protein
2012-01-01
Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles. Its role as an essential chaperone for the biosynthesis of apolipoprotein B (apoB)-containing triglyceride-rich lipoproteins was established after the realization that abetalipoproteinemia patients carry mutations in the MTTP gene resulting in the loss of its lipid transfer activity. Now it is known that it also plays a role in the biosynthesis of CD1, glycolipid presenting molecules, as well as in the regulation of cholesterol ester biosynthesis. In this review, we will provide a historical perspective about the identification, purification and characterization of MTP, describe methods used to measure its lipid transfer activity, and discuss tissue expression and function. Finally, we will review the role MTP plays in the assembly of apoB-lipoprotein, the regulation of cholesterol ester synthesis, biosynthesis of CD1 proteins and propagation of hepatitis C virus. We will also provide a brief overview about the clinical potentials of MTP inhibition. PMID:22353470
Accurate definition of brain regions position through the functional landmark approach.
Thirion, Bertrand; Varoquaux, Gaël; Poline, Jean-Baptiste
2010-01-01
In many application of functional Magnetic Resonance Imaging (fMRI), including clinical or pharmacological studies, the definition of the location of the functional activity between subjects is crucial. While current acquisition and normalization procedures improve the accuracy of the functional signal localization, it is also important to ensure that functional foci detection yields accurate results, and reflects between-subject variability. Here we introduce a fast functional landmark detection procedure, that explicitly models the spatial variability of activation foci in the observed population. We compare this detection approach to standard statistical maps peak extraction procedures: we show that it yields more accurate results on simulations, and more reproducible results on a large cohort of subjects. These results demonstrate that explicit functional landmark modeling approaches are more effective than standard statistical mapping for brain functional focus detection. PMID:20879321
Accurate Semilocal Density Functional for Condensed-Matter Physics and Quantum Chemistry.
Tao, Jianmin; Mo, Yuxiang
2016-08-12
Most density functionals have been developed by imposing the known exact constraints on the exchange-correlation energy, or by a fit to a set of properties of selected systems, or by both. However, accurate modeling of the conventional exchange hole presents a great challenge, due to the delocalization of the hole. Making use of the property that the hole can be made localized under a general coordinate transformation, here we derive an exchange hole from the density matrix expansion, while the correlation part is obtained by imposing the low-density limit constraint. From the hole, a semilocal exchange-correlation functional is calculated. Our comprehensive test shows that this functional can achieve remarkable accuracy for diverse properties of molecules, solids, and solid surfaces, substantially improving upon the nonempirical functionals proposed in recent years. Accurate semilocal functionals based on their associated holes are physically appealing and practically useful for developing nonlocal functionals. PMID:27563956
Accurate Semilocal Density Functional for Condensed-Matter Physics and Quantum Chemistry
NASA Astrophysics Data System (ADS)
Tao, Jianmin; Mo, Yuxiang
2016-08-01
Most density functionals have been developed by imposing the known exact constraints on the exchange-correlation energy, or by a fit to a set of properties of selected systems, or by both. However, accurate modeling of the conventional exchange hole presents a great challenge, due to the delocalization of the hole. Making use of the property that the hole can be made localized under a general coordinate transformation, here we derive an exchange hole from the density matrix expansion, while the correlation part is obtained by imposing the low-density limit constraint. From the hole, a semilocal exchange-correlation functional is calculated. Our comprehensive test shows that this functional can achieve remarkable accuracy for diverse properties of molecules, solids, and solid surfaces, substantially improving upon the nonempirical functionals proposed in recent years. Accurate semilocal functionals based on their associated holes are physically appealing and practically useful for developing nonlocal functionals.
Accurate FDTD modelling for dispersive media using rational function and particle swarm optimisation
NASA Astrophysics Data System (ADS)
Chung, Haejun; Ha, Sang-Gyu; Choi, Jaehoon; Jung, Kyung-Young
2015-07-01
This article presents an accurate finite-difference time domain (FDTD) dispersive modelling suitable for complex dispersive media. A quadratic complex rational function (QCRF) is used to characterise their dispersive relations. To obtain accurate coefficients of QCRF, in this work, we use an analytical approach and a particle swarm optimisation (PSO) simultaneously. In specific, an analytical approach is used to obtain the QCRF matrix-solving equation and PSO is applied to adjust a weighting function of this equation. Numerical examples are used to illustrate the validity of the proposed FDTD dispersion model.
Partially coherent contrast-transfer-function approximation.
Nesterets, Yakov I; Gureyev, Timur E
2016-04-01
The contrast-transfer-function (CTF) approximation, widely used in various phase-contrast imaging techniques, is revisited. CTF validity conditions are extended to a wide class of strongly absorbing and refracting objects, as well as to nonuniform partially coherent incident illumination. Partially coherent free-space propagators, describing amplitude and phase in-line contrast, are introduced and their properties are investigated. The present results are relevant to the design of imaging experiments with partially coherent sources, as well as to the analysis and interpretation of the corresponding images. PMID:27140752
Pressure Transfer Functions for Interfacial Fluids Problems
NASA Astrophysics Data System (ADS)
Chen, Robin Ming; Hur, Vera Mikyoung; Walsh, Samuel
2016-06-01
We make a consistent derivation, from the governing equations, of the pressure transfer function in the small-amplitude Stokes wave regime and the hydrostatic approximation in the small-amplitude solitary water wave regime, in the presence of a background shear flow. The results agree with the well-known formulae in the zero vorticity case, but they incorporate the effects of vorticity through solutions to the Rayleigh equation. We extend the results to permit continuous density stratification and to internal waves between two constant-density fluids. Several examples are discussed.
Computer method for identification of boiler transfer functions
NASA Technical Reports Server (NTRS)
Miles, J. H.
1972-01-01
Iterative computer aided procedure was developed which provides for identification of boiler transfer functions using frequency response data. Method uses frequency response data to obtain satisfactory transfer function for both high and low vapor exit quality data.
Modulation transfer function of bar code scanning
NASA Astrophysics Data System (ADS)
Tang, Hong; Milster, Tom D.
1998-09-01
Bar code scanners are ubiquitous in supermarkets. As a bar code is passed over a scanner, a laser beam scans across the bar code. The scattered light is modulated by the reflectivity of the bars and spaces of the bar code. The bar code scanning process can be described as a 1D convolution of the scanning laser profile and the bar code reflectivity function. The modulation transfer function (MTF) of bar code scanning is the Fourier transform of the marginal profile of the laser beam. The properties of the MTF of bar code scanning is similar to that of an incoherent imaging system. Measurements of the MTF of bar code scanning at one focus position are presented. The experimental results are then discussed.
More accurate fitting of {sup 125}I and {sup 103}Pd radial dose functions
Taylor, R. E. P.; Rogers, D. W. O.
2008-09-15
In this study an improved functional form for fitting the radial dose functions, g(r), of {sup 125}I and {sup 103}Pd brachytherapy seeds is presented. The new function is capable of accurately fitting radial dose functions over ranges as large as 0.05 cm{<=}r{<=}10 cm for {sup 125}I seeds and 0.10 cm{<=}r{<=}10 cm for {sup 103}Pd seeds. The average discrepancies between fit and calculated data are less than 0.5% over the full range of fit and maximum discrepancies are 2% or less. The fitting function is also capable of accounting for the sharp increase in g(r) (upturn) seen for some sources for r<0.1 cm. This upturn has previously been attributed to the breakdown of the approximation of the sources as a line, however, in this study we demonstrate that another contributing factor is the 4.5 keV characteristic x-rays emitted from the Ti seed casing. Radial dose functions are calculated for 18 {sup 125}I seeds and 9 {sup 103}Pd seeds using the EGSnrc Monte Carlo user-code BrachyDose. Fitting coefficients of the new function are tabulated for all 27 seeds. Extrapolation characteristics of the function are also investigated. The new functional form is an improvement over currently used fitting functions with its main strength being the ability to accurately fit the rapidly varying radial dose function at small distances. The new function is an excellent candidate for fitting the radial dose function of all {sup 103}Pd and {sup 125}I brachytherapy seeds and will increase the accuracy of dose distributions calculated around brachytherapy seeds using the TG-43 protocol over a wider range of data. More accurate values of g(r) for r<0.5 cm may be particularly important in the treatment of ocular melanoma.
Optical design of optical transfer function instrument
NASA Astrophysics Data System (ADS)
Zhang, Liangjun; Chen, Xinhua; Chen, Yuheng; Ji, Yiqun; Xiang, Chunchang; Shen, Weimin
2009-11-01
The optical design of Optical transfer function (OTF) instrument, which is based on the image Fourier analysis method, is presented. To perform infinite conjugate testing of an optical system, the designed system is mainly composed of the object generator, lens under test, and image analyzer. The object generator offers an object at infinite distance with known spectral and spatial content. It includes the illumination system and the collimating system. The illumination system is analyzed and optimized with CODEV and LightTools software. Performance evaluation indicates that its illumination uniformity in the required area is above 95% .The collimation system based on an off-axis parabolic mirror is of the focal length of 2000mm and the entrance pupil diameter 200mm. Through optimization, the image quality of the collimator is excellent and its on-axis modulation transfer function (MTF) approaches diffraction limit. Collimated beam of the target is imaged by the lens under test. The image is magnified and acquired by image analyzer, which is made up of four parts: an infinite conjugate microscope objective, a tube lens, an eyepiece and a CCD camera. Image Results show that this designed scheme meets the requirements of this OTF instrument.
Unbiased rigid registration using transfer functions
NASA Astrophysics Data System (ADS)
Hahn, Dieter A.; Hornegger, Joachim; Bautz, Werner; Kuwert, Torsten; Roemer, Wolfgang
2005-04-01
The evaluation of tumor growth as regression under therapy is an important clinical issue. Rigid registration of sequentially acquired 3D-images has proven its value for this purpose. Existing approaches to rigid image registration use the whole volume for the estimation of the rigid transform. Non-rigid soft tissue deformation, however, will imply a bias to the registration result, because local deformations cannot be modeled by rigid transforms. Anatomical substructures, like bones or teeth, are not affected by these deformations, but follow a rigid transform. This important observation is incorporated in the proposed registration algorithm. The selection of anatomical substructure is done by manual interaction of medical experts adjusting the transfer function of the volume rendering software. The parameters of the transfer function are used to identify the voxels that are considered for registration. A rigid transform is estimated by a quaternion gradient descent algorithm based on the intensity values of the specified tissue classes. Commonly used voxel intensity measures are adjusted to the modified registration algorithm. The contribution describes the mathematical framework of the proposed registration method and its implementation in a commercial software package. The experimental evaluation includes the discussion of different similarity measures, the comparison of the proposed method to established rigid registration techniques and the evaluation of the efficiency of the new method. We conclude with the discussion of potential medical applications of the proposed registration algorithm.
Woods: A fast and accurate functional annotator and classifier of genomic and metagenomic sequences.
Sharma, Ashok K; Gupta, Ankit; Kumar, Sanjiv; Dhakan, Darshan B; Sharma, Vineet K
2015-07-01
Functional annotation of the gigantic metagenomic data is one of the major time-consuming and computationally demanding tasks, which is currently a bottleneck for the efficient analysis. The commonly used homology-based methods to functionally annotate and classify proteins are extremely slow. Therefore, to achieve faster and accurate functional annotation, we have developed an orthology-based functional classifier 'Woods' by using a combination of machine learning and similarity-based approaches. Woods displayed a precision of 98.79% on independent genomic dataset, 96.66% on simulated metagenomic dataset and >97% on two real metagenomic datasets. In addition, it performed >87 times faster than BLAST on the two real metagenomic datasets. Woods can be used as a highly efficient and accurate classifier with high-throughput capability which facilitates its usability on large metagenomic datasets. PMID:25863333
A stable and high-order accurate conjugate heat transfer problem
NASA Astrophysics Data System (ADS)
Lindström, Jens; Nordström, Jan
2010-08-01
This paper analyzes well-posedness and stability of a conjugate heat transfer problem in one space dimension. We study a model problem for heat transfer between a fluid and a solid. The energy method is used to derive boundary and interface conditions that make the continuous problem well-posed and the semi-discrete problem stable. The numerical scheme is implemented using 2nd-, 3rd- and 4th-order finite difference operators on Summation-By-Parts (SBP) form. The boundary and interface conditions are implemented weakly. We investigate the spectrum of the spatial discretization to determine which type of coupling that gives attractive convergence properties. The rate of convergence is verified using the method of manufactured solutions.
Modeling individual differences in ferret external ear transfer functions
NASA Astrophysics Data System (ADS)
Schnupp, Jan W. H.; Booth, John; King, Andrew J.
2003-04-01
Individual variations in head and outer ear size, as well as growth of these structures during development, can markedly alter the values of the binaural and monaural cues which form the basis for auditory localization. This study investigated individual differences in the directional component of the head-related transfer function of both adult and juvenile ferrets. In line with previous studies in humans and cats, intersubject spectral differences were found to be reduced by scaling one of the directional transfer functions on a log-frequency axis. The optimal scale factor correlated most highly with pinna cavity height. Optimal frequency scaling reduced interear spectral difference equally well for adult-juvenile comparisons as for comparisons between pairs of adult ears. This illustrates that the developmental changes in localization cue values should be at least partly predictable on the basis of the expected growth rate of the outer ear structures. Predictions of interaural time differences (ITDs) were also derived from the physical dimensions of the head. ITDs were found to be poorly fitted by the spherical head model, while much better predictions could be derived from a model based on von Mises spherical basis functions. Together, these findings show how more accurate estimates of spatial cue values can be made from knowledge of the dimensions of the head and outer ears, and may facilitate the generation of virtual acoustic space stimuli in the absence of acoustical measurements from individual subjects.
NASA Astrophysics Data System (ADS)
Skone, Jonathan; Govoni, Marco; Galli, Giulia
Dielectric-dependent hybrid [DDH] functionals have recently been shown to yield highly accurate energy gaps and dielectric constants for a wide variety of solids, at a computational cost considerably less than standard GW calculations. The fraction of exact exchange included in the definition of DDH functionals depends (self-consistently) on the dielectric constant of the material. In the present talk we introduce a range-separated (RS) version of DDH functionals where short and long-range components are matched using material dependent, non-empirical parameters. Comparing with state of the art GW calculations and experiment, we show that such RS hybrids yield accurate electronic properties of both molecules and solids, including energy gaps, photoelectron spectra and absolute ionization potentials. This work was supported by NSF-CCI Grant Number NSF-CHE-0802907 and DOE-BES.
A Cavity Corrected 3D-RISM Functional for Accurate Solvation Free Energies
2014-01-01
We show that an Ng bridge function modified version of the three-dimensional reference interaction site model (3D-RISM-NgB) solvation free energy method can accurately predict the hydration free energy (HFE) of a set of 504 organic molecules. To achieve this, a single unique constant parameter was adjusted to the computed HFE of single atom Lennard-Jones solutes. It is shown that 3D-RISM is relatively accurate at predicting the electrostatic component of the HFE without correction but requires a modification of the nonpolar contribution that originates in the formation of the cavity created by the solute in water. We use a free energy functional with the Ng scaling of the direct correlation function [Ng, K. C. J. Chem. Phys.1974, 61, 2680]. This produces a rapid, reliable small molecule HFE calculation for applications in drug design. PMID:24634616
A Cavity Corrected 3D-RISM Functional for Accurate Solvation Free Energies.
Truchon, Jean-François; Pettitt, B Montgomery; Labute, Paul
2014-03-11
We show that an Ng bridge function modified version of the three-dimensional reference interaction site model (3D-RISM-NgB) solvation free energy method can accurately predict the hydration free energy (HFE) of a set of 504 organic molecules. To achieve this, a single unique constant parameter was adjusted to the computed HFE of single atom Lennard-Jones solutes. It is shown that 3D-RISM is relatively accurate at predicting the electrostatic component of the HFE without correction but requires a modification of the nonpolar contribution that originates in the formation of the cavity created by the solute in water. We use a free energy functional with the Ng scaling of the direct correlation function [Ng, K. C. J. Chem. Phys. 1974, 61, 2680]. This produces a rapid, reliable small molecule HFE calculation for applications in drug design. PMID:24634616
Toward Transfer Functions for Land Surface Phenologies
NASA Astrophysics Data System (ADS)
Henebry, G. M.
2010-12-01
A key problem in projecting future landscapes is simulating the associated land surface phenologies (or LSPs). A recent study of land surface models concluded that the representations of crop phenologies among the models diverged sufficiently to impede a useful intercomparison of simulation results from their associated climate models. Grassland phenologies are far more complicated than cropland phenologies due to multiple forcing factors, photosynthetic pathways (C3 vs C4), and spatial heterogeneities in both resource availabilities and land management practices. Furthermore, many tallgrass species (such as switchgrass) are widely distributed across temperature, but not moisture, gradients, resulting in significant ecotypic variation across the species' geographic range. Thus, how feasible is "transplanting" tallgrass LSPs across isotherms—but along isohyets—to simulate a shift in cultivation from maize-soy to switchgrass? Prior work has shown a quadratic model can provide a parsimonious link between a Normalized Difference Vegetation Index (or NDVI) time series and thermal time, measured in terms of accumulated growing degree-days (or AGDD). Moreover, the thermal time to peak NDVI (or TTP) is a simple function of the parameter coefficients of fitted model. I fitted quadratic models to MODIS NDVI and weather station data at multiple sites across the Northern Great Plains over ten growing seasons, 2000-2009. There is a strong latitudinal gradient in TTP that results in part from a quasi-linear gradient in accumulated daylight hours (or ADH) between 30 and 50 degrees north. However, AGDD improves upon ADH by providing sensitivity to the variability of growing season weather. In the quadratic parameter coefficients there is a geographic pattern apparent as a function of TTP, although it is more variable at shorter TTPs. Using these patterns, an LSP transfer function was implemented along a latitudinal transect to simulate switchgrass cultivation in areas now
The Evolution of a More Rigorous Approach to Benefit Transfer: Benefit Function Transfer
NASA Astrophysics Data System (ADS)
Loomis, John B.
1992-03-01
The desire for economic values of recreation for unstudied recreation resources dates back to the water resource development benefit-cost analyses of the early 1960s. Rather than simply applying existing estimates of benefits per trip to the study site, a fairly rigorous approach was developed by a number of economists. This approach involves application of travel cost demand equations and contingent valuation benefit functions from existing sites to the new site. In this way the spatial market of the new site (i.e., its differing own price, substitute prices and population distribution) is accounted for in the new estimate of total recreation benefits. The assumptions of benefit transfer from recreation sites in one state to another state for the same recreation activity is empirically tested. The equality of demand coefficients for ocean sport salmon fishing in Oregon versus Washington and for freshwater steelhead fishing in Oregon versus Idaho is rejected. Thus transfer of either demand equations or average benefits per trip are likely to be in error. Using the Oregon steelhead equation, benefit transfers to rivers within the state are shown to be accurate to within 5-15%.
Robust algorithm for estimation of time-varying transfer functions.
Zou, Rui; Chon, Ki H
2004-02-01
We introduce a new method to estimate reliable time-varying (TV) transfer functions (TFs) and TV impulse response functions. The method is based on TV autoregressive moving average models in which the TV parameters are accurately obtained using the optimal parameter search method which we have previously developed. The new method is more accurate than the recursive least-squares (RLS), and remains robust even in the case of significant noise contamination. Furthermore, the new method is able to track dynamics that change abruptly, which is certainly a deficiency of the RLS. Application of the new method to renal blood pressure and flow revealed that hypertensive rats undergo more complex and TV autoregulation in maintaining stable blood flow than do normotensive rats. This observation has not been previously revealed using time-invariant TF analyses. The newly developed approach may promote the broader use of TV system identification in studies of physiological systems and makes linear and nonlinear TV modeling possible in certain cases previously thought intractable. PMID:14765694
Neural network identification of power system transfer functions
Gillard, D.M.; Bollinger, K.E.
1996-03-01
This paper describes an investigation into the use of a multilayered neural network for measuring the transfer function of a power system for use in power system stabilizer (PSS) tuning and assessing PSS damping. The objectives are to quickly and accurately measure the transfer function relating the electric power output to the AVR PSS reference voltage input of a system with the plant operating under normal conditions. In addition, the excitation signal used in the identification procedure is such that it will not adversely affect the terminal voltage or the system frequency. This research emphasized the development of a neural network that is easily trained and robust to changing system conditions. Performance studies of the trained neural network are described. Simulation studies suggest the practical feasibility of the algorithm as a stand-alone identification package and as a portion of a self-tuning algorithm requiring identification in the strategy. The same technique applied to a forward modeling scheme can be used to test the damping contribution from different control strategies.
NASA Astrophysics Data System (ADS)
Peng, Liang-You; Gong, Qihuang
2010-12-01
The accurate computations of hydrogenic continuum wave functions are very important in many branches of physics such as electron-atom collisions, cold atom physics, and atomic ionization in strong laser fields, etc. Although there already exist various algorithms and codes, most of them are only reliable in a certain ranges of parameters. In some practical applications, accurate continuum wave functions need to be calculated at extremely low energies, large radial distances and/or large angular momentum number. Here we provide such a code, which can generate accurate hydrogenic continuum wave functions and corresponding Coulomb phase shifts at a wide range of parameters. Without any essential restrict to angular momentum number, the present code is able to give reliable results at the electron energy range [10,10] eV for radial distances of [10,10] a.u. We also find the present code is very efficient, which should find numerous applications in many fields such as strong field physics. Program summaryProgram title: HContinuumGautchi Catalogue identifier: AEHD_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEHD_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 1233 No. of bytes in distributed program, including test data, etc.: 7405 Distribution format: tar.gz Programming language: Fortran90 in fixed format Computer: AMD Processors Operating system: Linux RAM: 20 MBytes Classification: 2.7, 4.5 Nature of problem: The accurate computation of atomic continuum wave functions is very important in many research fields such as strong field physics and cold atom physics. Although there have already existed various algorithms and codes, most of them can only be applicable and reliable in a certain range of parameters. We present here an accurate FORTRAN program for
Satellite modulation transfer function estimation from natural scenes
NASA Astrophysics Data System (ADS)
Xiyang, Zhi; Wei, Zhang; Xuan, Sun; Dawei, Wang
2015-11-01
We propose an in-orbit modulation transfer function (MTF) statistical estimation algorithm based on natural scene, called SeMTF. The algorithm can estimate the in-orbit MTF of a sensor from an image without specialized targets. First, the power spectrum of a satellite image is analyzed, then a two-dimensional (2-D) fractal Brownian motion model is adopted to represent the natural scene. The in-orbit MTF is modeled by a parametric exponential function. Subsequently, the statistical model of satellite imaging is established. Second, the model is solved by the improved profile-likelihood function method. In order to handle the nuisance parameter in the profile-likelihood function, we divided the estimation problem into two minimization problems for the parameters of the MTF model and nuisance parameters, respectively. By alternating the two iterative minimizations, the result will converge to the optimal MTF parameters. Then the SeMTF algorithm is proposed. Finally, the algorithm is tested using real satellite images. Experimental results indicate that the estimation of MTF is highly accurate.
Transfer Function Design for Scientific Discovery
Jian Huang
2008-12-08
As computation scales beyond terascale, the scientific problems under study through computing are increasingly pushing the boundaries of human knowledge about the physical world. It is more pivotal than ever to quickly and reliably extract new knowledge from these complex simulations of ultra scale. In this project, the PI expanded the traditional notion of transfer function, which maps physical quantities to visual cues via table look-ups, to include general temporal as well as multivariate patterns that can be described procedurally through specialty mini programming languages. Their efforts aimed at answering a perpetual question of fundamental importance. That is "what a visualization should show". Instead of waiting for application scientists to initiate the process, the team at University of Tennessee worked closely with scientists at ORNL in a proactive role to envision and design elegant, powerful, and reliable tools that a user can use to specify "what is interesting". Their new techniques include visualization operators that revolve around correlation and graph properties, relative patterns in statistical distribution, temporal regular expressions, concurrent attribute subspaces and traditional compound boolean range queries. The team also paid special attention to ensure that all visualization operators are inherently designed with great parallel scalability to handle tera-scale datasets in both homogeneous and heterogeneous environments. Success has been demonstrated with leading edge computational science areas include climate modeling, combustion and systems genetics.
Atmospheric modulation transfer function in the infrared.
Buskila, Kobi; Towito, Shay; Shmuel, Elad; Levi, Ran; Kopeika, Natan; Krapels, Keith; Driggers, Ronald G; Vollmerhausen, Richard H; Halford, Carl E
2004-01-10
In high-resolution ultranarrow field-of-view thermal imagers, image quality over relatively long path lengths is typically limited by atmospheric degradation, especially atmospheric blur. We report our results and analyses of infrared images from two sites, Fort A. P. Hill and Aberdeen Proving Ground. The images are influenced by the various atmospheric phenomena: scattering, absorption, and turbulence. A series of experiments with high-resolution equipment in both the 3-5- and 8-13-microm regions at the two locations indicate that, as in the visible, image quality is limited much more by atmosphere than by the instrumentation for ranges even of the order of only a few kilometers. For paths close to the ground, turbulence is more dominant, whereas for paths involving higher average elevation, aerosol modulation transfer function (MTF) is dominant. As wavelength increases, turbulence MTF also increases, thus permitting aerosol MTF to become more dominant. A critical role in aerosol MTF in the thermal infrared is attributed to absorption, which noticeably decreases atmospheric transmission much more than in the visible, thereby reducing high-spatial-frequency aerosol MTF. These measurements indicate that atmospheric MTF should be a basic component in imaging system design and analysis even in the infrared, especially as higher-resolution hardware becomes available. PMID:14735966
The Modulation Transfer Function for Speech Intelligibility
Elliott, Taffeta M.; Theunissen, Frédéric E.
2009-01-01
We systematically determined which spectrotemporal modulations in speech are necessary for comprehension by human listeners. Speech comprehension has been shown to be robust to spectral and temporal degradations, but the specific relevance of particular degradations is arguable due to the complexity of the joint spectral and temporal information in the speech signal. We applied a novel modulation filtering technique to recorded sentences to restrict acoustic information quantitatively and to obtain a joint spectrotemporal modulation transfer function for speech comprehension, the speech MTF. For American English, the speech MTF showed the criticality of low modulation frequencies in both time and frequency. Comprehension was significantly impaired when temporal modulations <12 Hz or spectral modulations <4 cycles/kHz were removed. More specifically, the MTF was bandpass in temporal modulations and low-pass in spectral modulations: temporal modulations from 1 to 7 Hz and spectral modulations <1 cycles/kHz were the most important. We evaluated the importance of spectrotemporal modulations for vocal gender identification and found a different region of interest: removing spectral modulations between 3 and 7 cycles/kHz significantly increases gender misidentifications of female speakers. The determination of the speech MTF furnishes an additional method for producing speech signals with reduced bandwidth but high intelligibility. Such compression could be used for audio applications such as file compression or noise removal and for clinical applications such as signal processing for cochlear implants. PMID:19266016
Kim, K.T.; Lee, J.G.; Quay, B.D.; Santavicca, D.A.
2010-09-15
The present paper describes a methodology to improve the accuracy of prediction of the eigenfrequencies and growth rates of self-induced instabilities and demonstrates its application to a laboratory-scale, swirl-stabilized, lean-premixed, gas turbine combustor. The influence of the spatial heat release distribution is accounted for using local flame transfer function (FTF) measurements. The two-microphone technique and CH{sup *} chemiluminescence intensity measurements are used to determine the input (inlet velocity perturbation) and the output functions (heat release oscillation), respectively, for the local flame transfer functions. The experimentally determined local flame transfer functions are superposed using the flame transfer function superposition principle, and the result is incorporated into an analytic thermoacoustic model, in order to predict the linear stability characteristics of a given system. Results show that when the flame length is not acoustically compact the model prediction calculated using the local flame transfer functions is better than the prediction made using the global flame transfer function. In the case of a flame in the compact flame regime, accurate predictions of eigenfrequencies and growth rates can be obtained using the global flame transfer function. It was also found that the general response characteristics of the local FTF (gain and phase) are qualitatively the same as those of the global FTF. (author)
SUTO, Noriko; HARADA, Makoto; IZUTSU, Jun; NAGAO, Toshiyasu
2006-01-01
In order to accurately estimate the geomagnetic transfer functions in the area of the volcano Mt. Iwate (IWT), we applied the interstation transfer function (ISTF) method to the three-component geomagnetic field data observed at Mt. Iwate station (IWT), using the Kakioka Magnetic Observatory, JMA (KAK) as remote reference station. Instead of the conventional Fourier transform, in which temporary transient noises badly degrade the accuracy of long term properties, continuous wavelet transform has been used. The accuracy of the results was as high as that of robust estimations of transfer functions obtained by the Fourier transform method. This would provide us with possibilities for routinely monitoring the transfer functions, without sophisticated statistical procedures, to detect changes in the underground electrical conductivity structure. PMID:25792780
Computer method for identification of boiler transfer functions
NASA Technical Reports Server (NTRS)
Miles, J. H.
1971-01-01
An iterative computer method is described for identifying boiler transfer functions using frequency response data. An objective penalized performance measure and a nonlinear minimization technique are used to cause the locus of points generated by a transfer function to resemble the locus of points obtained from frequency response measurements. Different transfer functions can be tried until a satisfactory empirical transfer function to the system is found. To illustrate the method, some examples and some results from a study of a set of data consisting of measurements of the inlet impedance of a single tube forced flow boiler with inserts are given.
NASA Astrophysics Data System (ADS)
Skone, Jonathan; Govoni, Marco; Galli, Giulia
2015-03-01
Building upon a recently proposed self-consistent hybrid (sc-hybrid) functional, where the optimal dielectric screening is included self-consistently, we propose an improved form by incorporating range-separation of the exchange part. We discuss the choice of the non-empirical parameters defining range separation, and we present results for condensed media including semiconductors, amorphous insulators, and molecular crystals. We find that the range-separated sc-hybrid functional further improves upon the electronic gaps obtained with full-range sc-hybrids, thus providing an accurate functional for high throughput band gap engineering. This work was supported by NSF-CCI Grant Number NSF-CHE-0802907 and ARL Grant Number W911NF-12-2-0023.
Application of the spectrally integrated Voigt function to line-by-line radiative transfer modelling
NASA Astrophysics Data System (ADS)
Quine, B. M.; Abrarov, S. M.
2013-09-01
We show that a new approach based on the spectrally integrated Voigt function (SIVF) enables the computation of line-by-line (LBL) radiative transfer at reduced spectral resolution without loss of accuracy. The algorithm provides rapid and accurate computation of area under the Voigt function in a way that preserves spectral radiance and, consequently, radiant intensity. The error analysis we provide shows the high-accuracy of the proposed SIVF approximations. A comparison of the performance of the method with that of the traditional LBL approach is presented. Motivations for the use and advantage of the SIVF as a replacement for conventional line function computations in radiative transfer are discussed.
Do Bond Functions Help for the Calculation of Accurate Bond Energies?
NASA Technical Reports Server (NTRS)
Bauschlicher, Charles W., Jr.; Arnold, James (Technical Monitor)
1998-01-01
The bond energies of 8 chemically bound diatomics are computed using several basis sets with and without bond functions (BF). The bond energies obtained using the aug-pVnZ+BF basis sets (with a correction for basis set superposition error, BSSE) tend to be slightly smaller that the results obtained using the aug-pV(n+I)Z basis sets, but slightly larger than the BSSE corrected aug-pV(n+I)Z results. The aug-cc-pVDZ+BF and aug-cc-pVTZ+BF basis sets yield reasonable estimates of bond energies, but, in most cases, these results cannot be considered highly accurate. Extrapolation of the results obtained with basis sets including bond functions appears to be inferior to the results obtained by extrapolation using atom-centered basis sets. Therefore bond functions do not appear to offer a path for obtaining highly accurate results for chemically bound systems at a lower computational cost than atom centered basis sets.
NASA Technical Reports Server (NTRS)
Lee, Timothy J.; Dateo, Christopher E.; Schwenke, David W.; Chaban, Galina M.
2005-01-01
Accurate quartic force fields have been determined for the CCH- and NH2- molecular anions using the singles and doubles coupled-cluster method that includes a perturbational estimate of the effects of connected triple excitations, CCSD(T). Very large one-particle basis sets have been used including diffuse functions and up through g-type functions. Correlation of the nitrogen and carbon core electrons has been included, as well as other "small" effects, such as the diagonal Born-Oppenheimer correction, and basis set extrapolation, and corrections for higher-order correlation effects and scalar relativistic effects. Fundamental vibrational frequencies have been computed using standard second-order perturbation theory as well as variational methods. Comparison with the available experimental data is presented and discussed. The implications of our research for the astronomical observation of molecular anions will be discussed.
Brandenburg, Jan Gerit; Caldeweyher, Eike; Grimme, Stefan
2016-06-21
We extend the recently introduced PBEh-3c global hybrid density functional [S. Grimme et al., J. Chem. Phys., 2015, 143, 054107] by a screened Fock exchange variant based on the Henderson-Janesko-Scuseria exchange hole model. While the excellent performance of the global hybrid is maintained for small covalently bound molecules, its performance for computed condensed phase mass densities is further improved. Most importantly, a speed up of 30 to 50% can be achieved and especially for small orbital energy gap cases, the method is numerically much more robust. The latter point is important for many applications, e.g., for metal-organic frameworks, organic semiconductors, or protein structures. This enables an accurate density functional based electronic structure calculation of a full DNA helix structure on a single core desktop computer which is presented as an example in addition to comprehensive benchmark results. PMID:27240749
16 CFR 1750.2 - Transfer of functions.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Transfer of functions. 1750.2 Section 1750.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION REFRIGERATOR SAFETY ACT REGULATIONS STANDARD FOR DEVICES TO PERMIT THE OPENING OF HOUSEHOLD REFRIGERATOR DOORS FROM THE INSIDE § 1750.2 Transfer of functions. Effective May 14, 1973, section...
SIFTER search: a web server for accurate phylogeny-based protein function prediction.
Sahraeian, Sayed M; Luo, Kevin R; Brenner, Steven E
2015-07-01
We are awash in proteins discovered through high-throughput sequencing projects. As only a minuscule fraction of these have been experimentally characterized, computational methods are widely used for automated annotation. Here, we introduce a user-friendly web interface for accurate protein function prediction using the SIFTER algorithm. SIFTER is a state-of-the-art sequence-based gene molecular function prediction algorithm that uses a statistical model of function evolution to incorporate annotations throughout the phylogenetic tree. Due to the resources needed by the SIFTER algorithm, running SIFTER locally is not trivial for most users, especially for large-scale problems. The SIFTER web server thus provides access to precomputed predictions on 16 863 537 proteins from 232 403 species. Users can explore SIFTER predictions with queries for proteins, species, functions, and homologs of sequences not in the precomputed prediction set. The SIFTER web server is accessible at http://sifter.berkeley.edu/ and the source code can be downloaded. PMID:25979264
Schütt, Heiko H; Harmeling, Stefan; Macke, Jakob H; Wichmann, Felix A
2016-05-01
The psychometric function describes how an experimental variable, such as stimulus strength, influences the behaviour of an observer. Estimation of psychometric functions from experimental data plays a central role in fields such as psychophysics, experimental psychology and in the behavioural neurosciences. Experimental data may exhibit substantial overdispersion, which may result from non-stationarity in the behaviour of observers. Here we extend the standard binomial model which is typically used for psychometric function estimation to a beta-binomial model. We show that the use of the beta-binomial model makes it possible to determine accurate credible intervals even in data which exhibit substantial overdispersion. This goes beyond classical measures for overdispersion-goodness-of-fit-which can detect overdispersion but provide no method to do correct inference for overdispersed data. We use Bayesian inference methods for estimating the posterior distribution of the parameters of the psychometric function. Unlike previous Bayesian psychometric inference methods our software implementation-psignifit 4-performs numerical integration of the posterior within automatically determined bounds. This avoids the use of Markov chain Monte Carlo (MCMC) methods typically requiring expert knowledge. Extensive numerical tests show the validity of the approach and we discuss implications of overdispersion for experimental design. A comprehensive MATLAB toolbox implementing the method is freely available; a python implementation providing the basic capabilities is also available. PMID:27013261
SIFTER search: a web server for accurate phylogeny-based protein function prediction
Sahraeian, Sayed M.; Luo, Kevin R.; Brenner, Steven E.
2015-05-15
We are awash in proteins discovered through high-throughput sequencing projects. As only a minuscule fraction of these have been experimentally characterized, computational methods are widely used for automated annotation. Here, we introduce a user-friendly web interface for accurate protein function prediction using the SIFTER algorithm. SIFTER is a state-of-the-art sequence-based gene molecular function prediction algorithm that uses a statistical model of function evolution to incorporate annotations throughout the phylogenetic tree. Due to the resources needed by the SIFTER algorithm, running SIFTER locally is not trivial for most users, especially for large-scale problems. The SIFTER web server thus provides access to precomputed predictions on 16 863 537 proteins from 232 403 species. Users can explore SIFTER predictions with queries for proteins, species, functions, and homologs of sequences not in the precomputed prediction set. Lastly, the SIFTER web server is accessible at http://sifter.berkeley.edu/ and the source code can be downloaded.
SIFTER search: a web server for accurate phylogeny-based protein function prediction
Sahraeian, Sayed M.; Luo, Kevin R.; Brenner, Steven E.
2015-05-15
We are awash in proteins discovered through high-throughput sequencing projects. As only a minuscule fraction of these have been experimentally characterized, computational methods are widely used for automated annotation. Here, we introduce a user-friendly web interface for accurate protein function prediction using the SIFTER algorithm. SIFTER is a state-of-the-art sequence-based gene molecular function prediction algorithm that uses a statistical model of function evolution to incorporate annotations throughout the phylogenetic tree. Due to the resources needed by the SIFTER algorithm, running SIFTER locally is not trivial for most users, especially for large-scale problems. The SIFTER web server thus provides access tomore » precomputed predictions on 16 863 537 proteins from 232 403 species. Users can explore SIFTER predictions with queries for proteins, species, functions, and homologs of sequences not in the precomputed prediction set. Lastly, the SIFTER web server is accessible at http://sifter.berkeley.edu/ and the source code can be downloaded.« less
NASA Astrophysics Data System (ADS)
Jolivet, L.; Cohen, M.; Ruas, A.
2015-08-01
Landscape influences fauna movement at different levels, from habitat selection to choices of movements' direction. Our goal is to provide a development frame in order to test simulation functions for animal's movement. We describe our approach for such simulations and we compare two types of functions to calculate trajectories. To do so, we first modelled the role of landscape elements to differentiate between elements that facilitate movements and the ones being hindrances. Different influences are identified depending on landscape elements and on animal species. Knowledge were gathered from ecologists, literature and observation datasets. Second, we analysed the description of animal movement recorded with GPS at fine scale, corresponding to high temporal frequency and good location accuracy. Analysing this type of data provides information on the relation between landscape features and movements. We implemented an agent-based simulation approach to calculate potential trajectories constrained by the spatial environment and individual's behaviour. We tested two functions that consider space differently: one function takes into account the geometry and the types of landscape elements and one cost function sums up the spatial surroundings of an individual. Results highlight the fact that the cost function exaggerates the distances travelled by an individual and simplifies movement patterns. The geometry accurate function represents a good bottom-up approach for discovering interesting areas or obstacles for movements.
Perfect function transfer in two and three dimensions without initialization
Wu Lianao; Byrd, Mark; Wang, Z. D.; Shao Bin
2010-11-15
We find analytic models that can perfectly transfer, without state initialization or remote collaboration, arbitrary functions in two- and three-dimensional interacting bosonic and fermionic networks. This provides for the possible experimental implementation of state transfer through bosonic or fermionic atoms trapped in optical lattices. A significant finding is that the state of a spin qubit can be perfectly transferred through a fermionic system. Families of Hamiltonians are described that are related to the linear models and that enable the perfect transfer of arbitrary functions. Furthermore, we propose methods for eliminating certain types of errors.
Determining A Purely Symbolic Transfer Function from Symbol Streams: Theory and Algorithms
Griffin, Christopher H
2008-01-01
Transfer function modeling is a \\emph{standard technique} in classical Linear Time Invariant and Statistical Process Control. The work of Box and Jenkins was seminal in developing methods for identifying parameters associated with classical $(r,s,k)$ transfer functions. Discrete event systems are often \\emph{used} for modeling hybrid control structures and high-level decision problems. \\emph{Examples include} discrete time, discrete strategy repeated games. For these games, a \\emph{discrete transfer function in the form of} an accurate hidden Markov model of input-output relations \\emph{could be used to derive optimal response strategies.} In this paper, we develop an algorithm \\emph{for} creating probabilistic \\textit{Mealy machines} that act as transfer function models for discrete event dynamic systems (DEDS). Our models are defined by three parameters, $(l_1, l_2, k)$ just as the Box-Jenkins transfer function models. Here $l_1$ is the maximal input history lengths to consider, $l_2$ is the maximal output history lengths to consider and $k$ is the response lag. Using related results, We show that our Mealy machine transfer functions are optimal in the sense that they maximize the mutual information between the current known state of the DEDS and the next observed input/output pair.
Tung, Wei-Cheng; Adamowicz, Ludwik
2014-03-28
Very accurate calculations of the ground-state potential energy curve (PEC) of the LiH(+) ion performed with all-electron explicitly correlated Gaussian functions with shifted centers are presented. The variational method is employed. The calculations involve optimization of nonlinear exponential parameters of the Gaussians performed with the aid of the analytical first derivatives of the energy determined with respect to the parameters. The diagonal adiabatic correction is also calculated for each PEC point. The PEC is then used to calculate the vibrational energies of the system. In that calculation, the non-adiabatic effects are accounted for by using an effective vibrational mass obtained by the minimization of the difference between the vibrational energies obtained from the calculations where the Born-Oppenheimer approximation was not assumed and the results of the present calculations. PMID:24697449
NASA Astrophysics Data System (ADS)
Tung, Wei-Cheng; Adamowicz, Ludwik
2014-03-01
Very accurate calculations of the ground-state potential energy curve (PEC) of the LiH+ ion performed with all-electron explicitly correlated Gaussian functions with shifted centers are presented. The variational method is employed. The calculations involve optimization of nonlinear exponential parameters of the Gaussians performed with the aid of the analytical first derivatives of the energy determined with respect to the parameters. The diagonal adiabatic correction is also calculated for each PEC point. The PEC is then used to calculate the vibrational energies of the system. In that calculation, the non-adiabatic effects are accounted for by using an effective vibrational mass obtained by the minimization of the difference between the vibrational energies obtained from the calculations where the Born-Oppenheimer approximation was not assumed and the results of the present calculations.
Multivariable synthesis with transfer functions. [applications to gas turbine engines
NASA Technical Reports Server (NTRS)
Peczkowski, J. L.
1980-01-01
A transfer function design theory for multivariable control synthesis is highlighted. The use of unique transfer function matrices and two simple, basic relationships - a synthesis equation and a design equation - are presented and illustrated. This multivariable transfer function approach provides the designer with a capability to specify directly desired dynamic relationships between command variables and controlled or response variables. At the same time, insight and influence over response, simplifications, and internal stability is afforded by the method. A general, comprehensive multivariable synthesis capability is indicated including nonminmum phase and unstable plants. Gas turbine engine examples are used to illustrate the ideas and method.
High Ulnar Nerve Injuries: Nerve Transfers to Restore Function.
Patterson, Jennifer Megan M
2016-05-01
Peripheral nerve injuries are challenging problems. Nerve transfers are one of many options available to surgeons caring for these patients, although they do not replace tendon transfers, nerve graft, or primary repair in all patients. Distal nerve transfers for the treatment of high ulnar nerve injuries allow for a shorter reinnervation period and improved ulnar intrinsic recovery, which are critical to function of the hand. PMID:27094893
MODELING ENVIRONMENTAL TOBACCO SMOKE IN THE HOME USING TRANSFER FUNCTIONS
This paper presents the theoretical and practical development of a multi-compartment indoor air quality model designed for predicting pollutant concentrations from environmental tobacco smoke (ETS) in the home. he model is developed using transfer functions for each compartment, ...
Newton algorithm for fitting transfer functions to frequency response measurements
NASA Technical Reports Server (NTRS)
Spanos, J. T.; Mingori, D. L.
1993-01-01
In this paper the problem of synthesizing transfer functions from frequency response measurements is considered. Given a complex vector representing the measured frequency response of a physical system, a transfer function of specified order is determined that minimizes the sum of the magnitude-squared of the frequency response errors. This nonlinear least squares minimization problem is solved by an iterative global descent algorithm of the Newton type that converges quadratically near the minimum. The unknown transfer function is expressed as a sum of second-order rational polynomials, a parameterization that facilitates a numerically robust computer implementation. The algorithm is developed for single-input, single-output, causal, stable transfer functions. Two numerical examples demonstrate the effectiveness of the algorithm.
Development of a transfer function method for dynamic stability measurement
NASA Technical Reports Server (NTRS)
Johnson, W.
1977-01-01
Flutter testing method based on transfer function measurements is developed. The error statistics of several dynamic stability measurement methods are reviewed. It is shown that the transfer function measurement controls the error level by averaging the data and correlating the input and output. The method also gives a direct estimate of the error in the response measurement. An algorithm is developed for obtaining the natural frequency and damping ratio of low damped modes of the system, using integrals of the transfer function in the vicinity of a resonant peak. Guidelines are given for selecting the parameters in the transfer function measurement. Finally, the dynamic stability measurement technique is applied to data from a wind tunnel test of a proprotor and wing model.
Predicting Transfer Performance: A Comparison of Competing Function Learning Models
ERIC Educational Resources Information Center
McDaniel, Mark A.; Dimperio, Eric; Griego, Jacqueline A.; Busemeyer, Jerome R.
2009-01-01
The population of linear experts (POLE) model suggests that function learning and transfer are mediated by activation of a set of prestored linear functions that together approximate the given function (Kalish, Lewandowsky, & Kruschke, 2004). In the extrapolation-association (EXAM) model, an exemplar-based architecture associates trained input…
Hatt, Mathieu; Cheze le Rest, Catherine; Descourt, Patrice; Dekker, Andre; De Ruysscher, Dirk; Oellers, Michel; Lambin, Philippe; Pradier, Olivier; Visvikis, Dimitris
2010-05-01
Purpose: Accurate contouring of positron emission tomography (PET) functional volumes is now considered crucial in image-guided radiotherapy and other oncology applications because the use of functional imaging allows for biological target definition. In addition, the definition of variable uptake regions within the tumor itself may facilitate dose painting for dosimetry optimization. Methods and Materials: Current state-of-the-art algorithms for functional volume segmentation use adaptive thresholding. We developed an approach called fuzzy locally adaptive Bayesian (FLAB), validated on homogeneous objects, and then improved it by allowing the use of up to three tumor classes for the delineation of inhomogeneous tumors (3-FLAB). Simulated and real tumors with histology data containing homogeneous and heterogeneous activity distributions were used to assess the algorithm's accuracy. Results: The new 3-FLAB algorithm is able to extract the overall tumor from the background tissues and delineate variable uptake regions within the tumors, with higher accuracy and robustness compared with adaptive threshold (T{sub bckg}) and fuzzy C-means (FCM). 3-FLAB performed with a mean classification error of less than 9% +- 8% on the simulated tumors, whereas binary-only implementation led to errors of 15% +- 11%. T{sub bckg} and FCM led to mean errors of 20% +- 12% and 17% +- 14%, respectively. 3-FLAB also led to more robust estimation of the maximum diameters of tumors with histology measurements, with <6% standard deviation, whereas binary FLAB, T{sub bckg} and FCM lead to 10%, 12%, and 13%, respectively. Conclusion: These encouraging results warrant further investigation in future studies that will investigate the impact of 3-FLAB in radiotherapy treatment planning, diagnosis, and therapy response evaluation.
Transfer function analysis in epi-illumination Fourier ptychography
Pacheco, Shaun; Salahieh, Basel; Milster, Tom; Rodriguez, Jeffrey J.; Liang, Rongguang
2016-01-01
This letter explores Fourier ptychography (FP) using epi-illumination. The approach effectively modifies the FP transfer function to be coherent-like out to the incoherent limit of twice the numerical aperture over the wavelength 2NA/λ. Images reconstructed using this approach are shown to have higher contrast at finer details compared with images using incoherent illumination, indicating that the FP transfer function is superior in high spatial frequency regions. PMID:26565870
NASA Technical Reports Server (NTRS)
Susskind, J.; Rosenfield, J.; Reuter, D.
1983-01-01
The direct computation of atmospheric transmittance and clear column radiances for the channels of HIRS2 and MSU as a function of atmospheric and surface conditions is described in detail. A comparison is made between the observations and the calculated radiances derived from colocated oceanic radiosondes. It is found that under clear conditions, calculated brightness temperatures for the HIRS2 have a standard deviation of the order of 0.7 C compared with observations, whereas MSU channels have a standard deviation of approximately 1 C. In some channels, small biases are found that can be removed by an empirical 'tuning' with coefficients that can be successfully transferred from one season to another. Less satisfactory agreement is obtained from a comparison of calculations with 'reconstructed' clear radiances, which are used in analyzing sounding data under partially cloudy conditions.
Sun, Y. Y.; Kim, Y. H.; Lee, K.; Zhang, S. B.
2008-01-01
Density functional theory (DFT) in the commonly used local density or generalized gradient approximation fails to describe van der Waals (vdW) interactions that are vital to organic, biological, and other molecular systems. Here, we propose a simple, efficient, yet accurate local atomic potential (LAP) approach, named DFT+LAP, for including vdW interactions in the framework of DFT. The LAPs for H, C, N, and O are generated by fitting the DFT+LAP potential energy curves of small molecule dimers to those obtained from coupled cluster calculations with single, double, and perturbatively treated triple excitations, CCSD(T). Excellent transferability of the LAPs is demonstrated by remarkable agreement with the JSCH-2005 benchmark database [P. Jurecka et al. Phys. Chem. Chem. Phys. 8, 1985 (2006)], which provides the interaction energies of CCSD(T) quality for 165 vdW and hydrogen-bonded complexes. For over 100 vdW dominant complexes in this database, our DFT+LAP calculations give a mean absolute deviation from the benchmark results less than 0.5 kcal/mol. The DFT+LAP approach involves no extra computational cost other than standard DFT calculations and no modification of existing DFT codes, which enables straightforward quantum simulations, such as ab initio molecular dynamics, on biomolecular systems, as well as on other organic systems.
Forward and reverse transfer function model synthesis
NASA Technical Reports Server (NTRS)
Houghton, J. R.
1985-01-01
A process for synthesizing a mathematical model for a linear mechanical system using the forward and reverse Fourier transform functions is described. The differential equation for a system model is given. The Bode conversion of the differential equation, and the frequency and time-domain optimization matching of the model to the forward and reverse transform functions using the geometric simplex method of Nelder and Mead (1965) are examined. The effect of the window function on the linear mechanical system is analyzed. The model is applied to two examples; in one the signal damps down before the end of the time window and in the second the signal has significant energy at the end of the time window.
The Transfer Functions of Cardiac Tissue during Stochastic Pacing
de Lange, Enno; Kucera, Jan P.
2009-01-01
Abstract The restitution properties of cardiac action potential duration (APD) and conduction velocity (CV) are important factors in arrhythmogenesis. They determine alternans, wavebreak, and the patterns of reentrant arrhythmias. We developed a novel approach to characterize restitution using transfer functions. Transfer functions relate an input and an output quantity in terms of gain and phase shift in the complex frequency domain. We derived an analytical expression for the transfer function of interbeat intervals (IBIs) during conduction from one site (input) to another site downstream (output). Transfer functions can be efficiently obtained using a stochastic pacing protocol. Using simulations of conduction and extracellular mapping of strands of neonatal rat ventricular myocytes, we show that transfer functions permit the quantification of APD and CV restitution slopes when it is difficult to measure APD directly. We find that the normally positive CV restitution slope attenuates IBI variations. In contrast, a negative CV restitution slope (induced by decreasing extracellular [K+]) amplifies IBI variations with a maximum at the frequency of alternans. Hence, it potentiates alternans and renders conduction unstable, even in the absence of APD restitution. Thus, stochastic pacing and transfer function analysis represent a powerful strategy to evaluate restitution and the stability of conduction. PMID:19134481
Modulation Transfer Function Measurement Using Three- and Four-bar Targets.
Boreman, G D; Yang, S
1995-12-01
Modulation-transfer-function (MTF) measurement often involves the use of three- and four-bar resolution targets. In the conversion of three- and four-bar image data to MTF, biased results can occur when we use series-expansion techniques appropriate for square-wave targets of infinite extent. For systems where the image data are digitally recorded, a convenient and accurate conversion of bar-target data to MTF can be performed using a Fourier-domain method. PMID:21068904
[Contrast transfer function of the visual system].
Pak, M A; Cleveland, S J
1991-09-01
Visually evoked potentials were used to determine the spatial contrast response function of the visual system and the visual acuity of the pigeon. The spatial contrast response describes the relationship between the contrast in a pattern of vertical stripes, whose luminance is a function of position, and the amplitude of the visually evoked response at various spatial frequencies for a given temporal frequency (pattern reversal frequency); it indicates how particular spatial frequencies are attenuated in the visual system. The visually evoked responses were recorded using monopolar stainless steel electrodes inserted into the stratum griseum superficiale of the optic tectum; the depth of penetration was determined on the basis of a stereotactic atlas. The stimulus patterns were generated on a video monitor placed 75 cm in front of the animal's eye perpendicular to the optic axis. The spatial contrast response function measured at 10% contrast and 0.5 Hz reversal frequency shows a peak at a spatial frequency of 0.5 c/deg, corresponding to 1 degree of visual angle, and decreases progressively at higher spatial frequencies. The high-frequency limit (cut-off frequency) for resolution of sinusoidal gratings, estimated from the contrast response function, is 15.5 c/deg, corresponding to a visual acuity of 1.9 min of arc. PMID:1657228
Green's function solution to heat transfer of a transparent gas through a tube
NASA Technical Reports Server (NTRS)
Frankel, J. I.
1989-01-01
A heat transfer analysis of a transparent gas flowing through a circular tube of finite thickness is presented. This study includes the effects of wall conduction, internal radiative exchange, and convective heat transfer. The natural mathematical formulation produces a nonlinear, integrodifferential equation governing the wall temperature and an ordinary differential equation describing the gas temperature. This investigation proposes to convert the original system of equations into an equivalent system of integral equations. The Green's function method permits the conversion of an integrodifferential equation into a pure integral equation. The proposed integral formulation and subsequent computational procedure are shown to be stable and accurate.
Accurate Astrometry and Photometry of Saturated and Coronagraphic Point Spread Functions
Marois, C; Lafreniere, D; Macintosh, B; Doyon, R
2006-02-07
For ground-based adaptive optics point source imaging, differential atmospheric refraction and flexure introduce a small drift of the point spread function (PSF) with time, and seeing and sky transmission variations modify the PSF flux. These effects need to be corrected to properly combine the images and obtain optimal signal-to-noise ratios, accurate relative astrometry and photometry of detected companions as well as precise detection limits. Usually, one can easily correct for these effects by using the PSF core, but this is impossible when high dynamic range observing techniques are used, like coronagraphy with a non-transmissive occulting mask, or if the stellar PSF core is saturated. We present a new technique that can solve these issues by using off-axis satellite PSFs produced by a periodic amplitude or phase mask conjugated to a pupil plane. It will be shown that these satellite PSFs track precisely the PSF position, its Strehl ratio and its intensity and can thus be used to register and to flux normalize the PSF. This approach can be easily implemented in existing adaptive optics instruments and should be considered for future extreme adaptive optics coronagraph instruments and in high-contrast imaging space observatories.
Accurate calculation and modeling of the adiabatic connection in density functional theory
NASA Astrophysics Data System (ADS)
Teale, A. M.; Coriani, S.; Helgaker, T.
2010-04-01
AC. When parametrized in terms of the same input data, the AC-CI model offers improved performance over the corresponding AC-D model, which is shown to be the lowest-order contribution to the AC-CI model. The utility of the accurately calculated AC curves for the analysis of standard density functionals is demonstrated for the BLYP exchange-correlation functional and the interaction-strength-interpolation (ISI) model AC integrand. From the results of this analysis, we investigate the performance of our proposed two-parameter AC-D and AC-CI models when a simple density functional for the AC at infinite interaction strength is employed in place of information at the fully interacting point. The resulting two-parameter correlation functionals offer a qualitatively correct behavior of the AC integrand with much improved accuracy over previous attempts. The AC integrands in the present work are recommended as a basis for further work, generating functionals that avoid spurious error cancellations between exchange and correlation energies and give good accuracy for the range of densities and types of correlation contained in the systems studied here.
Parametric dependence of ocean wave-radar modulation transfer functions
NASA Technical Reports Server (NTRS)
Plant, W. J.; Keller, W. C.; Cross, A.
1983-01-01
Microwave techniques at X and L band were used to determine the dependence of ocean-wave radar modulation transfer functions (MTFs) on various environmental and radar parameters during the Marine Remote Sensing experiment of 1979 (MARSEN 79). These MIF are presented, as are coherence functions between the AM and FM parts of the backscattered microwave signal. It is shown that they both depend on several of these parameters. Besides confirming many of the properties of transfer functions reported by previous authors, indications are found that MTFs decrease with increasing angle between wave propagation and antenna-look directions but are essentially independent of small changes in air-sea temperature difference. However, coherence functions are much smaller when the antennas are pointed perpendicular to long waves. It is found that X band transfer functions measured with horizontally polarized microwave radiation have larger magnitudes than those obtained by using vertical polarization.
Förster-Induced Energy Transfer in Functionalized Graphene.
Malic, Ermin; Appel, Heiko; Hofmann, Oliver T; Rubio, Angel
2014-05-01
Carbon nanostructures are ideal substrates for functionalization with molecules since they consist of a single atomic layer giving rise to an extraordinary sensitivity to changes in their surrounding. The functionalization opens a new research field of hybrid nanostructures with tailored properties. Here, we present a microscopic view on the substrate-molecule interaction in the exemplary hybrid material consisting of graphene functionalized with perylene molecules. First experiments on similar systems have been recently realized illustrating an extremely efficient transfer of excitation energy from adsorbed molecules to the carbon substrate, a process with a large application potential for high-efficiency photovoltaic devices and biomedical imaging and sensing. So far, there has been no microscopically founded explanation for the observed energy transfer. Based on first-principle calculations, we have explicitly investigated the different transfer mechanisms revealing the crucial importance of Förster coupling. Due to the efficient Coulomb interaction in graphene, we obtain strong Förster rates in the range of 1/fs. We investigate its dependence on the substrate-molecule distance R and describe the impact of the momentum transfer q for an efficient energy transfer. Furthermore, we find that the Dexter transfer mechanism is negligibly small due to the vanishing overlap between the involved strongly localized orbital functions. The gained insights are applicable to a variety of carbon-based hybrid nanostructures. PMID:24808936
Förster-Induced Energy Transfer in Functionalized Graphene
2014-01-01
Carbon nanostructures are ideal substrates for functionalization with molecules since they consist of a single atomic layer giving rise to an extraordinary sensitivity to changes in their surrounding. The functionalization opens a new research field of hybrid nanostructures with tailored properties. Here, we present a microscopic view on the substrate–molecule interaction in the exemplary hybrid material consisting of graphene functionalized with perylene molecules. First experiments on similar systems have been recently realized illustrating an extremely efficient transfer of excitation energy from adsorbed molecules to the carbon substrate, a process with a large application potential for high-efficiency photovoltaic devices and biomedical imaging and sensing. So far, there has been no microscopically founded explanation for the observed energy transfer. Based on first-principle calculations, we have explicitly investigated the different transfer mechanisms revealing the crucial importance of Förster coupling. Due to the efficient Coulomb interaction in graphene, we obtain strong Förster rates in the range of 1/fs. We investigate its dependence on the substrate–molecule distance R and describe the impact of the momentum transfer q for an efficient energy transfer. Furthermore, we find that the Dexter transfer mechanism is negligibly small due to the vanishing overlap between the involved strongly localized orbital functions. The gained insights are applicable to a variety of carbon-based hybrid nanostructures. PMID:24808936
Autocorrelation method for measuring the transfer function of optical systems
NASA Astrophysics Data System (ADS)
Grover, C. P.; van Driel, H. M.
1980-03-01
An unconventional autocorrelation method is described for measuring the transfer function of optical systems. The interference takes place between the scattered waves obtained from two laterally sheared correlated partial diffusers. The output of a detector responding only to an extremely narrowband of spatial frequencies is proportional to the autocorrelation of the system pupil function. An automatic display of the transfer function is obtained by continuously varying the shear between the diffusers. The theory and some experimental results of this simple and inexpensive device are presented. A study of various parameters affecting the performance of the instrument is also given.
Transfer Functions Via Laplace- And Fourier-Borel Transforms
NASA Technical Reports Server (NTRS)
Can, Sumer; Unal, Aynur
1991-01-01
Approach to solution of nonlinear ordinary differential equations involves transfer functions based on recently-introduced Laplace-Borel and Fourier-Borel transforms. Main theorem gives transform of response of nonlinear system as Cauchy product of transfer function and transform of input function of system, together with memory effects. Used to determine responses of electrical circuits containing variable inductances or resistances. Also possibility of doing all noncommutative algebra on computers in such symbolic programming languages as Macsyma, Reduce, PL1, or Lisp. Process of solution organized and possibly simplified by algebraic manipulations reducing integrals in solutions to known or tabulated forms.
Optical transfer function of NTS-1 retroreflector array
NASA Technical Reports Server (NTRS)
Arnold, D. A.
1974-01-01
An optical transfer function was computed for the retroreflector array carried by the NTS-1 satellite. Range corrections are presented for extrapolating laser range measurements to the center of mass of the satellite. The gain function of the array was computed for use in estimating laser-echo signal strengths.
Applications of dispersion relations to the geomagnetic transfer function
NASA Astrophysics Data System (ADS)
Marcuello, A.; Queralt, P.; Ledo, J.
2005-05-01
The geomagnetic transfer function is nowadays used to constrain the magnetotelluric inversion procedure given that this function contains complementary information to the impedance tensor. For the models usually employed by inversions, the real and imaginary parts of the geomagnetic transfer function are related by dispersion relations. The computation of the dispersion relations involves the Hilbert transform, and here we discuss different expressions to compute them. This computation was verified using synthetically generated geomagnetic transfer function from 2D and 3D models. The dispersion relations were applied on two cases: (a) to study the consistency between the real and imaginary parts of field recorded data, and (b) to develop a procedure to complete or extend the amount of measured data.
Chen, Qiang; Yang, Bicheng
2016-01-01
By means of weight functions and Hermite-Hadamard's inequality, and introducing a discrete interval variable, a more accurate half-discrete Hardy-Hilbert-type inequality related to the kernel of arc tangent function and a best possible constant factor is given, which is an extension of a published result. The equivalent forms and the operator expressions are also considered. PMID:27563512
NASA Astrophysics Data System (ADS)
Hekkenberg, R. T.; Richards, A.; Beissner, K.; Zeqiri, B.; Prout, G.; Cantrall, Ch; Bezemer, R. A.; Koch, Ch; Hodnett, M.
2004-01-01
Physical therapy ultrasound is widely applied to patients. However, many devices do not comply with the relevant standard stating that the actual power output shall be within +/-20% of the device indication. Extreme cases have been reported: from delivering effectively no ultrasound or operating at maximum power at all powers indicated. This can potentially lead to patient injury as well as mistreatment. The present European (EC) project is an ongoing attempt to improve the quality of the treatment of patients being treated with ultrasonic physical-therapy. A Portable ultrasound Power Standard (PPS) is being developed and accurately calibrated. The PPS includes: Ultrasound transducers (including one exhibiting an unusual output) and a driver for the ultrasound transducers that has calibration and proficiency test functions. Also included with the PPS is a Cavitation Detector to determine the onset of cavitation occurring within the propagation medium. The PPS will be suitable for conducting in-the-field accreditation (proficiency testing and calibration). In order to be accredited it will be important to be able to show traceability of the calibration, the calibration process and qualification of testing staff. The clinical user will benefit from traceability because treatments will be performed more reliably.
Perfect function transfer and interference effects in interacting boson lattices
Wu Lianao; Miranowicz, Adam; Wang Xiangbin; Liu Yuxi; Nori, Franco
2009-07-15
We show how to perfectly transfer, without state initialization and remote collaboration, arbitrary functions in interacting boson lattices. We describe a possible implementation of state transfer through bosonic atoms trapped in optical lattices or polaritons in on-chip coupled cavities. Significantly, a family of Hamiltonians, both linear and nonlinear, is found which are related to the Bose-Hubbard model and that enable the perfect transfer of arbitrary functions. It is shown that the state transfer between two sites in two-dimensional lattices can result in quantum interference due to the different numbers of intermediate sites in different paths. The signature factor in nuclear physics can be useful to characterize this quantum interference.
Modulation transfer function of QWIP and superlattice focal plane arrays
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Rafol, S. B.; Ting, D. Z.; Soibel, A.; Liu, J. K.; Khoshakhlagh, A.; Keo, S. A.; Mumolo, J. M.; Nguyen, J.
2013-07-01
Modulation transfer function (MTF) is the ability of an imaging system to faithfully image a given object. The MTF of an imaging system quantifies the ability of the system to resolve or transfer spatial frequencies. In this paper we will discuss the detail MTF measurements of a 1024 × 1024 pixel multi-band quantum well infrared photodetector and 320 × 256 pixel long-wavelength InAs/GaSb superlattice infrared focal plane arrays.
Optical transfer function optimization based on linear expansions
NASA Astrophysics Data System (ADS)
Schwiegerling, Jim
2015-09-01
The Optical Transfer Function (OTF) and its modulus the Modulation Transfer Function (MTF) are metrics of optical system performance. However in system optimization, calculation times for the OTF are often substantially longer than more traditional optimization targets such as wavefront error or transverse ray error. The OTF is typically calculated as either the autocorrelation of the complex pupil function or as the Fourier transform of the Point Spread Function. We recently demonstrated that the on-axis OTF can be represented as a linear combination of analytical functions where the weighting terms are directly related to the wavefront error coefficients and apodization of the complex pupil function. Here, we extend this technique to the off-axis case. The expansion technique offers a potential for accelerating OTF optimization in lens design, as well as insight into the interaction of aberrations with components of the OTF.
H2 -norm of fractional transfer functions of implicit type
NASA Astrophysics Data System (ADS)
Malti, Rachid; Chevrié, Mathieu; Farges, Christophe; Sabatier, Jocelyn
2015-09-01
This paper studies the H2 -norm (or impulse response energy) of fractional transfer functions of implicit type. Stability conditions are first shown to be identical as in rational systems with all poles located in the open left half complex plane. Then, analytical expressions of the H2 -norm are derived for elementary fractional transfer functions of the first and the second kind cascaded with a pure fractional integrator. Next, general boundedness conditions are established in terms of transfer function relative degree. Three illustrative examples are finally proposed. The first one evaluates the quality of a rational approximation of a fractional model of implicit type on the basis of the H2 -norm of the error signal. The second one evaluates the Integral Squared Error of a CRONE control loop and compares it to a classical proportional-derivative controller in a vehicle suspension. Finally, the third one allows to set up an implicit fractional preshaping filter for closed-loop control.
The dynamic transfer function for a cavitating inducer
NASA Technical Reports Server (NTRS)
Brennen, C.; Acosta, A. J.
1975-01-01
Knowledge of the dynamic performance of pumps is essential for the prediction of transient behavior and instabilities in hydraulic systems; the necessary information is in the form of a transfer function which relates the instantaneous or fluctuating pressure and mass flow rate at inlet to the same quantities in the discharge from the pump. The presence of cavitation within the pump can have a major effect on this transfer function since dynamical changes in the volume of cavitation contribute to the difference in the instantaneous inlet and discharge mass flow rates. The present paper utilizes results from free streamline cascade theory to evaluate the elements in the transfer function for a cavitating inducer and shows that the numerical results are consistent with the characteristics observed in some dynamic tests on rocket engine turbopumps.
NASA Astrophysics Data System (ADS)
Seo, Dong-Hwa; Urban, Alexander; Ceder, Gerbrand
2015-09-01
Transition-metal (TM) oxides play an increasingly important role in technology today, including applications such as catalysis, solar energy harvesting, and energy storage. In many of these applications, the details of their electronic structure near the Fermi level are critically important for their properties. We propose a first-principles-based computational methodology for the accurate prediction of oxygen charge transfer in TM oxides and lithium TM (Li-TM) oxides. To obtain accurate electronic structures, the Heyd-Scuseria-Ernzerhof (HSE06) hybrid functional is adopted, and the amount of exact Hartree-Fock exchange (mixing parameter) is adjusted to reproduce reference band gaps. We show that the HSE06 functional with optimal mixing parameter yields not only improved electronic densities of states, but also better energetics (Li-intercalation voltages) for LiCo O2 and LiNi O2 as compared to the generalized gradient approximation (GGA), Hubbard U corrected GGA (GGA +U ), and standard HSE06. We find that the optimal mixing parameters for TM oxides are system specific and correlate with the covalency (ionicity) of the TM species. The strong covalent (ionic) nature of TM-O bonding leads to lower (higher) optimal mixing parameters. We find that optimized HSE06 functionals predict stronger hybridization of the Co 3 d and O 2 p orbitals as compared to GGA, resulting in a greater contribution from oxygen states to charge compensation upon delithiation in LiCo O2 . We also find that the band gaps of Li-TM oxides increase linearly with the mixing parameter, enabling the straightforward determination of optimal mixing parameters based on GGA (α =0.0 ) and HSE06 (α =0.25 ) calculations. Our results also show that G0W0@GGA +U band gaps of TM oxides (M O ,M =Mn ,Co ,Ni ) and LiCo O2 agree well with experimental references, suggesting that G0W0 calculations can be used as a reference for the calibration of the mixing parameter in cases when no experimental band gap has been
NASA Astrophysics Data System (ADS)
Brawand, Nicholas; Vörös, Márton; Govoni, Marco; Galli, Giulia
The accurate prediction of optoelectronic properties of molecules and solids is a persisting challenge for current density functional theory (DFT) based methods. We propose a hybrid functional where the mixing fraction of exact and local exchange is determined by a non-empirical, system dependent function. This functional yields ionization potentials, fundamental and optical gaps of many, diverse systems in excellent agreement with experiments, including organic and inorganic molecules and nanocrystals. We further demonstrate that the newly defined hybrid functional gives the correct alignment between the energy level of the exemplary TTF-TCNQ donor-acceptor system. DOE-BES: DE-FG02-06ER46262.
ERIC Educational Resources Information Center
Holton, James M.
During the 1990-91 academic year, Frederick Community College (FCC) in Maryland conducted a major research project to help determine the extent and effectiveness of the college's transfer function. In the study's first phase, a Transfer Tracking System (TTS) was developed by conducting a detailed audit of all transcript requests from FCC students.…
NASA Astrophysics Data System (ADS)
Javad Fahimi, Mohammad; Fathi, Davood; Ansari-Rad, Mehdi
2015-09-01
Electron transfer rate from quantum dot (QD) to metal oxide (MO) in quantum dot sensitized solar cells (QDSSCs) has an important role in the efficiency. In this work, we analyse the electron transfer rate from CdSe, CdS and CdTe QDs to TiO2, ZnO and SnO2 MOs by extending the related equations with considering various effects, based on the Marcus theory. In this regard, the effects of QD diameter, QD-MO spacing, the crystalline defects, temperature, and the reorganizational energy, on the electron transfer rate are investigated. The results show that, the maximum electron transfer rate is achieved for CdTe QD with the mentioned three MOs. Moreover, in order to direct the designer to reach the appropriate QDs-MOs combinations for obtaining the maximum electron transfer rate, the average electron transfer rate for various combinations is calculated. For the verification of simulation method, a part of work has been compared with the previous experimental and theoretical results, which indicates the correctness of our simulation algorithm.
Horizontal functional gene transfer from bacteria to fishes
Sun, Bao-Fa; Li, Tong; Xiao, Jin-Hua; Jia, Ling-Yi; Liu, Li; Zhang, Peng; Murphy, Robert W.; He, Shun-Min; Huang, Da-Wei
2015-01-01
Invertebrates can acquire functional genes via horizontal gene transfer (HGT) from bacteria but fishes are not known to do so. We provide the first reliable evidence of one HGT event from marine bacteria to fishes. The HGT appears to have occurred after emergence of the teleosts. The transferred gene is expressed and regulated developmentally. Its successful integration and expression may change the genetic and metabolic repertoire of fishes. In addition, this gene contains conserved domains and similar tertiary structures in fishes and their putative donor bacteria. Thus, it may function similarly in both groups. Evolutionary analyses indicate that it evolved under purifying selection, further indicating its conserved function. We document the first likely case of HGT of functional gene from prokaryote to fishes. This discovery certifies that HGT can influence vertebrate evolution. PMID:26691285
Determination of acoustical transfer functions using an impulse method
NASA Astrophysics Data System (ADS)
MacPherson, J.
1985-02-01
The Transfer Function of a system may be defined as the relationship of the output response to the input of a system. Whilst recent advances in digital processing systems have enabled Impulse Transfer Functions to be determined by computation of the Fast Fourier Transform, there has been little work done in applying these techniques to room acoustics. Acoustical Transfer Functions have been determined for auditoria, using an impulse method. The technique is based on the computation of the Fast Fourier Transform (FFT) of a non-ideal impulsive source, both at the source and at the receiver point. The Impulse Transfer Function (ITF) is obtained by dividing the FFT at the receiver position by the FFT of the source. This quantity is presented both as linear frequency scale plots and also as synthesized one-third octave band data. The technique enables a considerable quantity of data to be obtained from a small number of impulsive signals recorded in the field, thereby minimizing the time and effort required on site. As the characteristics of the source are taken into account in the calculation, the choice of impulsive source is non-critical. The digital analysis equipment required for the analysis is readily available commercially.
Track/train dynamics test procedure transfer function test
NASA Technical Reports Server (NTRS)
Vigil, R. A.
1975-01-01
A transfer function vibration test was made on an 80 ton open hopper freight car in an effort to obtain validation data on the car's nonlinear elastic model. Test configuration, handling, test facilities, test operations, and data acquisition/reduction activities necessary to meet the conditions of test requirements are given.
Modulation transfer function measurement using spatial noise targets
NASA Astrophysics Data System (ADS)
Boreman, Glenn D.
1995-06-01
In this paper, we consider the measurement of modulation transfer function (MTF) by means of spatially random, noise-like targets. We begin our discussion with the concept of shift- invariance and the measurement of MTF in pixelated systems. We then proceed to the methods for generation of these noise targets, using both laser speckle and transparency-based techniques.
Human transfer functions used to predict system performance parameters
NASA Technical Reports Server (NTRS)
1966-01-01
Automatic, parameter-tracking, model-matching technique compares the responses of a human operator with those of an analog computer model of a human operator to predict and analyze the performance of mechanical or electromechanical systems prior to construction. Transfer functions represent the input-output relation of an operator controlling a closed-loop system.
Naulleau, Patrick P; Gallatin, Gregg M
2003-06-10
The control of line-edge roughness (LER) of features printed in photoresist poses significant challenges to next-generation lithography techniques such as extreme-ultraviolet (EUV) lithography. Achieving adequately low LER levels will require accurate resist characterization as well as the ability to separate resist effects from other potential contributors to LER. One significant potential contributor is LER on the mask. Here we explicitly study the mask to resist LER coupling using both analytical and computer-simulation methods. We present what is to our knowledge a new imaging transfer function referred to as the LER transfer function (LTF), which fundamentally differs from both the conventional modulation transfer function and the optical transfer function. Moreover, we present experimental results demonstrating the impact of current EUV masks on projection-lithography-based LER experiments. PMID:12816326
Context transfer in reinforcement learning using action-value functions.
Mousavi, Amin; Nadjar Araabi, Babak; Nili Ahmadabadi, Majid
2014-01-01
This paper discusses the notion of context transfer in reinforcement learning tasks. Context transfer, as defined in this paper, implies knowledge transfer between source and target tasks that share the same environment dynamics and reward function but have different states or action spaces. In other words, the agents learn the same task while using different sensors and actuators. This requires the existence of an underlying common Markov decision process (MDP) to which all the agents' MDPs can be mapped. This is formulated in terms of the notion of MDP homomorphism. The learning framework is Q-learning. To transfer the knowledge between these tasks, the feature space is used as a translator and is expressed as a partial mapping between the state-action spaces of different tasks. The Q-values learned during the learning process of the source tasks are mapped to the sets of Q-values for the target task. These transferred Q-values are merged together and used to initialize the learning process of the target task. An interval-based approach is used to represent and merge the knowledge of the source tasks. Empirical results show that the transferred initialization can be beneficial to the learning process of the target task. PMID:25610457
Impact of permeability on seismoelectric transfer function of P waves
NASA Astrophysics Data System (ADS)
Holzhauer, J.; Bordes, C.; Oppermann, F.; Brito, D.; Yaramanci, U.
2012-04-01
Recent developments in the understanding of seismoelectrics have shown its potential relevance for porous media characterization with particular focus on permeability estimations. According to promising theoretical and numerical studies, permeability should influence the seismoelectric transfer function at higher frequencies. The dynamic seismoelectric transfer function E(ω)/ ü(ω), where E relates to the coseismic electric field induced by the seismic particle acceleration ü, is expected to increase with increasing permeabilities when crossing the Biot transition frequency. Still, only few experiments have been developed on that matter so far. To address the transfer function dependence on permeability, we adapted a column experiment to comply with steady-state permeability estimations. These observations were run in-situ, during the fluid-balancing phase prior to seismoelectric measurements. The 50 cm-long column had previously been carefully filled with perfectly rounded glass beads. The use of sorted glass beads is expected to achieve similar porosities reproducible throughout the experiment, opposed to varying permeabilities depending on the introduced particle size. The acoustic source delivered compressional waves with an optimal effect limited to the [1-3] kHz frequency range. These limitations are due to strong seismic attenuation in uncompacted porous media on one side, and to the dilemma of observing propagation in downsized laboratory setup on the other. First results validated the experimental protocol in terms of porosity/permeability independence: for particle size varying between 100 μm and 500 μm, permeability varied by a factor 20, with a maximum by 5.10-11 m2, while porosity remained by 39 ± 2 % during the whole experiment. Further investigations are being led regarding the normalised transfer function, corrected for both the fluid conductivity and the seismic energy. For that purpose, we compare the dependence of our measured transfer
NASA Technical Reports Server (NTRS)
Ko, William L.; Fleischer, Van Tran
2012-01-01
New first- and second-order displacement transfer functions have been developed for deformed shape calculations of nonuniform cross-sectional beam structures such as aircraft wings. The displacement transfer functions are expressed explicitly in terms of beam geometrical parameters and surface strains (uniaxial bending strains) obtained at equally spaced strain stations along the surface of the beam structure. By inputting the measured or analytically calculated surface strains into the displacement transfer functions, one could calculate local slopes, deflections, and cross-sectional twist angles of the nonuniform beam structure for mapping the overall structural deformed shapes for visual display. The accuracy of deformed shape calculations by the first- and second-order displacement transfer functions are determined by comparing these values to the analytically predicted values obtained from finite element analyses. This comparison shows that the new displacement transfer functions could quite accurately calculate the deformed shapes of tapered cantilever tubular beams with different tapered angles. The accuracy of the present displacement transfer functions also are compared to those of the previously developed displacement transfer functions.
A new class of atomic basis functions for accurate electronic structure calculations of molecules
NASA Astrophysics Data System (ADS)
Laikov, Dimitri N.
2005-11-01
A new general approach is developed for obtaining systematic sequences of atomic single-particle basis sets for use in correlated electronic structure calculations of molecules. All the constituent functions are defined as the solutions of variational problems and are of three types: a minimal Hartree-Fock set, additional functions to represent low-lying excited configurations, and general functions for describing electron correlation. The latter are determined to minimize a functional derived from the closed-shell second-order correlation energy expression. Generally-contracted Gaussian expansions are developed to approximate these general functions in the non-relativistic case and within a scalar-relativistic approximation.
A simple transfer function for nonlinear dendritic integration
Singh, Matthew F.; Zald, David H.
2015-01-01
Relatively recent advances in patch clamp recordings and iontophoresis have enabled unprecedented study of neuronal post-synaptic integration (“dendritic integration”). Findings support a separate layer of integration in the dendritic branches before potentials reach the cell's soma. While integration between branches obeys previous linear assumptions, proximal inputs within a branch produce threshold nonlinearity, which some authors have likened to the sigmoid function. Here we show the implausibility of a sigmoidal relation and present a more realistic transfer function in both an elegant artificial form and a biophysically derived form that further considers input locations along the dendritic arbor. As the distance between input locations determines their ability to produce nonlinear interactions, models incorporating dendritic topology are essential to understanding the computational power afforded by these early stages of integration. We use the biophysical transfer function to emulate empirical data using biophysical parameters and describe the conditions under which the artificial and biophysically derived forms are equivalent. PMID:26321940
Transfer function analysis of dynamic cerebral autoregulation in humans
NASA Technical Reports Server (NTRS)
Zhang, R.; Zuckerman, J. H.; Giller, C. A.; Levine, B. D.; Blomqvist, C. G. (Principal Investigator)
1998-01-01
To test the hypothesis that spontaneous changes in cerebral blood flow are primarily induced by changes in arterial pressure and that cerebral autoregulation is a frequency-dependent phenomenon, we measured mean arterial pressure in the finger and mean blood flow velocity in the middle cerebral artery (VMCA) during supine rest and acute hypotension induced by thigh cuff deflation in 10 healthy subjects. Transfer function gain, phase, and coherence function between changes in arterial pressure and VMCA were estimated using the Welch method. The impulse response function, calculated as the inverse Fourier transform of this transfer function, enabled the calculation of transient changes in VMCA during acute hypotension, which was compared with the directly measured change in VMCA during thigh cuff deflation. Beat-to-beat changes in VMCA occurred simultaneously with changes in arterial pressure, and the autospectrum of VMCA showed characteristics similar to arterial pressure. Transfer gain increased substantially with increasing frequency from 0.07 to 0.20 Hz in association with a gradual decrease in phase. The coherence function was > 0.5 in the frequency range of 0.07-0.30 Hz and < 0.5 at < 0.07 Hz. Furthermore, the predicted change in VMCA was similar to the measured VMCA during thigh cuff deflation. These data suggest that spontaneous changes in VMCA that occur at the frequency range of 0.07-0.30 Hz are related strongly to changes in arterial pressure and, furthermore, that short-term regulation of cerebral blood flow in response to changes in arterial pressure can be modeled by a transfer function with the quality of a high-pass filter in the frequency range of 0.07-0.30 Hz.
Comparison of geometrical and diffraction optical transfer functions
NASA Astrophysics Data System (ADS)
Mahajan, Virendra N.; Díaz, José Antonio
2015-09-01
The geometrical and diffraction point-spread functions of an optical imaging system have been reviewed and compared in the past [V. N. Mahajan, "Comparison of geometrical and diffraction point-spread functions," SPIE Proc. 3729, 434-445 (1999)]. In this paper, we review and compare its corresponding optical transfer functions. While the truth lies with the diffraction OTF, it is considered easier and quicker to calculate the geometrical OTF, especially for large aberrations. We briefly describe the theory of the two OTFs, and explore the range of spatial frequencies and the magnitude of the primary aberrations over which the geometrical OTF may provide a reasonable approximation of the diffraction OTF.
Subotnik, Joseph E.; Vura-Weis, Josh; Sodt, Alex J.; Ratner, Mark A.
2010-05-06
We model the triplet-triplet energy-transfer experiments from the Closs group [Closs, G. L.; et al. J. Am. Chem. Soc. 1988, 110, 2652.] using a combination of Marcus theory and either Boys or Edmiston-Ruedenberg localized diabatization, and we show that relative and absolute rates of electronic excitation transfer may be computed successfully. For the case where both the donor and acceptor occupy equatorial positions on a rigid cyclohexane bridge, we find β_{calc} = 2.8 per C-C bond, compared with the experimental value β_{exp} = 2.6. This work highlights the power of using localized diabatization methods as a tool for modeling nonequilibrium processes.
On the role of covarying functions in stimulus class formation and transfer of function.
Markham, Rebecca G; Markham, Michael R
2002-01-01
This experiment investigated whether directly trained covarying functions are necessary for stimulus class formation and transfer of function in humans. Initial class training was designed to establish two respondent-based stimulus classes by pairing two visual stimuli with shock and two other visual stimuli with no shock. Next, two operant discrimination functions were trained to one stimulus of each putative class. The no-shock group received the same training and testing in all phases, except no stimuli were ever paired with shock. The data indicated that skin conductance response conditioning did not occur for the shock groups or for the no-shock group. Tests showed transfer of the established discriminative functions, however, only for the shock groups, indicating the formation of two stimulus classes only for those participants who received respondent class training. The results suggest that transfer of function does not depend on first covarying the stimulus class functions. PMID:12507017
Matanovic, Ivana; Atanassov, Plamen; Kiefer, Boris; Garzon, Fernando; Henson, Neil J.
2014-10-05
The structural equilibrium parameters, the adsorption energies, and the vibrational frequencies of the nitrogen molecule and the hydrogen atom adsorbed on the (111) surface of rhodium have been investigated using different generalized-gradient approximation (GGA), nonlocal correlation, meta-GGA, and hybrid functionals, namely, Perdew, Burke, and Ernzerhof (PBE), Revised-RPBE, vdW-DF, Tao, Perdew, Staroverov, and Scuseria functional (TPSS), and Heyd, Scuseria, and Ernzerhof (HSE06) functional in the plane wave formalism. Among the five tested functionals, nonlocal vdW-DF and meta-GGA TPSS functionals are most successful in describing energetics of dinitrogen physisorption to the Rh(111) surface, while the PBE functional provides the correct chemisorption energy for the hydrogen atom. It was also found that TPSS functional produces the best vibrational spectra of the nitrogen molecule and the hydrogen atom on rhodium within the harmonic formalism with the error of 22.62 and 21.1% for the NAN stretching and RhAH stretching frequency. Thus, TPSS functional was proposed as a method of choice for obtaining vibrational spectra of low weight adsorbates on metallic surfaces within the harmonic approximation. At the anharmonic level, by decoupling the RhAH and NAN stretching modes from the bulk phonons and by solving one- and two-dimensional Schr€odinger equation associated with the RhAH, RhAN, and NAN potential energy we calculated the anharmonic correction for NAN and RhAH stretching modes as 231 cm21 and 277 cm21 at PBE level. Anharmonic vibrational frequencies calculated with the use of the hybrid HSE06 function are in best agreement with available experiments.
Matanović, Ivana; Atanassov, Plamen; Kiefer, Boris; Garzon, Fernando H; Henson, Neil J
2014-10-01
The structural equilibrium parameters, the adsorption energies, and the vibrational frequencies of the nitrogen molecule and the hydrogen atom adsorbed on the (111) surface of rhodium have been investigated using different generalized-gradient approximation (GGA), nonlocal correlation, meta-GGA, and hybrid functionals, namely, Perdew, Burke, and Ernzerhof (PBE), Revised-RPBE, vdW-DF, Tao, Perdew, Staroverov, and Scuseria functional (TPSS), and Heyd, Scuseria, and Ernzerhof (HSE06) functional in the plane wave formalism. Among the five tested functionals, nonlocal vdW-DF and meta-GGA TPSS functionals are most successful in describing energetics of dinitrogen physisorption to the Rh(111) surface, while the PBE functional provides the correct chemisorption energy for the hydrogen atom. It was also found that TPSS functional produces the best vibrational spectra of the nitrogen molecule and the hydrogen atom on rhodium within the harmonic formalism with the error of -2.62 and -1.1% for the N-N stretching and Rh-H stretching frequency. Thus, TPSS functional was proposed as a method of choice for obtaining vibrational spectra of low weight adsorbates on metallic surfaces within the harmonic approximation. At the anharmonic level, by decoupling the Rh-H and N-N stretching modes from the bulk phonons and by solving one- and two-dimensional Schrödinger equation associated with the Rh-H, Rh-N, and N-N potential energy we calculated the anharmonic correction for N-N and Rh-H stretching modes as -31 cm(-1) and -77 cm(-1) at PBE level. Anharmonic vibrational frequencies calculated with the use of the hybrid HSE06 function are in best agreement with available experiments. PMID:25164265
Measurement of the modulation transfer function of infrared cameras
NASA Astrophysics Data System (ADS)
Tzannes, Alexis P.; Mooney, Jonathan M.
1995-06-01
The performance of starting PtSi infrared cameras is characterized based on estimating their spatial frequency response. Applying a modified knife-edge technique, we arrive at an estimate of the edge spread function (ESF), which is used to obtain a profile through the center of the 2-D modulation transfer function (MTF). Using this technique, the complete system MTF in the horizontal and vertical direction is measured for various imaging systems. The influence of charge transfer efficiency (CTE) on the knife-edge measurement and resulting MTF is also modeled and discussed. An estimate of the CTE can actually be obtained from the shape of the ESF in the horizontal direction. In addition, we demonstrate that this technique can be used as a filed measurement. By applying the technique at long range, the MTF of the atmosphere can be measured.
Structural model updating using incomplete transfer function of strain data
NASA Astrophysics Data System (ADS)
Esfandiari, A.
2014-08-01
In this paper a model updating algorithm is presented to estimate structural parameters at the element level utilizing frequency domain representation of the strain data. Sensitivity equations for mass and stiffness parameters estimation are derived using decomposed form of the strain-based transfer functions. The rate of changes of eigenvectors and a subset of measured natural frequencies are used to assemble the sensitivity equation of the strain-based transfer function. Solution of the derived sensitivity equations through the least square method resulted in a robust parameters estimation method. Numerical examples using simulated noise polluted data of 2D truss and frame models confirm that the proposed method is able to successfully update structural models even in the presence of mass modeling errors.
Characterization of the modulation transfer function of discrete filtered backprojection.
Glick, S J; King, M A; Penney, B C
1989-01-01
A mathematical expression for the modulation transfer function (MTF) of image reconstruction by discrete filtered backprojection (DFBP) is derived. A simulation study is used to investigate the dependence of the MTF of DFBP on: (1) the number of projection views; (2) the type of ramp filter used; (3) the interpolation method used during backprojection; and (4) the position of the object. These results were compared to MTFs calculated from point-source single-photon-emission computed tomographic (SPECT) acquisitions in air. The experimentally obtained MTFs contained much of the same structure as the MTFs of DFBP obtained through simulation. It is shown that the discretization of the filtered backprojection process can cause the tomographic transfer function to be anisotropic and nonstationary. However, through proper selection of the methods used in reconstruction, a nearly isotropic and stationary MTF can be obtained. PMID:18230518
Properties of Zero-Free Transfer Function Matrices
NASA Astrophysics Data System (ADS)
D. O. Anderson, Brian; Deistler, Manfred
Transfer functions of linear, time-invariant finite-dimensional systems with more outputs than inputs, as arise in factor analysis (for example in econometrics), have, for state-variable descriptions with generic entries in the relevant matrices, no finite zeros. This paper gives a number of characterizations of such systems (and indeed square discrete-time systems with no zeros), using state-variable, impulse response, and matrix-fraction descriptions. Key properties include the ability to recover the input values at any time from a bounded interval of output values, without any knowledge of an initial state, and an ability to verify the no-zero property in terms of a property of the impulse response coefficient matrices. Results are particularized to cases where the transfer function matrix in question may or may not have a zero at infinity or a zero at zero.
Santiago, Régis Tadeu; Haiduke, Roberto Luiz Andrade
2015-10-30
This research provides a performance investigation of density functional theory and also proposes new functional parameterizations to deal with electric field gradient (EFG) calculations at nuclear positions. The entire procedure is conducted within the four-component formalism. First, we noticed that traditional hybrid and long-range corrected functionals are more efficient in the description of EFG variations for a set of elements (indium, antimony, iodine, lutetium, and hafnium) among linear molecules. Thus, we selected the PBE0, B3LYP, and CAM-B3LYP functionals and promoted a reoptimization of their parameters for a better description of these EFG changes. The PBE0q variant developed here showed an overall promising performance in a validation test conducted with potassium, iodine, copper, and gold. In general, the correlation coefficients found in linear regressions between experimental nuclear quadrupole coupling constants and calculated EFGs are improved while the systematic EFG errors also decrease as a result of this reparameterization. PMID:26284820
Return of lymphatic function after flap transfer for acute lymphedema.
Slavin, S A; Van den Abbeele, A D; Losken, A; Swartz, M A; Jain, R K
1999-01-01
OBJECTIVE: The goals of this work were to develop animal models of lymphedema and tissue flap transfer, and to observe physiologic changes in lymphatic function that occur in these models over time, both systemically with lymphoscintigraphy (LS) and locally using fluorescence microlymphangiography (FM). SUMMARY BACKGROUND DATA: Although lymphedema has been managed by a combination of medical and surgical approaches, no effective long-term cure exists. Surgical attempts aimed at reconnecting impaired lymphatic channels or bypassing obstructed areas have failed. METHODS: The tails of rats (A groups) and mice (B groups) were used because of their different features. Lymphedema was created by ligation of the lymphatics at the tail base and quantified by diameter measurements there. In the experimental group, rectus abdominis myocutaneous flap was transferred across the ligation. In addition to the ligation (A1 and B1) and ligation + flap (A2 and B2) groups, three control groups were included: sham flap with ligation (B4), sham flap alone (B5), and normal (A3 and B3) animals. Observations were made at weekly time points for lymphatic function and continuity. RESULTS: Lymphedema was successfully created in the mouse ligation groups (B1 and B4) and sustained for the entire length of observation (up to 14 weeks). Lymphatic continuity was restored in those animals with transferred flaps across the ligation site (A2 and B2), as seen both by LS and FM. Sham flaps did not visibly affect lymphatic function nor did they cause any visible swelling in the tail. CONCLUSIONS: Acute lymphedema developing after ligation of tail lymphatics in mice can be prevented by myocutaneous flap transfer. Restored lymphatic continuity and function were demonstrable using lymphoscintigraphy and fluorescence microlymphangiography. Images Figure 2. Figure 4. Figure 5. PMID:10077056
A Derived Transfer of Mood Functions through Equivalence Relations
ERIC Educational Resources Information Center
Barnes-Holmes, Yvonne; Barnes-Holmes, Dermot; Smeets, Paul M.; Luciano, Carmen
2004-01-01
The present study investigated the transfer of induced happy and sad mood functions through equivalence relations. Sixteen subjects participated in a combined equivalence and mood induction procedure. In Phase 1, all subjects were trained in 2 conditional discriminations using a matching-to-sample format (i.e., A1-B1, A2-B2, A1-C1, A2-C2). In…
Determination of the electronics transfer function for current transient measurements
NASA Astrophysics Data System (ADS)
Scharf, Christian; Klanner, Robert
2015-04-01
We describe a straight-forward method for determining the transfer function of the readout of a sensor for the situation in which the current transient of the sensor can be precisely simulated. The method relies on the convolution theorem of Fourier transforms. The specific example is a planar silicon pad diode. The charge carriers in the sensor are produced by picosecond lasers with light of wavelengths of 675 and 1060 nm. The transfer function is determined from the 1060 nm data with the pad diode biased at 1000 V. It is shown that the simulated sensor response convoluted with this transfer function provides an excellent description of the measured transients for laser light of both wavelengths. The method has been applied successfully for the simulation of current transients of several different silicon pad diodes. It can also be applied for the analysis of transient-current measurements of radiation-damaged solid state sensors, as long as sensors properties, like high-frequency capacitance, are not too different.
Photothermal transfer function of dielectric mirrors for precision measurements
NASA Astrophysics Data System (ADS)
Ballmer, Stefan W.
2015-01-01
The photothermal transfer function from absorbed power incident on a dielectric mirror to the effective mirror position is calculated using the coating design as input. The effect is found to change in amplitude and sign for frequencies corresponding to diffusion length comparable to the coating thickness. Transfer functions are calculated for the T i -doped Ta2O5:SiO2 coating used in Advanced LIGO and for a crystalline AlxGa1 -xAs coating. The shape of the transfer function at high frequencies is shown to be a sensitive indicator of the effective absorption depth, providing a potentially powerful tool to distinguish coating-internal absorption from surface contamination related absorption. The sign change of the photothermal effect could also be useful to stabilize radiation pressure-based optomechanical systems. High frequency corrections to the previously published thermo-optic noise estimates are also provided. Finally, estimating the quality of the thermo-optic noise cancellation occurring in fine-tuned AlxGa1 -xAs coatings requires the detailed heat flow analysis done in this paper.
Boundary emphasis transfer function generation based on HSL color space
NASA Astrophysics Data System (ADS)
Li, Xiao; Wu, Jianhuang; Luo, Shengzhou; Ma, Xin
2011-10-01
Direct volume rendering has been received much attention since it need not to extract geometric primitives for visualization and its performance is generally better than surface rendering. Transfer functions, which are used for mapping scalar field to optical properties, are of vital importance in obtaining a sensible rendering result from volume data. Though traditional color transfer functions are in RGB color space, HSL color space that conveys semantic meanings is more intuitive and user-friendly. In this paper, we present a novel approach aims to emphasize and distinguish strong boundaries between different materials. We achieve it by using data value, gradient magnitude and dimension of the volumetric data to set opacity. Then, through a linear map from data value, gradient magnitude and second derivative to hue, saturation and lightness respectively, a color transfer function is obtained in HSL color space. Experimental tests on real-world datasets indicate that our method could achieve desirable rendering results with revealing important boundaries between different structures and indicating data value's distribution in the volume by using different colors.
Data formats for a library of Kerr metric transfer functions
NASA Astrophysics Data System (ADS)
McDowell, Jonathan C.; Brenneman, Laura; Reynolds, Christopher S.; Keck, Mason; Risaliti, Guido
2015-01-01
As part of a project to model time-resolved X-ray obscuration in AGN, we have reimplemented and improved the Reynolds et al (1999, ApJ 514, 164) approach to calculating the transfer functions which give the redshift and projected orientation of an accretion disk element in the observer frame. We define a multi-extension FITS image array format which contains the computed transfer function for a given value of observation angle and black hole spin parameter. Each extension contains an image, in observer plane coordinates, of a different physical quantity: redshift, direction cosine, geodesic coordinates, etc. This allows us to build up a library of transfer function files for different observation angles, each with moderate (less than 200 Mbyte) storage requirements. Use of the FITS format allows us to record the associated model parameters and coordinate systems in a standard way and to visualize the results using standard analysis tools such as ds9. We illustrate preliminary spectral modelling results obtained using this approach.
Transfer Function Identification of an Electro-Rheological Actuator
NASA Astrophysics Data System (ADS)
Brookfield, D. J.; Dlodlo, Z. B.
A fluid clutch utilising an Electro-Rheological (ER) suspension provides a controlled torque coupling between input and output through the control of the applied electric field. If the input is driven at constant speed the device can be considered as an ER torque actuator and thus be used to drive robot links or other mechanisms requiring precise positioning. Such an ER torque actuator can replace a DC servo-motor in robotic applications with the benefits of low time constant and smooth output torque unaffected by cogging (i.e. variation in torque of a DC motor as the magnetic reluctance of the armature-stator path changes with rotation). Although the ER actuator has many benefits, it suffers from a non-linear and time varying relationship between input voltage and output torque. These undesirable characteristics can be mitigated by providing a local closed loop controller around the system. The design of such a controller requires a knowledge of the relationship between the applied voltage and output torque; i.e. the transfer function of the actuator. This transfer function has been determined by observing the response of an ER torque actuator in the frequency domain. It is shown that a linear transfer function model reasonable represents the actuator behaviour, that the actuator is a stable second order system and that the time constant of the clutch studied is sufficiently short to hold considerable promise for robotic applications. Furthermore, the maximum torque capability is shown to be sufficient for many medium scale industrial robots.
Accurate and efficient calculation of discrete correlation functions and power spectra
NASA Astrophysics Data System (ADS)
Xu, Y. F.; Liu, J. M.; Zhu, W. D.
2015-07-01
Operational modal analysis (OMA), or output-only modal analysis, has been widely conducted especially when excitation applied on a structure is unknown or difficult to measure. Discrete cross-correlation functions and cross-power spectra between a reference data series and measured response data series are bases for OMA to identify modal properties of a structure. Such functions and spectra can be efficiently transformed from each other using the discrete Fourier transform (DFT) and inverse DFT (IDFT) based on the cross-correlation theorem. However, a direct application of the theorem and transforms, including the DFT and IDFT, can yield physically erroneous results due to periodic extension of the DFT on a function of a finite length to be transformed, which is false most of the time. Padding zero series to ends of data series before applying the theorem and transforms can reduce the errors, but the results are still physically erroneous. A new methodology is developed in this work to calculate discrete cross-correlation functions of non-negative time delays and associated cross-power spectra, referred to as half spectra, for OMA. The methodology can be extended to cross-correlation functions of any time delays and associated cross-power spectra, referred to as full spectra. The new methodology is computationally efficient due to use of the transforms. Data series are properly processed to avoid the errors caused by the periodic extension, and the resulting cross-correlation functions and associated cross-power spectra perfectly comply with their definitions. A coherence function, a convergence function, and a convergence index are introduced to evaluate qualities of measured cross-correlation functions and associated cross-power spectra. The new methodology was numerically and experimentally applied to an ideal two-degree-of-freedom (2-DOF) mass-spring-damper system and a damaged aluminum beam, respectively, and OMA was conducted using half spectra to estimate
Zaki, S.K.; Bretan, P.N.; Go, R.T.; Rehm, P.K.; Streem, S.B.; Novick, A.C. )
1990-06-01
Orthoiodohippurate renal scanning has proved to be a reliable, noninvasive method for the evaluation and followup of renal allograft function. However, a standardized system for grading renal function with this test is not available. We propose a simple grading system to distinguish the different functional phases of hippurate scanning in renal transplant recipients. This grading system was studied in 138 patients who were evaluated 1 week after renal transplantation. There was a significant correlation between the isotope renographic functional grade and clinical correlates of allograft function such as the serum creatinine level (p = 0.0001), blood urea nitrogen level (p = 0.0001), urine output (p = 0.005) and need for hemodialysis (p = 0.007). We recommend this grading system as a simple and accurate method to interpret orthoiodohippurate renal scans in the evaluation and followup of renal allograft recipients.
Modulation transfer function measurement technique for small-pixel detectors
NASA Technical Reports Server (NTRS)
Marchywka, Mike; Socker, Dennis G.
1992-01-01
A modulation transfer function (MTF) measurement technique suitable for large-format, small-pixel detector characterization has been investigated. A volume interference grating is used as a test image instead of the bar or sine wave target images normally used. This technique permits a high-contrast, large-area, sinusoidal intensity distribution to illuminate the device being tested, avoiding the need to deconvolve raw data with imaging system characteristics. A high-confidence MTF result at spatial frequencies near 200 cycles/mm is obtained. We present results at several visible light wavelengths with a 6.8-micron-pixel CCD. Pixel response functions are derived from the MTF results.
An extended set of yeast-based functional assays accurately identifies human disease mutations.
Sun, Song; Yang, Fan; Tan, Guihong; Costanzo, Michael; Oughtred, Rose; Hirschman, Jodi; Theesfeld, Chandra L; Bansal, Pritpal; Sahni, Nidhi; Yi, Song; Yu, Analyn; Tyagi, Tanya; Tie, Cathy; Hill, David E; Vidal, Marc; Andrews, Brenda J; Boone, Charles; Dolinski, Kara; Roth, Frederick P
2016-05-01
We can now routinely identify coding variants within individual human genomes. A pressing challenge is to determine which variants disrupt the function of disease-associated genes. Both experimental and computational methods exist to predict pathogenicity of human genetic variation. However, a systematic performance comparison between them has been lacking. Therefore, we developed and exploited a panel of 26 yeast-based functional complementation assays to measure the impact of 179 variants (101 disease- and 78 non-disease-associated variants) from 22 human disease genes. Using the resulting reference standard, we show that experimental functional assays in a 1-billion-year diverged model organism can identify pathogenic alleles with significantly higher precision and specificity than current computational methods. PMID:26975778
An extended set of yeast-based functional assays accurately identifies human disease mutations
Sun, Song; Yang, Fan; Tan, Guihong; Costanzo, Michael; Oughtred, Rose; Hirschman, Jodi; Theesfeld, Chandra L.; Bansal, Pritpal; Sahni, Nidhi; Yi, Song; Yu, Analyn; Tyagi, Tanya; Tie, Cathy; Hill, David E.; Vidal, Marc; Andrews, Brenda J.; Boone, Charles; Dolinski, Kara; Roth, Frederick P.
2016-01-01
We can now routinely identify coding variants within individual human genomes. A pressing challenge is to determine which variants disrupt the function of disease-associated genes. Both experimental and computational methods exist to predict pathogenicity of human genetic variation. However, a systematic performance comparison between them has been lacking. Therefore, we developed and exploited a panel of 26 yeast-based functional complementation assays to measure the impact of 179 variants (101 disease- and 78 non-disease-associated variants) from 22 human disease genes. Using the resulting reference standard, we show that experimental functional assays in a 1-billion-year diverged model organism can identify pathogenic alleles with significantly higher precision and specificity than current computational methods. PMID:26975778
Calbo, Joaquín; Ortí, Enrique; Sancho-García, Juan C; Aragó, Juan
2015-03-10
In this work, we present a thorough assessment of the performance of some representative double-hybrid density functionals (revPBE0-DH-NL and B2PLYP-NL) as well as their parent hybrid and GGA counterparts, in combination with the most modern version of the nonlocal (NL) van der Waals correction to describe very large weakly interacting molecular systems dominated by noncovalent interactions. Prior to the assessment, an accurate and homogeneous set of reference interaction energies was computed for the supramolecular complexes constituting the L7 and S12L data sets by using the novel, precise, and efficient DLPNO-CCSD(T) method at the complete basis set limit (CBS). The correction of the basis set superposition error and the inclusion of the deformation energies (for the S12L set) have been crucial for obtaining precise DLPNO-CCSD(T)/CBS interaction energies. Among the density functionals evaluated, the double-hybrid revPBE0-DH-NL and B2PLYP-NL with the three-body dispersion correction provide remarkably accurate association energies very close to the chemical accuracy. Overall, the NL van der Waals approach combined with proper density functionals can be seen as an accurate and affordable computational tool for the modeling of large weakly bonded supramolecular systems. PMID:26579747
Abdelnour, Farras; Voss, Henning U.; Raj, Ashish
2014-01-01
The relationship between anatomic connectivity of large-scale brain networks and their functional connectivity is of immense importance and an area of active research. Previous attempts have required complex simulations which model the dynamics of each cortical region, and explore the coupling between regions as derived by anatomic connections. While much insight is gained from these non-linear simulations, they can be computationally taxing tools for predicting functional from anatomic connectivities. Little attention has been paid to linear models. Here we show that a properly designed linear model appears to be superior to previous non-linear approaches in capturing the brain’s long-range second order correlation structure that governs the relationship between anatomic and functional connectivities. We derive a linear network of brain dynamics based on graph diffusion, whereby the diffusing quantity undergoes a random walk on a graph. We test our model using subjects who underwent diffusion MRI and resting state fMRI. The network diffusion model applied to the structural networks largely predicts the correlation structures derived from their fMRI data, to a greater extent than other approaches. The utility of the proposed approach is that it can routinely be used to infer functional correlation from anatomic connectivity. And since it is linear, anatomic connectivity can also be inferred from functional data. The success of our model confirms the linearity of ensemble average signals in the brain, and implies that their long-range correlation structure may percolate within the brain via purely mechanistic processes enacted on its structural connectivity pathways. PMID:24384152
Density functional theory for protein transfer free energy.
Mills, Eric A; Plotkin, Steven S
2013-10-24
We cast the problem of protein transfer free energy within the formalism of density functional theory (DFT), treating the protein as a source of external potential that acts upon the solvent. Solvent excluded volume, solvent-accessible surface area, and temperature dependence of the transfer free energy all emerge naturally within this formalism, and may be compared with simplified "back of the envelope" models, which are also developed here. Depletion contributions to osmolyte induced stability range from 5 to 10 kBT for typical protein lengths. The general DFT transfer theory developed here may be simplified to reproduce a Langmuir isotherm condensation mechanism on the protein surface in the limits of short-ranged interactions, and dilute solute. Extending the equation of state to higher solute densities results in non-monotonic behavior of the free energy driving protein or polymer collapse. Effective interaction potentials between protein backbone or side chains and TMAO are obtained, assuming a simple backbone/side chain two-bead model for the protein with an effective 6-12 potential with the osmolyte. The transfer free energy δg shows significant entropy: d(δg)/dT ≈ 20 kB for a 100-residue protein. The application of DFT to effective solvent forces for use in implicit-solvent molecular dynamics is also developed. The simplest DFT expressions for implicit-solvent forces contain both depletion interactions and an "impeded-solvation" repulsive force at larger distances. PMID:23944753
NASA Astrophysics Data System (ADS)
Lee, Dong-Hoon; Kim, Ye-seul; Park, Hye-Suk; Lee, Young-Jin; Kim, Hee-Joung
2015-03-01
Image evaluation is necessary in digital radiography (DR) which is widely used in medical imaging. Among parameters of image evaluation, modulation transfer function (MTF) is the important factor in the field of medical imaging and necessary to obtain detective quantum efficiency (DQE) which represents overall performance of the detector signal-to-noise ratio. However, the accurate measurement of MTF is still not easy because of geometric effect, electric noise, quantum noise, and truncation error. Therefore, in order to improve accuracy of MTF, four experimental methods were tested in this study such as changing the tube current, applying smoothing method in edge spread function (ESF), adjusting line spread function (LSF) range, and changing tube angle. Our results showed that MTF's fluctuation was decreased by high tube current and smoothing method. However, tube current should not exceed detector saturation and smoothing in ESF causes a distortion in ESF and MTF. In addition, decreasing LSF range diminished fluctuation and the number of sampling in MTF and high tube angle generates degradation in MTF. Based on these results, excessively low tube current and the smoothing method should be avoided. Also, optimal range of LSF considering reduction of fluctuation and the number of sampling in MTF was necessary and precise tube angle is essential to obtain an accurate MTF. In conclusion, our results demonstrated that accurate MTF can be acquired.
A method for the accurate and smooth approximation of standard thermodynamic functions
NASA Astrophysics Data System (ADS)
Coufal, O.
2013-01-01
A method is proposed for the calculation of approximations of standard thermodynamic functions. The method is consistent with the physical properties of standard thermodynamic functions. This means that the approximation functions are, in contrast to the hitherto used approximations, continuous and smooth in every temperature interval in which no phase transformations take place. The calculation algorithm was implemented by the SmoothSTF program in the C++ language which is part of this paper. Program summaryProgram title:SmoothSTF Catalogue identifier: AENH_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENH_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 3807 No. of bytes in distributed program, including test data, etc.: 131965 Distribution format: tar.gz Programming language: C++. Computer: Any computer with gcc version 4.3.2 compiler. Operating system: Debian GNU Linux 6.0. The program can be run in operating systems in which the gcc compiler can be installed, see http://gcc.gnu.org/install/specific.html. RAM: 256 MB are sufficient for the table of standard thermodynamic functions with 500 lines Classification: 4.9. Nature of problem: Standard thermodynamic functions (STF) of individual substances are given by thermal capacity at constant pressure, entropy and enthalpy. STF are continuous and smooth in every temperature interval in which no phase transformations take place. The temperature dependence of STF as expressed by the table of its values is for further application approximated by temperature functions. In the paper, a method is proposed for calculating approximation functions which, in contrast to the hitherto used approximations, are continuous and smooth in every temperature interval. Solution method: The approximation functions are
NASA Astrophysics Data System (ADS)
Balabin, Roman M.; Lomakina, Ekaterina I.
2009-08-01
Artificial neural network (ANN) approach has been applied to estimate the density functional theory (DFT) energy with large basis set using lower-level energy values and molecular descriptors. A total of 208 different molecules were used for the ANN training, cross validation, and testing by applying BLYP, B3LYP, and BMK density functionals. Hartree-Fock results were reported for comparison. Furthermore, constitutional molecular descriptor (CD) and quantum-chemical molecular descriptor (QD) were used for building the calibration model. The neural network structure optimization, leading to four to five hidden neurons, was also carried out. The usage of several low-level energy values was found to greatly reduce the prediction error. An expected error, mean absolute deviation, for ANN approximation to DFT energies was 0.6±0.2 kcal mol-1. In addition, the comparison of the different density functionals with the basis sets and the comparison of multiple linear regression results were also provided. The CDs were found to overcome limitation of the QD. Furthermore, the effective ANN model for DFT/6-311G(3df,3pd) and DFT/6-311G(2df,2pd) energy estimation was developed, and the benchmark results were provided.
Li, Jin; Xing, Fei; Sun, Ting; You, Zheng
2015-03-01
Modulation transfer function (MTF) can be used to evaluate the imaging performance of on-board optical remote sensing sensors, as well as recover and restore images to improve imaging quality. Laboratory measurement approaches for MTF have achieved high precision. However, they are not yet suitable for on-board measurement. In this paper, a new five-step approach to calculate MTF of space optical remote sensing sensors is proposed. First, a pixel motion model is used to extract the conditional sub-frame images. Second, a mathematical morphology algorithm and a correlation-homomorphic filter algorithm are used to eliminate noise and enhance sub-frame image. Third, an image partial differentiation determines the accurate position of edge points. Fourth, a model optical function is used to build a high-resolution edge spread function. Finally, MTF is calculated by derivation and Fourier transform. The experiment shows that the assessment method of MTF is superior to others. PMID:25836841
NASA Astrophysics Data System (ADS)
Małolepsza, Edyta; Witek, Henryk A.; Morokuma, Keiji
2005-09-01
An optimization technique for enhancing the quality of repulsive two-body potentials of the self-consistent-charge density-functional tight-binding (SCC-DFTB) method is presented and tested. The new, optimized potentials allow for significant improvement of calculated harmonic vibrational frequencies. Mean absolute deviation from experiment computed for a group of 14 hydrocarbons is reduced from 59.0 to 33.2 cm -1 and maximal absolute deviation, from 436.2 to 140.4 cm -1. A drawback of the new family of potentials is a lower quality of reproduced geometrical and energetic parameters.
Modulation transfer function technique for real time radioscopic system characterization
Tobin, K.W. ); Brenizer, J.S. ); Mait, J.N. )
1989-12-01
At the University of Virginia neutron radiography facility, a modulation transfer function technique has been developed that can easily predict and compare the resolving characteristics of the real time system and the individual system components. We desired a simple method by which new system components could be analyzed to determine their image transfer characteristics and to estimate how they would affect the composite system during data acquisition. The method employed measures a small set of constant system parameters related to data collected across a cadmium cut-edge aperture. The effects of system noise and spatial variance on the measured data are reduced so that a representation of the true signal can be obtained for analysis. Resolution parameters for the total neutron radiography system and for the individual system components are reported.
Modulation transfer function technique for real time radioscopic system characterization.
Tobin, K W; Brenizer, J S; Mait, J N
1989-12-01
At the University of Virginia neutron radiography facility, a modulation transfer function technique has been developed that can easily predict and compare the resolving characteristics of the real time system and the individual system components. We desired a simple method by which new system components could be analyzed to determine their image transfer characteristics and to estimate how they would affect the composite system during data acquisition. The method employed measures a small set of constant system parameters related to data collected across a cadmium cut-edge aperture. The effects of system noise and spatial variance on the measured data are reduced so that a representation of the true signal can be obtained for analysis. Resolution parameters for the total neutron radiography system and for the individual system components are reported. PMID:20555991
Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
Zhang, Gang; Mendez, Blanca Lopez; Sedgwick, Garry G.; Nilsson, Jakob
2016-01-01
The BubR1/Bub3 complex is an important regulator of chromosome segregation as it facilitates proper kinetochore–microtubule interactions and is also an essential component of the spindle assembly checkpoint (SAC). Whether BubR1/Bub3 localization to kinetochores in human cells stimulates SAC signalling or only contributes to kinetochore–microtubule interactions is debated. Here we show that two distinct pools of BubR1/Bub3 exist at kinetochores and we uncouple these with defined BubR1/Bub3 mutants to address their function. The major kinetochore pool of BubR1/Bub3 is dependent on direct Bub1/Bub3 binding and is required for chromosome alignment but not for the SAC. A distinct pool of BubR1/Bub3 localizes by directly binding to phosphorylated MELT repeats on the outer kinetochore protein KNL1. When we prevent the direct binding of BubR1/Bub3 to KNL1 the checkpoint is weakened because BubR1/Bub3 is not incorporated into checkpoint complexes efficiently. In conclusion, kinetochore localization supports both known functions of BubR1/Bub3. PMID:27457023
Chon, K H; Cohen, R J; Holstein-Rathlou, N H
1997-01-01
A linear and nonlinear autoregressive moving average (ARMA) identification algorithm is developed for modeling time series data. The algorithm uses Laguerre expansion of kernals (LEK) to estimate Volterra-Wiener kernals. However, instead of estimating linear and nonlinear system dynamics via moving average models, as is the case for the Volterra-Wiener analysis, we propose an ARMA model-based approach. The proposed algorithm is essentially the same as LEK, but this algorithm is extended to include past values of the output as well. Thus, all of the advantages associated with using the Laguerre function remain with our algorithm; but, by extending the algorithm to the linear and nonlinear ARMA model, a significant reduction in the number of Laguerre functions can be made, compared with the Volterra-Wiener approach. This translates into a more compact system representation and makes the physiological interpretation of higher order kernels easier. Furthermore, simulation results show better performance of the proposed approach in estimating the system dynamics than LEK in certain cases, and it remains effective in the presence of significant additive measurement noise. PMID:9236985
NASA Astrophysics Data System (ADS)
Teipen, Brian Thomas
2000-12-01
Over the years, several optical and opto-electronic systems have been invented in order to reproduce or improve an ability to image a physical scene. Optical imaging (vision) delivers the capability to collect an enormous amount of information about the surrounding environment. The quality of any imaging system can be conveniently defined by the amount of information that is ultimately gathered. Information transfer is the fundamental process of imaging systems and often can be described in terms of linear systems. Conveniently, transfer functions common to linear systems theory (communications theory) can be adopted to accurately describe optical information transfer in imaging systems. In this dissertation, we report on the advancements of two areas of optical imaging. Firstly, we present a new measurement process involving pseudo-random spatial patterns generated with a liquid crystal display (LCD) that allows convenient determination of the spatial- frequency transfer function commonly known as the modulation transfer function (MTF) of digital imaging systems. We present horizontal and vertical MTF measurements for color and monochrome charge-coupled device (CCD) video systems, common to machine vision and robotic vision applications. Results are found to agree with previously applied methods of measuring imaging resolution, while increasing the speed, adaptability, and convenience of the measurement. Secondly, we present three-dimensional (3-D) shape measurements from a new experimental method using polarization-encoded spatial patterns. The measurement technique is an active method of vision using projected patterns from a LCD projector. Part of the polarization-encoded pattern, a sub-pattern that is a pseudo-random code, is dedicated to solve the difficult problem of measuring the absolute height of an object with edge discontinuities. This technique conveniently allows lost fringe-order information of the classic synthetic-fringe pattern to be regained.
Shen, Yan; Lou, Shuqin; Wang, Xin
2014-03-20
The evaluation accuracy of real optical properties of photonic crystal fibers (PCFs) is determined by the accurate extraction of air hole edges from microscope images of cross sections of practical PCFs. A novel estimation method of point spread function (PSF) based on Kalman filter is presented to rebuild the micrograph image of the PCF cross-section and thus evaluate real optical properties for practical PCFs. Through tests on both artificially degraded images and microscope images of cross sections of practical PCFs, we prove that the proposed method can achieve more accurate PSF estimation and lower PSF variance than the traditional Bayesian estimation method, and thus also reduce the defocus effect. With this method, we rebuild the microscope images of two kinds of commercial PCFs produced by Crystal Fiber and analyze the real optical properties of these PCFs. Numerical results are in accord with the product parameters. PMID:24663461
NASA Astrophysics Data System (ADS)
Trujillo Bueno, J.; Fabiani Bendicho, P.
1995-12-01
Iterative schemes based on Gauss-Seidel (G-S) and optimal successive over-relaxation (SOR) iteration are shown to provide a dramatic increase in the speed with which non-LTE radiation transfer (RT) problems can be solved. The convergence rates of these new RT methods are identical to those of upper triangular nonlocal approximate operator splitting techniques, but the computing time per iteration and the memory requirements are similar to those of a local operator splitting method. In addition to these properties, both methods are particularly suitable for multidimensional geometry, since they neither require the actual construction of nonlocal approximate operators nor the application of any matrix inversion procedure. Compared with the currently used Jacobi technique, which is based on the optimal local approximate operator (see Olson, Auer, & Buchler 1986), the G-S method presented here is faster by a factor 2. It gives excellent smoothing of the high-frequency error components, which makes it the iterative scheme of choice for multigrid radiative transfer. This G-S method can also be suitably combined with standard acceleration techniques to achieve even higher performance. Although the convergence rate of the optimal SOR scheme developed here for solving non-LTE RT problems is much higher than G-S, the computing time per iteration is also minimal, i.e., virtually identical to that of a local operator splitting method. While the conventional optimal local operator scheme provides the converged solution after a total CPU time (measured in arbitrary units) approximately equal to the number n of points per decade of optical depth, the time needed by this new method based on the optimal SOR iterations is only √n/2√2. This method is competitive with those that result from combining the above-mentioned Jacobi and G-S schemes with the best acceleration techniques. Contrary to what happens with the local operator splitting strategy currently in use, these novel
X-ray modulation transfer functions of photostimulable phosphor image plates and scanners
Seely, John F.; Holland, Glenn E.; Hudson, Lawrence T.; Henins, Albert
2008-11-01
The modulation transfer functions of two types of photostimulable phosphor image plates were determined in the 10 keV to 50 keV x-ray energy range using a resolution test pattern with up to 10 line pairs per mm (LP/mm) and a wavelength dispersive x-ray spectrometer. Techniques were developed for correcting for the partial transmittance of the high energy x rays through the lead bars of the resolution test pattern, and the modulation transfer function (MTF) was determined from the measured change in contrast with LP/mm values. The MTF was convolved with the slit function of the image plate scanner, and the resulting point spread functions (PSFs) were in good agreement with the observed shapes and widths of x-ray spectral lines and with the PSF derived from edge spread functions. The shapes and the full width at half-maximum (FWHM) values of the PSF curves of the Fuji Superior Resolution (SR) and Fuji Maximum Sensitivity (MS) image plate detectors, consisting of the image plate and the scanner, determined by the three methods gave consistent results: The SR PSF is Gaussian with 0.13 mm FWHM, and the MS PSF is Lorentzian with 0.19 mm FWHM. These techniques result in the accurate determination of the spatial resolution achievable using image plate and scanner combinations and enable the optimization of spatial resolution for x-ray spectroscopy and radiography.
Accurate hydrogen bond energies within the density functional tight binding method.
Domínguez, A; Niehaus, T A; Frauenheim, T
2015-04-01
The density-functional-based tight-binding (DFTB) approach has been recently extended by incorporating one-center exchange-like terms in the expansion of the multicenter integrals. This goes beyond the Mulliken approximation and leads to a scheme which treats in a self-consistent way the fluctuations of the whole dual density matrix and not only its diagonal elements (Mulliken charges). To date, only the performance of this new formalism to reproduce excited-state properties has been assessed (Domínguez et al. J. Chem. Theory Comput., 2013, 9, 4901-4914). Here we study the effect of our corrections on the computation of hydrogen bond energies for water clusters and water-containing systems. The limitations of traditional DFTB to reproduce hydrogen bonds has been acknowledged often. We compare our results for a set of 22 small water clusters and water-containing systems as well as for five water hexadecamers to those obtained with the DFTB3 method. Additionally, we combine our extension with a third-order energy expansion in the charge fluctuations. Our results show that the new formalisms significantly improve upon original DFTB. PMID:25763597
Jiang, Bin; Guo, Hua
2016-08-01
In search for an accurate description of the dissociative chemisorption of water on the Ni(111) surface, we report a new nine-dimensional potential energy surface (PES) based on a large number of density functional theory points using the RPBE functional. Seven-dimensional quantum dynamical calculations have been carried out on the RPBE PES, followed by site averaging and lattice effect corrections, yielding sticking probabilities that are compared with both the previous theoretical results based on a PW91 PES and experiment. It is shown that the RPBE functional increases the reaction barrier, but has otherwise a minor impact on the PES topography. Better agreement with experimental results is obtained with the new PES, but the agreement is still not quantitative. Possible sources of the remaining discrepancies are discussed. PMID:27436348
On identifying transfer functions and state equations for linear systems.
NASA Technical Reports Server (NTRS)
Shieh, L. S.; Chen, C. F.; Huang, C. J.
1972-01-01
Two methods are established for identifying constant-coefficient, C to the 2n power type of noise-free linear systems if the time response data of the input-output or of all states are known. 2n response data are required to identify an nth-order transfer function or state equation for an unknown linear system. The order of the unknown system can be identified by checking a sequence of determinants. The Z transform and its inversion are mainly used.
Modulation transfer function of a trapezoidal pixel array detector
NASA Astrophysics Data System (ADS)
Wang, Fan; Guo, Rongli; Ni, Jinping; Dong, Tao
2016-01-01
The modulation transfer function (MTF) is the tool most commonly used for quantifying the performance of an electro-optical imaging system. Recently, trapezoid-shaped pixels were designed and used in a retina-like sensor in place of rectangular-shaped pixels. The MTF of a detector with a trapezoidal pixel array is determined according to its definition. Additionally, the MTFs of detectors with differently shaped pixels, but the same pixel areas, are compared. The results show that the MTF values of the trapezoidal pixel array detector are obviously larger than those of rectangular and triangular pixel array detectors at the same frequencies.
Two-dimensional modulation transfer function: a new perspective.
Marom, Emanuel; Milgrom, Benjamin; Konforti, Naim
2010-12-10
One-dimensional templates, such as the U.S. Air Force resolution target or the circular spoke target, are commonly used for the characterization of imaging systems via the modulation transfer function response. It is shown in this paper that one needs a new family of templates for a true characterization of imaging systems that acquire two-dimensional (2D) high-density images or handle 2D information, such as 2D bar code detection and identification. The contrast provided by the newly defined 2D templates is the "true" contrast of the acquired image that the electronic processors are challenged with. PMID:21151231
Two-dimensional modulation transfer functions of image scanning systems.
Simonds, R M
1981-02-15
Image data processing based on optical scanning and digital reconstruction frequently ignores artifacts produced by the scanning process itself. Characterization of these artifacts by measurement of system modulation transfer function (MTF) using the traditional knife-edge scan technique produces only one section of the 2-D MTF, and interpretation of this as representative of the complete MTF may yield misleading re A theoretical analysis is presented which allows reconstruction of the complete 2-D MTF from a sequence of knife-edge measurements, and an experimental example is shown for the case of a vidicon camera based scanning system. PMID:20309166
Modulation transfer function measurement technique for image sensor arrays
NASA Astrophysics Data System (ADS)
Jin, Hui; Jiang, Huilin; Zhang, XiaoHui
2010-08-01
A new technique is demonstrated for measurement of modulation transfer function (MTF) on image sensor arrays. Fourier analysis of a low frequency bar target pattern is used to extract MTF at odd harmonics of a target pattern frequency up to and beyond Nyquist. The technique is particularly useful for linear image arrays (either conventional linescan or time-delay- integration devices) where conventional slanted-edge technique is not always applicable. The technique is well suited to simple implementation and can provide live presentation of the MTF curve, which helps to ensure optimal alignment conditions are achieved. Detailed analysis of the technique and demonstration of experimental results are presented.
Transfer function modeling of damping mechanisms in distributed parameter models
NASA Technical Reports Server (NTRS)
Slater, J. C.; Inman, D. J.
1994-01-01
This work formulates a method for the modeling of material damping characteristics in distributed parameter models which may be easily applied to models such as rod, plate, and beam equations. The general linear boundary value vibration equation is modified to incorporate hysteresis effects represented by complex stiffness using the transfer function approach proposed by Golla and Hughes. The governing characteristic equations are decoupled through separation of variables yielding solutions similar to those of undamped classical theory, allowing solution of the steady state as well as transient response. Example problems and solutions are provided demonstrating the similarity of the solutions to those of the classical theories and transient responses of nonviscous systems.
Analysis of diagnostic calorimeter data by the transfer function technique
NASA Astrophysics Data System (ADS)
Delogu, R. S.; Poggi, C.; Pimazzoni, A.; Rossi, G.; Serianni, G.
2016-02-01
This paper describes the analysis procedure applied to the thermal measurements on the rear side of a carbon fibre composite calorimeter with the purpose of reconstructing the energy flux due to an ion beam colliding on the front side. The method is based on the transfer function technique and allows a fast analysis by means of the fast Fourier transform algorithm. Its efficacy has been tested both on simulated and measured temperature profiles: in all cases, the energy flux features are well reproduced and beamlets are well resolved. Limits and restrictions of the method are also discussed, providing strategies to handle issues related to signal noise and digital processing.
Analysis of diagnostic calorimeter data by the transfer function technique.
Delogu, R S; Poggi, C; Pimazzoni, A; Rossi, G; Serianni, G
2016-02-01
This paper describes the analysis procedure applied to the thermal measurements on the rear side of a carbon fibre composite calorimeter with the purpose of reconstructing the energy flux due to an ion beam colliding on the front side. The method is based on the transfer function technique and allows a fast analysis by means of the fast Fourier transform algorithm. Its efficacy has been tested both on simulated and measured temperature profiles: in all cases, the energy flux features are well reproduced and beamlets are well resolved. Limits and restrictions of the method are also discussed, providing strategies to handle issues related to signal noise and digital processing. PMID:26932104
LANDSAT-4 thematic mapper Modulation Transfer Function (MTF) evaluation
NASA Technical Reports Server (NTRS)
Schowengerdt, R. (Principal Investigator)
1983-01-01
A power spectrum (PS) analysis technique was used to compare thematic mapper (TM) A and P-tape data for a Washington, DC scene in two orthogonal directions, along scan and along track. The resulting effective modulation transfer functions (MTF) between the A and P data are repeatable from area to area and consistent with theoretical expectations. The average x-direction (along scan) MTF calculated with the PS technique is compared to the MTF of the cubic convolution resampling function used to create P data from A data. The two curves are nearly identical, indicating that the major factor affecting the image quality of P data relative to A data is the cubic convolution resampling.
Modulation transfer function measurement technique for small-pixel detectors.
Marchywka, M; Socker, D G
1992-12-01
A modulation transfer function (MTF) measurement technique suitable for large-format, small-pixel detector characterization has been investigated. A volume interference grating is used as a test image instead of the bar or sine wave target images normally used. This technique permits a high-contrast, large-area, sinusoidal intensity distribution to illuminate the device being tested, avoiding the need to deconvolve raw data with imaging system characteristics. A high-confidence MTF result at spatial frequencies near 200 cycles/mm is obtained. We present results at several visible light wavelengths with a 6.8-microm-pixel CCD. Pixel response functions are derived from the MTF results. PMID:20802584
Off-Axis Nulling Transfer Function Measurement: A First Assessment
NASA Technical Reports Server (NTRS)
Vedova, G. Dalla; Menut, J.-L.; Millour, F.; Petrov, R.; Cassaing, F.; Danchi, W. C.; Jacquinod, S.; Lhome, E.; Lopez, B.; Lozi, J.; Marcotto, A.; Parisot, J.; Reess, J.-M.
2013-01-01
We want to study a polychromatic inverse problem method with nulling interferometers to obtain information on the structures of the exozodiacal light. For this reason, during the first semester of 2013, thanks to the support of the consortium PERSEE, we launched a campaign of laboratory measurements with the nulling interferometric test bench PERSEE, operating with 9 spectral channels between J and K bands. Our objective is to characterise the transfer function, i.e. the map of the null as a function of wavelength for an off-axis source, the null being optimised on the central source or on the source photocenter. We were able to reach on-axis null depths better than 10(exp -4). This work is part of a broader project aiming at creating a simulator of a nulling interferometer in which typical noises of a real instrument are introduced. We present here our first results.
Transferred interbacterial antagonism genes augment eukaryotic innate immune function
Chou, Seemay; Daugherty, Matthew D.; Peterson, S. Brook; Biboy, Jacob; Yang, Youyun; Jutras, Brandon L.; Fritz-Laylin, Lillian K.; Ferrin, Michael A.; Harding, Brittany N.; Jacobs-Wagner, Christine; Yang, X. Frank; Vollmer, Waldemar; Malik, Harmit S.
2015-01-01
Horizontal gene transfer (HGT) allows organisms to rapidly acquire adaptive traits1. Though documented instances of HGT from bacteria to eukaryotes remain rare, bacteria represent a rich source of new functions potentially available for co-option2. One benefit that genes of bacterial origin could provide to eukaryotes is the capacity to produce anti-bacterials, which have evolved in prokaryotes as the result of eons of interbacterial competition. The type VI secretion amidase effector (Tae) proteins are potent bacteriocidal enzymes that degrade the cell wall when delivered into competing bacterial cells by the type VI secretion system (T6SS)3. Here we show that tae genes have been transferred to eukaryotes on at least six occasions, and that the resulting domesticated amidase effector (dae) genes have been preserved for hundreds of millions of years via purifying selection. We show that the dae genes acquired eukaryotic secretion signals, are expressed within recipient organisms, and encode active antibacterial toxins that possess substrate specificity matching extant Tae proteins of the same lineage. Finally, we show that a dae gene in the deer tick Ixodes scapularis limits proliferation of Borrelia burgdorferi, the etiologic agent of Lyme disease. Our work demonstrates that a family of horizontally acquired toxins honed to mediate interbacterial antagonism confers previously undescribed antibacterial capacity to eukaryotes. We speculate that the selective pressure imposed by competition between bacteria has produced a reservoir of genes encoding diverse antimicrobial functions that are tailored for facile co-option by eukaryotic innate immune systems. PMID:25470067
Komatsu, Hiroaki; Westerman, Jan; Snoek, Gerry T; Taraschi, Theodore F; Janes, Nathan
2003-12-30
Phosphatidylinositol transfer protein alpha (PITP-alpha) is a bifunctional phospholipid transfer protein that is highly selective for phosphatidylinositol (PtdIns) and phosphatidylcholine (PtdCho). Polar lipid metabolites, including L-alpha-glycerylphosphorylcholine (GroPCho), increasingly have been linked to changes in cellular function and to disease. In this study, polar lipid metabolites of PtdIns and PtdCho were tested for their ability to influence PITP-alpha activity. GroPCho inhibited the ability of PITP-alpha to transfer PtdIns or PtdCho between liposomes. The IC(50) of both processes was dependent on membrane composition. D-myo-inositol 1-phosphate and glycerylphosphorylinositol modestly enhanced PITP-alpha-mediated phospholipid transfer. Choline, phosphorylcholine (PCho), CDP-choline, glyceryl-3-phosphate, myo-inositol and D-myo-inositol 1,4,5-trisphosphate had little effect. Membrane surface charge was a strong determinant of the GroPCho inhibition with the inhibition being greatest for highly anionic membranes. GroPCho was shown to enhance the binding of PITP-alpha to anionic vesicles. In membranes of low surface charge, phosphatidylethanolamine (PtdEtn) was a determinant enabling the GroPCho inhibition. Anionic charge and PtdEtn content appeared to increase the strength of PITP-alpha-membrane interactions. The GroPCho-enhanced PITP-alpha-membrane binding was sufficient to cause inhibition, but not sufficient to account for the extent of inhibition observed. Processes associated with strengthened PITP-alpha-membrane binding in the presence of GroPCho appeared to impair the phospholipid insertion/extraction process. PMID:14729069
Function Transfer in Human Operant Experiments: The Role of Stimulus Pairings
ERIC Educational Resources Information Center
Tonneau, Francois; Gonzalez, Carmen
2004-01-01
Although function transfer often has been studied in complex operant procedures (such as matching to sample), whether operant reinforcement actually produces function transfer in such settings has not been established. The present experiments, with high school students as subjects, suggest that stimulus pairings can promote function transfer in…
On-orbit modulation transfer function characterization of terra MODIS using the moon
NASA Astrophysics Data System (ADS)
Wang, Zhipeng; Choi, Taeyoung; Xiong, Xiaoxiong
2011-10-01
The on-orbit Modulation Transfer Function (MTF) of MODIS instrument can be accurately measured by its on-board SpectroRadiometirc Calibration Assembly (SRCA). For other Earth observing instruments without calibrators similar to SRCA, the sharp edge of moon provides a reasonable high-contrast target for their on-orbit MTF characterization. In this paper, we propose a procedure to measure MODIS on-orbit MTF from the moon image. For Terra MODIS, lunar calibration was performed nearly every month since its launch in 2000. For each lunar calibration, the images of the moon from multiple scans are taken and traced across the right edge to form an edge spread function (ESF). The ESF is used to calculate a line spread function (LSF) through differentiation. The MTF in along-scan direction is then derived through the Fourier Transform of the LSF. The same procedure can also be applied to MTF calculation in along-track direction. The results are compared with SRCA measured MTF, and the long-term trending of both MTF agrees. Lunar MTF characterization appears noisier mainly because of the non-uniformity of the moon surface and moderate spatial resolution of the moon image, which makes it difficult to accurately locate the circular lunar edge in sub-pixel level. Improvement of the current method is discussed in the end.
Modulation transfer function of infrared focal plane arrays
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Rafol, S. B.; Ting, D. Z.; Soibel, A.; Hill, C. J.; Khoshakhlagh, A.; Liu, J. K.; Mumolo, J. M.; Keo, S. A.; Höglund, L.; Luong, E. M.
2015-09-01
Modulation transfer function (MTF) is the ability of an imaging system to faithfully image a given object. The MTF of an imaging system quantifies the ability of the system to resolve or transfer spatial frequencies. In this presentation we will discuss the detail MTF measurements of 1024x1024 pixels mid-wavelength and long-wavelength quantum well infrared photodetector, and 320x256 pixels long-wavelength InAs/GaSb superlattice infrared focal plane arrays (FPAs). Long wavelength Complementary Barrier Infrared Detector (CBIRD) based on InAs/GaSb superlattice material is hybridized to recently designed and fabricated 320x256 pixel format ROIC. The n-type CBIRD was characterized in terms of performance and thermal stability. The experimentally measured NEΔT of the 8.8μm cutoff n-CBIRD FPA was 18.6 mK with 300 K background and f/2 cold stop at 78K FPA operating temperature. The horizontal and vertical MTFs of this pixel fully delineated CBIRD FPA at Nyquist frequency are 49% and 52%, respectively.
Improved gene transfer with histidine-functionalized mesoporous silica nanoparticles.
Brevet, David; Hocine, Ouahiba; Delalande, Anthony; Raehm, Laurence; Charnay, Clarence; Midoux, Patrick; Durand, Jean-Olivier; Pichon, Chantal
2014-08-25
Mesoporous silica nanoparticles (MSN) were functionalized with aminopropyltriethoxysilane (MSN-NH2) then L-histidine (MSN-His) for pDNA delivery in cells and in vivo. The complexation of pDNA with MSN-NH2 and MSN-His was first studied with gel shift assay. pDNA complexed with MSN-His was better protected from DNase degradation than with MSN-NH2. An improvement of the transfection efficiency in cells was observed with MSN-His/pDNA compared to MSN-NH2/pDNA, which could be explained by a better internalization of MSN-His. The improvement of the transfection efficiency with MSN-His was also observed for gene transfer in Achilles tendons in vivo. PMID:24853464
LANDSAT-4 Thematic Mapper Modulation Transfer Function (MTF) evaluation
NASA Technical Reports Server (NTRS)
Schowengerdt, R. (Principal Investigator)
1985-01-01
The Modulation Transfer Function (MTF) for thematic mapping (TM) bands 3, 4, 5 and 7 is reliably estimated with the San Mateo Bridge target in the 12/31/82 scene. These results are to be compared with those from the 8/12/83 scene. Bands 1, 2 and 6 are to be analyzed with a different target possessing greater contrast. This may be possible with the underflight data comparison currently underway. The registration of this data to the TM image of 8/12/83 for a region arround the Stockton sewage pond east of San Francisco has begun. This particular approach has the advantage that the full two-dimensional MFT will be measured instead of the MFT in only one azimuth as reported.
Modulation-transfer-function analysis for sampled image systems
NASA Technical Reports Server (NTRS)
Park, S. K.; Kaczynski, M.-A.; Schowengerdt, R.
1984-01-01
Sampling generally causes the response of a digital imaging system to be locally shift-variant and not directly amenable to Modulation Transfer Function (MTF) analysis. However, this paper demonstrates that a meaningful system response can be calculated by averaging over an ensemble of point-source system inputs to yield an MTF which accounts for the combined effects of image formation, sampling, and image reconstruction. As an illustration, the MTF of the Landsat MSS system is analyzed to reveal an average effective instantaneous field of view which is significantly larger than the commonly accepted value, particularly in the along-track direction where undersampling contributes markedly to an MTF reduction and resultant increase in image blur.
Modulation transfer function of antenna-coupled infrared detector arrays.
Boreman, G D; Dogariu, A; Christodoulou, C; Kotter, D
1996-11-01
Individual antenna-coupled IR bolometers have recently been demonstrated at wavelengths near 10 μm. If focal-plane arrays (FPA's) of antenna-coupled detectors can be fabricated, enhancement of IR-imager performance is possible. A first step in the design process is to analyze the image-quality potential of antenna-coupled, FPA-based imagers in terms of the modulation transfer function (MTF). The key step in our analysis is development of a cross-talk MTF that accounts for the electromagnetic coupling between adjacent antennas in the FPA. We find that electromagnetic cross talk will not be a significant image-quality factor in antenna-coupled IR FPA's. PMID:21127627
Modulation transfer function of antenna-coupled infrared detector arrays
NASA Astrophysics Data System (ADS)
Boreman, Glenn D.; Dogariu, Aristide; Christodoulou, Christos; Kotter, Dale
1996-11-01
Individual antenna-coupled IR bolometers have recently been demonstrated at wavelengths near 10 mu m. If focal-plane arrays (FPA's) of antenna-coupled detectors can be fabricated, enhancement of IR-imager performance is possible. A first step in the design process is to analyze the image-quality potential of antenna-coupled, FPA-based imagers in terms of the modulation transfer function (MTF). The key step in our analysis is development of a cross-talk MTF that accounts for the electromagnetic coupling between adjacent antennas in the FPA. We find that electromagnetic cross talk will not be a significant image-quality factor in antenna-coupled IR FPA's.
Head-related transfer function database and its analyses
NASA Astrophysics Data System (ADS)
Xie, Bosun; Zhong, Xiaoli; Rao, Dan; Liang, Zhiqiang
2007-06-01
Based on the measurements from 52 Chinese subjects (26 males and 26 females), a high-spatial-resolution head-related transfer function (HRTF) database with corresponding anthropometric parameters is established. By using the database, cues relating to sound source localization, including interaural time difference (ITD), interaural level difference (ILD), and spectral features introduced by pinna, are analyzed. Moreover, the statistical relationship between ITD and anthropometric parameters is estimated. It is proved that the mean values of maximum ITD for male and female are significantly different, so are those for Chinese and western subjects. The difference in ITD is due to the difference in individual anthropometric parameters. It is further proved that the spectral features introduced by pinna strongly depend on individual; while at high frequencies (f ⩾ 5.5 kHz), HRTFs are left-right asymmetric. This work is instructive and helpful for the research on binaural hearing and applications on virtual auditory in future.
Bai, Fang; Liao, Sha; Gu, Junfeng; Jiang, Hualiang; Wang, Xicheng; Li, Honglin
2015-04-27
Metalloproteins, particularly zinc metalloproteins, are promising therapeutic targets, and recent efforts have focused on the identification of potent and selective inhibitors of these proteins. However, the ability of current drug discovery and design technologies, such as molecular docking and molecular dynamics simulations, to probe metal-ligand interactions remains limited because of their complicated coordination geometries and rough treatment in current force fields. Herein we introduce a robust, multiobjective optimization algorithm-driven metalloprotein-specific docking program named MpSDock, which runs on a scheme similar to consensus scoring consisting of a force-field-based scoring function and a knowledge-based scoring function. For this purpose, in this study, an effective knowledge-based zinc metalloprotein-specific scoring function based on the inverse Boltzmann law was designed and optimized using a dynamic sampling and iteration optimization strategy. This optimization strategy can dynamically sample and regenerate decoy poses used in each iteration step of refining the scoring function, thus dramatically improving both the effectiveness of the exploration of the binding conformational space and the sensitivity of the ranking of the native binding poses. To validate the zinc metalloprotein-specific scoring function and its special built-in docking program, denoted MpSDockZn, an extensive comparison was performed against six universal, popular docking programs: Glide XP mode, Glide SP mode, Gold, AutoDock, AutoDock4Zn, and EADock DSS. The zinc metalloprotein-specific knowledge-based scoring function exhibited prominent performance in accurately describing the geometries and interactions of the coordination bonds between the zinc ions and chelating agents of the ligands. In addition, MpSDockZn had a competitive ability to sample and identify native binding poses with a higher success rate than the other six docking programs. PMID:25746437
Himalayan sediment fluxes and the floodplain transfer function
NASA Astrophysics Data System (ADS)
Lupker, Maarten; Lavé, Jérôme; France-Lanord, Christian; Blard, Pierre Henri
2013-04-01
Erosion produces sediments and thereby redistributes mass at the Earth surface. A better understanding of these erosion processes can be gained by studying the products of erosion, i.e. the nature, magnitude and variability of sediment fluxes. On continents, rivers are the main conveyer belts that transport these sediments from source to sink. Owing to the integrative nature of river networks, a downstream river reach can be used to infer erosion processes that occur in upstream catchments. However on large spatial scales, sediment transport processes may affect the sedimentary signal so that the quantification of upstream erosion may not be straightforward. This is especially the case for continental scale basins: sediment sources are separated from sedimentary basins by large alluvial floodplains, where sediments are transported over hundreds to thousands of kilometers. The floodplain transfer function needs to be understood whenever modern river sediments or sedimentary archives are used to reconstruct present and past erosion processes. In this contribution we discuss the magnitude of sediment fluxes from the Himalayan system using sediment gauging and cosmogenic nuclide data and address to what extent sediment transport may bias these estimates. The central part of the Himalayan range is drained by two major rivers, the Ganga and Brahmaputra that convey the products of Himalayan erosion over an extensive floodplain and ultimately to the Indian Ocean. This transfer may bias erosion rates derived from gauged sediment fluxes as part of the sediment flux is trapped in the subsiding foreland basin. This storage term remains however limited and can be quantified using a geochemical budget approach [1]. Floodplain transfer may also affect cosmogenic nuclide derived sediment budgets as sediments may accumulate nuclides during transport which will increase the overall nuclide concentration and hence lead to under-estimate denudation rates. By comparing cosmogenic
Pino, Francisco; Roé, Nuria; Aguiar, Pablo; Falcon, Carles; Ros, Domènec; Pavía, Javier
2015-02-15
Purpose: Single photon emission computed tomography (SPECT) has become an important noninvasive imaging technique in small-animal research. Due to the high resolution required in small-animal SPECT systems, the spatially variant system response needs to be included in the reconstruction algorithm. Accurate modeling of the system response should result in a major improvement in the quality of reconstructed images. The aim of this study was to quantitatively assess the impact that an accurate modeling of spatially variant collimator/detector response has on image-quality parameters, using a low magnification SPECT system equipped with a pinhole collimator and a small gamma camera. Methods: Three methods were used to model the point spread function (PSF). For the first, only the geometrical pinhole aperture was included in the PSF. For the second, the septal penetration through the pinhole collimator was added. In the third method, the measured intrinsic detector response was incorporated. Tomographic spatial resolution was evaluated and contrast, recovery coefficients, contrast-to-noise ratio, and noise were quantified using a custom-built NEMA NU 4–2008 image-quality phantom. Results: A high correlation was found between the experimental data corresponding to intrinsic detector response and the fitted values obtained by means of an asymmetric Gaussian distribution. For all PSF models, resolution improved as the distance from the point source to the center of the field of view increased and when the acquisition radius diminished. An improvement of resolution was observed after a minimum of five iterations when the PSF modeling included more corrections. Contrast, recovery coefficients, and contrast-to-noise ratio were better for the same level of noise in the image when more accurate models were included. Ring-type artifacts were observed when the number of iterations exceeded 12. Conclusions: Accurate modeling of the PSF improves resolution, contrast, and recovery
Tung, Wei-Cheng; Adamowicz, Ludwik
2014-03-28
Very accurate calculations of the ground-state potential energy curve (PEC) of the LiH{sup +} ion performed with all-electron explicitly correlated Gaussian functions with shifted centers are presented. The variational method is employed. The calculations involve optimization of nonlinear exponential parameters of the Gaussians performed with the aid of the analytical first derivatives of the energy determined with respect to the parameters. The diagonal adiabatic correction is also calculated for each PEC point. The PEC is then used to calculate the vibrational energies of the system. In that calculation, the non-adiabatic effects are accounted for by using an effective vibrational mass obtained by the minimization of the difference between the vibrational energies obtained from the calculations where the Born-Oppenheimer approximation was not assumed and the results of the present calculations.
NASA Astrophysics Data System (ADS)
Zhao, P. W.; Song, L. S.; Sun, B.; Geissel, H.; Meng, J.
2012-12-01
The covariant density functional theory with the point-coupling interaction PC-PK1 is compared with new and accurate experimental masses in the element range from 50 to 91. The experimental data are from a mass measurement performed with the storage ring mass spectrometry at Gesellschaft für Schwerionenforschung (GSI) [Chen , Nucl. Phys. ANUPABL0375-947410.1016/j.nuclphysa.2012.03.002 882, 71 (2012)]. Although the microscopic theory contains only 11 parameters, it agrees well with the experimental data. The comparison is characterized by a rms deviation of 0.859 MeV. For even-even nuclei, the theory agrees within about 600 keV. Larger deviations are observed in this comparison for the odd-A and odd-odd nuclei. Improvements and possible reasons for the deviations are discussed in this contribution as well.
NASA Astrophysics Data System (ADS)
Kafri, H. Q.; Khuri, S. A.; Sayfy, A.
2016-03-01
In this paper, a novel approach is introduced for the solution of the non-linear Troesch's boundary value problem. The underlying strategy is based on Green's functions and fixed-point iterations, including Picard's and Krasnoselskii-Mann's schemes. The resulting numerical solutions are compared with both the analytical solutions and numerical solutions that exist in the literature. Convergence of the iterative schemes is proved via manipulation of the contraction principle. It is observed that the method handles the boundary layer very efficiently, reduces lengthy calculations, provides rapid convergence, and yields accurate results particularly for large eigenvalues. Indeed, to our knowledge, this is the first time that this problem is solved successfully for very large eigenvalues, actually the rate of convergence increases as the magnitude of the eigenvalues increases.
NASA Astrophysics Data System (ADS)
Bechtold, Michel; Tegge, Arne; Leiber-Sauheitl, Katharina; Tiemeyer, Bärbel; Veldhuizen, Ab; Freibauer, Annette
2014-05-01
At the point scale, many studies on greenhouse gas (GHG) emissions from peatlands are focused on developing accurate transfer functions that relate the amount of GHG emissions to site characteristics, like water table depth, vegetation and physical and chemical soil properties. Given that for a specific peatland environment such a 'point-scale' transfer function is uniquely defined, it can be spatially applied when the necessary spatial information about the function parameters is available. Assuming the point-scale transfer function was developed on an annual time scale, the spatially-variable average site conditions of one year (e.g. annual mean water table depth) can be translated into a regional estimate of the total GHG budget. When the conditions of the system change, e.g. due to rewetting measures or different climatic conditions, changes of the regional GHG budget can be estimated by applying the point-scale transfer function to the new site conditions. Here, we discuss the behavior of the GHG budget variability against changes of the spatial water table depth distribution. The latter is obtained from spatially-distributed process-based hydrological modeling using the hydrological modeling framework SIMGRO (Alterra Wageningen). The interaction of groundwater, unsaturated zone and surface water fluxes was modeled for a peatland area of 200 ha (Großes Moor, Gifhorn, Germany) using spatial information on vegetation, peat layer thickness, hydraulic properties, surface water system, system boundary conditions and a laser-scan digital elevation model (DEM) as well as measured water level time series as calibration input. Based on the water level data from various hydrological scenarios, GHG budgets were estimated. Results demonstrate that the analysis of the GHG budgets as a function of different mean regional water table depths provides insights into the behavior of the regional GHG budget for the study area. The resulting curves can be called 'regional
NASA Astrophysics Data System (ADS)
Zhang, Ningyu; Cheng, Chuanfu; Teng, Shuyun; Chen, Xiaoyi; Xu, Zhizhan
2007-09-01
A new approach based on the gated integration technique is proposed for the accurate measurement of the autocorrelation function of speckle intensities scattered from a random phase screen. The Boxcar used for this technique in the acquisition of the speckle intensity data integrates the photoelectric signal during its sampling gate open, and it repeats the sampling by a preset number, m. The average analog of the m samplings output by the Boxcar enhances the signal-to-noise ratio by √{m}, because the repeated sampling and the average make the useful speckle signals stable, while the randomly varied photoelectric noise is suppressed by 1/√{m}. In the experiment, we use an analog-to-digital converter module to synchronize all the actions such as the stepped movement of the phase screen, the repeated sampling, the readout of the averaged output of the Boxcar, etc. The experimental results show that speckle signals are better recovered from contaminated signals, and the autocorrelation function with the secondary maximum is obtained, indicating that the accuracy of the measurement of the autocorrelation function is greatly improved by the gated integration technique.
Frequency domain transfer function identification using the computer program SYSFIT
Trudnowski, D.J.
1992-12-01
Because the primary application of SYSFIT for BPA involves studying power system dynamics, this investigation was geared toward simulating the effects that might be encountered in studying electromechanical oscillations in power systems. Although the intended focus of this work is power system oscillations, the studies are sufficiently genetic that the results can be applied to many types of oscillatory systems with closely-spaced modes. In general, there are two possible ways of solving the optimization problem. One is to use a least-squares optimization function and to write the system in such a form that the problem becomes one of linear least-squares. The solution can then be obtained using a standard least-squares technique. The other method involves using a search method to obtain the optimal model. This method allows considerably more freedom in forming the optimization function and model, but it requires an initial guess of the system parameters. SYSFIT employs this second approach. Detailed investigations were conducted into three main areas: (1) fitting to exact frequency response data of a linear system; (2) fitting to the discrete Fourier transformation of noisy data; and (3) fitting to multi-path systems. The first area consisted of investigating the effects of alternative optimization cost function options; using different optimization search methods; incorrect model order, missing response data; closely-spaced poles; and closely-spaced pole-zero pairs. Within the second area, different noise colorations and levels were studied. In the third area, methods were investigated for improving fitting results by incorporating more than one system path. The following is a list of guidelines and properties developed from the study for fitting a transfer function to the frequency response of a system using optimization search methods.
Zhou, Ning; Huang, Zhenyu; Dosiek, Luke; Trudnowski, Daniel J.; Pierre, John W.
2009-07-30
Power system mode shapes are key indication of how dynamic components participate in low-frequency oscillations. Traditionally, mode shapes are calculated from a linearized dynamic model. For large-scale power systems, obtaining accu-rate dynamic models is very difficult. Therefore, measurement-based mode shape estimation methods have certain advantages, especially for the application of real-time small signal stability monitoring. In this paper, a measurement-based mode shape iden-tification method is proposed. The general relationship between transfer function (TF) and mode shape is derived. As an example, a least square (LS) method is implemented to estimate mode shape using an autoregressive exogenous (ARX) model. The per-formance of the proposed method is evaluated by Monte-Carlo studies using simulation data from a 17-machine model. The re-sults indicate the validity of the proposed method in estimating mode shapes with reasonably good accuracy
NASA Technical Reports Server (NTRS)
Wenzel, Elizabeth M.; Arruda, Marianne; Kistler, Doris J.; Wightman, Frederic L.
1993-01-01
The paper investigates the accuracy of localization by inexperienced listeners of the direction (azimuth and elevation) of wideband noisebursts presented in the free-field or over headphones, with headphone stimuli being synthesized using head-related transfer functions (HRTFs) from a representative subject of Wightman and Kistler (1989). Many subjects showed high rates of front-back and up-down confusions that increased significantly for virtual sources compared to the free-field stimuli. When confusions were resolved, localization of virtual sources was quite accurate and comparable to the free-field sources for 12 out of 16 subjects. The results of this study suggest that, while the interaural cues to horizontal location are robust, the spectral cues considered important for resolving location along a particular cone-of-confusion are distorted by a synthesis process that uses nonindividualized HRTFs.
Separation of presampling and postsampling modulation transfer functions in infrared sensor systems
NASA Astrophysics Data System (ADS)
Espinola, Richard L.; Olson, Jeffrey T.; O'Shea, Patrick D.; Hodgkin, Van A.; Jacobs, Eddie L.
2006-05-01
New methods of measuring the modulation transfer function (MTF) of electro-optical sensor systems are investigated. These methods are designed to allow the separation and extraction of presampling and postsampling components from the total system MTF. The presampling MTF includes all the effects prior to the sampling stage of the imaging process, such as optical blur and detector shape. The postsampling MTF includes all the effects after sampling, such as interpolation filters and display characteristics. Simulation and laboratory measurements are used to assess the utility of these techniques. Knowledge of these components and inclusion into sensor models, such as the U.S. Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate's NVThermIP, will allow more accurate modeling and complete characterization of sensor performance.
Research in the modulation transfer function (MTF) measurement of InGaAs focal plane arrays
NASA Astrophysics Data System (ADS)
Xu, Zhonghua; Fang, Jiaxiong
2012-10-01
The Modulation Transfer Function (MTF) of an opto-electrical device is defined as the ratio of the system output modulation to the input modulation, which describes the performance of the imaging system in the Fourier domain. Accurate measurement of the MTF is often obtained by analyzing the high-quality image of a special target reproduced by the optical system with known MTF. To evaluate the MTF of short-wave infrared InGaAs focal plane arrays (FPAs), we develop a laboratory system with high precision and automation based on the slit scan method. An 8*1 linear InGaAs FPAs is then measured by this test set-up for the first time to evaluate the MTF of each pixel at room temperature. The results show a good MTF repeatability and uniformity of the 8*1 InGaAs FPAs. The relationship between the MTF and illumination is also discussed.
NASA Astrophysics Data System (ADS)
Burks, Stephen D.; Haefner, David P.; Burks, Thomas J.
2015-05-01
Accurate Signal Intensity Transfer Functions (SITF) measurements are necessary to determine the calibration factor in the 3D noise calculation of an electro-optical imaging system. The typical means for measuring a sensor's SITF is to place the sensor in a flooded field environment at a distance that is relatively close to the aperture of the emitter. Unfortunately, this arrangement has the potential to allow for additional contributions to the SITF in the form of scattering or stray light if the optics are not designed properly in the system under test. Engineers at the US Army Night Vision and Electronic Sensors Directorate are working to determine a means of evaluating the contribution due to scatting or stray light.
Eibauer, Matthias; Hoffmann, Christian; Plitzko, Jürgen M; Baumeister, Wolfgang; Nickell, Stephan; Engelhardt, Harald
2012-12-01
Cryo-electron tomography in combination with subtomogram averaging allows to investigate the structure of protein assemblies in their natural environment in a close to live state. To make full use of the structural information contained in tomograms it is necessary to analyze the contrast transfer function (CTF) of projections and to restore the phases of higher spatial frequencies. CTF correction is however hampered by the difficulty of determining the actual defocus values from tilt series data, which is due to the low signal-to-noise ratio of electron micrographs. In this study, an extended acquisition scheme is introduced that enables an independent CTF determination. Two high-dose images are recorded along the tilt axis on both sides of each projection, which allow an accurate determination of the defocus values of these images. These values are used to calculate the CTF for each image of the tilt series. We applied this scheme to the mycobacterial outer membrane protein MspA reconstituted in lipid vesicles and tested several variants of CTF estimation in combination with subtomogram averaging and correction of the modulation transfer function (MTF). The 3D electron density map of MspA was compared with a structure previously determined by X-ray crystallography. We were able to demonstrate that structural information up to a resolution of 16.8Å can be recovered using our CTF correction approach, whereas the uncorrected 3D map had a resolution of only 26.2Å. PMID:23000705
Shah, Rupal; Breeze, John; Chand, Mohit; Stockton, Peter
2016-06-01
The index of orthognathic functional treatment need (IOFTN) is a newly-proposed system to help to prioritise patients for orthognathic treatment. The five categories are similar to those used in orthodontics, but include additional parameters such as sleep apnoea and facial asymmetry. The aim of this audit was to validate the index and find out the potential future implications, should such a system ever be adopted by commissioners. We calculated the IOFTN category of 100 consecutive patients who had orthognathic surgery between 2010-14 using clinical notes, photographs, study models, and radiographs, and determined the number in categories 4 or 5, analogous to the current indications for orthodontic treatment within the NHS. Sufficient clinical information was available to categorise 59/100 patients, and 56 of the 59 (95%) were in either category 4 or 5. All three of the remaining patients (in categories 1-3) who were operated on were treated because of the anticipated favourable impact on their quality of life. The IOFTN has been proposed for use in future commissioning of orthognathic services within the NHS, and this study has confirmed its efficacy in prioritising treatment accurately, with 95% of patients being in categories 4 or 5. We recommend that the orthognathic treatment index be adapted to include additional psychosocial assessment so that patients who fall into the lower functional categories are not automatically excluded from this potentially life-changing treatment. PMID:26935212
NASA Astrophysics Data System (ADS)
Jiménez-Teja, Y.; Benítez, N.; Molino, A.; Fernandes, C. A. C.
2015-10-01
Photometric redshifts, which have become the cornerstone of several of the largest astronomical surveys like PanStarrs, DES, J-PAS and LSST, require precise measurements of galaxy photometry in different bands using a consistent physical aperture. This is not trivial, due to the variation in the shape and width of the point spread function (PSF) introduced by wavelength differences, instrument positions and atmospheric conditions. Current methods to correct for this effect rely on a detailed knowledge of PSF characteristics as a function of the survey coordinates, which can be difficult due to the relative paucity of stars tracking the PSF behaviour. Here we show that it is possible to measure accurate, consistent multicolour photometry without knowing the shape of the PSF. The Chebyshev-Fourier functions (CHEFs) can fit the observed profile of each object and produce high signal-to-noise integrated flux measurements unaffected by the PSF. These total fluxes, which encompass all the galaxy populations, are much more useful for galaxy evolution studies than aperture photometry. We compare the total magnitudes and colours obtained using our software to traditional photometry with SEXTRACTOR, using real data from the COSMOS survey and the Hubble Ultra-Deep Field (HUDF). We also apply the CHEF technique to the recently published eXtreme Deep Field (XDF) and compare the results to those from COLORPRO on the HUDF. We produce a photometric catalogue with 35 732 sources (10 823 with signal-to-noise ratio ≥5), reaching a photometric redshift precision of 2 per cent due to the extraordinary depth and wavelength coverage of the eXtreme Deep Field images.
Zapata, Julián; Lopez, Ricardo; Herrero, Paula; Ferreira, Vicente
2012-11-30
An automated headspace in-tube extraction (ITEX) method combined with multiple headspace extraction (MHE) has been developed to provide simultaneously information about the accurate wine content in 20 relevant aroma compounds and about their relative transfer rates to the headspace and hence about the relative strength of their interactions with the matrix. In the method, 5 μL (for alcohols, acetates and carbonyl alcohols) or 200 μL (for ethyl esters) of wine sample were introduced in a 2 mL vial, heated at 35°C and extracted with 32 (for alcohols, acetates and carbonyl alcohols) or 16 (for ethyl esters) 0.5 mL pumping strokes in four consecutive extraction and analysis cycles. The application of the classical theory of Multiple Extractions makes it possible to obtain a highly reliable estimate of the total amount of volatile compound present in the sample and a second parameter, β, which is simply the proportion of volatile not transferred to the trap in one extraction cycle, but that seems to be a reliable indicator of the actual volatility of the compound in that particular wine. A study with 20 wines of different types and 1 synthetic sample has revealed the existence of significant differences in the relative volatility of 15 out of 20 odorants. Differences are particularly intense for acetaldehyde and other carbonyls, but are also notable for alcohols and long chain fatty acid ethyl esters. It is expected that these differences, linked likely to sulphur dioxide and some unknown specific compositional aspects of the wine matrix, can be responsible for relevant sensory changes, and may even be the cause explaining why the same aroma composition can produce different aroma perceptions in two different wines. PMID:23102525
Measurement of the modulation transfer function of paper.
Rogers, G L
1998-11-01
In recent years there has been a renewed interest in modeling the halftone microstructure to better control the colors produced in a halftone image. Diffusion of light within the paper has a significant effect on the halftone color; this effect is known as optical dot gain or the Yule-Neilsen effect. Because of diffusion, a photon may exit the paper from a different region of the halftone microstructure than that into which it entered the paper. To account rigorously for this effect requires knowledge of the paper's point-spread function or, equivalently, the paper's modulation transfer function (MTF). A new technique for measuring the MTF of paper-the series-expansion bar-target technique-is introduced. The method uses a bar target, but the analysis more closely resembles that of the edge-gradient technique. In the series-expansion method, bar-target image data are expanded into a Fourier series, and the paper's MTF is given by the series-expansion coefficients. It differs from the typical bar-target analysis in that the typical method plots the amplitude of the fundamental frequency component for several targets of varying frequency, whereas the series-expansion method plots the amplitude of the fundamental and its harmonics for a single target. Two possible techniques for measuring the MTF with the bar-target series-expansion method are considered. In the first, the image of the bar target is projected onto the paper, and in the second, the bar target is placed directly on the paper, in close contact. PMID:18301552
Abstracting Attribute Space for Transfer Function Exploration and Design.
Maciejewski, Ross; Jang, Yun; Woo, Insoo; Jänicke, Heike; Gaither, Kelly P; Ebert, David S
2013-01-01
Currently, user centered transfer function design begins with the user interacting with a one or two-dimensional histogram of the volumetric attribute space. The attribute space is visualized as a function of the number of voxels, allowing the user to explore the data in terms of the attribute size/magnitude. However, such visualizations provide the user with no information on the relationship between various attribute spaces (e.g., density, temperature, pressure, x, y, z) within the multivariate data. In this work, we propose a modification to the attribute space visualization in which the user is no longer presented with the magnitude of the attribute; instead, the user is presented with an information metric detailing the relationship between attributes of the multivariate volumetric data. In this way, the user can guide their exploration based on the relationship between the attribute magnitude and user selected attribute information as opposed to being constrained by only visualizing the magnitude of the attribute. We refer to this modification to the traditional histogram widget as an abstract attribute space representation. Our system utilizes common one and two-dimensional histogram widgets where the bins of the abstract attribute space now correspond to an attribute relationship in terms of the mean, standard deviation, entropy, or skewness. In this manner, we exploit the relationships and correlations present in the underlying data with respect to the dimension(s) under examination. These relationships are often times key to insight and allow us to guide attribute discovery as opposed to automatic extraction schemes which try to calculate and extract distinct attributes a priori. In this way, our system aids in the knowledge discovery of the interaction of properties within volumetric data. PMID:22508900
Ultrasonic backscatter from cancellous bone: the apparent backscatter transfer function.
Hoffmeister, Brent K; Mcpherson, Joseph A; Smathers, Morgan R; Spinolo, P Luke; Sellers, Mark E
2015-12-01
Ultrasonic backscatter techniques are being developed to detect changes in cancellous bone caused by osteoporosis. Many techniques are based on measurements of the apparent backscatter transfer function (ABTF), which represents the backscattered power from bone corrected for the frequency response of the measurement system. The ABTF is determined from a portion of the backscatter signal selected by an analysis gate of width τw delayed by an amount τd from the start of the signal. The goal of this study was to characterize the ABTF for a wide range of gate delays (1 μs ≤ τd ≤ 6 μs) and gate widths (1 μs ≤ τw ≤ 6 μs). Measurements were performed on 29 specimens of human cancellous bone in the frequency range 1.5 to 6.0 MHz using a broadband 5-MHz transducer. The ABTF was found to be an approximately linear function of frequency for most choices of τd and τw. Changes in τd and τw caused the frequency-averaged ABTF [quantified by apparent integrated backscatter (AIB)] and the frequency dependence of the ABTF [quantified by frequency slope of apparent backscatter (FSAB)] to change by as much as 24.6 dB and 6.7 dB/MHz, respectively. τd strongly influenced the measured values of AIB and FSAB and the correlation of AIB with bone density (-0.95 ≤ R ≤ +0.68). The correlation of FSAB with bone density was influenced less strongly by τd (-0.97 ≤ R ≤ -0.87). τw had a weaker influence than τd on the measured values of AIB and FSAB and the correlation of these parameters with bone density. PMID:26683412
NASA Astrophysics Data System (ADS)
Kelbert, A.; Blum, C.
2015-12-01
Magnetotelluric Transfer Functions (MT TFs) represent most of the information about Earth electrical conductivity found in the raw electromagnetic data, providing inputs for further inversion and interpretation. To be useful for scientific interpretation, they must also contain carefully recorded metadata. Making these data available in a discoverable and citable fashion would provide the most benefit to the scientific community, but such a development requires that the metadata is not only present in the file but is also searchable. The most commonly used MT TF format to date, the historical Society of Exploration Geophysicists Electromagnetic Data Interchange Standard 1987 (EDI), no longer supports some of the needs of modern magnetotellurics, most notably accurate error bars recording. Moreover, the inherent heterogeneity of EDI's and other historic MT TF formats has mostly kept the community away from healthy data sharing practices. Recently, the MT team at Oregon State University in collaboration with IRIS Data Management Center developed a new, XML-based format for MT transfer functions, and an online system for long-term storage, discovery and sharing of MT TF data worldwide (IRIS SPUD; www.iris.edu/spud/emtf). The system provides a query page where all of the MT transfer functions collected within the USArray MT experiment and other field campaigns can be searched for and downloaded; an automatic on-the-fly conversion to the historic EDI format is also included. To facilitate conversion to the new, more comprehensive and sustainable, XML format for MT TFs, and to streamline inclusion of historic data into the online database, we developed a set of open source format conversion tools, which can be used for rotation of MT TFs as well as a general XML <-> EDI converter (https://seiscode.iris.washington.edu/projects/emtf-fcu). Here, we report on the newly established collaboration between the USGS Geomagnetism Program and the Oregon State University to gather
Source effects in mid-latitude geomagnetic transfer functions
NASA Astrophysics Data System (ADS)
Araya Vargas, Jaime; Ritter, Oliver
2016-01-01
Analysis of more than 10 yr of vertical magnetic transfer function (VTF) estimates obtained at 12 mid-latitude sites, located in different continents and tectonic settings, reveals significant temporal variations for a period range between approximately 250 and 2000 s. The most ubiquitous pattern is a seasonal modulation of the VTF element that relates the vertical to the horizontal north-south magnetic components (Tx), which shows a high peak around the June solstice (and a low peak around the December solstice) regardless of the location of the site. To quantify the influence of this source effect on the amplitude of VTFs, we modelled the temporal variations of VTFs using a function with dependence on season and magnetic activity indexes. The model shows that differences between VTF estimates obtained at seasonal peaks can reach 0.08 of Tx absolute values and that the effect increases with latitude and period. Seasonal variations are observed also in the VTF component relating vertical to horizontal east-west magnetic components (Ty), but here the pattern with respect to the geographic distribution is less clear. In addition to seasonal trends, we observe long-term modulations correlating with the 11-yr solar cycle at some sites. The influence of these external source effects should be taken into account, before attempting a geological interpretation of the VTFs. It can be misleading, for example, to combine or compare VTFs obtained from long-period geomagnetic data acquired at different seasons or years. An effective method to estimate and remove these source effects from VTFs is by comparison with temporal variations of VTFs from synchronously recorded data at sites located at similar latitude (<5° of difference) and longitude (<10° of difference). Source effects in temporal variations of VTFs can be identified as those patterns that exhibit similar amplitudes and significant correlation with the geomagnetic activity at all compared sites. We also provide a
Identification of boiler inlet transfer functions and estimation of system parameters
NASA Technical Reports Server (NTRS)
Miles, J. H.
1972-01-01
An iterative computer method is described for identifying boiler transfer functions using frequency response data. An objective penalized performance measure and a nonlinear minimization technique are used to cause the locus of points generated by a transfer function to resemble the locus of points obtained from frequency response measurements. Different transfer functions can be tried until a satisfactory empirical transfer function of the system is found. To illustrate the method, some examples and some results from a study of a set of data consisting of measurements of the inlet impedance of a single tube forced flow boiler with inserts are given.
NASA Astrophysics Data System (ADS)
Ivashkov, D.; Batranin, A.; Mamyrbayev, T.
2016-01-01
In this paper presampled modulation transfer function of the 2D images obtained on the Phoenix Nanotom scanner was investigated with different measurement set-ups. Three parameters were chosen to investigate their influence on modulation transfer function: source- detector distance, tube current and binning mode. A simple method for modulation transfer function determination of digital imaging detectors from edge images was applied. The following results were achieved and briefly discussed: modulation transfer function improves with increase of the source-detector distance, slightly improves with increase of the current and remains constant for different binning modes. All measurements were carried out in University of Applied Sciences Upper Austria at Wels campus.
Is There a Linear Building Transfer Function for Small Excitation?
NASA Astrophysics Data System (ADS)
Clinton, J. F.; Heaton, T. H.
2003-12-01
application of linear transfer functions timely.
2010-01-01
Background There is an overwhelming burden of cardiovascular disease, type 2 diabetes and chronic kidney disease among Indigenous Australians. In this high risk population, it is vital that we are able to measure accurately kidney function. Glomerular filtration rate is the best overall marker of kidney function. However, differences in body build and body composition between Indigenous and non-Indigenous Australians suggest that creatinine-based estimates of glomerular filtration rate derived for European populations may not be appropriate for Indigenous Australians. The burden of kidney disease is borne disproportionately by Indigenous Australians in central and northern Australia, and there is significant heterogeneity in body build and composition within and amongst these groups. This heterogeneity might differentially affect the accuracy of estimation of glomerular filtration rate between different Indigenous groups. By assessing kidney function in Indigenous Australians from Northern Queensland, Northern Territory and Western Australia, we aim to determine a validated and practical measure of glomerular filtration rate suitable for use in all Indigenous Australians. Methods/Design A cross-sectional study of Indigenous Australian adults (target n = 600, 50% male) across 4 sites: Top End, Northern Territory; Central Australia; Far North Queensland and Western Australia. The reference measure of glomerular filtration rate was the plasma disappearance rate of iohexol over 4 hours. We will compare the accuracy of the following glomerular filtration rate measures with the reference measure: Modification of Diet in Renal Disease 4-variable formula, Chronic Kidney Disease Epidemiology Collaboration equation, Cockcroft-Gault formula and cystatin C- derived estimates. Detailed assessment of body build and composition was performed using anthropometric measurements, skinfold thicknesses, bioelectrical impedance and a sub-study used dual-energy X-ray absorptiometry. A
Assessing the transferability of ecosystem service production estimates and functions
Estimates of ecosystem service (ES) production, and their responses to stressors or policy actions, may be obtained by direct measurement, other empirical studies, or modeling. Direct measurement is costly and often impractical, and thus many studies transfer ES production estim...
Transfer Function Calibration Using AN a2 Star
NASA Astrophysics Data System (ADS)
Lupie, Olivia
1996-07-01
This proposal acquires FGS TRANS mode scans on asingle star (HD89309) for use in the reference star transfer scanlibrary. These reference scans are crucial calibrations used in theanalysis of the transfer scans of multiple systems.The binary has been studied by Otto Franz and is a puresingle star. This star has been selected to replace areference star which has subsequently shown indications ofduplicity.
Function transfer in human operant experiments: the role of stimulus pairings.
Tonneau, François; González, Carmen
2004-01-01
Although function transfer often has been studied in complex operant procedures (such as matching to sample), whether operant reinforcement actually produces function transfer in such settings has not been established. The present experiments, with high school students as subjects, suggest that stimulus pairings can promote function transfer in conditions that closely approximate those of matching to sample. In Experiment 1, the subjects showed transfer of operant responding from three geometric figures (C1, C2, C3) to three colored shapes (B1, B2, B3) when the latter were paired with the former. Experiment 2 involved two groups of subjects. In the matching group, subjects matched the colored shapes with the geometric figures; in the yoked group, the shapes were merely paired with the geometric figures, and the schedule of stimulus pairing was yoked to the performance of the subjects in the matching group. Both groups of subjects showed function transfer. Experiment 3 documented function transfer from C stimuli to B stimuli through indirect stimulus pairings (A-B, A-C). In Experiment 4, function transfer was obtained even though the subjects vocalized continuously during the pairing trials, presumably preventing covert verbalization that might mediate transfer effects. Our results are consistent with a Pavlovian account and raise difficulties for current operant theories of function transfer. PMID:15357508
Ding, Dewu; Li, Ling; Shu, Chuanjun; Sun, Xiao
2016-01-01
Shewanella oneidensis MR-1 is capable of extracellular electron transfer (EET) and hence has attracted considerable attention. The EET pathways mainly consist of c-type cytochromes, along with some other proteins involved in electron transfer processes. By whole genome study and protein interactions inquisition, we constructed a large-scale electron transfer network containing 2276 interactions among 454 electron transfer related proteins in S. oneidensis MR-1. Using the k-shell decomposition method, we identified and analyzed distinct parts of the electron transfer network. We found that there was a negative correlation between the k s (k-shell values) and the average DR_100 (disordered regions per 100 amino acids) in every shell, which suggested that disordered regions of proteins played an important role during the formation and extension of the electron transfer network. Furthermore, proteins in the top three shells of the network are mainly located in the cytoplasm and inner membrane; these proteins can be responsible for transfer of electrons into the quinone pool in a wide variety of environmental conditions. In most of the other shells, proteins are broadly located throughout the five cellular compartments (cytoplasm, inner membrane, periplasm, outer membrane, and extracellular), which ensures the important EET ability of S. oneidensis MR-1. Specifically, the fourth shell was responsible for EET and the c-type cytochromes in the remaining shells of the electron transfer network were involved in aiding EET. Taken together, these results show that there are distinct functional parts in the electron transfer network of S. oneidensis MR-1, and the EET processes could achieve high efficiency through cooperation through such an electron transfer network. PMID:27148219
Ding, Dewu; Li, Ling; Shu, Chuanjun; Sun, Xiao
2016-01-01
Shewanella oneidensis MR-1 is capable of extracellular electron transfer (EET) and hence has attracted considerable attention. The EET pathways mainly consist of c-type cytochromes, along with some other proteins involved in electron transfer processes. By whole genome study and protein interactions inquisition, we constructed a large-scale electron transfer network containing 2276 interactions among 454 electron transfer related proteins in S. oneidensis MR-1. Using the k-shell decomposition method, we identified and analyzed distinct parts of the electron transfer network. We found that there was a negative correlation between the ks (k-shell values) and the average DR_100 (disordered regions per 100 amino acids) in every shell, which suggested that disordered regions of proteins played an important role during the formation and extension of the electron transfer network. Furthermore, proteins in the top three shells of the network are mainly located in the cytoplasm and inner membrane; these proteins can be responsible for transfer of electrons into the quinone pool in a wide variety of environmental conditions. In most of the other shells, proteins are broadly located throughout the five cellular compartments (cytoplasm, inner membrane, periplasm, outer membrane, and extracellular), which ensures the important EET ability of S. oneidensis MR-1. Specifically, the fourth shell was responsible for EET and the c-type cytochromes in the remaining shells of the electron transfer network were involved in aiding EET. Taken together, these results show that there are distinct functional parts in the electron transfer network of S. oneidensis MR-1, and the EET processes could achieve high efficiency through cooperation through such an electron transfer network. PMID:27148219
Spencer, J.E.
1982-05-01
The exact, ion-optical transfer functions for the dipoles, quadrupoles and sextupoles of the PEP standard PODC cell are calculated for any single particle with initial coordinates (r, p, s). Modifications resulting from radiative energy loss are also calculated and discussed. These functions allow one to characterize individual magnets or classes of magnets by their aberrations and thereby simplify their study and correction. In contrast to high-energy spectrometers where aberrations are often analyzed away, those in storage rings drive series of high order resonances, even for perfect magnets (2), that can produce stop bands and other effects which can seriously limit performance. Thus, one would like to eliminate them altogether or failing this to develop local and global correction schemes. Even then, one should expect higher order effects to influence injection, extraction or single-pass systems either because of orbit distortions or overly large phase spece distortions such as may occur in low-beta insertions or any final-focus optics. The term exact means that the results here are based on solving the relativistic Lorentz force equation with accurate representations of measured magnetostatic fields. Such fields satisfy Maxwell's equations and are the actual fields seen by a particle as it propagates around a real storage ring. This is discussed in detail and illustrated with examples that show that this is possible, practical and may even be useful.
Lee, Changwoo; Baek, Jongduk
2016-03-01
We propose a sphere phantom approach to measure spatially varying directional modulation transfer functions (MTFs) for tomosynthesis imaging systems. Since the reconstructed tomosynthesis images contain significant artifacts, traditional background detrending techniques may not be effective to estimate the background trends accurately, which is essential to acquire sphere only data. A background detrending technique optimized for local volumes with different cone angles is presented. To measure directional MTFs, we calculate plane integrals of ideal sphere phantom and sphere only data. To minimize the effects of the high level of noise in tomosynthesis images, Richardson-Lucy deconvolution with Tikhonov-Miller is used to estimate directional plane spread function (PlSF). Then, directional MTFs are calculated by taking the modulus of the Fourier transform of the directional PlSFs. The measured directional MTFs are compared with the ideal directional MTFs calculated from a simulated point object. Our results show that the proposed method reliably measures directional MTFs along any desired directions, especially near low frequency regions. PMID:26571519
Hammond, J.; Govind, N.; Kowalski, K.; Autschbach, J.; Xantheas, S.; PNNL; Univ. of Buffalo
2009-12-07
The static dipole polarizabilities of water clusters (2 {le} N {le} 12) are determined at the coupled-cluster level of theory (CCSD). For the dipole polarizability of the water monomer it was determined that the role of the basis set is more important than that of electron correlation and that the basis set augmentation converges with two sets of diffuse functions. The CCSD results are used to benchmark a variety of density functionals while the performance of several families of basis sets (Dunning, Pople, and Sadlej) in producing accurate values for the polarizabilities was also examined. The Sadlej family of basis sets was found to produce accurate results when compared to the ones obtained with the much larger Dunning basis sets. It was furthermore determined that the PBE0 density functional with the aug-cc-pVDZ basis set produces overall remarkably accurate polarizabilities at a moderate computational cost.
Holographic elements for modulation transfer function testing of detector arrays
NASA Astrophysics Data System (ADS)
Ducharme, Alfred D.; Boreman, Glenn D.
1995-08-01
A holographic technique is presented that increases the flux-transfer efficiency of laser speckle generation by a factor of 100 over the integrating sphere method. This makes a wider range of low-power lasers usable for the speckle MTF test, method, and increases the number of wavelengths at which the test can be applied.
The Transfer Velocity Project: A Comprehensive Look at the Transfer Function
ERIC Educational Resources Information Center
Hayward, Craig
2011-01-01
The 1999-2000 Transfer Velocity Project (TVP) cohort of 147,207 community college students is used to develop both a college-level endogenous model, appropriate for applied research and guidance for campus action, and a student-level model. Survival analysis (Cox regression) is employed to evaluate the relative contribution of 53 student-level…
Imaging performance of annular apertures. III - Apodization and modulation transfer functions
NASA Technical Reports Server (NTRS)
Tschunko, H. F. A.
1979-01-01
Apodization functions with decreasing transmission and their opposite, functions with increasing transmission, are investigated for various central obstruction ratios. The resultant modulation transfer functions are presented for various transmission functions and central obstruction ratios. Conclusions applicable to the improvement of imaging performance are discussed.
Xu, Haojie; Lu, Yunfeng; Zhu, Shanan
2014-01-01
It is of significance to assess the dynamic spectral causality among physiological signals. Several practical estimators adapted from spectral Granger causality have been exploited to track dynamic causality based on the framework of time-varying multivariate autoregressive (tvMVAR) models. The non-zero covariance of the model’s residuals has been used to describe the instantaneous effect phenomenon in some causality estimators. However, for the situations with Gaussian residuals in some autoregressive models, it is challenging to distinguish the directed instantaneous causality if the sufficient prior information about the “causal ordering” is missing. Here, we propose a new algorithm to assess the time-varying causal ordering of tvMVAR model under the assumption that the signals follow the same acyclic causal ordering for all time lags and to estimate the instantaneous effect factor (IEF) value in order to track the dynamic directed instantaneous connectivity. The time-lagged adaptive directed transfer function (ADTF) is also estimated to assess the lagged causality after removing the instantaneous effect. In the present study, we firstly investigated the performance of the causal-ordering estimation algorithm and the accuracy of IEF value. Then, we presented the results of IEF and time-lagged ADTF method by comparing with the conventional ADTF method through simulations of various propagation models. Statistical analysis results suggest that the new algorithm could accurately estimate the causal ordering and give a good estimation of the IEF values in the Gaussian residual conditions. Meanwhile, the time-lagged ADTF approach is also more accurate in estimating the time-lagged dynamic interactions in a complex nervous system after extracting the instantaneous effect. In addition to the simulation studies, we applied the proposed method to estimate the dynamic spectral causality on real visual evoked potential (VEP) data in a human subject. Its usefulness in
Characterizing short-term stability for Boolean networks over any distribution of transfer functions
NASA Astrophysics Data System (ADS)
Seshadhri, C.; Smith, Andrew M.; Vorobeychik, Yevgeniy; Mayo, Jackson R.; Armstrong, Robert C.
2016-07-01
We present a characterization of short-term stability of Kauffman's N K (random) Boolean networks under arbitrary distributions of transfer functions. Given such a Boolean network where each transfer function is drawn from the same distribution, we present a formula that determines whether short-term chaos (damage spreading) will happen. Our main technical tool which enables the formal proof of this formula is the Fourier analysis of Boolean functions, which describes such functions as multilinear polynomials over the inputs. Numerical simulations on mixtures of threshold functions and nested canalyzing functions demonstrate the formula's correctness.
Seshadhri, C; Smith, Andrew M; Vorobeychik, Yevgeniy; Mayo, Jackson R; Armstrong, Robert C
2016-07-01
We present a characterization of short-term stability of Kauffman's NK (random) Boolean networks under arbitrary distributions of transfer functions. Given such a Boolean network where each transfer function is drawn from the same distribution, we present a formula that determines whether short-term chaos (damage spreading) will happen. Our main technical tool which enables the formal proof of this formula is the Fourier analysis of Boolean functions, which describes such functions as multilinear polynomials over the inputs. Numerical simulations on mixtures of threshold functions and nested canalyzing functions demonstrate the formula's correctness. PMID:27575142
Gao, Mingwu; Rose, William C; Fetics, Barry; Kass, David A; Chen, Chen-Huan; Mukkamala, Ramakrishna
2016-01-01
Generalized transfer functions (GTFs) are available to compute the more relevant central blood pressure (BP) waveform from a more easily measured radial BP waveform. However, GTFs are population averages and therefore may not adapt to variations in pulse pressure (PP) amplification (ratio of radial to central PP). A simple adaptive transfer function (ATF) was developed. First, the transfer function is defined in terms of the wave travel time and reflection coefficient parameters of an arterial model. Then, the parameters are estimated from the radial BP waveform by exploiting the observation that central BP waveforms exhibit exponential diastolic decays. The ATF was assessed using the original data that helped popularize the GTF. These data included radial BP waveforms and invasive reference central BP waveforms from cardiac catheterization patients. The data were divided into low, middle, and high PP amplification groups. The ATF estimated central BP with greater accuracy than GTFs in the low PP amplification group (e.g., central systolic BP and PP root-mean-square-errors of 3.3 and 4.2 mm Hg versus 6.2 and 7.1 mm Hg; p ≤ 0.05) while showing similar accuracy in the higher PP amplification groups. The ATF may permit more accurate, non-invasive central BP monitoring in elderly and hypertensive patients. PMID:27624389
Directional 2D functions as models for fast layout pattern transfer verification
NASA Astrophysics Data System (ADS)
Torres, J. Andres; Hofmann, Mark; Otto, Oberdan
2009-03-01
As advanced manufacturing processes become more stable, the need to adapt new designs to fully utilize the available manufacturing technology becomes a key technologic differentiator. However, many times such gains can only be realized and evaluated during full chip analysis. It has been demonstrated that the most accurate layout verification methods require application of the actual OPC recipes along with most of the mask data preparation that defines the pattern transfer characteristics of the process. Still, this method in many instances is not sufficiently fast to be used in a layout creation environment which undergoes constant updates. By doing an analysis of typical mask data processing, it is possible to determine that the most CPUintensive computations are the OPC and contour simulation steps needed to perform layout printability checks. Several researchers have tried to reduce the time it takes to compute the OPC mask by introducing matrix convolutions of the layout with empirically calibrated two-dimensional functions. However, most of these approaches do not provide a sufficient speed-up since they only replace the OPC computation and still require a full contour computation. Another alternative is to try to find effective ways of pattern matching those topologies that will exhibit transfer difficulties4, but such methods lack the ability to be predictive beyond their calibration data. In this paper we present a methodology that includes common resolution enhancement techniques, such as retargeting and sub-resolution assist feature insertion, and which replaces the OPC computation and subsequent contour calculation with an edge bias function based on an empirically-calibrated, directional, two-dimensional function. Because the edge bias function does not provide adequate control over the corner locations, a spline-based smoothing process is applied. The outcome is a piecewise-linear curve similar to those obtained by full lithographic simulations. Our
NASA Technical Reports Server (NTRS)
Zoladz, Tom; Patel, Sandeep; Lee, Erik; Karon, Dave
2011-01-01
An advanced methodology for extracting the hydraulic dynamic pump transfer matrix (Yp) for a cavitating liquid rocket engine turbopump inducer+impeller has been developed. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Laboratory pulsed subscale waterflow test of the J-2X oxygen turbo pump is introduced and our new extraction method applied to the data collected. From accurate measures of pump inlet and discharge perturbational mass flows and pressures, and one-dimensional flow models that represents complete waterflow loop physics, we are able to derive Yp and hence extract the characteristic pump parameters: compliance, pump gain, impedance, mass flow gain. Detailed modeling is necessary to accurately translate instrument plane measurements to the pump inlet and discharge and extract Yp. We present the MSFC Dynamic Lump Parameter Fluid Model Framework and describe critical dynamic component details. We report on fit minimization techniques, cost (fitness) function derivation, and resulting model fits to our experimental data are presented. Comparisons are made to alternate techniques for spatially translating measurement stations to actual pump inlet and discharge.
Experimental characterization of the transfer function for a Silver-dielectric superlens.
Moore, Ciaran P; Blaikie, Richard J
2012-03-12
We describe a technique for experimentally determining the spatial-frequency modulation transfer function for near-field super-resolution imaging systems and present such a modulation transfer function for a 20|40|20 nm poly(vinyl alcohol)~(PVA)|Silver|PVA superlens exposed to 365 nm wavelength (i-line) radiation through a 50-nm thick tungsten mask. An extensive spectral characterization is achieved from only two exposures, with transmission coefficients determined for spatial frequencies as high as 13 µm-1, corresponding to λ / 4.75. The resulting transfer function is in good agreement with analytical models that incorporate the effects of mask-superlens interactions. PMID:22418523
Transfer of Chemically Modified Graphene with Retention of Functionality for Surface Engineering.
Whitener, Keith E; Lee, Woo-Kyung; Bassim, Nabil D; Stroud, Rhonda M; Robinson, Jeremy T; Sheehan, Paul E
2016-02-10
Single-layer graphene chemically reduced by the Birch process delaminates from a Si/SiOx substrate when exposed to an ethanol/water mixture, enabling transfer of chemically functionalized graphene to arbitrary substrates such as metals, dielectrics, and polymers. Unlike in previous reports, the graphene retains hydrogen, methyl, and aryl functional groups during the transfer process. This enables one to functionalize the receiving substrate with the properties of the chemically modified graphene (CMG). For instance, magnetic force microscopy shows that the previously reported magnetic properties of partially hydrogenated graphene remain after transfer. We also transfer hydrogenated graphene from its copper growth substrate to a Si/SiOx wafer and thermally dehydrogenate it to demonstrate a polymer- and etchant-free graphene transfer for potential use in transmission electron microscopy. Finally, we show that the Birch reduction facilitates delamination of CMG by weakening van der Waals forces between graphene and its substrate. PMID:26784372
WSINV3DMT: Vertical magnetic field transfer function inversion and parallel implementation
NASA Astrophysics Data System (ADS)
Siripunvaraporn, Weerachai; Egbert, Gary
2009-04-01
We describe two extensions to the three-dimensional magnetotelluric inversion program WSINV3DMT (Siripunvaraporn, W., Egbert, G., Lenbury, Y., Uyeshima, M., 2005, Three-dimensional magnetotelluric inversion: data-space method. Phys. Earth Planet. Interiors 150, 3-14), including modifications to allow inversion of the vertical magnetic transfer functions (VTFs), and parallelization of the code. The parallel implementation, which is most appropriate for small clusters, uses MPI to distribute forward solutions for different frequencies, as well as some linear algebraic computations, over multiple processors. In addition to reducing run times, the parallelization reduces memory requirements by distributing storage of the sensitivity matrix. Both new features are tested on synthetic and real datasets, revealing nearly linear speedup for a small number of processors (up to 8). Experiments on synthetic examples show that the horizontal position and lateral conductivity contrasts of anomalies can be recovered by inverting VTFs alone. However, vertical positions and absolute amplitudes are not well constrained unless an accurate host resistivity is imposed a priori. On very simple synthetic models including VTFs in a joint inversion had little impact on the inverse solution computed with impedances alone. However, in experiments with real data, inverse solutions obtained from joint inversion of VTF and impedances, and from impedances alone, differed in important ways, suggesting that for structures with more realistic levels of complexity the VTFs will in general provide useful additional constraints.
NASA Astrophysics Data System (ADS)
Wang, Wei-Chung; Hwang, Chi Hung; Chen, Yung-Hsiang; Chuang, Tzu-Hung
2013-06-01
The digital image correlation (DIC) method has been well recognized as a simple, accurate and efficient method for mechanical behavior evaluation. However, very few researches have concentrated on the relationship between the characteristics of the camera lens and the measurement error of the DIC method. The modulation transfer function (MTF) has commonly used for evaluation of the resolution capability of camera lens. In practice, when the DIC method is used, it is possible that the captured images become too blur to analyze when the object is out of the focus of the camera lens or the object deviates from the line-of-view of the camera. In this paper, the traditional MTF calibration specimen was replaced by a pre-arranged speckle pattern on the specimen. For DIC images grabbed from several selected locations both approaching and departing from the focus of the camera lens, corresponding MTF curves were obtained from the pre-arranged speckle pattern. The displacement measurement errors of the DIC method were then estimated by those obtained MTF curves.
NASA Astrophysics Data System (ADS)
Barnard, Kenneth J.; Anisimov, Igor; Scheihing, John E.
2012-08-01
Direct measurement of the modulation transfer function (MTF) of focal plane arrays (FPAs) using random laser speckle approaches for the visible/near-infrared wavelength band has been well documented over the last 20 years. These methods have not transitioned to the midwave infrared (MWIR) primarily because other techniques have been sufficient and MWIR laser sources with sufficient output power have been unavailable. However, as the detector pitch decreases, MTF measurements become more difficult due to diffraction, while potential MTF degradation due to lateral carrier diffusion crosstalk makes accurate MTF characterization critical for sensor system design. Here, a random laser speckle FPA MTF measurement approach is adapted for use in the MWIR that utilizes a quantum cascade laser coupled with an integrating sphere to generate the appropriate in-band random speckle. Specific challenges associated with the technique are addressed including the validity of the Fresnel diffraction assumptions describing the propagation of the random speckle field from the integrating sphere to the FPA. Improved methods for estimating the power spectral density (PSD) of the measured speckle that reduce data requirements are presented. The statistics and uniformity of the laser speckle are presented along with PSD measurements and estimated MTFs of a MWIR FPA.
NASA Astrophysics Data System (ADS)
Alexandrakis, Catherine; Eaton, David W.
2007-11-01
SmKS waves provide good resolution of outer-core velocity structure, but are affected by heterogeneity in the D'' region. We have developed an Empirical Transfer Function (ETF) technique that transforms a reference pulse (here, SmKS) into a target waveform (SKKS) by: (1) time-windowing the respective pulses, (2) applying Wiener deconvolution, and (3) convolving the output with a Gaussian waveform. Common source and path effects are implicitly removed by this process. We combine ETFs from 446 broadband seismograms to produce a global stack, from which S3KS-SKKS differential time can be measured accurately. As a result of stacking, the scatter in our measurements (0.43 s) is much less than the 1.29 s scatter in previous compilations. Although our data do not uniquely constrain outermost core velocities, we show that the fit of most standard models can be improved by perturbing the outermost core velocity. Our best-fitting model is formed using IASP91 with PREM-like velocity at the top of the core.
Training and Transfer Effects of Executive Functions in Preschool Children
ERIC Educational Resources Information Center
Thorell, Lisa B.; Lindqvist, Sofia; Nutley, Sissela Bergman; Bohlin, Gunilla; Klingberg, Torkel
2009-01-01
Executive functions, including working memory and inhibition, are of central importance to much of human behavior. Interventions intended to improve executive functions might therefore serve an important purpose. Previous studies show that working memory can be improved by training, but it is unknown if this also holds for inhibition, and whether…
Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman
Sauer, M.V.; Macaso, T.M.; Ishida, E.H.; Giudice, L.; Marshall, J.R.; Buster, J.E.
1987-08-01
We report this country's first nonsurgical donor ovum transfer pregnancy in a functionally agonadal woman who had received chemotherapy and radiation for Hodgkin's lymphoma. For women with ovarian failure, nonsurgical uterine lavage and ovum transfer may provide an opportunity for motherhood that was not possible previously.
Janke, Svenja M; Auerbach, Daniel J; Wodtke, Alec M; Kandratsenka, Alexander
2015-09-28
We have constructed a potential energy surface (PES) for H-atoms interacting with fcc Au(111) based on fitting the analytic form of the energy from Effective Medium Theory (EMT) to ab initio energy values calculated with density functional theory. The fit used input from configurations of the H-Au system with Au atoms at their lattice positions as well as configurations with the Au atoms displaced from their lattice positions. It reproduces the energy, in full dimension, not only for the configurations used as input but also for a large number of additional configurations derived from ab initio molecular dynamics (AIMD) trajectories at finite temperature. Adiabatic molecular dynamics simulations on this PES reproduce the energy loss behavior of AIMD. EMT also provides expressions for the embedding electron density, which enabled us to develop a self-consistent approach to simulate nonadiabatic electron-hole pair excitation and their effect on the motion of the incident H-atoms. For H atoms with an energy of 2.7 eV colliding with Au, electron-hole pair excitation is by far the most important energy loss pathway, giving an average energy loss ≈3 times that of the adiabatic case. This increased energy loss enhances the probability of the H-atom remaining on or in the Au slab by a factor of 2. The most likely outcome for H-atoms that are not scattered also depends prodigiously on the energy transfer mechanism; for the nonadiabatic case, more than 50% of the H-atoms which do not scatter are adsorbed on the surface, while for the adiabatic case more than 50% pass entirely through the 4 layer simulation slab. PMID:26429033
Janke, Svenja M.; Auerbach, Daniel J.; Kandratsenka, Alexander; Wodtke, Alec M.
2015-09-28
We have constructed a potential energy surface (PES) for H-atoms interacting with fcc Au(111) based on fitting the analytic form of the energy from Effective Medium Theory (EMT) to ab initio energy values calculated with density functional theory. The fit used input from configurations of the H–Au system with Au atoms at their lattice positions as well as configurations with the Au atoms displaced from their lattice positions. It reproduces the energy, in full dimension, not only for the configurations used as input but also for a large number of additional configurations derived from ab initio molecular dynamics (AIMD) trajectories at finite temperature. Adiabatic molecular dynamics simulations on this PES reproduce the energy loss behavior of AIMD. EMT also provides expressions for the embedding electron density, which enabled us to develop a self-consistent approach to simulate nonadiabatic electron-hole pair excitation and their effect on the motion of the incident H-atoms. For H atoms with an energy of 2.7 eV colliding with Au, electron-hole pair excitation is by far the most important energy loss pathway, giving an average energy loss ≈3 times that of the adiabatic case. This increased energy loss enhances the probability of the H-atom remaining on or in the Au slab by a factor of 2. The most likely outcome for H-atoms that are not scattered also depends prodigiously on the energy transfer mechanism; for the nonadiabatic case, more than 50% of the H-atoms which do not scatter are adsorbed on the surface, while for the adiabatic case more than 50% pass entirely through the 4 layer simulation slab.
OrbView-3 Technical Performance Evaluation 2005: Modulation Transfer Function
NASA Technical Reports Server (NTRS)
Cole, Aaron
2007-01-01
The Technical performance evaluation of OrbView-3 using the Modulation Transfer Function (MTF) is presented. The contents include: 1) MTF Results and Methodology; 2) Radiometric Calibration Methodology; and 3) Relative Radiometric Assessment Results
Semi-automatic time-series transfer functions via temporal clustering and sequencing
Woodring, Jonathan L; Shen, H W
2009-01-01
When creating transfer functions for time-varying data, it is not clear what range of values to use for classification, as data value ranges and distributions change over time. In order to generate time-varying transfer functions, they search the data for classes that have similar behavior over time, assuming that data points that behave similarly belong to the same feature. They utilize a method they call temporal clustering and sequencing to find dynamic features in value space and create a corresponding transfer function. First, clustering finds groups of data points that have the same value space activity over time. Then, sequencing derives a progression of clusters over time, creating chains that follow value distribution changes. Finally, the cluster sequences are used to create transfer functions, as sequences describe the value range distributions over time in a data set.
Measurement and modeling of transfer functions for lightning coupling into the Sago mine.
Morris, Marvin E.; Higgins, Matthew B.
2007-04-01
This report documents measurements and analytical modeling of electromagnetic transfer functions to quantify the ability of cloud-to-ground lightning strokes (including horizontal arc-channel components) to couple electromagnetic energy into the Sago mine located near Buckhannon, WV. Two coupling mechanisms were measured: direct and indirect drive. These transfer functions are then used to predict electric fields within the mine and induced voltages on conductors that were left abandoned in the sealed area of the Sago mine.
An accurate registration technique for distorted images
NASA Technical Reports Server (NTRS)
Delapena, Michele; Shaw, Richard A.; Linde, Peter; Dravins, Dainis
1990-01-01
Accurate registration of International Ultraviolet Explorer (IUE) images is crucial because the variability of the geometrical distortions that are introduced by the SEC-Vidicon cameras ensures that raw science images are never perfectly aligned with the Intensity Transfer Functions (ITFs) (i.e., graded floodlamp exposures that are used to linearize and normalize the camera response). A technique for precisely registering IUE images which uses a cross correlation of the fixed pattern that exists in all raw IUE images is described.
Transfer Relations Between Landscape Functions - The Hydrological Point of View
NASA Astrophysics Data System (ADS)
Fohrer, N.; Lenhart, T.; Eckhardt, K.; Frede, H.-G.
EC market policies and regional subsidy programs have an enormous impact on local land use. This has far reaching consequences on various landscape functions. In the joint research project SFB299 at the Giessen University the effect of land use options on economic, ecological and hydrological landscape functions are under investigation. The continuous time step model SWAT-G (Eckhardt et al., 2000; Arnold et al., 1998) is employed to characterize the influence of land use patterns on hydrological processes. The model was calibrated and validated employing a split sample approach. For two mesoscale watersheds (Aar, 60 km2; Dietzhölze, 81 km2) located in the Lahn-Dill- Bergland, Germany, different land use scenarios were analyzed with regard to their hydrological impact. Additionally the effect of land use change was analyzed with an ecological and an agro-economic model. The impact of the stepwise changing land use was expressed as trade off relations between different landscape functions.
Functionalization of Rhenium Aryl Bonds by O-Atom Transfer
Bischof, Steven M.; Cheng, Mu-Jeng; Nielsen, Robert J.; Gunnoe, T. Brent; Goddard, William A.; Periana, Roy A.
2011-03-29
Aryltrioxorhenium (ArReO_{3}) has been demonstrated to show rapid oxy-functionalization upon reaction with O-atom donors, YO, to selectively generate the corresponding phenols in near quantitative yields. ^{18}O-Labeling experiments show that the oxygen in the products is exclusively from YO. DFT studies reveal a 10.7 kcal/mol barrier (Ar = Ph) for oxy-functionalization with H_{2}O_{2} via a Baeyer-Villiger type mechanism involving nucleophilic attack of the aryl group on an electrophilic oxygen of YO coordinated to rhenium.
The use of algorithmic behavioural transfer functions in parametric EO system performance models
NASA Astrophysics Data System (ADS)
Hickman, Duncan L.; Smith, Moira I.
2015-10-01
The use of mathematical models to predict the overall performance of an electro-optic (EO) system is well-established as a methodology and is used widely to support requirements definition, system design, and produce performance predictions. Traditionally these models have been based upon cascades of transfer functions based on established physical theory, such as the calculation of signal levels from radiometry equations, as well as the use of statistical models. However, the performance of an EO system is increasing being dominated by the on-board processing of the image data and this automated interpretation of image content is complex in nature and presents significant modelling challenges. Models and simulations of EO systems tend to either involve processing of image data as part of a performance simulation (image-flow) or else a series of mathematical functions that attempt to define the overall system characteristics (parametric). The former approach is generally more accurate but statistically and theoretically weak in terms of specific operational scenarios, and is also time consuming. The latter approach is generally faster but is unable to provide accurate predictions of a system's performance under operational conditions. An alternative and novel architecture is presented in this paper which combines the processing speed attributes of parametric models with the accuracy of image-flow representations in a statistically valid framework. An additional dimension needed to create an effective simulation is a robust software design whose architecture reflects the structure of the EO System and its interfaces. As such, the design of the simulator can be viewed as a software prototype of a new EO System or an abstraction of an existing design. This new approach has been used successfully to model a number of complex military systems and has been shown to combine improved performance estimation with speed of computation. Within the paper details of the approach
Modeling the Transfer Function for the Dark Energy Survey
Chang, C.
2015-03-04
We present a forward-modeling simulation framework designed to model the data products from the Dark Energy Survey (DES). This forward-model process can be thought of as a transfer function—a mapping from cosmological/astronomical signals to the final data products used by the scientists. Using output from the cosmological simulations (the Blind Cosmology Challenge), we generate simulated images (the Ultra Fast Image Simulator) and catalogs representative of the DES data. In this work we demonstrate the framework by simulating the 244 deg2 coadd images and catalogs in five bands for the DES Science Verification data. The simulation output is compared with themore » corresponding data to show that major characteristics of the images and catalogs can be captured. We also point out several directions of future improvements. Two practical examples—star-galaxy classification and proximity effects on object detection—are then used to illustrate how one can use the simulations to address systematics issues in data analysis. With clear understanding of the simplifications in our model, we show that one can use the simulations side-by-side with data products to interpret the measurements. This forward modeling approach is generally applicable for other upcoming and future surveys. It provides a powerful tool for systematics studies that is sufficiently realistic and highly controllable.« less
Modeling the Transfer Function for the Dark Energy Survey
NASA Astrophysics Data System (ADS)
Chang, C.; Busha, M. T.; Wechsler, R. H.; Refregier, A.; Amara, A.; Rykoff, E.; Becker, M. R.; Bruderer, C.; Gamper, L.; Leistedt, B.; Peiris, H.; Abbott, T.; Abdalla, F. B.; Balbinot, E.; Banerji, M.; Bernstein, R. A.; Bertin, E.; Brooks, D.; Carnero, A.; Desai, S.; da Costa, L. N.; Cunha, C. E.; Eifler, T.; Evrard, A. E.; Fausti Neto, A.; Gerdes, D.; Gruen, D.; James, D.; Kuehn, K.; Maia, M. A. G.; Makler, M.; Ogando, R.; Plazas, A.; Sanchez, E.; Santiago, B.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, C.; Soares-Santos, M.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Zuntz, J.
2015-03-01
We present a forward-modeling simulation framework designed to model the data products from the Dark Energy Survey (DES). This forward-model process can be thought of as a transfer function—a mapping from cosmological/astronomical signals to the final data products used by the scientists. Using output from the cosmological simulations (the Blind Cosmology Challenge), we generate simulated images (the Ultra Fast Image Simulator) and catalogs representative of the DES data. In this work we demonstrate the framework by simulating the 244 deg2 coadd images and catalogs in five bands for the DES Science Verification data. The simulation output is compared with the corresponding data to show that major characteristics of the images and catalogs can be captured. We also point out several directions of future improvements. Two practical examples—star-galaxy classification and proximity effects on object detection—are then used to illustrate how one can use the simulations to address systematics issues in data analysis. With clear understanding of the simplifications in our model, we show that one can use the simulations side-by-side with data products to interpret the measurements. This forward modeling approach is generally applicable for other upcoming and future surveys. It provides a powerful tool for systematics studies that is sufficiently realistic and highly controllable.
Modeling the Transfer Function for the Dark Energy Survey
Chang, C.
2015-03-04
We present a forward-modeling simulation framework designed to model the data products from the Dark Energy Survey (DES). This forward-model process can be thought of as a transfer function—a mapping from cosmological/astronomical signals to the final data products used by the scientists. Using output from the cosmological simulations (the Blind Cosmology Challenge), we generate simulated images (the Ultra Fast Image Simulator) and catalogs representative of the DES data. In this work we demonstrate the framework by simulating the 244 deg^{2} coadd images and catalogs in five bands for the DES Science Verification data. The simulation output is compared with the corresponding data to show that major characteristics of the images and catalogs can be captured. We also point out several directions of future improvements. Two practical examples—star-galaxy classification and proximity effects on object detection—are then used to illustrate how one can use the simulations to address systematics issues in data analysis. With clear understanding of the simplifications in our model, we show that one can use the simulations side-by-side with data products to interpret the measurements. This forward modeling approach is generally applicable for other upcoming and future surveys. It provides a powerful tool for systematics studies that is sufficiently realistic and highly controllable.
A High-Accurate and High-Efficient Monte Carlo Code by Improved Molière Functions with Ionization
NASA Astrophysics Data System (ADS)
Nakatsuka, Takao; Okei, Kazuhide
2003-07-01
Although the Molière theory of multiple Coulomb scattering is less accue rate in tracing solid angles than the Goudsmit and Saunderson theory due to the small angle approximation, it still acts very important roles in developments of high-efficient simulation codes of relativistic charged particles like cosmic-ray particles. Molière expansion is well explained by the physical model, that is the e normal distribution attributing to the high-frequent moderate scatterings and subsequent correction terms attributing to the additive large-angle scatterings. Based on these physical concepts, we have improved a high-accurate and highefficient Monte Carlo code taking account of ionization loss.
Gallandi, Lukas; Marom, Noa; Rinke, Patrick; Körzdörfer, Thomas
2016-02-01
The performance of non-empirically tuned long-range corrected hybrid functionals for the prediction of vertical ionization potentials (IPs) and electron affinities (EAs) is assessed for a set of 24 organic acceptor molecules. Basis set-extrapolated coupled cluster singles, doubles, and perturbative triples [CCSD(T)] calculations serve as a reference for this study. Compared to standard exchange-correlation functionals, tuned long-range corrected hybrid functionals produce highly reliable results for vertical IPs and EAs, yielding mean absolute errors on par with computationally more demanding GW calculations. In particular, it is demonstrated that long-range corrected hybrid functionals serve as ideal starting points for non-self-consistent GW calculations. PMID:26731340
Sutton, Christopher; Gray, Matthew T.; Brunsfeld, Max; Parrish, Robert M.; Sherrill, C. David; Sears, John S.; Brédas, Jean-Luc E-mail: thomas.koerzdoerfer@uni-potsdam.de; Körzdörfer, Thomas E-mail: thomas.koerzdoerfer@uni-potsdam.de
2014-02-07
We investigate the torsion potentials in two prototypical π-conjugated polymers, polyacetylene and polydiacetylene, as a function of chain length using different flavors of density functional theory. Our study provides a quantitative analysis of the delocalization error in standard semilocal and hybrid density functionals and demonstrates how it can influence structural and thermodynamic properties. The delocalization error is quantified by evaluating the many-electron self-interaction error (MESIE) for fractional electron numbers, which allows us to establish a direct connection between the MESIE and the error in the torsion barriers. The use of non-empirically tuned long-range corrected hybrid functionals results in a very significant reduction of the MESIE and leads to an improved description of torsion barrier heights. In addition, we demonstrate how our analysis allows the determination of the effective conjugation length in polyacetylene and polydiacetylene chains.
NASA Technical Reports Server (NTRS)
Ko, William L.; Fleischer, Van Tran
2012-01-01
In the formulations of earlier Displacement Transfer Functions for structure shape predictions, the surface strain distributions, along a strain-sensing line, were represented with piecewise linear functions. To improve the shape-prediction accuracies, Improved Displacement Transfer Functions were formulated using piecewise nonlinear strain representations. Through discretization of an embedded beam (depth-wise cross section of a structure along a strain-sensing line) into multiple small domains, piecewise nonlinear functions were used to describe the surface strain distributions along the discretized embedded beam. Such piecewise approach enabled the piecewise integrations of the embedded beam curvature equations to yield slope and deflection equations in recursive forms. The resulting Improved Displacement Transfer Functions, written in summation forms, were expressed in terms of beam geometrical parameters and surface strains along the strain-sensing line. By feeding the surface strains into the Improved Displacement Transfer Functions, structural deflections could be calculated at multiple points for mapping out the overall structural deformed shapes for visual display. The shape-prediction accuracies of the Improved Displacement Transfer Functions were then examined in view of finite-element-calculated deflections using different tapered cantilever tubular beams. It was found that by using the piecewise nonlinear strain representations, the shape-prediction accuracies could be greatly improved, especially for highly-tapered cantilever tubular beams.
Kanai, Y; Takeuchi, N
2009-10-14
We revisit the molecular line growth mechanism of styrene on the hydrogenated Si(001) 2x1 surface. In particular, we investigate the energetics of the radical chain reaction mechanism by means of diffusion quantum Monte Carlo (QMC) and density functional theory (DFT) calculations. For the exchange correlation (XC) functional we use the non-empirical generalized-gradient approximation (GGA) and meta-GGA. We find that the QMC result also predicts the intra dimer-row growth of the molecular line over the inter dimer-row growth, supporting the conclusion based on DFT results. However, the absolute magnitudes of the adsorption and reaction energies, and the heights of the energy barriers differ considerably between the QMC and DFT with the GGA/meta-GGA XC functionals.
Geerligs, Linda; Cam-Can; Henson, Richard N
2016-07-15
Studies of brain-wide functional connectivity or structural covariance typically use measures like the Pearson correlation coefficient, applied to data that have been averaged across voxels within regions of interest (ROIs). However, averaging across voxels may result in biased connectivity estimates when there is inhomogeneity within those ROIs, e.g., sub-regions that exhibit different patterns of functional connectivity or structural covariance. Here, we propose a new measure based on "distance correlation"; a test of multivariate dependence of high dimensional vectors, which allows for both linear and non-linear dependencies. We used simulations to show how distance correlation out-performs Pearson correlation in the face of inhomogeneous ROIs. To evaluate this new measure on real data, we use resting-state fMRI scans and T1 structural scans from 2 sessions on each of 214 participants from the Cambridge Centre for Ageing & Neuroscience (Cam-CAN) project. Pearson correlation and distance correlation showed similar average connectivity patterns, for both functional connectivity and structural covariance. Nevertheless, distance correlation was shown to be 1) more reliable across sessions, 2) more similar across participants, and 3) more robust to different sets of ROIs. Moreover, we found that the similarity between functional connectivity and structural covariance estimates was higher for distance correlation compared to Pearson correlation. We also explored the relative effects of different preprocessing options and motion artefacts on functional connectivity. Because distance correlation is easy to implement and fast to compute, it is a promising alternative to Pearson correlations for investigating ROI-based brain-wide connectivity patterns, for functional as well as structural data. PMID:27114055
NASA Astrophysics Data System (ADS)
Farlin, J.; Maloszewski, P.
2012-12-01
Baseflow recession analysis and groundwater dating have up to now developed as two distinct branches of hydrogeology and were used to solve entirely different problems. We show that by combining two classical models, namely Boussinesq's Equation describing spring baseflow recession and the exponential piston-flow model used in groundwater dating studies, the parameters describing the transit time distribution of an aquifer can be in some cases estimated to a far more accurate degree than with the latter alone. Under the assumption that the aquifer basis is sub-horizontal, the mean residence time of water in the saturated zone can be estimated from spring baseflow recession. This provides an independent estimate of groundwater residence time that can refine those obtained from tritium measurements. This approach is demonstrated in a case study predicting atrazine concentration trend in a series of springs draining the fractured-rock aquifer known as the Luxembourg Sandstone. A transport model calibrated on tritium measurements alone predicted different times to trend reversal following the nationwide ban on atrazine in 2005 with different rates of decrease. For some of the springs, the best agreement between observed and predicted time of trend reversal was reached for the model calibrated using both tritium measurements and the recession of spring discharge during the dry season. The agreement between predicted and observed values was however poorer for the springs displaying the most gentle recessions, possibly indicating the stronger influence of continuous groundwater recharge during the dry period.
NASA Astrophysics Data System (ADS)
Farlin, J.; Maloszewski, P.
2013-05-01
Baseflow recession analysis and groundwater dating have up to now developed as two distinct branches of hydrogeology and have been used to solve entirely different problems. We show that by combining two classical models, namely the Boussinesq equation describing spring baseflow recession, and the exponential piston-flow model used in groundwater dating studies, the parameters describing the transit time distribution of an aquifer can be in some cases estimated to a far more accurate degree than with the latter alone. Under the assumption that the aquifer basis is sub-horizontal, the mean transit time of water in the saturated zone can be estimated from spring baseflow recession. This provides an independent estimate of groundwater transit time that can refine those obtained from tritium measurements. The approach is illustrated in a case study predicting atrazine concentration trend in a series of springs draining the fractured-rock aquifer known as the Luxembourg Sandstone. A transport model calibrated on tritium measurements alone predicted different times to trend reversal following the nationwide ban on atrazine in 2005 with different rates of decrease. For some of the springs, the actual time of trend reversal and the rate of change agreed extremely well with the model calibrated using both tritium measurements and the recession of spring discharge during the dry season. The agreement between predicted and observed values was however poorer for the springs displaying the most gentle recessions, possibly indicating a stronger influence of continuous groundwater recharge during the summer months.
NASA Technical Reports Server (NTRS)
Choi, Taeyong; Xiong, Xiaoxiong; Wang, Zhipeng
2013-01-01
Spatial quality of an imaging sensor can be estimated by evaluating its modulation transfer function (MTF) from many different sources such as a sharp edge, a pulse target, or bar patterns with different spatial frequencies. These well-defined targets are frequently used for prelaunch laboratory tests, providing very reliable and accurate MTF measurements. A laboratory-quality edge input source was included in the spatial-mode operation of the Spectroradiometric Calibration Assembly (SRCA), which is one of the onboard calibrators of the Moderate Resolution Imaging Spectroradiometer (MODIS). Since not all imaging satellites have such an instrument, SRCA MTF estimations can be used as a reference for an on-orbit lunar MTF algorithm and results. In this paper, the prelaunch spatial quality characterization process from the Integrated Alignment Collimator and SRCA is briefly discussed. Based on prelaunch MTF calibration using the SRCA, a lunar MTF algorithm is developed and applied to the lifetime on-orbit Terra and Aqua MODIS lunar collections. In each lunar collection, multiple scan-directionMoon-to-background transition profiles are aligned by the subpixel edge locations from a parametric Fermi function fit. Corresponding accumulated edge profiles are filtered and interpolated to obtain the edge spread function (ESF). The MTF is calculated by applying a Fourier transformation on the line spread function through a simple differentiation of the ESF. The lifetime lunar MTF results are analyzed and filtered by a relationship with the Sun-Earth-MODIS angle. Finally, the filtered lunarMTF values are compared to the SRCA MTF results. This comparison provides the level of accuracy for on-orbit MTF estimations validated through prelaunch SRCA measurements. The lunar MTF values had larger uncertainty than the SRCA MTF results; however, the ratio mean of lunarMTF fit and SRCA MTF values is within 2% in the 250- and 500-m bands. Based on the MTF measurement uncertainty range
Lee, Seong Kyu; Yang, Jae Won; Kim, Hyun Ho; Jo, Sae Byeok; Kang, Boseok; Bong, Hyojin; Lee, Hyo Chan; Lee, Geunsik; Kim, Kwang S; Cho, Kilwon
2014-08-26
The polymer-supported transfer of chemical vapor deposition (CVD)-grown graphene provides large-area and high-quality graphene on a target substrate; however, the polymer and organic solvent residues left by the transfer process hinder the application of CVD-grown graphene in electronic and photonic devices. Here, we describe an inverse transfer method (ITM) that permits the simultaneous transfer and doping of graphene without generating undesirable residues by using polymers with different functional groups. Unlike conventional wet transfer methods, the polymer supporting layer used in the ITM serves as a graphene doping layer placed at the interface between the graphene and the substrate. Polymers bearing functional groups can induce n-doping or p-doping into the graphene depending on the electron-donating or -withdrawing characteristics of functional groups. Theoretical models of dipole layer-induced graphene doping offered insights into the experimentally measured change in the work function and the Dirac point of the graphene. Finally, the electrical properties of pentacene field effect transistors prepared using graphene electrodes could be enhanced by employing the ITM to introduce a polymer layer that tuned the work function of graphene. The versatility of polymer functional groups suggests that the method developed here will provide valuable routes to the development of applications of CVD-grown graphene in organic electronic devices. PMID:25050634
The modulation transfer function of an optical coherence tomography imaging system in turbid media
NASA Astrophysics Data System (ADS)
Woolliams, P. D.; Tomlins, P. H.
2011-05-01
In this paper we describe measurements of the contrast transfer function, modulation transfer function and point-spread function of an optical coherence tomography (OCT) imaging system through scattering layers having a dimension-less scattering depth over the range 0.2-6.9. The results were found to be insensitive to scattering density, indicating that these measurement parameters alone do not well characterize the practical imaging ability of an OCT instrument. Attenuation and increased noise floor due to optical scattering were found to be the primary imaging limit and the effect of multiple scattering on OCT resolution was negligible.
Determination of the transfer function for optical surface topography measuring instruments—a review
NASA Astrophysics Data System (ADS)
Foreman, Matthew R.; Giusca, Claudiu L.; Coupland, Jeremy M.; Török, Peter; Leach, Richard K.
2013-05-01
A significant number of areal surface topography measuring instruments, largely based on optical techniques, are commercially available. However, implementation of optical instrumentation into production is currently difficult due to the lack of understanding of the complex interaction between the light and the component surface. Studying the optical transfer function of the instrument can help address this issue. Here a review is given of techniques for the measurement of optical transfer functions. Starting from the basis of a spatially coherent, monochromatic confocal scanning imaging system, the theory of optical transfer functions in three-dimensional (3D) imaging is presented. Further generalizations are reviewed allowing the extension of the theory to the description of conventional and interferometric 3D imaging systems. Polychromatic transfer functions and surface topography measurements are also discussed. Following presentation of theoretical results, experimental methods to measure the optical transfer function of each class of system are presented, with a focus on suitable methods for the establishment of calibration standards in 3D imaging and surface topography measurements.
Flexor carpi ulnaris transfer for radial nerve palsy: functional testing of long-term results.
Raskin, K B; Wilgis, E F
1995-09-01
Controversy persists over the use of the flexor carpi ulnaris for transfer to the extensor digitorum communis in the treatment of radial nerve palsy. Six patients with complete, irreparable radial nerve palsies were treated in part with the flexor carpi ulnaris to extensor digitorum communis tendon transfer (standard transfers: pronator teres to extensor carpi radialis brevis, flexor carpi ulnaris to extensor digitorum communis, and palmaris longus to the rerouted extensor pollicis longus) and were functionally tested for long-term results. The average follow-up time was 8 years (range, 3-15). A control group was comprised of 10 volunteers of similar demographics. This study evaluates the long-term functional recovery in three categories: range of motion, dynamic power of wrist motion, and functional ability as determined by work simulation techniques. The activities simulated were swinging a hammer, sawing wood, tightening screws, and using pliers. A functional range of motion was maintained in all patients, and the power of wrist motion was sufficient to perform all activities of daily living. The work simulation testing revealed no significant difference between the tendon transfer patients and control group with respect to hand dominance and normal variance. All patients were able to perform the simulated work with the same variance in power as the control group. Despite the obvious anatomic loss, wrist function is not significantly impaired after flexor carpi ulnaris tendon transfer for radial nerve palsy. PMID:8522738
Modulation transfer function measurements of QWIP and superlattice focal plane arrays
NASA Astrophysics Data System (ADS)
Gunapala, S. D.; Ting, D. Z.; Rafol, S. B.; Soibel, A.; Khoshakhlagh, A.; Hill, C.; Liu, J. K.; Mumolo, J. M.; Keo, S. A.
2013-01-01
Modulation transfer function (MTF) is the ability of an imaging system to faithfully image a given object. The MTF of an imaging system quantifies the ability of the system to resolve or transfer spatial frequencies. In this presentation we will discuss the detail MTF measurements of 1024x1024 pixels multi-band quantum well infrared photodetector and 320x256 pixels long-wavelength InAs/GaSb superlattice infrared focal plane arrays.
NASA Astrophysics Data System (ADS)
Li, Yuan; Wang, Mingjun; Wang, Huilin; Tan, Hao; Zhang, Ziding; Webb, Geoffrey I.; Song, Jiangning
2014-07-01
Lysine acetylation is a reversible post-translational modification, playing an important role in cytokine signaling, transcriptional regulation, and apoptosis. To fully understand acetylation mechanisms, identification of substrates and specific acetylation sites is crucial. Experimental identification is often time-consuming and expensive. Alternative bioinformatics methods are cost-effective and can be used in a high-throughput manner to generate relatively precise predictions. Here we develop a method termed as SSPKA for species-specific lysine acetylation prediction, using random forest classifiers that combine sequence-derived and functional features with two-step feature selection. Feature importance analysis indicates functional features, applied for lysine acetylation site prediction for the first time, significantly improve the predictive performance. We apply the SSPKA model to screen the entire human proteome and identify many high-confidence putative substrates that are not previously identified. The results along with the implemented Java tool, serve as useful resources to elucidate the mechanism of lysine acetylation and facilitate hypothesis-driven experimental design and validation.
Nakashima, Hiroyuki; Nakatsuji, Hiroshi
2008-12-12
The local energy defined by Hpsi/psi must be equal to the exact energy E at any coordinate of an atom or molecule, as long as the psi under consideration is exact. The discrepancy from E of this quantity is a stringent test of the accuracy of the calculated wave function. The H-square error for a normalized psi, defined by sigma2 identical with psi|(H-E)2|psi, is also a severe test of the accuracy. Using these quantities, we have examined the accuracy of our wave function of a helium atom calculated using the free complement method that was developed to solve the Schrödinger equation. Together with the variational upper bound, the lower bound of the exact energy calculated using a modified Temple's formula ensured the definitely correct value of the helium fixed-nucleus ground state energy to be -2.903,724,377,034,119,598,311,159,245, 194,4 a.u., which is correct to 32 digits. PMID:19113607
NASA Astrophysics Data System (ADS)
Bačić, Z.; Kress, J. D.; Parker, G. A.; Pack, R. T.
1990-02-01
Accurate 3D coupled channel calculations for total angular momentum J=0 for the reaction F+H2→HF+H using a realistic potential energy surface are analyzed. The reactive scattering is formulated using the hyperspherical (APH) coordinates of Pack and Parker. The adiabatic basis functions are generated quite efficiently using the discrete variable representation method. Reaction probabilities for relative collision energies of up to 17.4 kcal/mol are presented. To aid in the interpretation of the resonances and quantum structure observed in the calculated reaction probabilities, we analyze the phases of the S matrix transition elements, Argand diagrams, time delays and eigenlifetimes of the collision lifetime matrix. Collinear (1D) and reduced dimensional 3D bending corrected rotating linear model (BCRLM) calculations are presented and compared with the accurate 3D calculations.
On-orbit Modulation Transfer Function (MTF) Measurements for IKONOS and QuickBird
NASA Technical Reports Server (NTRS)
Helde, Dennis; Choi, Jason; Anderson, Cody
2007-01-01
Point Spread Function is a method of evaluation the spatial resolution of an imaging system. It is also a measure of the spread of a single point of light. Modulation Transfer Function (MTF) is a measure of the spatial frequency response. It is often calculated from th point spread function (PSF). System response at the Nyquist frequency (or 0.5 cycle/pixel) is often used as a figure of merit
Cantaluppi, Vincenzo; Dellepiane, Sergio; Tamagnone, Michela; Medica, Davide; Figliolini, Federico; Messina, Maria; Manzione, Ana Maria; Gai, Massimo; Tognarelli, Giuliana; Ranghino, Andrea; Dolla, Caterina; Ferrario, Silvia; Tetta, Ciro; Segoloni, Giuseppe Paolo; Camussi, Giovanni; Biancone, Luigi
2015-01-01
Background Delayed graft function (DGF) is an early complication of kidney transplantation (KT) associated with increased risk of early loss of graft function. DGF increases using kidneys from extended criteria donors (ECD). NGAL is a 25KDa protein proposed as biomarker of acute kidney injury. The aim of this study was to investigate the role of NGAL as an early and accurate indicator of DGF and Tacrolimus (Tac) toxicity and as a mediator of tissue regeneration in KT from ECD. Methods We evaluated plasma levels of NGAL in 50 KT patients from ECD in the first 4 days after surgery or after Tac introduction. Results Plasma levels of NGAL at day 1 were significantly higher in DGF group. In the non DGF group, NGAL discriminated between slow or immediate graft function and decreased more rapidly than serum creatinine. NGAL increased after Tac introduction, suggesting a role as marker of drug toxicity. In vitro, hypoxia and Tac induced NGAL release from tubular epithelial cells (TEC) favoring an autocrine loop that sustains proliferation and inhibits apoptosis (decrease of caspases and Bax/Bcl-2 ratio). Conclusions NGAL is an early and accurate biomarker of graft function in KT from ECD favoring TEC regeneration after ischemic and nephrotoxic injury. PMID:26125566
Effect of Higher-Order Spherical Aberration Term on Transfer Function in Electron Microscopy
NASA Astrophysics Data System (ADS)
Uchida, Yuji; Fujimoto, Fuminori
1986-04-01
The effect of the higher-order spherical aberration coefficient on the transfer function in transmission electron microscopy was calculated. In order to simplify the system, the optical illumination system was assumed to be perfectly coherent and axially symmetric. The result shows that the effect of the fifth-order spherical aberration coefficient, C5, on the usual transfer function with the third-order spherical aberration coefficient Cs\\equivC3{=}0.5 mm for 100 keV electrons cannot be neglected, if high-order Bragg reflections from net planes with smaller lattice spacings than 0.1 nm are utilized for lattice imaging. The effect of the higher-order term due to the defocussing on the transfer function is also discussed.
Obtaining the Transfer Function of optical instruments using large calibrated reference objects.
Henning, A J; Huntley, J M; Giusca, C L
2015-06-29
It has been suggested recently that the Transfer Function of instruments such as Coherence Scanning Interferometers could be measured via a single measurement of a large spherical artefact [Appl. Opt.53(8), 1554-1563 (2014)]. In the current paper we present analytical solutions for the Fourier transform of the 'foil' model used in this technique, which thus avoids the artefacts resulting from the numerical approach used earlier. The Fourier transform of a partial spherical shell is found to contain points of zero amplitude for spatial frequencies that lie within the Transfer Function. This implies that the Transfer Function is unmeasurable at these points when a single spherical artefact is used, in situations where the foil model is a valid representation of the physical system. We propose extensions to the method to address this issue. PMID:26191674
Linear and nonlinear transfer functions of single mode fiber for optical transmission systems.
Binh, Le Nguyen
2009-07-01
The transmittance transfer function of single mode optical fibers operating in both linear and nonlinear regions is presented. For the linear domain, Fresnel sine and cosine integrals are obtained via the Fourier transform. In the nonlinear region dominated by self-phase-modulation effects, the Volterra series is essential to obtain the nonlinear transfer function. A convergence criterion for the Volterra series transfer function (VSTF) approach is described for solving the nonlinear Schrödinger wave propagation equation. Soliton transmission over single fibers is demonstrated as a case study of the application of the VSTF and a modified VSTF with a number of segmented steps whose distance is within the limit of the convergence of the VSTF. PMID:19568291
NASA Astrophysics Data System (ADS)
Bruntz, R. J.; Paxton, L. J.; Miller, E. S.; Bust, G. S.; Mayr, H. G.
2015-12-01
The Transfer Function Model (TFM) has been used in numerous studies to simulate gravity waves. In the TFM, the time dependence is formulated in terms of frequencies, and the horizontal wave pattern on the globe is formulated in terms of vector spherical harmonics. For a wide range of frequencies, the equations of mass, energy and momentum conservation are solved to compile a transfer function. The transfer function can then be easily combined with a time-dependent source whose spatial extent is also expressed in spherical harmonics, to produce a global atmospheric response, including gravity waves. This approach has significant benefits in that the solution is grid-independent (without any inherent limits on resolution), and the solutions do not suffer from singularities at the poles. We will show results from our simulations that couple the output of the TFM to an ionospheric model, to predict traveling ionospheric disturbances (TIDs) driven by the simulated gravity waves.
The Mid-Term Changes of Pulmonary Function Tests After Phrenic Nerve Transfer
Yavari, Masoud; Hassanpour, Seyed Esmail; Khodayari, Mohammad
2016-01-01
Background: In the restoration of elbow flexion, the phrenic nerve has proven to be a good donor, but considering the role of the phrenic nerve in respiratory function, we cannot disregard the potential dangers of this method. Objectives: In the current study, we reviewed the results of pulmonary function tests (PFT) in four patients who underwent phrenic nerve transfer. Patients and Methods: We reviewed the results of serial spirometry tests, which were performed before and after phrenic nerve transfer surgery. Results: All patients regained Biceps power to M3 strength or above. None of our patients experienced pulmonary problems or respiratory complaints, but a significant reduction of spirometric parameters occurred after surgery. Conclusions: This study highlights the close link between the role of the phrenic nerve and pulmonary function, such that the use of this nerve as a transfer donor leads to spirometric impairments. PMID:27148498
Swamy, Gokul; Xu, Da; Olivier, N Bari; Mukkamala, Ramakrishna
2009-11-01
We developed a new technique to mathematically transform a peripheral artery pressure (PAP) waveform distorted by wave reflections into the physiologically more relevant aortic pressure (AP) waveform. First, a transfer function relating PAP to AP is defined in terms of the unknown parameters of a parallel tube model of pressure and flow in the arterial tree. The parameters are then estimated from the measured PAP waveform along with a one-time measurement of the wave propagation delay time between the aorta and peripheral artery measurement site (which may be accomplished noninvasively) by exploiting preknowledge of aortic flow. Finally, the transfer function with its estimated parameters is applied to the measured waveform so as to derive the AP waveform. Thus, in contrast to the conventional generalized transfer function, the transfer function is able to adapt to the intersubject and temporal variability of the arterial tree. To demonstrate the feasibility of this adaptive transfer function technique, we performed experiments in 6 healthy dogs in which PAP and reference AP waveforms were simultaneously recorded during 12 different hemodynamic interventions. The AP waveforms derived by the technique showed agreement with the measured AP waveforms (overall total waveform, systolic pressure, and pulse pressure root mean square errors of 3.7, 4.3, and 3.4 mmHg, respectively) statistically superior to the unprocessed PAP waveforms (corresponding errors of 8.6, 17.1, and 20.3 mmHg) and the AP waveforms derived by two previously proposed transfer functions developed with a subset of the same canine data (corresponding errors of, on average, 5.0, 6.3, and 6.7 mmHg). PMID:19783780
NASA Astrophysics Data System (ADS)
Chen, Hanghui; Millis, Andrew J.
2016-05-01
We systematically compare predictions of various exchange correlation functionals for the structural and magnetic properties of perovskite Sr1 -xBaxMnO3 (0 ≤x ≤1 )—a representative class of multiferroic oxides. The local spin density approximation (LSDA) and spin-dependent generalized gradient approximation with Perdew-Burke-Ernzerhof parametrization (sPBE) make substantial different predictions for ferroelectric atomic distortions, tetragonality, and ground state magnetic ordering. Neither approximation quantitatively reproduces all the measured structural and magnetic properties of perovskite Sr0.5Ba0.5MnO3 . The spin-dependent generalized gradient approximation with Perdew-Burke-Ernzerhof revised for solids parametrization (sPBEsol) and the charge-only Perdew-Burke-Ernzerhof parametrized generalized gradient approximation with Hubbard U and Hund's J extensions both provide overall better agreement with measured structural and magnetic properties of Sr0.5Ba0.5MnO3 , compared to LSDA and sPBE. Using these two methods, we find that different from previous predictions, perovskite BaMnO3 has large Mn off-center displacements and is close to a ferromagnetic-to-antiferromagnetic phase boundary, making it a promising candidate to induce effective giant magnetoelectric effects and to achieve cross-field control of polarization and magnetism.
NASA Astrophysics Data System (ADS)
Ohtsubo, J.
1985-05-01
The normal model of light propagation through a turbulent atmosphere is used to investigate the telescope-atmosphere transfer function in stellar speckle interferometry. The effect of the finite bandwidth of a spectral filter on the transfer function is considered. The permissible focusing errors for successful processing in stellar speckle interferometry are obtained based on the normal model. Some observational results are presented and compared with theory. The normal model leads to an analytically simple solution and properly describes light scattering from turbulent atmosphere. The results for the normal model are compared with those for the log-normal model.
Liu, Siyu; Zhao, Ning; Cheng, Zhen; Liu, Hongguang
2015-04-21
Amino-functionalized fluorescent carbon dots have been prepared by hydrothermal treatment of glucosamine with excess pyrophosphate. The produced carbon dots showed stabilized green emission fluorescence at various excitation wavelengths and pH environments. Herein, we demonstrate the surface energy transfer between the amino-functionalized carbon dots and negatively charged hyaluronate stabilized gold nanoparticles. Hyaluronidase can degrade hyaluronate and break down the hyaluronate stabilized gold nanoparticles to inhibit the surface energy transfer. The developed fluorescent carbon dot/gold nanoparticle system can be utilized as a biosensor for sensitive and selective detection of hyaluronidase by two modes which include fluorescence measurements and colorimetric analysis. PMID:25807038
NASA Technical Reports Server (NTRS)
Chen, M. H.; Berger, R. D.; Saul, J. P.; Stevenson, K.; Cohen, R. J.
1987-01-01
We report a new method for the noninvasive characterization of the frequency response of the autonomic nervous system (ANS) in mediating fluctuations in heart rate (HR). The approach entails computation of the transfer function magnitude and phase between instantaneous lung volume and HR. Broad band fluctuations in lung volume were initiated when subjects breathed on cue to a sequence of beeps spaced randomly in time. We studied 10 subjects in both supine and standing positions. The transfer function, averaged among all the subjects, showed systematic differences between the two postures, reflecting the differing frequency responses of the sympathetic and parasympathetic divisions of the ANS.
An accurate cluster selection function for the J-PAS narrow-band wide-field survey
NASA Astrophysics Data System (ADS)
Ascaso, B.; Benítez, N.; Dupke, R.; Cypriano, E.; Lima-Neto, G.; López-Sanjuan, C.; Varela, J.; Alcaniz, J. S.; Broadhurst, T.; Cenarro, A. J.; Devi, N. Chandrachani; Díaz-García, L. A.; Fernandes, C. A. C.; Hernández-Monteagudo, C.; Mei, S.; Mendes de Oliveira, C.; Molino, A.; Oteo, I.; Schoenell, W.; Sodré, L.; Viironen, K.; Marín-Franch, A.
2016-03-01
The impending Javalambre Physics of the accelerating Universe Astrophysical Survey (J-PAS) will be the first wide-field survey of ≳ 8500 deg2 to reach the `stage IV' category. Because of the redshift resolution afforded by 54 narrow-band filters, J-PAS is particularly suitable for cluster detection in the range z<1. The photometric redshift dispersion is estimated to be only ˜0.003 with few outliers ≲4 per cent for galaxies brighter than i ˜ 23 AB, because of the sensitivity of narrow band imaging to absorption and emission lines. Here, we evaluate the cluster selection function for J-PAS using N-body+semi-analytical realistic mock catalogues. We optimally detect clusters from this simulation with the Bayesian Cluster Finder, and we assess the completeness and purity of cluster detection against the mock data. The minimum halo mass threshold we find for detections of galaxy clusters and groups with both >80 per cent completeness and purity is Mh ˜ 5 × 1013 M⊙ up to z ˜ 0.7. We also model the optical observable, M^{*}_CL-halo mass relation, finding a non-evolution with redshift and main scatter of σ _{M^{*}_CL | M_h}˜ 0.14 dex down to a factor 2 lower in mass than other planned broad-band stage IV surveys, at least. For the Mh ˜ 1 × 1014 M⊙ Planck mass limit, J-PAS will arrive up to z ˜ 0.85 with a σ _{M^{*}_CL | M_h}˜ 0.12 dex. Therefore, J-PAS will provide the largest sample of clusters and groups up to z ˜ 0.8 with a mass calibration accuracy comparable to X-ray data.
The route to MBxNyCz molecular wheels: II. Results using accurate functionals and basis sets
NASA Astrophysics Data System (ADS)
Güthler, A.; Mukhopadhyay, S.; Pandey, R.; Boustani, I.
2014-04-01
Applying ab initio quantum chemical methods, molecular wheels composed of metal and light atoms were investigated. High quality basis sets 6-31G*, TZPV, and cc-pVTZ as well as exchange and non-local correlation functionals B3LYP, BP86 and B3P86 were used. The ground-state energy and structures of cyclic planar and pyramidal clusters TiBn (for n = 3-10) were computed. In addition, the relative stability and electronic structures of molecular wheels TiBxNyCz (for x, y, z = 0-10) and MBnC10-n (for n = 2 to 5 and M = Sc to Zn) were determined. This paper sustains a follow-up study to the previous one of Boustani and Pandey [Solid State Sci. 14 (2012) 1591], in which the calculations were carried out at the HF-SCF/STO3G/6-31G level of theory to determine the initial stability and properties. The results show that there is a competition between the 2D planar and the 3D pyramidal TiBn clusters (for n = 3-8). Different isomers of TiB10 clusters were also studied and a structural transition of 3D-isomer into 2D-wheel is presented. Substitution boron in TiB10 by carbon or/and nitrogen atoms enhances the stability and leads toward the most stable wheel TiB3C7. Furthermore, the computations show that Sc, Ti and V at the center of the molecular wheels are energetically favored over other transition metal atoms of the first row.
NASA Astrophysics Data System (ADS)
de Natale, Giuseppe; Crippa, Bruno; Troise, Claudia; Pingue, Folco; Audia, Karim; Dalla Via, Giorgio
2010-05-01
The seismic sequence occurred in the Abruzzo Apennines near L'Aquila (Italy) in April 2009 caused extensive damage and a large number of casualties (close to 300). The earthquake struck an area in the Italian Apennines chain where several faults, belonging to adjacent seismotectonic domains, create a complex tectonic regime resulting from the interaction among regional stress build-up, local stress changes caused by individual earthquakes and visco-elastic stress relaxation. Understanding such complex interaction in the Apennines can lead to a large step forward in the seismic risk mitigation in Italy. The Abruzzo earthquake has been exceptionally well recorded by InSAR data, much better than the first Italian earthquake ever recorded by satellites, namely the 1997 Umbria-Marche one. Envisat data for the Abruzzo earthquake are in fact very clear and allow an accurate reconstruction of the faulting mechanism. We present here an accurate inversion of vertical deformation data obtained by ENVISAT images, aimed to give a detailed reconstruction of the fault geometry and slip distribution. The resulting faulting models are then used to compute, by a suitable theoretical model based on elastic dislocation theory, the stress changes induced on the neighbouring faults. The study of the subsequent mainshocks of the Abruzzo sequence clearly evidence the effect of static stress changes consecutively triggering the subsequent mainshocks. Furthermore, this analysis put in evidence the seismotectonic domains that have been more heavily charged by stress released by the Abruzzo mainshocks. The most important faults significantly charged by the Abruzzo sequence include the Sulmona and Avezzano tectonic domains, including also the area, West-Southwest to the Avezzano domain, where a large earthquake occurred in 1394. Taking into account the average regional stress build-up in the area, the positive Coulomb stress changes caused by this earthquake can be seen as anticipating the
Dynamics of charge transfer: Rate processes formulated with nonequilibrium Green's functions
Yeganeh, Sina; Ratner, Mark A.; Mujica, Vladimiro
2007-04-28
The authors examine the connection between electron transport under bias in a junction and nonadiabatic intramolecular electron transfer (ET). It is shown that under certain assumptions it is possible to define a stationary current that allows the computation of the intramolecular transfer rate using the same formalism that is employed in the description of transport. They show that the nonequilibrium Green's function formalism of quantum transport can be used to calculate the ET rate. The formal connection between electron transport and electron transfer is made, and they work out the simple case of an electronic level coupled to a vibrational mode representing a thermal bath and show that the result is the same as expected from a Fermi golden rule treatment, and in the high-temperature limit yields the Marcus electron transfer theory. The usefulness of this alternative formulation of rates is discussed.
Functional evaluation of the hand and foot after one-stage toe-to-hand transfer.
Frykman, G K; O'Brien, B M; Morrison, W A; MacLeod, A M
1986-01-01
Twenty toe-to-hand transfers in 17 patients with an average follow-up of 54 months have been reviewed to quantify hand function and donor morbidity. Eleven toe-to-thumb and nine toe-to-finger procedures were performed. Surgical and follow-up data were available for all patients. Twelve patients (14 procedures) were reviewed in detail, with particular attention given to foot and hand function. Total active motion after toe-to-thumb transfer was 48 degrees and 106 degrees after toe-to-finger transfer. Two-point discrimination was less than or equal to 15 mm in 13 digits (65%). Grip and pinch power were related to the number of digits present on the reconstructed hand and to the presence or absence of functioning thenar muscles. Eleven of 12 patients can walk and run normally (mean of 5 years after surgery). Six (50%) cannot wear thongs or heavy boots, but all can wear normal shoes. The transferred great toe decreased in volume by an average of 10% over the years since the operation. Transferred toes became useful digits in the hand, and foot morbidity was minor and not progressive. PMID:3944453
Direct metal transfer printing on flexible substrate for fabricating optics functional devices
NASA Astrophysics Data System (ADS)
Jiang, Yingjie; Zhou, Xiaohong; Zhang, Feng; Shi, Zhenwu; Chen, Linsen; Peng, Changsi
2015-11-01
New functional materials and devices based on metal patterns can be widely used in many new and expanding industries,such as flat panel displays, alternative energy,sensors and so on. In this paper, we introduce a new transfer printing method for fabricating metal optics functional devices. This method can directly transfer a metal pattern from a polyethylene terephthalate (PET)supported UV or polydimethylsiloxane (PDMS) pattern to another PET substrate. Purely taking advantage of the anaerobic UV curing adhesive (a-UV) on PET substrate, metal film can be easily peeled off from micro/nano-structured surface. As a result, metal film on the protrusion can be selectively transferred onto the target substrate, to make it the metal functional surface. But which on the bottom can not be transferred. This method provides low cost fabrication of metal thin film devices by avoiding high cost lithography process. Compared with conventional approach, this method can get more smooth rough edges and has wider tolerance range for the original master mold. Future developments and potential applications of this metal transfer method will be addressed.
Transfer function approach for artificial tracer test interpretation in karstic systems
NASA Astrophysics Data System (ADS)
Labat, D.; Mangin, A.
2015-10-01
A karstic formation consists in a three-dimensional hydrological system which involves horizontal and vertical, diphasic or saturated water transfers characterised by a large range of velocity. These subsurface flow processes correspond to various water pathways through fractured, fissured, and underground streams or conduits leading to a nonlinear global behaviour of the system. An efficient way of investigating of a karstic system behaviour consists in the injection of artificial tracer tests at loss points and in careful analysis of the recovery tracer fluxes at one or several outlets of the systems. These injections are also an efficient way of providing hypotheses on characteristic time of contaminant transfer in these type of aquifers. Here, we propose a Laplace-transform transfer function of the Residence Time Distribution function that allows to discriminate between a quick-flow advection-dominated component and a slow-flow advection-dispersion/dominated component in the artificial tracer transfer in the system. We apply this transfer function on five high resolution sampling rate artificial tracer tests operated on the Baget system in the Pyrenees (France) in order to illustrate the advantages and limitations of this approach. We provide then an interpretation of the relationship between tracer test recovery shape and karstic system organisation between inlet and outlet site.
NASA Astrophysics Data System (ADS)
Banbury, J. R.
1981-10-01
Cathode-ray tube evaluation is becoming increasingly important in connection with the prediction of overall performance for systems incorporating an imaging display. Modulation transfer function has been measured by a method which takes account of the basic non-linearities of the crt and also offers improved accuracy by reducing the effects of phosphor screen noise. Two tests for crt internal veiling glare are discussed. Standard test conditions, which have been successfully used for a wide range of displays are described for both mtf and veiling glare. A contrast index is employed to indicate the extent of nonlinearity in the display transfer characteristic, and the paper also discusses briefly the use of generalised drive characteristics and limiting contrast curves as a supplement or alternative to modulation transfer function for definition of display performance.
Structure and Function of Phosphatidylcholine transfer protein (PC-TP)/StarD2
Kanno,K.; Wu, M.; Scapa, E.; Roderick, S.; Cohen, D.
2007-01-01
Phosphatidylcholine transfer protein (PC-TP) is a highly specific soluble lipid binding protein that transfers phosphatidylcholine between membranes in vitro. PC-TP is a member of the steroidogenic acute regulatory protein-related transfer (START) domain superfamily. Although its biochemical properties and structure are well characterized, the functions of PC-TP in vivo remain incompletely understood. Studies of mice with homozygous disruption of the Pctp gene have largely refuted the hypotheses that this protein participates in the hepatocellular selection and transport of biliary phospholipids, in the production of lung surfactant, in leukotriene biosynthesis and in cellular phosphatidylcholine metabolism. Nevertheless, Pctp-/- mice exhibit interesting defects in lipid homeostasis, the understanding of which should elucidate the biological functions of PC-TP.
NASA Astrophysics Data System (ADS)
Elgohary, Tarek A.; Turner, James D.; Junkins, John L.
2015-06-01
A symmetric flexible rotating spacecraft can be modeled as a distributed parameter system of a rigid hub attached to two flexible appendages with tip masses. First, Hamilton's extended principle is utilized to establish a general treatment for deriving the dynamics of multi-body dynamical systems to establish a hybrid system of integro-partial differential equations that model the evolution of the system in space and time. A Generalized State Space (GSS) system of equations is constructed in the frequency domain to obtain analytic transfer functions for the rotating spacecraft. This model does not include spatial discretization. The frequency response of the generally modeled spacecraft and a special case with no tip masses are presented. Numerical results for the system frequency response obtained from the analytic transfer functions are presented and compared against the classical assumed modes numerical method with two choices of admissible functions. The truncation-error-free analytic results are used to validate the numerical approximations and to agree well with the classical widely used finite dimensional numerical solutions. Fundamentally, we show that the rigorous transfer function, without introduction of spatial discretization, can be directly used in control law design with a guarantee of Lyapunov stable closed loop dynamics. The frequency response of the system is used in a classical control problem where the Lyapunov stable controller is derived and tested for gain selection. The correlation between the controller design in the frequency domain utilizing the analytic transfer functions and the system response is analyzed and verified. The derived analytic transfer functions provide a powerful tool to test various control schemes in the frequency domain and a validation platform for existing numerical methods for distributed parameters models. The same platform has been used to obtain the frequency response of more complex beam models following
Back-illuminated CCD imager adapted for contrast transfer function measurements thereon
NASA Technical Reports Server (NTRS)
Levine, Peter A. (Inventor)
1987-01-01
Stripe patterns of varying spatial frequency, formed in the top-metalization of a back-illuminated solid-state imager, facilitate on-line measurement of contrast transfer function during wafer-probe testing. The imager may be packaged to allow front-illumination during in-the-field testing after its manufacture.
NASA Astrophysics Data System (ADS)
Simon, Emanuel; Foschum, Florian; Kienle, Alwin
2013-06-01
Time-resolved diffuse optical spectroscopy measurements of phantoms at small source-detector separations yield good results for the retrieved coefficients of reduced scattering and absorption when a hybrid Green's function of the radiative transfer equation for semi-infinite media is used.
5 CFR 351.303 - Identification of positions with a transferring function.
Code of Federal Regulations, 2011 CFR
2011-01-01
... SERVICE REGULATIONS REDUCTION IN FORCE Transfer of Function § 351.303 Identification of positions with a... agency may supplement the employee's official position description by the use of appropriate records (e.g... separation or demotion by reduction in force at the losing competitive area of any employee with...
5 CFR 351.303 - Identification of positions with a transferring function.
Code of Federal Regulations, 2013 CFR
2013-01-01
... SERVICE REGULATIONS REDUCTION IN FORCE Transfer of Function § 351.303 Identification of positions with a... agency may supplement the employee's official position description by the use of appropriate records (e.g... separation or demotion by reduction in force at the losing competitive area of any employee with...
Dual Nerve Transfers for Restoration of Shoulder Function After Brachial Plexus Avulsion Injury.
Chu, Bin; Wang, Huan; Chen, Liang; Gu, Yudong; Hu, Shaonan
2016-06-01
The purpose of this study was to investigate the effectiveness of shoulder function restoration by dual nerve transfers, spinal accessory nerve to the suprascapular nerve and 2 intercostal nerves to the anterior branch of the axillary nerve, in patients with shoulder paralysis that resulted from brachial plexus avulsion injury. It was a retrospective analysis to assess the impact of a variety of factors on reanimation of shoulder functions with dual nerve transfers. A total of 19 patients were included in this study. Most of these patients sustained avulsions of C5, C6, and C7 nerve roots (16 patients). Three of them had avulsions of C5 and C6 roots only. Through a posterior approach, direct coaptation of the intercostal nerves and the anterior branch of the axillary nerve was performed, along with accessory nerve transfer to the suprascapular nerve. Satisfactory shoulder function recovery (93.83° of shoulder abduction and 54.00° of external rotation on average) was achieved after a 62-month follow-up. This dual nerve transfer procedure provided us with a reliable and effective method for shoulder function reconstruction after brachial plexus root avulsion, especially C5/C6/C7 avulsion. The level of evidence is therapeutic IV. PMID:26835823
The Derived Transfer and Reversal of Mood Functions through Equivalence Relations: II
ERIC Educational Resources Information Center
Cahill, Jane; Barnes-Holmes, Yvonne; Barnes-Holmes, Dermot; Rodriguez-Valverde, Miguel; Luciano, Carmen; Smeets, Paul M.
2007-01-01
Recent research has demonstrated the transfer of induced mood functions through equivalence relations by means of a musical mood-induction procedure. The research described in this article replicated and extended such work, primarily with the inclusion of a baseline and two types of reversal procedures. First, 16 adult participants were trained…
Transfer functions of double- and multiple-cavity Fabry Perot filters driven by Lorentzian sources
NASA Astrophysics Data System (ADS)
Marti, Javier; Capmany, Jose
1996-12-01
We derive expressions for the transfer functions of double- and multiple-cavity Fabry Perot filters driven by laser sources with Lorentzian spectrum. These are of interest because of their applications in sensing and channel filtering in optical frequency-division multiplexing networks.
5 CFR 351.303 - Identification of positions with a transferring function.
Code of Federal Regulations, 2010 CFR
2010-01-01
... SERVICE REGULATIONS REDUCTION IN FORCE Transfer of Function § 351.303 Identification of positions with a... agency may supplement the employee's official position description by the use of appropriate records (e.g... separation or demotion by reduction in force at the losing competitive area of any employee with...
Functional outcomes of post-traumatic metacarpal hand reconstruction with free toe-to-hand transfer
Venkatramani, Hari; Bhardwaj, Praveen; Sierakowski, Adam; Sabapathy, S. Raja
2016-01-01
Introduction: We present the functional outcomes of microvascular toe transfer to reconstruct the post-traumatic metacarpal hand deformity. Twelve toe transfers were successfully carried out in 11 patients. Materials and Methods: In each patient, the level of injury was classified according to the Wei classification system. Functional outcome was measured in seven patients using the Tamai score. Additional objective tests of function were carried out in three patients, including the Jebsen test, grip strength, pinch strength, web opening, static and moving two-point discrimination and Semmes–Weinstein monofilament testing. Observation and Results: The average Tamai score was 69 (range 60–83.5). Six patients achieved ‘good’ outcomes and one patient, with a double toe transfer, an ‘excellent’ outcome. The average follow-up time was 43 months (range 10–148 months). Conclusion: This study shows how even a single toe transfer can restore useful function to a hand that has otherwise lost all prehensile ability. PMID:27274118
Modulation transfer function testing of detector arrays using narrow-band laser speckle
NASA Astrophysics Data System (ADS)
Sensiper, Martin; Boreman, Glenn D.; Ducharme, Alfred D.; Snyder, Donald R.
1993-02-01
A method for measuring the modulation transfer function (MTF) of a detector array from zero spatial frequency to twice the Nyquist frequency is presented. Laser speckle with a tunable, narrow spatial-frequency bandpass is used. The MTF measured with this method is compared to the MTF measured using sine targets. The results of the two methods agree to within 2%.
NASA Astrophysics Data System (ADS)
Nakamura, Takashi; Chang, Chang
2011-08-01
Performance of two types of differential interference contrast objectives, i.e., the XOR pattern and the zone-plate doublet, is quantitatively characterized and compared using modulation transfer function. Effects of partial coherence, finite absorption and phase in a complex object, as well as bias retardation are also examined.
Nakamura, Takashi; Chang, Chang
2011-08-01
Performance of two types of differential interference contrast objectives, i.e., the XOR pattern and the zone-plate doublet, is quantitatively characterized and compared using modulation transfer function. Effects of partial coherence, finite absorption and phase in a complex object, as well as bias retardation are also examined. PMID:21934894
ERIC Educational Resources Information Center
Pauen, Sabina; Bechtel-Kuehne, Sabrina
2016-01-01
This report investigates tool learning and its relations to executive functions (EFs) in toddlers. In Study 1 (N = 93), 18-, 20-, 22-, and 24-month-old children learned equally well to choose a correct tool from observation, whereas performance based on feedback improved with age. Knowledge transfer showed significant progress after 22 months of…
Moire modulation transfer function of alexandrite rods and their thresholds as lasers
Kafri, O.; Samelson, H.; Chin, T.; Heller, D.F.
1986-04-01
We show that there is a simple correlation between the modulation transfer function (MTF) of alexandrite laser rods and the thresholds of these rods as cw lasers. Thus the MTF provides a novel and important way to evaluate material (before or after fabrication) for use in solid-state lasers. This approach should be generally applicable to all solid-state laser materials.
ERIC Educational Resources Information Center
Fisher, Wayne W.; Greer, Brian D.; Fuhrman, Ashley M.; Querim, Angie C.
2015-01-01
Multiple schedules with signaled periods of reinforcement and extinction have been used to thin reinforcement schedules during functional communication training (FCT) to make the intervention more practical for parents and teachers. We evaluated whether these signals would also facilitate rapid transfer of treatment effects across settings and…
NASA Astrophysics Data System (ADS)
Liu, Siyu; Zhao, Ning; Cheng, Zhen; Liu, Hongguang
2015-04-01
Amino-functionalized fluorescent carbon dots have been prepared by hydrothermal treatment of glucosamine with excess pyrophosphate. The produced carbon dots showed stabilized green emission fluorescence at various excitation wavelengths and pH environments. Herein, we demonstrate the surface energy transfer between the amino-functionalized carbon dots and negatively charged hyaluronate stabilized gold nanoparticles. Hyaluronidase can degrade hyaluronate and break down the hyaluronate stabilized gold nanoparticles to inhibit the surface energy transfer. The developed fluorescent carbon dot/gold nanoparticle system can be utilized as a biosensor for sensitive and selective detection of hyaluronidase by two modes which include fluorescence measurements and colorimetric analysis.Amino-functionalized fluorescent carbon dots have been prepared by hydrothermal treatment of glucosamine with excess pyrophosphate. The produced carbon dots showed stabilized green emission fluorescence at various excitation wavelengths and pH environments. Herein, we demonstrate the surface energy transfer between the amino-functionalized carbon dots and negatively charged hyaluronate stabilized gold nanoparticles. Hyaluronidase can degrade hyaluronate and break down the hyaluronate stabilized gold nanoparticles to inhibit the surface energy transfer. The developed fluorescent carbon dot/gold nanoparticle system can be utilized as a biosensor for sensitive and selective detection of hyaluronidase by two modes which include fluorescence measurements and colorimetric analysis. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr00070j
Modulation Transfer Function (MTF) measurement techniques for lenses and linear detector arrays
NASA Technical Reports Server (NTRS)
Schnabel, J. J., Jr.; Kaishoven, J. E., Jr.; Tom, D.
1984-01-01
Application is the determination of the Modulation Transfer Function (MTF) for linear detector arrays. A system set up requires knowledge of the MTF of the imaging lens. Procedure for this measurement is described for standard optical lab equipment. Given this information, various possible approaches to MTF measurement for linear arrays is described. The knife edge method is then described in detail.
Logvinenko, A D
1990-01-01
The harmonic input method of nonlinear system identification is modified to allow the Volterra series approach to be used for psychophysical investigation of various aspects of human pattern vision in the spatial frequency domain. While it is well known that only one modulation transfer function provides a complete characterization of a linear system, a number of multidimensional transfer functions are needed to identify a nonlinear system. We have shown, that so far as the contrast sensitivity to sine-wave gratings may be used for an empirical estimate of the first-order modulation transfer function of the human visual system, the contrast sensitivity to difference harmonics may be used as an empirical estimate of the second-order modulation transfer function. A difference harmonic arises from a mixture of two sine-wave gratings resulting from the nonlinearity of the visual system. Difference harmonic, experienced as some periodic beatlike structure, may still be observed if frequencies of the component gratings are higher than the maximum visual acuity. The visibility of the low-frequency beatlike pattern produced by pairs of sine-wave gratings, which themselves are of spatial frequencies too high to be resolved, could be accounted for either by a difference frequency distortion product (Burton, 1973) or by a special beat detector (Derrington & Badcock, 1985). We found that increasing the contrast of one component grating may be compensated for by reducing the contrast of the other component grating, the beatlike pattern being at threshold. This is exactly what would be expected if the beatlike pattern is detected because of the difference harmonics produced by nonlinearity of the visual system. We have determined contrast thresholds for the difference harmonics which occur between two unresolved different spatial frequencies. The contrast sensitivity function for difference harmonics was found to have a marked similarity both in the shape and position of peak
Boone, J M; Arnold, B A; Seibert, J A
1986-01-01
A digital radiographic system was used to measure the distribution of scattered x radiation from uniform slabs of Lucite at various thicknesses. Using collimation and air gap techniques, [primary + scatter] images and primary images were digitally acquired, and subtracted to obtain scatter images. The scatter distributions measured using small circular apertures were computer fit to an analytical function, representing the circular aperture function convolved with a modified Gaussian point spread function (PSF). On the basis of goodness of fit criterion, the proposed Gaussian function is a very good model for the scatter PSF. The measured scatter PSF's are reported for various Lucite thicknesses. Using the PSF's, the modulation transfer functions are calculated, and this spatial frequency information may have value in analytical scatter removal techniques, grid design, and air gap optimization. PMID:3702823
NASA Astrophysics Data System (ADS)
Boyd, John P.
2011-02-01
Radial basis function (RBF) interpolants have become popular in computer graphics, neural networks and for solving partial differential equations in many fields of science and engineering. In this article, we compare five different species of RBFs: Gaussians, hyperbolic secant (sech's), inverse quadratics, multiquadrics and inverse multiquadrics. We show that the corresponding cardinal functions for a uniform, unbounded grid are all approximated by the same function: C(X) ∼ (1/(ρ)) sin (πX)/sinh (πX/ρ) for some constant ρ(α) which depends on the inverse width parameter (“shape parameter”) α of the RBF and also on the RBF species. The error in this approximation is exponentially small in 1/α for sech's and inverse quadratics and exponentially small in 1/α2 for Gaussians; the error is proportional to α4 for multiquadrics and inverse multiquadrics. The error in all cases is small even for α ∼ O(1). These results generalize to higher dimensions. The Gaussian RBF cardinal functions in any number of dimensions d are, without approximation, the tensor product of one dimensional Gaussian cardinal functions: Cd(x1,x2…,xd)=∏j=1dC(xj). For other RBF species, we show that the two-dimensional cardinal functions are well approximated by the products of one-dimensional cardinal functions; again the error goes to zero as α → 0. The near-identity of the cardinal functions implies that all five species of RBF interpolants are (almost) the same, despite the great differences in the RBF ϕ's themselves.
Isegawa, Miho; Gao, Jiali; Truhlar, Donald G.
2011-01-01
Molecular fragmentation algorithms provide a powerful approach to extending electronic structure methods to very large systems. Here we present a method for including charge transfer between molecular fragments in the explicit polarization (X-Pol) fragment method for calculating potential energy surfaces. In the conventional X-Pol method, the total charge of each fragment is preserved, and charge transfer between fragments is not allowed. The description of charge transfer is made possible by treating each fragment as an open system with respect to the number of electrons. To achieve this, we applied Mermin's finite temperature method to the X-Pol wave function. In the application of this method to X-Pol, the fragments are open systems that partially equilibrate their number of electrons through a quasithermodynamics electron reservoir. The number of electrons in a given fragment can take a fractional value, and the electrons of each fragment obey the Fermi–Dirac distribution. The equilibrium state for the electrons is determined by electronegativity equalization with conservation of the total number of electrons. The amount of charge transfer is controlled by re-interpreting the temperature parameter in the Fermi–Dirac distribution function as a coupling strength parameter. We determined this coupling parameter so as to reproduce the charge transfer energy obtained by block localized energy decomposition analysis. We apply the new method to ten systems, and we show that it can yield reasonable approximations to potential energy profiles, to charge transfer stabilization energies, and to the direction and amount of charge transferred. PMID:21895159
A model of head-related transfer functions based on a state-space analysis
NASA Astrophysics Data System (ADS)
Adams, Norman Herkamp
This dissertation develops and validates a novel state-space method for binaural auditory display. Binaural displays seek to immerse a listener in a 3D virtual auditory scene with a pair of headphones. The challenge for any binaural display is to compute the two signals to supply to the headphones. The present work considers a general framework capable of synthesizing a wide variety of auditory scenes. The framework models collections of head-related transfer functions (HRTFs) simultaneously. This framework improves the flexibility of contemporary displays, but it also compounds the steep computational cost of the display. The cost is reduced dramatically by formulating the collection of HRTFs in the state-space and employing order-reduction techniques to design efficient approximants. Order-reduction techniques based on the Hankel-operator are found to yield accurate low-cost approximants. However, the inter-aural time difference (ITD) of the HRTFs degrades the time-domain response of the approximants. Fortunately, this problem can be circumvented by employing a state-space architecture that allows the ITD to be modeled outside of the state-space. Accordingly, three state-space architectures are considered. Overall, a multiple-input, single-output (MISO) architecture yields the best compromise between performance and flexibility. The state-space approximants are evaluated both empirically and psychoacoustically. An array of truncated FIR filters is used as a pragmatic reference system for comparison. For a fixed cost bound, the state-space systems yield lower approximation error than FIR arrays for D>10, where D is the number of directions in the HRTF collection. A series of headphone listening tests are also performed to validate the state-space approach, and to estimate the minimum order N of indiscriminable approximants. For D = 50, the state-space systems yield order thresholds less than half those of the FIR arrays. Depending upon the stimulus uncertainty, a
Otón, Joaquín; Sorzano, Carlos Oscar S; Marabini, Roberto; Pereiro, Eva; Carazo, Jose M
2015-04-20
Soft X-ray tomography (SXT) is becoming a powerful imaging technique to analyze eukaryotic whole cells close to their native state. Central to the analysis of the quality of SXT 3D reconstruction is the estimation of the spatial resolution and Depth of Field of the X-ray microscope. In turn, the characterization of the Modulation Transfer Function (MTF) of the optical system is key to calculate both parameters. Consequently, in this work we introduce a fully automated technique to accurately estimate the transfer function of such an optical system. Our proposal is based on the preprocessing of the experimental images to obtain an estimate of the input pattern, followed by the analysis in Fourier space of multiple orders of a Siemens Star test sample, extending in this way its measured frequency range. PMID:25968993
Zhang, Chun; Tang, Conghui; Jiao, Ning
2012-05-01
Copper salts have been developed as versatile catalysts for oxidative coupling reactions in organic synthesis. During these processes, Cu-catalysts are often proposed to serve as a one-electron oxidant to promote the single-electron transfer process. Recently, the transition-metal catalyzed direct dehydrogenative transformation has attracted considerable attention. This tutorial review summarizes the recent advances in the copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process achieving C-C, C-N, C-O, C-halogen atoms, C-P, and N-N bond formation. PMID:22349590
Sadot, D.; Kitron, G.; Kitron, N.; Kopeika, N.S. . Dept. of Electrical and Computer Engineering)
1994-03-01
Atmospheric modulation transfer function (MTF) measurements carried out simultaneously in both thermal imaging atmospheric windows using both passive and actively heated targets are presented. Results indicate rather significant angular spatial frequency dependence of the MTF, in contradiction to the conventional approach, which assumes contrast transfer is atmospheric transmission only. A theoretical explanation is discussed, based on aerosol forward scattering and absorption effects, which is shown to be angular spatial frequency dependent and yields MTF results similar to those measured. This means that small details are blurred much more than large details by the atmosphere, thus also affecting target acquisition probabilities.
Efficient application of the spectrally integrated Voigt function to radiative transfer spectroscopy
NASA Astrophysics Data System (ADS)
Abrarov, Sanjar
We present a new application of the spectrally integrated Voigt function (SIVF) to the radiative transfer spectroscopy that enables computation of the spectral radiance and radiance at reduced spectral resolution. Applying a technique based on the Fourier expansion of the exponential multiplier we obtain the series approximations providing high-accuracy and rapid SIVF computation. In contrast to traditional line-by-line (LBL) radiative transfer models, the proposed SIVF algorithm prevents underestimation in the absorption coefficients and, therefore, preserves the radiant energy. LBL sample computations utilizing SIVF algorithm show the advantages of the proposed methodology in terms of the accuracy and computational speed.
Transfer function approach based on simulation results for the determination of pod curves
NASA Astrophysics Data System (ADS)
Demeyer, S.; Jenson, F.; Dominguez, N.; Iakovleva, E.
2012-05-01
POD curves estimations are based on statistical studies of empirical data which are obtained thru costly and time consuming experimental campaigns. Currently, cost reduction of POD trials is a major issue. A proposed solution is to replace some of the experimental data required to determine the POD with model based results. Following this idea, the concept of Model Assisted POD (MAPOD) has been introduced first in the US in 2004 through the constitution of the MAPOD working group. One approach to Model Assisted POD is based on a transfer function which uses empirical data and models to transfer POD measured for one specific application to another related application. The objective of this paper is to show how numerical simulations could help to determine such transfer functions. A practical implementation of the approach to a high frequency eddy current inspection for fatigue cracks is presented. Empirical data is available for the titanium alloy plates. A model based transfer function is used to assess a POD curve for the inspection of aluminum components.
Charge-transfer-directed radical substitution enables para-selective C-H functionalization.
Boursalian, Gregory B; Ham, Won Seok; Mazzotti, Anthony R; Ritter, Tobias
2016-08-01
Efficient C-H functionalization requires selectivity for specific C-H bonds. Progress has been made for directed aromatic substitution reactions to achieve ortho and meta selectivity, but a general strategy for para-selective C-H functionalization has remained elusive. Herein we introduce a previously unappreciated concept that enables nearly complete para selectivity. We propose that radicals with high electron affinity elicit arene-to-radical charge transfer in the transition state of radical addition, which is the factor primarily responsible for high positional selectivity. We demonstrate with a simple theoretical tool that the selectivity is predictable and show the utility of the concept through a direct synthesis of aryl piperazines. Our results contradict the notion, widely held by organic chemists, that radical aromatic substitution reactions are inherently unselective. The concept of radical substitution directed by charge transfer could serve as the basis for the development of new, highly selective C-H functionalization reactions. PMID:27442288
Charge-transfer-directed radical substitution enables para-selective C–H functionalization
NASA Astrophysics Data System (ADS)
Boursalian, Gregory B.; Ham, Won Seok; Mazzotti, Anthony R.; Ritter, Tobias
2016-08-01
Efficient C–H functionalization requires selectivity for specific C–H bonds. Progress has been made for directed aromatic substitution reactions to achieve ortho and meta selectivity, but a general strategy for para-selective C–H functionalization has remained elusive. Herein we introduce a previously unappreciated concept that enables nearly complete para selectivity. We propose that radicals with high electron affinity elicit arene-to-radical charge transfer in the transition state of radical addition, which is the factor primarily responsible for high positional selectivity. We demonstrate with a simple theoretical tool that the selectivity is predictable and show the utility of the concept through a direct synthesis of aryl piperazines. Our results contradict the notion, widely held by organic chemists, that radical aromatic substitution reactions are inherently unselective. The concept of radical substitution directed by charge transfer could serve as the basis for the development of new, highly selective C–H functionalization reactions.
Accurate monotone cubic interpolation
NASA Technical Reports Server (NTRS)
Huynh, Hung T.
1991-01-01
Monotone piecewise cubic interpolants are simple and effective. They are generally third-order accurate, except near strict local extrema where accuracy degenerates to second-order due to the monotonicity constraint. Algorithms for piecewise cubic interpolants, which preserve monotonicity as well as uniform third and fourth-order accuracy are presented. The gain of accuracy is obtained by relaxing the monotonicity constraint in a geometric framework in which the median function plays a crucial role.
YANG, C.; JIANG, W.; CHEN, D. -H.; ADIGA, U.; NG, E. G.; CHIU, W.
2009-01-01
Summary The three-dimensional reconstruction of macromolecules from two-dimensional single-particle electron images requires determination and correction of the contrast transfer function (CTF) and envelope function. A computational algorithm based on constrained non-linear optimization is developed to estimate the essential parameters in the CTF and envelope function model simultaneously and automatically. The application of this estimation method is demonstrated with focal series images of amorphous carbon film as well as images of ice-embedded icosahedral virus particles suspended across holes. PMID:19250460
The phase-integral method for radiative transfer problems with highly-peaked phase functions
NASA Technical Reports Server (NTRS)
Fricke, C. L.
1978-01-01
Complete solutions to the radiative transfer equation, including both azimuth and depth dependence, are provided by the discrete-ordinate method of Chandrasekhar, but these solutions are often limited because of large computer requirements. This paper presents a 'phase-integral' method which greatly reduces the number of discrete ordinates needed in the solution for highly peaked phase functions. A composite quadrature method is shown to be effective in further reducing the number of discrete ordinates required for highly anisotropic phase functions. Examples are given to indicate convergence requirements and expected accuracy in the complete solution for Henyey-Greenstein and cloud-type phase functions.
Yang, Chao; Jiang, Wen; Chen, Dong-Hua; Adiga, Umesh; Ng, Esmond G.; Chiu, Wah
2008-07-28
The three-dimensional reconstruction of macromolecules from two-dimensional single-particle electron images requires determination and correction of the contrast transfer function (CTF) and envelope function. A computational algorithm based on constrained non-linear optimization is developed to estimate the essential parameters in the CTF and envelope function model simultaneously and automatically. The application of this estimation method is demonstrated with focal series images of amorphous carbon film as well as images of ice-embedded icosahedral virus particles suspended across holes.
Finkina, E. I.; Melnikova, D. N.; Bogdanov, I. V.; Ovchinnikova, T. V.
2016-01-01
Among a variety of molecular factors of the plant innate immune system, small proteins that transfer lipids and exhibit a broad spectrum of biological activities are of particular interest. These are lipid transfer proteins (LTPs). LTPs are interesting to researchers for three main features. The first feature is the ability of plant LTPs to bind and transfer lipids, whereby these proteins got their name and were combined into one class. The second feature is that LTPs are defense proteins that are components of plant innate immunity. The third feature is that LTPs constitute one of the most clinically important classes of plant allergens. In this review, we summarize the available data on the plant LTP structure, biological properties, diversity of functions, mechanisms of action, and practical applications, emphasizing their role in plant physiology and their significance in human life. PMID:27437139
NASA Astrophysics Data System (ADS)
Zhang, Hao; Voss, Kenneth J.
2005-02-01
To understand the connection between single-particle optics and the optics of a closely packed surface, controlled laboratory measurements of bidirectional reflectance distribution functions on layers of polymer and glass spheres are carried out. The measurements are compared with predictions from five radiative-transfer models; the Hapke's models, the Lumme-Bowell model, the BRF algorithm of Mishchenko et al., and the discrete ordinate radiative transfer. It is found that models of strict numerical radiative-transfer equations (RTEs) predict measurements well in some regions but have errors in both forward-and backward-scattering directions. The improved Hapke's model, although it has an anisotropic multiple-scattering term, still produces considerable errors compared with the strict RTE. The difference can be attributed to the exclusion of a diffraction contribution in the Hapke model.
NASA Astrophysics Data System (ADS)
Bandyopadhyay, Arkamita; Pati, Swapan K.
2015-03-01
Density functional theory calculations have been performed on three charge transfer donor-acceptor (D-A) molecular pairs, i.e. naphthalene-diamine (Naph) and tetrathiafulvalene (TTF) molecules as electron donors and benzene-diimide (Diimide) and tetracyanoquinodimethane (TCNQ) as electron acceptors. Structural, charge transfer and optical properties of the systems have been studied. The D-A pairs then has been considered inside a macrocycle (cucurbit[8]uril) cavity and Naph-Diimide and TTF-Diimide pairs have been shown to exhibit changes in their structures and orientations, TTF-TCNQ pair does not show any significant structural change. Our work suggests that these changes in structures or orientations are result of electronic repulsion between the keto group oxygen atoms and it can lead to tuning of charge transfer and optical properties of the systems.
Pauen, Sabina; Bechtel-Kuehne, Sabrina
2016-07-01
This report investigates tool learning and its relations to executive functions (EFs) in toddlers. In Study 1 (N = 93), 18-, 20-, 22-, and 24-month-old children learned equally well to choose a correct tool from observation, whereas performance based on feedback improved with age. Knowledge transfer showed significant progress after 22 months of age: Older children ignored irrelevant features more easily and adjusted their behavior more flexibly. Study 2 (N = 62) revealed that spontaneous transfer in 22- to 24-month-olds was related to set-shifting skills and response inhibition. Flexible adaptation to feedback correlated with working-memory capacity. These findings suggest that toddlerhood is a highly dynamic phase of tool learning and that EFs are related to transfer performance at this age. PMID:27138651
New Precision Measurements of Deuteron Structure Function A(Q) at Low Momentum Transfer
Lee, Byungwuek
2009-08-01
Differences between previous measurements of low momentum transfer electron-deuteron elastic scattering prevent a clean determination of even the sign of the leading low momentum transfer relativistic corrections, or of the convergence of chiral perturbation theory. We have attempted to resolve this issue with a new high-precision measurement in Jefferson Lab Hall A. Elastic electron scattering was measured on targets of tantalum, carbon, hydrogen, and deuterium at beam energy of 685 MeV. The four-momentum transfer covered the range of 0.15 - 0.7 GeV. The experiment included a new beam calorimeter, to better calibrate the low beam currents used in the experiment, and new collimators to better define the spectrometer solid angles. We obtained cross sections of deuteron as ratios to hydrogen cross sections. A fit function of B(Q) world data is newly made and subtracted from cross sections to find values of A(Q).
NASA Astrophysics Data System (ADS)
Wiktor, Julia; Jomard, Gérald; Torrent, Marc
2015-09-01
Many techniques have been developed in the past in order to compute positron lifetimes in materials from first principles. However, there is still a lack of a fast and accurate self-consistent scheme that could handle accurately the forces acting on the ions induced by the presence of the positron. We will show in this paper that we have reached this goal by developing the two-component density functional theory within the projector augmented-wave (PAW) method in the open-source code abinit. This tool offers the accuracy of the all-electron methods with the computational efficiency of the plane-wave ones. We can thus deal with supercells that contain few hundreds to thousands of atoms to study point defects as well as more extended defects clusters. Moreover, using the PAW basis set allows us to use techniques able to, for instance, treat strongly correlated systems or spin-orbit coupling, which are necessary to study heavy elements, such as the actinides or their compounds.
Li, Liqi; Cui, Xiang; Yu, Sanjiu; Zhang, Yuan; Luo, Zhong; Yang, Hua; Zhou, Yue; Zheng, Xiaoqi
2014-01-01
Protein structure prediction is critical to functional annotation of the massively accumulated biological sequences, which prompts an imperative need for the development of high-throughput technologies. As a first and key step in protein structure prediction, protein structural class prediction becomes an increasingly challenging task. Amongst most homological-based approaches, the accuracies of protein structural class prediction are sufficiently high for high similarity datasets, but still far from being satisfactory for low similarity datasets, i.e., below 40% in pairwise sequence similarity. Therefore, we present a novel method for accurate and reliable protein structural class prediction for both high and low similarity datasets. This method is based on Support Vector Machine (SVM) in conjunction with integrated features from position-specific score matrix (PSSM), PROFEAT and Gene Ontology (GO). A feature selection approach, SVM-RFE, is also used to rank the integrated feature vectors through recursively removing the feature with the lowest ranking score. The definitive top features selected by SVM-RFE are input into the SVM engines to predict the structural class of a query protein. To validate our method, jackknife tests were applied to seven widely used benchmark datasets, reaching overall accuracies between 84.61% and 99.79%, which are significantly higher than those achieved by state-of-the-art tools. These results suggest that our method could serve as an accurate and cost-effective alternative to existing methods in protein structural classification, especially for low similarity datasets. PMID:24675610
NASA Astrophysics Data System (ADS)
Xiang, Shang; Jiang, Weikang; Pan, Siwei
2015-12-01
A modified inverse patch transfer function (iPTF) method is used to reconstruct the normal velocities of the target source in a noisy environment. The iPTF method simplifies the Helmholtz integral equation to one term by constructing a Green's function satisfying Neumann boundary conditions for an enclosure, which is generally constructed by slowly convergent modal expansions. The main objective of the present work is to provide an evanescent Green's function to improve the convergence of calculations. A brief description of the iPTF method and two sets of Green's functions for a rectangular cavity are presented firstly. In simulations, both the Green's functions are used to calculate the condition numbers of impedance matrices describing the relation between source and measurement patches, and the time cost of calculation based on the two sets of Green's functions at 450 Hz is compared. Double pressure measurements are then employed as the input data instead of pressure and velocity measurements. The normal velocities of two baffled loudspeakers are reconstructed by the combination of a measurement method and a Green's function in the presence of a disturbing source in the frequency range of 50-1000 Hz. In addition, the double pressure measurements are examined by an experiment. The precise identification of the sources indicates that the double pressure measurements are capable of localizing sources in a noisy environment. It is also found that the reconstruction with the evanescent Green's functions is slightly better than that with the modal expansions.
NASA Astrophysics Data System (ADS)
Teale, Andrew M.; Lutnæs, Ola B.; Helgaker, Trygve; Tozer, David J.; Gauss, Jürgen
2013-01-01
Accurate sets of benchmark nuclear-magnetic-resonance shielding constants and spin-rotation constants are calculated using coupled-cluster singles-doubles (CCSD) theory and coupled-cluster singles-doubles-perturbative-triples [CCSD(T)] theory, in a variety of basis sets consisting of (rotational) London atomic orbitals. The accuracy of the calculated coupled-cluster constants is established by a careful comparison with experimental data, taking into account zero-point vibrational corrections. Coupled-cluster basis-set convergence is analyzed and extrapolation techniques are employed to estimate basis-set-limit quantities, thereby establishing an accurate benchmark data set. Together with the set provided for rotational g-tensors and magnetizabilities in our previous work [O. B. Lutnæs, A. M. Teale, T. Helgaker, D. J. Tozer, K. Ruud, and J. Gauss, J. Chem. Phys. 131, 144104 (2009)], 10.1063/1.3242081, it provides a substantial source of consistently calculated high-accuracy data on second-order magnetic response properties. The utility of this benchmark data set is demonstrated by examining a wide variety of Kohn-Sham exchange-correlation functionals for the calculation of these properties. None of the existing approximate functionals provide an accuracy competitive with that provided by CCSD or CCSD(T) theory. The need for a careful consideration of vibrational effects is clearly illustrated. Finally, the pure coupled-cluster results are compared with the results of Kohn-Sham calculations constrained to give the same electronic density. Routes to future improvements are discussed in light of this comparison.
NASA Astrophysics Data System (ADS)
Shi, De-Heng; Liu, Yu-Fang; Sun, Jin-Feng; Zhu, Zun-Lue; Yang, Xiang-Dong
2006-12-01
The reasonable dissociation limit of the second excited singlet state B1Π of 7LiH molecule is obtained. The accurate dissociation energy and equilibrium geometry of the B1Π state are calculated using a symmetry-adapted-cluster configuration-interaction method in full active space. The whole potential energy curve for the B1Π state is obtained over the internuclear distance ranging from about 0.10 nm to 0.54 nm, and has a least-square fit to the analytic Murrell-Sorbie function form. The vertical excitation energy is calculated from the ground state to the B1Π state and compared with previous theoretical results. The equilibrium internuclear distance obtained by geometry optimization is found to be quite different from that obtained by single-point energy scanning under the same calculation condition. Based on the analytic potential energy function, the harmonic frequency value of the B1Π state is estimated. A comparison of the theoretical calculations of dissociation energies, equilibrium interatomic distances and the analytic potential energy function with those obtained by previous theoretical results clearly shows that the present work is more comprehensive and in better agreement with experiments than previous theories, thus it is an improvement on previous theories.
Doherty, Kimberly R. Talbert, Dominique R.; Trusk, Patricia B.; Moran, Diarmuid M.; Shell, Scott A.; Bacus, Sarah
2015-05-15
Safety pharmacology studies that evaluate new drug entities for potential cardiac liability remain a critical component of drug development. Current studies have shown that in vitro tests utilizing human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) may be beneficial for preclinical risk evaluation. We recently demonstrated that an in vitro multi-parameter test panel assessing overall cardiac health and function could accurately reflect the associated clinical cardiotoxicity of 4 FDA-approved targeted oncology agents using hiPS-CM. The present studies expand upon this initial observation to assess whether this in vitro screen could detect cardiotoxicity across multiple drug classes with known clinical cardiac risks. Thus, 24 drugs were examined for their effect on both structural (viability, reactive oxygen species generation, lipid formation, troponin secretion) and functional (beating activity) endpoints in hiPS-CM. Using this screen, the cardiac-safe drugs showed no effects on any of the tests in our panel. However, 16 of 18 compounds with known clinical cardiac risk showed drug-induced changes in hiPS-CM by at least one method. Moreover, when taking into account the Cmax values, these 16 compounds could be further classified depending on whether the effects were structural, functional, or both. Overall, the most sensitive test assessed cardiac beating using the xCELLigence platform (88.9%) while the structural endpoints provided additional insight into the mechanism of cardiotoxicity for several drugs. These studies show that a multi-parameter approach examining both cardiac cell health and function in hiPS-CM provides a comprehensive and robust assessment that can aid in the determination of potential cardiac liability. - Highlights: • 24 drugs were tested for cardiac liability using an in vitro multi-parameter screen. • Changes in beating activity were the most sensitive in predicting cardiac risk. • Structural effects add in
NASA Technical Reports Server (NTRS)
Weissman, D. E.; Johnson, J. W.
1984-01-01
The directional spectrum and the microwave modulation transfer function of ocean waves can be measured with the airborne two frequency scatterometer technique. Similar to tower based observations, the aircraft measurements of the Modulation Transfer Function (MTF) show that it is strongly affected by both wind speed and sea state. Also detected are small differences in the magnitudes of the MTF between downwind and upwind radar look directions, and variations with ocean wavenumber. The MTF inferred from the two frequency radar is larger than that measured using single frequency, wave orbital velocity techniques such as tower based radars or ROWS measurements from low altitude aircraft. Possible reasons for this are discussed. The ability to measure the ocean directional spectrum with the two frequency scatterometer, with supporting MTF data, is demonstrated.
NASA Technical Reports Server (NTRS)
Weissman, D. E.; Johnson, J. W.
1986-01-01
The directional spectrum and the microwave modulation transfer function of ocean waves can be measured with the airborne two frequency scatterometer technique. Similar to tower based observations, the aircraft measurements of the Modulation Transfer Function (MTF) show that it is strongly affected by both wind speed and sea state. Also detected are small differences in the magnitudes of the MTF between downwind and upwind radar look directions, and variations with ocean wavenumber. The MTF inferred from the two frequency radar is larger than that measured using single frequency, wave orbital velocity techniques such as tower based radars or ROWS measurements from low altitude aircraft. Possible reasons for this are discussed. The ability to measure the ocean directional spectrum with the two frequency scatterometer, with supporting MTF data, is demonstrated.
Sensor modulation transfer function measurement using band-limited laser speckle.
Chen, Xi; George, Nicholas; Agranov, Gennadiy; Liu, Changmeng; Gravelle, Bob
2008-11-24
A new methodology for image sensor modulation transfer function measurement using band-limited laser speckle is presented. We use a circular opal milk glass diffuser illuminated by a 5 mW He-Ne laser and a linear polarizer to generate band-limited speckle on the sensor. The power spectral density cut-off frequency of the speckle is chosen to be twice that of the sensor Nyquist frequency by placing the sensor at the specific Z location along the optical axis. For the speckle input, we calculate the power spectral density at the sensor using the Rayleigh-Sommerfeld integral and then measure the output power spectral density for the speckle pattern captured by the sensor. With these data, the two-dimensional image sensor modulation transfer function (MTF) is calculated. PMID:19030090
Recent advances in the modulation transfer function testing of detector arrays
NASA Astrophysics Data System (ADS)
Ducharme, Alfred D.
2008-08-01
The increased complexity of imaging sensors and total number of discrete detector sites has challenged traditional testing methods. The importance of reliable modulation transfer function testing of imaging sensors with high uncertainty has consequently grown more difficult. In this paper we demonstrate the design of an aperture for the generation of laser speckle with a flat power spectrum covering a wide-band of the measurement spatial frequency range. This aperture allows for the measurement of modulation transfer function (MTF) from zero to twice the Nyquist frequency of a twodimensional detector array. This design mitigates many of the measurement issues inherent in other aperture designs. The MTF measurement of a charge-coupled device (CCD) detector array is used to demonstrate the measurement technique and illustrate the advantages of the new aperture design.
Modulation transfer function analysis for a digitally spectrum-controllable light source
NASA Astrophysics Data System (ADS)
Ma, Suodong; Wang, Yan; Pan, Qiao; Shen, Weimin
2015-08-01
Owing to the ability of generating designated spectrums as special requirements, spectrum-controllable light source has attracted huge interesting in several fields, e.g. medical science, industrial detection, defense-related testing. In principle, optical performance of a spectrum-controllable light source can be predicted by some transfer functions of the corresponding system, e.g. modulation transfer function (MTF). Unfortunately, the aforementioned research work is still lacking at present although it is meaningful for the optical design and evaluation of this new kind of light sources. Hence, a MTF model for a modified version of our previously-proposed spectrum-controllable light source system based on a Digital Micromirror Device (DMD) and an Offner dispersion configuration with a convex grating is deduced as an example. Related preliminary analyses have been present in this paper as well.
NASA Technical Reports Server (NTRS)
Taylor, Lawrence W., Jr.; Day, Richard E.
1961-01-01
A simulator study and flight tests were performed to determine the levels of static stability and damping necessary to enable a pilot to control the longitudinal and lateral-directional dynamics of a vehicle for short periods of time. Although a basic set of aerodynamic characteristics was used, the study was conducted so that the results would be applicable to a wide range of flight conditions and configurations. Novel piloting techniques were found which enabled the pilot to control the vehicle at conditions that were otherwise uncontrollable. The influence of several critical factors in altering the controllability limits was also investigated. Several human transfer functions were used which gave fairly good representations of the controllability limits determined experimentally for the short-period longitudinal, directional, and lateral modes. A transfer function with approximately the same gain and phase angle as the pilot at the controlling frequencies along the controllability limits was also derived.
Determination of poles and zeros of transfer functions for flexible spacecraft attitude control
NASA Technical Reports Server (NTRS)
Ohkami, Y.; Likins, P. W.
1976-01-01
The transfer function matrix is obtained for a three-input and three-output model of minimum sensors and actuators for the attitude control system of flexible spacecraft, and a method is described for determining the poles and zeros of this transfer function. Three cases are considered: (1) the actuators and the sensors are all attached to the primary body, (2) the actuators are on the primary body and the sensors are on the sub-body, and (3) the actuators are on the sub-body and the sensors are on the primary body. The zero-determination problem is shown to reduce to eigenvalue calculations of a matrix which is constructed from the inertial and modal matrices in a simple fashion.
Clark, Edward L.; Henfling, John F.; McBride, Donald D.
1999-05-12
An inverse Fourier transform method for removing lag from pressure measurements has been used by various researchers, given an experimentally derived transfer function to characterize the pressure plumbing. This paper presents a Method of Characteristics (MOC) solution technique for predicting the transfer function and thus easily determining its sensitivity to various plumbing pammeters. The MOC solution has been used in the pipeline industry for some time for application to transient flow in pipelines, but it also lends itself well to this application. For highly nonsteady pressures frequency-dependent friction can cause significant distortion of the traveling waves. This is accounted for in the formulation. A simple bench experiment and proof-of-principle test provide evidence to establish the range of validity of the method.
Modulation transfer function measuring of charge-coupled devices using laser speckle
NASA Astrophysics Data System (ADS)
Liu, Minghua; Zhen, Wenlong; Liang, Yinzhong; Yu, Mozhi; He, Ping'an; Cheng, Changjun
1996-10-01
Based on the statistical properties of laser speckle, the response for laser speckle passing through a linear shift- invariant system is studied. This paper presents a method for testing the modulation transfer function (MTF) of charge-coupled devices below the Nyquist frequency. A new scattering microcrystalline glass material generates laser speckle. The instrument is designed and test results show that this technique is a variable MTF measurement approach. The difference of the results of each test is within 0.03.
Method For Measuring Modulation Transfer Function Of CCD's Using Laser Speckle
NASA Astrophysics Data System (ADS)
Boreman, G.; Dereniak, E. L.
1984-11-01
A new method has been developed to measure the modulation transfer function (MTF) of an array out to the Nyquist frequency without high-quality optical or mechanical components, without precision alignment, and with only one moving part. Test results for an infrared staring array of PtSi Schottky barrier construction show that this technique is a viable MTF measurement approach in the 3 to 5 pm spectral regions.
Method for measuring modulation transfer function of charge-coupled devices using laser speckle
NASA Astrophysics Data System (ADS)
Boreman, G.; Dereniak, E. L.
1986-01-01
A new method has been developed to measure the modulation transfer function (MTF) of an array out to the Nyquist frequency without high quality optical or mechanical components, without precision alignment, and with only one moving part. Test results for an infrared staring array of PtSi Schottky barrier construction show that this technique is a viable MTF measurement approach in the 3 to 5 micron spectral region.
Modulation Transfer Function Measurement of Infrared Focal-Plane Arrays with Small Fill Factors
NASA Astrophysics Data System (ADS)
de la Barrière, Florence; Druart, Guillaume; Guérineau, Nicolas; Rommeluère, Sylvain; Mugnier, Laurent; Gravrand, Olivier; Baier, Nicolas; Lhermet, Nicolas; Destefanis, Gérard; Derelle, Sophie
2012-10-01
This paper describes an original method to measure the modulation transfer function (MTF) of an infrared focal-plane array (IRFPA), based on a diffraction grating called a continuously self-imaging grating (CSIG). We give a general methodology to design the test bench, and we describe the data processing approach which has been developed to extract relevant information about the size of the photodiodes and filtering effects. The MTF measurement capability of this method is illustrated with a cooled IRFPA.
Measurement of modulation transfer function for four types of imaging elements used in fast cameras
Estrella, R.M.; Sammons, T.J. . Amador Valley Operations); Thomas, S.W. )
1991-01-01
We have measured the modulation transfer function (MTF) of fiber- optic bundles (reducers), minifiers (inverting, electrostatically focused imaging tube reducers), microchannel plate image intensifiers (MCPIs), and streak tubes as part of our ongoing device evaluation program aimed at precise characterization of various imaging elements used in fast cameras. This paper describes our measurement equipment and techniques and shows plots of MTF measurements for each of four types of fast-camera elements tested. 6 refs., 9 figs.
Modulation transfer function of a lens measured with a random target method.
Levy, E; Peles, D; Opher-Lipson, M; Lipson, S G
1999-02-01
We measured the modulation transfer function (MTF) of a lens in the visible region using a random test target generated on a computer screen. This is a simple method to determine the entire MTF curve in one measurement. The lens was obscured by several masks so that the measurements could be compared with the theoretically calculated MTF. Excellent agreement was obtained. Measurement noise was reduced by use of a large number of targets generated on the screen. PMID:18305663
NASA Astrophysics Data System (ADS)
Swindles, Graeme T.; Holden, Joseph; Raby, Cassandra L.; Turner, T. Edward; Blundell, Antony; Charman, Dan J.; Menberu, Meseret Walle; Kløve, Bjørn
2015-07-01
Transfer functions are now commonly used to reconstruct past environmental variability from palaeoecological data. However, such approaches need to be critically appraised. Testate amoeba-based transfer functions are an established method for the quantitative reconstruction of past water-table variations in peatlands, and have been applied to research questions in palaeoclimatology, peatland ecohydrology and archaeology. We analysed automatically-logged peatland water-table data from dipwells located in England, Wales and Finland and a suite of three year, one year and summer water-table statistics were calculated from each location. Surface moss samples were extracted from beside each dipwell and the testate amoebae community composition was determined. Two published transfer functions were applied to the testate-amoeba data for prediction of water-table depth (England and Europe). Our results show that estimated water-table depths based on the testate amoeba community reflect directional changes, but that they are poor representations of the real mean or median water-table magnitudes for the study sites. We suggest that although testate amoeba-based reconstructions can be used to identify past shifts in peat hydrology, they cannot currently be used to establish precise hydrological baselines such as those needed to inform management and restoration of peatlands. One approach to avoid confusion with contemporary water-table determinations is to use residuals or standardised values for peatland water-table reconstructions. We contend that our test of transfer functions against independent instrumental data sets may be more powerful than relying on statistical testing alone.
NASA Astrophysics Data System (ADS)
Thanh Bui, Dang; Thanh Nguyen, Chi; Ledoux-Rak, Isabelle; Zyss, Joseph; Journet, Bernard
2011-12-01
This paper presents an instrumentation system developed to improve the operation of an electro-optic modulator (EOM). During their operating time, EOM are subject to a drift of the optical transfer function; therefore the initial tuning of the bias point no longer corresponds to the best characteristics of the device. Because of this drift the EOM no longer behaves linearly and there is degradation during time of the performances of the system in which the EOM is included. To determine the drift, a low frequency modulation signal (at 500 Hz) is applied to the EOM and the second harmonic component at 1 kHz is detected. A new criterion is introduced for estimating the nonlinearity and for compensating the drift of the transfer function, keeping the optical bias point at the quadrature position. Temperature changes significantly influence the EOM characteristics. Thus, the instrumentation system has to be simultaneously developed with temperature control and drift compensation of the optical transfer function. The design is based on PSOC microcontrollers for tuning the different parameters, for data acquisition and regulation process. By setting the temperature to some specific values, it is possible to test the behaviour of the modulator. Finally, by using both temperature and bias point control, a significant reduction of the nonlinearity can be obtained during 2 h of experiment: the biasing point at the quadrature point of the transfer function which corresponds to the most linear behaviour can be stabilized within ±0.22% of the half-wave voltage. All the works presented here were carried out with a Mach-Zehnder intensity modulator made of lithium niobate, but it is also possible to apply this method to other kinds of material, for example polymer material.
A simple parameterization for quality factor as a function of linear energy transfer
NASA Technical Reports Server (NTRS)
Townsend, Lawrence W.; Wilson, John; Cucinotta, Francis A.
1987-01-01
The paper presents a simple analytic approximation of the radiation quality factor (Q) as a function of linear energy transfer for use in radiation protection calculations. The paper also presents estimated quality factors in water for protons over a broad range of incident energies. It is shown that the quality factors are less than unity for all proton energies greater than 13 MeV.
Method of calculating retroreflector-array transfer functions. [laser range finders
NASA Technical Reports Server (NTRS)
Arnold, D. A.
1978-01-01
Techniques and equations used in calculating the transfer functions to relate the observed return laser pulses to the center of mass of the Lageos satellite retroflector array, and for most of the retroreflector-equipped satellites now in orbit are described. The methods derived include the effects of coherent interference, diffraction, polarization, and dihedral-angle offsets. Particular emphasis is given to deriving expressions for the diffraction pattern and active reflecting area of various cube-corner designs.
NASA Astrophysics Data System (ADS)
Shao, Xiaopeng; Yang, Hong; Zhang, Shaohui; Jin, Zhenhua; Du, Juan
2013-09-01
Satellite imagery always has low-resolution causing poor application in practice because the serious degradation in imaging is resulted in many factors such as atmospheric turbulence, cloud, and aberration of optical system. To reconstruct the degraded remote sensing images with a high quality, we designed an algorithm to estimate the system modulation transfer function (MTF) accurately. Phase congruency is employed to detect the edges and corners of the image first, then the significant edges, which are utilized to estimate the edge spread function (ESF) using inclined edge method, are picked up from above features through a certain line detection measurement. An image restoration algorithm based on total variation (TV) is introduced to deconvolute the degraded image with the estimated MTF which is derived from the ESF. The experiments show that this method is adaptive and efficient to recover the remote sensing images taken from a Chinese Satellite. The restored images with a higher resolution and higher signal-to-noise ratio (SNR) will improve the applications greatly.
Stability Analysis of Absorption Chiller-Heaters by Applying Transfer Function
NASA Astrophysics Data System (ADS)
Fujii, Tatsuo; Miyake, Satoshi; Oka, Masahiro; Mori, Kiyoyuki
A transfer function approach is found to be a practical method for ensuring stable operation of absorption chiller-heaters. The transfer function model is based on a solution-circuit of the machine, which dominates the stability of the operation. This model includes a solution pump, a generator with an overflow weir, and a float valve. We found that the solution-circuit system is designed with the cascade control, which makes the system stable. In this construction, the float valve actuates a primary control loop, and the overflow weir actuates a secondary loop. The effects of the characteristic of the solution pump and the overflow weir are estimated by the degree of the stabilities, which are the gain margin and the phase margin. We found that the characteristic of the solution pump strongly effects the stability by enhancing the effect of the cascade control and improving the stability. So it is essential for a better stability analysis model. According to these results, the established model is useful for quantitatively predicting the stabilities of a chiller-heater in operation, and simultaneously reducing its size and improving the stability of operation. We conclude that the methodology based on transfer function can provide compact and reliable absorption chiller-heaters.
Detecting damage in non-uniform beams using the dereverberated transfer function response
NASA Astrophysics Data System (ADS)
Purekar, A. S.; Pines, D. J.; Purekar, A. S.
2000-08-01
Delamination damage in composite rotorcraft flexbeams caused by excessive vibratory and fatigue loads can lead to degradation in flapwise and lagwise performance of the rotor blade. In addition, delaminations can result in rapid fatigue failure of these tailored composite elements leading to catastrophic results. A novel damage detection strategy is evaluated in this work which attempts to exploit the dereverberated transfer function response of beams with tapered geometries. This approach avoids high fidelity finite element models of damaged one-dimensional beams with non-uniform geometries. To obtain the dereverberated transfer function response, a virtual control force is applied to the reverberated transfer function response to remove resonant and anti-resonant dynamics associated with the beam's boundary conditions. Magnitude and phase characteristics between each actuator and sensor can then be used to infer changing structural properties. Analytical and experimental results suggest that this approach can be used to quantitatively and qualitatively infer delamination damage in non-uniform beams. Experimental results are displayed for beams with varying thickness and width tapers.
Single-input/single-output transfer functions for a flexible slewing link
NASA Technical Reports Server (NTRS)
Barbieri, Enrique
1993-01-01
Truncated linear models based on constrained and unconstrained mode expansions for a flexible link with torque actuation at its hub led us to examine the behavior of the open-loop-zeros of five commonly used SISO transfer functions. We arrive at new conclusions with regard to minimum- and non-minimum-phase zeros, and passivity of the transfer functions. The flexible-to-rigid inertia (FRI) ratio plays an important role in the determination of these characteristics. This paper illustrates how the zero locations of some of the transfer functions are dramatically affected by the FRI ratio. We also investigate the performance of a hub angle, hub rate, and relative tip position static feedback controller based on a reduced-order constrained mode model when applied to both unconstrained and constrained mode models of the same dimension. Simulations indicate that the constrained model can be stable while the unconstrained model is not for high FRI ratios. Our findings can provide useful information to designers in cases where the controller is sensitive to the 1ocation of the plant's zeros.
Keissar, K; Maestri, R; Pinna, G D; La Rovere, M T; Gilad, O
2010-07-01
A novel approach for the estimation of baroreflex sensitivity (BRS) is introduced based on time-frequency analysis of the transfer function (TF). The TF method (TF-BRS) is a well-established non-invasive technique which assumes stationarity. This condition is difficult to meet, especially in cardiac patients. In this study, the classical TF was replaced with a wavelet transfer function (WTF) and the classical coherence was replaced with wavelet transform coherence (WTC), adding the time domain as an additional degree of freedom with dynamic error estimation. Error analysis and comparison between WTF-BRS and TF-BRS were performed using simulated signals with known transfer function and added noise. Similar comparisons were performed for ECG and blood pressure signals, in the supine position, of 19 normal subjects, 44 patients with a history of previous myocardial infarction (MI) and 45 patients with chronic heart failure. This yielded an excellent linear association (R > 0.94, p < 0.001) for time-averaged WTF-BRS, validating the new method as consistent with a known method. The additional advantage of dynamic analysis of coherence and TF estimates was illustrated in two physiological examples of supine rest and change of posture showing the evolution of BRS synchronized with its error estimations and sympathovagal balance. PMID:20585147
Contrast transfer function in grating-based x-ray phase-contrast imaging
NASA Astrophysics Data System (ADS)
Huang, Jianheng; Du, Yang; Lin, Danying; Liu, Xin; Niu, Hanben
2014-05-01
x-Ray grating interferometry is a method for x-ray wave front sensing and phase-contrast imaging that has been developed over past few years. Contrast and resolution are the criteria used to specify the quality of an image. In characterizing the performance of this interferometer, the contrast transfer function is considered in this paper. The oscillatory nature of the contrast transfer function (CTF) is derived and quantified for this interferometer. The illumination source and digital detector are both considered as significant factors controlling image quality, and it can be noted that contrast and resolution in turn depends primarily on the projected intensity profile of the array source and the pixel size of the detector. Furthermore, a test pattern phantom with a well-controlled range of spatial frequencies was designed and imaging of this phantom was simulated by a computer. Contrast transfer function behavior observed in the simulated image is consistent with our theoretical CTF. This might be beneficial for the evaluation and optimization of a grating-based x-ray phase contrast imaging system.
NASA Astrophysics Data System (ADS)
Telford, R. J.; Birks, H. J. B.
2005-11-01
The estimation of the predictive power of transfer functions assumes that the test sites are independent of the modelling sites. Cross-validation in the presence of spatial autocorrelation seriously violates this assumption. This assumption and the consequences of its violation have not been discussed before. We show, by simulation, that the expected r2 of a transfer function model from an autocorrelated environment can be high, and is not near zero as commonly assumed. We investigate a foraminiferal sea surface temperature training set for the North Atlantic, for which, with cross-validation, the modern analogue technique (MAT) and artificial neural networks (ANN) outperform transfer function methods based on a unimodal species-environment response model. However, when a spatially independent test set, the South Atlantic, is used, all models have a similar predictive power. We show that there is a spatial structure in the foraminiferal assemblages even after accounting for temperature, presumably due to autocorrelations in other environmental variables. Since the residuals from MAT show little spatial structure, in contrast to the residuals of unimodal response models, we contend that MAT has inappropriately internalized the non-temperature spatial structure to improve its performance. We argue that most, if not all, estimates of the predictive power of MAT and ANN models for sea surface temperatures hitherto published are over-optimistic and misleading.
Gugliuzza, Annarosa; Pingitore, Valentino; Miriello, Domenico; Drioli, Enrico
2015-05-21
Functional single walled carbon nanotubes (SWCNTs) are assembled onto porous supports by using layer-by-layer (LBL) approaches. Directed nano-assembly of nanotubes is identified as a crucial factor for controlling the combined functions of hybrid-composite membranes, including charge and moisture transport. In both the cases, donor-acceptor interactions are indicated to be responsible for the rearrangement of nanotubes inside the LBL multilayer and their related properties. Aggregation and stratification of the carbon nanotubes along with the availability of selective-site interactions are complementarily investigated by using SEM, Raman and infrared spectroscopy, while high electrical charge and water vapor transfer are achievable, provided that a large number of connections and competitive interactions are allowed. Ohmic behavior is observed for all types of carbon nanotubes, even if better-quality charge transfer pathways are obtained with carboxylated conductive filaments. Likewise, assisted moisture regulation is succeeded when using functional filaments with the capability to establish competitive H-donor-acceptor interactions with water. PMID:25909584
NASA Technical Reports Server (NTRS)
Ko, William L.; Fleischer, Van Tran
2013-01-01
Large deformation displacement transfer functions were formulated for deformed shape predictions of highly flexible slender structures like aircraft wings. In the formulation, the embedded beam (depth wise cross section of structure along the surface strain sensing line) was first evenly discretized into multiple small domains, with surface strain sensing stations located at the domain junctures. Thus, the surface strain (bending strains) variation within each domain could be expressed with linear of nonlinear function. Such piecewise approach enabled piecewise integrations of the embedded beam curvature equations [classical (Eulerian), physical (Lagrangian), and shifted curvature equations] to yield closed form slope and deflection equations in recursive forms.
Using contrast transfer function to evaluate the effect of motion blur on microscope image quality
NASA Astrophysics Data System (ADS)
Wood, Marc C.; Wang, Xingwei; Zheng, Bin; Li, Shibo; Chen, Wei; Liu, Hong
2008-02-01
Scanning of microscope slides is an important part of cytogenetic diagnosis. Metaphase chromosomes arranged in a karyotype reveal the nature and severity of cancer and other diseases. Searching for metaphases spreads is a lengthy and tedious process that can benefit from computer aided systems. When slides are searched by such systems in continuous motion, the image quality is reduced. The motion blur is a function of the scan speed, the camera frame rate and sample time, and the level of magnification. In this study, normalized contrast transfer function (CTF) is used to define the amount of image degradation.
Parameterization of the three-dimensional room transfer function in horizontal plane.
Bu, Bing; Abhayapala, Thushara D; Bao, Chang-chun; Zhang, Wen
2015-09-01
This letter proposes an efficient parameterization of the three-dimensional room transfer function (RTF) which is robust for the position variations of source and receiver in respective horizontal planes. Based on azimuth harmonic analysis, the proposed method exploits the underlying properties of the associated Legendre functions to remove a portion of the spherical harmonic coefficients of RTF which have no contribution in the horizontal plane. This reduction leads to a flexible measuring-point structure consisting of practical concentric circular arrays to extract horizontal plane RTF coefficients. The accuracy of the above parameterization is verified through numerical simulations. PMID:26428827
Apodization and image contrast. [performance prediction in terms of modulation transfer function
NASA Technical Reports Server (NTRS)
Tschunko, H. F. A.
1979-01-01
Apodization is often defined in a restricted sense as the suppression of the outer parts (i.e., the concentric rings) of wave optical point images, which results in a higher relative concentration of energy in the central image area. In a wider sense, apodization is defined as any modification of the transmission distribution across the aperture. Generally the modulation transfer function (MTF) is not used in the treatment of apodization. To see how the imaging performance is modified, the MTF is introduced into the discussion. Besides the constant transmission, two transmission distributions which are functions of the aperture radius are considered.
Modified slanted-edge method and multidirectional modulation transfer function estimation.
Masaoka, Kenichiro; Yamashita, Takayuki; Nishida, Yukihiro; Sugawara, Masayuki
2014-03-10
The slanted-edge method specified in ISO Standard 12233, which measures the modulation transfer function (MTF) by analyzing an image of a slightly slanted knife-edge target, is not robust against noise because it takes the derivative of each data line in the edge-angle estimation. We propose here a modified method that estimates the edge angle by fitting a two-dimensional function to the image data. The method has a higher accuracy, precision, and robustness against noise than the ISO 12233 method and is applicable to any arbitrary pixel array, enabling a multidirectional MTF estimate in a single measurement of a starburst image. PMID:24663939
2015-01-01
Background Accurately predicting the binding affinities of large sets of protein-ligand complexes is a key challenge in computational biomolecular science, with applications in drug discovery, chemical biology, and structural biology. Since a scoring function (SF) is used to score, rank, and identify drug leads, the fidelity with which it predicts the affinity of a ligand candidate for a protein's binding site has a significant bearing on the accuracy of virtual screening. Despite intense efforts in developing conventional SFs, which are either force-field based, knowledge-based, or empirical, their limited predictive power has been a major roadblock toward cost-effective drug discovery. Therefore, in this work, we present novel SFs employing a large ensemble of neural networks (NN) in conjunction with a diverse set of physicochemical and geometrical features characterizing protein-ligand complexes to predict binding affinity. Results We assess the scoring accuracies of two new ensemble NN SFs based on bagging (BgN-Score) and boosting (BsN-Score), as well as those of conventional SFs in the context of the 2007 PDBbind benchmark that encompasses a diverse set of high-quality protein families. We find that BgN-Score and BsN-Score have more than 25% better Pearson's correlation coefficient (0.804 and 0.816 vs. 0.644) between predicted and measured binding affinities compared to that achieved by a state-of-the-art conventional SF. In addition, these ensemble NN SFs are also at least 19% more accurate (0.804 and 0.816 vs. 0.675) than SFs based on a single neural network that has been traditionally used in drug discovery applications. We further find that ensemble models based on NNs surpass SFs based on the decision-tree ensemble technique Random Forests. Conclusions Ensemble neural networks SFs, BgN-Score and BsN-Score, are the most accurate in predicting binding affinity of protein-ligand complexes among the considered SFs. Moreover, their accuracies are even higher
Backlund, Mikael P.; Lew, Matthew D.; Backer, Adam S.; Sahl, Steffen J.; Grover, Ginni; Agrawal, Anurag; Piestun, Rafael; Moerner, W. E.
2014-01-01
Single-molecule-based super-resolution fluorescence microscopy has recently been developed to surpass the diffraction limit by roughly an order of magnitude. These methods depend on the ability to precisely and accurately measure the position of a single-molecule emitter, typically by fitting its emission pattern to a symmetric estimator (e.g. centroid or 2D Gaussian). However, single-molecule emission patterns are not isotropic, and depend highly on the orientation of the molecule’s transition dipole moment, as well as its z-position. Failure to account for this fact can result in localization errors on the order of tens of nm for in-focus images, and ~50–200 nm for molecules at modest defocus. The latter range becomes especially important for three-dimensional (3D) single-molecule super-resolution techniques, which typically employ depths-of-field of up to ~2 μm. To address this issue we report the simultaneous measurement of precise and accurate 3D single-molecule position and 3D dipole orientation using the Double-Helix Point Spread Function (DH-PSF) microscope. We are thus able to significantly improve dipole-induced position errors, reducing standard deviations in lateral localization from ~2x worse than photon-limited precision (48 nm vs. 25 nm) to within 5 nm of photon-limited precision. Furthermore, by averaging many estimations of orientation we are able to improve from a lateral standard deviation of 116 nm (~4x worse than the precision, 28 nm) to 34 nm (within 6 nm). PMID:24817798
NASA Astrophysics Data System (ADS)
Chakoli, Ali Nabipour; Cai, Wei; Jiehe, Sui; Feng, Jiang Tao
Multiwalled carbon nanotubes (MWCNTs) grafted with poly(L-lactide-e-caprolactone) (PCLA) were synthesized by in situ ring opening polymerization and used as a reinforcement for neat PCLA. The analyzed data revealed that the applied tensile load on the composite was transferred to the functionalized MWCNTs, leading to a strain failure of the MWCNTs rather than an adhesive failure between the MWCNTs and the matrix. In comparison between the functionalized and pristine MWCNTs, as reinforcement materials for PCLA random copolymers (80% L-lactide (LA), 20% e-caprolactone (CL)) (PCLAR80), the functionalized MWCNTs are more effective reinforcement materials than pristine MWCNTs. In comparison with the neat PCLAR80, the increasing in tensile strength (28.03%) and elongation at failure (49.6%) when functionalized MWCNT loading reaches 1.0 wt%, indicate that an effective reinforcement of the MWCNT-OH-g-PCLA.
Lam, Quan; Kato, Mallory; Cheruzel, Lionel
2016-05-01
The unique photochemical properties of Ru(II)-diimine complexes have helped initiate a series of seminal electron transfer studies in metalloenzymes. It has thus been possible to experimentally determine rate constants for long-range electron transfers. These studies have laid the foundation for the investigation of reactive intermediates in heme proteins and for the design of light-activated biocatalysts. Various metalloenzymes such as hydrogenase, carbon monoxide dehydrogenase, nitrogenase, laccase and cytochrome P450 BM3 have been functionalized with Ru(II)-diimine complexes. Upon visible light-excitation, these photosensitized metalloproteins are capable of sustaining photocatalytic activity to reduce small molecules such as protons, acetylene, hydrogen cyanide and carbon monoxide or activate molecular dioxygen to produce hydroxylated products. The Ru(II)-diimine photosensitizers are hence able to deliver multiple electrons to metalloenzymes buried active sites, circumventing the need for the natural redox partners. In this review, we will highlight the key achievements of the light-driven biocatalysts, which stem from the extensive electron transfer investigations. This article is part of a Special Issue entitled Biodesign for Bioenergetics--the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson. PMID:26392147
NASA Astrophysics Data System (ADS)
Abellán, Antonio; Michoud, Clément; Jaboyedoff, Michel; Baillifard, François; Demierre, Jonathan; Carrea, Dario
2013-04-01
We present a model for ground displacements prediction using a transfer function. Model was mainly tested at the Barmasse rockslide (Valais, Switzerland) which is an active structurally-controlled instability formed by intensively deformed and metamorphosed mica schists. The kinematics of the slide, which currently threatens roads and inhabitants of the Bal de Bagnes Valley, is characterized by a continuous displacement with variable rates of displacements. Indeed, the velocity is strongly affected by external forces: a sharp increase in landslide velocity is observed with a short delay after every snow melting period and after each rainfall pulse. The instability is currently monitored by different remote sensing and in situ techniques (Terrestrial LiDAR, GB Radar and extensometers). In order to predict ground displacements, we developed a new model composed by two different parts: (a) calculation of the Effective Rainfall (Peff) and (b) modelling of the landslide velocity. First of all, Peff was obtained using Thornthwaite (1946) method, which estimates the water that infiltrates into the terrain as a function of the total precipitation, Real Evapo-Transpiration (ETR) and water recharge. Afterwards, the rates of displacement were modelled through a stochastic transfer function which links the Peff (input) with daily displacements (output). Model computes the displacement rates at each time lapse (e.g. one day) as a convolution of the above mentioned transfer function times daily effective rainfall during a certain time lapse (50 days in our case). The transfer function has two components: first component account for the sudden increase of landslide velocities after each rainfall pulse and second component account for the progressive decay. The variables of these functions were optimized in Matlab in order to minimize the error between the real and the modelled velocities. The model performance was assessed for two different response functions (following either
NASA Astrophysics Data System (ADS)
Basurto, Luis; Zope, Rajendra R.; Baruah, Tunna
2016-05-01
We report an electronic structure study of a multichromophoric molecular complex containing two of each borondipyrromethane dye, Zn-tetraphenyl-porphyrin, bisphenyl anthracene and a fullerene. The snowflake shaped molecule behaves like an antenna capturing photon at different frequencies and transferring the photon energy to the porphyrin where electron transfer occurs from the porphyrin to the fullerene. The study is performed within density functional formalism using large polarized Guassian basis sets (12,478 basis functions in total). The energies of the HOMO and LUMO states in the complex, as adjudged by the ionization potential and the electron affinity values, show significant differences with respect to their values in participating subunits in isolation. These differences are also larger than the variations of the ionization potential and electron affinity values observed in non-bonded C60-ZnTPP complexes in co-facial arrangement or end-on orientations. An understanding of the origin of these differences is obtained by a systematic study of the effect of structural strain, the presence of ligands, the effect of orbital delocalization on the ionization energy and the electron affinity. Finally, a few lowest charge transfer energies involving electronic transitions from the porphyrin component to the fullerene subunit of the complex are predicted.
Intercomparison of methods for image quality characterization. I. Modulation transfer function
Samei, Ehsan; Ranger, Nicole T.; Dobbins, James T. III; Chen, Ying
2006-05-15
The modulation transfer function (MTF) and the noise power spectrum (NPS) are widely recognized as the most relevant metrics of resolution and noise performance in radiographic imaging. These quantities have commonly been measured using various techniques, the specifics of which can have a bearing on the accuracy of the results. As a part of a study aimed at comparing the relative performance of different techniques, in this paper we report on a comparison of two established MTF measurement techniques: one using a slit test device [Dobbins et al., Med. Phys. 22, 1581-1593 (1995)] and another using a translucent edge test device [Samei et al., Med. Phys. 25, 102-113 (1998)], with one another and with a third technique using an opaque edge test device recommended by a new international standard (IEC 62220-1, 2003). The study further aimed to substantiate the influence of various acquisition and processing parameters on the estimated MTF. The slit test device was made of 2 mm thick Pb slabs with a 12.5 {mu}m opening. The translucent edge test device was made of a laminated and polished Pt{sub 0.9}Ir{sub 0.1} alloy foil of 0.1 mm thickness. The opaque edge test device was made of a 2 mm thick W slab. All test devices were imaged on a representative indirect flat-panel digital radiographic system using three published beam qualities: 70 kV with 0.5 mm Cu filtration, 70 kV with 19 mm Al filtration, and 74 kV with 21 mm Al filtration (IEC-RQA5). The latter technique was also evaluated in conjunction with two external beam-limiting apertures (per IEC 62220-1), and with the tube collimator limiting the beam to the same area achieved with the apertures. The presampled MTFs were deduced from the acquired images by Fourier analysis techniques, and the results analyzed for relative values and the influence of impacting parameters. The findings indicated that the measurement technique has a notable impact on the resulting MTF estimate, with estimates from the overall IEC method
Intercomparison of methods for image quality characterization. I. Modulation transfer function.
Samei, Ehsan; Ranger, Nicole T; Dobbins, James T; Chen, Ying
2006-05-01
The modulation transfer function (MTF) and the noise power spectrum (NPS) are widely recognized as the most relevant metrics of resolution and noise performance in radiographic imaging. These quantities have commonly been measured using various techniques, the specifics of which can have a bearing on the accuracy of the results. As a part of a study aimed at comparing the relative performance of different techniques, in this paper we report on a comparison of two established MTF measurement techniques: one using a slit test device [Dobbins et al., Med. Phys. 22, 1581-1593 (1995)] and another using a translucent edge test device [Samei et al., Med. Phys. 25, 102-113 (1998)], with one another and with a third technique using an opaque edge test device recommended by a new international standard (IEC 62220-1, 2003). The study further aimed to substantiate the influence of various acquisition and processing parameters on the estimated MTF. The slit test device was made of 2 mm thick Pb slabs with a 12.5 microm opening. The translucent edge test device was made of a laminated and polished Pt(0.9)Ir(0.1). alloy foil of 0.1 mm thickness. The opaque edge test device was made of a 2 mm thick W slab. All test devices were imaged on a representative indirect flat-panel digital radiographic system using three published beam qualities: 70 kV with 0.5 mm Cu filtration, 70 kV with 19 mm Al filtration, and 74 kV with 21 mm Al filtration (IEC-RQA5). The latter technique was also evaluated in conjunction with two external beam-limiting apertures (per IEC 62220-1), and with the tube collimator limiting the beam to the same area achieved with the apertures. The presampled MTFs were deduced from the acquired images by Fourier analysis techniques, and the results analyzed for relative values and the influence of impacting parameters. The findings indicated that the measurement technique has a notable impact on the resulting MTF estimate, with estimates from the overall IEC method 4
Wolfe, C.R.; Downie, J.D.; Lawson, J.K.
1996-06-27
The power spectral density (PSD) function is being employed to specify the surface finish and transmitted wavefront in the mid- spatial frequency regime for laser beam optics of the National Ignition Facility (NIF). The instrument used to measure the PSD is a phase measuring Fizeau interferometer. The phase map produced by the interferometer is digitally processed to create the PSD. Before one can use the PSD information, it is necessary to evaluate the fidelity of the interferometer spatial frequency response. Specifically, one must measure the overall transfer function of the instrument. To accomplish this, we perform a two-step ``calibration`` process. We first measure a known precision phase object with the interferometer and then compare the measured PSD to an ideal numerical simulation which represents the theoretical PSD. The square root of the ratio of the measured function to the simulation is defined as the transfer function of the instrument. We present experimental results for both reflective and transmissive test objects, including effects such as the test object orientation and longitudinal location in the interferometer cavity. We also evaluate the accuracy levels obtained using different test objects. 11 refs., 5 figs.
Range, Doppler and astrometric observables computed from Time Transfer Functions: a survey
NASA Astrophysics Data System (ADS)
Hees, A.; Bertone, S.; Le Poncin-Lafitte, C.; Teyssandier, P.
2015-08-01
Determining range, Doppler and astrometric observables is of crucial interest for modelling and analyzing space observations. We recall how these observables can be computed when the travel time of a light ray is known as a function of the positions of the emitter and the receiver for a given instant of reception (or emission). For a long time, such a function-called a reception (or emission) time transfer function has been almost exclusively calculated by integrating the null geodesic equations describing the light rays. However, other methods avoiding such an integration have been considerably developed in the last twelve years. We give a survey of the analytical results obtained with these new methods up to the third order in the gravitational constant G for a mass monopole. We briefly discuss the case of quasi-conjunctions, where higher-order enhanced terms must be taken into account for correctly calculating the effects. We summarize the results obtained at the first order in G when the multipole structure and the motion of an axisymmetric body is taken into account. We present some applications to on-going or future missions like Gaia and Juno. We give a short review of the recent works devoted to the numerical estimates of the time transfer functions and their derivatives.
The Time Transfer Functions: an efficient tool to compute range, Doppler and astrometric observables
NASA Astrophysics Data System (ADS)
Hees, A.; Bertone, S.; Le Poncin-Lafitte, C.; Teyssandier, P.
2015-12-01
Determining range, Doppler and astrometric observables is of crucial interest for modelling and analyzing space observations. We recall how these observables can be computed when the travel time of a light ray is known as a function of the positions of the emitter and the receiver for a given instant of reception (or emission). For a long time, such a function--called a reception (or emission) time transfer function--has been almost exclusively calculated by integrating the null geodesic equations describing the light rays. However, other methods avoiding such an integration have been considerably developped in the last twelve years. We give a survey of the analytical results obtained with these new methods up to the third order in the gravitational constant G for a mass monopole. We briefly discuss the case of quasi-conjunctions, where higher-order enhanced terms must be taken into account for correctly calculating the effects. We summarize the results obtained at the first order in G when the multipole structure and the motion of an axisymmetric body is taken into account. We present some applications to on-going or future missions like Gaia and Juno. We give a short review of the recent works devoted to the numerical estimates of the time transfer functions and their derivatives.
Tovar-Moll, Fernanda; Monteiro, Myriam; Andrade, Juliana; Bramati, Ivanei E.; Vianna-Barbosa, Rodrigo; Marins, Theo; Rodrigues, Erika; Dantas, Natalia; Behrens, Timothy E. J.; de Oliveira-Souza, Ricardo; Moll, Jorge; Lent, Roberto
2014-01-01
Why do humans born without the corpus callosum, the major interhemispheric commissure, lack the disconnection syndrome classically described in callosotomized patients? This paradox was discovered by Nobel laureate Roger Sperry in 1968, and has remained unsolved since then. To tackle the hypothesis that alternative neural pathways could explain this puzzle, we investigated patients with callosal dysgenesis using structural and functional neuroimaging, as well as neuropsychological assessments. We identified two anomalous white-matter tracts by deterministic and probabilistic tractography, and provide supporting resting-state functional neuroimaging and neuropsychological evidence for their functional role in preserved interhemispheric transfer of complex tactile information, such as object recognition. These compensatory pathways connect the homotopic posterior parietal cortical areas (Brodmann areas 39 and surroundings) via the posterior and anterior commissures. We propose that anomalous brain circuitry of callosal dysgenesis is determined by long-distance plasticity, a set of hardware changes occurring in the developing brain after pathological interference. So far unknown, these pathological changes somehow divert growing axons away from the dorsal midline, creating alternative tracts through the ventral forebrain and the dorsal midbrain midline, with partial compensatory effects to the interhemispheric transfer of cortical function. PMID:24821757
Tovar-Moll, Fernanda; Monteiro, Myriam; Andrade, Juliana; Bramati, Ivanei E; Vianna-Barbosa, Rodrigo; Marins, Theo; Rodrigues, Erika; Dantas, Natalia; Behrens, Timothy E J; de Oliveira-Souza, Ricardo; Moll, Jorge; Lent, Roberto
2014-05-27
Why do humans born without the corpus callosum, the major interhemispheric commissure, lack the disconnection syndrome classically described in callosotomized patients? This paradox was discovered by Nobel laureate Roger Sperry in 1968, and has remained unsolved since then. To tackle the hypothesis that alternative neural pathways could explain this puzzle, we investigated patients with callosal dysgenesis using structural and functional neuroimaging, as well as neuropsychological assessments. We identified two anomalous white-matter tracts by deterministic and probabilistic tractography, and provide supporting resting-state functional neuroimaging and neuropsychological evidence for their functional role in preserved interhemispheric transfer of complex tactile information, such as object recognition. These compensatory pathways connect the homotopic posterior parietal cortical areas (Brodmann areas 39 and surroundings) via the posterior and anterior commissures. We propose that anomalous brain circuitry of callosal dysgenesis is determined by long-distance plasticity, a set of hardware changes occurring in the developing brain after pathological interference. So far unknown, these pathological changes somehow divert growing axons away from the dorsal midline, creating alternative tracts through the ventral forebrain and the dorsal midbrain midline, with partial compensatory effects to the interhemispheric transfer of cortical function. PMID:24821757
Functional Transfer of Salmonella Pathogenicity Island 2 to Salmonella bongori and Escherichia coli
Hansen-Wester, Imke; Chakravortty, Dipshikha; Hensel, Michael
2004-01-01
The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to translocate a set of effector proteins into the host cell, which modify host cell functions, enabling intracellular survival and replication of the bacteria. We sought to determine whether specific functions of the SPI2-encoded T3SS can be transferred to heterologous hosts Salmonella bongori and Escherichia coli Mutaflor, species that lack the SPI2 locus and loci encoding effector proteins. The SPI2 virulence locus was cloned and functionally expressed in S. bongori and E. coli. Here, we demonstrate that S. bongori harboring the SPI2 locus is capable of secretion of SPI2 substrate proteins under culture conditions, as well as of translocation of effector proteins under intracellular conditions. An SPI2-mediated cellular phenotype was induced by S. bongori harboring the SPI2 if the sifA locus was cotransferred. An interference with the host cell microtubule cytoskeleton, a novel SPI2-dependent phenotype, was observed in epithelial cells infected with S. bongori harboring SPI2 without additional effector genes. S. bongori harboring SPI2 showed increased intracellular persistence in a cell culture model, but SPI2 transfer was not sufficient to confer to S. bongori systemic pathogenicity in a murine model. Transfer of SPI2 to heterologous hosts offers a new tool for the study of SPI2 functions and the phenotypes of individual effectors. PMID:15102800
Modulation transfer function cascade model for a sampled IR imaging system.
de Luca, L; Cardone, G
1991-05-01
The performance of the infrared scanning radiometer (IRSR) is strongly stressed in convective heat transfer applications where high spatial frequencies in the signal that describes the thermal image are present. The need to characterize more deeply the system spatial resolution has led to the formulation of a cascade model for the evaluation of the actual modulation transfer function of a sampled IR imaging system. The model can yield both the aliasing band and the averaged modulation response for a general sampling subsystem. For a line scan imaging system, which is the case of a typical IRSR, a rule of thumb that states whether the combined sampling-imaging system is either imaging-dependent or sampling-dependent is proposed. The model is tested by comparing it with other noncascade models as well as by ad hoc measurements performed on a commercial digitized IRSR. PMID:20700340
NASA Astrophysics Data System (ADS)
Burkhart, Blakesley; Ossenkopf, V.; Lazarian, A.; Stutzki, J.
2013-07-01
We study the effects of radiative transfer on the probability distribution functions (PDFs) of simulations of magnetohydrodynamic turbulence in the widely studied 13CO 2-1 transition. We find that the integrated intensity maps generally follow a log-normal distribution, with the cases that have τ ≈ 1 best matching the PDF of the column density. We fit a two-dimensional variance-sonic Mach number relationship to our logarithmic PDFs of the form \\sigma _{\\ln (\\Sigma /\\Sigma _0)}^2=A\\times \\ln (1+b^2{\\cal M}_s^2) and find that, for parameter b = 1/3, parameter A depends on the radiative transfer environment. We also explore the variance, skewness, and kurtosis of the linear PDFs finding that higher moments reflect both higher sonic Mach number and lower optical depth. Finally, we apply the Tsallis incremental PDF function and find that the fit parameters depend on both Mach numbers, but also are sensitive to the radiative transfer parameter space, with the τ ≈ 1 case best fitting the incremental PDF of the true column density. We conclude that, for PDFs of low optical depth cases, part of the gas is always subthermally excited so that the spread of the line intensities exceeds the spread of the underlying column densities and hence the PDFs do not reflect the true column density. Similarly, PDFs of optically thick cases are dominated by the velocity dispersion and therefore do not represent the true column density PDF. Thus, in the case of molecules like carbon monoxide, the dynamic range of intensities, structures observed, and, consequently, the observable PDFs are less determined by turbulence and more often determined by radiative transfer effects.
Uncertainty of Monetary Valued Ecosystem Services - Value Transfer Functions for Global Mapping.
Schmidt, Stefan; Manceur, Ameur M; Seppelt, Ralf
2016-01-01
Growing demand of resources increases pressure on ecosystem services (ES) and biodiversity. Monetary valuation of ES is frequently seen as a decision-support tool by providing explicit values for unconsidered, non-market goods and services. Here we present global value transfer functions by using a meta-analytic framework for the synthesis of 194 case studies capturing 839 monetary values of ES. For 12 ES the variance of monetary values could be explained with a subset of 93 study- and site-specific variables by utilizing boosted regression trees. This provides the first global quantification of uncertainties and transferability of monetary valuations. Models explain from 18% (water provision) to 44% (food provision) of variance and provide statistically reliable extrapolations for 70% (water provision) to 91% (food provision) of the terrestrial earth surface. Although the application of different valuation methods is a source of uncertainty, we found evidence that assuming homogeneity of ecosystems is a major error in value transfer function models. Food provision is positively correlated with better life domains and variables indicating positive conditions for human well-being. Water provision and recreation service show that weak ownerships affect valuation of other common goods negatively (e.g. non-privately owned forests). Furthermore, we found support for the shifting baseline hypothesis in valuing climate regulation. Ecological conditions and societal vulnerability determine valuation of extreme event prevention. Valuation of habitat services is negatively correlated with indicators characterizing less favorable areas. Our analysis represents a stepping stone to establish a standardized integration of and reporting on uncertainties for reliable and valid benefit transfer as an important component for decision support. PMID:26938447
Burkhart, Blakesley; Lazarian, A.; Ossenkopf, V.; Stutzki, J.
2013-07-10
We study the effects of radiative transfer on the probability distribution functions (PDFs) of simulations of magnetohydrodynamic turbulence in the widely studied {sup 13}CO 2-1 transition. We find that the integrated intensity maps generally follow a log-normal distribution, with the cases that have {tau} Almost-Equal-To 1 best matching the PDF of the column density. We fit a two-dimensional variance-sonic Mach number relationship to our logarithmic PDFs of the form {sigma}{sub ln}{sup 2}{sub ({Sigma}/{Sigma}0}) = A x ln(1+b{sup 2}M{sub s}{sup 2}) and find that, for parameter b = 1/3, parameter A depends on the radiative transfer environment. We also explore the variance, skewness, and kurtosis of the linear PDFs finding that higher moments reflect both higher sonic Mach number and lower optical depth. Finally, we apply the Tsallis incremental PDF function and find that the fit parameters depend on both Mach numbers, but also are sensitive to the radiative transfer parameter space, with the {tau} Almost-Equal-To 1 case best fitting the incremental PDF of the true column density. We conclude that, for PDFs of low optical depth cases, part of the gas is always subthermally excited so that the spread of the line intensities exceeds the spread of the underlying column densities and hence the PDFs do not reflect the true column density. Similarly, PDFs of optically thick cases are dominated by the velocity dispersion and therefore do not represent the true column density PDF. Thus, in the case of molecules like carbon monoxide, the dynamic range of intensities, structures observed, and, consequently, the observable PDFs are less determined by turbulence and more often determined by radiative transfer effects.
Uncertainty of Monetary Valued Ecosystem Services – Value Transfer Functions for Global Mapping
Schmidt, Stefan; Manceur, Ameur M.; Seppelt, Ralf
2016-01-01
Growing demand of resources increases pressure on ecosystem services (ES) and biodiversity. Monetary valuation of ES is frequently seen as a decision-support tool by providing explicit values for unconsidered, non-market goods and services. Here we present global value transfer functions by using a meta-analytic framework for the synthesis of 194 case studies capturing 839 monetary values of ES. For 12 ES the variance of monetary values could be explained with a subset of 93 study- and site-specific variables by utilizing boosted regression trees. This provides the first global quantification of uncertainties and transferability of monetary valuations. Models explain from 18% (water provision) to 44% (food provision) of variance and provide statistically reliable extrapolations for 70% (water provision) to 91% (food provision) of the terrestrial earth surface. Although the application of different valuation methods is a source of uncertainty, we found evidence that assuming homogeneity of ecosystems is a major error in value transfer function models. Food provision is positively correlated with better life domains and variables indicating positive conditions for human well-being. Water provision and recreation service show that weak ownerships affect valuation of other common goods negatively (e.g. non-privately owned forests). Furthermore, we found support for the shifting baseline hypothesis in valuing climate regulation. Ecological conditions and societal vulnerability determine valuation of extreme event prevention. Valuation of habitat services is negatively correlated with indicators characterizing less favorable areas. Our analysis represents a stepping stone to establish a standardized integration of and reporting on uncertainties for reliable and valid benefit transfer as an important component for decision support. PMID:26938447
Skjolding, L M; Winther-Nielsen, M; Baun, A
2014-12-01
The potential uptake and trophic transfer of nanoparticles (NP) is not well understood so far and for ZnO NP the data presented in peer-reviewed literature is limited. In this paper the influence of surface functionalization on the uptake and depuration behavior of ZnO NP, ZnO-OH NP and ZnO-octyl NP in D. magna was studied. Bulk ZnO particles (≤5 μm) and ZnCl2 were used as references for uptake of particles and dissolved species of Zn, respectively. Furthermore, the trophic transfer of ZnO NP and ZnO-octyl NP from daphnids (Daphnia magna) to zebra fish (Danio rerio) was studied. For ZnO NP and ZnO-octyl NP fast uptakes in D. magna were observed, whereas no measurable uptake took place for ZnO-OH NP. Lower body burden of ZnCl2 was found compared to both ZnO NP and ZnO-octyl. Contrary, the body burden for bulk ZnO was higher than that of ZnO NP but lower than ZnO-octyl. The higher body burdens found for functionalized ZnO-octyl NP than for non-functionalized ZnO NP showed that that the functionalization of the NP has a high influence on the uptake and depuration behavior. Though no mortality was observed, the resulting body burdens were 9.6 times (ZnO NP) and 47 times (ZnO-octyl NP) higher than toxic levels reported for zinc in D. magna. Consequently, the zinc recovered in the animals was not solely due to soluble zinc, but agglomerates/aggregates of ZnO NP or ZnO-octyl NP contributed to the body burdens. The trophic transfer study showed uptake of both ZnO NP and ZnO-octyl NP reaching more than tenfold higher levels than those obtained through aqueous exposure in other studies. This study contributes to expand the available data on uptake behavior of differently functionalized ZnO NP in D. magna and the potential trophic transfer from zooplankton to fish. PMID:25456224
Combined parameter and function estimation in heat transfer with application to contact conductance
NASA Astrophysics Data System (ADS)
Beck, J. V.
1988-11-01
This paper discusses parameter estimation, function estimation, and a combination of the two. An example of parameter estimation is the determination of thermal conductivity of solids from transient temperature measurements. An example of function estimation is the inverse heat conduction problem, which uses transient temperature measurements to determine the surface heat flux history. The examples used herein involve the determination of the thermal contact conductance. Two sets of very good data are analyzed. One set of steady-state data was obtained by Antonetti and Eid (1987). The other set was obtained by Moses and Johnson (1986) under transient conditions for periodic contact. Both sets of data are used to illustrate parameter, function, and combined estimation. It is demonstrated that the proposed methods are more powerful then commonly accepted methods. Many other heat transfer problems can be treated using the proposed techniques.
Katrangi, Eyad; D'Souza, Gerard; Boddapati, Sarathi V; Kulawiec, Mariola; Singh, Keshav K; Bigger, Brian; Weissig, Volkmar
2007-12-01
Mitochondrial DNA mutations are the direct cause of several physiological disorders and are also associated with the aging process. The modest progress made over the past two decades towards manipulating the mitochondrial genome and understanding its function within living mammalian cells means that cures for mitochondrial DNA mutations are still elusive. Here, we report that transformed mammalian cells internalize exogenous isolated mitochondria upon simple co-incubation. We first demonstrate the physical presence of internalized mitochondria within recipient cells using fluorescence microscopy. Second, we show that xenogenic transfer of murine mitochondria into human cells lacking functional mitochondria can functionally restore respiration in cells lacking mtDNA. Third, utilizing the natural competence of isolated mitochondria to take up linear DNA molecules, we demonstrate the feasibility of using cellular internalization of isolated exogenous mitochondria as a potential tool for studying mitochondrial genetics in living mammalian cells. PMID:18069915
NASA Technical Reports Server (NTRS)
Onken, R.
1972-01-01
Two simple methods are outlined for evaluating the effect of transfer-function zeros on the system time response. The pole effects can also be evaluated. These methods are useful for simplified analysis or creating design criteria in terms of desirable regions of pole-zero locations. The type of transfer function studied is limited to those linear systems. Corresponding to ordinary longitudinal or lateral aircraft transfer functions, the denominator polynomial is of fourth order and the numerator of third order at most. With the longitudinal motion of the aircraft as an example, the methods are used in the evaluation of optimal regulator control with respect to a particular performance index structure.
Sunder, Kaushik; Gan, Woon-Seng; Tan, Ee-Leng
2015-07-01
The veracity of virtual audio is degraded by the use of non-individualized head-related transfer functions (HRTFs) due to the introduction of front-back, elevation confusions, and timbral coloration. Hence, an accurate reproduction of spatial sound demands the use of individualized HRTFs. Measuring distance-dependent individualized HRTFs can be extremely tedious, since it requires precise measurements at several distances in the proximal region (<1 m) for each individual. This paper proposes a technique to model distance-dependent individualized HRTFs in the horizontal plane using "frontal projection headphones playback" that does not require individualized measurements. The frontal projection headphones [Sunder, Tan, and Gan (2013). J. Audio Eng. Soc. 61, 989-1000] project the sound directly onto the pinnae from the front, and thus inherently create listener's idiosyncratic pinna cues at the eardrum. Perceptual experiments were conducted to investigate cues (auditory parallax and interaural level differences) that aid distance perception in anechoic conditions. Interaural level differences were identified as the prominent cue for distance perception and a spherical head model was used to model these distance-dependent features. Detailed psychophysical experiments revealed that the modeled distance-dependent individualized HRTFs exhibited localization performance close to the measured distance-dependent individualized HRTFs for all subjects. PMID:26233016
Ziegelwanger, Harald; Majdak, Piotr; Kreuzer, Wolfgang
2015-01-01
Head-related transfer functions (HRTFs) can be numerically calculated by applying the boundary element method on the geometry of a listener’s head and pinnae. The calculation results are defined by geometrical, numerical, and acoustical parameters like the microphone used in acoustic measurements. The scope of this study was to estimate requirements on the size and position of the microphone model and on the discretization of the boundary geometry as triangular polygon mesh for accurate sound localization. The evaluation involved the analysis of localization errors predicted by a sagittal-plane localization model, the comparison of equivalent head radii estimated by a time-of-arrival model, and the analysis of actual localization errors obtained in a sound-localization experiment. While the average edge length (AEL) of the mesh had a negligible effect on localization performance in the lateral dimension, the localization performance in sagittal planes, however, degraded for larger AELs with the geometrical error as dominant factor. A microphone position at an arbitrary position at the entrance of the ear canal, a microphone size of 1 mm radius, and a mesh with 1 mm AEL yielded a localization performance similar to or better than observed with acoustically measured HRTFs. PMID:26233020
Roseman, A M; Neumann, K
2003-08-01
Digitisation of images recorded on film is a crucial part of data acquisition in electron microscopy, particularly for electron cryo-microscopy of biological specimens where the contrast and signal-to-noise ratio are low. A quantitative method to evaluate and compare the quality of densitometers, as measured by the modulation transfer function (MTF), is described here. The densitometer is modelled as a linear system, the output being the convolution of the input image and a point spread function. The MTF is the magnitude of the Fourier transform of the point spread function. The relative MTF describes the quality of signal transfer with spatial frequency. It is important that fine structural details in the micrograph are digitised with a high value for the MTF which does not vary with direction. A test pattern has been generated by projecting an electron image of a grid pattern onto film. The film is scanned and a computer program measures the intensities of the diffraction orders of the repeating pattern. Three different scanners are compared, one is a point scanner and the other two are line scanners. The test can be used to check if a scanner is set up optimally, and how it compares with another scanner. PMID:12672572
NASA Astrophysics Data System (ADS)
Bordes, C.; Sénéchal, P.; Barrière, J.; Brito, D.; Normandin, E.; Jougnot, D.
2015-03-01
Seismic waves propagating in a porous medium, under favourable conditions, generate measurable electromagnetic fields due to electrokinetic effects. It has been proposed, following experimental and numerical studies, that these so-called `seismoelectromagnetic' couplings depend on pore fluid properties. The theoretical frame describing these phenomena are based on the original Biot's theory, assuming that pores are fluid-filled. We study here the impact of a partially saturated medium on amplitudes of those seismoelectric couplings by comparing experimental data to an effective fluid model. We have built a 1-m-length-scale experiment designed for imbibition and drainage of an homogeneous silica sand; the experimental set-up includes a seismic source, accelerometers, electric dipoles and capacitance probes in order to monitor seismic and seismoelectric fields during water saturation. Apparent velocities and frequency spectra (in the kiloHertz range) are derived from seismic and electrical measurements during experiments in varying saturation conditions. Amplitudes of seismic and seismoelectric waves and their ratios (i.e. transfer functions) are discussed using a spectral analysis performed by continuous wavelet transform. The experiments reveal that amplitude ratios of seismic to coseismic electric signals remain rather constant as a function of the water saturation in the Sw = [0.2-0.9] range, consistently with theoretically predicted transfer functions.
[Effect of spectrum distortion on modulation transfer function in imaging fiber-optic spectrometer].
Cheng, Xin; Wang, Jing; Zhang, Bao; Hong, Yong-Feng
2011-10-01
Imaging fiber bundles were introduced to dispersion imaging spectrometer and substituted for slit, connecting the telescope and spectrometer to yield the imaging fiber-optic spectrometer. It is a double sampling system, the misalignment between image of optical fiber and detector pixel has arisen because of the spectrum distortion of spectrometer, which affected the second sampling process, and the modulation transfer function (MTF) therefore degraded. Optical transfer function of sampling process was derived from line spread function. The effect of spectrum distortion on system MTF was analyzed, and a model evaluating the MTF of imaging fiber-optic spectrometer was developed. Compared to the computation model of MTF of slit imaging spectrometer, a MTF item of sampling by optical fiber and a MTF item of misalignment arising from spectrum distortion were added in this model. Employing this, the MTF of an airborne imaging fiber-optic spectrometer for visible near infrared band was evaluated. The approach ro deriving and developing the MTF model has a reference signification for the computation of MTF of double sampling system, which can direct the design of imaging fiber-optic spectrometer also. PMID:22250572
NASA Astrophysics Data System (ADS)
Eismann, Michael T.; LeMaster, Daniel A.
2013-04-01
An aerosol modulation transfer function (MTF) model is developed to assess the impact of aerosol scattering on passive long-range imaging sensors. The methodology extends from previous work to explicitly address imaging scenarios with a nonuniform distribution of scattering characteristics over the propagation path and incorporates the moderate resolution transfer code database of aerosol cross-section and phase function characteristics in order to provide an empirical foundation for realistic quantitative MTF assessments. The resulting model is compared with both predictions from a Monte-Carlo scattering simulation and a scene-derived MTF estimate from an empirical image, with reasonable agreement in both cases. Application to long-range imaging situations at both visible and infrared wavelengths indicates that the magnitude and functional form of the aerosol MTF differ significantly from other contributors to the composite system MTF. Furthermore, the image-quality impact is largely radiometric in the sense that the contrast reduction is approximately independent of spatial frequency, and image blur is practically negligible.
Yu, Jintao; Liang, Yi; Thompson, Simon; Cull, Grant; Wang, Lin
2014-01-01
The aim of the study was to establish a parametric transfer function to describe the relationship between ocular perfusion pressure (OPP) and blood flow (BF) in the optic nerve head (ONH). A third-order parametric theoretical model was proposed to describe the ONH OPP-BF relationship within the lower OPP range of the autoregulation curve (< 80 mmHg) based on experimentally induced BF response to a rapid intraocular pressure (IOP) increase in 6 rhesus monkeys. The theoretical and actual data fitted well and suggest that this parametric third-order transfer function can effectively describe both the linear and nonlinear feature in dynamic and static autoregulation in the ONH within the OPP range studied. It shows that the BF autoregulation fully functions when the OPP was > 40 mmHg and becomes incomplete when the OPP was < 40 mmHg. This model may be used to help investigating the features of autoregulation in the ONH under different experimental conditions. PMID:24665355
Resist-based measurement of contrast transfer function in a 0.3-NAmicrofield optic
Cain, Jason P.; Naulleau, Patrick; Spanos, Costas J.
2005-01-11
Although extreme ultraviolet (EUV) lithography offers the possibility of very high-resolution patterning, the projection optics must be of extremely high quality in order to meet this potential. One key metric of the projection optic quality is the contrast transfer function (CTF), which is a measure of the aerial image contrast as a function of pitch. A static microfield exposure tool based on the 0.3-NA MET optic and operating at a wavelength of 13.5 nm has been installed at the Advanced Light Source, a synchrotron facility at the Lawrence Berkeley National Laboratory. This tool provides a platform for a wide variety of research into EUV lithography. In this work we present resist-based measurements of the contrast transfer function for the MET optic. These measurements are based upon line/space patterns printed in several different EUV photoresists. The experimental results are compared with the CTF in aerial-image simulations using the aberrations measured in the projection optic using interferometry. In addition, the CTF measurements are conducted for both bright-field and dark-field mask patterns. Finally, the orientation dependence of the CTF is measured in order to evaluate the effect of non-rotationally symmetric lens aberrations. These measurements provide valuable information in interpreting the results of other experiments performed using the MET and similar systems.
Line-ratio based ring artifact correction method using transfer function
NASA Astrophysics Data System (ADS)
Oh, Daejoong; Hwang, Dosik; Kim, Younguk
2016-03-01
Computed tomography (CT) has been used for medical purposes. However there are many artifacts at CT images and that makes distorted image. Ring artifact is caused by non-uniform sensitivity of detectors and makes ring shape artifact. Line-ratio method was proposed to solve the problem however there are some problem at specific case. Therefore we propose advanced method to correct ring artifact using transfer function. As a result, ring artifacts can be removed at more global cases. Simulation data shows the proposed method outperforms the conventional line-ratio method.
NASA Astrophysics Data System (ADS)
Wu, Yongwei; Xiong, Lei; Qin, Xiaokang; Wang, Zhengyue; Ding, Bei; Ren, Huan; Pi, Xiaolong
2015-07-01
In this work, polyacrylonitrile (PAN)-based carbon fibers (CF) were chemically modified with poly (glycidyl methacrylate) (PGMA) via atom transfer radical polymerization (ATRP) to improve the interaction between the CF and polymer matrix. The FT-IR, TGA, and XPS were used to determine the chemical structure of the resulting products and the quantities of PGMA chains grafted from the CF surface. The experimental results confirm that the CF surface was functionalized and glycidyl methacrylate was graft-polymerized onto the CF, and the grafting content of polymer could reach 10.2%.
Transfer-function-parameter estimation from frequency response data: A FORTRAN program
NASA Technical Reports Server (NTRS)
Seidel, R. C.
1975-01-01
A FORTRAN computer program designed to fit a linear transfer function model to given frequency response magnitude and phase data is presented. A conjugate gradient search is used that minimizes the integral of the absolute value of the error squared between the model and the data. The search is constrained to insure model stability. A scaling of the model parameters by their own magnitude aids search convergence. Efficient computer algorithms result in a small and fast program suitable for a minicomputer. A sample problem with different model structures and parameter estimates is reported.
Birch, Gabriel Carisle; Griffin, John Clark
2015-01-01
The horizontal television lines (HTVL) metric has been the primary quantity used by division 6000 related to camera resolution for high consequence security systems. This document shows HTVL measurements are fundamen- tally insufficient as a metric to determine camera resolution, and propose a quantitative, standards based methodology by measuring the camera system modulation transfer function (MTF), the most common and accepted metric of res- olution in the optical science community. Because HTVL calculations are easily misinterpreted or poorly defined, we present several scenarios in which HTVL is frequently reported, and discuss their problems. The MTF metric is discussed, and scenarios are presented with calculations showing the application of such a metric.
Modulation transfer function determination of video capture cards by speckle patterns
NASA Astrophysics Data System (ADS)
Pozo, Antonio M.; Castro, José J.; Rubiño, Manuel
2012-10-01
Today, video cameras connected to frame grabbers or video capture cards (VCCs) are used in many applications such as traffic control, surveillance, medical systems or machine vision. In this work, we present a method for determining the spatial-frequency response of VCCs. This method is based on the modulation transfer function (MTF) determination from speckle patterns using a low-cost experimental setup. We have evaluated and compared three different VCCs. The three VCCs produce an amplification (boost) in the horizontal MTF in a different spatial-frequency range, also differing in the maximum amplification value.
Ground Test of the Urine Processing Assembly for Accelerations and Transfer Functions
NASA Technical Reports Server (NTRS)
Houston, Janice; Almond, Deborah F. (Technical Monitor)
2001-01-01
This viewgraph presentation gives an overview of the ground test of the urine processing assembly for accelerations and transfer functions. Details are given on the test setup, test data, data analysis, analytical results, and microgravity assessment. The conclusions of the tests include the following: (1) the single input/multiple output method is useful if the data is acquired by tri-axial accelerometers and inputs can be considered uncorrelated; (2) tying coherence with the matrix yields higher confidence in results; (3) the WRS#2 rack ORUs need to be isolated; (4) and future work includes a plan for characterizing performance of isolation materials.
DC trains and Pc3s: Source effects in mid-latitude geomagnetic transfer functions
Egbert, G.D.; Eisel, M.; Boyde, O.S.; Morrison, H.F.
1999-10-01
Magnetotelluric (MT) data from two sites 150 and 300 km southeast of San Francisco, California (geomagnetic dipole latitude: 43 degrees, L approximately 1.9) show that the usual MT assumption of spatially uniform external magnetic fields is violated to a significant degree in the period range 10-30 s. Inter-station transfer functions exhibit large systematic:temporal variations which are consistent with a combination of two distinct sources: electromagnetic noise due to the San Francisco Bay Area Rapid Transit (BART) DC electric railway, and Pc3 geomagnetic pulsations. There is a suggestion in the data that some of the Pc activity may actually be excited by BART.
Comparison of beam-position-transfer functions using circular beam-position monitors
Gilpatrick, J.D.
1997-10-01
A cylindrical beam-position monitor (BPM) used in many accelerator facilities has four electrodes on which beam-image currents induce bunched-beam signals. These probe-electrode signals are geometrically configured to provide beam-position information about two orthogonal axes. An electronic processor performs a mathematical transfer function (TF) on these BPM-electrode signals to produce output signals whose time-varying amplitude is proportional to the beam`s vertical and horizontal position. This paper will compare various beam-position TFs using both pencil beams and will further discuss how diffuse beams interact with some of these TFs.
Site Transfer Functions of Three-Component Ground Motion in Western Turkey
NASA Astrophysics Data System (ADS)
Ozgur Kurtulmus, Tevfik; Akyol, Nihal; Camyildiz, Murat; Gungor, Talip
2015-04-01
Because of high seismicity accommodating crustal deformation and deep graben structures, on which have, urbanized and industrialized large cities in western Turkey, the importance of site-specific seismic hazard assessments becomes more crucial. Characterizing source, site and path effects is important for both assessing the seismic hazard in a specific region and generation of the building codes/or renewing previous ones. In this study, we evaluated three-component recordings for micro- and moderate-size earthquakes with local magnitudes ranging between 2.0 and 5.6. This dataset is used for site transfer function estimations, utilizing two different spectral ratio approaches 'Standard Spectral Ratio-(SSR)' and 'Horizontal to Vertical Spectral Ratio-(HVSR)' and a 'Generalized Inversion Technique-(GIT)' to highlight site-specific seismic hazard potential of deep basin structures of the region. Obtained transfer functions revealed that the sites located near the basin edges are characterized by broader HVSR curves. Broad HVSR peaks could be attributed to the complexity of wave propagation related to significant 2D/3D velocity variations at the sediment-bedrock interface near the basin edges. Comparison of HVSR and SSR estimates for the sites located on the grabens showed that SSR estimates give larger values at lower frequencies which could be attributed to lateral variations in regional velocity and attenuation values caused by basin geometry and edge effects. However, large amplitude values of vertical component GIT site transfer functions were observed at varying frequency ranges for some of the stations. These results imply that vertical component of ground motion is not amplification free. Contamination of HVSR site transfer function estimates at different frequency bands could be related to complexities in the wave field caused by deep or shallow heterogeneities in the region such as differences in the basin geometries, fracturing and fluid saturation along
Study on utility of an approximated transfer function of dynamically tuned dry gyro
NASA Astrophysics Data System (ADS)
Shingu, H.; Otsuki, M.; Hayano, T.
The use of a dry gyro in analog rebalance loops is described and a method to improve the static and dynamic characteristics is presented. The transfer function is derived by transforming a generalized equation into the approximated form based on the design specifications of the mechanical parts. This approximation is proved to be reasonable by the result that the differences between the numerical solutions of a generalized equation and those of an approximated equation are less than 1.0%, and their mean values are less than 0.003%. Noninteracting control is analyzed and the stability conditions are investigated. A fundamental design conception for rebalance loops was established.
Full-Scale Turbofan-Engine Turbine-Transfer Function Determination Using Three Internal Sensors
NASA Technical Reports Server (NTRS)
Hultgren, Lennart S.
2012-01-01
Noise-source separation techniques, using three engine-internal sensors, are applied to existing static-engine test data to determine the turbine transfer function for the currently subdominant combustion noise. The results are used to assess the combustion-noise prediction capability of the Aircraft Noise Prediction Program (ANOPP) and an improvement to the combustion-noise module GECOR is suggested. The work was carried out in response to the NASA Fundamental Aeronautics Subsonic Fixed Wing Program s Reduced-Perceived-Noise Technical Challenge.
Track/train dynamics test report transfer function test. Volume 1: Test
NASA Technical Reports Server (NTRS)
Vigil, R. A.
1975-01-01
A description is presented of the transfer function test performed on an open hopper freight car loaded with 80 tons of coal. Test data and a post-test update of the requirements document and test procedure are presented. Included are a statement of the test objective, a description of the test configurations, test facilities, test methods, data acquisition/reduction operations, and a chronological test summary. An index to the data for the three test configurations (X, Y, and Z-axis tests) is presented along with test sequence, run number, test reference, and input parameters.
Physics of psychophysics: Stevens and Weber-Fechner laws are transfer functions of excitable media
NASA Astrophysics Data System (ADS)
Copelli, Mauro; Roque, Antônio C.; Oliveira, Rodrigo F.; Kinouchi, Osame
2002-06-01
Sensory arrays made of coupled excitable elements can improve both their input sensitivity and dynamic range due to collective nonlinear wave properties. This mechanism is studied in a neural network of electrically coupled (e.g., via gap junctions) elements subject to a Poisson signal process. The network response interpolates between a Weber-Fechner logarithmic law, and a Stevens power law depending on the relative refractory period of the cell. Therefore, these nonlinear transformations of the input level could be performed in the sensory periphery simply due to a basic property: the transfer function of excitable media.
Assessment of functional gametes in chickens after transfer of primordial germ cells.
Petitte, J N; Clark, M E; Etches, R J
1991-05-01
The ability of primordial germ cells (PGCs) transferred from donor to recipient embryos to form functional gametes was assessed using feather colour as a phenotypic marker. Donor primordial germ cells were obtained in blood samples taken from Dwarf White Leghorn embryos, homozygous for the dominant allele at the locus for 'dominant white' plumage (I), which had been incubated for 52 h. Blood samples containing PGCs were transferred by intravascular injection to Barred Plymouth Rock embryos (ii) incubated for 53, 72 and 96 h. Of the embryos which hatched, 28 were male and 31 were female. All chicks were raised to sexual maturity and test mated with Barred Plymouth Rock fowl. All of the 3117 offspring exhibited the typical Barred Plymouth Rock phenotype; no Barred Plymouth Rock x Dwarf White Leghorn chicks were obtained. The results of this study suggest that the frequency of transmission of the donor line genotype after PGC transfer must be improved for this technique to be useful for the routine development of transgenic poultry. PMID:2056493
A Functional Bacterium-to-Plant DNA Transfer Machinery of Rhizobium etli
Lacroix, Benoît; Citovsky, Vitaly
2016-01-01
Different strains and species of the soil phytopathogen Agrobacterium possess the ability to transfer and integrate a segment of DNA (T-DNA) into the genome of their eukaryotic hosts, which is mainly mediated by a set of virulence (vir) genes located on the bacterial Ti-plasmid that also contains the T-DNA. To date, Agrobacterium is considered to be unique in its capacity to mediate genetic transformation of eukaryotes. However, close homologs of the vir genes are encoded by the p42a plasmid of Rhizobium etli; this microorganism is related to Agrobacterium, but known only as a symbiotic bacterium that forms nitrogen-fixing nodules in several species of beans. Here, we show that R. etli can mediate functional DNA transfer and stable genetic transformation of plant cells, when provided with a plasmid containing a T-DNA segment. Thus, R. etli represents another bacterial species, besides Agrobacterium, that encodes a protein machinery for DNA transfer to eukaryotic cells and their subsequent genetic modification. PMID:26968003
An adapted modulation transfer function for x-ray backscatter radiography by selective detection
NASA Astrophysics Data System (ADS)
Sabri, Nissia; Dugan, Edward T.; Jacobs, Alan M.; Shedlock, Daniel
2007-09-01
The Modulation Transfer Function (MTF) is a quantitative function based on frequency resolution that characterizes imaging system performance. In this study, a new MTF methodology is investigated for application to Radiography by Selective Detection (RSD), an enhanced single-side x-ray Compton backscatter imaging (CBI) technique which detects selected scatter components. The RSD imaging modality is a unique type of real-time radiography that uses a set of fin and sleeve collimators to preferentially select different components of the x-ray backscattered field. Radiography by selective detection has performed successfully in different non-destructive evaluation (NDE) applications. A customized RSD imaging system was built at the University of Florida for inspection of the space shuttle external tank spray-on foam insulation (SOFI). The x-ray backscatter RSD imaging system has been successfully used for crack and corrosion detection in a variety of materials. The conventional transmission x-ray image quality characterization tools do not apply for RSD because of the different physical process involved. Thus, the main objective of this project is to provide an adapted tool for dynamic evaluation of RSD system image quality. For this purpose, an analytical model of the RSD imaging system response is developed and supported. Two approaches are taken for the MTF calculations: one using the Fourier Transform of a line spread function and the other one using a sine function pattern. Calibration and test targets are then designed according to this proposed model. A customized Matlab code using image contrast and digital curve recognition is developed to support the experimental data and provide the Modulation Transfer Functions for RSD.
Ishikawa, Fumihiro; Miyamoto, Kengo; Konno, Sho; Kasai, Shota; Kakeya, Hideaki
2015-12-18
A significant gap exists between protein engineering and enzymes used for the biosynthesis of natural products, largely because there is a paucity of strategies that rapidly detect active-site phenotypes of the enzymes with desired activities. Herein, we describe a proof-of-concept study of an enzyme-linked immunosorbent assay (ELISA) system for the adenylation (A) domains in nonribosomal peptide synthetases (NRPSs) using a combination of active site-directed probes coupled to a 5'-O-N-(aminoacyl)sulfamoyladenosine scaffold with a biotin functionality that immobilizes probe molecules onto a streptavidin-coated solid support. The recombinant NRPSs have a C-terminal His-tag motif that is targeted by an anti-6×His mouse antibody as the primary antibody and a horseradish peroxidase-linked goat antimouse antibody as the secondary antibody. These probes can selectively capture the cognate A domains by ligand-directed targeting. In addition, the ELISA technique detected A domains in the crude cell-free homogenates from the Escherichia coli expression systems. When coupled with a chromogenic substrate, the antibody-based ELISA technique can visualize probe-protein binding interactions, which provides accurate readouts of the A-domain functions in NRPS enzymes. To assess the ELISA-based engineering of the A domains of NRPSs, we reprogramed 2,3-dihydroxybenzoic acid (DHB)-activating enzyme EntE toward salicylic acid (Sal)-activating enzymes and investigated a correlation between binding properties for probe molecules and enzyme catalysts. We generated a mutant of EntE that displayed negligible loss in the kcat/Km value with the noncognate substrate Sal and a corresponding 48-fold decrease in the kcat/Km value with the cognate substrate DHB. The resulting 26-fold switch in substrate specificity was achieved by the replacement of a Ser residue in the active site of EntE with a Cys toward the nonribosomal codes of Sal-activating enzymes. Bringing a laboratory ELISA technique
Yashchuk, Valeriy V.; McKinney, Wayne R.; Takacs, Peter Z.
2008-05-19
We suggest and describe the use of a binary pseudo-random grating as a standard test surface for calibration of the modulation transfer function of microscopes. Results from calibration of a MicromapTM-570 interferometric microscope are presented.
Sandala, Gregory M.; Hopmann, Kathrin H.; Ghosh, Abhik
2011-01-01
structure. Significant improvements to the isomer shift calibrations are obtained for B3LYP and B3LYP* when geometries obtained with the OLYP functional are used. In addition, greatly improved performance of these functionals is found if the complete test set is grouped separately into Fe–NO and Fe–S complexes. Calibration fits including only Fe–NO complexes are found to be excellent, while those containing the non-nitrosyl Fe–S complexes alone are found to demonstrate less accurate correlations. Similar trends are also found with OLYP, OPBE, PW91, and BP86. Correlations between experimental and calculated QSs were also investigated. Generally, universal and separate Fe–NO and Fe–S fit parameters obtained to determine QSs are found to be of good to excellent quality for every density functional examined, especially if [Fe4(NO)4(μ3-S)4]− is removed from the test set. PMID:22039359
Self-assembly of intramolecular charge-transfer compounds into functional molecular systems.
Li, Yongjun; Liu, Taifeng; Liu, Huibiao; Tian, Mao-Zhong; Li, Yuliang
2014-04-15
Highly polarized compounds exhibiting intramolecular charge transfer (ICT) are used widely as nonlinear optical (NLO) materials and red emitters and in organic light emitting diodes. Low-molecular-weight donor/acceptor (D/A)-substituted ICT compounds are ideal candidates for use as the building blocks of hierarchically structured, multifunctional self-assembled supramolecular systems. This Account describes our recent studies into the development of functional molecular systems with well-defined self-assembled structures based on charge-transfer (CT) interactions. From solution (sensors) to the solid state (assembled structures), we have fully utilized intrinsic and stimulus-induced CT interactions to construct these functional molecular systems. We have designed some organic molecules capable of ICT, with diversity and tailorability, that can be used to develop novel self-assembled materials. These ICT organic molecules are based on a variety of simple structures such as perylene bisimide, benzothiadiazole, tetracyanobutadiene, fluorenone, isoxazolone, BODIPY, and their derivatives. The degree of ICT is influenced by the nature of both the bridge and the substituents. We have developed new methods to synthesize ICT compounds through the introduction of heterocycles or heteroatoms to the π-conjugated systems or through extending the conjugation of diverse aromatic systems via another aromatic ring. Combining these ICT compounds featuring different D/A units and different degrees of conjugation with phase transfer methodologies and solvent-vapor techniques, we have self-assembled various organic nanostructures, including hollow nanospheres, wires, tubes, and ribbonlike architectures, with controllable morphologies and sizes. For example, we obtained a noncentrosymmetric microfiber structure that possessed a permanent dipole along its fibers' long axis and a transition dipole perpendicular to it; the independent NLO responses of this material can be separated and
NASA Technical Reports Server (NTRS)
Rauchmiller, Robert F., Jr.; Schowengerdt, Robert A.
1988-01-01
This paper presents a method for measuring the Thematic Mapper (TM) imaging system point spread function (PSF) using TM imagery or a specially constructed target consisting of a two-dimensional array of approximate point sources of known dimensions and radiometric qualities. The target allows 16 separate point sources to be imaged simultaneously by the TM. The point sources were carefully placed on the ground so that their relative positions were known. Owing to sample-scene phasing, each imaged point source exhibits a different amount of blur in the digital image. The target pixels may then be recombined according to their known relative positions to form a single, sampled, nonaliased imaging system PSF. The modulation transfer function is then obtained as the modulus of the discrete Fourier transform of the PSF.
NASA Astrophysics Data System (ADS)
Lee, Y. C.; Thompson, H. M.; Gaskell, P. H.
2009-12-01
FILMPAR is a highly efficient and portable parallel multigrid algorithm for solving a discretised form of the lubrication approximation to three-dimensional, gravity-driven, continuous thin film free-surface flow over substrates containing micro-scale topography. While generally applicable to problems involving heterogeneous and distributed features, for illustrative purposes the algorithm is benchmarked on a distributed memory IBM BlueGene/P computing platform for the case of flow over a single trench topography, enabling direct comparison with complementary experimental data and existing serial multigrid solutions. Parallel performance is assessed as a function of the number of processors employed and shown to lead to super-linear behaviour for the production of mesh-independent solutions. In addition, the approach is used to solve for the case of flow over a complex inter-connected topographical feature and a description provided of how FILMPAR could be adapted relatively simply to solve for a wider class of related thin film flow problems. Program summaryProgram title: FILMPAR Catalogue identifier: AEEL_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEEL_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 530 421 No. of bytes in distributed program, including test data, etc.: 1 960 313 Distribution format: tar.gz Programming language: C++ and MPI Computer: Desktop, server Operating system: Unix/Linux Mac OS X Has the code been vectorised or parallelised?: Yes. Tested with up to 128 processors RAM: 512 MBytes Classification: 12 External routines: GNU C/C++, MPI Nature of problem: Thin film flows over functional substrates containing well-defined single and complex topographical features are of enormous significance, having a wide variety of engineering
Naming and Categorization in Young Children: IV: Listener Behavior Training and Transfer of Function
Horne, Pauline J; Hughes, J. Carl; Lowe, C. Fergus
2006-01-01
Following pretraining with everyday objects, 14 children aged from 1 to 4 years were trained, for each of three pairs of different arbitrary wooden shapes (Set 1), to select one stimulus in response to the spoken word /zog/, and the other to /vek/. When given a test for the corresponding tacts (“zog” and “vek”), 10 children passed, showing that they had learned common names for the stimuli, and 4 failed. All children were trained to clap to one stimulus of Pair 1 and wave to the other. All those who named showed either transfer of the novel functions to the remaining two pairs of stimuli in Test 1, or novel function comprehension for all three pairs in Test 2, or both. Three of these children next participated in, and passed, category match-to-sample tests. In contrast, all 4 children who had learned only listener behavior failed both the category transfer and category match-to-sample tests. When 3 of them were next trained to name the stimuli, they passed the category transfer and (for the 2 subjects tested) category match-to-sample tests. Three children were next trained on the common listener relations with another set of arbitrary stimuli (Set 2); all succeeded on the tact and category tests with the Set 2 stimuli. Taken together with the findings from the other studies in the series, the present experiment shows that (a) common listener training also establishes the corresponding names in some but not all children, and (b) only children who learn common names categorize; all those who learn only listener behavior fail. This is good evidence in support of the naming account of categorization. PMID:16673828
Santos, Elton J G; Wang, W L
2016-09-21
Understanding the microscopic mechanisms of electronic excitation in organic photovoltaic cells is a challenging problem in the design of efficient devices capable of performing sunlight harvesting. Here we develop and apply an ab initio approach based on time-dependent density functional theory and Ehrenfest dynamics to investigate photoinduced charge transfer in small organic molecules. Our calculations include mixed quantum-classical dynamics with ions moving classically and electrons quantum mechanically, where no experimental external parameter other than the material geometry is required. We show that the behavior of photocarriers in zinc phthalocyanine (ZnPc) and C60 systems, an effective prototype system for organic solar cells, is sensitive to the atomic orientation of the donor and the acceptor units as well as the functionalization of covalent molecules at the interface. In particular, configurations with the ZnPc molecules facing on C60 facilitate charge transfer between substrate and molecules that occurs within 200 fs. In contrast, configurations where ZnPc is tilted above C60 present extremely low carrier injection efficiency even at longer times as an effect of the larger interfacial potential level offset and higher energetic barrier between the donor and acceptor molecules. An enhancement of charge injection into C60 at shorter times is observed as binding groups connect ZnPc and C60 in a dyad system. Our results demonstrate a promising way of designing and controlling photoinduced charge transfer on the atomic level in organic devices that would lead to efficient carrier separation and maximize device performance. PMID:27314747
Bio-inspired direct patterning functional nanothin microlines: controllable liquid transfer.
Wang, Qianbin; Meng, Qingan; Wang, Pengwei; Liu, Huan; Jiang, Lei
2015-04-28
Developing a general and low-cost strategy that enables direct patterning of microlines with nanometer thickness from versatile liquid-phase functional materials and precise positioning of them on various substrates remains a challenge. Herein, with inspiration from the oriental wisdom to control ink transfer by Chinese brushes, we developed a facile and general writing strategy to directly pattern various functional microlines with homogeneous distribution and nanometer-scale thickness. It is demonstrated that the width and thickness of the microlines could be well-controlled by tuning the writing method, providing guidance for the adaptation of this technique to various systems. It is also shown that various functional liquid-phase materials, such as quantum dots, small molecules, polymers, and suspensions of nanoparticles, could directly write on the substrates with intrinsic physicochemical properties well-preserved. Moreover, this technique enabled direct patterning of liquid-phase materials on certain microdomains, even in multiple layered style, thus a microdomain localized chemical reaction and the patterned surface chemical modification were enabled. This bio-inspired direct writing device will shed light on the template-free printing of various functional micropatterns, as well as the integrated functional microdevices. PMID:25845024
NASA Astrophysics Data System (ADS)
Rinas, D.; Jia, J.; Zeichner, A.; Frei, S.
2013-07-01
Today EMC emissions of automotive components are often measured in anechoic chambers by an antenna at fixed position according to CISPR 25 (ALSE-method). The antenna voltage often cannot sufficiently describe the behaviour of the measured electronic components and systems. Furthermore space requirements and costs are very high for the ALSE-method. Field- and cable-scan methods combined with near-field to far-field transformation techniques might be a good alternative. Residual reflections from the walls, the metallic floor, the measuring table, interaction of the antenna with the environment, and other factors affect the measurements. Thus, models which only regard the current distribution for near- and far field calculation cannot produce results equal to a chamber measurement. In this paper methods for computing transfer functions for the substitution of EMC antenna measurements with field- and cable scans in a specified calibration area are introduced. To consider influences of the environment, the environment is characterized in a first step and included with transfer functions in the calculation process for the equivalent ALSE-field.
Hourdez, S; Lallier, F H; De Cian, M C; Green, B N; Weber, R E; Toulmond, A
2000-01-01
Alvinella pompejana is a tubicolous polychaete that dwells in the hottest part of the hydrothermal vent ecosystem in a highly variable mixture of vent (350 degrees C, anoxic, CO(2)- and sulfide-rich) and deep-sea (2 degrees C, mildly hypoxic) waters. This species has developed distinct-and specifically respiratory-adaptations to this challenging environment. An internal gas exchange system has recently been described, along with the report of an intracellular coelomic hemoglobin, in addition to the previously known extracellular vascular hemoglobin. This article reports the structure of coelomic hemoglobin and the functional properties of both hemoglobins in order to assess possible oxygen transfer. Coelomocytes contain a unique monomeric hemoglobin with a molecular weight of 14,810+/-1.5 Da, as determined by mass spectrometry. The functional properties of both hemoglobins are unexpectedly very similar under the same conditions of pH (6.1-8.2) and temperature (10 degrees -40 degrees C). The oxygen affinity of both proteins is relatively high (P50=0.66 Torr at 20 degrees C and pH 7), which facilitates oxygen uptake from the hypoxic environment. A strong Bohr effect (Phi ranging from -0.8 to -1.0) allows the release of oxygen to acidic tissues. Such similar properties imply a possible bidirectional transfer of oxygen between the two hemoglobins in the perioesophagal pouch, a mechanism that could moderate environmental variations of oxygen concentration and maintain brain oxygenation. PMID:10893176
Pressure transfer function of a JT15D nozzle due to acoustic and convected entropy fluctuations
NASA Technical Reports Server (NTRS)
Miles, J. H.
1982-01-01
An acoustic transmission matrix analysis of sound propagation in a variable area duct with and without flow is extended to include convected entropy fluctuations. The boundary conditions used in the analysis are a transfer function relating entropy and pressure at the nozzle inlet and the nozzle exit impedance. The nozzle pressure transfer function calculated is compared with JT15D turbofan engine nozzle data. The one dimensional theory for sound propagation in a variable area nozzle with flow but without convected entropy is good at the low engine speeds where the nozzle exit Mach number is low (M=0.2) and the duct exit impedance model is good. The effect of convected entropy appears to be so negligible that it is obscured by the inaccuracy of the nozzle exit impedance model, the lack of information on the magnitude of the convected entropy and its phase relationship with the pressure, and the scatter in the data. An improved duct exit impedance model is required at the higher engine speeds where the nozzle exit Mach number is high (M=0.56) and at low frequencies (below 120 Hz).
Chiu, Tai-Yin; Chiang, Hui-Ju K.; Huang, Ruei-Yang; Jiang, Jie-Hong R.; Fages, François
2015-01-01
The ability to engineer synthetic systems in the biochemical context is constantly being improved and has a profound societal impact. Linear system design is one of the most pervasive methods applied in control tasks, and its biochemical realization has been proposed by Oishi and Klavins and advanced further in recent years. However, several technical issues remain unsolved. Specifically, the design process is not fully automated from specification at the transfer function level, systems once designed often lack dynamic adaptivity to environmental changes, matching rate constants of reactions is not always possible, and implementation may be approximative and greatly deviate from the specifications. Building upon the work of Oishi and Klavins, this paper overcomes these issues by introducing a design flow that transforms a transfer-function specification of a linear system into a set of chemical reactions, whose input-output response precisely conforms to the specification. This system is implementable using the DNA strand displacement technique. The underlying configurability is embedded into primitive components and template modules, and thus the entire system is adaptive. Simulation of DNA strand displacement implementation confirmed the feasibility and superiority of the proposed synthesis flow. PMID:26352855
NASA Astrophysics Data System (ADS)
Astar, William
1996-06-01
Two apertures, a square slit (SS) and a diamond slit (DS), both zero'th-order magnitude transparencies with bandpass filters in their optical transfer functions (OTFs), are designed and optimized for the purpose of modulation transfer function (MTF) evaluation of detector arrays by means of laser speckle. The SS and DS apertures are compared to an existing design, the extended frequency aperture, and show, respectively, improvements of 464% and 58% in filter magnitude; improvements of -13.4% (a compromise) and 17% in bandwidth; and improvements of 627% and 423% in throughput, implying a greatly reduced laser power requirement. As a result, they should significantly enhance detector arrays' MTF evaluations and at a greatly reduced cost. The DS aperture possesses identical OTFs in both the horizontal and vertical directions, enabling MTF evaluation using the bandpass filters in those directions from the same speckle data frame--previously not possible. The DS aperture can be further modified to yield filter magnitude and bandwidth improvements of 111% and 40%, respectively; although becoming easier to fabricate, this modification would be a lower throughput improvement of 310% over the existing design.
Chiu, Tai-Yin; Chiang, Hui-Ju K; Huang, Ruei-Yang; Jiang, Jie-Hong R; Fages, François
2015-01-01
The ability to engineer synthetic systems in the biochemical context is constantly being improved and has a profound societal impact. Linear system design is one of the most pervasive methods applied in control tasks, and its biochemical realization has been proposed by Oishi and Klavins and advanced further in recent years. However, several technical issues remain unsolved. Specifically, the design process is not fully automated from specification at the transfer function level, systems once designed often lack dynamic adaptivity to environmental changes, matching rate constants of reactions is not always possible, and implementation may be approximative and greatly deviate from the specifications. Building upon the work of Oishi and Klavins, this paper overcomes these issues by introducing a design flow that transforms a transfer-function specification of a linear system into a set of chemical reactions, whose input-output response precisely conforms to the specification. This system is implementable using the DNA strand displacement technique. The underlying configurability is embedded into primitive components and template modules, and thus the entire system is adaptive. Simulation of DNA strand displacement implementation confirmed the feasibility and superiority of the proposed synthesis flow. PMID:26352855
Furihata, Kenji; Yamashita, Masato
2013-02-01
While occupational injury is associated with numerous individual and work-related risk factors, including long working hours and short sleep duration, the complex mechanisms causing such injuries are not yet fully understood. The relationship between the infrasound pressures of the tympanic membrane [ear canal pressure (ECP)], detected using an earplug embedded with a low-frequency microphone, and the carotid artery [carotid artery pressure (CAP)], detected using a stethoscope fitted with the same microphone, can be quantitatively characterized using systems analysis. The transfer functions of 40 normal workers (19 to 57 years old) were characterized, involving the analysis of 446 data points. The ECP waveform exhibits a pulsatile character with a slow respiratory component, which is superimposed on a biphasic recording that is synchronous with the cardiac cycle. The respiratory ECP waveform correlates with the instantaneous heart rate. The results also revealed that various fatigue-related risk factors may affect the mean magnitudes of the measured pressures and the delay transfer functions between CAP and ECP in the study population; these factors include systolic blood pressure, salivary amylase activity, age, sleep duration, postural changes, chronic fatigue, and pulse rate. PMID:23363133
The acoustical cues to sound location in the rat: Measurements of directional transfer functions
Koka, Kanthaiah; Read, Heather L.; Tollin, Daniel J.
2008-01-01
The acoustical cues for sound location are generated by spatial- and frequency-dependent filtering of propagating sound waves by the head and external ears. Although rats have been a common model system for anatomy, physiology, and psychophysics of localization, there have been few studies of the acoustical cues available to rats. Here, directional transfer functions (DTFs), the directional components of the head-related transfer functions, were measured in six adult rats. The cues to location were computed from the DTFs. In the frontal hemisphere, spectral notches were present for frequencies from ∼16 to 30 kHz; in general, the frequency corresponding to the notch increased with increases in source elevation and in azimuth toward the ipsilateral ear. The maximum high-frequency envelope-based interaural time differences (ITDs) were 130 μs, whereas low-frequency (<3.5 kHz) fine-structure ITDs were 160 μs; both types of ITDs were larger than predicted from spherical head models. Interaural level differences (ILDs) strongly depended on location and frequency. Maximum ILDs were <10 dB for frequencies <8 kHz and were as large as 20–40 dB for frequencies >20 kHz. Removal of the pinna eliminated the spectral notches, reduced the acoustic gain and ILDs, altered the acoustical axis, and reduced the ITDs. PMID:18537381
Electrical Transfer Function and Poling Mechanisms for Nonlinear Optical Polymer Modulators
NASA Technical Reports Server (NTRS)
Watson, Michael Dale
2004-01-01
Electro-Optic Polymers hold great promise in increased electro-optic coefficients as compared to their inorganic corollaries. Many researchers have focused on quantum chemistry to describe how the dipoles respond to temperature and electric fields. Much work has also been done for single layer films to confirm these results. For optical applications, waveguide structures are utilized to guide the optical waves in 3 layer stacks. Electrode poling is the only practical poling method for these structures. This research takes an electrical engineering approach to develop poling models and electrical and optical transfer functions of the waveguide structure. The key aspect of the poling model is the large boundary charge density deposited during the poling process. The boundary charge density also has a large effect on the electrical transfer function which is used to explain the transient response of the system. These models are experimentally verified. Exploratory experiment design is used to study poling parameters including time, temperature, and voltage. These studies verify the poling conditions for CLDX/APC and CLDZ/APEC guest host electro optic polymer films in waveguide stacks predicted by the theoretical developments.
Reducing individual differences in the external-ear transfer functions of the Mongolian gerbil
NASA Astrophysics Data System (ADS)
Maki, Katuhiro; Furukawa, Shigeto
2005-10-01
This study examines individual differences in the directional transfer functions (DTFs), the directional components of head-related transfer functions of gerbils, and seeks a method for reducing these differences. The difference between the DTFs of a given animal pair was quantified by the intersubject spectral difference (ISSD), which is the variance in the difference spectra of DTFs for frequencies between 5 and 45 kHz and for 361 source directions. An attempt was made to reduce the ISSD by scaling the DTFs of one animal in frequency and/or rotating the DTFs along the source coordinate sphere. The ISSD was reduced by a median of 12% after optimal frequency scaling alone, by a median of 19% after optimal spatial rotation alone, and by a median of 36% after simultaneous frequency scaling and spatial rotation. The optimal scaling factor (OSF) and the optimal coordinate rotation (OCR) correlated strongly with differences in head width and pinna angles (i.e., pinna inclination around the vertical and front-back axes), respectively. Thus, linear equations were derived to estimate the OSF and OCR from these anatomical measurements. The ISSD could be reduced by a median of 22% based on the estimated OSF and OCR.
Carbonell-Ballestero, Max; Duran-Nebreda, Salva; Montañez, Raúl; Solé, Ricard; Macía, Javier; Rodríguez-Caso, Carlos
2014-12-16
Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly adopted strategy is to fit data to Hill-shaped curves without considering the underlying molecular mechanisms. Here we provide a novel mathematical formalization that allows prediction of the global behavior of a synthetic device by considering the actual information from the involved biological parts. This is achieved by adopting an enzymology-like framework, where transfer functions are described in terms of their input affinity constant and maximal response. As a proof of concept, we characterize a set of Lux homoserine-lactone-inducible genetic devices with different levels of Lux receptor and signal molecule. Our model fits the experimental results and predicts the impact of the receptor's ribosome-binding site strength, as a tunable parameter that affects gene expression. The evolutionary implications are outlined. PMID:25404136
The acoustical cues to sound location in the rat: measurements of directional transfer functions.
Koka, Kanthaiah; Read, Heather L; Tollin, Daniel J
2008-06-01
The acoustical cues for sound location are generated by spatial- and frequency-dependent filtering of propagating sound waves by the head and external ears. Although rats have been a common model system for anatomy, physiology, and psychophysics of localization, there have been few studies of the acoustical cues available to rats. Here, directional transfer functions (DTFs), the directional components of the head-related transfer functions, were measured in six adult rats. The cues to location were computed from the DTFs. In the frontal hemisphere, spectral notches were present for frequencies from approximately 16 to 30 kHz; in general, the frequency corresponding to the notch increased with increases in source elevation and in azimuth toward the ipsilateral ear. The maximum high-frequency envelope-based interaural time differences (ITDs) were 130 mus, whereas low-frequency (<3.5 kHz) fine-structure ITDs were 160 mus; both types of ITDs were larger than predicted from spherical head models. Interaural level differences (ILDs) strongly depended on location and frequency. Maximum ILDs were <10 dB for frequencies <8 kHz and were as large as 20-40 dB for frequencies >20 kHz. Removal of the pinna eliminated the spectral notches, reduced the acoustic gain and ILDs, altered the acoustical axis, and reduced the ITDs. PMID:18537381
NASA Astrophysics Data System (ADS)
Shi, De-Heng; Liu, Yu-Fang; Sun, Jin-Feng; Yang, Xiang-Dong; Zhu, Zun-Lue
2006-05-01
The reasonable dissociation limit of the A1Σ+ state 7LiH molecule is obtained. The accurate dissociation energy and the equilibrium geometry of this state are calculated using a symmetry-adapted-cluster configuration-interaction method in complete active space for the first time. The whole potential energy curve and the dipole moment function for the A1Σ+ state are calculated over a wide internuclear separation range from about 0.1 to 1.4 nm. The calculated equilibrium geometry and dissociation energy of this potential energy curve are of Re=0.2487 nm and De=1.064 eV, respectively. The unusual negative values of the anharmonicity constant and the vibration-rotational coupling constant are of ωeχe=-4.7158cm-1 and αe=-0.08649cm-1, respectively. The vertical excitation energy from the ground to the A1Σ+ state is calculated and the value is of 3.613 eV at 0.15875 nm (the equilibrium position of the ground state). The highly anomalous shape of this potential energy curve, which is exceptionally flat over a wide radial range around the equilibrium position, is discussed in detail. The harmonic frequency value of 502.47cm-1 about this state is approximately estimated. Careful comparison of the theoretical determinations with those obtained by previous theories about the A1Σ+ state dissociation energy clearly shows that the present calculations are much closer to the experiments than previous theories, thus represents an improvement.
Imagery-derived modulation transfer function and its applications for underwater imaging
NASA Astrophysics Data System (ADS)
Hou, Weilin; Weidemann, Alan D.; Gray, Deric J.; Fournier, Georges R.
2007-09-01
The main challenge working with underwater imagery results from both rapid decay of signals due to absorption, which leads to poor signal to noise returns, and the blurring caused by strong scattering by the water itself and constituents within, especially particulates. The modulation transfer function (MTF) of an optical system gives the detailed and precise information regarding the system behavior. Underwater imageries can be better restored with the knowledge of the system MTF or the point spread function (PSF), the Fourier transformed equivalent, extending the performance range as well as the information retrieval from underwater electro-optical system. This is critical in many civilian and military applications, including target and especially mine detection, search and rescue, and diver visibility. This effort utilizes test imageries obtained by the Laser Underwater Camera Imaging Enhancer (LUCIE) from Defense Research and Development Canada (DRDC), during an April-May 2006 trial experiment in Panama City, Florida. Imaging of a standard resolution chart with various spatial frequencies were taken underwater in a controlled optical environment, at varying distances. In-water optical properties during the experiment were measured, which included the absorption and attenuation coefficients, particle size distribution, and volume scattering function. Resulting images were preprocessed to enhance signal to noise ratio by averaging multiple frames, and to remove uneven illumination at target plane. The MTF of the medium was then derived from measurement of above imageries, subtracting the effect of the camera system. PSFs converted from the measured MTF were then used to restore the blurred imageries by different deconvolution methods. The effects of polarization from source to receiver on resulting MTFs were examined and we demonstrate that matching polarizations do enhance system transfer functions. This approach also shows promise in deriving medium optical
Tunable fluorescence in chromophore-functionalized nanodiamond induced by energy transfer
NASA Astrophysics Data System (ADS)
Maitra, Urmimala; Jain, Ankit; George, Subi J.; Rao, C. N. R.
2011-08-01
Hybrid materials comprising diamond nanoparticles (ND) and oligo(phenylenevinylenes) (OPVs) have been synthesized by the covalent linking of acid-functionalized ND and OPV-amine. Chromophore-functionalized ND particles with long alkyl and π-conjugated groups are readily dispersed in various organic solvents without any precipitation after several hours. A careful study of the properties of the hybrid materials revealed an aggregation-induced energy transfer from the blue fluorescent nanodiamonds to green emitting OPVs. At very low concentrations the hybrid emits in the blue region, but as the concentration is increased a gradual transition from blue to green emission occurs. Competitive processes such as aggregation-induced enhanced emission and self-absorption have been ruled out and a molecular picture of the phenomenon is proposed. This strategy can open a plethora of new avenues for fluorescent nanodiamonds in optoelectronics and light harvesting apart from bio-imaging.Hybrid materials comprising diamond nanoparticles (ND) and oligo(phenylenevinylenes) (OPVs) have been synthesized by the covalent linking of acid-functionalized ND and OPV-amine. Chromophore-functionalized ND particles with long alkyl and π-conjugated groups are readily dispersed in various organic solvents without any precipitation after several hours. A careful study of the properties of the hybrid materials revealed an aggregation-induced energy transfer from the blue fluorescent nanodiamonds to green emitting OPVs. At very low concentrations the hybrid emits in the blue region, but as the concentration is increased a gradual transition from blue to green emission occurs. Competitive processes such as aggregation-induced enhanced emission and self-absorption have been ruled out and a molecular picture of the phenomenon is proposed. This strategy can open a plethora of new avenues for fluorescent nanodiamonds in optoelectronics and light harvesting apart from bio-imaging. Electronic
Sterile inflammation after lymph node transfer improves lymphatic function and regeneration
Joseph, Walter J.; Aschen, Seth; Ghanta, Swapna; Cuzzone, Daniel; Albano, Nicholas; Gardenier, Jason; Savetsky, Ira; Torrisi, Jeremy; Mehrara, Babak J.
2014-01-01
Introduction Lymph node transplantation is a promising surgical technique for the treatment of lymphedema. However, while initial clinical results have been largely promising, inconsistent responses have been reported in some cases. While the cause of this inconsistency remains unknown, it is likely that impaired lymphangiogenesis and spontaneous regeneration of lymphatic vessels in the transplanted lymph nodes may be a contributing factor suggesting that development of novel techniques to augment lymphangiogenesis may be clinically useful. The aim of this study was therefore to determine if sterile inflammatory reactions can serve as a physiologic means of augmenting lymphangiogenesis in transplanted lymph nodes using a murine model. Methods We used our previously reported model of lymph node transfer to study the effect of sterile inflammation on lymphatic regeneration. Mice were divided into 3 groups: Group 1 animals served as controls and underwent lymphadenectomy followed by immediate lymph node transplantation without inflammation. Group 2 animals (inflammation before transfer) were transplanted with lymph nodes harvested from donor animals in which a sterile inflammatory reaction was induced in the ipsilateral donor limb using complete Freund’s adjuvant and ovalbumin (CFA/OVA). Group 3 animals (inflammation after transfer) were transplanted with lymph nodes and then inflammation was induced in the ipsilateral limb using CFA/OVA. Lymphatic function, lymphangiogenesis, and lymph node histology were examined 28 days after transplant and compared with normal lymph node. Results Animals that had sterile inflammation after transplantation (group 3) had significantly improved lymphatic function (>2 fold increase) as assessed by lymphoscintigraphy, increased peri-nodal lymphangiogenesis, and functional lymphatics as compared with no-inflammation or inflammation before transplant groups (p<0.01). In addition, inflammation after transplantation was associated a more
A general transfer-function approach to noise filtering in open-loop quantum control
NASA Astrophysics Data System (ADS)
Viola, Lorenza
2015-03-01
Hamiltonian engineering via unitary open-loop quantum control provides a versatile and experimentally validated framework for manipulating a broad class of non-Markovian open quantum systems of interest, with applications ranging from dynamical decoupling and dynamically corrected quantum gates, to noise spectroscopy and quantum simulation. In this context, transfer-function techniques directly motivated by control engineering have proved invaluable for obtaining a transparent picture of the controlled dynamics in the frequency domain and for quantitatively analyzing performance. In this talk, I will show how to identify a computationally tractable set of ``fundamental filter functions,'' out of which arbitrary filter functions may be assembled up to arbitrary high order in principle. Besides avoiding the infinite recursive hierarchy of filter functions that arises in general control scenarios, this fundamental set suffices to characterize the error suppression capabilities of the control protocol in both the time and frequency domain. I will show, in particular, how the resulting notion of ``filtering order'' reveals conceptually distinct, albeit complementary, features of the controlled dynamics as compared to the ``cancellation order,'' traditionally defined in the Magnus sense. Implications for current quantum control experiments will be discussed. Work supported by the U.S. Army Research Office under Contract No. W911NF-14-1-0682.
NASA Astrophysics Data System (ADS)
Pittelkau, Mark E.; McKinley, William G.
2016-06-01
We define the displacement, smear, and jitter components of image motion and derive the two-dimensional statistical image motion optical transfer function (OTF) corresponding to each component. These statistical OTFs are parameterized by means and covariances, which are computed most conveniently from a weighted power spectrum of the line-of-sight motion. Another feature of these results is the realization that all temporal and spatial frequencies contribute to each statistical OTF and that one can determine the frequencies that contribute most significantly to each OTF. Additionally, optical system design is typically based upon the properties of an individual image. In a comprehensive optical system design, the statistical properties of an ensemble of images should also be considered. For individual images subject to a constant but possibly unknown smear length, the OTF is a sinc function. This is called a deterministic smear OTF because it does not describe the smear statistically. The statistical smear OTF describes the average smear OTF for an ensemble of images.
Empirical transfer functions for stations in the Central California seismological network
Bakun, W.H.; Dratler, Jay
1976-01-01
A sequence of calibration signals composed of a station identification code, a transient from the release of the seismometer mass at rest from a known displacement from the equilibrium position, and a transient from a known step in voltage to the amplifier input are generated by the automatic daily calibration system (ADCS) now operational in the U.S. Geological Survey central California seismographic network. Documentation of a sequence of interactive programs to compute, from the calibration data, the complex transfer functions for the seismographic system (ground motion through digitizer) the electronics (amplifier through digitizer), and the seismometer alone are presented. The analysis utilizes the Fourier transform technique originally suggested by Espinosa et al (1962). Section I is a general description of seismographic calibration. Section II contrasts the 'Fourier transform' and the 'least-squares' techniques for analyzing transient calibration signals. Theoretical consideration for the Fourier transform technique used here are described in Section III. Section IV is a detailed description of the sequence of calibration signals generated by the ADCS. Section V is a brief 'cookbook description' of the calibration programs; Section VI contains a detailed sample program execution. Section VII suggests the uses of the resultant empirical transfer functions. Supplemental interactive programs by which smooth response functions, suitable for reducing seismic data to ground motion, are also documented in Section VII. Appendices A and B contain complete listings of the Fortran source Codes while Appendix C is an update containing preliminary results obtained from an analysis of some of the calibration signals from stations in the seismographic network near Oroville, California.
Bhattacharyya, Sanchari; Manhart, Michael; Choi, Jeong-Mo; Mu, Wanmeng; Zhou, Jingwen; Shakhnovich, Eugene I.
2015-01-01
Horizontal gene transfer (HGT) plays a central role in bacterial evolution, yet the molecular and cellular constraints on functional integration of the foreign genes are poorly understood. Here we performed inter-species replacement of the chromosomal folA gene, encoding an essential metabolic enzyme dihydrofolate reductase (DHFR), with orthologs from 35 other mesophilic bacteria. The orthologous inter-species replacements caused a marked drop (in the range 10–90%) in bacterial growth rate despite the fact that most orthologous DHFRs are as stable as E.coli DHFR at 37°C and are more catalytically active than E. coli DHFR. Although phylogenetic distance between E. coli and orthologous DHFRs as well as their individual molecular properties correlate poorly with growth rates, the product of the intracellular DHFR abundance and catalytic activity (k cat/KM), correlates strongly with growth rates, indicating that the drop in DHFR abundance constitutes the major fitness barrier to HGT. Serial propagation of the orthologous strains for ~600 generations dramatically improved growth rates by largely alleviating the fitness barriers. Whole genome sequencing and global proteome quantification revealed that the evolved strains with the largest fitness improvements have accumulated mutations that inactivated the ATP-dependent Lon protease, causing an increase in the intracellular DHFR abundance. In one case DHFR abundance increased further due to mutations accumulated in folA promoter, but only after the lon inactivating mutations were fixed in the population. Thus, by apparently distinguishing between self and non-self proteins, protein homeostasis imposes an immediate and global barrier to the functional integration of foreign genes by decreasing the intracellular abundance of their products. Once this barrier is alleviated, more fine-tuned evolution occurs to adjust the function/expression of the transferred proteins to the constraints imposed by the intracellular
Analytical solution of beam spread function for ocean light radiative transfer.
Xu, Zao; Yue, Dick K P
2015-07-13
We develop a new method to analytically obtain the beam spread function (BSF) for light radiative transfer in oceanic environments. The BSF, which is defined as the lateral distribution of the (scalar) irradiance with increasing depth in response to a uni-directional beam emanating from a point source in an infinite ocean, must in general be obtained by solving the three-dimensional (3D) radiative transfer equation (RTE). By taking advantage of the highly forward-peaked scattering property of the ocean particles, we assume, for a narrow beam source, the dependence of radiance on polar angle and azimuthal angle is deliberately separated; only single scattering takes place in the azimuthal direction while multiple scattering still occurs in the polar direction. This assumption enables us to reduce the five-variable 3D RTE to a three-variable two-dimensional (2D) RTE. With this simplification, we apply Fourier spectral method to both spatial and angular variables so that we are able to analytically solve the 2D RTE and obtain the 2D BSF accordingly. Using the relations between 2D and 3D solutions acquired during the process of simplification, we are able to obtain the 3D BSF in explicit form. The 2D and 3D analytical solutions are validated by comparing with Monte Carlo radiative transfer simulations. The 2D analytical BSF agrees excellently with the Monte Carlo result. Despite assumptions of axial symmetry and spike-like azimuthal profile of the radiance in deriving the 3D BSF, the comparisons to numerical simulations are very satisfactory especially for limited optical depths (< O(5)) for single scattering albedo values typical in the ocean. The explicit form of the analytical BSF and the significant gain in computational efficiency (several orders higher) relative to RTE simulations make many forward and inverse problems in ocean optics practical for routine applications. PMID:26191856
NASA Astrophysics Data System (ADS)
Yashchuk, V. M.; Kudrya, V. Yu.; Dubey, I. Ya.; Fedorovich, R. D.; Suga, H.; Savchenko, I. O.; Golovach, G. P.
2007-06-01
The results of the design, synthesis and investigations of the compounds (possessing predicted unidirect excitations conductivity) containing several π-electron systems (including nucleotides - the short DNA-fragments) are reported. The predicted processes of unidirect triplet excitations transfer in all investigated compounds were proved. The nature of electronic excitations traps in the compounds investigated is discussed. For the molecular systems composed from the DNA-fragments spectral investigations show the adenosine-thymidine-sequences are such traps in these compounds as well as the DNA [1]. The energy levels lowering existence from chromophore to chromophore along the molecular system gives the ground to predict not only unidirect neutral excitation transfer but unidirect charge carrier current. Really the "diode" I(U) characteristic for metal-organic system of gold islands connected by π-electron-containing molecules was observed. This gives the possibility to propose these compounds to be used for nanoelectronic devices design. Computer simulations of electronic excitations passing through the oligomer functional macromolecule taking into account reverse exciton currents show such type macromolecules are perspective for applying in nanophotonics.
Ichinose, Hirofumi; Michizoe, Junji; Maruyama, Tatsuo; Kamiya, Noriho; Goto, Masahiro
2004-06-22
Enzyme-based electron-transfer reactions involved in the cytochrome P450 monooxygenase system were investigated in nanostructural reverse micelles. A bacterial flavoprotein, putidaredoxin reductase (PdR), was activated and shown to be capable of catalyzing the electron transport from NADH to electron-carrier proteins such as cytochrome b5 (tCyt-b5) and putidaredoxin (Pdx) in reverse micelles. Ferric tCyt-b5 in reverse micelles was effectively converted to its ferrous form by the exogenous addition of separately prepared reverse micellar solution harboring PdR and NADH. The fact that direct interactions of macromolecular proteins should be possible in the reverse micellar system encouraged us to functionalize a multicomponent monooxygenase system composed of the bacterial cytochrome P450cam (P450cam), putidaredoxin (Pdx), and PdR in reverse micelles. The successful camphor hydroxylation reaction catalyzed by P450cam was significantly dependent on the coexistence of Pdx, PdR, and NADH but not H2O2, suggesting that the oxygen-transfer reactions proceeded via a "monooxygenation" mechanism. This is the first report of a multicomponent cytochrome P450 system exhibiting enzymatic activity in organic media. PMID:15986701
Determination of the modulation transfer function for a time-gated fluorescence imaging system.
Gundy, Sarah; Van der Putten, Wil; Shearer, Andy; Buckton, Daniel; Ryder, Alan G
2004-01-01
The use of fluorescence for cancer detection is currently under investigation. Presently, steady-state fluorescence detection methods are in use, but have limitations due to poor contrast between the fluorescence of the tumor and background autofluorescence. Improved contrast can be obtained with time-resolved techniques because of the differing lifetimes between autofluorescence and exogenous photosensitizers that selectively accumulate within tumor tissue. An imaging system is constructed using a fast-gated (200-ps) charge-coupled device (CCD) camera and a pulsed 635-nm laser diode. To characterize the ability of the system to transfer object contrast to an image, the modulation transfer function (MTF) of the system is acquired by employing an extended knife-edge technique. A knife-edge target is assembled by drilling a rectangular well into a block of polymethyl methacrylate (PMMA). The imaging system records images of the photosensitizer, chloroaluminum phthalocyanine tetrasulfonate (AlPcTS), within the well. AlPcTS was chosen to test the system because of its strong absorption of 635-nm, high fluorescence yield, and relatively long fluorescence lifetime (approximately 7.5 ns). The results show that the system is capable of resolving 10(-4) M AlPcTS fluorescence as small as 1 mm. The findings of this study contribute to the development of a time-gated imaging system using fluorescence lifetimes. PMID:15568941
Proton transfer along water bridges in biological systems with density-functional tight-binding
NASA Astrophysics Data System (ADS)
Reiss, Krystle; Wise, Abigail; Mazzuca, James
2015-03-01
When examining the dynamics of charge transfer in high dimensional enzymatic systems, the cost of quantum mechanical treatment of electrons increases exponentially with the size of the system. As a semi-empirical method, density-functional tight-binding aids in shortening these calculation times, but can be inaccurate in the regime where bonds are being formed and broken. To address these inaccuracies with respect to proton transfer in an enzymatic system, DFTB is being used to calculate small model systems containing only a single amino acid residue donor, represented by an imidazole molecule, and a water acceptor. When DFTB calculations are compared to B3LYP geometry calculations of the donor molecule, we observe a bond angle error on the order of 1.2 degrees and a bond length error on the order of 0.011 Å. As we move forward with small donor-acceptor systems, comparisons between DFTB and B3LYP energy profiles will provide a better clue as to what extent improvements need to be made. To improve the accuracy of the DFTB calculations, the internuclear repulsion term may be altered. This would result in energy profiles that closely resemble those produced by higher-level theory. Alma College Provost's Office.
NASA Astrophysics Data System (ADS)
Kwak, Giseop; Okada, Chisato; Fujiki, Michiya; Takeda, Hiroaki; Nishida, Takashi; Shiosaki, Tadashi
2008-03-01
In this paper, we describe the photophysical properties and new functions of 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran (DCM) and its derivative, 2-methyl-6-[2-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-9-yl)-ethenyl]-4H-pyran-4-ylidene)propane dinitrile (DCM2) in various polymer matrices, with respect to intramolecular charge transfer (ICT). The maximum fluorescence wavelengths of DCM and DCM2 shifted to red with an increase in the dielectric constant of the polymer matrix. The fluorescence lifetime shortened according to the matrix polarity. When a polymer with a dielectric constant varying according to its crystalline structure, poly(vinylidenefluoride-co-trifluoroethylene) (PVdF-co-TrFE), was used as a matrix, we were able to thermally tune the fluorescence wavelength as well as the fluorescence intensity of DCM2. The locked molecular structure of DCM2 was very effective for maintaining the charge transfer character during thermal stimulation.
NASA Technical Reports Server (NTRS)
Ko, William L.; Fleischer, Van Tran
2015-01-01
Variable-Domain Displacement Transfer Functions were formulated for shape predictions of complex wing structures, for which surface strain-sensing stations must be properly distributed to avoid jointed junctures, and must be increased in the high strain gradient region. Each embedded beam (depth-wise cross section of structure along a surface strain-sensing line) was discretized into small variable domains. Thus, the surface strain distribution can be described with a piecewise linear or a piecewise nonlinear function. Through discretization, the embedded beam curvature equation can be piece-wisely integrated to obtain the Variable-Domain Displacement Transfer Functions (for each embedded beam), which are expressed in terms of geometrical parameters of the embedded beam and the surface strains along the strain-sensing line. By inputting the surface strain data into the Displacement Transfer Functions, slopes and deflections along each embedded beam can be calculated for mapping out overall structural deformed shapes. A long tapered cantilever tubular beam was chosen for shape prediction analysis. The input surface strains were analytically generated from finite-element analysis. The shape prediction accuracies of the Variable- Domain Displacement Transfer Functions were then determined in light of the finite-element generated slopes and deflections, and were fofound to be comparable to the accuracies of the constant-domain Displacement Transfer Functions
Experimental measurement of modulation transfer function of a retina-like sensor
NASA Astrophysics Data System (ADS)
Wang, Fan; Cao, Fengmei; Bai, Tingzhu; Cao, Nan; Liu, Changju; Deng, Guangping
2014-11-01
The retina-like sensor is a kind of anthropomorphic visual sensor. It plays an important role in both biological and machine vision due to its advantages of high resolution in the fovea, a wide field-of-view, and minimum pixel count. The space-variant property of the sensor makes it difficult to directly measure its modulation transfer function (MTF). The MTF of a retina-like sensor is measured with the bar-target pattern method. According to the pixel arrangement, the sensor is divided into rings and the MTF of each ring is measured using spoke targets with different periods. Comparison between the measured MTF and the theoretical MTF of the sensor showed that they coincide. The differences between them are also analyzed and discussed. The measured MTF helps to analyze the performance of an imaging system containing a retina-like sensor.
Han, Jiefei; Yang, Kecheng; Xia, Min; Sun, Liying; Cheng, Zao; Liu, Hao; Ye, Junwei
2015-04-10
Active polarization imaging technology is a convenient and promising method for imaging in a scattering medium such as fog and turbid water. However, few studies have investigated the influence of polarization on the resolution in underwater imaging. This paper reports on the effects of polarization detection on the resolution of underwater imaging by using active polarization imaging technology. An experimental system is designed to determine the influence under various polarization and water conditions. The modulation transfer function is introduced to estimate the resolution variations at different spatial frequencies. Results show that orthogonal detection supplies the best resolution compared with other polarization directions in the turbid water. The performance of the circular polarization method is better than the linear process. However, if the light propagates under low scattering conditions, such as imaging in clean water or at small optical thickness, the resolution enhancement is not sensitive to the polarization angles. PMID:25967316
Measurements of Modulation Transfer Function and Spatial Noise in Infrared Ccd's
NASA Astrophysics Data System (ADS)
Boreman, Glenn David
This dissertation deals with the measurement of Modulation Transfer Function (MTF) and spatial noise in infrared CCD's. A new method for the measurement of MTF is presented, which uses the phenomenon of laser speckle. The instrument constructed has the advantages that it does not require components of high optical or mechanical quality, and it does not require precise alignment. There is only one moving part in the system. The results of this method are compared with results obtained from an interferometric technique and from an impulse response technique, and found to be in close agreement. The characterization of spatially -dependent noise is pursued via the formalism of Detective Quantum Efficiency and also via a two dimensional generalization of the classical representation for information capacity. Suggestions for improving the performance of the array as a signal processor are drawn from these considerations. Test results are presented for a 64 by 32 element infrared CCD of Schottky barrier construction.
NASA Astrophysics Data System (ADS)
Fernández-Oliveras, Alicia; Pozo, Antonio M.; Rubiño, Manuel
2013-01-01
Charge-coupled device (CCD) and complementary metal-oxide semiconductor (CMOS) matrices offer excellent features in imaging systems. For assessing the suitability of each technology according to the application, the complete characterization of the detector arrays becomes necessary. A system is optically characterized by the modulation transfer function (MTF). We have comparatively studied the results provided by the speckle method for detectors of two types: CCD and CMOS. To do so, we first analysed the precision in determining the MTF of the CCD using two apertures at the exit port of an integrating sphere: a single and a double-slit. For the single-slit, we propose a new procedure of fitting the experimental data which overcomes the drawbacks of the conventional procedure. Since it offered lower uncertainty and better reproducibility, the single-slit was used for the study with the CMOS detector. Significant differences were found between the MTF of the CCD and the CMOS detectors.
Pozo, A M; Ferrero, A; Rubiño, M; Campos, J; Pons, A
2006-06-26
We present and evaluate two corrections applicable in determining the modulation transfer function (MTF) of a charge-coupled device (CCD) by the speckle method that minimize its uncertainty: one for the low frequency region and another for the high frequency region. The correction at the low-spatial-frequency region enables attenuation of the high power-spectral-density values that arise from the field and CCD response non-uniformities. In the high-spatial-frequency region the results show that the distance between the CCD and the aperture is critical and significantly influences the MTF; a variation of 1 mm in the distance can cause a root-mean-square error in the MTF higher than 10%. We propose a simple correction that minimizes the experimental error committed in positioning the CCD and that diminishes the error to 0.43%. PMID:19516762
NASA Astrophysics Data System (ADS)
Pozo, A. M.; Ferrero, A.; Rubiño, M.; Campos, J.; Pons, A.
2006-06-01
We present and evaluate two corrections applicable in determining the modulation transfer function (MTF) of a charge-coupled device (CCD) by the speckle method that minimize its uncertainty: one for the low frequency region and another for the high frequency region. The correction at the low-spatial-frequency region enables attenuation of the high power-spectral-density values that arise from the field and CCD response non-uniformities. In the high-spatial-frequency region the results show that the distance between the CCD and the aperture is critical and significantly influences the MTF; a variation of 1 mm in the distance can cause a root-mean-square error in the MTF higher than 10%. We propose a simple correction that minimizes the experimental error committed in positioning the CCD and that diminishes the error to 0.43%.
NASA Astrophysics Data System (ADS)
Pinkie, Benjamin; Wichman, Adam R.; Bellotti, Enrico
2015-09-01
Finite-difference time-domain and finite element method simulations are used to evaluate two-dimensional spot-scan profiles of p-on- n double-layer planar heterostructure (DLPH) detector arrays with abrupt p-type diffusions. The modulation transfer function (MTF) is calculated from the spot-scan profiles. An asymmetric dark and photo current collection mechanism is identified and explained as a result of electric field bunching through the corners of polygonal diffusions in DLPH arrays. The MTF consequences of the asymmetric collection are studied for triangular, square, and hexagonal diffusions in square and hexagonal arrays. We show that the placement and shape of the diffusion relative to the pixel can modify the MTF by several percent. The magnitude of the effect is largest for diffusions with fewer degrees of rotational symmetry.
NASA Astrophysics Data System (ADS)
Nakaya, Y.; Kawata, Y.; Niki, N.; Ohmatsu, H.; Moriyama, N.
2012-03-01
The recent CT systems yield high spatial resolution in all directions of volumetric images in clinical routine. The quantitative characterization of the performance of CT systems is important for comparing the effects of different scan and reconstruction parameters, for comparing between different CT systems, and for evaluating the accuracy of size and density measurements of fine details in CT images. This paper presents a method to determine the modulation transfer function (MTF) in the scan plane obtained by CT system from profiles of human anatomical structures such as blood vessel measured by clinical measurement conditions without magnified reconstruction. MTF estimations are performed for cylindrical tube phantoms with three different diameters (1 mm, 2 mm, and 3 mm) injected by solution of contrast material and human blood vessels measured by the clinical measurement conditions. We demonstrate the potential usefulness of the method for estimating the MTF from blood vessel profiles measured in CT systems.
Characterization of detector modulation-transfer function with noise, edge, and holographic methods.
McLeod, Robert A; Malac, Marek
2013-06-01
We developed a new method for characterization of detector performance used in the transmission electron microscope (TEM) based on the measured contrast of holographic fringes. The new method changes spatial frequency of the measured holographic fringes, generated by an electrostatic biprism and Schottky or cold field-emission gun, to sample the modulation-transfer function (MTF) of the detector. The MTF of a Gatan Ultrascan™ 1000 charged-coupled detector (CCD) is evaluated using the new method and the results are compared to the established noise and slanted-edge method results. Requirements for accuracy of the edge and noise MTF methods are discussed. We consider issues surrounding incomplete read-out and how it affects the gain reference normalization of the detector. We evaluate how the MTF affects optimization of experimental parameters in the TEM. PMID:23603855
NASA Astrophysics Data System (ADS)
Zhang, Xujie; Kashti, Tamar; Kella, Dror; Frank, Tal; Shaked, Doron; Ulichney, Robert; Fischer, Mani; Allebach, Jan P.
2012-01-01
The modulation transfer function (MTF) is a fundamental tool for assessing the performance of imaging systems. It has been applied to a range of capture and output devices, including printers and even the media itself. In this paper, we consider the problem of measuring the MTF of image capture devices. We analyze the factors that limit the MTF of a capture device. Then, we examine three different approaches to this task based, respectively, on a slant-edge target, a sinewave target, and a grill pattern. We review the mathematical relationship between the three different methods, and discuss their comparative advantages and disadvantages. Finally, we present experimental results for MTF measurement with a number of different commercially available image capture devices that are specifically designed for capture of 2D reflection or transmission copy. These include camera-based systems, flat-bed scanners, and a drum scanner.
Katz, M; Citek, K; Arditi, A
1988-03-01
An instrument using an electro-optical Fourier method for measuring the modulation transfer function (MTF) of low power telescopes and telemicroscopes is described. Because these devices are afocal, or nearly so, relay optics are needed to form real images at the detection section of the apparatus. The system is capable of measuring the MTF in monochromatic and white light, at any target azimuth, across the field of view, and through focus. The target system contains 14 square-wave gratings with spatial frequencies that range from 2.5 to 156 cpd. Images of these gratings are scanned across a slit. The output data are fed to a first-order recursive digital Butterworth bandpass filter for MTF analysis. The apparatus is diffraction limited at f/31.4. Therefore, it negligibly affects the measurement of the MTF of telescopes and telemicroscopes tested with exit pupils of up to 6.4 mm. PMID:3364527
Application of modulation transfer function in high-resolution image fusion
NASA Astrophysics Data System (ADS)
Zhang, Xiaoping; Jia, Yonghong; Chen, Xiaoyan; Pan, Delu; Chen, Jianyu; Hao, Zengzhou
2011-11-01
Modulation transfer function (MTF) is applied to the high frequency modulation fusion in this paper. Firstly, MTFs are calculated using the edge method, and 2-dimension MTF-filters are properly designed. Secondly, MTF-filters are used for degrading original high resolusion images. High frequency modulation fusion parameters are then obtained under the minimum mean square error criterion. The results show that fusion images derived from the improved high frequency modulation based on MTF method have spatial resolution close to non-degraded pan images. Compared with fusion methods of weighted high-pass filtering (w-HPF), MTF general image fusion framework (MTF-GIF), the improved method performs well in terms of preservation of spectral information and spatial resolution.
Poulíčková, Aloisie; Hájková, Petra; Kintrová, Kateřina; Bat'ková, Romana; Czudková, Markéta; Hájek, Michal
2013-08-01
Central European mountain bogs, among the most valuable and threatened of habitats, were exposed to intensive human impact during the 20th century. We reconstructed the subrecent water chemistry and water-table depths using diatom based transfer functions calibrated from modern sampling. Herbarium Sphagnum specimens collected during the period 1918-1998 were used as a source of historic diatom samples. We classified samples into hummocks and hollows according to the identity of dominant Sphagnum species, to reduce bias caused by uneven sampling of particular microhabitats. Our results provide clear evidence for bog pollution by grazing during the period 1918-1947 and by undocumented aerial liming in the early 90-ies. We advocate use of herbarized epibryon as a source of information on subrecent conditions in recently polluted mires. PMID:23688732
NASA Astrophysics Data System (ADS)
Qiu, Q.; Fang, Z. P.; Wan, H. C.; Zheng, L.
2013-07-01
Based on the Donnell assumptions and linear visco-elastic theory, the constitutive equations of the cylindrical shell with multilayer Passive Constrained Layer Damping (PCLD) treatments are described. The motion equations and boundary conditions are derived by Hamilton principle. After trigonometric series expansion and Laplace transform, the state vector is introduced and the dynamic equations in state space are established. The transfer function method is used to solve the state equation. The dynamic performance including the natural frequency, the loss factor and the frequency response of clamped-clamped multi-layer PCLD cylindrical shell is obtained. The results show that multi-layer PCLD cylindrical shell is more effective than the traditional three-layer PCLD cylindrical shell in suppressing vibration and noise if the same amount of material is applied. It demonstrates a potential application of multi-layer PCLD treatments in many critical structures such as cabins of aircrafts, hulls of submarines and bodies of rockets and missiles.
NASA Astrophysics Data System (ADS)
Totaro, N.; Guyader, J. L.
2012-06-01
Given the need to decrease energy consumption in the automobile industry, vehicle weight has become an important issue. Regarding acoustic comfort, the weight of noise reduction devices must be minimized inside vehicle compartments. Consequently, these devices, for example those using poro-elastic materials, must be designed carefully to maximize their influence on noise reduction. The present paper describes a method developed to obtain an efficient positioning of a given surface (or mass) of absorbing material characterized by its surface impedance. This technique is based on the Patch Transfer Function method used to couple complex vibro-acoustic sub-domains and which has been successfully applied in the European ViSPeR and Silence projects. First, a numerical analysis of the possibilities of this method is performed on a non-rectangular cavity with rigid walls after which an experimental validation of this numerical analysis is performed to evaluate the accuracy of the method under real conditions.
Directional Hearing and Head-Related Transfer Function in Odontocete Cetaceans.
Krysl, Petr; Cranford, Ted W
2016-01-01
The head-related transfer function (HRTF) is an important descriptor of spatial sound field reception by the listener. In this study, we computed the HRTF of the common dolphin Delphinus delphis. The received sound pressure level at various locations within the acoustic fats of the internal pinna near the surface of the tympanoperiotic complex (TPC) was calculated for planar incident waves directed toward the animal. The relative amplitude of the received pressure versus the incident pressure was the representation of the HRTF from the point of view of the animal. It is of interest that (1) different locations on the surface of the TPC resulted in different HRTFs, (2) the HRTFs for the left and right ears were slightly asymmetric, and (3) the locations of the peaks of the HRTF depended on the frequency of the incident wave. PMID:26611007
Head-related transfer function interpolation in azimuth, elevation, and distance.
Gamper, Hannes
2013-12-01
Although distance-dependent head-related transfer function (HRTF) databases provide interesting possibilities, e.g., for rendering virtual sounds in the near-field, there is a lack of algorithms and tools to make use of them. Here, a framework is proposed for interpolating HRTF measurements in 3-D (i.e., azimuth, elevation, and distance) using tetrahedral interpolation with barycentric weights. For interpolation, a tetrahedral mesh is generated via Delaunay triangulation and searched via an adjacency walk, making the framework robust with respect to irregularly positioned HRTF measurements and computationally efficient. An objective evaluation of the proposed framework indicates good accordance between measured and interpolated near-field HRTFs. PMID:25669302
Numerical Simulation of the Modulation Transfer Function in HgCdTe Detector Arrays
NASA Astrophysics Data System (ADS)
Pinkie, Benjamin; Bellotti, Enrico
2014-08-01
In this work, we develop a method for simulating the modulation transfer function (MTF) of infrared detector arrays, which is based on numerical evaluation of the detector physics. The finite-difference time-domain and finite element methods are used to solve the electromagnetic and electrical equations for the device, respectively. We show how the total MTF can be deconvolved to examine the effects of specific physical processes. We introduce the MTF area difference and use it to quantify the effectiveness of several crosstalk mitigation techniques in improving the system MTF. We then apply our simulation methods to two-thirds generation mercury cadmium telluride (HgCdTe) detector architectures. The methodology is general, can be implemented with commercially available software, has experimentally realizable analogs, and is extendable to other material systems and device designs.