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Sample records for acero fundido refractario

  1. 76 FR 67253 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ACERO AZUL; Invitation for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Maritime Administration Requested Administrative Waiver of the Coastwise Trade Laws: Vessel ACERO AZUL... the vessel ACERO AZUL is: INTENDED COMMERCIAL USE OF VESSEL: ``Passenger for hire.'' GEOGRAPHIC...

  2. "Estudio tribologico de aceros para moldes. Aplicacion al moldeo por inyeccion de polibutilentereftalato reforzado con fibra de vidrio"

    NASA Astrophysics Data System (ADS)

    Martinez Mateo, Isidoro Jose

    fabricacion del molde, tienen una gran influencia sobre su comportamiento en servicio a lo largo de la vida util del molde. En la primera parte del presente estudio, a partir de ensayos punzon sobre disco, se ha determinado la relacion entre la resistencia al desgaste y la dureza de aceros para moldes obtenidos a partir de bloques de gran espesor, estudiando los principales mecanismos de desgaste que tienen lugar. A continuacion, con el fin de determinar el dano superficial que sufren los aceros para moldes en condiciones reales de inyeccion, se han estudiado distintos tipos de aceros utilizados comercialmente en moldes de inyeccion de polimeros y materiales compuestos, seleccionando las condiciones de operacion para determinar la variacion de la rugosidad superficial del acero en funcion del material inyectado, del numero de operaciones sucesivas de inyeccion y de la orientacion del flujo de inyeccion, mediante tecnicas de perfilometria optica y microscopia electronica de barrido. Ademas del dano superficial sufrido por el acero con el numero de piezas inyectadas, tambien se ha determinado la evolucion de la rugosidad superficial de los materiales inyectados, polibutilentereftalato (PBT) puro y materiales compuestos derivados de PBT por adicion de un 20 o un 50% en peso de fibra de vidrio. En el caso de las piezas inyectadas, se ha caracterizado su microestructura en funcion del flujo de inyeccion y de la densidad de fibra, se han determinado sus propiedades termicas y dinamico-mecanicas, asi como la variacion de la rugosidad superficial de las piezas inyectadas con el numero de operaciones de inyeccion y con la geometria de las distintas secciones de las piezas. Finalmente, se ha evaluado la resistencia a la abrasion de PBT reforzado con un 50% de fibra, en funcion del numero de piezas inyectadas y de la direccion de rayado con respecto a la orientacion del flujo de inyeccion.

  3. VizieR Online Data Catalog: The first Fermi LAT SNR catalog (1SC) (Acero+, 2016)

    NASA Astrophysics Data System (ADS)

    Acero, F.; Ackermann, M.; Ajello, M.; Baldini, L.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Bellazzini, R.; Bissaldi, E.; Blandford, R. D.; Bloom, E. D.; Bonino, R.; Bottacini, E.; Brandt, T. J.; Bregeon, J.; Bruel, P.; Buehler, R.; Buson, S.; Caliandro, G. A.; Cameron, R. A.; Caputo, R.; Caragiulo, M.; Caraveo, P. A.; Casandjian, J. M.; Cavazzuti, E.; Cecchi, C.; Chekhtman, A.; Chiang, J.; Chiaro, G.; Ciprini, S.; Claus, R.; Cohen, J. M.; Cohen-Tanugi, J.; Cominsky, L. R.; Condon, B.; Conrad, J.; Cutini, S.; D'Ammando, F.; de Angelis, A.; de Palma, F.; Desiante, R.; Digel, S. W.; di Venere, L.; Drell, P. S.; Drlica-Wagner, A.; Favuzzi, C.; Ferrara, E. C.; Franckowiak, A.; Fukazawa, Y.; Funk, S.; Fusco, P.; Gargano, F.; Gasparrini, D.; Giglietto, N.; Giommi, P.; Giordano, F.; Giroletti, M.; Glanzman, T.; Godfrey, G.; Gomez-Vargas, G. A.; Grenier, I. A.; Grondin, M.-H.; Guillemot, L.; Guiriec, S.; Gustafsson, M.; Hadasch, D.; Harding, A. K.; Hayashida, M.; Hays, E.; Hewitt, J. W.; Hill, A. B.; Horan, D.; Hou, X.; Iafrate, G.; Jogler, T.; Johannesson, G.; Johnson!, A. S.; Ka, Mae T.; Katagiri, H.; Kataoka, J.; Katsuta, J.; Kerr, M.; Knodlseder, J.; Kocevski, D.; Kuss, M.; Laffon, H.; Lande, J.; Larsson, S.; Latronico, L.; Lemoine-Goumard, M.; Li, J.; Li, L.; Longo, F.; Loparco, F.; Lovellette, M. N.; Lubrano, P.; Magill, J.; Maldera, S.; Marelli, M.; Mayer, M.; Mazziotta, M. N.; Michelson, P. F.; Mitthumsiri, W.; Mizuno, T.; Moiseev, A. A.; Monzani, M. E.; Moretti, E.; Morselli, A.; Moskalenko, I. V.; Murgia, S.; Nemmen, R.; Nuss, E.; Ohsugi, T.; Omodei, N.; Orienti, M.; Orlando, E.; Ormes, J. F.; Paneque, D.; Perkins, J. S.; Pesce-Rollins, M.; Petrosian, V.; Piron, F.; Pivato, G.; Porter, T. A.; Raino, S.; Rando, R.; Razzano, M.; Razzaque, S.; Reimer, A.; Reimer, O.; Renaud, M.; Reposeur, T.; Rousseau, R.; Saz Parkinson, P. M.; Schmid, J.; Schulz, A.; Sgro, C.; Siskind, E. J.; Spada, F.; Spandre, G.; Spinelli, P.; Strong, A. W.; Suson, D. J.; Tajima, H.; Takahashi, H.; Tanaka, T.; Thayer, J. B.; Thompson, D. J.; Tibaldo, L.; Tibolla, O.; Torres, D. F.; Tosti, G.; Troja, E.; Uchiyama, Y.; Vianello, G.; Wells, B.; Wood, K. S.; Wood, M.; Yassine, M.; Den Hartog P. R.; Zimmer, S.

    2016-06-01

    We have systematically characterized the Fermi/LAT 1-100GeV emission from 36 months (from 2008 August 4 to 2011 August 4) in 279 regions containing known radio SNRs, identifying sources emitting in the regions and then determining the likelihood that the source nearest the SNR is associated with it. We found 102 candidates, 30 of which have sufficient spatial overlap and significance with the alternative IEMs to suggest they are the GeV counterparts to their corresponding radio SNRs and an additional 14 candidates which may also be related to the SNRs. (3 data files).

  4. VizieR Online Data Catalog: Fermi LAT third source catalog (3FGL) (Acero+, 2015)

    NASA Astrophysics Data System (ADS)

    Acero, F.; Ackermann, M.; Ajello, M.; Albert, A.; Atwood, W. B.; Axelsson, M.; Baldini, L.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Belfiore, A.; Bellazzini, R.; Bissaldi, E.; Blandford, R. D.; Bloom, E. D.; Bogart, J. R.; Bonino, R.; Bottacini, E.; Bregeon, J.; Britto, R. J.; Bruel, P.; Buehler, R.; Burnett, T. H.; Buson, S.; Caliandro, G. A.; Cameron, R. A.; Caputo, R.; Caragiulo, M.; Caraveo, P. A.; Casandjian, J. M.; Cavazzuti, E.; Charles, E.; Chaves, R. C. G.; Chekhtman, A.; Cheung, C. C.; Chiang, J.; Chiaro, G.; Ciprini, S.; Claus, R.; Cohen-Tanugi, J.; Cominsky, L. R.; Conrad, J.; Cutini, S.; D'Ammando, F.; de Angelis, A.; Deklotz, M.; de Palma, F.; Desiante, R.; Digel, S. W.; di Venere, L.; Drell, P. S.; Dubois, R.; Dumora, D.; Favuzzi, C.; Fegan, S. J.; Ferrara, E. C.; Finke, J.; Franckowiak, A.; Fukazawa, Y.; Funk, S.; Fusco, P.; Gargano, F.; Gasparrini, D.; Giebels, B.; Giglietto, N.; Giommi, P.; Giordano, F.; Giroletti, M.; Glanzman, T.; Godfrey, G.; Grenier, I. A.; Grondin, M.-H.; Grove, J. E.; Guillemot, L.; Guiriec, S.; Hadasch, D.; Harding, A. K.; Hays, E.; Hewitt, J. W.; Hill, A. B.; Horan, D.; Iafrate, G.; Jogler, T.; Johannesson, G.; Johnson, R. P.; Johnson, A. S.; Johnson, T. J.; Johnson, W. N.; Kamae, T.; Kataoka, J.; Katsuta, J.; Kuss, M.; La Mura, G.; Landriu, D.; Larsson, S.; Latronico, L.; Lemoine-Goumard, M.; Li, J.; Li, L.; Longo, F.; Loparco, F.; Lott, B.; Lovellette, M. N.; Lubrano, P.; Madejski, G. M.; Massaro, F.; Mayer, M.; Mazziotta, M. N.; McEnery, J. E.; Michelson, P. F.; Mirabal, N.; Mizuno, T.; Moiseev, A. A.; Mongelli, M.; Monzani, M. E.; Morselli, A.; Moskalenko, I. V.; Murgia, S.; Nuss, E.; Ohno, M.; Ohsugi, T.; Omodei, N.; Orienti, M.; Orlando, E.; Ormes, J. F.; Paneque, D.; Panetta, J. H.; Perkins, J. S.; Pesce-Rollins, M.; Piron, F.; Pivato, G.; Porter, T. A.; Racusin, J. L.; Rando, R.; Razzano, M.; Razzaque, S.; Reimer, A.; Reimer, O.; Reposeur, T.; Rochester, L. S.; Romani, R. W.; Salvetti, D.; Sanchez-Conde, M.; Saz Parkinson, P. M.; Schulz, A.; Siskind, E. J.; Smith, D. A.; Spada, F.; Spandre, G.; Spinelli, P.; Stephens, T. E.; Strong, A. W.; Suson, D. J.; Takahashi, H.; Takahashi, T.; Tanaka, Y.; Thayer J. G, .; Thayer, J. B.; Thompson, D. J.; Tibaldo, L.; Tibolla, O.; Torres, D. F.; Torresi, E.; Tosti, G.; Troja, E.; van Klaveren, B.; Vianello, G.; Winer, B. L.; Wood, K. S.; Wood, M.; Zimmer, S.

    2015-08-01

    The data for the 3FGL catalog were taken during the period from 2008 August 4 (15:43 UTC) to 2012 July 31 (22:46 UTC), to covering close to 4yr. The LAT detects γ-rays in the energy range from 20MeV to more than 300GeV. (3 data files).

  5. Anthocyanins Present in Some Tropical Fruits.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Many tropical fruits are rich in anthocyanins, though limited information is available about the characterization and quantification of these anthocyanins. The identification of anthocyanin pigments in four tropical fruits was determined by ion trap mass spectrometry. Fruits studied included acero...

  6. 76 FR 774 - Light-Walled Rectangular Pipe and Tube From Mexico: Extension of Time Limit for Final Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... Mexico: Preliminary Results of Antidumping Duty Administrative Review, 75 FR 55559 (September 13, 2010... FR at 55567. Respondent companies Nacional de Acero S.A. de C.V., Regiomontana de Perfiles y Tubos S... 13, 2010. On October 18, 2010, the domestic interested parties (Atlas Tube, Bull Moose Tube...

  7. ATel 7545: Fermi LAT Detection of a GeV flare from spectrally hard FSRQ S4 1800+44

    NASA Astrophysics Data System (ADS)

    Buson, S.; Fermi LAT Collaboration

    2015-05-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux and an unusually hard gamma-ray spectrum from a source positionally consistent with the flat spectrum radio quasar (FSRQ) S4 1800+44 (also known as 3FGL J1801.5+4403, Acero et al. ...

  8. Fermi-LAT detection of hard spectrum gamma-ray activity from the FSRQ PKS 1532+01

    NASA Astrophysics Data System (ADS)

    Ciprini, S.; Cheung, C. C.

    2015-03-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux and an unusually hard gamma-ray spectrum from a source positionally consistent with the flat spectrum radio quasar (FSRQ) PKS 1532+01 (also known as 3FGL J1534.5+0128, Acero et al.

  9. ATel 7453: Fermi LAT detection of a GeV flare from the FSRQ PKS 2032+107

    NASA Astrophysics Data System (ADS)

    Orienti, M.; D'Ammando, F.; Fermi Large Area Telescope Collaboration

    2015-04-01

    The Large Area Telescope (LAT), on board the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the flat spectrum radio quasar PKS 2032+107 (also known as 3FGL J2035.3+1055, Acero et al. ...

  10. Fermi LAT detection of increasing gamma-ray activity from NGC 1275 and B3 0908+416B

    NASA Astrophysics Data System (ADS)

    Pivato, G.; Buson, S.

    2015-10-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from sources positionally consistent with the flat spectrum radio quasar B3 0908+416B (also known as 3FGL J0912.2+4126, Acero et al. 2015 ApJS, 218, 23) and the radio galaxy NGC 1275 (also known as Perseus A and 3FGL J0319.8+4130).

  11. Fermi LAT detection of renewed and strong GeV activity from blazar 3C 279

    NASA Astrophysics Data System (ADS)

    Cutini, Sara

    2015-06-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed an intense gamma-ray flare from a source positionally consistent with the flat spectrum radio quasar 3C 279, also known as 3FGL J1256.1-0547 (Acero et al. 2015, APJS, 218, 23), with radio coordinates R.A.: 194.0465271 deg, Dec: -5.7893119 deg (J2000.0; Johnston et al. 1995, AJ, 110, 880).

  12. El uso de la neuromodulación para el tratamiento del temblor

    PubMed Central

    Bendersky, Damián; Ajler, Pablo; Yampolsky, Claudio

    2014-01-01

    Introducción: El temblor puede ser un desorden incapacitante y el tratamiento de primera línea para estos pacientes es farmacológico. Sin embargo, este tratamiento puede llevar a una reducción satisfactoria del temblor en sólo el 50% de los pacientes con temblor esencial. La talamotomía era el tratamiento de elección para el temblor refractario al tratamiento médico hasta que comenzó a utilizarse la estimulación cerebral profunda (ECP) del núcleo ventral intermedio (Vim) del tálamo. En la actualidad, raramente se realiza la talamotomía. Métodos: Este artículo es una revisión no sistemática de las indicaciones, resultados, parámetros de programación y técnica quirúrgica de la ECP del Vim para el tratamiento del temblor. Resultados: Aunque los resultados clínicos son similares usando la talamotomía o la ECP del Vim, la primera causa más efectos adversos que la última. Además, la ECP puede ser usada bilateralmente, mientras que la talamotomía tiene un alto riesgo de causar disartria cuando se realiza de ambos lados. La ECP del Vim logró una adecuada mejoría del temblor en varias series de pacientes con temblor causado por temblor esencial, enfermedad de Parkinson o esclerosis múltiple. Además del Vim, hay otros blancos que están siendo usados por varios autores, tales como la zona incerta y las radiaciones prelemniscales. Conclusión: La ECP del Vim es un tratamiento útil para el temblor incapacitante refractario al tratamiento médico. Es esencial realizar una precisa selección de pacientes, así como utilizar una técnica quirúrgica correcta. Aún se desconoce el mejor blanco estereotáctico para el temblor, aunque el Vim es el más usado. PMID:25165613

  13. Fermi LAT and Swift flare of the FSRQ 4C +40.25

    NASA Astrophysics Data System (ADS)

    Carpenter, Bryce; Ojha, Roopesh; Pivato, Giovanna; Fermi Large Area Telescope Collaboration

    2015-11-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed a gamma-ray flare from a source positionally consistent with the flat spectrum radio quasar (FSRQ) 4C +40.25 (also known as B2 1020+40 and 3FGL J1023.1+3952, Acero et al. 2015, ApJS 218, 23) with coordinates RA: 10h 23m 11.5661s, Dec: 39d 48m 15.378s, J2000, (Helmboldt et al. 2007, ApJ, 658, 203) and a redshift of 1.254 (Xu et al. 1994, AJ, 108, 395).

  14. Fermi LAT Detection of a Gamma-ray Flare from the BL Lac Object ON 246

    NASA Astrophysics Data System (ADS)

    Becerra, Josefa

    2015-06-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed increasing gamma-ray flux from a source positionally consistent with the BL Lac object ON 246 (RA=187.55871 deg, Dec=25.30198 deg, J2000, Beasley et al. 2002, ApJS, 141, 13; with redshift z=0.135, Nass et al. 1996, A&A, 309, 419), also known as S3 1227+25 and 3FGL J1230.3+2519 (3FGL; Acero et al. 2015, arXiv:1501.02003).

  15. Fermi-LAT detection of hard spectrum and high-level gamma-ray flare from the blazar PKS 1954-388

    NASA Astrophysics Data System (ADS)

    Cutini, Sara; Ciprini, Stefano; Fermi Large Area Telescope Collaboration

    2015-09-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed flaring gamma rays from a source positionally consistent with the flat spectrum radio quasar PKS 1954-388 (also known as MRC 1954-388, RX J1958.0-3845, and 3FGL J1958.0-3847, Acero et al. 2015, ApJS 218, 23), with radio coordinates, (J2000.0), R.A.: 299.499247 deg, Dec.: -38.751766 deg, (Ma et. al. 1998, AJ, 116, 516).

  16. Fermi-LAT detection of hard spectrum and highest-level gamma-ray outburst from the distant blazar PKS 1502+106

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano; Fermi Large Area Telescope Collaboration

    2015-07-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed flaring gamma rays from a source positionally consistent with the flat spectrum radio quasar PKS 1502+106 (also known as OR 103, S3 1502+10 and 3FGL J1504.4+1029, Acero et al. 2015, ApJS 218, 23), with radio coordinates, (J2000.0), R.A.: 226.10408 deg, Dec: 10.49422 deg (Johnston et al. 1995, AJ, 110, 880). This blazar has a redshift of z=1.8383 (Hewett & Wild 2010, MNRAS, 405, 2302).

  17. Fermi-LAT detection of hard spectrum gamma-ray flare from FSRQ S4 1800+44

    NASA Astrophysics Data System (ADS)

    Gasparrini, D.; Buson, S.

    2016-03-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux and an unusually hard gamma-ray spectrum from a source positionally consistent with the flat spectrum radio quasar (FSRQ) S4 1800+44 (also known as 3FGL J1801.5+4403, Acero et al. 2015, ApJS, 218, 23) with radio counterpart coordinates (J2000.0), R.A. = 270.3846454 deg, Dec. = 44.0727500 deg (Johnston et al. 1995, AJ, 110, 880).

  18. Fermi-LAT detection of hard spectrum and enhanced gamma-ray emission from the BL Lac object PKS 1717+177

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano

    2015-12-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed a gamma-ray flare from a source positionally consistent with the BL Lac object PKS 1717+177 (also known as S3 1717+17, OT 129, and 3FGL J1719.2+1744, Acero et al. 2015, ApJS, 218, 23), with radio coordinates (J2000.0), R.A.: 259.804368 deg, Dec.: 17.751788 deg (Johnston et al. 1995, AJ, 110, 880).

  19. Fermi-LAT detection of strong flaring activity from the FSRQ CTA 102

    NASA Astrophysics Data System (ADS)

    Becerra, J.; Carpenter, Bryce; Cutini, Sara

    2016-02-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed increasing gamma-ray activity from a source positionally consistent with the flat spectrum radio quasar CTA 102 (also known as 3FGL J2232.5+1143, Acero et al. 2015, ApJS, 218, 23) with radio coordinates R.A.: 338.1517038 deg, Dec: 11.7308067 deg (J2000, Johnston et al. 1995, AJ, 110, 880) at redshift z=1.037 (Schmidt 1965, ApJ, 141, 1295).

  20. Fermi LAT detection of renewed activity from the blazar PKS 1502+106

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano

    2015-06-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 1502+106 (also known as OR 103, S3 1502+10 and 3FGL J1504.4+1029, Acero et al., arXiv:1501.02003), with radio coordinates, (J2000.0), R.A.: 226.10408 deg, Dec: 10.49422 deg (Johnston et al. 1995, AJ, 110, 880). This blazar has a redshift of z=1.8383 (Hewett & Wild 2010, MNRAS, 405, 2302).

  1. Fermi LAT detection of increasing GeV gamma-ray activity from the high-energy peaked BL Lac object 1ES 1959+650

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano; Fermi Large Area Telescope Collaboration

    2015-10-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray emission from a source positionally consistent with the very-high energy peaked BL Lac object 1ES 1959+650 (also known as TXS 1959+650 and 3FGL J2000.0+6509, Acero et al. 2015, ApJS 218, 23) with radio coordinates (J2000) R.A.: 299.999384 deg, Dec.: 65.148514 deg (Beasley et al. 2002, ApJS, 141, 13). This source has a redshift z=0.047 (Schachter et al. 1993, ApJ, 412, 541).

  2. Fermi LAT Detection of a Rapid, Powerful Gamma-ray Flare of the FSRQ CTA 102

    NASA Astrophysics Data System (ADS)

    Carpenter, Bryce; Ojha, Roopesh

    2015-12-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar CTA 102 (also known as 3FGL J2232.5+1143, Acero et al. 2015, ApJS, 218, 23) with radio coordinates R.A.: 338.1517038 deg, Dec: 11.7308067 deg (J2000, Johnston et al. 1995, AJ, 110, 880) at redshift z=1.037 (Schmidt 1965, ApJ, 141, 1295).

  3. Fermi-LAT, FACT, MAGIC and VERITAS detection of increasing gamma-ray activity from the high-energy peaked BL Lac object 1ES 1959+650

    NASA Astrophysics Data System (ADS)

    Buson, S.; Magill, J. D.; Dorner, D.; Biland, A.; Mirzoyan, R.; Mukherjee, R.

    2016-04-01

    The Fermi-LAT, FACT, MAGIC and VERITAS collaborations report the detection of enhanced gamma-ray activity from a source positionally consistent with the very-high-energy peaked BL Lac object 1ES 1959+650 (a.k.a 3FGL J2000.0+6509, in the 3rd LAT source catalog, 3FGL, Acero et al. 2015, ApJS 218, 23) with radio coordinates (J2000) R.A.: 299.999384 deg, Dec.: 65.148514 deg (Beasley et al. 2002, ApJS, 141, 13). This source has a redshift z=0.047 (Schachter et al. 1993, ApJ, 412, 541).

  4. Fermi-LAT Detection of a Hard Spectrum and Enhanced Gamma-ray Emission from the Blazar PMN J2052-5533

    NASA Astrophysics Data System (ADS)

    Carpenter, Bryce; Magill, Jeff; Ojha, Roopesh

    2015-09-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed an unusually hard spectrum gamma-ray flare from a source positionally consistent with the blazar PMN J2052-5533 (3FGL J2051.8-5535; Acero et al. 2015, ApJS 218, 23), with coordinates RA: 20h52m13.68s, Dec: -55d33m10.0s, J2000, (Healey et al. 2007, ApJS, 171, 61). There is no redshift reported for this source in the literature.

  5. Fermi LAT detection of the first GeV gamma-ray flare from the BL Lac object TXS 2241+406

    NASA Astrophysics Data System (ADS)

    Buson, Sara

    2015-02-01

    The Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope, has observed for the first time on daily timescales gamma-ray outburst activity from a source positionally consistent with the BL Lac object TXS 2241+406 (a.k.a.3FGL J2244.1+4057, Acero et al. 2015, arXiv:1501.02003) at RA=341.05305 deg, Dec=40.95378 deg (J2000, Beasley et al. 2002, ApJS, 141, 13) with redshift z=1.171 (Shaw et al. 2012, ApJ, 748, 49).

  6. Fermi LAT detection of increasing gamma-ray emission from the radio-loud NLSy1 PKS 1502+036

    NASA Astrophysics Data System (ADS)

    D'Ammando, Filippo; Ciprini, Stefano

    2015-12-01

    The Large Area Telescope (LAT), on board the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the radio-loud narrow-line Seyfert 1 PKS 1502+036 (also known as 3FGL J1505.1+0326, Acero et al. 2015, ApJS, 218, 23), with radio coordinates (J2000.0), R.A.: 226.2769879 deg, Dec.: 3.4418922 deg (Fey et al. 2004, AJ, 127, 3587) at redshift z = 0.4078 (Hewett & Wild 2010, MNRAS, 405, 2302).

  7. [Temporal lobe epilepsy and active neurocysticercosis: two representative case reports].

    PubMed

    Ramos-Zúñiga, Rodrigo; Pérez-Gómez, Héctor R; Gaytán-Martínez, Luis A; Vega-Ruiz, Brenda; Soto-Rodríguez, Sofía; Rochín-Mozqueda, Alejandro

    2015-01-01

    Introduccion. Existen pocas evidencias notificadas de casos de epilepsia del lobulo temporal asociadas a cisticercosis activa en su fase quistica. El objetivo es presentar la correlacion entre cisticercosis activa en zonas topograficas asociadas a epilepsia del lobulo temporal, con las manifestaciones neuropsiquiatricas y el patron de crisis parciales secundariamente generalizadas. Casos clinicos. Dos casos de pacientes adultos con manifestaciones neuropsiquiatricas de un año de evolucion, refractarios a tratamiento farmacologico antipsicotico, y en quienes posteriormente aparecen crisis convulsivas parciales secundariamente generalizadas de inicio tardio. Se identifica la presencia de cisticercosis activa en el lobulo temporal en un paciente, y en la insula, en el otro. Buen control clinico posterior al tratamiento con albendazol, pero se mantiene el mismo tratamiento anticonvulsionante para considerar la pertinencia de su retirada farmacologica. Conclusiones. La neurocisticercosis activa puede ser causa de trastornos neuropsiquiatricos adquiridos y de epilepsia del lobulo temporal de inicio tardio cuando su topografia se encuentra en el circuito mesolimbico. El diagnostico etiologico oportuno y el tratamiento apropiado permiten el control adecuado de su sintomatologia y, potencialmente, su curacion definitiva.

  8. [Effectiveness of lacosamide in the treatment of refractory neuropathic pain: an open observational trial].

    PubMed

    Gómez-Argüelles, José M; Bermejo, Pedro E; Lara, Manuel; Almajano, Jerónimo; Aragón, Esther; García del Carrizo, Fernando; Blanco, M Victoria; Valenzuela-Rojas, Francisco J; Colás, Juan; Sánchez-Del Valle, Octavio; Ceballos, M Ángeles; Toribio-Díaz, M Elena; Latorre-González, Germán; Costa-Frossard, Lucienne; Morin-Martin, M del Mar

    2014-10-01

    Introduccion. Aunque se dispone de diferentes tratamientos para el dolor neuropatico, en muchas ocasiones estos pacientes son refractarios, lo que hace necesario probar tratamientos que, por su utilidad en otras patologias, podrian ser eficaces en el dolor neuropatico. Pacientes y metodos. Se recogieron las historias clinicas de pacientes que hubieran sido tratados con lacosamida para el dolor neuropatico, en diferentes hospitales de la zona centro peninsular, y que cumplieran unas caracteristicas similares en cuanto a refractariedad a otros tratamientos estandares, en un seguimiento de al menos seis meses, o que hubiesen tenido que suspender el tratamiento con dicho farmaco por cualquier motivo. Se obtuvo una muestra de 114 pacientes, 61 varones y 53 mujeres, con una edad media de 60,5 años. Resultados. Las causas de dolor neuropatico mas frecuentes fueron: polineuropatia diabetica (31,6%), neuralgia postherpetica (22,8%), neuralgia del trigemino (17,5%), neuralgia suboccipital y lumbociatalgia (un 12,3% en ambas). La eficacia fue buena/muy buena en la mayoria de los pacientes, con un descenso medio en la escala analogica visual tras seis meses de 7,7 a 4,8. No se registraron efectos secundarios graves en ningun paciente, pero en 12 y 10 pacientes no hubo registro mas alla de seis meses, por ineficacia e intolerancia al tratamiento, respectivamente. Conclusiones. El tratamiento con lacosamida en el dolor neuropatico de diferentes causas podria considerarse como una alternativa efectiva y bien tolerada para aquellos pacientes que no respondan a los tratamientos estandares.

  9. [The use of the ketogenic diet as treatment for refractory epilepsy in the paediatric age].

    PubMed

    Pablos-Sánchez, Tamara; Oliveros-Leal, Liliana; Núñez-Enamorado, Noemí; Camacho-Salas, Ana; Moreno-Villares, José Manuel; Simón-De las Heras, Rogelio

    2014-01-16

    Introduccion. El 23-25% de los niños epilepticos son refractarios a farmacos antiepilepticos. El interes por la dieta cetogenica como tratamiento en estos pacientes no candidatos a otras opciones terapeuticas ha resurgido ultimamente. Objetivo. Valorar la eficacia y seguridad del tratamiento con dieta cetogenica en un importante numero de pacientes pediatricos con epilepsia refractaria en nuestro centro y determinar si los resultados obtenidos corroboran otros de publicacion reciente. Pacientes y metodos. Se revisaron retrospectivamente las historias clinicas de 41 niños con epilepsia refractaria que fueron tratados con dieta cetogenica entre 1998 y 2011, la mayoria con dieta tipo Radcliffe II. La mediana de edad al inicio de la dieta fue de 3,92 años. Resultados. A los seis meses del inicio de la dieta se redujeron las crisis en al menos un 50% en un 36,84% de la muestra (el 10,53% de los niños alcanzo mas de un 90% de reduccion y un 5,26% quedo sin crisis). Aproximadamente un 50% por grupo de edad en los mas pequeños respondio de manera positiva. Un 58,54% de los pacientes presento algun efecto secundario, tolerable y transitorio, principalmente elevacion de los niveles de colesterol y estreñimiento, sin observarse variacion en los parametros antropometricos. Conclusiones. La dieta cetogenica supone una buena alternativa terapeutica en los casos de epilepsia refractaria en la edad pediatrica, con mayor probabilidad de beneficio cuanto menor sea la edad del niño al inicio de la dieta. En general, es bien tolerada. Son de gran importancia en estos pacientes las revisiones periodicas con control nutricional.

  10. [Lacosamide and neuropathic pain, a review].

    PubMed

    Alcántara-Montero, Antonio; Sánchez-Carnerero, Clara I

    2016-03-01

    Introduccion. La mayor parte de las guias de practica clinica consultadas coinciden en señalar que los antidepresivos triciclicos, duales (venlafaxina/duloxetina), antiepilepticos gabapentina/pregabalina, apositos de lidocaina al 5% y parches de capsaicina al 8% constituyen los farmacos de primera linea en el tratamiento del dolor neuropatico periferico, y el tramadol y algunos opioides potentes (morfina, oxicodona y tapentadol) son farmacos de segunda linea. Por otra parte, la prevalencia de dolor neuropatico refractario al tratamiento se acerca al 1,5% de la poblacion, de forma que se calcula que un 50% de los pacientes no responde al tratamiento prescrito. Existen otros antiepilepticos que no tienen indicacion en el dolor neuropatico por las agencias reguladoras, como la lamotrigina, el topiramato o la oxcarbacepina, pero se utilizan en la practica clinica habitual fuera de indicacion. Desarrollo. Tras una busqueda bibliografica, se realizo una revision sobre el empleo de la lacosamida en el dolor neuropatico, tanto en distintos modelos animales como en diferentes estudios en humanos. Conclusiones. El tratamiento con lacosamida en el dolor neuropatico de diferentes etiologias podria considerarse como una alternativa efectiva para los pacientes que no respondan o no toleren los tratamientos estandares. Sin embargo, la mayor parte de la evidencia disponible, a excepcion de los ensayos clinicos en fase II/III realizados en el dolor neuropatico diabetico, corresponde a estudios abiertos y observacionales, sin grupo control y con bajo numero de pacientes, pero los resultados favorables obtenidos invitan a seguir investigando la utilidad de la lacosamida en el dolor neuropatico.

  11. Occurrence of Cryptosporidium oocysts in Wrinkled Hornbill and other birds in the Kuala Lumpur National Zoo.

    PubMed

    Rohela, M; Lim, Y A L; Jamaiah, I; Khadijah, P Y Y; Laang, S T; Nazri, M H Mohd; Nurulhuda, Z

    2005-01-01

    The occurrence of a coccidian parasite, Cryptosporidium, among birds in the Kuala Lumpur National Zoo was investigated in this study. A hundred bird fecal samples were taken from various locations of the zoo. Fecal smears prepared using direct smear and formalin ethyl acetate concentration technique were stained with modified Ziehl-Neelsen stain. Samples positive for Cryptosporidium with Ziehl-Neelsen stain were later confirmed using the immunofluorescence technique and viewed under the epifluorescence microscope. Six species of bird feces were confirmed positive with Cryptosporidium oocysts. They included Wrinkled Hornbill (Aceros corrugatus), Great Argus Pheasant (Argusianus argus), Black Swan (Cygnus atratus), Swan Goose (Anser cygnoides), Marabou Stork (Leptoptilos crumeniferus), and Moluccan Cockatoo (Cacatua moluccencis). These birds were located in the aviary and lake, with the Moluccan Cockatoo routinely used as a show bird. Results obtained in this study indicated that animal sanctuaries like zoos and bird parks are important sources of Cryptosporidium infection to humans, especially children and other animals.

  12. Discovery of a Fanaroff-Riley type 0 radio galaxy emitting at γ-ray energies

    NASA Astrophysics Data System (ADS)

    Grandi, Paola; Capetti, Alessandro; Baldi, Ranieri D.

    2016-03-01

    We present supporting evidence for the first association of a Fermi source, 3FGLJ1330.0-3818, Acero et al. (2015) with the Fanaroff-Riley type 0 (FR 0) radio galaxy Tol1326-379. FR 0s represent the majority of the local population of radio-loud active galactic nuclei but their nature is still unclear. They share the same nuclear and host properties as FR Is, but they show a large deficit of extended radio emission. Here we show that FR 0s can emit photons at very high energies. Tol1326-379 has a GeV luminosity of L>1 GeV ˜ 2 × 1042 erg s-1, typical of FR Is, but with a steeper γ-ray spectrum (Γ = 2.78 ± 0.14). This could be related to the intrinsic jet properties but also to a different viewing angle.

  13. Fermi and Swift observations of a rapid flare in the BL Lac object SDSS J084411.67+531250.7 (NVSS J084411+531250)

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano

    2015-04-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the optically-selected and polarized (Smith et al. 2007, ApJ, 663, 118) BL Lac object SDSS J084411.67+531250.7 (also known as NVSS J084411+531250, BZB J0844+5312, and 3FGL J0843.9+5311, Acero et al. 2015, arXiv:1501.02003), with optical counterpart coordinates (J2000.0) R.A.: 131.04872 deg, Dec.: 53.21407 deg (Adelman-McCarthy et. al 2008, ApJS, 175, 297).

  14. Gamma-rays from pulsar wind nebulae in starburst galaxies

    NASA Astrophysics Data System (ADS)

    Mannheim, Karl; Elsässer, Dominik; Tibolla, Omar

    2012-07-01

    Recently, gamma-ray emission at TeV energies has been detected from the starburst galaxies NGC253 (Acero et al., 2009) [1] and M82 (Acciari et al., 2009) [2]. It has been claimed that pion production due to cosmic rays accelerated in supernova remnants interacting with the interstellar gas is responsible for the observed gamma rays. Here, we show that the gamma-ray pulsar wind nebulae left behind by the supernovae contribute to the TeV luminosity in a major way. A single pulsar wind nebula produces about ten times the total luminosity of the Sun at energies above 1 TeV during a lifetime of 105 years. A large number of 3 × 104 pulsar wind nebulae expected in a typical starburst galaxy at a distance of 4 Mpc can readily produce the observed TeV gamma rays.

  15. Gamma-ray flares from the blazars TXS 2241+406, Ton 599, and 4C +01.02

    NASA Astrophysics Data System (ADS)

    Ojha, Roopesh; Carpen, Bryce

    2015-11-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed a gamma-ray flare from a source positionally consistent with the BL Lac object TXS 2241+406 (3FGL J2244.1+4057, Acero et al. 2015, ApJS 218, 23) with coordinates RA=22h 44m 12.7311s, Dec=40d 57m 13.62s (J2000, Beasley et al. 2002, ApJS, 141, 13) with redshift z=1.171 (Shaw et al. 2012, ApJ, 748, 49). Preliminary analysis indicates that on 20 November 2015 this source was in a high-flux state, with a daily averaged gamma-ray flux (E > 100MeV) of (1.2+/-0.2) X 10^-6 photons cm^-2 s^-1 (statistical uncertainty only) and photon spectral index of 2.2+/-0.1 (errors are statistical only).

  16. Fermi-LAT confirmation of enhanced gamma-ray activity from the Crab nebula

    NASA Astrophysics Data System (ADS)

    Cheung, C. C.

    2016-10-01

    Preliminary LAT analysis confirms the recent enhanced gamma-ray activity from the Crab nebula detected by AGILE (ATel #9586). The daily-averaged gamma-ray fluxes (E > 100 MeV) from the direction of the Crab Nebula were (4.8 +/- 0.5) x 10^-6 ph cm^-2 s^-1 (Sep 30), (3.3 +/- 0.4) x 10^-6 ph cm^-2 s^-1 (Oct 1), and (4.5 +/- 0.5) x 10^-6 ph cm^-2 s^-1 (Oct 2). These are up to a factor of ~1.8 greater than the average gamma-ray flux of (2.71 +/- 0.02) x 10^-6 ph cm^-2 s^-1 reported in the third Fermi-LAT source catalog (Acero et al. 2015, ApJS, 218, 23). All fluxes given are the sums of the pulsar and nebular emission, and with statistical uncertainties only.

  17. Estudio del comportamiento tribologico y de las interacciones de superficie de nuevos nanofluidos ionicos

    NASA Astrophysics Data System (ADS)

    Espinosa Rodriguez, Tulia

    tribocorrosion processes. The formation of a coating layer on magnesium alloys from phosphonate imidazolium ionic liquids by immersion and by chronoamperometry has been described. The new coatings reduce the abrasive wear in the magnesium-aluminium alloy but they are not effective in the magnesium-zinc alloy, which prevent the formation of continuous coatings. Los liquidos ionicos son sales liquidas a temperatura ambiente o bajas temperaturas que presentan excelentes propiedades fisico-quimicas. En el presente trabajo se estudian como lubricantes en problemas tribologicos complejos como la lubricacion de metales contra si mismos, el desarrollo de lubricantes base agua y de nuevas superficies autolubricadas. Cuando no es posible reducir la friccion y desgaste mediante lubricacion, como en las aleaciones de magnesio, los liquidos ionicos se han estudiado como precursores de recubrimientos protectores. Se han determinado las interacciones superficiales y los procesos de corrosion sobre cobre y sobre acero con diferentes liquidos ionicos proticos y aproticos para desarrollar nuevos lubricantes y aditivos. En el contacto cobre/cobre, excepto el liquido ionico protico derivado del oleato, todos los liquidos ionicos estudiados presentan mejor comportamiento tribologico que el lubricante comercial Polialfaolefina 6. En el contacto acero/zafiro, los nuevos liquidos ionicos proticos son buenos lubricantes cuando se utilizan en estado puro, y, como aditivos en agua, generan peliculas adsorbidas sobre la superficie del metal reduciendo la friccion y el desgaste tras la evaporacion del agua. Para evitar el periodo de alta friccion inicial en presencia de agua, se han generado peliculas superficiales de liquido ionico sobre el acero en condiciones estaticas. El mejor comportamiento lubricante tanto en el contacto cobre/cobre como en el contacto acero/zafiro se obtiene para el liquido ionico protico derivado del anion adipato, con dos grupos carboxilicos. Las interacciones de los grupos

  18. [Clinical experience with lacosamide in Galicia: the GALACO study].

    PubMed

    Rodriguez-Osorio, Xiana; Lopez-Gonzalez, Francisco J; Pato-Pato, Antonio; Cebrian-Perez, Ernesto; Marey-Lopez, José; Corredera-Garcia, Enrique; Rubio-Nazabal, Eduardo; Castro-Vilanova, M Dolores; Abella-Corral, Javier; Rodriguez-Regal, Ana; Amigo-Jorrin, M Campo; Pego-Reigosa, Robustiano

    2015-12-16

    Introducción. La lacosamida es un fármaco antiepiléptico bloqueante de los canales de sodio, autorizado en adolescentes y adultos como tratamiento coadyuvante en crisis de inicio focal. Objetivo. Analizar los resultados de eficacia y seguridad de la lacosamida en Galicia en su uso de acuerdo con la práctica clínica habitual. Pacientes y métodos. Estudio retrospectivo observacional en pacientes que iniciaron tratamiento con lacosamida entre enero de 2013 y junio de 2014 en 10 hospitales de Galicia. Se evaluó su eficacia y seguridad a los 3, 6 y 12 meses del inicio del tratamiento. Resultados. Se incluyeron 184 pacientes con edad media de 44,2 ± 17,4 años; el 56,5% (n = 104) eran varones. Conforman la población de eficacia 173 pacientes. El tiempo medio de evolución de la epilepsia fue de 18,8 ± 15,5 años. La frecuencia de crisis era de 2,5 ± 1,6 episodios/mes. A los 12 meses, el 68,2% de los pacientes (n = 118) presentaba una mejoría igual o superior al 50% (pacientes respondedores) y, de ellos, 54 (el 45,8% de los respondedores) estaban libres de crisis. El 23,4% (n = 43) refirió efectos adversos a los 12 meses, principalmente mareos (10,3%) e inestabilidad (3,3%). Después de la visita de los 12 meses, continuaba con lacosamida el 87,5% de los pacientes (n = 161). Conclusiones. La lacosamida ofrece un perfil de eficacia y seguridad muy favorable para pacientes con epilepsia focal refractaria. El elevado porcentaje de respondedores podría atribuirse a una población de epilépticos menos refractarios que en otros estudios de práctica clínica. Constituye una opción terapéutica atractiva para el tratamiento de epilepsias de inicio focal.

  19. First Fermi LAT detection of a strong GeV gamma-ray flare from blazar PKS 0403-13

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano

    2016-07-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 0403-13 (also known as TXS 0403-132, OF -105, RX J0405.5-1308, and 3FGL J0405.5-1307), with radio counterpart position R.A.: 61.391680 deg, Dec.: -13.137136 deg (J2000.0, Fey et al. 2004, AJ, 127, 3587) and with redshift z=0.5706+/-0.0001 (Marziani et al. 1996, ApJS, 104, 37). Preliminary analysis indicates that on 2016 July 11, PKS 0403-13 was in a high state with a daily averaged gamma-ray flux (E > 100 MeV) of (1.6+/-0.3) X 10^-6 photons cm^-2 s^-1 (statistical uncertainty only), about 140 times greater than its four-year average flux reported in the third Fermi-LAT source catalog (3FGL, Acero et al. 2015, ApJS, 218, 23). The corresponding daily averaged spectral photon index (E > 100 MeV) of 2.3+/-0.2 (statistical uncertainty only) is compatible with the 3FGL catalog value of 2.35+/-0.11.

  20. Fermi-LAT Detection of an Unusual Hard Spectrum and Enhanced Gamma-ray Emission from the FSRQ PKS B1035-281

    NASA Astrophysics Data System (ADS)

    Carpenter, Bryce; Ojha, Roopesh

    2016-02-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed increasing gamma-ray flux and an unusually hard spectrum from a source positionally consistent with the flat spectrum radio quasar PKS B1035-281 (also known as 3FGL J1037.5-2821, Acero et al. 2015, ApJS, 218, 23) with radio coordinates R.A.: 159.4269058 deg, Dec: -28.3844750 deg (J2000, Beasley et al. 2002, ApJS, 141, 13) at redshift z=1.066 (Shaw et al. 2012, ApJ, 748, 49). Preliminary analysis indicates that on 24 February 2016 this source was in a high-flux state, with a daily averaged gamma-ray flux (E > 100MeV) of (0.7+/-0.1) X 10^-6 photons cm^-2 s^-1 (statistical uncertainty only) corresponding to a flux increase of a factor of about 30 over its four-year average flux (3FGL J1037.5-2821).

  1. VizieR Online Data Catalog: The cosmic TeV gamma-ray background spectrum (Inoue+, 2016)

    NASA Astrophysics Data System (ADS)

    Inoue, Y.; Tanaka, Y. T.

    2016-05-01

    We select 35 known extragalactic TeV sources which are located at Galactic latitude |b|>=10° and whose low activity state flux is available, since our aim is to give conservative constraints on the total cosmic gamma-ray background (CGB) in the TeV band. For each source, we select the lowest fluxes among several TeV measurements by modern imaging atmospheric Cherenkov telescopes (IACTs; H.E.S.S., MAGIC, and VERITAS) and further restrict samples showing no significant variability in the TeV band during observations. The sample contains 30 blazars, 3 radio galaxies, and 2 starburst galaxies from the default TeVcat catalog (Wakely & Horan 2008ICRC....3.1341W) which include published sources only. We also include the Fermi third source (3FGL) catalog data (Acero et al. 2015, J/ApJS/218/23) to cover GeV gamma-ray spectra. The 3FGL catalog is based on its first 48 months of survey data. All of our sample have counterparts in the 3FGL catalog. (2 data files).

  2. Linear lateral vibration of axisymmetric liquid briges

    NASA Astrophysics Data System (ADS)

    Ferrera, C.; Montanero, J. M.; Cabezas, M. G.

    A liquid bridge is a mass of liquid sustained by the action of the surface tension force between two parallel supporting disks Apart from their basic scientific interest a liquid bridge can be considered as the simplest idealization of the configuration appearing in the floating zone technique used for crystal growth and purification of high melting point materials footnote Messeguer et al emph Crystal Growth Res bf 5 27 1999 This has conferred considerable interest on the study of liquid bridges not only in fluid mechanics but also in the field of material engineering The axisymmetric dynamics of an isothermal liquid bridge has been frequently analysed over the past years The studies have considered different phenomena such as free oscillations footnote Montanero emph E J Mech B Fluids bf 22 169 2003 footnote Acero and Montanero emph Phys Fluids bf 17 078105 2005 forced vibrations footnote Perales and Messeguer emph Phys Fluids A bf 4 1110 1992 g-jitter effects footnote Messeguer and Perales emph Phys Fluids A bf 3 2332 1991 extensional deformation footnote Zhang et al emph J Fluid Mech bf 329 207 1996 and breakup process footnote Espino et al emph Phys Fluids bf 14 3710 2002 among others Works considering the nonaxisymmetric dynamical behaviour of a liquid bridge has been far less common footnote Sanz and Diez emph J Fluid Mech bf 205 503 1989 In the present study the linear vibration of an axisymmetric liquid

  3. Fermi-LAT detection of a GeV gamma-ray flare from the blazar PKS 2023-07

    NASA Astrophysics Data System (ADS)

    Ciprini, Stefano; Fermi Large Area Telescope Collaboration

    2016-04-01

    The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 2023-07 (also known as NRAO 629, TXS 2022-077, 3EG J2025-0744, 1AGLR J2027-0747 and 3FGL J2025.6-0736), with radio counterpart position R.A.: 306.419418 deg, Dec.: -7.597969 deg (J2000.0, Beasley et al. 2002, ApJS, 141, 13) and with redshift z=1.388 (Drinkwater et al. 1997, MNRAS, 284, 85). Preliminary analysis indicates that on 2016 April 9, PKS 2023-07 was in a high state with a daily averaged gamma-ray flux (E > 100 MeV) of (2.0+/-0.3) X 10^-6 photons cm^-2 s^-1 (statistical uncertainty only), about 16 times greater than its four-year average flux reported in the third Fermi-LAT source catalog (3FGL, Acero et al. 2015, ApJS, 218, 23). The corresponding daily averaged spectral photon index (E > 100 MeV) of 2.4+/-0.2 (statistical uncertainty only) is compatible with the 3FGL catalog value of 2.18+/-0.03.

  4. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease

    PubMed Central

    Karmouty-Quintana, Harry; Zhong, Hongyan; Acero, Luis; Weng, Tingting; Melicoff, Ernestina; West, James D.; Hemnes, Anna; Grenz, Almut; Eltzschig, Holger K.; Blackwell, Timothy S.; Xia, Yang; Johnston, Richard A.; Zeng, Dewan; Belardinelli, Luiz; Blackburn, Michael R.

    2012-01-01

    Development of pulmonary hypertension is a common and deadly complication of interstitial lung disease. Little is known regarding the cellular and molecular mechanisms that lead to pulmonary hypertension in patients with interstitial lung disease, and effective treatment options are lacking. The purpose of this study was to examine the adenosine 2B receptor (A2BR) as a regulator of vascular remodeling and pulmonary hypertension secondary to pulmonary fibrosis. To accomplish this, cellular and molecular changes in vascular remodeling were monitored in mice exposed to bleomycin in conjunction with genetic removal of the A2BR or treatment with the A2BR antagonist GS-6201. Results demonstrated that GS-6201 treatment or genetic removal of the A2BR attenuated vascular remodeling and hypertension in our model. Furthermore, direct A2BR activation on vascular cells promoted interleukin-6 and endothelin-1 release. These studies identify a novel mechanism of disease progression to pulmonary hypertension and support the development of A2BR antagonists for the treatment of pulmonary hypertension secondary to interstitial lung disease.—Karmouty-Quintana, H., Zhong, H., Acero, L., Weng, T., Melicoff, E., West, J. D., Hemnes, A., Grenz, A., Eltzschig, H. K., Blackwell, T. S., Xia, Y., Johnston, R. A., Zeng, D., Belardinelli, L., Blackburn, M. R. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. PMID:22415303

  5. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

    PubMed Central

    Karmouty-Quintana, Harry; Philip, Kemly; Acero, Luis F.; Chen, Ning-Yuan; Weng, Tingting; Molina, Jose G.; Luo, Fayong; Davies, Jonathan; Le, Ngoc-Bao; Bunge, Isabelle; Volcik, Kelly A.; Le, Thanh-Thuy T.; Johnston, Richard A.; Xia, Yang; Eltzschig, Holger K.; Blackburn, Michael R.

    2015-01-01

    Idiopathic pulmonary fibrosis (IPF) is a lethal, fibroproliferative disease. Pulmonary hypertension (PH) can develop secondary to IPF and increase mortality. Alternatively, activated macrophages (AAMs) contribute to the pathogenesis of both IPF and PH. Here we hypothesized that adenosine signaling through the ADORA2B on AAMs impacts the progression of these disorders and that conditional deletion of ADORA2B on myeloid cells would have a beneficial effect in a model of these diseases. Conditional knockout mice lacking ADORA2B on myeloid cells (Adora2Bf/f-LysMCre) were exposed to the fibrotic agent bleomycin (BLM; 0.035 U/g body weight, i.p.). At 14, 17, 21, 25, or 33 d after exposure, SpO2, bronchoalveolar lavage fluid (BALF), and histologic analyses were performed. On day 33, lung function and cardiovascular analyses were determined. Markers for AAM and mediators of fibrosis and PH were assessed. Adora2Bf/f-LysMCre mice presented with attenuated fibrosis, improved lung function, and no evidence of PH compared with control mice exposed to BLM. These findings were accompanied by reduced expression of CD206 and arginase-1, markers for AAMs. A 10-fold reduction in IL-6 and a 5-fold decrease in hyaluronan, both linked to lung fibrosis and PH, were also observed. These data suggest that activation of the ADORA2B on macrophages plays an active role in the pathogenesis of lung fibrosis and PH.—Karmouty-Quintana, H., Philip, K., Acero, L. F., Chen, N.-Y., Weng, T., Molina, J. G., Luo, F., Davies, J., Le, N.-B., Bunge, I., Volcik, K. A., Le, T.-T. T., Johnston, R. A., Xia, Y., Eltzschig, H. K., Blackburn, M. R. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. PMID:25318478

  6. A molecular dynamics study of the packing structures in monolayers of partially fluorinated amphiphiles

    NASA Astrophysics Data System (ADS)

    Shin, Seokmin; Collazo, Nancy; Rice, Stuart A.

    1992-01-01

    We report the results of molecular dynamics simulations of liquid-supported monolayers of three partially fluorinated amphiphile molecules, namely CF3(CF2)9CH2COOH, CF3(CF2)6CH2(CF2)3COOH, and CF3(CF2)6(CH2)4COOH. These studies were undertaken to provide information on the interplay between molecular flexibility and the packing structure in a monolayer so as to better interpret the results of recent experiments. The qualitative aspects of the predictions of the simulations are consistent with the recent experimental data for monolayers of CF3(CF2)9CH2COOH [S. W. Barton, A. Goudot, O. Boulassa, F. Rondelez, B. Lin, F. Novak, A. Acero, and S. A. Rice, J. Chem. Phys. 96, xxx (1992)]. In particular, the observed breakup of the homogeneous ordered monolayer into ordered islands with the same collective tilt of the molecules is correctly predicted, and the fact that the collective tilt angle is small is correctly predicted. However, the experimental and theoretical values of the tilt angles are not in quantitative agreement, which we attribute to the inadequacy of the atom-atom potentials used in the simulations. In general, for monolayers of CF3(CF2)9CH2COOH we find that the collective tilt angle predicted is a sensitive function of the area per molecule and is smaller than in monolayers of alkane alcohols and alkane acids. The results of the simulations of monolayers of other partially fluorinated species suggest that the difference in size between the fluorocarbon segments and the smaller head groups or flexible ``spacer'' CH2 segments can generate subtle changes in the packing structure of a monolayer and the relative stabilities of the untilted and tilted structures.

  7. Identifying the crystallinity, phase, and arsenic uptake of the nanomineral schwertmannite using analytical high resolution transmission electron microscopy

    NASA Astrophysics Data System (ADS)

    French, R. A.; Kim, B.; Murayama, M.; Hochella, M. F.

    2010-12-01

    Schwertmannite, an iron oxyhydroxide sulfate nanomineral, plays a significant role in the geochemistry of acid mine drainage (AMD) as a metastable phase with respect to goethite and by retaining toxic metals, e.g. arsenic [1]. Schwertmannite’s characteristic morphology is needles 100-300 nm long and only 5-10 nm in diameter extending from a dense aggregate. The poorly-and nano-crystalline nature of this mineral requires using high resolution electron microscopy (HRTEM) to be fully characterized. We used HRTEM to identify the polyphasic nature of natural samples of schwertmannite collected from the Iberian Pyrite Belt in Spain. In order to analyze the dense core, samples were prepared in thin section using an ultramicrotome. Data on a sample identified as pure schwertmannite through powder XRD shows the presence of 5-10 nm goethite nanocrystals making up a significant portion of one of the nanoneedle tips (Figure 1). These nanocrystals exhibit lattice fringes and faceted surfaces, both of which match that expected for goethite. The great majority of the nanoneedles are poorly-crystalline (no lattice fringes) with atomically rough surfaces which may be highly active in the uptake of As. The presence of a range of phases and crystallinities in this sample demonstrate incipient stages of the mechanism that results in transformation of schwertmannite to goethite. Further analytical TEM analyses will help us track sorption/desorption, as well as the specific locations of As within these materials upon initial formation, as well as during transformation. [1] Acero et al. (2006) GCA 70, 4130-4139. Figure 1. HRTEM image of 'schwertmannite' nanoneedle with FFT data (inset).

  8. Estimation of Future Return Levels for Heavy Rainfall in the Iberian Peninsula: Comparison of Methodologies

    NASA Astrophysics Data System (ADS)

    Parey, S.

    2014-12-01

    F. J. Acero1, S. Parey2, T.T.H. Hoang2, D. Dacunha-Castelle31Dpto. Física, Universidad de Extremadura, Avda. de Elvas s/n, 06006, Badajoz 2EDF/R&D, 6 quai Watier, 78401 Chatou Cedex, France 3Laboratoire de Mathématiques, Université Paris 11, Orsay, France Trends can already be detected in daily rainfall amount in the Iberian Peninsula (IP), and this will have an impact on the extreme levels. In this study, we compare different ways to estimate future return levels for heavy rainfall, based on the statistical extreme value theory. Both Peaks over Threshold (POT) and block maxima with the Generalized Extreme Value (GEV) distribution will be used and their results compared when linear trends are assumed in the parameters: threshold and scale parameter for POT and location and scale parameter for GEV. But rainfall over the IP is a special variable in that a large number of the values are 0. Thus, the impact of taking this into account is discussed too. Another approach is then tested, based on the evolutions of the mean and variance obtained from the time series of rainy days only, and of the number of rainy days. A statistical test, similar to that designed for temperature in Parey et al. 2013, is used to assess if the trends in extremes can be considered as mostly due to these evolutions when considering only rainy days. The results show that it is mainly the case: the extremes of the residuals, after removing the trends in mean and standard deviation, cannot be differentiated from those of a stationary process. Thus, the future return levels can be estimated from the stationary return level of these residuals and an estimation of the future mean and standard deviation. Moreover, an estimation of the future number of rainy days is used to retrieve the return levels for all days. All of these comparisons are made for an ensemble of high quality rainfall time series observed in the Iberian Peninsula over the period 1961-2010, from which we want to estimate a 20-year

  9. Full mitochondrial genome sequences of two endemic Philippine hornbill species (Aves: Bucerotidae) provide evidence for pervasive mitochondrial DNA recombination

    PubMed Central

    2011-01-01

    Background Although nowaday it is broadly accepted that mitochondrial DNA (mtDNA) may undergo recombination, the frequency of such recombination remains controversial. Its estimation is not straightforward, as recombination under homoplasmy (i.e., among identical mt genomes) is likely to be overlooked. In species with tandem duplications of large mtDNA fragments the detection of recombination can be facilitated, as it can lead to gene conversion among duplicates. Although the mechanisms for concerted evolution in mtDNA are not fully understood yet, recombination rates have been estimated from "one per speciation event" down to 850 years or even "during every replication cycle". Results Here we present the first complete mt genome of the avian family Bucerotidae, i.e., that of two Philippine hornbills, Aceros waldeni and Penelopides panini. The mt genomes are characterized by a tandemly duplicated region encompassing part of cytochrome b, 3 tRNAs, NADH6, and the control region. The duplicated fragments are identical to each other except for a short section in domain I and for the length of repeat motifs in domain III of the control region. Due to the heteroplasmy with regard to the number of these repeat motifs, there is some size variation in both genomes; with around 21,657 bp (A. waldeni) and 22,737 bp (P. panini), they significantly exceed the hitherto longest known avian mt genomes, that of the albatrosses. We discovered concerted evolution between the duplicated fragments within individuals. The existence of differences between individuals in coding genes as well as in the control region, which are maintained between duplicates, indicates that recombination apparently occurs frequently, i.e., in every generation. Conclusions The homogenised duplicates are interspersed by a short fragment which shows no sign of recombination. We hypothesize that this region corresponds to the so-called Replication Fork Barrier (RFB), which has been described from the chicken

  10. Efectos de la irradiación iónica en hielos de moléculas carbonadas

    NASA Astrophysics Data System (ADS)

    Satorre, M. A.

    ónicas. En la mayor parte de los casos las especies producidas por la rotura del enlace, se recombinan volviendo a formar la molécula original. Sin embargo un pequeño porcentaje es capaz de formar nuevas moléculas. Si el ion queda implantado en el hielo y es reactivo (H+, C+,ldots) podría formar parte de una molécula nueva que incorpora un átomo que inicialmente no se encontraba presente en el hielo. También se presentará un contraejemplo para demostrar que no es posible asegurar que siempre que implantemos un ion reactivo, éste formará parte de nuevas moléculas en la mezcla. También se presentará la formación de nuevas moléculas a partir de la irradiación de hielos de metano, que llevan a la formación de otros compuestos como acetileno, eteno, etano,... en los cuales la relación C/H ha variado. Además de estos compuestos se forma también un residuo carbonoso (refractario) que es estable a temperatura ambiente y cuya composición química no es bien conocida. Por último, el aumento de la temperatura de sublimación es también una consecuencia de la irradiación, aunque la magnitud del aumento depende de la mezcla original y de la irradiación sufrida. Existen moléculas que llegan a variar su temperatura de sublimación en decenas de grados. Para el caso de moléculas carbonadas se forman especies por irradiación que son estables a temperatura ambiente. Con todo ello se muestra que los experimentos de laboratorio pueden ayudarnos a comprender la formación, destrucción y variación de las propiedades físicas de los hielos de interés astrofísico con la irradiación.

  11. Estudio de la influencia de la refrigeracion con aire de forma natural e inducida en el comportamiento de instalaciones fotovoltaicas

    NASA Astrophysics Data System (ADS)

    Mazon Hernandez, Rocio

    panels are analysed to compare and select the best configuration. The presented research provides a deep knowledge of how they work as well as information and results for an improvement in future designs of building integrated photovoltaic systems. Este estudio se centra en analizar la influencia negativa de la temperatura en la produccion electrica de paneles fotovoltaicos al estar emplazados sobre cubierta de acero, como sucede en naves industriales y sobre un invernadero. Se estudian diferentes configuraciones que permitan refrigerar los paneles, reduciendo su temperatura y mejorar su rendimiento. Para abordar este problema, se han construido dos instalaciones experimentales, fieles a plantas solares en funcionamiento. Una instalacion engloba dos paneles fotovoltaicos sobre estructura fija al suelo. Uno de los paneles esta integrado sobre una superficie paralela y metalica. Entre ambas superficies existe un espacio que posibilita circular aire, permitiendo refrigerar el panel por conveccion natural, o conveccion forzada impulsando el aire con un ventilador. El otro panel, libre por su cara posterior y se ha considerado de referencia. Se ha estudiado el comportamiento del panel integrado sobre cubierta para diferentes secciones de aire y velocidades inducidas, comparandolo con el panel de referencia. Se ha desarrollado un modelo experimental que nos permite determinar la temperatura del panel en funcion de las variables que influyen en su refrigeracion. Adicionalmente, se han analizado los datos de una planta solar en funcionamiento, con paneles de igual caracteristicas, obteniendo correlaciones entre la temperatura del panel y las variables electricas y comparandolos con las obtenidas en la instalacion experimental. La segunda instalacion experimental reproduce parte de una instalacion solar sobre un invernadero, formada por cuatro paneles fotovoltaicos colocados sobre el plastico del invernadero, existiendo un canal divergente entre ambas superficies. Se estudia la

  12. List of Participants

    NASA Astrophysics Data System (ADS)

    2011-08-01

    GonzalezBUAP, FCFM Lorenzo Díaz CruzBUAP Facultad de Ciencias Físico Matemáticas Luis Rey Díaz BarrónDivisión de Ciencias e Ingenierías Luis UrenaUniversidad de Guanajuato Magda LolaDept. of Physics, University of Patras, Greece Mahmoud WahbaEgyptian Center for Theoretical Physics, MTI Marcus S CohenNew Mexico State University Mario A Acero OrtegaICN - UNAM Mario E GomezUniversidad de Huelva Mark PipeUniversity of Sheffield Mauro NapsucialeDCI-UG Mirco CannoniUniversidad de Huelva Mónica Felipa Ramírez PalaciosUniversidad de Guadalajara Murli Manohar VermaLucknow university, India Nassim BozorgniaUCLA Octavio Obregón Octavio ValenzuelaIA-UNAM Oleg KamaevUniversity of Minnesota Osamu SetoHokkai-Gakuen University Pedro F González DíazIFF, CSIC, Serrano 121, 28006 Madrid, Spain Qaisar ShafiBartol Research Inst. and Delaware U. Raul Hennings-YeomansLos Alamos National Laboratory René Ángeles MartínezDepartamento de Fisica, del DCI de la Universidad de Guanajuato Reyna XoxocotziBUAP, FCFM Rishi Kumar TiwariGovt. Model Science College, Rewa (MP) INDIA Roberto A SussmanICN-UNAM Selim Gómez ÁvilaDCI-UG Sugai KenichiSaitama University Susana Valdez AlvaradoDCI-UG TVladimir - 2K CollaborationColorado State University Tonatiuh MatosCINVESTAV Valeriy DvoeglazovUniversidad de Zacatecas Vannia Gonzalez MaciasDCI-UG Vladimir Avila-ReeseInstituto de Astronomia, UNAM Wolfgang BietenholzINC, UNAM (Mexico) Yamanaka MasatoKyoto Sangyo University Yann MambriniLPT Orsay Yu-Feng ZhouInstitute of Theotretical Physics, Chinese Academy of Sciences, PR China Aaron HigueraDCI-UG Azarael Yebra PérezDCI-UG César Hernández AguayoDCI-UG Jaime Chagoya AlvarezDCI-UG Jonathan Rashid Rosique CampuzanoDCI-UG José Alfredo Soto ÁlvarezDCI-UG Juan Carlos De Haro SantosDCI-UG Luis Eduardo Medina MedranoDCI-UG Maria Fatima Rubio EspinozaDCI-UG Paulo Alberto Rodriguez HerreraDCI-UG Roberto Oziel Gutierrez CotaDCI-UG Rocha Moran Maria PaulinaDCI-UG Xareni Sanchez MonroyDCI-UG

  13. Estudio de la influencia de la refrigeracion con aire de forma natural e inducida en el comportamiento de instalaciones fotovoltaicas

    NASA Astrophysics Data System (ADS)

    Mazon Hernandez, Rocio

    panels are analysed to compare and select the best configuration. The presented research provides a deep knowledge of how they work as well as information and results for an improvement in future designs of building integrated photovoltaic systems. Este estudio se centra en analizar la influencia negativa de la temperatura en la produccion electrica de paneles fotovoltaicos al estar emplazados sobre cubierta de acero, como sucede en naves industriales y sobre un invernadero. Se estudian diferentes configuraciones que permitan refrigerar los paneles, reduciendo su temperatura y mejorar su rendimiento. Para abordar este problema, se han construido dos instalaciones experimentales, fieles a plantas solares en funcionamiento. Una instalacion engloba dos paneles fotovoltaicos sobre estructura fija al suelo. Uno de los paneles esta integrado sobre una superficie paralela y metalica. Entre ambas superficies existe un espacio que posibilita circular aire, permitiendo refrigerar el panel por conveccion natural, o conveccion forzada impulsando el aire con un ventilador. El otro panel, libre por su cara posterior y se ha considerado de referencia. Se ha estudiado el comportamiento del panel integrado sobre cubierta para diferentes secciones de aire y velocidades inducidas, comparandolo con el panel de referencia. Se ha desarrollado un modelo experimental que nos permite determinar la temperatura del panel en funcion de las variables que influyen en su refrigeracion. Adicionalmente, se han analizado los datos de una planta solar en funcionamiento, con paneles de igual caracteristicas, obteniendo correlaciones entre la temperatura del panel y las variables electricas y comparandolos con las obtenidas en la instalacion experimental. La segunda instalacion experimental reproduce parte de una instalacion solar sobre un invernadero, formada por cuatro paneles fotovoltaicos colocados sobre el plastico del invernadero, existiendo un canal divergente entre ambas superficies. Se estudia la