Science.gov

Sample records for achievable depth resolution

  1. Oxygen depth profiling with subnanometre depth resolution

    NASA Astrophysics Data System (ADS)

    Kosmata, Marcel; Munnik, Frans; Hanf, Daniel; Grötzschel, Rainer; Crocoll, Sonja; Möller, Wolfhard

    2014-10-01

    A High-depth Resolution Elastic Recoil Detection (HR-ERD) set-up using a magnetic spectrometer has been taken into operation at the Helmholtz-Zentrum Dresden-Rossendorf for the first time. This instrument allows the investigation of light elements in ultra-thin layers and their interfaces with a depth resolution of less than 1 nm near the surface. As the depth resolution is highly influenced by the experimental measurement parameters, sophisticated optimisation procedures have been implemented. Effects of surface roughness and sample damage caused by high fluences need to be quantified for each kind of material. Also corrections are essential for non-equilibrium charge state distributions that exist very close to the surface. Using the example of a high-k multilayer SiO2/Si3N4Ox/SiO2/Si it is demonstrated that oxygen in ultra-thin films of a few nanometres thickness can be investigated by HR-ERD.

  2. Effect of fundamental depth resolution and cardboard effect to perceived depth resolution on multi-view display.

    PubMed

    Jung, Jae-Hyun; Yeom, Jiwoon; Hong, Jisoo; Hong, Keehoon; Min, Sung-Wook; Lee, Byoungho

    2011-10-10

    In three-dimensional television (3D TV) broadcasting, we find the effect of fundamental depth resolution and the cardboard effect to the perceived depth resolution on multi-view display is important. The observer distance and the specification of multi-view display quantize the expressible depth range, which affect the perception of depth resolution of the observer. In addition, the multi-view 3D TV needs the view synthesis process using depth image-based rendering which induces the cardboard effect from the relation among the stereo pickup, the multi-view synthesis and the multi-view display. In this paper, we analyze the fundamental depth resolution and the cardboard effect from the synthesis process in the multi-view 3D TV broadcasting. After the analysis, the numerical comparison and subjective tests with 20 participants are performed to find the effect of fundamental depth resolution and the cardboard effect to the perceived depth resolution. PMID:21997055

  3. Covering the gap in depth resolution between OCT and SLO in imaging the retina

    NASA Astrophysics Data System (ADS)

    Podoleanu, Adrian Gh.; Rogers, John A.; Suruceanu, Grigore I.; Jackson, David A.

    2001-05-01

    Two instruments are now available for high depth resolution imaging of the retina. A scanning laser ophthalmoscope is a confocal instruments which can achieve no more than 0.3 mm depth resolution. A longitudinal OCT instrument uses a superluminescent diode which determines a depth resolution better than 20 microns. There is a gap in depth resolution between the two technologies. Therefore, different OCT configurations and low coherence sources are investigated to produce a choice of depth resolutions, and to cover the gap between the old confocal technology and the new OCT imaging method. We show that an instrument with adjustable depth resolution is especially useful for the en-face OCT technology. Such an instrument can bring additional benefits to the investigation process, where different requirements must be met. For instance, a poor depth resolution is required in the process of positioning the patient's eye prior to investigation. A good depth resolution is however necessary when imaging small details inside the eye. The utility of the OCT en-face imaging with adjustable coherence length for diagnostic is illustrated by images taken from the eye of a volunteer. Images with a similar aspect to those produced by a scanning laser ophthalmoscope can now be obtained in real time using the OCT principle.

  4. Higher resolution stimulus facilitates depth perception: MT+ plays a significant role in monocular depth perception.

    PubMed

    Tsushima, Yoshiaki; Komine, Kazuteru; Sawahata, Yasuhito; Hiruma, Nobuyuki

    2014-01-01

    Today, we human beings are facing with high-quality virtual world of a completely new nature. For example, we have a digital display consisting of a high enough resolution that we cannot distinguish from the real world. However, little is known how such high-quality representation contributes to the sense of realness, especially to depth perception. What is the neural mechanism of processing such fine but virtual representation? Here, we psychophysically and physiologically examined the relationship between stimulus resolution and depth perception, with using luminance-contrast (shading) as a monocular depth cue. As a result, we found that a higher resolution stimulus facilitates depth perception even when the stimulus resolution difference is undetectable. This finding is against the traditional cognitive hierarchy of visual information processing that visual input is processed continuously in a bottom-up cascade of cortical regions that analyze increasingly complex information such as depth information. In addition, functional magnetic resonance imaging (fMRI) results reveal that the human middle temporal (MT+) plays a significant role in monocular depth perception. These results might provide us with not only the new insight of our neural mechanism of depth perception but also the future progress of our neural system accompanied by state-of- the-art technologies. PMID:25327168

  5. Higher resolution stimulus facilitates depth perception: MT+ plays a significant role in monocular depth perception.

    PubMed

    Tsushima, Yoshiaki; Komine, Kazuteru; Sawahata, Yasuhito; Hiruma, Nobuyuki

    2014-10-20

    Today, we human beings are facing with high-quality virtual world of a completely new nature. For example, we have a digital display consisting of a high enough resolution that we cannot distinguish from the real world. However, little is known how such high-quality representation contributes to the sense of realness, especially to depth perception. What is the neural mechanism of processing such fine but virtual representation? Here, we psychophysically and physiologically examined the relationship between stimulus resolution and depth perception, with using luminance-contrast (shading) as a monocular depth cue. As a result, we found that a higher resolution stimulus facilitates depth perception even when the stimulus resolution difference is undetectable. This finding is against the traditional cognitive hierarchy of visual information processing that visual input is processed continuously in a bottom-up cascade of cortical regions that analyze increasingly complex information such as depth information. In addition, functional magnetic resonance imaging (fMRI) results reveal that the human middle temporal (MT+) plays a significant role in monocular depth perception. These results might provide us with not only the new insight of our neural mechanism of depth perception but also the future progress of our neural system accompanied by state-of- the-art technologies.

  6. High-resolution spectrometer: solution to the axial resolution and ranging depth trade-off of SD-OCT

    NASA Astrophysics Data System (ADS)

    Marvdashti, Tahereh; Lee, Hee Yoon; Ellerbee, Audrey K.

    2013-03-01

    We demonstrate a cross-dispersed spectrometer for Spectral Domain Optical Coherence Tomography (SD-OCT). The resolution of a conventional SD-OCT spectrometer is limited by the available sizes of the linear array detectors. The adverse consequences of this finite resolution is a trade-off between achieving practical field of view (i.e. ranging depth) and maintaining high axial resolution. Inspired by spectrometer designs for astronomy, we take advantage of very high pixel-density 2D CCD arrays to map a single-shot 2D spectrum to an OCT A-scan. The basic system can be implemented using a high-resolution Echelle grating crossed with a prism in a direction orthogonal to the dispersion axis. In this geometry, the interferometric light returning from the OCT system is dispersed in two dimensions; the resulting spectrum can achieve more pixels than a traditional OCT spectrometer (which increases the ranging depth) and maintains impressive axial resolution because of the broad bandwidth of the detected OCT light. To the best of our knowledge, we present the first demonstration of OCT data using an Echelle-based cross-dispersed spectrometer. Potential applications for such a system include high-resolution imaging of the retina or the anterior segment of the eye over extended imaging depths and small animal imaging.

  7. Sampling Depths, Depth Shifts, and Depth Resolutions for Bi(n)(+) Ion Analysis in Argon Gas Cluster Depth Profiles.

    PubMed

    Havelund, R; Seah, M P; Gilmore, I S

    2016-03-10

    Gas cluster sputter depth profiling is increasingly used for the spatially resolved chemical analysis and imaging of organic materials. Here, a study is reported of the sampling depth in secondary ion mass spectrometry depth profiling. It is shown that effects of the sampling depth leads to apparent shifts in depth profiles of Irganox 3114 delta layers in Irganox 1010 sputtered, in the dual beam mode, using 5 keV Ar₂₀₀₀⁺ ions and analyzed with Bi(q+), Bi₃(q+) and Bi₅(q+) ions (q = 1 or 2) with energies between 13 and 50 keV. The profiles show sharp delta layers, broadened from their intrinsic 1 nm thickness to full widths at half-maxima (fwhm's) of 8-12 nm. For different secondary ions, the centroids of the measured delta layers are shifted deeper or shallower by up to 3 nm from the position measured for the large, 564.36 Da (C₃₃H₄₆N₃O₅⁻) characteristic ion for Irganox 3114 used to define a reference position. The shifts are linear with the Bi(n)(q+) beam energy and are greatest for Bi₃(q+), slightly less for Bi₅(q+) with its wider or less deep craters, and significantly less for Bi(q+) where the sputtering yield is very low and the primary ion penetrates more deeply. The shifts increase the fwhm’s of the delta layers in a manner consistent with a linearly falling generation and escape depth distribution function (GEDDF) for the emitted secondary ions, relevant for a paraboloid shaped crater. The total depth of this GEDDF is 3.7 times the delta layer shifts. The greatest effect is for the peaks with the greatest shifts, i.e. Bi₃(q+) at the highest energy, and for the smaller fragments. It is recommended that low energies be used for the analysis beam and that carefully selected, large, secondary ion fragments are used for measuring depth distributions, or that the analysis be made in the single beam mode using the sputtering Ar cluster ions also for analysis. PMID:26883085

  8. Subpixel Resolution In Depth Perceived Via 3-D Television

    NASA Technical Reports Server (NTRS)

    Diner, Daniel B.; Von Sydow, Marika; Fender, Derek H.

    1993-01-01

    Report describes experiment in which two black vertical bars on featureless white background placed near intersection of optical axes of two charge-coupled-device video cameras positioned to give stereoscopic views. Trained human observers found to perceive depths at subpixel resolutions in stereoscopic television images. This finding significant for remote stereoscopic monitoring, expecially during precise maneuvers of remotely controlled manipulators. Also significant for research in processing of visual information by human brain.

  9. The IRAC Lensing Survey: Achieving JWST depth with Spitzer

    NASA Astrophysics Data System (ADS)

    Egami, Eiichi; Ellis, Richard; Fazio, Giovanni; Huang, Jiasheng; Jiang, Linghua; Kneib, Jean-Paul; Pello, Roser; Richard, Johan; Rieke, George; Schaerer, Daniel; Smith, Graham; Stark, Daniel; Werner, Mike

    2008-12-01

    Massive clusters of galaxies are now recognized as very effective 'cosmic telescopes'. Because of the gravitational lensing effect, they can amplify significantly the background sources - by factors of a few tens - thereby bringing into view faint sources that would otherwise be unobservable. Note that in the background-limited case, which is applicable to IRAC observations, a factor of 20-30 gravitational amplification translates into increasing the integration time by a factor of 400-900. Because of this tremendous gain in sensitivity, IRAC imaging of lensing clusters will allow us to achieve JWST depth (~10 nJy) with Spitzer. Despite this great possibility, however, the full potential of the lensing cluster technique has not yet been realized due to the small number of clusters that have well-constrained accurate mass models. Here, we propose to conduct an IRAC imaging survey of 47 massive lensing clusters (5 hours/band, 2 bands) for which we have constructed accurate mass models through many years of intensive imaging/spectroscopic campaigns with HST, Keck, and VLT telescopes. This is the first time when such a large, statistical sample of clusters will be systematically employed to probe high-redshift Universe, and this proposed IRAC survey is a key component of our comprehensive program, which includes HST/WFC3 and Herschel observations starting next year. Scientifically, we will use the obtained IRAC data to (1) characterize z>6 galaxies (expecting ~50 z~7-8 galaxy detections), (2) support future Herschel and ALMA surveys, and (3) search for z>6 supernovae. The resultant data set will be a great legacy of Spitzer, allowing us to start tackling JWST sciences well before its launch.

  10. RBS with high depth resolution using small magnetic spectrometers

    NASA Astrophysics Data System (ADS)

    Grötzschel, Rainer; Klein, Christoph; Mäder, Michael

    2004-06-01

    The increasing importance of ultra-thin layers for novel technologies demands quantitative analysis techniques with a depth resolution of atomic monolayers, which can be obtained for RBS and ERDA by magnetic spectrometers. We operate at the 3 MV Tandetron accelerator a magnetic spectrometer consisting of an UHV scattering chamber and a simple dipole magnet with circular field boundaries (Browne-Buechner spectrometer). Since in many cases of high resolution ion beam analysis the samples must be prepared in situ in UHV, the chamber with a base vacuum of 4 × 10 -10 mbar is equipped with an ion sputter gun and two low rate e-beam evaporators for in situ layer deposition. A RHEED system is used to check the surface reconstruction and monitor the layer growth. Samples are transferred, together with a BN heater, to the precision 5-axes channelling goniometer. The magnet with a mean radius of 0.65 m is mounted vertically and can be positioned either at 35.5° or 144.5°. The backward position offers the advantage of a high mass resolution, but the Rutherford cross sections are a factor of about 100 lower than at the forward angle, which is the preferred position if kinematically possible. At the 5 MV tandem accelerator a QQDS magnetic spectrometer is being installed. The facilities for in situ sample preparation in UHV are similar. These spectrometers are described in detail and recent applications are discussed.

  11. Wavefront engineering: selective aperture illumination for increased depth of focus and super-resolution for photolithography

    NASA Astrophysics Data System (ADS)

    Kant, Rishi

    2015-08-01

    Photolithography has been and is the driving force behind enhancement and miniaturization of computers and their peripherals. Advances in photolithographic processes have enabled modern integrated circuits to have millions of electrical devices on a single, small circuit chip. Diffraction optics plays a central role in the photolithographic process, as during etching, the incoming light passes through a moderate-aperture focusing lens and converges on every point on the chip. Thus, the structure of the electromagnetic field in the focal region is of considerable interest. While techniques such as implantation and deposition processes control the vertical architecture of the integrated circuit chip, the lateral dimensions are defined solely by diffraction optics. The conventional imaging approach has a severe restriction because depth of focus shortens with an increase in resolution. Even though using shorter wavelength light such as deep ultraviolet is helpful, it too is reaching a point where further increase in resolution is necessary while, at the same time, preserving or increasing the depth of focus. Shortening of depth of focus with increase resolution is nonetheless the most severe limitation of photolithography. Thus, reduction in wavelength and increase in numerical aperture are viable options, but this approach has tremendous difficulties. In this study, we present a novel approach to achieve both super-resolution and increased depth of focus through a technique called selective aperture illumination (SAI). In SAI, the incoming light is redistributed by means of an optical element, phase, and attenuation masks. It is shown that both the increased depth focus and super-resolution are achieved by selectively choosing appropriate phase and amplitude at the entrance pupil.

  12. Investigation of interdiffusion and depth resolution in Cu/Ni multilayers by means of AES depth profiling

    NASA Astrophysics Data System (ADS)

    Yan, X. L.; Liu, Y.; Swart, H. C.; Wang, J. Y.; Terblans, J. J.

    2016-02-01

    The interdiffusion upon annealing Cu/Ni multilayers structures at 325 °C, 350 °C and 375 °C for 30 min were investigated by Auger electron spectroscopy (AES) depth profiling. The Cu/Ni multilayers structures were deposited on a SiO2 substrate by means of electron beam evaporation in a high vacuum. The measured AES depth profiles of the as-deposited and annealed samples were quantitatively fitted by the Mixing-Roughness-Information depth model assuming that the roughness parameter has linearly increased with the sputtered depth. The roughness values extracted from the depth profiling data fits agreed well with those measured by atomic force microscopy. The depth-dependent interdiffusion coefficients of the annealed samples and depth resolution upon depth profiling of the as-deposited sample were quantitatively evaluated accordingly.

  13. Undetectable Changes in Image Resolution of Luminance-Contrast Gradients Affect Depth Perception

    PubMed Central

    Tsushima, Yoshiaki; Komine, Kazuteru; Sawahata, Yasuhito; Morita, Toshiya

    2016-01-01

    A great number of studies have suggested a variety of ways to get depth information from two dimensional images such as binocular disparity, shape-from-shading, size gradient/foreshortening, aerial perspective, and so on. Are there any other new factors affecting depth perception? A recent psychophysical study has investigated the correlation between image resolution and depth sensation of Cylinder images (A rectangle contains gradual luminance-contrast changes.). It was reported that higher resolution images facilitate depth perception. However, it is still not clear whether or not the finding generalizes to other kinds of visual stimuli, because there are more appropriate visual stimuli for exploration of depth perception of luminance-contrast changes, such as Gabor patch. Here, we further examined the relationship between image resolution and depth perception by conducting a series of psychophysical experiments with not only Cylinders but also Gabor patches having smoother luminance-contrast gradients. As a result, higher resolution images produced stronger depth sensation with both images. This finding suggests that image resolution affects depth perception of simple luminance-contrast differences (Gabor patch) as well as shape-from-shading (Cylinder). In addition, this phenomenon was found even when the resolution difference was undetectable. This indicates the existence of consciously available and unavailable information in our visual system. These findings further support the view that image resolution is a cue for depth perception that was previously ignored. It partially explains the unparalleled viewing experience of novel high resolution displays. PMID:26941693

  14. Undetectable Changes in Image Resolution of Luminance-Contrast Gradients Affect Depth Perception.

    PubMed

    Tsushima, Yoshiaki; Komine, Kazuteru; Sawahata, Yasuhito; Morita, Toshiya

    2016-01-01

    A great number of studies have suggested a variety of ways to get depth information from two dimensional images such as binocular disparity, shape-from-shading, size gradient/foreshortening, aerial perspective, and so on. Are there any other new factors affecting depth perception? A recent psychophysical study has investigated the correlation between image resolution and depth sensation of Cylinder images (A rectangle contains gradual luminance-contrast changes.). It was reported that higher resolution images facilitate depth perception. However, it is still not clear whether or not the finding generalizes to other kinds of visual stimuli, because there are more appropriate visual stimuli for exploration of depth perception of luminance-contrast changes, such as Gabor patch. Here, we further examined the relationship between image resolution and depth perception by conducting a series of psychophysical experiments with not only Cylinders but also Gabor patches having smoother luminance-contrast gradients. As a result, higher resolution images produced stronger depth sensation with both images. This finding suggests that image resolution affects depth perception of simple luminance-contrast differences (Gabor patch) as well as shape-from-shading (Cylinder). In addition, this phenomenon was found even when the resolution difference was undetectable. This indicates the existence of consciously available and unavailable information in our visual system. These findings further support the view that image resolution is a cue for depth perception that was previously ignored. It partially explains the unparalleled viewing experience of novel high resolution displays.

  15. Using ultrahigh sensitive optical microangiography to achieve comprehensive depth resolved microvasculature mapping for human retina

    NASA Astrophysics Data System (ADS)

    An, Lin; Shen, Tueng T.; Wang, Ruikang K.

    2011-10-01

    This paper presents comprehensive and depth-resolved retinal microvasculature images within human retina achieved by a newly developed ultrahigh sensitive optical microangiography (UHS-OMAG) system. Due to its high flow sensitivity, UHS-OMAG is much more sensitive to tissue motion due to the involuntary movement of the human eye and head compared to the traditional OMAG system. To mitigate these motion artifacts on final imaging results, we propose a new phase compensation algorithm in which the traditional phase-compensation algorithm is repeatedly used to efficiently minimize the motion artifacts. Comparatively, this new algorithm demonstrates at least 8 to 25 times higher motion tolerability, critical for the UHS-OMAG system to achieve retinal microvasculature images with high quality. Furthermore, the new UHS-OMAG system employs a high speed line scan CMOS camera (240 kHz A-line scan rate) to capture 500 A-lines for one B-frame at a 400 Hz frame rate. With this system, we performed a series of in vivo experiments to visualize the retinal microvasculature in humans. Two featured imaging protocols are utilized. The first is of the low lateral resolution (16 μm) and a wide field of view (4 × 3 mm2 with single scan and 7 × 8 mm2 for multiple scans), while the second is of the high lateral resolution (5 μm) and a narrow field of view (1.5 × 1.2 mm2 with single scan). The great imaging performance delivered by our system suggests that UHS-OMAG can be a promising noninvasive alternative to the current clinical retinal microvasculature imaging techniques for the diagnosis of eye diseases with significant vascular involvement, such as diabetic retinopathy and age-related macular degeneration.

  16. Achieving High Resolution Timer Events in Virtualized Environment

    PubMed Central

    Adamczyk, Blazej; Chydzinski, Andrzej

    2015-01-01

    Virtual Machine Monitors (VMM) have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs—Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service). Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events. PMID:26177366

  17. Achieving High Resolution Timer Events in Virtualized Environment.

    PubMed

    Adamczyk, Blazej; Chydzinski, Andrzej

    2015-01-01

    Virtual Machine Monitors (VMM) have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service). Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events. PMID:26177366

  18. Wavelength Shifting Phoswich Detectors for Superior Depth-of-Interaction Resolution

    SciTech Connect

    Melcher, Charles L; Eriksson, Lars

    2012-10-25

    In order to simultaneously achieve both high spatial resolution and high sensitivity in small Positron Emission Tomography (PET) systems, scintillation detectors must be long in the radial direction as well as able to provide depth-of-interaction (DOI) information. DOI information is typically provided by constructing detectors from two or more layers of scintillators that are identifiable due to their different decay times. This approach has worked well in tomographs such as the High Resolution Research Tomograph (HRRT, CTI PET Systems, Inc.) in which the emission and excitation bands of the scintillator layers do not overlap each other. However, many potentially important pairs of scintillator crystals exist in which the emission of one crystal is, in fact, absorbed and re-emitted by the second crystal, thus impacting the pulse shape discrimination process used to identify the scintillator layers. These potentially useful pairs of scintillators are unlikely to be implemented in phoswich detectors without a comprehensive understanding of the complex emission that results when the light of one crystal is absorbed by the second crystal and then reemitted. Our objective is to develop a fundamental understanding of the optical phenomena that occur in phoswich detectors and to exploit these phenomena to achieve improved spatial resolution in small high sensitivity PET scanners.

  19. Two-photon instant structured illumination microscopy improves the depth penetration of super-resolution imaging in thick scattering samples.

    PubMed

    Winter, Peter W; York, Andrew G; Nogare, Damian Dalle; Ingaramo, Maria; Christensen, Ryan; Chitnis, Ajay; Patterson, George H; Shroff, Hari

    2014-09-20

    Fluorescence imaging methods that achieve spatial resolution beyond the diffraction limit (super-resolution) are of great interest in biology. We describe a super-resolution method that combines two-photon excitation with structured illumination microscopy (SIM), enabling three-dimensional interrogation of live organisms with ~150 nm lateral and ~400 nm axial resolution, at frame rates of ~1 Hz. By performing optical rather than digital processing operations to improve resolution, our microscope permits super-resolution imaging with no additional cost in acquisition time or phototoxicity relative to the point-scanning two-photon microscope upon which it is based. Our method provides better depth penetration and inherent optical sectioning than all previously reported super-resolution SIM implementations, enabling super-resolution imaging at depths exceeding 100 μm from the coverslip surface. The capability of our system for interrogating thick live specimens at high resolution is demonstrated by imaging whole nematode embryos and larvae, and tissues and organs inside zebrafish embryos.

  20. Two-photon instant structured illumination microscopy improves the depth penetration of super-resolution imaging in thick scattering samples

    PubMed Central

    Winter, Peter W.; York, Andrew G.; Nogare, Damian Dalle; Ingaramo, Maria; Christensen, Ryan; Chitnis, Ajay; Patterson, George H.; Shroff, Hari

    2014-01-01

    Fluorescence imaging methods that achieve spatial resolution beyond the diffraction limit (super-resolution) are of great interest in biology. We describe a super-resolution method that combines two-photon excitation with structured illumination microscopy (SIM), enabling three-dimensional interrogation of live organisms with ~150 nm lateral and ~400 nm axial resolution, at frame rates of ~1 Hz. By performing optical rather than digital processing operations to improve resolution, our microscope permits super-resolution imaging with no additional cost in acquisition time or phototoxicity relative to the point-scanning two-photon microscope upon which it is based. Our method provides better depth penetration and inherent optical sectioning than all previously reported super-resolution SIM implementations, enabling super-resolution imaging at depths exceeding 100 μm from the coverslip surface. The capability of our system for interrogating thick live specimens at high resolution is demonstrated by imaging whole nematode embryos and larvae, and tissues and organs inside zebrafish embryos. PMID:25485291

  1. High resolution depth-resolved imaging from multi-focal images for medical ultrasound.

    PubMed

    Diamantis, Konstantinos; Dalgarno, Paul A; Greenaway, Alan H; Anderson, Tom; Jensen, Jørgen Arendt; Sboros, Vassilis

    2015-01-01

    An ultrasound imaging technique providing sub-diffraction limit axial resolution for point sources is proposed. It is based on simultaneously acquired multi-focal images of the same object, and on the image metric of sharpness. The sharpness is extracted by image data and presents higher values for in-focus images. The technique is derived from biological microscopy and is validated here with simulated ultrasound data. A linear array probe is used to scan a point scatterer phantom that moves in depth with a controlled step. From the beamformed responses of each scatterer position the image sharpness is assessed. Values from all positions plotted together form a curve that peaks at the receive focus, which is set during the beamforming. Selection of three different receive foci for each acquired dataset will result in the generation of three overlapping sharpness curves. A set of three calibration curves combined with the use of a maximum-likelihood algorithm is then able to estimate, with high precision, the depth location of any emitter fron each single image. Estimated values are compared with the ground truth demonstrating that an accuracy of 28.6 μm (0.13λ) is achieved for a 4 mm depth range. PMID:26737920

  2. Inference of mantle viscosity for depth resolutions of GIA observations

    NASA Astrophysics Data System (ADS)

    Nakada, Masao; Okuno, Jun'ichi

    2016-11-01

    Inference of the mantle viscosity from observations for glacial isostatic adjustment (GIA) process has usually been conducted through the analyses based on the simple three-layer viscosity model characterized by lithospheric thickness, upper- and lower-mantle viscosities. Here, we examine the viscosity structures for the simple three-layer viscosity model and also for the two-layer lower-mantle viscosity model defined by viscosities of η670,D (670-D km depth) and ηD,2891 (D-2891 km depth) with D-values of 1191, 1691 and 2191 km. The upper-mantle rheological parameters for the two-layer lower-mantle viscosity model are the same as those for the simple three-layer one. For the simple three-layer viscosity model, rate of change of degree-two zonal harmonics of geopotential due to GIA process (GIA-induced J˙2) of -(6.0-6.5) × 10-11 yr-1 provides two permissible viscosity solutions for the lower mantle, (7-20) × 1021 and (5-9) × 1022 Pa s, and the analyses with observational constraints of the J˙2 and Last Glacial Maximum (LGM) sea levels at Barbados and Bonaparte Gulf indicate (5-9) × 1022 Pa s for the lower mantle. However, the analyses for the J˙2 based on the two-layer lower-mantle viscosity model only require a viscosity layer higher than (5-10) × 1021 Pa s for a depth above the core-mantle boundary (CMB), in which the value of (5-10) × 1021 Pa s corresponds to the solution of (7-20) × 1021 Pa s for the simple three-layer one. Moreover, the analyses with the J˙2 and LGM sea level constraints for the two-layer lower-mantle viscosity model indicate two viscosity solutions: η670,1191 > 3 × 1021 and η1191,2891 ˜ (5-10) × 1022 Pa s, and η670,1691 > 1022 and η1691,2891 ˜ (5-10) × 1022 Pa s. The inferred upper-mantle viscosity for such solutions is (1-4) × 1020 Pa s similar to the estimate for the simple three-layer viscosity model. That is, these analyses require a high viscosity layer of (5-10) × 1022 Pa s at least in the deep mantle, and suggest

  3. Comparison of curricular breadth, depth, and recurrence and physics achievement of TIMSS Population 3 countries

    NASA Astrophysics Data System (ADS)

    Murdock, John

    This study is a secondary analysis of data from the 1995 administration of the Third International Mathematics and Science Study (TIMSS). The purpose is to compare breadth, depth, and recurrence of the typical physics curriculum in the United States with the typical curricula in different countries and to determine if there are associations between these three curricular constructs and physics achievement. The first data analysis consisted of descriptive statistics (means, standard deviations, and standardized scores) for each of the three curricular variables. This analysis was used to compare the curricular profile in physics of the United States with the profiles of the other countries in the sample. The second data analysis consisted of six sets of correlations relating the three curricular variables with achievement. Five of the correlations were for the five physics content areas and the sixth was for all of physics. This analysis was used to determine if any associations exist between the three curricular constructs and achievement. The results show that the U.S. curriculum has low breadth, low depth, and high recurrence. The U.S. curricular profile was also found to be unique when compared with the profiles of the other countries in the sample. The only statistically significant correlation is between achievement and depth in a positive direction. The correlations between breadth and achievement and between recurrence and achievement were both not statistically significant. Based on the results of this study, depth of curriculum is the only curricular variable that is closely related to physics achievement for the TIMSS sample. Recurrence of curriculum is not related to physics achievement in TIMSS Population 3 countries. The results show no relationship between breadth and achievement, but the physics topics in the TIMSS content framework do not give a complete picture of breadth of physics curriculum in the participating countries. The unique curricular

  4. Convective gas flow development and the maximum depths achieved by helophyte vegetation in lakes

    PubMed Central

    Sorrell, Brian K.; Hawes, Ian

    2010-01-01

    Background and Aims Convective gas flow in helophytes (emergent aquatic plants) is thought to be an important adaptation for the ability to colonize deep water. In this study, the maximum depths achieved by seven helophytes were compared in 17 lakes differing in nutrient enrichment, light attenuation, shoreline exposure and sediment characteristics to establish the importance of convective flow for their ability to form the deepest helophyte vegetation in different environments. Methods Convective gas flow development was compared amongst the seven species, and species were allocated to ‘flow absent’, ‘low flow’ and ‘high flow’ categories. Regression tree analysis and quantile regression analysis were used to determine the roles of flow category, lake water quality, light attenuation and shoreline exposure on maximum helophyte depths. Key Results Two ‘flow absent’ species were restricted to very shallow water in all lakes and their depths were not affected by any environmental parameters. Three ‘low flow’ and two ‘high flow’ species had wide depth ranges, but ‘high flow’ species formed the deepest vegetation far more frequently than ‘low flow’ species. The ‘low flow’ species formed the deepest vegetation most commonly in oligotrophic lakes where oxygen demands in sediments were low, especially on exposed shorelines. The ‘high flow’ species were almost always those forming the deepest vegetation in eutrophic lakes, with Eleocharis sphacelata predominant when light attenuation was low, and Typha orientalis when light attenuation was high. Depths achieved by all five species with convective flow were limited by shoreline exposure, but T. orientalis was the least exposure-sensitive species. Conclusions Development of convective flow appears to be essential for dominance of helophyte species in >0·5 m depth, especially under eutrophic conditions. Exposure, sediment characteristics and light attenuation frequently constrain them

  5. Depth

    PubMed Central

    Koenderink, Jan J; van Doorn, Andrea J; Wagemans, Johan

    2011-01-01

    Depth is the feeling of remoteness, or separateness, that accompanies awareness in human modalities like vision and audition. In specific cases depths can be graded on an ordinal scale, or even measured quantitatively on an interval scale. In the case of pictorial vision this is complicated by the fact that human observers often appear to apply mental transformations that involve depths in distinct visual directions. This implies that a comparison of empirically determined depths between observers involves pictorial space as an integral entity, whereas comparing pictorial depths as such is meaningless. We describe the formal structure of pictorial space purely in the phenomenological domain, without taking recourse to the theories of optics which properly apply to physical space—a distinct ontological domain. We introduce a number of general ways to design and implement methods of geodesy in pictorial space, and discuss some basic problems associated with such measurements. We deal mainly with conceptual issues. PMID:23145244

  6. Depth.

    PubMed

    Koenderink, Jan J; van Doorn, Andrea J; Wagemans, Johan

    2011-01-01

    Depth is the feeling of remoteness, or separateness, that accompanies awareness in human modalities like vision and audition. In specific cases depths can be graded on an ordinal scale, or even measured quantitatively on an interval scale. In the case of pictorial vision this is complicated by the fact that human observers often appear to apply mental transformations that involve depths in distinct visual directions. This implies that a comparison of empirically determined depths between observers involves pictorial space as an integral entity, whereas comparing pictorial depths as such is meaningless. We describe the formal structure of pictorial space purely in the phenomenological domain, without taking recourse to the theories of optics which properly apply to physical space-a distinct ontological domain. We introduce a number of general ways to design and implement methods of geodesy in pictorial space, and discuss some basic problems associated with such measurements. We deal mainly with conceptual issues.

  7. Depth resolution, angle dependence, and the sputtering yield of Irganox 1010 by coronene primary ions.

    PubMed

    Seah, Martin P; Spencer, Steve J; Shard, Alex G

    2013-10-01

    A study is reported of the depth resolution and angle dependence of sputtering yields using the reference organic material, Irganox 1010, for a new coronene(+) depth profiling ion source at 8 and 16 keV beam energies. This source provides excellent depth profiles as shown by 8.5 nm marker layers of Irganox 3114. Damage occurs but may be ignored for angles of incidence above 70° from the surface normal, as shown by X-ray photoelectron spectroscopy (XPS) of the C 1s peak structure. Above 70°, XPS profiles of excellent depth resolution are obtained. The depth resolution, after removal of the thickness of the delta layers, shows a basic contribution of 5.7 nm together with a contribution of 0.043 times the depth sputtered. This is lower than generally reported for cluster sources. The coronene(+) source is thus found to be a useful and practical source for depth profiling organic materials. The angle dependencies of both the undamaged and damaged materials are described by a simple equation. The sputtering yields for the undamaged material are described by a universal equation and are consistent with those obtained for C60(+) sputtering. Comparison with the sputtering yields using an argon gas cluster ion source shows great similarities, but the yields for both the coronene(+) and C60(+) primary ion sources are slightly lower.

  8. Accuracy and Resolution of Kinect Depth Data for Indoor Mapping Applications

    PubMed Central

    Khoshelham, Kourosh; Elberink, Sander Oude

    2012-01-01

    Consumer-grade range cameras such as the Kinect sensor have the potential to be used in mapping applications where accuracy requirements are less strict. To realize this potential insight into the geometric quality of the data acquired by the sensor is essential. In this paper we discuss the calibration of the Kinect sensor, and provide an analysis of the accuracy and resolution of its depth data. Based on a mathematical model of depth measurement from disparity a theoretical error analysis is presented, which provides an insight into the factors influencing the accuracy of the data. Experimental results show that the random error of depth measurement increases with increasing distance to the sensor, and ranges from a few millimeters up to about 4 cm at the maximum range of the sensor. The quality of the data is also found to be influenced by the low resolution of the depth measurements. PMID:22438718

  9. Television monitor field shifter and an opto-electronic method for obtaining a stereo image of optimal depth resolution and reduced depth distortion on a single screen

    NASA Technical Reports Server (NTRS)

    Diner, Daniel B. (Inventor)

    1989-01-01

    A method and apparatus is developed for obtaining a stereo image with reduced depth distortion and optimum depth resolution. Static and dynamic depth distortion and depth resolution tradeoff is provided. Cameras obtaining the images for a stereo view are converged at a convergence point behind the object to be presented in the image, and the collection-surface-to-object distance, the camera separation distance, and the focal lengths of zoom lenses for the cameras are all increased. Doubling the distances cuts the static depth distortion in half while maintaining image size and depth resolution. Dynamic depth distortion is minimized by panning a stereo view-collecting camera system about a circle which passes through the convergence point and the camera's first nodal points. Horizontal field shifting of the television fields on a television monitor brings both the monitor and the stereo views within the viewer's limit of binocular fusion.

  10. High resolution TOF - SIMS depth profiling of nano-film multilayers

    SciTech Connect

    Bhushan, K. G.; Mukundhan, R.; Gupta, S. K.

    2013-02-05

    We present the results of depth profiling studies conducted using an indigenously developed dual-beam high resolution Time-of-Flight Secondary Ion Mass Spectrometer (TOF-SIMS) on thinfilm W-C-W multilayer structure grown on Si substrate. Opto 8 layers could be clearly identified. Mixing of layers is seen which from analysis using roughness model calculations indicate a mixing thickness of about 2nm that correspond to the escape depth of secondary ions from the sample.

  11. Evaluation of the variable depth resolution of active dynamic thermography on human skin

    NASA Astrophysics Data System (ADS)

    Prindeze, Nicholas J.; Hoffman, Hilary A.; Carney, Bonnie C.; Moffatt, Lauren T.; Loew, Murray H.; Shupp, Jeffrey W.

    2015-06-01

    Active dynamic thermography (ADT) is an imaging technique capable of characterizing the non-homogenous thermal conductance of damaged tissues. The purpose of this study was to determine optimal stimulation parameters and quantify the optical resolution of ADT through various depths of human skin. Excised tissue from plastic surgery operations was collected immediately following excision. A total of 12 thin to thick split-thickness grafts were harvested from 3 patients. Grafts were placed on top of a 3D printed resolution chart and thermal stimulation was applied from a 300W halogen lamp array for between 0.5-10 seconds to determine optimal parameters. Video was captured with a thermal camera, and analysis was performed by reconstructing an image from thermal gradients. In this study ADT resolved 0.445+/-0 lp/mm at a depth of 0.010", 0.356+/-0.048 lp/mm at a depth of 0.015", 0.334+/-0.027 lp/mm at a depth of 0.020" and 0.265+/-0.022 lp/mm at a depth of 0.025". The stimulus energy required for maximum resolution at each depth was 3- 4s, 8s, 12s and 12s respectively. ADT is a sensitive technique for imaging dermal structure, capable of resolving detail as fine as 1124 μm, 1427 μm, 1502 μm and 1893 μm in thin to thick split-thickness skin grafts respectively. This study has characterized a correlation between stimulus input and maximal resolution at differing depths of skin. It has also defined the functional imaging depth of ADT to below the sub-cutis, well below conventional spectrophotometric techniques.

  12. Improving Resolution and Depth of Astronomical Observations via Modern Mathematical Methods for Image Analysis

    NASA Astrophysics Data System (ADS)

    Castellano, M.; Ottaviani, D.; Fontana, A.; Merlin, E.; Pilo, S.; Falcone, M.

    2015-09-01

    In the past years modern mathematical methods for image analysis have led to a revolution in many fields, from computer vision to scientific imaging. However, some recently developed image processing techniques successfully exploited by other sectors have been rarely, if ever, experimented on astronomical observations. We present here tests of two classes of variational image enhancement techniques: "structure-texture decomposition" and "super-resolution" showing that they are effective in improving the quality of observations. Structure-texture decomposition allows to recover faint sources previously hidden by the background noise, effectively increasing the depth of available observations. Super-resolution yields an higher-resolution and a better sampled image out of a set of low resolution frames, thus mitigating problematics in data analysis arising from the difference in resolution/sampling between different instruments, as in the case of EUCLID VIS and NIR imagers.

  13. Three-dimensional range-gated imaging at infrared wavelengths with super-resolution depth mapping

    NASA Astrophysics Data System (ADS)

    Laurenzis, Martin; Christnacher, Frank; Metzger, Nicolas; Bacher, Emmanuel; Zielenski, Ingo

    2009-05-01

    Range-gated viewing is a prominent technique for night vision, remote sensing and vision trough obstacles (fog, smoke, camouflage netting ). Furthermore, range-gated images reflect not only the scene reflectance but also contain depth information. The whole depth information can be calculated from a minimum number of two range-gated images via the super-resolution depth mapping technique. For the first time, this method is applied to range-gated viewing at infrared wavelengths. An EBCMOS camera and a solid sate laser illumination in the 1.5 μm wavelength scale were used to depth-map a scene with minimal laser activity of 9 ns per image.

  14. Improving depth resolution in digital breast tomosynthesis by iterative image reconstruction

    NASA Astrophysics Data System (ADS)

    Roth, Erin G.; Kraemer, David N.; Sidky, Emil Y.; Reiser, Ingrid S.; Pan, Xiaochuan

    2015-03-01

    Digital breast tomosynthesis (DBT) is currently enjoying tremendous growth in its application to screening for breast cancer. This is because it addresses a major weakness of mammographic projection imaging; namely, a cancer can be hidden by overlapping fibroglandular tissue structures or the same normal structures can mimic a malignant mass. DBT addresses these issues by acquiring few projections over a limited angle scanning arc that provides some depth resolution. As DBT is a relatively new device, there is potential to improve its performance significantly with improved image reconstruction algorithms. Previously, we reported a variation of adaptive steepest descent - projection onto convex sets (ASD-POCS) for DBT, which employed a finite differencing filter to enhance edges for improving visibility of tissue structures and to allow for volume-of-interest reconstruction. In the present work we present a singular value decomposition (SVD) analysis to demonstrate the gain in depth resolution for DBT afforded by use of the finite differencing filter.

  15. Depth Filters Containing Diatomite Achieve More Efficient Particle Retention than Filters Solely Containing Cellulose Fibers

    PubMed Central

    Buyel, Johannes F.; Gruchow, Hannah M.; Fischer, Rainer

    2015-01-01

    The clarification of biological feed stocks during the production of biopharmaceutical proteins is challenging when large quantities of particles must be removed, e.g., when processing crude plant extracts. Single-use depth filters are often preferred for clarification because they are simple to integrate and have a good safety profile. However, the combination of filter layers must be optimized in terms of nominal retention ratings to account for the unique particle size distribution in each feed stock. We have recently shown that predictive models can facilitate filter screening and the selection of appropriate filter layers. Here we expand our previous study by testing several filters with different retention ratings. The filters typically contain diatomite to facilitate the removal of fine particles. However, diatomite can interfere with the recovery of large biopharmaceutical molecules such as virus-like particles and aggregated proteins. Therefore, we also tested filtration devices composed solely of cellulose fibers and cohesive resin. The capacities of both filter types varied from 10 to 50 L m−2 when challenged with tobacco leaf extracts, but the filtrate turbidity was ~500-fold lower (~3.5 NTU) when diatomite filters were used. We also tested pre–coat filtration with dispersed diatomite, which achieved capacities of up to 120 L m−2 with turbidities of ~100 NTU using bulk plant extracts, and in contrast to the other depth filters did not require an upstream bag filter. Single pre-coat filtration devices can thus replace combinations of bag and depth filters to simplify the processing of plant extracts, potentially saving on time, labor and consumables. The protein concentrations of TSP, DsRed and antibody 2G12 were not affected by pre-coat filtration, indicating its general applicability during the manufacture of plant-derived biopharmaceutical proteins. PMID:26734037

  16. Depth Filters Containing Diatomite Achieve More Efficient Particle Retention than Filters Solely Containing Cellulose Fibers.

    PubMed

    Buyel, Johannes F; Gruchow, Hannah M; Fischer, Rainer

    2015-01-01

    The clarification of biological feed stocks during the production of biopharmaceutical proteins is challenging when large quantities of particles must be removed, e.g., when processing crude plant extracts. Single-use depth filters are often preferred for clarification because they are simple to integrate and have a good safety profile. However, the combination of filter layers must be optimized in terms of nominal retention ratings to account for the unique particle size distribution in each feed stock. We have recently shown that predictive models can facilitate filter screening and the selection of appropriate filter layers. Here we expand our previous study by testing several filters with different retention ratings. The filters typically contain diatomite to facilitate the removal of fine particles. However, diatomite can interfere with the recovery of large biopharmaceutical molecules such as virus-like particles and aggregated proteins. Therefore, we also tested filtration devices composed solely of cellulose fibers and cohesive resin. The capacities of both filter types varied from 10 to 50 L m(-2) when challenged with tobacco leaf extracts, but the filtrate turbidity was ~500-fold lower (~3.5 NTU) when diatomite filters were used. We also tested pre-coat filtration with dispersed diatomite, which achieved capacities of up to 120 L m(-2) with turbidities of ~100 NTU using bulk plant extracts, and in contrast to the other depth filters did not require an upstream bag filter. Single pre-coat filtration devices can thus replace combinations of bag and depth filters to simplify the processing of plant extracts, potentially saving on time, labor and consumables. The protein concentrations of TSP, DsRed and antibody 2G12 were not affected by pre-coat filtration, indicating its general applicability during the manufacture of plant-derived biopharmaceutical proteins.

  17. Scanning holographic microscopy with transverse resolution exceeding the Rayleigh limit and extended depth of focus

    PubMed Central

    El Maghnouji, Alouahab; Foster, Richard

    2005-01-01

    We demonstrate experimentally that the method of scanning holographic microscopy is capable of producing images reconstructed numerically from holograms recorded digitally in the time domain by scanning, with transverse and axial resolutions comparable to those of wide-field or scanning microscopy with the same objective. Furthermore, we show that it is possible to synthesize the point-spread function of scanning holographic microscopy to obtain, with the same objective, holographic reconstructions with a transverse resolution exceeding the Rayleigh limit of the objective up to a factor of 2 in the limit of low numerical aperture. These holographic reconstructions also exhibit an extended depth of focus, the extent of which is adjustable without compromising the transverse resolution. PMID:15898548

  18. Spatio-temporal evaluation of resolution enhancement for passive microwave soil moisture and vegetation optical depth

    NASA Astrophysics Data System (ADS)

    Gevaert, A. I.; Parinussa, R. M.; Renzullo, L. J.; van Dijk, A. I. J. M.; de Jeu, R. A. M.

    2016-03-01

    Space-borne passive microwave radiometers are used to derive land surface parameters such as surface soil moisture and vegetation optical depth (VOD). However, the value of such products in regional hydrology is limited by their coarse resolution. In this study, the land parameter retrieval model (LPRM) is used to derive enhanced resolution (∼10 km) soil moisture and VOD from advanced microwave scanning radiometer (AMSR-E) brightness temperatures sharpened by a modulation technique based on high-frequency observations. A precipitation mask based on brightness temperatures was applied to remove precipitation artefacts in the sharpened LPRM products. The spatial and temporal patterns in the resulting products are evaluated against field-measured and modeled soil moisture as well as the normalized difference vegetation index (NDVI) over mainland Australia. Results show that resolution enhancement accurately sharpens the boundaries of different vegetation types, lakes and wetlands. Significant changes in temporal agreement between LPRM products and related datasets are limited to specific areas, such as lakes and coastal areas. Spatial correlations, on the other hand, increase over most of Australia. In addition, hydrological signals from irrigation and water bodies that were absent in the low-resolution soil moisture product become clearly visible after resolution enhancement. The increased information detail in the high-resolution LPRM products should benefit hydrological studies at regional scales.

  19. Ultrahigh resolution optical coherence elastography using a Bessel beam for extended depth of field

    NASA Astrophysics Data System (ADS)

    Curatolo, Andrea; Villiger, Martin; Lorenser, Dirk; Wijesinghe, Philip; Fritz, Alexander; Kennedy, Brendan F.; Sampson, David D.

    2016-03-01

    Visualizing stiffness within the local tissue environment at the cellular and sub-cellular level promises to provide insight into the genesis and progression of disease. In this paper, we propose ultrahigh-resolution optical coherence elastography, and demonstrate three-dimensional imaging of local axial strain of tissues undergoing compressive loading. The technique employs a dual-arm extended focus optical coherence microscope to measure tissue displacement under compression. The system uses a broad bandwidth supercontinuum source for ultrahigh axial resolution, Bessel beam illumination and Gaussian beam detection, maintaining sub-2 μm transverse resolution over nearly 100 μm depth of field, and spectral-domain detection allowing high displacement sensitivity. The system produces strain elastograms with a record resolution (x,y,z) of 2×2×15 μm. We benchmark the advances in terms of resolution and strain sensitivity by imaging a suitable inclusion phantom. We also demonstrate this performance on freshly excised mouse aorta and reveal the mechanical heterogeneity of vascular smooth muscle cells and elastin sheets, otherwise unresolved in a typical, lower resolution optical coherence elastography system.

  20. Extended Depth of Field for High-Resolution Scanning Transmission Electron Microscopy

    SciTech Connect

    Hovden, Robert; Xin, Huolin L.; Muller, David A.

    2010-12-02

    Aberration-corrected scanning transmission electron microscopes (STEMs) provide sub-Angstrom lateral resolution; however, the large convergence angle greatly reduces the depth of field. For microscopes with a small depth of field, information outside of the focal plane quickly becomes blurred and less defined. It may not be possible to image some samples entirely in focus. Extended depth-of-field techniques, however, allow a single image, with all areas in focus, to be extracted from a series of images focused at a range of depths. In recent years, a variety of algorithmic approaches have been employed for bright-field optical microscopy. Here, we demonstrate that some established optical microscopy methods can also be applied to extend the ~6 nm depth of focus of a 100 kV 5th-order aberration-corrected STEM (α{sub max} = 33 mrad) to image Pt-Co nanoparticles on a thick vulcanized carbon support. These techniques allow us to automatically obtain a single image with all the particles in focus as well as a complimentary topography map.

  1. Quantitative comparison of wavelength dependence on penetration depth and imaging contrast for ultrahigh-resolution optical coherence tomography using supercontinuum sources at five wavelength regions

    NASA Astrophysics Data System (ADS)

    Ishida, S.; Nishizawa, N.

    2012-01-01

    Optical coherence tomography (OCT) is a non invasive optical imaging technology for micron-scale cross-sectional imaging of biological tissue and materials. We have been investigating ultrahigh resolution optical coherence tomography (UHR-OCT) using fiber based supercontinuum sources. Although ultrahigh longitudinal resolution was achieved in several center wavelength regions, its low penetration depth is a serious limitation for other applications. To realize ultrahigh resolution and deep penetration depth simultaneously, it is necessary to choose the proper wavelength to maximize the light penetration and enhance the image contrast at deeper depths. Recently, we have demonstrated the wavelength dependence of penetration depth and imaging contrast for ultrahigh resolution OCT at 0.8 μm, 1.3 μm, and 1.7 μm wavelength ranges. In this paper, additionally we used SC sources at 1.06 μm and 1.55 μm, and we have investigated the wavelength dependence of UHR-OCT at five wavelength regions. The image contrast and penetration depth have been discussed in terms of the scattering coefficient and water absorption of samples. Almost the same optical characteristics in longitudinal and lateral resolution, sensitivity, and incident optical power at all wavelength regions were demonstrated. We confirmed the enhancement of image contrast and decreased ambiguity of deeper epithelioid structure at longer wavelength region.

  2. Achievement of a 920-MHz High Resolution NMR

    NASA Astrophysics Data System (ADS)

    Hashi, Kenjiro; Shimizu, Tadashi; Goto, Atsushi; Kiyoshi, Tsukasa; Matsumoto, Shinji; Wada, Hitoshi; Fujito, Teruaki; Hasegawa, Ken-ichi; Yoshikawa, Masatoshi; Miki, Takashi; Ito, Satoshi; Hamada, Mamoru; Hayashi, Seiji

    2002-06-01

    We have developed a 920-MHz NMR system and performed the proton NMR measurement of H 2O and ethylbenzene using the superconducting magnet operating at 21.6 T (920 MHz for proton), which is the highest field produced by a superconducting NMR magnet in the persistent mode. From the NMR measurements, it is verified that both homogeneity and stability of the magnet have a specification sufficient for a high resolution NMR.

  3. SU-E-J-197: Investigation of Microsoft Kinect 2.0 Depth Resolution for Patient Motion Tracking

    SciTech Connect

    Silverstein, E; Snyder, M

    2015-06-15

    Purpose: Investigate the use of the Kinect 2.0 for patient motion tracking during radiotherapy by studying spatial and depth resolution capabilities. Methods: Using code written in C#, depth map data was abstracted from the Kinect to create an initial depth map template indicative of the initial position of an object to be compared to the depth map of the object over time. To test this process, simple setup was created in which two objects were imaged: a 40 cm × 40 cm board covered in non reflective material and a 15 cm × 26 cm textbook with a slightly reflective, glossy cover. Each object, imaged and measured separately, was placed on a movable platform with object to camera distance measured. The object was then moved a specified amount to ascertain whether the Kinect’s depth camera would visualize the difference in position of the object. Results: Initial investigations have shown the Kinect depth resolution is dependent on the object to camera distance. Measurements indicate that movements as small as 1 mm can be visualized for objects as close as 50 cm away. This depth resolution decreases linearly with object to camera distance. At 4 m, the depth resolution had decreased to observe a minimum movement of 1 cm. Conclusion: The improved resolution and advanced hardware of the Kinect 2.0 allows for increase of depth resolution over the Kinect 1.0. Although obvious that the depth resolution should decrease with increasing distance from an object given the decrease in number of pixels representing said object, the depth resolution at large distances indicates its usefulness in a clinical setting.

  4. Image reconstruction enables high resolution imaging at large penetration depths in fluorescence microscopy

    NASA Astrophysics Data System (ADS)

    Dilipkumar, Shilpa; Montalescot, Sandra; Mondal, Partha Pratim

    2013-10-01

    Imaging thick specimen at a large penetration depth is a challenge in biophysics and material science. Refractive index mismatch results in spherical aberration that is responsible for streaking artifacts, while Poissonian nature of photon emission and scattering introduces noise in the acquired three-dimensional image. To overcome these unwanted artifacts, we introduced a two-fold approach: first, point-spread function modeling with correction for spherical aberration and second, employing maximum-likelihood reconstruction technique to eliminate noise. Experimental results on fluorescent nano-beads and fluorescently coated yeast cells (encaged in Agarose gel) shows substantial minimization of artifacts. The noise is substantially suppressed, whereas the side-lobes (generated by streaking effect) drops by 48.6% as compared to raw data at a depth of 150 μm. Proposed imaging technique can be integrated to sophisticated fluorescence imaging techniques for rendering high resolution beyond 150 μm mark.

  5. Concept for a high-resolution thermometer utilizing the temperature dependence of the magnetic penetration depth

    NASA Technical Reports Server (NTRS)

    Shirron, P. J.; Dipirro, M. J.

    1993-01-01

    A thermometer using the temperature dependence of the magnetic penetration depth in superconductors is described which has the potential for temperature resolution, when using a dc SQUID readout, on the order of 1 pK. One such device has been fabricated and characterized to demonstrate proof of concept. It consists of primary and secondary coils of NbTi wire wound on a copper toroidal core on which a thin layer of In (Tc = 3.4 K) has been deposited. The temperature dependence of the mutual inductance, M(T), or self-inductance, is used to detect changes in temperature. Measurements of M(T) have been made with an ac excitation of the primary for various frequencies and peak magnetic field strengths. Estimates of ultimate temperature resolution are given.

  6. Instrument for Achieving High Angular Resolution on the Infrared Telescope

    NASA Technical Reports Server (NTRS)

    Hall, Donald N. B.

    1998-01-01

    Aberrations in stellar images caused by the atmosphere sets a significant limit on angular resolution in ground based astronomy. The largest of these aberrations is the image motion or wavefront tilt. Since the image motion is random it causes a blurring of the image, and this causes a blurring of the image from 0.3 arcseconds to about 0.7 arcseconds. The purpose of the tip-tilt project was to devise a system for the NASA Infrared Telescope Facility that would measure the image movement and correct it by rapidly tilting a mirror in two axes (tip and tilt). The system would involve building a CCD sensor package to measure the image motion, a new top end for the telescope to hold the tip-tilt mirror, a control system, and software. The system was designed to correct images for the facility camera, NSFCAM, and for the facility spectrometer, SPEX. Both of these instruments are equipped with a cold beamsplitter to feed the sensor package.

  7. High-resolution in-depth imaging of optically cleared thick samples using an adaptive SPIM

    PubMed Central

    Masson, Aurore; Escande, Paul; Frongia, Céline; Clouvel, Grégory; Ducommun, Bernard; Lorenzo, Corinne

    2015-01-01

    Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause major changes to the light path resulting in loss of signal and contrast in the deepest regions, thus impairing in-depth imaging capability. These effects are particularly marked when inhomogeneous, complex biological samples are under study. Recently, chemical treatments have been developed to render a sample transparent by homogenizing its refractive index (RI), consequently enabling a reduction of scattering phenomena and a simplification of optical aberration patterns. One drawback of these methods is that the resulting RI of cleared samples does not match the working RI medium generally used for LSFM lenses. This RI mismatch leads to the presence of low-order aberrations and therefore to a significant degradation of image quality. In this paper, we introduce an original optical-chemical combined method based on an adaptive SPIM and a water-based clearing protocol enabling compensation for aberrations arising from RI mismatches induced by optical clearing methods and acquisition of high-resolution in-depth images of optically cleared complex thick samples such as Multi-Cellular Tumour Spheroids. PMID:26576666

  8. High-resolution in-depth imaging of optically cleared thick samples using an adaptive SPIM

    NASA Astrophysics Data System (ADS)

    Masson, Aurore; Escande, Paul; Frongia, Céline; Clouvel, Grégory; Ducommun, Bernard; Lorenzo, Corinne

    2015-11-01

    Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause major changes to the light path resulting in loss of signal and contrast in the deepest regions, thus impairing in-depth imaging capability. These effects are particularly marked when inhomogeneous, complex biological samples are under study. Recently, chemical treatments have been developed to render a sample transparent by homogenizing its refractive index (RI), consequently enabling a reduction of scattering phenomena and a simplification of optical aberration patterns. One drawback of these methods is that the resulting RI of cleared samples does not match the working RI medium generally used for LSFM lenses. This RI mismatch leads to the presence of low-order aberrations and therefore to a significant degradation of image quality. In this paper, we introduce an original optical-chemical combined method based on an adaptive SPIM and a water-based clearing protocol enabling compensation for aberrations arising from RI mismatches induced by optical clearing methods and acquisition of high-resolution in-depth images of optically cleared complex thick samples such as Multi-Cellular Tumour Spheroids.

  9. A high-resolution time-depth view of dimethylsulphide cycling in the surface sea.

    PubMed

    Royer, S-J; Galí, M; Mahajan, A S; Ross, O N; Pérez, G L; Saltzman, E S; Simó, R

    2016-01-01

    Emission of the trace gas dimethylsulphide (DMS) from the ocean influences the chemical and optical properties of the atmosphere, and the olfactory landscape for foraging marine birds, turtles and mammals. DMS concentration has been seen to vary across seasons and latitudes with plankton taxonomy and activity, and following the seascape of ocean's physics. However, whether and how does it vary at the time scales of meteorology and day-night cycles is largely unknown. Here we used high-resolution measurements over time and depth within coherent water patches in the open sea to show that DMS concentration responded rapidly but resiliently to mesoscale meteorological perturbation. Further, it varied over diel cycles in conjunction with rhythmic photobiological indicators in phytoplankton. Combining data and modelling, we show that sunlight switches and tunes the balance between net biological production and abiotic losses. This is an outstanding example of how biological diel rhythms affect biogeochemical processes. PMID:27578300

  10. A high-resolution time-depth view of dimethylsulphide cycling in the surface sea

    PubMed Central

    Royer, S.-J.; Galí, M.; Mahajan, A. S.; Ross, O. N.; Pérez, G. L.; Saltzman, E. S.; Simó, R.

    2016-01-01

    Emission of the trace gas dimethylsulphide (DMS) from the ocean influences the chemical and optical properties of the atmosphere, and the olfactory landscape for foraging marine birds, turtles and mammals. DMS concentration has been seen to vary across seasons and latitudes with plankton taxonomy and activity, and following the seascape of ocean’s physics. However, whether and how does it vary at the time scales of meteorology and day-night cycles is largely unknown. Here we used high-resolution measurements over time and depth within coherent water patches in the open sea to show that DMS concentration responded rapidly but resiliently to mesoscale meteorological perturbation. Further, it varied over diel cycles in conjunction with rhythmic photobiological indicators in phytoplankton. Combining data and modelling, we show that sunlight switches and tunes the balance between net biological production and abiotic losses. This is an outstanding example of how biological diel rhythms affect biogeochemical processes. PMID:27578300

  11. A high-resolution time-depth view of dimethylsulphide cycling in the surface sea

    NASA Astrophysics Data System (ADS)

    Royer, S.-J.; Galí, M.; Mahajan, A. S.; Ross, O. N.; Pérez, G. L.; Saltzman, E. S.; Simó, R.

    2016-08-01

    Emission of the trace gas dimethylsulphide (DMS) from the ocean influences the chemical and optical properties of the atmosphere, and the olfactory landscape for foraging marine birds, turtles and mammals. DMS concentration has been seen to vary across seasons and latitudes with plankton taxonomy and activity, and following the seascape of ocean’s physics. However, whether and how does it vary at the time scales of meteorology and day-night cycles is largely unknown. Here we used high-resolution measurements over time and depth within coherent water patches in the open sea to show that DMS concentration responded rapidly but resiliently to mesoscale meteorological perturbation. Further, it varied over diel cycles in conjunction with rhythmic photobiological indicators in phytoplankton. Combining data and modelling, we show that sunlight switches and tunes the balance between net biological production and abiotic losses. This is an outstanding example of how biological diel rhythms affect biogeochemical processes.

  12. The impact from survey depth and resolution on the morphological classification of galaxies

    NASA Astrophysics Data System (ADS)

    Pović, M.; Márquez, I.; Masegosa, J.; Perea, J.; Olmo, A. del; Simpson, C.; Aguerri, J. A. L.; Ascaso, B.; Jiménez-Teja, Y.; López-Sanjuan, C.; Molino, A.; Pérez-García, A. M.; Viironen, K.; Husillos, C.; Cristóbal-Hornillos, D.; Caldwell, C.; Benítez, N.; Alfaro, E.; Aparicio-Villegas, T.; Broadhurst, T.; Cabrera-Caño, J.; Castander, F. J.; Cepa, J.; Cerviño, M.; Fernández-Soto, A.; Delgado, R. M. González; Infante, L.; Martínez, V. J.; Moles, M.; Prada, F.; Quintana, J. M.

    2015-10-01

    We consistently analyse for the first time the impact of survey depth and spatial resolution on the most used morphological parameters for classifying galaxies through non-parametric methods: Abraham and Conselice-Bershady concentration indices, Gini, M20 moment of light, asymmetry, and smoothness. Three different non-local data sets are used, Advanced Large Homogeneous Area Medium Band Redshift Astronomical (ALHAMBRA) and Subaru/XMM-Newton Deep Survey (SXDS, examples of deep ground-based surveys), and Cosmos Evolution Survey (COSMOS, deep space-based survey). We used a sample of 3000 local, visually classified galaxies, measuring their morphological parameters at their real redshifts (z ˜ 0). Then we simulated them to match the redshift and magnitude distributions of galaxies in the non-local surveys. The comparisons of the two sets allow us to put constraints on the use of each parameter for morphological classification and evaluate the effectiveness of the commonly used morphological diagnostic diagrams. All analysed parameters suffer from biases related to spatial resolution and depth, the impact of the former being much stronger. When including asymmetry and smoothness in classification diagrams, the noise effects must be taken into account carefully, especially for ground-based surveys. M20 is significantly affected, changing both the shape and range of its distribution at all brightness levels. We suggest that diagnostic diagrams based on 2-3 parameters should be avoided when classifying galaxies in ground-based surveys, independently of their brightness; for COSMOS they should be avoided for galaxies fainter than F814 = 23.0. These results can be applied directly to surveys similar to ALHAMBRA, SXDS and COSMOS, and also can serve as an upper/lower limit for shallower/deeper ones.

  13. Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

    PubMed Central

    Tao, Aizhu; Peterson, Kristen A; Jiang, Hong; Shao, Yilei; Zhong, Jianguang; Carey, Frank C; Rosen, Elias P; Wang, Jianhua

    2013-01-01

    We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal–scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision. PMID:23976840

  14. Reliability of multiresolution deconvolution for improving depth resolution in SIMS analysis

    NASA Astrophysics Data System (ADS)

    Boulakroune, M.'Hamed

    2016-11-01

    This paper deals the effectiveness and reliability of multiresolution deconvolution algorithm for recovery Secondary Ions Mass Spectrometry, SIMS, profiles altered by the measurement. This new algorithm is characterized as a regularized wavelet transform. It combines ideas from Tikhonov Miller regularization, wavelet analysis and deconvolution algorithms in order to benefit from the advantages of each. The SIMS profiles were obtained by analysis of two structures of boron in a silicon matrix using a Cameca-Ims6f instrument at oblique incidence. The first structure is large consisting of two distant wide boxes and the second one is thin structure containing ten delta-layers in which the deconvolution by zone was applied. It is shown that this new multiresolution algorithm gives best results. In particular, local application of the regularization parameter of blurred and estimated solutions at each resolution level provided to smoothed signals without creating artifacts related to noise content in the profile. This led to a significant improvement in the depth resolution and peaks' maximums.

  15. Deriving High Resolution UV Aerosol Optical Depth over East Asia using CAI-OMI Joint Retrieval

    NASA Astrophysics Data System (ADS)

    Go, S.; Kim, J.; KIM, M.; Lee, S.

    2015-12-01

    Monitoring aerosols using near UV spectral region have been successfully performed over decades by Ozong Monitoring Instruments (OMI) with benefit of strong aerosol signal over continuous dark surface reflectance, both land and ocean. However, because of big foot print of OMI, the cloud contamination error was a big issue in the UV aerosol algorithm. In the present study, high resolution UV aerosol optical depth (AOD) over East Asia was derived by collaborating the Greenhouse gases Observing SATellite/Thermal And Near infrared Sensor for carbon Observation (GOSAT/TANSO)-Cloud and Aerosol Imager (CAI) and OMI together. AOD of 0.1 degree grid resolution was retrieved using CAI band 1 (380nm) by bring OMI lv.2 aerosol type, single scattering albedo, and aerosol layer peak height in 1 degree grid resolution. Collocation of the two dataset within the 0.5 degree grid with time difference of OMI and CAI less than 5 minute was selected. Selected region becomes wider as it goes to the higher latitude. Also, calculated degradation factor of 1.57 was applied to CAI band1 (380nm) by comparing normalized radiance and Lambertian Equivalent Reflectivity (LER) of both sensors. The calculated degradation factor was reasonable over dark scene, but inconsistent over cirrus cloud and bright area. Then, surface reflectance was developed by compositing CAI LER minimum data over three month period, since the infrequent sampling rate associated with the three-day recursion period of GOSAT and the narrow CAI swath of 1000 km. To retrieve AOD, look up table (LUT) was generated using radiative transfer model VLIDORT NGST. Finally, the retrieved AOD was validated with AERONET ground based measurement data during the Dragon-NE Asia campaign in 2012.

  16. Comparison of Curricular Breadth, Depth, and Recurrence and Physics Achievement of TIMSS Population 3 Countries

    ERIC Educational Resources Information Center

    Murdock, John

    2008-01-01

    This study is a secondary analysis of data from the 1995 administration of the Third International Mathematics and Science Study (TIMSS). The purpose is to compare the breadth, depth, and recurrence of the typical physics curriculum in the United States with the typical curricula in different countries and to determine whether there are…

  17. Depth and resolution characterization of two-photon photoacoustic spectroscopy for noninvasive subsurface chemical diagnostics

    NASA Astrophysics Data System (ADS)

    Dahal, Sudhir; Kiser, John B.; Cullum, Brian M.

    2011-05-01

    Photoacoustic spectroscopy is a powerful optical biopsy technique that enables rapid tumor diagnosis in situ. It has also been reported that photoacoustic spectroscopy can be used to diagnose pre-malignant tissue based on the chemical differences between healthy and pre-malignant tissues. Since the acoustic signals obtained from tissues in these analyses suffer from minimum damping, photoacoustic spectroscopy can be highly sensitive. This paper focuses on the characterization of a novel multiphoton excited photoacoustic methodology for margining of malignant and pre-malignant tissues. The two-photon excitation process in tissues using nanosecond laser pulses produces ultrasonic signals that transmit through tissue with minimal attenuation. Additionally, the two-photon excitation process is highly localized since only ballistic photons contribute to the excitation process; thereby eliminating potential absorption events in tissue not of interest (i.e., along the beam path) and increasing the spatial resolution of the diagnostic technique to that achievable via optics. This work characterizes the two-photon excitation process for photoacoustic signal measurements on a model dye. Using gelatin phantoms to mimic real tissues, tissue penetration studies were performed, revealing chemical species as deep as 1.3 cm in the tissue can easily be detected using this methodology. Furthermore, the resolution of this multiphoton excitation process was determined to be as great as 50 μm (near cellular level resolution).

  18. Wavelength scanning achieves pixel super-resolution in holographic on-chip microscopy

    NASA Astrophysics Data System (ADS)

    Luo, Wei; Göröcs, Zoltan; Zhang, Yibo; Feizi, Alborz; Greenbaum, Alon; Ozcan, Aydogan

    2016-03-01

    Lensfree holographic on-chip imaging is a potent solution for high-resolution and field-portable bright-field imaging over a wide field-of-view. Previous lensfree imaging approaches utilize a pixel super-resolution technique, which relies on sub-pixel lateral displacements between the lensfree diffraction patterns and the image sensor's pixel-array, to achieve sub-micron resolution under unit magnification using state-of-the-art CMOS imager chips, commonly used in e.g., mobile-phones. Here we report, for the first time, a wavelength scanning based pixel super-resolution technique in lensfree holographic imaging. We developed an iterative super-resolution algorithm, which generates high-resolution reconstructions of the specimen from low-resolution (i.e., under-sampled) diffraction patterns recorded at multiple wavelengths within a narrow spectral range (e.g., 10-30 nm). Compared with lateral shift-based pixel super-resolution, this wavelength scanning approach does not require any physical shifts in the imaging setup, and the resolution improvement is uniform in all directions across the sensor-array. Our wavelength scanning super-resolution approach can also be integrated with multi-height and/or multi-angle on-chip imaging techniques to obtain even higher resolution reconstructions. For example, using wavelength scanning together with multi-angle illumination, we achieved a halfpitch resolution of 250 nm, corresponding to a numerical aperture of 1. In addition to pixel super-resolution, the small scanning steps in wavelength also enable us to robustly unwrap phase, revealing the specimen's optical path length in our reconstructed images. We believe that this new wavelength scanning based pixel super-resolution approach can provide competitive microscopy solutions for high-resolution and field-portable imaging needs, potentially impacting tele-pathology applications in resource-limited-settings.

  19. Optical depth of the Martian atmosphere and surface albedo from high-resolution orbiter images

    NASA Astrophysics Data System (ADS)

    Petrova, E. V.; Hoekzema, N. M.; Markiewicz, W. J.; Thomas, N.; Stenzel, O. J.

    2012-01-01

    In this paper we describe and evaluate the so-called shadow method. This method can be used to estimate the optical depth of the Martian atmosphere from the differences in brightness between shadowed and sunlit regions observed from an orbiter. We present elaborate and simplified versions of the method and analyze the capabilities and the sources of errors. It proves essential to choose shadowed and sunlit comparison regions with similar surface properties. Accurate knowledge of the observing geometry, including the slopes of the observed region, is important as well, since the procedure should be corrected for the non-horizontal surface. Moreover, the elaborate version of the shadow method can be sensitive to (i) the optical model of aerosols and (ii) the assumed bi-directional reflectance function of the surface. To obtain reliable estimates, the analyzed images must have a high spatial resolution, which the HiRISE camera onboard the MRO provides. We tested the shadow method on two HiRISE images of Victoria crater (TRA_0873_1780 and PSP_001414_1780) that were taken while this crater was the exploration site of the Opportunity rover. While the rover measured optical depth τ approximately in the ranges from 0.43 to 0.53 and from 0.53 to 0.59 by imaging the sun, our shadow procedure yielded τ about 0.50 and 0.575, respectively (from the HiRISE's red images). Thus, the agreement is quite good. The obtained estimates of the surface albedo are about 0.20 and 0.17, respectively.

  20. Achievable spatial resolution of time-resolved transillumination imaging systems which utilize multiply scattered light

    NASA Astrophysics Data System (ADS)

    Moon, J. A.; Battle, P. R.; Bashkansky, M.; Mahon, R.; Duncan, M. D.; Reintjes, J.

    1996-01-01

    We describe theoretically and measure experimentally the best achievable time-dependent point-spread-function of light in the presence of strong turbidity. We employ the rescaled isotropic-scattering solution to the time-dependent radiative transfer equation to examine three mathematically distinct limits of photonic transport: the ballistic, quasidiffuse, and diffuse limits. In all cases we follow the constraint that a minimum fractional number of launched photons must be received before the time-integrating detector is turned off. We show how the achievable ballistic resolution maps into the diffusion-limited achievable resolution, and verify this behavior experimentally by using a coherently amplified Raman polarization gate imaging system. We are able to quantitatively fit the measured best achievable resolution by empirically rescaling the scattering length in the model.

  1. Depth Probing Soft X-ray Microprobe (DPSXRM) for High Resolution Probing of Earth's Microstructural Samples

    NASA Astrophysics Data System (ADS)

    Dikedi, P. N.

    2015-12-01

    The Cambrian explosion; occurrence of landslides in very dry weather conditions; rockslides; dead, shriveled-up and crumbled leaves possessing fossil records with the semblance of well preserved, flat leaves; abundance of trilobite tracks in lower and higher rock layers; and sailing stones are enigmas demanding demystifications. These enigmas could be elucidated when data on soil structure, texture and strength are provided by some device with submicrometre accuracy; for these and other reasons, the design of a Depth Probing Soft X-ray Microprobe (DPSXRM), is being proposed; it is expected to deliver soft X-rays, at spatial resolution, ϛ≥600nm and to probe at the depth of 0.5m in 17s. The microprobe is portable compared to a synchrotron radiation facility (Diamond Light Source has land size of 43,300m2); spatial resolution,ϛ , of the DPSXRM surpasses those of the X-ray Fluorescence microanalysis (10µm), electron microprobe (1-3µm) and ion microprobe (5->30µm); the DPSXRM has allowance for multiple targets. Vanadium and Manganese membranes are proposed owing to respective 4.952KeV VKα1 and 5.899KeV MnKα1 X-rays emitted, which best suits micro-probing of Earth's microstructural samples. Compound systems like the Kirk-Patrick and Baez and Wolter optics, aspheric mirrors like elliptical and parabolic optics, small apertures and Abbe sine condition are employed to reduce or remove astigmatism, obliquity, comatic and spherical aberrations—leading to good image quality. Results show that 5.899KeV MnKα1 and 4.952KeV VKα1 soft X-rays will travel a distance of 2.75mm to form circular patches of radii 2.2mm and 2.95mm respectively. Zone plate with nth zone radius of 1.5mm must be positioned 1.5mm and 2mm from the electron gun if circular patches must be formed from 4.952KeV VKα1 and 5.899KeV MnKα1 soft X-rays respectively. The focal lengths of 0.25μm≤ƒ≤1.50μm and 0.04μm≤ƒ≤0.2μm covered by 4.952KeV VKα1 and 5.899KeV Mn Kα1 soft X-Rays, will

  2. Axial resolution improvement in spectral domain optical coherence tomography using a depth-adaptive maximum-a-posterior framework

    NASA Astrophysics Data System (ADS)

    Boroomand, Ameneh; Tan, Bingyao; Wong, Alexander; Bizheva, Kostadinka

    2015-03-01

    The axial resolution of Spectral Domain Optical Coherence Tomography (SD-OCT) images degrades with scanning depth due to the limited number of pixels and the pixel size of the camera, any aberrations in the spectrometer optics and wavelength dependent scattering and absorption in the imaged object [1]. Here we propose a novel algorithm which compensates for the blurring effect of these factors of the depth-dependent axial Point Spread Function (PSF) in SDOCT images. The proposed method is based on a Maximum A Posteriori (MAP) reconstruction framework which takes advantage of a Stochastic Fully Connected Conditional Random Field (SFCRF) model. The aim is to compensate for the depth-dependent axial blur in SD-OCT images and simultaneously suppress the speckle noise which is inherent to all OCT images. Applying the proposed depth-dependent axial resolution enhancement technique to an OCT image of cucumber considerably improved the axial resolution of the image especially at higher imaging depths and allowed for better visualization of cellular membrane and nuclei. Comparing the result of our proposed method with the conventional Lucy-Richardson deconvolution algorithm clearly demonstrates the efficiency of our proposed technique in better visualization and preservation of fine details and structures in the imaged sample, as well as better speckle noise suppression. This illustrates the potential usefulness of our proposed technique as a suitable replacement for the hardware approaches which are often very costly and complicated.

  3. Evaluation of multi-resolution satellite sensors for assessing water quality and bottom depth of Lake Garda.

    PubMed

    Giardino, Claudia; Bresciani, Mariano; Cazzaniga, Ilaria; Schenk, Karin; Rieger, Patrizia; Braga, Federica; Matta, Erica; Brando, Vittorio E

    2014-12-15

    In this study we evaluate the capabilities of three satellite sensors for assessing water composition and bottom depth in Lake Garda, Italy. A consistent physics-based processing chain was applied to Moderate Resolution Imaging Spectroradiometer (MODIS), Landsat-8 Operational Land Imager (OLI) and RapidEye. Images gathered on 10 June 2014 were corrected for the atmospheric effects with the 6SV code. The computed remote sensing reflectance (Rrs) from MODIS and OLI were converted into water quality parameters by adopting a spectral inversion procedure based on a bio-optical model calibrated with optical properties of the lake. The same spectral inversion procedure was applied to RapidEye and to OLI data to map bottom depth. In situ measurements of Rrs and of concentrations of water quality parameters collected in five locations were used to evaluate the models. The bottom depth maps from OLI and RapidEye showed similar gradients up to 7 m (r = 0.72). The results indicate that: (1) the spatial and radiometric resolutions of OLI enabled mapping water constituents and bottom properties; (2) MODIS was appropriate for assessing water quality in the pelagic areas at a coarser spatial resolution; and (3) RapidEye had the capability to retrieve bottom depth at high spatial resolution. Future work should evaluate the performance of the three sensors in different bio-optical conditions.

  4. Evaluation of Multi-Resolution Satellite Sensors for Assessing Water Quality and Bottom Depth of Lake Garda

    PubMed Central

    Giardino, Claudia; Bresciani, Mariano; Cazzaniga, Ilaria; Schenk, Karin; Rieger, Patrizia; Braga, Federica; Matta, Erica; Brando, Vittorio E.

    2014-01-01

    In this study we evaluate the capabilities of three satellite sensors for assessing water composition and bottom depth in Lake Garda, Italy. A consistent physics-based processing chain was applied to Moderate Resolution Imaging Spectroradiometer (MODIS), Landsat-8 Operational Land Imager (OLI) and RapidEye. Images gathered on 10 June 2014 were corrected for the atmospheric effects with the 6SV code. The computed remote sensing reflectance (Rrs) from MODIS and OLI were converted into water quality parameters by adopting a spectral inversion procedure based on a bio-optical model calibrated with optical properties of the lake. The same spectral inversion procedure was applied to RapidEye and to OLI data to map bottom depth. In situ measurements of Rrs and of concentrations of water quality parameters collected in five locations were used to evaluate the models. The bottom depth maps from OLI and RapidEye showed similar gradients up to 7 m (r = 0.72). The results indicate that: (1) the spatial and radiometric resolutions of OLI enabled mapping water constituents and bottom properties; (2) MODIS was appropriate for assessing water quality in the pelagic areas at a coarser spatial resolution; and (3) RapidEye had the capability to retrieve bottom depth at high spatial resolution. Future work should evaluate the performance of the three sensors in different bio-optical conditions. PMID:25517691

  5. Evaluation of multi-resolution satellite sensors for assessing water quality and bottom depth of Lake Garda.

    PubMed

    Giardino, Claudia; Bresciani, Mariano; Cazzaniga, Ilaria; Schenk, Karin; Rieger, Patrizia; Braga, Federica; Matta, Erica; Brando, Vittorio E

    2014-01-01

    In this study we evaluate the capabilities of three satellite sensors for assessing water composition and bottom depth in Lake Garda, Italy. A consistent physics-based processing chain was applied to Moderate Resolution Imaging Spectroradiometer (MODIS), Landsat-8 Operational Land Imager (OLI) and RapidEye. Images gathered on 10 June 2014 were corrected for the atmospheric effects with the 6SV code. The computed remote sensing reflectance (Rrs) from MODIS and OLI were converted into water quality parameters by adopting a spectral inversion procedure based on a bio-optical model calibrated with optical properties of the lake. The same spectral inversion procedure was applied to RapidEye and to OLI data to map bottom depth. In situ measurements of Rrs and of concentrations of water quality parameters collected in five locations were used to evaluate the models. The bottom depth maps from OLI and RapidEye showed similar gradients up to 7 m (r = 0.72). The results indicate that: (1) the spatial and radiometric resolutions of OLI enabled mapping water constituents and bottom properties; (2) MODIS was appropriate for assessing water quality in the pelagic areas at a coarser spatial resolution; and (3) RapidEye had the capability to retrieve bottom depth at high spatial resolution. Future work should evaluate the performance of the three sensors in different bio-optical conditions. PMID:25517691

  6. Depth resolution at organic interfaces sputtered by argon gas cluster ions: the effect of energy, angle and cluster size.

    PubMed

    Seah, M P; Spencer, S J; Havelund, R; Gilmore, I S; Shard, A G

    2015-10-01

    An analysis is presented of the effect of experimental parameters such as energy, angle and cluster size on the depth resolution in depth profiling organic materials using Ar gas cluster ions. The first results are presented of the incident ion angle dependence of the depth resolution, obtained at the Irganox 1010 to silicon interface, from profiles by X-ray photoelectron spectrometry (XPS). By analysis of all relevant published depth profile data, it is shown that such data, from delta layers in secondary ion mass spectrometry (SIMS), correlate with the XPS data from interfaces if it is assumed that the monolayers of the Irganox 1010 adjacent to the wafer substrate surface have an enhanced sputtering rate. SIMS data confirm this enhancement. These results show that the traditional relation for the depth resolution, FWHM = 2.1Y(1/3) or slightly better, FWHM = P(X)Y(1/3)/n(0.2), where n is the argon gas cluster size, and P(X) is a parameter for each material are valid both at the 45° incidence angle of the argon gas cluster sputtering ions used in most studies and at all angles from 0° to 80°. This implies that, for optimal depth profile resolution, 0° or >75° incidence may be significantly better than the 45° traditionally used, especially for the low energy per atom settings required for the best resolved profiles in organic materials. A detailed analysis, however, shows that the FWHM requires a constant contribution added in quadrature to the above such that there are minimal improvements at 0° or greater than 75°. A critical test at 75° confirms the presence of this constant contribution.

  7. Social Perspective Taking: A Facilitating Aptitude for Conflict Resolution, Historical Empathy, and Social Studies Achievement

    ERIC Educational Resources Information Center

    Gehlbach, Hunter

    2004-01-01

    This article examines the relationship between social perspective taking (SPT) and student achievement in three domains: conflict resolution, historical empathy, and social studies grades. Although many have asserted that SPT relates to important educational outcomes, varying conceptualizations of SPT have impeded researchers' abilities to assess…

  8. High-resolution, dual-depth spectral-domain optical coherence tomography with interlaced detection for whole-eye imaging.

    PubMed

    Kim, Hyung-Jin; Kim, Pil Un; Hyeon, Min Gyu; Choi, Youngwoon; Kim, Jeehyun; Kim, Beop-Min

    2016-09-10

    Dual-depth spectral-domain optical coherence tomography (SD-OCT) enables high-resolution in vivo whole-eye imaging. Two orthogonally polarized beams from a source are focused simultaneously on two axial positions of the anterior segment and the retina. For the detector arm, a 1×2 ultrafast optical switch sequentially delivers two spectral interference signals to a single spectrometer, which extends the in-air axial depth range up to 9.44 mm. An off-pivot complex conjugate removal technique doubles the depth range for all anterior segment imaging. The graphics-processing-unit-based parallel signal processing algorithm supports fast two- and three-dimensional image displays. The obtained high-resolution anterior and retinal images are measured biometrically. The dual-depth SD-OCT system has an axial resolution of ∼6.4  μm in air, and the sensitivity is 91.79 dB at 150 μm from the zero-delay line. PMID:27661354

  9. Determination of water depth with high-resolution satellite imagery over variable bottom types

    USGS Publications Warehouse

    Stumpf, Richard P.; Holderied, Kristine; Sinclair, Mark

    2003-01-01

    A standard algorithm for determining depth in clear water from passive sensors exists; but it requires tuning of five parameters and does not retrieve depths where the bottom has an extremely low albedo. To address these issues, we developed an empirical solution using a ratio of reflectances that has only two tunable parameters and can be applied to low-albedo features. The two algorithms--the standard linear transform and the new ratio transform--were compared through analysis of IKONOS satellite imagery against lidar bathymetry. The coefficients for the ratio algorithm were tuned manually to a few depths from a nautical chart, yet performed as well as the linear algorithm tuned using multiple linear regression against the lidar. Both algorithms compensate for variable bottom type and albedo (sand, pavement, algae, coral) and retrieve bathymetry in water depths of less than 10-15 m. However, the linear transform does not distinguish depths >15 m and is more subject to variability across the studied atolls. The ratio transform can, in clear water, retrieve depths in >25 m of water and shows greater stability between different areas. It also performs slightly better in scattering turbidity than the linear transform. The ratio algorithm is somewhat noisier and cannot always adequately resolve fine morphology (structures smaller than 4-5 pixels) in water depths >15-20 m. In general, the ratio transform is more robust than the linear transform.

  10. Correction of depth-dependent aberrations in 3D single-molecule localization and super-resolution microscopy.

    PubMed

    McGorty, Ryan; Schnitzbauer, Joerg; Zhang, Wei; Huang, Bo

    2014-01-15

    Single-molecule switching based super-resolution microscopy techniques have been extended into three dimensions through various 3D single-molecule localization methods. However, the localization accuracy in z can be severely degraded by the presence of aberrations, particularly the spherical aberration introduced by the refractive index mismatch when imaging into an aqueous sample with an oil immersion objective. This aberration confines the imaging depth in most experiments to regions close to the coverslip. Here we show a method to obtain accurate, depth-dependent z calibrations by measuring the point spread function (PSF) at the coverslip surface, calculating the microscope pupil function through phase retrieval, and then computing the depth-dependent PSF with the addition of spherical aberrations. We demonstrate experimentally that this method can maintain z localization accuracy over a large range of imaging depths. Our super-resolution images of a mammalian cell nucleus acquired between 0 and 2.5 μm past the coverslip show that this method produces accurate z localizations even in the deepest focal plane.

  11. High-resolution magnetic penetration depth and inhomogeneities in locally noncentrosymmetric SrPtAs

    NASA Astrophysics Data System (ADS)

    Landaeta, J. F.; Taylor, S. V.; Bonalde, I.; Rojas, C.; Nishikubo, Y.; Kudo, K.; Nohara, M.

    2016-02-01

    We present a magnetic-penetration-depth study on polycrystalline and granular samples of SrPtAs, a pnictide superconductor with a hexagonal structure containing PtAs layers that individually break inversion symmetry (local noncentrosymmetry). Compact samples show a clear-cut s -wave-type BCS behavior, which we consider to be the intrinsic penetration depth of SrPtAs. Granular samples display a sample-dependent second diamagnetic drop, attributed to the intergrain coupling. Our experimental results point to a nodeless isotropic superconducting energy gap in SrPtAs, which puts strong constraints on the driven mechanism for superconductivity and the order parameter symmetry of this compound.

  12. Medium energy ion scattering for the high depth resolution characterisation of high-k dielectric layers of nanometer thickness

    NASA Astrophysics Data System (ADS)

    van den Berg, J. A.; Reading, M. A.; Bailey, P.; Noakes, T. Q. C.; Adelmann, C.; Popovici, M.; Tielens, H.; Conard, T.; de Gendt, S.; van Elshocht, S.

    2013-09-01

    Medium energy ion scattering (MEIS) using, typically, 100-200 keV H+ or He+ ions derives it ability to characterise nanolayers from the fact that the energy after backscattering depends (i) on the elastic energy loss suffered in a single collision with a target atom and (ii) on the inelastic energy losses on its incoming and outgoing trajectories. From the former the mass of the atom can be determined and from the latter its depth. Thus MEIS yields depth dependent compositional and structural information, with high depth resolution (sub-nm near the surface) and good sensitivity for all but the lighter masses. It is particularly well suited for the depth analysis of high-k multilayers of nanometer thickness. Accurate quantification of the depth distributions of atomic species can be obtained using suitable spectrum simulation. In the present paper, important aspects of MEIS including quantification, depth resolution and spectrum simulation are briefly discussed. The capabilities of the technique in terms of the high depth resolution layer compositional and structural information it yields, is illustrated with reference to the detailed characterisation of a range of high-k nanolayer and multilayer structures for current microelectronic devices or those still under development: (i) HfO2 and HfSiOx for gate dielectric applications, including a TiN/Al2O3/HfO2/SiO2/Si structure, (ii) TiN/SrTiO3/TiN and (iii) TiO2/Ru/TiN multilayer structures for metal-insulator-metal capacitors (MIMcaps) in DRAM applications. The unique information provided by the technique is highlighted by its clear capability to accurately quantify the composition profiles and thickness of nanolayers and complex multilayers as grown, and to identify the nature and extent of atom redistribution (e.g. intermixing, segregation) during layer deposition, annealing and plasma processing. The ability makes it a valuable tool in the development of the nanostructures that will become increasingly important as

  13. Three-dimensional imaging characteristics and depth resolution in digital holographic three-dimensional imaging spectrometry

    NASA Astrophysics Data System (ADS)

    Obara, Masaki; Yoshimori, Kyu

    2015-07-01

    A four-dimensional impulse response function for the digital holographic three-dimensional imaging spectrometry has been fully derived in closed form. Due to its factorizing nature of the mathematical expression of four-dimensional impulse response function, three-dimensional spatial part of impulse response function directly corresponds to threedimensional point spread function of in-line digital holography with rectangular aperture. Based on these mathematical results, this paper focuses on the investigation of spectral resolution and three-dimensional spatial resolution in digital holographic three-dimensional imaging spectrometry and digital holography. We found that the theoretical prediction agree well with the experimental results. This work suggests a new criterion and estimate method regarding threedimensional spatial resolution of in-line digital holography.

  14. Improved depth resolution in near-infrared diffuse reflectance spectroscopy using obliquely oriented fibers

    NASA Astrophysics Data System (ADS)

    Thilwind, Rachel Estelle; 't Hooft, Gert; Uzunbajakava, Natallia E.

    2009-03-01

    We demonstrate a significant improvement of depth selectivity when using obliquely oriented fibers for near-infrared (NIR) diffuse reflectance spectroscopy. This is confirmed by diffuse reflectance measurements of a two-layer tissue-mimicking phantom across the spectral range from 1000 to 1940 nm. The experimental proof is supported by Monte Carlo simulations. The results reveal up to fourfold reduction in the mean optical penetration depth, twofold reduction in its variation, and a decrease in the number of scattering events when a single fiber is oriented at an angle of 60 deg. The effect of reducing the mean optical penetration depth is enhanced by orienting both fibers inwardly. Using outwardly oriented fibers enables more selective probing of deeper layers, while reducing the contribution from surface layers. We further demonstrate that the effect of an inward oblique arrangement can be approximated to a decrease in fiber-to-fiber separation in the case of a perpendicular fiber arrangement. This approximation is valid in the weak- or absorption-free regime. Our results assert the advantages of using obliquely oriented fibers when attempting to specifically address superficial tissue layers, for example, for skin cancer detection, or in noninvasive glucose monitoring. Such flexibility could be further advantageous in a range of minimally invasive applications, including catheter-based interventions.

  15. Fast time-resolved electrostatic force microscopy: Achieving sub-cycle time resolution.

    PubMed

    Karatay, Durmus U; Harrison, Jeffrey S; Glaz, Micah S; Giridharagopal, Rajiv; Ginger, David S

    2016-05-01

    The ability to measure microsecond- and nanosecond-scale local dynamics below the diffraction limit with widely available atomic force microscopy hardware would enable new scientific studies in fields ranging from biology to semiconductor physics. However, commercially available scanning-probe instruments typically offer the ability to measure dynamics only on time scales of milliseconds to seconds. Here, we describe in detail the implementation of fast time-resolved electrostatic force microscopy using an oscillating cantilever as a means to measure fast local dynamics following a perturbation to a sample. We show how the phase of the oscillating cantilever relative to the perturbation event is critical to achieving reliable sub-cycle time resolution. We explore how noise affects the achievable time resolution and present empirical guidelines for reducing noise and optimizing experimental parameters. Specifically, we show that reducing the noise on the cantilever by using photothermal excitation instead of piezoacoustic excitation further improves time resolution. We demonstrate the discrimination of signal rise times with time constants as fast as 10 ns, and simultaneous data acquisition and analysis for dramatically improved image acquisition times. PMID:27250430

  16. High-resolution chemical depth profiling of solid material using a miniature laser ablation/ionization mass spectrometer.

    PubMed

    Grimaudo, Valentine; Moreno-García, Pavel; Riedo, Andreas; Neuland, Maike B; Tulej, Marek; Broekmann, Peter; Wurz, Peter

    2015-02-17

    High-resolution chemical depth profiling measurements of copper films are presented. The 10 μm thick copper test samples were electrodeposited on a Si-supported Cu seed under galvanostatic conditions in the presence of particular plating additives (SPS, Imep, PEI, and PAG) used in the semiconductor industry for the on-chip metallization of interconnects. To probe the trend of these plating additives toward inclusion into the deposit upon growth, quantitative elemental mass spectrometric measurements at trace level concentration were conducted by using a sensitive miniature laser ablation ionization mass spectrometer (LIMS), originally designed and developed for in situ space exploration. An ultrashort pulsed laser system (τ ∼ 190 fs, λ = 775 nm) was used for ablation and ionization of sample material. We show that with our LIMS system, quantitative chemical mass spectrometric analysis with an ablation rate at the subnanometer level per single laser shot can be conducted. The measurement capabilities of our instrument, including the high vertical depth resolution coupled with high detection sensitivity of ∼10 ppb, high dynamic range ≥10(8), measurement accuracy and precision, is of considerable interest in various fields of application, where investigations with high lateral and vertical resolution of the chemical composition of solid materials are required, these include, e.g., wafers from semiconductor industry or studies on space weathered samples in space research.

  17. Achieving selective interrogation and sub-wavelength resolution in thin plates with embedded metamaterial acoustic lenses

    SciTech Connect

    Semperlotti, F. Zhu, H.

    2014-08-07

    In this study, we present an approach to ultrasonic beam-forming and high resolution identification of acoustic sources having critical implications for applications such as structural health monitoring. The proposed concept is based on the design of dynamically tailored structural elements via embedded acoustic metamaterial lenses. This approach provides a completely new alternative to conventional phased-array technology enabling the formation of steerable and collimated (or focused) ultrasonic beams by exploiting a single transducer. Numerical results show that the ultrasonic beam can be steered by simply tuning the frequency of the excitation. Also, the embedded lens can be designed to achieve sub-wavelength resolution to clustered acoustic sources, which is a typical scenario encountered in incipient structural damage.

  18. High-resolution monitoring of the hole depth during ultrafast laser ablation drilling by diode laser self-mixing interferometry.

    PubMed

    Mezzapesa, Francesco P; Ancona, Antonio; Sibillano, Teresa; De Lucia, Francesco; Dabbicco, Maurizio; Lugarà, Pietro Mario; Scamarcio, Gaetano

    2011-03-15

    We demonstrate that diode laser self-mixing interferometry can be exploited to instantaneously measure the ablation front displacement and the laser ablation rate during ultrafast microdrilling of metals. The proof of concept was obtained using a 50-μm-thick stainless steel plate as the target, a 120 ps/110 kHz microchip fiber laser as the machining source, and an 823 nm diode laser with an integrated photodiode as the probe. The time dependence of the hole penetration depth was measured with a 0.41 µm resolution.

  19. Very high resolution measurement of the penetration depth of superconductors by a novel single-coil inductance technique

    NASA Astrophysics Data System (ADS)

    Gauzzi, A.; Le Cochec, J.; Lamura, G.; Jönsson, B. J.; Gasparov, V. A.; Ladan, F. R.; Plaçais, B.; Probst, P. A.; Pavuna, D.; Bok, J.

    2000-05-01

    We describe a novel single-coil mutual inductance technique for measuring the magnetic penetration depth λ of superconductors at 2-4 MHz as a function of temperature in the 4-100 K range. We combine a single-coil configuration with a high-stability marginal oscillator; this enables us to measure the absolute value of λ on both bulk samples and thin films with very high resolution (δλ=10 pm) and a precision of 30 nm. As example of application, we report measurements on NbTi bulk samples and Nb films. This contactless technique is suited for probing the superconducting properties of samples over large surfaces.

  20. A curved detection-slit to improve ERD (Elastic Recoil Detection) energy/depth resolution

    SciTech Connect

    Brice, D.K.; Doyle, B.L.

    1989-01-01

    Recoil atoms detected in Elastic Recoil Detection (ERD) experiments emerge from an initial collision area along cones of constant energy due to the cylindrical symmetry of the elastic scattering cross section. The constant energy cones therefore intercept planar slit plates placed before the detectors in conic sections. For ease of fabrication slits are typically configured as long narrow rectangles, and as a result energy resolution is adversely affected. It has been shown that the kinematic broadening caused by using rectangular slits is minimized when L = 2 (W z tan/Theta//sub recoil/)/sup 1/2/ where W is the slit width, L is the slit length, z is the slit-target distance and /Theta//sub recoil/ is the lab-frame recoil angle. The improved energy resolution which results when rectangular slits are replaced by appropriate curved slits is examined here. Formulas are given for the conic sections associated with the curved slits as a function of experimental geometry. When slit dimensions are small compared with the full extent of the conic section slit geometry can be accurately approximated as the arc of a circle with radius R/sub c/ = z tan/Theta//sub recoil/. Energy loss effects on the resolution are also accounted for in our treatment. The use of curved slits with L = 4 (W z tan/Theta//sub recoil/)/sup 1/2/ is shown to improve kinematic broadening by /approximately/50% as compared to optimized rectangular slits of the same area. 2 refs., 5 figs.

  1. 3D silicon sensors with variable electrode depth for radiation hard high resolution particle tracking

    NASA Astrophysics Data System (ADS)

    Da Vià, C.; Borri, M.; Dalla Betta, G.; Haughton, I.; Hasi, J.; Kenney, C.; Povoli, M.; Mendicino, R.

    2015-04-01

    3D sensors, with electrodes micro-processed inside the silicon bulk using Micro-Electro-Mechanical System (MEMS) technology, were industrialized in 2012 and were installed in the first detector upgrade at the LHC, the ATLAS IBL in 2014. They are the radiation hardest sensors ever made. A new idea is now being explored to enhance the three-dimensional nature of 3D sensors by processing collecting electrodes at different depths inside the silicon bulk. This technique uses the electric field strength to suppress the charge collection effectiveness of the regions outside the p-n electrodes' overlap. Evidence of this property is supported by test beam data of irradiated and non-irradiated devices bump-bonded with pixel readout electronics and simulations. Applications include High-Luminosity Tracking in the high multiplicity LHC forward regions. This paper will describe the technical advantages of this idea and the tracking application rationale.

  2. Testing peatland water-table depth transfer functions using high-resolution hydrological monitoring data

    NASA Astrophysics Data System (ADS)

    Swindles, Graeme T.; Holden, Joseph; Raby, Cassandra L.; Turner, T. Edward; Blundell, Antony; Charman, Dan J.; Menberu, Meseret Walle; Kløve, Bjørn

    2015-07-01

    Transfer functions are now commonly used to reconstruct past environmental variability from palaeoecological data. However, such approaches need to be critically appraised. Testate amoeba-based transfer functions are an established method for the quantitative reconstruction of past water-table variations in peatlands, and have been applied to research questions in palaeoclimatology, peatland ecohydrology and archaeology. We analysed automatically-logged peatland water-table data from dipwells located in England, Wales and Finland and a suite of three year, one year and summer water-table statistics were calculated from each location. Surface moss samples were extracted from beside each dipwell and the testate amoebae community composition was determined. Two published transfer functions were applied to the testate-amoeba data for prediction of water-table depth (England and Europe). Our results show that estimated water-table depths based on the testate amoeba community reflect directional changes, but that they are poor representations of the real mean or median water-table magnitudes for the study sites. We suggest that although testate amoeba-based reconstructions can be used to identify past shifts in peat hydrology, they cannot currently be used to establish precise hydrological baselines such as those needed to inform management and restoration of peatlands. One approach to avoid confusion with contemporary water-table determinations is to use residuals or standardised values for peatland water-table reconstructions. We contend that our test of transfer functions against independent instrumental data sets may be more powerful than relying on statistical testing alone.

  3. Common-path depth-filtered digital holography for high resolution imaging of buried semiconductor structures

    NASA Astrophysics Data System (ADS)

    Finkeldey, Markus; Schellenberg, Falk; Gerhardt, Nils C.; Paar, Christof; Hofmann, Martin R.

    2016-03-01

    We investigate digital holographic microscopy (DHM) in reflection geometry for non-destructive 3D imaging of semiconductor devices. This technique provides high resolution information of the inner structure of a sample while maintaining its integrity. To illustrate the performance of the DHM, we use our setup to localize the precise spots for laser fault injection, in the security related field of side-channel attacks. While digital holographic microscopy techniques easily offer high resolution phase images of surface structures in reflection geometry, they are typically incapable to provide high quality phase images of buried structures due to the interference of reflected waves from different interfaces inside the structure. Our setup includes a sCMOS camera for image capture, arranged in a common-path interferometer to provide very high phase stability. As a proof of principle, we show sample images of the inner structure of a modern microcontroller. Finally, we compare our holographic method to classic optical beam induced current (OBIC) imaging to demonstrate its benefits.

  4. In-depth study of single photon time resolution for the Philips digital silicon photomultiplier

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Gundacker, S.; Pizzichemi, M.; Ghezzi, A.; Auffray, E.; Lecoq, P.; Paganoni, M.

    2016-06-01

    The digital silicon photomultiplier (SiPM) has been commercialised by Philips as an innovative technology compared to analog silicon photomultiplier devices. The Philips digital SiPM, has a pair of time to digital converters (TDCs) connected to 12800 single photon avalanche diodes (SPADs). Detailed measurements were performed to understand the low photon time response of the Philips digital SiPM. The single photon time resolution (SPTR) of every single SPAD in a pixel consisting of 3200 SPADs was measured and an average value of 85 ps full width at half maximum (FWHM) was observed. Each SPAD sends the signal to the TDC with different signal propagation time, resulting in a so called trigger network skew. This distribution of the trigger network skew for a pixel (3200 SPADs) has been measured and a variation of 50 ps FWHM was extracted. The SPTR of the whole pixel is the combination of SPAD jitter, trigger network skew, and the SPAD non-uniformity. The SPTR of a complete pixel was 103 ps FWHM at 3.3 V above breakdown voltage. Further, the effect of the crosstalk at a low photon level has been studied, with the two photon time resolution degrading if the events are a combination of detected (true) photons and crosstalk events. Finally, the time response to multiple photons was investigated.

  5. Multimodal adaptive optics for depth-enhanced high-resolution ophthalmic imaging

    NASA Astrophysics Data System (ADS)

    Hammer, Daniel X.; Mujat, Mircea; Iftimia, Nicusor V.; Lue, Niyom; Ferguson, R. Daniel

    2010-02-01

    We developed a multimodal adaptive optics (AO) retinal imager for diagnosis of retinal diseases, including glaucoma, diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinitis pigmentosa (RP). The development represents the first ever high performance AO system constructed that combines AO-corrected scanning laser ophthalmoscopy (SLO) and swept source Fourier domain optical coherence tomography (SSOCT) imaging modes in a single compact clinical prototype platform. The SSOCT channel operates at a wavelength of 1 μm for increased penetration and visualization of the choriocapillaris and choroid, sites of major disease activity for DR and wet AMD. The system is designed to operate on a broad clinical population with a dual deformable mirror (DM) configuration that allows simultaneous low- and high-order aberration correction. The system also includes a wide field line scanning ophthalmoscope (LSO) for initial screening, target identification, and global orientation; an integrated retinal tracker (RT) to stabilize the SLO, OCT, and LSO imaging fields in the presence of rotational eye motion; and a high-resolution LCD-based fixation target for presentation to the subject of stimuli and other visual cues. The system was tested in a limited number of human subjects without retinal disease for performance optimization and validation. The system was able to resolve and quantify cone photoreceptors across the macula to within ~0.5 deg (~100-150 μm) of the fovea, image and delineate ten retinal layers, and penetrate to resolve targets deep into the choroid. In addition to instrument hardware development, analysis algorithms were developed for efficient information extraction from clinical imaging sessions, with functionality including automated image registration, photoreceptor counting, strip and montage stitching, and segmentation. The system provides clinicians and researchers with high-resolution, high performance adaptive optics imaging to help

  6. Fine Particulate Matter Predictions Using High Resolution Aerosol Optical Depth (AOD) Retrievals

    NASA Technical Reports Server (NTRS)

    Chudnovsky, Alexandra A.; Koutrakis, Petros; Kloog, Itai; Melly, Steven; Nordio, Francesco; Lyapustin, Alexei; Wang, Jujie; Schwartz, Joel

    2014-01-01

    To date, spatial-temporal patterns of particulate matter (PM) within urban areas have primarily been examined using models. On the other hand, satellites extend spatial coverage but their spatial resolution is too coarse. In order to address this issue, here we report on spatial variability in PM levels derived from high 1 km resolution AOD product of Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm developed for MODIS satellite. We apply day-specific calibrations of AOD data to predict PM(sub 2.5) concentrations within the New England area of the United States. To improve the accuracy of our model, land use and meteorological variables were incorporated. We used inverse probability weighting (IPW) to account for nonrandom missingness of AOD and nested regions within days to capture spatial variation. With this approach we can control for the inherent day-to-day variability in the AOD-PM(sub 2.5) relationship, which depends on time-varying parameters such as particle optical properties, vertical and diurnal concentration profiles and ground surface reflectance among others. Out-of-sample "ten-fold" cross-validation was used to quantify the accuracy of model predictions. Our results show that the model-predicted PM(sub 2.5) mass concentrations are highly correlated with the actual observations, with out-of- sample R(sub 2) of 0.89. Furthermore, our study shows that the model captures the pollution levels along highways and many urban locations thereby extending our ability to investigate the spatial patterns of urban air quality, such as examining exposures in areas with high traffic. Our results also show high accuracy within the cities of Boston and New Haven thereby indicating that MAIAC data can be used to examine intra-urban exposure contrasts in PM(sub 2.5) levels.

  7. Fine particulate matter predictions using high resolution Aerosol Optical Depth (AOD) retrievals

    NASA Astrophysics Data System (ADS)

    Chudnovsky, Alexandra A.; Koutrakis, Petros; Kloog, Itai; Melly, Steven; Nordio, Francesco; Lyapustin, Alexei; Wang, Yujie; Schwartz, Joel

    2014-06-01

    To date, spatial-temporal patterns of particulate matter (PM) within urban areas have primarily been examined using models. On the other hand, satellites extend spatial coverage but their spatial resolution is too coarse. In order to address this issue, here we report on spatial variability in PM levels derived from high 1 km resolution AOD product of Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm developed for MODIS satellite. We apply day-specific calibrations of AOD data to predict PM2.5 concentrations within the New England area of the United States. To improve the accuracy of our model, land use and meteorological variables were incorporated. We used inverse probability weighting (IPW) to account for nonrandom missingness of AOD and nested regions within days to capture spatial variation. With this approach we can control for the inherent day-to-day variability in the AOD-PM2.5 relationship, which depends on time-varying parameters such as particle optical properties, vertical and diurnal concentration profiles and ground surface reflectance among others. Out-of-sample “ten-fold” cross-validation was used to quantify the accuracy of model predictions. Our results show that the model-predicted PM2.5 mass concentrations are highly correlated with the actual observations, with out-of-sample R2 of 0.89. Furthermore, our study shows that the model captures the pollution levels along highways and many urban locations thereby extending our ability to investigate the spatial patterns of urban air quality, such as examining exposures in areas with high traffic. Our results also show high accuracy within the cities of Boston and New Haven thereby indicating that MAIAC data can be used to examine intra-urban exposure contrasts in PM2.5 levels.

  8. Techniques for mass resolution improvement achieved by typical plasma mass analyzers: Modeling and simulations

    NASA Astrophysics Data System (ADS)

    Nicolaou, Georgios; Yamauchi, Masatoshi; Wieser, Martin; Barabash, Stas; Fedorov, Andrei

    2016-04-01

    Mass separation and particularly distinction between atomic ions and molecular ions are essential in understanding a wide range of plasma environments, with each consisted of different species with various properties. In this study we present the optimization results of light-weight (about 2 kg) magnetic mass analyzers with high g-factor for Rosetta (Ion Composition Analyser: ICA) and for Mars Express and Venus Express (Ion Mass Analyser: IMA). For the instrument's optimization we use SIMION, a 3D ion tracing software in which we can trace particle beams of several energies and directions, passing through the instrument's units. We first reproduced ICA and IMA results, which turned out to be different from simple models for low energy (< 100 eV). We then change the mechanical structure of several units of the instrument and we quantify the new mass resolution achieved with each change. Our goal is to find the optimal instrument's structure, which will allow us to achieve a proper mass resolution to distinguish atomic nitrogen from atomic oxygen for the purposes of a future magnetospheric mission.

  9. Soil depth map definition on a terraced slope for a following distributed, high resolution, numerical modelling analysis

    NASA Astrophysics Data System (ADS)

    Camera, C.; Apuani, T.; Mele, M.; Kuriakose, S. L.; Giudici, M.

    2012-04-01

    The soil thickness represents a key data for every environmental analysis involving soil, but its determination is not always simple. In this particular case, the study area is represented by a small terraced slope (0.6 km2) of Valtellina (Northern Italy), and the soil depth map is necessary for a coupled hydrogeological-stability analysis in a raster environment. During this work geometrical/morphological and geostatistical interpolation techniques were tested to obtain a satisfying soil depth map. At the end, the final product has been validated with geo-electrical resistivity inverse models. In this particular context, the presence of dry-stone retaining walls is of primary importance, since they have an influence on the morphology of the entire area as well as on the physical processes of water infiltration and slope stability. In order to consider the dry-stone walls in the analysis, it is necessary to have base maps with an adequate resolution (cells 1 m x 1 m). Assuming that the walls might be founded on bedrock or in its proximity, it was decided to use the heights of walls and the distribution of rock outcrops as soil depth input data. It was impossible to obtain direct measures with the knocking pole method, being pebbles frequently presents in the backfill soil . Except zero depth values, 682 measures were performed. The initial data set was divided into two subsets in order to use one as training points (76 % of the total) and the second as test points (24 %). Various techniques were tested, from linear multiple regressions with environmental predictors, to ordinary kriging, regression kriging with the same environmental variables, and Gaussian stochastic simulations. At the end, the best result was obtained with co-kriging, using a soil depth class map drawn from the field measures as co-variable. The result is a little bit guided but it was the only solution to obtain a map that partially takes into account the morphology of the slope. To verify the

  10. High Resolution Aerosol Optical Depth Mapping of Beijing Using LANSAT8 Imagery

    NASA Astrophysics Data System (ADS)

    Li, Yan; Liu, Yuanliang; Wu, Jianliang

    2016-06-01

    Aerosol Optical Depth (AOD) is one of the most important parameters in the atmospheric correction of remote sensing images. We present a new method of per pixel AOD retrieval using the imagery of Landsat8. It is based on Second Simulation of the Satellite Signal in the Solar Spectrum (6S). General dark target method takes dense vegetation pixels as dark targets and derives their 550nm AODs directly from the LUT, and interpolates the AODs of other pixels according to spatial neighbourhood using those of dark target pixels. This method will down estimate the AOD levels for urban areas. We propose an innovative method to retrieval the AODs using multiple temporal data. For a pixel which has nothing change between the associated time, there must exists an intersection of surface albedo. When there are enough data to find the intersection it ought to be a value that meet the error tolerance. In this paper, we present an example of using three temporal Landsat ETM+ image to retrieve AOD taking Beijing as the testing area. The result is compared to the commonly employed dark target algorithm to show the effectiveness of the methods.

  11. Single-pixel three-dimensional imaging with time-based depth resolution

    NASA Astrophysics Data System (ADS)

    Sun, Ming-Jie; Edgar, Matthew P.; Gibson, Graham M.; Sun, Baoqing; Radwell, Neal; Lamb, Robert; Padgett, Miles J.

    2016-07-01

    Time-of-flight three-dimensional imaging is an important tool for applications such as object recognition and remote sensing. Conventional time-of-flight three-dimensional imaging systems frequently use a raster scanned laser to measure the range of each pixel in the scene sequentially. Here we show a modified time-of-flight three-dimensional imaging system, which can use compressed sensing techniques to reduce acquisition times, whilst distributing the optical illumination over the full field of view. Our system is based on a single-pixel camera using short-pulsed structured illumination and a high-speed photodiode, and is capable of reconstructing 128 × 128-pixel resolution three-dimensional scenes to an accuracy of ~3 mm at a range of ~5 m. Furthermore, by using a compressive sampling strategy, we demonstrate continuous real-time three-dimensional video with a frame-rate up to 12 Hz. The simplicity of the system hardware could enable low-cost three-dimensional imaging devices for precision ranging at wavelengths beyond the visible spectrum.

  12. In-Depth Glycoproteomic Characterization of γ-Conglutin by High-Resolution Accurate Mass Spectrometry

    PubMed Central

    Schiarea, Silvia; Arnoldi, Lolita; Fanelli, Roberto; De Combarieu, Eric; Chiabrando, Chiara

    2013-01-01

    The molecular characterization of bioactive food components is necessary for understanding the mechanisms of their beneficial or detrimental effects on human health. This study focused on γ-conglutin, a well-known lupin seed N-glycoprotein with health-promoting properties and controversial allergenic potential. Given the importance of N-glycosylation for the functional and structural characteristics of proteins, we studied the purified protein by a mass spectrometry-based glycoproteomic approach able to identify the structure, micro-heterogeneity and attachment site of the bound N-glycan(s), and to provide extensive coverage of the protein sequence. The peptide/N-glycopeptide mixtures generated by enzymatic digestion (with or without N-deglycosylation) were analyzed by high-resolution accurate mass liquid chromatography–multi-stage mass spectrometry. The four main micro-heterogeneous variants of the single N-glycan bound to γ-conglutin were identified as Man2(Xyl) (Fuc) GlcNAc2, Man3(Xyl) (Fuc) GlcNAc2, GlcNAcMan3(Xyl) (Fuc) GlcNAc2 and GlcNAc 2Man3(Xyl) (Fuc) GlcNAc2. These carry both core β1,2-xylose and core α1-3-fucose (well known Cross-Reactive Carbohydrate Determinants), but corresponding fucose-free variants were also identified as minor components. The N-glycan was proven to reside on Asn131, one of the two potential N-glycosylation sites. The extensive coverage of the γ-conglutin amino acid sequence suggested three alternative N-termini of the small subunit, that were later confirmed by direct-infusion Orbitrap mass spectrometry analysis of the intact subunit. PMID:24069245

  13. Mapping snow-depth from manned-aircraft on landscape scales at centimeter resolution using Structure-from-Motion photogrammetry

    NASA Astrophysics Data System (ADS)

    Nolan, M.; Larsen, C. F.; Sturm, M.

    2015-01-01

    Airborne photogrammetry is undergoing a renaissance: lower-cost equipment, more powerful software, and simplified methods have significantly lowered the barriers-to-entry and now allow repeat-mapping of cryospheric dynamics at spatial resolutions and temporal frequencies that were previously too expensive to consider. Here we apply these techniques to the measurement of snow depth from manned aircraft. The main airborne hardware consists of a consumer-grade digital camera coupled to a dual-frequency GPS. The photogrammetric processing is done using a commercially-available implementation of the Structure from Motion (SfM) algorithm. The system hardware and software, exclusive of aircraft, costs less than USD 30 000. The technique creates directly-georeferenced maps without ground control, further reducing costs. To map snow depth, we made digital elevation models (DEMs) during snow-free and snow-covered conditions, then subtracted these to create difference DEMs (dDEMs). We assessed the accuracy (geolocation) and precision (repeatability) of our DEMs through comparisons to ground control points and to time-series of our own DEMs. We validated these assessments through comparisons to DEMs made by airborne lidar and by another photogrammetric system. We empirically determined an accuracy of ± 30 cm and a precision of ± 8 cm (both 95% confidence) for our methods. We then validated our dDEMs against more than 6000 hand-probed snow depth measurements at 3 test areas in Alaska covering a wide-variety of terrain and snow types. These areas ranged from 5 to 40 km2 and had ground sample distances of 6 to 20 cm. We found that depths produced from the dDEMs matched probe depths with a 10 cm standard deviation, and these depth distributions were statistically identical at 95% confidence. Due to the precision of this technique, other real changes on the ground such as frost heave, vegetative compaction by snow, and even footprints become sources of error in the measurement of

  14. Vertical and Horizontal Corneal Epithelial Thickness Profile Using Ultra-High Resolution and Long Scan Depth Optical Coherence Tomography

    PubMed Central

    Jiang, Hong; Xu, Zhe; Perez, Victor; Wang, Jianhua

    2014-01-01

    Purpose To determine the vertical and horizontal thickness profiles of the corneal epithelium in vivo using ultra-long scan depth and ultra-high resolution spectral domain optical coherence tomography (SD-OCT). Methods A SD-OCT was developed with an axial resolution of ∼3.3 µm in tissue and an extended scan depth. Forty-two eyes of 21 subjects were imaged twice. The entire horizontal and vertical corneal epithelial thickness profiles were evaluated. The coefficient of repeatability (CoR) and intraclass correlation (ICC) of the tests and interobserver variability were analyzed. Results The full width of the horizontal epithelium was detected, whereas part of the superior epithelium was not shown for the covered super eyelid. The mean central epithelial corneal thickness was 52.0±3.2 µm for the first measurement and 52.3±3.4 µm for the second measurement (P>.05). In the central zone (0–3.0 mm), the paracentral zones (3.0–6.0 mm) and the peripheral zones (6.0–10.0 mm), the mean epithelial thickness ranged from 51 to 53 µm, 52 to 57 µm, and 58 to 72 µm, respectively. There was no difference between the two tests at both meridians and in the right and left eyes (P>.05). The ICCs of the two tests ranged from 0.70 to 0.97 and the CoRs ranged from 2.5 µm to 7.8 µm from the center to the periphery, corresponding to 5.6% to 10.6% (CoR%). The ICCs of the two observers ranged from 0.72 to 0.93 and the CoRs ranged from 4.5 µm to 10.4 µm from the center to the periphery, corresponding to 8.7% to 15.2% (CoR%). Conclusions This study demonstrated good repeatability of ultra-high resolution and long scan depth SD-OCT to evaluate the entire thickness profiles of the corneal epithelium. The epithelial thickness increases from the center toward the limbus. PMID:24844566

  15. Achieving behavioral control with millisecond resolution in a high-level programming environment.

    PubMed

    Asaad, Wael F; Eskandar, Emad N

    2008-08-30

    The creation of psychophysical tasks for the behavioral neurosciences has generally relied upon low-level software running on a limited range of hardware. Despite the availability of software that allows the coding of behavioral tasks in high-level programming environments, many researchers are still reluctant to trust the temporal accuracy and resolution of programs running in such environments, especially when they run atop non-real-time operating systems. Thus, the creation of behavioral paradigms has been slowed by the intricacy of the coding required and their dissemination across labs has been hampered by the various types of hardware needed. However, we demonstrate here that, when proper measures are taken to handle the various sources of temporal error, accuracy can be achieved at the 1 ms time-scale that is relevant for the alignment of behavioral and neural events.

  16. Multistep joint bilateral depth upsampling

    NASA Astrophysics Data System (ADS)

    Riemens, A. K.; Gangwal, O. P.; Barenbrug, B.; Berretty, R.-P. M.

    2009-01-01

    Depth maps are used in many applications, e.g. 3D television, stereo matching, segmentation, etc. Often, depth maps are available at a lower resolution compared to the corresponding image data. For these applications, depth maps must be upsampled to the image resolution. Recently, joint bilateral filters are proposed to upsample depth maps in a single step. In this solution, a high-resolution output depth is computed as a weighted average of surrounding low-resolution depth values, where the weight calculation depends on spatial distance function and intensity range function on the related image data. Compared to that, we present two novel ideas. Firstly, we apply anti-alias prefiltering on the high-resolution image to derive an image at the same low resolution as the input depth map. The upsample filter uses samples from both the high-resolution and the low-resolution images in the range term of the bilateral filter. Secondly, we propose to perform the upsampling in multiple stages, refining the resolution by a factor of 2×2 at each stage. We show experimental results on the consequences of the aliasing issue, and we apply our method to two use cases: a high quality ground-truth depth map and a real-time generated depth map of lower quality. For the first use case a relatively small filter footprint is applied; the second use case benefits from a substantially larger footprint. These experiments show that the dual image resolution range function alleviates the aliasing artifacts and therefore improves the temporal stability of the output depth map. On both use cases, we achieved comparable or better image quality with respect to upsampling with the joint bilateral filter in a single step. On the former use case, we feature a reduction of a factor of 5 in computational cost, whereas on the latter use case, the cost saving is a factor of 50.

  17. Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging

    PubMed Central

    Ge, Song; Shi, Xiangyang; Baker, James R; Banaszak Holl, Mark M; Orr, Bradford G

    2009-01-01

    We present a remanence measurement method using a superconducting quantum interference device (SQUID) to detect trace amount of magnetic nanoparticles (MNPs). Based on this method, a one-dimensional scanning system was established for imaging by utilizing superparamagnetic iron oxide nanoparticles (NPs) as contrast agents. The system was calibrated with 25 nm diameter Fe2O3 NPs, and the sensitivity of the NPs was found to be 10 ng at a distance of 1.7 cm and the spatial resolution was ∼1 cm. A theoretical model of this system was developed and applied to the deconvolution of scanned images of phantoms with two NP injection spots. Using the developed SQUID system, we were able to determine not only the amount and horizontal positions of the injections, but also their depths in the phantoms. PMID:19398816

  18. Mapping snow depth from manned aircraft on landscape scales at centimeter resolution using structure-from-motion photogrammetry

    NASA Astrophysics Data System (ADS)

    Nolan, M.; Larsen, C.; Sturm, M.

    2015-08-01

    Airborne photogrammetry is undergoing a renaissance: lower-cost equipment, more powerful software, and simplified methods have significantly lowered the barriers to entry and now allow repeat mapping of cryospheric dynamics at spatial resolutions and temporal frequencies that were previously too expensive to consider. Here we apply these advancements to the measurement of snow depth from manned aircraft. Our main airborne hardware consists of a consumer-grade digital camera directly coupled to a dual-frequency GPS; no inertial motion unit (IMU) or on-board computer is required, such that system hardware and software costs less than USD 30 000, exclusive of aircraft. The photogrammetric processing is done using a commercially available implementation of the structure from motion (SfM) algorithm. The system is simple enough that it can be operated by the pilot without additional assistance and the technique creates directly georeferenced maps without ground control, further reducing overall costs. To map snow depth, we made digital elevation models (DEMs) during snow-free and snow-covered conditions, then subtracted these to create difference DEMs (dDEMs). We assessed the accuracy (real-world geolocation) and precision (repeatability) of our DEMs through comparisons to ground control points and to time series of our own DEMs. We validated these assessments through comparisons to DEMs made by airborne lidar and by a similar photogrammetric system. We empirically determined that our DEMs have a geolocation accuracy of ±30 cm and a repeatability of ±8 cm (both 95 % confidence). We then validated our dDEMs against more than 6000 hand-probed snow depth measurements at 3 separate test areas in Alaska covering a wide-variety of terrain and snow types. These areas ranged from 5 to 40 km2 and had ground sample distances of 6 to 20 cm. We found that depths produced from the dDEMs matched probe depths with a 10 cm standard deviation, and were statistically identical at 95

  19. NOTE: On the clinical spatial resolution achievable with protons and heavier charged particle radiotherapy beams

    NASA Astrophysics Data System (ADS)

    Andreo, Pedro

    2009-06-01

    The 'sub-millimetre precision' often claimed to be achievable in protons and light ion beam therapy is analysed using the Monte Carlo code SHIELD-HIT for a broad range of energies. Based on the range of possible values and uncertainties of the mean excitation energy of water and human tissues, as well as of the composition of organs and tissues, it is concluded that precision statements deserve careful reconsideration for treatment planning purposes. It is found that the range of I-values of water stated in ICRU reports 37, 49 and 73 (1984, 1993 and 2005) for the collision stopping power formulae, namely 67 eV, 75 eV and 80 eV, yields a spread of the depth of the Bragg peak of protons and heavier charged particles (carbon ions) of up to 5 or 6 mm, which is also found to be energy dependent due to other energy loss competing interaction mechanisms. The spread is similar in protons and in carbon ions having analogous practical range. Although accurate depth-dose distribution measurements in water can be used at the time of developing empirical dose calculation models, the energy dependence of the spread causes a substantial constraint. In the case of in vivo human tissues, where distribution measurements are not feasible, the problem poses a major limitation. In addition to the spread due to the currently accepted uncertainties of their I-values, a spread of the depth of the Bragg peak due to the varying compositions of soft tissues is also demonstrated, even for cases which could be considered practically identical in clinical practice. For these, the spreads found were similar to those of water or even larger, providing support to international recommendations advising that body-tissue compositions should not be given the standing of physical constants. The results show that it would be necessary to increase the margins of a clinical target volume, even in the case of a water phantom, due to an 'intrinsic basic physics uncertainty', adding to those margins usually

  20. Experimental validation of a 2D overland flow model using high resolution water depth and velocity data

    NASA Astrophysics Data System (ADS)

    Cea, L.; Legout, C.; Darboux, F.; Esteves, M.; Nord, G.

    2014-05-01

    This paper presents a validation of a two-dimensional overland flow model using empirical laboratory data. Unlike previous publications in which model performance is evaluated as the ability to predict an outlet hydrograph, we use high resolution 2D water depth and velocity data to analyze to what degree the model is able to reproduce the spatial distribution of these variables. Several overland flow conditions over two impervious surfaces of the order of one square meter with different micro and macro-roughness characteristics are studied. The first surface is a simplified representation of a sinusoidal terrain with three crests and furrows, while the second one is a mould of a real agricultural seedbed terrain. We analyze four different bed friction parameterizations and we show that the performance of formulations which consider the transition between laminar, smooth turbulent and rough turbulent flow do not improve the results obtained with Manning or Keulegan formulas for rough turbulent flow. The simulations performed show that using Keulegan formula with a physically-based definition of the bed roughness coefficient, a two-dimensional shallow water model is able to reproduce satisfactorily the flow hydrodynamics. It is shown that, even if the resolution of the topography data and numerical mesh are high enough to include all the small scale features of the bed surface, the roughness coefficient must account for the macro-roughness characteristics of the terrain in order to correctly reproduce the flow hydrodynamics.

  1. Time-resolved photoemission apparatus achieving sub-20-meV energy resolution and high stability

    SciTech Connect

    Ishida, Y.; Togashi, T.; Yamamoto, K.; Tanaka, M.; Kiss, T.; Otsu, T.; Kobayashi, Y.; Shin, S.

    2014-12-15

    The paper describes a time- and angle-resolved photoemission apparatus consisting of a hemispherical analyzer and a pulsed laser source. We demonstrate 1.48-eV pump and 5.92-eV probe measurements at the ⩾10.5-meV and ⩾240-fs resolutions by use of fairly monochromatic 170-fs pulses delivered from a regeneratively amplified Ti:sapphire laser system operating typically at 250 kHz. The apparatus is capable to resolve the optically filled superconducting peak in the unoccupied states of a cuprate superconductor, Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8+δ}. A dataset recorded on Bi(111) surface is also presented. Technical descriptions include the followings: A simple procedure to fine-tune the spatio-temporal overlap of the pump-and-probe beams and their diameters; achieving a long-term stability of the system that enables a normalization-free dataset acquisition; changing the repetition rate by utilizing acoustic optical modulator and frequency-division circuit.

  2. Bias Correction of high resolution MODIS Aerosol Optical Depth in urban areas using the Dragon AERONET Network

    NASA Astrophysics Data System (ADS)

    Malakar, N. K.; Atia, A.; Gross, B.; Moshary, F.; Ahmed, S. A.; Lary, D. J.

    2013-12-01

    Aerosol optical depth (AOD) is widely used parameter used to quantify aerosol abundance. Satellite retrievals of aerosols over land is fundamentally more complex than aerosol retrieval over oceans. Due to wide coverage and the extensive validation the Moderate Resolution Imaging Spectroradiometer (MODIS), on board the Terra and Aqua satellites is the workhorse instrument used to retrieve AOD from space. However, satellite algorithms of AOD are extremely complex and depends strongly on sun/view geometry, spectral surface albedo, aerosol model assumptions and surface heterogeneity. This issue becomes even more severe when considering the new MODIS 3 km aerosol retrieval products within version 6. To assess satellite retrievals of these high resolution 3 km products, we use the summer 2011 Dragon AERONET data to assess accuracy as well as major retrieval bias that can occur in MODIS measurements. In this study, we explore in detail the factors that can drive these biases statistically. As discussed above, our considers multiple conditions such as surface reflectivity at various wavelengths, solar and sensor zenith angles, the solar and sensor azimuth, scattering angles as well as meteorological factors and aerosol type (angstrom coefficient) etc which are used inputs are used to train neural network in regression mode to compensate for biases against the Dragon AERONET AOD values. In particular, we confirm the results of previous studies where the land cover (urban fraction) appears to be a strong factor in AOD bias and develop a NN estimator which includes land cover directly. The algorithm will be tested not only in the Baltimore/Washington area but assessed in the general North East US where urban biases in the NYC area have been previously identified.

  3. Using high-resolution satellite aerosol optical depth to estimate daily PM2.5 geographical distribution in Mexico City

    PubMed Central

    Just, Allan C.; Wright, Robert O.; Schwartz, Joel; Coull, Brent A.; Baccarelli, Andrea A.; Tellez-Rojo, Martha María; Moody, Emily; Wang, Yujie; Lyapustin, Alexei; Kloog, Itai

    2015-01-01

    Recent advances in estimating fine particle (PM2.5) ambient concentrations use daily satellite measurements of aerosol optical depth (AOD) for spatially and temporally resolved exposure estimates. Mexico City is a dense megacity that differs from other previously modeled regions in several ways: it has bright land surfaces, a distinctive climatological cycle, and an elevated semi-enclosed air basin with a unique planetary boundary layer dynamic. We extend our previous satellite methodology to the Mexico City area, a region with higher PM2.5 than most US and European urban areas. Using a novel 1 km resolution AOD product from the MODIS instrument, we constructed daily predictions across the greater Mexico City area for 2004–2014. We calibrated the association of AOD to PM2.5 daily using municipal ground monitors, land use, and meteorological features. Predictions used spatial and temporal smoothing to estimate AOD when satellite data were missing. Our model performed well, resulting in an out-of-sample cross validation R2 of 0.724. Cross-validated root mean squared prediction error (RMSPE) of the model was 5.55 μg/m3. This novel model reconstructs long- and short-term spatially resolved exposure to PM2.5 for epidemiological studies in Mexico City. PMID:26061488

  4. Using High-Resolution Satellite Aerosol Optical Depth To Estimate Daily PM2.5 Geographical Distribution in Mexico City.

    PubMed

    Just, Allan C; Wright, Robert O; Schwartz, Joel; Coull, Brent A; Baccarelli, Andrea A; Tellez-Rojo, Martha María; Moody, Emily; Wang, Yujie; Lyapustin, Alexei; Kloog, Itai

    2015-07-21

    Recent advances in estimating fine particle (PM2.5) ambient concentrations use daily satellite measurements of aerosol optical depth (AOD) for spatially and temporally resolved exposure estimates. Mexico City is a dense megacity that differs from other previously modeled regions in several ways: it has bright land surfaces, a distinctive climatological cycle, and an elevated semi-enclosed air basin with a unique planetary boundary layer dynamic. We extend our previous satellite methodology to the Mexico City area, a region with higher PM2.5 than most U.S. and European urban areas. Using a novel 1 km resolution AOD product from the MODIS instrument, we constructed daily predictions across the greater Mexico City area for 2004-2014. We calibrated the association of AOD to PM2.5 daily using municipal ground monitors, land use, and meteorological features. Predictions used spatial and temporal smoothing to estimate AOD when satellite data were missing. Our model performed well, resulting in an out-of-sample cross-validation R(2) of 0.724. Cross-validated root-mean-squared prediction error (RMSPE) of the model was 5.55 μg/m(3). This novel model reconstructs long- and short-term spatially resolved exposure to PM2.5 for epidemiological studies in Mexico City. PMID:26061488

  5. Extended depth from focus reconstruction using NIH ImageJ plugins: quality and resolution of elevation maps.

    PubMed

    Hein, Luis Rogerio De Oliveira; De Oliveira, José Alberto; De Campos, Kamila Amato; Caltabiano, Pietro Carelli Reis De Oliveira

    2012-11-01

    In this work, NIH ImageJ plugins for extended depth-from-focus reconstructions (EDFR) based on spatial domain operations were compared and tested for usage optimization. Also, some preprocessing solutions for light microscopy image stacks were evaluated, suggesting a general routine for the ImageJ user to get reliable elevation maps from grayscale image stacks. Two reflected light microscope image stacks were used to test the EDFR plugins: one bright-field image stack for the fracture of carbon-epoxy composite and its darkfield corresponding stack at same (x,y,z) spatial coordinates. Image quality analysis consisted of the comparison of signal-to-noise ratio and resolution parameters with the consistence of elevation maps, based on roughness and fractal measurements. Darkfield illumination contributed to enhance the homogeneity of images in stack and resulting height maps, reducing the influence of digital image processing choices on the dispersion of topographic measurements. The subtract background filter, as a preprocessing tool, contributed to produce sharper focused images. In general, the increasing of kernel size for EDFR spatial domain-based solutions will produce smooth height maps. Finally, this work has the main objective to establish suitable guidelines to generate elevation maps by light microscopy.

  6. Volcanic morphology of West Mata Volcano, NE Lau Basin, based on high-resolution bathymetry and depth changes

    NASA Astrophysics Data System (ADS)

    Clague, David A.; Paduan, Jennifer B.; Caress, David W.; Thomas, Hans; Chadwick, William W., Jr.; Merle, Susan G.

    2011-11-01

    High-resolution (1.5 m) mapping from the autonomous underwater vehicle (AUV) D. Allan B. of West Mata Volcano in the northern Lau Basin is used to identify the processes that construct and modify the volcano. The surface consists largely of volcaniclastic debris that forms smooth slopes to the NW and SE, with smaller lava flows forming gently sloping plateaus concentrated along the ENE and WSW rift zones, and more elongate flows radiating from the summit. Two active volcanic vents, Prometheus and Hades, are located ˜50 and ˜150 m WSW of the 1159 m summit, respectively, and are slightly NW of the ridgeline so the most abundant clastic deposits are emplaced on the NW flank. This eruptive activity and the location of vents appears to have been persistent for more than a decade, based on comparison of ship-based bathymetric surveys in 1996 and 2008-2010, which show positive depth changes up to 96 m on the summit and north flank of the volcano. The widespread distribution of clastic deposits downslope from the rift zones, as well as from the current vents, suggests that pyroclastic activity occurs at least as deep as 2200 m. The similar morphology of additional nearby volcanoes suggests that they too have abundant pyroclastic deposits.

  7. Using High-Resolution Satellite Aerosol Optical Depth To Estimate Daily PM2.5 Geographical Distribution in Mexico City.

    PubMed

    Just, Allan C; Wright, Robert O; Schwartz, Joel; Coull, Brent A; Baccarelli, Andrea A; Tellez-Rojo, Martha María; Moody, Emily; Wang, Yujie; Lyapustin, Alexei; Kloog, Itai

    2015-07-21

    Recent advances in estimating fine particle (PM2.5) ambient concentrations use daily satellite measurements of aerosol optical depth (AOD) for spatially and temporally resolved exposure estimates. Mexico City is a dense megacity that differs from other previously modeled regions in several ways: it has bright land surfaces, a distinctive climatological cycle, and an elevated semi-enclosed air basin with a unique planetary boundary layer dynamic. We extend our previous satellite methodology to the Mexico City area, a region with higher PM2.5 than most U.S. and European urban areas. Using a novel 1 km resolution AOD product from the MODIS instrument, we constructed daily predictions across the greater Mexico City area for 2004-2014. We calibrated the association of AOD to PM2.5 daily using municipal ground monitors, land use, and meteorological features. Predictions used spatial and temporal smoothing to estimate AOD when satellite data were missing. Our model performed well, resulting in an out-of-sample cross-validation R(2) of 0.724. Cross-validated root-mean-squared prediction error (RMSPE) of the model was 5.55 μg/m(3). This novel model reconstructs long- and short-term spatially resolved exposure to PM2.5 for epidemiological studies in Mexico City.

  8. Spin-flip resolution achieved with a one-proton self-excited oscillator

    NASA Astrophysics Data System (ADS)

    Guise, Nicholas Damien Sun-Wo

    In a Penning trap with an extremely large magnetic gradient, the axial frequency of a one-proton self-excited oscillator is resolved at the level of the shift from a proton spin flip. This sensitivity opens a possible path towards detection of single-proton spin flips, novel measurements of the proton and antiproton g-factors, and a stringent test of CPT invariance by comparing proton and antiproton magnetic moments at precision likely to be a million times higher than achieved to date. The central challenge of extending similar electron magnetic moment measurements to one proton is overcoming the substantially larger mass and weaker magnetic moment, which conspire to greatly reduce the frequency shift that signals a spin flip. Within a magnetic bottle gradient 50 times larger than used in the recent electron g-factor measurements, the proton spin-flip shift is still only 60 mHz out of a 553 kHz axial frequency. In such a large gradient, standard application of sideband cooling to reduce the magnetron radius changes the axial frequency by an amount greater than this spin-flip shift on average. Proton axial frequency resolution at the 60 mHz level is enabled by feedback techniques realized previously only with one electron. Self-excitation produces a narrow feature with large signal-to-noise, ideal for rapid frequency measurements at high precision. Unwanted effects of the strong magnetic gradient are minimized by axial and radial cooling. Feedback cooling is used to reduce the proton axial motion below the temperature of a damping resistor. Axial-magnetron sideband cooling of the undamped radial motion is then demonstrated to reach a 14 mK theoretical limit.

  9. 50% duty cycle may be inappropriate to achieve a sufficient chest compression depth when cardiopulmonary resuscitation is performed by female or light rescuers

    PubMed Central

    Lee, Chang Jae; Chung, Tae Nyoung; Bae, Jinkun; Kim, Eui Chung; Choi, Sung Wook; Kim, Ok Jun

    2015-01-01

    Objective Current guidelines for cardiopulmonary resuscitation recommend chest compressions (CC) during 50% of the duty cycle (DC) in part because of the ease with which individuals may learn to achieve it with practice. However, no consideration has been given to a possible interaction between DC and depth of CC, which has been the subject of recent study. Our aim was to determine if 50% DC is inappropriate to achieve sufficient chest compression depth for female and light rescuers. Methods Previously collected CC data, performed by senior medical students guided by metronome sounds with various down-stroke patterns and rates, were included in the analysis. Multiple linear regression analysis was performed to determine the association between average compression depth (ACD) with average compression rate (ACR), DC, and physical characteristics of the performers. Expected ACD was calculated for various settings. Results DC, ACR, body weight, male sex, and self-assessed physical strength were significantly associated with ACD in multivariate analysis. Based on our calculations, with 50% of DC, only men with ACR of 140/min or faster or body weight over 74 kg with ACR of 120/min can achieve sufficient ACD. Conclusion A shorter DC is independently correlated with deeper CC during simulated cardiopulmonary resuscitation. The optimal DC recommended in current guidelines may be inappropriate for achieving sufficient CD, especially for female or lighter-weight rescuers.

  10. The Impact of New York's School Libraries on Student Achievement and Motivation: Phase II--In-Depth Study

    ERIC Educational Resources Information Center

    Small, Ruth V.; Snyder, Jaime

    2009-01-01

    This article reports the results of the second phase of a three-phase study on the impact of the New York State's school libraries' services and resources on student achievement and motivation. A representative sample of more than 1,600 classroom teachers, students, and school library media specialists (SMLSs) from 47 schools throughout New York…

  11. Four-layer depth-of-interaction PET detector for high resolution PET using a multi-pixel S8550 avalanche photodiode

    NASA Astrophysics Data System (ADS)

    Nishikido, Fumihiko; Inadama, Naoko; Oda, Ichiro; Shibuya, Kengo; Yoshida, Eiji; Yamaya, Taiga; Kitamura, Keishi; Murayama, Hideo

    2010-09-01

    Avalanche photodiodes (APDs) are being used as photodetectors in positron emission tomography (PET) because they have many advantages over photomultipliers (PMTs) typically used in PET detectors. We have developed a PET detector that consists of a multi-pixel APD and a 6×6×4 array of 1.46×1.46 mm 2×4.5 m LYSO crystals for a small animal PET scanner. The detector can identify four-layer depth of interaction (DOI) with a position-sensitive APD coupled to the backside of a crystal array by just an optimized reflector arrangement. Since scintillation lights are shared among many pixels by the method, weaker signals in APD pixels far from the interacting crystals are affected by noise. To evaluate the performance of the four-layer DOI detector with the APD and the influence of electrical noise on our method, we constructed a prototype DOI detector and tested its performance. We found, except for crystal elements on the edge of the crystal array, all crystal elements could be identified from the 2D position histogram. An energy resolution of 16.9% was obtained for the whole crystal array of the APD detector. The results of noise dependence of detector performances indicated that the DOI detector using the APD could achieve sufficient performance even when using application-specific integrated circuits.

  12. Point stability at shallow depths: experience from tilt measurements in the Lower Rhine Embayment, Germany, and implications for high-resolution GPS and gravity recordings

    NASA Astrophysics Data System (ADS)

    Kümpel, H.-J.; Lehmann, K.; Fabian, M.; Mentes, Gy.

    2001-09-01

    From 1996 to 1999, we have studied ground tilts at depths of between 2m and 5m at three sites in the Lower Rhine Embayment (LRE), western Germany. The LRE is a tectonically active extensional sedimentary basin roughly 50km×100km. The purpose of the tilt measurements was (a) to provide insight into the magnitude, nature and variability of background tilts and (b) to assess possible limitations of high-resolution GPS campaigns and microgravity surveys due to natural ground deformation. The tilt readings, sensed by biaxial borehole tiltmeters of baselength 0.85m, cover a frequency range from 10-8Hz to 10-2Hz (periods from minutes to years). Assuming that the tilt signals represent ground displacements on a scale typically not larger than several times the tiltmeters' baselength, and that tilt signals at shallow depth could in a simple geometric way be related to changes in surface elevation and gravity, we try to estimate the magnitude level of point movements and corresponding Bouguer gravity effects that is generally not surpassed. The largest tilt signals observed were some +/-50µradyr-1. If they were observable over a ground section of extension, e.g. 10m, the converted rates may correspond to about +/-0.5mm per 10myr-1 in vertical ground displacement, and +/-0.1µgalyr-1 in Bouguer gravity effect, respectively. Large signals are mostly related to seasonal effects, probably linked to thermomechanical strain. Other causes of ground deformation identified include seepage effects after rainfalls (order of +/-10µrad) and diurnal strains due to thermal heating and/or fluctuations in the water consumption of nearby trees (order of +/-1µrad). Episodic step-like tilt anomalies with amplitudes up to 22µrad at one of the observation sites might reflect creep events associated to a nearby active fault. Except for short-term ground deformation caused by the passage of seismic waves from distant earthquakes, amplitudes of non-identified tilt signals in the studied

  13. Ablation depth control with 40 nm resolution on ITO thin films using a square, flat top beam shaped femtosecond NIR laser

    NASA Astrophysics Data System (ADS)

    Kim, Hoon-Young; Yoon, Ji-Wook; Choi, Won-Suk; Kim, Kwang-Ryul; Cho, Sung-Hak

    2016-09-01

    We reported on the ablation depth control with a resolution of 40 nm on indium tin oxide (ITO) thin film using a square beam shaped femtosecond (190 fs) laser (λp=1030 nm). A slit is used to make the square, flat top beam shaped from the Gaussian spatial profile of the femtosecond laser. An ablation depth of 40 nm was obtained using the single pulse irradiation at a peak intensity of 2.8 TW/cm2. The morphologies of the ablated area were characterized using an optical microscope, atomic force microscope (AFM), and energy dispersive X-ray spectroscopy (EDS). Ablations with square and rectangular types with various sizes were demonstrated on ITO thin film using slits with varying x-y axes. The stereo structure of the ablation with the depth resolution of approximately 40 nm was also fabricated successfully using the irradiation of single pulses with different shaped sizes of femtosecond laser.

  14. Looking through the haze: evaluating the CALIPSO level 2 aerosol optical depth using airborne high spectral resolution lidar data

    NASA Astrophysics Data System (ADS)

    Rogers, R. R.; Vaughan, M. A.; Hostetler, C. A.; Burton, S. P.; Ferrare, R. A.; Young, S. A.; Hair, J. W.; Obland, M. D.; Harper, D. B.; Cook, A. L.; Winker, D. M.

    2014-06-01

    The Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) instrument onboard the Cloud Aerosol Lidar and Pathfinder Satellite Observations (CALIPSO) spacecraft has provided over 8 years of nearly continuous vertical profiling of Earth's atmosphere. In this paper we investigate the CALIOP 532 nm aerosol layer optical depth (AOD) product, the AOD of individual layers, and the column AOD product, the sum AOD of the complete column, using an extensive database of coincident measurements. The CALIOP AOD measurements and AOD uncertainty estimates are compared with collocated AOD measurements collected with the NASA High Spectral Resolution Lidar (HSRL) in the North American and Caribbean regions. In addition, the CALIOP aerosol lidar ratios are investigated using the HSRL measurements. In general, compared with the HSRL values, the CALIOP layer AOD are biased high by less than 50% for AOD < 0.3 with higher errors for higher AOD. Less than 60% of the HSRL AOD measurements are encompassed within the CALIOP layer one-standard-deviation uncertainty range (around the CALIOP layer AOD), so an error estimate is created to encompass 68% of the HSRL data. Using this new metric, the CALIOP layer AOD error is estimated using the HSRL layer AOD as ± 0.035 ± 0.05 · (HSRL layer AOD) at night and ±0.05 ± 0.05 · (HSRL layer AOD) during the daytime. Furthermore, the CALIOP layer AOD error is found to correlate with aerosol loading as well as aerosol subtype, with the AODs in marine and dust layers agreeing most closely with the HSRL values. The lidar ratios used by CALIOP for polluted dust, polluted continental, and biomass burning layers are larger than the values measured by the HSRL in the CALIOP layers, and, therefore, the AODs for these types retrieved by CALIOP were generally too large. We estimated the CALIOP column AOD error can be expressed as ± 0.05 ± 0.07 · (HSRL column AOD) at night and ± 0.08 ± 0.1 · (HSRL column AOD) during the daytime. Multiple sources of

  15. Making the Library Management Systems Acquisition: Achieving Resolution of a Tough Decision.

    ERIC Educational Resources Information Center

    Bell, Steven J.; Cronin-Kardon, Cynthia

    1998-01-01

    Offers exploratory research on the automation decision process for library administrators who are considering a new library management system (LMS) and those factors that lead to decision difficulty. Using the Garbage Can Model of Organizational Choice as a theoretical framework for LMS, this study uses decision resolution as a criterion of…

  16. Application and Refinement of a Method to Achieve Uniform Convective Response on Variable-Resolution Meshes

    NASA Astrophysics Data System (ADS)

    Walko, R. L.; Medvigy, D.; Avissar, R.

    2013-12-01

    Variable-resolution computational grids can substantially improve the benefit-to-cost ratio in many environmental modeling applications, but they can also introduce unwanted and unrealistic numerical anomalies if not properly utilized. For example, we showed in previous studies that resolved (non-parameterized) atmospheric convection develops more quickly as resolution increases. Furthermore, on variable grids that transition from resolved to parameterized convection, timing and intensity of the convection in both regimes is generally disparate unless special care is taken to tune the parameterization. In both cases, the convection that develops first (due to purely numerical reasons) tends to suppress convection elsewhere by inducing subsidence in the surrounding environment. This highly nonlinear competition, while desirable when induced by natural causes such as surface inhomogeneity, is highly undesirable when it is a numerical artifact of variable grid resolution and/or selective application of convective parameterization. Our current research is aimed at leveling the playing field for convection across a variable resolution grid so that the above problems are avoided. The underlying idea is to apply the same or very similar 'convective machinery' to all areas of the grid. For convection-resolving regions of the grid, this machinery is simply the model grid itself, along with explicit representation of dynamics and a bulk microphysics parameterization. For coarser regions of the grid, the local environment is sampled from one or more grid columns (depending on local resolution) and fed to a separate 'convective processor', which determines the convective response to that environment and feeds the result back to the host grid. The convective processor chooses to either (1) explicitly resolve convective activity in the given environment on a separate (independent) limited-area 3D computational grid of comparable resolution to the convection-resolving part of the

  17. Achieving atomic resolution magnetic dichroism by controlling the phase symmetry of an electron probe

    SciTech Connect

    Rusz, Jan; Idrobo, Juan -Carlos; Bhowmick, Somnath

    2014-09-30

    The calculations presented here reveal that an electron probe carrying orbital angular momentum is just a particular case of a wider class of electron beams that can be used to measure electron magnetic circular dichroism (EMCD) with atomic resolution. It is possible to obtain an EMCD signal with atomic resolution by simply breaking the symmetry of the electron probe phase front using the aberration-corrected optics of a scanning transmission electron microscope. The probe’s required phase distribution depends on the sample’s magnetic symmetry and crystal structure. The calculations indicate that EMCD signals that use the electron probe’s phase are as strong as those obtained by nanodiffraction methods.

  18. Achieving atomic resolution magnetic dichroism by controlling the phase symmetry of an electron probe

    DOE PAGES

    Rusz, Jan; Idrobo, Juan -Carlos; Bhowmick, Somnath

    2014-09-30

    The calculations presented here reveal that an electron probe carrying orbital angular momentum is just a particular case of a wider class of electron beams that can be used to measure electron magnetic circular dichroism (EMCD) with atomic resolution. It is possible to obtain an EMCD signal with atomic resolution by simply breaking the symmetry of the electron probe phase front using the aberration-corrected optics of a scanning transmission electron microscope. The probe’s required phase distribution depends on the sample’s magnetic symmetry and crystal structure. The calculations indicate that EMCD signals that use the electron probe’s phase are as strongmore » as those obtained by nanodiffraction methods.« less

  19. Use of step scan FT-IR and multivariate curve resolution to understand aging of propellant binder as a function of depth into the polymer material.

    SciTech Connect

    Rivera, Dion Arledge; Alam, Mary Kathleen

    2003-01-01

    A sample of polymeric propellant binder was aged from 0 to 60 days at 95 C and analyzed using FT-IR step scan photoacoustic spectroscopy. This technique has the ability of to obtain spectra of the polymer as a function of depth into the polymer material. Multivariate curve resolution was applied to the spectra data obtained to extract the contributions of the aged and un-aged spectral components from the spectra. It was found that multivariate curve resolution could efficiently separate highly overlapped spectra and yielded insights into the aging process.

  20. High-depth-resolution 3-dimensional radar-imaging system based on a few-cycle W-band photonic millimeter-wave pulse generator.

    PubMed

    Tseng, Tzu-Fang; Wun, Jhih-Min; Chen, Wei; Peng, Sui-Wei; Shi, Jin-Wei; Sun, Chi-Kuang

    2013-06-17

    We demonstrate that a near-single-cycle photonic millimeter-wave short-pulse generator at W-band is capable to provide high spatial resolution three-dimensional (3-D) radar imaging. A preliminary study indicates that 3-D radar images with a state-of-the-art ranging resolution of around 1.2 cm at the W-band can be achieved.

  1. Looking through the haze: evaluating the CALIPSO level 2 aerosol optical depth using airborne high spectral resolution lidar data

    NASA Astrophysics Data System (ADS)

    Rogers, R. R.; Vaughan, M. A.; Hostetler, C. A.; Burton, S. P.; Ferrare, R. A.; Young, S. A.; Hair, J. W.; Obland, M. D.; Harper, D. B.; Cook, A. L.; Winker, D. M.

    2014-12-01

    The Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) instrument onboard the Cloud-Aerosol Lidar and Pathfinder Satellite Observations (CALIPSO) spacecraft has provided over 8 yr of nearly continuous vertical profiling of Earth's atmosphere. In this paper we investigate the V3.01 and V3.02 CALIOP 532 nm aerosol layer optical depth (AOD) product (i.e the AOD of individual layers) and the column AOD product (i.e., the sum AOD of the complete column) using an extensive database of coincident measurements. The CALIOP AOD measurements and AOD uncertainty estimates are compared with collocated AOD measurements collected with the NASA High Spectral Resolution Lidar (HSRL) in the North American and Caribbean regions. In addition, the CALIOP aerosol lidar ratios are investigated using the HSRL measurements. In general, compared with the HSRL values, the CALIOP layer AOD are biased high by less than 50% for AOD < 0.3 with higher errors for higher AOD. Less than 60% of the HSRL AOD measurements are encompassed within the CALIOP layer 1 SD uncertainty range (around the CALIOP layer AOD), so an error estimate is created to encompass 68% of the HSRL data. Using this new metric, the CALIOP layer AOD error is estimated using the HSRL layer AOD as ±0.035 ± 0.05 · (HSRL layer AOD) at night and ±0.05 ± 0.05 · (HSRL layer AOD) during the daytime. Furthermore, the CALIOP layer AOD error is found to correlate with aerosol loading as well as aerosol subtype, with the AODs in marine and dust layers agreeing most closely with the HSRL values. The lidar ratios used by CALIOP for polluted dust, polluted continental, and biomass burning layers are larger than the values measured by the HSRL in the CALIOP layers, and therefore the AODs for these types retrieved by CALIOP were generally too large. We estimated the CALIOP column AOD error can be expressed as ±0.05 ± 0.07 · (HSRL column AOD) at night and ±0.08 ± 0.1 · (HSRL column AOD) during the daytime. Multiple sources of

  2. Estimation of Basal Depth of Magnetic Sources from High Resolution Aeromagnetic Data of Middle Niger Basin, Nigeria using Adapted Centroid Technique for Fractal Distribution of Sources

    NASA Astrophysics Data System (ADS)

    Nwankwo, L.

    2015-12-01

    An estimate of depths to the bottom of magnetic sources in the Middle Niger Basin, north-central Nigeria has been made from a recently acquired high-resolution aeromagnetic data using adapted centroid technique for fractal distribution of sources. The result shows that the depth varies between 11.71 and 26.53 km. Deeper values are found in northern and central regions while values as low as 12 km were observed in the southern part. The shallower depths to the bottom of magnetic sources may be representing the thermal/petrological boundaries in the basin. This study is therefore crucial for quantitative understanding of the geo-processes and geothermal parameters in the study area.

  3. Examining Lake Michigan Spring Euphotic Depth (Zeu) Anomalies: Utilizing 10 Years of MODIS-Aqua Data at 4 Kilometer Resolution

    NASA Technical Reports Server (NTRS)

    Acker, James G.

    2013-01-01

    Examination of ten years of euphotic depth anomalies in Lake Michigan during the months of March-June indicates the following: The well-known and frequently observed occurrence of a turbidity feature in the southern part of Lake Michigan during the spring season has become less common during the period 2003-2012. Overall, the clarity of Lake Michigan water in the southern end of the lake appears to have increased spring season over the period 2003-2012. Euphotic depth can be used as a primary indicator of changes in Lake Michigan lacustrine optics, and for other large lakes. Unique events, such as the heavy rains in June 2008, can have a distinct signature in the euphotic depth anomaly distribution in Lake Michigan.

  4. Apparatus and method to achieve high-resolution microscopy with non-diffracting or refracting radiation

    SciTech Connect

    Tobin, Jr., Kenneth W.; Bingham, Philip R.; Hawari, Ayman I.

    2012-11-06

    An imaging system employing a coded aperture mask having multiple pinholes is provided. The coded aperture mask is placed at a radiation source to pass the radiation through. The radiation impinges on, and passes through an object, which alters the radiation by absorption and/or scattering. Upon passing through the object, the radiation is detected at a detector plane to form an encoded image, which includes information on the absorption and/or scattering caused by the material and structural attributes of the object. The encoded image is decoded to provide a reconstructed image of the object. Because the coded aperture mask includes multiple pinholes, the radiation intensity is greater than a comparable system employing a single pinhole, thereby enabling a higher resolution. Further, the decoding of the encoded image can be performed to generate multiple images of the object at different distances from the detector plane. Methods and programs for operating the imaging system are also disclosed.

  5. Focal plane actuation to achieve ultra-high resolution on suborbital balloon payloads

    NASA Astrophysics Data System (ADS)

    Scowen, Paul A.; Miller, Alex; Challa, Priya; Veach, Todd; Groppi, Chris; Mauskopf, Phil

    2014-07-01

    Over the past few years there has been remarkable success flying imaging telescope systems suspended from suborbital balloon payload systems. These imaging systems have covered optical, ultraviolet, sub-­-millimeter and infrared passbands (i.e. BLAST, STO, SBI, Fireball and others). In recognition of these advances NASA is now considering ambitious programs to promote planetary imaging from high altitude at a fraction of the cost of similar fully orbital systems. The challenge with imaging from a balloon payload is delivering the full diffraction-­-limited resolution of the system from a moving payload. Good progress has been made with damping mechanisms and oscillation control to remove most macroscopic movement in the departures of the imaging focal plane from a static configuration, however a jitter component remains that is difficult to remove using external corrections. This paper reports on work to demonstrate in the laboratory the utility and performance of actuating a detector focal plane (of whatever type) to remove the final jitter terms using an agile hexapod design. The input to this demonstration is the jitter signal generated by the pointing system of a previously flown balloon mission (the Stratospheric Terahertz Observatory, STO). Our group has a mature jitter compensation system that thermally isolates the control head from the focal plane itself. This allows the hexapod to remain at ambient temperature in a vacuum environment with the focal plane cooled to cryogenic temperatures. Our lab design mounts the focal plane on the hexapod in a custom cryostat and delivers an active optical stimulus together with the corresponding jitter signal, using the actuation of the hexapod to correct for the departures from a static, stable configuration. We believe this demonstration will make the case for inclusion of this technological solution in future balloon-­-borne imaging systems requiring ultra-­-high resolution.

  6. A PET detector module with monolithic crystal, single end readout, SiPM array and high depth-of-interaction resolution

    NASA Astrophysics Data System (ADS)

    Zhang, H.; Zhou, R.; Yang, C.

    2016-08-01

    Depth of interaction (DOI) technology can improve the spatial resolution of nuclear medicine imaging system which uses scintillation detectors such as Positron Emission Tomography (PET). In this paper, a prototype detector module with DOI capability is established to make complementary characteristic tests on an existing method and to improve the experimental performance using the same method. We investigate the gamma incident surface and incident angle effects on the positioning method with our model in simulations and evaluate its 3-D positioning results in experiment. It shows that the positioning results are highly affected by the gamma incident surface and incident angle. The 137Cs energy resolution is 12.1% and the DOI resolution is estimated at 2.26 mm in average by our detector in experiment.

  7. Improved mapping of flood extent and flood depth using space based SAR data in combination with very high resolution digital elevation data

    NASA Astrophysics Data System (ADS)

    Zwenzner, H.

    2009-04-01

    than a few pixels. Major causes are flooded vegetation or urban structures which lead to an underestimation of the true water level because of higher backscatter values than a plain specular water surface. Also a rough water surface caused by wind or precipitation can result in higher backscatter values and thus misclassification of land instead of water. In these cases the water level can not be retrieved in a reliable manner. In the averaged water surface of the longitudinal profile, variations in the successive water levels due to small scale thematic/geometric errors could be balanced and a smooth and more realistic water surface was generated. Subsequently, each of the cross section flood profiles were trimmed or extended according to the modified water level from the longitudinal profile, and thereby the remotely sensed flood profiles were fitted onto the underlying topography. Having achieved coherence between the water surface and the topography, the flood depth could be derived and mapped. The resulting flood extent was compared against aerial photography taken 15 hours prior to the satellite pass and showed good agreement. Finally, the performance of the matching technique and scaling effects as well as the potential and the constraints of the approach are evaluated and discussed. In this context the demand for satellite-based high resolution SAR data and high resolution elevation data are stressed. The proposed semi-automatic method has been developed in the context of the rapid mapping of flood parameters, such as flood extent and flood depth, as contribution for disaster management operations or the rapid estimation of flood damages. The requirements of such applications are fulfilled by the fact that computation time is negligible and data requirements are low, i.e. only remote sensing data and high resolution topographic data are needed. The proposed method stands in contrast to hydrological modeling approaches which are more complex with respect to data

  8. Effect of taxonomic resolution on ecological and palaeoecological inference - a test using testate amoeba water table depth transfer functions

    NASA Astrophysics Data System (ADS)

    Mitchell, Edward A. D.; Lamentowicz, Mariusz; Payne, Richard J.; Mazei, Yuri

    2014-05-01

    Sound taxonomy is a major requirement for quantitative environmental reconstruction using biological data. Transfer function performance should theoretically be expected to decrease with reduced taxonomic resolution. However for many groups of organisms taxonomy is imperfect and species level identification not always possible. We conducted numerical experiments on five testate amoeba water table (DWT) transfer function data sets. We sequentially reduced the number of taxonomic groups by successively merging morphologically similar species and removing inconspicuous species. We then assessed how these changes affected model performance and palaeoenvironmental reconstruction using two fossil data sets. Model performance decreased with decreasing taxonomic resolution, but this had only limited effects on patterns of inferred DWT, at least to detect major dry/wet shifts. Higher-resolution taxonomy may however still be useful to detect more subtle changes, or for reconstructed shifts to be significant.

  9. Interpreting 16S metagenomic data without clustering to achieve sub-OTU resolution

    PubMed Central

    Tikhonov, Mikhail; Leach, Robert W; Wingreen, Ned S

    2015-01-01

    The standard approach to analyzing 16S tag sequence data, which relies on clustering reads by sequence similarity into Operational Taxonomic Units (OTUs), underexploits the accuracy of modern sequencing technology. We present a clustering-free approach to multi-sample Illumina data sets that can identify independent bacterial subpopulations regardless of the similarity of their 16S tag sequences. Using published data from a longitudinal time-series study of human tongue microbiota, we are able to resolve within standard 97% similarity OTUs up to 20 distinct subpopulations, all ecologically distinct but with 16S tags differing by as little as one nucleotide (99.2% similarity). A comparative analysis of oral communities of two cohabiting individuals reveals that most such subpopulations are shared between the two communities at 100% sequence identity, and that dynamical similarity between subpopulations in one host is strongly predictive of dynamical similarity between the same subpopulations in the other host. Our method can also be applied to samples collected in cross-sectional studies and can be used with the 454 sequencing platform. We discuss how the sub-OTU resolution of our approach can provide new insight into factors shaping community assembly. PMID:25012900

  10. Chemical analysis of solids with sub-nm depth resolution by using a miniature LIMS system designed for in situ space research

    NASA Astrophysics Data System (ADS)

    Riedo, Andreas; Grimaudo, Valentine; Moreno-García, Pavel; Brigitte Neuland, Maike; Tulej, Marek; Broekmann, Peter; Wurz, Peter

    2015-04-01

    Sensitive elemental and isotope analysis of solid samples are of considerable interest in nowadays in situ space research. For context in situ analysis, high spatial resolution is also of substantial importance. While the measurements conducted with high lateral resolution can provide compositional details of the surface of highly heterogeneous materials, depth profiling measurements yield information on compositional details of surface and subsurface. The mass spectrometric analysis with the vertical resolution at sub-µm levels is of special consideration and can deliver important information on processes, which may have modified the surface. Information on space weathering effects can be readily determined when the sample composition of the surface and sub-surface is studied with high vertical resolution. In this contribution we will present vertical depth resolution measurements conducted by our sensitive miniature laser ablation ionization time-of-flight mass spectrometer (160mm x Ø 60mm) designed for in situ space research [1-3]. The mass spectrometer is equipped with a fs-laser system (~190fs pulse width, λ = 775nm), which is used for ablation and ionization of the sample material [2]. Laser radiation is focussed on the target material to a spot size of about 10-20 µm in diameter. Mass spectrometric measurements are conducted with a mass resolution (m/Δm) of about 400-500 (at 56Fe mass peak) and with a superior dynamic range of more than eight orders of magnitude. The depth profiling performance studies were conducted on 10µm thick Cu films that were deposited by an additive-assisted electrochemical procedure on Si-wafers. The presented measurement study will show that the current instrument prototype is able to conduct quantitative chemical (elemental and isotope) analysis of solids with a vertical resolution at sub-nm level. Contaminants, incorporated by using additives (polymers containing e.g. C, N, O, S) and with layer thickness of a few nanometres

  11. Age depth model construction of the upper section of ICDP Dead Sea Deep Drilling Project based on the high-resolution 14C dating

    NASA Astrophysics Data System (ADS)

    Kitagawa, H.; Nakamura, T.; Neugebauer, I.; Schwab, M. J.; Brauer, A.; Goldstein, S. L.; Stein, M.

    2014-12-01

    To reconstruct environmental, climatic and tectonic histories of the Levant, a deep drilling has been accomplished in the northern basin of the Dead Sea during the fall winter of 2010-2011 by the Dead Sea Deep Drilling Project (DSDDP) in the framework of the ICDP program. The sediment cores from site 5017-1 (water depth of ~300 m) recorded the paleoenvironmental and paleohydrological changes in the Dead Sea and the Levant during the last two glacial-interglacial cycles (Neugebauer et al., QSR in press). To provide precise timing of sedimentological - limnological events in the lake and its watershed, and more critically the relative timing of these events, radiocarbon dating of >70 well-preserved terrestrial plants and some carbonate deposits from the upper 150 m long section of the sediment core were performed. Based on the high-resolution radiocarbon dating, a statistical age-depth model was constructed with assumptions on the deposition condition and the radiocarbon age offset of carbonate samples. We discuss the practicality and the limitation of the age-depth model toward interpreting the high-resolution records of environmental, climatic and tectonic events recorded in the long sediment cores from site 5017-1.

  12. Depth-resolved mid-infrared photothermal imaging of living cells and organisms with submicrometer spatial resolution

    PubMed Central

    Zhang, Delong; Li, Chen; Zhang, Chi; Slipchenko, Mikhail N.; Eakins, Gregory; Cheng, Ji-Xin

    2016-01-01

    Chemical contrast has long been sought for label-free visualization of biomolecules and materials in complex living systems. Although infrared spectroscopic imaging has come a long way in this direction, it is thus far only applicable to dried tissues because of the strong infrared absorption by water. It also suffers from low spatial resolution due to long wavelengths and lacks optical sectioning capabilities. We overcome these limitations through sensing vibrational absorption–induced photothermal effect by a visible laser beam. Our mid-infrared photothermal (MIP) approach reached 10 μM detection sensitivity and submicrometer lateral spatial resolution. This performance has exceeded the diffraction limit of infrared microscopy and allowed label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells were visualized. We further demonstrated in vivo MIP imaging of lipids and proteins in Caenorhabditis elegans. The reported MIP imaging technology promises broad applications from monitoring metabolic activities to high-resolution mapping of drug molecules in living systems, which are beyond the reach of current infrared microscopy. PMID:27704043

  13. Toward improved prediction of the bedrock depth underneath hillslopes: Bayesian inference of the bottom-up control hypothesis using high-resolution topographic data

    NASA Astrophysics Data System (ADS)

    Gomes, Guilherme J. C.; Vrugt, Jasper A.; Vargas, Eurípedes A.

    2016-04-01

    The depth to bedrock controls a myriad of processes by influencing subsurface flow paths, erosion rates, soil moisture, and water uptake by plant roots. As hillslope interiors are very difficult and costly to illuminate and access, the topography of the bedrock surface is largely unknown. This essay is concerned with the prediction of spatial patterns in the depth to bedrock (DTB) using high-resolution topographic data, numerical modeling, and Bayesian analysis. Our DTB model builds on the bottom-up control on fresh-bedrock topography hypothesis of Rempe and Dietrich (2014) and includes a mass movement and bedrock-valley morphology term to extent the usefulness and general applicability of the model. We reconcile the DTB model with field observations using Bayesian analysis with the DREAM algorithm. We investigate explicitly the benefits of using spatially distributed parameter values to account implicitly, and in a relatively simple way, for rock mass heterogeneities that are very difficult, if not impossible, to characterize adequately in the field. We illustrate our method using an artificial data set of bedrock depth observations and then evaluate our DTB model with real-world data collected at the Papagaio river basin in Rio de Janeiro, Brazil. Our results demonstrate that the DTB model predicts accurately the observed bedrock depth data. The posterior mean DTB simulation is shown to be in good agreement with the measured data. The posterior prediction uncertainty of the DTB model can be propagated forward through hydromechanical models to derive probabilistic estimates of factors of safety.

  14. A BGO/GSO position sensitive block detector for a high resolution positron emission tomography with depth of interaction detection capability

    SciTech Connect

    Yamamoto, S.

    1996-12-31

    We developed a position sensitive block detector with depth of interaction detection capability for positron emission tomography (PET). The detector consists of 6 x 8 array of GSO scintillators, 6 x 8 array of BGO scintillators and two dual photomultiplier tubes (PMT). The GSO scintillators are optically coupled to front surface of the BGO scintillators. The position of 6 x 8 scintillators are determined by the Anger principle and depth of interaction position is determined by using the pulse shape analysis of GSOs and BGOs. Performance of the block detector was measured. Position distribution of the developed BGO/GSO block detector was little distorted. However the separation of the spots was still enough to distinguish the scintillators in transaxial and axial directions. Since pulse shape distribution using a developed simple pulse shape analyzer had two peaks, it is possible to separate the GSOs and BGOs for depth of interaction detection. With these results, a high resolution PET with depth of interaction detection capability will be possible using the developed BGO/GSO block detectors.

  15. Evaluation of Curie-point depths, geothermal gradients and near-surface heat flow from high-resolution aeromagnetic (HRAM) data of the entire Sokoto Basin, Nigeria

    NASA Astrophysics Data System (ADS)

    Nwankwo, Levi I.; Shehu, Amada T.

    2015-10-01

    An evaluation of Curie-point depths, geothermal gradients and near-surface heat flow has been carried out from the spectral analysis of the recently acquired high resolution aeromagnetic (HRAM) data of the entire Sokoto Basin in northwestern Nigeria. The HRAM data was divided into twenty two (22) overlapping blocks and each block analyzed using the spectral centroid method to obtain depth to the top, centroid and bottom of magnetic sources. The depth values were subsequently used to evaluate the Curie-point depth (CPD), geothermal gradient and near-surface heat flow in the study area. The result shows that the CPD varies between 11.13 and 27.83 km with an average of 18.57 km, the geothermal gradient varies between 20.84 and 52.11 °C/km with an average of 33.99 °C/km, and the resulting heat flow varies between 52.11 and 130.28 mW m- 2 with an average of 84.97 mW m- 2. Such heat flow values are suggestive of anomalous geothermal conditions and are recommended for detailed geothermal exploration in the basin.

  16. Blood microcirculation monitoring by use of spatial filtering of time-integrated speckle patterns: potentialities to improve the depth resolution

    NASA Astrophysics Data System (ADS)

    Zimnyakov, Dmitry A.; Misnin, Alexander B.

    2001-06-01

    Statistical analysis of images of time-integrated dynamic speckle patterns is considered as the tool for diagnostics and imaging of in vivo tissue dynamics such as blood microcirculation in superficial layers of human tissues and organs. Basic approach for blood microcirculation monitoring using the contrast analysis of time-averaged speckle images is known as LASCA (Laser Speckle Contrast Analysis) technique. This paper presents the modified version of LASCA, which is based on application of the localized probe light source and the spatial filtration of analyzed speckle pattern in the object plane. Being compared with classical LASCA technique, this method has the certain disadvantage as the necessity of scanning procedure to provide the reconstruction of maps of blood microcirculation parameters, but it gives the additional possibilities for the analysis of depth distributions of these parameters. Theoretical background for the depth-resolved analysis of blood microcirculation parameters on the basis of the concept of effective optical path distributions for multiply scattered probe light is considered. The effect of non-zero residual contrast even in the case of large integration times is also discussed.

  17. A quantitative study of Langmuir-Blodgett model systems by high resolution electron energy loss vibrational spectroscopy. Spectral analysis and information depth

    NASA Astrophysics Data System (ADS)

    Weitzsacker, Cara L.; Gardella, Joseph A., Jr.; Gregoire, Chantal; Pireaux, Jean-Jacques

    1995-03-01

    Langmuir Blodgett monolayers of a series of anthroyl substituted alkanoic (fatty) acid derivatives are used as model systems to study the interaction of low energy electrons with organic polymers in high resolution electron energy loss spectrometry. The variation of structure in the series effectively places the anthroyl functionality at various depths from the monolayer vacuum surface. The HREELS analysis of these systems provides a means to probe the depth dependence of vibrational energy losses. Maximum likelihood spectral restoration was used to establish more precise and energies resulting from energy loss, with comparison to infrared and Raman spectroscopic results from the compounds. These band energies were then used as initial values for curve fitting of the original data. The results of curve resolution aided in the estimation of the relative intensity of vibrational bands specific to the functional groups in the anthroyl sidechain and the aliphatic hydrocarbon backbone of the molecules in the films. By comparing vibrational intensities normalized to the elastic peak, it is shown that bands due to CH vibrations from saturated aliphatic structures are more surface sensitive than those due to aromatic structures. The comparison of the series of samples shows how the signals from aromatic structures decrease relative to aliphatic over a range of 15 A from the vacuum surface.

  18. High-resolution cellular MRI: gadolinium and iron oxide nanoparticles for in-depth dual-cell imaging of engineered tissue constructs.

    PubMed

    Di Corato, Riccardo; Gazeau, Florence; Le Visage, Catherine; Fayol, Delphine; Levitz, Pierre; Lux, François; Letourneur, Didier; Luciani, Nathalie; Tillement, Olivier; Wilhelm, Claire

    2013-09-24

    Recent advances in cell therapy and tissue engineering opened new windows for regenerative medicine, but still necessitate innovative noninvasive imaging technologies. We demonstrate that high-resolution magnetic resonance imaging (MRI) allows combining cellular-scale resolution with the ability to detect two cell types simultaneously at any tissue depth. Two contrast agents, based on iron oxide and gadolinium oxide rigid nanoplatforms, were used to "tattoo" endothelial cells and stem cells, respectively, with no impact on cell functions, including their capacity for differentiation. The labeled cells' contrast properties were optimized for simultaneous MRI detection: endothelial cells and stem cells seeded together in a polysaccharide-based scaffold material for tissue engineering appeared respectively in black and white and could be tracked, at the cellular level, both in vitro and in vivo. In addition, endothelial cells labeled with iron oxide nanoparticles could be remotely manipulated by applying a magnetic field, allowing the creation of vessel substitutes with in-depth detection of individual cellular components.

  19. High-resolution cellular MRI: gadolinium and iron oxide nanoparticles for in-depth dual-cell imaging of engineered tissue constructs.

    PubMed

    Di Corato, Riccardo; Gazeau, Florence; Le Visage, Catherine; Fayol, Delphine; Levitz, Pierre; Lux, François; Letourneur, Didier; Luciani, Nathalie; Tillement, Olivier; Wilhelm, Claire

    2013-09-24

    Recent advances in cell therapy and tissue engineering opened new windows for regenerative medicine, but still necessitate innovative noninvasive imaging technologies. We demonstrate that high-resolution magnetic resonance imaging (MRI) allows combining cellular-scale resolution with the ability to detect two cell types simultaneously at any tissue depth. Two contrast agents, based on iron oxide and gadolinium oxide rigid nanoplatforms, were used to "tattoo" endothelial cells and stem cells, respectively, with no impact on cell functions, including their capacity for differentiation. The labeled cells' contrast properties were optimized for simultaneous MRI detection: endothelial cells and stem cells seeded together in a polysaccharide-based scaffold material for tissue engineering appeared respectively in black and white and could be tracked, at the cellular level, both in vitro and in vivo. In addition, endothelial cells labeled with iron oxide nanoparticles could be remotely manipulated by applying a magnetic field, allowing the creation of vessel substitutes with in-depth detection of individual cellular components. PMID:23924160

  20. Theoretical analysis of photon noise limiting axial depth resolution for three-dimensional microscopy by incoherent structured illumination

    NASA Astrophysics Data System (ADS)

    Heidingsfelder, Philipp; Gao, Jun; Ott, Peter

    2012-10-01

    The influence of photon noise to the signal evaluation of digital microscopy using a sinusoidal fringe pattern illumination with incoherent light is shown. The signal is evaluated by calculating the contrast for every charge coupled device (CCD) pixel when the object is defocused and the fringe pattern illumination shifted by a defined phase over the sample for every z-position. Every CCD pixel gets a certain number of irradiance values for every z-position which allows calculating the contrast. The result is the focal depth response (FDR) for every pixel. The FDR is Gaussian shaped and contains the height information of the specimen in the maximum. To accelerate the signal evaluation it is common to compute a fit curve to detect the maximum of the FDR. Due to the statistical photon noise, every measured irradiance value and every computed contrast value contains an error and thus also the maximum of the three-point-Gauss-curve-fit. The error of the maximum of the three-point-Gauss-curve-fit is the uncertainty of the measured height information. A general and a simplified analytical closed form solution are derived to calculate this uncertainty. An easily manageable equation allows calculating the optimal spatial frequency for an incoherent sinusoidal fringe pattern illumination and the corresponding sampling distance.

  1. Real-time visual sensing system achieving high-speed 3D particle tracking with nanometer resolution.

    PubMed

    Cheng, Peng; Jhiang, Sissy M; Menq, Chia-Hsiang

    2013-11-01

    This paper presents a real-time visual sensing system, which is created to achieve high-speed three-dimensional (3D) motion tracking of microscopic spherical particles in aqueous solutions with nanometer resolution. The system comprises a complementary metal-oxide-semiconductor (CMOS) camera, a field programmable gate array (FPGA), and real-time image processing programs. The CMOS camera has high photosensitivity and superior SNR. It acquires images of 128×120 pixels at a frame rate of up to 10,000 frames per second (fps) under the white light illumination from a standard 100 W halogen lamp. The real-time image stream is downloaded from the camera directly to the FPGA, wherein a 3D particle-tracking algorithm is implemented to calculate the 3D positions of the target particle in real time. Two important objectives, i.e., real-time estimation of the 3D position matches the maximum frame rate of the camera and the timing of the output data stream of the system is precisely controlled, are achieved. Two sets of experiments were conducted to demonstrate the performance of the system. First, the visual sensing system was used to track the motion of a 2 μm polystyrene bead, whose motion was controlled by a three-axis piezo motion stage. The ability to track long-range motion with nanometer resolution in all three axes is demonstrated. Second, it was used to measure the Brownian motion of the 2 μm polystyrene bead, which was stabilized in aqueous solution by a laser trapping system. PMID:24216655

  2. A High-Spatial-Resolution, Localized MODIS Aerosol Optical Depth Product for Use in Air Quality Exposure Assessment During Large Wildfire Smoke Events

    NASA Astrophysics Data System (ADS)

    McCarthy, M. C.; Raffuse, S. M.; DeWinter, J. L.; Craig, K. J.; Jumbam, L. K.; Fruin, S.; Lurmann, F.

    2011-12-01

    Aerosol optical depth (AOD) has potential use for determining the intra-urban variability of airborne particulate matter exposure during wildfire events; however, the standard Moderate Resolution Imaging Spectroradiometer (MODIS) AOD products have limitations for this application. Specifically, the 10x10 km resolution is too coarse for intra-urban population exposure assessments, the assumed aerosol optical properties are not representative of biomass burning aerosol, and the cloud masking algorithm misinterprets heavy smoke as clouds. We developed a localized MODIS AOD product at 1.5 and 2.5 km resolutions and tested the performance in northern California during the 2008 wildfires. The localized product's algorithm uses local biomass burning aerosol optical properties, local surface reflectance data, and a relaxed cloud filter. During the 2008 season, persistent heavy smoke was produced over northern California and the San Joaquin Valley for over two months. As California is both highly populated and covered with a relatively dense network of ground-based aerosol monitoring stations, this event provided an excellent opportunity to develop the AOD product and test its ability to predict aerosol concentrations on the ground to assess population exposure. We will present our methodology and discuss its potential for air quality and public health applications.

  3. Quantitative comparison of contrast and imaging depth of ultrahigh-resolution optical coherence tomography images in 800–1700 nm wavelength region

    PubMed Central

    Ishida, Shutaro; Nishizawa, Norihiko

    2012-01-01

    We investigated the wavelength dependence of imaging depth and clearness of structure in ultrahigh-resolution optical coherence tomography over a wide wavelength range. We quantitatively compared the optical properties of samples using supercontinuum sources at five wavelengths, 800 nm, 1060 nm, 1300 nm, 1550 nm, and 1700 nm, with the same system architecture. For samples of industrially used homogeneous materials with low water absorption, the attenuation coefficients of the samples were fitted using Rayleigh scattering theory. We confirmed that the systems with the longer-wavelength sources had lower scattering coefficients and less dependence on the sample materials. For a biomedical sample, we observed wavelength dependence of the attenuation coefficient, which can be explained by absorption by water and hemoglobin. PMID:22312581

  4. Improved stratigraphic dating at a low accumulation Alpine ice core through laser ablation trace element profiling at sub-mm depth resolution

    NASA Astrophysics Data System (ADS)

    Bohleber, Pascal; Spaulding, Nicole; Mayewski, Paul; Sneed, Sharon; Handley, Mike; Erhardt, Tobias; Wagenbach, Dietmar

    2015-04-01

    The small scale Colle Gnifetti glacier saddle (4450 m asl, Monte Rosa region) is the only ice core drilling site in the European Alps with a net accumulation low enough to offer multi-millennia climate records. However, a robust interpretation of such long term records (i.e. mineral dust, stable water isotopes) at the Colle Gnifetti (CG) multi core array is strongly challenged by depositional noise associated with a highly irregular annual layer stratigraphy. In combination with a relatively large vertical strain rate and rapid layer thinning, annual layer counting gets increasingly ambiguous as of approximately 100 years. In addition, this prevents clear attribution of likely volcanic horizons to historical eruption dates. To improve stratigraphic dating under such intricate conditions, we deployed laser ablation (LA) ICP-MS at sub-mm sample resolution. We present here the first LA impurity profiles from a new Colle Gnifetti ice core drilled 73 m to bedrock in 2013 at a site where the net snow accumulation is around 20 cm w.e. per year. We contrast the LA signal variability (including Ca, Fe, Na) to continuous flow analyses (CFA) records at cm-resolution (Ca, Na, melt water conductivity, micro- particle) recorded over the whole core length. Of special concern are the lower 28 m to bedrock, which have been continuously profiled in LA Ca, thus offering the direct comparison of Ca-signals between CFA and LA. By this means, we first validate at upper depths LA based annual layer identification through agreement with CFA based counting efforts before demonstrating the LA based counting still works at depths where CFA derived annual layers become spurious since embedded in strong, multi-year cycles. Finally, LA ice core profiling of our CG core has potential for not only dating improvement but also reveals benefits in resolving highly thinned basal ice sections including accounting for micro-structural features such as grain boundaries.

  5. A New Hybrid Spatio-temporal Model for Estimating Daily Multi-year PM2.5 Concentrations Across Northeastern USA Using High Resolution Aerosol Optical Depth Data

    NASA Technical Reports Server (NTRS)

    Kloog, Itai; Chudnovsky, Alexandra A.; Just, Allan C.; Nordio, Francesco; Koutrakis, Petros; Coull, Brent A.; Lyapustin, Alexei; Wang, Yujie; Schwartz, Joel

    2014-01-01

    The use of satellite-based aerosol optical depth (AOD) to estimate fine particulate matter PM(sub 2.5) for epidemiology studies has increased substantially over the past few years. These recent studies often report moderate predictive power, which can generate downward bias in effect estimates. In addition, AOD measurements have only moderate spatial resolution, and have substantial missing data. We make use of recent advances in MODIS satellite data processing algorithms (Multi-Angle Implementation of Atmospheric Correction (MAIAC), which allow us to use 1 km (versus currently available 10 km) resolution AOD data.We developed and cross validated models to predict daily PM(sub 2.5) at a 1X 1 km resolution across the northeastern USA (New England, New York and New Jersey) for the years 2003-2011, allowing us to better differentiate daily and long term exposure between urban, suburban, and rural areas. Additionally, we developed an approach that allows us to generate daily high-resolution 200 m localized predictions representing deviations from the area 1 X 1 km grid predictions. We used mixed models regressing PM(sub 2.5) measurements against day-specific random intercepts, and fixed and random AOD and temperature slopes. We then use generalized additive mixed models with spatial smoothing to generate grid cell predictions when AOD was missing. Finally, to get 200 m localized predictions, we regressed the residuals from the final model for each monitor against the local spatial and temporal variables at each monitoring site. Our model performance was excellent (mean out-of-sample R(sup 2) = 0.88). The spatial and temporal components of the out-of-sample results also presented very good fits to the withheld data (R(sup 2) = 0.87, R(sup)2 = 0.87). In addition, our results revealed very little bias in the predicted concentrations (Slope of predictions versus withheld observations = 0.99). Our daily model results show high predictive accuracy at high spatial resolutions

  6. High-resolution 1050 nm spectral domain retinal optical coherence tomography at 120 kHz A-scan rate with 6.1 mm imaging depth

    PubMed Central

    An, Lin; Li, Peng; Lan, Gongpu; Malchow, Doug; Wang, Ruikang K.

    2013-01-01

    We report a newly developed high speed 1050nm spectral domain optical coherence tomography (SD-OCT) system for imaging posterior segment of human eye. The system is capable of an axial resolution at ~10 µm in air, an imaging depth of 6.1 mm in air, a system sensitivity fall-off at ~6 dB/3mm and an imaging speed of 120,000 A-scans per second. We experimentally demonstrate the system’s capability to perform phase-resolved imaging of dynamic blood flow within retina, indicating high phase stability of the SDOCT system. Finally, we show an example that uses this newly developed system to image posterior segment of human eye with a large view of view (10 × 9 mm2), providing detailed visualization of microstructural features from anterior retina to posterior choroid. The demonstrated system parameters and imaging performances are comparable to those that a typical 1 µm swept source OCT would deliver for retinal imaging. PMID:23411636

  7. Climatology of the aerosol optical depth by components from the Multiangle Imaging SpectroRadiometer (MISR) and a high-resolution chemistry transport model

    NASA Astrophysics Data System (ADS)

    Lee, H.; Kalashnikova, O. V.; Suzuki, K.; Braverman, A.; Garay, M. J.; Kahn, R. A.

    2015-12-01

    The Multi-angle Imaging SpectroRadiometer (MISR) Joint Aerosol (JOINT_AS) Level 3 product provides a global, descriptive summary of MISR Level 2 aerosol optical depth (AOD) and aerosol type information for each month between March 2000 and the present. Using Version 1 of JOINT_AS, which is based on the operational (Version 22) MISR Level 2 aerosol product, this study analyzes, for the first time, characteristics of observed and simulated distributions of AOD for three broad classes of aerosols: non-absorbing, absorbing, and non-spherical - near or downwind of their major source regions. The statistical moments (means, standard deviations, and skewnesses) and distributions of AOD by components derived from the JOINT_AS are compared with results from the SPectral RadIatioN-TrAnSport (SPRINTARS) model, a chemistry transport model (CTM) with very high spatial and temporal resolution. Overall, the AOD distributions of combined MISR aerosol types show good agreement with those from SPRINTARS. Marginal distributions of AOD for each aerosol type in both MISR and SPRINTARS show considerable high positive skewness, which indicates the importance of including extreme AOD events when comparing satellite retrievals with models. The MISR JOINT_AS product will greatly facilitate comparisons between satellite observations and model simulations of aerosols by type.

  8. Advanced Covariance-Based Stochastic Inversion and Neuro-Genetic Optimization for Rosetta CONSERT Radar Data to Improve Spatial Resolution of Multi-Fractal Depth Profiles for Cometary Nucleus

    NASA Astrophysics Data System (ADS)

    Edenhofer, Peter; Ulamec, Stephan

    2015-04-01

    The paper is devoted to results of doctoral research work at University of Bochum as applied to the radar transmission experiment CONSERT of the ESA cometary mission Rosetta. This research aims at achieving the limits of optimum spatial (and temporal) resolution for radar remote sensing by implementation of covariance informations concerned with error-balanced control as well as coherence of wave propagation effects through random composite media involved (based on Joel Franklin's approach of extended stochastic inversion). As a consequence the well-known inherent numerical instabilities of remote sensing are significantly reduced in a robust way by increasing the weight of main diagonal elements of the resulting composite matrix to be inverted with respect to off-diagonal elements following synergy relations as to the principle of correlation receiver in wireless telecommunications. It is shown that the enhancement of resolution for remote sensing holds for an integral and differential equation approach of inversion as well. In addition to that the paper presents a discussion on how the efficiency of inversion for radar data gets achieved by an overall optimization of inversion due to a novel neuro-genetic approach. Such kind of approach is in synergy with the priority research program "Organic Computing" of DFG / German Research Organization. This Neuro-Genetic Optimization (NGO) turns out, firstly, to take into account more detailed physical informations supporting further improved resolution such as the process of accretion for cometary nucleus, wave propagation effects from rough surfaces, ground clutter, nonlinear focusing, etc. as well as, secondly, to accelerate the computing process of inversion in a really significantly enhanced and fast way, e.g., enabling online-control of autonomous processes such as detection of unknown objects, navigation, etc. The paper describes in some detail how this neuro-genetic approach of optimization is incorporated into the

  9. Characterization of Soft Contact Lens Edge Fitting Using Ultra-High Resolution and Ultra-Long Scan Depth Optical Coherence Tomography

    PubMed Central

    Shen, Meixiao; Cui, Lele; Riley, Colleen; Wang, Michael R.

    2011-01-01

    Purpose. To characterize the edge fitting of soft contact lenses using ultra-high resolution optical coherence tomography (UHR-OCT) and ultra-long scan depth optical coherence tomography (UL-OCT). Methods. A total of 20 participants (11 men, 9 women; mean age, 32.3 years) were recruited. Four different types of soft contact lenses were randomly fitted to both eyes of each subject on two separate visits. After 30 minutes, the horizontal meridians of the corneal center, midperiphery, and limbus were imaged by UHR-OCT. UL-OCT imaged each lens in vitro and the ocular surface of a physical model eye. Results. Angle-edged lenses had significantly less conjunctival buildup than did round-edged lenses (P = 0.008). Limbal post-lens tear film gaps were present in 42% of the eyes, with the round-edged lenses having the most at 68%. Similarly, post-lens tear film gaps at the corneal mid-periphery were present in 47% of all eyes, with the round-edged lens having the most at 75%. Mismatches between the lens and the ocular surface were simulated based on UL-OCT images of the in vitro lenses and the model eye. The existence of tear film gaps and touching points were predicted in the simulation. Conclusions. The soft contact lens edge fitting was characterized by the conjunctival buildup and tear film gaps. Different types of contact lenses presented different levels of conjunctival buildup as well as different frequencies of tear film gaps. The findings by UHR-OCT were predicted in the simulation by UL-OCT. The application of these new technologies may open new ways of designing lenses and evaluating their fit. PMID:21372023

  10. Glider and satellite high resolution monitoring of a mesoscale eddy in the Algerian basin: effects on the mixed layer depth and biochemistry

    NASA Astrophysics Data System (ADS)

    Cotroneo, Yuri; Aulicino, Giuseppe; Ruiz, Simón; Pascual, Ananda; Budillon, Giorgio; Fusco, Giannetta; Tintoré, Joaquin

    2016-04-01

    Despite of the extensive bibliography about the circulation of the Mediterranean Sea and its sub-basins, the debate on mesoscale dynamics and its impacts on biochemical processes is still open because of their intrinsic time scales and of the difficulties in sampling. In order to clarify some of these processes, the "Algerian BAsin Circulation Unmanned Survey - ABACUS" project was proposed and realized through access to JERICO Trans National Access (TNA) infrastructures between September and December 2014. In this framework, a deep glider cruise was carried out in the area between Balearic Islands and Algerian coasts to establish an endurance line for monitoring the basin circulation. During the mission, a mesoscale eddy, identified on satellite altimetry maps, was sampled at high-spatial horizontal resolution (4 km) along its main axes and from surface to 1000 m depth. Data were collected by a Slocum glider equipped with a pumped CTD and biochemical sensors that collected about 100 complete casts inside the eddy. In order to describe the structure of the eddy, in situ data were merged with new generation remotely sensed data as daily synoptic sea surface temperature (SST) and chlorophyll concentration (Chl-a) images from MODIS satellites as well as sea surface height and geostrophic velocities from AVISO. From its origin along the Algerian coast in the eastern part of the basin, the eddy propagated to north-west at a mean speed of about 4 km/day with a mean diameter of 112/130 km, a mean elevation of 15.7 cm and clearly distinguished by the surrounding waters thanks to its higher SST and Chl-a values. Temperature and salinity values along the water column confirm the origin of the eddy from the AC showing the presence of recent Atlantic water in the surface layer and Levantine Intermediate Water (LIW) in the deeper layer. Eddy footprint is clearly evident in the multiparametric vertical sections conducted along its main axes. Deepening of temperature, salinity and

  11. High resolution depth distribution of Bacteria, Archaea, methanotrophs, and methanogens in the bulk and rhizosphere soils of a flooded rice paddy

    PubMed Central

    Lee, Hyo Jung; Jeong, Sang Eun; Kim, Pil Joo; Madsen, Eugene L.; Jeon, Che Ok

    2015-01-01

    The communities and abundances of methanotrophs and methanogens, along with the oxygen, methane, and total organic carbon (TOC) concentrations, were investigated along a depth gradient in a flooded rice paddy. Broad patterns in vertical profiles of oxygen, methane, TOC, and microbial abundances were similar in the bulk and rhizosphere soils, though methane and TOC concentrations and 16S rRNA gene copies were clearly higher in the rhizosphere soil than in the bulk soil. Oxygen concentrations decreased sharply to below detection limits at 8 mm depth. Pyrosequencing of 16S rRNA genes showed that bacterial and archaeal communities varied according to the oxic, oxic-anoxic, and anoxic zones, indicating that oxygen is a determining factor for the distribution of bacterial and archaeal communities. Aerobic methanotrophs were maximally observed near the oxic-anoxic interface, while methane, TOC, and methanogens were highest in the rhizosphere soil at 30–200 mm depth, suggesting that methane is produced mainly from organic carbon derived from rice plants and is metabolized aerobically. The relative abundances of type I methanotrophs such as Methylococcus, Methylomonas, and Methylocaldum decreased more drastically than those of type II methanotrophs (such as Methylocystis and Methylosinus) with increasing depth. Methanosaeta and Methanoregula were predominant methanogens at all depths, and the relative abundances of Methanosaeta, Methanoregula, and Methanosphaerula, and GOM_Arc_I increased with increasing depth. Based on contrasts between absolute abundances of methanogens and methanotrophs at depths sampled across rhizosphere and bulk soils (especially millimeter-scale slices at the surface), we have identified populations of methanogens (Methanosaeta, Methanoregula, Methanocella, Methanobacterium, and Methanosphaerula), and methanotrophs (Methylosarcina, Methylococcus, Methylosinus, and unclassified Methylocystaceae) that are likely physiologically active in situ. PMID

  12. PSF engineering in multifocus microscopy for increased depth volumetric imaging.

    PubMed

    Hajj, Bassam; El Beheiry, Mohamed; Dahan, Maxime

    2016-03-01

    Imaging and localizing single molecules with high accuracy in a 3D volume is a challenging task. Here we combine multifocal microscopy, a recently developed volumetric imaging technique, with point spread function engineering to achieve an increased depth for single molecule imaging. Applications in 3D single molecule localization-based super-resolution imaging is shown over an axial depth of 4 µm as well as for the tracking of diffusing beads in a fluid environment over 8 µm. PMID:27231584

  13. PSF engineering in multifocus microscopy for increased depth volumetric imaging

    PubMed Central

    Hajj, Bassam; El Beheiry, Mohamed; Dahan, Maxime

    2016-01-01

    Imaging and localizing single molecules with high accuracy in a 3D volume is a challenging task. Here we combine multifocal microscopy, a recently developed volumetric imaging technique, with point spread function engineering to achieve an increased depth for single molecule imaging. Applications in 3D single molecule localization-based super-resolution imaging is shown over an axial depth of 4 µm as well as for the tracking of diffusing beads in a fluid environment over 8 µm. PMID:27231584

  14. Testing the limits of Paleozoic chronostratigraphic correlation via high-resolution (13Ccarb) biochemostratigraphy across the Llandovery–Wenlock (Silurian) boundary: Is a unified Phanerozoic time scale achievable?

    USGS Publications Warehouse

    Cramer, Bradley D.; Loydell, David K.; Samtleben, Christian; Munnecke, Axel; Kaljo, Dimitri; Mannik, Peep; Martma, Tonu; Jeppsson, Lennart; Kleffner, Mark A.; Barrick, James E.; Johnson, Craig A.; Emsbo, Poul; Joachimski, Michael M.; Bickert, Torsten; Saltzman, Matthew R.

    2010-01-01

    The resolution and fidelity of global chronostratigraphic correlation are direct functions of the time period under consideration. By virtue of deep-ocean cores and astrochronology, the Cenozoic and Mesozoic time scales carry error bars of a few thousand years (k.y.) to a few hundred k.y. In contrast, most of the Paleozoic time scale carries error bars of plus or minus a few million years (m.y.), and chronostratigraphic control better than ??1 m.y. is considered "high resolution." The general lack of Paleozoic abyssal sediments and paucity of orbitally tuned Paleozoic data series combined with the relative incompleteness of the Paleozoic stratigraphic record have proven historically to be such an obstacle to intercontinental chronostratigraphic correlation that resolving the Paleozoic time scale to the level achieved during the Mesozoic and Cenozoic was viewed as impractical, impossible, or both. Here, we utilize integrated graptolite, conodont, and carbonate carbon isotope (??13Ccarb) data from three paleocontinents (Baltica, Avalonia, and Laurentia) to demonstrate chronostratigraphic control for upper Llando very through middle Wenlock (Telychian-Sheinwoodian, ~436-426 Ma) strata with a resolution of a few hundred k.y. The interval surrounding the base of the Wenlock Series can now be correlated globally with precision approaching 100 k.y., but some intervals (e.g., uppermost Telychian and upper Shein-woodian) are either yet to be studied in sufficient detail or do not show sufficient biologic speciation and/or extinction or carbon isotopic features to delineate such small time slices. Although producing such resolution during the Paleozoic presents an array of challenges unique to the era, we have begun to demonstrate that erecting a Paleozoic time scale comparable to that of younger eras is achievable. ?? 2010 Geological Society of America.

  15. SU-E-J-126: Respiratory Gating Quality Assurance: A Simple Method to Achieve Millisecond Temporal Resolution

    SciTech Connect

    McCabe, B; Wiersma, R

    2014-06-01

    Purpose: Low temporal latency between a gating on/off signal and a linac beam on/off during respiratory gating is critical for patient safety. Although, a measurement of temporal lag is recommended by AAPM Task Group 142 for commissioning and annual quality assurance, there currently exists no published method. Here we describe a simple, inexpensive, and reliable method to precisely measure gating lag at millisecond resolutions. Methods: A Varian Real-time Position Management™ (RPM) gating simulator with rotating disk was modified with a resistive flex sensor (Spectra Symbol) attached to the gating box platform. A photon diode was placed at machine isocenter. Output signals of the flex sensor and diode were monitored with a multichannel oscilloscope (Tektronix™ DPO3014). Qualitative inspection of the gating window/beam on synchronicity were made by setting the linac to beam on/off at end-expiration, and the oscilloscope's temporal window to 100 ms to visually examine if the on/off timing was within the recommended 100-ms tolerance. Quantitative measurements were made by saving the signal traces and analyzing in MatLab™. The on and off of the beam signal were located and compared to the expected gating window (e.g. 40% to 60%). Four gating cycles were measured and compared. Results: On a Varian TrueBeam™ STx linac with RPM gating software, the average difference in synchronicity at beam on and off for four cycles was 14 ms (3 to 30 ms) and 11 ms (2 to 32 ms), respectively. For a Varian Clinac™ 21EX the average difference at beam on and off was 127 ms (122 to 133 ms) and 46 ms (42 to 49 ms), respectively. The uncertainty in the synchrony difference was estimated at ±6 ms. Conclusion: This new gating QA method is easy to implement and allows for fast qualitative inspection and quantitative measurements for commissioning and TG-142 annual QA measurements.

  16. Development and Applications of Time of Flight Neutron Depth Profiling

    SciTech Connect

    Bingham Cady; Kenan Unlu

    2005-03-17

    The depth profiles of intentional or intrinsic constituents of a sample provide valuable information for the characterization of materials. For example, the subtle differences in spatial distribution and composition of many chemical species in the near surface region and across interfacial boundaries can significantly alter the electronic and optical properties of materials. A number of analytical techniques for depth profiling have been developed during the last two decades. neutron Depth Profiling (NDP) is one of the leading analytical techniques. The NDP is a nondestructive near surface technique that utilizes thermal/cold neutron beam to measure the concentration of specific light elements versus their depth in materials. The depth is obtained from the energy loss of protons, alphas or recoil atoms in substrate materials. Since the charged particle energy determination using surface barrier detector is used for NDP, the depth resolution is highly dependent on the detectors an d detection instruments. The depth resolutions of a few tens of nm are achieved with available NDP facilities in the world. However, the performance of NDP needs to be improved in order to obtain a few A depth resolutions.

  17. Apparent Depth.

    ERIC Educational Resources Information Center

    Nassar, Antonio B.

    1994-01-01

    Discusses a well-known optical refraction problem where the depth of an object in a liquid is determined. Proposes that many texts incorrectly solve the problem. Provides theory, equations, and diagrams. (MVL)

  18. Static stereo vision depth distortions in teleoperation

    NASA Technical Reports Server (NTRS)

    Diner, D. B.; Von Sydow, M.

    1988-01-01

    A major problem in high-precision teleoperation is the high-resolution presentation of depth information. Stereo television has so far proved to be only a partial solution, due to an inherent trade-off among depth resolution, depth distortion and the alignment of the stereo image pair. Converged cameras can guarantee image alignment but suffer significant depth distortion when configured for high depth resolution. Moving the stereo camera rig to scan the work space further distorts depth. The 'dynamic' (camera-motion induced) depth distortion problem was solved by Diner and Von Sydow (1987), who have quantified the 'static' (camera-configuration induced) depth distortion. In this paper, a stereo image presentation technique which yields aligned images, high depth resolution and low depth distortion is demonstrated, thus solving the trade-off problem.

  19. Depth sensitive oblique polarized reflectance spectroscopy of oral epithelial tissue

    NASA Astrophysics Data System (ADS)

    Jimenez, Maria K.; Lam, Sylvia; Poh, Catherine; Sokolov, Konstantin

    2014-05-01

    Identifying depth-dependent alterations associated with epithelial cancerous lesions can be challenging in the oral cavity where variable epithelial thicknesses and troublesome keratin growths are prominent. Spectroscopic methods with enhanced depth resolution would immensely aid in isolating optical properties associated with malignant transformation. Combining multiple beveled fibers, oblique collection geometry, and polarization gating, oblique polarized reflectance spectroscopy (OPRS) achieves depth sensitive detection. We report promising results from a clinical trial of patients with oral lesions suspected of dysplasia or carcinoma demonstrating the potential of OPRS for the analysis of morphological and architectural changes in the context of multilayer, epithelial oral tissue.

  20. Depth and orientational dependencies of MRI T(2) and T(1ρ) sensitivities towards trypsin degradation and Gd-DTPA(2-) presence in articular cartilage at microscopic resolution.

    PubMed

    Wang, Nian; Xia, Yang

    2012-04-01

    Depth and orientational dependencies of microscopic magnetic resonance imaging (MRI) T(2) and T(1ρ) sensitivities were studied in native and trypsin-degraded articular cartilage before and after being soaked in 1 mM Gd-DTPA(2-) solution. When the cartilage surface was perpendicular to B(0), a typical laminar appearance was visible in T(2)-weighted images but not in T(1ρ)-weighted images, especially when the spin-lock field was high (2 kHz). At the magic angle (55°) orientation, neither T(2)- nor T(1ρ)-weighted image had a laminar appearance. Trypsin degradation caused a depth- and orientational-dependent T(2) increase (4%-64%) and a more uniform T(1ρ) increase at a sufficiently high spin-lock field (55%-81%). The presence of the Gd ions caused both T(2) and T(1ρ) to decrease significantly in the degraded tissue (6%-38% and 44%-49%, respectively) but less notably in the native tissue (5%-10% and 16%-28%, respectively). A quantity Sensitivity was introduced that combined both the percentage change and the absolute change in the relaxation analysis. An MRI experimental protocol based on two T(1ρ) measurements (without and with the presence of the Gd ions) was proposed to be a new imaging marker for cartilage degradation.

  1. Experimental study of the maximum resolution and packing density achievable in sintered and non-sintered binder-jet 3D printed steel microchannels

    SciTech Connect

    Elliott, Amy M; Mehdizadeh Momen, Ayyoub; Benedict, Michael; Kiggans Jr, James O

    2015-01-01

    Developing high resolution 3D printed metallic microchannels is a challenge especially when there is an essential need for high packing density of the primary material. While high packing density could be achieved by heating the structure to the sintering temperature, some heat sensitive applications require other strategies to improve the packing density of primary materials. In this study the goal is to develop high green or pack densities microchannels on the scale of 2-300 microns which have a robust mechanical structure. Binder-jet 3D printing is an additive manufacturing process in which droplets of binder are deposited via inkjet into a bed of powder. By repeatedly spreading thin layers of powder and depositing binder into the appropriate 2D profiles, complex 3D objects can be created one layer at time. Microchannels with features on the order of 500 microns were fabricated via binder jetting of steel powder and then sintered and/or infiltrated with a secondary material. The average particle size of the steel powder was varied along with the droplet volume of the inkjet-deposited binder. The resolution of the process, packing density of the primary material, the subsequent features sizes of the microchannels, and the overall microchannel quality were characterized as a function of particle size distribution, droplet sizes and heat treatment temperatures.

  2. High-resolution delineation of chlorinated volatile organic compounds in a dipping, fractured mudstone: Depth- and strata-dependent spatial variability from rock-core sampling.

    PubMed

    Goode, Daniel J; Imbrigiotta, Thomas E; Lacombe, Pierre J

    2014-12-15

    Synthesis of rock-core sampling and chlorinated volatile organic compound (CVOC) analysis at five coreholes, with hydraulic and water-quality monitoring and a detailed hydrogeologic framework, was used to characterize the fine-scale distribution of CVOCs in dipping, fractured mudstones of the Lockatong Formation of Triassic age, of the Newark Basin in West Trenton, New Jersey. From these results, a refined conceptual model for more than 55years of migration of CVOCs and depth- and strata-dependent rock-matrix contamination was developed. Industrial use of trichloroethene (TCE) at the former Naval Air Warfare Center (NAWC) from 1953 to 1995 resulted in dense non-aqueous phase liquid (DNAPL) TCE and dissolved TCE and related breakdown products, including other CVOCs, in underlying mudstones. Shallow highly weathered and fractured strata overlie unweathered, gently dipping, fractured strata that become progressively less fractured with depth. The unweathered lithology includes black highly fractured (fissile) carbon-rich strata, gray mildly fractured thinly layered (laminated) strata, and light-gray weakly fractured massive strata. CVOC concentrations in water samples pumped from the shallow weathered and highly fractured strata remain elevated near residual DNAPL TCE, but dilution by uncontaminated recharge, and other natural and engineered attenuation processes, have substantially reduced concentrations along flow paths removed from sources and residual DNAPL. CVOCs also were detected in most rock-core samples in source areas in shallow wells. In many locations, lower aqueous concentrations, compared to rock core concentrations, suggest that CVOCs are presently back-diffusing from the rock matrix. Below the weathered and highly fractured strata, and to depths of at least 50 meters (m), groundwater flow and contaminant transport is primarily in bedding-plane-oriented fractures in thin fissile high-carbon strata, and in fractured, laminated strata of the gently

  3. High-resolution delineation of chlorinated volatile organic compounds in a dipping, fractured mudstone: Depth- and strata-dependent spatial variability from rock-core sampling

    NASA Astrophysics Data System (ADS)

    Goode, Daniel J.; Imbrigiotta, Thomas E.; Lacombe, Pierre J.

    2014-12-01

    Synthesis of rock-core sampling and chlorinated volatile organic compound (CVOC) analysis at five coreholes, with hydraulic and water-quality monitoring and a detailed hydrogeologic framework, was used to characterize the fine-scale distribution of CVOCs in dipping, fractured mudstones of the Lockatong Formation of Triassic age, of the Newark Basin in West Trenton, New Jersey. From these results, a refined conceptual model for more than 55 years of migration of CVOCs and depth- and strata-dependent rock-matrix contamination was developed. Industrial use of trichloroethene (TCE) at the former Naval Air Warfare Center (NAWC) from 1953 to 1995 resulted in dense non-aqueous phase liquid (DNAPL) TCE and dissolved TCE and related breakdown products, including other CVOCs, in underlying mudstones. Shallow highly weathered and fractured strata overlie unweathered, gently dipping, fractured strata that become progressively less fractured with depth. The unweathered lithology includes black highly fractured (fissile) carbon-rich strata, gray mildly fractured thinly layered (laminated) strata, and light-gray weakly fractured massive strata. CVOC concentrations in water samples pumped from the shallow weathered and highly fractured strata remain elevated near residual DNAPL TCE, but dilution by uncontaminated recharge, and other natural and engineered attenuation processes, have substantially reduced concentrations along flow paths removed from sources and residual DNAPL. CVOCs also were detected in most rock-core samples in source areas in shallow wells. In many locations, lower aqueous concentrations, compared to rock core concentrations, suggest that CVOCs are presently back-diffusing from the rock matrix. Below the weathered and highly fractured strata, and to depths of at least 50 meters (m), groundwater flow and contaminant transport is primarily in bedding-plane-oriented fractures in thin fissile high-carbon strata, and in fractured, laminated strata of the gently

  4. High-resolution delineation of chlorinated volatile organic compounds in a dipping, fractured mudstone: depth- and strata-dependent spatial variability from rock-core sampling

    USGS Publications Warehouse

    Goode, Daniel J.; Imbrigiotta, Thomas E.; Lacombe, Pierre J.

    2014-01-01

    Synthesis of rock-core sampling and chlorinated volatile organic compound (CVOC) analysis at five coreholes, with hydraulic and water-quality monitoring and a detailed hydrogeologic framework, was used to characterize the fine-scale distribution of CVOCs in dipping, fractured mudstones of the Lockatong Formation of Triassic age, of the Newark Basin in West Trenton, New Jersey. From these results, a refined conceptual model for more than 55 years of migration of CVOCs and depth- and strata-dependent rock-matrix contamination was developed. Industrial use of trichloroethene (TCE) at the former Naval Air Warfare Center (NAWC) from 1953 to 1995 resulted in dense non-aqueous phase liquid (DNAPL) TCE and dissolved TCE and related breakdown products, including other CVOCs, in underlying mudstones. Shallow highly weathered and fractured strata overlie unweathered, gently dipping, fractured strata that become progressively less fractured with depth. The unweathered lithology includes black highly fractured (fissile) carbon-rich strata, gray mildly fractured thinly layered (laminated) strata, and light-gray weakly fractured massive strata. CVOC concentrations in water samples pumped from the shallow weathered and highly fractured strata remain elevated near residual DNAPL TCE, but dilution by uncontaminated recharge, and other natural and engineered attenuation processes, have substantially reduced concentrations along flow paths removed from sources and residual DNAPL. CVOCs also were detected in most rock-core samples in source areas in shallow wells. In many locations, lower aqueous concentrations, compared to rock core concentrations, suggest that CVOCs are presently back-diffusing from the rock matrix. Below the weathered and highly fractured strata, and to depths of at least 50 meters (m), groundwater flow and contaminant transport is primarily in bedding-plane-oriented fractures in thin fissile high-carbon strata, and in fractured, laminated strata of the gently

  5. High-resolution delineation of chlorinated volatile organic compounds in a dipping, fractured mudstone: Depth- and strata-dependent spatial variability from rock-core sampling.

    PubMed

    Goode, Daniel J; Imbrigiotta, Thomas E; Lacombe, Pierre J

    2014-12-15

    Synthesis of rock-core sampling and chlorinated volatile organic compound (CVOC) analysis at five coreholes, with hydraulic and water-quality monitoring and a detailed hydrogeologic framework, was used to characterize the fine-scale distribution of CVOCs in dipping, fractured mudstones of the Lockatong Formation of Triassic age, of the Newark Basin in West Trenton, New Jersey. From these results, a refined conceptual model for more than 55years of migration of CVOCs and depth- and strata-dependent rock-matrix contamination was developed. Industrial use of trichloroethene (TCE) at the former Naval Air Warfare Center (NAWC) from 1953 to 1995 resulted in dense non-aqueous phase liquid (DNAPL) TCE and dissolved TCE and related breakdown products, including other CVOCs, in underlying mudstones. Shallow highly weathered and fractured strata overlie unweathered, gently dipping, fractured strata that become progressively less fractured with depth. The unweathered lithology includes black highly fractured (fissile) carbon-rich strata, gray mildly fractured thinly layered (laminated) strata, and light-gray weakly fractured massive strata. CVOC concentrations in water samples pumped from the shallow weathered and highly fractured strata remain elevated near residual DNAPL TCE, but dilution by uncontaminated recharge, and other natural and engineered attenuation processes, have substantially reduced concentrations along flow paths removed from sources and residual DNAPL. CVOCs also were detected in most rock-core samples in source areas in shallow wells. In many locations, lower aqueous concentrations, compared to rock core concentrations, suggest that CVOCs are presently back-diffusing from the rock matrix. Below the weathered and highly fractured strata, and to depths of at least 50 meters (m), groundwater flow and contaminant transport is primarily in bedding-plane-oriented fractures in thin fissile high-carbon strata, and in fractured, laminated strata of the gently

  6. Glider and satellite high resolution monitoring of a mesoscale eddy in the algerian basin: Effects on the mixed layer depth and biochemistry

    NASA Astrophysics Data System (ADS)

    Cotroneo, Yuri; Aulicino, Giuseppe; Ruiz, Simón; Pascual, Ananda; Budillon, Giorgio; Fusco, Giannetta; Tintoré, Joaqun

    2016-10-01

    Deepening of temperature, salinity and density isolines at the center of the eddy is associated with variations in Chl-a, oxygen concentration and turbidity patterns. In particular, at 50 m depth along the eddy borders, Chl-a values are higher (1.1-5.2 μg/l) in comparison with the eddy center (0.5-0.7 μg/l) with maximum values found in the southeastern sector of the eddy. Calculation of geostrophic velocities along transects and vertical quasi-geostrophic velocities (QG-w) over a regular 5 km grid from the glider data helped to describe the mechanisms and functioning of the eddy. QG-w presents an asymmetric pattern, with relatively strong downwelling in the western part of the eddy and upwelling in the southeastern part. This asymmetry in the vertical velocity pattern, which brings LIW into the euphotic layer as well as advection from the northeastern sector of the eddy, may explain the observed increases in Chl-a values.

  7. Stereo depth distortions in teleoperation

    NASA Technical Reports Server (NTRS)

    Diner, Daniel B.; Vonsydow, Marika

    1988-01-01

    In teleoperation, a typical application of stereo vision is to view a work space located short distances (1 to 3m) in front of the cameras. The work presented here treats converged camera placement and studies the effects of intercamera distance, camera-to-object viewing distance, and focal length of the camera lenses on both stereo depth resolution and stereo depth distortion. While viewing the fronto-parallel plane 1.4 m in front of the cameras, depth errors are measured on the order of 2cm. A geometric analysis was made of the distortion of the fronto-parallel plane of divergence for stereo TV viewing. The results of the analysis were then verified experimentally. The objective was to determine the optimal camera configuration which gave high stereo depth resolution while minimizing stereo depth distortion. It is found that for converged cameras at a fixed camera-to-object viewing distance, larger intercamera distances allow higher depth resolutions, but cause greater depth distortions. Thus with larger intercamera distances, operators will make greater depth errors (because of the greater distortions), but will be more certain that they are not errors (because of the higher resolution).

  8. Resolution enhancement in tilted coordinates

    NASA Astrophysics Data System (ADS)

    Hariri Naghadeh, Diako; Keith Morley, Christopher

    2016-11-01

    Deconvolution is applied to remove source wavelet effects from seismograms. The results are resolution enhancement that enables detection of thin layers. Following enhancement of resolution, low frequency and high angle reflectors, particularly at great depth, appear as low amplitude and semi-invisible reflectors that are difficult to track and pick. A new approach to enhance resolution is introduced that estimates a derivative using continuous wavelet transform in tilted coordinates. The results are compared with sparse spike deconvolution, curvelet deconvolution and inverse quality filtering in wavelet domain. The positive consequence of the new method is to increase sampling of high dip features by changing the coordinate system from Cartesian to tilted. To compare those methods a complex data set was chosen that includes high angle faults and chaotic mass transport complex. Image enhancement using curvelet deconvolution shows a chaotic system as a non-chaotic one. The results show that sparse spike deconvolution and inverse quality filtering in wavelet domain are able to enhance resolution more than curvelet deconvolution especially at great depth but it is impossible to follow steep dip reflectors after resolution enhancement using these methods, especially when their apparent dips are more than 45°. By estimating derivatives in a continuous wavelet transform from tilted data sets similar resolution enhancement as the other deconvolution methods is achieved but additionally steep dipping reflectors are imaged much better than others. Subtracted results of the enhanced resolution data set using new method and the other introduced methods show that steeply dipping reflectors are highlighted as a particular ability of the new method. The results show that high frequency recovery in Cartesian co-ordinate is accompanied by inability to image steeply dipping reflectors especially at great depths. Conversely recovery of high frequency data and imaging of the data

  9. Achieving high-resolution soft-tissue imaging with cone-beam CT: a two-pronged approach for modulation of x-ray fluence and detector gain

    NASA Astrophysics Data System (ADS)

    Graham, S. A.; Siewerdsen, J. H.; Moseley, D. J.; Keller, H.; Shkumat, N. A.; Jaffray, D. A.

    2005-04-01

    Cone-beam computed tomography (CBCT) presents a highly promising and challenging advanced application of flat-panel detectors (FPDs). The great advantage of this adaptable technology is in the potential for sub-mm 3D spatial resolution in combination with soft-tissue detectability. While the former is achieved naturally by CBCT systems incorporating modern FPD designs (e.g., 200 - 400 um pixel pitch), the latter presents a significant challenge due to limitations in FPD dynamic range, large field of view, and elevated levels of x-ray scatter in typical CBCT configurations. We are investigating a two-pronged strategy to maximizing soft-tissue detectability in CBCT: 1) front-end solutions, including novel beam modulation designs (viz., spatially varying compensators) that alleviate detector dynamic range requirements, reduce x-ray scatter, and better distribute imaging dose in a manner suited to soft-tissue visualization throughout the field of view; and 2) back-end solutions, including implementation of an advanced FPD design (Varian PaxScan 4030CB) that features dual-gain and dynamic gain switching that effectively extends detector dynamic range to 18 bits. These strategies are explored quantitatively on CBCT imaging platforms developed in our laboratory, including a dedicated CBCT bench and a mobile isocentric C-arm (Siemens PowerMobil). Pre-clinical evaluation of improved soft-tissue visibility was carried out in phantom and patient imaging with the C-arm device. Incorporation of these strategies begin to reveal the full potential of CBCT for soft-tissue visualization, an essential step in realizing broad utility of this adaptable technology for diagnostic and image-guided procedures.

  10. Extended depth of field imaging for high speed object analysis

    NASA Technical Reports Server (NTRS)

    Ortyn, William (Inventor); Basiji, David (Inventor); Frost, Keith (Inventor); Liang, Luchuan (Inventor); Bauer, Richard (Inventor); Hall, Brian (Inventor); Perry, David (Inventor)

    2011-01-01

    A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element.

  11. Optimizing depth estimates from magnetic anomalies using spatial analysis tools

    NASA Astrophysics Data System (ADS)

    Curto, Julia B.; Diniz, Tatiana; Vidotti, Roberta M.; Blakely, Richard J.; Fuck, Reinhardt A.

    2015-11-01

    We offer a methodology to analyze the spatial and statistical properties of the tilt derivative of magnetic anomalies, thus facilitating the mapping of the location and depth of concealed magnetic sources. This methodology uses commonly available graphical information system (GIS) software to estimate and interpolate horizontal distances between key attributes of the tilt derivative, which then are used to estimate depth and location of causative bodies. Application of the method to synthetic data illustrates its reliability to determine depths to magnetic contacts. We also achieved consistent depth results using real data from the northwest portion of the Paraná Basin, Brazil, where magnetic anomaly interpretations are complicated by low geomagnetic inclinations and rocks with remanent magnetization. The tilt-derivative method provides more continuous and higher resolution contact information than the 3D Euler deconvolution technique.

  12. Depth perception in autostereograms: 1/f noise is best

    NASA Astrophysics Data System (ADS)

    Yankelevsky, Yael; Shvartz, Ishai; Avraham, Tamar; Bruckstein, Alfred M.

    2016-02-01

    An autostereogram is a single image that encodes depth information that pops out when looking at it. The trick is achieved by replicating a vertical strip that sets a basic two-dimensional pattern with disparity shifts that encode a three-dimensional scene. It is of interest to explore the dependency between the ease of perceiving depth in autostereograms and the choice of the basic pattern used for generating them. In this work we confirm a theory proposed by Bruckstein et al. to explain the process of autostereographic depth perception, providing a measure for the ease of "locking into" the depth profile, based on the spectral properties of the basic pattern used. We report the results of three sets of psychophysical experiments using autostereograms generated from two-dimensional random noise patterns having power spectra of the form $1/f^\\beta$. The experiments were designed to test the ability of human subjects to identify smooth, low resolution surfaces, as well as detail, in the form of higher resolution objects in the depth profile, and to determine limits in identifying small objects as a function of their size. In accordance with the theory, we discover a significant advantage of the $1/f$ noise pattern (pink noise) for fast depth lock-in and fine detail detection, showing that such patterns are optimal choices for autostereogram design. Validating the theoretical model predictions strengthens its underlying assumptions, and contributes to a better understanding of the visual system's binocular disparity mechanisms.

  13. A resolution commending the achievements and recognizing the importance of the Alliance to Save Energy on the 35th anniversary of the incorporation of the Alliance.

    THOMAS, 112th Congress

    Sen. Warner, Mark R. [D-VA

    2012-03-26

    04/18/2012 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S2517) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  14. Fast planar segmentation of depth images

    NASA Astrophysics Data System (ADS)

    Javan Hemmat, Hani; Pourtaherian, Arash; Bondarev, Egor; de With, Peter H. N.

    2015-03-01

    One of the major challenges for applications dealing with the 3D concept is the real-time execution of the algorithms. Besides this, for the indoor environments, perceiving the geometry of surrounding structures plays a prominent role in terms of application performance. Since indoor structures mainly consist of planar surfaces, fast and accurate detection of such features has a crucial impact on quality and functionality of the 3D applications, e.g. decreasing model size (decimation), enhancing localization, mapping, and semantic reconstruction. The available planar-segmentation algorithms are mostly developed using surface normals and/or curvatures. Therefore, they are computationally expensive and challenging for real-time performance. In this paper, we introduce a fast planar-segmentation method for depth images avoiding surface normal calculations. Firstly, the proposed method searches for 3D edges in a depth image and finds the lines between identified edges. Secondly, it merges all the points on each pair of intersecting lines into a plane. Finally, various enhancements (e.g. filtering) are applied to improve the segmentation quality. The proposed algorithm is capable of handling VGA-resolution depth images at a 6 FPS frame-rate with a single-thread implementation. Furthermore, due to the multi-threaded design of the algorithm, we achieve a factor of 10 speedup by deploying a GPU implementation.

  15. Validation of MODIS Aerosol Optical Depth Retrieval Over Land

    NASA Technical Reports Server (NTRS)

    Chu, D. A.; Kaufman, Y. J.; Ichoku, C.; Remer, L. A.; Tanre, D.; Holben, B. N.; Einaudi, Franco (Technical Monitor)

    2001-01-01

    Aerosol optical depths are derived operationally for the first time over land in the visible wavelengths by MODIS (Moderate Resolution Imaging Spectroradiometer) onboard the EOSTerra spacecraft. More than 300 Sun photometer data points from more than 30 AERONET (Aerosol Robotic Network) sites globally were used in validating the aerosol optical depths obtained during July - September 2000. Excellent agreement is found with retrieval errors within (Delta)tau=+/- 0.05 +/- 0.20 tau, as predicted, over (partially) vegetated surfaces, consistent with pre-launch theoretical analysis and aircraft field experiments. In coastal and semi-arid regions larger errors are caused predominantly by the uncertainty in evaluating the surface reflectance. The excellent fit was achieved despite the ongoing improvements in instrument characterization and calibration. This results show that MODIS-derived aerosol optical depths can be used quantitatively in many applications with cautions for residual clouds, snow/ice, and water contamination.

  16. The relation between Moderate Resolution Imaging Spectroradiometer (MODIS) aerosol optical depth and PM2.5 over the United States: a geographical comparison by U.S. Environmental Protection Agency regions.

    PubMed

    Zhang, Hai; Hoff, Raymond M; Engel-Cox, Jill A

    2009-11-01

    Aerosol optical depth (AOD) acquired from satellite measurements demonstrates good correlation with particulate matter with diameters less than 2.5 microm (PM2.5) in some regions of the United States and has been used for monitoring and nowcasting air quality over the United States. This work investigates the relation between Moderate Resolution Imaging Spectroradiometer (MODIS) AOD and PM2.5 over the 10 U.S. Environmental Protection Agency (EPA)-defined geographic regions in the United States on the basis of a 2-yr (2005-2006) match-up dataset of MODIS AOD and hourly PM2.5 measurements. The AOD retrievals demonstrate a geographical and seasonal variation in their relation with PM2.5. Good correlations are mostly observed over the eastern United States in summer and fall. The southeastern United States has the highest correlation coefficients at more than 0.6. The southwestern United States has the lowest correlation coefficient of approximately 0.2. The seasonal regression relations derived for each region are used to estimate the PM2.5 from AOD retrievals, and it is shown that the estimation using this method is more accurate than that using a fixed ratio between PM2.5 and AOD. Two versions of AOD from Terra (v4.0.1 and v5.2.6) are also compared in terms of the inversion methods and screening algorithms. The v5.2.6 AOD retrievals demonstrate better correlation with PM2.5 than v4.0.1 retrievals, but they have much less coverage because of the differences in the cloud-screening algorithm.

  17. Ultra-high resolution Fourier domain optical coherence tomography for resolving thin layers in painted works of art

    NASA Astrophysics Data System (ADS)

    Cheung, C. S.; Liang, Haida

    2013-05-01

    While OCT has been applied to the non-invasive examination of the stratigraphy of paint layers in recent years, it has been recognized that the resolutions of commercially available OCT cannot compete in depth resolution with conventional microscopic examination of cross-sections of paint samples. It is necessary to achieve resolutions better than 3 microns to resolve the thinnest layers of paint and varnish. In this paper, we demonstrate a Fourier domain ultrahigh resolution OCT at 810nm with depth resolution of 1.8 μm in air (or 1.2μm in varnish or paint).

  18. Modeling the Nucleus Laminaris of the Barn Owl: Achieving 20 ps Resolution on a 85-MHz-Clocked Digital Device

    PubMed Central

    Salomon, Ralf; Heinrich, Enrico; Joost, Ralf

    2012-01-01

    The nucleus laminaris of the barn owl auditory system is quite impressive, since its underlying time estimation is much better than the processing speed of the involved neurons. Since precise localization is also very important in many technical applications, this paper explores to what extent the main principles of the nucleus laminaris can be implemented in digital hardware. The first prototypical implementation yields a time resolution of about 20 ps, even though the chosen standard, low-cost device is clocked at only 85 MHz, which leads to an internal duty cycle of approximately 12 ns. In addition, this paper also explores the utility of an advanced sampling scheme, known as unfolding-in-time. It turns out that with this sampling method, the prototype can easily process input signals of up to 300 MHz, which is almost four times higher than the sampling rate. PMID:22347179

  19. Modeling the Nucleus Laminaris of the Barn Owl: Achieving 20 ps Resolution on a 85-MHz-Clocked Digital Device.

    PubMed

    Salomon, Ralf; Heinrich, Enrico; Joost, Ralf

    2012-01-01

    The nucleus laminaris of the barn owl auditory system is quite impressive, since its underlying time estimation is much better than the processing speed of the involved neurons. Since precise localization is also very important in many technical applications, this paper explores to what extent the main principles of the nucleus laminaris can be implemented in digital hardware. The first prototypical implementation yields a time resolution of about 20 ps, even though the chosen standard, low-cost device is clocked at only 85 MHz, which leads to an internal duty cycle of approximately 12 ns. In addition, this paper also explores the utility of an advanced sampling scheme, known as unfolding-in-time. It turns out that with this sampling method, the prototype can easily process input signals of up to 300 MHz, which is almost four times higher than the sampling rate. PMID:22347179

  20. Depth perception in autostereograms: 1/f noise is best.

    PubMed

    Yankelevsky, Yael; Shvartz, Ishai; Avraham, Tamar; Bruckstein, Alfred M

    2016-02-01

    An autostereogram is a single image that encodes depth information that pops out when looking at it. The trick is achieved by setting a basic 2D pattern and continuously replicating the local pattern at each point in the image with a shift defined by the desired disparity. In this work, we explore the dependency between the ease of perceiving depth in autostereograms and the choice of the basic pattern used for generating them. We report the results of three sets of psychophysical experiments using autostereograms generated from 2D random noise patterns having power spectra of the form 1/f(β) The experiments were designed to test the ability of human subjects to identify smooth low-resolution surfaces, as well as detail, in the form of higher-resolution objects in the depth profile, and to determine limits in identifying small objects as a function of their size. In accordance with the theory, we discover a significant advantage of the 1/f noise pattern (pink noise) for fast depth lock-in and fine detail detection, showing that such patterns are optimal choices for autostereogram design.

  1. Assessing resolution in super-resolution imaging.

    PubMed

    Demmerle, Justin; Wegel, Eva; Schermelleh, Lothar; Dobbie, Ian M

    2015-10-15

    Resolution is a central concept in all imaging fields, and particularly in optical microscopy, but it can be easily misinterpreted. The mathematical definition of optical resolution was codified by Abbe, and practically defined by the Rayleigh Criterion in the late 19th century. The limit of conventional resolution was also achieved in this period, and it was thought that fundamental constraints of physics prevented further increases in resolution. With the recent development of a range of super-resolution techniques, it is necessary to revisit the concept of optical resolution. Fundamental differences in super-resolution modalities mean that resolution is not a directly transferrable metric between techniques. This article considers the issues in resolution raised by these new technologies, and presents approaches for comparing resolution between different super-resolution methods.

  2. Achieving quasi-adiabatic thermal environment to maximize resolution power in very high-pressure liquid chromatography: Theory, models, and experiments.

    PubMed

    Gritti, Fabrice; Gilar, Martin; Jarrell, Joseph A

    2016-04-29

    A cylindrical vacuum chamber (inner diameter 5 cm) housing a narrow-bore 2.1 mm×100 mm column packed with 1.8 μm HSS-T3 fully porous particles was built in order to isolate thermally the chromatographic column from the external air environment. Consistent with statistical physics and the mean free path of air molecules, the experimental results show that natural air convection and conduction are fully eliminated for housing air pressures smaller than 10(-4) Torr. Heat radiation is minimized by wrapping up the column with low-emissivity aluminum-tape (emissivity coefficient ϵ=0.03 vs. 0.28 for polished stainless steel 316). Overall, the heat flux at the column wall is reduced by 96% with respect to standard still-air ovens. From a practical viewpoint, the efficiency of the column run at a flow rate of 0.6 mL/min at a constant 13,000 psi pressure drop (the viscous heat power is around 9 W/m) is improved by up to 35% irrespective of the analyte retention. Models of heat and mass transfer reveal that (1) the amplitude of the radial temperature gradient is significantly reduced from 0.30 to 0.01 K and (2) the observed improvement in resolution power stems from a more uniform distribution of the flow velocity across the column diameter. The eddy dispersion term in the van Deemter equation is reduced by 0.8±0.1 reduced plate height unit, a significant gain in column performance.

  3. Achieving quasi-adiabatic thermal environment to maximize resolution power in very high-pressure liquid chromatography: Theory, models, and experiments.

    PubMed

    Gritti, Fabrice; Gilar, Martin; Jarrell, Joseph A

    2016-04-29

    A cylindrical vacuum chamber (inner diameter 5 cm) housing a narrow-bore 2.1 mm×100 mm column packed with 1.8 μm HSS-T3 fully porous particles was built in order to isolate thermally the chromatographic column from the external air environment. Consistent with statistical physics and the mean free path of air molecules, the experimental results show that natural air convection and conduction are fully eliminated for housing air pressures smaller than 10(-4) Torr. Heat radiation is minimized by wrapping up the column with low-emissivity aluminum-tape (emissivity coefficient ϵ=0.03 vs. 0.28 for polished stainless steel 316). Overall, the heat flux at the column wall is reduced by 96% with respect to standard still-air ovens. From a practical viewpoint, the efficiency of the column run at a flow rate of 0.6 mL/min at a constant 13,000 psi pressure drop (the viscous heat power is around 9 W/m) is improved by up to 35% irrespective of the analyte retention. Models of heat and mass transfer reveal that (1) the amplitude of the radial temperature gradient is significantly reduced from 0.30 to 0.01 K and (2) the observed improvement in resolution power stems from a more uniform distribution of the flow velocity across the column diameter. The eddy dispersion term in the van Deemter equation is reduced by 0.8±0.1 reduced plate height unit, a significant gain in column performance. PMID:27040511

  4. On evaluation of depth accuracy in consumer depth sensors

    NASA Astrophysics Data System (ADS)

    Abd Aziz, Azim Zaliha; Wei, Hong; Ferryman, James

    2015-12-01

    This paper presents an experimental study of different depth sensors. The aim is to answer the question, whether these sensors give accurate data for general depth image analysis. The study examines the depth accuracy between three popularly used depth sensors; ASUS Xtion Prolive, Kinect Xbox 360 and Kinect for Windows v2. The main attention is to study on the stability of pixels in the depth image captured at several different sensor-object distances by measuring the depth returned by the sensors within specified time intervals. The experimental results show that the fluctuation (mm) of the random selected pixels within the target area, increases with increasing distance to the sensor, especially on the Kinect for Xbox 360 and the Asus Xtion Prolive. Both of these sensors provide pixels fluctuation between 20mm and 30mm at a sensor-object distance beyond 1500mm. However, the pixel's stability of the Kinect for Windows v2 not affected much with the distance between the sensor and the object. The maximum fluctuation for all the selected pixels of Kinect for Windows v2 is approximately 5mm at sensor-object distance of between 800mm and 3000mm. Therefore, in the optimal distance, the best stability achieved.

  5. Depth-resolved soft x-ray photoelectron emission microscopy in nanostructures via standing-wave excited photoemission

    SciTech Connect

    Kronast, F.; Ovsyannikov, R.; Kaiser, A.; Wiemann, C.; Yang, S.-H.; Locatelli, A.; Burgler, D.E.; Schreiber, R.; Salmassi, F.; Fischer, P.; Durr, H.A.; Schneider, C.M.; Eberhardt, W.; Fadley, C.S.

    2008-11-24

    We present an extension of conventional laterally resolved soft x-ray photoelectron emission microscopy. A depth resolution along the surface normal down to a few {angstrom} can be achieved by setting up standing x-ray wave fields in a multilayer substrate. The sample is an Ag/Co/Au trilayer, whose first layer has a wedge profile, grown on a Si/MoSi2 multilayer mirror. Tuning the incident x-ray to the mirror Bragg angle we set up standing x-ray wave fields. We demonstrate the resulting depth resolution by imaging the standing wave fields as they move through the trilayer wedge structure.

  6. A depth-of-interaction PET detector using mutual gain-equalized silicon photomultiplier

    SciTech Connect

    W. Xi, A.G, Weisenberger, H. Dong, Brian Kross, S. Lee, J. McKisson, Carl Zorn

    2012-02-01

    We developed a prototype high resolution, high efficiency depth-encoding detector for PET applications based on dual-ended readout of LYSO array with two silicon photomultipliers (SiPMs). Flood images, energy resolution, and depth-of-interaction (DOI) resolution were measured for a LYSO array - 0.7 mm in crystal pitch and 10 mm in thickness - with four unpolished parallel sides. Flood images were obtained such that individual crystal element in the array is resolved. The energy resolution of the entire array was measured to be 33%, while individual crystal pixel elements utilizing the signal from both sides ranged from 23.3% to 27%. By applying a mutual-gain equalization method, a DOI resolution of 2 mm for the crystal array was obtained in the experiments while simulations indicate {approx}1 mm DOI resolution could possibly be achieved. The experimental DOI resolution can be further improved by obtaining revised detector supporting electronics with better energy resolutions. This study provides a detailed detector calibration and DOI response characterization of the dual-ended readout SiPM-based PET detectors, which will be important in the design and calibration of a PET scanner in the future.

  7. Depth Perception In Remote Stereoscopic Viewing Systems

    NASA Technical Reports Server (NTRS)

    Diner, Daniel B.; Von Sydow, Marika

    1989-01-01

    Report describes theoretical and experimental studies of perception of depth by human operators through stereoscopic video systems. Purpose of such studies to optimize dual-camera configurations used to view workspaces of remote manipulators at distances of 1 to 3 m from cameras. According to analysis, static stereoscopic depth distortion decreased, without decreasing stereoscopitc depth resolution, by increasing camera-to-object and intercamera distances and camera focal length. Further predicts dynamic stereoscopic depth distortion reduced by rotating cameras around center of circle passing through point of convergence of viewing axes and first nodal points of two camera lenses.

  8. Conflicts and Communication between High-Achieving Chinese American Adolescents and Their Parents

    ERIC Educational Resources Information Center

    Qin, Desiree Baolian; Chang, Tzu-Fen; Han, Eun-Jin; Chee, Grace

    2012-01-01

    Drawing on in-depth interview data collected on 18 high-achieving Chinese American students, the authors examine domains of acculturation-based conflicts, parent and child internal conflicts, and conflict resolution in their families. Their analyses show that well-established negative communication patterns in educational expectations, divergent…

  9. Confocal Raman microspectroscopy on excised human skin: uncertainties in depth profiling and mathematical correction applied to dermatological drug permeation.

    PubMed

    Tfayli, A; Piot, O; Manfait, M

    2008-05-01

    Confocal Raman microspectroscopy represents the advantage of giving structural and conformational information on samples without any destructive treatment. Recently, several studies were achieved to study the skin hydration, endogenous and exogenous molecules repartition in the skin using the confocal feature of this technique. Meanwhile, when working through a material boundary with a different refractive index, the main limitation remains the spatial precision, especially the distortion in the depth and the depth resolution. Recently, several authors described mathematical models to correct the depth and the resolution values. In this study, we combined theoretical approaches, proposed by different authors with experimental measurements to try to find out the most appropriate approach for correction. We then applied the corrections on in-depth profiles tracking the penetration of Metronidazole, a drug produced by Galderma for rosacea treatment, through excised human skin. PMID:19343645

  10. Confocal Raman microspectroscopy on excised human skin: uncertainties in depth profiling and mathematical correction applied to dermatological drug permeation.

    PubMed

    Tfayli, A; Piot, O; Manfait, M

    2008-05-01

    Confocal Raman microspectroscopy represents the advantage of giving structural and conformational information on samples without any destructive treatment. Recently, several studies were achieved to study the skin hydration, endogenous and exogenous molecules repartition in the skin using the confocal feature of this technique. Meanwhile, when working through a material boundary with a different refractive index, the main limitation remains the spatial precision, especially the distortion in the depth and the depth resolution. Recently, several authors described mathematical models to correct the depth and the resolution values. In this study, we combined theoretical approaches, proposed by different authors with experimental measurements to try to find out the most appropriate approach for correction. We then applied the corrections on in-depth profiles tracking the penetration of Metronidazole, a drug produced by Galderma for rosacea treatment, through excised human skin.

  11. Photon counting compressive depth mapping.

    PubMed

    Howland, Gregory A; Lum, Daniel J; Ware, Matthew R; Howell, John C

    2013-10-01

    We demonstrate a compressed sensing, photon counting lidar system based on the single-pixel camera. Our technique recovers both depth and intensity maps from a single under-sampled set of incoherent, linear projections of a scene of interest at ultra-low light levels around 0.5 picowatts. Only two-dimensional reconstructions are required to image a three-dimensional scene. We demonstrate intensity imaging and depth mapping at 256 × 256 pixel transverse resolution with acquisition times as short as 3 seconds. We also show novelty filtering, reconstructing only the difference between two instances of a scene. Finally, we acquire 32 × 32 pixel real-time video for three-dimensional object tracking at 14 frames-per-second. PMID:24104293

  12. Remote sensing of stream depths with hydraulically assisted bathymetry (HAB) models

    NASA Astrophysics Data System (ADS)

    Fonstad, Mark A.; Marcus, W. Andrew

    2005-12-01

    This article introduces a technique for using a combination of remote sensing imagery and open-channel flow principles to estimate depths for each pixel in an imaged river. This technique, which we term hydraulically assisted bathymetry (HAB), uses a combination of local stream gage information on discharge, image brightness data, and Manning-based estimates of stream resistance to calculate water depth. The HAB technique does not require ground-truth depth information at the time of flight. HAB can be accomplished with multispectral or hyperspectral data, and therefore can be applied over entire watersheds using standard high spatial resolution satellite or aerial images. HAB also has the potential to be applied retroactively to historic imagery, allowing researchers to map temporal changes in depth. We present two versions of the technique, HAB-1 and HAB-2. HAB-1 is based primarily on the geometry, discharge and velocity relationships of river channels. Manning's equation (assuming average depth approximates the hydraulic radius), the discharge equation, and the assumption that the frequency distribution of depths within a cross-section approximates that of a triangle are combined with discharge data from a local station, width measurements from imagery, and slope measurements from maps to estimate minimum, average and maximum depths at a multiple cross-sections. These depths are assigned to pixels of maximum, average, and minimum brightness within the cross-sections to develop a brightness-depth relation to estimate depths throughout the remainder of the river. HAB-2 is similar to HAB-1 in operation, but the assumption that the distribution of depths approximates that of a triangle is replaced by an optical Beer-Lambert law of light absorbance. In this case, the flow equations and the optical equations are used to iteratively scale the river pixel values until their depths produce a discharge that matches that of a nearby gage. R2 values for measured depths

  13. Resolution limits of ultrafast ultrasound localization microscopy.

    PubMed

    Desailly, Yann; Pierre, Juliette; Couture, Olivier; Tanter, Mickael

    2015-11-21

    As in other imaging methods based on waves, the resolution of ultrasound imaging is limited by the wavelength. However, the diffraction-limit can be overcome by super-localizing single events from isolated sources. In recent years, we developed plane-wave ultrasound allowing frame rates up to 20,000 fps. Ultrafast processes such as rapid movement or disruption of ultrasound contrast agents (UCA) can thus be monitored, providing us with distinct punctual sources that could be localized beyond the diffraction limit. We previously showed experimentally that resolutions beyond λ/10 can be reached in ultrafast ultrasound localization microscopy (uULM) using a 128 transducer matrix in reception. Higher resolutions are theoretically achievable and the aim of this study is to predict the maximum resolution in uULM with respect to acquisition parameters (frequency, transducer geometry, sampling electronics). The accuracy of uULM is the error on the localization of a bubble, considered a point-source in a homogeneous medium. The proposed model consists in two steps: determining the timing accuracy of the microbubble echo in radiofrequency data, then transferring this time accuracy into spatial accuracy. The simplified model predicts a maximum resolution of 40 μm for a 1.75 MHz transducer matrix composed of two rows of 64 elements. Experimental confirmation of the model was performed by flowing microbubbles within a 60 μm microfluidic channel and localizing their blinking under ultrafast imaging (500 Hz frame rate). The experimental resolution, determined as the standard deviation in the positioning of the microbubbles, was predicted within 6 μm (13%) of the theoretical values and followed the analytical relationship with respect to the number of elements and depth. Understanding the underlying physical principles determining the resolution of superlocalization will allow the optimization of the imaging setup for each organ. Ultimately, accuracies better than the size of

  14. Resolution limits of ultrafast ultrasound localization microscopy.

    PubMed

    Desailly, Yann; Pierre, Juliette; Couture, Olivier; Tanter, Mickael

    2015-11-21

    As in other imaging methods based on waves, the resolution of ultrasound imaging is limited by the wavelength. However, the diffraction-limit can be overcome by super-localizing single events from isolated sources. In recent years, we developed plane-wave ultrasound allowing frame rates up to 20,000 fps. Ultrafast processes such as rapid movement or disruption of ultrasound contrast agents (UCA) can thus be monitored, providing us with distinct punctual sources that could be localized beyond the diffraction limit. We previously showed experimentally that resolutions beyond λ/10 can be reached in ultrafast ultrasound localization microscopy (uULM) using a 128 transducer matrix in reception. Higher resolutions are theoretically achievable and the aim of this study is to predict the maximum resolution in uULM with respect to acquisition parameters (frequency, transducer geometry, sampling electronics). The accuracy of uULM is the error on the localization of a bubble, considered a point-source in a homogeneous medium. The proposed model consists in two steps: determining the timing accuracy of the microbubble echo in radiofrequency data, then transferring this time accuracy into spatial accuracy. The simplified model predicts a maximum resolution of 40 μm for a 1.75 MHz transducer matrix composed of two rows of 64 elements. Experimental confirmation of the model was performed by flowing microbubbles within a 60 μm microfluidic channel and localizing their blinking under ultrafast imaging (500 Hz frame rate). The experimental resolution, determined as the standard deviation in the positioning of the microbubbles, was predicted within 6 μm (13%) of the theoretical values and followed the analytical relationship with respect to the number of elements and depth. Understanding the underlying physical principles determining the resolution of superlocalization will allow the optimization of the imaging setup for each organ. Ultimately, accuracies better than the size of

  15. Molecular depth profiling by wedged crater beveling.

    PubMed

    Mao, Dan; Lu, Caiyan; Winograd, Nicholas; Wucher, Andreas

    2011-08-15

    Time-of-flight secondary ion mass spectrometry and atomic force microscopy are employed to characterize a wedge-shaped crater eroded by a 40-keV C(60)(+) cluster ion beam on an organic film of Irganox 1010 doped with Irganox 3114 delta layers. From an examination of the resulting surface, the information about depth resolution, topography, and erosion rate can be obtained as a function of crater depth for every depth in a single experiment. It is shown that when measurements are performed at liquid nitrogen temperature, a constant erosion rate and reduced bombardment induced surface roughness is observed. At room temperature, however, the erosion rate drops by ∼(1)/(3) during the removal of the 400 nm Irganox film and the roughness gradually increased to from 1 nm to ∼4 nm. From SIMS lateral images of the beveled crater and AFM topography results, depth resolution was further improved by employing glancing angles of incidence and lower primary ion beam energy. Sub-10 nm depth resolution was observed under the optimized conditions on a routine basis. In general, we show that the wedge-crater beveling is an important tool for elucidating the factors that are important for molecular depth profiling experiments.

  16. Learning the missing values in depth maps

    NASA Astrophysics Data System (ADS)

    Yin, Xuanwu; Wang, Guijin; Zhang, Chun; Liao, Qingmin

    2013-12-01

    In this paper, we consider the task of hole filling in depth maps, with the help of an associated color image. We take a supervised learning approach to solve this problem. The model is learnt from the training set, which contain pixels that have depth values. Then we apply supervised learning to predict the depth values in the holes. Our model uses a regional Markov Random Field (MRF) that incorporates multiscale absolute and relative features (computed from the color image), and models depths not only at individual points but also between adjacent points. The experiments show that the proposed approach is able to recover fairly accurate depth values and achieve a high quality depth map.

  17. Resolution of sleepiness and fatigue: a comparison of bupropion and selective serotonin reuptake inhibitors in subjects with major depressive disorder achieving remission at doses approved in the European Union.

    PubMed

    Cooper, James A; Tucker, Vivian L; Papakostas, George I

    2014-02-01

    Unlike selective serotonin reuptake inhibitors (SSRIs), bupropion may be classified as a dual noradrenaline and dopamine reuptake inhibitor, a difference with potential implications for the treatment of residual sleepiness and fatigue in major depressive disorder (MDD). Post-hoc analysis of subjects with remitted MDD was performed on data pooled from six double-blind, randomized trials comparing the European Union (EU)-approved dose of ≤300 mg/day bupropion with SSRIs (sertraline, paroxetine or escitalopram) for the resolution of sleepiness and fatigue. Hypersomnia score was defined as the sum of scores of the Hamilton Depression Rating Scale (HDRS) items 22, 23, and 24; fatigue score as HDRS item 13 score; and remission as HDRS-17≤7. Similar proportions of bupropion- and SSRI-treated subjects achieved remission at study endpoint (169/343, 49.3% vs 324/656, 49.4%; last observation carried forward (LOCF), p=0.45). Fewer bupropion-treated remitters had residual symptoms of sleepiness (32/169, 18.9% vs 104/324, 32.1%; p<0.01) and fatigue (33/169, 19.5% vs 98/324, 30.2%; p<0.05). Bupropion-treated remitters also showed greater improvement (mean change from baseline) in sleepiness (p<0.05) and fatigue scores (p<0.01) at endpoint: benefits were evident from week 2 for sleepiness (p<0.01) and week 4 for fatigue (p<0.01). Bupropion treatment at the EU-approved dose of ≤300 mg/day may offer advantages over SSRIs in the resolution of sleepiness and fatigue in remitted MDD patients.

  18. Stereoscopic depth constancy

    PubMed Central

    Guan, Phillip

    2016-01-01

    Depth constancy is the ability to perceive a fixed depth interval in the world as constant despite changes in viewing distance and the spatial scale of depth variation. It is well known that the spatial frequency of depth variation has a large effect on threshold. In the first experiment, we determined that the visual system compensates for this differential sensitivity when the change in disparity is suprathreshold, thereby attaining constancy similar to contrast constancy in the luminance domain. In a second experiment, we examined the ability to perceive constant depth when the spatial frequency and viewing distance both changed. To attain constancy in this situation, the visual system has to estimate distance. We investigated this ability when vergence, accommodation and vertical disparity are all presented accurately and therefore provided veridical information about viewing distance. We found that constancy is nearly complete across changes in viewing distance. Depth constancy is most complete when the scale of the depth relief is constant in the world rather than when it is constant in angular units at the retina. These results bear on the efficacy of algorithms for creating stereo content. This article is part of the themed issue ‘Vision in our three-dimensional world’. PMID:27269596

  19. Stereoscopic depth constancy.

    PubMed

    Guan, Phillip; Banks, Martin S

    2016-06-19

    Depth constancy is the ability to perceive a fixed depth interval in the world as constant despite changes in viewing distance and the spatial scale of depth variation. It is well known that the spatial frequency of depth variation has a large effect on threshold. In the first experiment, we determined that the visual system compensates for this differential sensitivity when the change in disparity is suprathreshold, thereby attaining constancy similar to contrast constancy in the luminance domain. In a second experiment, we examined the ability to perceive constant depth when the spatial frequency and viewing distance both changed. To attain constancy in this situation, the visual system has to estimate distance. We investigated this ability when vergence, accommodation and vertical disparity are all presented accurately and therefore provided veridical information about viewing distance. We found that constancy is nearly complete across changes in viewing distance. Depth constancy is most complete when the scale of the depth relief is constant in the world rather than when it is constant in angular units at the retina. These results bear on the efficacy of algorithms for creating stereo content.This article is part of the themed issue 'Vision in our three-dimensional world'.

  20. Self-interference fluorescence microscopy: three dimensional fluorescence imaging without depth scanning

    PubMed Central

    de Groot, Mattijs; Evans, Conor L.; de Boer, Johannes F.

    2012-01-01

    We present a new method for high-resolution, three-dimensional fluorescence imaging. In contrast to beam-scanning confocal microscopy, where the laser focus must be scanned both laterally and axially to collect a volume, we obtain depth information without the necessity of depth scanning. In this method, the emitted fluorescence is collected in the backward direction and is sent through a phase plate that encodes the depth information into the phase of a spectrally resolved interference pattern. We demonstrate that decoding this phase information allows for depth localization accuracy better than 4 µm over a 500 µm depth-of-field. In a high numerical aperture configuration with a much smaller depth of field, a localization accuracy of tens of nanometers can be achieved. This approach is ideally suited for miniature endoscopes, where space limitations at the endoscope tip render depth scanning difficult. We illustrate the potential for 3D visualization of complex biological samples by constructing a three-dimensional volume of the microvasculature of ex vivo murine heart tissue from a single 2D scan. PMID:22772223

  1. Motivation with Depth.

    ERIC Educational Resources Information Center

    DiSpezio, Michael A.

    2000-01-01

    Presents an illusional arena by offering experience in optical illusions in which students must apply critical analysis to their innate information gathering systems. Introduces different types of depth illusions for students to experience. (ASK)

  2. Depth Optimization Study

    DOE Data Explorer

    Kawase, Mitsuhiro

    2009-11-22

    The zipped file contains a directory of data and routines used in the NNMREC turbine depth optimization study (Kawase et al., 2011), and calculation results thereof. For further info, please contact Mitsuhiro Kawase at kawase@uw.edu. Reference: Mitsuhiro Kawase, Patricia Beba, and Brian Fabien (2011), Finding an Optimal Placement Depth for a Tidal In-Stream Conversion Device in an Energetic, Baroclinic Tidal Channel, NNMREC Technical Report.

  3. Cell depth imaging by point laser scanning fluorescence microscopy with an optical disk pickup head

    NASA Astrophysics Data System (ADS)

    Tsai, Rung-Ywan; Chen, Jung-Po; Lee, Yuan-Chin; Chiang, Hung-Chih; Cheng, Chih-Ming; Huang, Chun-Chieh; Huang, Tai-Ting; Cheng, Chung-Ta; Tiao, Golden

    2015-09-01

    A compact, cost-effective, and position-addressable digital laser scanning microscopy (DLSM) instrument is made using a commercially available Blu-ray disc read-only memory (BD-ROM) pickup head. Fluorescent cell images captured by DLSM have resolutions of 0.38 µm. Because of the position-addressable function, multispectral fluorescence cell images are captured using the same sample slide with different excitation laser sources. Specially designed objective lenses with the same working distance as the image-capturing beam are used for the different excitation laser sources. By accurately controlling the tilting angles of the sample slide or by moving the collimator lens of the image-capturing beam, the fluorescence cell images along different depth positions of the sample are obtained. Thus, z-section images with micrometer-depth resolutions are achievable.

  4. Underwater depth imaging using time-correlated single photon counting

    NASA Astrophysics Data System (ADS)

    Maccarone, Aurora; McCarthy, Aongus; Ren, Ximing; Warburton, Ryan E.; Wallace, Andy M.; Moffat, James; Petillot, Yvan; Buller, Gerald S.

    2015-05-01

    We investigate the potential of a depth imaging system for underwater environments. This system is based on the timeof- flight approach and the time correlated single-photon counting (TCSPC) technique. We report laboratory-based measurements and explore the potential of achieving sub-centimeter xyz resolution at 10's meters stand-off distances. Initial laboratory-based experiments demonstrate depth imaging performed over distances of up to 1.8 meters and under a variety of scattering conditions. The system comprised a monostatic transceiver unit, a fiber-coupled supercontinuum laser with a wavelength tunable acousto-optic filter, and a fiber-coupled individual silicon single-photon avalanche diode (SPAD). The scanning in xy was performed using a pair of galvonometer mirrors directing both illumination and scattered returns via a coaxial optical configuration. Target objects were placed in a 110 liter capacity tank and depth images were acquired through approximately 1.7 meters of water containing different concentrations of scattering agent. Depth images were acquired in clear and highly scattering water using per-pixel acquisition times in the range 0.5-100 ms at average optical powers in the range 0.8 nW to 120 μW. Based on the laboratory measurements, estimations of potential performance, including maximum range possible, were performed with a model based on the LIDAR equation. These predictions will be presented for different levels of scattering agent concentration, optical powers, wavelengths and comparisons made with naturally occurring environments. The experimental and theoretical results indicate that the TCSPC technique has potential for highresolution underwater depth profile measurements.

  5. Depth Sensing for Improved Control of Lower Limb Prostheses.

    PubMed

    Krausz, Nili Eliana; Lenzi, Tommaso; Hargrove, Levi J

    2015-11-01

    Powered lower limb prostheses have potential to improve the quality of life of individuals with amputations by enabling all daily activities. However, seamless ambulation mode recognition is necessary to achieve this goal and is not yet a clinical reality. Current intent recognition systems use mechanical and EMG sensors to estimate prosthesis and user status. We propose to complement these systems by integrating information about the environment obtained through the depth sensing. This paper presents the design, characterization, and the early validation of a novel stair segmentation system based on Microsoft Kinect. Static and dynamic tests were performed. A first experiment showed how the resolution of the depth camera affects the speed and the accuracy of segmentation. A second test proved the robustness of the algorithm to different staircases. Finally, we performed an online walking test with the stair segmentation and related measures recorded online at >5 frames/s. Experimental results show that the proposed algorithm allows for an accurate estimate of distance, angle of intersection, number of steps, stair height, and stair depth for a set of stairs in the environment. The online test produced an estimate of whether the individual was approaching stairs in real time with approximately 98.8% accuracy.

  6. Mesoscale oceanic response to wind events off central California in spring 1989: CTD surveys and AVHRR imagery. [Conductivity/temperature/depth surveys; Selected Advanced Very High Resolution Radiometer satellite imaging

    SciTech Connect

    Schwing, F.B.; Husby, D.M. ); Garfield, N.; Tracy, D.E. )

    1991-11-01

    Analysis of hydrographic data obtained during juvenile groundfish surveys, in relation to local wind forcing and AVHRR sea-surface temperature imagery, reveals that the oceanic region off central California between Point Reyes and Point Sur in spring 1989 was characterized by complex circulation patterns and considerable temporal and mesoscale variability. The 'spring transition' to upwelling-favorable winds is most clearly evidenced by rapid, large decreases in SST (up to 4-5C) measured at four meteorological buoys. Daily-averaged winds are spatially coherent and oscillate between upwelling-favorable and relaxation conditions at 3-10-day intervals. Persistent upwelling centers near Point Reyes and Point Ano Nuevo were characterized by relatively cool, salty (8-10C, 33.6-34.0 psu) water in the upper 50 m, which is derived from offshore water at depths of 50-100 m. Water-mass analysis reveals that upwelled water is advected equatorward from its source. Some upwelled water is transported into shallow coastal areas and warmed. Alongshelf fronts between relatively warm, low-salinity ([gt]13C, [lt]33.5 psu) offshore water and cool, higher-salinity upwelled water are advected onshore in response to wind relaxation or reversal events: frontal gradients intensify at these times. AVHRR imagery verifies the spatial patterns and complex mesoscale variability of the near-surface patterns observed in the CTD survey data. Eddylike hydrographic features are noted with horizontal scales on the order of the station spacing (10 km). How the complex circulation patterns and intense mesoscale spatial and temporal variability affect the survival and subsequent recruitment of juvenile groundfish is discussed.

  7. Jupiter Clouds in Depth

    NASA Technical Reports Server (NTRS)

    2000-01-01

    [figure removed for brevity, see original site] 619 nm [figure removed for brevity, see original site] 727 nm [figure removed for brevity, see original site] 890 nm

    Images from NASA's Cassini spacecraft using three different filters reveal cloud structures and movements at different depths in the atmosphere around Jupiter's south pole.

    Cassini's cameras come equipped with filters that sample three wavelengths where methane gas absorbs light. These are in the red at 619 nanometer (nm) wavelength and in the near-infrared at 727 nm and 890 nm. Absorption in the 619 nm filter is weak. It is stronger in the 727 nm band and very strong in the 890 nm band where 90 percent of the light is absorbed by methane gas. Light in the weakest band can penetrate the deepest into Jupiter's atmosphere. It is sensitive to the amount of cloud and haze down to the pressure of the water cloud, which lies at a depth where pressure is about 6 times the atmospheric pressure at sea level on the Earth). Light in the strongest methane band is absorbed at high altitude and is sensitive only to the ammonia cloud level and higher (pressures less than about one-half of Earth's atmospheric pressure) and the middle methane band is sensitive to the ammonia and ammonium hydrosulfide cloud layers as deep as two times Earth's atmospheric pressure.

    The images shown here demonstrate the power of these filters in studies of cloud stratigraphy. The images cover latitudes from about 15 degrees north at the top down to the southern polar region at the bottom. The left and middle images are ratios, the image in the methane filter divided by the image at a nearby wavelength outside the methane band. Using ratios emphasizes where contrast is due to methane absorption and not to other factors, such as the absorptive properties of the cloud particles, which influence contrast at all wavelengths.

    The most prominent feature seen in all three filters is the polar stratospheric haze that makes Jupiter

  8. High-resolution optoacoustic mesoscopy with a 24 MHz multidetector translate-rotate scanner.

    PubMed

    Gateau, Jérôme; Chekkoury, Andrei; Ntziachristos, Vasilis

    2013-10-01

    Optoacoustic (photoacoustic) mesoscopy aims at high-resolution optical imaging of anatomical, functional, and cellular parameters at depths that go well beyond those of optical-resolution optical or optoacoustic microscopy i.e., reaching several millimeters in depth. The approach utilizes tomography to achieve ultrasonic-diffraction resolution and operates at high-ultrasound frequencies (20 to 200 MHz) induced by few-nanosecond laser pulse excitation of tissues. We investigated here the performance of optoacoustic mesoscopy implemented at 24 MHz center frequency and its ability to resolve optical absorption contrast in the mouse kidney ex vivo. The developed system achieved better than 30 μm in-plane resolution and 110 μm elevation resolution over a cylindrical volume of 9-mm diameter and 9-mm height. This unprecedented combination of resolution and depth was achieved by implementing a translate-rotate detection geometry and by tomographic reconstruction. The approach yielded images of optically absorbing structures with a level of detail never-before visualized in an intact mouse kidney and allows insights into their unperturbed architecture. We discuss the ability to offer multispectral acquisitions and enable in vivo imaging.

  9. Lunar Far Side Regolith Depth

    NASA Astrophysics Data System (ADS)

    Bart, G. D.; Melosh, H. J.

    2005-08-01

    The lunar far side contains the South Pole Aitken Basin, which is the largest known impact basin in the solar system, and is enhanced in titanium and iron compared to the rest of the lunar highlands. Although we have known of this enigmatic basin since the 60's, most lunar photography and science covered the equatorial near side where the Apollo spacecraft landed. With NASA's renewed interest in the Moon, the South Pole Aitken Basin is a likely target for future exploration. The regolith depth is a crucial measurement for understanding the source of the surface material in the Basin. On the southern far side of the Moon (20 S, 180 W), near the north edge of the Basin, we determined the regolith depth by examining 11 flat-floored craters about 200 m in diameter. We measured the ratio of the diameter of the flat floor to the diameter of the crater, and used it to calculate the regolith thickness using the method of Quaide and Oberbeck (1968). We used Apollo 15 panoramic images --- still the highest resolution images available for this region of the Moon. We found the regolith depth at that location to be about 40 m. This value is significantly greater than values for the lunar near side: 3 m (Oceanus Procellarum), 16 m (Hipparchus), and 1-10 m at the Surveyor landing sites. The thicker value obtained for the far side regolith is consistent with the older age of the far side. It also suggests that samples returned from the far side may have originated from deeper beneath the surface than their near side counterparts.

  10. Layered compression for high-precision depth data.

    PubMed

    Miao, Dan; Fu, Jingjing; Lu, Yan; Li, Shipeng; Chen, Chang Wen

    2015-12-01

    With the development of depth data acquisition technologies, access to high-precision depth with more than 8-b depths has become much easier and determining how to efficiently represent and compress high-precision depth is essential for practical depth storage and transmission systems. In this paper, we propose a layered high-precision depth compression framework based on an 8-b image/video encoder to achieve efficient compression with low complexity. Within this framework, considering the characteristics of the high-precision depth, a depth map is partitioned into two layers: 1) the most significant bits (MSBs) layer and 2) the least significant bits (LSBs) layer. The MSBs layer provides rough depth value distribution, while the LSBs layer records the details of the depth value variation. For the MSBs layer, an error-controllable pixel domain encoding scheme is proposed to exploit the data correlation of the general depth information with sharp edges and to guarantee the data format of LSBs layer is 8 b after taking the quantization error from MSBs layer. For the LSBs layer, standard 8-b image/video codec is leveraged to perform the compression. The experimental results demonstrate that the proposed coding scheme can achieve real-time depth compression with satisfactory reconstruction quality. Moreover, the compressed depth data generated from this scheme can achieve better performance in view synthesis and gesture recognition applications compared with the conventional coding schemes because of the error control algorithm. PMID:26415171

  11. A Conflict Resolution Model

    ERIC Educational Resources Information Center

    Davidson, John; Wood, Christine

    2004-01-01

    The Conflict Resolution Model was formulated by a group of Australian psychologists who set about integrating the literature on achieving mutually beneficial outcomes in a conflict situation in order to create a best-practice prescriptive process for conflict resolution. A number of experimental studies conducted at the University of Tasmania with…

  12. Quantification of AES depth profiles by the MRI model

    NASA Astrophysics Data System (ADS)

    Kovač, Janez; Zalar, Anton; Praček, Borut

    2003-02-01

    The main physical effects that contribute to interface broadening in the sputter depth profiles of polycrystalline metallic multilayer structures were studied by comparison of measured and simulated AES depth profiles. An algorithm based on the so-called mixing-roughness-information depth (MRI) model was used to simulate AES depth profiles of Ni/Cr multilayer structures with different roughnesses of the initial surfaces. The simulated depth profiles were compared with measurements performed at two different depth profiling parameters on the Ni/Cr and Al/Ni/Cr multilayer structures with an initial surface roughness of about 1.0 and 21.5 nm, respectively. The comparison of simulated and measured depth profiles enabled us to separate and estimate different contributions to the interface broadening, as well as their dependence on the sputter depth. We found that roughness was the dominant factor related to depth resolution with respect to the information depth and atomic mixing contribution. The values of roughness introduced into the simulation algorithm coincided well with the values measured by AFM at the initial surface and after depth profiling. The results showed the capability of the simulation procedure based on the MRI model to separate and evaluate different contributions to the depth resolution.

  13. Depth profiling of gold nanoparticles and characterization of point spread functions in reconstructed and human skin using multiphoton microscopy.

    PubMed

    Labouta, Hagar I; Hampel, Martina; Thude, Sibylle; Reutlinger, Katharina; Kostka, Karl-Heinz; Schneider, Marc

    2012-01-01

    Multiphoton microscopy has become popular in studying dermal nanoparticle penetration. This necessitates studying the imaging parameters of multiphoton microscopy in skin as an imaging medium, in terms of achievable detection depths and the resolution limit. This would simulate real-case scenarios rather than depending on theoretical values determined under ideal conditions. This study has focused on depth profiling of sub-resolution gold nanoparticles (AuNP) in reconstructed (fixed and unfixed) and human skin using multiphoton microscopy. Point spread functions (PSF) were determined for the used water-immersion objective of 63×/NA = 1.2. Factors such as skin-tissue compactness and the presence of wrinkles were found to deteriorate the accuracy of depth profiling. A broad range of AuNP detectable depths (20-100 μm) in reconstructed skin was observed. AuNP could only be detected up to ∼14 μm depth in human skin. Lateral (0.5 ± 0.1 μm) and axial (1.0 ± 0.3 μm) PSF in reconstructed and human specimens were determined. Skin cells and intercellular components didn't degrade the PSF with depth. In summary, the imaging parameters of multiphoton microscopy in skin and practical limitations encountered in tracking nanoparticle penetration using this approach were investigated.

  14. High-resolution light field reconstruction using a hybrid imaging system.

    PubMed

    Wang, Xiang; Li, Lin; Hou, GuangQi

    2016-04-01

    Recently, light field cameras have drawn much attraction for their innovative performance in photographic and scientific applications. However, narrow baselines and constrained spatial resolution of current light field cameras impose restrictions on their usability. Therefore, we design a hybrid imaging system containing a light field camera and a high-resolution digital single lens reflex camera, and these two kinds of cameras share the same optical path with a beam splitter so as to achieve the reconstruction of high-resolution light fields. The high-resolution 4D light fields are reconstructed with a phase-based perspective variation strategy. First, we apply complex steerable pyramid decomposition on the high-resolution image from the digital single lens reflex camera. Then, we perform phase-based perspective-shift processing with the disparity value, which is extracted from the upsampled light field depth map, to create high-resolution synthetic light field images. High-resolution digital refocused images and high-resolution depth maps can be generated in this way. Furthermore, controlling the magnitude of the perspective shift enables us to change the depth of field rendering in the digital refocused images. We show several experimental results to demonstrate the effectiveness of our approach.

  15. In vivo deconvolution acoustic-resolution photoacoustic microscopy in three dimensions.

    PubMed

    Cai, De; Li, Zhongfei; Chen, Sung-Liang

    2016-02-01

    Acoustic-resolution photoacoustic microscopy (ARPAM) provides a spatial resolution on the order of tens of micrometers, and is becoming an essential tool for imaging fine structures, such as the subcutaneous microvasculature. High lateral resolution of ARPAM is achieved using high numerical aperture (NA) of acoustic transducer; however, the depth of focus and working distance will be deteriorated correspondingly, thus sacrificing the imaging range and accessible depth. The axial resolution of ARPAM is limited by the transducer's bandwidth. In this work, we develop deconvolution ARPAM (D-ARPAM) in three dimensions that can improve the lateral resolution by 1.8 and 3.7 times and the axial resolution by 1.7 and 2.7 times, depending on the adopted criteria, using a 20-MHz focused transducer without physically increasing its NA and bandwidth. The resolution enhancement in three dimensions by D-ARPAM is also demonstrated by in vivo imaging of the microvasculature of a chick embryo. The proposed D-ARPAM has potential for biomedical imaging that simultaneously requires high spatial resolution, extended imaging range, and long accessible depth.

  16. Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging

    NASA Astrophysics Data System (ADS)

    Zhu, Dexi; Shen, Meixiao; Jiang, Hong; Li, Ming; Wang, Michael R.; Wang, Yuhong; Ge, Lili; Qu, Jia; Wang, Jianhua

    2011-12-01

    Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.

  17. Burn Depth Monitor

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Supra Medical Systems is successfully marketing a device that detects the depth of burn wounds in human skin. To develop the product, the companyused technology developed by NASA Langley physicists looking for better ultrasonic detection of small air bubbles and cracks in metal. The device is being marketed to burn wound analysis and treatment centers. Through a Space Act agreement, NASA and the company are also working to further develop ultrasonic instruments for new medical applications.

  18. Burn Depth Monitor

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Supra Medical Systems is successfully marketing a device that detects the depth of burn wounds in human skin. To develop the product, the company used technology developed by NASA Langley physicists looking for better ultrasonic detection of small air bubbles and cracks in metal. The device is being marketed to burn wound analysis and treatment centers. Through a Space Act agreement, NASA and the company are also working to further develop ultrasonic instruments for new medical applications

  19. Burn Depth Monitor

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Supra Medical Systems is successfully marketing a device that detects the depth of burn wounds in human skin. To develop the product, the company used technology developed by NASA Langley physicists looking for better ultrasonic detection of small air bubbles and cracks in metal. The device is being marketed to burn wound analysis and treatment centers. Through a Space Act agreement, NASA and the company are also working to further develop ultrasonic instruments for new medical applications.

  20. Variable depth core sampler

    DOEpatents

    Bourgeois, P.M.; Reger, R.J.

    1996-02-20

    A variable depth core sampler apparatus is described comprising a first circular hole saw member, having longitudinal sections that collapses to form a point and capture a sample, and a second circular hole saw member residing inside said first hole saw member to support the longitudinal sections of said first hole saw member and prevent them from collapsing to form a point. The second hole saw member may be raised and lowered inside said first hole saw member. 7 figs.

  1. Variable depth core sampler

    DOEpatents

    Bourgeois, Peter M.; Reger, Robert J.

    1996-01-01

    A variable depth core sampler apparatus comprising a first circular hole saw member, having longitudinal sections that collapses to form a point and capture a sample, and a second circular hole saw member residing inside said first hole saw member to support the longitudinal sections of said first hole saw member and prevent them from collapsing to form a point. The second hole saw member may be raised and lowered inside said first hole saw member.

  2. Seismic depth conversion vs. structural validation

    NASA Astrophysics Data System (ADS)

    Totake, Yukitsugu; Butler, Rob; Bond, Clare

    2016-04-01

    Interpretation based on seismic reflection data is inherently an uncertain product based on imperfect datasets, with limits in data resolution and spatial extent. This has boosted geologists to use structural validation techniques to verify their seismic interpretations for many years. Structural validation of seismic interpretations should be ideally completed on depth sections, which are converted from time domain using velocities derived from well checkshot survey, seismic velocity analysis, or even estimates. Choices of velocity model critically control the final depth image and hence structural geometry of interpretations that are used as initial datasets for structural validations. However, the depth conversion is never perfectly accurate because of absence of depth constraint. Now, how robust are structural validation techniques to depth conversion uncertainty? Here we explore how structural validation techniques respond to different versions of depth interpretations converted by different velocities. We use a seismic time-based image of a fold-thrust structure in the deepwater Niger Delta to interpret, and convert to depth using three different velocity models: constant velocity (VM1); a single layer having initial velocity v0 at layer top with vertical velocity gradient k (VM2); and three layers having each v0-k set (VM3) below seabed. Forward modelling, automated trishear modelling algorithm called 'inverse trishear modelling' and Groshong's area-depth-strain (ADS) methods are applied to test the structural geometry of the depth-converted interpretations. We find forward modelling and inverse trishear modelling reasonably 'fit' all versions of interpretation, regardless of the velocity model used for depth conversion, with multiple sets of model parameters. On the other hand, only velocity model VM3 'passes' the ADS validation method, with the detachment level interpreted concordant with the depth estimated from excess area analysis, based on interpreted

  3. Variable depth core sampler

    SciTech Connect

    Bourgeois, P.M.; Reger, R.J.

    1994-12-31

    This invention relates to a sampling means, more particularly to a device to sample hard surfaces at varying depths. Often it is desirable to take samples of a hard surface wherein the samples are of the same diameter but of varying depths. Current practice requires that a full top-to-bottom sample of the material be taken, using a hole saw, and boring a hole from one end of the material to the other. The sample thus taken is removed from the hole saw and the middle of said sample is then subjected to further investigation. This paper describes a variable depth core sampler comprimising a circular hole saw member, having longitudinal sections that collapse to form a point and capture a sample, and a second saw member residing inside the first hole saw member to support the longitudinal sections of the first member and prevent them from collapsing to form a point. The second hole saw member may be raised and lowered inside the the first hole saw member.

  4. Performance of scalable coding in depth domain

    NASA Astrophysics Data System (ADS)

    Sjöström, Mårten; Karlsson, Linda S.

    2010-02-01

    Common autostereoscopic 3D displays are based on multi-view projection. The diversity of resolutions and number of views of such displays implies a necessary flexibility of 3D content formats in order to make broadcasting efficient. Furthermore, distribution of content over a heterogeneous network should adapt to an available network capacity. Present scalable video coding provides the ability to adapt to network conditions; it allows for quality, temporal and spatial scaling of 2D video. Scalability for 3D data extends this list to the depth and the view domains. We have introduced scalability with respect to depth information. Our proposed scheme is based on the multi-view-plus-depth format where the center view data are preserved, and side views are extracted in enhancement layers depending on depth values. We investigate the performance of various layer assignment strategies: number of layers, and distribution of layers in depth, either based on equal number of pixels or histogram characteristics. We further consider the consequences to variable distortion due to encoder parameters. The results are evaluated considering their overall distortion verses bit rate, distortion per enhancement layer, as well as visual quality appearance. Scalability with respect to depth (and views) allows for an increased number of quality steps; the cost is a slight increase of required capacity for the whole sequence. The main advantage is, however, an improved quality for objects close to the viewer, even if overall quality is worse.

  5. Depth dependence of vascular fluorescence imaging

    PubMed Central

    Davis, Mitchell A.; Shams Kazmi, S. M.; Ponticorvo, Adrien; Dunn, Andrew K.

    2011-01-01

    In vivo surface imaging of fluorescently labeled vasculature has become a widely used tool for functional brain imaging studies. Techniques such as phosphorescence quenching for oxygen tension measurements and indocyanine green fluorescence for vessel perfusion monitoring rely on surface measurements of vascular fluorescence. However, the depth dependence of the measured fluorescence signals has not been modeled in great detail. In this paper, we investigate the depth dependence of the measured signals using a three-dimensional Monte Carlo model combined with high resolution vascular anatomy. We found that a bulk-vascularization assumption to modeling the depth dependence of the signal does not provide an accurate picture of penetration depth of the collected fluorescence signal in most cases. Instead the physical distribution of microvasculature, the degree of absorption difference between extravascular and intravascular space, and the overall difference in absorption at the excitation and emission wavelengths must be taken into account to determine the depth penetration of the fluorescence signal. Additionally, we found that using targeted illumination can provide for superior surface vessel sensitivity over wide-field illumination, with small area detection offering an even greater amount of sensitivity to surface vasculature. Depth sensitivity can be enhanced by either increasing the detector area or increasing the illumination area. Finally, we see that excitation wavelength and vessel size can affect intra-vessel sampling distribution, as well as the amount of signal that originates from inside the vessel under targeted illumination conditions. PMID:22162824

  6. Comparison of fullerene and large argon clusters for the molecular depth profiling of amino acid multilayers.

    PubMed

    Wehbe, N; Mouhib, T; Delcorte, A; Bertrand, P; Moellers, R; Niehuis, E; Houssiau, L

    2014-01-01

    A major challenge regarding the characterization of multilayer films is to perform high-resolution molecular depth profiling of, in particular, organic materials. This experimental work compares the performance of C60(+) and Ar1700(+) for the depth profiling of model multilayer organic films. In particular, the conditions under which the original interface widths (depth resolution) were preserved were investigated as a function of the sputtering energy. The multilayer samples consisted of three thin δ-layers (~8 nm) of the amino acid tyrosine embedded between four thicker layers (~93 nm) of the amino acid phenylalanine, all evaporated on to a silicon substrate under high vacuum. When C60(+) was used for sputtering, the interface quality degraded with depth through an increase of the apparent width and a decay of the signal intensity. Due to the continuous sputtering yield decline with increasing the C60(+) dose, the second and third δ-layers were shifted with respect to the first one; this deterioration was more pronounced at 10 keV, when the third δ-layer, and a fortiori the silicon substrate, could not be reached even after prolonged sputtering. When large argon clusters, Ar1700(+), were used for sputtering, a stable molecular signal and constant sputtering yield were achieved throughout the erosion process. The depth resolution parameters calculated for all δ-layers were very similar irrespective of the impact energy. The experimental interface widths of approximately 10 nm were barely larger than the theoretical thickness of 8 nm for the evaporated δ-layers.

  7. USGS aerial resolution targets.

    USGS Publications Warehouse

    Salamonowicz, P.H.

    1982-01-01

    It is necessary to measure the achievable resolution of any airborne sensor that is to be used for metric purposes. Laboratory calibration facilities may be inadequate or inappropriate for determining the resolution of non-photographic sensors such as optical-mechanical scanners, television imaging tubes, and linear arrays. However, large target arrays imaged in the field can be used in testing such systems. The USGS has constructed an array of resolution targets in order to permit field testing of a variety of airborne sensing systems. The target array permits any interested organization with an airborne sensing system to accurately determine the operational resolution of its system. -from Author

  8. Volumetric retinal fluorescence microscopic imaging with extended depth of field

    NASA Astrophysics Data System (ADS)

    Li, Zengzhuo; Fischer, Andrew; Li, Wei; Li, Guoqiang

    2016-03-01

    Wavefront-engineered microscope with greatly extended depth of field (EDoF) is designed and demonstrated for volumetric imaging with near-diffraction limited optical performance. A bright field infinity-corrected transmissive/reflective light microscope is built with Kohler illumination. A home-made phase mask is placed in between the objective lens and the tube lens for ease of use. General polynomial function is adopted in the design of the phase plate for robustness and custom merit function is used in Zemax for optimization. The resulting EDoF system achieves an engineered point spread function (PSF) that is much less sensitive to object depth variation than conventional systems and therefore 3D volumetric information can be acquired in a single frame with expanded tolerance of defocus. In Zemax simulation for a setup using 32X objective (NA = 0.6), the EDoF is 20μm whereas a conventional one has a DoF of 1.5μm, indicating a 13 times increase. In experiment, a 20X objective lens with NA = 0.4 was used and the corresponding phase plate was designed and fabricated. Retinal fluorescence images of the EDoF microscope using passive adaptive optical phase element illustrate a DoF around 100μm and it is able to recover the volumetric fluorescence images that are almost identical to in-focus images after post processing. The image obtained from the EDoF microscope is also better in resolution and contrast, and the retinal structure is better defined. Hence, due to its high tolerance of defocus and fine restored image quality, EDoF optical systems have promising potential in consumer portable medical imaging devices where user's ability to achieve focus is not optimal, and other medical imaging equipment where achieving best focus is not a necessary.

  9. Depth-encoded synthetic aperture optical coherence tomography of biological tissues with extended focal depth.

    PubMed

    Mo, Jianhua; de Groot, Mattijs; de Boer, Johannes F

    2015-02-23

    Optical coherence tomography (OCT) has proven to be able to provide three-dimensional (3D) volumetric images of scattering biological tissues for in vivo medical diagnostics. Unlike conventional optical microscopy, its depth-resolving ability (axial resolution) is exclusively determined by the laser source and therefore invariant over the full imaging depth. In contrast, its transverse resolution is determined by the objective's numerical aperture and the wavelength which is only approximately maintained over twice the Rayleigh range. However, the prevailing laser sources for OCT allow image depths of more than 5 mm which is considerably longer than the Rayleigh range. This limits high transverse resolution imaging with OCT. Previously, we reported a novel method to extend the depth-of-focus (DOF) of OCT imaging in Mo et al.Opt. Express 21, 10048 (2013)]. The approach is to create three different optical apertures via pupil segmentation with an annular phase plate. These three optical apertures produce three OCT images from the same sample, which are encoded to different depth positions in a single OCT B-scan. This allows for correcting the defocus-induced curvature of wave front in the pupil so as to improve the focus. As a consequence, the three images originating from those three optical apertures can be used to reconstruct a new image with an extended DOF. In this study, we successfully applied this method for the first time to both an artificial phantom and biological tissues over a four times larger depth range. The results demonstrate a significant DOF improvement, paving the way for 3D high resolution OCT imaging beyond the conventional Rayleigh range. PMID:25836528

  10. A variety of vertical integration process for high resolution seismic imaging

    NASA Astrophysics Data System (ADS)

    Tong, S.; Liu, Y., Sr.; Wen, J.

    2015-12-01

    Seismic prospecting, including long array multichannel seismic prospecting, ultrahigh resolution shallow profile prospecting and short trace interval short array high resolution multichannel seismic prospecting, make a great contribution to discover the marine oil-gas field. Seismic data have different dominant frequencies, resolution and penetration depth for different exploration purposes and methods. In seismic prospecting the long array has shot-receiver offset over several kilometers. Its trace interval and shot interval is about some decameters, while the dominant frequency is tens of hertz. Its penetration depth is thousands of meters. Its order of resolution in vertical and horizontal is meters to decameters. Ultrahigh resolution shallow profile prospecting data is used at well site and later for risk assessment with sonar data. We need its vertical and horizontal resolution come to at least decimeter level. Its frequency is about thousands hertz and penetration depth is about decameters. Small-interval, short array, high resolution multichannel seismic prospecting has compromise effect between long array multichannel seismic prospecting and ultrahigh resolution shallow profile prospecting. We can use this to link up long array multichannel seismic prospecting and ultrahigh resolution shallow profile prospecting vertically. By mixing these different frequency seismic data one can maximize the advantages of these data. Since different seismic data can only achieve certain level of accuracy and quality in seismic imaging, there is no perfect method to process these data in vertical direction. Here, we propose to mix those data and achieve the integrated seismic processing. Base on mixing different seismic data, the cooperative process can take the advantage of mixing data to image different target layers. With this method we can lay bare mysteries of ocean bottom and deeper layer, provide assistance to find oil and gas, and provide services for oil-gas field

  11. Optimization of Variable-Depth Liner Configurations for Increased Broadband Noise Reduction

    NASA Technical Reports Server (NTRS)

    Jones, M. G.; Watson, W. R.; Nark, D. M.; Schiller, N. H.; Born, J. C.

    2016-01-01

    This paper employs three acoustic propagation codes to explore variable-depth liner configurations for the NASA Langley Grazing Flow Impedance Tube (GFIT). The initial study demonstrates that a variable impedance can acceptably be treated as a uniform impedance if the spatial extent over which this variable impedance occurs is less than one-third of a wavelength of the incident sound. A constrained optimization study is used to design a variable-depth liner and to select an optimization metric. It also provides insight regarding how much attenuation can be achieved with variable-depth liners. Another optimization study is used to design a liner with much finer chamber depth resolution for the Mach 0.0 and 0.3 test conditions. Two liners are designed based on spatial rearrangement of chambers from this liner to determine whether the order is critical. Propagation code predictions suggest this is not the case. Both liners are fabricated via additive manufacturing and tested in the GFIT for the Mach 0.0 condition. Predicted and measured attenuations compare favorably across the full frequency range. These results clearly suggest that the chambers can be arranged in any order, thus offering the potential for innovative liner designs to minimize depth and weight.

  12. Depth of Field Analysis for Multilayer Automultiscopic Displays

    NASA Astrophysics Data System (ADS)

    Lanman, D.; Wetzstein, G.; Hirsch, M.; Raskar, R.

    2013-02-01

    With the re-emergence of stereoscopic displays, through polarized glasses for theatrical presentations and shuttered liquid crystal eyewear in the home, automultiscopic displays have received increased attention. Commercial efforts have predominantly focused on parallax barrier and lenticular architectures applied to LCD panels. Such designs suffer from reduced resolution and brightness. Recently, multilayer LCDs have emerged as an alternative supporting full-resolution imagery with enhanced brightness and depth of field. We present a signal-processing framework for comparing the depth of field for conventional automultiscopic displays and emerging architectures comprising multiple light-attenuating layers. We derive upper bounds for the depths of field, indicating the potential of multilayer configurations to significantly enhance resolution and depth of field, relative to conventional designs.

  13. High resolution multiplexed functional imaging in live embyros (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Xu, Dongli; Peng, Leilei

    2016-03-01

    Optical projection tomography (OPT) creates isotropic 3D imaging of tissue. Two approaches exist today: Wide-field OPT illuminates the entire sample and acquires projection images with a camera; Scanning-laser optical tomography (SLOT) generates the projection with a moving laser beam and point detector. SLOT has superior light collecting efficiency than wide-field optical tomography, making it ideal for tissue fluorescence imaging. Regardless the approach, traditional OPT has to compromise between the resolution and the depth of view. In traditional SLOT, the focused Gaussian beam diverges quickly from the focused plane, making it impossible to achieve high resolution imaging through a large volume specimen. We report using Bessel beam instead of Gaussian beam to perform SLOT. By illuminating samples with a narrow Bessel beam throughout an extended depth, high-resolution projection images can be measured in large volume. Under Bessel illumination, the projection image contains signal from annular-rings of the Bessel beam. Traditional inverse Radon transform of these projections will result in ringing artifacts in reconstructed imaging. Thus a modified 3D filtered back projection algorithm is developed to perform tomography reconstructing of Bessel-illuminated projection images. The resulting 3D imaging is free of artifact and achieved cellular resolution in extended sample volume. The system is applied to in-vivo imaging of transgenic Zebrafish embryos. Results prove Bessel SLOT a promising imaging method in development biology research.

  14. Efficient multiview depth video coding using depth synthesis prediction

    NASA Astrophysics Data System (ADS)

    Lee, Cheon; Choi, Byeongho; Ho, Yo-Sung

    2011-07-01

    The view synthesis prediction (VSP) method utilizes interview correlations between views by generating an additional reference frame in the multiview video coding. This paper describes a multiview depth video coding scheme that incorporates depth view synthesis and additional prediction modes. In the proposed scheme, we exploit the reconstructed neighboring depth frame to generate an additional reference depth image for the current viewpoint to be coded using the depth image-based-rendering technique. In order to generate high-quality reference depth images, we used pre-processing on depth, depth image warping, and two types of hole filling methods depending on the number of available reference views. After synthesizing the additional depth image, we encode the depth video using the proposed additional prediction modes named VSP modes; those additional modes refer to the synthesized depth image. In particular, the VSP_SKIP mode refers to the co-located block of the synthesized frame without the coding motion vectors and residual data, which gives most of the coding gains. Experimental results demonstrate that the proposed depth view synthesis method provides high-quality depth images for the current view and the proposed VSP modes provide high coding gains, especially on the anchor frames.

  15. Depth-aware image seam carving.

    PubMed

    Shen, Jianbing; Wang, Dapeng; Li, Xuelong

    2013-10-01

    Image seam carving algorithm should preserve important and salient objects as much as possible when changing the image size, while not removing the secondary objects in the scene. However, it is still difficult to determine the important and salient objects that avoid the distortion of these objects after resizing the input image. In this paper, we develop a novel depth-aware single image seam carving approach by taking advantage of the modern depth cameras such as the Kinect sensor, which captures the RGB color image and its corresponding depth map simultaneously. By considering both the depth information and the just noticeable difference (JND) model, we develop an efficient JND-based significant computation approach using the multiscale graph cut based energy optimization. Our method achieves the better seam carving performance by cutting the near objects less seams while removing distant objects more seams. To the best of our knowledge, our algorithm is the first work to use the true depth map captured by Kinect depth camera for single image seam carving. The experimental results demonstrate that the proposed approach produces better seam carving results than previous content-aware seam carving methods. PMID:23893762

  16. Depth profiling of tritium in materials for fusion technology

    SciTech Connect

    Sawicki, J.A.

    1988-09-01

    The paper outlines recent progress in depth profiling of tritium distribution near the surface of materials by two ion beam techniques; elastic recoil detection (ERD) and T(d,/alpha/)n nuclear reaction analysis (NRA). The sensitivity and depth-resolution of both methods are examined for a series of tritiated titanium films. Calculated depth profiles and ranges of implanted tritium ions in selected candidate materials for thermonuclear fusion devices are also given. Depth profiles of tritium implanted into specimens of graphite and lithium oxides as a function of temperature are discussed as the examples of applications.

  17. Ultra-long scan depth optical coherence tomography for imaging the anterior segment of human eye

    NASA Astrophysics Data System (ADS)

    Zhu, Dexi; Shen, Meixiao; Leng, Lin

    2012-12-01

    Spectral domain optical coherence tomography (SD-OCT) was developed in order to image the anterior segment of human eye. The optical path at reference arm was switched to compensate the sensitivity drop in OCT images. An scan depth of 12.28 mm and an axial resolution of 12.8 μm in air were achieved. The anterior segment from cornea to posterior surface of crystalline lens was clearly imaged and measured using this system. A custom designed Badal optometer was coupled into the sample arm to induce the accommodation, and the movement of crystalline lens was traced after the image registration. Our research demonstrates that SD-OCT with ultra-long scan depth can be used to image the human eye for accommodation research.

  18. Natural fracturing, by depth

    NASA Astrophysics Data System (ADS)

    Hooker, John; Laubach, Stephen

    2013-04-01

    Natural opening-mode fractures commonly fall upon a spectrum whose end-members are veins, which have wide ranges of sizes and are mostly or thoroughly cemented, and joints, which have little opening displacement and little or no cement. The vein end-member is common in metamorphic rocks, whose high temperature and pressure of formation place them outside typical reservoir settings; conversely, many uncemented joints likely form near the surface and so too have limited relevance to subsurface exploration. Sampling of cores retrieved from tight-gas sandstone reservoirs suggest that it is intermediate fractures, not true joints or veins, that provide natural porosity and permeability. Such fractures have abundant pore space among fracture-bridging cements, which may hold fractures open despite varying states of stress through time. Thus the more sophisticated our understanding of the processes that form veins and joints, i.e., how natural fracturing varies by depth, the better our ability to predict intermediate fractures. Systematic differences between veins and joints, in terms of size-scaling and lateral and stratigraphic spatial arrangement, have been explained in the literature by the mechanical effects of sedimentary layering, which likely exert more control over fracture patterns at shallower depths. Thus stratabound joints commonly have narrow size ranges and regular spacing; non-stratabound veins have a wide range of sizes and spacings. However, new fieldwork and careful literature review suggest that the effects of mechanical layering are only half the story. Although atypical, veins may be highly stratabound and yet spatially clustered; non-stratabound fractures may nonetheless feature narrow size ranges. These anomalous fracture arrangements are better explained by the presence of precipitating cements during fracture opening than by mechanical layering. Cement is thought to be highly important for fracture permeability, but potential effects of

  19. Enhanced High Resolution RBS System

    NASA Astrophysics Data System (ADS)

    Pollock, Thomas J.; Hass, James A.; Klody, George M.

    2011-06-01

    Improvements in full spectrum resolution with the second NEC high resolution RBS system are summarized. Results for 50 Å TiN/HfO films on Si yielding energy resolution on the order of 1 keV are also presented. Detector enhancements include improved pulse processing electronics, upgraded shielding for the MCP/RAE detector, and reduced noise generated from pumping. Energy resolution measurements on spectra front edge coupled with calculations using 0.4mStr solid angle show that beam energy spread at 400 KeV from the Pelletron® accelerator is less than 100 eV. To improve user throughput, magnet control has been added to the automatic data collection. Depth profiles derived from experimental data are discussed. For the thin films profiled, depth resolutions were on the Angstrom level with the non-linear energy/channel conversions ranging from 100 to 200 eV.

  20. Whole-animal imaging with high spatio-temporal resolution

    NASA Astrophysics Data System (ADS)

    Chhetri, Raghav; Amat, Fernando; Wan, Yinan; Höckendorf, Burkhard; Lemon, William C.; Keller, Philipp J.

    2016-03-01

    We developed isotropic multiview (IsoView) light-sheet microscopy in order to image fast cellular dynamics, such as cell movements in an entire developing embryo or neuronal activity throughput an entire brain or nervous system, with high resolution in all dimensions, high imaging speeds, good physical coverage and low photo-damage. To achieve high temporal resolution and high spatial resolution at the same time, IsoView microscopy rapidly images large specimens via simultaneous light-sheet illumination and fluorescence detection along four orthogonal directions. In a post-processing step, these four views are then combined by means of high-throughput multiview deconvolution to yield images with a system resolution of ≤ 450 nm in all three dimensions. Using IsoView microscopy, we performed whole-animal functional imaging of Drosophila embryos and larvae at a spatial resolution of 1.1-2.5 μm and at a temporal resolution of 2 Hz for up to 9 hours. We also performed whole-brain functional imaging in larval zebrafish and multicolor imaging of fast cellular dynamics across entire, gastrulating Drosophila embryos with isotropic, sub-cellular resolution. Compared with conventional (spatially anisotropic) light-sheet microscopy, IsoView microscopy improves spatial resolution at least sevenfold and decreases resolution anisotropy at least threefold. Compared with existing high-resolution light-sheet techniques, such as lattice lightsheet microscopy or diSPIM, IsoView microscopy effectively doubles the penetration depth and provides subsecond temporal resolution for specimens 400-fold larger than could previously be imaged.

  1. Super resolution fluorescence microscopy

    PubMed Central

    Huang, Bo; Bates, Mark; Zhuang, Xiaowei

    2010-01-01

    Achieving a spatial resolution that is not limited by the diffraction of light, recent developments of super-resolution fluorescence microscopy techniques allow the observation of many biological structures not resolvable in conventional fluorescence microscopy. New advances in these techniques now give them the ability to image three-dimensional (3D) structures, measure interactions by multicolor colocalization, and record dynamic processes in living cells at the nanometer scale. It is anticipated that super-resolution fluorescence microscopy will become a widely used tool for cell and tissue imaging to provide previously unobserved details of biological structures and processes. PMID:19489737

  2. Lunar Regolith Depths from LROC Images

    NASA Astrophysics Data System (ADS)

    Bart, Gwendolyn D.; Nickerson, R.; Lawder, M.

    2010-10-01

    Since the 1960's, most lunar photography and science covered the equatorial near side where the Apollo spacecraft landed. As a result, our understanding of lunar regolith depth was also limited to that region. Oberbeck and Quaide (JGR 1968) found regolith depths for the lunar near side: 3 m (Oceanus Procellarum), 16 m (Hipparchus), and 1-10 m at the Surveyor landing sites. The Lunar Reconnaissance Orbiter Camera recently released high resolution images that sample regions all around the lunar globe. We examined a selection of these images across the lunar globe and determined a regolith depth for each area. To do this, we measured the ratio of the diameter of the flat floor to the diameter of the crater, and used it to calculate the regolith thickness using the method of Quaide and Oberbeck (JGR 1968). Analysis of the global distribution of lunar regolith depths will provide new insights into the evolution of the lunar surface and the frequency, distribution, and effect of impacts.

  3. In-depth fiber optic two-photon polymerization and its applications in micromanipulation

    NASA Astrophysics Data System (ADS)

    Mishra, Yogeshwar N.; Ingle, Ninad D.; Pinto, Mervyn; Mohanty, Samarendra K.

    2011-02-01

    Two photon polymerization (TPP) has enabled three-dimensional microfabrication with sub-diffraction limited spatial resolution. However, depth at which TPP could be achieved, has been limited due to the high numerical aperture microscope objective, used to focus the ultrafast laser beam. Here, we report fiber-optic two photon polymerization (FTP) for in-depth fabrication of microstructures from a photopolymerizable resin. A cleaved single mode optical fiber coupled with tunable femtosecond laser could achieve TPP, forming extended waveguide on the fiber itself. The length of the FTP tip was found to depend on the laser power and exposure duration. Microfabricated fiber tip using FTP was employed to deliver continuous wave laser beam on to polystyrene microspheres in order to transport and manipulate selected particles by scattering force and 2D trapping. Such microstructures formed by TPP on tip of the fiber will also enable puncture and micro-surgery of cellular structures. With use of a cleaved fiber or axicon tip, FTP structures were fabricated on curved surfaces at large depth. The required Power for FTP and the polymerization rate was faster while using an axicon tip optical fiber. This enabled fabrication of complex octopus-like microstructures.

  4. Depth profilometry via multiplexed optical high-coherence interferometry.

    PubMed

    Kazemzadeh, Farnoud; Wong, Alexander; Behr, Bradford B; Hajian, Arsen R

    2015-01-01

    Depth Profilometry involves the measurement of the depth profile of objects, and has significant potential for various industrial applications that benefit from non-destructive sub-surface profiling such as defect detection, corrosion assessment, and dental assessment to name a few. In this study, we investigate the feasibility of depth profilometry using an Multiplexed Optical High-coherence Interferometry MOHI instrument. The MOHI instrument utilizes the spatial coherence of a laser and the interferometric properties of light to probe the reflectivity as a function of depth of a sample. The axial and lateral resolutions, as well as imaging depth, are decoupled in the MOHI instrument. The MOHI instrument is capable of multiplexing interferometric measurements into 480 one-dimensional interferograms at a location on the sample and is built with axial and lateral resolutions of 40 μm at a maximum imaging depth of 700 μm. Preliminary results, where a piece of sand-blasted aluminum, an NBK7 glass piece, and an optical phantom were successfully probed using the MOHI instrument to produce depth profiles, demonstrate the feasibility of such an instrument for performing depth profilometry. PMID:25803289

  5. Depth Profilometry via Multiplexed Optical High-Coherence Interferometry

    PubMed Central

    Kazemzadeh, Farnoud; Wong, Alexander; Behr, Bradford B.; Hajian, Arsen R.

    2015-01-01

    Depth Profilometry involves the measurement of the depth profile of objects, and has significant potential for various industrial applications that benefit from non-destructive sub-surface profiling such as defect detection, corrosion assessment, and dental assessment to name a few. In this study, we investigate the feasibility of depth profilometry using an Multiplexed Optical High-coherence Interferometry MOHI instrument. The MOHI instrument utilizes the spatial coherence of a laser and the interferometric properties of light to probe the reflectivity as a function of depth of a sample. The axial and lateral resolutions, as well as imaging depth, are decoupled in the MOHI instrument. The MOHI instrument is capable of multiplexing interferometric measurements into 480 one-dimensional interferograms at a location on the sample and is built with axial and lateral resolutions of 40 μm at a maximum imaging depth of 700 μm. Preliminary results, where a piece of sand-blasted aluminum, an NBK7 glass piece, and an optical phantom were successfully probed using the MOHI instrument to produce depth profiles, demonstrate the feasibility of such an instrument for performing depth profilometry. PMID:25803289

  6. Automatic detection of position and depth of potential UXO using continuous wavelet transforms

    NASA Astrophysics Data System (ADS)

    Billings, Stephen D.; Herrmann, Felix J.

    2003-09-01

    Inversion algorithms for UXO discrimination using magnetometery have recently been used to achieve very low False Alarm Rates, with 100% recovery of detected ordnance. When there are many UXO and/or when the UXO are at significantly different depths, manual estimation of the initial position and scale for each item, is a laborious and time-consuming process. In this paper, we utilize the multi-resolution properties of wavelets to automatically estimate both the position and scale of dipole peaks. The Automated Wavelet Detection (AWD) algorithm that we develop consists of four-stages: (i) maxima and minima in the data are followed across multiple scales as we zoom with a continuous wavelet transform; (ii) the decay of the amplitude of each peak with scale is used to estimate the depth to source; (iii) adjacent maxima and minima of comparable depth are joined together to form dipole anomalies; and (iv) the relative positions and amplitudes of the extrema, along with their depths, are used to estimate a dipole model. We demonstrate the application of the AWD algorithm to three datasets with different characteristics. In each case, the method rapidly located the majority of dipole anomalies and produced accurate estimates of dipole parameters.

  7. A practical block detector for a depth encoding PET camera

    SciTech Connect

    Rogers, J.G.; Moisan, C.; Hoskinson, E.M.; Andreaco, M.S.; Williams, C.W.; Nutt, A.

    1995-10-01

    The depth-of-interaction effect in block detectors degrades the image resolution in commercial PET cameras and impedes the natural evolution of smaller, less expensive cameras. A method for correcting the measured position of each detected gamma ray by measuring its depth-of-interaction was tested and found to recover 38% of the lost resolution in a table-top 50 cm diameter camera. To obtain the desired depth sensitivity, standard commercial detectors were modified by a simple and practical process, which is suitable for mass production of the detectors. The impact of the detector modifications on central image resolution and on the ability of the camera to correct for object scatter were also measured.

  8. THEMIS Observations of Atmospheric Aerosol Optical Depth

    NASA Technical Reports Server (NTRS)

    Smith, Michael D.; Bandfield, Joshua L.; Christensen, Philip R.; Richardson, Mark I.

    2003-01-01

    The Mars Odyssey spacecraft entered into Martian orbit in October 2001 and after successful aerobraking began mapping in February 2002 (approximately Ls=330 deg.). Images taken by the Thermal Emission Imaging System (THEMIS) on-board the Odyssey spacecraft allow the quantitative retrieval of atmospheric dust and water-ice aerosol optical depth. Atmospheric quantities retrieved from THEMIS build upon existing datasets returned by Mariner 9, Viking, and Mars Global Surveyor (MGS). Data from THEMIS complements the concurrent MGS Thermal Emission Spectrometer (TES) data by offering a later local time (approx. 2:00 for TES vs. approx. 4:00 - 5:30 for THEMIS) and much higher spatial resolution.

  9. Bessel beam Grueneisen photoacoustic microscopy with extended depth of field

    NASA Astrophysics Data System (ADS)

    Shi, Junhui; Wang, Lidai; Noordam, Cedric; Wang, Lihong V.

    2016-03-01

    The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction-free, provides a long focal depth, but its side-lobes may deteriorate image quality when the Bessel beam is directly employed to excite photoacoustic signals in ORPAM. Here, we present a nonlinear approach based on the Grueneisen relaxation effect to suppress the side-lobe artifacts in photoacoustic imaging. This method extends the focal depth of OR-PAM and speeds up volumetric imaging. We experimentally demonstrated a 1-mm focal depth with a 7-μm lateral resolution and volumetrically imaged a carbon fiber and red blood cell samples.

  10. High resolution drift chambers

    SciTech Connect

    Va'vra, J.

    1985-07-01

    High precision drift chambers capable of achieving less than or equal to 50 ..mu..m resolutions are discussed. In particular, we compare so called cool and hot gases, various charge collection geometries, several timing techniques and we also discuss some systematic problems. We also present what we would consider an ''ultimate'' design of the vertex chamber. 50 refs., 36 figs., 6 tabs.

  11. [Dispute Resolutions].

    ERIC Educational Resources Information Center

    Hale, Claudia L.; Cooks, Leda M.

    1994-01-01

    Focusing on the teaching of alternative dispute resolutions at universities, Claudia L. Hale and Leda M. Cooks argue that mediation should be taught primarily as a communication process that involves the joint efforts of mediator and disputants. Teachers of mediation should begin by distinguishing mediation from other forms of dispute resolution,…

  12. High Spectral Resolution Lidar Data

    DOE Data Explorer

    Eloranta, Ed

    2004-12-01

    The HSRL provided calibrated vertical profiles of optical depth, backscatter cross section and depoloarization at a wavelength of 532 nm. Profiles were acquired at 2.5 second intervals with 7.5 meter resolution. Profiles extended from an altitude of 100 m to 30 km in clear air. The lidar penetrated to a maximum optical depth of ~ 4 under cloudy conditions. Our data contributed directly to the aims of the M-PACE experiment, providing calibrated optical depth and optical backscatter measurements which were not available from any other instrument.

  13. Wind profiler mixing depth and entrainment measurements with chemical applications

    SciTech Connect

    Angevine, W.M.; Trainer, M.; Parrish, D.D.; Buhr, M.P.; Fehsenfeld, F.C.; Kok, G.L.

    1994-12-31

    Wind profiling radars operating at 915 MHz have been present at a number of regional air quality studies. The profilers can provide a continuous, accurate record of the depth of the convective mixed layer with good time resolution. Profilers also provide information about entrainment at the boundary layer top. Mixing depth data from several days of the Rural Oxidants in the Southern Environment II (ROSE II) study in Alabama in June, 1992 are presented. For several cases, chemical measurements from aircraft and ground-based instruments are shown to correspond to mixing depth and entrainment zone behavior observed by the profiler.

  14. Perception of relative depth interval: systematic biases in perceived depth.

    PubMed

    Harris, Julie M; Chopin, Adrien; Zeiner, Katharina; Hibbard, Paul B

    2012-01-01

    Given an estimate of the binocular disparity between a pair of points and an estimate of the viewing distance, or knowledge of eye position, it should be possible to obtain an estimate of their depth separation. Here we show that, when points are arranged in different vertical geometric configurations across two intervals, many observers find this task difficult. Those who can do the task tend to perceive the depth interval in one configuration as very different from depth in the other configuration. We explore two plausible explanations for this effect. The first is the tilt of the empirical vertical horopter: Points perceived along an apparently vertical line correspond to a physical line of points tilted backwards in space. Second, the eyes can rotate in response to a particular stimulus. Without compensation for this rotation, biases in depth perception would result. We measured cyclovergence indirectly, using a standard psychophysical task, while observers viewed our depth configuration. Biases predicted from error due either to cyclovergence or to the tilted vertical horopter were not consistent with the depth configuration results. Our data suggest that, even for the simplest scenes, we do not have ready access to metric depth from binocular disparity.

  15. Conflicts and communication between high-achieving Chinese American adolescents and their parents.

    PubMed

    Qin, Desiree Baolian; Chang, Tzu-Fen; Han, Eun-Jin; Chee, Grace

    2012-01-01

    Drawing on in-depth interview data collected on 18 high-achieving Chinese American students, the authors examine domains of acculturation-based conflicts, parent and child internal conflicts, and conflict resolution in their families. Their analyses show that well-established negative communication patterns in educational expectations, divergent attitudes toward other races and country of origin, and cultural and language barriers contributed to parent-child conflicts. Their findings also illustrate important internal conflicts both adolescents and parents had along the cultural tightrope of autonomy and relatedness. Finally, the vertical in-group conflict resolution style that was evidenced in youths' accounts raises questions about cultural differences in constructive versus destructive conflict resolution styles.

  16. Microphysical and Dynamical Influences on Cirrus Cloud Optical Depth Distributions

    SciTech Connect

    Kay, J.; Baker, M.; Hegg, D.

    2005-03-18

    Cirrus cloud inhomogeneity occurs at scales greater than the cirrus radiative smoothing scale ({approx}100 m), but less than typical global climate model (GCM) resolutions ({approx}300 km). Therefore, calculating cirrus radiative impacts in GCMs requires an optical depth distribution parameterization. Radiative transfer calculations are sensitive to optical depth distribution assumptions (Fu et al. 2000; Carlin et al. 2002). Using raman lidar observations, we quantify cirrus timescales and optical depth distributions at the Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) site in Lamont, OK (USA). We demonstrate the sensitivity of outgoing longwave radiation (OLR) calculations to assumed optical depth distributions and to the temporal resolution of optical depth measurements. Recent work has highlighted the importance of dynamics and nucleation for cirrus evolution (Haag and Karcher 2004; Karcher and Strom 2003). We need to understand the main controls on cirrus optical depth distributions to incorporate cirrus variability into model radiative transfer calculations. With an explicit ice microphysics parcel model, we aim to understand the influence of ice nucleation mechanism and imposed dynamics on cirrus optical depth distributions.

  17. Plenoptic depth map in the case of occlusions

    NASA Astrophysics Data System (ADS)

    Yu, Zhan; Yu, Jingyi; Lumsdaine, Andrew; Georgiev, Todor

    2013-03-01

    Recent realizations of hand-held plenoptic cameras have given rise to previously unexplored effects in photography. Designing a mobile phone plenoptic camera is becoming feasible with the significant increase of computing power of mobile devices and the introduction of System on a Chip. However, capturing high numbers of views is still impractical due to special requirements such as ultra-thin camera and low costs. In this paper, we analyze a mobile plenoptic camera solution with a small number of views. Such a camera can produce a refocusable high resolution final image if a depth map is generated for every pixel in the sparse set of views. With the captured multi-view images, the obstacle to recovering a high-resolution depth is occlusions. To robustly resolve these, we first analyze the behavior of pixels in such situations. We show that even under severe occlusion, one can still distinguish different depth layers based on statistics. We estimate the depth of each pixel by discretizing the space in the scene and conducting plane sweeping. Specifically, for each given depth, we gather all corresponding pixels from other views and model the in-focus pixels as a Gaussian distribution. We show how it is possible to distinguish occlusion pixels, and in-focus pixels in order to find the depths. Final depth maps are computed in real scenes captured by a mobile plenoptic camera.

  18. A new method for depth of interaction determination in PET detectors.

    PubMed

    Pizzichemi, M; Stringhini, G; Niknejad, T; Liu, Z; Lecoq, P; Tavernier, S; Varela, J; Paganoni, M; Auffray, E

    2016-06-21

    A new method for obtaining depth of interaction (DOI) information in PET detectors is presented in this study, based on sharing and redirection of scintillation light among multiple detectors, together with attenuation of light over the length of the crystals. The aim is to obtain continuous DOI encoding with single side readout, and at the same time without the need for one-to-one coupling between scintillators and detectors, allowing the development of a PET scanner with good spatial, energy and timing resolutions while keeping the complexity of the system low. A prototype module has been produced and characterized to test the proposed method, coupling a LYSO scintillator matrix to a commercial SiPMs array. Excellent crystal separation is obtained for all the scintillators in the array, light loss due to depolishing is found to be negligible, energy resolution is shown to be on average 12.7% FWHM. The mean DOI resolution achieved is 4.1 mm FWHM on a 15 mm long crystal and preliminary coincidence time resolution was estimated in 353 ps FWHM. PMID:27245174

  19. A new method for depth of interaction determination in PET detectors

    NASA Astrophysics Data System (ADS)

    Pizzichemi, M.; Stringhini, G.; Niknejad, T.; Liu, Z.; Lecoq, P.; Tavernier, S.; Varela, J.; Paganoni, M.; Auffray, E.

    2016-06-01

    A new method for obtaining depth of interaction (DOI) information in PET detectors is presented in this study, based on sharing and redirection of scintillation light among multiple detectors, together with attenuation of light over the length of the crystals. The aim is to obtain continuous DOI encoding with single side readout, and at the same time without the need for one-to-one coupling between scintillators and detectors, allowing the development of a PET scanner with good spatial, energy and timing resolutions while keeping the complexity of the system low. A prototype module has been produced and characterized to test the proposed method, coupling a LYSO scintillator matrix to a commercial SiPMs array. Excellent crystal separation is obtained for all the scintillators in the array, light loss due to depolishing is found to be negligible, energy resolution is shown to be on average 12.7% FWHM. The mean DOI resolution achieved is 4.1 mm FWHM on a 15 mm long crystal and preliminary coincidence time resolution was estimated in 353 ps FWHM.

  20. Curie Depth Analysis of the Salton Sea Region, Southern California

    NASA Astrophysics Data System (ADS)

    Mickus, Kevin; Hussein, Musa

    2016-02-01

    Aeromagnetic data were analyzed to determine the bottom of magnetic bodies that might be related to the Curie point depth (CPD) by 2D spectral and 3D inversion methods within the Salton Trough and the surrounding region in southern California. The bottom of the magnetic bodies for 55 × 55 km windows varied in depth between 11 and 23 km in depth using 2D spectral methods. Since the 55 × 55 km square window may include both shallow and deep source, a 3D inversion method was used to provide better resolution of the bottom of the magnetic bodies. The 3D models indicate the depth to the bottom of the magnetic bodies varied between 5 and 23 km. Even though both methods produced similar results, the 3D inversion method produced higher resolution of the CPD depths. The shallowest depths (5-8 km) occur along and west of the Brawley Seismic Zone and the southwestern portion of the Imperial Valley. The source of these shallow CPD values may be related to geothermal systems including hydrothermal circulation and/or partially molten material. Additionally, shallow CPD depths (7-12 km) were found in a northwest-trending zone in the center of the Salton Trough. These depths coincide with previous seismic analyses that indicated a lower crustal low velocity region which is believed to be caused by partially molten material. Lower velocity zones in several regions may be related to fracturing and/or hydrothermal fluids. If the majority of these shallow depths are related to temperature, they are likely associated with the CPD, and the partially molten material extends over a wider zone than previously known. Greater depths within the Salton Trough coincide with the base of basaltic material and/or regions of intense metamorphism intruded by mafic material in the middle/lower crust.

  1. Matched-field depth estimation for active sonar.

    PubMed

    Hickman, Granger; Krolik, Jeffrey L

    2004-02-01

    This work concerns the problem of estimating the depth of a submerged scatterer in a shallow-water ocean by using an active sonar and a horizontal receiver array. As in passive matched-field processing (MFP) techniques, numerical modeling of multipath propagation is used to facilitate localization. However, unlike passive MFP methods where estimation of source range is critically dependent on relative modal phase modeling, in active sonar source range is approximately known from travel-time measurements. Thus the proposed matched-field depth estimation (MFDE) method does not require knowledge of the complex relative multipath amplitudes which also depend on the unknown scatterer characteristics. Depth localization is achieved by modeling depth-dependent relative delays and elevation angle spreads between multipaths. A maximum likelihood depth estimate is derived under the assumption that returns from a sequence of pings are uncorrelated and the scatterer is at constant depth. The Cramér-Rao lower bound on depth estimation mean-square-error is computed and compared with Monte Carlo simulation results for a typical range-dependent, shallow-water Mediterranean environment. Depth estimation performance to within 10% of the water column depth is predicted at signal-to-noise ratios of greater than 10 dB. Real data results are reported for depth estimation of an echo repeater to within 10-m accuracy in this same shallow water environment.

  2. Depth-resolved ballistic imaging in a low-depth-of-field optical Kerr gated imaging system

    NASA Astrophysics Data System (ADS)

    Zheng, Yipeng; Tan, Wenjiang; Si, Jinhai; Ren, YuHu; Xu, Shichao; Tong, Junyi; Hou, Xun

    2016-09-01

    We demonstrate depth-resolved imaging in a ballistic imaging system, in which a heterodyned femtosecond optical Kerr gate is introduced to extract useful imaging photons for detecting an object hidden in turbid media and a compound lens is proposed to ensure both the depth-resolved imaging capability and the long working distance. Two objects of about 15-μm widths hidden in a polystyrene-sphere suspension have been successfully imaged with approximately 600-μm depth resolution. Modulation-transfer-function curves with the object in and away from the object plane have also been measured to confirm the depth-resolved imaging capability of the low-depth-of-field (low-DOF) ballistic imaging system. This imaging approach shows potential for application in research of the internal structure of highly scattering fuel spray.

  3. Temporal resolution enhancement from motion

    NASA Astrophysics Data System (ADS)

    Rollason, M. P.; Watson, G. H.; Strens, M. J. A.

    2009-09-01

    We describe progress in the third year of the EMRS DTC TEP theme project entitled "Temporal Resolution Enhancement from Motion". The aim is to develop algorithms that combine evidence over time from a sequence of images in order to improve spatial resolution and reduce unwanted artefacts. Years one and two of this project developed and demonstrated an efficient algorithm that provided good resolution enhancement of a scene viewed in the far field (approximately flat) [1]. This paper reports a new algorithm which is applicable to a three dimensional scene where substantial depth variation causes parallax within the imagery. The new algorithm is demonstrated using airborne infra-red imagery.

  4. Lensfree on-chip high-resolution imaging using two-way lighting, and its limitations

    NASA Astrophysics Data System (ADS)

    Adachi, Yasuhiko; Tamaki, Tokuhiko; Motomura, Hideto; Kato, Yoshihisa

    2016-03-01

    A high-magnification image of a biological sample can generally be obtained by an optical microscope with an objective lens, moving the image sensor with a sub-pixel shift and the subsequent image processing for super-resolution. However, to obtain a high-resolution image, a large number of images will be required for the super-resolution, and thus it is difficult to achieve real-time operation, and the field-of-view (FOV) is not sufficiently wide. The currently proposed digital holography technique places a sample on the image sensor and captures the interference fringe (hologram) to reconstruct a 3D high-resolution image in a computer. This technique ensures the features of a wide FOV, whereas the high resolution obtained by image processing cannot ensure real-time operation, because it requires recursive calculations of light propagation and adequate computer resources. To realize wide FOV and the real-time operation at the same time, we have developed a new technique: Lensfree on-chip high-resolution imaging using two-way lighting. High-resolution image is immediately obtained by image processing of the low-resolution images of the samples. This makes it possible to ensure a wide FOV, a deep depth of focus without the need for focus adjustment, and a continuously expanding operation. We also discuss the limitations of the high resolution.

  5. Position Resolution in DROIDs

    NASA Astrophysics Data System (ADS)

    Samedov, Victor V.

    2008-04-01

    Since the very beginning, Distributed Read-Out Imaging Devices (DROIDs) were proposed to achieve both good position and energy resolutions. In DROIDs, the absorption of primary particle energy occurs in a long superconductive strip. Quasiparticles produced in the absorber diffuse along the strip and counted by the superconductive tunnel junctions positioned at the two ends of the strip. In this paper the formula for estimation DROID’s position resolution from experimental data was derived. This formula takes into account correlation between fluctuations of signals of DROID’s detectors.

  6. Graded Achievement, Tested Achievement, and Validity

    ERIC Educational Resources Information Center

    Brookhart, Susan M.

    2015-01-01

    Twenty-eight studies of grades, over a century, were reviewed using the argument-based approach to validity suggested by Kane as a theoretical framework. The review draws conclusions about the meaning of graded achievement, its relation to tested achievement, and changes in the construct of graded achievement over time. "Graded…

  7. Medium-depth chemical peels.

    PubMed

    Monheit, G D

    2001-07-01

    The combination medium-depth chemical peel (Jessner's solution +35% TCA) has been accepted as a safe, reliable, and effective method for the treatment of moderate photoaging skin. This article discusses the procedure in detail, including postoperative considerations. PMID:11599398

  8. Teaching Depth of Field Concept

    ERIC Educational Resources Information Center

    Ross, Frederick C.; Smith, Rodney J.

    1978-01-01

    This activity utilizes an overhead projector, a wax pencil, and a petri-dish to demonstrate the depth of field concept to students learning the use of the microscope. Illustrations and directions are included. (MA)

  9. Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging

    NASA Astrophysics Data System (ADS)

    Micó, Vicente; Zalevsky, Zeev

    2010-07-01

    Digital in-line holographic microscopy (DIHM) is a modern approach capable of achieving micron-range lateral and depth resolutions in three-dimensional imaging. DIHM in combination with numerical imaging reconstruction uses an extremely simplified setup while retaining the advantages provided by holography with enhanced capabilities derived from algorithmic digital processing. We introduce superresolved DIHM incoming from time and angular multiplexing of the sample spatial frequency information and yielding in the generation of a synthetic aperture (SA). The SA expands the cutoff frequency of the imaging system, allowing submicron resolutions in both transversal and axial directions. The proposed approach can be applied when imaging essentially transparent (low-concentration dilutions) and static (slow dynamics) samples. Validation of the method for both a synthetic object (U.S. Air Force resolution test) to quantify the resolution improvement and a biological specimen (sperm cells biosample) are reported showing the generation of high synthetic numerical aperture values working without lenses.

  10. Read-only memory disk with AgOx super-resolution mask layer

    NASA Astrophysics Data System (ADS)

    Zhang, Feng; Wang, Yang; Xu, Wendong; Shi, Hongren; Gan, Fuxi

    2005-02-01

    A novel read-only memory (ROM) disk with an AgOx mask layer was proposed and studied in this letter. The AgOx films sputtered on the premastered substrates, with pits depth of 50 nm and pits length of 380 nm, were studied by an atomic force microscopy. The transmittances of these AgOx films were also measured by a spectrophotometer. Disk measurement was carried out by a dynamic setup with a laser wavelength of 632.8 nm and a lens numerical aperture (NA) of 0.40. The readout resolution limit of this setup was ?/(4NA) (400 nm). Results showed that the super-resolution readout happened only when the oxygen flow ratios were at suitable values for these disks. The best super-resolution performance was achieved at the oxygen flow ratio of 0.5 with the smoothest film surface. The super-resolution readout mechanism of these ROM disks was analyzed as well.

  11. Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry.

    PubMed

    Choi, Heejin; Wadduwage, Dushan; Matsudaira, Paul T; So, Peter T C

    2014-10-01

    A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging both in the spatial and the spectral domain. Images acquired through a standard imaging Fourier transform spectrometer do not have the depth-resolution. By post processing the spectral cubes (x, y, λ) obtained through a Sagnac interferometer under uniform illumination and structured illumination, spectrally resolved images with depth resolution can be recovered using structured light illumination algorithms such as the HiLo method. The proposed scheme is validated with in vitro specimens including fluorescent solution and fluorescent beads with known spectra. The system is further demonstrated in quantifying spectra from 3D resolved features in biological specimens. The system has demonstrated depth resolution of 1.8 μm and spectral resolution of 7 nm respectively.

  12. High Spatio-Temporal Resolution Bathymetry Estimation and Morphology

    NASA Astrophysics Data System (ADS)

    Bergsma, E. W. J.; Conley, D. C.; Davidson, M. A.; O'Hare, T. J.

    2015-12-01

    In recent years, bathymetry estimates using video images have become increasingly accurate. With the cBathy code (Holman et al., 2013) fully operational, bathymetry results with 0.5 metres accuracy have been regularly obtained at Duck, USA. cBathy is based on observations of the dominant frequencies and wavelengths of surface wave motions and estimates the depth (and hence allows inference of bathymetry profiles) based on linear wave theory. Despite the good performance at Duck, large discrepancies were found related to tidal elevation and camera height (Bergsma et al., 2014) and on the camera boundaries. A tide dependent floating pixel and camera boundary solution have been proposed to overcome these issues (Bergsma et al., under review). The video-data collection is set estimate depths hourly on a grid with resolution in the order of 10x25 meters. Here, the application of the cBathy at Porthtowan in the South-West of England is presented. Hourly depth estimates are combined and analysed over a period of 1.5 years (2013-2014). In this work the focus is on the sub-tidal region, where the best cBathy results are achieved. The morphology of the sub-tidal bar is tracked with high spatio-temporal resolution on short and longer time scales. Furthermore, the impact of the storm and reset (sudden and large changes in bathymetry) of the sub-tidal area is clearly captured with the depth estimations. This application shows that the high spatio-temporal resolution of cBathy makes it a powerful tool for coastal research and coastal zone management.

  13. Depth perception of illusory surfaces.

    PubMed

    Kogo, Naoki; Drożdżewska, Anna; Zaenen, Peter; Alp, Nihan; Wagemans, Johan

    2014-03-01

    The perception of an illusory surface, a subjectively perceived surface that is not given in the image, is one of the most intriguing phenomena in vision. It strongly influences the perception of some fundamental properties, namely, depth, lightness and contours. Recently, we suggested (1) that the context-sensitive mechanism of depth computation plays a key role in creating the illusion, (2) that the illusory lightness perception can be explained by an influence of depth perception on the lightness computation, and (3) that the perception of variations of the Kanizsa figure can be well-reproduced by implementing these principles in a model (Kogo, Strecha, et al., 2010). However, depth perception, lightness perception, contour perception, and their interactions can be influenced by various factors. It is essential to measure the differences between the variation figures in these aspects separately to further understand the mechanisms. As a first step, we report here the results of a new experimental paradigm to compare the depth perception of the Kanizsa figure and its variations. One of the illusory figures was presented side-by-side with a non-illusory variation whose stereo disparities were varied. Participants had to decide in which of these two figures the central region appeared closer. The results indicate that the depth perception of the illusory surface was indeed different in the variation figures. Furthermore, there was a non-linear interaction between the occlusion cues and stereo disparity cues. Implications of the results for the neuro-computational mechanisms are discussed.

  14. Focal depth measurement of scanning helium ion microscope

    SciTech Connect

    Guo, Hongxuan; Itoh, Hiroshi; Wang, Chunmei; Zhang, Han; Fujita, Daisuke

    2014-07-14

    When facing the challenges of critical dimension measurement of complicated nanostructures, such as of the three dimension integrated circuit, characterization of the focal depth of microscopes is important. In this Letter, we developed a method for characterizing the focal depth of a scanning helium ion microscope (HIM) by using an atomic force microscope tip characterizer (ATC). The ATC was tilted in a sample chamber at an angle to the scanning plan. Secondary electron images (SEIs) were obtained at different positions of the ATC. The edge resolution of the SEIs shows the nominal diameters of the helium ion beam at different focal levels. With this method, the nominal shapes of the helium ion beams were obtained with different apertures. Our results show that a small aperture is necessary to get a high spatial resolution and high depth of field images with HIM. This work provides a method for characterizing and improving the performance of HIM.

  15. Temporal consistent depth map upscaling for 3DTV

    NASA Astrophysics Data System (ADS)

    Schwarz, Sebastian; Sjöström, Mârten; Olsson, Roger

    2014-03-01

    The ongoing success of three-dimensional (3D) cinema fuels increasing efforts to spread the commercial success of 3D to new markets. The possibilities of a convincing 3D experience at home, such as three-dimensional television (3DTV), has generated a great deal of interest within the research and standardization community. A central issue for 3DTV is the creation and representation of 3D content. Acquiring scene depth information is a fundamental task in computer vision, yet complex and error-prone. Dedicated range sensors, such as the Time­ of-Flight camera (ToF), can simplify the scene depth capture process and overcome shortcomings of traditional solutions, such as active or passive stereo analysis. Admittedly, currently available ToF sensors deliver only a limited spatial resolution. However, sophisticated depth upscaling approaches use texture information to match depth and video resolution. At Electronic Imaging 2012 we proposed an upscaling routine based on error energy minimization, weighted with edge information from an accompanying video source. In this article we develop our algorithm further. By adding temporal consistency constraints to the upscaling process, we reduce disturbing depth jumps and flickering artifacts in the final 3DTV content. Temporal consistency in depth maps enhances the 3D experience, leading to a wider acceptance of 3D media content. More content in better quality can boost the commercial success of 3DTV.

  16. Human machine interface by using stereo-based depth extraction

    NASA Astrophysics Data System (ADS)

    Liao, Chao-Kang; Wu, Chi-Hao; Lin, Hsueh-Yi; Chang, Ting-Ting; Lin, Tung-Yang; Huang, Po-Kuan

    2014-03-01

    The ongoing success of three-dimensional (3D) cinema fuels increasing efforts to spread the commercial success of 3D to new markets. The possibilities of a convincing 3D experience at home, such as three-dimensional television (3DTV), has generated a great deal of interest within the research and standardization community. A central issue for 3DTV is the creation and representation of 3D content. Acquiring scene depth information is a fundamental task in computer vision, yet complex and error-prone. Dedicated range sensors, such as the Time­ of-Flight camera (ToF), can simplify the scene depth capture process and overcome shortcomings of traditional solutions, such as active or passive stereo analysis. Admittedly, currently available ToF sensors deliver only a limited spatial resolution. However, sophisticated depth upscaling approaches use texture information to match depth and video resolution. At Electronic Imaging 2012 we proposed an upscaling routine based on error energy minimization, weighted with edge information from an accompanying video source. In this article we develop our algorithm further. By adding temporal consistency constraints to the upscaling process, we reduce disturbing depth jumps and flickering artifacts in the final 3DTV content. Temporal consistency in depth maps enhances the 3D experience, leading to a wider acceptance of 3D media content. More content in better quality can boost the commercial success of 3DTV.

  17. Histology validation of mapping depth-resolved cardiac fiber orientation in fresh mouse heart using optical polarization tractography

    PubMed Central

    Wang, Y.; Zhang, K.; Wasala, N. B.; Yao, X.; Duan, D.; Yao, G.

    2014-01-01

    Myofiber organization in cardiac muscle plays an important role in achieving normal mechanical and electrical heart functions. An imaging tool that can reveal microstructural details of myofiber organization is valuable for both basic research and clinical applications. A high-resolution optical polarization tractography (OPT) was recently developed based on Jones matrix optical coherence tomography (JMOCT). In this study, we validated the accuracy of using OPT for measuring depth-resolved fiber orientation in fresh heart samples by comparing directly with histology images. Systematic image processing algorithms were developed to register OPT with histology images. The pixel-wise differences between the two tractographic results were analyzed in details. The results indicate that OPT can accurately image depth-resolved fiber orientation in fresh heart tissues and reveal microstructural details at the histological level. PMID:25136507

  18. Noncontact depth-resolved micro-scale optical coherence elastography of the cornea

    PubMed Central

    Wang, Shang; Larin, Kirill V.

    2014-01-01

    High-resolution elastographic assessment of the cornea can greatly assist clinical diagnosis and treatment of various ocular diseases. Here, we report on the first noncontact depth-resolved micro-scale optical coherence elastography of the cornea achieved using shear wave imaging optical coherence tomography (SWI-OCT) combined with the spectral analysis of the corneal Lamb wave propagation. This imaging method relies on a focused air-puff device to load the cornea with highly-localized low-pressure short-duration air stream and applies phase-resolved OCT detection to capture the low-amplitude deformation with nano-scale sensitivity. The SWI-OCT system is used here to image the corneal Lamb wave propagation with the frame rate the same as the OCT A-line acquisition speed. Based on the spectral analysis of the corneal temporal deformation profiles, the phase velocity of the Lamb wave is obtained at different depths for the major frequency components, which shows the depthwise distribution of the corneal stiffness related to its structural features. Our pilot experiments on ex vivo rabbit eyes demonstrate the feasibility of this method in depth-resolved micro-scale elastography of the cornea. The assessment of the Lamb wave dispersion is also presented, suggesting the potential for the quantitative measurement of corneal viscoelasticity. PMID:25426312

  19. Ultra-high resolution Fourier domain optical coherence tomography for old master paintings.

    PubMed

    Cheung, C S; Spring, M; Liang, H

    2015-04-20

    In the last 10 years, Optical Coherence Tomography (OCT) has been successfully applied to art conservation, history and archaeology. OCT has the potential to become a routine non-invasive tool in museums allowing cross-section imaging anywhere on an intact object where there are no other methods of obtaining subsurface information. While current commercial OCTs have shown potential in this field, they are still limited in depth resolution (> 4 μm in paint and varnish) compared to conventional microscopic examination of sampled paint cross-sections (~1 μm). An ultra-high resolution fiber-based Fourier domain optical coherence tomography system with a constant axial resolution of 1.2 μm in varnish or paint throughout a depth range of 1.5 mm has been developed. While Fourier domain OCT of similar resolution has been demonstrated recently, the sensitivity roll-off of some of these systems are still significant. In contrast, this current system achieved a sensitivity roll-off that is less than 2 dB over a 1.2 mm depth range with an incident power of ~1 mW on the sample. The high resolution and sensitivity of the system makes it convenient to image thin varnish and glaze layers with unprecedented contrast. The non-invasive 'virtual' cross-section images obtained with the system show the thin varnish layers with similar resolution in the depth direction but superior clarity in the layer interfaces when compared with conventional optical microscope images of actual paint sample cross-sections obtained micro-destructively. PMID:25969057

  20. Resolution in Photovoltaic Potential Computation

    NASA Astrophysics Data System (ADS)

    Alam, N.; Coors, V.; Zlatanova, S.; Oosterom, P. J. M.

    2016-09-01

    In this paper, an analysis of the effect of the various types of resolution involved in photovoltaic potential computation is presented. To calculate solar energy incident on a surface, shadow from surrounding buildings has been considered. The incident energy on a surface has been calculated taking the orientation, tilt and position into consideration. Different sky visibility map has been created for direct and diffuse radiation and only the effect of resolution of the factors has been explored here. The following four resolutions are considered: 1. temporal resolution (1, 10, 60 minutes time interval for calculating visibility of sun), 2. object surface resolution (0.01, 0.1, 0.375, 0.75, 1.25, 2.5 and 5 m2 as maximum triangle size of a surface to be considered), 3. blocking obstacle resolution (number of triangles from LoD1, LoD2, or LoD3 CityGML building models), and 4. sky resolution (ranging from 150 to 600 sky-patches used to divide the sky-dome). Higher resolutions result in general in more precise estimation of the photovoltaic potential, but also the computation time is increasing, especially as realizes that this computation has to be done for every building with its object surface (both roofs and façades). This paper is the first in depth analysis ever of the effect of resolution and will help to configure the proper settings for effective photovoltaic potential computations.

  1. Conflict resolution.

    PubMed

    Levin, Roger

    2006-03-01

    The sooner conflict is identified and confronted, the more quickly it can be resolved (and the sooner, the better). When this is accomplished calmly and objectively, many areas of conflict will be eliminated. Addressing conflict as it arises also sends a clear message to the team that the practice seeks resolution, not punishment or negative consequences. In addition, the dentist and the office manager need to lead by example by avoiding gossip and encouraging open communication. The goal is to go from a parent-child relationship with the dental team to an adult-adult relationship using this series of managerial conflict resolution steps.

  2. Confocal volume in laser Raman microscopy depth profiling

    SciTech Connect

    Maruyama, Yutaka; Kanematsu, Wataru

    2011-11-15

    To clarify the degradation of confocality in laser Raman microscopy depth profiling (optical sectioning) and the influence of pinhole filtering on it, we investigate the confocal volume in detail based on Gaussian beam optics and scalar wave optics. Theoretical depth profiles of a homogeneous transparent sample for four different pinhole sizes, which are computed using the measured incident beam waist radius w{sub 0} and only a few optical system specific parameters such as a numerical aperture (NA) and a focal length, show a good agreement with the corresponding measured depth profiles. The computed confocal volume demonstrates that the pinhole size affects the actual probe depth as well as the axial resolution and the total intensity loss.

  3. High-resolution extended source optical coherence tomography.

    PubMed

    Yu, Xiaojun; Liu, Xinyu; Chen, Si; Luo, Yuemei; Wang, Xianghong; Liu, Linbo

    2015-10-01

    High resolution optical coherence tomography (OCT) is capable of providing detailed tissue microstructures that are critical for disease diagnosis, yet its sensitivity is usually degraded since the system key components are typically not working at their respective center wavelengths. We developed a novel imaging system that achieves enhanced sensitivity without axial resolution degradation by the use of a spectrally encoded extended source (SEES) technique; it allows larger sample power without exceeding the maximum permissible exposure (MPE). In this study, we demonstrate a high-resolution extended source (HRES) OCT system, which is capable of providing a transverse resolution of 4.4 µm and an axial resolution of 2.1 µm in air with the SEES technique. We first theoretically show a sensitivity advantage of 6-dB of the HRES-OCT over that of its point source counterpart using numerical simulations, and then experimentally validate the applicability of the SEES technique to high-resolution OCT (HR-OCT) by comparing the HRES-OCT with an equivalent point-source system. In the HRES-OCT system, a dispersive prism was placed in the infinity space of the sample arm optics to spectrally extend the visual angle (angular subtense) of the light source to 10.3 mrad. This extended source allowed ~4 times larger MPE than its point source counterpart, which results in an enhancement of ~6 dB in sensitivity. Specifically, to solve the unbalanced dispersion between the sample and the reference arm optics, we proposed easy and efficient methods for system calibration and dispersion correction, respectively. With a maximum scanning speed reaching up to 60K A-lines/s, we further conducted imaging experiments with HRES-OCT using the human fingertip in vivo and the swine eye tissues ex vivo. Results demonstrate that the HRES-OCT is able to achieve significantly larger penetration depth than its conventional point source OCT counterpart.

  4. Composite hull for full-ocean depth

    SciTech Connect

    Garvey, R.E.; Hawkes, G.S.

    1990-01-01

    A lightweight and economical modular design concept for a manned submersible is proposed to give two passengers repeated access to the deepest parts of the ocean in a safe, comfortable, and efficient manner. This versatile craft will allow work and exploration to be accomplished at moderate to maximum depths without any compromise in terms of capabilities or operating cost. Its design follows the experience acquired from the numerous existing minimum volume'' pressure hull submersible, and represents a radical departure from conventional designs. This paper addresses issues of gaining effective, safe working access for full ocean depth. Cylindrical composite hulls have the potential to achieve positive buoyancy sufficient to carry personnel and equipment swiftly back to the surface after completing exploration of the deepest ocean. Buoyancy for a submersible is similar to lift for an airplane, except that without lift, the airplane remains on the surface, but without buoyancy, the submersible never returns to the surface. There are two means of achieving buoyancy. The traditional method used to steel, titanium, or aluminium alloy deep-ocean vehicles is to add a very large buoy to compensate for the negative buoyancy of the hull. The alternate method is for the hull to displace more than its weight in water. This requires at least twice compression strength per unit mass of hull than steel, titanium, or aluminum alloys can provide. Properly constructed organic-matrix composites are light and strong enough to form a dry, 1-atm cabin with buoyancy to carry research staff and equipment to any depth in the ocean. Three different composite hull configurations are presented. Each is capable of serving as a cabin for a two-person crew. None would displace more than 4 tons of seawater. 30 refs., 3 figs., 1 tab.

  5. Monitoring the Depth of Anaesthesia

    PubMed Central

    Musizza, Bojan; Ribaric, Samo

    2010-01-01

    One of the current challenges in medicine is monitoring the patients’ depth of general anaesthesia (DGA). Accurate assessment of the depth of anaesthesia contributes to tailoring drug administration to the individual patient, thus preventing awareness or excessive anaesthetic depth and improving patients’ outcomes. In the past decade, there has been a significant increase in the number of studies on the development, comparison and validation of commercial devices that estimate the DGA by analyzing electrical activity of the brain (i.e., evoked potentials or brain waves). In this paper we review the most frequently used sensors and mathematical methods for monitoring the DGA, their validation in clinical practice and discuss the central question of whether these approaches can, compared to other conventional methods, reduce the risk of patient awareness during surgical procedures. PMID:22163504

  6. NCAI Resolutions

    ERIC Educational Resources Information Center

    American Indian Journal of the Institute for the Development of Indian Law, 1977

    1977-01-01

    Five Major Policy Resolutions were adopted, without objection, at the 33rd Annual Convention of the National Congress of American Indians (NCAI) held in Salt Lake City, Utah, in October 1976. The issues involved were: Treaties and Trust Responsibilities, Tribal Government, Jurisdiction, Federal Administration and Structure of Indian Affairs, and…

  7. Flexible depth of field photography.

    PubMed

    Kuthirummal, Sujit; Nagahara, Hajime; Zhou, Changyin; Nayar, Shree K

    2011-01-01

    The range of scene depths that appear focused in an image is known as the depth of field (DOF). Conventional cameras are limited by a fundamental trade-off between depth of field and signal-to-noise ratio (SNR). For a dark scene, the aperture of the lens must be opened up to maintain SNR, which causes the DOF to reduce. Also, today's cameras have DOFs that correspond to a single slab that is perpendicular to the optical axis. In this paper, we present an imaging system that enables one to control the DOF in new and powerful ways. Our approach is to vary the position and/or orientation of the image detector during the integration time of a single photograph. Even when the detector motion is very small (tens of microns), a large range of scene depths (several meters) is captured, both in and out of focus. Our prototype camera uses a micro-actuator to translate the detector along the optical axis during image integration. Using this device, we demonstrate four applications of flexible DOF. First, we describe extended DOF where a large depth range is captured with a very wide aperture (low noise) but with nearly depth-independent defocus blur. Deconvolving a captured image with a single blur kernel gives an image with extended DOF and high SNR. Next, we show the capture of images with discontinuous DOFs. For instance, near and far objects can be imaged with sharpness, while objects in between are severely blurred. Third, we show that our camera can capture images with tilted DOFs (Scheimpflug imaging) without tilting the image detector. Finally, we demonstrate how our camera can be used to realize nonplanar DOFs. We believe flexible DOF imaging can open a new creative dimension in photography and lead to new capabilities in scientific imaging, vision, and graphics. PMID:21088319

  8. Sedimentary basins reconnaissance using the magnetic Tilt-Depth method

    NASA Astrophysics Data System (ADS)

    Salem, Ahmed; Williams, Simon; Samson, Esuene; Fairhead, Derek; Ravat, Dhananjay; Blakely, Richard J.

    2010-09-01

    We compute the depth to the top of magnetic basement using the Tilt-Depth method from the best available magnetic anomaly grids covering the continental USA and Australia. For the USA, the Tilt-Depth estimates were compared with sediment thicknesses based on drilling data and show a correlation of 0.86 between the datasets. If random data were used then the correlation value goes to virtually zero. There is little to no lateral offset of the depth of basinal features although there is a tendency for the Tilt-Depth results to be slightly shallower than the drill depths. We also applied the Tilt-Depth method to a local-scale, relatively high-resolution aeromagnetic survey over the Olympic Peninsula of Washington State. The Tilt-Depth method successfully identified a variety of important tectonic elements known from geological mapping. Of particular interest, the Tilt-Depth method illuminated deep (3km) contacts within the non-magnetic sedimentary core of the Olympic Mountains, where magnetic anomalies are subdued and low in amplitude. For Australia, the Tilt-Depth estimates also give a good correlation with known areas of shallow basement and sedimentary basins. Our estimates of basement depth are not restricted to regional analysis but work equally well at the micro scale (basin scale) with depth estimates agreeing well with drill hole and seismic data. We focus on the eastern Officer Basin as an example of basin scale studies and find a good level of agreement between previously-derived basin models. However, our study potentially reveals depocentres not previously mapped due to the sparse distribution of well data. This example thus shows the potential additional advantage of the method in geological interpretation. The success of this study suggests that the Tilt-Depth method is useful in estimating the depth to crystalline basement when appropriate quality aeromagnetic anomaly data are used (i.e. line spacing on the order of or less than the expected depth to

  9. Sedimentary basins reconnaissance using the magnetic Tilt-Depth method

    USGS Publications Warehouse

    Salem, A.; Williams, S.; Samson, E.; Fairhead, D.; Ravat, D.; Blakely, R.J.

    2010-01-01

    We compute the depth to the top of magnetic basement using the Tilt-Depth method from the best available magnetic anomaly grids covering the continental USA and Australia. For the USA, the Tilt-Depth estimates were compared with sediment thicknesses based on drilling data and show a correlation of 0.86 between the datasets. If random data were used then the correlation value goes to virtually zero. There is little to no lateral offset of the depth of basinal features although there is a tendency for the Tilt-Depth results to be slightly shallower than the drill depths. We also applied the Tilt-Depth method to a local-scale, relatively high-resolution aeromagnetic survey over the Olympic Peninsula of Washington State. The Tilt-Depth method successfully identified a variety of important tectonic elements known from geological mapping. Of particular interest, the Tilt-Depth method illuminated deep (3km) contacts within the non-magnetic sedimentary core of the Olympic Mountains, where magnetic anomalies are subdued and low in amplitude. For Australia, the Tilt-Depth estimates also give a good correlation with known areas of shallow basement and sedimentary basins. Our estimates of basement depth are not restricted to regional analysis but work equally well at the micro scale (basin scale) with depth estimates agreeing well with drill hole and seismic data. We focus on the eastern Officer Basin as an example of basin scale studies and find a good level of agreement between previously-derived basin models. However, our study potentially reveals depocentres not previously mapped due to the sparse distribution of well data. This example thus shows the potential additional advantage of the method in geological interpretation. The success of this study suggests that the Tilt-Depth method is useful in estimating the depth to crystalline basement when appropriate quality aeromagnetic anomaly data are used (i.e. line spacing on the order of or less than the expected depth to

  10. Theoretical Framework for the Assessment of Uncertainties in Snow Depth Measurements

    NASA Astrophysics Data System (ADS)

    Trujillo, E.; Lehning, M.

    2014-12-01

    In recent years, marked improvements in our knowledge of the statistical properties of the spatial distribution of snow properties have been achieved thanks to improvements in measuring technologies (e.g., LIDAR, TLS, and GPR). Despite of this, objective and quantitative frameworks for the evaluation of uncertainties in snow measurements have been lacking. Here, we present a theoretical framework for quantitative evaluations of the uncertainty of point measurements of snow depth when used to represent the average depth over a profile section or an area. We define the error as the expected value of the squared difference between the real mean of the profile/field and the sample mean from a limited number of measurements. The model is tested for one and two dimensional survey designs that range from a single measurement to an increasing number of regularly-spaced measurements. Using high-resolution (~ 1m) LIDAR snow depths at three locations in Colorado, we show that the sample errors follow the theoretical behavior. Furthermore, we show how the determination of the spatial location of the measurements can be reduced to an optimization problem for the case of a predefined number of measurements, or to the designation of an acceptable uncertainty level to determine the total number of regularly-spaced measurements required to achieve such error. On this basis, a series of figures are presented that can be used to aid in the determination of the survey design under the conditions described, and under the assumption of prior knowledge of the spatial covariance/correlation properties. With this methodology, better objective survey designs can be accomplished, tailored to the specific applications for which the measurements are going to be used. Although we discuss the proposed methodology in the context of snow depth, the theoretical framework can be extended to other spatially distributed snow variables (e.g., SWE and/or snow depth) or hydrologic variables (e.g., soil

  11. 3D astigmatic depth sensing camera

    NASA Astrophysics Data System (ADS)

    Birch, Gabriel C.; Tyo, J. Scott; Schwiegerling, Jim

    2011-10-01

    Three-dimensional displays have become increasingly present in consumer markets. However, the ability to capture threedimensional images inexpensively and without major modifications to current cameras is uncommon. Our goal is to create a modification to a common commercial camera that allows a three dimensional reconstruction. We desire such an imaging system to be inexpensive and easy to use. Furthermore, we require that any three-dimensional modification to a camera does not reduce its resolution. Here we present a possible solution to this problem. A commercial digital camera is used with a projector system with astigmatic focus to capture images of a scene. By using an astigmatic projected pattern we can create two different focus depths for horizontal and vertical features of the projected pattern, thereby encoding depth. This projector could be integrated into the flash unit of the camera. By carefully choosing a pattern we are able to exploit this differential focus in image processing. Wavelet transforms are performed on the image that pick out the projected pattern. By taking ratios of certain wavelet coefficients we are able to correlate the distance an object at a particular transverse position is from the camera to the contrast ratios. We present our information regarding construction, calibration, and images produced by this system. The nature of linking a projected pattern design and image processing algorithms will be discussed.

  12. In vivo photoacoustic flowmetry at depths of the diffusive regime based on saline injection

    PubMed Central

    Zhou, Yong; Poudel, Joemini; Li, Guo; Wang, Lihong V.

    2015-01-01

    Abstract. We propose a saline injection-based method to quantify blood flow velocity in vivo with acoustic-resolution photoacoustic tomography. By monitoring the saline–blood interface propagating in the blood vessel, the flow velocity can be resolved. We first demonstrated our method in phantom experiments, where a root mean square error of prediction of 0.29  mm/s was achieved. By injecting saline into a mouse tail vein covered with 1 mm chicken tissue, we showed that the flow velocity in the tail vein could be measured at depths, which is especially pertinent to monitoring blood flow velocity in patients undergoing intravenous infusion. PMID:26267364

  13. Ultra-slim 2D- and depth-imaging camera modules for mobile imaging

    NASA Astrophysics Data System (ADS)

    Brückner, Andreas; Oberdörster, Alexander; Dunkel, Jens; Reimann, Andreas; Wippermann, Frank

    2016-03-01

    In this contribution, a microoptical imaging system is demonstrated that is inspired by the insect compound eye. The array camera module achieves HD resolution with a z-height of 2.0 mm, which is about 50% compared to traditional cameras with comparable parameters. The FOV is segmented by multiple optical channels imaging in parallel. The partial images are stitched together to form a final image of the whole FOV by image processing software. The system is able to acquire depth maps along with the 2D video and it includes light field imaging features such as software refocusing. The microlens arrays are realized by microoptical technologies on wafer-level which are suitable for a potential fabrication in high volume.

  14. Mobility and low contrast trip hazard avoidance using augmented depth

    NASA Astrophysics Data System (ADS)

    McCarthy, Chris; Walker, Janine G.; Lieby, Paulette; Scott, Adele; Barnes, Nick

    2015-02-01

    Objective. We evaluated a novel visual representation for current and near-term prosthetic vision. Augmented depth emphasizes ground obstacles and floor-wall boundaries in a depth-based visual representation. This is achieved by artificially increasing contrast between obstacles and the ground surface via a novel ground plane extraction algorithm specifically designed to preserve low-contrast ground-surface boundaries. Approach. The effectiveness of augmented depth was examined in human mobility trials compared against standard intensity-based (Intensity), depth-based (Depth) and random (Random) visual representations. Eight participants with normal vision used simulated prosthetic vision with 20 phosphenes and eight perceivable brightness levels to traverse a course with randomly placed small and low-contrast obstacles on the ground. Main results. The number of collisions was significantly reduced using augmented depth, compared with intensity, depth and random representations (48%, 44% and 72% less collisions, respectively). Significance. These results indicate that augmented depth may enable safe mobility in the presence of low-contrast obstacles with current and near-term implants. This is the first demonstration that an augmentation of the scene ensuring key objects are visible may provide better outcomes for prosthetic vision.

  15. Fast mode decision for 3D-HEVC depth intracoding.

    PubMed

    Zhang, Qiuwen; Li, Nana; Wu, Qinggang

    2014-01-01

    The emerging international standard of high efficiency video coding based 3D video coding (3D-HEVC) is a successor to multiview video coding (MVC). In 3D-HEVC depth intracoding, depth modeling mode (DMM) and high efficiency video coding (HEVC) intraprediction mode are both employed to select the best coding mode for each coding unit (CU). This technique achieves the highest possible coding efficiency, but it results in extremely large encoding time which obstructs the 3D-HEVC from practical application. In this paper, a fast mode decision algorithm based on the correlation between texture video and depth map is proposed to reduce 3D-HEVC depth intracoding computational complexity. Since the texture video and its associated depth map represent the same scene, there is a high correlation among the prediction mode from texture video and depth map. Therefore, we can skip some specific depth intraprediction modes rarely used in related texture CU. Experimental results show that the proposed algorithm can significantly reduce computational complexity of 3D-HEVC depth intracoding while maintaining coding efficiency. PMID:24963512

  16. Depth dependent multiple logging system

    SciTech Connect

    Howells, A. P. S.; Angehrn, J. A.; Dienglewicz, A. M.; Viswanathan, R.

    1985-12-03

    An improved well logging technique is provided for more accurately deriving and correlating a plurality of measurements made during a single traversal of a logging instrument through subsurface formations. In one exemplary embodiment, methods and apparatus are provided for deriving a more accurate and precise measurement of depth at which real-time logging measurements are made, and in particular for correcting anomalies occurring in the depth indication from cable stretch, yo-yo of the sonde in the borehole and the like. The more accurate and precise depth measurement is then utilized for generating well logging measurements on a depth-dependent basis, deriving at least some of such measurements in digital form and alternately transmitting to the surface digital and analog representations of such measurements. Furthermore, methods and apparatus are provided for deriving measurements of subsurface earth formation from a plurality of logging instruments combined in a single tool, wherein such measurements are made during a single pass through a borehole with the resultant measurement data correlatively merged, recorded and displayed.

  17. Rotating drum variable depth sampler

    SciTech Connect

    Nance, Thomas A.; Steeper, Timothy J.

    2008-07-01

    A sampling device for collecting depth-specific samples in silt, sludge and granular media has three chambers separated by a pair of iris valves. Rotation of the middle chamber closes the valves and isolates a sample in a middle chamber.

  18. Perceived depth from shading boundaries.

    PubMed

    Kim, Juno; Anstis, Stuart

    2016-01-01

    Shading is well known to provide information the visual system uses to recover the three-dimensional shape of objects. We examined conditions under which patterns in shading promote the experience of a change in depth at contour boundaries, rather than a change in reflectance. In Experiment 1, we used image manipulation to illuminate different regions of a smooth surface from different directions. This manipulation imposed local differences in shading direction across edge contours (delta shading). We found that increasing the angle of delta shading, from 0° to 180°, monotonically increased perceived depth across the edge. Experiment 2 found that the perceptual splitting of shading into separate foreground and background surfaces depended on an assumed light source from above prior. Image regions perceived as foreground structures in upright images appeared farther in depth when the same images were inverted. We also found that the experienced break in surface continuity could promote the experience of amodal completion of colored contours that were ambiguous as to their depth order (Experiment 3). These findings suggest that the visual system can identify occlusion relationships based on monocular variations in local shading direction, but interprets this information according to a light source from above prior of midlevel visual processing.

  19. Pursuing the Depths of Knowledge

    ERIC Educational Resources Information Center

    Boyles, Nancy

    2016-01-01

    Today's state literacy standards and assessments demand deeper levels of knowledge from students. But many teachers ask, "What does depth of knowledge look like on these new, more rigorous assessments? How do we prepare students for this kind of thinking?" In this article, Nancy Boyles uses a sampling of questions from the PARCC and SBAC…

  20. Perceived depth from shading boundaries.

    PubMed

    Kim, Juno; Anstis, Stuart

    2016-01-01

    Shading is well known to provide information the visual system uses to recover the three-dimensional shape of objects. We examined conditions under which patterns in shading promote the experience of a change in depth at contour boundaries, rather than a change in reflectance. In Experiment 1, we used image manipulation to illuminate different regions of a smooth surface from different directions. This manipulation imposed local differences in shading direction across edge contours (delta shading). We found that increasing the angle of delta shading, from 0° to 180°, monotonically increased perceived depth across the edge. Experiment 2 found that the perceptual splitting of shading into separate foreground and background surfaces depended on an assumed light source from above prior. Image regions perceived as foreground structures in upright images appeared farther in depth when the same images were inverted. We also found that the experienced break in surface continuity could promote the experience of amodal completion of colored contours that were ambiguous as to their depth order (Experiment 3). These findings suggest that the visual system can identify occlusion relationships based on monocular variations in local shading direction, but interprets this information according to a light source from above prior of midlevel visual processing. PMID:27271807

  1. 21 CFR 314.103 - Dispute resolution.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Dispute resolution. 314.103 Section 314.103 Food... Applications § 314.103 Dispute resolution. (a) General. FDA is committed to resolving differences between... application. If resolution is not achieved, the applicant may raise the matter with the person designated...

  2. Shallow depth subsurface imaging with microwave holography

    NASA Astrophysics Data System (ADS)

    Zhuravlev, Andrei; Ivashov, Sergey; Razevig, Vladimir; Vasiliev, Igor; Bechtel, Timothy

    2014-05-01

    In this paper, microwave holography is considered as a tool to obtain high resolution images of shallowly buried objects. Signal acquisition is performed at multiple frequencies on a grid using a two-dimensional mechanical scanner moving a single transceiver over an area of interest in close proximity to the surface. The described FFT-based reconstruction technique is used to obtain a stack of plan view images each using only one selected frequency from the operating waveband of the radar. The extent of a synthetically-formed aperture and the signal wavelength define the plan view resolution, which at sounding frequencies near 7 GHz amounts to 2 cm. The system has a short depth of focus which allows easy selection of proper focusing plane. The small distance from the buried objects to the antenna does not prevent recording of clean images due to multiple reflections (as happens with impulse radars). The description of the system hardware and signal processing technique is illustrated using experiments conducted in dry sand. The microwave images of inert anti-personnel mines are demonstrated as examples. The images allow target discrimination based on the same visually-discernible small features that a human observer would employ. The demonstrated technology shows promise for modification to meet the specific practical needs required for humanitarian demining or in multi-sensor survey systems.

  3. A resolution honoring the lifetime achievements of E. Thom Rumberger.

    THOMAS, 112th Congress

    Sen. Nelson, Bill [D-FL

    2011-09-13

    09/13/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S5584-5585; text as passed Senate: CR S5585; text of measure as introduced: CR S5583) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  4. A resolution honoring the achievements of E. Thom Rumberger.

    THOMAS, 112th Congress

    Sen. Nelson, Bill [D-FL

    2011-08-01

    08/01/2011 Read twice and referred to the Committee on the Judiciary. (text of measure as introduced: CR S5196) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. Depth Sectioning with the Aberration-Corrected Scanning Transmission Electron Microscope

    SciTech Connect

    Borisevich, Albina Y; Lupini, Andrew R; Pennycook, Stephen J

    2006-01-01

    The ability to correct the aberrations of the probe-forming lens in the scanning transmission electron microscope provides not only a significant improvement in transverse resolution but in addition brings depth resolution at the nanometer scale. Aberration correction therefore opens up the possibility of 3D imaging by optical sectioning. Here we develop a definition for the depth resolution for scanning transmission electron microscope depth sectioning and present initial results from this method. Objects such as catalytic metal clusters and single atoms on various support materials are imaged in three dimensions with a resolution of several nanometers. Effective focal depth is determined by statistical analysis and the contributing factors are discussed. Finally, current challenges and future capabilities available through new instruments are discussed.

  6. Depth-resolved monitoring of analytes diffusion in ocular tissues

    NASA Astrophysics Data System (ADS)

    Larin, Kirill V.; Ghosn, Mohamad G.; Tuchin, Valery V.

    2007-02-01

    Optical coherence tomography (OCT) is a noninvasive imaging technique with high in-depth resolution. We employed OCT technique for monitoring and quantification of analyte and drug diffusion in cornea and sclera of rabbit eyes in vitro. Different analytes and drugs such as metronidazole, dexamethasone, ciprofloxacin, mannitol, and glucose solution were studied and whose permeability coefficients were calculated. Drug diffusion monitoring was performed as a function of time and as a function of depth. Obtained results suggest that OCT technique might be used for analyte diffusion studies in connective and epithelial tissues.

  7. Development of Extended-Depth Swept Source Optical Coherence Tomography for Applications in Ophthalmic Imaging of the Anterior and Posterior Eye

    NASA Astrophysics Data System (ADS)

    Dhalla, Al-Hafeez Zahir

    Optical coherence tomography (OCT) is a non-invasive optical imaging modality that provides micron-scale resolution of tissue micro-structure over depth ranges of several millimeters. This imaging technique has had a profound effect on the field of ophthalmology, wherein it has become the standard of care for the diagnosis of many retinal pathologies. Applications of OCT in the anterior eye, as well as for imaging of coronary arteries and the gastro-intestinal tract, have also shown promise, but have not yet achieved widespread clinical use. The usable imaging depth of OCT systems is most often limited by one of three factors: optical attenuation, inherent imaging range, or depth-of-focus. The first of these, optical attenuation, stems from the limitation that OCT only detects singly-scattered light. Thus, beyond a certain penetration depth into turbid media, essentially all of the incident light will have been multiply scattered, and can no longer be used for OCT imaging. For many applications (especially retinal imaging), optical attenuation is the most restrictive of the three imaging depth limitations. However, for some applications, especially anterior segment, cardiovascular (catheter-based) and GI (endoscopic) imaging, the usable imaging depth is often not limited by optical attenuation, but rather by the inherent imaging depth of the OCT systems. This inherent imaging depth, which is specific to only Fourier Domain OCT, arises due to two factors: sensitivity fall-off and the complex conjugate ambiguity. Finally, due to the trade-off between lateral resolution and axial depth-of-focus inherent in diffractive optical systems, additional depth limitations sometimes arises in either high lateral resolution or extended depth OCT imaging systems. The depth-of-focus limitation is most apparent in applications such as adaptive optics (AO-) OCT imaging of the retina, and extended depth imaging of the ocular anterior segment. In this dissertation, techniques for

  8. Design of an optical system with large depth of field using in the micro-assembly

    NASA Astrophysics Data System (ADS)

    Li, Rong; Chang, Jun; Zhang, Zhi-jing; Ye, Xin; Zheng, Hai-jing

    2013-08-01

    Micro system currently is the mainstream of application and demand of the field of micro fabrication of civilian and national defense. Compared with the macro assembly, the requirements on location accuracy of the micro-assembly system are much higher. Usually the dimensions of the components of the micro-assembly are mostly between a few microns to several hundred microns. The general assembly precision requires for the sub-micron level. Micro system assembly is the bottleneck of micro fabrication currently. The optical stereo microscope used in the field of micro assembly technology can achieve high-resolution imaging, but the depth of field of the optical imaging system is too small. Thus it's not conducive to the three-dimensional observation process of the micro-assembly. This paper summarizes the development of micro system assembly at home and abroad firstly. Based on the study of the core features of the technology, a program is proposed which uses wave front coding technology to increase the depth of field of the optical imaging system. In the wave front coding technology, by combining traditional optical design with digital image processing creatively, the depth of field can be greatly increased, moreover, all defocus-related aberrations, such as spherical aberration, chromatic aberration, astigmatism, Ptzvel(field) curvature, distortion, and other defocus induced by the error of assembling and temperature change, can be corrected or minimized. In this paper, based on the study of theory, a set of optical microscopy imaging system is designed. This system is designed and optimized by optical design software CODE V and ZEMAX. At last, the imaging results of the traditional optical stereo microscope and the optical stereo microscope applied wave front coding technology are compared. The results show that: the method has a practical operability and the phase plate obtained by optimized has a good effect on improving the imaging quality and increasing the

  9. Sputter-depth profiling for thin-film analysis.

    PubMed

    Hofmann, S

    2004-01-15

    Following a brief historical background, the concepts and the present state of sputter-depth profiling for thin-film analysis are outlined. There are two main branches: either the removed matter (as in mass- or optical-spectroscopy-based secondary-ion mass spectrometry or glow-discharge optical emission spectroscopy), or the remaining surface (as in Auger electron spectroscopy and X-ray photoelectron spectroscopy) is characterized. These complementary methods show the same result if there is no preferential sputtering of a component. The common root of both is the fundamental ion-solid interaction. Understanding of how the latter influences the depth resolution has led to important improvements in experimental profiling conditions such as sample rotation and the use of low-energy ions at glancing incidence. Modern surface-analysis instruments can provide high-resolution depth profiles on the nanometre scale. Mathematical models of different sophistication were developed to allow deconvolution of the measured profile or quantification by reconstruction of the in-depth distribution of composition. For the latter purpose, the usefulness of the so-called mixing-roughness-information (MRI) depth model is outlined on several thin-film structures (e.g. AlAs/GaAs and Si/Ge), including its extension to quantification of sputter-depth profiles in layer structures with preferential sputtering of one component (Ta/Si). Using the MRI model, diffusion coefficients at interfaces as low as 10(-22) m(2) s(-1) can be determined. Fundamental limitations of sputter-depth profiling are mainly traced back to the stochastic nature of primary-particle energy transfer to the sputtered particle, promoting atomic mixing and the development of surface roughness. Owing to more sophisticated experimental methods, such as low-energy cluster ion bombardment, glancing ion incidence or 'backside' sputtering, these ultimate limitations can be reduced to the atomic monolayer scale.

  10. Image Resolution in Optical Nanoscopy

    PubMed Central

    Nieuwenhuizen, Robert P.J.; Lidke, Keith A.; Bates, Mark; Puig, Daniela Leyton; Grünwald, David; Stallinga, Sjoerd; Rieger, Bernd

    2014-01-01

    Resolution in optical nanoscopy depends on the localization uncertainty of single fluorescent labels, the density of labels covering the sample, and the sample’s spatial structure. Currently there is no integral, practical resolution measure that takes all factors into account. Here we introduce such a measure that can be computed directly from the image. We demonstrate its validity and benefits on 2D and 3D localization microscopy images of tubulin and actin filaments. Our approach makes it possible to compare achieved resolutions in images taken with different nanoscopy methods, optimize and rank different emitter localization and labeling strategies, define a stopping criterion for data acquisition, describe image anisotropy and heterogeneity, and, surprisingly, estimate the average number of localizations per emitter. Our findings challenge the current focus on obtaining the best localization precision, but instead show how the best image resolution can be achieved as fast as possible. PMID:23624665

  11. Explosion depths for phreatomagmatic eruptions

    NASA Astrophysics Data System (ADS)

    Valentine, Greg A.; Graettinger, Alison H.; Sonder, Ingo

    2014-05-01

    Subsurface phreatomagmatic explosions can result from the interaction of ascending magma with groundwater. Experiments over a wide range of energies show that for a given energy there is a depth below which an explosion will be contained within the subsurface (not erupt), and there is a corresponding shallower depth that will optimize ejecta dispersal. We combine these relationships with constraints on the energies of phreatomagmatic explosions at maar-diatreme volcanoes and show that most eruptions are likely sourced by explosions in the uppermost ~200 m, and even shallower ones (<100 m) are likely to dominate deposition onto tephra rings. Most explosions below ~200 m will not erupt but contribute to formation of, and to the vertical mixing of materials within, a diatreme (vent structure), with only rare very high energy explosions between ~200 and 500 m erupting. Similar constraints likely apply at other volcanoes that experience phreatomagmatic explosions.

  12. Ultrasonic material hardness depth measurement

    DOEpatents

    Good, Morris S.; Schuster, George J.; Skorpik, James R.

    1997-01-01

    The invention is an ultrasonic surface hardness depth measurement apparatus and method permitting rapid determination of hardness depth of shafts, rods, tubes and other cylindrical parts. The apparatus of the invention has a part handler, sensor, ultrasonic electronics component, computer, computer instruction sets, and may include a display screen. The part handler has a vessel filled with a couplant, and a part rotator for rotating a cylindrical metal part with respect to the sensor. The part handler further has a surface follower upon which the sensor is mounted, thereby maintaining a constant distance between the sensor and the exterior surface of the cylindrical metal part. The sensor is mounted so that a front surface of the sensor is within the vessel with couplant between the front surface of the sensor and the part.

  13. Ultrasonic material hardness depth measurement

    DOEpatents

    Good, M.S.; Schuster, G.J.; Skorpik, J.R.

    1997-07-08

    The invention is an ultrasonic surface hardness depth measurement apparatus and method permitting rapid determination of hardness depth of shafts, rods, tubes and other cylindrical parts. The apparatus of the invention has a part handler, sensor, ultrasonic electronics component, computer, computer instruction sets, and may include a display screen. The part handler has a vessel filled with a couplant, and a part rotator for rotating a cylindrical metal part with respect to the sensor. The part handler further has a surface follower upon which the sensor is mounted, thereby maintaining a constant distance between the sensor and the exterior surface of the cylindrical metal part. The sensor is mounted so that a front surface of the sensor is within the vessel with couplant between the front surface of the sensor and the part. 12 figs.

  14. Next Generation Nuclear Plant Defense-in-Depth Approach

    SciTech Connect

    Edward G. Wallace; Karl N. Fleming; Edward M. Burns

    2009-12-01

    The purpose of this paper is to (1) document the definition of defense-in-depth and the pproach that will be used to assure that its principles are satisfied for the NGNP project and (2) identify the specific questions proposed for preapplication discussions with the NRC. Defense-in-depth is a safety philosophy in which multiple lines of defense and conservative design and evaluation methods are applied to assure the safety of the public. The philosophy is also intended to deliver a design that is tolerant to uncertainties in knowledge of plant behavior, component reliability or operator performance that might compromise safety. This paper includes a review of the regulatory foundation for defense-in-depth, a definition of defense-in-depth that is appropriate for advanced reactor designs based on High Temperature Gas-cooled Reactor (HTGR) technology, and an explanation of how this safety philosophy is achieved in the NGNP.

  15. Probabilistically Constraining Age-Depth-Models of Glaciogenic Sediments

    NASA Astrophysics Data System (ADS)

    Werner, J.; van der Bilt, W.; Tingley, M.

    2015-12-01

    Reconstructions of the late-Holocene climate rely heavily upon proxies that are assumed to be accurately dated by layer counting. All of these proxies, such as measurements of tree rings, ice cores, and varved lake sediments do carry some inherent dating uncertainty that is not always fully accounted for. Considerable advances could be achieved if time uncertainties were recognized and correctly modeled, also for proxies commonly treated as free of age model errors. Current approaches for accounting for time uncertainty are generally limited to repeating the reconstruction using each one of an ensemble of age models, thereby inflating the final estimated uncertainty - in effect, each possible age model is given equal weighting. Uncertainties can be reduced by exploiting the inferred space-time covariance structure of the climate to re-weight the possible age models. Werner and Tingley (2015) demonstrated how Bayesian hierarchical climate reconstruction models can be augmented to account for time-uncertain proxies. In their method, probabilities associated with the age models are formally updated within the Bayesian framework, thereby reducing uncertainties. Numerical experiments (Werner and Tingley 2015) show that updating the age model probabilities decreases uncertainty in the resulting reconstructions, as compared with the current de facto standard of sampling over all age models, provided there is sufficient information from other data sources in the spatial region of the time-uncertain proxy. We show how this novel method can be applied to high resolution, sub-annually sampled lacustrine sediment records to constrain their respective age depth models. The results help to quantify the signal content and extract the regionally representative signal. The single time series can then be used as the basis for a reconstruction of glacial activity. van der Bilt et al. in prep. Werner, J.P. and Tingley, M.P. Clim. Past (2015)

  16. High-Resolution UV Relay Lens for Particle Size Distribution Measurements Using Holography

    SciTech Connect

    Robert M. Malone, Brent C. Frogget, Morris I. Kaufman, Aric Tibbits, Gene A. Capelle, Mike Grover, Gerald D. Stevens, William D. Turley

    2008-03-01

    Shock waves passing through a metal sample can produce ejecta particulates at a metal-vacuum interface. Holography records particle size distributions by using a highpower, short-pulse laser to freeze particle motion. The sizes of the ejecta particles are recorded using an in-line Fraunhofer holography technique. Because the holographic plate would be destroyed in this energetic environment, a high-resolution lens has been designed to relay the interference fringes to a safe environment. Particle sizes within a 12-mm-diameter, 5-mm-thick volume are recorded on holographic film. To achieve resolution down to 0.5 microns, ultraviolet (UV) light (in this case supplied by a tripled Nd:YAG laser) is needed. The design and assembly of a nine-element lens that achieves >2000 lp/mm resolution and operates at f/0.85 will be described. To set up this lens system, a doublet lens is temporarily attached that enables operation with 532-nm (green) light and 1100 lp/mm resolution. Thus, the setup and alignment is performed with green light, but the dynamic recording is done with UV light. During setup, the 532-nm beam provides enough focus shift to accommodate the placement of a resolution pattern outside the ejecta volume; this resolution pattern does not interfere with the calibrated wires and pegs surrounding the ejecta volume. A television microscope archives images of resolution patterns that prove that the calibration wires, interference filter, holographic plate, and relay lenses are in their correct positions. Part of this lens is under vacuum, at the point where the laser illumination passes through a focus. Alignment and tolerancing of this high-resolution lens will be presented, and resolution variation through the 5-mm depth of field will be discussed.

  17. High-Resolution UV Relay Lens for Particle Size Distribution Measurements Using Holography

    SciTech Connect

    Malone, Robert M.; Capelle, Gene A.; Frogget, Brent C.; Grover, Mike; Kaufman, Morris I.; Pazuchanics, Peter; Sorenson, Danny S.; Stevens, Gerald D.; Tibbits, Aric; Turley, William D.

    2008-08-29

    Shock waves passing through a metal sample can produce ejecta particulates at a metal-vacuum interface. Holography records particle size distributions by using a high-power, short-pulse laser to freeze particle motion. The sizes of the ejecta particles are recorded using an in-line Fraunhofer holography technique. Because the holographic plate would be destroyed in an energetic environment, a high-resolution lens has been designed to relay the interference fringes to a safe environment. Particle sizes within a 12-mm-diameter, 5-mm-thick volume are recorded onto holographic film. To achieve resolution down to 0.5 μm, ultraviolet laser (UV) light is needed. The design and assembly of a nine-element lens that achieves >2000 lp/mm resolution and operates at f/0.89 will be described. To set up this lens system, a doublet lens is temporarily attached that enables operation with 532-nm laser light and 1100 lp/mm resolution. Thus, the setup and alignment are performed with green light, but the dynamic recording is done with UV light. During setup, the 532-nm beam provides enough focus shift to accommodate the placement of a resolution target outside the ejecta volume; this resolution target does not interfere with the calibrated wires and pegs surrounding the ejecta volume. A television microscope archives images of resolution patterns that prove that the calibration wires, interference filter, holographic plate, and relay lenses are in their correct positions. Part of this lens is under vacuum, at the point where the laser illumination passes through a focus. Alignment and tolerancing of this high-resolution lens will be presented, and resolution variation through the 5-mm depth of field will be discussed.

  18. Depth Estimation Using a Sliding Camera.

    PubMed

    Ge, Kailin; Hu, Han; Feng, Jianjiang; Zhou, Jie

    2016-02-01

    Image-based 3D reconstruction technology is widely used in different fields. The conventional algorithms are mainly based on stereo matching between two or more fixed cameras, and high accuracy can only be achieved using a large camera array, which is very expensive and inconvenient in many applications. Another popular choice is utilizing structure-from-motion methods for arbitrarily placed camera(s). However, due to too many degrees of freedom, its computational cost is heavy and its accuracy is rather limited. In this paper, we propose a novel depth estimation algorithm using a sliding camera system. By analyzing the geometric properties of the camera system, we design a camera pose initialization algorithm that can work satisfyingly with only a small number of feature points and is robust to noise. For pixels corresponding to different depths, an adaptive iterative algorithm is proposed to choose optimal frames for stereo matching, which can take advantage of continuously pose-changing imaging and save the time consumption amazingly too. The proposed algorithm can also be easily extended to handle less constrained situations (such as using a camera mounted on a moving robot or vehicle). Experimental results on both synthetic and real-world data have illustrated the effectiveness of the proposed algorithm. PMID:26685238

  19. Depth Estimation Using a Sliding Camera.

    PubMed

    Ge, Kailin; Hu, Han; Feng, Jianjiang; Zhou, Jie

    2016-02-01

    Image-based 3D reconstruction technology is widely used in different fields. The conventional algorithms are mainly based on stereo matching between two or more fixed cameras, and high accuracy can only be achieved using a large camera array, which is very expensive and inconvenient in many applications. Another popular choice is utilizing structure-from-motion methods for arbitrarily placed camera(s). However, due to too many degrees of freedom, its computational cost is heavy and its accuracy is rather limited. In this paper, we propose a novel depth estimation algorithm using a sliding camera system. By analyzing the geometric properties of the camera system, we design a camera pose initialization algorithm that can work satisfyingly with only a small number of feature points and is robust to noise. For pixels corresponding to different depths, an adaptive iterative algorithm is proposed to choose optimal frames for stereo matching, which can take advantage of continuously pose-changing imaging and save the time consumption amazingly too. The proposed algorithm can also be easily extended to handle less constrained situations (such as using a camera mounted on a moving robot or vehicle). Experimental results on both synthetic and real-world data have illustrated the effectiveness of the proposed algorithm.

  20. Selenographic distribution of apparent crater depth

    NASA Astrophysics Data System (ADS)

    de Hon, R. A.

    If apparent crater depth is a function of crater diameter, then the frequencies of crater depth and diameter should be similar and the distribution of apparent depths of craters on the lunar surface should be random. Apparent depths of complex craters, which range from 0.2 to 4.3 km on the moon, exhibit little correlation with crater diameters. Crater frequency decreases at increasing diameters, but apparent crater depth displays a Gaussian distribution. The average crater depth for all young craters is 1.8 km. The mean depth of craters on the maria is 1.3 km, and the mean depth of craters on the highlands is 2.1 km. A contour map of apparent crater depths exhibits sufficient organization to suggest that the apparent crater depth is correlated to major lunar provinces. In general, regions of shallow craters are associated with basin interiors. Greater apparent depths are associated with highland terrains.

  1. Long-range and depth-selective imaging of macroscopic targets using low-coherence and wide-field interferometry (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Woo, Sungsoo; Kang, Sungsam; Yoon, Changhyeong; Choi, Wonshik

    2016-03-01

    With the advancement of 3D display technology, 3D imaging of macroscopic objects has drawn much attention as they provide the contents to display. The most widely used imaging methods include a depth camera, which measures time of flight for the depth discrimination, and various structured illumination techniques. However, these existing methods have poor depth resolution, which makes imaging complicated structures a difficult task. In order to resolve this issue, we propose an imaging system based upon low-coherence interferometry and off-axis digital holographic imaging. By using light source with coherence length of 200 micro, we achieved the depth resolution of 100 micro. In order to map the macroscopic objects with this high axial resolution, we installed a pair of prisms in the reference beam path for the long-range scanning of the optical path length. Specifically, one prism was fixed in position, and the other prism was mounted on a translation stage and translated in parallel to the first prism. Due to the multiple internal reflections between the two prisms, the overall path length was elongated by a factor of 50. In this way, we could cover a depth range more than 1 meter. In addition, we employed multiple speckle illuminations and incoherent averaging of the acquired holographic images for reducing the specular reflections from the target surface. Using this newly developed system, we performed imaging targets with multiple different layers and demonstrated imaging targets hidden behind the scattering layers. The method was also applied to imaging targets located around the corner.

  2. Preliminary evaluation of a monolithic detector module for integrated PET/MRI scanner with high spatial resolution

    NASA Astrophysics Data System (ADS)

    Pani, R.; Gonzalez, A. J.; Bettiol, M.; Fabbri, A.; Cinti, M. N.; Preziosi, E.; Borrazzo, C.; Conde, P.; Pellegrini, R.; Di Castro, E.; Majewski, S.

    2015-06-01

    The proposal of Mindview European Project concerns with the development of a very high resolution and high efficiency brain dedicated PET scanner simultaneously working with a Magnetic Resonance scanner, that expects to visualize neurotransmitter pathways and their disruptions in the quest to better diagnose schizophrenia. On behalf of this project, we propose a low cost PET module for the first prototype, based on monolithic crystals, suitable to be integrated with a head Radio Frequency (RF) coil. The aim of the suggested module is to achieve high performances in terms of efficiency, planar spatial resolution (expected about 1 mm) and discrimination of gamma Depth Of Interaction (DOI) in order to reduce the parallax error. Our preliminary results are very promising: a DOI resolution of about 3 mm, a spatial resolution ranging from about 1 to 1.5 mm and a good position linearity.

  3. Electron microscopy at atomic resolution

    SciTech Connect

    Gronsky, R.

    1983-11-01

    The direct imaging of atomic structure in solids has become increasingly easier to accomplish with modern transmission electron microscopes, many of which have an information retrieval limit near 0.2 nm point resolution. Achieving better resolution, particularly with any useful range of specimen tilting, requires a major design effort. This presentation describes the new Atomic Resolution Microscope (ARM), recently put into operation at the Lawrence Berkeley Laboratory. Capable of 0.18 nm or better interpretable resolution over a voltage range of 400 kV to 1000 kV with +- 40/sup 0/ biaxial specimen tilting, the ARM features a number of new electron-optical and microprocessor-control designs. These are highlighted, and its atomic resolution performance demonstrated for a selection of inorganic crystals.

  4. Impact of high energy resolution detectors on the performance of a PET system dedicated to breast cancer imaging.

    PubMed

    Levin, Craig S; Foudray, Angela M K; Habte, Frezghi

    2006-01-01

    We are developing a high resolution, high sensitivity PET camera dedicated to breast cancer imaging. We are studying two novel detector technologies for this imaging system: a scintillation detector comprising layers of small lutetium oxyorthosilicate (LSO) crystals coupled to new position sensitive avalanche photodiodes (PSAPDs), and a pure semiconductor detector comprising cadmium zinc telluride (CZT) crystal slabs with thin anode and cathode strips deposited in orthogonal directions on either side of each slab. Both detectors achieve 1 mm spatial resolution with 3-5 mm directly measured photon interaction depth resolution, which promotes uniform reconstructed spatial resolution throughout a compact, breast-size field of view. Both detector types also achieve outstanding energy resolution (<3% and <12%, respectively for LSO-PSAPD and CZT at 511 keV). This paper studies the effects that this excellent energy resolution has on the expected system performance. Results indicate the importance that high energy resolution and narrow energy window settings have in reducing background random as well as scatter coincidences without compromising statistical quality of the dedicated breast PET data. Simulations predict that using either detector type the excellent performance and novel arrangement of these detectors proposed for the system facilitate approximately 20% instrument sensitivity at the system center and a peak noise-equivalent count rate of >4 kcps for 200 microCi in a simulated breast phantom. PMID:17645990

  5. Comparing Science Achievement Constructs: Targeted and Achieved

    ERIC Educational Resources Information Center

    Ferrara, Steve; Duncan, Teresa

    2011-01-01

    This article illustrates how test specifications based solely on academic content standards, without attention to other cognitive skills and item response demands, can fall short of their targeted constructs. First, the authors inductively describe the science achievement construct represented by a statewide sixth-grade science proficiency test.…

  6. Mobility and Reading Achievement.

    ERIC Educational Resources Information Center

    Waters, Theresa Z.

    A study examined the effect of geographic mobility on elementary school students' achievement. Although such mobility, which requires students to make multiple moves among schools, can have a negative impact on academic achievement, the hypothesis for the study was that it was not a determining factor in reading achievement test scores. Subjects…

  7. Focus cues affect perceived depth

    PubMed Central

    Watt, Simon J.; Akeley, Kurt; Ernst, Marc O.; Banks, Martin S.

    2007-01-01

    Depth information from focus cues—accommodation and the gradient of retinal blur—is typically incorrect in three-dimensional (3-D) displays because the light comes from a planar display surface. If the visual system incorporates information from focus cues into its calculation of 3-D scene parameters, this could cause distortions in perceived depth even when the 2-D retinal images are geometrically correct. In Experiment 1 we measured the direct contribution of focus cues to perceived slant by varying independently the physical slant of the display surface and the slant of a simulated surface specified by binocular disparity (binocular viewing) or perspective/texture (monocular viewing). In the binocular condition, slant estimates were unaffected by display slant. In the monocular condition, display slant had a systematic effect on slant estimates. Estimates were consistent with a weighted average of slant from focus cues and slant from disparity/texture, where the cue weights are determined by the reliability of each cue. In Experiment 2, we examined whether focus cues also have an indirect effect on perceived slant via the distance estimate used in disparity scaling. We varied independently the simulated distance and the focal distance to a disparity-defined 3-D stimulus. Perceived slant was systematically affected by changes in focal distance. Accordingly, depth constancy (with respect to simulated distance) was significantly reduced when focal distance was held constant compared to when it varied appropriately with the simulated distance to the stimulus. The results of both experiments show that focus cues can contribute to estimates of 3-D scene parameters. Inappropriate focus cues in typical 3-D displays may therefore contribute to distortions in perceived space. PMID:16441189

  8. Depth Estimation of Submerged Aquatic Vegetation in Clear Water Streams Using Low-Altitude Optical Remote Sensing.

    PubMed

    Visser, Fleur; Buis, Kerst; Verschoren, Veerle; Meire, Patrick

    2015-09-30

    UAVs and other low-altitude remote sensing platforms are proving very useful tools for remote sensing of river systems. Currently consumer grade cameras are still the most commonly used sensors for this purpose. In particular, progress is being made to obtain river bathymetry from the optical image data collected with such cameras, using the strong attenuation of light in water. No studies have yet applied this method to map submergence depth of aquatic vegetation, which has rather different reflectance characteristics from river bed substrate. This study therefore looked at the possibilities to use the optical image data to map submerged aquatic vegetation (SAV) depth in shallow clear water streams. We first applied the Optimal Band Ratio Analysis method (OBRA) of Legleiter et al. (2009) to a dataset of spectral signatures from three macrophyte species in a clear water stream. The results showed that for each species the ratio of certain wavelengths were strongly associated with depth. A combined assessment of all species resulted in equally strong associations, indicating that the effect of spectral variation in vegetation is subsidiary to spectral variation due to depth changes. Strongest associations (R²-values ranging from 0.67 to 0.90 for different species) were found for combinations including one band in the near infrared (NIR) region between 825 and 925 nm and one band in the visible light region. Currently data of both high spatial and spectral resolution is not commonly available to apply the OBRA results directly to image data for SAV depth mapping. Instead a novel, low-cost data acquisition method was used to obtain six-band high spatial resolution image composites using a NIR sensitive DSLR camera. A field dataset of SAV submergence depths was used to develop regression models for the mapping of submergence depth from image pixel values. Band (combinations) providing the best performing models (R²-values up to 0.77) corresponded with the OBRA

  9. Depth Estimation of Submerged Aquatic Vegetation in Clear Water Streams Using Low-Altitude Optical Remote Sensing

    PubMed Central

    Visser, Fleur; Buis, Kerst; Verschoren, Veerle; Meire, Patrick

    2015-01-01

    UAVs and other low-altitude remote sensing platforms are proving very useful tools for remote sensing of river systems. Currently consumer grade cameras are still the most commonly used sensors for this purpose. In particular, progress is being made to obtain river bathymetry from the optical image data collected with such cameras, using the strong attenuation of light in water. No studies have yet applied this method to map submergence depth of aquatic vegetation, which has rather different reflectance characteristics from river bed substrate. This study therefore looked at the possibilities to use the optical image data to map submerged aquatic vegetation (SAV) depth in shallow clear water streams. We first applied the Optimal Band Ratio Analysis method (OBRA) of Legleiter et al. (2009) to a dataset of spectral signatures from three macrophyte species in a clear water stream. The results showed that for each species the ratio of certain wavelengths were strongly associated with depth. A combined assessment of all species resulted in equally strong associations, indicating that the effect of spectral variation in vegetation is subsidiary to spectral variation due to depth changes. Strongest associations (R2-values ranging from 0.67 to 0.90 for different species) were found for combinations including one band in the near infrared (NIR) region between 825 and 925 nm and one band in the visible light region. Currently data of both high spatial and spectral resolution is not commonly available to apply the OBRA results directly to image data for SAV depth mapping. Instead a novel, low-cost data acquisition method was used to obtain six-band high spatial resolution image composites using a NIR sensitive DSLR camera. A field dataset of SAV submergence depths was used to develop regression models for the mapping of submergence depth from image pixel values. Band (combinations) providing the best performing models (R2-values up to 0.77) corresponded with the OBRA findings

  10. Seismic investigations for high resolution exploration ahead and around boreholes

    NASA Astrophysics Data System (ADS)

    Jaksch, Katrin; Giese, Ruediger; Kopf, Matthias

    2013-04-01

    Deep reservoirs usually will be explored with a surface seismic survey often in combination with borehole seismic measurements like VSP or SWD which can improve the velocity model of the underground. Reservoirs especially in geothermal fields are often characterized by small-scale structures. Additionally, with depth the need for exploration methods with a high resolution increases because standard methods like borehole seismic measurements cannot improve their resolution with depth. To localize structures with more accuracy methods with higher resolution in the range of meters are necessary. Within the project SPWD - Seismic Prediction While Drilling a new exploration method will be developed. With an implementation of seismic sources and receivers in one device an exploration method ahead and around the borehole will be enabled. Also, a high resolution independent from the depth will be achieved. Therefore active and powerful seismic sources are necessary to reach an acceptable penetration depth. Step by step seismic borehole devices were developed, which can be used under different conditions. Every borehole device contains four seismic sources and several three-component geophones. A small distance between actuators and geophones allows detecting also the high frequency content of the wave field reflected at geological structures. Also, exploration with a high resolution is possible. A first borehole device was developed for basic conditions in horizontal boreholes without special terms to temperature or pressure. In a mine first methodical measurements for the initiated wave field were performed. Therefor an existing seismic test area at the research and education mine of the TU Bergakademie Freiberg was extended with boreholes. In the seismic test area, consisting of a dense geophone array with three-component geophone anchors, two horizontal and one vertical borehole was drilled. To achieve a radiation pattern in predefined directions by constructive

  11. Coherent transfer functions and extended depth of field

    NASA Astrophysics Data System (ADS)

    Villiger, M.; Pache, C.; Leitgeb, Rainer A.; Lasser, Theo

    2010-02-01

    To preserve the speed advantage of Fourier Domain detection in Optical Coherence Microscopy (OCM), extended depth of field (DOF) is needed. To assess and improve the DOF and the lateral resolution, we analyzed the coherent transfer function (CTF) of OCM. In the spectral domain detection, each wavelength has its own specific CTF, sampling a different part of the object's spatial frequency spectrum. For classical optics and increasing numerical apertures these regions start to overlap and bend, which limits the depth of field. Bessel-like beams produced by axicon lenses circumvent these detrimental effects, but introduce side lobes. Decoupling the detection and the illumination apertures gives more flexibility in engineering a CTF and optimizes the lateral resolution and the DOF at the same time all while reducing these side lobes. We evaluated different combinations of Gaussian and Bessel-like illumination and detection optics. Using Bessel-like beams as well in the illumination as in the detection paths, but with different side-lobe radii, we obtained a lateral resolution of 2μm invariant over an extended depth of field of more than 300μm, at a signal penalty of only 12dB compared to classical Gaussian optics.

  12. Monocular catadioptric panoramic depth estimation via caustics-based virtual scene transition.

    PubMed

    He, Yu; Wang, Lingxue; Cai, Yi; Xue, Wei

    2016-09-01

    Existing catadioptric panoramic depth estimation systems usually require two panoramic imaging subsystems to achieve binocular disparity. The system structures are complicated and only sparse depth maps can be obtained. We present a novel monocular catadioptric panoramic depth estimation method that achieves dense depth maps of panoramic scenes using a single unmodified conventional catadioptric panoramic imaging system. Caustics model the reflection of the curved mirror and establish the distance relationship between the virtual and real panoramic scenes to overcome the nonlinear problem of the curved mirror. Virtual scene depth is then obtained by applying our structure classification regularization to depth from defocus. Finally, real panoramic scene depth is recovered using the distance relationship. Our method's effectiveness is demonstrated in experiments. PMID:27607512

  13. Multi-depth photoacoustic microscopy with a focus tunable lens

    NASA Astrophysics Data System (ADS)

    Lee, Kiri; Chung, Euiheon; Eom, Tae Joong

    2015-03-01

    Optical-resolution photoacoustic microscopy (OR-PAM) has been studied to improve its imaging resolution and functional imaging modality without labeling on biology sample. However the use of high numerical aperture (NA) objective lens confines the field of view or the axial imaging range of OR-PAM. In order to obtain images at different layers, one needs to change either the sample position or the focusing position by mechanical scanning. This mechanical movement of the sample or the objective lens limits the scanning speed and the positioning precision. In this study, we propose a multi-depth PAM with a focus tunable lens. We electrically adjusted the focal length in the depth direction of the sample, and twice extended the axial imaging range up to 660 μm with the objective lens (20X, NA 0.4). The proposed approach can increase scanning speed and avoid step motor induced distortions during PA signal acquisitions without mechanical scanning in the depth direction. To investigate the performance of the multi-depth PAM system, we scanned a black human hair and the ear of a living nude mouse (BALB/c Nude). The obtained PAM images presented the volumetric rendering of black hair and the vasculature of the nude mouse.

  14. Feasibility of high-resolution one-dimensional relaxation imaging at low magnetic field using a single-sided NMR scanner applied to articular cartilage

    NASA Astrophysics Data System (ADS)

    Rössler, Erik; Mattea, Carlos; Stapf, Siegfried

    2015-02-01

    Low field Nuclear Magnetic Resonance increases the contrast of the longitudinal relaxation rate in many biological tissues; one prominent example is hyaline articular cartilage. In order to take advantage of this increased contrast and to profile the depth-dependent variations, high resolution parameter measurements are carried out which can be of critical importance in an early diagnosis of cartilage diseases such as osteoarthritis. However, the maximum achievable spatial resolution of parameter profiles is limited by factors such as sensor geometry, sample curvature, and diffusion limitation. In this work, we report on high-resolution single-sided NMR scanner measurements with a commercial device, and quantify these limitations. The highest achievable spatial resolution on the used profiler, and the lateral dimension of the sensitive volume were determined. Since articular cartilage samples are usually bent, we also focus on averaging effects inside the horizontally aligned sensitive volume and their impact on the relaxation profiles. Taking these critical parameters into consideration, depth-dependent relaxation time profiles with the maximum achievable vertical resolution of 20 μm are discussed, and are correlated with diffusion coefficient profiles in hyaline articular cartilage in order to reconstruct T2 maps from the diffusion-weighted CPMG decays of apparent relaxation rates.

  15. Multi-sensor super-resolution for hybrid range imaging with application to 3-D endoscopy and open surgery.

    PubMed

    Köhler, Thomas; Haase, Sven; Bauer, Sebastian; Wasza, Jakob; Kilgus, Thomas; Maier-Hein, Lena; Stock, Christian; Hornegger, Joachim; Feußner, Hubertus

    2015-08-01

    In this paper, we propose a multi-sensor super-resolution framework for hybrid imaging to super-resolve data from one modality by taking advantage of additional guidance images of a complementary modality. This concept is applied to hybrid 3-D range imaging in image-guided surgery, where high-quality photometric data is exploited to enhance range images of low spatial resolution. We formulate super-resolution based on the maximum a-posteriori (MAP) principle and reconstruct high-resolution range data from multiple low-resolution frames and complementary photometric information. Robust motion estimation as required for super-resolution is performed on photometric data to derive displacement fields of subpixel accuracy for the associated range images. For improved reconstruction of depth discontinuities, a novel adaptive regularizer exploiting correlations between both modalities is embedded to MAP estimation. We evaluated our method on synthetic data as well as ex-vivo images in open surgery and endoscopy. The proposed multi-sensor framework improves the peak signal-to-noise ratio by 2 dB and structural similarity by 0.03 on average compared to conventional single-sensor approaches. In ex-vivo experiments on porcine organs, our method achieves substantial improvements in terms of depth discontinuity reconstruction.

  16. Submicron-resolution photoacoustic microscopy of endogenous light-absorbing biomolecules

    NASA Astrophysics Data System (ADS)

    Zhang, Chi

    Photoacoustic imaging in biomedicine has the unique advantage of probing endogenous light absorbers at various length scales with a 100% relative sensitivity. Among the several modalities of photoacoustic imaging, optical-resolution photoacoustic microscopy (OR-PAM) can achieve high spatial resolution, on the order of optical wavelength, at <1 mm depth in biological tissue (the optical ballistic regime). OR-PAM has been applied successfully to structural and functional imaging of blood vasculature and red blood cells in vivo. Any molecules which absorb sufficient light at certain wavelengths can potentially be imaged by PAM. Compared with pure optical imaging, which typically targets fluorescent markers, label-free PAM avoids the major concerns that the fluorescent labeling probes may disturb the function of biomolecules and may have an insufficient density. This dissertation aims to advance label-free OR-PAM to the subcellular scale. The first part of this dissertation describes the technological advancement of PAM yielding high spatial resolution in 3D. The lateral resolution was improved by using optical objectives with high numerical apertures for optical focusing. The axial resolution was improved by using broadband ultrasonic transducers for ultrasound detection. We achieved 220 nm lateral resolution in transmission mode, 0.43 microm lateral resolution in reflection mode, 7.6 microm axial resolution in normal tissue, and 5.8 microm axial resolution with silicone oil immersion/injection. The achieved lateral resolution and axial resolution were the finest reported at the time. With high-resolution in 3D, PAM was demonstrated to resolve cellular and subcellular structures in vivo, such as red blood cells and melanosomes in melanoma cells. Compared with previous PAM systems, our high-resolution PAM could resolve capillaries in mouse ears more clearly. As an example application, we demonstrated intracellular temperature imaging, assisted by fluorescence signal

  17. Conference Resolution

    NASA Astrophysics Data System (ADS)

    2009-04-01

    Since the first IUPAP International Conference on Women in Physics (Paris, March 2002) and the Second Conference (Rio de Janeiro, May 2005), progress has continued in most countries and world regions to attract girls to physics and advance women into leadership roles, and many working groups have formed. The Third Conference (Seoul, October 2008), with 283 attendees from 57 countries, was dedicated to celebrating the physics achievements of women throughout the world, networking toward new international collaborations, building each participant's capacity for career success, and aiding the formation of active regional working groups to advance women in physics. Despite the progress, women remain a small minority of the physics community in most countries.

  18. Total variation based image deconvolution for extended depth-of-field microscopy images

    NASA Astrophysics Data System (ADS)

    Hausser, F.; Beckers, I.; Gierlak, M.; Kahraman, O.

    2015-03-01

    One approach for a detailed understanding of dynamical cellular processes during drug delivery is the use of functionalized biocompatible nanoparticles and fluorescent markers. An appropriate imaging system has to detect these moving particles so as whole cell volumes in real time with high lateral resolution in a range of a few 100 nm. In a previous study Extended depth-of-field microscopy (EDF-microscopy) has been applied to fluorescent beads and tradiscantia stamen hair cells and the concept of real-time imaging has been proved in different microscopic modes. In principle a phase retardation system like a programmable space light modulator or a static waveplate is incorporated in the light path and modulates the wavefront of light. Hence the focal ellipsoid is smeared out and images seem to be blurred in a first step. An image restoration by deconvolution using the known point-spread-function (PSF) of the optical system is necessary to achieve sharp microscopic images of an extended depth-of-field. This work is focused on the investigation and optimization of deconvolution algorithms to solve this restoration problem satisfactorily. This inverse problem is challenging due to presence of Poisson distributed noise and Gaussian noise, and since the PSF used for deconvolution exactly fits in just one plane within the object. We use non-linear Total Variation based image restoration techniques, where different types of noise can be treated properly. Various algorithms are evaluated for artificially generated 3D images as well as for fluorescence measurements of BPAE cells.

  19. Spatial resolution recovery utilizing multi-ray tracing and graphic processing unit in PET image reconstruction.

    PubMed

    Liang, Yicheng; Peng, Hao

    2015-02-01

    Depth-of-interaction (DOI) poses a major challenge for a PET system to achieve uniform spatial resolution across the field-of-view, particularly for small animal and organ-dedicated PET systems. In this work, we implemented an analytical method to model system matrix for resolution recovery, which was then incorporated in PET image reconstruction on a graphical processing unit platform, due to its parallel processing capacity. The method utilizes the concepts of virtual DOI layers and multi-ray tracing to calculate the coincidence detection response function for a given line-of-response. The accuracy of the proposed method was validated for a small-bore PET insert to be used for simultaneous PET/MR breast imaging. In addition, the performance comparisons were studied among the following three cases: 1) no physical DOI and no resolution modeling; 2) two physical DOI layers and no resolution modeling; and 3) no physical DOI design but with a different number of virtual DOI layers. The image quality was quantitatively evaluated in terms of spatial resolution (full-width-half-maximum and position offset), contrast recovery coefficient and noise. The results indicate that the proposed method has the potential to be used as an alternative to other physical DOI designs and achieve comparable imaging performances, while reducing detector/system design cost and complexity.

  20. All-near-infrared multiphoton microscopy interrogates intact tissues at deeper imaging depths than conventional single- and two-photon near-infrared excitation microscopes.

    PubMed

    Sarder, Pinaki; Yazdanfar, Siavash; Akers, Walter J; Tang, Rui; Sudlow, Gail P; Egbulefu, Christopher; Achilefu, Samuel

    2013-10-01

    The era of molecular medicine has ushered in the development of microscopic methods that can report molecular processes in thick tissues with high spatial resolution. A commonality in deep-tissue microscopy is the use of near-infrared (NIR) lasers with single- or multiphoton excitations. However, the relationship between different NIR excitation microscopic techniques and the imaging depths in tissue has not been established. We compared such depth limits for three NIR excitation techniques: NIR single-photon confocal microscopy (NIR SPCM), NIR multiphoton excitation with visible detection (NIR/VIS MPM), and all-NIR multiphoton excitation with NIR detection (NIR/NIR MPM). Homologous cyanine dyes provided the fluorescence. Intact kidneys were harvested after administration of kidney-clearing cyanine dyes in mice. NIR SPCM and NIR/VIS MPM achieved similar maximum imaging depth of ∼100 μm. The NIR/NIR MPM enabled greater than fivefold imaging depth (>500 μm) using the harvested kidneys. Although the NIR/NIR MPM used 1550-nm excitation where water absorption is relatively high, cell viability and histology studies demonstrate that the laser did not induce photothermal damage at the low laser powers used for the kidney imaging. This study provides guidance on the imaging depth capabilities of NIR excitation-based microscopic techniques and reveals the potential to multiplex information using these platforms.

  1. Depth-resolved x-ray absorption fine structure study of Fe/Si interfaces using x-ray standing waves

    SciTech Connect

    Gupta, Ajay; Rajput, Parasmani; Meneghini, Carlo

    2007-11-15

    X-ray standing waves generated by total external reflection (TER) from an underlayer of Au have been used to perform depth resolved x-ray absorption fine structure (XAFS) studies on a Si/Fe/Si trilayer in which intermixing has been induced by irradiation with 100 MeV Au ions. It is demonstrated that the technique has a sufficient depth resolution so as to elucidate the depth distribution of various phases formed across the interfaces. Irradiation to a fluence of 1x10{sup 13} ions/cm{sup 2} results in complete mixing of the Fe layer. It is observed that in the center of the intermixed layer, the short-range order around Fe ions is similar to the FeSi phase. Moving away from the center, Si concentration increases and the local structure around Fe becomes similar to that of the FeSi{sub 2} phase. On the other hand, depth integrated XAFS data could have been interpreted in terms of a homogeneous FeSi{sub 2} type of short-range order in the system. Thus, the depth selectivity achieved using TER standing waves combined with the sensitivity of XAFS to local order around a specific element makes it a valuable tool for studying layered materials.

  2. Resolution in forensic microbial genotyping

    SciTech Connect

    Velsko, S P

    2005-08-30

    Resolution is a key parameter for differentiating among the large number of strain typing methods that could be applied to pathogens involved in bioterror events or biocrimes. In this report we develop a first-principles analysis of strain typing resolution using a simple mathematical model to provide a basis for the rational design of microbial typing systems for forensic applications. We derive two figures of merit that describe the resolving power and phylogenetic depth of a strain typing system. Rough estimates of these figures-of-merit for MLVA, MLST, IS element, AFLP, hybridization microarrays, and other bacterial typing methods are derived from mutation rate data reported in the literature. We also discuss the general problem of how to construct a ''universal'' practical typing system that has the highest possible resolution short of whole-genome sequencing, and that is applicable with minimal modification to a wide range of pathogens.

  3. Joint geodesic depth propagation for two-dimensional-to-three-dimensional video conversion

    NASA Astrophysics Data System (ADS)

    Jung, Cheolkon; Cai, Jiji

    2016-01-01

    We propose joint geodesic depth propagation (JGDP) for two-dimensional-to-three-dimensional video conversion. To save substantial human effort and produce high-quality depth maps, we adopt a key-frame depth propagation strategy based on a geodesic distance. First, we perform block matching between current and reference frames to estimate motion vectors (MVs). Second, we conduct depth compensation from the reference depth map for obtaining the current depth map based on MVs. Finally, we refine the depth map using joint geodesic filtering. Experimental results demonstrate that JGDP achieves an average 2.4-dB gain in peak-signal-to-noise ratio and 0.019 gain in structure similarity over state-of-the-art depth propagation methods.

  4. High-dimensional camera shake removal with given depth map.

    PubMed

    Yue, Tao; Suo, Jinli; Dai, Qionghai

    2014-06-01

    Camera motion blur is drastically nonuniform for large depth-range scenes, and the nonuniformity caused by camera translation is depth dependent but not the case for camera rotations. To restore the blurry images of large-depth-range scenes deteriorated by arbitrary camera motion, we build an image blur model considering 6-degrees of freedom (DoF) of camera motion with a given scene depth map. To make this 6D depth-aware model tractable, we propose a novel parametrization strategy to reduce the number of variables and an effective method to estimate high-dimensional camera motion as well. The number of variables is reduced by temporal sampling motion function, which describes the 6-DoF camera motion by sampling the camera trajectory uniformly in time domain. To effectively estimate the high-dimensional camera motion parameters, we construct the probabilistic motion density function (PMDF) to describe the probability distribution of camera poses during exposure, and apply it as a unified constraint to guide the convergence of the iterative deblurring algorithm. Specifically, PMDF is computed through a back projection from 2D local blur kernels to 6D camera motion parameter space and robust voting. We conduct a series of experiments on both synthetic and real captured data, and validate that our method achieves better performance than existing uniform methods and nonuniform methods on large-depth-range scenes.

  5. Predefined Redundant Dictionary for Effective Depth Maps Representation

    NASA Astrophysics Data System (ADS)

    Sebai, Dorsaf; Chaieb, Faten; Ghorbel, Faouzi

    2016-01-01

    The multi-view video plus depth (MVD) video format consists of two components: texture and depth map, where a combination of these components enables a receiver to generate arbitrary virtual views. However, MVD presents a very voluminous video format that requires a compression process for storage and especially for transmission. Conventional codecs are perfectly efficient for texture images compression but not for intrinsic depth maps properties. Depth images indeed are characterized by areas of smoothly varying grey levels separated by sharp discontinuities at the position of object boundaries. Preserving these characteristics is important to enable high quality view synthesis at the receiver side. In this paper, sparse representation of depth maps is discussed. It is shown that a significant gain in sparsity is achieved when particular mixed dictionaries are used for approximating these types of images with greedy selection strategies. Experiments are conducted to confirm the effectiveness at producing sparse representations, and competitiveness, with respect to candidate state-of-art dictionaries. Finally, the resulting method is shown to be effective for depth maps compression and represents an advantage over the ongoing 3D high efficiency video coding compression standard, particularly at medium and high bitrates.

  6. Foundation Depth for Bridge Piers

    NASA Astrophysics Data System (ADS)

    Veerappadevaru, G.; Gangadharaiah, T.; Jagadeesh, T. R.

    2013-09-01

    The safety of bridge piers built in rivers having the bed is one of the prime aspects in the study of scouring process around bridge piers. The stability of bridge piers depends on the depth of foundation provided below maximum scour level. The stability analysis of bridge piers is carried based on moment of forces acting on the caisson pier when the pier slides and tilts slightly in downstream from its position. The experiments are conducted for three pier shapes on two sediment beds and for different flow conditions. The curves indicating the stability limits are compared with Lacey's recommendations which are used in present day practice in India. The analysis presented here indicates that the Lacey's recommendation for railway bridges is safe and for some cases of the road bridges depends on grip length, angle of tilt and weight of caisson.

  7. Aeration equipment for small depths

    NASA Astrophysics Data System (ADS)

    Sluše, Jan; Pochylý, František

    2015-05-01

    Deficit of air in water causes complications with cyanobacteria mainly in the summer months. Cyanobacteria is a bacteria that produces poison called cyanotoxin. When the concentration of cyanobacteria increases, the phenomena "algal bloom" appears, which is very toxic and may kill all the organisms. This article describes new equipment for aeration of water in dams, ponds and reservoirs with small depth. This equipment is mobile and it is able to work without any human factor because its control is provided by a GPS module. The main part of this equipment consists of a floating pump which pumps water from the surface. Another important part of this equipment is an aerator where water and air are blended. Final aeration process runs in the nozzles which provide movement of all this equipment and aeration of the water. Simulations of the flow are solved by multiphase flow with diffusion in open source program called OpenFOAM. Results will be verified by an experiment.

  8. Measuring depth profiles of residual stress with Raman spectroscopy

    SciTech Connect

    Enloe, W.S.; Sparks, R.G.; Paesler, M.A.

    1988-12-01

    Knowledge of the variation of residual stress is a very important factor in understanding the properties of machined surfaces. The nature of the residual stress can determine a part`s susceptibility to wear deformation, and cracking. Raman spectroscopy is known to be a very useful technique for measuring residual stress in many materials. These measurements are routinely made with a lateral resolution of 1{mu}m and an accuracy of 0.1 kbar. The variation of stress with depth; however, has not received much attention in the past. A novel technique has been developed that allows quantitative measurement of the variation of the residual stress with depth with an accuracy of 10nm in the z direction. Qualitative techniques for determining whether the stress is varying with depth are presented. It is also demonstrated that when the stress is changing over the volume sampled, errors can be introduced if the variation of the stress with depth is ignored. Computer aided data analysis is used to determine the depth dependence of the residual stress.

  9. Metrology aspects of SIMS depth profiling for advanced ULSI processes

    SciTech Connect

    Budrevich, Andre; Hunter, Jerry

    1998-11-24

    As the semiconductor industry roadmap passes through the 0.1 {mu}m technology node, the junction depth of the transistor source/drain extension will be required to be less than 20 nm and the well doping will be near 1.0 {mu}m in depth. The development of advanced ULSI processing techniques requires the evolution of new metrology tools to ensure process capability. High sensitivity (ppb) coupled with excellent depth resolution (1 nm) makes SIMS the technique of choice for measuring the in-depth chemical distribution of these dopants with high precision and accuracy. This paper will discuss the issues, which impact the accuracy and precision of SIMS measurements of ion implants (both shallow and deep). First this paper will discuss common uses of the SIMS technique in the technology development and manufacturing of advanced ULSI processes. In the second part of this paper the ability of SIMS to make high precision measurements of ion implant depth profiles will be studied.

  10. Modeling of multi-depth slanted airgun source for deghosting

    NASA Astrophysics Data System (ADS)

    Shen, Hong-Lei; Elboth, Thomas; Tian, Gang; Lin, Zhi

    2014-12-01

    To obtain high-resolution of the subsurface structure, we modeled multi-depth slanted airgun sources to attenuate the source ghost. By firing the guns in sequence according to their relative depths, such a source can build constructive primaries and destructive ghosts. To evaluate the attenuation of ghosts, the normalized squared error of the spectrum of the actual vs the expected signature is computed. We used a typical 680 cu.in airgun string and found via simulations that a depth interval of 1 or 1.5 m between airguns is optimum when considering deghosting performance and operational feasibility. When more subarrays are combined, preliminary simulations are necessary to determine the optimum depth combination. The frequency notches introduced by the excess use of subarrays may negatively affect the deghosting performance. Two or three slanted subarrays can be combined to remove the ghost effect. The sequence combination may partly affect deghosting but this can be eliminated by matched filtering. Directivity comparison shows that a multi-depth slanted source can significantly attenuate the notches and widen the energy transmission stability area.

  11. Large area and depth-profiling dislocation imaging and strain analysis in Si/SiGe/Si heterostructures.

    PubMed

    Chen, Xin; Zuo, Daniel; Kim, Seongwon; Mabon, James; Sardela, Mauro; Wen, Jianguo; Zuo, Jian-Min

    2014-10-01

    We demonstrate the combined use of large area depth-profiling dislocation imaging and quantitative composition and strain measurement for a strained Si/SiGe/Si sample based on nondestructive techniques of electron beam-induced current (EBIC) and X-ray diffraction reciprocal space mapping (XRD RSM). Depth and improved spatial resolution is achieved for dislocation imaging in EBIC by using different electron beam energies at a low temperature of ~7 K. Images recorded clearly show dislocations distributed in three regions of the sample: deep dislocation networks concentrated in the "strained" SiGe region, shallow misfit dislocations at the top Si/SiGe interface, and threading dislocations connecting the two regions. Dislocation densities at the top of the sample can be measured directly from the EBIC results. XRD RSM reveals separated peaks, allowing a quantitative measurement of composition and strain corresponding to different layers of different composition ratios. High-resolution scanning transmission electron microscopy cross-section analysis clearly shows the individual composition layers and the dislocation lines in the layers, which supports the EBIC and XRD RSM results.

  12. High resolution telescope

    DOEpatents

    Massie, Norbert A.; Oster, Yale

    1992-01-01

    A large effective-aperture, low-cost optical telescope with diffraction-limited resolution enables ground-based observation of near-earth space objects. The telescope has a non-redundant, thinned-aperture array in a center-mount, single-structure space frame. It employs speckle interferometric imaging to achieve diffraction-limited resolution. The signal-to-noise ratio problem is mitigated by moving the wavelength of operation to the near-IR, and the image is sensed by a Silicon CCD. The steerable, single-structure array presents a constant pupil. The center-mount, radar-like mount enables low-earth orbit space objects to be tracked as well as increases stiffness of the space frame. In the preferred embodiment, the array has elemental telescopes with subaperture of 2.1 m in a circle-of-nine configuration. The telescope array has an effective aperture of 12 m which provides a diffraction-limited resolution of 0.02 arc seconds. Pathlength matching of the telescope array is maintained by an electro-optical system employing laser metrology. Speckle imaging relaxes pathlength matching tolerance by one order of magnitude as compared to phased arrays. Many features of the telescope contribute to substantial reduction in costs. These include eliminating the conventional protective dome and reducing on-site construction activites. The cost of the telescope scales with the first power of the aperture rather than its third power as in conventional telescopes.

  13. Relations between heat flow, topography and Moho depth for Europe

    NASA Astrophysics Data System (ADS)

    Polkowski, Marcin; Majorowicz, Jacek; Grad, Marek

    2013-04-01

    The relation between heat flow, topography and Moho depth for recent maps of Europe is presented. New heat flow map of Europe (Majorowicz and Wybraniec, 2010) is based on updated database of uncorrected heat flow values to which paleoclimatic correction is applied across the continental Europe. Correction is depth dependent due to a diffusive thermal transfer of the surface temperature forcing of which glacial-interglacial history has the largest impact. This explains some very low uncorrected heat flow values 20-30 mW/m2 in the shields, shallow basin areas of the cratons, and in other areas including orogenic belts were heat flow was likely underestimated. New integrated map of the European Moho depth (Grad et al., 2009) is the first high resolution digital map for European plate understand as an area from Ural Mountains in the east to mid-Atlantic ridge in the west, and Mediterranean Sea in the south to Spitsbergen and Barents Sea in Arctic in the north. For correlation we used: onshore heat flow density data with palaeoclimatic correction (5318 locations), topography map (30 x 30 arc seconds; Danielson and Gesch, 2011) and Moho map (longitude, latitude and Moho depth, each 0.1 degree). Analysis was done in areas where data from all three datasets were available. Continental Europe area could be divided into two large domains related with Precambrian East European craton and Palaeozoic Platform. Next two smaller areas correspond to Scandinavian Caledonides and Anatolia. Presented results show different correlations between Moho depth, elevation and heat flow for all discussed regions. For each region more detailed analysis of these relation in different elevation ranges is presented. In general it is observed that Moho depth is more significant to HF then elevation. Depending on region and elevation range HF value in mW/m2 is up to two times larger than Moho depth in km, while HF relation to elevation varies much more.

  14. Airborne Surveys of Snow Depth over Arctic Sea Ice

    NASA Technical Reports Server (NTRS)

    Kwok, R.; Panzer, B.; Leuschen, C.; Pang, S.; Markus, T.; Holt, B.; Gogineni, S.

    2011-01-01

    During the spring of 2009, an ultrawideband microwave radar was deployed as part of Operation IceBridge to provide the first cross-basin surveys of snow thickness over Arctic sea ice. In this paper, we analyze data from three approx 2000 km transects to examine detection issues, the limitations of the current instrument, and the regional variability of the retrieved snow depth. Snow depth is the vertical distance between the air \\snow and snow-ice interfaces detected in the radar echograms. Under ideal conditions, the per echogram uncertainty in snow depth retrieval is approx 4 - 5 cm. The finite range resolution of the radar (approx 5 cm) and the relative amplitude of backscatter from the two interfaces limit the direct retrieval of snow depths much below approx 8 cm. Well-defined interfaces are observed over only relatively smooth surfaces within the radar footprint of approx 6.5 m. Sampling is thus restricted to undeformed, level ice. In early April, mean snow depths are 28.5 +/- 16.6 cm and 41.0 +/- 22.2 cm over first-year and multiyear sea ice (MYI), respectively. Regionally, snow thickness is thinner and quite uniform over the large expanse of seasonal ice in the Beaufort Sea, and gets progressively thicker toward the MYI cover north of Ellesmere Island, Greenland, and the Fram Strait. Snow depth over MYI is comparable to that reported in the climatology by Warren et al. Ongoing improvements to the radar system and the utility of these snow depth measurements are discussed.

  15. The effects of reduced bit depth on optical coherence tomography phase data.

    PubMed

    Ling, William A; Ellerbee, Audrey K

    2012-07-01

    Past studies of the effects of bit depth on OCT magnitude data concluded that 8 bits of digitizer resolution provided nearly the same image quality as a 14-bit digitizer. However, such studies did not assess the effects of bit depth on the accuracy of phase data. In this work, we show that the effects of bit depth on phase data and magnitude data can differ significantly. This finding has an important impact on the design of phase-resolved OCT systems, such as those measuring motion and the birefringence of samples, particularly as one begins to consider the tradeoff between bit depth and digitizer speed.

  16. Case depth verification of hardened samples with Barkhausen noise sweeps

    SciTech Connect

    Santa-aho, Suvi; Vippola, Minnamari; Lepistö, Toivo; Hakanen, Merja; Sorsa, Aki; Leiviskä, Kauko

    2014-02-18

    An interesting topic of recent Barkhausen noise (BN) method studies is the application of the method to case depth evaluation of hardened components. The utilization of BN method for this purpose is based on the difference in the magnetic properties between the hardened case and the soft core. Thus, the detection of case depth with BN can be achieved. The measurements typically have been carried out by using low magnetizing frequencies which have deeper penetration to the ferromagnetic samples than the conventional BN measurement. However, the penetration depth is limited due to eddy current damping of the signal. We introduce here a newly found sweep measurement concept for the case depth evaluation. In this study sweep measurements were carried out with various magnetizing frequencies and magnetizing voltages to detect the effect of different frequency and voltage and their correspondence to the actual case depth values verified from destructive characterization. Also a BN measurement device that has an implemented sweep analysis option was utilised. The samples were either induction or case-hardened samples and sample geometry contained both rod samples and gear axle samples with different case depth values. Samples were also further characterized with Xray diffraction to study the residual stress state of the surface. The detailed data processing revealed that also other calculated features than the maximum slope division of the 1st derivative of the BN signal could hold the information about the case depth value of the samples. The sweep method was able to arrange the axles into correct order according to the case depth value even though the axles were used.

  17. Blending satellite-based snow depth products with in situ observations for streamflow predictions in the Upper Colorado River Basin

    NASA Astrophysics Data System (ADS)

    Liu, Yuqiong; Peters-Lidard, Christa D.; Kumar, Sujay V.; Arsenault, Kristi R.; Mocko, David M.

    2015-02-01

    In snowmelt-driven river systems, it is critical to enable reliable predictions of the spatiotemporal variability in seasonal snowpack to support local and regional water management. Previous studies have shown that assimilating satellite-station blended snow depth data sets can lead to improved snow predictions, which however do not always translate into improved streamflow predictions, especially in complex mountain regions. In this study, we explore how an existing optimal interpolation-based blending strategy can be enhanced to reduce biases in satellite snow depth products for improving streamflow predictions. Two major new considerations are explored, including: (1) incorporating terrain aspect and (2) incorporating areal snow coverage information. The methodology is applied to the bias reduction of the Advanced Microwave Scanning Radiometer for the Earth Observing System (AMSR-E) snow depth estimates, which are then assimilated into the Noah land surface model via the ensemble Kalman Filtering (EnKF) for streamflow predictions in the Upper Colorado River Basin. Our results indicate that using only observations from low-elevation stations such as the Global Historical Climatology Network (GHCN) in the bias correction can lead to underestimation in streamflow, while using observations from high-elevation stations (e.g., the Snow Telemetry (SNOTEL) network) along with terrain aspect is critically important for achieving reliable streamflow predictions. Additionally incorporating areal snow coverage information from the Moderate Resolution Imaging Spectroradiometer (MODIS) can slightly improve the streamflow results further.

  18. General Achievement Trends: Oklahoma

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  19. General Achievement Trends: Georgia

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  20. General Achievement Trends: Nebraska

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  1. General Achievement Trends: Arkansas

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  2. General Achievement Trends: Maryland

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  3. General Achievement Trends: Maine

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  4. General Achievement Trends: Iowa

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  5. General Achievement Trends: Texas

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  6. General Achievement Trends: Hawaii

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  7. General Achievement Trends: Kansas

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  8. General Achievement Trends: Florida

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  9. General Achievement Trends: Massachusetts

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  10. General Achievement Trends: Tennessee

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  11. General Achievement Trends: Alabama

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  12. General Achievement Trends: Virginia

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  13. General Achievement Trends: Michigan

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  14. General Achievement Trends: Colorado

    ERIC Educational Resources Information Center

    Center on Education Policy, 2009

    2009-01-01

    This general achievement trends profile includes information that the Center on Education Policy (CEP) and the Human Resources Research Organization (HumRRO) obtained from states from fall 2008 through April 2009. Included herein are: (1) Bullet points summarizing key findings about achievement trends in that state at three performance…

  15. Inverting the Achievement Pyramid

    ERIC Educational Resources Information Center

    White-Hood, Marian; Shindel, Melissa

    2006-01-01

    Attempting to invert the pyramid to improve student achievement and increase all students' chances for success is not a new endeavor. For decades, educators have strategized, formed think tanks, and developed school improvement teams to find better ways to improve the achievement of all students. Currently, the No Child Left Behind Act (NCLB) is…

  16. Achievement Test Program.

    ERIC Educational Resources Information Center

    Ohio State Dept. of Education, Columbus. Trade and Industrial Education Service.

    The Ohio Trade and Industrial Education Achievement Test battery is comprised of seven basic achievement tests: Machine Trades, Automotive Mechanics, Basic Electricity, Basic Electronics, Mechanical Drafting, Printing, and Sheet Metal. The tests were developed by subject matter committees and specialists in testing and research. The Ohio Trade and…

  17. School Effects on Achievement.

    ERIC Educational Resources Information Center

    Nichols, Robert C.

    The New York State Education Department conducts a Pupil Evaluation Program (PEP) in which each year all third, sixth, and ninth grade students in the state are given a series of achievement tests in reading and mathematics. The data accumulated by the department includes achievement test scores, teacher characteristics, building and curriculum…

  18. Heritability of Creative Achievement

    ERIC Educational Resources Information Center

    Piffer, Davide; Hur, Yoon-Mi

    2014-01-01

    Although creative achievement is a subject of much attention to lay people, the origin of individual differences in creative accomplishments remain poorly understood. This study examined genetic and environmental influences on creative achievement in an adult sample of 338 twins (mean age = 26.3 years; SD = 6.6 years). Twins completed the Creative…

  19. Confronting the Achievement Gap

    ERIC Educational Resources Information Center

    Gardner, David

    2007-01-01

    This article talks about the large achievement gap between children of color and their white peers. The reasons for the achievement gap are varied. First, many urban minorities come from a background of poverty. One of the detrimental effects of growing up in poverty is receiving inadequate nourishment at a time when bodies and brains are rapidly…

  20. Achieving Public Schools

    ERIC Educational Resources Information Center

    Abowitz, Kathleen Knight

    2011-01-01

    Public schools are functionally provided through structural arrangements such as government funding, but public schools are achieved in substance, in part, through local governance. In this essay, Kathleen Knight Abowitz explains the bifocal nature of achieving public schools; that is, that schools are both subject to the unitary Public compact of…

  1. Optical resolution of rotenoids

    USGS Publications Warehouse

    Abidi, S.L.

    1987-01-01

    Optical resolution of selected rotenoids containing 1-3 asymmetric centers in dihydrobenzopyranofuroben-zopyranone and dihydrobisbenzopyranopyranone series has been achieved on two chiral high-performance liquid chromatographic (hplc) stationary phases. In most cases, the absolute stereochemistry at the cis-B/C ring junction of the rotenoidal antipodes can be related to their elution order. Generally, the 6aα,12aα-enantiomers were more strongly retained by the chiral substrate than their corresponding optical antipodes. The elution-configuration relationship provides potential utility for predicting the absolute configuration of related rotenoidal compounds. Chiral phase hplc on amino-acid-bonded-silica yielded results explicable in terms of Pirkle's bonding schemes for chiral recognition. Resolution data for 12a-hydroxy-, 12a-methoxy-, and 12-hydroxyiminorotenoids further corroborate the mechanistic rationale, and demonstrate that nonpolar π-π interactions appeared to be important for enantiomeric separation on helic poly-triphenylmethylacryl-ate-silica (CPOT). In the latter system, steric effects and conformational factors in association with the modification of E-ring structures might play significant roles in the chiral separation process in view of the reversal to the elution order observed for all methoxylated rotenoids and elliptone derivatives including the parent deguelin. The unique separability (α = 1.44) of 12a-hydroxyelliptone on CPOT was suggestive of structural effects of the 5-side chain on the resolution of the rotenoids having a five-membered-E-ring. The results obtained with two different types of chiral phases are complementary and useful for optical resolution of a wide variety of natural and synthetic rotenoidal compounds.

  2. Design Study of a Whole-Body PET Scanner with Improved Spatial and Timing Resolution

    PubMed Central

    Surti, S.; Shore, Adam R.; Karp, Joel S.

    2013-01-01

    Current state-of-art whole-body PET scanners achieve a system spatial resolution of 4–5 mm with limited sensitivity. Since the reconstructed spatial resolution and image quality are limited by the count statistics, there has not been a significant push for developing higher resolution whole-body PET scanners. Our goal in this study is to investigate the impact of improved spatial resolution together with time-of-flight (TOF) capability on lesion uptake estimation and lesion detectability, two important tasks in whole-body oncologic studies. The broader goal of this project is the development of a new state-of-art TOF PET scanner operating within an MRI while pushing the technology in PET system design. We performed Monte Carlo simulations to test the effects of crystal size (4 mm and 2.6 mm wide crystals), TOF timing resolution (300ps and 600ps), and 2-level depth-of-interaction (DOI) capability. Spatial resolution was calculated by simulating point sources in air at multiple positions. Results show that smaller crystals produced improved resolution, while degradation of resolution due to parallax error could be reduced with a 2-level DOI detector. Lesion phantoms were simulated to measure the contrast recovery coefficient (CRC) and area under the LROC curve (ALROC) for 0.5 cm diameter lesions with 6:1 activity uptake relative to the background. Smaller crystals produce higher CRC, leading to increased ALROC values or a reduction in scan time. Improved timing resolution provides faster CRC convergence and once again leads to an increase in ALROC value or reduced scan time. Based on our choice of timing resolution and crystal size, improved timing resolution (300ps) with larger crystals (4 mm wide) has similar ALROC as smaller crystals (2.6 mm wide) with 600ps timing resolution. A 2-level DOI measurement provides some CRC and ALROC improvement for lesions further away from the center, leading to a more uniform performance within the imaging field-of-view (FOV

  3. Visual Cues for Enhancing Depth Perception.

    ERIC Educational Resources Information Center

    O'Donnell, L. M.; Smith, A. J.

    1994-01-01

    This article describes the physiological mechanisms involved in three-dimensional depth perception and presents a variety of distance and depth cues and strategies for detecting and estimating curbs and steps for individuals with impaired vision. (Author/DB)

  4. High resolution autofocus for spatial temporal biomedical research

    NASA Astrophysics Data System (ADS)

    Li, Sihong; Cui, Xiaodong; Huang, Wei

    2013-11-01

    Maintaining focus has been a critical but challenging issue in optical microscopy, particularly for microscopic imaging systems currently used in biomedical research. During live cell imaging, environmental temperature fluctuations and other factors contribute to the unavoidable focus drift. For single molecular imaging and super resolution, focus drift can be significant even over short durations. The current commercial and experimental solutions are either optically complicated, expensive, or with limited axial resolution. Here, we present a simple autofocus solution based on low cost solid state laser and imaging sensor. By improving the optical train design and using real-time data analysis, improvement in axial resolution by approximately two orders of magnitudes over the focal depth of microscope objectives can be achieved. This solution has been tested for prolonged live cell imaging for fast ramping up in environmental chamber temperature and large daily swing in room temperature. In addition, this system can be used to spatial-temporally measure the surface for three-dimensional cell culture and tissue engineering, with flexibility that exceeds commercially available systems.

  5. Objective, comparative assessment of the penetration depth of temporal-focusing microscopy for imaging various organs

    NASA Astrophysics Data System (ADS)

    Rowlands, Christopher J.; Bruns, Oliver T.; Bawendi, Moungi G.; So, Peter T. C.

    2015-06-01

    Temporal focusing is a technique for performing axially resolved widefield multiphoton microscopy with a large field of view. Despite significant advantages over conventional point-scanning multiphoton microscopy in terms of imaging speed, the need to collect the whole image simultaneously means that it is expected to achieve a lower penetration depth in common biological samples compared to point-scanning. We assess the penetration depth using a rigorous objective criterion based on the modulation transfer function, comparing it to point-scanning multiphoton microscopy. Measurements are performed in a variety of mouse organs in order to provide practical guidance as to the achievable penetration depth for both imaging techniques. It is found that two-photon scanning microscopy has approximately twice the penetration depth of temporal-focusing microscopy, and that penetration depth is organ-specific; the heart has the lowest penetration depth, followed by the liver, lungs, and kidneys, then the spleen, and finally white adipose tissue.

  6. Uterine caliper and depth gauge

    DOEpatents

    King, Loyd L.; Wheeler, Robert G.; Fish, Thomas M.

    1977-01-01

    A uterine caliper and sound consisting of an elongated body having outwardly biased resilient caliper wings and a spring-loaded slidable cervical stop. A slide on the body is operatively connected to the wings by a monofilament and operates with respect to a first scale on the body as a width indicator. A rod extending longitudinally on the body is connected to the cervical stop and cooperates with a second scale on the body as a depth indicator. The instrument can be positioned to measure the distance from the outer cervical ostium to the fundus, as read on said second scale. The wings may be allowed to open by moving the slide, and when the wings engage the utero-tubal junctions, the width may be read on said first scale. By adjustment of the caliper wings the instrument may be retracted until the resistance of the inner ostium of the cervix is felt, enabling the length of the cervical canal to be read directly by the position of the longitudinal indicator rod with respect to said second scale. The instrument may be employed to measure the width of the uterine cavity at any position between the inner ostium of the cervix and the fundus.

  7. Optical coherence microscopy in 1700 nm spectral band for high-resolution label-free deep-tissue imaging.

    PubMed

    Yamanaka, Masahito; Teranishi, Tatsuhiro; Kawagoe, Hiroyuki; Nishizawa, Norihiko

    2016-01-01

    Optical coherence microscopy (OCM) is a label-free, high-resolution, three-dimensional (3D) imaging technique based on optical coherence tomography (OCT) and confocal microscopy. Here, we report that the 1700-nm spectral band has the great potential to improve the imaging depth in high-resolution OCM imaging of animal tissues. Recent studies to improve the imaging depth in OCT revealed that the 1700-nm spectral band is a promising choice for imaging turbid scattering tissues due to the low attenuation of light in the wavelength region. In this study, we developed high-resolution OCM by using a high-power supercontinuum source in the 1700-nm spectral band, and compared the attenuation of signal-to-noise ratio between the 1700-nm and 1300-nm OCM imaging of a mouse brain under the condition of the same sensitivity. The comparison clearly showed that the 1700-nm OCM provides larger imaging depth than the 1300-nm OCM. In this 1700-nm OCM, the lateral resolution of 1.3 μm and the axial resolution of 2.8 μm, when a refractive index was assumed to be 1.38, was achieved. PMID:27546517

  8. Optical coherence microscopy in 1700 nm spectral band for high-resolution label-free deep-tissue imaging

    NASA Astrophysics Data System (ADS)

    Yamanaka, Masahito; Teranishi, Tatsuhiro; Kawagoe, Hiroyuki; Nishizawa, Norihiko

    2016-08-01

    Optical coherence microscopy (OCM) is a label-free, high-resolution, three-dimensional (3D) imaging technique based on optical coherence tomography (OCT) and confocal microscopy. Here, we report that the 1700-nm spectral band has the great potential to improve the imaging depth in high-resolution OCM imaging of animal tissues. Recent studies to improve the imaging depth in OCT revealed that the 1700-nm spectral band is a promising choice for imaging turbid scattering tissues due to the low attenuation of light in the wavelength region. In this study, we developed high-resolution OCM by using a high-power supercontinuum source in the 1700-nm spectral band, and compared the attenuation of signal-to-noise ratio between the 1700-nm and 1300-nm OCM imaging of a mouse brain under the condition of the same sensitivity. The comparison clearly showed that the 1700-nm OCM provides larger imaging depth than the 1300-nm OCM. In this 1700-nm OCM, the lateral resolution of 1.3 μm and the axial resolution of 2.8 μm, when a refractive index was assumed to be 1.38, was achieved.

  9. Optical coherence microscopy in 1700 nm spectral band for high-resolution label-free deep-tissue imaging

    PubMed Central

    Yamanaka, Masahito; Teranishi, Tatsuhiro; Kawagoe, Hiroyuki; Nishizawa, Norihiko

    2016-01-01

    Optical coherence microscopy (OCM) is a label-free, high-resolution, three-dimensional (3D) imaging technique based on optical coherence tomography (OCT) and confocal microscopy. Here, we report that the 1700-nm spectral band has the great potential to improve the imaging depth in high-resolution OCM imaging of animal tissues. Recent studies to improve the imaging depth in OCT revealed that the 1700-nm spectral band is a promising choice for imaging turbid scattering tissues due to the low attenuation of light in the wavelength region. In this study, we developed high-resolution OCM by using a high-power supercontinuum source in the 1700-nm spectral band, and compared the attenuation of signal-to-noise ratio between the 1700-nm and 1300-nm OCM imaging of a mouse brain under the condition of the same sensitivity. The comparison clearly showed that the 1700-nm OCM provides larger imaging depth than the 1300-nm OCM. In this 1700-nm OCM, the lateral resolution of 1.3 μm and the axial resolution of 2.8 μm, when a refractive index was assumed to be 1.38, was achieved. PMID:27546517

  10. Student Achievement and Motivation

    ERIC Educational Resources Information Center

    Flammer, Gordon H.; Mecham, Robert C.

    1974-01-01

    Compares the lecture and self-paced methods of instruction on the basis of student motivation and achieveme nt, comparing motivating and demotivating factors in each, and their potential for motivation and achievement. (Authors/JR)

  11. Depth enhanced and content aware video stabilization

    NASA Astrophysics Data System (ADS)

    Lindner, A.; Atanassov, K.; Goma, S.

    2015-03-01

    We propose a system that uses depth information for video stabilization. The system uses 2D-homographies as frame pair transforms that are estimated with keypoints at the depth of interest. This makes the estimation more robust as the points lie on a plane. The depth of interest can be determined automatically from the depth histogram, inferred from user input such as tap-to-focus, or selected by the user; i.e., tap-to-stabilize. The proposed system can stabilize videos on the fly in a single pass and is especially suited for mobile phones with multiple cameras that can compute depth maps automatically during image acquisition.

  12. Is visual short-term memory depthful?

    PubMed

    Reeves, Adam; Lei, Quan

    2014-03-01

    Does visual short-term memory (VSTM) depend on depth, as it might be if information was stored in more than one depth layer? Depth is critical in natural viewing and might be expected to affect retention, but whether this is so is currently unknown. Cued partial reports of letter arrays (Sperling, 1960) were measured up to 700 ms after display termination. Adding stereoscopic depth hardly affected VSTM capacity or decay inferred from total errors. The pattern of transposition errors (letters reported from an uncued row) was almost independent of depth and cue delay. We conclude that VSTM is effectively two-dimensional. PMID:24491386

  13. Endoscopic ultrahigh-resolution OCT for in vivo imaging colon disease model mice

    NASA Astrophysics Data System (ADS)

    Tumlinson, Alexandre R.; McNally, James; Unterhuber, Angelika; Hermann, Boris; Sattmann, Harald; Hariri, Lida; Drexler, Wolfgang; Barton, Jennifer K.

    2005-04-01

    Mouse models are increasingly important for studying human GI pathology. OCT provides minimally invasive, cross-sectional images that indicate the thickness and scattering density of underlying tissue. We have developed endoscopic ultrahigh resolution OCT (UHR-OCT) for the purpose of in vivo imaging in mouse colon. The reduced scale of the mouse colon makes tissue light penetration much less problematic, and high resolution acutely necessary. Higher lateral resolution requires a departure from the traditional cemented GRIN lens design. We support the need for better chromatic aberration than can be achieved by a GRIN lens using commercial raytracing software. We have designed and built a 2mm diameter endoscopic UHR-OCT system achromatized for 770-1020nm for use with a Titanium:sapphire laser with 260 nm bandwidth at full-width-half-maximum centered at 800 nm while achieving a 4.4um lateral spot dimension at focus. A pair of KZFSN5/SFPL53 doublets provides excellent primary and secondary color correction to maintain wide bandwidth through the imaging depth. A slight deviation from normal beam exit angle suppresses collection of the strong back reflection at the exit window surface. The novel design endoscope was built and characterized for through focus bandwidth, axial resolution, signal to noise, and lateral spot dimension. Performance is demonstrated on a variety of ex vivo tissues and in situ mouse colon. Ultrahigh-resolution images of mouse tissue enable the visualization of microscopic features, including crypts that have previously been observed with standard resolution OCT in humans but were too small to see in mouse tissue. Resolution near the cellular level is potentially capable of identifying abnormal crypt formation and dysplastic cellular organization.

  14. Performance Metrics for Depth-based Signal Separation Using Deep Vertical Line Arrays

    NASA Astrophysics Data System (ADS)

    Boyle, John K.

    Vertical line arrays (VLAs) deployed below the critical depth in the deep ocean can exploit reliable acoustic path (RAP) propagation, which provides low transmission loss (TL) for targets at moderate ranges, and increased TL for distant interferers. However, sound from nearby surface interferers also undergoes RAP propagation, and without horizontal aperture, a VLA cannot separate these interferers from submerged targets. A recent publication by McCargar and Zurk (2013) addressed this issue, presenting a transform-based method for passive, depth-based separation of signals received on deep VLAs based on the depth-dependent modulation caused by the interference between the direct and surface-reflected acoustic arrivals. This thesis expands on that work by quantifying the transform-based depth estimation method performance in terms of the resolution and ambiguity in the depth estimate. Then, the depth discrimination performance is quantified in terms of the number of VLA elements.

  15. Classified-edge guided depth resampling for multi-view coding

    NASA Astrophysics Data System (ADS)

    Lu, Yu; Zhou, Yang; Chen, Hua-hua

    2016-01-01

    A new depth resampling for multi-view coding is proposed in this paper. At first, the depth video is downsampled by median filtering before encoding. After decoding, the classified edges, including credible edge and probable edge from the aligned texture image and the depth image, are interpolated by the selected diagonal pair, whose intensity difference is the minimum among four diagonal pairs around edge pixel. According to different category of edge, the intensity difference is measured by either real depth or percentage depth without any parameter setting. Finally, the resampled depth video and the decoded full-resolution texture video are synthesized into virtual views for the performance evaluation. Experiments on the platform of multi-view high efficiency video coding (HEVC) demonstrate that the proposed method is superior to the contrastive methods in terms of visual quality and rate distortion (RD) performance.

  16. Measuring stress variation with depth using Barkhausen signals

    NASA Astrophysics Data System (ADS)

    Kypris, O.; Nlebedim, I. C.; Jiles, D. C.

    2016-06-01

    Magnetic Barkhausen noise analysis (BNA) is an established technique for the characterization of stress in ferromagnetic materials. An important application is the evaluation of residual stress in aerospace components, where shot-peening is used to strengthen the part by inducing compressive residual stresses on its surface. However, the evaluation of the resulting stress-depth gradients cannot be achieved by conventional BNA methods, where signals are interpreted in the time domain. The immediate alternative of using x-ray diffraction stress analysis is less than ideal, as the use of electropolishing to remove surface layers renders the part useless after inspection. Thus, a need for advancing the current BNA techniques prevails. In this work, it is shown how a parametric model for the frequency spectrum of Barkhausen emissions can be used to detect variations of stress along depth in ferromagnetic materials. Proof of concept is demonstrated by inducing linear stress-depth gradients using four-point bending, and fitting the model to the frequency spectra of measured Barkhausen signals, using a simulated annealing algorithm to extract the model parameters. Validation of our model suggests that in bulk samples the Barkhausen frequency spectrum can be expressed by a multi-exponential function with a dependence on stress and depth. One practical application of this spectroscopy method is the non-destructive evaluation of residual stress-depth profiles in aerospace components, thus helping to prevent catastrophic failures.

  17. Development of a large-angle pinhole gamma camera with depth-of-interaction capability for small animal imaging

    NASA Astrophysics Data System (ADS)

    Baek, C.-H.; An, S. J.; Kim, H.-I.; Choi, Y.; Chung, Y. H.

    2012-01-01

    A large-angle gamma camera was developed for imaging small animal models used in medical and biological research. The simulation study shows that a large field of view (FOV) system provides higher sensitivity with respect to a typical pinhole gamma cameras by reducing the distance between the pinhole and the object. However, this gamma camera suffers from the degradation of the spatial resolution at the periphery region due to parallax error by obliquely incident photons. We propose a new method to measure the depth of interaction (DOI) using three layers of monolithic scintillators to reduce the parallax error. The detector module consists of three layers of monolithic CsI(Tl) crystals with dimensions of 50.0 × 50.0 × 2.0 mm3, a Hamamatsu H8500 PSPMT and a large-angle pinhole collimator with an acceptance angle of 120°. The 3-dimensional event positions were determined by the maximum-likelihood position-estimation (MLPE) algorithm and the pre-generated look up table (LUT). The spatial resolution (FWHM) of a Co-57 point-like source was measured at different source position with the conventional method (Anger logic) and with DOI information. We proved that high sensitivity can be achieved without degradation of spatial resolution using a large-angle pinhole gamma camera: this system can be used as a small animal imaging tool.

  18. Estimation of Sea Ice Thickness Distributions through the Combination of Snow Depth and Satellite Laser Altimetry Data

    NASA Technical Reports Server (NTRS)

    Kurtz, Nathan T.; Markus, Thorsten; Cavalieri, Donald J.; Sparling, Lynn C.; Krabill, William B.; Gasiewski, Albin J.; Sonntag, John G.

    2009-01-01

    Combinations of sea ice freeboard and snow depth measurements from satellite data have the potential to provide a means to derive global sea ice thickness values. However, large differences in spatial coverage and resolution between the measurements lead to uncertainties when combining the data. High resolution airborne laser altimeter retrievals of snow-ice freeboard and passive microwave retrievals of snow depth taken in March 2006 provide insight into the spatial variability of these quantities as well as optimal methods for combining high resolution satellite altimeter measurements with low resolution snow depth data. The aircraft measurements show a relationship between freeboard and snow depth for thin ice allowing the development of a method for estimating sea ice thickness from satellite laser altimetry data at their full spatial resolution. This method is used to estimate snow and ice thicknesses for the Arctic basin through the combination of freeboard data from ICESat, snow depth data over first-year ice from AMSR-E, and snow depth over multiyear ice from climatological data. Due to the non-linear dependence of heat flux on ice thickness, the impact on heat flux calculations when maintaining the full resolution of the ICESat data for ice thickness estimates is explored for typical winter conditions. Calculations of the basin-wide mean heat flux and ice growth rate using snow and ice thickness values at the 70 m spatial resolution of ICESat are found to be approximately one-third higher than those calculated from 25 km mean ice thickness values.

  19. Ultrasonic bath depth control and regulation in single cell recordings.

    PubMed

    Duong Dinh, Thien An; Jüngling, Eberhard; Strotmann, Karl-Heinz; Westhofen, Martin; Lückhoff, Andreas

    2006-09-01

    Control of the bath depth is critical in many applications of the patch-clamp technique, particularly when the capacitance of cells is determined to assess secretion or transmitter release or in studies of ion currents sensitive to small changes in the hydrostatic pressure. We describe an inexpensive technique for tight control of the bath depth with the aid of a commercially available ultrasound sensor. The sensor continuously determines changes in the distance to the bath surface with a resolution of about 10 mum. The signal from the sensor is digitized in a microcontroller card and used to send on or off signals at 100 Hz to a peristaltic pump that removes volume from the bath. The inflow into the bath can be realized in a versatile way. The capacitance of Sylgard-coated patch-clamp glass electrodes, demonstrated to be extremely sensitive to small changes in the area moistened by bath solution, is constant within the noise level of +/-3 fF when immersed into a depth-controlled bath, even during exchange of the bath medium. Thus, when small changes in the cell capacitance are measured in patch-clamp experiments, errors due to alterations in the pipette capacitance caused by bath depth fluctuations are eliminated.

  20. Feasibility of depth profiling of Zn-based coatings by laser ablation inductively coupled plasma optical emission and mass spectrometry using infrared Nd:YAG and ArF* lasers

    NASA Astrophysics Data System (ADS)

    Hrdlička, Aleš; Otruba, Vítĕzslav; Novotný, Karel; Günther, Detlef; Kanický, Viktor

    2005-03-01

    The feasibility of depth profiling of zinc-coated iron sheets by laser ablation (LA) was studied using an Nd:YAG laser (1064 nm) with inductively coupled plasma optical emission spectrometry (ICP-OES), and an excimer ArF* laser (193 nm) with a beam homogenizer. The latter was coupled to an ICP with mass spectrometry (ICP-MS). Fixed-spot ablation was applied. Both LA systems were capable of providing depth profiles that approach the profiles obtained by glow discharge optical emission spectroscopy (GD-OES) and electron probe X-ray microanalysis (EPXMA). For Nd:YAG laser an artefact consisting of zinc depth profile signal tailing appeared, enlarging thus erroneously diffusional coating-substrate interface profile. However, the ArF* system partially reduced but not suppressed that phenomenon. For both LA systems the Fe signal from the substrate increased with depth as expected and reached a plateau. The depth resolution (depth range corresponding to 84%-16% change in the full signal) achieved was several micrometers. Ablation rate was found to depend on ablation spot area at constant irradiance. Consequently, ablated volume per shot dependence on pulse energy exhibits deviation from linear course.

  1. Rural Family Life Style and Sons' School Achievement.

    ERIC Educational Resources Information Center

    Mueller, B. Jeanne

    This study was designed: (1) to examine in depth family-related variables in 30 rural working-class families in order to determine whether there are certain life-style differences between those whose sons achieve at or above grade level and those whose sons' achievements fall below grade level; and (2) to gather information on how early boys begin…

  2. Extended depth of focus for transmission x-ray microscope.

    PubMed

    Liu, Yijin; Wang, Junyue; Hong, Youli; Wang, Zhili; Zhang, Kai; Williams, Phillip A; Zhu, Peiping; Andrews, Joy C; Pianetta, Piero; Wu, Ziyu

    2012-09-01

    A fast discrete curvelet transform based focus-stacking algorithm for extending the depth of focus of a transmission x-ray microscope (TXM) is presented. By analyzing an image stack of a sample taken in a Z-scan, a fully in-focus image can be generated by the proposed scheme. With the extended depth of focus, it is possible to obtain 3D structural information over a large volume at nanometer resolution. The focus-stacking method has been demonstrated using a dataset taken with a laboratory x-ray source based TXM system. The possibility and limitations of generalizing this method to a synchrotron based TXM are also discussed. We expect the proposed method to be of important impact in 3D x-ray microscopy. PMID:22940998

  3. Towards Depth-Resolved Optical Imaging of Cardiac Electrical Activity.

    PubMed

    Walton, Richard D; Bernus, Olivier

    2015-01-01

    The spatiotemporal dynamics of arrhythmias are likely to be complex three-dimensional phenomena. Yet, the lack of high-resolution three-dimensional imaging techniques, both in the clinic and the experimental lab, limits our ability to better understand the mechanisms of such arrhythmias. Optical mapping using voltage-sensitive dyes is a widely used tool in experimental electrophysiology. It has been known for decades that even in its most basic application, epi-fluorescence, the optical signal contains information from within a certain intramural volume. Understanding of this fundamental property of optical signals has paved the way towards novel three-dimensional optical imaging techniques. Here, we review our current understanding of the three-dimensional nature of optical signals; how penetration depths of cardiac optical imaging can be improved by using novel imaging modalities and finally, we highlight new techniques inspired from optical tomography and aiming at full depth-resolved optical mapping of cardiac electrical activity. PMID:26238062

  4. Temperature dependence of penetration depth in thin film niobium

    NASA Technical Reports Server (NTRS)

    More, N.; Muhlfelder, B.; Lockhart, J.

    1989-01-01

    A novel technique is presented which should allow precise determination of the temperature dependence of the inductance, and hence of the penetration depth, of superconducting niobium thin-film structures. Four niobium thin-film stripline inductors are arranged in a bridge configuration, and inductance differences are measured using a potentiometric technique with a SQUID (superconducting quantum interference device) as the null detector. Numerical simulations of the stripline inductances are presented which allow the performance of the measurement technique to be evaluated. The prediction of the two-fluid model for the penetration-depth temperature dependence is given for reduced temperatures of 0.3 to 0.9. The experimental apparatus and its resolution and accuracy are discussed.

  5. Prescription of land-surface boundary conditions in GISS GCM 2: A simple method based on high-resolution vegetation data bases

    NASA Technical Reports Server (NTRS)

    Matthews, E.

    1984-01-01

    A simple method was developed for improved prescription of seasonal surface characteristics and parameterization of land-surface processes in climate models. This method, developed for the Goddard Institute for Space Studies General Circulation Model II (GISS GCM II), maintains the spatial variability of fine-resolution land-cover data while restricting to 8 the number of vegetation types handled in the model. This was achieved by: redefining the large number of vegetation classes in the 1 deg x 1 deg resolution Matthews (1983) vegetation data base as percentages of 8 simple types; deriving roughness length, field capacity, masking depth and seasonal, spectral reflectivity for the 8 types; and aggregating these surface features from the 1 deg x 1 deg resolution to coarser model resolutions, e.g., 8 deg latitude x 10 deg longitude or 4 deg latitude x 5 deg longitude.

  6. Evaluation of Advanced Bionics high resolution mode.

    PubMed

    Buechner, Andreas; Frohne-Buechner, Carolin; Gaertner, Lutz; Lesinski-Schiedat, Anke; Battmer, Rolf-Dieter; Lenarz, Thomas

    2006-07-01

    The objective of this paper is to evaluate the advantages of the Advanced Bionic high resolution mode for speech perception, through a retrospective analysis. Forty-five adult subjects were selected who had a minimum experience of three months' standard mode (mean of 10 months) before switching to high resolution mode. Speech perception was tested in standard mode immediately before fitting with high resolution mode, and again after a maximum of six months high resolution mode usage (mean of two months). A significant improvement was found, between 11 and 17%, depending on the test material. The standard mode preference does not give any indication about the improvement when switching to high resolution. Users who are converted within any study achieve a higher performance improvement than those converted in the clinical routine. This analysis proves the significant benefits of high resolution mode for users, and also indicates the need for guidelines for individual optimization of parameter settings in a high resolution mode program.

  7. Using a fixed-wing UAS to map snow depth distribution: an evaluation at peak accumulation

    NASA Astrophysics Data System (ADS)

    De Michele, Carlo; Avanzi, Francesco; Passoni, Daniele; Barzaghi, Riccardo; Pinto, Livio; Dosso, Paolo; Ghezzi, Antonio; Gianatti, Roberto; Della Vedova, Giacomo

    2016-03-01

    We investigate snow depth distribution at peak accumulation over a small Alpine area ( ˜ 0.3 km2) using photogrammetry-based surveys with a fixed-wing unmanned aerial system (UAS). These devices are growing in popularity as inexpensive alternatives to existing techniques within the field of remote sensing, but the assessment of their performance in Alpine areas to map snow depth distribution is still an open issue. Moreover, several existing attempts to map snow depth using UASs have used multi-rotor systems, since they guarantee higher stability than fixed-wing systems. We designed two field campaigns: during the first survey, performed at the beginning of the accumulation season, the digital elevation model of the ground was obtained. A second survey, at peak accumulation, enabled us to estimate the snow depth distribution as a difference with respect to the previous aerial survey. Moreover, the spatial integration of UAS snow depth measurements enabled us to estimate the snow volume accumulated over the area. On the same day, we collected 12 probe measurements of snow depth at random positions within the case study to perform a preliminary evaluation of UAS-based snow depth. Results reveal that UAS estimations of point snow depth present an average difference with reference to manual measurements equal to -0.073 m and a RMSE equal to 0.14 m. We have also explored how some basic snow depth statistics (e.g., mean, standard deviation, minima and maxima) change with sampling resolution (from 5 cm up to ˜ 100 m): for this case study, snow depth standard deviation (hence coefficient of variation) increases with decreasing cell size, but it stabilizes for resolutions smaller than 1 m. This provides a possible indication of sampling resolution in similar conditions.

  8. Exploration application of high resolution aeromagnetic surveys in the Gulf of Mexico, USA

    SciTech Connect

    Berger, Z.; Reudavey, G.

    1996-08-01

    High resolution magnetic surveys provide an excellent tool for mapping geological structures in a wide range of tectonic settings and geographical areas. The improved mapping capabilities of these surveys are achieved by: (1) Advanced high resolution data acquisition techniques including lower altitudes, tighter line spacing, and broad-band frequency retention, and (2) advanced data processing and display techniques such as depth slicing, micro-leveling and image processing. Newly acquired high resolution aeromagnetic surveys of Cameron and Vermilion areas have been recently interpreted. The results of this study can be summarized as follows: (1) The magnetic images of high frequency domain can be used to map near surface salt fastuws and growth faults. These images can also be used to define the shape of the salt diapers and assess their interaction with different fault systems. (2) Interpretation and modeling of different depth-slice images can be used to determine the thickness of different salt bodies and establish their progressive changes with depth. This technique can also be used to outline potential sedimentary basins at different depths. (3) Magnetic images of mid to low frequency domains can be used to establish the structural fabric of sub-salt terrain. The result of this study is presented with a series of posters that illustrate the inventory of salt and fault features identified on different magnetic images and their correlation with subsurface structures which are recognized with well and seismic data. Magnetic profiles and models are also being used to illustrate how the magnetic data was calibrate to the recorded travel-time of seismic data and related isochron and time structure maps.

  9. Snow Depth Mapping at a Basin-Wide Scale in the Western Arctic Using UAS Technology

    NASA Astrophysics Data System (ADS)

    de Jong, T.; Marsh, P.; Mann, P.; Walker, B.

    2015-12-01

    Assessing snow depths across the Arctic has proven to be extremely difficult due to the variability of snow depths at scales from metres to 100's of metres. New Unmanned Aerial Systems (UAS) technology provides the possibility to obtain centimeter level resolution imagery (~3cm), and to create Digital Surface Models (DSM) based on the Structure from Motion method. However, there is an ongoing need to quantify the accuracy of this method over different terrain and vegetation types across the Arctic. In this study, we used a small UAS equipped with a high resolution RGB camera to create DSMs over a 1 km2 watershed in the western Canadian Arctic during snow (end of winter) and snow-free periods. To improve the image georeferencing, 15 Ground Control Points were marked across the watershed and incorporated into the DSM processing. The summer DSM was subtracted from the snowcovered DSM to deliver snow depth measurements across the entire watershed. These snow depth measurements were validated by over 2000 snow depth measurements. This technique has the potential to improve larger scale snow depth mapping across watersheds by providing snow depth measurements at a ~3 cm . The ability of mapping both shallow snow (less than 75cm) covering much of the basin and snow patches (up to 5 m in depth) that cover less than 10% of the basin, but contain a significant portion of total basin snowcover, is important for both water resource applications, as well as for testing snow models.

  10. Bessel-beam Grueneisen relaxation photoacoustic microscopy with extended depth of field

    NASA Astrophysics Data System (ADS)

    Shi, Junhui; Wang, Lidai; Noordam, Cedric; Wang, Lihong V.

    2015-11-01

    The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction free, provides a long focal depth, but its side lobes deteriorate image quality when the Bessel beam is directly employed to excite photoacoustic (PA) signals in OR-PAM. We present a nonlinear approach based on the Grueneisen relaxation effect to suppress the side-lobe artifacts in PA imaging. This method extends the focal depth of OR-PAM and speeds up volumetric imaging. We experimentally demonstrated a 1-mm focal depth with a 7-μm lateral resolution and volumetrically imaged a carbon fiber and red blood cell samples.

  11. Comparison of Cirrus height and optical depth derived from satellite and aircraft measurements

    SciTech Connect

    Kastner, M.; Kriebel, K.T.; Meerkoetter, R.; Renger, W.; Ruppersberg, G.H.; Wendling, P. )

    1993-10-01

    During the International Cirrus Experiment (ICE'89) simultaneous measurements of cirrus cloud-top height and optical depth by satellite and aircraft have been taken. Data from the Advanced Very High Resolution Radiometer (AVHRR) onboard the NOAA polar-orbiting meteorological satellite system have been used together with the algorithm package AVHRR processing scheme over clouds, land and ocean (APOLLO) to derive optical depth. NOAA High-Resolution Infrared Radiation Sounder (HIRS) data have been used together with a bispectral technique to derive cloud-top height. Also, the optical depth of some contrails could be estimated. Airborne measurements have been performed simultaneously by using the Airborne Lidar Experiment (ALEX), a backscatter lidar. Comparison of satellite data with airborne data showed agreement of the top heights to about 500 m and of the optical depths to about 30%. These uncertainties are within the limits obtained from error estimates. 34 refs., 8 figs.

  12. High resolution lunar mascon three dimensional density structure revealed by GRAIL gravity

    NASA Astrophysics Data System (ADS)

    Jianguo, Yan; Yi, Zhang

    2016-07-01

    In the history of the moon exploration, the most amazing achievement is that some mass concentrated areas were found on the near side of the moon1, 2. These mass concentrated areas, which are referred to mascons, are usually covered with a positive gravity anomaly peak, and surrounded by negative gravity anomalies with low geographical elevation1-7. Here we proposed a gravity inverse method including geological constraint to obtain density structure of the lunar mascons. The method was implemented in spherical coordinates and validated with simulation test. Using this method we obtained high resolution density anomaly structure of lunar near side maria mascons basins and far side highland mascons. The high resolution depth information and density anomalies structure of the lunar mascons are presented for the first time. By comparing the near side maria mascons with far side mascons, we found all the mascons have an annulus density structures in their shallow stratums; the mascon depth information also indicates that the mascon depth on lunar far side is much deeper than that on the near side. These results indicate various origination mechanism between nearside and farside mascons.

  13. Interactively variable isotropic resolution in computed tomography

    NASA Astrophysics Data System (ADS)

    Lapp, Robert M.; Kyriakou, Yiannis; Kachelrieß, Marc; Wilharm, Sylvia; Kalender, Willi A.

    2008-05-01

    An individual balancing between spatial resolution and image noise is necessary to fulfil the diagnostic requirements in medical CT imaging. In order to change influencing parameters, such as reconstruction kernel or effective slice thickness, additional raw-data-dependent image reconstructions have to be performed. Therefore, the noise versus resolution trade-off is time consuming and not interactively applicable. Furthermore, isotropic resolution, expressed by an equivalent point spread function (PSF) in every spatial direction, is important for the undistorted visualization and quantitative evaluation of small structures independent of the viewing plane. Theoretically, isotropic resolution can be obtained by matching the in-plane and through-plane resolution with the aforementioned parameters. Practically, however, the user is not assisted in doing so by current reconstruction systems and therefore isotropic resolution is not commonly achieved, in particular not at the desired resolution level. In this paper, an integrated approach is presented for equalizing the in-plane and through-plane spatial resolution by image filtering. The required filter kernels are calculated from previously measured PSFs in x/y- and z-direction. The concepts derived are combined with a variable resolution filtering technique. Both approaches are independent of CT raw data and operate only on reconstructed images which allows for their application in real time. Thereby, the aim of interactively variable, isotropic resolution is achieved. Results were evaluated quantitatively by measuring PSFs and image noise, and qualitatively by comparing the images to direct reconstructions regarded as the gold standard. Filtered images matched direct reconstructions with arbitrary reconstruction kernels with standard deviations in difference images of typically between 1 and 17 HU. Isotropic resolution was achieved within 5% of the selected resolution level. Processing times of 20-100 ms per frame

  14. Student academic achievement in college chemistry

    NASA Astrophysics Data System (ADS)

    Tabibzadeh, Kiana S.

    General Chemistry is required for variety of baccalaureate degrees, including all medical related fields, engineering, and science majors. Depending on the institution, the prerequisite requirement for college level General Chemistry varies. The success rate for this course is low. The purpose of this study is to examine the factors influencing student academic achievement and retention in General Chemistry at the college level. In this study student achievement is defined by those students who earned grades of "C" or better. The dissertation contains in-depth studies on influence of Intermediate Algebra as a prerequisite compared to Fundamental Chemistry for student academic achievement and student retention in college General Chemistry. In addition the study examined the extent and manner in which student self-efficacy influences student academic achievement in college level General Chemistry. The sample for this part of the study is 144 students enrolled in first semester college level General Chemistry. Student surveys determined student self-efficacy level. The statistical analyses of study demonstrated that Fundamental Chemistry is a better prerequisite for student academic achievement and student retention. The study also found that student self-efficacy has no influence on student academic achievement. The significance of this study will be to provide data for the purpose of establishing a uniform and most suitable prerequisite for college level General Chemistry. Finally the variables identified to influence student academic achievement and enhance student retention will support educators' mission to maximize the students' ability to complete their educational goal at institutions of higher education.

  15. Ultra-high resolution polarization-sensitive optical coherence microscopy for brain imaging at 6 um, 3.4 um and 1.3 um resolution (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wang, Hui; Akkin, Taner; Magnain, Caroline V.; Yaseen, Mohammad A.; Cramer, Avilash; Wang, Ruopeng; Sakadžic, Sava; Boas, David A.

    2016-03-01

    Neuroanatomical pathways form the basis for functional activity of brain circuits. In the past, we developed a polarization-sensitive optical coherence tomography with serial scanning to achieve large-scale brain imaging. The system was able to visualize 3D fiber tracts of ~20 um in diameter. To investigate the neuroanatomical pathways at finer scales, we have now built a polarization-maintaining fiber based ultra-high resolution polarization-sensitive optical coherence microscope (PS-OCM) at 1300 nm. The PS-OCM has an axial resolution of 3.5 um in tissue. The detection setup consists of two spectrometers, acquiring spectral interference on orthogonal polarization channels. With a single measurement, the setup generates four contrasts: reflectivity, cross-polarization, retardance and optic axis orientation. To investigate the capability of PS-OCM at different resolutions, we used three microscope objectives that yield lateral resolutions of 6.0 um, 3.4 um and 1.3 um. Blocks of formalin fixed mouse brain and human brain were scanned. The cross-polarization and retardance images clearly depict the neuronal fiber structures, which are comparable with that generated by the maximum projection of volumetric reflectivity data. The optic axis orientation quantifies the in-plane fiber orientation. With the lateral resolution of 1.3 um, the retardance contrast is weak in white matter due to the shallow depth of focus. Overall, the ultra-high resolution PS-OCM provides a new tool to reveal neuroanatomical maps in the brain at cellular resolution.

  16. Mechanisms and depths of atlantic transform earthquakes

    NASA Technical Reports Server (NTRS)

    Engeln, J. F.; Wiens, D. A.; Stein, S.

    1986-01-01

    Mechanisms and depths of 40 earthquakes on major transforms along the Mid-Atlantic Ridge are studied in order to identify events that deviate from the transform-parallel strike-slip motion. Long and short period waves and Rayleigh wave spectral amplitudes are used to analyze focal mechanisms, depths, source time functions, and seismic moments of earthquakes. The relationship between centroid depths and transform thermal structures is examined. The data reveal that transform earthquake centroid depths occur above the predicted 400 C isotherms and the oceanic intraplate depths extend to the 750 C isotherm. Slip rates inferred from seismic moment releases are compared to those predicted by plate motions and good correlation is detected. The difference in the centroid depths of transform and interplate seismicity indicates transforms are either weaker or higher temperatures than expected.

  17. Repeated 1-cm Resolution Topographic and 2.5-mm Resolution Photomosiac Surveys of Benthic Communities and Fine Scale Bedforms in Monterey Canyon

    NASA Astrophysics Data System (ADS)

    Caress, D. W.; Hobson, B.; Thomas, H. J.; Henthorn, R.; Martin, E. J.; Bird, L.; Risi, M.; Troni, G.; Paull, C. K.; Rock, S.; Padial, J. A.; Hammond, M. M.

    2014-12-01

    The Monterey Bay Aquarium Research Institute has developed a low altitude, ROV-based seafloor mapping system that combines lidar laser ranging, multibeam sonar, and stereo photographic imagery. When operated at a 3-m altitude, this system maps seafloor topography with a 1-cm lateral resolution and simultaneously collects 2.5-mm resolution color photography. We have twice mapped an 80-m by 80-m area of a chemosynthetic clam community located at 2850-m depth in the Monterey Canyon axis. Both the topography and the photomosaics resolve changes in the clam community over a six-month interval. Many individual animals have moved, and tracks of those animals are visible in the lidar topography. No other changes in the seafloor at this site can be discerned. We have also performed single surveys of bedforms and scours at both 1850-m and 2850-m depths in Monterey Canyon. The highest resolution bathymetry data are collected using a 3DatDepth SL1 lidar laser scanner. This system has a 30° field of view and ranges continuously, achieving a 1 cm sounding spacing at a 3 m altitude and 0.3 m/s speed. Bathymetry data are also collected using a 400-kHz Reson 7125 multibeam sonar. This configuration produces 512 beams across a 135° wide swath; each beam has a 0.5° acrosstrack by 1.0° alongtrack angular width. At a 3-m altitude, the nadir beams have a 2.5 cm acrosstrack and 5 cm alongtrack footprint. Dual Prosilica GX1920 2.4 Mpixel color cameras provide color stereo photography of the seafloor. Illumination is provided by dual xenon strobes. The camera housings have been fitted with corrective optics achieving a 90° field of view with less than 1% distortion. At a 3-m altitude the raw image pixels have a 2.5 mm resolution. Position and attitude data are provided by a Kearfott SeaDevil Inertial Navigation System (INS) integrated with a 300 kHz Teledyne RD Instruments Doppler velocity log (DVL). A separate Paroscientific pressure sensor is mounted adjacent to the INS. The INS

  18. In-line three-dimensional holography of nanocrystalline objects at atomic resolution.

    PubMed

    Chen, F-R; Van Dyck, D; Kisielowski, C

    2016-01-01

    Resolution and sensitivity of the latest generation aberration-corrected transmission electron microscopes allow the vast majority of single atoms to be imaged with sub-Ångstrom resolution and their locations determined in an image plane with a precision that exceeds the 1.9-pm wavelength of 300 kV electrons. Such unprecedented performance allows expansion of electron microscopic investigations with atomic resolution into the third dimension. Here we report a general tomographic method to recover the three-dimensional shape of a crystalline particle from high-resolution images of a single projection without the need for sample rotation. The method is compatible with low dose rate electron microscopy, which improves on signal quality, while minimizing electron beam-induced structure modifications even for small particles or surfaces. We apply it to germanium, gold and magnesium oxide particles, and achieve a depth resolution of 1-2 Å, which is smaller than inter-atomic distances. PMID:26887849

  19. Synchronous scanning of reference mirror and objective lens for high-resolution full-field interferometry

    NASA Astrophysics Data System (ADS)

    Kashiwagi, Ken; Kasuya, Yosuke; Kojima, Shuto; Kurokawa, Takashi

    2015-03-01

    We realized a long-scanning-range and high-resolution interferometry in a time-domain full-field microscopic scheme by adopting a simple configuration. A reference mirror was synchronously scanned with an objective lens, which was installed in a common path, to prevent lateral resolution degradation due to defocus at the mirror. High axial resolution was obtained using a broadband supercontinuum (SC) generated by a 1.55 µm pump. The SC was generated by propagating a femtosecond pulse at 1.55 µm through a highly nonlinear dispersion shifted fiber with a small dispersion slope. We designed and constructed an interferometer carefully to utilize the entire bandwidth. The broad bandwidth of the interferometer achieved an axial resolution of 2.50 µm in air. The synchronous scanning maintained a lateral resolution longer than 1 mm. The system successfully yielded a cross-sectional image of two layers of scotch tape along the 400-µm-depth and 90-nm-step surface profiles.

  20. In-line three-dimensional holography of nanocrystalline objects at atomic resolution

    PubMed Central

    Chen, F.-R.; Van Dyck, D.; Kisielowski, C.

    2016-01-01

    Resolution and sensitivity of the latest generation aberration-corrected transmission electron microscopes allow the vast majority of single atoms to be imaged with sub-Ångstrom resolution and their locations determined in an image plane with a precision that exceeds the 1.9-pm wavelength of 300 kV electrons. Such unprecedented performance allows expansion of electron microscopic investigations with atomic resolution into the third dimension. Here we report a general tomographic method to recover the three-dimensional shape of a crystalline particle from high-resolution images of a single projection without the need for sample rotation. The method is compatible with low dose rate electron microscopy, which improves on signal quality, while minimizing electron beam-induced structure modifications even for small particles or surfaces. We apply it to germanium, gold and magnesium oxide particles, and achieve a depth resolution of 1–2 Å, which is smaller than inter-atomic distances. PMID:26887849

  1. In-line three-dimensional holography of nanocrystalline objects at atomic resolution

    DOE PAGES

    Chen, F. -R.; Van Dyck, D.; Kisielowski, C.

    2016-02-18

    We report that resolution and sensitivity of the latest generation aberration-corrected transmission electron microscopes allow the vast majority of single atoms to be imaged with sub-Ångstrom resolution and their locations determined in an image plane with a precision that exceeds the 1.9-pm wavelength of 300 kV electrons. Such unprecedented performance allows expansion of electron microscopic investigations with atomic resolution into the third dimension. Here we show a general tomographic method to recover the three-dimensional shape of a crystalline particle from high-resolution images of a single projection without the need for sample rotation. The method is compatible with low dose ratemore » electron microscopy, which improves on signal quality, while minimizing electron beam-induced structure modifications even for small particles or surfaces. Lastly, we apply it to germanium, gold and magnesium oxide particles, and achieve a depth resolution of 1–2 Å, which is smaller than inter-atomic distances.« less

  2. Iowa Women of Achievement.

    ERIC Educational Resources Information Center

    Ohrn, Deborah Gore, Ed.

    1993-01-01

    This issue of the Goldfinch highlights some of Iowa's 20th century women of achievement. These women have devoted their lives to working for human rights, education, equality, and individual rights. They come from the worlds of politics, art, music, education, sports, business, entertainment, and social work. They represent Native Americans,…

  3. Achieving Peace through Education.

    ERIC Educational Resources Information Center

    Clarken, Rodney H.

    While it is generally agreed that peace is desirable, there are barriers to achieving a peaceful world. These barriers are classified into three major areas: (1) an erroneous view of human nature; (2) injustice; and (3) fear of world unity. In a discussion of these barriers, it is noted that although the consciousness and conscience of the world…

  4. Increasing Male Academic Achievement

    ERIC Educational Resources Information Center

    Jackson, Barbara Talbert

    2008-01-01

    The No Child Left Behind legislation has brought greater attention to the academic performance of American youth. Its emphasis on student achievement requires a closer analysis of assessment data by school districts. To address the findings, educators must seek strategies to remedy failing results. In a mid-Atlantic district of the Unites States,…

  5. Leadership Issues: Raising Achievement.

    ERIC Educational Resources Information Center

    Horsfall, Chris, Ed.

    This document contains five papers examining the meaning and operation of leadership as a variable affecting student achievement in further education colleges in the United Kingdom. "Introduction" (Chris Horsfall) discusses school effectiveness studies' findings regarding the relationship between leadership and effective schools, distinguishes…

  6. Achievements or Disasters?

    ERIC Educational Resources Information Center

    Goodwin, MacArthur

    2000-01-01

    Focuses on policy issues that have affected arts education in the twentieth century, such as: interest in discipline-based arts education, influence of national arts associations, and national standards and coordinated assessment. States that whether the policy decisions are viewed as achievements or disasters are for future determination. (CMK)

  7. Achieving True Consensus.

    ERIC Educational Resources Information Center

    Napier, Rod; Sanaghan, Patrick

    2002-01-01

    Uses the example of Vermont's Middlebury College to explore the challenges and possibilities of achieving consensus about institutional change. Discusses why, unlike in this example, consensus usually fails, and presents four demands of an effective consensus process. Includes a list of "test" questions on successful collaboration. (EV)

  8. School Students' Science Achievement

    ERIC Educational Resources Information Center

    Shymansky, James; Wang, Tzu-Ling; Annetta, Leonard; Everett, Susan; Yore, Larry D.

    2013-01-01

    This paper is a report of the impact of an externally funded, multiyear systemic reform project on students' science achievement on a modified version of the Third International Mathematics and Science Study (TIMSS) test in 33 small, rural school districts in two Midwest states. The systemic reform effort utilized a cascading leadership strategy…

  9. Essays on Educational Achievement

    ERIC Educational Resources Information Center

    Ampaabeng, Samuel Kofi

    2013-01-01

    This dissertation examines the determinants of student outcomes--achievement, attainment, occupational choices and earnings--in three different contexts. The first two chapters focus on Ghana while the final chapter focuses on the US state of Massachusetts. In the first chapter, I exploit the incidence of famine and malnutrition that resulted to…

  10. Assessing Handwriting Achievement.

    ERIC Educational Resources Information Center

    Ediger, Marlow

    Teachers in the school setting need to emphasize quality handwriting across the curriculum. Quality handwriting means that the written content is easy to read in either manuscript or cursive form. Handwriting achievement can be assessed, but not compared to the precision of assessing basic addition, subtraction, multiplication, and division facts.…

  11. Intelligence and Educational Achievement

    ERIC Educational Resources Information Center

    Deary, Ian J.; Strand, Steve; Smith, Pauline; Fernandes, Cres

    2007-01-01

    This 5-year prospective longitudinal study of 70,000+ English children examined the association between psychometric intelligence at age 11 years and educational achievement in national examinations in 25 academic subjects at age 16. The correlation between a latent intelligence trait (Spearman's "g"from CAT2E) and a latent trait of educational…

  12. Explorations in achievement motivation

    NASA Technical Reports Server (NTRS)

    Helmreich, Robert L.

    1982-01-01

    Recent research on the nature of achievement motivation is reviewed. A three-factor model of intrinsic motives is presented and related to various criteria of performance, job satisfaction and leisure activities. The relationships between intrinsic and extrinsic motives are discussed. Needed areas for future research are described.

  13. NCLB: Achievement Robin Hood?

    ERIC Educational Resources Information Center

    Bracey, Gerald W.

    2008-01-01

    In his "Wall Street Journal" op-ed on the 25th of anniversary of "A Nation At Risk", former assistant secretary of education Chester E. Finn Jr. applauded the report for turning U.S. education away from equality and toward achievement. It was not surprising, then, that in mid-2008, Finn arranged a conference to examine the potential "Robin Hood…

  14. Achieving All Our Ambitions

    ERIC Educational Resources Information Center

    Hartley, Tricia

    2009-01-01

    National learning and skills policy aims both to build economic prosperity and to achieve social justice. Participation in higher education (HE) has the potential to contribute substantially to both aims. That is why the Campaign for Learning has supported the ambition to increase the proportion of the working-age population with a Level 4…

  15. INTELLIGENCE, PERSONALITY AND ACHIEVEMENT.

    ERIC Educational Resources Information Center

    MUIR, R.C.; AND OTHERS

    A LONGITUDINAL DEVELOPMENTAL STUDY OF A GROUP OF MIDDLE CLASS CHILDREN IS DESCRIBED, WITH EMPHASIS ON A SEGMENT OF THE RESEARCH INVESTIGATING THE RELATIONSHIP OF ACHIEVEMENT, INTELLIGENCE, AND EMOTIONAL DISTURBANCE. THE SUBJECTS WERE 105 CHILDREN AGED FIVE TO 6.3 ATTENDING TWO SCHOOLS IN MONTREAL. EACH CHILD WAS ASSESSED IN THE AREAS OF…

  16. SALT and Spelling Achievement.

    ERIC Educational Resources Information Center

    Nelson, Joan

    A study investigated the effects of suggestopedic accelerative learning and teaching (SALT) on the spelling achievement, attitudes toward school, and memory skills of fourth-grade students. Subjects were 20 male and 28 female students from two self-contained classrooms at Kennedy Elementary School in Rexburg, Idaho. The control classroom and the…

  17. Appraising Reading Achievement.

    ERIC Educational Resources Information Center

    Ediger, Marlow

    To determine quality sequence in pupil progress, evaluation approaches need to be used which guide the teacher to assist learners to attain optimally. Teachers must use a variety of procedures to appraise student achievement in reading, because no one approach is adequate. Appraisal approaches might include: (1) observation and subsequent…

  18. Instantaneous three-dimensional sensing using spatial light modulator illumination with extended depth of field imaging

    PubMed Central

    Quirin, Sean; Peterka, Darcy S.; Yuste, Rafael

    2013-01-01

    Imaging three-dimensional structures represents a major challenge for conventional microscopies. Here we describe a Spatial Light Modulator (SLM) microscope that can simultaneously address and image multiple targets in three dimensions. A wavefront coding element and computational image processing enables extended depth-of-field imaging. High-resolution, multi-site three-dimensional targeting and sensing is demonstrated in both transparent and scattering media over a depth range of 300-1,000 microns. PMID:23842387

  19. A comparison of observed and analytically derived remote sensing penetration depths for turbid water

    NASA Technical Reports Server (NTRS)

    Morris, W. D.; Usry, J. W.; Witte, W. G.; Whitlock, C. H.; Guraus, E. A.

    1981-01-01

    The depth to which sunlight will penetrate in turbid waters was investigated. The tests were conducted in water with a single scattering albedo range, and over a range of solar elevation angles. Two different techniques were used to determine the depth of light penetration. It showed little change in the depth of sunlight penetration with changing solar elevation angle. A comparison of the penetration depths indicates that the best agreement between the two methods was achieved when the quasisingle scattering relationship was not corrected for solar angle. It is concluded that sunlight penetration is dependent on inherent water properties only.

  20. Are face representations depth cue invariant?

    PubMed

    Dehmoobadsharifabadi, Armita; Farivar, Reza

    2016-06-01

    The visual system can process three-dimensional depth cues defining surfaces of objects, but it is unclear whether such information contributes to complex object recognition, including face recognition. The processing of different depth cues involves both dorsal and ventral visual pathways. We investigated whether facial surfaces defined by individual depth cues resulted in meaningful face representations-representations that maintain the relationship between the population of faces as defined in a multidimensional face space. We measured face identity aftereffects for facial surfaces defined by individual depth cues (Experiments 1 and 2) and tested whether the aftereffect transfers across depth cues (Experiments 3 and 4). Facial surfaces and their morphs to the average face were defined purely by one of shading, texture, motion, or binocular disparity. We obtained identification thresholds for matched (matched identity between adapting and test stimuli), non-matched (non-matched identity between adapting and test stimuli), and no-adaptation (showing only the test stimuli) conditions for each cue and across different depth cues. We found robust face identity aftereffect in both experiments. Our results suggest that depth cues do contribute to forming meaningful face representations that are depth cue invariant. Depth cue invariance would require integration of information across different areas and different pathways for object recognition, and this in turn has important implications for cortical models of visual object recognition. PMID:27271993

  1. Pictorial depth probed through relative sizes

    PubMed Central

    Wagemans, Johan; van Doorn, Andrea J; Koenderink, Jan J

    2011-01-01

    In the physical environment familiar size is an effective depth cue because the distance from the eye to an object equals the ratio of its physical size to its angular extent in the visual field. Such simple geometrical relations do not apply to pictorial space, since the eye itself is not in pictorial space, and consequently the notion “distance from the eye” is meaningless. Nevertheless, relative size in the picture plane is often used by visual artists to suggest depth differences. The depth domain has no natural origin, nor a natural unit; thus only ratios of depth differences could have an invariant significance. We investigate whether the pictorial relative size cue yields coherent depth structures in pictorial spaces. Specifically, we measure the depth differences for all pairs of points in a 20-point configuration in pictorial space, and we account for these observations through 19 independent parameters (the depths of the points modulo an arbitrary offset), with no meaningful residuals. We discuss a simple formal framework that allows one to handle individual differences. We also compare the depth scale obtained by way of this method with depth scales obtained in totally different ways, finding generally good agreement. PMID:23145258

  2. Clutter depth discrimination using the wavenumber spectrum.

    PubMed

    Benjamin Reeder, D

    2014-01-01

    Clutter depth is a key parameter in mid-frequency active sonar systems to discriminate between sources of clutter and targets of interest. A method is needed to remotely discriminate clutter depth by information contained in the backscattered signal-without a priori knowledge of that depth. Presented here is an efficient approach for clutter depth estimation using the structure in the wavenumber spectrum. Based on numerical simulations for a simple test case in a shallow water waveguide, this technique demonstrates the potential capability to discriminate between a clutter source in the water column vs one on the seabed.

  3. Fundamental Limits of Spatial Resolution in PET

    PubMed Central

    Moses, William W.

    2010-01-01

    The fundamental limits of spatial resolution in positron emission tomography (PET) have been understood for many years. The physical size of the detector element usually plays the dominant role in determining resolution, but the combined contributions from acollinearity, positron range, penetration into the detector ring, and decoding errors in the detector modules often combine to be of similar size. In addition, the sampling geometry and statistical noise further degrade the effective resolution. This paper describes quantitatively describes these effects, discusses potential methods for reducing the magnitude of these effects, and computes the ultimately achievable spatial resolution for clinical and pre-clinical PET cameras. PMID:21804677

  4. KINOFORM LENSES - TOWARD NANOMETER RESOLUTION.

    SciTech Connect

    STEIN, A.; EVANS-LUTTERODT, K.; TAYLOR, A.

    2004-10-23

    While hard x-rays have wavelengths in the nanometer and sub-nanometer range, the ability to focus them is limited by the quality of sources and optics, and not by the wavelength. A few options, including reflective (mirrors), diffractive (zone plates) and refractive (CRL's) are available, each with their own limitations. Here we present our work with kinoform lenses which are refractive lenses with all material causing redundant 2{pi} phase shifts removed to reduce the absorption problems inherently limiting the resolution of refractive lenses. By stacking kinoform lenses together, the effective numerical aperture, and thus the focusing resolution, can be increased. The present status of kinoform lens fabrication and testing at Brookhaven is presented as well as future plans toward achieving nanometer resolution.

  5. High resolution optical DNA mapping

    NASA Astrophysics Data System (ADS)

    Baday, Murat

    Many types of diseases including cancer and autism are associated with copy-number variations in the genome. Most of these variations could not be identified with existing sequencing and optical DNA mapping methods. We have developed Multi-color Super-resolution technique, with potential for high throughput and low cost, which can allow us to recognize more of these variations. Our technique has made 10--fold improvement in the resolution of optical DNA mapping. Using a 180 kb BAC clone as a model system, we resolved dense patterns from 108 fluorescent labels of two different colors representing two different sequence-motifs. Overall, a detailed DNA map with 100 bp resolution was achieved, which has the potential to reveal detailed information about genetic variance and to facilitate medical diagnosis of genetic disease.

  6. An Exploration of the Needling Depth in Acupuncture: The Safe Needling Depth and the Needling Depth of Clinical Efficacy

    PubMed Central

    Lin, Jaung-Geng; Chou, Pei-Chi; Chu, Heng-Yi

    2013-01-01

    Objective. To explore the existing scientific information regarding safe needling depth of acupuncture points and the needling depth of clinical efficacy. Methods. We searched the PubMed, EMBASE, Cochrane, Allied and Complementary Medicine (AMED), The National Center for Complementary and Alternative Medicine (NCCAM), and China National Knowledge Infrastructure (CNKI) databases to identify relevant monographs and related references from 1991 to 2013. Chinese journals and theses/dissertations were hand searched. Results. 47 studies were recruited and divided into 6 groups by measuring tools, that is, MRI, in vivo evaluation, CT, ultrasound, dissected specimen of cadavers, and another group with clinical efficacy. Each research was analyzed for study design, definition of safe depth, and factors that would affect the measured depths. Depths of clinical efficacy were discussed from the perspective of de-qi and other clinical observations. Conclusions. Great inconsistency in depth of each point measured from different subject groups and tools exists. The definition of safe depth should be established through standardization. There is also lack of researches to compare the clinical efficacy. A well-designed clinical trial selecting proper measuring tools to decide the actual and advisable needling depth for each point, to avoid adverse effects or complications and promote optimal clinical efficacy, is a top priority. PMID:23935678

  7. Hydrogen analysis depth calibration by CORTEO Monte-Carlo simulation

    NASA Astrophysics Data System (ADS)

    Moser, M.; Reichart, P.; Bergmaier, A.; Greubel, C.; Schiettekatte, F.; Dollinger, G.

    2016-03-01

    Hydrogen imaging with sub-μm lateral resolution and sub-ppm sensitivity has become possible with coincident proton-proton (pp) scattering analysis (Reichart et al., 2004). Depth information is evaluated from the energy sum signal with respect to energy loss of both protons on their path through the sample. In first order, there is no angular dependence due to elastic scattering. In second order, a path length effect due to different energy loss on the paths of the protons causes an angular dependence of the energy sum. Therefore, the energy sum signal has to be de-convoluted depending on the matrix composition, i.e. mainly the atomic number Z, in order to get a depth calibrated hydrogen profile. Although the path effect can be calculated analytically in first order, multiple scattering effects lead to significant deviations in the depth profile. Hence, in our new approach, we use the CORTEO Monte-Carlo code (Schiettekatte, 2008) in order to calculate the depth of a coincidence event depending on the scattering angle. The code takes individual detector geometry into account. In this paper we show, that the code correctly reproduces measured pp-scattering energy spectra with roughness effects considered. With more than 100 μm thick Mylar-sandwich targets (Si, Fe, Ge) we demonstrate the deconvolution of the energy spectra on our current multistrip detector at the microprobe SNAKE at the Munich tandem accelerator lab. As a result, hydrogen profiles can be evaluated with an accuracy in depth of about 1% of the sample thickness.

  8. Alchemical hermeneutics of the Vesica Piscis: Symbol of depth psychology

    NASA Astrophysics Data System (ADS)

    O'Dell, Linda Kay

    The purpose of this study was to develop an understanding of the Vesica Piscis as the symbolic frame for depth psychology and the therapeutic relationship. The method of inquiry was hermeneutics and alchemical hermeneutics, informed theoretically by depth psychology. A theoretical description of the nature of the Vesica Piscis as a dynamic template and symbol for depth psychology and the therapeutic relationship resulted. Gathering the components of the therapeutic relationship into the shape of the Vesica Piscis, gave opportunity to explore what might be happening while treatment is taking place: somatically, psychologically, and emotionally. An investigation into the study of Soul placed the work of psychology within the central, innermost sacred space between—known symbolically as the Vesica Piscis. Imbued with a connectedness and relational welcoming, this symbol images the Greek goddess Hekate (Soul), as mediatrix between mind and matter. Psyche (soul), namesake of "psychology," continues her journey of finding meaning making, restitution, and solace in the therapeutic space as imaged by the Vesica Piscis. Her journey, moving through the generations, becomes the journey of the therapeutic process—one that finds resolution in relationship. Psyche is sought out in the macrocosmic archetypal realm of pure energy, the prima material that forms and coalesces both in response and likewise, creates a response through symbols, images, and imagination. The field was explored from the depth psychological perspective as: the unconscious, consciousness, and archetypal, and in physics as: the quantum field, morphic resonance, and the holographic field. Gaining an understanding of the underlying qualities of the field placed the symbol in its embedded context, allowing for further definition as to how the symbol potentially was either an extension of the field, or served as a constellating factor. Depth psychology, as a scientific discipline, is in need of a symbol that

  9. Mapping the structure and depth to magnetic basement in the United States using the magnetic tilt-depth method

    NASA Astrophysics Data System (ADS)

    Salem, A.; Williams, S.; Fairhead, J.; Ravat, D.; Blakely, R.

    2008-05-01

    We provide a rationale for rapidly assessing the depth and structure of sedimentary basins from magnetic anomaly data. Our methodology is based on "tilt-depth" calculated strictly from first-order derivatives of the total magnetic field. We assume a simple buried vertical contact model such that the 0 degree contour of the tilt derivative closely follows the edge of the vertical contact, while the distance between the 0 and +/-45 degree contours provides an estimate of the depth to the top of the buried contact. We have applied the tilt-depth method to two magnetic databases with very different scales. In the first application, we used the Magnetic Anomaly Map of North America covering the continental United States, gridded at a sample interval of 1 km. Calculated depths show a strong correlation with known areas of shallow basement and sedimentary basins. To quantitatively evaluate the results, we low-pass filtered the calculated depths, desampled the grid to a 1-degree sample interval, and compared with a grid of sediment thickness based on drilling data (Laske and Masters, 1997). In visual comparisons, these two datasets show a striking correlation between basement highs and lows, and, quantitatively, the overall correlation coefficient between the two grids is 0.87. We also applied the tilt-depth methodology to high-resolution aeromagnetic data from the Olympic Peninsula of Washington State. To first order, the Olympic Peninsula is a massive east-plunging anticline consisting of two distinct subduction-related terranes: An essentially nonmagnetic core of highly deformed Tertiary sedimentary rocks, and a periphery of highly magnetic, early Eocene volcanic rocks. The tilt-depth method successfully identified a number of important tectonic elements known from geologic mapping. The steeply dipping thrust contact between core and periphery rocks was clearly delineated, and other more subtle magnetic anomalies within the periphery volcanic rocks and even within the

  10. The Astrophysical Plasmadynamic Explorer (APEX): A High Resolution Spectroscopic Observatory

    NASA Astrophysics Data System (ADS)

    Kowalski, M. P.; Cruddace, R. G.; Wood, K. S.; Yentis, D. J.; Gursky, H.; Barbee, T. W., Jr.; Goldstein, W. H.; Kordas, J. F.; Fritz, G. G.; Barstow, M. A.; Bannister, N. P.; Lapington, J. S.

    2002-05-01

    EUVE and the ROSAT WFC have left a tremendous legacy in astrophysics at EUV wavelengths. More recently, Chandra and XMM-Newton have demonstrated at X-ray wavelengths the power of high-resolution astronomical spectroscopy, which allows the identification of weak emission lines, the measurement of Doppler shifts and line profiles, and the detection of narrow absorption features. This leads to a complete understanding of the density, temperature, abundance, magnetic, and dynamic structure of astrophysical plasmas. However, the termination of the EUVE mission has left a gaping hole in spectral coverage at crucial EUV wavelengths ( 100-300 Angstroms), where hot (105-108 K) plasmas radiate most strongly and produce critical spectral diagnostics. CHIPS will fill this hole only partially as it is optimized for diffuse emission and has only moderate resolution (R 150). For discrete sources, we have successfully flown a follow-on instrument to the EUVE spectrometer (Aeff 1 cm2, R 400), the high-resolution spectrometer J-PEX (Aeff 3 cm2, R 3000). In this paper we build on the J-PEX prototype and present a strawman design for an orbiting spectroscopic observatory, APEX, a SMEX-class instrument containing a suite of spectrometers that together achieve both high effective area (>20 cm2) and high spectral resolution ( 10000) over the range 100-300 Angstroms. We discuss in depth the optical design, the wavelength coverage, and the effective area. This work is supported by the Office of Naval Research and NRL, and by NASA Space Astrophysics and Research Analysis grants

  11. High spatial resolution restoration of IRAS images

    NASA Technical Reports Server (NTRS)

    Grasdalen, Gary L.; Inguva, R.; Dyck, H. Melvin; Canterna, R.; Hackwell, John A.

    1990-01-01

    A general technique to improve the spatial resolution of the IRAS AO data was developed at The Aerospace Corporation using the Maximum Entropy algorithm of Skilling and Gull. The technique has been applied to a variety of fields and several individual AO MACROS. With this general technique, resolutions of 15 arcsec were achieved in 12 and 25 micron images and 30 arcsec in 60 and 100 micron images. Results on galactic plane fields show that both photometric and positional accuracy achieved in the general IRAS survey are also achieved in the reconstructed images.

  12. Evaluation of factors affecting resolution of shallow water bottom features

    NASA Technical Reports Server (NTRS)

    Mason, C. C.; Norris, D. R.; Browne, I. D.

    1972-01-01

    To ensure good aerial photography, the effects that factors such as submergence depth, sun angle, film and filter type, exposure, aircraft altitude, and polarization have on the photographic resolution of an underwater object must be determined. Various subjects were photographed, such as the deck of a small submersible, colored and gray scale panels, and natural bottom features. No underwater resolution target was used.

  13. Developing terahertz imaging equation and enhancement of the resolution of terahertz images using deconvolution

    NASA Astrophysics Data System (ADS)

    Ahi, Kiarash; Anwar, Mehdi

    2016-04-01

    This paper introduces a novel reconstruction approach for enhancing the resolution of the terahertz (THz) images. For this purpose the THz imaging equation is derived. According to our best knowledge we are reporting the first THz imaging equation by this paper. This imaging equation is universal for THz far-field imaging systems and can be used for analyzing, describing and modeling of these systems. The geometry and behavior of Gaussian beams in far-field region imply that the FWHM of the THz beams diverge as the frequencies of the beams decrease. Thus, the resolution of the measurement decreases in lower frequencies. On the other hand, the depth of penetration of THz beams decreases as frequency increases. Roughly speaking beams in sub 1.5 THz, are transmitted into integrated circuit (IC) packages and the similar packaged objects. Thus, it is not possible to use the THz pulse with higher frequencies in order to achieve higher resolution inspection of packaged items. In this paper, after developing the 3-D THz point spread function (PSF) of the scanning THz beam and then the THz imaging equation, THz images are enhanced through deconvolution of the THz PSF and THz images. As a result, the resolution has been improved several times beyond the physical limitations of the THz measurement setup in the far-field region and sub-Nyquist images have been achieved. Particularly, MSE and SSIḾ have been increased by 27% and 50% respectively. Details as small as 0.2 mm were made visible in the THz images which originally reveals no details smaller than 2.2 mm. In other words the resolution of the images has been increased by 10 times. The accuracy of the reconstructed images was proved by high resolution X-ray images.

  14. Project ACHIEVE final report

    SciTech Connect

    1997-06-13

    Project ACHIEVE was a math/science academic enhancement program aimed at first year high school Hispanic American students. Four high schools -- two in El Paso, Texas and two in Bakersfield, California -- participated in this Department of Energy-funded program during the spring and summer of 1996. Over 50 students, many of whom felt they were facing a nightmare future, were given the opportunity to work closely with personal computers and software, sophisticated calculators, and computer-based laboratories -- an experience which their regular academic curriculum did not provide. Math and science projects, exercises, and experiments were completed that emphasized independent and creative applications of scientific and mathematical theories to real world problems. The most important outcome was the exposure Project ACHIEVE provided to students concerning the college and technical-field career possibilities available to them.

  15. Monocular depth perception using image processing and machine learning

    NASA Astrophysics Data System (ADS)

    Hombali, Apoorv; Gorde, Vaibhav; Deshpande, Abhishek

    2011-10-01

    This paper primarily exploits some of the more obscure, but inherent properties of camera and image to propose a simpler and more efficient way of perceiving depth. The proposed method involves the use of a single stationary camera at an unknown perspective and an unknown height to determine depth of an object on unknown terrain. In achieving so a direct correlation between a pixel in an image and the corresponding location in real space has to be formulated. First, a calibration step is undertaken whereby the equation of the plane visible in the field of view is calculated along with the relative distance between camera and plane by using a set of derived spatial geometrical relations coupled with a few intrinsic properties of the system. The depth of an unknown object is then perceived by first extracting the object under observation using a series of image processing steps followed by exploiting the aforementioned mapping of pixel and real space coordinate. The performance of the algorithm is greatly enhanced by the introduction of reinforced learning making the system independent of hardware and environment. Furthermore the depth calculation function is modified with a supervised learning algorithm giving consistent improvement in results. Thus, the system uses the experience in past and optimizes the current run successively. Using the above procedure a series of experiments and trials are carried out to prove the concept and its efficacy.

  16. A comparison of hydrographically and optically derived mixed layer depths

    USGS Publications Warehouse

    Zawada, D.G.; Zaneveld, J.R.V.; Boss, E.; Gardner, W.D.; Richardson, M.J.; Mishonov, A.V.

    2005-01-01

    Efforts to understand and model the dynamics of the upper ocean would be significantly advanced given the ability to rapidly determine mixed layer depths (MLDs) over large regions. Remote sensing technologies are an ideal choice for achieving this goal. This study addresses the feasibility of estimating MLDs from optical properties. These properties are strongly influenced by suspended particle concentrations, which generally reach a maximum at pycnoclines. The premise therefore is to use a gradient in beam attenuation at 660 nm (c660) as a proxy for the depth of a particle-scattering layer. Using a global data set collected during World Ocean Circulation Experiment cruises from 1988-1997, six algorithms were employed to compute MLDs from either density or temperature profiles. Given the absence of published optically based MLD algorithms, two new methods were developed that use c660 profiles to estimate the MLD. Intercomparison of the six hydrographically based algorithms revealed some significant disparities among the resulting MLD values. Comparisons between the hydrographical and optical approaches indicated a first-order agreement between the MLDs based on the depths of gradient maxima for density and c660. When comparing various hydrographically based algorithms, other investigators reported that inherent fluctuations of the mixed layer depth limit the accuracy of its determination to 20 m. Using this benchmark, we found a ???70% agreement between the best hydrographical-optical algorithm pairings. Copyright 2005 by the American Geophysical Union.

  17. Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation

    PubMed Central

    Uttam, Shikhar; Bista, Rajan K.; Staton, Kevin; Alexandrov, Sergey; Choi, Serah; Bakkenist, Christopher J.; Hartman, Douglas J.; Brand, Randall E.; Liu, Yang

    2013-01-01

    We present depth-resolved spatial-domain low-coherence quantitative phase microscopy, a simple approach that utilizes coherence gating to construct a depth-resolved structural feature vector quantifying sub-resolution axial structural changes at different optical depths within the sample. We show that this feature vector is independent of sample thickness variation, and identifies nanoscale structural changes in clinically prepared samples. We present numerical simulations and experimental validation to demonstrate the feasibility of the approach. We also perform experiments using unstained cells to investigate the nanoscale structural changes in regulated cell proliferation through cell cycle and chromatin decondensation induced by histone acetylation. PMID:23577294

  18. Best Technology Practices of Conflict Resolution Specialists: A Case Study of Online Dispute Resolution at United States Universities

    ERIC Educational Resources Information Center

    Law, Kimberli Marie

    2013-01-01

    The purpose of this study was to remedy the paucity of knowledge about higher education's conflict resolution practice of online dispute resolution by providing an in-depth description of mediator and instructor online practices. Telephone interviews were used as the primary data collection method. Eleven interview questions were relied upon to…

  19. Effect of acupuncture depth on muscle pain

    PubMed Central

    2011-01-01

    Background While evidence supports efficacy of acupuncture and/or dry needling in treating musculoskeletal pain, it is unclear which needling method is most effective. This study aims to determine the effects of depth of needle penetration on muscle pain. Methods A total of 22 healthy volunteers performed repeated eccentric contractions to induce muscle soreness in their extensor digital muscle. Subjects were assigned randomly to four groups, namely control group, skin group (depth of 3 mm: the extensor digital muscle), muscle group (depth of 10 mm: the extensor digital muscle) and non-segmental group (depth of 10 mm: the anterior tibial muscle). Pressure pain threshold and electrical pain threshold of the skin, fascia and muscle were measured at a point 20 mm distal to the maximum tender point on the second day after the exercise. Results Pressure pain thresholds of skin group (depth of 3 mm: the extensor digital muscle) and muscle group (depth of 10 mm: the extensor digital muscle) were significantly higher than the control group, whereas the electrical pain threshold at fascia of muscle group (depth of 10 mm: the extensor digital muscle) was a significantly higher than control group; however, there was no significant difference between the control and other groups. Conclusion The present study shows that acupuncture stimulation of muscle increases the PPT and EPT of fascia. The depth of needle penetration is important for the relief of muscle pain. PMID:21696603

  20. "Depth" Matters in High School Science Studies

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2009-01-01

    This article reports on the findings of a recent study that examines one of the most enduring debates in science instruction--whether "depth" or "breadth" of knowledge is most important. Its authors come down on the side of depth. The study found that high school students who focus more intensely on core topics within their biology, chemistry, and…

  1. Improved Boundary Layer Depth Retrievals from MPLNET

    NASA Technical Reports Server (NTRS)

    Lewis, Jasper R.; Welton, Ellsworth J.; Molod, Andrea M.; Joseph, Everette

    2013-01-01

    Continuous lidar observations of the planetary boundary layer (PBL) depth have been made at the Micropulse Lidar Network (MPLNET) site in Greenbelt, MD since April 2001. However, because of issues with the operational PBL depth algorithm, the data is not reliable for determining seasonal and diurnal trends. Therefore, an improved PBL depth algorithm has been developed which uses a combination of the wavelet technique and image processing. The new algorithm is less susceptible to contamination by clouds and residual layers, and in general, produces lower PBL depths. A 2010 comparison shows the operational algorithm overestimates the daily mean PBL depth when compared to the improved algorithm (1.85 and 1.07 km, respectively). The improved MPLNET PBL depths are validated using radiosonde comparisons which suggests the algorithm performs well to determine the depth of a fully developed PBL. A comparison with the Goddard Earth Observing System-version 5 (GEOS-5) model suggests that the model may underestimate the maximum daytime PBL depth by 410 m during the spring and summer. The best agreement between MPLNET and GEOS-5 occurred during the fall and they diered the most in the winter.

  2. Contextualizing Range and Depth in Indian English.

    ERIC Educational Resources Information Center

    D'Souza, Jean

    2001-01-01

    Examines the range and depth of English in India and argues that these Kachruvian notions go a long way towards explaining how the language is used, exploited, extended, and recreated in the sub-continent. Data, both written and spoken, are presented, and it is suggested that in-depth analyses of such data are a prerequisite to any real…

  3. Differential Cognitive Cues in Pictorial Depth Perception.

    ERIC Educational Resources Information Center

    Omari, Issa M.; Cook, Harold

    The experiment described in this report investigates the effects of various cognitive cues in questions asked regarding the relationship of elements in pictorial depth perception. The subjects of this study are 40 third grade Black and Puerto Rican children. They are confronted with four pictures from the Hudson Depth Perception Tests and asked to…

  4. Depth of origin of magma in eruptions

    PubMed Central

    Becerril, Laura; Galindo, Ines; Gudmundsson, Agust; Morales, Jose Maria

    2013-01-01

    Many volcanic hazard factors - such as the likelihood and duration of an eruption, the eruption style, and the probability of its triggering large landslides or caldera collapses - relate to the depth of the magma source. Yet, the magma source depths are commonly poorly known, even in frequently erupting volcanoes such as Hekla in Iceland and Etna in Italy. Here we show how the length-thickness ratios of feeder dykes can be used to estimate the depth to the source magma chamber. Using this method, accurately measured volcanic fissures/feeder-dykes in El Hierro (Canary Islands) indicate a source depth of 11–15 km, which coincides with the main cloud of earthquake foci surrounding the magma chamber associated with the 2011–2012 eruption of El Hierro. The method can be used on widely available GPS and InSAR data to calculate the depths to the source magma chambers of active volcanoes worldwide. PMID:24067336

  5. Contour detection combined with depth information

    NASA Astrophysics Data System (ADS)

    Xiao, Jie; Cai, Chao

    2015-12-01

    Many challenging computer vision problems have been proven to benefit from the incorporation of depth information, to name a few, semantic labellings, pose estimations and even contour detection. Different objects have different depths from a single monocular image. The depth information of one object is coherent and the depth information of different objects may vary discontinuously. Meanwhile, there exists a broad non-classical receptive field (NCRF) outside the classical receptive field (CRF). The response of the central neuron is affected not only by the stimulus inside the CRF, but also modulated by the stimulus surrounding it. The contextual modulation is mediated by horizontal connections across the visual cortex. Based on the findings and researches, a biological-inspired contour detection model which combined with depth information is proposed in this paper.

  6. Depth of origin of magma in eruptions.

    PubMed

    Becerril, Laura; Galindo, Ines; Gudmundsson, Agust; Morales, Jose Maria

    2013-01-01

    Many volcanic hazard factors--such as the likelihood and duration of an eruption, the eruption style, and the probability of its triggering large landslides or caldera collapses--relate to the depth of the magma source. Yet, the magma source depths are commonly poorly known, even in frequently erupting volcanoes such as Hekla in Iceland and Etna in Italy. Here we show how the length-thickness ratios of feeder dykes can be used to estimate the depth to the source magma chamber. Using this method, accurately measured volcanic fissures/feeder-dykes in El Hierro (Canary Islands) indicate a source depth of 11-15 km, which coincides with the main cloud of earthquake foci surrounding the magma chamber associated with the 2011-2012 eruption of El Hierro. The method can be used on widely available GPS and InSAR data to calculate the depths to the source magma chambers of active volcanoes worldwide. PMID:24067336

  7. Depth perception through circular movements of dots.

    PubMed

    Ito, Hiroyuki

    2010-01-01

    Elements that move with velocity gradients have been shown to give the impression of depth. In this study, it was found that dots in circular motion around a line of sight give a depth impression corresponding to the gradients of the angular velocities of circular motion on a screen. The results of two experiments show that depth perception through circular motion is as effective as that through expansion or spiral motion, but less effective than that through lateral motion parallax when the local speed distributions on the screen are matched. The present depth effect shows that expansion-contraction, spiral, and circular motions are a continuum in terms of producing depth effects; they differ from lateral motion parallax.

  8. Depth of origin of magma in eruptions.

    PubMed

    Becerril, Laura; Galindo, Ines; Gudmundsson, Agust; Morales, Jose Maria

    2013-09-26

    Many volcanic hazard factors--such as the likelihood and duration of an eruption, the eruption style, and the probability of its triggering large landslides or caldera collapses--relate to the depth of the magma source. Yet, the magma source depths are commonly poorly known, even in frequently erupting volcanoes such as Hekla in Iceland and Etna in Italy. Here we show how the length-thickness ratios of feeder dykes can be used to estimate the depth to the source magma chamber. Using this method, accurately measured volcanic fissures/feeder-dykes in El Hierro (Canary Islands) indicate a source depth of 11-15 km, which coincides with the main cloud of earthquake foci surrounding the magma chamber associated with the 2011-2012 eruption of El Hierro. The method can be used on widely available GPS and InSAR data to calculate the depths to the source magma chambers of active volcanoes worldwide.

  9. Mapping Soil Depth with Topographic and Land Cover Attributes from Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Chen, Cheng-Ru; Chen, Chi-Farn; Son, Nguyen-Thanh; Lau, Va-Khin

    2016-04-01

    Soil depth is an important parameter for identification of the overused slope land in Taiwan. The retrieval of high resolution soil depth at a large scale is costly and time-consuming. The main objective of this study is to develop an approach to estimate soil depths using satellite data with the aid of field survey data in Taiwan. The data were processed using the soil-landscape regression kriging model. The predictor variables, including elevation, slope, aspect, curvature, topographic wetness, spectral indices, and land use, derived from remotely sensed data were used as model inputs for the soil depth estimation. In this study, topographic attributes were derived from an 5-m resolution digital elevation model, and the land-use map and spectral indices were obtained through interpretation of Landsat-8 data. The absolute mean and root mean-square errors were used to access the reliability of the prediction, indicating a goodness-of-fit of the estimation model. The results of soil depth estimation compared with the field survey data indicated close relationship between these two datasets. The results obtained from this study could spatially provide quantitative information of soil depths, which is an important indicator for assessing the overused slope land. The methods were thus proposed for retrieval of soil depths in Taiwan.

  10. Modification of closure depths by synchronisation of severe seas and high water levels

    NASA Astrophysics Data System (ADS)

    Soomere, Tarmo; Männikus, Rain; Pindsoo, Katri; Kudryavtseva, Nadezhda; Eelsalu, Maris

    2016-10-01

    The closure depth indicates the depth down to which storm waves maintain a universal shape of the coastal profile. It is thus a key parameter of the coastal zones for a variety of engineering and ecosystem applications. Its values are commonly estimated with respect to the long-term mean water level. The present study re-evaluates closure depths for microtidal water bodies where the wave loads are highly correlated with the course of the water level. The test area is the eastern Baltic Sea. The closure depth is calculated for the eastern Baltic Sea coast with a resolution of 5.5 km and the vicinity of Tallinn Bay with a resolution of 0.5 km. While the classic values of closure depth are extracted from statistics of the roughest seas, the present analysis is based on single values of a proxy of the instantaneous closure depth. These values are evaluated from numerically simulated time series of wave properties and water levels. The water level-adjusted closure depths are almost equal to the classic values at the coasts of Lithuania but are up to 10% smaller at the Baltic Proper coasts of Latvia and Estonia. The difference is up to 20% in bayheads of the Gulf of Finland.

  11. [High-resolution magnetoencephalography--studies with a small-volume phantom].

    PubMed

    Hagner, T; Eiselt, M; Giessler, F; Hansen, E; Haueisen, J; Nowak, H

    1999-03-01

    To investigate the spatiotemporal organisation of neuronal processes in an animal model using magnetoencephalography (MEG), a high temporal resolution (ms) and an appropriate spatial resolution of about 1 mm is necessary. With the aim of determining the localization error and the resolution power of high-resolution MEG systems, we developed a phantom capable of simulating the characteristics of animal models. The phantom enables us to variably position at least two magnetic field sources to within 0.1 mm. For source localization on the basis of the magnetic field data, a spatial filtering algorithm was used. The investigation of a 16-channel micro SQUID-MEG system with a current dipole orientated tangentially to the phantom surface produced the following localization data (min ... max, x, y--horizontal plane, z--depth); systematic localization error e(x) = 1.16 ... 1.67 mm, e(y) = -1.01 ... -1.28 mm, e(z) = -5.22 ... -7.64 mm, standard deviation of the individual measurements perpendicular to the dipole axis s(perp) = 0.05 ... 0.22 mm, along this axis s(long) = 0.20 ... 1.73 mm, in the depths sz = 0.17 ... 3.17 mm. The "goodness of fit" was > 95%. Separation of two dipoles was still possible for parallel dipoles at a distance apart of d(parallel) = 0.03 mm and for those oriented perpendicularly to each other at a distance apart of d(perp) = 0.10 mm. On the basis of these results we conclude that the MEG system can achieve a resolution sufficient to permit the investigation of neuronal microstructures. The spatial errors detected were related to sensor position in the cryostatic vessel as well as to external low-frequency noise.

  12. Dilation framing camera with 4 ps resolution

    NASA Astrophysics Data System (ADS)

    Cai, Houzhi; Zhao, Xin; Liu, Jinyuan; Xie, Weixin; Bai, Yanli; Lei, Yunfei; Liao, Yubo; Niu, Hanben

    2016-04-01

    A framing camera using pulse-dilation technology is reported in this article. The camera uses pulse dilation of an electron signal from a pulsed photo-cathode (PC) to achieve high temporal resolution. While the PC is not pulsed, the measured temporal resolution of the camera without pulse-dilation is about 71 ps. While the excitation pulse is applied on the PC, the measured temporal resolution is improved to 4 ps by using the pulse-dilation technology. The spatial resolution of the dilation framing camera is also measured, which is better than 100 μm. The relationship between the temporal resolution and the PC bias voltage is obtained. The variation of the temporal resolution with the gradient of the PC excitation pulse is also provided.

  13. Picowatt Resolution Calorimetry for Micro and Nanoscale Energy Transport Studies

    NASA Astrophysics Data System (ADS)

    Sadat, Seid H.

    Precise quantification of energy transport is key to obtaining insights into a wide range of phenomena across various disciplines including physics, chemistry, biology and engineering. This thesis describes technical advancements into heat-flow calorimetry which enable measurement of energy transport at micro and nanoscales with picowatt resolution. I have developed two types of microfabricated calorimeter devices and demonstrated single digit picowatt resolution at room temperature. Both devices incorporate two distinct features; an active area isolated by a thermal conductance (GTh) of less than 1 microW/K and a high resolution thermometer with temperature resolution (DeltaTres) in the micro kelvin regime. These features enable measurements of heat currents (q) with picowatt resolution (q= Th xDeltaTres). In the first device the active area is suspended via silicon nitride beams with excellent thermal isolation (~600 nW/K) and a bimaterial cantilever (BMC) thermometer with temperature resolution of ~6 microK. Taken together this design enabled calorimetric measurements with 4 pW resolution. In the second device, the BMC thermometry technique is replaced by a high-resolution resistance thermometry scheme. A detailed noise analysis of resistance thermometers, confirmed by experimental data, enabled me to correctly predict the resolution of different measurement schemes and propose techniques to achieve an order of magnitude improvement in the resolution of resistive thermometers. By incorporating resistance thermometers with temperature resolution of ~30 microK, combined with a thermal isolation of ~150 nW/K, I demonstrated an all-electrical calorimeter device with a resolution of ~ 5 pW. Finally, I used these calorimeters to study Near-Field Radiative Heat Transfer (NF-RHT). Using these devices, we studied--for the first time--the effect of film thickness on the NF-RHT between two dielectric surfaces. We showed that even a very thin film (~50 nm) of silicon

  14. Does achievement motivation mediate the semantic achievement priming effect?

    PubMed

    Engeser, Stefan; Baumann, Nicola

    2014-10-01

    The aim of our research was to understand the processes of the prime-to-behavior effects with semantic achievement primes. We extended existing models with a perspective from achievement motivation theory and additionally used achievement primes embedded in the running text of excerpts of school textbooks to simulate a more natural priming condition. Specifically, we proposed that achievement primes affect implicit achievement motivation and conducted pilot experiments and 3 main experiments to explore this proposition. We found no reliable positive effect of achievement primes on implicit achievement motivation. In light of these findings, we tested whether explicit (instead of implicit) achievement motivation is affected by achievement primes and found this to be the case. In the final experiment, we found support for the assumption that higher explicit achievement motivation implies that achievement priming affects the outcome expectations. The implications of the results are discussed, and we conclude that primes affect achievement behavior by heightening explicit achievement motivation and outcome expectancies. PMID:24820250

  15. Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth.

    PubMed

    Fromer, Menachem; Moran, Jennifer L; Chambert, Kimberly; Banks, Eric; Bergen, Sarah E; Ruderfer, Douglas M; Handsaker, Robert E; McCarroll, Steven A; O'Donovan, Michael C; Owen, Michael J; Kirov, George; Sullivan, Patrick F; Hultman, Christina M; Sklar, Pamela; Purcell, Shaun M

    2012-10-01

    Sequencing of gene-coding regions (the exome) is increasingly used for studying human disease, for which copy-number variants (CNVs) are a critical genetic component. However, detecting copy number from exome sequencing is challenging because of the noncontiguous nature of the captured exons. This is compounded by the complex relationship between read depth and copy number; this results from biases in targeted genomic hybridization, sequence factors such as GC content, and batching of samples during collection and sequencing. We present a statistical tool (exome hidden Markov model [XHMM]) that uses principal-component analysis (PCA) to normalize exome read depth and a hidden Markov model (HMM) to discover exon-resolution CNV and genotype variation across samples. We evaluate performance on 90 schizophrenia trios and 1,017 case-control samples. XHMM detects a median of two rare (<1%) CNVs per individual (one deletion and one duplication) and has 79% sensitivity to similarly rare CNVs overlapping three or more exons discovered with microarrays. With sensitivity similar to state-of-the-art methods, XHMM achieves higher specificity by assigning quality metrics to the CNV calls to filter out bad ones, as well as to statistically genotype the discovered CNV in all individuals, yielding a trio call set with Mendelian-inheritance properties highly consistent with expectation. We also show that XHMM breakpoint quality scores enable researchers to explicitly search for novel classes of structural variation. For example, we apply XHMM to extract those CNVs that are highly likely to disrupt (delete or duplicate) only a portion of a gene. PMID:23040492

  16. High resolution A/D conversion based on piecewise conversion at lower resolution

    DOEpatents

    Terwilliger, Steve

    2012-06-05

    Piecewise conversion of an analog input signal is performed utilizing a plurality of relatively lower bit resolution A/D conversions. The results of this piecewise conversion are interpreted to achieve a relatively higher bit resolution A/D conversion without sampling frequency penalty.

  17. Depth Analogy: Data-Driven Approach for Single Image Depth Estimation Using Gradient Samples.

    PubMed

    Choi, Sunghwan; Min, Dongbo; Ham, Bumsub; Kim, Youngjung; Oh, Changjae; Sohn, Kwanghoon

    2015-12-01

    Inferring scene depth from a single monocular image is a highly ill-posed problem in computer vision. This paper presents a new gradient-domain approach, called depth analogy, that makes use of analogy as a means for synthesizing a target depth field, when a collection of RGB-D image pairs is given as training data. Specifically, the proposed method employs a non-parametric learning process that creates an analogous depth field by sampling reliable depth gradients using visual correspondence established on training image pairs. Unlike existing data-driven approaches that directly select depth values from training data, our framework transfers depth gradients as reconstruction cues, which are then integrated by the Poisson reconstruction. The performance of most conventional approaches relies heavily on the training RGB-D data used in the process, and such a dependency severely degenerates the quality of reconstructed depth maps when the desired depth distribution of an input image is quite different from that of the training data, e.g., outdoor versus indoor scenes. Our key observation is that using depth gradients in the reconstruction is less sensitive to scene characteristics, providing better cues for depth recovery. Thus, our gradient-domain approach can support a great variety of training range datasets that involve substantial appearance and geometric variations. The experimental results demonstrate that our (depth) gradient-domain approach outperforms existing data-driven approaches directly working on depth domain, even when only uncorrelated training datasets are available. PMID:26529766

  18. Investigation of depth-area relationships associated with nanoindentations

    SciTech Connect

    Riester, L.; Ferber, M.K.

    1994-10-01

    Determination of hardness from indentation testing requires the measurement of the contact area. For indents generated at very low loads (<20 mN) or shallow depths (<250 nm), optical methods do not have sufficient resolution. One approach utilized in current state-of-the-art mechanical properties microprobes (MPM) involves the measurement of indenter depth. Calculation of the plastic area then requires a relation between depth and contact area. This relation is generally derived either by assuming the indenter is perfectly sharp (``Ideal Indenter`` assumption) or by calibrating the shape using materials having known hardness and elastic modulus values. The validity of both approaches was examined by using a Scanning Force Microprobe (SFM) to measure the actual dimensions of the residual impressions made by the MPM. The SFM data revealed that the ``Ideal Indenter`` assumption underestimates the actual plastic area. This result accounts for the fact that hardness values measured with the MPM are typically higher than those obtained with conventional hardness testers.

  19. Real-Time Depth Measurement In A Stereoscopic Television Display

    NASA Astrophysics Data System (ADS)

    Robinson, M.; Sood, S. C.

    1983-04-01

    A working prototype three-dimensional television display has been constructed and initial feasibility studies have been carried out. The system employs the time division technique which takes advantage of the interlace facility on the standard television display and incorporates electro-optic viewing spectacles for the observer. Improvements to the basic system have been carried out which include remotely triggered viewing spectacles, thus giving greater freedom of movement to the observer and also an increased switching rate to reduce the effects of flicker. It soon became apparent that a system containing an integral real time depth measurement facility would be attractive to potential users. The method used is the application of a photogrammetic technique to the display in order to provide a real time three dimensional viewing and depth measurement facility. Present available techniques involve processing a stereoscopic pair of photographs which introduces an obvious inherent time delay. For many applications a real time technique has advantages even though the depth resolution is unlikely to be as good as the standard photographic system.

  20. Efficient patch-based approach for compressive depth imaging.

    PubMed

    Yuan, Xin; Liao, Xuejun; Llull, Patrick; Brady, David; Carin, Lawrence

    2016-09-20

    We present efficient camera hardware and algorithms to capture images with extended depth of field. The camera moves its focal plane via a liquid lens and modulates the scene at different focal planes by shifting a fixed binary mask, with synchronization achieved by using the same triangular wave to control the focal plane and the pizeoelectronic translator that shifts the mask. Efficient algorithms are developed to reconstruct the all-in-focus image and the depth map from a single coded exposure, and various sparsity priors are investigated to enhance the reconstruction, including group sparsity, tree structure, and dictionary learning. The algorithms naturally admit a parallel computational structure due to the independent patch-level operations. Experimental results on both simulation and real datasets demonstrate the efficacy of the new hardware and the inversion algorithms. PMID:27661583

  1. Interactive projection for aerial dance using depth sensing camera

    NASA Astrophysics Data System (ADS)

    Dubnov, Tammuz; Seldess, Zachary; Dubnov, Shlomo

    2014-02-01

    This paper describes an interactive performance system for oor and Aerial Dance that controls visual and sonic aspects of the presentation via a depth sensing camera (MS Kinect). In order to detect, measure and track free movement in space, 3 degree of freedom (3-DOF) tracking in space (on the ground and in the air) is performed using IR markers. Gesture tracking and recognition is performed using a simpli ed HMM model that allows robust mapping of the actor's actions to graphics and sound. Additional visual e ects are achieved by segmentation of the actor body based on depth information, allowing projection of separate imagery on the performer and the backdrop. Artistic use of augmented reality performance relative to more traditional concepts of stage design and dramaturgy are discussed.

  2. Remotely Measuring Snow Depth in Inaccessible Terrain

    NASA Astrophysics Data System (ADS)

    Dixon, D.; Boon, S.

    2010-12-01

    In watershed-scale studies of snow accumulation, high alpine areas are typically important accumulation areas. While snow depth measurements may not be collected in these regions due to avalanche danger, failing to include them in basin-wide estimates of snow accumulation may lead to large underestimates of basin-scale water yield. We present a new method to measure spatially distributed point snow depths remotely. Previously described methods using terrestrial laser scanning (TLS) systems, airborne light detection and ranging (LiDAR) systems, and hand-held laser distance meters have several limitations related to cost, data processing, and accuracy, thus reducing their applicability. The use of a modern robotic total station attempts to resolve these limitations. Total stations have much greater measurement accuracy than laser distance meters, and are significantly less expensive then TLS and LiDAR systems. Data can be output in common data formats, simplifying data processing and management. Measurement points can also be resampled repeatedly throughout the season with high accuracy and precision. Simple trigonometry is used to convert total station measurements into estimates of snow depth perpendicular to the slope. We present results of remote snow depth measurements using a Leica Geosystems TCRP 1201+ robotic total station. Snow depth estimates from the station are validated against measured depths in a field trial. The method is then applied in a basin-scale study to collect and calculate high elevation snow depth, in combination with traditional snow surveys at lower elevations.

  3. Boundary Depth Information Using Hopfield Neural Network

    NASA Astrophysics Data System (ADS)

    Xu, Sheng; Wang, Ruisheng

    2016-06-01

    Depth information is widely used for representation, reconstruction and modeling of 3D scene. Generally two kinds of methods can obtain the depth information. One is to use the distance cues from the depth camera, but the results heavily depend on the device, and the accuracy is degraded greatly when the distance from the object is increased. The other one uses the binocular cues from the matching to obtain the depth information. It is more and more mature and convenient to collect the depth information of different scenes by stereo matching methods. In the objective function, the data term is to ensure that the difference between the matched pixels is small, and the smoothness term is to smooth the neighbors with different disparities. Nonetheless, the smoothness term blurs the boundary depth information of the object which becomes the bottleneck of the stereo matching. This paper proposes a novel energy function for the boundary to keep the discontinuities and uses the Hopfield neural network to solve the optimization. We first extract the region of interest areas which are the boundary pixels in original images. Then, we develop the boundary energy function to calculate the matching cost. At last, we solve the optimization globally by the Hopfield neural network. The Middlebury stereo benchmark is used to test the proposed method, and results show that our boundary depth information is more accurate than other state-of-the-art methods and can be used to optimize the results of other stereo matching methods.

  4. SU-8 based microprobes for simultaneous neural depth recording and drug delivery in the brain.

    PubMed

    Altuna, Ane; Bellistri, Elisa; Cid, Elena; Aivar, Paloma; Gal, Beatriz; Berganzo, Javier; Gabriel, Gemma; Guimerà, Anton; Villa, Rosa; Fernández, Luis J; Menendez de la Prida, Liset

    2013-04-01

    While novel influential concepts in neuroscience bring the focus to local activities generated within a few tens of cubic micrometers in the brain, we are still devoid of appropriate tools to record and manipulate pharmacologically neuronal activity at this fine scale. Here we designed, fabricated and encapsulated microprobes for simultaneous depth recording and drug delivery using exclusively the polymer SU-8 as structural material. A tetrode- and linear-like electrode patterning was combined for the first time with single and double fluidic microchannels for independent drug delivery. The device was tested experimentally using the in vivo anesthetized rat preparation. Both probe types successfully recorded detailed spatiotemporal features of local field potentials and single-cell activity at a resolution never attained before with integrated fluidic probes. Drug delivery was achieved with high spatial and temporal precision in a range from tens of nanoliters to a few microliters, as confirmed histologically. These technological advancements will foster a wide range of neural applications aimed at simultaneous monitoring of brain activity and delivery at a very precise micrometer scale. PMID:23407672

  5. SU-8 based microprobes for simultaneous neural depth recording and drug delivery in the brain.

    PubMed

    Altuna, Ane; Bellistri, Elisa; Cid, Elena; Aivar, Paloma; Gal, Beatriz; Berganzo, Javier; Gabriel, Gemma; Guimerà, Anton; Villa, Rosa; Fernández, Luis J; Menendez de la Prida, Liset

    2013-04-01

    While novel influential concepts in neuroscience bring the focus to local activities generated within a few tens of cubic micrometers in the brain, we are still devoid of appropriate tools to record and manipulate pharmacologically neuronal activity at this fine scale. Here we designed, fabricated and encapsulated microprobes for simultaneous depth recording and drug delivery using exclusively the polymer SU-8 as structural material. A tetrode- and linear-like electrode patterning was combined for the first time with single and double fluidic microchannels for independent drug delivery. The device was tested experimentally using the in vivo anesthetized rat preparation. Both probe types successfully recorded detailed spatiotemporal features of local field potentials and single-cell activity at a resolution never attained before with integrated fluidic probes. Drug delivery was achieved with high spatial and temporal precision in a range from tens of nanoliters to a few microliters, as confirmed histologically. These technological advancements will foster a wide range of neural applications aimed at simultaneous monitoring of brain activity and delivery at a very precise micrometer scale.

  6. Magnetic focusing of an intense slow positron beam for enhanced depth-resolved analysis of thin films and interfaces

    NASA Astrophysics Data System (ADS)

    Falub, C. V.; Eijt, S. W. H.; Mijnarends, P. E.; Schut, H.; van Veen, A.

    2002-08-01

    The intense reactor-based slow positron beam (POSH) at the Delft research reactor has been coupled to a Two-Dimensional Angular Correlation of Annihilation Radiation (2D-ACAR) setup. The design is discussed with a new target chamber for the 2D-ACAR setup based on Monte Carlo simulations of the positron trajectories, beam energy distribution and beam transmission in an increasing magnetic field gradient. Numerical simulations and experiment show that when the slow positron beam with a FWHM of 11.6 mm travels in an increasing axial magnetic field created by a strong NdFeB permanent magnet, the intensity loss is negligible above ˜6 keV and a focusing factor of 5 in diameter is achieved. Monte Carlo simulations and Doppler broadening experiments in the target region show that in this configuration the 2D-ACAR setup can be used to perform depth sensitive studies of defects in thin films with a high resolution. The positron implantation energy can be varied from 0 to 25 keV before entering the non-uniform magnetic field. 2D-ACAR depth-profiling results in He-irradiated Si obtained with the new setup are presented.

  7. High resolution tomographic instrument development

    SciTech Connect

    Not Available

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  8. High resolution tomographic instrument development

    SciTech Connect

    Not Available

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  9. High resolution tomographic instrument development

    NASA Astrophysics Data System (ADS)

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefitted greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  10. Cluster secondary ion mass spectrometry and the temperature dependence of molecular depth profiles.

    PubMed

    Mao, Dan; Wucher, Andreas; Brenes, Daniel A; Lu, Caiyan; Winograd, Nicholas

    2012-05-01

    The quality of molecular depth profiles created by erosion of organic materials by cluster ion beams exhibits a strong dependence upon temperature. To elucidate the fundamental nature of this dependence, we employ the Irganox 3114/1010 organic delta-layer reference material as a model system. This delta-layer system is interrogated using a 40 keV C(60)(+) primary ion beam. Parameters associated with the depth profile such as depth resolution, uniformity of sputtering yield, and topography are evaluated between 90 and 300 K using a unique wedge-crater beveling strategy that allows these parameters to be determined as a function of erosion depth from atomic force microscope (AFM) measurements. The results show that the erosion rate calibration performed using the known Δ-layer depth in connection with the fluence needed to reach the peak of the corresponding secondary ion mass spectrometry (SIMS) signal response is misleading. Moreover, we show that the degradation of depth resolution is linked to a decrease of the average erosion rate and the buildup of surface topography in a thermally activated manner. This underlying process starts to influence the depth profile above a threshold temperature between 210 and 250 K for the system studied here. Below that threshold, the process is inhibited and steady-state conditions are reached with constant erosion rate, depth resolution, and molecular secondary ion signals from both the matrix and the Δ-layers. In particular, the results indicate that further reduction of the temperature below 90 K does not lead to further improvement of the depth profile. Above the threshold, the process becomes stronger at higher temperature, leading to an immediate decrease of the molecular secondary ion signals. This signal decay is most pronounced for the highest m/z ions but is less for the smaller m/z ions, indicating a shift toward small fragments by accumulation of chemical damage. The erosion rate decay and surface roughness buildup

  11. Enhancing sensitivity of high resolution optical coherence tomography using an optional spectrally encoded extended source (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Yu, Xiaojun; Liu, Xinyu; Chen, Si; Wang, Xianghong; Liu, Linbo

    2016-03-01

    High-resolution optical coherence tomography (OCT) is of critical importance to disease diagnosis because it is capable of providing detailed microstructural information of the biological tissues. However, a compromise usually has to be made between its spatial resolutions and sensitivity due to the suboptimal spectral response of the system components, such as the linear camera, the dispersion grating, and the focusing lenses, etc. In this study, we demonstrate an OCT system that achieves both high spatial resolutions and enhanced sensitivity through utilizing a spectrally encoded source. The system achieves a lateral resolution of 3.1 μm and an axial resolution of 2.3 μm in air; when with a simple dispersive prism placed in the infinity space of the sample arm optics, the illumination beam on the sample is transformed into a line source with a visual angle of 10.3 mrad. Such an extended source technique allows a ~4 times larger maximum permissible exposure (MPE) than its point source counterpart, which thus improves the system sensitivity by ~6dB. In addition, the dispersive prism can be conveniently switched to a reflector. Such flexibility helps increase the penetration depth of the system without increasing the complexity of the current point source devices. We conducted experiments to characterize the system's imaging capability using the human fingertip in vivo and the swine eye optic never disc ex vivo. The higher penetration depth of such a system over the conventional point source OCT system is also demonstrated in these two tissues.

  12. Improved tilt-depth method for fast estimation of top and bottom depths of magnetic bodies

    NASA Astrophysics Data System (ADS)

    Wang, Yan-Guo; Zhang, Jin; Ge, Kun-Peng; Chen, Xiao; Nie, Feng-Jun

    2016-06-01

    The tilt-depth method can be used to make fast estimation of the top depth of magnetic bodies. However, it is unable to estimate bottom depths and its every inversion point only has a single solution. In order to resolve such weaknesses, this paper presents an improved tilt-depth method based on the magnetic anomaly expression of vertical contact with a finite depth extent, which can simultaneously estimate top and bottom depths of magnetic bodies. In addition, multiple characteristic points are selected on the tilt angle map for joint computation to improve reliability of inversion solutions. Two- and threedimensional model tests show that this improved tilt-depth method is effective in inverting buried depths of top and bottom bodies, and has a higher inversion precision for top depths than the conventional method. The improved method is then used to process aeromagnetic data over the Changling Fault Depression in the Songliao Basin, and inversion results of top depths are found to be more accurate for actual top depths of volcanic rocks in two nearby drilled wells than those using the conventional tilt-depth method.

  13. Exploratory depth-of-burst experiments

    SciTech Connect

    Reichenbach, H.; Behrens, K.; Kuhl, A.

    1991-12-12

    This report describes the first small-scale explosion experiments with aerated grout (i.e., YTONG). Apart from data referring to crater depth and volume versus depth of burst (DOB), isobaric DOB curves in the range of 1.5 psi {le} p {le} 15 psi were established. The comparison with previous HOB values shows that the ground range to a given overpressure is considerably reduced with increasing depth of burst. The authors plan to continue the airblast investigations with different types of soil materials.

  14. Control of electrode depth in electroslag remelting

    DOEpatents

    Melgaard, David K.; Shelmidine, Gregory J.; Damkroger, Brian K.

    2002-01-01

    A method of and apparatus for controlling an electroslag remelting furnace by driving the electrode at a nominal speed based upon melting rate and geometry while making minor proportional adjustments based on a measured metric of the electrode immersion depth. Electrode drive speed is increased if a measured metric of electrode immersion depth differs from a set point by a predetermined amount, indicating that the tip is too close to the surface of a slag pool. Impedance spikes are monitored to adjust the set point for the metric of electrode immersion depth based upon one or more properties of the impedance spikes.

  15. Improving spatial resolution of confocal Raman microscopy by super-resolution image restoration.

    PubMed

    Cui, Han; Zhao, Weiqian; Wang, Yun; Fan, Ying; Qiu, Lirong; Zhu, Ke

    2016-05-16

    A new super-resolution image restoration confocal Raman microscopy method (SRIR-RAMAN) is proposed for improving the spatial resolution of confocal Raman microscopy. This method can recover the lost high spatial frequency of the confocal Raman microscopy by using Poisson-MAP super-resolution imaging restoration, thereby improving the spatial resolution of confocal Raman microscopy and realizing its super-resolution imaging. Simulation analyses and experimental results indicate that the spatial resolution of SRIR-RAMAN can be improved by 65% to achieve 200 nm with the same confocal Raman microscopy system. This method can provide a new tool for high spatial resolution micro-probe structure detection in physical chemistry, materials science, biomedical science and other areas.

  16. In-vivo high resolution corneal imaging and analysis on animal models for clinical applications

    NASA Astrophysics Data System (ADS)

    Hong, Jesmond; Shinoj, V. K.; Murukeshan, V. M.; Baskaran, M.; Aung, Tin

    2015-07-01

    A simple and low cost optical probe system for the high resolution imaging of the cornea is proposed, based on a Gaussian beam epi-illumination configuration. Corneal topography is obtained by moving the scanning spot across the eye in a raster fashion whereas pachymetry data is achieved by reconstructing the images obtained at different depths. The proposed prototype has been successfully tested on porcine eye samples ex vivo and subsequently on laboratory animals, such as the New Zealand White Rabbit, in vivo. This proposed system and methodology pave the way for realizing a simple and inexpensive optical configuration for pachymetry and keratometry readings, with achievable resolution up to the cellular level. This novel and non-contact high resolution imaging modality demonstrates high intraobserver reproducibility and repeatability. Together with its sophisticated data analysis strategies and safety profile, it is believed to complement existing imaging modalities in the assessment and evaluation of corneal diseases, which enable a decrease in morbidity and improvement in the effectiveness of subsequent treatment.

  17. Achieving closure at Fernald

    SciTech Connect

    Bradburne, John; Patton, Tisha C.

    2001-02-25

    When Fluor Fernald took over the management of the Fernald Environmental Management Project in 1992, the estimated closure date of the site was more than 25 years into the future. Fluor Fernald, in conjunction with DOE-Fernald, introduced the Accelerated Cleanup Plan, which was designed to substantially shorten that schedule and save taxpayers more than $3 billion. The management of Fluor Fernald believes there are three fundamental concerns that must be addressed by any contractor hoping to achieve closure of a site within the DOE complex. They are relationship management, resource management and contract management. Relationship management refers to the interaction between the site and local residents, regulators, union leadership, the workforce at large, the media, and any other interested stakeholder groups. Resource management is of course related to the effective administration of the site knowledge base and the skills of the workforce, the attraction and retention of qualified a nd competent technical personnel, and the best recognition and use of appropriate new technologies. Perhaps most importantly, resource management must also include a plan for survival in a flat-funding environment. Lastly, creative and disciplined contract management will be essential to effecting the closure of any DOE site. Fluor Fernald, together with DOE-Fernald, is breaking new ground in the closure arena, and ''business as usual'' has become a thing of the past. How Fluor Fernald has managed its work at the site over the last eight years, and how it will manage the new site closure contract in the future, will be an integral part of achieving successful closure at Fernald.

  18. Photoacoustic FT-IR depth imaging of polymeric surfaces: overcoming IR diffraction limits.

    PubMed

    Zhang, Ping; Urban, Marek W

    2004-11-23

    It is well established that the photoacoustic effect based on absorption of electromagnetic radiation into thermal waves allows surface depth profiling. However, limited knowledge exists concerning its spatial resolution. The spiral-stepwise (SSW) approach combined with phase rotational analysis is utilized to determine surface depth profiling of homogeneous and nonhomogeneous multilayered polymeric surfaces in a step-scan photoacoustic FT-IR experiment. In this approach, the thermal wave propagating to the surface is represented as the integral of all heat wave vectors propagating across the sampling depth xn, and the spiral function K'beta(lambda)e(-beta)(lambda)xne(-x)n/mu(th)e(i)(omegat-(xn/mu(th))) represents the amplitude and phase of the heat wave vector propagating to the surface. The SSW approach can be applied to heterogeneous surfaces by representing thermal waves propagating to the surface as the sum of the thermal waves propagating through homogeneous layers that are integrals of all heat vectors from a given sampling depth. The proposed model is tested on multilayered polymeric surfaces and shows that the SSW approach allows semiquantitative surface imaging with the spatial resolution ranging from micrometer to 500 nm levels, and the spatial resolution is a function of the penetration depth.

  19. Depth of Monocular Elements in a Binocular Scene: The Conditions for da Vinci Stereopsis

    ERIC Educational Resources Information Center

    Cook, Michael; Gillam, Barbara

    2004-01-01

    Quantitative depth based on binocular resolution of visibility constraints is demonstrated in a novel stereogram representing an object, visible to 1 eye only, and seen through an aperture or camouflaged against a background. The monocular region in the display is attached to the binocular region, so that the stereogram represents an object which…

  20. Classifying depth of anesthesia using EEG features, a comparison.

    PubMed

    Esmaeili, Vahid; Shamsollahi, Mohammad Bagher; Arefian, Noor Mohammad; Assareh, Amin

    2007-01-01

    Various EEG features have been used in depth of anesthesia (DOA) studies. The objective of this study was to find the excellent features or combination of them than can discriminate between different anesthesia states. Conducting a clinical study on 22 patients we could define 4 distinct anesthetic states: awake, moderate, general anesthesia, and isoelectric. We examined features that have been used in earlier studies using single-channel EEG signal processing method. The maximum accuracy (99.02%) achieved using approximate entropy as the feature. Some other features could well discriminate a particular state of anesthesia. We could completely classify the patterns by means of 3 features and Bayesian classifier.