Banning the Bottle

ERIC Educational Resources Information Center

Palliser, Janna

2010-01-01

Bottled water is ubiquitous, taken for granted, and seemingly benign. Americans are consuming bottled water in massive amounts and spending a lot of money: In 2007, Americans spent $11.7 billion on 8.8 billions gallons of bottled water (Gashler 2008). That same year, two million plastic water bottles were used in the United States every five…

Dinucleotide Composition in Animal RNA Viruses Is Shaped More by Virus Family than by Host Species

PubMed Central

Di Giallonardo, Francesca; Schlub, Timothy E.; Shi, Mang

2017-01-01

ABSTRACT Viruses use the cellular machinery of their hosts for replication. It has therefore been proposed that the nucleotide and dinucleotide compositions of viruses should match those of their host species. If this is upheld, it may then be possible to use dinucleotide composition to predict the true host species of viruses sampled in metagenomic surveys. However, it is also clear that different taxonomic groups of viruses tend to have distinctive patterns of dinucleotide composition that may be independent of host species. To determine the relative strength of the effect of host versus virus family in shaping dinucleotide composition, we performed a comparative analysis of 20 RNA virus families from 15 host groupings, spanning two animal phyla and more than 900 virus species. In particular, we determined the odds ratios for the 16 possible dinucleotides and performed a discriminant analysis to evaluate the capability of virus dinucleotide composition to predict the correct virus family or host taxon from which it was isolated. Notably, while 81% of the data analyzed here were predicted to the correct virus family, only 62% of these data were predicted to their correct subphylum/class host and a mere 32% to their correct mammalian order. Similarly, dinucleotide composition has a weak predictive power for different hosts within individual virus families. We therefore conclude that dinucleotide composition is generally uniform within a virus family but less well reflects that of its host species. This has obvious implications for attempts to accurately predict host species from virus genome sequences alone. IMPORTANCE Determining the processes that shape virus genomes is central to understanding virus evolution and emergence. One question of particular importance is why nucleotide and dinucleotide frequencies differ so markedly between viruses. In particular, it is currently unclear whether host species or virus family has the biggest impact on dinucleotide

Dinucleotide Composition in Animal RNA Viruses Is Shaped More by Virus Family than by Host Species.

PubMed

Di Giallonardo, Francesca; Schlub, Timothy E; Shi, Mang; Holmes, Edward C

2017-04-15

Viruses use the cellular machinery of their hosts for replication. It has therefore been proposed that the nucleotide and dinucleotide compositions of viruses should match those of their host species. If this is upheld, it may then be possible to use dinucleotide composition to predict the true host species of viruses sampled in metagenomic surveys. However, it is also clear that different taxonomic groups of viruses tend to have distinctive patterns of dinucleotide composition that may be independent of host species. To determine the relative strength of the effect of host versus virus family in shaping dinucleotide composition, we performed a comparative analysis of 20 RNA virus families from 15 host groupings, spanning two animal phyla and more than 900 virus species. In particular, we determined the odds ratios for the 16 possible dinucleotides and performed a discriminant analysis to evaluate the capability of virus dinucleotide composition to predict the correct virus family or host taxon from which it was isolated. Notably, while 81% of the data analyzed here were predicted to the correct virus family, only 62% of these data were predicted to their correct subphylum/class host and a mere 32% to their correct mammalian order. Similarly, dinucleotide composition has a weak predictive power for different hosts within individual virus families. We therefore conclude that dinucleotide composition is generally uniform within a virus family but less well reflects that of its host species. This has obvious implications for attempts to accurately predict host species from virus genome sequences alone. IMPORTANCE Determining the processes that shape virus genomes is central to understanding virus evolution and emergence. One question of particular importance is why nucleotide and dinucleotide frequencies differ so markedly between viruses. In particular, it is currently unclear whether host species or virus family has the biggest impact on dinucleotide frequencies and

Bottle-brush-shaped heterostructures of NiO-ZnO nanowires: growth study and sensing properties

NASA Astrophysics Data System (ADS)

Baratto, C.; Kumar, R.; Comini, E.; Ferroni, M.; Campanini, M.

2017-11-01

We present here heterostructured ZnO-NiO nanowires (NWs), constituted by a core of single crystalline ZnO NWs, covered by poly-crystalline NiO nanorods (NRs). The bottle-brush shape was investigated by scanning electron microscopy and transmission electron microscope, confirming that a columnar growth of NiO occurred over the ZnO core, with a preferred orientation of NiO over ZnO NWs. The heterostructured devices are proposed for gas sensing application. Bare ZnO NWs and heterostructured sensors with two different thicknesses of NiO poly-crystalline NRs were analysed for acetone, ethanol, NO2 and H2 detection. All sensors maintained n-type sensing mechanism, with improved sensing performance for lower thickness of NiO, due to high catalytic activity of NiO. The sensing dynamic is also strongly modified by the presence of heterojunction of NiO/ZnO, with a reduction of response and recovery times towards ethanol and acetone at 400 °C.

Sulfolobus Spindle-Shaped Virus 1 Contains Glycosylated Capsid Proteins, a Cellular Chromatin Protein, and Host-Derived Lipids

PubMed Central

Quemin, Emmanuelle R. J.; Pietilä, Maija K.; Oksanen, Hanna M.; Forterre, Patrick; Rijpstra, W. Irene C.; Schouten, Stefan; Bamford, Dennis H.; Prangishvili, David

2015-01-01

ABSTRACT Geothermal and hypersaline environments are rich in virus-like particles, among which spindle-shaped morphotypes dominate. Currently, viruses with spindle- or lemon-shaped virions are exclusive to Archaea and belong to two distinct viral families. The larger of the two families, the Fuselloviridae, comprises tail-less, spindle-shaped viruses, which infect hosts from phylogenetically distant archaeal lineages. Sulfolobus spindle-shaped virus 1 (SSV1) is the best known member of the family and was one of the first hyperthermophilic archaeal viruses to be isolated. SSV1 is an attractive model for understanding virus-host interactions in Archaea; however, the constituents and architecture of SSV1 particles remain only partially characterized. Here, we have conducted an extensive biochemical characterization of highly purified SSV1 virions and identified four virus-encoded structural proteins, VP1 to VP4, as well as one DNA-binding protein of cellular origin. The virion proteins VP1, VP3, and VP4 undergo posttranslational modification by glycosylation, seemingly at multiple sites. VP1 is also proteolytically processed. In addition to the viral DNA-binding protein VP2, we show that viral particles contain the Sulfolobus solfataricus chromatin protein Sso7d. Finally, we provide evidence indicating that SSV1 virions contain glycerol dibiphytanyl glycerol tetraether (GDGT) lipids, resolving a long-standing debate on the presence of lipids within SSV1 virions. A comparison of the contents of lipids isolated from the virus and its host cell suggests that GDGTs are acquired by the virus in a selective manner from the host cytoplasmic membrane, likely during progeny egress. IMPORTANCE Although spindle-shaped viruses represent one of the most prominent viral groups in Archaea, structural data on their virion constituents and architecture still are scarce. The comprehensive biochemical characterization of the hyperthermophilic virus SSV1 presented here brings novel and

A pilot study comparing opaque, weighted bottles with conventional, clear bottles for infant feeding

PubMed Central

Ventura, Alison K.; Golen, Rebecca Pollack

2015-01-01

Compared to breast-fed infants, bottle-fed infants consume greater volumes and gain more weight during infancy. It is hypothesized that the visual and weight cues afforded by bottle-feeding may lead mothers to overfeed in response to the amount of liquid in the bottle. The aim of the present pilot study was to test this hypothesis by comparing mothers’ sensitivity and responsiveness to infant cues and infants’ intakes when mothers use opaque, weighted bottles (that remove visual and weight cues) compared to conventional, clear bottles to feed their infants. We also tested the hypothesis that mothers’ pressuring feeding style would moderate the effect of bottle type on mothers’ sensitivity and responsiveness to infant cues and infant intake. Formula-feeding dyads (N=25) visited our laboratory on two separate days. Mothers fed their infants from a clear bottle one day and an opaque, weighted bottle on the other; bottle-order was counterbalanced across the two days. Both bottles were glass with latex, low-flow nipples; the opaque bottle was fitted with a silicone sleeve containing a 60-g metal plate in its base. Infant intake was assessed by weighing each bottle before and after the feeding. Maternal sensitivity and responsiveness to infant cues was objectively assessed using the Nursing Child Assessment Feeding Scale (NCAFS). Mothers were significantly more responsive to infant cues when they used opaque compared to clear bottles (p=.04). There was also a trend for infants to consume significantly less formula when fed from opaque compared to clear bottles (p = .08). Mothers’ pressuring feeding style moderated the effect of bottle type on maternal responsiveness to infant cues (p = .02) and infant intake (p = .03). Specifically, mothers who reported higher levels of pressuring feeding were significantly more responsive to their infants’ cues (p = .02) and fed their infants significantly less formula when using opaque versus clear bottles (p = .01

A pilot study comparing opaque, weighted bottles with conventional, clear bottles for infant feeding.

PubMed

Ventura, Alison K; Pollack Golen, Rebecca

2015-02-01

It is hypothesized that the visual and weight cues afforded by bottle-feeding may lead mothers to overfeed in response to the amount of liquid in the bottle. The aim of the present pilot study was to test this hypothesis by comparing mothers' sensitivity and responsiveness to infant cues and infants' intakes when mothers use opaque, weighted bottles (that remove visual and weight cues) compared to conventional, clear bottles to feed their infants. We also tested the hypothesis that mothers' pressuring feeding style would moderate the effect of bottle type. Formula-feeding dyads (N = 25) visited our laboratory on two separate days. Mothers fed their infants from a clear bottle one day and an opaque, weighted bottle on the other; bottle-order was counterbalanced across the two days. Infant intake was assessed by weighing each bottle before and after the feeding. Maternal sensitivity and responsiveness to infant cues was objectively assessed using the Nursing Child Assessment Feeding Scale. Mothers were significantly more responsive to infant cues when they used opaque compared to clear bottles (p = .04). There was also a trend for infants to consume significantly less formula when fed from opaque compared to clear bottles (p = .08). Mothers' pressuring feeding style moderated the effect of bottle type on maternal responsiveness to infant cues (p = .02) and infant intake (p = .03). Specifically, mothers who reported higher levels of pressuring feeding were significantly more responsive to their infants' cues (p = .02) and fed their infants significantly less formula when using opaque versus clear bottles (p = .01); no differences were seen for mothers who reported lower levels of pressuring feeding. This study highlights a simple, yet effective intervention for improving the bottle-feeding practices of mothers who have pressuring feeding styles. Copyright © 2014 Elsevier Ltd. All rights reserved.

Beverages: bottled water. Final rule.

PubMed

2009-05-29

The Food and Drug Administration (FDA) is amending its bottled water regulations to require that bottled water manufacturers test source water for total coliform, as is required for finished bottled water products, and to require, if any coliform organisms are detected in source water, that bottled water manufacturers determine whether any of the coliform organisms are Escherichia coli (E. coli), an indicator of fecal contamination. FDA also is amending its bottled water regulations to require, if any coliform organisms are detected in finished bottled water products, that bottled water manufacturers determine whether any of the coliform organisms are E. coli. FDA also is amending the adulteration provision of the bottled water standard to reflect the possibility of adulteration caused by the presence of filth. Bottled water containing E. coli will be considered adulterated, and source water containing E. coli will not be considered to be of a safe, sanitary quality and will be prohibited from use in the production of bottled water. FDA is also amending its bottled water regulations to require that, before a bottler can use source water from a source that has tested positive for E. coli, the bottler must take appropriate measures to rectify or eliminate the cause of E. coli contamination of that source, and that the bottler must keep records of such actions. Existing regulatory provisions require bottled water manufacturers to keep records of new testing required by this rule. This final rule will ensure that FDA's standards for the minimum quality of bottled water, as affected by fecal contamination, will be no less protective of the public health than those set by the Environmental Protection Agency (EPA) for public drinking water.

Bottle-feeding histories of preterm infants.

PubMed

Pickler, R H; Mauck, A G; Geldmaker, B

1997-01-01

To describe the bottle-feeding histories of preterm infants and determine physical indices related to and predictive of bottle-feeding initiation and progression. Ex post facto. Academic medical center. A convenience sample of 40 preterm infants without concomitant cardiac, gastrointestinal, or cognitive impairment. Postconceptional age at first bottle-feeding, full bottle-feeding, and discharge. The morbidity rating, using the Neonatal Medical Index (NMI), was most strongly correlated with postconceptional age at first bottle-feeding (r = .34, p < .05), full bottle-feeding (r = .65, p < .01), and discharge (r = .55, p < .05). The morbidity rating also accounted for 12%, 42%, and 30% of the variance in postconceptional age at first bottle-feeding, full bottle-feeding, and discharge, respectively. The NMI may be a useful tool for predicting the initiation and progression of bottle-feeding in preterm infants.

Stopping the Bottle

MedlinePlus

... difficult it can be to break the bottle habit. Longer bottle use may lead to cavities or ... Drinks for Kids Toddlers at the Table: Avoiding Power Struggles View more About Us Contact Us Partners ...

Fluid Dynamics of Bottle Filling

NASA Astrophysics Data System (ADS)

McGough, Patrick; Gao, Haijing; Appathurai, Santosh; Basaran, Osman

2011-11-01

Filling of bottles is a widely practiced operation in a large number of industries. Well known examples include filling of ``large'' bottles with shampoos and cleaners in the household products and beauty care industries and filling of ``small'' bottles in the pharmaceutical industry. Some bottle filling operations have recently drawn much attention from the fluid mechanics community because of the occurrence of a multitude of complex flow regimes, transitions, and instabilities such as mounding and coiling that occur as a bottle is filled with a fluid. In this talk, we present a primarily computational study of the fluid dynamical challenges that can arise during the rapid filling of bottles. Given the diversity of fluids used in filling applications, we consider four representative classes of fluids that exhibit Newtonian, shear-thinning, viscoelastic, and yield-stress rheologies. The equations governing the dynamics of bottle filling are solved either in their full 3D but axisymmetric form or using the slender-jet approximation.

Bottled Water Mania: Americas Misguided Infatuation with Bottled Water over Tap Water

DTIC Science & Technology

2010-05-01

AU/ACSC/BROWN, S/AY10 AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY Bottled Water Mania: America’s Misguided...Infatuation with Bottled Water over Tap Water by Seiho P. Brown, LCDR, U.S. Navy A Research Report Submitted to the Faculty In...iii Abstract The purpose of this paper is to analyze the tendency for American people to drink bottled water over tap water even though it costs

Structural and genomic properties of the hyperthermophilic archaeal virus ATV with an extracellular stage of the reproductive cycle.

PubMed

Prangishvili, David; Vestergaard, Gisle; Häring, Monika; Aramayo, Ricardo; Basta, Tamara; Rachel, Reinhard; Garrett, Roger A

2006-06-23

A novel virus, ATV, of the hyperthermophilic archaeal genus Acidianus has the unique property of undergoing a major morphological development outside of, and independently of, the host cell. Virions are extruded from host cells as lemon-shaped tail-less particles, after which they develop long tails at each pointed end, at temperatures close to that of the natural habitat, 85 degrees C. The extracellularly developed tails constitute tubes, which terminate in an anchor-like structure that is not observed in the tail-less particles. A thin filament is located within the tube, which exhibits a periodic structure. Tail development produces a one half reduction in the volume of the virion, concurrent with a slight expansion of the virion surface. The circular, double-stranded DNA genome contains 62,730 bp and is exceptional for a crenarchaeal virus in that it carries four putative transposable elements as well as genes, which previously have been associated only with archaeal self-transmissable plasmids. In total, it encodes 72 predicted proteins, including 11 structural proteins with molecular masses in the range of 12 to 90 kDa. Several of the larger proteins are rich in coiled coil and/or low complexity sequence domains, which are unusual for archaea. One protein, in particular P800, resembles an intermediate filament protein in its structural properties. It is modified in the two-tailed, but not in the tail-less, virion particles and it may contribute to viral tail development. Exceptionally for a crenarchaeal virus, infection with ATV results either in viral replication and subsequent cell lysis or in conversion of the infected cell to a lysogen. The lysogenic cycle involves integration of the viral genome into the host chromosome, probably facilitated by the virus-encoded integrase and this process can be interrupted by different stress factors.

A three-year clinical evaluation of two-bottle versus one-bottle dentin adhesives.

PubMed

Aw, Tar C; Lepe, Xavier; Johnson, Glen H; Mancl, Lloyd A

2005-03-01

The authors conducted an in vivo investigation to compare the clinical performance of two commercial one-bottle adhesives and a two-bottle adhesive for restoration of noncarious cervical lesions (NCCLs). The patient pool consisted of 57 patients and 171 teeth (three teeth per patient), with one NCCL per tooth. Each patient received three resin-based composite restorations, each with a different adhesive: one tooth with a two-bottle, water-based adhesive as the control; another tooth with a one-bottle, ethanol-based adhesive; and a third tooth with a one-bottle, solvent-free adhesive. The authors assessed restorations in terms of retention, marginal integrity, margin discoloration and air sensitivity at baseline, six months, one year, two years and three years after initial placement. The retention rates at 36 months were 88 percent for the first adhesive, 81 percent for the second adhesive and 90 percent for the third adhesive. No statistically significant differences in retention rates could be shown, with 86 percent of restorations retained overall. Measures of marginal integrity, marginal discoloration and sensitivity also had no statistically significant differences between the three adhesives (P > .05). All three adhesives performed with acceptable outcomes after a 36-month period, with small differences between the one- and two-bottle systems and between the various solvents. Retention rate was moderately high and air sensitivity was markedly reduced; however, superficial marginal discoloration and marginal degradation was notable. Certain lesion, tooth and patient characteristics may predispose restorations to retention failure. The type of solvent may not be a major factor in retention of Class V restorations in NCCLs. Both single-bottle adhesives and conventional two-bottle adhesives performed acceptably.

Post-consumer contamination in high-density polyethylene (HDPE) milk bottles and the design of a bottle-to-bottle recycling process.

PubMed

Welle, F

2005-10-01

Six hundred conventional recycled HDPE flake samples, which were recollected and sorted in the UK, were screened for post-consumer contamination levels. Each analysed sample consisted of 40-50 individual flakes so that the amount of analysed individual containers was in the range 24,000-30,000 post-consumer milk bottles. Predominant contaminants in hot-washed flake samples were unsaturated oligomers, which can be also be found in virgin high-density polyethylene (HDPE) pellet samples used for milk bottle production. In addition, the flavour compound limonene, the degradation product of antioxidant additives di-tert-butylphenol and low amounts of saturated oligomers were found in higher concentrations in the post-consumer samples in comparison with virgin HDPE. However, the overall concentrations in post-consumer recycled samples were similar to or lower than concentration ranges in comparison with virgin HDPE. Contamination with other HDPE untypical compounds was rare and was in most cases related to non-milk bottles, which are <2.1% of the input material of the recycling process. The maximum concentration found in one sample of 1 g was estimated as 130 mg kg(-1), which corresponds to a contamination of 5200-6500 mg kg(-1) in the individual bottle. The recycling process investigated was based on an efficient sorting process, a hot-washing of the ground bottles, and a further deep-cleaning of the flakes with high temperatures and vacuum. Based on the fact that the contamination levels of post-consumer flake samples are similar to virgin HDPE and on the high cleaning efficiency of the super-clean recycling process especially for highly volatile compounds, the recycling process investigated is suitable for recycled post-consumer HDPE bottles for direct food-contact applications. However, hand-picking after automatically sorting is recommended to decrease the amount of non-milk bottles. The conclusions for suitability are valid, provided that the migration testing of

27 CFR 19.382 - Bottling tanks.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottling tanks. 19.382... Manufacture of Articles Bottling, Packaging, and Removal of Products § 19.382 Bottling tanks. All spirits shall be bottled from tanks listed and certified as accurately calibrated in the notice of registration...

27 CFR 4.26 - Estate bottled.

Code of Federal Regulations, 2011 CFR

2011-04-01

... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Standards of Identity for Wine § 4.26 Estate bottled. (a) Conditions for use. The term Estate bottled may be used by a bottling winery on a wine label only if the wine is labeled with a viticultural area appellation of origin and the bottling winery: (1...

27 CFR 4.26 - Estate bottled.

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Standards of Identity for Wine § 4.26 Estate bottled. (a) Conditions for use. The term Estate bottled may be used by a bottling winery on a wine label only if the wine is labeled with a viticultural area appellation of origin and the bottling winery: (1...

The Blue Bottle Revisited.

ERIC Educational Resources Information Center

Vandaveer, Walter R., IV; Mosher, Mel

1997-01-01

Presents a modification of the classic Blue Bottle demonstration that involves the alkaline glucose reduction of methylene blue. Uses other indicators in the classic Blue Bottle to produce a rainbow of colors. (JRH)

Automatic classification of bottles in crates

NASA Astrophysics Data System (ADS)

Aas, Kjersti; Eikvil, Line; Bremnes, Dag; Norbryhn, Andreas

1995-03-01

This paper presents a statistical method for classification of bottles in crates for use in automatic return bottle machines. For the automatons to reimburse the correct deposit, a reliable recognition is important. The images are acquired by a laser range scanner coregistering the distance to the object and the strength of the reflected signal. The objective is to identify the crate and the bottles from a library with a number of legal types. The bottles with significantly different size are separated using quite simple methods, while a more sophisticated recognizer is required to distinguish the more similar bottle types. Good results have been obtained when testing the method developed on bottle types which are difficult to distinguish using simple methods.

An upright eyedrop bottle: accuracy, usage of excess drops, and contamination compared to a conventional bottle.

PubMed

Davies, Isaiah J; Brown, Ninita H; Wen, Joanne C; Stinnett, Sandra S; Kubelick, Kelsey; Patel, Roma P; Benokraitis, Kristin L; Greene, Latoya; Cheek, Curry; Muir, Kelly W

2016-01-01

This study tested the feasibility of using an upright eyedrop bottle (UEB), a device designed to assist patients with eyedrop placement without reclining their head. Experienced eyedrop users were enrolled who answered "yes" to the question, "Do you ever have trouble getting your eyedrops in?" After being shown a multimedia presentation and answering a questionnaire regarding eyedrop usage, participants were observed instilling eyedrops. Participants were instructed to instill a single eyedrop in each eye with both a standard bottle and the UEB. They repeated this process three times. With each trial, the amount of time taken to instill drops was recorded, as well as whether a drop landed in the eye (accuracy), if excess drops were used, and if the bottle tip was contaminated. Forty participants were enrolled, with an average age of 72.4±8.9 years; the majority were females (24 females). Thirty-four participants had been using eyedrops for at least 1 year. The time required to instill eyedrops was significantly less with the UEB in the second and third trials. There was no difference in accuracy between the conventional bottle and the UEB in the left or right eye in any trials. Significantly more participants used excess number of drops while using the conventional bottle in both the left and right eyes in all three trials. The bottle tip was never contaminated with the UEB. Depending on the trial and the eye, the conventional bottle was contaminated by between 42% and 53% of participants. The UEB has the potential to assist patients with eyedrop placement. Although there was no difference in accuracy between the UEB and the conventional bottle, the UEB was associated with less use of excess drops and less contamination of the bottle tip, compared to the conventional bottle.

CHARGE BOTTLE FOR A MASS SEPARATOR

DOEpatents

Davidson, P.H.

1959-07-01

Improved mass separator charge bottles are described for containing a dense charge of a chemical compound of copper, nickel, lead or other useful substance which is to be vaporized, and to the method of utilizing such improvcd charge bottles so that the chemical compound is vaporized from the under surface of the charge and thus permits the non-volatile portion thereof to fall to the bottom of the charge bottle where it does not form an obstacle to further evaporation. The charge bottle comprises a vertically disposed cylindrical portion, an inner re-entrant cylindrical portion extending axially and downwardly into the same from the upper end thereof, and evaporative source material in the form of a chemical compound compacted within the upper annular pontion of the charge bottle formed by the re-entrant cylindrical portion, whereby vapor from the chemical compound will pass outwardly from the charge bottle through an apertured closure.

27 CFR 24.256 - Bottle aging wine.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottle aging wine. 24.256... OF THE TREASURY LIQUORS WINE Storage, Treatment and Finishing of Wine Bottling, Packing, and Labeling of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

21 CFR 165.110 - Bottled water.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... (3) Physical quality. Bottled water shall, when a composite of analytical units of equal volume from.... 1 (4) Chemical quality. (i)(A) Bottled water shall, when a composite of analytical units of equal... bottled water, when a composite of analytical units of equal volume from a sample is examined by the...

27 CFR 19.352 - Bottling tanks.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Bottling tanks. 19.352..., Packaging, and Removal of Products § 19.352 Bottling tanks. Generally, a proprietor must bottle all spirits from tanks that are listed in the notice of registration and have been certified as accurate. However...

27 CFR 19.352 - Bottling tanks.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Bottling tanks. 19.352..., Packaging, and Removal of Products § 19.352 Bottling tanks. Generally, a proprietor must bottle all spirits from tanks that are listed in the notice of registration and have been certified as accurate. However...

27 CFR 19.352 - Bottling tanks.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Bottling tanks. 19.352..., Packaging, and Removal of Products § 19.352 Bottling tanks. Generally, a proprietor must bottle all spirits from tanks that are listed in the notice of registration and have been certified as accurate. However...

27 CFR 19.352 - Bottling tanks.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Bottling tanks. 19.352..., Packaging, and Removal of Products § 19.352 Bottling tanks. Generally, a proprietor must bottle all spirits from tanks that are listed in the notice of registration and have been certified as accurate. However...

21 CFR 868.5220 - Blow bottle.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Blow bottle. 868.5220 Section 868.5220 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5220 Blow bottle. (a) Identification. A blow bottle is a device...

21 CFR 868.5220 - Blow bottle.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Blow bottle. 868.5220 Section 868.5220 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5220 Blow bottle. (a) Identification. A blow bottle is a device...

21 CFR 868.5220 - Blow bottle.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Blow bottle. 868.5220 Section 868.5220 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5220 Blow bottle. (a) Identification. A blow bottle is a device...

21 CFR 868.5220 - Blow bottle.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Blow bottle. 868.5220 Section 868.5220 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5220 Blow bottle. (a) Identification. A blow bottle is a device...

Novel rod-shaped viruses isolated from garlic, Allium sativum, possessing a unique genome organization.

PubMed

Sumi, S; Tsuneyoshi, T; Furutani, H

1993-09-01

Rod-shaped flexuous viruses were partially purified from garlic plants (Allium sativum) showing typical mosaic symptoms. The genome was shown to be composed of RNA with a poly(A) tail of an estimated size of 10 kb as shown by denaturing agarose gel electrophoresis. We constructed cDNA libraries and screened four independent clones, which were designated GV-A, GV-B, GV-C and GV-D, using Northern and Southern blot hybridization. Nucleotide sequence determination of the cDNAs, two of which correspond to nearly one-third of the virus genomic RNA, shows that all of these viruses possess an identical genomic structure and that also at least four proteins are encoded in the viral cDNA, their M(r)s being estimated to be 15K, 27K, 40K and 11K. The 15K open reading frame (ORF) encodes the core-like sequence of a zinc finger protein preceded by a cluster of basic amino acid residues. The 27K ORF probably encodes the viral coat protein (CP), based on both the existence of some conserved sequences observed in many other rod-shaped or flexuous virus CPs and an overall amino acid sequence similarity to potexvirus and carlavirus CPs. The 11K ORF shows significant amino acid sequence similarities to the corresponding 12K proteins of the potexviruses and carlaviruses. On the other hand, the 40K ORF product does not resemble any other plant virus gene products reported so far. The genomic organization in the 3' region of the garlic viruses resembles, but clearly differs from, that of carlaviruses. Phylogenetic analysis based upon the amino acid sequence of the viral capsid protein also indicates that the garlic viruses have a unique and distinct domain different from those of the potexvirus and carlavirus groups. The results suggest that the garlic viruses described here belong to an unclassified and new virus group closely related to the carlaviruses.

Health beliefs about bottled water: a qualitative study.

PubMed

Ward, Lorna A; Cain, Owen L; Mullally, Ryan A; Holliday, Kathryn S; Wernham, Aaron G H; Baillie, Paul D; Greenfield, Sheila M

2009-06-19

There has been a consistent rise in bottled water consumption over the last decade. Little is known about the health beliefs held by the general public about bottled water as this issue is not addressed by the existing quantitative literature. The purpose of this study was to improve understanding of the public's health beliefs concerning bottled mineral water, and the extent to which these beliefs and other views they hold, influence drinking habits. A qualitative study using semi-structured interviews, with 23 users of the Munrow Sports Centre on the University of Birmingham campus. Health beliefs about bottled water could be classified as general or specific beliefs. Most participants believed that bottled water conferred general health benefits but were unsure as to the nature of these. In terms of specific health beliefs, the idea that the minerals in bottled water conferred a health benefit was the most commonly cited. There were concerns over links between the plastic bottle itself and cancer. Participants believed that bottled water has a detrimental effect on the environment. Convenience, cost and taste were influential factors when making decisions as to whether to buy bottled water; health beliefs were unimportant motivating factors. The majority of participants believed that bottled water has some health benefits. However, these beliefs played a minor role in determining bottled water consumption and are unlikely to be helpful in explaining recent trends in bottled water consumption if generalised to the UK population. The health beliefs elicited were supported by scientific evidence to varying extents. Most participants did not feel that bottled water conferred significant, if any, health benefits over tap water.

Health beliefs about bottled water: a qualitative study

PubMed Central

Ward, Lorna A; Cain, Owen L; Mullally, Ryan A; Holliday, Kathryn S; Wernham, Aaron GH; Baillie, Paul D; Greenfield, Sheila M

2009-01-01

Background There has been a consistent rise in bottled water consumption over the last decade. Little is known about the health beliefs held by the general public about bottled water as this issue is not addressed by the existing quantitative literature. The purpose of this study was to improve understanding of the public's health beliefs concerning bottled mineral water, and the extent to which these beliefs and other views they hold, influence drinking habits. Methods A qualitative study using semi-structured interviews, with 23 users of the Munrow Sports Centre on the University of Birmingham campus. Results Health beliefs about bottled water could be classified as general or specific beliefs. Most participants believed that bottled water conferred general health benefits but were unsure as to the nature of these. In terms of specific health beliefs, the idea that the minerals in bottled water conferred a health benefit was the most commonly cited. There were concerns over links between the plastic bottle itself and cancer. Participants believed that bottled water has a detrimental effect on the environment. Convenience, cost and taste were influential factors when making decisions as to whether to buy bottled water; health beliefs were unimportant motivating factors. Conclusion The majority of participants believed that bottled water has some health benefits. However, these beliefs played a minor role in determining bottled water consumption and are unlikely to be helpful in explaining recent trends in bottled water consumption if generalised to the UK population. The health beliefs elicited were supported by scientific evidence to varying extents. Most participants did not feel that bottled water conferred significant, if any, health benefits over tap water. PMID:19545357

Oscillations in a half-empty bottle

NASA Astrophysics Data System (ADS)

Bourges, Andréane; Chardac, Amélie; Caussarieu, Aude; Plihon, Nicolas; Taberlet, Nicolas

2018-02-01

When a half-empty bottle of water is pushed to roll on a flat surface, the oscillations of the fluid inside the bottle induce an overall jerky motion. These velocity fluctuations of the bottle are studied through simple laboratory experiments accessible to undergraduate students and can help them to grasp fundamental concepts in mechanics and hydrodynamics. We first demonstrate through an astute experiment that the rotation of the fluid and the bottle is decoupled. The equations of motion are then derived using a mechanical approach, while the hydrodynamics of the fluid motion is explained. Finally, the theory is tested against two benchmark experiments.

The bottle gourd genome provides insights into Cucurbitaceae evolution and facilitates mapping of a Papaya ringspot virus resistance locus

USDA-ARS?s Scientific Manuscript database

Bottle gourd (Lagenaria siceraria) is an important vegetable crop as well as a rootstock for other cucurbit crops. In this study, we report a high-quality 313.4-Mb genome sequence of a bottle gourd inbred line, USVL1VR-Ls, with a scaffold N50 of 8.7 Mb and the longest of 19.0 Mb. About 98.3% of the ...

Mouse taste preference tests: why only two bottles?

PubMed

Tordoff, Michael G; Bachmanov, Alexander A

2003-05-01

Two-bottle tests have been used extensively to measure the preference for taste and nutrient solutions but there has been little work with tests involving more than two bottles. Here, we compare the results obtained in two-bottle tests with those obtained in three- and six-bottle tests. In Experiment 1, we measured the preferences for 2 mM saccharin, 50 mM citric acid, 0.3 mM quinine hydrochloride and 75 mM NaCl displayed by 129X1/SvJ (129) and C57BL/6J (B6) mice. Mice drank more taste solution when they received two bottles providing taste solution and one providing water than when they received either a standard two-bottle test or two bottles providing water and one providing taste solution. The three-bottle tests also revealed the left spout side preferences of the 129 strain and were generally better at distinguishing between the 129 and B6 strains (i.e. were more sensitive) than were the two-bottle tests. In Experiment 2, we measured intakes and preferences in tests with six bottles, with one, two, three, four or five containing 75 mM NaCl and the rest containing water. NaCl preferences were monotonically related to the number of NaCl spouts available. A follow-up experiment found similar results whether the index of ingestion was volume intakes or licks. This argues that spillage cannot account for the effect of spout number on taste solution intake. Together, the results suggest that (i) the number of bottles of taste solution and water has a profound influence on taste solution intake and preference, and (ii) three-bottle tests may be more sensitive than two-bottle tests in many circumstances.

Mouse Taste Preference Tests: Why Only Two Bottles?

PubMed Central

Tordoff, Michael G.; Bachmanov, Alexander A.

2008-01-01

Two-bottle tests have been used extensively to measure the preference for taste and nutrient solutions but there has been little work with tests involving more than two bottles. Here, we compare the results obtained in two-bottle tests with those obtained in three- and six-bottle tests. In Experiment 1, we measured the preferences for 2 mM saccharin, 50 mM citric acid, 0.3 mM quinine hydrochloride and 75 mM NaCl displayed by 129X1/SvJ (129) and C57BL/6J (B6) mice. Mice drank more taste solution when they received two bottles providing taste solution and one providing water than when they received either a standard two-bottle test or two bottles providing water and one providing taste solution. The three-bottle tests also revealed the left spout side preferences of the 129 strain and were generally better at distinguishing between the 129 and B6 strains (i.e. were more sensitive) than were the two-bottle tests. In Experiment 2, we measured intakes and preferences in tests with six bottles, with one, two, three, four or five containing 75 mM NaCl and the rest containing water. NaCl preferences were monotonically related to the number of NaCl spouts available. A follow-up experiment found similar results whether the index of ingestion was volume intakes or licks. This argues that spillage cannot account for the effect of spout number on taste solution intake. Together, the results suggest that (i) the number of bottles of taste solution and water has a profound influence on taste solution intake and preference, and (ii) three-bottle tests may be more sensitive than two-bottle tests in many circumstances. PMID:12771018

27 CFR 25.142 - Bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.142 Bottles. (a) Label requirements. Each bottle of... brewer's name, trade name or brand name includes the name of a city which is not the place where the beer...

Phthalates residues in plastic bottled waters.

PubMed

Al-Saleh, Iman; Shinwari, Neptune; Alsabbaheen, Ammar

2011-08-01

This study was conducted to determine the presence of phthalates in 10 different brands of bottled water available in Saudi markets and stored under different conditions. Dimethyl phthalate (DMP), diethylphthalate (DEP), di-n-butyl phthalate (DBP), benzyl butyl phthalate (BBP) and diethyl hexyl phthalate (DEHP) were measured by headspace solid-phase microextraction followed by gas chromatography- mass spectrometer detector. Most of these phthalates were detected in the selected bottled water sample that might be either leached from the plastic packaging materials or contamination during bottling processes. Bottled waters stored at 4°C contained higher levels of DMP, DEP, BBP and DEHP than those stored at room temperature and outdoors. On the other hand, the levels of DMP, DEP and BBP were significantly lower in bottled waters stored at room temperature than those outdoor. It seems that temperature and sunlight play a role in the degradation of phthalates within time. The levels of BBP were the highest at 4°C storage (4.592 ± 3.081 µg/l; range: 1.194-21.128 µg/l) and approximately 76% of the bottled waters had BBP above the limit of quantification (LOQ) of 0.994 µg/l. Apart from DEHP (< 6 µg/l), there are not current legislations for other phthalates. Regardless of storage conditions, all our samples did not exceed the maximum established limit of DEHP. Although, the levels of phthalates in tested bottled waters were low, one should not dismiss that these chemicals may cause endocrine disruption through several mechanisms, especially to potentially vulnerable populations such as infants and pregnant women. Saudi Arabia ranks 12 in bottled water consumption (88 L per capita in 2004) among the 71 reported countries. With this high consumption, a quality assurance scheme for residue monitoring in water is quite important. Although, one cannot avoid phthalates contamination in bottled waters due to manufacturing process but at least special care should be taken

Determinants of bottle use amongst economically disadvantaged mothers.

PubMed

Shamim, Samina; Jamalvi, S Waseem; Naz, Farah

2006-01-01

There is documented evidence of increased risk of infant mortality in formula fed infants versus breast fed babies. The hazards of bottle use for infant feeding, especially in underprivileged communities, are also well known. As the issue of bottle use is directly related to childhood survival and mortality, there is legislation against propagation of bottle-feeding in Pakistan. To obtain information about determinants of bottle use for infant feeding in a low-income periurban community. Community based cross-sectional study. 150 mothers with infants up to one year of age were included in the study period from October 03 to March 04. Out of these 102 mothers were found using bottle for infant with or without breast-feeding. The tendency to use the bottle increased in relation to child's increasing age. Only 17% of the infants under the age of 3 months were offered bottle, it was 69% between 4 to 6 months and it increased to 76% in infants from 7 months to 1 year. The attributes associated with increased bottle use were mother's older age, illiteracy and increased parity. Bottle use is a public health issue in poor and illiterate mothers of developing countries. While, in Pakistan, laws are enacted against its propagation, we need community-based strategies to bring about a socio-cultural shift in the growing prevalence of bottle use found in the study.

Running Mechanics and Metabolic Responses with Water Bottles and Bottle Belt Holders.

PubMed

Vincent, Heather K; Zdziarski, Laura A; Fallgatter, Kyle; Negron, Giorgio; Chen, Cong; Leavitt, Trevor; Horodyski, MaryBeth; Wasser, Joseph G; Vincent, Kevin R

2018-01-18

This study determined whether differential kinematics, kinetics, rates of energy use and cardiopulmonary responses occurred during running with water bottles and bottle belt holders compared to running only. Trained runners (N=42; 27.2±6.4 yr) ran on an instrumented treadmill for four conditions in a randomized order: 1) control run (CON); 2) hand-held full water bottle (FULL, 16.9 fluid oz; 454 g); 3) hand-held half-full water bottle (HALF, 8.4 fluid oz.; 227 g); and 4) waist-worn bottle belt holder (BELT; hydration belt; 676 g). Gas exchange was measured using a portable gas analyzer. Kinetic and kinematic responses were determined via standard 3D videographic techniques. Interactions of limb side (right, left) by study condition (CON, FULL, HALF, BELT) were tested for rates of oxygen use and energy expenditure, and kinematic and kinetic parameters. No significant limb side × condition interactions existed for rates of oxygen use or energy expenditure. A significant interaction occurred with sagittal elbow flexion (p<0.001). Transverse pelvis rotation excursions differed on average 3.8° across conditions. The minimum sagittal hip flexion moment was higher in the right leg in the HALF and BELT conditions compared to CON (p<0.001). Carriage of water by hand or on the waist does not significantly change kinematics of running motion, rates of oxygen use and energy expenditure or cardiopulmonary measures over short durations. Runners are likely making adjustments to joint moments and powers that preserve balance and protect the lower extremity joints while maintaining the rates of oxygen use and energy expenditure.

Fluoride content of still bottled water in Australia.

PubMed

Cochrane, N J; Saranathan, S; Morgan, M V; Dashper, S G

2006-09-01

Recently there has been a considerable increase in the consumption of bottled water in Australia. Overseas studies have found the fluoride levels in many bottled waters are well below levels considered optimal for preventing dental caries. This raises the concern that if bottled water is regularly consumed an effective means of preventing dental caries is unavailable. The aim of this study was to determine the fluoride concentration in 10 popular brands of still bottled water currently sold in Australia. The fluoride content of water samples were determined using an ion analyser and compared to a fluoride standard. The fluoride concentration of all bottled waters was less than 0.08 ppm. Only three of the 10 brands indicated the fluoride content on their labels. Melbourne reticulated water was found to be fluoridated at 1.02 ppm. All bottled waters tested contained negligible fluoride which justifies the concern that regular consumption of bottled water may reduce the benefits gained from water fluoridation. It is recommended that all bottled water companies should consider stating their fluoride content on their labels. This will inform consumers and dental care providers of the levels of fluoride in bottled water and allow an informed decision regarding consumption of fluoridated versus non-fluoridated drinking water.

Extreme Mutation Tolerance: Nearly Half of the Archaeal Fusellovirus Sulfolobus Spindle-Shaped Virus 1 Genes Are Not Required for Virus Function, Including the Minor Capsid Protein Gene vp3

PubMed Central

Iverson, Eric A.; Goodman, David A.; Gorchels, Madeline E.

2017-01-01

ABSTRACT Viruses infecting the Archaea harbor a tremendous amount of genetic diversity. This is especially true for the spindle-shaped viruses of the family Fuselloviridae, where >90% of the viral genes do not have detectable homologs in public databases. This significantly limits our ability to elucidate the role of viral proteins in the infection cycle. To address this, we have developed genetic techniques to study the well-characterized fusellovirus Sulfolobus spindle-shaped virus 1 (SSV1), which infects Sulfolobus solfataricus in volcanic hot springs at 80°C and pH 3. Here, we present a new comparative genome analysis and a thorough genetic analysis of SSV1 using both specific and random mutagenesis and thereby generate mutations in all open reading frames. We demonstrate that almost half of the SSV1 genes are not essential for infectivity, and the requirement for a particular gene correlates well with its degree of conservation within the Fuselloviridae. The major capsid gene vp1 is essential for SSV1 infectivity. However, the universally conserved minor capsid gene vp3 could be deleted without a loss in infectivity and results in virions with abnormal morphology. IMPORTANCE Most of the putative genes in the spindle-shaped archaeal hyperthermophile fuselloviruses have no sequences that are clearly similar to characterized genes. In order to determine which of these SSV genes are important for function, we disrupted all of the putative genes in the prototypical fusellovirus, SSV1. Surprisingly, about half of the genes could be disrupted without destroying virus function. Even deletions of one of the known structural protein genes that is present in all known fuselloviruses, vp3, allows the production of infectious viruses. However, viruses lacking vp3 have abnormal shapes, indicating that the vp3 gene is important for virus structure. Identification of essential genes will allow focused research on minimal SSV genomes and further understanding of the structure

Extreme Mutation Tolerance: Nearly Half of the Archaeal Fusellovirus Sulfolobus Spindle-Shaped Virus 1 Genes Are Not Required for Virus Function, Including the Minor Capsid Protein Gene vp3.

PubMed

Iverson, Eric A; Goodman, David A; Gorchels, Madeline E; Stedman, Kenneth M

2017-05-15

Viruses infecting the Archaea harbor a tremendous amount of genetic diversity. This is especially true for the spindle-shaped viruses of the family Fuselloviridae , where >90% of the viral genes do not have detectable homologs in public databases. This significantly limits our ability to elucidate the role of viral proteins in the infection cycle. To address this, we have developed genetic techniques to study the well-characterized fusellovirus Sulfolobus spindle-shaped virus 1 (SSV1), which infects Sulfolobus solfataricus in volcanic hot springs at 80°C and pH 3. Here, we present a new comparative genome analysis and a thorough genetic analysis of SSV1 using both specific and random mutagenesis and thereby generate mutations in all open reading frames. We demonstrate that almost half of the SSV1 genes are not essential for infectivity, and the requirement for a particular gene correlates well with its degree of conservation within the Fuselloviridae The major capsid gene vp1 is essential for SSV1 infectivity. However, the universally conserved minor capsid gene vp3 could be deleted without a loss in infectivity and results in virions with abnormal morphology. IMPORTANCE Most of the putative genes in the spindle-shaped archaeal hyperthermophile fuselloviruses have no sequences that are clearly similar to characterized genes. In order to determine which of these SSV genes are important for function, we disrupted all of the putative genes in the prototypical fusellovirus, SSV1. Surprisingly, about half of the genes could be disrupted without destroying virus function. Even deletions of one of the known structural protein genes that is present in all known fuselloviruses, vp3 , allows the production of infectious viruses. However, viruses lacking vp3 have abnormal shapes, indicating that the vp3 gene is important for virus structure. Identification of essential genes will allow focused research on minimal SSV genomes and further understanding of the structure of

A descriptive study of bottle-feeding opportunities in preterm infants.

PubMed

Pickler, Rita H; Reyna, Barbara A

2003-06-01

The purposes of this study were to describe patterns of bottle feeding opportunities in preterm infants and to analyze the relationships between feeding opportunities and outcomes. The smaple was composed of 25 preterm infants who were bottle fed. Retrospective, correlational. Data were collected from medical records and analyzed descriptively. Correlation coefficients among variables were computed. Postconceptional age (PCA) at the time of full bottle feedings and transition time from the first to full bottle feedings. The number of bottle feedings received per day during the transition from first to full bottle feedings was inversely related to length of transition to full bottle feedings. There was no relationship between the number of bottle-feeding opportunities and PCA at full bottle feedings. The achievement of full bottle feedings may be facilitated by increased bottle-feeding opportunities. More research about the relationships among feeding readiness, outcomes, and opportunities is needed.

Bottle appeal drifts across the Pacific

NASA Astrophysics Data System (ADS)

Ebbesmeyer, Curtis; Ingraham, W. James, Jr.; McKinnon, Richard; Okubo, Akira; Wang, Dong-Ping; Strickland, Richard; Willing, Peter

Pacific drift currents were used by a group of oceanographers to estimate the path of a drift bottle that was found on a beach of Barkley Sound in Vancouver Island by Richard Strickland on June 10, 1990. The Chinese rice wine bottle, which remained unopened until December 18, 1991, contained six leaflets, one appealing for the release of China's well-known dissident, Wei Jingsheng. The bottle was one of thousands set adrift as part of a propaganda effort from the islands of Quemoy and Matsu off mainland China shortly after Wei was sentenced in 1979 to 15 years in prison (see Figure 1 for locations). Wei was in poor health and still in prison when the bottle made its way across the Pacific Ocean.

27 CFR 24.256 - Bottle aging wine.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

27 CFR 24.256 - Bottle aging wine.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

27 CFR 24.256 - Bottle aging wine.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

27 CFR 24.256 - Bottle aging wine.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Bottle aging wine. 24.256 Section 24.256 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of Wine § 24.256 Bottle aging wine. Wine bottled or packed and stored for the purpose of aging need...

27 CFR 31.201 - Refilling of liquor bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Bottles § 31.201 Refilling of liquor bottles. No person who sells, or offers for sale, distilled spirits... or increase any portion of the original contents contained in that bottle at the time of closing...

27 CFR 24.308 - Bottled or packed wine record.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottled or packed wine... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Records and Reports § 24.308 Bottled or packed wine record. A proprietor who bottles, packs, or receives bottled or packed beverage wine in bond shall...

Buying and Caring for Baby Bottles and Nipples

MedlinePlus

... will not break if dropped. If you choose plastic, it is best to buy new bottles. Reused or hand-me-down bottles may contain bisphenol-A (BPA). The Food and Drug Administration (FDA) has banned the use of BPA in baby bottles due to safety ...

Formalin-inactivated Venezuelan Equine Encephalomyelitis (Trinidad Strain) Vaccine Produced in Rolling-Bottle Cultures of Chicken Embryo Cells

PubMed Central

Cole, Francis E.; May, Stephen W.; Robinson, David M.

1973-01-01

Formalin-inactivated Venezuelan equine encephalomyelitis vaccine was prepared from virus grown in rolling-bottle cultures of chicken embryo cells. Trinidad strain virus was propagated in these cultures with a maintenance medium consisting of serum-free medium 199 containing 0.25% human serum albumin (USP) and antibiotics. Manipulation of multiplicity of inoculum (0.06 to 0.00006) and maintenance medium volume (100 to 300 ml) resulted in high-titered virus yields and only moderate cell destruction when fluids from infected cultures were harvested at 18 to 24 hr. The virus was inactivated at 37 C by 0.05% Formalin within 8 to 10 hr and with 0.1% Formalin within 6 to 8 hr. Single dose, antigen extinction tests in mice performed with 30 small-scale vaccine lots showed excellent potency at either Formalin concentration with inactivation periods ranging from 24 to 96 hr. PMID:4694345

27 CFR 19.749 - Bottling and packaging record.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottling and packaging record. 19.749 Section 19.749 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Account § 19.749 Bottling and packaging record. The bottling and packaging record shall be prepared and...

Bottle Biology.

ERIC Educational Resources Information Center

Jager, Peter

1993-01-01

Describes activities which utilize plastic drink bottles and are designed to foster the development of a wide range of biological and ecological concepts. Includes instructions for making a model compost column and presents a model that illustrates open versus closed ecosystems. (DDR)

27 CFR 31.202 - Possession of refilled liquor bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Liquor Bottles § 31.202 Possession of refilled liquor bottles. No person who sells, or offers for sale... bottle, any portion of the contents of which has been altered or increased in violation of the provisions...

Small-sized microplastics and pigmented particles in bottled mineral water.

PubMed

Oßmann, Barbara E; Sarau, George; Holtmannspötter, Heinrich; Pischetsrieder, Monika; Christiansen, Silke H; Dicke, Wilhelm

2018-09-15

Up to now, only a few studies about microparticle contamination of bottled mineral water have been published. The smallest analysed particle size was 5 μm. However, due to toxicological reasons, especially microparticles smaller than 1.5 μm are critically discussed. Therefore, in the present study, 32 samples of bottled mineral water were investigated for contamination by microplastics, pigment and additive particles. Due to the application of aluminium coated polycarbonate membrane filters and micro-Raman spectroscopy, a lowest analysed particle size of 1 μm was achieved. Microplastics were found in water from all bottle types: in single use and reusable bottles made of poly(ethylene terephthalate) (PET) as well as in glass bottles. The amount of microplastics in mineral water varied from 2649 ± 2857 per litre in single use PET bottles up to 6292 ± 10521 per litre in glass bottles. While in plastic bottles, the predominant polymer type was PET; in glass bottles various polymers such as polyethylene or styrene-butadiene-copolymer were found. Hence, besides the packaging itself, other contamination sources have to be considered. Pigment particles were detected in high amounts in reusable, paper labelled bottles (195047 ± 330810 pigment particles per litre in glass and 23594 ± 25518 pigment particles per litre in reusable paper labelled PET bottles). Pigment types found in water samples were the same as used for label printing, indicating the bottle cleaning process as possible contamination route. Furthermore, on average 708 ± 1024 particles per litre of the additive Tris(2,4-di-tert-butylphenyl)phosphite were found in reusable PET bottles. This additive might be leached out from the bottle material itself. Over 90% of the detected microplastics and pigment particles were smaller than 5 μm and thus not covered by previous studies. In summary, this is the first study reporting about microplastics, pigment and additive particles

Distinct symmetry and limited peptide refolding activity of the thermosomes from the acidothermophilic archaea Acidianus tengchongensis S5{sup T}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Li; Hu, Zhong-jun; Luo, Yuan-ming

Recombinant thermosomes from the Acidianus tengchongensis strain S5{sup T} were purified to homogeneity and assembled in vitro into homo-oligomers (rATcpn{alpha} or rATcpn{beta}) and hetero-oligomers (rATcpn{alpha}{beta}). The symmetries of these complexes were determined by electron microscopy and image analysis. The rATcpn{alpha} homo-oligomer was shown to possess 8-fold symmetry while both rATcpn{beta} and rATcpn{alpha}{beta} oligomers adopted 9-fold symmetry. rATcpn{alpha}{beta} oligomers were shown to contain the {alpha} and {beta} subunits in a 1:2 ratio. All of the complexes prevented the irreversible inactivation of yeast alcohol dehydrogenase at 55 {sup o}C and completely prevented the formation of aggregates during thermal inactivation of citrate synthasemore » at 45 {sup o}C. All rATcpn complexes showed trace ATP hydrolysis activity. Furthermore, rATcpn{beta} sequestered fully chemically denatured substrates (GFP and thermophilic malic dehydrogenase) in vitro without refolding them in an ATP-dependent manner. This property is similar to previously reported properties of chaperonins from Sulfolobus tokodaii and Sulfolobus acidocaldarius. These features are consistent with the slow growth rates of these species of archaea in their native environment.« less

27 CFR 31.232 - Wine bottling.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... The decanting of wine by caterers or other retail dealers for table or room service, banquets, and... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Wine bottling. 31.232... OF THE TREASURY LIQUORS ALCOHOL BEVERAGE DEALERS Miscellaneous § 31.232 Wine bottling. Each person...

21 CFR 165.110 - Bottled water.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., when a composite of analytical units of equal volume from a sample is examined by the method described...)(A) Bottled water shall, when a composite of analytical units of equal volume from a sample is..., and Cosmetic Act, the Food and Drug Administration has determined that bottled water, when a composite...

21 CFR 880.6085 - Hot/cold water bottle.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

21 CFR 880.6085 - Hot/cold water bottle.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

21 CFR 880.6085 - Hot/cold water bottle.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

21 CFR 880.6085 - Hot/cold water bottle.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

21 CFR 880.6085 - Hot/cold water bottle.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

Does a time constraint modify results from rating-based conjoint analysis? Case study with orange/pomegranate juice bottles.

PubMed

Reis, Felipe; Machín, Leandro; Rosenthal, Amauri; Deliza, Rosires; Ares, Gastón

2016-12-01

People do not usually process all the available information on packages for making their food choices and rely on heuristics for making their decisions, particularly when having limited time. However, in most consumer studies encourage participants to invest a lot of time for making their choices. Therefore, imposing a time-constraint in consumer studies may increase their ecological validity. In this context, the aim of the present work was to evaluate the influence of a time-constraint on consumer evaluation of pomegranate/orange juice bottles using rating-based conjoint task. A consumer study with 100 participants was carried out, in which they had to evaluate 16 pomegranate/orange fruit juice bottles, differing in bottle design, front-of-pack nutritional information, nutrition claim and processing claim, and to rate their intention to purchase. Half of the participants evaluated the bottle images without time constraint and the other half had a time-constraint of 3s for evaluating each image. Eye-movements were recorded during the evaluation. Results showed that time-constraint when evaluating intention to purchase did not largely modify the way in which consumers visually processed bottle images. Regardless of the experimental condition (with or without time constraint), they tended to evaluate the same product characteristics and to give them the same relative importance. However, a trend towards a more superficial evaluation of the bottles that skipped complex information was observed. Regarding the influence of product characteristics on consumer intention to purchase, bottle design was the variable with the largest relative importance in both conditions, overriding the influence of nutritional or processing characteristics, which stresses the importance of graphic design in shaping consumer perception. Copyright © 2016 Elsevier Ltd. All rights reserved.

Physical, chemical and microbial analysis of bottled drinking water.

PubMed

Sasikaran, S; Sritharan, K; Balakumar, S; Arasaratnam, V

2012-09-01

People rely on the quality of the bottled drinking water, expecting it to be free of microbial contamination and health hazards. To evaluate the quality of bottled drinking water sold in Jaffna peninsula by analysing the physical, chemical and microbial contents and comparing with the recommended Sri Lankan Standard (SLS) values. All bottled water samples sold in Jaffna peninsula were collected. Electrical conductivity, total dissolved solid, pH, calcium, nitrate, total aerobic and anaerobic count, coliform bacterial count and faecal contamination were checked. These are 22 brands of bottled drinking water sold in Jaffna peninsula. The sample had very low electrical conductivity when compared with SLS (750 μS/ cm) and varied from 19 to 253 μS/cm with the mean of 80.53 (±60.92) μS/cm. The pH values of the bottled drinking water brands varied from 4.11 to 7.58 with a mean of 6.2 (±0.75). The total dissolved solid content of the bottled drinking water brands varied from 9 to 123.67 mg/l with a mean of 39.5 (±30.23) mg/l. The calcium content of the bottled drinking water brands varied from 6.48 to 83.77 mg/l with a mean of 49.9 (±25.09) mg/l. The nitrate content of the bottled drinking water brands varied from 0.21 to 4.19 mg/l with the mean of 1.26 (±1.08) mg/l. Aerobic bacterial count varied from 0 to 800 colony forming unit per ml (cfu/ml) with a mean of 262.6 (±327.50) cfu/ml. Among the 22 drinking bottled water brands 14 and 9% of bottled drinking water brands showed fungal and coliform bacterial contaminants respectively. The water brands which contained faecal contamination had either Escherichia coli or Klebsiella spp. The bottled drinking water available for sale do not meet the standards stipulated by SLS.

Bottle-feeding legislation in Papua New Guinea.

PubMed

Lambert, J

1980-02-01

Research in Papua New Guinea and elsewhere in the developing world has indicted the dangers of bottle feeding infants. Following a failure to obtain the voluntary agreement of shopkeepers to restrict sales of infant-feeding bottles and teats, legislation was passed which placed these items on prescription. In order to obtain a prescription certain conditions have to be satisfied. A follow-up survey which was carried out in Port Moresby two years after the introduction of legislation indicated a significant decline in the extent of bottle feeding.

Simultaneous determination and assessment of 4-nonylphenol, bisphenol A and triclosan in tap water, bottled water and baby bottles.

PubMed

Li, Xu; Ying, Guang-Guo; Su, Hao-Chang; Yang, Xiao-Bing; Wang, Li

2010-08-01

This study investigated the levels of 4-nonylphenol (4-NP), bisphenol A (BPA) and triclosan (TCS) in bottled water and tap water in Guangzhou and release of these chemicals from baby bottles using gas chromatography-mass spectrometry with negative chemical ionization. Results show that 4-NP was present in all the bottled water while 17 out of 21 contained BPA and 18 out of 21 contained TCS. Their concentrations in bottled water ranged from 108 to 298 ng/L, 17.6 to 324 ng/L and 0.6 to 9.7 ng/L, respectively. Five of the tap water samples from six drinking water plants were found to contain 4-NP and BPA both in June and December, while TCS was detected in the same five plants only in June. The highest concentrations in tap water for 4-NP, BPA and TCS were 1987, 317 and 14.5ng/L, respectively. Daily intakes of 4-NP, BPA and TCS of adults by drinking 2L of tap water were estimated to be 1410, 148 and 10 ng/day, respectively. BPA was found to be released within 24h from four brands of baby bottles at room temperature (24 degrees C), 40 degrees C and 100 degrees C. Increased temperature led to higher release of BPA from the baby bottles. Estimated daily intakes of 4-NP, BPA and TCS for infants were 705, 1340 and 5 ng/day, respectively, by drinking 1L of tap water from a baby bottle at 40 degrees C. This study showed that the exposure to the three compounds from drinking water is unlikely to pose a health risk. Copyright 2010 Elsevier Ltd. All rights reserved.

Bottled Water Basics

MedlinePlus

... the following measures: Use a point-of-use filter Consider using point-of-use (per- 2 Bottled ... tap sonal use, end-of-tap, under sink) filters that remove particles one micrometer or less in ...

Computer Simulations of Bottle Brushes: From Melts to Soft Networks

DOE PAGES

Cao, Zhen; Carrillo, Jan-Michael Y.; Sheiko, Sergei S.; ...

2015-07-13

We use a combination of Molecular dynamics simulations and analytical calculations, and study dens bottle-brush systems in a melt and network State. Analysis of our simulation results shows that bottle-brush macromolecules in melt behave as ideal chains with effective Kuhn length b K. Simulations show that the bottle-brush-induced bending rigidity is due to an entropy decrease caused by redistribution of the side chains upon backbone bending. The Kuhn length of the bottle:brushes increases with increasing the side-chain degree of polymerization n sc as b K proportional to n sc 0.46. Moreover, this model of bottle brush macromolecules is extended tomore » describe mechanical properties of bottle brush networks in linear and nonlinear deformation regimes. In the linear deformation regime, the network shear modulus scales with the degree of polymerization of the side chains as G 0 proportional to (n sc + 1) -1 as long as the ratio of the Kuhn length, b K, to the size of the fully extended bottle-brush backbone between cross-links, R-max, is smaller than unity, b K/R max << 1. Bottle-brush networks With b K/R max proportional to 1 demonstrate behavior similar to that of networks Of semiflexible chains with G 0 proportional to n sc -0.5. Finally, in the nonlinear network deformation regime, the deformation-dependent shear modulus is a universal function of the first strain invariant I 1 and bottle-brush backbone deformation ratio beta describing stretching ability of the bottle-brush backbone between cross-links.« less

Bottles to trees: Plastic beverage bottles as an alternative nursery growing container for reforestation in developing countries.

PubMed

Khurram, Safiullah; Burney, Owen T; Morrissey, Robert C; Jacobs, Douglass F

2017-01-01

Reforestation is needed globally to help restore degraded sites, combat desertification, protect watersheds, and provide forest products. This involves planting forest tree seedlings grown in local nurseries, but technologies to produce quality seedlings are lacking in developing countries. Modern nursery containers used to propagate seedlings have internal-surface barriers (ribs or ridges) or side-slits to prevent root spiraling. These are cost prohibitive or unavailable in developing countries and so polybags (plastic bags) are more commonly used, despite their tendency to produce seedlings with deformed root systems that have less potential to establish on field sites. Discarded plastic bottles, which are readily available worldwide, may be a feasible alternative for seedling propagation. We conducted two experiments to assess the potential of repurposed plastic beverage bottles to grow quality trees: 1) Container Comparison-to evaluate Arizona walnut (Juglans major [Toor.] Heller) and Afghan pine (Pinus eldarica Medw.) seedling root and shoot development in two plastic bottle types compared to modern nursery containers and polybags, and 2) Bottle Modification-to examine the effects of root spiraling prevention techniques (side-slits, internal-ridges, and control) and container opacity (green, black, and clear) on Afghan pine seedling morphological attributes. Nursery growth and first-year seedling field performance were evaluated for both experiments. In experiment one, seedlings of both species had fewer spiraled roots in bottle containers compared to polybags. Arizona walnut had more fibrous root systems in polybags, while Afghan pine root system fibrosity was greatest in bottle containers. First-year field performance of both species was not affected by container type. In experiment two, less spiraled roots occurred in containers with air-slits and interior-ridges compared to the control. The effects of container opacity on seedling morphology were

Bottles to trees: Plastic beverage bottles as an alternative nursery growing container for reforestation in developing countries

PubMed Central

Khurram, Safiullah; Burney, Owen T.; Morrissey, Robert C.

2017-01-01

Reforestation is needed globally to help restore degraded sites, combat desertification, protect watersheds, and provide forest products. This involves planting forest tree seedlings grown in local nurseries, but technologies to produce quality seedlings are lacking in developing countries. Modern nursery containers used to propagate seedlings have internal-surface barriers (ribs or ridges) or side-slits to prevent root spiraling. These are cost prohibitive or unavailable in developing countries and so polybags (plastic bags) are more commonly used, despite their tendency to produce seedlings with deformed root systems that have less potential to establish on field sites. Discarded plastic bottles, which are readily available worldwide, may be a feasible alternative for seedling propagation. We conducted two experiments to assess the potential of repurposed plastic beverage bottles to grow quality trees: 1) Container Comparison–to evaluate Arizona walnut (Juglans major [Toor.] Heller) and Afghan pine (Pinus eldarica Medw.) seedling root and shoot development in two plastic bottle types compared to modern nursery containers and polybags, and 2) Bottle Modification–to examine the effects of root spiraling prevention techniques (side-slits, internal-ridges, and control) and container opacity (green, black, and clear) on Afghan pine seedling morphological attributes. Nursery growth and first-year seedling field performance were evaluated for both experiments. In experiment one, seedlings of both species had fewer spiraled roots in bottle containers compared to polybags. Arizona walnut had more fibrous root systems in polybags, while Afghan pine root system fibrosity was greatest in bottle containers. First-year field performance of both species was not affected by container type. In experiment two, less spiraled roots occurred in containers with air-slits and interior-ridges compared to the control. The effects of container opacity on seedling morphology were

Mechanics of sucking: comparison between bottle feeding and breastfeeding

PubMed Central

2010-01-01

Background There is very little evidence of the similarity of the mechanics of maternal and bottle feeding. We assessed the mechanics of sucking in exclusive breastfeeding, exclusive bottle feeding, and mixed feeding. The hypothesis established was that physiological pattern for suckling movements differ depending on the type of feeding. According to this hypothesis, babies with breastfeeding have suckling movements at the breast that are different from the movements of suckling a teat of babies fed with bottle. Children with mixed feeding mix both types of suckling movements. Methods Cross-sectional study of infants aged 21-28 days with only maternal feeding or bottle feeding (234 mother-infant pairs), and a randomized open cross-over field trial in newborns aged 21-28 days and babies aged 3-5 months with mixed feeding (125 mother-infant pairs). Primary outcome measures were sucks and pauses. Results Infants aged 21-28 days exclusively bottle-fed showed fewer sucks and the same number of pauses but of longer duration compared to breastfeeding. In mixed feeding, bottle feeding compared to breastfeeding showed the same number of sucks but fewer and shorter pauses, both at 21-28 days and at 3-5 months. The mean number of breastfeedings in a day (in the mixed feed group) was 5.83 ± 1.93 at 21-28 days and 4.42 ± 1.67 at 3-5 months. In the equivalence analysis of the mixed feed group, the 95% confidence interval for bottle feeding/breastfeeding ratio laid outside the range of equivalence, indicating 5.9-8.7% fewer suction movements, and fewer pauses, and shorter duration of them in bottle feeding compared with breastfeeding. Conclusions The mechanics of sucking in mixed feeding lay outside the range of equivalence comparing bottle feeding with breastfeeding, although differences were small. Children with mixed feeding would mix both types of sucking movements (breastfeeding and bottle feeding) during the learning stage and adopt their own pattern. PMID:20149217

Shape transformation of viral capsids and HIV

NASA Astrophysics Data System (ADS)

Nguyen, Toan

2005-03-01

We present a continuum description of the shape transformation of viral capsids. The cone-like HIV virus is shown to be an thermodynamic stable shape, intermediate between icosahedral and sphero-cylinder capsid shapes. A generalized Caspar-Klug classification is introduced to describe spherical, conical and cylinderical shapes of virus.

EXAMINATION OF BOTTLED WATER FOR NONTUBERCULOUS MYCOBACTERIA

EPA Science Inventory

The objective of this study was to examine bottled water for the presence of nontuberculous mycobacteria as a potential source of infection in AIDS patients. Twenty brands of bottled water commonly used in the Los Angeles area were tested for the presence of nontuberculous mycoba...

Gas Property Demonstrations Using Plastic Water Bottles

ERIC Educational Resources Information Center

Campbell, Dean J.; Bannon, Stephen J.; Gunter, Molly M.

2011-01-01

Plastic water bottles are convenient containers for demonstrations of gas properties illustrating Boyle's law, Charles's law, and Avogadro's law. The contents of iron-based disposable hand warmer packets can be used to remove oxygen gas from the air within an unfilled plastic water bottle.

Beer bottle whistling: a stochastic Hopf bifurcation

NASA Astrophysics Data System (ADS)

Boujo, Edouard; Bourquard, Claire; Xiong, Yuan; Noiray, Nicolas

2017-11-01

Blowing in a bottle to produce sound is a popular and yet intriguing entertainment. We reproduce experimentally the common observation that the bottle ``whistles'', i.e. produces a distinct tone, for large enough blowing velocity and over a finite interval of blowing angle. For a given set of parameters, the whistling frequency stays constant over time while the acoustic pressure amplitude fluctuates. Transverse oscillations of the shear layer in the bottle's neck are clearly identified with time-resolved particle image velocimetry (PIV) and proper orthogonal decomposition (POD). To account for these observations, we develop an analytical model of linear acoustic oscillator (the air in the bottle) subject to nonlinear stochastic forcing (the turbulent jet impacting the bottle's neck). We derive a stochastic differential equation and, from the associated Fokker-Planck equation and the measured acoustic pressure signals, we identify the model's parameters with an adjoint optimization technique. Results are further validated experimentally, and allow us to explain (i) the occurrence of whistling in terms of linear instability, and (ii) the amplitude of the limit cycle as a competition between linear growth rate, noise intensity, and nonlinear saturation. E. B. and N. N. acknowledge support by Repower and the ETH Zurich Foundation.

POWASSAN VIRUS: MORPHOLOGY AND CYTOPATHOLOGY.

PubMed

ABDELWAHAB, K S; ALMEIDA, J D; DOANE, F W; MCLEAN, D M

1964-05-02

Powassan virus, a North American tickborne group B arbovirus, multiplied after simultaneous inoculation into bottles or tubes of virus and trypsinized suspension of continuous-line cultures of rhesus monkey kidney cells, strain LLC-MK2. Cytopathic effects comprising cell rounding and cytoplasmic vacuolation were first observed five days after inoculation. Mixture of Powassan antiserum with virus before inoculation into tissue cultures inhibited the appearance of cytopathic effects. Hemagglutinins for rooster erythrocytes, optimally at pH 6.4 and 22 degrees C., first appeared in tissue culture supernatant fluids four days after inoculation.Electron microscopic observation of thin sections of infected tissue culture cells showed virus particles 360-380 A.U. along outer cell membranes and edges of cytoplasmic vacuoles. In phosphotungstic acid negatively stained preparations, intact virus particles, 400-450 A.U. total diameter, were observed inside infected cells. In particles in which the peripheral layer became discontinuous, geometrically arranged subunits compatible with cubic symmetry were observed.

Measuring the significance of pearlescence in real-time bottle forming

NASA Astrophysics Data System (ADS)

Nixon, J.; Menary, G.; Yan, S.

2018-05-01

This work examines the optical properties of polyethylene terephthalate (PET) bottles during the stretch-blow-moulding (SBM) process. PET has a relatively large process window with regards to process parameters, however if the boundaries are pushed, the resultant bottle can become insufficient for consumer requirements. One aspect of this process is the onset of pearlescence in the bottle material, where the bottle becomes opaque due to elevated stress whitening. Experimental trials were carried out using a modified free-stretch-blow machine where the deforming bottle was examined in free air. The strain values of the deformation were measured using digital image correlation (DIC) and the optical properties were measured relative to the initial amorphous PET preform. The results reveal that process parameters can significantly affect pearlescence. The detrimental level of pearlescence may be predicted therefore reducing the probability of poorly formed bottles.

Acoustic Emission Test for Aircraft Halon 1301 Fire Extinguisher Bottles

DOT National Transportation Integrated Search

1998-04-01

An acoustic emission test for aircraft Halon 1301 bottles has been developed, a prototype acoustic emission test system constructed, and over 200 used bottles tested at the repair facilities of the two manufacturers of these bottles. The system monit...

ARRAYS OF BOTTLES OF PLUTONIUM NITRATE SOLUTION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Margaret A. Marshall

2012-09-01

In October and November of 1981 thirteen approaches-to-critical were performed on a remote split table machine (RSTM) in the Critical Mass Laboratory of Pacific Northwest Laboratory (PNL) in Richland, Washington using planar arrays of polyethylene bottles filled with plutonium (Pu) nitrate solution. Arrays of up to sixteen bottles were used to measure the critical number of bottles and critical array spacing with a tight fitting Plexiglas® reflector on all sides of the arrays except the top. Some experiments used Plexiglas shells fitted around each bottles to determine the effect of moderation on criticality. Each bottle contained approximately 2.4 L ofmore » Pu(NO3)4 solution with a Pu content of 105 g Pu/L and a free acid molarity H+ of 5.1. The plutonium was of low 240Pu (2.9 wt.%) content. These experiments were sponsored by Rockwell Hanford Operations because of the lack of experimental data on the criticality of arrays of bottles of Pu solution such as might be found in storage and handling at the Purex Facility at Hanford. The results of these experiments were used “to provide benchmark data to validate calculational codes used in criticality safety assessments of [the] plant configurations” (Ref. 1). Data for this evaluation were collected from the published report (Ref. 1), the approach to critical logbook, the experimenter’s logbook, and communication with the primary experimenter, B. Michael Durst. Of the 13 experiments preformed 10 were evaluated. One of the experiments was not evaluated because it had been thrown out by the experimenter, one was not evaluated because it was a repeat of another experiment and the third was not evaluated because it reported the critical number of bottles as being greater than 25. Seven of the thirteen evaluated experiments were determined to be acceptable benchmark experiments. A similar experiment using uranyl nitrate was benchmarked as U233-SOL-THERM-014.« less

27 CFR 19.599 - Bottling and packaging records.

Code of Federal Regulations, 2013 CFR

2013-04-01

... spirits bottled or packaged (if different from the proof recorded under paragraph (f) of this section); (k) Total quantity bottled, packaged, or otherwise disposed of in bulk; (l) Losses or gains of the distilled...

27 CFR 19.599 - Bottling and packaging records.

Code of Federal Regulations, 2012 CFR

2012-04-01

... spirits bottled or packaged (if different from the proof recorded under paragraph (f) of this section); (k) Total quantity bottled, packaged, or otherwise disposed of in bulk; (l) Losses or gains of the distilled...

27 CFR 19.599 - Bottling and packaging records.

Code of Federal Regulations, 2014 CFR

2014-04-01

... spirits bottled or packaged (if different from the proof recorded under paragraph (f) of this section); (k) Total quantity bottled, packaged, or otherwise disposed of in bulk; (l) Losses or gains of the distilled...

27 CFR 26.314 - Distinctive liquor bottles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Distinctive liquor bottles. 26.314 Section 26.314 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU..., including a photograph of the distinctive liquor bottle, to Customs officials at each affected port of entry...

27 CFR 26.314 - Distinctive liquor bottles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Distinctive liquor bottles. 26.314 Section 26.314 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU..., including a photograph of the distinctive liquor bottle, to Customs officials at each affected port of entry...

27 CFR 19.599 - Bottling and packaging records.

Code of Federal Regulations, 2011 CFR

2011-04-01

... proof recorded under paragraph (f) of this section); (k) Total quantity bottled, packaged, or otherwise disposed of in bulk; (l) Losses or gains of the distilled spirits product; and (m) If labeled as bottled in...

From Comb-like Polymers to Bottle-Brushes

NASA Astrophysics Data System (ADS)

Liang, Heyi; Cao, Zhen; Dobrynin, Andrey; Sheiko, Sergei

We use a combination of the coarse-grained molecular dynamics simulations and scaling analysis to study conformations of bottle-brushes and comb-like polymers in a melt. Our analysis show that bottle-brushes and comb-like polymers can be in four different conformation regimes depending on the number of monomers between grafted side chains and side chain degree of polymerization. In loosely-grafted comb regime (LC) the degree of polymerization between side chains is longer than side chain degree of polymerization, such that the side chains belonging to the same macromolecule do not overlap. Crossover to a new densely-grafted comb regime (DC) takes place when side chains begin to overlap reducing interpenetration of side chains belonging to different macromolecules. In these two regimes both side-chains and backbone behave as unperturbed linear chains with the effective Kuhn length of the backbone being close to that of linear chain. Further decrease spacer degree of polymerization results in crossover to loosely-grafted bottle-brush regime (LB). In this regime, the bottle-brush backbone is stretched while the side-chains still maintain ideal chain conformation. Finally, for even shorter spacer between grafted side chains, which corresponds to densely-grafted bottle-brush regime (DB), the backbone adopts a fully extended chain conformation, and side-chains begin to stretch to maintain a constant monomer density. NSF DMR-1409710, DMR-1407645, DMR-1624569, DMR-1436201.

Teaching light scattering spectroscopy: the dimension and shape of tobacco mosaic virus.

PubMed Central

Santos, N C; Castanho, M A

1996-01-01

The tobacco mosaic virus is used as a model molecular assembly to illustrate the basic potentialities of light scattering techniques (both static and dynamic) to undergraduates. The work has two objectives: a pedagogic one (introducing light scattering to undergraduate students) and a scientific one (stabilization of the virus molecular assembly structure by the nucleic acid). Students are first challenged to confirm the stabilization of the cylindrical shape of the virus by the nucleic acid, at pH and ionic strength conditions where the coat proteins alone do not self-assemble. The experimental intramolecular scattering factor is compared with the theoretical ones for several model geometries. The data clearly suggest that the geometry is, in fact, a rod. Comparing the experimental values of gyration radius and hydrodynamic radius with the theoretical expectations further confirms this conclusion. Moreover, the rod structure is maintained over a wider range of pH and ionic strength than that valid for the coat proteins alone. The experimental values of the diffusion coefficient and radius of gyration are compared with the theoretical expectations assuming the dimensions detected by electron microscopy techniques. In fact, both values are in agreement (length approximately 300 nm, radius approximately 20 nm). PMID:8874039

Detection of bottled liquid explosives by near infrared

NASA Astrophysics Data System (ADS)

Itozaki, Hide; Miyamura, Ryu; Sato-Akaba, Hideo

2012-10-01

Bottled liquids are limited to be brought in the airplane, because liquid explosives have been used in some terrorist attaches recently. A bottled liquid scanner is expected to be developed. Liquid scanner using near infrared technologies is being developed by us. Many spectrum of liquids have been collected and analyzed by chemometorics in order to separate safe beverage to explosive and dangerous liquids. This bottled liquid scanner had feasibility tests in some international airport in Japan and obtained good review from security people in the airport.

27 CFR 19.402 - Inventories of bottled and packaged spirits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Than Denaturation and Manufacture of Articles Inventories § 19.402 Inventories of bottled and packaged spirits. (a) Physical inventories. (1) Physical inventories of bottled and packaged spirits in the... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Inventories of bottled and...

Life cycle assessment of bottled water: A case study of Green2O products.

PubMed

Horowitz, Naomi; Frago, Jessica; Mu, Dongyan

2018-06-01

This study conducted a full life cycle analysis of bottled water on four types of bottles: ENSO, PLA (corn based), recycled PET, and regular (petroleum based) PET, to discern which bottle material is more beneficial to use in terms of environmental impacts. PET bottles are the conventional bottles used that are not biodegradable and accumulate in landfills. PLA corn based bottles are derived from an organic substance and are degradable under certain environmental conditions. Recycled PET bottles are purified PET bottles that were disposed of and are used in a closed loop system. An ENSO bottle contains a special additive which is designed to help the plastic bottle degrade after disposed of in a landfill. The results showed that of all fourteen impact categories examined, the recycled PET and ENSO bottles were generally better than the PLA and regular PET bottles; however, the ENSO had the highest impacts in the categories of global warming and respiratory organics, and the recycled PET had the highest impact in the eutrophication category. The life cycle stages that were found to have the highest environmental impacts were the bottle manufacturing stage and the bottled water distribution to storage stage. Analysis of the mixed bottle material based on recycled PET resin and regular PET resin was discussed as well, in which key impact categories were identified. The PLA bottle contained extremely low impacts in the carcinogens, respiratory organics and global warming categories, yet it still contained the highest impacts in seven of the fourteen categories. Overall, the results demonstrate that the usage of more sustainable bottles, such as biodegradable ENSO bottles and recycled PET bottles, appears to be a viable option for decreasing impacts of the bottled water industry on the environment. Published by Elsevier Ltd.

Calcite precipitates in Slovenian bottled waters.

PubMed

Stanič, Tamara Ferjan; Miler, Miloš; Brenčič, Mihael; Gosar, Mateja

2017-06-01

Storage of bottled waters in varying ambient conditions affects its characteristics. Different storage conditions cause changes in the initial chemical composition of bottled water which lead to the occurrence of precipitates with various morphologies. In order to assess the relationship between water composition, storage conditions and precipitate morphology, a study of four brands of Slovenian bottled water stored in PET bottles was carried out. Chemical analyses of the main ions and measurements of the physical properties of water samples were performed before and after storage of water samples at different ambient conditions. SEM/EDS analysis of precipitates was performed after elapsed storage time. The results show that the presence of Mg 2+ , SO 4 2- , SiO 2 , Al, Mn and other impurities such as K + , Na + , Ba and Sr in the water controlled precipitate morphology by inhibiting crystal growth and leading to elongated rhombohedral calcite crystal forms which exhibit furrowed surfaces and calcite rosettes. Different storage conditions, however, affected the number of crystallization nuclei and size of calcite crystals. Hollow calcite spheres composed of cleavage rhombohedrons formed in the water with variable storage conditions by a combination of evaporation and precipitation of water droplets during high temperatures or by the bubble templating method.

Risk perceptions of arsenic in tap water and consumption of bottled water

NASA Astrophysics Data System (ADS)

Jakus, Paul M.; Shaw, W. Douglass; Nguyen, To N.; Walker, Mark

2009-05-01

The demand for bottled water has increased rapidly over the past decade, but bottled water is extremely costly compared to tap water. The convenience of bottled water surely matters to consumers, but are others factors at work? This manuscript examines whether purchases of bottled water are associated with the perceived risk of tap water. All of the past studies on bottled water consumption have used simple scale measures of perceived risk that do not correspond to risk measures used by risk analysts. We elicit a probability-based measure of risk and find that as perceived risks rise, expenditures for bottled water rise.

Determinants of using pacifier and bottle feeding

PubMed Central

Buccini, Gabriela dos Santos; Benício, Maria Helena D’Aquino; Venancio, Sonia Isoyama

2014-01-01

OBJECTIVE To analyze the factors associated with the use of pacifiers and/or bottle feeding in infants aged under one year. METHODS This is a cross-sectional study with 34,366 children and using data from the database of the 2nd Nationwide Survey of Breastfeeding Prevalence performed in the Brazilian capitals and Federal District in 2008. Cluster sampling was used. The questionnaire included questions about the use of artificial nipples in the last 24 hours. The analysis considered three outcomes: exclusive use of pacifier, exclusive use of bottle feeding, and use of artificial nipples (pacifier and bottle feeding). Prevalence ratios were obtained using Poisson regression with robust variance following a hierarchical model. RESULTS The following factors were associated with exclusive use of the pacifier: mother working outside the home, primiparity, child was not breastfed within the first hour, and child had consumed tea on the first day at home. The following factors were associated with exclusive use of bottle feeding: mother working outside the home, primiparity, low birth weight, child not breastfed within the first hour, and child had consumed milk formula and tea on the first day at home. The following factors were associated with use of artificial nipples (pacifier and bottle feeding): mother working outside the home, primiparity, cesarean delivery, the male gender, low birth weight, born in a hospital not accredited as “baby friendly”, required health baby monitoring in the Primary Health Care Unit (PR = 0.91), and child had consumed milk formula, water, or tea on the first day at home. CONCLUSIONS This study identified profiles of exclusive users of pacifiers, bottle feeding, and both. The provided information can guide preventive practices for child health. PMID:25210816

How dirty are your reusable water bottles?

NASA Astrophysics Data System (ADS)

Williams, S.

2017-12-01

Reusable water bottles are an environment-friendly option but may grow harmful bacteria if not washed regularly. To test whether washing habits affect bacterial growth, I swabbed 10 different plastic reusable bottles and counted colony growth after laboratory incubation. My results did not show a clear relationship between days since last wash and colony growth.

Wine bottle colour and oxidative spoilage: whole bottle light exposure experiments under controlled and uncontrolled temperature conditions.

PubMed

Dias, Daniel A; Clark, Andrew C; Smith, Trevor A; Ghiggino, Kenneth P; Scollary, Geoffrey R

2013-06-15

Exposure of a Chardonnay wine to light from a mercury vapour lamp under controlled temperature conditions showed that colour enhancement was dependent on bottle colour. The increase in colouration was Antique Greenbottle type. Xanthylium pigments were identified as one component contributing to the observed enhancement of colour. The presence of oxygen was shown to be a critical factor to initiate the formation of these xanthylium pigments during light exposure. Without temperature control, wine colour development was highest in Antique Green and lowest in Flint. This alternate order reflects the ability of the darker bottles to retain heat longer than lighter coloured ones as confirmed by surface temperature decay rates. Specific pigments contributing to the wine colour enhancement in uncontrolled temperature/light exposure experiments could not be identified, although tentative evidence was obtained for the presence of flavan-3-ol based compounds. The different bottle glass surfaces did not influence the rate of loss of dissolved oxygen or oxidation of ascorbic acid. The potential to develop the results obtained in this study to identify markers for light and/or temperature exposure of white wines is discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

27 CFR 25.157 - Determination of tax on bottled beer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... bottled beer. 25.157 Section 25.157 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.157 Determination of tax on bottled beer. The quantities of bottled beer removed subject to tax shall be computed to...

27 CFR 25.157 - Determination of tax on bottled beer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... bottled beer. 25.157 Section 25.157 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.157 Determination of tax on bottled beer. The quantities of bottled beer removed subject to tax shall be computed to...

27 CFR 25.157 - Determination of tax on bottled beer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... bottled beer. 25.157 Section 25.157 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.157 Determination of tax on bottled beer. The quantities of bottled beer removed subject to tax shall be computed to...

27 CFR 25.157 - Determination of tax on bottled beer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... bottled beer. 25.157 Section 25.157 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.157 Determination of tax on bottled beer. The quantities of bottled beer removed subject to tax shall be computed to...

27 CFR 25.157 - Determination of tax on bottled beer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... bottled beer. 25.157 Section 25.157 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.157 Determination of tax on bottled beer. The quantities of bottled beer removed subject to tax shall be computed to...

Scanning electron microscopic study of a Ciloxan bottle blocked by ciprofloxacin crystals.

PubMed

John, T

2001-12-01

To report blockage of a commercially available ciprofloxacin bottle by white crystalline deposits. This study evaluated the ultrastructural features of the ciprofloxacin crystals. A patient underwent intensive topical treatment of an infectious corneal ulcer with commercially available ciprofloxacin 0.3% ophthalmic solution. During treatment, the patient was unable to obtain medication from the ciprofloxacin bottle and required a new prescription. Examination of the bottle revealed that about 50% of the medication remained, but compression of the bottle with any amount of force failed to deliver any medication. On closer examination, a white material partially filled the nozzle track of the bottle and was on the outer bottle near the nozzle and the inner surface of the bottle cap. These white crystalline deposits were evaluated by scanning electron microscopy. Plate-like, needle, cable and spaghetti-like crystals were found. The needle crystals formed multiple petaloid patterns. This is the first report of blockage of a commercially available ciprofloxacin 0.3% bottle by ciprofloxacin crystals and the inability to deliver medication from the bottle. Ultrastructural study of the white crystalline deposits revealed four types of ciprofloxacin crystals.

Polycarbonate Bottle Use and Urinary Bisphenol A Concentrations

PubMed Central

Carwile, Jenny L.; Luu, Henry T.; Bassett, Laura S.; Driscoll, Daniel A.; Yuan, Caterina; Chang, Jennifer Y.; Ye, Xiaoyun; Calafat, Antonia M.; Michels, Karin B.

2009-01-01

Background Bisphenol A (BPA) is a high-production-volume chemical commonly used in the manufacture of polycarbonate plastic. Low-level concentrations of BPA in animals and possibly in humans may cause endocrine disruption. Whether ingestion of food or beverages from polycarbonate containers increases BPA concentrations in humans has not been studied. Objectives We examined the association between use of polycarbonate beverage containers and urinary BPA concentrations in humans. Methods We conducted a nonrandomized intervention of 77 Harvard College students to compare urinary BPA concentrations collected after a washout phase of 1 week to those taken after an intervention week during which most cold beverages were consumed from polycarbonate drinking bottles. Paired t-tests were used to assess the difference in urinary BPA concentrations before and after polycarbonate bottle use. Results The geometric mean urinary BPA concentration at the end of the washout phase was 1.2 μg/g creatinine, increasing to 2.0 μg/g creatinine after 1 week of polycarbonate bottle use. Urinary BPA concentrations increased by 69% after use of polycarbonate bottles (p < 0.0001). The association was stronger among participants who reported ≥ 90% compliance (77% increase; p < 0.0001) than among those reporting < 90% compliance (55% increase; p = 0.03), but this difference was not statistically significant (p = 0.54). Conclusions One week of polycarbonate bottle use increased urinary BPA concentrations by two-thirds. Regular consumption of cold beverages from polycarbonate bottles is associated with a substantial increase in urinary BPA concentrations irrespective of exposure to BPA from other sources. PMID:19750099

49 CFR 192.175 - Pipe-type and bottle-type holders.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Pipe-type and bottle-type holders. 192.175 Section....175 Pipe-type and bottle-type holders. (a) Each pipe-type and bottle-type holder must be designed so... equipment, that might cause corrosion or interfere with the safe operation of the holder. (b) Each pipe-type...

49 CFR 192.175 - Pipe-type and bottle-type holders.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Pipe-type and bottle-type holders. 192.175 Section....175 Pipe-type and bottle-type holders. (a) Each pipe-type and bottle-type holder must be designed so... equipment, that might cause corrosion or interfere with the safe operation of the holder. (b) Each pipe-type...

What about the Bottle? Answers to Common Questions.

ERIC Educational Resources Information Center

Laird, Valerie

2001-01-01

Acknowledges the large amount of confusing information about bottle feeding in areas including nutrition, sanitation, dental health, psychology, and child development. Answers specific questions pertaining to choice of formula and formula preparation, supporting breastfeeding, bottle choice, solid food introduction, feeding position, spitting up,…

An axisymmetric PFEM formulation for bottle forming simulation

NASA Astrophysics Data System (ADS)

Ryzhakov, Pavel B.

2017-01-01

A numerical model for bottle forming simulation is proposed. It is based upon the Particle Finite Element Method (PFEM) and is developed for the simulation of bottles characterized by rotational symmetry. The PFEM strategy is adapted to suit the problem of interest. Axisymmetric version of the formulation is developed and a modified contact algorithm is applied. This results in a method characterized by excellent computational efficiency and volume conservation characteristics. The model is validated. An example modelling the final blow process is solved. Bottle wall thickness is estimated and the mass conservation of the method is analysed.

On sampling biases arising from insufficient bottle flushing

NASA Astrophysics Data System (ADS)

Codispoti, L. A.; Paver, C. R.

2016-02-01

Collection of representative water samples using carousel bottles is important for accurately determining biological and chemical gradients. The development of more technologically advanced instrumentation and sampling apparatus causes sampling packages to increase and "soak times" to decrease, increasing the probability that insufficient bottle flushing will produce biased results. Qualitative evidence from various expeditions suggest that insufficient flushing may be a problem. Here we report on multiple field experiments that were conducted to better quantify the errors that can arise from insufficient bottle flushing. Our experiments suggest that soak times of more than 2 minutes are sometimes required to collect a representative sample.

Physicochemical properties of some bottled water brands in Alexandria Governorate, Egypt.

PubMed

Ibrahim, Hesham Z; Mohammed, Heba A G; Hafez, Afaf M

2014-08-01

Many people use bottled water instead of tap water for many reasons such as taste, ease of carrying, and thinking that it is safer than tap water. Irrespective of the reason, bottled water consumption has been steadily growing in the world for the past 30 years. In Egypt, this is still increasing to reach 3.8 l/person/day, despite its high price compared with tap water. The purpose of this study was to evaluate the physicochemical quality of some bottled water brands and to compare the quality with that reported on manufacture's labeling, Egyptian, and International standards. Fourteen bottled water brands were selected from the local markets of Alexandria city. Three bottles from each brand were randomly sampled, making a total sample size of 42 bottles. Sampling occurred between July 2012 and September 2012. Each bottle was analyzed for its physicochemical parameter and the average was calculated for each brand. The results obtained were compared with the Egyptian standard for bottled water, Food and Drug Administration (FDA), and with bottled water labels. In all bottles in the study, pH values ranged between 7.21 and 8.23, conductivity ranged between 195 and 675 μs/cm, and total dissolved solids, sulfate, chloride, and fluoride were within the range specified by the FDA. Calcium concentrations ranged between 2.7373 and 29.2183 mg/l, magnesium concentrations ranged between 5.7886 and 17.6633 mg/l, sodium between 14.5 and 205.8 mg/l, and potassium between 6.5 and 29.8 mg/l. For heavy metals such as iron, zinc, copper, and manganese, all of them were in conformity with the Egyptian standards and FDA, but nickel concentration in 11 brands was higher than the Egyptian standards. Twelve brands were higher than the Egyptian standards in cadmium concentration, but on comparison with FDA there were only five brands exceeding limits. Lead concentrations were out of range for all brands. On comparison with the labeled values, the quality of bottled water was not

Infant feeding bottle design, growth and behaviour: results from a randomised trial

PubMed Central

2012-01-01

Background Whether the design of an anti-vacuum infant feeding bottle influences infant milk intake, growth or behavior is unknown, and was the subject of this randomized trial. Methods Subjects 63 (36 male) healthy, exclusively formula-fed term infants. Intervention Randomisation to use Bottle A (n = 31), one-way air valve: Philips Avent) versus Bottle B (n = 32), internal venting system: Dr Browns). 74 breast-fed reference infants were recruited, with randomisation (n = 24) to bottle A (n = 11) or B (n = 13) if bottle-feeding was subsequently introduced. Randomisation stratified by gender and parity; computer-based telephone randomisation by independent clinical trials unit. Setting Infant home. Primary outcome measure infant weight gain to 4 weeks. Secondary outcomes (i) milk intake (ii) infant behaviour measured at 2 weeks (validated 3-day diary); (iii) risk of infection; (iv) continuation of breastfeeding following introduction of mixed feeding. Results Number analysed for primary outcome Bottle A n = 29, Bottle B n = 25. Primary outcome There was no significant difference in weight gain between randomised groups (0-4 weeks Bottle A 0.74 (SD 1.2) SDS versus bottle B 0.51 (0.39), mean difference 0.23 (95% CI -0.31 to 0.77). Secondary outcomes Infants using bottle A had significantly less reported fussing (mean 46 versus 74 minutes/day, p < 0.05) than those using bottle B. There was no significant difference in any other outcome measure. Breast-fed reference group There were no significant differences in primary or secondary outcomes between breast-fed and formula fed infants. The likelyhood of breastfeeding at 3 months was not significantly different in infants subsequently randomised to bottle A or B. Conclusion Bottle design may have short-term effects on infant behaviour which merit further investigation. No significant effects were seen on milk intake or growth; confidence in these findings is limited by the small sample size and this needs confirmation in

Powassan Virus: Morphology and Cytopathology

PubMed Central

Abdelwahab, K. S. E.; Almeida, J. D.; Doane, F. W.; McLean, D. M.

1964-01-01

Powassan virus, a North American tickborne group B arbovirus, multiplied after simultaneous inoculation into bottles or tubes of virus and trypsinized suspension of continuous-line cultures of rhesus monkey kidney cells, strain LLC-MK2. Cytopathic effects comprising cell rounding and cytoplasmic vacuolation were first observed five days after inoculation. Mixture of Powassan antiserum with virus before inoculation into tissue cultures inhibited the appearance of cytopathic effects. Hemagglutinins for rooster erythrocytes, optimally at pH 6.4 and 22° C., first appeared in tissue culture supernatant fluids four days after inoculation. Electron microscopic observation of thin sections of infected tissue culture cells showed virus particles 360-380 A.U. along outer cell membranes and edges of cytoplasmic vacuoles. In phosphotungstic acid negatively stained preparations, intact virus particles, 400-450 A.U. total diameter, were observed inside infected cells. In particles in which the peripheral layer became discontinuous, geometrically arranged subunits compatible with cubic symmetry were observed. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 5 PMID:14146854

Impact of oxygen dissolved at bottling and transmitted through closures on the composition and sensory properties of a Sauvignon Blanc wine during bottle storage.

PubMed

Lopes, Paulo; Silva, Maria A; Pons, Alexandre; Tominaga, Takatoshi; Lavigne, Valérie; Saucier, Cédric; Darriet, Philippe; Teissedre, Pierre-Louis; Dubourdieu, Denis

2009-11-11

This work outlines the results from an investigation to determine the effect of the oxygen dissolved at bottling and the specific oxygen barrier properties of commercially available closures on the composition, color and sensory properties of a Bordeaux Sauvignon Blanc wine during two years of storage. The importance of oxygen for wine development after bottling was also assessed using an airtight bottle ampule. Wines were assessed for the antioxidants (SO(2) and ascorbic acid), varietal thiols (4-mercapto-4-methylpentan-2-one, 3-mercaptohexan-1-ol), hydrogen sulfide and sotolon content, and color throughout 24 months of storage. In addition, the aroma and palate properties of wines were also assessed. The combination of oxygen dissolved at bottling and the oxygen transferred through closures has a significant effect on Sauvignon Blanc development after bottling. Wines highly exposed to oxygen at bottling and those sealed with a synthetic, Nomacorc classic closure, highly permeable to oxygen, were relatively oxidized in aroma, brown in color, and low in antioxidants and volatile compounds compared to wines sealed with other closures. Conversely, wines sealed under more airtight conditions, bottle ampule and screw cap Saran-tin, have the slowest rate of browning, and displayed the greatest contents of antioxidants and varietal thiols, but also high levels of H(2)S, which were responsible for the reduced dominating character found in these wines, while wines sealed with cork stoppers and screw cap Saranex presented negligible reduced and oxidized characters.

Klein bottle logophysics: a unified principle for non-linear systems, cosmology, geophysics, biology, biomechanics and perception

NASA Astrophysics Data System (ADS)

Lucio Rapoport, Diego

2013-04-01

We present a unified principle for science that surmounts dualism, in terms of torsion fields and the non-orientable surfaces, notably the Klein Bottle and its logic, the Möbius strip and the projective plane. We apply it to the complex numbers and cosmology, to non-linear systems integrating the issue of hyperbolic divergences with the change of orientability, to the biomechanics of vision and the mammal heart, to the morphogenesis of crustal shapes on Earth in connection to the wavefronts of gravitation, elasticity and electromagnetism, to pattern recognition of artificial images and visual recognition, to neurology and the topographic maps of the sensorium, to perception, in particular of music. We develop it in terms of the fundamental 2:1 resonance inherent to the Möbius strip and the Klein Bottle, the minimal surfaces representation of the wavefronts, and the non-dual Klein Bottle logic inherent to pattern recognition, to the harmonic functions and vector fields that lay at the basis of geophysics and physics at large. We discuss the relation between the topographic maps of the sensorium, and the issue of turning inside-out of the visual world as a general principle for cognition, topological chemistry, cell biology and biological morphogenesis in particular in embryology

Water Jets from Bottles, Buckets, Barrels, and Vases with Holes

NASA Astrophysics Data System (ADS)

Lopac, Vjera

2015-03-01

Observation of the water jets flowing from three equidistant holes on the side of a vertical cylindrical bottle is an interesting and widely used didactical experiment illustrating the laws of fluids in motion. In this paper we analyze theoretically and numerically the ranges of the stationary water jets flowing from various rotationally symmetric vessels with holes, and their dependence on the height of the holes above the bottom, on thickness of the block supporting the vessel, and on different shapes of the vessel profile. This investigation was motivated by controversial descriptions and illustrations repeatedly found in physics textbooks and by the fact that previously in the physics teaching literature only the cylindrical vessel was treated.

Breast-feeding, bottle-feeding and Dr. Spock: the shifting context of choice.

PubMed

Knaak, Stephanie

2005-05-01

In today's environment, breast-feeding represents both a medical gold standard for infant feeding and a moral gold standard for mothering. The morally charged character of this discourse makes the notion of choice in infant feeding particularly problematic and fraught with difficulty. From an historical content analysis of selected editions from 1946 to 1998 of Dr. Spock's famous child-care manual, this paper explicates the process through which the breast versus bottle discourse has shifted over the last half-century, and how these shifts have shaped the context of choice within which mothers must make their infant-feeding decisions.

Fluoride Content of Bottled Drinking Waters in Qatar.

PubMed

Almulla, Hessa Ibrahim; King, Nigel M; Alnsour, Hamza Mohammad; Sajnani, Anand K

2016-12-01

Fluoridation of drinking water has been recognized as one of the most effective ways of achieving community-wide exposure to the caries prevention effects of fluoride (F). A vast majority of people in Qatar use bottled water for drinking. Use of bottled water without knowing the F level may expose children to dental caries risk if the F level is lower than optimal or to dental fluorosis if the F level is too high. The aim of this study was to determine the F concentration of bottled water available in Qatar. A total of 32 brands of bottled water were evaluated. The F concentrations displayed on the labels were recorded. The F ion-selective electrode method was used to measure the F concentration in water samples, and three measurements were taken for every sample to ensure reproducibility. The p value was set at 0.05. The F concentration ranged from 0.06 to 3.0 ppm with a mean value of 0.8 ppm (±0.88). The F levels were provided by the manufacturers on the labels of 60 % of the samples, but this was significantly lower than the measured F levels (p < 0.0001). Moreover, bottled water that was produced in Saudi Arabia had significantly higher levels of F when compared to those produced in other countries (p < 0.05). There was a wide variation in the F levels in the different brands of bottled water. Furthermore, there was a significant disparity between the F levels which were measured and those that were provided on the labels.

Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems

PubMed Central

Ardeshir, Amir; Narayan, Nicole R.; Méndez-Lagares, Gema; Lu, Ding; Rauch, Marcus; Huang, Yong; Van Rompay, Koen K. A.; Lynch, Susan V.; Hartigan-O'Connor, Dennis J.

2015-01-01

Diet has a strong influence on the intestinal microbiota in both humans and animal models. It is well established that microbial colonization is required for normal development of the immune system and that specific microbial constituents prompt the differentiation or expansion of certain immune cell subsets. Nonetheless, it has been unclear how profoundly diet might shape the primate immune system or how durable the influence might be. We show that breast-fed and bottle-fed infant rhesus macaques develop markedly different immune systems, which remain different 6 months after weaning when the animals begin receiving identical diets. In particular, breast-fed infants develop robust populations of memory T cells as well as T helper 17 (TH17) cells within the memory pool, whereas bottle-fed infants do not. These findings may partly explain the variation in human susceptibility to conditions with an immune basis, as well as the variable protection against certain infectious diseases. PMID:25186175

The switch to refillable bottled water in Indonesia: a serious health risk.

PubMed

Komarulzaman, Ahmad; de Jong, Eelke; Smits, Jeroen

2017-10-01

In recent years, the consumption of refillable bottled water has increased considerably in emerging countries. However, the quality of this water is often questionable, as authorities lack the capacity to properly check refilling depots. Given that refillable bottled water not only replaces unimproved water sources, but also better-quality sources, like piped and branded bottled water, its increasing use poses a major health risk. We investigate the motives behind the decision to switch to refillable bottled water in Indonesia. Findings indicate that this switch is driven by lifestyle motives, as well as by cost and availability considerations. It is mostly the young affluent households who switch from piped and 'other' sources to refillable bottled water. In rural areas, the tendency to make this switch is negatively affected by availability problems and the higher price of refillable bottled water. Availability and cost also influence the switch from branded bottled to refillable bottled water, but here it is the poorer households who have a higher propensity to switch. Further exploration of the lifestyle motive and affordability issues, as well as better monitoring of the refilling depots, are needed to improve the quality of drinking water in Indonesia and other emerging countries.

Detection of bottled explosives by near infrared

NASA Astrophysics Data System (ADS)

Itozaki, Hideo; Sato-Akaba, Hideo

2013-10-01

Bottled liquids are not allowed through the security gate in the airport, because liquid explosives have been used by the terrorists. However, passengers have a lot of trouble if they cannot bring their own bottles. For example, a mother would like to carry her own milk in the airplane for her baby. Therefore the detection technology of liquid explosives should be developed as soon as possible. This paper shows that near infrared spectroscopy can detect bottled explosives quickly. The transmission method cannot deal with milk in the sense of liquid inspection. Here we examined the reflection method to the test of milk. The inspection method with light cannot make test for the metal can. We also use ultrasonic method to check metal can simultaneously in order to expand test targets.

Evolutionary medicine: bottle feeding, birth spacing, and autism.

PubMed

Gallup, Gordon G; Hobbs, Dawn R

2011-09-01

To compensate for the high metabolic costs of lactation, the likelihood of re-impregnation shortly after childbirth is normally reduced due to hormonal changes triggered by breast feeding during the postpartum period. Nowadays, however, bottle feeding as a substitute for breast feeding precludes such changes and leads to early postpartum reinstatement of fertility. We suggest that recent data showing the risk of autism goes up dramatically as the time between pregnancies goes down [1] may be a byproduct of bottle feeding. The decision to bottle feed your last child may unwittingly put your next child at risk of being autistic. Copyright © 2011 Elsevier Ltd. All rights reserved.

Flutist produces four resonances with a single bottle

NASA Astrophysics Data System (ADS)

Ruiz, Michael J.; Boysen, Erika

2017-03-01

In a dramatic physics demonstration, a professional flutist produces four resonances with a 12 ounce Boylan soda bottle solely through her breath control. The 22 cm bottle acts like a Helmholtz resonator for the lowest pitch. The three higher pitches fall near the 3rd, 5th, and 7th harmonics for a 22 cm closed pipe. A video of this remarkable feat is provided (Ruiz 2016 YouTube: Four Resonances with a 12-ounce Soda Bottle (https://youtu.be/ibtVrp2NF_k)). The video also reveals that a flutist can bend resonance pitches by as much as 10% through control of air speed.

Bottle Characteristics of Topical International Glaucoma Medications versus Local Brands in Saudi Arabia

PubMed Central

Al-Jumaian, Nasser; Malik, Rizwan; Khandekar, Rajiv; Al-Humaidan, Abdullah; Al-Madany, Rana; Al-Qahtani, Reham; Altowairqi, Ahmed; Al-Theeb, Abdulwahab; Zaman, Babar; Al-Djasim, Leyla; Craven, E. Randy; Edward, Deepak P.

2016-01-01

WHAT IS KNOWN AND OBJECTIVE: Physical bottle characteristics differ of brand name topical glaucoma medications and local generic equivalents. This study compares the bottle characteristics of international topical glaucoma brands versus local brands from the Kingdom of Saudi Arabia. METHODS: Data were collected on bottle drum volume, drop volume, bottle squeezability, bottle tip diameter, labels and instructions, cap color coding, and clarity of the drug label. Density-based calculations of drops in bottle volume were assessed using an analytic balance. Bottle tip diameter was measured using 0.05 mm Vernier calipers. A Likert scale-based questionnaire was used to evaluate the subjective opinions of patients on bottle squeezability, clarity of usage and storage instructions, and the consistency of the cap color coding. RESULTS: The volumes of international brands were statistically significantly higher than the local brands (P < 0.001). A number of drops per bottle and tip diameter were comparable between the international local brands. Cap color coding was inconsistent for international and local brands. Patients were dissatisfied with the label font size. Patients reported that the international and local brands were similar in terms of the ease of opening the bottle, instilling a drop, and the clarity of the instructions; but the local brands were subjectively easier to squeeze than international brands. WHAT IS NEW AND CONCLUSIONS: This is the first study to compare bottle characteristics of local Saudi Arabia brands with international brands. The bottle characteristics and patient feedback were similar between the local and international topical glaucoma medications. However, there were differences between the local and international brands in drug volume, bottle squeezability. Hence, patient compliance and drop dosage may differ based on the origin of manufacture. PMID:27994392

27 CFR 24.255 - Bottling or packing wine.

Code of Federal Regulations, 2010 CFR

2010-04-01

... in the same tax class when that wine is removed from bond, without benefit of tolerance, when the... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bottling or packing wine..., DEPARTMENT OF THE TREASURY LIQUORS WINE Storage, Treatment and Finishing of Wine Bottling, Packing, and...

Evaluation of microbial contamination of canine plasma eyedropper bottles following clinical use in canine patients.

PubMed

Strauss, Rachel A; Genschel, Ulrike; Allbaugh, Rachel A; Sebbag, Lionel; Ben-Shlomo, Gil

2018-05-24

To investigate microbial contamination of canine plasma eye drops when used clinically and to compare the effect of two different eyedropper bottles on contamination rate. Forty-six bottles containing plasma were randomly dispensed for use on 42 dogs with ulcerative keratitis. Of these, 23 were standard eyedropper bottles and 23 were Novelia ® bottles designed to prevent contamination. After use for up to 2 weeks, samples for bacterial culture were obtained from a drop of plasma, the bottle tip, the plasma inside the bottle, and the corneal surface. Fungal culture was performed from a drop of plasma. The overall microbial contamination rate was 17.4% (8/46 bottles); however, only one bottle had growth from the plasma inside the bottle. There was a lower contamination rate of Novelia ® bottles (3/23 = 13.0%) compared to standard bottles (5/23 = 21.7%), but this difference was not statistically significant (P = .57). There were also no significant differences in contamination rate of bottles used greater than 7 days compared to less than or equal to 7 days, or in bottles used greater than 4 times daily compared to 4 times daily or less. Three corneal samples (6.5%) had bacterial growth, but none matched contamination from the bottles. Novelia ® bottles may decrease contamination of plasma eye drops used clinically. However, while microbial contamination of plasma bottles was documented, no clinically relevant complications were observed. This study supports safe use of plasma eye drops for up to 2 weeks when refrigerated and dispensed from either Novelia ® or standard eyedropper bottles. © 2018 American College of Veterinary Ophthalmologists.

Tension amplification in tethered layers of bottle-brush polymers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leuty, Gary M.; Tsige, Mesfin; Grest, Gary S.

2016-02-26

In this paper, molecular dynamics simulations of a coarse-grained bead–spring model have been used to study the effects of molecular crowding on the accumulation of tension in the backbone of bottle-brush polymers tethered to a flat substrate. The number of bottle-brushes per unit surface area, Σ, as well as the lengths of the bottle-brush backbones N bb (50 ≤ N bb ≤ 200) and side chains N sc (50 ≤ N sc ≤ 200) were varied to determine how the dimensions and degree of crowding of bottle-brushes give rise to bond tension amplification along the backbone, especially near the substrate.more » From these simulations, we have identified three separate regimes of tension. For low Σ, the tension is due solely to intramolecular interactions and is dominated by the side chain repulsion that governs the lateral brush dimensions. With increasing Σ, the interactions between bottle-brush polymers induce compression of the side chains, transmitting increasing tension to the backbone. For large Σ, intermolecular side chain repulsion increases, forcing side chain extension and reorientation in the direction normal to the surface and transmitting considerable tension to the backbone.« less

Conical Refraction Bottle Beams for Entrapment of Absorbing Droplets.

PubMed

Esseling, Michael; Alpmann, Christina; Schnelle, Jens; Meissner, Robert; Denz, Cornelia

2018-03-22

Conical refraction (CR) optical bottle beams for photophoretic trapping of airborne absorbing droplets are introduced and experimentally demonstrated. CR describes the circular split-up of unpolarised light propagating along an optical axis in a biaxial crystal. The diverging and converging cones lend themselves to the construction of optical bottle beams with flexible entry points. The interaction of single inkjet droplets with an open or partly open bottle beam is shown implementing high-speed video microscopy in a dual-view configuration. Perpendicular image planes are visualized on a single camera chip to characterize the integral three-dimensional movement dynamics of droplets. We demonstrate how a partly opened optical bottle transversely confines liquid objects. Furthermore we observe and analyse transverse oscillations of absorbing droplets as they hit the inner walls and simultaneously measure both transverse and axial velocity components.

''Neither fish nor fowl'' EEC draft on bottle recycling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-05-20

It is reported that an EEC directive on drinks bottle recycling is expected to be announced shortly. The directive is expected to call for member countries to make arrangements for the compulsory return of beer and soft drinks bottles.

Improvements to the Whoosh Bottle Rocket Car Demonstration

ERIC Educational Resources Information Center

Campbell, Dean J.; Staiger, Felicia A.; Jujjavarapu, Chaitanya N.

2015-01-01

The whoosh bottle rocket car has been redesigned to be more reusable and more robust, making it even easier to use as a demonstration. Enhancements of this demonstration, including the use of heat sensitive ink and electronic temperature probes, enable users to find warmer and cooler regions on the surface of the whoosh bottle.

Association Between Bottle Size and Formula Intake in 2-Month-Old Infants.

PubMed

Wood, Charles T; Skinner, Asheley C; Yin, H Shonna; Rothman, Russell L; Sanders, Lee M; Delamater, Alan; Ravanbakht, Sophie N; Perrin, Eliana M

2016-04-01

To determine range of bottle sizes used and examine the relationship between bottle size and total daily consumption of infant formula. Cross-sectional analysis of baseline data collected as part of Greenlight, a cluster randomized trial to prevent childhood obesity at 4 pediatric resident clinics. The Greenlight study included healthy, term infants. For our analysis, parents of exclusively formula-fed infants reported volume per feed, number of feeds per day, and bottle size, which was dichotomized into small (<6 oz) or large (≥6 oz). We identified determinants of bottle size, and then examined relationships between bottle size and volume fed with log-transformed ordinary least squares regression, adjusting for infant age, sex, birth weight, current weight, race/ethnicity, and enrollment in Special Supplemental Nutrition Program for Women, Infants, and Children. Of 865 participants in the Greenlight study, 44% (n = 378; 21.8% white, 40.6% black, 35.3% Hispanic, 2.4% other) of infants were exclusively formula fed at 2 months. Median volume per day was 30 oz (interquartile range 12), and 46.0% of infants were fed with large bottles. Adjusted for covariates, parents using larger bottles reported feeding 4 oz more formula per day (34.2 oz, 95% confidence interval 33.5-34.9 vs 29.7 oz, 95% confidence interval 29.2-30.3, P = .03). Among exclusively formula-fed infants, use of a larger bottle is associated with parental report of more formula intake compared to infants fed with smaller bottles. If infants fed with larger bottles receive more formula, these infants may be overfed and consequently at risk for obesity. Copyright © 2016 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

Comparison of the Mineral Content of Tap Water and Bottled Waters

PubMed Central

Azoulay, Arik; Garzon, Philippe; Eisenberg, Mark J

2001-01-01

OBJECTIVES Because of growing concern that constituents of drinking water may have adverse health effects, consumption of tap water in North America has decreased and consumption of bottled water has increased. Our objectives were to 1) determine whether North American tap water contains clinically important levels of calcium (Ca2+), magnesium (Mg2+), and sodium (Na+) and 2) determine whether differences in mineral content of tap water and commercially available bottled waters are clinically important. DESIGN We obtained mineral analysis reports from municipal water authorities of 21 major North American cities. Mineral content of tap water was compared with published data regarding commercially available bottled waters and with dietary reference intakes (DRIs). MEASUREMENTS AND MAIN RESULTS Mineral levels varied among tap water sources in North America and among bottled waters. European bottled waters generally contained higher mineral levels than North American tap water sources and North American bottled waters. For half of the tap water sources we examined, adults may fulfill between 8% and 16% of their Ca2+ DRI and between 6% and 31% of their Mg2+ DRI by drinking 2 liters per day. One liter of most moderate mineralization European bottled waters contained between 20% and 58% of the Ca2+ DRI and between 16% and 41% of the Mg2+ DRI in adults. High mineralization bottled waters often contained up to half of the maximum recommended daily intake of Na+. CONCLUSION Drinking water sources available to North Americans may contain high levels of Ca2+, Mg2+, and Na+ and may provide clinically important portions of the recommended dietary intake of these minerals. Physicians should encourage patients to check the mineral content of their drinking water, whether tap or bottled, and choose water most appropriate for their needs. PMID:11318912

Process qualification and testing of LENS deposited AY1E0125 D-bottle brackets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atwood, Clinton J.; Smugeresky, John E.; Jew, Michael

2006-11-01

The LENS Qualification team had the goal of performing a process qualification for the Laser Engineered Net Shaping{trademark}(LENS{reg_sign}) process. Process Qualification requires that a part be selected for process demonstration. The AY1E0125 D-Bottle Bracket from the W80-3 was selected for this work. The repeatability of the LENS process was baselined to determine process parameters. Six D-Bottle brackets were deposited using LENS, machined to final dimensions, and tested in comparison to conventionally processed brackets. The tests, taken from ES1E0003, included a mass analysis and structural dynamic testing including free-free and assembly-level modal tests, and Haversine shock tests. The LENS brackets performedmore » with very similar characteristics to the conventionally processed brackets. Based on the results of the testing, it was concluded that the performance of the brackets made them eligible for parallel path testing in subsystem level tests. The testing results and process rigor qualified the LENS process as detailed in EER200638525A.« less

Breast vs bottle: endocrine responses are different with formula feeding.

PubMed

Lucas, A; Sarson, D L; Blackburn, A M; Adrian, T E; Aynsley-Green, A; Bloom, S R

1980-06-14

Differences in pancreatic and gut-hormone release between breast-fed and bottle-fed infants have not been documented although these hormones may play a key role in postnatal adaptation. In a study of 77 six-day-old healthy term infants, bottle-fed neonates ('Cow and Gate Premium') had significant changes in plasma-concentrations of insulin, motilin, enteroglucagon, neurotensin, and pancreatic polypeptide after feeding, whereas in breast-fed infants these changes were reduced or absent. Basal levels of gastric inhibitory polypeptide, motilin, neurotensin, and vasoactive intestinal peptide were also higher in the bottle-fed infants than in those who were breast-fed. These findings may partly explain differences in the deposition of subcutaneous fat and in stool frequency between breast-fed and bottle-fed neonates.

Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

PubMed Central

Schulte, Michael B; Draghi, Jeremy A; Plotkin, Joshua B; Andino, Raul

2015-01-01

Life history theory posits that the sequence and timing of events in an organism's lifespan are fine-tuned by evolution to maximize the production of viable offspring. In a virus, a life history strategy is largely manifested in its replication mode. Here, we develop a stochastic mathematical model to infer the replication mode shaping the structure and mutation distribution of a poliovirus population in an intact single infected cell. We measure production of RNA and poliovirus particles through the infection cycle, and use these data to infer the parameters of our model. We find that on average the viral progeny produced from each cell are approximately five generations removed from the infecting virus. Multiple generations within a single cell infection provide opportunities for significant accumulation of mutations per viral genome and for intracellular selection. DOI: http://dx.doi.org/10.7554/eLife.03753.001 PMID:25635405

Blood culture bottles are superior to conventional media for vitreous culture.

PubMed

Thariya, Patsuda; Yospaiboon, Yosanan; Sinawat, Suthasinee; Sanguansak, Thuss; Bhoomibunchoo, Chavakij; Laovirojjanakul, Wipada

2016-08-01

To compare blood culture bottles and conventional media for the vitreous culture in patients with clinically suspected infectious endophthalmitis. Retrospective comparative study at KKU Eye Center, Khon Kaen University. There were 342 patients with clinically suspected infectious endophthalmitis participated in the study. The vitreous specimens were inoculated in both blood culture bottles and on conventional culture media (blood agar, MacConkey agar, chocolate agar, Sabouraud dextrose agar and thioglycolate broth). The number of positive culture yields in both blood culture bottles and conventional media. Positive culture yields in both methods were found in 151 eyes (49.5%). There were 136 of 151 eyes (90.1%) with positive culture in blood culture bottles, whereas 99 of 151 eyes (65.6%) yielded positive cultures in conventional media. These findings were different with a statistical significance (P < 0.00001) and an odds ratio of 3.47 (95% confidence interval 1.92, 6.63). A combination of blood culture bottles and conventional media improved the yield. Blood culture bottles are superior to conventional media for vitreous culture in clinically suspected infectious endophthalmitis. Vitreous culture using blood culture bottles should be recommended as the primary method for microbiological diagnosis. A combination of both methods further improves the positive culture yield. © 2016 Royal Australian and New Zealand College of Ophthalmologists.

[Safety verification for reuse of PET and glass bottles].

PubMed

Hayashi, Eiichi; Imai, Toshio; Niimi, Hiroji

2011-01-01

In order to verify the safety associated with reusing PET and glass bottles, a challenge test was conducted with five surrogate contaminants: 1,1,1-trichloroethane, chlorobenzene, toluene, benzophenone and phenyl cyclohexane. Bottles were filled with a cocktail solution of these contaminants and stored at 50 °C for 7 days, then washed with water and alkaline solutions. Material and migration tests were conducted at each step. The material test results showed that 430-1,440 µg/g of the contaminants were retained after water washing, and that even after washing with a 3.5% NaOH solution, 225-925 µg/g of the contaminants were retained. The migration tests revealed that 0.095-7.35 µg/mL of the contaminants were eluted. Similar tests were conducted with a soft drink ingredient, limonene. The results revealed that 48 µg/g of limonene was retained even after washing with NaOH solution, and that 0.16 µg/mL of limonene was eluted. Conversely, no contaminants were eluted from glass bottles after washing with the NaOH solution. Thus, from the viewpoint of safety and the preservation of content quality, PET bottles are not considered suitable for reuse when compared with glass bottles.

Fluid dynamics following flow shut-off in bottle filling

NASA Astrophysics Data System (ADS)

Thete, Sumeet; Appathurai, Santosh; Gao, Haijing; Basaran, Osman

2012-11-01

Bottle filling is ubiquitous in industry. Examples include filling of bottles with shampoos and cleaners, engine oil and pharmaceuticals. In these examples, fluid flows out of a nozzle to fill bottles in an assembly line. Once the required volume of fluid has flowed out of the nozzle, the flow is shut off. However, an evolving fluid thread or string may remain suspended from the nozzle following flow shut-off and persist. This stringing phenomenon can be detrimental to a bottle filling operation because it can adversely affect line speed and filling accuracy by causing uncertainty in fill volume, product loss and undesirable marring of the bottles' exterior surfaces. The dynamics of stringing are studied numerically primarily by using the 1D, slender-jet approximation of the flow equations. A novel feature entails development and use of a new boundary condition downstream of the nozzle exit to expedite the computations. While the emphasis is on stringing of Newtonian fluids and use of 1D approximations, results will also be presented for situations where (a) the fluids are non-Newtonian and (b) the full set of equations are solved without invoking the 1D approximation. Phase diagrams will be presented that identify conditions for which stringing can be problematic.

Flutist Produces Four Resonances with a Single Bottle

ERIC Educational Resources Information Center

Ruiz, Michael J.; Boysen, Erika

2017-01-01

In a dramatic physics demonstration, a professional flutist produces four resonances with a 12 ounce Boylan soda bottle solely through her breath control. The 22cm bottle acts like a Helmholtz resonator for the lowest pitch. The three higher pitches fall near the 3rd, 5th, and 7th harmonics for a 22cm closed pipe. A video of this remarkable feat…

Ocular injuries from pressurised bottled drinks in China.

PubMed

Zhu, Lili; Lou, Dinghua

2014-01-01

The objective of this study is to provide a systematic review on ocular injuries induced by glass bottles containing carbonated drinks in China, which emphasised the injury circumstance and visual function loss. We performed a literature-based retrospective analysis using predetermined inclusion and exclusion criteria. Demographic characteristics of pressurised bottled drinks-related eye injuries were obtained and vision loss was calculated. A total of 26 relevant articles were found suitable for investigation of causative agent and patient demographics, of which 19 articles could be used for calculating vision loss and injury circumstance. Victims were often pertinent workers (46.0%). Most of the trauma was serious and even devastating. Final visual acuity was >10/20 in 29.2%, with severe final vision loss (<10/200) in 30.8%. Visual acuity can improve significantly with treatment (P<0.05). One in three ocular injuries from glass bottles containing carbonated drinks show severe vision loss. Relevant workers are most frequently injured, followed by inappropriate handlers or openers. Besides manufacturing standards being strictly implemented, many ocular traumas related to bottled carbonated drinks should be prevented through health education. Copyright © 2013 Elsevier Ltd. All rights reserved.

Heat Transfer in Glass, Aluminum, and Plastic Beverage Bottles

ERIC Educational Resources Information Center

Clark, William M.; Shevlin, Ryan C.; Soffen, Tanya S.

2010-01-01

This paper addresses a controversy regarding the effect of bottle material on the thermal performance of beverage bottles. Experiments and calculations that verify or refute advertising claims and represent an interesting way to teach heat transfer fundamentals are described. Heat transfer coefficients and the resistance to heat transfer offered…

27 CFR 31.203 - Possession of used liquor bottles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... emptied or elsewhere, including disposition for purposes that will result in the bottles being rendered... collectors' items or for other purposes not involving the packaging of any product for sale; (b) Any person may possess, offer for sale, or sell unusual or distinctive bottles for purposes not involving the...

27 CFR 31.203 - Possession of used liquor bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... emptied or elsewhere, including disposition for purposes that will result in the bottles being rendered... collectors' items or for other purposes not involving the packaging of any product for sale; (b) Any person may possess, offer for sale, or sell unusual or distinctive bottles for purposes not involving the...

27 CFR 31.203 - Possession of used liquor bottles.

Code of Federal Regulations, 2013 CFR

2013-04-01

... emptied or elsewhere, including disposition for purposes that will result in the bottles being rendered... collectors' items or for other purposes not involving the packaging of any product for sale; (b) Any person may possess, offer for sale, or sell unusual or distinctive bottles for purposes not involving the...

27 CFR 31.203 - Possession of used liquor bottles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... emptied or elsewhere, including disposition for purposes that will result in the bottles being rendered... collectors' items or for other purposes not involving the packaging of any product for sale; (b) Any person may possess, offer for sale, or sell unusual or distinctive bottles for purposes not involving the...

27 CFR 31.203 - Possession of used liquor bottles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... emptied or elsewhere, including disposition for purposes that will result in the bottles being rendered... collectors' items or for other purposes not involving the packaging of any product for sale; (b) Any person may possess, offer for sale, or sell unusual or distinctive bottles for purposes not involving the...

Filling or Draining a Water Bottle with Two Holes

ERIC Educational Resources Information Center

Cross, Rod

2016-01-01

Three simple experiments are described using a small water bottle with two holes in the side of the bottle. The main challenge is to predict and then explain the observations, but the arrangements can also be used for quantitative measurements concerning hydrostatic pressure, Bernoulli's equation, surface tension and bubble formation.

Modeling of in-use stability for tablets and powders in bottles.

PubMed

Waterman, Kenneth C; Chen, Lili; Waterman, Philip; MacDonald, Bruce C; Monahan, Andrew P; Scrivens, Garry

2016-10-01

A model is presented for determining the time when an active pharmaceutical ingredient in tablets/powders will remain within its specification limits during an in-use period; that is, when a heat-induction sealed bottle is opened for fixed time periods and where tablets are removed at fixed time points. This model combines the Accelerated Stability Assessment Program to determine the impact on degradation rates of relative humidity (RH) with calculations of the RH as a function of time for the dosage forms under in-use conditions. These calculations, in a conservative approach, assume that the air inside bottles with broached heat-induction seals completely exchanges with the external environment during periods when the bottle remains open. The solid dosages are assumed to sorb water at estimable rates during these openings. When bottles are capped, the moisture vapor transmission rate can be estimated to determine the changing RH inside the bottles between opening events. The impact of silica gel desiccants can also be included in the modeling.

27 CFR 25.158 - Tax computation for bottled beer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... bottled beer. 25.158 Section 25.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.158 Tax computation for bottled beer. Barrel equivalents for various case sizes are as follows: (a) For U.S. measure...

27 CFR 25.158 - Tax computation for bottled beer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... bottled beer. 25.158 Section 25.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.158 Tax computation for bottled beer. Barrel equivalents for various case sizes are as follows: (a) For U.S. measure...

27 CFR 25.158 - Tax computation for bottled beer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... bottled beer. 25.158 Section 25.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.158 Tax computation for bottled beer. Barrel equivalents for various case sizes are as follows: (a) For U.S. measure...

27 CFR 25.158 - Tax computation for bottled beer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... bottled beer. 25.158 Section 25.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.158 Tax computation for bottled beer. Barrel equivalents for various case sizes are as follows: (a) For U.S. measure...

27 CFR 25.158 - Tax computation for bottled beer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... bottled beer. 25.158 Section 25.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.158 Tax computation for bottled beer. Barrel equivalents for various case sizes are as follows: (a) For U.S. measure...

Community Responses to the Removal of Bottled Water on a University Campus

ERIC Educational Resources Information Center

Mikhailovich, Katja; Fitzgerald, Robert

2014-01-01

Purpose: This paper aimed to examine the impact of the removal of bottled water on the campus community. This paper presents the findings of a survey conducted at the first Australian university to remove single-use bottled water from sale on a small regional university campus. The removal of bottled water from sale at the university formed part…

Simple Model of a Rolling Water-Filled Bottle on an Inclined Ramp

ERIC Educational Resources Information Center

Lin, Shihao; Hu, Naiwen; Yao, Tianchen; Chu, Charles; Babb, Simona; Cohen, Jenna; Sangiovanni, Giana; Watt, Summer; Weisman, Danielle; Klep, James; Walecki, Wojciech J.; Walecki, Eve S.; Walecki, Peter S.

2015-01-01

We investigate a water-filled bottle rolling down an incline and ask the following question: is a rolling bottle better described by a model ignoring all internal motion where the bottle is approximated by a material point sliding down an incline, or is it better described by a rigid solid cylinder rolling down the incline without skidding? The…

Infant bottle propping among a low-income urban population in Mexico.

PubMed

Pérez-Escamilla, R; Segura-Millán, S; Dewey, K G

1995-06-01

The prevalence of bottle propping (permitting an infant to drink from a bottle unattended) and the determinants of this practice at 1 week and 4 months of life were studied in a selected sample of urban women in Hermosillo, Mexico. The sample (n = 165) consisted of mothers planning to breast-feed who gave birth to healthy infants at one of two public hospitals. Data were obtained by interviewing women shortly before they were discharged from the hospital and at about 1 week and 4 months postpartum. Among those mothers giving liquid breast milk substitutes to their infants, the percentage practicing bottle propping increased from 27% at 1 week (n = 20/74) to 67% at 4 months (n = 87/130). Women who practiced bottle propping at 1 week were significantly more likely to continue this practice at 4 months. Bottle propping was significantly more common, both at 1 week and 4 months, among women who had completely weaned their infants than among those who were still combining breast and formula feeding. Multivariate logistic regression indicated that 1-week risk factors for bottle propping were low socioeconomic status, being a multiparous single mother, and being a young mother (< or = 18 years old) with a female infant, while 4-month risk factors were complete weaning, delivery in a "nursery" (versus a "rooming-in") hospital, and lack of support by the mother's partner for breast-feeding. While the possible health risks associated with early bottle propping have not been well defined, the extent of the practice observed in this study suggests that such risks deserve further investigation.

Concentration of ions in selected bottled water samples sold in Malaysia

NASA Astrophysics Data System (ADS)

Aris, Ahmad Zaharin; Kam, Ryan Chuan Yang; Lim, Ai Phing; Praveena, Sarva Mangala

2013-03-01

Many consumers around the world, including Malaysians, have turned to bottled water as their main source of drinking water. The aim of this study is to determine the physical and chemical properties of bottled water samples sold in Selangor, Malaysia. A total of 20 bottled water brands consisting of `natural mineral (NM)' and `packaged drinking (PD)' types were randomly collected and analyzed for their physical-chemical characteristics: hydrogen ion concentration (pH), electrical conductivity (EC) and total dissolved solids (TDS), selected major ions: calcium (Ca), potassium (K), magnesium (Mg) and sodium (Na), and minor trace constituents: copper (Cu) and zinc (Zn) to ascertain their suitability for human consumption. The results obtained were compared with guideline values recommended by World Health Organization (WHO) and Malaysian Ministry of Health (MMOH), respectively. It was found that all bottled water samples were in accordance with the guidelines set by WHO and MMOH except for one sample (D3) which was below the pH limit of 6.5. Both NM and PD bottled water were dominated by Na + K > Ca > Mg. Low values for EC and TDS in the bottled water samples showed that water was deficient in essential elements, likely an indication that these were removed by water treatment. Minerals like major ions were present in very low concentrations which could pose a risk to individuals who consume this water on a regular basis. Generally, the overall quality of the supplied bottled water was in accordance to standards and guidelines set by WHO and MMOH and safe for consumption.

A comparison of bottles and snap traps for short-term small mammal sampling

Treesearch

James F. Taulman; Ronald E. Thill; T. Bently Wigley; M. Anthony Melchiors

1992-01-01

Bottles were tested as traps for small mammals. Used in conjunction with three types of snap traps over 30,240 trap nights, bottles captured eight (2%) of the total 421 mammals taken. Bottles were inefficient in capturing small mammals compared to snap traps.

Detection algorithm for glass bottle mouth defect by continuous wavelet transform based on machine vision

NASA Astrophysics Data System (ADS)

Qian, Jinfang; Zhang, Changjiang

2014-11-01

An efficient algorithm based on continuous wavelet transform combining with pre-knowledge, which can be used to detect the defect of glass bottle mouth, is proposed. Firstly, under the condition of ball integral light source, a perfect glass bottle mouth image is obtained by Japanese Computar camera through the interface of IEEE-1394b. A single threshold method based on gray level histogram is used to obtain the binary image of the glass bottle mouth. In order to efficiently suppress noise, moving average filter is employed to smooth the histogram of original glass bottle mouth image. And then continuous wavelet transform is done to accurately determine the segmentation threshold. Mathematical morphology operations are used to get normal binary bottle mouth mask. A glass bottle to be detected is moving to the detection zone by conveyor belt. Both bottle mouth image and binary image are obtained by above method. The binary image is multiplied with normal bottle mask and a region of interest is got. Four parameters (number of connected regions, coordinate of centroid position, diameter of inner cycle, and area of annular region) can be computed based on the region of interest. Glass bottle mouth detection rules are designed by above four parameters so as to accurately detect and identify the defect conditions of glass bottle. Finally, the glass bottles of Coca-Cola Company are used to verify the proposed algorithm. The experimental results show that the proposed algorithm can accurately detect the defect conditions of the glass bottles and have 98% detecting accuracy.

Assessment of metal contaminations leaching out from recycling plastic bottles upon treatments.

PubMed

Cheng, Xiaoliang; Shi, Honglan; Adams, Craig D; Ma, Yinfa

2010-08-01

Heavy metal contaminants in environment, especially in drinking water, are always of great concern due to their health impact. Due to the use of heavy metals as catalysts during plastic syntheses, particularly antimony, human exposure to metal release from plastic bottles has been a serious concern in recent years. The aim and scope of this study were to assess metal contaminations leaching out from a series of recycling plastic bottles upon treatments. In this study, leaching concentrations of 16 metal elements were determined in 21 different types of plastic bottles from five commercial brands, which were made of recycling materials ranging from no. 1 to no. 7. Several sets of experiments were conducted to study the factors that could potentially affect the metal elements leaching from plastic bottles, which include cooling with frozen water, heating with boiling water, microwave, incubating with low-pH water, outdoor sunlight irradiation, and in-car storage. Heating and microwave can lead to a noticeable increase of antimony leaching relative to the controls in bottle samples A to G, and some even reached to a higher level than the maximum contamination level (MCL) of the US Environmental Protection Agency (USEPA) regulations. Incubation with low-pH water, outdoor sunlight irradiation, and in-car storage had no significant effect on antimony leaching relative to controls in bottle samples A to G, and the levels of antimony leaching detected were below 6 ppb which is the MCL of USEPA regulations. Cooling had almost no effect on antimony leaching based on our results. For the other interested 15 metal elements (Al, V, Cr, Mn, Co, Ni, Cu, As, Se, Mo, Ag, Cd, Ba, Tl, Pb), no significant leaching was detected or the level was far below the MCL of USEPA regulations in all bottle samples in this study. In addition, washing procedure did contribute to the antimony leaching concentration for polyethylene terephthalate (PET) bottles. The difference of antimony leaching

In-cell SHAPE uncovers dynamic interactions between the untranslated regions of the foot-and-mouth disease virus RNA.

PubMed

Diaz-Toledano, Rosa; Lozano, Gloria; Martinez-Salas, Encarnacion

2017-02-17

The genome of RNA viruses folds into 3D structures that include long-range RNA–RNA interactions relevant to control critical steps of the viral cycle. In particular, initiation of translation driven by the IRES element of foot-and-mouth disease virus is stimulated by the 3΄UTR. Here we sought to investigate the RNA local flexibility of the IRES element and the 3΄UTR in living cells. The SHAPE reactivity observed in vivo showed statistically significant differences compared to the free RNA, revealing protected or exposed positions within the IRES and the 3΄UTR. Importantly, the IRES local flexibility was modified in the presence of the 3΄UTR, showing significant protections at residues upstream from the functional start codon. Conversely, presence of the IRES element in cis altered the 3΄UTR local flexibility leading to an overall enhanced reactivity. Unlike the reactivity changes observed in the IRES element, the SHAPE differences of the 3΄UTR were large but not statistically significant, suggesting multiple dynamic RNA interactions. These results were supported by covariation analysis, which predicted IRES-3΄UTR conserved helices in agreement with the protections observed by SHAPE probing. Mutational analysis suggested that disruption of one of these interactions could be compensated by alternative base pairings, providing direct evidences for dynamic long-range interactions between these distant elements of the viral genome.

Fluoride and bacterial content of bottled drinking water versus municipal tap water.

PubMed

Mythri, H; Chandu, G N; Prashant, G M; Subba Reddy, V V

2010-01-01

Water is a divine gift. People quench their thirst without questioning the source of water. But, apprehension about contaminants in municipal water supplies along with increased fear of fluorosis made bottled drinking water as one of the important tradable commodities. The objectives of the study were to determine and compare the fluoride and bacterial contents of commercially available bottled drinking water and municipal tap water in Davangere city, Karnataka. Fifty samples of 10 categories of bottled drinking water with different batch numbers were purchased and municipal water from different sources were collected. Fluoride levels were determined by an ion-selective electrode. Water was cultured quantitatively and levels of bacteria were calculated as colony-forming units (CFUs) per milliliter. Descriptive analysis of water samples for fluoride concentration was in the range of 0.07-0.33 for bottled drinking water, Bisleri showing the highest of 0.33. A comparison of the mean values of microbial count for bottled drinking water with that of municipal tap water showed no statistically significant difference, but was more than the standard levels along with the presence of fungus and maggots. The fluoride concentration was below the optimal level for both municipal tap water and bottled drinking water. CFUs were more than the recommended level in both municipal tap water and bottled drinking water.

Investigating the Stability of a Bottle Filled with Different Amounts of Fluid

ERIC Educational Resources Information Center

Pahwa, Gantavya; Pingali, Rushil G.; Khubchandani, Aashish K.; Roy, Ekansh; Mudaliyar, Roshni R.; Mudaliyar, Rajesh P.

2017-01-01

The aim of this paper is to investigate the stability of a bottle filled with different volumes of water, and to determine the angle at which it topples over for each volume of water. Data for the angle at which the bottle toppled were gathered experimentally using a cylindrical 1 litre bottle, and two theoretical models were then developed,…

Recycling policies and programmes for PET drink bottles in Mexico.

PubMed

Schwanse, Elvira

2011-09-01

Transition and emerging economies confront a steadily increasing generation of municipal solid waste in the form of disposable packaging. The following article reports the situation of soft drink bottles made of polyethylene terephthalate (PET) in Mexico. Since 2002 schemes following the European Green Dot principle have been partly implemented to place responsibility on the producer, mainly soft drink bottlers. Private stakeholders are responsible for national recovery activities. Meanwhile Government presence to promote recovery is absent. Of post-consumer PET 75% is exported, and the newly created bottle-to-bottle (BTB) PET industry is confronted with bottlenecks in their post-consumer PET supply.

Endocrine disruptors in bottled mineral water: total estrogenic burden and migration from plastic bottles.

PubMed

Wagner, Martin; Oehlmann, Jörg

2009-05-01

Food consumption is an important route of human exposure to endocrine-disrupting chemicals. So far, this has been demonstrated by exposure modeling or analytical identification of single substances in foodstuff (e.g., phthalates) and human body fluids (e.g., urine and blood). Since the research in this field is focused on few chemicals (and thus missing mixture effects), the overall contamination of edibles with xenohormones is largely unknown. The aim of this study was to assess the integrated estrogenic burden of bottled mineral water as model foodstuff and to characterize the potential sources of the estrogenic contamination. In the present study, we analyzed commercially available mineral water in an in vitro system with the human estrogen receptor alpha and detected estrogenic contamination in 60% of all samples with a maximum activity equivalent to 75.2 ng/l of the natural sex hormone 17beta-estradiol. Furthermore, breeding of the molluskan model Potamopyrgus antipodarum in water bottles made of glass and plastic [polyethylene terephthalate (PET)] resulted in an increased reproductive output of snails cultured in PET bottles. This provides first evidence that substances leaching from plastic food packaging materials act as functional estrogens in vivo. Our results demonstrate a widespread contamination of mineral water with xenoestrogens that partly originates from compounds leaching from the plastic packaging material. These substances possess potent estrogenic activity in vivo in a molluskan sentinel. Overall, the results indicate that a broader range of foodstuff may be contaminated with endocrine disruptors when packed in plastics.

Perceptions on the use of bottled water in restaurants in Harare's Central Business District (CBD)

NASA Astrophysics Data System (ADS)

Juba, Olivia Sakhile; Tanyanyiwa, Vincent Itai

2018-06-01

Bottled water use continues to expand worldwide and in the last two decades, a significant number of consumers have shifted from tap water to bottled water due to Cryptosporidium outbreaks. Bottled water consumption has increased in Harare due to erratic tap water supplies. Since 2011, forty bottled water brands have been banned because of failure to meet safety and quality standards due to contamination, unsuitable packaging, and wrong labelling. Nevertheless, the bottled water industry continues to thrive as local authorities fail to adequately purify municipal water. The study assessed the perceptions on drinking bottled water in restaurants within Harare's CBD. Demographic and social factors associated with bottled water users were established and the role and influence of stakeholders in bottling and distribution of water documented. A field survey through the administration of questionnaires to fifty restaurant users was carried out to assess the perceptions of people on the use of bottled water in terms of its safety and potential health benefits. Key informant interviews were conducted using a semi-structured interview with ten local water bottling companies as well as representatives from the Environmental Management Agency (EMA) and Standards Association of Zimbabwe (SAZ). Data were analysed using descriptive statistics and logistic regression analysis. Standard descriptive statistics were generated, with 95% confidence intervals (95% CIs). Consumers used bottled water as their primary drinking water source when they perceived that tap water was not safe. Perceptions of purity of water, bottled water convenience, and tap water unavailability seemed to determine consumption patterns among users. Females in the 18-48 age groups were more likely to think that bottled water was cleaner, safer, tasted better and was more convenient than tap water. Consumers regularly purchased bottled water for drinking and used bottled water as their primary drinking water

FE-Analysis of Stretch-Blow Moulded Bottles Using an Integrative Process Simulation

NASA Astrophysics Data System (ADS)

Hopmann, C.; Michaeli, W.; Rasche, S.

2011-05-01

The two-stage stretch-blow moulding process has been established for the large scale production of high quality PET containers with excellent mechanical and optical properties. The total production costs of a bottle are significantly caused by the material costs. Due to this dominant share of the bottle material, the PET industry is interested in reducing the total production costs by an optimised material efficiency. However, a reduced material inventory means decreasing wall thicknesses and therewith a reduction of the bottle properties (e.g. mechanical properties, barrier properties). Therefore, there is often a trade-off between a minimal bottle weight and adequate properties of the bottle. In order to achieve the objectives Computer Aided Engineering (CAE) techniques can assist the designer of new stretch-blow moulded containers. Hence, tools such as the process simulation and the structural analysis have become important in the blow moulding sector. The Institute of Plastics Processing (IKV) at RWTH Aachen University, Germany, has developed an integrative three-dimensional process simulation which models the complete path of a preform through a stretch-blow moulding machine. At first, the reheating of the preform is calculated by a thermal simulation. Afterwards, the inflation of the preform to a bottle is calculated by finite element analysis (FEA). The results of this step are e.g. the local wall thickness distribution and the local biaxial stretch ratios. Not only the material distribution but also the material properties that result from the deformation history of the polymer have significant influence on the bottle properties. Therefore, a correlation between the material properties and stretch ratios is considered in an integrative simulation approach developed at IKV. The results of the process simulation (wall thickness, stretch ratios) are transferred to a further simulation program and mapped on the bottles FE mesh. This approach allows a local

Wooden beverage cases cause little damage to bottle caps

Treesearch

R. Bruce Anderson; William C. Miller

1973-01-01

Wooden beverage cases cause little damage to aluminum resealable caps during distribution. A study at bottling plants and distribution warehouses showed that an average of 1 bottle out of 4,000 has cap damage. Most of the damage was attributed to handling at the warehouse and in transit. Some recommendations are given for improvement of wooden beverage cases to prevent...

Design and performance of a vacuum-bottle solid-state calorimeter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bracken, D.S.; Biddle, R.; Cech, R.

1997-11-01

EG and G Mound Applied Technologies calorimetry personnel have developed a small, thermos-bottle solid-state calorimeter, which is now undergoing performance testing at Los Alamos National Laboratory. The thermos-bottle solid-state calorimeter is an evaluation prototype for characterizing the heat output of small heat standards and other homogeneous heat sources. The current maximum sample size is 3.5 in. long with a diameter of 0.8 in. The overall size of the thermos bottle and thermoelectric cooling device is 9.25 in. high by 3.75 in. diameter and less than 3 lb. Coupling this unit with compact electronics and a laptop computer makes this calorimetermore » easily hand carried by a single individual. This compactness was achieved by servo controlling the reference temperature below room temperature and replacing the water bath used in conventional calorimeter design with the thermos-bottle insulator. Other design features will also be discussed. The performance of the calorimeter will be presented.« less

The consumption and recycling collection system of PET bottles: a case study of Beijing, China.

PubMed

Zhang, Hua; Wen, Zong-Guo

2014-06-01

After studying the recycling collection system of polyethylene terephthalate (PET) bottles worldwide, the authors conducted an intercept survey in Beijing. Two separate questionnaires were issued, one questionnaire to PET bottle consumers and one to PET bottle recyclers. In this study, consumers are defined as people that consume PET-bottled beverages in their daily life. Recyclers were defined as those involved in the collection and recycling of PET bottles. These include scavengers, itinerant waste buyers, small community waste-buying depots, medium/large redemption depots, and recycling companies. In total, 580 surveys were completed, including 461 by consumers and 119 by recyclers. The authors found that consumption of PET bottles in Beijing was nearly 100,000 tonnes in 2012. Age, occupation, gender, and education were identified as significant factors linked to PET-bottled beverage consumption, while income was not a significant factor. 90% Of post-consumed PET bottles were collected by informal collectors (i.e., scavengers and itinerant waste buyers). The survey also found that nearly all PET bottles were reprocessed by small factories that were not designed with pollution control equipment, which allows them to offer higher prices for waste recyclable bottles. As Beijing is trying to build a formal recycling collection system for recyclables, subsidies should be given to the formal recycling sector rather than being charged land use fees, and attention should also be given to informal recyclers that make their living from the collection of recyclables. Informal and formal sectors may work together by employing the scavengers and itinerant waste buyers for the formal sectors. In addition to the recycling of PET bottles, concern should also be allocated to reduce consumption, especially among young people, as they, compared to other groups, have a stronger demand for PET-bottled beverages and will be the main body of society. Copyright © 2013 Elsevier Ltd

27 CFR 19.384 - Preparation of bottling or packaging record.

Code of Federal Regulations, 2010 CFR

2010-04-01

... packaging record. 19.384 Section 19.384 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... Than Denaturation and Manufacture of Articles Bottling, Packaging, and Removal of Products § 19.384 Preparation of bottling or packaging record. The proprietor shall prepare a record for each batch of spirits...

Plasma sterilization of polyethylene terephthalate bottles by pulsed corona discharge at atmospheric pressure.

PubMed

Masaoka, Satoshi

2007-06-01

A pulsed power supply was used to generate a corona discharge on a polyethylene terephthalate bottle, to conduct plasma sterilization at atmospheric pressure. Before generating such a discharge, minute quantities of water were attached to the inner surface of the bottle and to the surface of a high voltage (HV) electrode inserted into the bottle. Next, high-voltage pulses of electricity were discharged between electrodes for 6.0s, while rotating the bottle. The resulting spore log reduction values of Bacillus subtilis and Aspergillus niger on the inner surface of the bottle were 5.5 and 6 or higher, respectively, and those on the HV electrode surface were each 6 or higher for both strains. The presence of the by-products gaseous ozone, hydrogen peroxide, and nitric ions resulting from the electrical discharge was confirmed.

Determination of water vapor transmission rate (WVTR) of HDPE bottles for pharmaceutical products.

PubMed

Chen, Yisheng; Li, Yanxia

2008-06-24

The objective of this study was to investigate the effects of experimental conditions for measuring the water vapor transmission rate (WVTR) of high-density polyethylene (HDPE) bottles using a steady-state sorption method. Bottles were filled with desiccant, closed with caps and heat induction sealed, and then stored in stability chambers at controlled temperature and relative humidity. Weight gain of the bottles was determined every 1 or 2 weeks until a linear weight gain profile was obtained. WVTR of the bottles was determined from the slope of the linear portion of the weight gain versus time profile. The effects of desiccants and temperature/humidity were studied. Results show that, with a sufficient amount of anhydrous calcium chloride in bottles, a negligibly low and sufficiently constant headspace humidity is maintained, and a steady-state permeation rate is achieved. For all 8 sizes of bottles used in this study, steady-state was achieved in 1 or 2 weeks after the experiment was started. This method provided reproducible WVTR data for HDPE bottles. Apparent moisture permeability of all 8 sizes of bottles was (2.3+/-0.3)x10(-7), (2.6+/-0.2)x10(-7), and (3.4+/-0.2)x10(-7)cm(2)/s at 25 degrees C, 30 degrees C, 40 degrees C, respectively. Moisture permeability determined from the current study was similar to data reported in the literature, indicating that the steady-state weight gain method can be used to obtain reliable WVTR of containers for pharmaceutical products.

Prevalence of baby bottle versus breastfeeding graphics on products in national chain stores.

PubMed

Gellerson, Daphne; Hornsby, Paige P; Lowenhaupt, Stephanie A; Bressler, Colleen J; Burns, Whitney R; Friedman, Caroline F; Vaughn, Natalie H; Marshall, Stephanie P; Marshall, Trisha L; Park, Jennie; Kellams, Ann

2012-12-01

This study surveyed the prevalence of bottle versus breastfeeding graphic images on products marketed for pregnant mothers and young children available for purchase in national chain stores. This was a product survey/content analysis. Eighteen national chain stores located in a 10-mile radius of Charlottesville, VA were visited. In total, 2,670 individual items in 11 categories of baby shower and baby gift merchandise (shower invitations, greeting cards, gift wrap, shower decorations, baby dolls, baby books, infant clothing, bibs, nursery decorations, baby blankets, and disposable diapers) were assessed. The main outcome measures were prevalences of baby bottle and breastfeeding graphic images. Baby bottle images were found on products in eight of the 11 categories of items surveyed. Thirty-five percent of baby dolls were marketed with a baby bottle. The prevalence of bottle images on items in all other categories, however, was low. Of the 2,670 items surveyed, none contained a breastfeeding image. The low prevalence of baby bottle images on commonly purchased baby gift and baby shower items is encouraging. However, the absence of breastfeeding images and the relatively high prevalence of baby dolls marketed with a baby bottle demonstrate that breastfeeding is not portrayed as the physiologic norm on these products. Product designers should explore ways to promote breastfeeding, consumers should make informed choices in product selection, and advocacy groups should promote guidelines for these products.

Mothers' experiences of bottle-feeding: a systematic review of qualitative and quantitative studies.

PubMed

Lakshman, R; Ogilvie, D; Ong, K K

2009-08-01

Most babies receive at least some formula milk. Variations in formula-feeding practices can have both short- and long-term health consequences. The literature on parents' experiences of bottle-feeding was systematically reviewed to understand how formula-feeding decisions are made. Relevant English-language papers, identified by searching 12 electronic databases, reference lists and related articles and by contacting first authors of included papers, were systematically searched for and appraised. The included studies were analysed and synthesised using a combination of narrative and thematic approaches. Consensus on the final inclusion, interpretation and synthesis of studies was reached across the research team. Six qualitative studies and 17 quantitative studies (involving 13 263 participants) were included. Despite wide differences in study design, context, focus and quality, several consistent themes emerged. Mothers who bottle-fed their babies experienced negative emotions such as guilt, anger, worry, uncertainty and a sense of failure. Mothers reported receiving little information on bottle-feeding and did not feel empowered to make decisions. Mistakes in preparation of bottle-feeds were common. No studies examined how mothers made decisions about the frequency or quantity of bottle-feeds. Inadequate information and support for mothers who decide to bottle-feed may put the health of their babies at risk. While it is important to promote breastfeeding, it is also necessary to ensure that the needs of bottle-feeding mothers are met.

Head Start Combats Baby Bottle Tooth Decay Among Native American Families.

ERIC Educational Resources Information Center

Phillips, Margaret G.; Stubbs, Phyllis E.

1987-01-01

Presents current developments concerning nursing bottle caries--"baby bottle tooth decay"--and spotlights a program funded by Head Start to reduce the prevalence of these painful and disfiguring, but preventable, children's dental diseases among American Indians and Alaska Native families. (Author/BB)

SmartStuff: A case study of a smart water bottle.

PubMed

Jovanov, Emil; Nallathimmareddygari, Vindhya R; Pryor, Jonathan E

2016-08-01

The rapid growth of Internet of Things (IoT) and miniature wearable biosensors have generated new opportunities for personalized eHealth and mHealth services. Smart objects equipped with physiological sensors can provide robust monitoring of activities of daily living and context for wearable physiological sensors. We present a case study of an intelligent water bottle that can precisely measure the amount of liquid in the bottle, monitor activity using inertial sensors, and physiological parameters using a touch and photoplethysmographic sensor. We evaluate two system configurations: a smart water bottle integrated into a personal body sensor network and a cloud based device. This paper presents system organization and the results from preliminary field testing of the prototype device.

Organochlorine pesticides residues in bottled drinking water from Mexico City.

PubMed

Díaz, Gilberto; Ortiz, Rutilio; Schettino, Beatriz; Vega, Salvador; Gutiérrez, Rey

2009-06-01

This work describes concentrations of organochlorine pesticides in bottled drinking water (BDW) in Mexico City. The results of 36 samples (1.5 and 19 L presentations, 18 samples, respectively) showed the presence of seven pesticides (HCH isomers, heptachlor, aldrin, and p,p'-DDE) in bottled water compared with the drinking water standards set by NOM-127-SSA1-1994, EPA, and World Health Organization. The concentrations of the majority of organochlorine pesticides were within drinking water standards (0.01 ng/mL) except for beta-HCH of BW 3, 5, and 6 samples with values of 0.121, 0.136, and 0.192 ng/mL, respectively. It is important monitoring drinking bottled water for protecting human health.

CELL SHAPE AND HEXOSE TRANSPORT IN NORMAL AND VIRUS-TRANSFORMED CELLS IN CULTURE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bissell, M.J.; Farson, D.; Tung, A.S.C.

1976-07-01

The rate of hexose transport was compared in normal and virus-transformed cells on a monolayer and in suspension. It was shown that: (1) Both trypsin-removed cells and those suspended for an additional day in methyl cellulose had decreased rates of transport and lower available water space when compared with cells on a monolayer. Thus, cell shape affects the overall rate of hexose transport, especially at higher sugar concentrations. (2) Even in suspension, the initial transport rates remained higher in transformed cells with reference to normal cells. Scanning electron micrographs of normal and transformed chick cells revealed morphological differences only inmore » the flat state. This indicates that the increased rate of hexose transport after transformation is not due to a difference in the shape of these cells on a monolayer. The relation between the geometry of cells, transport rates, and growth regulation is undoubtedly very complex, and our knowledge of these relationships is still very elementary. In a recent review on the influence of geometry on control of cell growth, Folkman and Greenspan (1) pointed out that the permeability of cells in a flat versus a spherical state may indeed be very different. The growth properties of cells on a surface and in suspension have been compared often (1-5). However, with one exception. little is known about the changes in transport properties when cell shape is changed. Foster and Pardee (6) demonstrated that the active transport of a-aminoisobutyric acid was reduced 2.5 times in suspension cultures of Chinese hamster cells with respect to the cells grown on a coverslip. They attributed this to the smaller surface area of suspended cells. While it is not clear why active transport should be dependent on the surface area available, it is possible that once the cells assume a spherical configuration, the carrier proteins are redistributed in such a way as to make them less accessible to the substrate. What happens to

A novel marsupial hepatitis A virus corroborates complex evolutionary patterns shaping the genus Hepatovirus.

PubMed

de Oliveira Carneiro, Ianei; Sander, Anna-Lena; Silva, Namá; Moreira-Soto, Andres; Normann, Andrea; Flehmig, Bertram; Lukashev, Alexander N; Dotzauer, Andreas; Wieseke, Nicolas; Franke, Carlos Roberto; Drexler, Jan Felix

2018-04-25

The discovery of nonprimate hepatoviruses illuminated the evolutionary origins of hepatitis A virus (HAV) in small mammals. Marsupials are ancient mammals that diverged during the Jurassic from other Eutheria. Viruses from marsupials may thus provide important insight into virus evolution. To investigate Hepatovirus macroevolutionary patterns, we sampled 112 opossums in northeastern Brazil. A novel marsupial HAV (MHAV) was detected in a Brazilian Common Opossum ( Didelphis aurita ) by nested RT-PCR. MHAV concentration in liver was high at 2.5x10 9 RNA copies/gram and about 1000-fold higher than in other solid organs, suggesting hepatotropism. Hepatovirus seroprevalence in D. aurita was 26.6% using an ELISA. End-point titers in confirmatory immunofluorescence assays were high and marsupial antibodies co-localized with anti-HAV control sera, suggesting specificity of serological detection. MHAV showed all genomic hallmarks defining hepatoviruses, including late domain motifs likely involved in quasi-envelope acquisition, a predicted C-terminal pX extension of VP1, strong avoidance of CpG dinucleotides and a type 3 internal ribosomal entry site. Translated polyprotein gene sequence distances of at least 23.7% to other hepatoviruses suggested MHAV represents a novel Hepatovirus species. Conserved predicted cleavage sites suggested similarities in polyprotein processing between HAV and MHAV. MHAV was nested within rodent hepatoviruses in phylogenetic reconstructions, suggesting an ancestral hepatovirus host switch from rodents into marsupials. Co-phylogenetic reconciliations of host and hepatovirus phylogenies confirmed that host-independent macroevolutionary patterns shaped the phylogenetic relationships of extant hepatoviruses. Although Marsupials are synanthropic and consumed as wild game in Brazil, HAV community protective immunity may limit the zoonotic potential of MHAV. IMPORTANCE The hepatitis A virus (HAV) is an ubiquitous cause of acute hepatitis in humans

"Bottled or Tap?" A Controversy for Science, Economics, and Society

ERIC Educational Resources Information Center

Lapham, Steven S.

2009-01-01

Every year, Americans spend billions of dollars on bottled water. They purchase a bottle from the vending machine or buy a case at the grocery, no longer considering the water that's freely available from their taps. As consumers and as citizens, however, Americans should pause to study the personal and public consequences of this choice. In this…

Eukaryotic-Like Virus Budding in Archaea

PubMed Central

Quemin, Emmanuelle R. J.; Chlanda, Petr; Sachse, Martin; Forterre, Patrick

2016-01-01

ABSTRACT Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored. Here, we used dual-axis electron tomography (ET) to characterize the morphogenesis of Sulfolobus spindle-shaped virus 1 (SSV1), the prototype of the family Fuselloviridae and representative of the most abundant archaea-specific group of viruses. Our results show that SSV1 assembly and egress are concomitant and occur at the cellular cytoplasmic membrane via a process highly reminiscent of the budding of enveloped viruses that infect eukaryotes. The viral nucleoprotein complexes are extruded in the form of previously unknown rod-shaped intermediate structures which have an envelope continuous with the host membrane. Further maturation into characteristic spindle-shaped virions takes place while virions remain attached to the cell surface. Our data also revealed the formation of constricted ring-like structures which resemble the budding necks observed prior to the ESCRT machinery-mediated membrane scission during egress of various enveloped viruses of eukaryotes. Collectively, we provide evidence that archaeal spindle-shaped viruses contain a lipid envelope acquired upon budding of the viral nucleoprotein complex through the host cytoplasmic membrane. The proposed model bears a clear resemblance to the egress strategy employed by enveloped eukaryotic viruses and raises important questions as to how the archaeal single-layered membrane composed of tetraether lipids can undergo scission. PMID:27624130

Ocular injuries from exploding glass-bottled Coca-Cola® drinks in Port Harcourt, Nigeria.

PubMed

Pedro-Egbe, Chinyere Nnenne; Ejimadu, Chibuike Sydney; Nwachukwu, Henrietta

2011-01-01

Eye injuries and subsequent loss of vision from the glass and caps of exploding pressurized bottled drinks have been well reported, and as a result most developed countries now use mainly plastic bottles. In Nigeria, however, most drinks are still sold in glass bottles and ocular injuries from this source are therefore not uncommon. To retrospectively analyze ocular injuries resulting from exploding glass-bottled Coca-Cola® and propose ways of eliminating such injuries in future. Eye Clinic, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. The medical records of all cases of ocular injury that presented at the Eye Clinic of the University of Port Harcourt Teaching Hospital over a 5-year period (January 2006 to December 2010) were retrieved and relevant data including age, sex, occupation, events surrounding bottle explosion, and type of ocular injury sustained were extracted. A total of 426 cases of ocular injuries was seen during the period under review. There were 335 (78.6%) males and 91 (21.4%) females. Six patients had ocular injury from exploding glass-bottled Coca-Cola®, giving an incidence of 1.4%. The presenting visual acuities (VA) were light perception (2 cases), counting fingers (2 cases), and 1 VA of 6/24 and 1 VA of 6/12. There were 4 (66.7%) cases of corneoscleral laceration with uveal prolapse and 1 case of total hyphema. Because pressurized glass-bottles can explode with normal handling, legislation to ban the use of glass containers for bottling carbonated drinks will go a long way to reducing ocular morbidity from this source. Plastic bottles should be introduced as an alternative.

Public perception and economic implications of bottled water consumption in underprivileged urban areas.

PubMed

Massoud, M A; Maroun, R; Abdelnabi, H; Jamali, I I; El-Fadel, M

2013-04-01

This paper presents a comparative assessment of public perception of drinking water quality in two underprivileged urban areas in Lebanon and Jordan with nearly similar cultural and demographic characteristics. It compares the quality of bottled water to the quality of the drinking water supplied through the public network and examines the economic implications of bottled water consumption in the two study areas. Participants' perception of the quality of drinking water provided via the public network was generally negative, and bottled water was perceived to be of better quality in both areas, thus affecting drinking water preferences and consumption patterns. The results reveal that the quality of bottled water is questionable in areas that lack enforcement of water quality standards, thus adding to the burden of an already disadvantaged community. Both areas demonstrated a considerable cost incurred for purchasing bottled water in low income communities reaching up to 26 % of total income.

Uniform irradiation of irregularly shaped cavities for photodynamic therapy.

PubMed

Rem, A I; van Gemert, M J; van der Meulen, F W; Gijsbers, G H; Beek, J F

1997-03-01

It is difficult to achieve a uniform light distribution in irregularly shaped cavities. We have conducted a study on the use of hollow 'integrating' moulds for more uniform light delivery of photodynamic therapy in irregularly shaped cavities such as the oral cavity. Simple geometries such as a cubical box, a sphere, a cylinder and a 'bottle-neck' geometry have been investigated experimentally and the results have been compared with computed light distributions obtained using the 'radiosity method'. A high reflection coefficient of the mould and the best uniform direct irradiance possible on the inside of the mould were found to be important determinants for achieving a uniform light distribution.

Relieving Dry Mouth: Varying Levels of pH Found in Bottled Water.

PubMed

Fisher, Bailey Jean; Spencer, Angela; Haywood, Van; Konchady, Gayathri

2017-07-01

It is estimated that 30% of people older than 60 years suffer from hyposalivation or dry mouth. Drinking water frequently has been recommended as a safe, non-pharmacologic way to combat hyposalivation. The saliva in patients with dry mouth is acidic. Beverages consumed daily may have an erosive potential on teeth. The pH and the mineral content of the beverage determine its erosive potential. An acidic beverage, therefore, may have harmful effects on mineralized tooth structures, causing erosion of enamel, dentin, and cementum. Because bottled water is both convenient and easily available, the authors tested the pH of eight common brands of bottled water. (One brand included two different bottle types, for a total of nine bottled waters tested.) To standardize the pH electrode, pH buffers of 4.7 and 10 were used. The pH was measured using the Denver Instruments basic pH meter. Six recordings were used for each brand and then averaged to report the pH. Two of the bottled water samples tested were below the critical level of 5.2 pH to 5.5 pH, the level at which erosion of enamel occurs. Six of the samples tested were below the critical pH of 6.8, at which erosion of root dentin occurs. The authors conclude that both patients and clinicians incorrectly presume bottled water to be innocuous. Clinicians should be cognizant of the erosive potential of different brands of bottled water to both educate patients and to recommend water with neutral or alkaline pH for patients with symptoms of dry mouth to prevent further deterioration and demineralization of tooth structure.

Design, Development and Testing of Inconel Alloy IN718 Spherical Gas Bottle for Oxygen Storage

NASA Astrophysics Data System (ADS)

Chenna Krishna, S.; Agilan, M.; Sudarshan Rao, G.; Singh, Satish Kumar; Narayana Murty, S. V. S.; Venkata Narayana, Ganji; Beena, A. P.; Rajesh, L.; Jha, Abhay K.; Pant, Bhanu

2017-11-01

This paper describes the details of design, manufacture and testing of 200 mm diameter spherical gas bottle of Inconel 718 (IN718) with nominal wall thickness of 2.3 mm. Gas bottle was designed for the specified internal pressure loading with a thickness of 2.9 mm at the circumferential weld which was brought down to 2.3 mm at the membrane locations. Hemispherical forgings produced through closed-die hammer forging were machined and electron beam welded to produce a spherical gas bottle. Duly welded gas bottle was subjected to standard aging treatment to achieve the required tensile strength. Aged gas bottle was inspected for dimensions and other stringent quality requirements using various nondestructive testing techniques. After inspection, gas bottle was subjected to pressure test for maximum expected operating pressure and proof pressure of 25 and 37.5 MPa, respectively. Strain gauges were bonded at different locations on the gas bottle to monitor the strains during the pressure test and correlated with the predicted values. The predicted strain matched well with the experimental strain confirming the design and structural integrity.

Accessories modifying based on plastic waste of shampoo bottle as home economic product

NASA Astrophysics Data System (ADS)

Setyowati, Erna; Sukesi, Siti

2018-03-01

Plastic is a waste that can not decompose by the soil and if its left without a good handling can pollute the environment. Plastic waste needs processing by the recycle bottles principle. Shampoo bottle is one of plastic waste with high density polyethylene type (HDPE). One of the innovation to recycling shampoo bottles waste into the new products whichbeneficially and aestheticallyform by engineered the buns accesories. Accessories are one of the tools used by most women, in the form of trinkets or ornaments which ajusted to the trend to beautify the look. Accessories from shampoo bottle waste can be obtained from household waste, beauty salon and the beauty program study by inculcating human beings' behavior by transforming waste into blessing while also increasing family income. Technique of making its by compiling through improvement of panelist team. The goal of this research is to engineering theaccessories based on shampoo bottle waste as home economics. The method are using experiment, observation and documentation, analysis using descriptive. The results obtained from the overall sensory test averaged at 93%, while the favored test averaged at 85.5%. The product can be ordered according to the desired design, but it takes a long time. Therefore accessories engineering from shampoo bottles waste-based can be used as home economics. The production of shampoo bottles waste-based accessories should improved its quality and quantity, to be marketed through the community, by the cooperation with accessories and bun craftsmen.

Bacteriological quality of bottled drinking water versus municipal tap water in Dharan municipality, Nepal.

PubMed

Pant, Narayan Dutt; Poudyal, Nimesh; Bhattacharya, Shyamal Kumar

2016-06-07

Water-related diseases are of great concern in developing countries like Nepal. Every year, there are countless morbidity and mortality due to the consumption of unsafe drinking water. Recently, there have been increased uses of bottled drinking water in an assumption that the bottled water is safer than the tap water and its use will help to protect from water-related diseases. So, the main objective of this study was to analyze the bacteriological quality of bottled drinking water and that of municipal tap water. A total of 100 samples (76 tap water and 24 bottled water) were analyzed for bacteriological quality and pH. The methods used were spread plate method for total plate count (TPC) and membrane filter method for total coliform count (TCC), fecal coliform count (FCC), and fecal streptococcal count (FSC). pH meter was used for measuring pH. One hundred percent of the tap water samples and 87.5 % of the bottled water samples were found to be contaminated with heterotrophic bacteria. Of the tap water samples, 55.3 % were positive for total coliforms, compared with 25 % of the bottled water. No bottled water samples were positive for fecal coliforms and fecal streptococci, in contrast to 21.1 % and 14.5 % of the tap water samples being contaminated with fecal coliforms and fecal streptococci, respectively. One hundred percent of the tap water samples and 54.2 % of the bottled water samples had pH in the acceptable range. All of the municipal tap water samples and most of the bottled drinking water samples distributed in Dharan municipality were found to be contaminated with one or more than one type of indicator organisms. On the basis of our findings, we may conclude that comparatively, the bottled drinking water may have been safer (than tap water) to drink.

Bottled Water Everywhere: Keeping it Safe

MedlinePlus

... that taps an aquifer—layers of porous rock, sand, and earth that contain water—which is under ... it to be labeled as “purified water.” Ensuring Quality and Safety Federal quality standards for bottled water ...

Impact of an alcohol-based hand sanitizer intervention on the spread of viruses in homes.

PubMed

Tamimi, Akrum H; Carlino, Sheri; Edmonds, Sarah; Gerba, Charles P

2014-06-01

The objectives of this study were to determine the movement of a virus throughout a household and the impact of an alcohol-based hand sanitizer (ABHS) on reducing the movement and exposure of the virus to household members. Bacterial virus MS-2 was used as the surrogate for human enteric and respiratory viruses. Seven households with families having at least two children in the age range of 2-18 living in the home were used in this study. The hands of one adult family member were contaminated with 1 × 10(8). MS-2 bacteriophage in each home. After 8 h, the hands of each family member (10 fingers) and 20 frequently touched fomites were sampled to determine baseline contamination without intervention. Within 8 h, MS-2 was detected on all of the family member's hands and most of the fomites. The intervention consisted of providing the families in all selected homes with bottles of an ABHS, which were placed in the kitchen, bathrooms, and nurseries. Smaller individual bottles were provided for each family member greater than 12 years old to place in purses, pockets, backpacks, etc. The families were instructed to use the ABHS one time or three times during the day. For one and three uses, a statistically significant reduction of virus on un-inoculated and inoculated hands of ~99% occurred within 8 h. Similar reductions occurred on fomites throughout the households (97-99%). These results demonstrate that the use of an ABHS can significantly reduce transfer of a virus to the hands, and to the commonly touched surfaces within the household.

Bottle-feeding practices during early infancy and eating behaviors at 6 years of age.

PubMed

Li, Ruowei; Scanlon, Kelley S; May, Ashleigh; Rose, Chelsea; Birch, Leann

2014-09-01

Evidence suggests an association of breastfeeding with a maternal feeding style (MFS) that is less controlling than formula feeding, which, in turn, may improve a child's self-regulation of eating. This study examines associations of bottle-feeding practices during infancy with MFS and children's eating behavior (CEB) at 6 years old. We linked data from the Infant Feeding Practices Study II to the Year 6 Follow-Up, which include 8 MFS and CEB measures adapted from previous validated instruments. Bottle-feeding practices during the first 6 months estimated by using the Infant Feeding Practices Study II were bottle-feeding intensity (BFI), mother's encouragement of infant to finish milk in the bottle, and infant finishing all milk in the bottle. Adjusted odds ratios (aORs) for associations of bottle-feeding practices with MFS and CEB at 6 years old were calculated by using multivariable logistic regressions controlling for sociodemographic characteristics and other feeding practices (N = 1117). Frequent bottle emptying encouraged by mothers during infancy increased odds of mothers encouraging their child to eat all the food on their plate (aOR: 2.37; 95% confidence interval [CI]: 1.65-3.41] and making sure their child eats enough (aOR: 1.62; 95% CI: 1.14-2.31) and of children eating all the food on their plate at 6 years old (aOR: 2.01; 95% CI: 1.05-3.83). High BFI during early infancy also increased the odds of mothers being especially careful to ensure their 6-year-old eats enough. Bottle-feeding practices during infancy may have long-term effects on MFS and CEB. Frequent bottle emptying encouraged by mothers and/or high BFI during early infancy increased the likelihood of mothers pressuring their 6-year-old child to eat and children's low satiety responsiveness. Copyright © 2014 by the American Academy of Pediatrics.

Ocular injuries from exploding glass-bottled Coca-Cola® drinks in Port Harcourt, Nigeria

PubMed Central

Pedro-Egbe, Chinyere Nnenne; Ejimadu, Chibuike Sydney; Nwachukwu, Henrietta

2011-01-01

Background: Eye injuries and subsequent loss of vision from the glass and caps of exploding pressurized bottled drinks have been well reported, and as a result most developed countries now use mainly plastic bottles. In Nigeria, however, most drinks are still sold in glass bottles and ocular injuries from this source are therefore not uncommon. Aim: To retrospectively analyze ocular injuries resulting from exploding glass-bottled Coca-Cola® and propose ways of eliminating such injuries in future. Setting: Eye Clinic, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. Materials and methods: The medical records of all cases of ocular injury that presented at the Eye Clinic of the University of Port Harcourt Teaching Hospital over a 5-year period (January 2006 to December 2010) were retrieved and relevant data including age, sex, occupation, events surrounding bottle explosion, and type of ocular injury sustained were extracted. Results: A total of 426 cases of ocular injuries was seen during the period under review. There were 335 (78.6%) males and 91 (21.4%) females. Six patients had ocular injury from exploding glass-bottled Coca-Cola®, giving an incidence of 1.4%. The presenting visual acuities (VA) were light perception (2 cases), counting fingers (2 cases), and 1 VA of 6/24 and 1 VA of 6/12. There were 4 (66.7%) cases of corneoscleral laceration with uveal prolapse and 1 case of total hyphema. Conclusion: Because pressurized glass-bottles can explode with normal handling, legislation to ban the use of glass containers for bottling carbonated drinks will go a long way to reducing ocular morbidity from this source. Plastic bottles should be introduced as an alternative. PMID:21629570

The Unintended Consequences of Changes in Beverage Options and the Removal of Bottled Water on a University Campus.

PubMed

Berman, Elizabeth R; Johnson, Rachel K

2015-07-01

We investigated how the removal of bottled water along with a minimum healthy beverage requirement affected the purchasing behavior, healthiness of beverage choices, and consumption of calories and added sugars of university campus consumers. With shipment data as a proxy, we estimated bottled beverage consumption over 3 consecutive semesters: baseline (spring 2012), when a 30% healthy beverage ratio was enacted (fall 2012), and when bottled water was removed (spring 2013) at the University of Vermont. We assessed changes in number and type of beverages and per capita calories, total sugars, and added sugars shipped. Per capita shipments of bottles, calories, sugars, and added sugars increased significantly when bottled water was removed. Shipments of healthy beverages declined significantly, whereas shipments of less healthy beverages increased significantly. As bottled water sales dropped to zero, sales of sugar-free beverages and sugar-sweetened beverages increased. The bottled water ban did not reduce the number of bottles entering the waste stream from the university campus, the ultimate goal of the ban. With the removal of bottled water, consumers increased their consumption of less healthy bottled beverages.

Predicting water filter and bottled water use in Appalachia: a community-scale case study.

PubMed

Levêque, Jonas G; Burns, Robert C

2017-06-01

A questionnaire survey was conducted in order to assess residents' perceptions of water quality for drinking and recreational purposes in a mid-sized city in northcentral West Virginia. Two logistic regression analyses were conducted in order to investigate the factors that influence bottle use and filter use. Results show that 37% of respondents primarily use bottled water and that 58% use a household filter when drinking from the tap. Respondents with lower levels of environmental concern, education levels, and lower organoleptic perceptions were most likely to perceive health risks from tap water consumption, and were most likely to use bottled water. Income, age, and organoleptic perceptions were predictors of water filter use among respondents. Clean water for recreational purposes was not found to be significant with either of these models. Our results demonstrate that bottle use and filter use are explained differently. We argue that more education and better communication about local tap water quality would decrease the use of bottled water. We demonstrate that household filters could be used as an alternative to bottled water.

[A norovirus-borne outbreak caused by contaminated bottled spring water in a school, Zhejiang province].

PubMed

Shen, Ji-chuan; Lin, Jun-fen; Gao, Jie; Yao, Wen-ting; Wen, Dong; Liu, Guang-tao; Han, Jian-kang; Ma, Hui-lai; Zhang, Li-jie; Zhu, Bao-ping

2011-08-01

To study a local hospital reported acute gastroenteritis in a boarding school on its source of infection, mode of transmission and risk factors of the infection. A suspected case was defined as who had developed diarrhea (≥ 3 times/day) or vomiting among teachers or students of the school, during April 19 - 30, 2010. A confirmed case was from a probable case plus tested positive for norovirus in stool specimens by using RT-PCR. Stool specimens of cases and environmental specimens were collected for laboratory diagnosis. In a case-control study, we compared exposures to sources of bottled water, consumption of bottled water, and hygienic habits of 220 probable or confirmed cases from April 21 - 23 in the peak of the outbreak, together with another 220 controls, with frequency-matched by school grade. 20.3% of the 1536 students but none of the teachers developed the disease. 98.6% of the cases (n = 217) and 85.5% (n = 188) of the controls had drunk bottled water in the classroom (OR(M-H) = 12.3, 95%CI: 3.7 - 40.9). 47.9% (n = 104) of the cases and 41.5% (n = 78) of the controls had drunk unboiled bottled water in classroom (OR(M-H) = 3.8, 95%CI: 1.5 - 9.6). 47.9% (n = 104) of the cases and 48.4% (n = 91) of the controls had drunk bottled mixed water (boiled and unboiled) in the classroom (OR(M-H) = 2.8, 95%CI: 1.1 - 7.0). Stool specimens from 3 cases and one bottle of uncovered bottled water in classroom showed positive of having norovirus genotype II. Coliforms was cultured much higher rates than standard deviations in the bottled water. The factory making the bottled water was not licensed or having strict disinfection facilities. Bottled spring water contaminated by norovirus was responsible for this outbreak.

Antimony leaching from polyethylene terephthalate (PET) plastic used for bottled drinking water.

PubMed

Westerhoff, Paul; Prapaipong, Panjai; Shock, Everett; Hillaireau, Alice

2008-02-01

Antimony is a regulated contaminant that poses both acute and chronic health effects in drinking water. Previous reports suggest that polyethylene terephthalate (PET) plastics used for water bottles in Europe and Canada leach antimony, but no studies on bottled water in the United States have previously been conducted. Nine commercially available bottled waters in the southwestern US (Arizona) were purchased and tested for antimony concentrations as well as for potential antimony release by the plastics that compose the bottles. The southwestern US was chosen for the study because of its high consumption of bottled water and elevated temperatures, which could increase antimony leaching from PET plastics. Antimony concentrations in the bottled waters ranged from 0.095 to 0.521 ppb, well below the US Environmental Protection Agency (USEPA) maximum contaminant level (MCL) of 6 ppb. The average concentration was 0.195+/-0.116 ppb at the beginning of the study and 0.226+/-0.160 ppb 3 months later, with no statistical differences; samples were stored at 22 degrees C. However, storage at higher temperatures had a significant effect on the time-dependent release of antimony. The rate of antimony (Sb) release could be fit by a power function model (Sb(t)=Sb 0 x[Time, h]k; k=8.7 x 10(-6)x[Temperature ( degrees C)](2.55); Sb 0 is the initial antimony concentration). For exposure temperatures of 60, 65, 70, 75, 80, and 85 degrees C, the exposure durations necessary to exceed the 6 ppb MCL are 176, 38, 12, 4.7, 2.3, and 1.3 days, respectively. Summertime temperatures inside of cars, garages, and enclosed storage areas can exceed 65 degrees C in Arizona, and thus could promote antimony leaching from PET bottled waters. Microwave digestion revealed that the PET plastic used by one brand contained 213+/-35 mgSb/kg plastic; leaching of all the antimony from this plastic into 0.5L of water in a bottle could result in an antimony concentration of 376 ppb. Clearly, only a small

Assessment of bisphenol A released from reusable plastic, aluminium and stainless steel water bottles.

PubMed

Cooper, James E; Kendig, Eric L; Belcher, Scott M

2011-10-01

Bisphenol A (BPA) is a ubiquitous high volume industrial chemical that is an estrogen and an environmental endocrine disrupting chemical. Bisphenol A is used extensively in the production of consumer goods, polycarbonate plastics, epoxy resins and coatings used to line metallic food and beverage cans. There is great concern regarding the possible harmful effects from exposures that result from BPA leaching into foods and beverages from packaging or storage containers. The objective of this study was to independently assess whether BPA contamination of water was occurring from different types of reusable drinking bottles marketed as alternatives to BPA-containing polycarbonate plastics. Using a sensitive and quantitative BPA-specific competitive enzyme-linked immunosorbent assay we evaluated whether BPA migrated into water stored in polycarbonate or copolyester plastic bottles, and different lined or unlined metallic reusable water bottles. At room temperature the concentration of BPA migrating from polycarbonate bottles ranged from 0.2 to 0.3 mg L⁻¹. Under identical conditions BPA migration from aluminium bottles lined with epoxy-based resins was variable depending on manufacturer ranging from 0.08 to 1.9 mg L⁻¹. Boiling water significantly increased migration of BPA from the epoxy lined bottles. No detectable BPA contamination was observed in water stored in bottles made from Tritan™ copolyester plastic, uncoated stainless steel, or aluminium lined with EcoCare™. The results from this study demonstrate that when used according to manufacturers' recommendations reusable water bottles constructed from "BPA-free" alternative materials are suitable for consumption of beverages free of BPA contamination. Copyright © 2011 Elsevier Ltd. All rights reserved.

Laboratory Workflow Analysis of Culture of Periprosthetic Tissues in Blood Culture Bottles.

PubMed

Peel, Trisha N; Sedarski, John A; Dylla, Brenda L; Shannon, Samantha K; Amirahmadi, Fazlollaah; Hughes, John G; Cheng, Allen C; Patel, Robin

2017-09-01

Culture of periprosthetic tissue specimens in blood culture bottles is more sensitive than conventional techniques, but the impact on laboratory workflow has yet to be addressed. Herein, we examined the impact of culture of periprosthetic tissues in blood culture bottles on laboratory workflow and cost. The workflow was process mapped, decision tree models were constructed using probabilities of positive and negative cultures drawn from our published study (T. N. Peel, B. L. Dylla, J. G. Hughes, D. T. Lynch, K. E. Greenwood-Quaintance, A. C. Cheng, J. N. Mandrekar, and R. Patel, mBio 7:e01776-15, 2016, https://doi.org/10.1128/mBio.01776-15), and the processing times and resource costs from the laboratory staff time viewpoint were used to compare periprosthetic tissues culture processes using conventional techniques with culture in blood culture bottles. Sensitivity analysis was performed using various rates of positive cultures. Annualized labor savings were estimated based on salary costs from the U.S. Labor Bureau for Laboratory staff. The model demonstrated a 60.1% reduction in mean total staff time with the adoption of tissue inoculation into blood culture bottles compared to conventional techniques (mean ± standard deviation, 30.7 ± 27.6 versus 77.0 ± 35.3 h per month, respectively; P < 0.001). The estimated annualized labor cost savings of culture using blood culture bottles was $10,876.83 (±$337.16). Sensitivity analysis was performed using various rates of culture positivity (5 to 50%). Culture in blood culture bottles was cost-effective, based on the estimated labor cost savings of $2,132.71 for each percent increase in test accuracy. In conclusion, culture of periprosthetic tissue in blood culture bottles is not only more accurate than but is also cost-saving compared to conventional culture methods. Copyright © 2017 American Society for Microbiology.

Transoceanic drift and the domestication of African bottle gourds in the Americas.

PubMed

Kistler, Logan; Montenegro, Alvaro; Smith, Bruce D; Gifford, John A; Green, Richard E; Newsom, Lee A; Shapiro, Beth

2014-02-25

Bottle gourd (Lagenaria siceraria) was one of the first domesticated plants, and the only one with a global distribution during pre-Columbian times. Although native to Africa, bottle gourd was in use by humans in east Asia, possibly as early as 11,000 y ago (BP) and in the Americas by 10,000 BP. Despite its utilitarian importance to diverse human populations, it remains unresolved how the bottle gourd came to be so widely distributed, and in particular how and when it arrived in the New World. A previous study using ancient DNA concluded that Paleoindians transported already domesticated gourds to the Americas from Asia when colonizing the New World [Erickson et al. (2005) Proc Natl Acad Sci USA 102(51):18315-18320]. However, this scenario requires the propagation of tropical-adapted bottle gourds across the Arctic. Here, we isolate 86,000 base pairs of plastid DNA from a geographically broad sample of archaeological and living bottle gourds. In contrast to the earlier results, we find that all pre-Columbian bottle gourds are most closely related to African gourds, not Asian gourds. Ocean-current drift modeling shows that wild African gourds could have simply floated across the Atlantic during the Late Pleistocene. Once they arrived in the New World, naturalized gourd populations likely became established in the Neotropics via dispersal by megafaunal mammals. These wild populations were domesticated in several distinct New World locales, most likely near established centers of food crop domestication.

Transoceanic drift and the domestication of African bottle gourds in the Americas

PubMed Central

Kistler, Logan; Montenegro, Álvaro; Smith, Bruce D.; Gifford, John A.; Green, Richard E.; Newsom, Lee A.; Shapiro, Beth

2014-01-01

Bottle gourd (Lagenaria siceraria) was one of the first domesticated plants, and the only one with a global distribution during pre-Columbian times. Although native to Africa, bottle gourd was in use by humans in east Asia, possibly as early as 11,000 y ago (BP) and in the Americas by 10,000 BP. Despite its utilitarian importance to diverse human populations, it remains unresolved how the bottle gourd came to be so widely distributed, and in particular how and when it arrived in the New World. A previous study using ancient DNA concluded that Paleoindians transported already domesticated gourds to the Americas from Asia when colonizing the New World [Erickson et al. (2005) Proc Natl Acad Sci USA 102(51):18315–18320]. However, this scenario requires the propagation of tropical-adapted bottle gourds across the Arctic. Here, we isolate 86,000 base pairs of plastid DNA from a geographically broad sample of archaeological and living bottle gourds. In contrast to the earlier results, we find that all pre-Columbian bottle gourds are most closely related to African gourds, not Asian gourds. Ocean-current drift modeling shows that wild African gourds could have simply floated across the Atlantic during the Late Pleistocene. Once they arrived in the New World, naturalized gourd populations likely became established in the Neotropics via dispersal by megafaunal mammals. These wild populations were domesticated in several distinct New World locales, most likely near established centers of food crop domestication. PMID:24516122

Variations on the "Whoosh" Bottle Alcohol Explosion Demonstration Including Safety Notes.

ERIC Educational Resources Information Center

Fortman, John J.; Rush, Andrea C.; Stamper, Jennifer E.

1999-01-01

Presents several variations on a demonstration in which alcohol vapors are combusted in large small-necked bottles, causing a blue flame to shoot from the bottle's mouth. Describes variations with different pure alcohols, temperature, alcohol/water solution concentration, oxygen concentration, type of container, and the addition of salt for color.…

Message in a Bottle: What Shapes University Students' Understanding of Sustainability?

ERIC Educational Resources Information Center

Tuncer, Gaye; Sahin, Elvan

2016-01-01

Our research question concerned how life stories shape university students' understanding of the sustainable use of natural resources. We searched for an answer for this question by listening to the life stories of nine students from a public university in Turkey. The difference between this research and former work is that we were not concerned…

White HDPE bottles as source of serious contamination of water samples with Ba and Zn.

PubMed

Reimann, Clemens; Grimstvedt, Andreas; Frengstad, Bjørn; Finne, Tor Erik

2007-03-15

During a recent study of surface water quality factory new white high-density polyethylene (HDPE) bottles were used for collecting the water samples. According to the established field protocol of the Geological Survey of Norway the bottles were twice carefully rinsed with water in the field prior to sampling. Several blank samples using milli-Q (ELGA) water (>18.2 MOmega) were also prepared. On checking the analytical results the blanks returned values of Ag, Ba, Sr, V, Zn and Zr. For Ba and Zn the values (c. 300 microg/l and 95 microg/l) were about 10 times above the concentrations that can be expected in natural waters. A laboratory test of the bottles demonstrated that the bottles contaminate the samples with significant amounts of Ba and Zn and some Sr. Simple acid washing of the bottles prior to use did not solve the contamination problem for Ba and Zn. The results suggest that there may exist "clean" and "dirty" HDPE bottles depending on manufacturer/production process. When collecting water samples it is mandatory to check bottles regularly as a possible source of contamination.

The Unintended Consequences of Changes in Beverage Options and the Removal of Bottled Water on a University Campus

PubMed Central

Berman, Elizabeth R.

2015-01-01

Objectives. We investigated how the removal of bottled water along with a minimum healthy beverage requirement affected the purchasing behavior, healthiness of beverage choices, and consumption of calories and added sugars of university campus consumers. Methods. With shipment data as a proxy, we estimated bottled beverage consumption over 3 consecutive semesters: baseline (spring 2012), when a 30% healthy beverage ratio was enacted (fall 2012), and when bottled water was removed (spring 2013) at the University of Vermont. We assessed changes in number and type of beverages and per capita calories, total sugars, and added sugars shipped. Results. Per capita shipments of bottles, calories, sugars, and added sugars increased significantly when bottled water was removed. Shipments of healthy beverages declined significantly, whereas shipments of less healthy beverages increased significantly. As bottled water sales dropped to zero, sales of sugar-free beverages and sugar-sweetened beverages increased. Conclusions. The bottled water ban did not reduce the number of bottles entering the waste stream from the university campus, the ultimate goal of the ban. With the removal of bottled water, consumers increased their consumption of less healthy bottled beverages. PMID:25973813

27 CFR 19.204 - Alternation of distilled spirits plant and taxpaid wine bottling house premises.

Code of Federal Regulations, 2010 CFR

2010-04-01

... spirits plant and taxpaid wine bottling house premises. 19.204 Section 19.204 Alcohol, Tobacco Products... distilled spirits plant and taxpaid wine bottling house premises. (a) General. A proprietor of a distilled spirits plant operating a contiguous taxpaid wine bottling house desiring to alternate the use of each...

From Blogs to Bottle Caps

ERIC Educational Resources Information Center

Edinger, Ted

2012-01-01

There is a wonderful community of art educators connecting a once-isolated profession through blogging. Art educators around the world are sharing ideas and communicating with their peers through this amazing resource. In this article, the author describes the bottle cap mural at Tulip Grove Elementary School which was inspired by this exchange of…

FLUORIDE CONTENT OF COMMERCIALLY AVAILABLE BOTTLED DRINKING WATER IN BANGKOK, THAILAND.

PubMed

Rirattanapong, Praphasri; Rirattanapong, Opas

2016-09-01

The use of bottled drinking water may be a source of fluoride and could be a risk factor for fluorosis among infants and young children. The aim of this study was to evaluate the fluoride content of commercially available bottled drinking water in Bangkok, Thailand. Forty-five water samples (15 samples of plain water and 30 samples of mineral water) were purchased from several supermarkets in Bangkok, Thailand. Three bottles of each water sample were purchased, and the fluoride content of each sample was measured twice using a combination fluoride-ion selective electrode. The average reading for each sample was then calculated. Data were analyzed by descriptive statistics. Differences between mineral and plain water samples were determined by Student’s t-test. The mean (±SD) fluoride content for all the water samples was 0.17 (±0.17) mg F/l (range: 0.01-0.89 mg F/l). Six brands (13%) tested stated the fluoride content on the label. The actual fluoride content in each of their brands varied little from the label. Eight samples (18%) had a fluoride content >0.3 mg F/l and two samples (4%) had a fluoride content >0.6 mg F/l. The mean mineral water fluoride concentration was significantly higher than the mean fluoride concentration of plain water (p=0.001). We found commercially sold bottled drinking water in Bangkok, Thailand contained varying concentrations of fluoride; some with high concentrations of fluoride. Health professions need to be aware this varying fluoride content of bottled drinking water and educate the parents of infants and small children about this when prescribing fluoride supplements. Consideration should be made to have fluoride content put on the label of bottled water especially among brands with a content >0.3 mg F/l.

Stochastic Optimization in The Power Management of Bottled Water Production Planning

NASA Astrophysics Data System (ADS)

Antoro, Budi; Nababan, Esther; Mawengkang, Herman

2018-01-01

This paper review a model developed to minimize production costs on bottled water production planning through stochastic optimization. As we know, that planning a management means to achieve the goal that have been applied, since each management level in the organization need a planning activities. The built models is a two-stage stochastic models that aims to minimize the cost on production of bottled water by observing that during the production process, neither interfernce nor vice versa occurs. The models were develop to minimaze production cost, assuming the availability of packing raw materials used considered to meet for each kind of bottles. The minimum cost for each kind production of bottled water are expressed in the expectation of each production with a scenario probability. The probability of uncertainly is a representation of the number of productions and the timing of power supply interruption. This is to ensure that the number of interruption that occur does not exceed the limit of the contract agreement that has been made by the company with power suppliers.

Explicit Solvent Simulations of Friction between Brush Layers of Charged and Neutral Bottle-Brush Macromolecules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carrillo, Jan-Michael; Brown, W Michael; Dobrynin, Andrey

2012-01-01

We study friction between charged and neutral brush layers of bottle-brush macromolecules using molecular dynamics simulations. In our simulations the solvent molecules were treated explicitly. The deformation of the bottle-brush macromolecules under the shear were studied as a function of the substrate separation and shear stress. For charged bottle-brush layers we study effect of the added salt on the brush lubricating properties to elucidate factors responsible for energy dissipation in charged and neutral brush systems. Our simulations have shown that for both charged and neutral brush systems the main deformation mode of the bottle-brush macromolecule is associated with the backbonemore » deformation. This deformation mode manifests itself in the backbone deformation ratio, , and shear viscosity, , to be universal functions of the Weissenberg number W. The value of the friction coefficient, , and viscosity, , are larger for the charged bottle-brush coatings in comparison with those for neutral brushes at the same separation distance, D, between substrates. The additional energy dissipation generated by brush sliding in charged bottle-brush systems is due to electrostatic coupling between bottle-brush and counterion motion. This coupling weakens as salt concentration, cs, increases resulting in values of the viscosity, , and friction coefficient, , approaching corresponding values obtained for neutral brush systems.« less

Grip force and force sharing in two different manipulation tasks with bottles.

PubMed

Cepriá-Bernal, Javier; Pérez-González, Antonio; Mora, Marta C; Sancho-Bru, Joaquín L

2017-07-01

Grip force and force sharing during two activities of daily living were analysed experimentally in 10 right-handed subjects. Four different bottles, filled to two different levels, were manipulated for two tasks: transporting and pouring. Each test subject's hand was instrumented with eight thin wearable force sensors. The grip force and force sharing were significantly different for each bottle model. Increasing the filling level resulted in an increase in grip force, but the ratio of grip force to load force was higher for lighter loads. The task influenced the force sharing but not the mean grip force. The contributions of the thumb and ring finger were higher in the pouring task, whereas the contributions of the palm and the index finger were higher in the transport task. Mean force sharing among fingers was 30% for index, 29% for middle, 22% for ring and 19% for little finger. Practitioner Summary: We analysed grip force and force sharing in two manipulation tasks with bottles: transporting and pouring. The objective was to understand the effects of the bottle features, filling level and task on the contribution of different areas of the hand to the grip force. Force sharing was different for each task and the bottles features affected to both grip force and force sharing.

Fluoride concentration in community water and bottled drinking water: a dilemma today.

PubMed

Dhingra, S; Marya, C M; Jnaneswar, A; Kumar, H

2013-01-01

Because of the potential for contamination of municipal water supplies, people appear to be turning to alternative sources for their pure drinking water. The present study analyzed the fluoride concentration in community water and bottled drinking water sold in Faridabad city. A comparative evaluation of fluoride content in community water supply and bottled drinking water was done using ion-selective electrode method. The community water samples were collected from six different areas (i.e. north zone, south zone, east zone, west zone and central zone) in the city from public health water supply taps while bottled drinking water samples were randomly picked from grocery shops or supermarkets. The fluoride concentration in the community water supply in this study ranges from 0.11 to 0.26 mg/L with mean fluoride concentration of 0.17 mg/L. The mean concentration of fluoride in bottled drinking water was 0.06 mg/L. The differences observed between mean of two water samples was statistically significant. The results obtained from the present study clearly state that the fluoride concentration was insufficient in community water supply from all the areas and also was deficient in bottled drinking water sold in Faridabad city. So, Alternative sources of fluorides should be supplemented for optimal dental benefits from the use of fluoride.

Panel Board From Coconut Fibre And Pet Bottle

NASA Astrophysics Data System (ADS)

Ngadiman, Norhayati; Kaamin, Masiri; Abd. Kadir, Aslila; Sahat, Suhaila; Zaini, Aziza; Raihana Nor Zentan, Siti; Ain Ahmad, Nur; Amran, Wan Haizatul Aisyhah Wan

2018-03-01

The rate of global deforestation and its impact on the environment has led particle board manufacture to search for alternative feedstock, especially in countries where wood is less available compared to other cellulosic natural product. Based on the properties of coconut fibre and PET bottle, these two materials can be recycle as raw material for manufacture of panel board. As for this study, the coconut fibre were used as the filler and PET bottle as outer lining of the panel board. Two types of coconut fibre were used which are grinding and un-grinding coconut fibre. At first, the coconut fibre are undergoes softening, grinding, drying and sieving process, while PET bottle was cleaning, shredding, sieving before compacted using hydraulic hot press machine. There are four types of testing that been carried out which are swelling, water absorption, Modulus of Elasticity (MOE) and Modulus of Rupture (MOR). The result show the conventional board has the highest value for MOE test, so it's indicate that the conventional board is less strength from the coconut fibre board. As for water absorption test, the average water absorption of coconut fibre based panel board is less than conventional board. Overall, the coconut fibre board is better than conventional panel board because coconut fibre board are less swelling, has low water absorption, high modulus of rupture and low modulus of elasticity. Based on the finding, this coconut fibre panel board has potential as a stronger and long-lasting panel board than the conventional board in the market. Other than that, the panel also have their own aesthetic value since the recycled plastic bottle used as outer lining is colourful and giving aesthetic value.

5-(Perylen-3-yl)Ethynyl-arabino-Uridine (aUY11), an Arabino-Based Rigid Amphipathic Fusion Inhibitor, Targets Virion Envelope Lipids To Inhibit Fusion of Influenza Virus, Hepatitis C Virus, and Other Enveloped Viruses

PubMed Central

Colpitts, Che C.; Ustinov, Alexey V.; Epand, Raquel F.; Epand, Richard M.; Korshun, Vladimir A.

2013-01-01

Entry of enveloped viruses requires fusion of viral and cellular membranes. Fusion requires the formation of an intermediate stalk structure, in which only the outer leaflets are fused. The stalk structure, in turn, requires the lipid bilayer of the envelope to bend into negative curvature. This process is inhibited by enrichment in the outer leaflet of lipids with larger polar headgroups, which favor positive curvature. Accordingly, phospholipids with such shape inhibit viral fusion. We previously identified a compound, 5-(perylen-3-yl)ethynyl-2′-deoxy-uridine (dUY11), with overall shape and amphipathicity similar to those of these phospholipids. dUY11 inhibited the formation of the negative curvature necessary for stalk formation and the fusion of a model enveloped virus, vesicular stomatitis virus (VSV). We proposed that dUY11 acted by biophysical mechanisms as a result of its shape and amphipathicity. To test this model, we have now characterized the mechanisms against influenza virus and HCV of 5-(perylen-3-yl)ethynyl-arabino-uridine (aUY11), which has shape and amphipathicity similar to those of dUY11 but contains an arabino-nucleoside. aUY11 interacted with envelope lipids to inhibit the infectivity of influenza virus, hepatitis C virus (HCV), herpes simplex virus 1 and 2 (HSV-1/2), and other enveloped viruses. It specifically inhibited the fusion of influenza virus, HCV, VSV, and even protein-free liposomes to cells. Furthermore, aUY11 inhibited the formation of negative curvature in model lipid bilayers. In summary, the arabino-derived aUY11 and the deoxy-derived dUY11 act by the same antiviral mechanisms against several enveloped but otherwise unrelated viruses. Therefore, chemically unrelated compounds of appropriate shape and amphipathicity target virion envelope lipids to inhibit formation of the negative curvature required for fusion, inhibiting infectivity by biophysical, not biochemical, mechanisms. PMID:23283943

The bacteriological quality of different brands of bottled water available to consumers in Ile-Ife, south-western Nigeria.

PubMed

Igbeneghu, Oluwatoyin A; Lamikanra, Adebayo

2014-11-28

The upsurge in the demand for bottled water has prompted the interest of many manufacturers in the production of bottled water and very many water bottling companies are therefore involved in its production. These range from large scale multinational companies to medium scale business enterprises, institutional and government business investment companies as well as small scale entrepreneurs. There is however little information on the comparative quality of bottled water brands produced by different classes of water bottling companies in Nigeria. This study was undertaken to determine the bacteriological quality of brands of bottled water available to consumers in Ile-Ife. Forty-three samples of bottled water comprising of three batches each of thirteen bottled water brands and two batches of two brands were purchased and analyzed for total bacterial count, presence of coliform and the presence of other bacterial indicators of drinking water quality. Only 67.4% of the water samples representing the products of 10 companies or 66.7% of the brands had heterotrophic counts within the acceptable limits. Coliforms present in 100 ml of water were detected in 26.7% of the bottled water brands. Other indicator organisms detected included Staphylococci isolated from 27.9% of the samples (33.3% of the brands) and specifically Staphylococcus aureus found in four brands constituting 14% of the samples. Pseudomonas strains were consistently detected in consecutive batches of three brands of the water samples. Bottled water samples produced by the large scale multinational producers were of acceptable bacteriological quality unlike those produced by most small companies. There is need for a greater control of water bottling processes carried out by commercial bottled water producers in Nigeria.

Safety of Bottled Water Beverages Including Flavored Water and Nutrient-Added Water Beverages

MedlinePlus

... verifies that the plant's product water and operational water supply are obtained from an approved source; inspects washing and sanitizing procedures; inspects bottling operations; and determines whether ... water and product water for contaminants. Americans like bottled ...

Treatment techniques for the recycling of bottle washing water in the soft drinks industry.

PubMed

Ramirez Camperos, E; Mijaylova Nacheva, P; Diaz Tapia, E

2004-01-01

The soft drink production is an important sector in the manufacturing industry of Mexico. Water is the main source in the production of soft drinks. Wastewater from bottle washing is almost 50% of the total wastewater generated by this industry. In order to reduce the consumption of water, the water of the last bottle rinse can be reused in to the bottle pre-rinse and pre-washing cycles. This work presents the characterization of the final bottle washing rinse discharge and the treatability study for the most appropriate treatment system for recycling. Average characteristics of the final bottle wash rinse were as follows: Turbidity 40.46 NTU, COD 47.7 mg/L, TSS 56 mg/L, TS 693.6 mg/L, electrical conductivity 1,194 microS/cm. The results of the treatability tests showed that the final rinse water can be used in the pre-rinse and pre-washing after removing the totality of the suspended solids, 80% of the COD and 75% of the dissolved solids. This can be done using the following treatment systems: filtration-adsorption-reverse osmosis, or filtration-adsorption-ion exchange. The installation of these treatment techniques in the soft drink industry would decrease bottle washing water consumption by 50%.

Migration of bisphenol A from polycarbonate baby and water bottles into water under severe conditions.

PubMed

Cao, Xu-Liang; Corriveau, Jeannette

2008-08-13

The isotope dilution headspace solid-phase microextraction and gas chromatography-mass spectrometry method for bisphenol A (BPA) developed previously was used successfully in a BPA migration study at 70 degrees C of polycarbonate baby and reusable water bottles recently sold in Canada by using the whole bottles instead of pieces cut from the bottles. Migration of BPA from the PC bottles heated at 70 degrees C was found to increase over the time in the quadratic equations. Migration levels of BPA in water varied from 228 to 521 microg L (-1) or from 0.26 to 0.90 microg cm (-2) after being heated at 70 degrees C for 6 days. The average migration rates of BPA from the PC bottles into water at 70 degrees C ranged from 1.84 to 4.83 ng cm (-2) h (-1).

Concentrations of selected trace elements in mineral and spring bottled waters on the Serbian market.

PubMed

Ristić, M; Popović, I; Pocajt, V; Antanasijević, D; Perić-Grujić, A

2011-01-01

Eight selected trace elements, which are generally included in regulations, were analyzed in 23 types of bottled waters. Ten mineral and seven spring bottled waters were from the Serbian market and six mineral bottled waters were obtained in different EU countries. For the purpose of comparison, selected tap waters were also analyzed. Inductively coupled plasma mass spectrometry (ICP-MS) was used for the analysis of trace elements (arsenic, cadmium, copper, manganese, nickel, lead and antimony). Results were compared with the Serbian regulations for bottled water, EU regulations and guideline values set by the World Health Organization for drinking water. With few exceptions, the trace element levels of most bottled waters were below the guideline values. However, a higher content of antimony was observed in waters from polyethylene terephthalate (PET) containers, indicating a potential leaching of this element from the plastic packaging.

Evaluation of the effectiveness of an intravenous line and fluid bottle fixation design.

PubMed

Chiou, Piao-Yi; Chien, Chih-Yin; Shiu, Ting-Ru; Lin, Pei-Jiun; Lin, Wan-Yu; Jiang, Yi-Rung

2015-01-01

It's important to improve the stability of intravenous (IV) lines and bottles during patient activity and nursing care. We developed an intravenous line and fluid bottle fixation design (ILFBFD) which includes a bottle retaining clip and line fixation kit. We randomly assigned 60 participants each to the experimental and control groups. Participants were asked to push an IV stand without and with ILFBFD 11 meters on uneven pavement and a sloping floor. The distance the IV bottle moved was recorded. Self-administered questionnaires were used to collect the opinions of the participants. Use of ILFBFD, resulted in less movement in the anteroposterior and left/right directions (differences of 46.98 cm2, t= 12.80, p < 0.000 and 39.24 cm2, t= 8.01, p< 0.000, respectively) compared with not using ILFBFD. The average scores for bottle movement when participants walked on a flat floor, uneven pavement and sloping floor, IV line tangling and dropping, and organization of Liv lines were significantly better in those using than not using ILFBFD. The results can be used in clinical practice to reduce knotting of IV lines, and to enhance the safety and quality of patient care.

Assessment of Bisphenol A Released from Reusable Plastic, Aluminium and Stainless Steel Water Bottles

PubMed Central

Cooper, James E.; Kendig, Eric L.; Belcher, Scott M.

2011-01-01

Bisphenol A(BPA) is a ubiquitous high volume industrial chemical that is an estrogen and an environmental endocrine disrupting chemical. Bisphenol A is used extensively in the production of consumer goods, polycarbonate plastics, epoxy resins, coating used to line metallic food and beverage cans, and other products.There is great concern regarding the possible harmful effects from exposures that result from BPAleaching into foods and beverages from packaging or storage containers. The objective of this study was to independently assesswhether BPA contamination of water was occurring from different types of reusable drinking bottlesmarketed as alternatives to BPA-containing polycarbonate plastics. Using a sensitive and quantitative BPA-specific competitive enzyme-linked immunosorbent assaywe evaluated whether BPA migrated into water stored inpolycarbonateor copolyester plastic bottles, and different lined or unlined metallic reusable water bottles. At room temperature the concentration of BPA migrating from polycarbonate bottles ranged from 0.2–0.3 mg/L. Under identical conditions BPA migration from aluminium bottles lined with epoxy-based resins was variable depending on manufacturer ranging from 0.08 to 1.9 mg/L.Boiling water significantly increased migration of BPA from the epoxy lined bottles. No detectable BPA contamination was observed in water stored in bottles made from Tritan™ copolyester plastic, uncoated stainless steel, or aluminium lined with EcoCare™. The results from this study demonstrate that when used according to manufactures’ recommendations reusable water bottles constructed from “BPA-free” alternative materials are suitable for consumption of beverages free of BPA contamination. PMID:21741673

Effect of production phase on bottle-fermented sparkling wine quality.

PubMed

Kemp, Belinda; Alexandre, Hervé; Robillard, Bertrand; Marchal, Richard

2015-01-14

This review analyzes bottle-fermented sparkling wine research at each stage of production by evaluating existing knowledge to identify areas that require future investigation. With the growing importance of enological investigation being focused on the needs of the wine production industry, this review examines current research at each stage of bottle-fermented sparkling wine production. Production phases analyzed in this review include pressing, juice adjustments, malolactic fermentation (MLF), stabilization, clarification, tirage, lees aging, disgorging, and dosage. The aim of this review is to identify enological factors that affect bottle-fermented sparkling wine quality, predominantly aroma, flavor, and foaming quality. Future research topics identified include regional specific varieties, plant-based products from vines, grapes, and yeast that can be used in sparkling wine production, gushing at disgorging, and methods to increase the rate of yeast autolysis. An internationally accepted sensory analysis method specifically designed for sparkling wine is required.

Perceived impact of smaller compared with larger-sized bottles of sugar-sweetened beverages on consumption: A qualitative analysis.

PubMed

Mantzari, Eleni; Hollands, Gareth J; Pechey, Rachel; Jebb, Susan; Marteau, Theresa M

2018-01-01

Sugar-sweetened beverage (SSB) consumption increases obesity risk and is linked to adverse health consequences. Large packages increase food consumption, but most evidence comes from studies comparing larger with standard packages, resulting in uncertainty regarding the impact of smaller packages. There is also little research on beverages. This qualitative study explores the experiences of consuming cola from smaller compared with larger bottles, to inform intervention strategies. Sixteen households in Cambridge, England, participating in a feasibility study assessing the impact of bottle size on in-home SSB consumption, received a set amount of cola each week for four weeks in one of four bottle sizes: 1500 ml, 1000 ml, 500 ml, or 250 ml, in random order. At the study end, household representatives were interviewed about their experiences of using each bottle, including perceptions of i) consumption level; ii) consumption-related behaviours; and iii) factors affecting consumption. Interviews were semi-structured and data analysed using the Framework approach. The present analysis focuses specifically on experiences relating to use of the smaller bottles. The smallest bottles were described as increasing drinking occasion frequency and encouraging consumption of numerous bottles in succession. Factors described as facilitating their consumption were: i) convenience and portability; ii) greater numbers of bottles available, which hindered consumption monitoring and control; iii) perceived insufficient quantity per bottle; and iv) positive attitudes. In a minority of cases the smallest bottles were perceived to have reduced consumption, but this was related to practical issues with the bottles that resulted in dislike. The perception of greater consumption and qualitative reports of drinking habits associated with the smallest bottles raise the possibility that the 'portion size effect' has a lower threshold, beyond which smaller portions and packages may

Alternative Fuels Data Center: Coca-Cola Bottling Co. Brings Hybrids to New

Science.gov Websites

as a great example of a viable clean transportation option for similar fleets. " Rebecca Otte commitment to a more sustainable community and serves as a great example of a viable clean transportation , individual bottling companies now operate these vehicles. For example, Coca-Cola Bottling Company United

Quality comparison of tap water vs. bottled water in the industrial city of Yanbu (Saudi Arabia).

PubMed

Ahmad, Maqbool; Bajahlan, Ahmad S

2009-12-01

This study was conducted to compare the quality of bottled water with potabilized desalinated tap water. Fourteen brands of local and imported bottled water samples were collected from the local market and analyzed for physicochemical parameters in the Royal Commission Environmental Laboratory. Results were compared with 5-year continuous monitoring data of tap water from different locations in Madinat Yanbu Al-Sinaiyah (MYAS) including storage tanks of desalination plant. Results show that there was no significant difference in the quality of tap water and bottled water. Bacteriological test was never found positive in the 5-year data in tap water. Similarly, physicochemical analysis shows the persistent quality of tap water. Based on hardness analysis, bottled and tap water are categorized as soft water. Trihalomethanes (THMs) study also indicates that traces of disinfection by products (DBPs) are present in both tap and bottled water and are much less than the World Health Organization and Environmental Protection Agency maximum permissible limits. It is also important to note that the tap water distribution network in MAYS is a high-pressure recirculation network and there is no chance to grow bacteria in stagnant water in pipe lines or houses. Recently, the Royal Commission has replaced the whole drinking water network, which was made of asbestos-cemented pipes with glass-reinforced plastic (GRP) pipes, to avoid any asbestos contaminations. Based on these results, it is concluded that drinking water distributed in the city is of very good and persistent quality, comparable with bottled water. Continuous monitoring also guarantees the safe drinking water to the community. Hence, it is the responsibility of the Royal Commission to encourage the peoples in the city to drink tap water as it is as good as bottled water even better than some of the brands and is monitored regularly. It is also much cheaper compared to bottled water and is available round the clock

Bottle milk feeding and its association with food group consumption, growth and socio-demographic characteristics in Chinese young children.

PubMed

Yeung, Suey; Chan, Ruth; Li, Liz; Leung, Shirley; Woo, Jean

2017-07-01

It is recommended that infants from the age of 12 months should be weaned from bottles. However, an overwhelming proportion of young children were still using bottle after the recommended age of bottle-weaning. This cross-sectional study examined the association between utensils for milk drinking and food group consumption, growth and socio-demographic characteristics among young children. Data from the Survey of Infant and Young Child Feeding in Hong Kong were analyzed for 649 children aged 18-48 months old. Dietary outcomes were obtained via 3-day dietary records, while utensils for milk drinking and socio-demographic characteristics were collected from a self-developed questionnaire. Length/height and weight of the children were measured by the nurses. Results showed that daily consumption of formula milk was significantly greater among bottle users or bottle plus cup users than non-bottle users (p < 0.05). Exclusive bottle users had significantly lower intakes of meat and meat alternatives than bottle plus cup users for the 18 to 24-month group (p = 0.001) and lower intakes of fruits than non-bottle users in the 48-month group (p = 0.015). BMI z-score was significantly higher for exclusive bottle users than non-bottle users, even after adjusting for socio-economic factors and child's age (p = 0.006). The results showed that the milk drinking utensil was associated with the amount of formula milk and food group consumption as well as BMI z-score. There is a need to actively discourage prolonged bottle use in order to help young children develop good dietary habits. © 2016 John Wiley & Sons Ltd. © 2016 John Wiley & Sons Ltd.

10 CFR 431.292 - Definitions concerning refrigerated bottled or canned beverage vending machines.

Code of Federal Regulations, 2010 CFR

2010-01-01

... beverage vending machines. 431.292 Section 431.292 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY... Vending Machines § 431.292 Definitions concerning refrigerated bottled or canned beverage vending machines. Basic model means, with respect to refrigerated bottled or canned beverage vending machines, all units...

Indoor cultivation and cultural characteristics of Wolfiporia cocos sclerotia using mushroom culture bottles.

PubMed

Kubo, Toshiyuki; Terabayashi, Susumu; Takeda, Shuichi; Sasaki, Hiroshi; Aburada, Masaki; Miyamoto, Ken-ichi

2006-06-01

We newly developed an indoor cultivation technique for Wolfiporia cocos (Wolf) Ryvarden et Gilbertson (Syn. Poria cocos Wolf), not with soil, but using mushroom culture bottles with pine logs, and clarified some cultural characteristics of sclerotia in the laboratory. To determine the optimum conditions for sclerotia growth, the weight of sclerotia and concentration of CO2 in three different air filters; cloth, paper and urethane resin, and closed bottles were tested. When the cloth air filter was used, the growth rate was the fastest and the yield was maximal. These results suggested that the aeration was an important environmental factor for cultivation. To clarify the characteristics of culture in the cloth air filtered and closed bottles, the weight of sclerotia, the compositions of pine logs and the contents of pachymic acid and dehydropachymic acid were examined during 24 weeks. The growth of scleroia and the wood decaying efficiency in the cloth air filtered bottles were better than those in the closed bottles. Also, it was found that W. cocos was a brown rot fungus due to the alkaline solubility of pine logs in the wood decay process. In addition, the contents of pachymic acid and dehydropachymic acid and the TLC pattern between the cultivated and commercial sclerotia did not differ remarkably.

Optical vault: a reconfigurable bottle beam based on conical refraction of light.

PubMed

Turpin, A; Shvedov, V; Hnatovsky, C; Loiko, Yu V; Mompart, J; Krolikowski, W

2013-11-04

We employ conical refraction of light in a biaxial crystal to create an optical bottle for photophoretic trapping and manipulation of particles in gaseous media. We show that by only varying the polarization state of the input light beam the optical bottle can be opened and closed in order to load and unload particles in a highly controllable manner.

21 CFR 189.301 - Tin-coated lead foil capsules for wine bottles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Tin-coated lead foil capsules for wine bottles... Substances Prohibited From Indirect Addition to Human Food Through Food-Contact Surfaces § 189.301 Tin-coated lead foil capsules for wine bottles. (a) Tin-coated lead foil is composed of a lead foil coated on one...

21 CFR 189.301 - Tin-coated lead foil capsules for wine bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Tin-coated lead foil capsules for wine bottles. 189... Substances Prohibited From Indirect Addition to Human Food Through Food-Contact Surfaces § 189.301 Tin-coated lead foil capsules for wine bottles. (a) Tin-coated lead foil is composed of a lead foil coated on one...

21 CFR 189.301 - Tin-coated lead foil capsules for wine bottles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Tin-coated lead foil capsules for wine bottles... Substances Prohibited From Indirect Addition to Human Food Through Food-Contact Surfaces § 189.301 Tin-coated lead foil capsules for wine bottles. (a) Tin-coated lead foil is composed of a lead foil coated on one...

21 CFR 189.301 - Tin-coated lead foil capsules for wine bottles.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Tin-coated lead foil capsules for wine bottles... Substances Prohibited From Indirect Addition to Human Food Through Food-Contact Surfaces § 189.301 Tin-coated lead foil capsules for wine bottles. (a) Tin-coated lead foil is composed of a lead foil coated on one...

Effect of Fungal Competition on Decay Rates in Bicultured Soil Bottle Assays

Treesearch

Grant T. Kirker; Amy Blodgett; Patricia K. Lebow; Carol A. Clausen

2016-01-01

For decades, wood scientists and preservative formulators have employed the monocultured soil bottle assay to test efficacy of wood treatment in the laboratory as a rapid predictor of field performance. This study examines the effects of bicultured soil bottle assays on the decay by common wood decay fungi. Mycelial interactions were noted in early stages of...

Does bottle type and acid-washing influence trace element analyses by ICP-MS on water samples? A test covering 62 elements and four bottle types: high density polyethene (HDPE), polypropene (PP), fluorinated ethene propene copolymer (FEP) and perfluoroalkoxy polymer (PFA).

PubMed

Reimann, C; Siewers, U; Skarphagen, H; Banks, D

1999-10-01

Groundwater samples from 15 boreholes in crystalline bedrock aquifers in South Norway (Oslo area) have been collected in parallel in five different clear plastic bottle types (high density polyethene [HDPE], polypropene [PP, two manufacturers], fluorinated ethene propene copolymer [FEP] and perfluoroalkoxy polymer [PFA]. In the cases of polyethene and polypropene, parallel samples have been collected in factory-new (unwashed) bottles and acid-washed factory-new bottles. Samples have been analysed by ICP-MS techniques for a wide range of inorganic elements down to the ppt (ng/l) range. It was found that acid-washing of factory-new flasks had no clear systematic beneficial effect on analytical result. On the contrary, for the PP-bottles concentrations of Pb and Sn were clearly elevated in the acid-washed bottles. Likewise, for the vast majority of elements, bottle type was of no importance for analytical result. For six elements (Al, Cr, Hf, Hg, Pb and Sn) some systematic differences for one or more bottle types could be tentatively discerned, but in no case was the discrepancy of major cause for concern. The most pronounced effect was for Cr, with clearly elevated concentrations returned from the samples collected in HDPE bottles, regardless of acid-washing or not. For the above six elements, FEP or PFA bottles seemed to be marginally preferable to PP and HDPE. In general, cheap HDPE, factory new, unwashed flasks are suitable for sampling waters for ICP-MS ultra-trace analysis of the elements tested.

An effective purification method using large bottles for human pancreatic islet isolation

PubMed Central

Shimoda, Masayuki; Itoh, Takeshi; Iwahashi, Shuichi; Takita, Morihito; Sugimoto, Koji; Kanak, Mazhar A.; Chujo, Daisuke; Naziruddin, Bashoo; Levy, Marlon F.; Grayburn, Paul A.; Matsumoto, Shinichi

2012-01-01

The purification process is one of the most difficult procedures in pancreatic islet isolation. It was demonstrated that the standard purification method using a COBE 2991 cell processor with Ficoll density gradient solution harmed islets mechanically by high shear force. We reported that purification using large bottles with a lower viscosity gradient solution could improve the efficacy of porcine islet purification. In this study, we examined whether the new bottle purification method could improve the purification of human islets. Nine human pancreata from brain-dead donors were used. After pancreas digestion, the digested tissue was divided into three groups. Each group was purified by continuous density gradient using ET-Kyoto and iodixanol gradient solution with either the standard COBE method (COBE group) or the top loading (top group) or bottom loading (bottom group) bottle purification methods. Islet yield, purity, recovery rate after purification, and in vitro and in vivo viability were compared. Islet yield per pancreas weight (IE/g) and the recovery rate in the top group were significantly higher than in the COBE and bottom groups. Furthermore, the average size of purified islets in the top group was significantly larger than in the COBE group, which indicated that the bottle method could reduce the shear force to the islets. In vivo viability was also significantly higher in the top group compared with the COBE group. In conclusion, the top-loading bottle method could improve the quality and quantity of human islets after purification. PMID:23221740

Terminal acidic shock inhibits sour beer bottle conditioning by Saccharomyces cerevisiae.

PubMed

Rogers, Cody M; Veatch, Devon; Covey, Adam; Staton, Caleb; Bochman, Matthew L

2016-08-01

During beer fermentation, the brewer's yeast Saccharomyces cerevisiae experiences a variety of shifting growth conditions, culminating in a low-oxygen, low-nutrient, high-ethanol, acidic environment. In beers that are bottle conditioned (i.e., carbonated in the bottle by supplying yeast with a small amount of sugar to metabolize into CO2), the S. cerevisiae cells must overcome these stressors to perform the ultimate act in beer production. However, medium shock caused by any of these variables can slow, stall, or even kill the yeast, resulting in production delays and economic losses. Here, we describe a medium shock caused by high lactic acid levels in an American sour beer, which we refer to as "terminal acidic shock". Yeast exposed to this shock failed to bottle condition the beer, though they remained viable. The effects of low pH/high [lactic acid] conditions on the growth of six different brewing strains of S. cerevisiae were characterized, and we developed a method to adapt the yeast to growth in acidic beer, enabling proper bottle conditioning. Our findings will aid in the production of sour-style beers, a trending category in the American craft beer scene. Copyright © 2016 Elsevier Ltd. All rights reserved.

What's Wrong with the Tap? Examining Perceptions of Tap Water and Bottled Water at Purdue University

NASA Astrophysics Data System (ADS)

Saylor, Amber; Prokopy, Linda Stalker; Amberg, Shannon

2011-09-01

The environmental impacts of bottled water prompted us to explore drinking water choices at Purdue University, located in West Lafayette, IN. A random sample of 2,045 Purdue University students, staff, and faculty was invited to participate in an online survey. The survey assessed current behaviors as well as perceived barriers and benefits to drinking tap water versus bottled water. 677 surveys were completed for a response rate of 33.1%. We then conducted qualitative interviews with a purposive sample of university undergraduates ( n = 21) to obtain contextual insights into the survey results and the beliefs of individuals with a variety of drinking water preferences. This study revealed that women drink disproportionately more bottled water then men while undergraduate students drink more than graduate students, staff and faculty. The study also uncovered a widespread belief that recycling eliminates the environmental impacts of bottled water. Important barriers to drinking tap water at Purdue include: perceived risks from tap water and the perceived safety of bottled water, preferring the taste of bottled water, and the convenience of drinking bottled water. The qualitative interviews revealed that drinking water choices can be influenced by several factors—especially whether individuals trust tap water to be clean—but involve varying levels of complexity. The implications of these results for social marketing strategies to promote tap water are discussed.

What's wrong with the tap? Examining perceptions of tap water and bottled water at Purdue University.

PubMed

Saylor, Amber; Prokopy, Linda Stalker; Amberg, Shannon

2011-09-01

The environmental impacts of bottled water prompted us to explore drinking water choices at Purdue University, located in West Lafayette, IN. A random sample of 2,045 Purdue University students, staff, and faculty was invited to participate in an online survey. The survey assessed current behaviors as well as perceived barriers and benefits to drinking tap water versus bottled water. 677 surveys were completed for a response rate of 33.1%. We then conducted qualitative interviews with a purposive sample of university undergraduates (n = 21) to obtain contextual insights into the survey results and the beliefs of individuals with a variety of drinking water preferences. This study revealed that women drink disproportionately more bottled water then men while undergraduate students drink more than graduate students, staff and faculty. The study also uncovered a widespread belief that recycling eliminates the environmental impacts of bottled water. Important barriers to drinking tap water at Purdue include: perceived risks from tap water and the perceived safety of bottled water, preferring the taste of bottled water, and the convenience of drinking bottled water. The qualitative interviews revealed that drinking water choices can be influenced by several factors-especially whether individuals trust tap water to be clean-but involve varying levels of complexity. The implications of these results for social marketing strategies to promote tap water are discussed.

10 CFR 431.292 - Definitions concerning refrigerated bottled or canned beverage vending machines.

Code of Federal Regulations, 2011 CFR

2011-01-01

... cooled, and is not a combination vending machine. Class B means any refrigerated bottled or canned beverage vending machine not considered to be Class A, and is not a combination vending machine. Combination vending machine means a refrigerated bottled or canned beverage vending machine that also has non...

Multi-Generational Drinking of Bottled Low Mineral Water Impairs Bone Quality in Female Rats

PubMed Central

Zeng, Hui; Wang, Lingqiao; Wang, Dahua; Luo, Jiaohua; Zhang, Liang; Huang, Yujing; Chen, Ji-an; Shu, Weiqun

2015-01-01

Background Because of reproductions and hormone changes, females are more sensitive to bone mineral loss during their lifetime. Bottled water has become more popular in recent years, and a large number of products are low mineral water. However, research on the effects of drinking bottled low mineral water on bone health is sparse. Objective To elucidate the skeletal effects of multi-generational bottled water drinking in female rats. Methods Rats continuously drank tap water (TW), bottled natural water (bNW), bottled mineralized water (bMW), or bottled purified water (bPW) for three generations. Results The maximum deflection, elastic deflection, and ultimate strain of the femoral diaphysis in the bNW, bMW, and bPW groups and the fracture strain in the bNW and bMW groups were significantly decreased. The tibiae calcium levels in both the bNW and bPW groups were significantly lower than that in the TW group. The tibiae and teeth magnesium levels in both the bNW and bPW groups were significantly lower than those in the TW group. The collagen turnover markers PICP (in both bNW and bPW groups) were significantly lower than that in the TW group. In all three low mineral water groups, the 1,25-dihydroxy-vitamin D levels were significantly lower than those in the TW group. Conclusion Long-term drinking of low mineral water may disturb bone metabolism and biochemical properties and therefore weaken biomechanical bone properties in females. Drinking tap water, which contains adequate minerals, was found to be better for bone health. To our knowledge, this is the first report on drinking bottled low mineral water and female bone quality on three generation model. PMID:25803851

21 CFR 165.110 - Bottled water.

Code of Federal Regulations, 2010 CFR

2010-04-01

... bottles or other containers with no added ingredients except that it may optionally contain safe and... Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030, or go to... availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register...

21 CFR 189.301 - Tin-coated lead foil capsules for wine bottles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Tin-coated lead foil capsules for wine bottles... Addition to Human Food Through Food-Contact Surfaces § 189.301 Tin-coated lead foil capsules for wine bottles. (a) Tin-coated lead foil is composed of a lead foil coated on one or both sides with a thin layer...

Cavity-enhanced optical bottle beam as a mechanical amplifier

NASA Astrophysics Data System (ADS)

Freegarde, Tim; Dholakia, Kishan

2002-07-01

We analyze the resonant cavity enhancement of a hollow ``optical bottle beam'' for the dipole-force trapping of dark-field-seeking species. We first improve upon the basic bottle beam by adding further Laguerre-Gaussian components to deepen the confining potential. Each of these components itself corresponds to a superposition of transverse cavity modes, which are then enhanced simultaneously in a confocal cavity to produce a deep optical trap needing only a modest incident power. The response of the trapping field to displacement of the cavity mirrors offers an unusual form of mechanical amplifier in which the Gouy phase shift produces an optical Vernier scale between the Laguerre-Gaussian beam components.

On the use of drift bottle and seabed drifter data in coastal management

NASA Technical Reports Server (NTRS)

Welch, C. S.; Norcross, J. J.

1973-01-01

The use of drift bottle and seabed drifter information for use in coastal management is discussed. The drift bottle/seabed drifter portion of VIMS project MACONS (Mid Atlantic Continental Shelf) is described as an example of how a comprehensive survey using drift bottles and seabed drifters provides data useful for coastal management. The data from MACONS are analyzed to answer specific questions of interest to several different coastal managers: a manager siting a deep oil port, one siting a sewage outfall, a manager responsible for setting up emergency beach protection procedures before an accident occurs, and a manager responsible for the environmental quality of a particular small section of coastline.

The Dynamic Density Bottle: A Make-and-Take, Guided Inquiry Activity on Density

ERIC Educational Resources Information Center

Kuntzleman, Thomas S.

2015-01-01

An activity is described wherein students observe dynamic floating and sinking behavior of plastic pieces in various liquids. The liquids and solids are all contained within a plastic bottle; the entire assembly is called a "density bottle". After completing a series of experiments that guides students to think about the relative…

Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans

PubMed Central

Grifoni, Alba; Pham, John; Sidney, John; O'Rourke, Patrick H.; Paul, Sinu; Peters, Bjoern; Martini, Sheridan R.; de Silva, Aruna D.; Ricciardi, Michael J.; Silveira, Cassia G. T.; Maestri, Alvino; Costa, Priscilla R.; de-Oliveira-Pinto, Luzia Maria; de Azeredo, Elzinandes Leal; Damasco, Paulo Vieira; Phillips, Elizabeth; Mallal, Simon; de Silva, Aravinda M.; Collins, Matthew; Durbin, Anna; Diehl, Sean A.; Cerpas, Cristhiam; Balmaseda, Angel; Kuan, Guillermina; Coloma, Josefina; Harris, Eva; Crowe, James E.; Stone, Mars; Busch, Michael; Vivanco-Cid, Hector; Cox, Josephine; Graham, Barney S.; Ledgerwood, Julie E.; Turtle, Lance; Solomon, Tom; Kallas, Esper G.; Watkins, David I.; Weiskopf, Daniela

2017-01-01

ABSTRACT While progress has been made in characterizing humoral immunity to Zika virus (ZIKV) in humans, little is known regarding the corresponding T cell responses to ZIKV. Here, we investigate the kinetics and viral epitopes targeted by T cells responding to ZIKV and address the critical question of whether preexisting dengue virus (DENV) T cell immunity modulates these responses. We find that memory T cell responses elicited by prior infection with DENV or vaccination with tetravalent dengue attenuated vaccines (TDLAV) recognize ZIKV-derived peptides. This cross-reactivity is explained by the sequence similarity of the two viruses, as the ZIKV peptides recognized by DENV-elicited memory T cells are identical or highly conserved in DENV and ZIKV. DENV exposure prior to ZIKV infection also influences the timing and magnitude of the T cell response. ZIKV-reactive T cells in the acute phase of infection are detected earlier and in greater magnitude in DENV-immune patients. Conversely, the frequency of ZIKV-reactive T cells continues to rise in the convalescent phase in DENV-naive donors but declines in DENV-preexposed donors, compatible with more efficient control of ZIKV replication and/or clearance of ZIKV antigen. The quality of responses is also influenced by previous DENV exposure, and ZIKV-specific CD8 T cells from DENV-preexposed donors selectively upregulated granzyme B and PD1, unlike DENV-naive donors. Finally, we discovered that ZIKV structural proteins (E, prM, and C) are major targets of both the CD4 and CD8 T cell responses, whereas DENV T cell epitopes are found primarily in nonstructural proteins. IMPORTANCE The issue of potential ZIKV and DENV cross-reactivity and how preexisting DENV T cell immunity modulates Zika T cell responses is of great relevance, as the two viruses often cocirculate and Zika virus has been spreading in geographical regions where DENV is endemic or hyperendemic. Our data show that memory T cell responses elicited by prior

Assessing bottled water nitrate concentrations to evaluate total drinking water nitrate exposure and risk of birth defects.

PubMed

Weyer, Peter J; Brender, Jean D; Romitti, Paul A; Kantamneni, Jiji R; Crawford, David; Sharkey, Joseph R; Shinde, Mayura; Horel, Scott A; Vuong, Ann M; Langlois, Peter H

2014-12-01

Previous epidemiologic studies of maternal exposure to drinking water nitrate did not account for bottled water consumption. The objective of this National Birth Defects Prevention Study (NBDPS) (USA) analysis was to assess the impact of bottled water use on the relation between maternal exposure to drinking water nitrate and selected birth defects in infants born during 1997-2005. Prenatal residences of 1,410 mothers reporting exclusive bottled water use were geocoded and mapped; 326 bottled water samples were collected and analyzed using Environmental Protection Agency Method 300.0. Median bottled water nitrate concentrations were assigned by community; mothers' overall intake of nitrate in mg/day from drinking water was calculated. Odds ratios for neural tube defects, limb deficiencies, oral cleft defects, and heart defects were estimated using mixed-effects models for logistic regression. Odds ratios (95% CIs) for the highest exposure group in offspring of mothers reporting exclusive use of bottled water were: neural tube defects [1.42 (0.51, 3.99)], limb deficiencies [1.86 (0.51, 6.80)], oral clefts [1.43 (0.61, 3.31)], and heart defects [2.13, (0.87, 5.17)]. Bottled water nitrate had no appreciable impact on risk for birth defects in the NBDPS.

Effect of bottle height and aspiration rate on postocclusion surge in Infiniti and Millennium peristaltic phacoemulsification machines.

PubMed

Ward, Matthew S; Georgescu, Dan; Olson, Randall J

2008-08-01

To assess how flow and bottle height affect postocclusion surge in the Infiniti (Alcon, Inc.) and Millennium (Bausch & Lomb) peristaltic machines. John A. Moran Eye Center Clinical Laboratories, University of Utah, Salt Lake City, Utah. Postocclusion anterior chamber depth changes were measured in human eye-bank eyes using A-scan. Surge was simulated by clamping the aspiration tubing and releasing it at maximum vacuum. In both machines, surge was measured (1) with aspiration held constant at 12 mL/min and bottle heights at 60, 120, and 180 cm and (2) with bottle height held constant at 60 cm and aspiration rates at 12, 24, and 36 mL/min. Surge decreased approximately 40% with each 60 cm increase in bottle height in the Infiniti. It was constant at all bottle heights in the Millennium. At 12 and 24 mL/min aspiration rates, surge in the Millennium was less than half that in the Infiniti (P<.001). Postocclusion surge decreased linearly with increasing bottle height in the Infiniti system and was relatively constant with increasing bottle height in the Millennium system. The Millennium may offer a more stable phacoemulsification platform with respect to surge at a higher aspiration rate.

Assessing bottled water nitrate concentrations to evaluate total drinking water nitrate exposure and risk of birth defects

PubMed Central

Weyer, Peter J.; Brender, Jean D.; Romitti, Paul A.; Kantamneni, Jiji R.; Crawford, David; Sharkey, Joseph R.; Shinde, Mayura; Horel, Scott A.; Vuong, Ann M.; Langlois, Peter H.

2016-01-01

Previous epidemiologic studies of maternal exposure to drinking water nitrate did not account for bottled water consumption. The objective of this National Birth Defects Prevention Study (NBDPS) (USA) analysis was to assess the impact of bottled water use on the relation between maternal exposure to drinking water nitrate and selected birth defects in infants born during 1997–2005. Prenatal residences of 1,410 mothers reporting exclusive bottled water use were geocoded and mapped; 326 bottled water samples were collected and analyzed using Environmental Protection Agency Method 300.0. Median bottled water nitrate concentrations were assigned by community; mothers’ overall intake of nitrate in mg/day from drinking water was calculated. Odds ratios for neural tube defects, limb deficiencies, oral cleft defects, and heart defects were estimated using mixed-effects models for logistic regression. Odds ratios (95% CIs) for the highest exposure group in offspring of mothers reporting exclusive use of bottled water were: neural tube defects [1.42 (0.51, 3.99)], limb deficiencies [1.86 (0.51, 6.80)], oral clefts [1.43 (0.61, 3.31)], and heart defects [2.13, (0.87, 5.17)]. Bottled water nitrate had no appreciable impact on risk for birth defects in the NBDPS. PMID:25473985

Light-induced changes in bottled white wine and underlying photochemical mechanisms.

PubMed

Grant-Preece, Paris; Barril, Celia; Schmidtke, Leigh M; Scollary, Geoffrey R; Clark, Andrew C

2017-03-04

Bottled white wine may be exposed to UV-visible light for considerable periods of time before it is consumed. Light exposure may induce an off-flavor known as "sunlight" flavor, bleach the color of the wine, and/or increase browning and deplete sulfur dioxide. The changes that occur in bottled white wine exposed to light depend on the wine composition, the irradiation conditions, and the light exposure time. The light-induced changes in the aroma, volatile composition, color, and concentrations of oxygen and sulfur dioxide in bottled white wine are reviewed. In addition, the photochemical reactions thought to have a role in these changes are described. These include the riboflavin-sensitized oxidation of methionine, resulting in the formation of methanethiol and dimethyl disulfide, and the photodegradation of iron(III) tartrate, which gives rise to glyoxylic acid, an aldehyde known to react with flavan-3-ols to form yellow xanthylium cation pigments.

10 CFR 431.294 - Uniform test method for the measurement of energy consumption of refrigerated bottled or canned...

Code of Federal Regulations, 2010 CFR

2010-01-01

... consumption of refrigerated bottled or canned beverage vending machines. 431.294 Section 431.294 Energy... method for the measurement of energy consumption of refrigerated bottled or canned beverage vending... test procedure for energy consumption of refrigerated bottled or canned beverage vending machines shall...

Effect of wine pH and bottle closure on tannins.

PubMed

McRae, Jacqui M; Kassara, Stella; Kennedy, James A; Waters, Elizabeth J; Smith, Paul A

2013-11-27

The impact of wine pH and closure type on color, tannin concentration, and composition was investigated. A single vintage of Cabernet Sauvignon wine was divided into three batches, the pH was adjusted to 3.2, 3.5 or 3.8, and the wines were bottled under screw caps with either SaranTin (ST) or Saranex (Sx) liners. After 24 months, the tannin concentration, tannin percent yield (relating to the proportion of acid-labile interflavan bonds), and the mean degree of polymerization (mDp) had decreased significantly, all of which can contribute to the softening of wine astringency with aging. The higher pH wines contained less percent (-)-epicatechin 3-O-gallate subunits, whereas the Sx pH 3.2 wines were significantly lower in percent yield and mDp than the other wines. Overall, the tannin structure and wine color of the lower pH wines (pH 3.2) bottled under Sx screw caps changed more rapidly with aging than those of the higher pH wines (pH 3.8) bottled under ST screw caps.

ICTV Virus Taxonomy Profile: Virgaviridae

USDA-ARS?s Scientific Manuscript database

The family Virgaviridae is comprised of plant-infecting viruses with rod-shaped particles, single stranded RNA genomes with 3' terminal tRNA-like structures, and replication proteins typical of alphalike viruses. Differences in the number of genome components, genome organization and transmission m...

Identification and quantification of the migration of chemicals from plastic baby bottles used as substitutes for polycarbonate.

PubMed

Simoneau, C; Van den Eede, L; Valzacchi, S

2012-01-01

The results of a study on the analytical identification and quantification of migration of chemicals from plastics baby bottles found in the European Union market made of materials that are now present as substitutes for polycarbonate (PC) are reported. A total of 449 baby bottles with a focus on first age or sets of bottles were purchased from 26 European Union countries, Canada, Switzerland and the USA. From this collection, which contained several duplicates, a total of 277 baby bottles were analysed. The materials included different types of plastic such as PC, polyamide (PA), polyethersulphone (PES), polypropylene (PP), but also silicone, and from the United States a co-polyester marketed under the trade name Tritan™. The bottles were subjected to the conventional migration test for hot fill conditions, i.e. 2 h at 70°C. The simulant used was that specified in European Union legislation (2007/19/EC) for milk, i.e. 50% ethanol. In a first phase 1, migration was conducted since the scope of this investigation was a screening rather than a true compliance testing check. Second and third migrations were performed on selected articles when migrated substances exceeded limits specified in the legislation. In order to verify some materials, a portion of the bottle was cut to run an FT-IR fingerprint to confirm the nature of the polymer. The migration solutions in general showed a low release of substances. Results showed that bottles made of PP and silicones showed a greater number of substances in the migration solutions and in greater quantity. Chemicals from PP included alkanes, which could be found in >65% of the bottles at levels up to 3500 µg kg⁻¹; and benzene derivatives in 17% of the baby bottles and found at levels up to 113 µg kg⁻¹. Some substances were found on a regular basis such as plasticisers, esters and antioxidants (e.g. tris(2,4-di-tert-butylphenyl)phosphate, known as Irgafos 168. Some substances found were not included in the

Office-based intervention to reduce bottle use among toddlers: TARGet Kids! Pragmatic, randomized trial.

PubMed

Maguire, Jonathon L; Birken, Catherine S; Jacobson, Sheila; Peer, Michael; Taylor, Carolyn; Khambalia, Amina; Mekky, Magda; Thorpe, Kevin E; Parkin, Patricia

2010-08-01

The goal was to determine whether an office-based, educational intervention for parents of 9-month-old children could reduce bottle use and iron depletion at 2 years of age. Between January 2006 and 2007, 251 healthy, 9-month-old infants attending a routine health maintenance visit were assigned randomly to intervention or control groups. Parents in the intervention group were introduced to a 1-week protocol to wean their children from the bottle. Iron depletion (ferritin levels of <10 microg/L) and bottle use at 2 years were assessed. A total of 201 children were monitored to 2 years of age (follow-up rate: 81%). Rates of iron depletion (10 [10%] of 102 children vs 13 [13%] of 99 children; P = .42) and milk consumption of >16 oz (16 [16%] of 102 children vs 17 [17%] of 99 children; P = .7) were not significantly different between the 2 groups at 2 years of age. However, children in the intervention group started using a cup 3 months earlier (9 vs 12 months; P = .001), were weaned from the bottle 4 months earlier (12 vs 16 months; P = .004), and were more than one-half as likely to be using a bottle at 2 years of age (15 [15%] of 102 children vs 39 [40%] of 99 children; P = .0004). This simple intervention administered during a health maintenance visit did not result in a decrease in iron depletion at 2 years of age but did result in a 60% reduction in prolonged bottle use.

The Egg in the Bottle Revisited: Air Pressure and Amontons' Law (Charles' Law).

ERIC Educational Resources Information Center

Adcock, Louis H.

1998-01-01

Presents instructions for putting a hard-boiled egg inside a bottle whose opening is slightly smaller than the egg's circumference, and for getting the egg out of the bottle. Also describes variations of the demonstration such as cooling the flask or using a banana. Cites incorrect and correct explanations of the demonstrated phenomenon. Contains…

Bottle gourd genotypes vary in clomazone tolerance

USDA-ARS?s Scientific Manuscript database

A greenhouse trial was used to evaluate 159 accessions of bottle gourd (Lagenaria siceraria (Mol.) Standl.) obtained from the U.S. National Plant Germplasm for tolerance to clomazone herbicide. Most accessions tested were moderately or severely injured by clomazone at 3.0 mg/kg incorporated into gr...

Squeeze bottle apparatus with force multiplying pistons

DOEpatents

Moss, Owen R.; Gordon, Norman R.; DeFord, Henry S.; Eschbach, Eugene A.

1994-01-01

The present invention comprises a spray bottle in which the pressure resulting from the gripping force applied by the user is amplified and this increased pressure used in generating a spray such as an aerosol or fluid stream. In its preferred embodiment, the invention includes a high pressure chamber and a corresponding piston which is operative for driving fluid out of this chamber at high pressure through a spray nozzle and a low pressure chamber, and a corresponding piston which is acted upon by the hydraulic pressure within the bottle resulting from the gripping force. The low pressure chamber and piston are of larger size than the high pressure chamber and piston. The pistons are rigidly connected so that the force created by the pressure acting on the piston in the low pressure chamber is transmitted to the piston in the high pressure chamber where it is applied over a more limited area, thereby generating greater hydraulic pressure for use in forming the spray.

Spray bottle apparatus with pressure multiplying pistons

DOEpatents

Moss, Owen R.; Gordon, Norman R.; DeFord, Henry S.

1990-01-01

The present invention comprises a spray bottle in which the pressure resulting from the gripping force applied by the user is amplified and this increased pressure used in generating a spray such as an aerosol or fluid stream. In its preferred embodiment, the invention includes a high pressure chamber and a corresponding piston which is operative for driving fluid out of this chamber at high pressure through a spray nozzle and a low pressure chamber and a corresponding piston which is acted upon the hydraulic pressure within the bottle resulting from the gripping force. The low pressure chamber and piston are of larger size than the high pressure chamber and piston. The pistons are rigidly connected so that the force created by the pressure acting on the piston in the low pressure chamber is transmitted to the piston in the high pressure chamber where it is applied over a more limited area thereby generating greater hydraulic pressure for use in forming the spray.

Spray bottle apparatus with force multiply pistons

DOEpatents

Eschbach, Eugene A.

1992-01-01

The present invention comprises a spray bottle in which the pressure resulting from the gripping force applied by the user is amplified and this increased pressure used in generating a spray such as an aerosol or fluid stream. In its preferred embodiment, the invention includes a high pressure chamber and a corresponding piston which is operative for driving fluid out of this chamber at high pressure through a spray nozzle and a low pressure chamber and corresponding piston which is acted upon by the hydraulic pressure within the bottle resulting from the gripping force. The low pressure chamber and piston are of larger size than the high pressure chamber and piston. The pistons are rigidly connected so that the force created by the pressure acting on the piston in the low pressure chamber is transmitted to the piston in the high pressure chamber where it is applied over a more limited area thereby generating greater hydraulic pressure for use in forming the spray.

Bottled beverages and typhoid fever: the Mexican epidemic of 1972-73.

PubMed Central

Gonzalez-Cortes, A; Gangarosa, E J; Parrilla, C; Martin, W T; Espinosa-Ayala, A M; Ruiz, L; Bessudo, D; Hernandez-Arreortua, H

1982-01-01

A chloramphenicol resistant strain of S. typhi which caused a very large epidemic of typhoid fever in Mexico in 1972-73 survived in opened bottles of one carbonated drink with a pH of 4.6 for two weeks and in another such drink with a pH of 5.1 for six months. Bottled beverages are potential sources of large outbreaks of enteric disease, and deserve the same type of standards sand monitoring as comparable fluids such as milk. PMID:7091481

Microbiological Investigations of ReNu Plastic Bottles and the 2004 to 2006 ReNu With MoistureLoc-Related Worldwide Fusarium Keratitis Event.

PubMed

Bullock, John D; Warwar, Ronald E; Elder, B Laurel; Khamis, Harry J

2016-05-01

The purposes of this study were to determine whether the contact lens solution RevitaLens Ocutec (containing the antimicrobial agents alexidine and polyquaternium-1) would inhibit Fusarium organisms when heated in ReNu plastic bottles; whether alexidine would inhibit Fusarium organisms when heated in non-ReNu plastic bottles; and whether an alexidine-neutralizing compound leaches from heated ReNu bottles. RevitaLens and an alexidine solution (0.00045%), previously stored in ReNu bottles at room temperature (RT) and 56°C, were incubated with 7 different Fusarium organisms. The alexidine solution was similarly stored in seven non-ReNu plastic bottles and incubated with these same organisms. To determine if an alexidine-neutralizing compound might be leaching from heated ReNu bottles, phosphate-buffered saline (PBS) was incubated at RT and 56°C in ReNu bottles, combined with alexidine, and then tested for anti-Fusarium capability. After being heated in ReNu bottles, RevitaLens retained its anti-Fusarium capability, whereas the alexidine solution did not. The alexidine solution heated in seven non-ReNu plastic bottles retained its anti-Fusarium capability. The alexidine solution retained its anti-Fusarium capability when incubated with a PBS solution that had been heated in ReNu bottles, indicating, microbiologically, that an alexidine-neutralizing compound did not leach from the heated ReNu bottle. Alexidine uniquely fails to inhibit Fusarium organisms when heated in a plastic ReNu bottle, but not in seven other plastic bottles, whereas the anti-Fusarium capability of RevitaLens (containing the antimicrobial agents alexidine and polyquaternium-1) is unaffected by heating in a ReNu bottle. There does not seem to be an alexidine-neutralizing compound leaching from heated ReNu bottles. An interaction between alexidine and its heated ReNu bottle may have been a critical factor in the worldwide ReNu with MoistureLoc-related Fusarium keratitis event of 2004 to 2006.

Coordination of hand shape.

PubMed

Pesyna, Colin; Pundi, Krishna; Flanders, Martha

2011-03-09

The neural control of hand movement involves coordination of the sensory, motor, and memory systems. Recent studies have documented the motor coordinates for hand shape, but less is known about the corresponding patterns of somatosensory activity. To initiate this line of investigation, the present study characterized the sense of hand shape by evaluating the influence of differences in the amount of grasping or twisting force, and differences in forearm orientation. Human subjects were asked to use the left hand to report the perceived shape of the right hand. In the first experiment, six commonly grasped items were arranged on the table in front of the subject: bottle, doorknob, egg, notebook, carton, and pan. With eyes closed, subjects used the right hand to lightly touch, forcefully support, or imagine holding each object, while 15 joint angles were measured in each hand with a pair of wired gloves. The forces introduced by supporting or twisting did not influence the perceptual report of hand shape, but for most objects, the report was distorted in a consistent manner by differences in forearm orientation. Subjects appeared to adjust the intrinsic joint angles of the left hand, as well as the left wrist posture, so as to maintain the imagined object in its proper spatial orientation. In a second experiment, this result was largely replicated with unfamiliar objects. Thus, somatosensory and motor information appear to be coordinated in an object-based, spatial-coordinate system, sensitive to orientation relative to gravitational forces, but invariant to grasp forcefulness.

Generation of acoustic self-bending and bottle beams by phase engineering

NASA Astrophysics Data System (ADS)

Zhang, Peng; Li, Tongcang; Zhu, Jie; Zhu, Xuefeng; Yang, Sui; Wang, Yuan; Yin, Xiaobo; Zhang, Xiang

2014-07-01

Directing acoustic waves along curved paths is critical for applications such as ultrasound imaging, surgery and acoustic cloaking. Metamaterials can direct waves by spatially varying the material properties through which the wave propagates. However, this approach is not always feasible, particularly for acoustic applications. Here we demonstrate the generation of acoustic bottle beams in homogeneous space without using metamaterials. Instead, the sound energy flows through a three-dimensional curved shell in air leaving a close-to-zero pressure region in the middle, exhibiting the capability of circumventing obstacles. By designing the initial phase, we develop a general recipe for creating self-bending wave packets, which can set acoustic beams propagating along arbitrary prescribed convex trajectories. The measured acoustic pulling force experienced by a rigid ball placed inside such a beam confirms the pressure field of the bottle. The demonstrated acoustic bottle and self-bending beams have potential applications in medical ultrasound imaging, therapeutic ultrasound, as well as acoustic levitations and isolations.

27 CFR 27.204 - Distinctive liquor bottles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Distinctive liquor bottles. 27.204 Section 27.204 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL IMPORTATION OF DISTILLED SPIRITS, WINES, AND BEER Requirements for Liquor...

27 CFR 27.204 - Distinctive liquor bottles.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Distinctive liquor bottles. 27.204 Section 27.204 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL IMPORTATION OF DISTILLED SPIRITS, WINES, AND BEER Requirements for Liquor...

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans.

PubMed

Grifoni, Alba; Pham, John; Sidney, John; O'Rourke, Patrick H; Paul, Sinu; Peters, Bjoern; Martini, Sheridan R; de Silva, Aruna D; Ricciardi, Michael J; Magnani, Diogo M; Silveira, Cassia G T; Maestri, Alvino; Costa, Priscilla R; de-Oliveira-Pinto, Luzia Maria; de Azeredo, Elzinandes Leal; Damasco, Paulo Vieira; Phillips, Elizabeth; Mallal, Simon; de Silva, Aravinda M; Collins, Matthew; Durbin, Anna; Diehl, Sean A; Cerpas, Cristhiam; Balmaseda, Angel; Kuan, Guillermina; Coloma, Josefina; Harris, Eva; Crowe, James E; Stone, Mars; Norris, Phillip J; Busch, Michael; Vivanco-Cid, Hector; Cox, Josephine; Graham, Barney S; Ledgerwood, Julie E; Turtle, Lance; Solomon, Tom; Kallas, Esper G; Watkins, David I; Weiskopf, Daniela; Sette, Alessandro

2017-10-04

While progress has been made in characterizing humoral immunity to Zika virus (ZIKV) in humans, little is known regarding the corresponding T cell responses to ZIKV. Here we investigate the kinetics and viral epitopes targeted by T cells responding to ZIKV and address the critical question of whether pre-existing dengue virus (DENV) T cell immunity modulates these responses. We find that memory T cell responses elicited by prior infection with DENV or vaccination with Tetravalent Dengue Attenuated Vaccines (TDLAV) recognize ZIKV-derived peptides. This cross-reactivity is explained by the sequence similarity of the two viruses, as the ZIKV peptides recognized by DENV-elicited memory T cells are identical or highly conserved in DENV and ZIKV. DENV exposure prior to ZIKV infection also influences the timing and magnitude of the T cell response. ZIKV-reactive T cells in the acute phase of infection are detected earlier and in greater magnitude in DENV-immune patients. Conversely, the frequency of ZIKV-reactive T cells continues to rise in the convalescent phase in DENV-naive donors, but declines in DENV pre-exposed donors, compatible with more efficient control of ZIKV replication and/or clearance of ZIKV antigen. The quality of responses is also influenced by previous DENV exposure, and ZIKV-specific CD8 T cells form DENV pre-exposed donors selectively up-regulated granzyme B and PD1, as compared to DENV-naïve donors. Finally, we discovered that ZIKV structural proteins (E, prM and C) are major targets of both the CD4 and CD8 T cell responses, whereas DENV T cell epitopes are found primarily in nonstructural proteins. IMPORTANCE The issue of potential ZIKV and DENV cross-reactivity and how pre-existing DENV T cell immunity modulates ZIKA T cell responses is of great relevance as the two viruses often co-circulate and ZIKA virus has been spreading in geographical regions where DENV is endemic or hyper-endemic. Our data show that memory T cell responses elicited by

Polymer brush coatings for DNA: fundamental polymer physics and nanofabrication applications

NASA Astrophysics Data System (ADS)

de Vries, Renko

Recombinant DNA technology allows for the production of precisely defined self-assembling protein-based polymers. So far, the major applications for such protein-based polymers have been self-assembling hydrogels and micellar structures with biomedical application. Inspired by minimal models for the self-ssembly of rod-shaped viruses such as the tobacco mosaic virus, I have developed protein-polymers that co-assemble with DNA into rod-shaped virus-like particles, and protein-polymers that provide brush coatings around single DNA molecules. In this presentation I will focus on the latter, showing that on the one hand brush coated DNA is a rich model system for exploring the physics of bottle-brush polymers, while on the other hand brush coatings of DNA can also play an important practical role in nanofabrication. A key problem in the physics of bottle-brush polymers that I will address is the scale-dependence of bottle-brush elasticity. For long-wavelength thermal deformations probed by AFM imaging I will demonstrate that there is significant stiffening due to the brush coating, while for short wavelength thermal deformations probed by force spectroscopy, we find that stiffening due to the brush coating disappears completely. DNA brush coatings can also play an important practical role in nanofabrication by acting as a compatibilizer between chemically different building blocks. I will explore the example of DNA origami in combination with gold nanoparticles: while Mg2+ ions and high concentrations of monovalent salts are crucial for the stability of DNA origami, such solution conditions are typically incompatible with the colloidal stability of gold nanoparticles.I will show how DNA brush coatings can dramatically enhance the yield of formation of isolated DNA-gold nanoparticle composite nanostructures.

Effects of Water Bottle Materials and Filtration on Bisphenol A Content in Laboratory Animal Drinking Water.

PubMed

Honeycutt, Jennifer A; Nguyen, Jenny Q T; Kentner, Amanda C; Brenhouse, Heather C

2017-05-01

Bisphenol A (BPA) is widely used in the polycarbonate plastics and epoxy resins that are found in laboratory animal husbandry materials including cages and water bottles. Concerns about BPA exposure in humans has led to investigations that suggest physiologic health risks including disruptions to the endocrine system and CNS. However, the extent of exposure of laboratory animals to BPA in drinking water is unclear. In the first study, we compared the amount of BPA contamination in water stored in plastic bottles used in research settings with that in glass bottles. The amount of BPA that leached into water was measured across several time points ranging from 24 to 96 h by using a BPA ELISA assay. The results showed that considerable amounts of BPA (approximately 0.15 μg/L) leached from polycarbonate bottles within the first 24 h of storage. In the second study, BPA levels were measured directly from water taken from filtered compared with unfiltered taps. We observed significantly higher BPA levels in water from unfiltered taps (approximately 0.40 μg/L) compared with taps with filtration systems (approximately 0.04 μg/L). Taken together, our findings indicate that the use of different types of water bottles and water sources, combined with the use of different laboratory products (food, caging systems) between laboratories, likely contribute to decreased rigor and reproducibility in research. We suggest that researchers consider reporting the types of water bottles used and that animal care facilities educate staff regarding the importance of flushing nonfiltered water taps when filling animal water bottles.

Effects of Water Bottle Materials and Filtration on Bisphenol A Content in Laboratory Animal Drinking Water

PubMed Central

Honeycutt, Jennifer A; Nguyen, Jenny Q T; Kentner, Amanda C; Brenhouse, Heather C

2017-01-01

Bisphenol A (BPA) is widely used in the polycarbonate plastics and epoxy resins that are found in laboratory animal husbandry materials including cages and water bottles. Concerns about BPA exposure in humans has led to investigations that suggest physiologic health risks including disruptions to the endocrine system and CNS. However, the extent of exposure of laboratory animals to BPA in drinking water is unclear. In the first study, we compared the amount of BPA contamination in water stored in plastic bottles used in research settings with that in glass bottles. The amount of BPA that leached into water was measured across several time points ranging from 24 to 96 h by using a BPA ELISA assay. The results showed that considerable amounts of BPA (approximately 0.15 μg/L) leached from polycarbonate bottles within the first 24 h of storage. In the second study, BPA levels were measured directly from water taken from filtered compared with unfiltered taps. We observed significantly higher BPA levels in water from unfiltered taps (approximately 0.40 μg/L) compared with taps with filtration systems (approximately 0.04 μg/L). Taken together, our findings indicate that the use of different types of water bottles and water sources, combined with the use of different laboratory products (food, caging systems) between laboratories, likely contribute to decreased rigor and reproducibility in research. We suggest that researchers consider reporting the types of water bottles used and that animal care facilities educate staff regarding the importance of flushing nonfiltered water taps when filling animal water bottles. PMID:28535862

Treatment of Bottled Liquid Waste During Remediation of the Hanford 618-10 Burial Ground - 13001

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faulk, Darrin E.; Pearson, Chris M.; Vedder, Barry L.

2013-07-01

A problematic waste form encountered during remediation of the Hanford Site 618-10 burial ground consists of bottled aqueous waste potentially contaminated with regulated metals. The liquid waste requires stabilization prior to landfill disposal. Prior remediation activities at other Hanford burial grounds resulted in a standard process for sampling and analyzing liquid waste using manual methods. Due to the highly dispersible characteristics of alpha contamination, and the potential for shock sensitive chemicals, a different method for bottle processing was needed for the 618-10 burial ground. Discussions with the United States Department of Energy (DOE) and United States Environmental Protection Agency (EPA)more » led to development of a modified approach. The modified approach involves treatment of liquid waste in bottles, up to one gallon per bottle, in a tray or box within the excavation of the remediation site. Bottles are placed in the box, covered with soil and fixative, crushed, and mixed with a Portland cement grout. The potential hazards of the liquid waste preclude sampling prior to treatment. Post treatment verification sampling is performed to demonstrate compliance with land disposal restrictions and disposal facility acceptance criteria. (authors)« less

The health-related microbiological quality of bottled drinking water sold in Dar es Salaam, Tanzania.

PubMed

Kassenga, Gabriel R

2007-03-01

The consumption of bottled and plastic-bagged drinking water in Tanzania has increased largely because of the deteriorating quality of tap water. It is uncertain whether these water products are safe for drinking. In this study, the microbiological quality of bottled and plastic-bagged drinking water sold in Dar es Salaam, Tanzania, was investigated. One hundred and thirty samples representing 13 brands of bottled water collected from shops, supermarkets and street vendors were analysed for total coliform and faecal coliform organisms as well as heterotrophic bacteria. These were compared with 61 samples of tap water. Heterotrophic bacteria were detected in 92% of the bottled water samples analysed. Total and faecal coliform bacteria were present in 4.6% and 3.6%, respectively, of samples analysed with a tendency for higher contamination rates in plastic-bagged drinking water. Microbiological quality of tap water was found to be worse compared with bottled water, with 49.2% and 26.2% of sampling points showing the presence of total coliform and faecal coliform organisms, respectively. The results suggest caution and vigilance to avert outbreaks of waterborne diseases from these types of drinking water.

Analytical and computational modeling of early penetration of non-enveloped icosahedral viruses into cells.

PubMed

Katzengold, Rona; Zaharov, Evgeniya; Gefen, Amit

2016-07-27

As obligate intracellular parasites, all viruses penetrate target cells to initiate replication and infection. This study introduces two approaches for evaluating the contact loads applied to a cell during early penetration of non-enveloped icosahedral viruses. The first approach is analytical modeling which is based on Hertz's theory for the contact of two elastic bodies; here we model the virus capsid as a triangle and the cell as an order-of-magnitude larger sphere. The second approach is finite element modeling, where we simulate three types of viruses: adeno-, papilloma- and polio- viruses, each interacting with a cell section. We find that the peak contact pressures and forces generated at the initial virus-cell contact depend on the virus geometry - that is both size and shape. With respect to shape, we show that the icosahedral virus shape induces greater peak pressures compared to a spherical virus shape. With respect to size, it is shown that the larger the virus is the greater are the contact loads in the attacked cell. Utilization of our modeling can be substantially useful not only for basic science studies, but also in other, more applied fields, such as in the field of gene therapy, or in `phage' virus studies.

[Development of a screening scale for children at risk of baby bottle tooth decay].

PubMed

Khadra-Eid, J; Baudet, D; Fourny, M; Sellier, E; Brun, C; François, P

2012-03-01

Baby bottle tooth decay is a severe form of early childhood caries. This study aims to elaborate a screening tool for at risk children in order to facilitate primary prevention. A case-control study was conducted among children suffering from baby bottle tooth decay and children with no dental caries. Cases were children aged 5 years or less at diagnosis who experienced at least four caries with one or more affecting maxillary incisors. Controls were children matched for age and sex. Parents were interviewed by phone about their child's exposure to potential risk factors. We included 88 children suffering from baby bottle tooth decay and 88 children with no dental caries. In multivariate analysis, low social class (OR 6.39 [95% CI, 1.45-28.11]), prolonged bottle feeding or bedtime feeding (OR 153.2 [95% CI, 11.77-1994.96]), and snacking (OR 5.94 [95% CI, 1.35-26.2]) were significantly associated with baby bottle tooth decay. Regular dental visits were a significant protecting factor (OR 0.13 [95% CI, 0.02-0.77]). A score was developed using these significant risk factors and tested on the survey population. The mean score was 13/20 for cases and 4/20 for controls. These results are in accordance with the literature, except for brushing teeth, which was not significantly associated with baby bottle tooth decay in our study. A screening scale with a score of 20 points was proposed. Future validation is required. Pediatricians and general practitioners should encourage parents to change their habits. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

27 CFR 27.204 - Distinctive liquor bottles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Distinctive liquor bottles. 27.204 Section 27.204 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU..., to Customs officials at each affected port of entry where the merchandise is examined. (Sec. 201, Pub...

27 CFR 27.204 - Distinctive liquor bottles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Distinctive liquor bottles. 27.204 Section 27.204 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU..., to Customs officials at each affected port of entry where the merchandise is examined. (Sec. 201, Pub...

27 CFR 26.314 - Distinctive liquor bottles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Distinctive liquor bottles. 26.314 Section 26.314 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Requirements...

Quality control of bottled and vended water in California: A review and comparison to tap water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darby, J.L.; Allen, L.

1994-04-01

Current regulations and compliance for quality control of bottled and vended water in California are compared with that of the tap water industry in this research. Over 35% of the bottled water sold in the US is consumed in California where a third of the residents use such water as a primary source of drinking water. California is one of several states that regulates bottled water more rigorously than the federal government. In California, water quality standards for the two industries are comparable except that many of the organic standards for bottled water are applicable only to the source water,more » a concern due to potential organic contamination during processing. Reporting requirements, significantly less stringent for bottled water, allow considerable latitude in assessing risks and make assessment of compliance difficult. Based on available statistics, compliance for the two industries is comparable; the majority of violations posed no health risks. For both industries, small systems comprised the majority of violations whereas large systems had excellent compliance rates.« less

Eliminating the use of intravenous glass bottles using a FOCUS-PDCA model and providing a practical stability reference guide.

PubMed

Maraiki, Fatma; Farooq, Faiyaz; Ahmed, Mohamed

2016-08-01

To identify the intravenous (IV) medications that are prepared in glass bottles at the institution and establish which of these medications can be prepared in flexible IV bags such as polyvinyl chloride (PVC) or non-PVC instead of glass bottles. The cost implication of switching from glass bottles to flexible IV bags was calculated. A study using FOCUS-PDCA model to identify IV medications prepared in glass bottles and establish which of these medications could be prepared in IV bags (PVC or non-PVC). The cost impact of switching from glass bottles to IV plastic bags (including PVC or non-PVC) was calculated. The stability data obtained were used as a reference for updating pharmacy internal IV preparation charts. A total of 17 IV medications were found to be prepared in IV glass bottles. Of these 17 medications, only 8 (47%) were prepared in IV glass bottles due to incompatibility with PVC bags. For 7 (41%) of the medications, of which 6 were monoclonal antibodies (MABs), the reason for preparation in glass bottles was unclear as these medications are compatible with either PVC or non-PVC or both. The potential cost savings associated with switching all of the identified medications to IV plastic bags (either non-PVC or PVC) exceeded $200 000. The elimination of glass bottles within the institution resulted in a significant cost saving. The use of FOCUS-PDCA model can help healthcare institution achieve significant improvements in process and realize significant cost savings. © 2016 Royal Pharmaceutical Society.

Adaptation and evaluation of the bottle assay for monitoring insecticide resistance in disease vector mosquitoes in the Peruvian Amazon

PubMed Central

Zamora Perea, Elvira; Balta León, Rosario; Palomino Salcedo, Miriam; Brogdon, William G; Devine, Gregor J

2009-01-01

Background The purpose of this study was to establish whether the "bottle assay", a tool for monitoring insecticide resistance in mosquitoes, can complement and augment the capabilities of the established WHO assay, particularly in resource-poor, logistically challenging environments. Methods Laboratory reared Aedes aegypti and field collected Anopheles darlingi and Anopheles albimanus were used to assess the suitability of locally sourced solvents and formulated insecticides for use with the bottle assay. Using these adapted protocols, the ability of the bottle assay and the WHO assay to discriminate between deltamethrin-resistant Anopheles albimanus populations was compared. The diagnostic dose of deltamethrin that would identify resistance in currently susceptible populations of An. darlingi and Ae. aegypti was defined. The robustness of the bottle assay during a surveillance exercise in the Amazon was assessed. Results The bottle assay (using technical or formulated material) and the WHO assay were equally able to differentiate deltamethrin-resistant and susceptible An. albimanus populations. A diagnostic dose of 10 μg a.i./bottle was identified as the most sensitive discriminating dose for characterizing resistance in An. darlingi and Ae. aegypti. Treated bottles, prepared using locally sourced solvents and insecticide formulations, can be stored for > 14 days and used three times. Bottles can be stored and transported under local conditions and field-assays can be completed in a single evening. Conclusion The flexible and portable nature of the bottle assay and the ready availability of its components make it a potentially robust and useful tool for monitoring insecticide resistance and efficacy in remote areas that require minimal cost tools. PMID:19728871

27 CFR 5.41 - Bottle cartons, booklets and leaflets.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF DISTILLED SPIRITS Labeling...), or any written, printed, graphic, or other matter accompanying the bottle to the consumer buyer shall...

[Reliability of % vol. declarations on labels of wine bottles].

PubMed

Schütz, Harald; Erdmann, Freidoon; Verhoff, Marcel A; Weiler, Günter

2005-01-01

The Council Regulation (EC) no. 1493/1999 of 17 May 1999 on the common organisation of the market in wine (Abl. L 179 dated 14/7/1999) and the GMO Wine 2000 (Annex VII A) stipulates that the labels of wine bottles have to indicate, among others, information on the sales designation of the product, the nominal volume and the alcoholic strength. The latter must not differ by more than 0.5% vol. from the alcoholic strength as established by analysis. Only when quality wines are stored in bottles for more than three years, the accepted tolerance limits are +/- 0.8% vol. The presented investigation results show that deviations have to be taken into account which may be highly relevant for forensic practice.

Fluoride Content of Bottled Waters in Hong Kong and Qatar.

PubMed

Al-Mulla, Hessa I; Anthonappa, Robert P; King, Nigel M

2016-01-01

To determine the F concentration of bottled waters that was available in Hong Kong and Qatar. The F concentrations of bottled waters collected from Hong Kong (n=81) and Qatar (n=32) were analysed. The F ion selective electrode method was used to measure the F concentration in the samples. Three measurements were obtained for every sample to ensure reproducibility and appropriate statistical analyses were employed. Qatar group: F concentrations ranged from 0.06 ppm to 3.0 ppm with a mean value of 0.8 ppm. The F concentrations displayed on the labels of the samples (60%) were significantly lower than the measured F concentration (p < 0.0001). Hong Kong group: F concentrations ranged from 0.04 ppm to 2.52 ppm with a mean value of 0.44 ppm. The F concentrations displayed on the samples (16%) were significantly lower than the measured F concentration (p< 0.0001). Wide variations exist in the F concentration among the different brands of bottled water available in Hong Kong and Qatar. The F concentrations displayed on the labels were not consistent with the measured F concentrations.

Orpheovirus IHUMI-LCC2: A New Virus among the Giant Viruses

PubMed Central

Andreani, Julien; Khalil, Jacques Y. B.; Baptiste, Emeline; Hasni, Issam; Michelle, Caroline; Raoult, Didier; Levasseur, Anthony; La Scola, Bernard

2018-01-01

Giant viruses continue to invade the world of virology, in gigantic genome sizes and various particles shapes. Strains discoveries and metagenomic studies make it possible to reveal the complexity of these microorganisms, their origins, ecosystems and putative roles. We isolated from a rat stool sample a new giant virus “Orpheovirus IHUMI-LCC2,” using Vermamoeba vermiformis as host cell. In this paper, we describe the main genomic features and replicative cycle of Orpheovirus IHUMI-LCC2. It possesses a circular genome exceeding 1.4 Megabases with 25% G+C content and ovoidal-shaped particles ranging from 900 to 1300 nm. Particles are closed by at least one thick membrane in a single ostiole-like shape in their apex. Phylogenetic analysis and the reciprocal best hit for Orpheovirus show a connection to the proposed Pithoviridae family. However, some genomic characteristics bear witness to a completely divergent evolution for Orpheovirus IHUMI-LCC2 when compared to Cedratviruses or Pithoviruses. PMID:29403444

Glass-on-Glass Fabrication of Bottle-Shaped Tunable Microlasers and their Applications

PubMed Central

Ward, Jonathan M.; Yang, Yong; Nic Chormaic, Síle

2016-01-01

We describe a novel method for making microbottle-shaped lasers by using a CO2 laser to melt Er:Yb glass onto silica microcapillaries or fibres. This is realised by the fact that the two glasses have different melting points. The CO2 laser power is controlled to flow the doped glass around the silica cylinder. In the case of a capillary, the resulting geometry is a hollow, microbottle-shaped resonator. This is a simple method for fabricating a number of glass whispering gallery mode (WGM) lasers with a wide range of sizes on a single, micron-scale structure. The Er:Yb doped glass outer layer is pumped at 980 nm via a tapered optical fibre and WGM lasing is recorded around 1535 nm. This structure facilitates a new way to thermo-optically tune the microlaser modes by passing gas through the capillary. The cooling effect of the gas flow shifts the WGMs towards shorter wavelengths and thermal tuning of the lasing modes over 70 GHz is achieved. Results are fitted using the theory of hot wire anemometry, allowing the flow rate to be calibrated with a flow sensitivity as high as 72 GHz/sccm. Strain tuning of the microlaser modes by up to 60 GHz is also demonstrated. PMID:27121151

Physicochemical quality and health implications of bottled water brands sold in Ethiopia.

PubMed

Amogne, Wossen T; Gizaw, Melaku; Abera, Daniel

2015-06-01

Water bottling companies often assert that their products are of the highest quality and are conforming to the standards. The objective of the study was to assess the physicochemical quality of bottled waters consumed in Ethiopia and to compare the findings with the national and international water quality standards. Eleven domestic and two imported bottled water brands were randomly purchased in Addis Ababa, Ethiopia at three different occasions from July 2013 to May 2014. A total of 39 composite samples were examined for aggregate parameters, major anions, and common cations in accordance with the procedures described in the standard methods. We found that 7.7% of the samples were containing higher levels of alkalinity, hardness, total dissolved solids, pH, HCO3-, Na+, and Ca2+ than the national standards and the WHO guidelines. However, the deviations from standards for all the above parameters were not statistically significant (one-sample t-test, P>0.05). Conversely, in some of the brands, some of the essential elements like Ca2+, K+, Mg2+, and F- were found at very low concentrations. The rest of the parameters, including CO3(2-), SO4(2-), PO4(3-) (orthophosphates), Cl-, F-, NO3-, NO2-, K+, Mg2+, Fe, Mn, Cr, Cd, Cu, Ni, and Pb were within the acceptable ranges in all the brands. Bottled water brands containing very high concentrations of dissolved substances may pose health risks for individuals living with heart and kidney related problems. On the other hand, brands having chemicals lower than the optimum level may also harm the health of consumers who choose those brands as a sole source of drinking water. Thus, we suggest those responsible authorities to ensure regular monitoring and testing for chemical compositions of bottled water.

Detection of antistripping additives with quick bottle test.

DOT National Transportation Integrated Search

1980-01-01

Several variations of the quick bottle test were evaluated to determine the procedure having the best repeatability. Naphtha was selected over kerosene and white gas as the solvent for use in the test, and room temperature was selected over 140F as...

Regulation and Education: Strategies for Solving the Bottle Feeding Problem. Monograph Series No. 4.

ERIC Educational Resources Information Center

Greiner, Ted

This book is the fourth monograph in the Cornell International Monograph Series, the second in the series to deal with the question of breast versus bottle feeding. The introduction to the monograph discusses the shift from breast to bottle feeding in both industrialized and developing nations. Some of the reasons for, and consequences of, the…

Influence of yeast strain, priming solution and temperature on beer bottle conditioning.

PubMed

Marconi, Ombretta; Rossi, Serena; Galgano, Fernanda; Sileoni, Valeria; Perretti, Giuseppe

2016-09-01

Recently, there has been a significant increase in the number of microbreweries. Usually, craft beers are bottle conditioned; however, few studies have investigated beer refermentation. One of the objectives of this study was to evaluate the impacts of different experimental conditions, specifically yeast strain, priming solution and temperature, on the standard quality attributes, the volatile compounds and the sensory profile of the bottle-conditioned beer. The other aim was to monitor the evolution of volatile compounds and amino acids consumption throughout the refermentation process to check if it is possible to reduce the time necessary for bottle conditioning. The results indicate that the volatile profile was mainly influenced by the strain of yeast, and this may have obscured the possible impacts of the other parameters. Our results also confirm that the two yeast strains showed different metabolic activity, particularly with respect to esters production. Moreover, we found the Safbrew S-33® strain when primed with Siromix® and refermented at 30 °C yielded the fastest formation of higher alcohols while maintaining low production of off-flavours. These results suggest a formulation that may reduce the time needed for bottle conditioning without affecting the quality of the final beer which may simultaneously improve efficiency and economic profits. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Impact of bottled water storage duration and location on bacteriological quality.

PubMed

Duranceau, Steven J; Emerson, Hilary P; Wilder, Rebecca J

2012-01-01

An investigation studying the effects of storage duration and location on the persistence of heterotrophic microorganisms in oligotrophic bottled water environments has been completed. One-gallon high-density polyethylene water containers stored for up to 16 weeks at temperatures ranging from 2°C to >49°C in a refrigerator, indoor cabinet, covered porch, and car trunk were evaluated for microbiological quality. Heterotrophic plate counts (HPCs) of up to 4 × 10(3) cfu/mL were detected in containers stored on a porch and car trunk; whereas, HPCs were found not to exceed 400 cfu/mL and 100 cfu/mL for bottles stored in indoor cabinets and refrigerators, respectively. Containers stored on an enclosed porch for up to seven years contained HPC of up to 4 × 10(4) cfu/mL. Logistic and Gompertz growth models predicted microbial growth rates for bottled water stored on a protected porch environment for long (R(2) 0.99) and short-term (R(2) 0.86) durations.

40 CFR 141.101 - Use of bottled water.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 23 2011-07-01 2011-07-01 false Use of bottled water. 141.101 Section 141.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Use of Non-Centralized Treatment Devices § 141.101...

40 CFR 141.101 - Use of bottled water.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Use of bottled water. 141.101 Section 141.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Use of Non-Centralized Treatment Devices § 141.101...

40 CFR 141.101 - Use of bottled water.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 23 2014-07-01 2014-07-01 false Use of bottled water. 141.101 Section 141.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Use of Non-Centralized Treatment Devices § 141.101...

40 CFR 141.101 - Use of bottled water.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 24 2013-07-01 2013-07-01 false Use of bottled water. 141.101 Section 141.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Use of Non-Centralized Treatment Devices § 141.101...

40 CFR 141.101 - Use of bottled water.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 24 2012-07-01 2012-07-01 false Use of bottled water. 141.101 Section 141.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Use of Non-Centralized Treatment Devices § 141.101...

Physicochemical and bacteriological quality of bottled drinking water in three sites of Amhara Regional State, Ethiopia.

PubMed

Biadglegne, Fantahun; Tessema, Belay; Kibret, Mulugeta; Abera, Bayeh; Huruy, Kahsay; Anagaw, Belay; Mulu, Andargachew

2009-10-01

The consumption of bottled drinking water is becoming increasing in Ethiopia. As a result there has been a growing concern about the chemical, physical and bacteriological quality of this product. Studies on the chemical, physical and bacteriological quality of bottled water is quite scarce in Ethiopia. This study was therefore aimed to assess the physicochemical and bacteriological qualities of three factories of bottled drinking water products produced in Amhara region. A Laboratory based comparative study was conducted to evaluate the physicochemical and bacteriological quality of three factories of bottled drinking water produced in Amhara region. Analysis on the quality of bottled drinking water from the sources, wholesalers and retailers were made with World Health Organization and Quality and Standards Authority of Ethiopia recommendations. Triplicate samples from three types of bottled drinking water were randomly collected and analyzed from June, 2006 to December, 2006. A total of 108 commercial bottled drinking water samples were analyzed. The result showed that except pH of factory A all the physicochemical parameters analyzed were with in the recommended limits. The pH value of factory A tested from sources is 5.3 and from wholesalers and retailers is 5.5 and 5.3, respectively, which is below the normal value set by World Health Organization (6.5-8.0) and Quality and Standards Authority of Ethiopia (6.0-8.5). Our analyses also demonstrated that 2 (16.7%) of the samples tested from sources and 1 (8.3%) from wholesalers of factory B were contaminated with total coliforms, where as 2 (16.7%) samples from retailers were also contaminated with total coliforms. On the other hand, 1 (8.3%) of the samples tested from wholesalers and 2 (16.7%) of the samples tested from retailers of factory A were also contaminated with total coliforms. Total coliforms were not detected from all samples of factory C, fecal coliforms were not also isolated from all samples

Effect of Fill Temperature on Clostridium botulinum Type A Toxin Activity during the Hot Filling of Juice Bottles.

PubMed

Skinner, Guy E; Fleischman, Gregory J; Balster, Fran; Reineke, Karl; Reddy, N Rukma; Larkin, John W

2015-08-01

The potential threat of terrorist attacks against the United States food supply using neurotoxin produced by Clostridium botulinum (BoNT) has resulted in the need for studying the effect of various food process operations on the bioavailability of this toxin. The objective of this study was to evaluate C. botulinum type A neurotoxin bioavailability after a simulated hot fill juice bottling operation. C. botulinum type A acid mud toxin (∼10(6) mouse lethal dose [MLD50]/ml) was deposited into juice bottles at an experimentally determined fastest cooling spot. Bottles (12 or 20 oz [355 and 592 ml]) were filled with either apple juice or an orange drink, at 80 or 85°C, in either upright or inverted orientations. Toxicity of the juice was evaluated as a function of holding time (1 to 2 min) by the mouse bioassay. The fastest cooling point in the upright orientation was determined to be at a bottle's bottom rim. In the inverted orientation, the fastest cooling point was in the bottle cap region. With respect to these two points, the upright bottle cooled faster than the inverted bottle, which was reflected in a higher inactivation of BoNT in the latter. For the orange drink (pH 2.9) toxicity was reduced by 0.5 × 10(6) MLD50/ml to a nondetectable level after 1 min in all bottle sizes, orientations, and temperatures as measured by the mouse bioassay. This indicates that there was at least a 0.5 × 10(6) MLD50/ml reduction in activity. Inactivation in apple juice (pH 4.0), to the same degree as in the orange drink, was found only for the inverted orientation at 85°C. Complete inactivation in apple juice for all conditions was found at a lower added toxin level of 0.25 × 10(5) MLD50/ml. In general, bottle inversion and filling at 85°C provided complete inactivation of BoNT to the 0.5 × 10(6) MLD50/ml level. All experiments resulted in the inactivation of 2.5 × 10(4) MLD50/ml of BoNT regardless of juice type, fill temperature, or bottle orientation and size.

Screening of hormone-like activities in bottled waters available in Southern Spain using receptor-specific bioassays.

PubMed

Real, Macarena; Molina-Molina, José-Manuel; Jiménez-Díaz, Inmaculada; Arrebola, Juan Pedro; Sáenz, José-María; Fernández, Mariana F; Olea, Nicolás

2015-01-01

Bottled water consumption is a putative source of human exposure to endocrine-disrupting chemicals (EDCs). Research has been conducted on the presence of chemicals with estrogen-like activity in bottled waters and on their estrogenicity, but few data are available on the presence of hormonal activities associated with other nuclear receptors (NRs). The aim of this study was to determine the presence of endocrine activities dependent on the activation of human estrogen receptor alpha (hERa) and/or androgen receptor (hAR) in water in glass or plastic bottles sold to consumers in Southern Spain. Hormone-like activities were evaluated in 29 bottled waters using receptor-specific bioassays based on reporter gene expression in PALM cells [(anti-)androgenicity] and cell proliferation assessment in MCF-7 cells [(anti-)estrogenicity] after optimized solid phase extraction (SPE). All of the water samples analyzed showed hormonal activity. This was estrogenic in 79.3% and anti-estrogenic in 37.9% of samples and was androgenic in 27.5% and anti-androgenic in 41.3%, with mean concentrations per liter of 0.113pM 17β-estradiol (E2) equivalent units (E2Eq), 11.01pM anti-estrogen (ICI 182780) equivalent units (ICI 182780Eq), 0.33pM methyltrienolone (R1881) equivalent units (R1881Eq), and 0.18nM procymidone equivalent units (ProcEq). Bottled water consumption contributes to EDC exposure. Hormone-like activities observed in waters from both plastic and glass bottles suggest that plastic packaging is not the sole source of contamination and that the source of the water and bottling process may play a role, among other factors. Further research is warranted on the cumulative effects of long-term exposure to low doses of EDCs. Copyright © 2014 Elsevier Ltd. All rights reserved.

Preference for tap, bottled, and recycled water: Relations to PTC taste sensitivity and personality.

PubMed

Harmon, Daniel; Gauvain, Mary; Z Reisz; Arthur, Isaac; Story, S Drew

2018-02-01

This study investigated people's preferences for different water sources and factors that predict such preferences using a blind taste test. Water preferences of 143 participants for one name-brand bottled water, one groundwater-sourced tap water, and one indirect potable reuse (IDR) water were assessed. For predictors of water preference, we measured each participant's PTC taste sensitivity and assessed two personality traits (Neuroticism, Openness to Experience). We also explored participants' descriptions of each water source. Results indicate a preference for water treated with Reverse Osmosis (RO) (bottled and IDR water) over groundwater-sourced water, which had higher pH levels and lower concentrations of Ca and HCO 3 - . PTC taste sensitivity did not predict preferences, while Openness to Experience and Neuroticism predicted preference for IDR water. Positive relations between Openness to Experience and preferences for bottled and IDR water were moderated by gender and were stronger among females. Participants described water primarily by its taste and texture. Findings suggest that (1) tap water treated by RO is equally preferable to some bottled water, (2) personality traits may affect water preferences, and (3) prior findings of gender differences in preferences for bottled water may reflect personality characteristics. Efforts to increase acceptance for sustainable water alternatives, such as IDR, may be more successful by assuring consumers about taste and addressing personality traits that encourage or inhibit use. Copyright © 2017 Elsevier Ltd. All rights reserved.

Presence of polychlorinated biphenyls (PCBs) in bottled drinking water in Mexico City.

PubMed

Salinas, Rutilio Ortiz; Bermudez, Beatriz Schettino; Tolentino, Rey Gutiérrez; Gonzalez, Gilberto Díaz; Vega y León, Salvador

2010-10-01

This paper describes the concentrations of seven polychlorinated biphenyls (PCBs) in bottled drinking water samples that were collected over 1 year from Mexico City in two sizes (1.5 and 19 L), using gas chromatography with an electron capture detector. PCBs 28 (0.018-0.042 μg/L), 52 (0.006-0.015 μg/L) and 101 (0.001-0.039 μg/L) were the most commonly found and were present in the majority of the samples. However, total concentrations of PCBs in bottled drinking water (0.035-0.039 μg/L) were below the maximum permissible level of 0.50 μg/L stated in Mexican regulations and probably do not represent a hazard to human health. PCBs were detectable in all samples and we recommend a monitoring program be established to better understand the quality of drinking bottled water over time; this may help in producing solutions for reducing the presence of organic contaminants.

Vector-virus interactions and transmission dynamics of West Nile virus.

PubMed

Ciota, Alexander T; Kramer, Laura D

2013-12-09

West Nile virus (WNV; Flavivirus; Flaviviridae) is the cause of the most widespread arthropod-borne viral disease in the world and the largest outbreak of neuroinvasive disease ever observed. Mosquito-borne outbreaks are influenced by intrinsic (e.g., vector and viral genetics, vector and host competence, vector life-history traits) and extrinsic (e.g., temperature, rainfall, human land use) factors that affect virus activity and mosquito biology in complex ways. The concept of vectorial capacity integrates these factors to address interactions of the virus with the arthropod host, leading to a clearer understanding of their complex interrelationships, how they affect transmission of vector-borne disease, and how they impact human health. Vertebrate factors including host competence, population dynamics, and immune status also affect transmission dynamics. The complexity of these interactions are further exacerbated by the fact that not only can divergent hosts differentially alter the virus, but the virus also can affect both vertebrate and invertebrate hosts in ways that significantly alter patterns of virus transmission. This chapter concentrates on selected components of the virus-vector-vertebrate interrelationship, focusing specifically on how interactions between vector, virus, and environment shape the patterns and intensity of WNV transmission.

Vector-Virus Interactions and Transmission Dynamics of West Nile Virus

PubMed Central

Ciota, Alexander T.; Kramer, Laura D.

2013-01-01

West Nile virus (WNV; Flavivirus; Flaviviridae) is the cause of the most widespread arthropod-borne viral disease in the world and the largest outbreak of neuroinvasive disease ever observed. Mosquito-borne outbreaks are influenced by intrinsic (e.g., vector and viral genetics, vector and host competence, vector life-history traits) and extrinsic (e.g., temperature, rainfall, human land use) factors that affect virus activity and mosquito biology in complex ways. The concept of vectorial capacity integrates these factors to address interactions of the virus with the arthropod host, leading to a clearer understanding of their complex interrelationships, how they affect transmission of vector-borne disease, and how they impact human health. Vertebrate factors including host competence, population dynamics, and immune status also affect transmission dynamics. The complexity of these interactions are further exacerbated by the fact that not only can divergent hosts differentially alter the virus, but the virus also can affect both vertebrate and invertebrate hosts in ways that significantly alter patterns of virus transmission. This chapter concentrates on selected components of the virus-vector-vertebrate interrelationship, focusing specifically on how interactions between vector, virus, and environment shape the patterns and intensity of WNV transmission. PMID:24351794

Raman and AFM study of gamma irradiated plastic bottle sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ali, Yasir; Kumar, Vijay; Dhaliwal, A. S.

2013-02-05

In this investigation, the effects of gamma irradiation on the structural properties of plastic bottle sheet are studied. The Plastic sheets were exposed with 1.25MeV {sup 60}Co gamma rays source at various dose levels within the range from 0-670 kGy. The induced modifications were followed by micro-Raman and atomic force microscopy (AFM). The Raman spectrum shows the decrease in Raman intensity and formation of unsaturated bonds with an increase in the gamma dose. AFM image displays rough surface morphology after irradiation. The detailed Raman analysis of plastic bottle sheets is presented here, and the results are correlated with the AFMmore » observations.« less

Chemical, microbial and physical evaluation of commercial bottled waters in greater Houston area of Texas.

PubMed

Saleh, Mahmoud A; Abdel-Rahman, Fawzia H; Woodard, Brooke B; Clark, Shavon; Wallace, Cecil; Aboaba, Adetoun; Zhang, Wenluo; Nance, James H

2008-03-01

Due to the increased demand and consumption of bottled water in the United States, there has been a growing concern about the quality of this product. Retail outlets sell local as well as imported bottled water to consumers. Three bottles for each of 35 different brands of bottled water were randomly collected from local grocery stores in the greater Houston area. Out of the 35 different brands, 16 were designated as spring water, 11 were purified and/or fortified tap water, 5 were carbonated water and 3 were distilled water. Chemical, microbial and physical properties of all samples were evaluated including pH, conductivity, bacteria counts, anion concentration, trace metal concentration, heavy metal and volatile organics concentration were determined in all samples. Inductively coupled plasma/mass spectrometry (ICPMS) was used for elemental analysis, gas chromatography with electron capture detector (GCECD) as well as gas chromatography mass spectrometry (GCMS) were used for analysis of volatile organics, ion chromatography (IC) and selective ion electrodes were used for the analysis of anions. Bacterial identification was performed using the Biolog software (Biolog, Inc., Hayward, Ca, USA). The results obtained were compared with guidelines of drinking water recommended by the International Bottled Water Association (IBWA), United States Food and Drug Administration (FDA), United States Environmental Protection Agency (EPA) and the World Health Organization (WHO) drinking water standard. The majority of the analyzed chemicals were below their respective drinking water standards for maximum admissible concentrations (MAC). Volatile organic chemicals were found to be below detection limits. Four of the 35 brands of the bottled water samples analyzed were found to be contaminated with bacteria.

Use of lectins to in situ visualize glycoconjugates of extracellular polymeric substances in acidophilic archaeal biofilms

PubMed Central

Zhang, R Y; Neu, T R; Bellenberg, S; Kuhlicke, U; Sand, W; Vera, M

2015-01-01

Biofilm formation and the production of extracellular polymeric substances (EPS) by meso- and thermoacidophilic metal-oxidizing archaea on relevant substrates have been studied to a limited extent. In order to investigate glycoconjugates, a major part of the EPS, during biofilm formation/bioleaching by archaea on pyrite, a screening with 75 commercially available lectins by fluorescence lectin-binding analysis (FLBA) has been performed. Three representative archaeal species, Ferroplasma acidiphilum DSM 28986, Sulfolobus metallicus DSM 6482T and a novel isolate Acidianus sp. DSM 29099 were used. In addition, Acidianus sp. DSM 29099 biofilms on elemental sulfur were studied. The results of FLBA indicate (i) 22 lectins bound to archaeal biofilms on pyrite and 21 lectins were binding to Acidianus sp. DSM 29099 biofilms on elemental sulfur; (ii) major binding patterns, e.g. tightly bound EPS and loosely bound EPS, were detected on both substrates; (iii) the three archaeal species produced various EPS glycoconjugates on pyrite surfaces. Additionally, the substratum induced different EPS glycoconjugates and biofilm structures of cells of Acidianus sp. DSM 29099. Our data provide new insights into interactions between acidophilic archaea on relevant surfaces and also indicate that FLBA is a valuable tool for in situ investigations on archaeal biofilms. PMID:25488256

Gourds: Bitter, Bottle, Wax, Snake, Sponge and Ridge

USDA-ARS?s Scientific Manuscript database

Minor cucurbits include bitter gourd, bottle gourd, wax gourd, snake gourd, and sponge and ridge gourd, which are significant dietary sources of nutrients such as vitamin A and C, iron and calcium. These cucurbits are cultivated and marketed by smallholder farmers and remain important components of ...

The Blue Bottle Experiment--Simple Demonstration of Self-Organization.

ERIC Educational Resources Information Center

Adamcikova, L'ubica; Sevcik, Peter

1998-01-01

Explains a way of observing pattern formation in the Blue Bottle chemistry demonstration by pouring a solution containing sodium hydroxide, glucose, and dye into a Petri dish and placing the dish on an overhead projector. (WRM)

MALDI-TOF mass spectrometry for early identification of bacteria grown in blood culture bottles.

PubMed

Zabbe, Jean-Benoît; Zanardo, Laura; Mégraud, Francis; Bessède, Emilie

2015-08-01

This note reports an interesting way to rapidly identify bacteria grown from blood culture bottles. Chocolate agar plates were inoculated with 1 drop of the positive blood bottle medium. After a 3-hour incubation, the growth veil was submitted to MALDI-TOF mass spectrometry: 77% of the bacteria present have been correctly identified. Copyright © 2015 Elsevier B.V. All rights reserved.

Clinical Significance of the Champagne Bottle Neck Sign in the Extracranial Carotid Arteries of Patients with Moyamoya Disease.

PubMed

Yasuda, C; Arakawa, S; Shimogawa, T; Kanazawa, Y; Sayama, T; Haga, S; Morioka, T

2016-05-26

The champagne bottle neck sign represents a rapid reduction in the extracranial ICA diameters and is a characteristic feature of Moyamoya disease. However, the clinical significance of the champagne bottle neck sign is unclear. We investigated the relationship between the champagne bottle neck sign and the clinical and hemodynamic stages of Moyamoya disease. We analyzed 14 patients with Moyamoya disease before revascularization (5 men, 9 women; age, 43.2 ± 19.3 years). The ratio of the extracranial ICA and common carotid artery diameters was determined using carotid ultrasonography or cerebral angiography; a ratio of < 0.5 was considered champagne bottle neck sign-positive. The clinical disease stage was determined using the Suzuki angiographic grading system. CBF and cerebral vasoreactivity also were measured. The ICA/common carotid artery ratio (expressed as median [interquartile range]) decreased as the clinical stage advanced (stages I-II, 0.71 [0.60-0.77]; stages III-IV, 0.49 [0.45-0.57]; stages V-VI, 0.38 [0.34-0.47]; P < .001). Lower ICA/common carotid artery ratio tended to occur in symptomatic versus asymptomatic arteries (0.47 [0.40-0.53] versus 0.57 [0.40-0.66], respectively; P = .06). Although the ICA/common carotid artery ratio was not related to cerebral perfusion, it decreased as cerebral vasoreactivity decreased (P < .01). All champagne bottle neck sign-positive arteries were classified as Suzuki stage ≥III, 73% were symptomatic, and 89% exhibited reduced cerebral vasoreactivity. In contrast, all champagne bottle neck sign-negative arteries were Suzuki stage ≤III, 67% were asymptomatic, and all showed preserved cerebral vasoreactivity. The champagne bottle neck sign was related to advanced clinical stage, clinical symptoms, and impaired cerebral vasoreactivity. Thus, detection of the champagne bottle neck sign might be useful in determining the clinical and hemodynamic stages of Moyamoya disease. © 2016 American Society of Neuroradiology.

Comparative evolution of oxygen, carbon dioxide, nitrogen, and sulfites during storage of a rosé wine bottled in PET and glass.

PubMed

Toussaint, Marie; Vidal, Jean-Claude; Salmon, Jean-Michel

2014-04-02

The management of dissolved and headspace gases during bottling and the choice of packaging are both key factors for the shelf life of wine. Two kinds of 75 cL polyethylene terephthalate (PET) bottles (with or without recycled PET) were compared to glass bottles filled with a rosé wine, closed with the same screwcaps and stored upright at 20 °C in light or in the dark. Analytical monitoring (aphrometric pressure, headspace volume, O2, N2, CO2, and SO2) was carried out for 372 days. After the consumption of O2 trapped during bottling, the total O2 content in glass bottles remained stable. A substantial decrease of CO2 and SO2 concentration and an increase of O2 concentration were observed in the PET bottles after 6 months because of the considerable gas permeability of monolayer PET. Light accelerated O2 consumption during the early months. Finally, the kinetic monitoring of partial pressures in gas and liquid phases in bottles showed contrasting behavior of O2 and N2 in comparison with CO2.

Comparison of BacT/Alert FAN and FAN Plus Bottles with Conventional Medium for Culturing Cerebrospinal Fluid.

PubMed

Yoo, In Young; Chun, Sejong; Song, Dong Joon; Huh, Hee Jae; Lee, Nam Yong

2016-11-01

We compared the BacT/Alert system FAN and FAN Plus media to conventional media for culturing cerebrospinal fluid (CSF) with 2,545 samples. FAN/FAN Plus bottles showed better performance for isolating microorganisms in CSF than conventional media (positive rate, 7.2% [182/2,545] versus 3.1% [80/2,545]). The incremental recovery rate of Cryptococcus neoformans from FAN Plus bottles was higher than that from FAN bottles. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Design and Operation of Equipment to Detect and Remove Water within Used Nuclear Fuel Storage Bottles

DOE Office of Scientific and Technical Information (OSTI.GOV)

C.C. Baker; T.M. Pfeiffer; J.C. Price

2013-09-01

Inspection and drying equipment has been implemented in a hot cell to address the inadvertent ingress of water into used nuclear fuel storage bottles. Operated with telemanipulators, the system holds up to two fuel bottles and allows their threaded openings to be connected to pressure transducers and a vacuum pump. A prescribed pressure rebound test is used to diagnose the presence of moisture. Bottles found to contain moisture are dried by vaporization. The drying process is accelerated by the application of heat and vacuum. These techniques detect and remove virtually all free water (even water contained in a debris bed)more » while leaving behind most, if not all, particulates. The extracted water vapour passes through a thermoelectric cooler where it is condensed back to the liquid phase for collection. Fuel bottles are verified to be dry by passing the pressure rebound test.« less

Putting Time in a Bottle--Or a Box!

ERIC Educational Resources Information Center

Turner, Thomas N.

1989-01-01

Discusses the problems of teaching time concepts to children. Suggests alternatives to the traditional time line. Describes the use of bottles and boxes as symbols of units of time when encouraging children to visualize and understand time. Provides information which will assist teachers in using these techniques. (KO)

A DFT investigation of the blue bottle experiment: E∘half-cell analysis of autoxidation catalysed by redox indicators.

PubMed

Limpanuparb, Taweetham; Roongruangsree, Pakpong; Areekul, Cherprang

2017-11-01

The blue bottle experiment is a collective term for autoxidation reactions catalysed by redox indicators. The reactions are characterized by their repeatable cycle of colour changes when shaken/left to stand and intricate chemical pattern formation. The blue bottle experiment is studied based on calculated solution-phase half-cell reduction potential of related reactions. Our investigation confirms that the reaction in various versions of the blue bottle experiment published to date is mainly the oxidation of an acyloin to a 1,2-dicarbonyl structure. In the light of the calculations, we also propose new non-acyloin reducing agents for the experiment. These results can help guide future experimental studies on the blue bottle experiment.

Fluoride content in bottled drinking waters, carbonated soft drinks and fruit juices in Davangere city, India.

PubMed

Thippeswamy, H M; Kumar, Nanditha; Anand, S R; Prashant, G M; Chandu, G N

2010-01-01

The regular ingestion of fluoride lowers the prevalence of dental caries. The total daily intake of fluoride for optimal dental health should be 0.05-0.07 mg fluoride/kg body weight and to avoid the risk of dental fluorosis, the daily intake should not exceed a daily level of 0.10 mg fluoride/kg body weight. The main source of fluoride is from drinking water and other beverages. As in other countries, consumption of bottled water, juices and carbonated beverages has increased in our country. To analyze the fluoride content in bottled water, juices and carbonated soft drinks that were commonly available in Davangere city. Three samples of 10 commercially available brands of bottled drinking water, 12 fruit juices and 12 carbonated soft drinks were purchased. Bottled water and carbonated soft drinks were stored at a cold place until fluoride analysis was performed and a clear juice was prepared using different fruits without the addition of water. Then, the fluoride analysis was performed. The mean and standard deviation of fluoride content of bottled water, fruit juices and carbonated soft drinks were measured, which were found to be 0.20 mg (±0.19) F/L, 0.29 mg (±0.06) F/L and 0.22 mg (±0.05) F/L, respectively. In viewing the results of the present study, it can be concluded that regulation of the optimal range of fluoride in bottled drinking water, carbonated soft drinks and fruit juices should be drawn for the Indian scenario.

Linear and Nonlinear Elasticity of Networks Made of Comb-like Polymers and Bottle-Brushes

NASA Astrophysics Data System (ADS)

Liang, H.; Dobrynin, A.; Everhart, M.; Daniel, W.; Vatankhah-Varnoosfaderani, M.; Sheiko, S.

We study mechanical properties of networks made of combs and bottle-brushes by computer simulations, theoretical calculations and experimental techniques. The networks are prepared by cross-linking backbones of combs or bottle-brushes with linear chains. This results in ``hybrid'' networks consisting of linear chains and strands of combs or bottle-brushes. In the framework of the phantom network model, the network modulus at small deformations G0 can be represented as a sum of contributions from linear chains, G0 , l, and strands of comb or bottle-brush, G0 , bb. If the length of extended backbone between crosslinks, Rmax, is much longer than the Kuhn length, bk, the modulus scales with the degree of polymerization of the side chains, nsc, and number of monomers between side chains, ng, as G0 , bb (nsc/ng + 1)-1. In the limit when bk becomes of the order of Rmax, the combs and bottle-brushes can be considered as semiflexible chains, resulting in a network modulus to be G0 , bb (nsc/ng + 1)-1(nsc2/2/ng) . In the nonlinear deformation regime, the strain-hardening behavior is described by the nonlinear network deformation model, which predicts that the true stress is a universal function of the structural modulus, G, first strain invariant, I1, and deformation ratio, β. The results of the computer simulations and predictions of the theoretical model are in a good agreement with experimental results. NSF DMR-1409710, DMR-1407645, DMR-1624569, DMR-1436201.

Optimization of fixed titanium dioxide film on PET bottles and visual indicator for water disinfection

NASA Astrophysics Data System (ADS)

Heredia-Munoz, Manuel Antonio

Water is perhaps the most important resource that sustains human life. According to the World Health Organization (WHO), almost two billion people do not have access to the required water that is needed to satisfy their daily needs and one billion do not have access to clean sources of water for consumption, most of them living in isolated and poor areas around the globe. Poor quality water increases the risk of cholera, typhoid fever and dysentery, and other water-borne illness making this problem a real crisis that humankind is facing. Several water disinfection technologies have been proposed as solutions for this problem. Solar water disinfection using TiO2 coated PET bottles was the alternative that is studied in this work. This technology does not only inactivate bacteria but also disintegrates organic chemicals that can be present in water. The objectives of this work address the optimization of the TiO 2 coated PET bottles technologies. The improvement on the bottle coating process, using two coats of 10% W/V of TiO2 in a solution of vinegar and sodium bicarbonate to form the TiO2 film, the use of a different indigo carmine (1.25 X 10-1mg/pill) concentration in the pill indicator of contamination, the increase of the disinfection rate through shaking the bottles, degradation under intermittent UV radiation and the effect of bottle size on photocatalytic water disinfection were among the most important findings. A new mathematical model that describes better photocatalytic water disinfection in TiO2 coated bottles and simulates water disinfection under different working conditions was another important achievement. These results can now be used to design a strategy for disseminating this technology in areas where it is required and, in that way, generate the greatest positive impact on the people needing safe drinking water.

Feeding bottles usage and the prevalence of childhood allergy and asthma.

PubMed

Hsu, Nai-Yun; Wu, Pei-Chih; Bornehag, Carl-Gustaf; Sundell, Jan; Su, Huey-Jen

2012-01-01

This study aimed to examine the association between the length of use of feeding bottles or pacifiers during childhood and the prevalence of respiratory and allergic morbidities. A large-scale questionnaire survey was performed in day care centers and kindergartens (with children's ages ranging from 2 to 7 years) in southern Taiwan, and a total of 14,862 questionnaires completed by parents were finally recruited for data analysis. Effects of using feeding bottles on children's wheezing/asthma (adjusted OR: 1.05, 95% CI 1.00-1.09), allergic rhinitis (adjusted OR: 1.04, 95% CI 1.00-1.08), and eczema (adjusted OR: 1.07, 95% CI 1.01-1.2) were found. Moreover, significant dose-dependent relationships were further established after an adjustment for confounders was performed that included children's ages, gender, gestational age, birth weight, length of breastfeeding, the age when first given infant formula or complementary foods, family history, parental educational levels, and smoking status, as well as the problem of indoor water damage. This study was the first to reveal the potential risk of using plastic consumer products such as feeding bottles on the reported health status of preschool children in Asian countries.

27 CFR 4.38a - Bottle cartons, booklets and leaflets.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Labeling Requirements... written, printed, graphic, or other matter accompanying the bottle to the consumer buyer shall not contain...

Representing infant feeding: content analysis of British media portrayals of bottle feeding and breast feeding

PubMed Central

Henderson, Lesley; Kitzinger, Jenny; Green, Josephine

2000-01-01

Objective To examine how breast feeding and bottle feeding are represented by the British media. Design Content analysis. Subjects Television programmes and newspaper articles that made reference to infant feeding during March 1999. Setting UK mass media. Main outcome measures Visual and verbal references to breast or bottle feeding in newspapers and television programmes. Results Overall, 235 references to infant feeding were identified in the television sample and 38 in the newspaper sample. Bottle feeding was shown more often than breast feeding and was presented as less problematic. Bottle feeding was associated with “ordinary” families whereas breast feeding was associated with middle class or celebrity women. The health risks of formula milk and the health benefits of breast feeding were rarely mentioned. Conclusions The media rarely present positive information on breast feeding, even though this feeding practice is associated with the most health benefits. Health professionals and policy makers should be aware of patterns in media coverage and the cultural background within which women make decisions about infant feeding. PMID:11073512

Avoidance of bottles during the establishment of breast feeds in preterm infants.

PubMed

Collins, Carmel T; Gillis, Jennifer; McPhee, Andrew J; Suganuma, Hiroki; Makrides, Maria

2016-10-19

Preterm infants start milk feeds by gavage tube. As they mature, sucking feeds are gradually introduced. Women who choose to breast feed their preterm infant are not always able to be in hospital with their baby and need an alternative approach to feeding. Most commonly, milk (expressed breast milk or formula) is given by bottle. Whether using bottles during establishment of breast feeds is detrimental to breast feeding success is a topic of ongoing debate. To identify the effects of avoidance of bottle feeds during establishment of breast feeding on the likelihood of successful breast feeding, and to assess the safety of alternatives to bottle feeds. We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 2), MEDLINE via PubMed (1966 to July 2016), Embase (1980 to July 2016) and CINAHL (1982 to July 2016). We also searched databases of clinical trials and the reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. Randomised and quasi-randomised controlled trials comparing avoidance of bottles with use of bottles in women who have chosen to breast feed their preterm infant. Two review authors independently assessed trial quality and extracted data. When appropriate, we contacted study authors for additional information. Review authors used standard methods of The Cochrane Collaboration and the Cochrane Neonatal Review Group. We included seven trials with 1152 preterm infants. Five studies used a cup feeding strategy, one used a tube feeding strategy and one used a novel teat when supplements to breast feeds were needed. We included the novel teat study in this review, as the teat was designed to more closely mimic the sucking action of breast feeding. The trials were of small to moderate size, and two had high risk of attrition bias. Adherence with cup feeding was poor in one of the studies, indicating dissatisfaction

Molecular and Macromolecular Changes in Bottle-Aged White Wines Reflect Oxidative Evolution–Impact of Must Clarification and Bottle Closure

PubMed Central

Coelho, Christian; Julien, Perrine; Nikolantonaki, Maria; Noret, Laurence; Magne, Mathilde; Ballester, Jordi; Gougeon, Régis D.

2018-01-01

Chardonnay wines from Burgundy, obtained from musts with three levels of clarification (Low, Medium and High) during two consecutive vintages (2009 and 2010) and for two kinds of closures (screw caps and synthetic coextruded closures) were analyzed chemically and sensorially. Three bottles per turbidity level were opened in 2015 in order to assess the intensity of the reductive and/or oxidative aromas (REDOX sensory scores) by a trained sensory panel. The chemical analyses consisted in polyphenols and colloids quantification, followed by a proteomic characterization. For the two vintages, the REDOX sensory scores appeared to be driven both by the type of closure and to a lesser extent by the level of must clarification. Vintages and must racking prefermentative operations were also distinguished by chemical analyses. All white wines from the lowest must turbidity had the lowest REDOX sensory scores. Such wines exhibited lower concentrations in tyrosol and grape reaction product and higher concentrations in colloids with relatively low molecular weights. Among these macromolecules, grape proteins were also quantified, two of them exhibiting concentrations in bottled wines, which were statistically correlated to oxidative evolution in white wines. PMID:29682498

Study on heat transfer coefficients during cooling of PET bottles for food beverages

NASA Astrophysics Data System (ADS)

Liga, Antonio; Montesanto, Salvatore; Mannella, Gianluca A.; La Carrubba, Vincenzo; Brucato, Valerio; Cammalleri, Marco

2016-08-01

The heat transfer properties of different cooling systems dealing with Poly-Ethylene-Terephthalate (PET) bottles were investigated. The heat transfer coefficient (Ug) was measured in various fluid dynamic conditions. Cooling media were either air or water. It was shown that heat transfer coefficients are strongly affected by fluid dynamics conditions, and range from 10 W/m2 K to nearly 400 W/m2 K. PET bottle thickness effect on Ug was shown to become relevant under faster fluid dynamics regimes.

[India: breast feeding is obsolete, the bottle is modern].

PubMed

Uniyal, M

1992-09-07

In July, 1992 Indian health groups met in New Delhi to demand that the government promote a child nutrition code based on the 1981 code of the WHO which stated that mother's milk is quite sufficient and is the best nourishment for infants. Every day approximately 40,000 children are born in India, but thousands of them die in infancy because of infection caused by the unsanitary mixing of milk powder in unsterile bottles. Indian health activists want the government to regulate the production, access, and distribution of mother's milk substitutes, bottles, and child nutriments. A new law based on internationally recognized codes for marketing mother's milk substitutes could put an end to the present irresponsible marketing. Activists are not opposed to the production of milk powder, but they think it should only be used when the mother has no milk. The turnover of India's child nutrition industry is about $280 million per year with an annual increase of 5%. The use of bottle feeding has infiltrated the whole urban scene, and it is spreading in rural areas. Women consider bottle feeding a modern way of child feeding. 60 million kg of milk powder is produced yearly and sold under 25 different product names. Amul and Nestle command 85% of the growing market. Experts have calculated that 1 billion liters of mother's milk is wasted and replaced by substitute milk every year. Many Indian children get their first substitute milk at health posts where free or subsidized milk is distributed despite notices calling on mothers to breast-feed. According to a national survey sponsored by UNICEF, almost 1/2 of India's mothers give their children milk substitutes at the instigation of doctors or health personnel. 63% of children in the state of West Bengal were undernourished because families did not buy enough milk powder. The activists want the government to launch an offensive against the advertisement of breast milk substitutes in state-owned TV and radio and to promote proper

An Experimental Approach to Study Individual Differences in Infants' Intake and Satiation Behaviors during Bottle-Feeding.

PubMed

Ventura, Alison K; Mennella, Julie A

2017-02-01

As a group, bottle-fed infants are at higher risk for rapid weight gain compared with breast-fed infants. However, little is known about individual differences in feeding behaviors of bottle-feeding infants, as well as maternal and infant characteristics associated with bottle-feeding outcomes. We conducted a 2-day, within-subject study of 21 formula-feeding dyads; the within-subject factor was feeding condition: mother-led (ML; mothers were given the instruction to feed their infants as they typically would) vs. infant-led (IL; the experimenter ensured feeding began when infants signaled hunger and ended when they rejected the bottle on three consecutive occasions). Intake was determined by bottle weight; feedings were video-recorded and later analyzed to determine feeding duration and types of satiation behaviors displayed. Percent difference scores were calculated for each outcome as [((ML - IL)/IL) × 100] to standardize differences among dyads. Mothers completed questionnaires of feeding styles and infant temperament. On average, infants consumed ∼42% more formula during the ML- than IL-condition (p = 0.03). However, notable variation existed in difference scores for intake (range = -52.8% to 268.9%; higher scores reflect greater intake during ML than IL). Stepwise regression illustrated that greater intakes during the ML-condition were predicted by the combination of: (1) higher infant age; (2) lower levels of infant rhythmicity and adaptability; (3) higher levels of infant positive mood; and (4) lower levels of maternal restrictive and responsive feeding styles. This objective, experimental approach illustrated that variation in bottle-feeding outcomes is associated with characteristics of both members of the dyad.

An Experimental Approach to Study Individual Differences in Infants' Intake and Satiation Behaviors during Bottle-Feeding

PubMed Central

Mennella, Julie A.

2017-01-01

Abstract Background: As a group, bottle-fed infants are at higher risk for rapid weight gain compared with breast-fed infants. However, little is known about individual differences in feeding behaviors of bottle-feeding infants, as well as maternal and infant characteristics associated with bottle-feeding outcomes. Methods: We conducted a 2-day, within-subject study of 21 formula-feeding dyads; the within-subject factor was feeding condition: mother-led (ML; mothers were given the instruction to feed their infants as they typically would) vs. infant-led (IL; the experimenter ensured feeding began when infants signaled hunger and ended when they rejected the bottle on three consecutive occasions). Intake was determined by bottle weight; feedings were video-recorded and later analyzed to determine feeding duration and types of satiation behaviors displayed. Percent difference scores were calculated for each outcome as [((ML – IL)/IL) × 100] to standardize differences among dyads. Mothers completed questionnaires of feeding styles and infant temperament. Results: On average, infants consumed ∼42% more formula during the ML- than IL-condition (p = 0.03). However, notable variation existed in difference scores for intake (range = −52.8% to 268.9%; higher scores reflect greater intake during ML than IL). Stepwise regression illustrated that greater intakes during the ML-condition were predicted by the combination of: (1) higher infant age; (2) lower levels of infant rhythmicity and adaptability; (3) higher levels of infant positive mood; and (4) lower levels of maternal restrictive and responsive feeding styles. Conclusions: This objective, experimental approach illustrated that variation in bottle-feeding outcomes is associated with characteristics of both members of the dyad. PMID:27788024

Exploring the Gas Chemistry of Old Submarine Technologies Using Plastic Bottles as Reaction Vessels and Models

ERIC Educational Resources Information Center

Horikoshi, Ryo; Takeiri, Fumitaka; Kobayashi, Yoji; Kageyama, Hiroshi

2016-01-01

We describe an activity that is suitable for high school students and makes use of plastic bottles. This activity allows students to familiarize themselves with gas chemistry by introducing technologies that were applied in old submarine systems. Plastic bottles, which are representative of submarines, are used as reaction vessels. Three simple…

Domain structure, GTP-hydrolyzing activity and 7S RNA binding of Acidianus ambivalens ffh-homologous protein suggest an SRP-like complex in archaea.

PubMed

Moll, R; Schmidtke, S; Schäfer, G

1999-01-01

In this study we provide, for the first time, experimental evidence that a protein homologous to bacterial Ffh is part of an SRP-like ribonucleoprotein complex in hyperthermophilic archaea. The gene encoding the Ffh homologue in the hyperthermophilic archaeote Acidianus ambivalens has been cloned and sequenced. Recombinant Ffh protein was expressed in E. coli and subjected to biochemical and functional studies. A. ambivalens Ffh encodes a 50.4-kDa protein that is structured by three distinct regions: the N-terminal hydrophilic N-region (N), the GTP/GDP-binding domain (G) and a C-terminal located C-domain (C). The A. ambivalens Ffh sequence shares 44-46% sequence similarity with Ffh of methanogenic archaea, 34-36% similarity with eukaryal SRP54 and 30-34% similarity with bacterial Ffh. A polyclonal antiserum raised against the first two domains of A. ambivalens Ffh reacts specifically with a single protein (apparent molecular mass: 46 kDa, termed p46) present in cytosolic and in plasmamembrane cell fractions of A. ambivalens. Recombinant Ffh has a melting point of tm = 89 degreesC. Its intrinsic GTPase activity obviously depends on neutral pH and low ionic strength with a preference for chloride and acetate salts. Highest rates of GTP hydrolysis have been achieved at 81 degreesC in presence of 0.1-1 mm Mg2+. GTP hydrolysis is significantly inhibited by high glycerol concentrations, and the GTP hydrolysis rate also markedly decreases by addition of detergents. The Km for GTP is 13.7 microm at 70 degreesC and GTP hydrolysis is strongly inhibited by GDP (Ki = 8 microm). A. ambivalens Ffh, which includes an RNA-binding motif in the C-terminal domain, is shown to bind specifically to 7S RNA of the related crenarchaeote Sulfolobus solfataricus. Comparative sequence analysis reveals the presence of typical signal sequences in plasma membrane as well as extracellular proteins of hyperthermophilic crenarchaea which strongly supposes recognition events by an Ffh containing

Feeding Bottles Usage and the Prevalence of Childhood Allergy and Asthma

PubMed Central

Hsu, Nai-Yun; Wu, Pei-Chih; Bornehag, Carl-Gustaf; Sundell, Jan; Su, Huey-Jen

2012-01-01

This study aimed to examine the association between the length of use of feeding bottles or pacifiers during childhood and the prevalence of respiratory and allergic morbidities. A large-scale questionnaire survey was performed in day care centers and kindergartens (with children's ages ranging from 2 to 7 years) in southern Taiwan, and a total of 14,862 questionnaires completed by parents were finally recruited for data analysis. Effects of using feeding bottles on children's wheezing/asthma (adjusted OR: 1.05, 95% CI 1.00–1.09), allergic rhinitis (adjusted OR: 1.04, 95% CI 1.00–1.08), and eczema (adjusted OR: 1.07, 95% CI 1.01–1.2) were found. Moreover, significant dose-dependent relationships were further established after an adjustment for confounders was performed that included children's ages, gender, gestational age, birth weight, length of breastfeeding, the age when first given infant formula or complementary foods, family history, parental educational levels, and smoking status, as well as the problem of indoor water damage. This study was the first to reveal the potential risk of using plastic consumer products such as feeding bottles on the reported health status of preschool children in Asian countries. PMID:22291844

Prediction of ethanol in bottled Chinese rice wine by NIR spectroscopy

NASA Astrophysics Data System (ADS)

Ying, Yibin; Yu, Haiyan; Pan, Xingxiang; Lin, Tao

2006-10-01

To evaluate the applicability of non-invasive visible and near infrared (VIS-NIR) spectroscopy for determining ethanol concentration of Chinese rice wine in square brown glass bottle, transmission spectra of 100 bottled Chinese rice wine samples were collected in the spectral range of 350-1200 nm. Statistical equations were established between the reference data and VIS-NIR spectra by partial least squares (PLS) regression method. Performance of three kinds of mathematical treatment of spectra (original spectra, first derivative spectra and second derivative spectra) were also discussed. The PLS models of original spectra turned out better results, with higher correlation coefficient in calibration (R cal) of 0.89, lower root mean standard error of calibration (RMSEC) of 0.165, and lower root mean standard error of cross validation (RMSECV) of 0.179. Using original spectra, PLS models for ethanol concentration prediction were developed. The R cal and the correlation coefficient in validation (R val) were 0.928 and 0.875, respectively; and the RMSEC and the root mean standard error of validation (RMSEP) were 0.135 (%, v v -1) and 0.177 (%, v v -1), respectively. The results demonstrated that VIS-NIR spectroscopy could be used to predict ethanol concentration in bottled Chinese rice wine.

27 CFR 19.638 - Disposition of stocks of liquor bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... stocks of such bottles on hand shall either be disposed of to another person authorized to receive liquor.... However, on approval of a written application by the appropriate TTB officer of the region in which the...

Stability of micafungin sodium solutions at different concentrations in glass bottles and syringes.

PubMed

Briot, Thomas; Vrignaud, Sandy; Lagarce, Frédéric

2015-08-15

Micafungin is a costly treatment and packaging of 50 mg or 100 mg bottles only are available, while doses lower than 5 mg and 20 mg are often necessary in neonates and paediatrics patients, respectively. The stability of micafungin sodium in polypropylene syringes and glass bottles was studied at different concentrations. Solutions of micafungin diluted with NaCl 0.9% were prepared in glass bottles (20 and 10 mg/mL) or syringes (1 and 0.5 mg/mL) and stored at 25 °C, 60% humidity (RH), in the dark (ICH conditions). Solutions were also exposed to heat (70 °C) or alkaline solution (NaOH) in order to force degradation. Samples were analysed at days 1, 5, 8 (for bottles) and also 15 (for syringes) after the preparation and assayed in triplicate. Stability was studied using a stability-indicating high-performance liquid chromatographic method. Syringes stored at 25 °C retained over 90% of their initial concentration over the study period. Temperature and alkaline conditions had significant effect on the stability of micafungin, leading to apparition of degradation products. Moreover, sub visible particles were in the specification of the European Pharmacopeia along 15 days. To conclude, micafungin diluted in NaCl 0.9% and stored in polypropylene syringes was chemically stable for at least 15 days at 25 °C in the dark. Copyright © 2015 Elsevier B.V. All rights reserved.

A novel one-step synthesis for carbon-based nanomaterials from polyethylene terephthalate (PET) bottles waste.

PubMed

El Essawy, Noha A; Konsowa, Abdelaziz H; Elnouby, Mohamed; Farag, Hassan A

2017-03-01

Nowadays our planet suffers from an accumulation of plastic products that have the potential to cause great harm to the environment in the form of air, water, and land pollution. Plastic water bottles have become a great problem in the environment because of the large numbers consumed throughout the world. Certain types of plastic bottles can be recycled but most of them are not. This paper describes an economical solvent-free process that converts polyethylene terephthalate (PET) bottles waste into carbon nanostructure materials via thermal dissociation in a closed system under autogenic pressure together with additives and/or catalyst, which can act as cluster nuclei for carbon nanostructure materials such as fullerenes and carbon nanotubes. This research succeeded in producing and controlling the microstructure of various forms of carbon nanoparticles from the PET waste by optimizing the preparation parameters in terms of time, additives, and amounts of catalyst. Plastic water bottles are becoming a growing segment of the municipal solid waste stream in the world; some are recycled but many are left in landfill sites. Recycling PET bottles waste can positively impact the environment in several ways: for instance, reduced waste, resource conservation, energy conservation, reduced greenhouse gas emissions, and decreasing the amount of pollution in air and water sources. The main novelty of the present work is based on the acquisition of high-value carbon-based nanomaterials from PET waste by a simple solvent-free chemical technique. Thus, the prepared materials are considered to be promising, cheap, eco-friendly materials that may find use in different applications.

Portable NIR bottled liquid explosive detector

NASA Astrophysics Data System (ADS)

Itozaki, Hideo; Ono, Masaki; Ito, Shiori; Uekawa, Keisuke; Miyato, Yuji; Sato-Akaba, Hideo

2016-05-01

A near infrared bottled liquid scanner has been developed for security check at airports for anti-terrorism. A compact handheld liquid scanner has been developed using an LED as a light source, instead of a halogen lamp. An LED has much smaller size, longer life time and lower power consumption than those of the lamp. However, it has narrower wave band. Here, we tried to use LEDs to scan liquids and showed the possibility that LEDs can be used as a light source of liquid detector.

Evaluating the efficacy of biological and conventional insecticides with the new 'MCD bottle' bioassay.

PubMed

Sternberg, Eleanore D; Waite, Jessica L; Thomas, Matthew B

2014-12-16

Control of mosquitoes requires the ability to evaluate new insecticides and to monitor resistance to existing insecticides. Monitoring tools should be flexible and low cost so that they can be deployed in remote, resource poor areas. Ideally, a bioassay should be able to simulate transient contact between mosquitoes and insecticides, and it should allow for excito-repellency and avoidance behaviour in mosquitoes. Presented here is a new bioassay, which has been designed to meet these criteria. This bioassay was developed as part of the Mosquito Contamination Device (MCD) project and, therefore, is referred to as the MCD bottle bioassay. Presented here are two experiments that serve as a proof-of-concept for the MCD bottle bioassay. The experiments used four insecticide products, ranging from fast-acting, permethrin-treated, long-lasting insecticide nets (LLINs) that are already widely used for malaria vector control, to the slower acting entomopathogenic fungus, Beauveria bassiana, that is currently being evaluated as a prospective biological insecticide. The first experiment used the MCD bottle to test the effect of four different insecticides on Anopheles stephensi with a range of exposure times (1 minute, 3 minutes, 1 hour). The second experiment is a direct comparison of the MCD bottle and World Health Organization (WHO) cone bioassay that tests a subset of the insecticides (a piece of LLIN and a piece of netting coated with B. bassiana spores) and a further reduced exposure time (5 seconds) against both An. stephensi and Anopheles gambiae. Immediate knockdown and mortality after 24 hours were assessed using logistic regression and daily survival was assessed using Cox proportional hazards models. Across both experiments, fungus performed much more consistently than the chemical insecticides but measuring the effect of fungus required monitoring of mosquito mortality over several days to a week. Qualitatively, the MCD bottle and WHO cone performed comparably

Ancient water bottle use and polycyclic aromatic hydrocarbon (PAH) exposure among California Indians: a prehistoric health risk assessment.

PubMed

Sholts, Sabrina B; Smith, Kevin; Wallin, Cecilia; Ahmed, Trifa M; Wärmländer, Sebastian K T S

2017-06-23

Polycyclic aromatic hydrocarbons (PAHs) are the main toxic compounds in natural bitumen, a fossil material used by modern and ancient societies around the world. The adverse health effects of PAHs on modern humans are well established, but their health impacts on past populations are unclear. It has previously been suggested that a prehistoric health decline among the native people living on the California Channel Islands may have been related to PAH exposure. Here, we assess the potential health risks of PAH exposure from the use and manufacture of bitumen-coated water bottles by ancient California Indian societies. We replicated prehistoric bitumen-coated water bottles with traditional materials and techniques of California Indians, based on ethnographic and archaeological evidence. In order to estimate PAH exposure related to water bottle manufacture and use, we conducted controlled experiments to measure PAH contamination 1) in air during the manufacturing process and 2) in water and olive oil stored in a completed bottle for varying periods of time. Samples were analyzed with gas chromatography/mass spectrometry (GC/MS) for concentrations of the 16 PAHs identified by the US Environmental Protection Agency (EPA) as priority pollutants. Eight PAHs were detected in concentrations of 1-10 μg/m 3 in air during bottle production and 50-900 ng/L in water after 2 months of storage, ranging from two-ring (naphthalene and methylnaphthalene) to four-ring (fluoranthene) molecules. All 16 PAHs analyzed were detected in olive oil after 2 days (2 to 35 μg/kg), 2 weeks (3 to 66 μg/kg), and 2 months (5 to 140 μg/kg) of storage. For ancient California Indians, water stored in bitumen-coated water bottles was not a significant source of PAH exposure, but production of such bottles could have resulted in harmful airborne PAH exposure.

A virus of hyperthermophilic archaea with a unique architecture among DNA viruses.

PubMed

Rensen, Elena Ilka; Mochizuki, Tomohiro; Quemin, Emmanuelle; Schouten, Stefan; Krupovic, Mart; Prangishvili, David

2016-03-01

Viruses package their genetic material in diverse ways. Most known strategies include encapsulation of nucleic acids into spherical or filamentous virions with icosahedral or helical symmetry, respectively. Filamentous viruses with dsDNA genomes are currently associated exclusively with Archaea. Here, we describe a filamentous hyperthermophilic archaeal virus, Pyrobaculum filamentous virus 1 (PFV1), with a type of virion organization not previously observed in DNA viruses. The PFV1 virion, 400 ± 20 × 32 ± 3 nm, contains an envelope and an inner core consisting of two structural units: a rod-shaped helical nucleocapsid formed of two 14-kDa major virion proteins and a nucleocapsid-encompassing protein sheath composed of a single major virion protein of 18 kDa. The virion organization of PFV1 is superficially similar to that of negative-sense RNA viruses of the family Filoviridae, including Ebola virus and Marburg virus. The linear dsDNA of PFV1 carries 17,714 bp, including 60-bp-long terminal inverted repeats, and contains 39 predicted ORFs, most of which do not show similarities to sequences in public databases. PFV1 is a lytic virus that completely disrupts the host cell membrane at the end of the infection cycle.

Effects of storage temperature and time of antimony release from PET bottles into drinking water in China.

PubMed

Qiao, Fei; Lei, Kun; Li, Zicheng; Liu, Qing; Wei, Zhanliang; An, Lihui; Qi, Hongli; Cui, Song

2018-01-01

Antimony (Sb) concentrations were measured in 10 brands of PET bottled drinking water available in supermarkets in China. To simulate general storage habits based on market research, these PET bottles with drinking water were stored for 4 weeks in a lab or a car trunk during the summer. Although the PET package material of brand A had the lowest Sb level (142.71 ± 29.81 μg/g), it showed a significant increase in Sb concentrations when stored in both the car trunk and the lab. There was significant release of Sb from the PET bottles into the water following 24 h of incubation at ≥ 40 °C (40, 50, 60, and 70 °C), especially at 70 °C. The potential health risk of Sb release from PET bottles was calculated based on daily intake values and determined to be acceptable for consumers under normal storage conditions.

A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

PubMed Central

Dittmann, Meike; Hoffmann, Hans-Heinrich; Scull, Margaret A.; Gilmore, Rachel H.; Bell, Kierstin L.; Ciancanelli, Michael; Wilson, Sam J.; Crotta, Stefania; Yu, Yingpu; Flatley, Brenna; Xiao, Jing W.; Casanova, Jean-Laurent; Wack, Andreas; Bieniasz, Paul D.; Rice, Charles M.

2015-01-01

Summary Interferon-stimulated genes (ISGs) act in concert to provide a tight barrier against viruses. Recent studies have shed light on the contribution of individual ISG effectors to the antiviral state, but most have examined those acting on early, intracellular stages of the viral life cycle. Here, we applied an image-based screen to identify ISGs inhibiting late stages of influenza A virus (IAV) infection. We unraveled a directly antiviral function for the gene SERPINE1, encoding plasminogen activator inhibitor 1 (PAI-1). By targeting extracellular airway proteases, PAI-1 inhibits IAV glycoprotein cleavage, thereby reducing infectivity of progeny viruses. This was biologically relevant for IAV restriction in vivo. Further, partial PAI-1 deficiency, attributable to a polymorphism in human SERPINE1, conferred increased susceptibility to IAV in vitro. Together, our findings reveal that manipulating the extracellular environment to inhibit the last step in a virus life cycle is an important mechanism of the antiviral response. PMID:25679759

Corning HYPERFlask® for viral amplification and production of diagnostic reagents.

PubMed

Kearney, Brian J; Voorhees, Matthew A; Williams, Priscilla L; Olschner, Scott P; Rossi, Cynthia A; Schoepp, Randal J

2017-04-01

Viral preparations are essential components in diagnostic research and development. The production of large quantities of virus traditionally is done by infecting numerous tissue culture flasks or roller bottles, which require large incubators and/or roller bottle racks. The Corning HYPERFlask ® is a multilayer flask that uses a gas permeable film to provide gas exchange between the cells and culture medium and the atmospheric environment. This study evaluated the suitability of the HYPERFlask for production of Lassa, Ebola, Bundibugyo, Reston, and Marburg viruses and compared it to more traditional methods using tissue culture flasks and roller bottles. The HYPERFlask produced cultures were equivalent in virus titer and indistinguishable in immunodiagnostic assays. The use of the Corning HYPERFlask for viral production is a viable alternative to traditional tissue culture flasks and roller bottles. HYPERFlasks allow for large volumes of virus to be produced in a small space without specialized equipment. Copyright © 2016. Published by Elsevier B.V.

Molecular and macromolecular changes in bottle-aged white wines reflect oxidative evolution – Impact of must clarification and bottle closure

NASA Astrophysics Data System (ADS)

Coelho, Christian; Julien, Perrine; Nikolantonaki, Maria; Noret, Laurence; Magne, Mathilde; Ballester, Jordi; Gougeon, Régis D.

2018-04-01

Chardonnay wines from Burgundy, obtained from musts with three levels of clarification (Low, Medium and High) during two consecutive vintages (2009 and 2010) and for two kinds of closures (screw caps and synthetic coextruded closures) were analyzed chemically and sensorially. Three bottles per turbidity level were opened in 2015 in order to assess the intensity of the reductive and/or oxidative aromas (REDOX sensory scores) by a trained sensory panel. The chemical analyses consisted in polyphenols and colloids quantification, followed by a proteomic characterization. For the two vintages, the REDOX sensory scores appeared to be driven both by the type of closure and to a lesser extent by the level of must clarification. Vintages and must racking prefermentative operations were also distinguished by chemical analyses. All white wines from the lowest must turbidity had the lowest REDOX sensory scores. Such wines exhibited lower concentrations in tyrosol and grape reaction product and higher concentrations in colloids with relatively low molecular weights. Among these macromolecules, grape proteins were also quantified, two of them exhibiting concentrations in bottled wines, which were statistically correlated to oxidative evolution in white wines

Why some women do not breast feed: bottle feeding and fathers' role.

PubMed

Earle, S

2000-12-01

To explore women's experiences and perceptions of baby feeding and to explore the explanations offered by women who choose to either breast or bottle feed. A qualitative study, which was prospective in design. Participants were interviewed three times: the first stage was between six and 14 weeks of pregnancy; the second stage was between 34 and 39 weeks; and the third stage was between six and 14 weeks after childbirth. 19 participants were recruited to the study group via 12 antenatal clinics in Coventry, UK. The data indicate that participants make baby-feeding decisions either prior to conception or early in the pregnancy. Findings also indicate that both breast and bottle feeders possessed knowledge of the benefits of breast feeding, but this did not seem to influence decision making. One of the most significant factors influencing the decision to bottle feed appears to be a desire for paternal involvement. To increase the incidence of breast feeding, health-care professionals should consider the need for preconceptual health promotion. The role of paternal involvement in baby-feeding decisions also needs to be acknowledged and men need to be included in breast-feeding promotion campaigns.

Breast vs. bottle: a new controversy.

PubMed

Caruncho, E S

1979-01-01

The infant feeding controversy had its roots in the early 1960s, when the declining birth rate in industrialized countries led the multinational baby food manufacturers to look to the fast growing populations of the 3rd World to bolster their sales. The connection between infant formula, malnutrition, and infant mortality has been increasingly recognized by the World Health Organization and other groups and individuals. The expense of infant formula, overdilution by impoverished parents attempting to stretch the food budget, and poor sanitary conditions made millions of 3rd World babies victims of malnutrition, infectious diseases, and premature death. In 1974, the British public interest group called War on Want launched an international campaign against the aggressive promotional practices of the infant formula manufacturers. A nonbinding agreement between the International Council of Infant Food Industries and their critics in Geneva in 1979 was regarded as a truce rather than a solution to the controversy, but worldwide attention was attracted to the infant feeding issue. Scientific research has confirmed the advantages of breast feeding in providing immunity as well as optimal nutrition and contraceptive protection. Although greater convenience, necessity of working outside the home, or insufficient milk lead some mothers to bottle feed, misleading and aggressive promotional campaigns of the infant feeding companies have been very effective in persuading mothers of all income levels to choose bottle feeding. With increasing realization of the benefits of breast feeding, efforts are now underway to reverse the trends.

Electrochemical Characterisation of Bio-Bottle-Voltaic (BBV) Systems Operated with Algae and Built with Recycled Materials.

PubMed

Bateson, Peter; Fleet, Jack E H; Riseley, Anthony S; Janeva, Elena; Marcella, Anastasia S; Farinea, Chiara; Kuptsova, Maria; Conde Pueyo, Núria; Howe, Christopher J; Bombelli, Paolo; Parker, Brenda M

2018-04-17

Photobioelectrochemical systems are an emerging possibility for renewable energy. By exploiting photosynthesis, they transform the energy of light into electricity. This study evaluates a simple, scalable bioelectrochemical system built from recycled plastic bottles, equipped with an anode made from recycled aluminum, and operated with the green alga Chlorella sorokiniana . We tested whether such a system, referred to as a bio-bottle-voltaic (BBV) device, could operate outdoors for a prolonged time period of 35 days. Electrochemical characterisation was conducted by measuring the drop in potential between the anode and the cathode, and this value was used to calculate the rate of charge accumulation. The BBV systems were initially able to deliver ~500 mC·bottle −1 ·day −1 , which increased throughout the experimental run to a maximum of ~2000 mC·bottle −1 ·day −1 . The electrical output was consistently and significantly higher than that of the abiotic BBV system operated without algal cells (~100 mC·bottle −1 ·day −1 ). The analysis of the rate of algal biomass accumulation supported the hypothesis that harvesting a proportion of electrons from the algal cells does not significantly perturb the rate of algal growth. Our finding demonstrates that bioelectrochemical systems can be built using recycled components. Prototypes of these systems have been displayed in public events; they could serve as educational toolkits in schools and could also offer a solution for powering low-energy devices off-grid.

21 CFR 1250.42 - Water systems; constant temperature bottles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Water systems; constant temperature bottles. 1250.42 Section 1250.42 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION...

NASA-Enhanced Water Bottles Filter Water on the Go

NASA Technical Reports Server (NTRS)

2014-01-01

Complex systems on the ISS collect and recycle moisture from every possible source-including sweat and urine-to be filtered for recycled use. Greenbrae, California-based ÖKO now sells a water bottle that employs NASA filtration media to purify water as the user squeezes it through the device.

A Computer Model for Soda Bottle Oscillations: "The Bottelator".

ERIC Educational Resources Information Center

Soltzberg, Leonard J.; And Others

1997-01-01

Presents a model to explain the behavior of oscillatory phenomena found in the soda bottle oscillator. Describes recording the oscillations, and the design of the model based on the qualitative explanation of the oscillations. Illustrates a variety of physiochemical concepts including far-from-equilibrium oscillations, feedback, solubility and…

Brettanomyces bruxellensis evolution and volatile phenols production in red wines during storage in bottles.

PubMed

Coulon, J; Perello, M C; Lonvaud-Funel, A; de Revel, G; Renouf, V

2010-04-01

The presence of Brettanomyces bruxellensis is an important issue during winemaking because of its volatile phenols production capacities. The aim of this study is to provide information on the ability of residual B. bruxellensis populations to multiply and spoil finished wines during storage in bottles. Several finished wines were studied. Brettanomyces bruxellensis populations were monitored during two and a half months, and volatile phenols as well as chemical parameters regularly determined. Variable growth and volatile phenols synthesis capacities were evidenced, in particularly when cells are in a noncultivable state. In addition, the volatile phenol production was clearly shown to be a two-step procedure that could strongly be correlated to the physiological state of the yeast population. This study underlines the importance of minimizing B. bruxellensis populations at the end of wine ageing to reduce volatile phenols production risk once the wine in bottle. Moreover, the physiological state of the yeast seems to have an important impact on ethyl-phenols production, hence demonstrating the importance of taking into account this parameter when analysing wine spoilage risks. Little data exist about the survival of B. bruxellensis once the wine in bottle. This study provides information on the alteration risks encountered during wine storage in bottle and reveals the importance of carrying on further studies to increase the knowledge on B. bruxellensis physiology.

Morphology of certain viruses of Salmonid fishes. II. In vivo studies of infectious Hematopoietic Necrosis Virus

USGS Publications Warehouse

Amend, Donald F.; Chambers, Velma C.

1970-01-01

Juvenile sockeye salmon (Oncorhynchus nerka) were injected with the infectious hematopoietic necrosis (IHN) virus, and tissue samples from the anterior kidney, spleen, liver, intestine, and pyloric caeca of moribund fish were prepared for electron microscopy. Bullet-shaped virus particles measuring 158 × 90 mμ were observed in the hematopoietic tissues of the anterior kidney and spleen. Virus particles were also observed in the outer connective tissues of the pancreas or pyloric caeca, or both. No virus was found in the intestine or liver. The healthy appearance of erythrocytes, reticular cells, and endothelial cells in necrotic areas of the spleen and anterior kidney, and the absence of lymphocytes in these areas, suggested that lymphocytes might be one source of the virus.

Evaluation of a new generation of plastic culture bottles with an automated microbial detection system for nine common contaminating organisms found in PLT components.

PubMed

Brecher, M E; Hay, S N; Rothenberg, S J

2004-03-01

A microbial detection system (BacT/ALERT 3D, bioMérieux [formerly Organon Teknika]) has previously been validated with a variety of bacterial contaminants in PLTs. The recovery of nine organisms seeded into PLTs with new plastic culture bottles was studied in comparison to the current glass bottles. The use of plastic instead of glass would be expected to reduce the risk of injury. Isolates of Bacillus cereus, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis, Serratia marcescens, Streptococcus viridans, and Propionibacterium acnes were inoculated into Day 2 (>24 hr <48 hr) apheresis PLT units to 10 and 100 CFUs per mL. Replicate samples (4 mL) were inoculated into both current- and new-generation standard aerobic and anaerobic bottles. All organisms (with the exception of P. acnes) were detected in a mean time of 9.3 to 18.9 hours (10 CFUs/mL) or 8.7 to 18.2 hours (100 CFUs/mL). In aggregate (with the exception of P. acnes), the plastic and glass aerobic bottles had a mean difference in detection of 1.2 hours (p < 0.0001), and the plastic and glass anaerobic bottles had a mean difference of 3.3 hours (p < 0.0001). In all cases, the mean detection time was superior or clinically comparable (within 0.1 hr) with the new plastic bottles. P. acnes (an anaerobic organism) was detected with the new and current anaerobic bottles in a mean of 72.8 and 90.4 hours (10 CFUs/mL) or 64.0 and 80.8 hours (100 CFUs/mL), respectively. The narrower bottle neck and smaller inoculation septum present with the new-generation plastic bottles were inoculated with comparable ease to that of the glass bottles. These data demonstrate that the new plastic bottles are clinically comparable or superior to the current glass standard aerobic and anaerobic culture bottles.

Exploring Klein Bottles through Pottery: A STEAM Investigation

ERIC Educational Resources Information Center

Smith, Christopher E.; Paré, Jana N.

2016-01-01

While one author was reading "The Simpsons and Their Mathematical Secrets by Simon Singh" (2013) in preparation for a presentation, the second author asked what in the book would be interesting to discuss. The topic of Klein bottles was on the first author's mind at that moment, so he tried to describe and explain the form to her--a real…

Leaching of styrene and other aromatic compounds in drinking water from PS bottles.

PubMed

Ahmad, Maqbool; Bajahlan, Ahmad S

2007-01-01

Bottled water may not be safer, or healthier, than tap water. The present studies have proved that styrene and some other aromatic compounds leach continuously from polystyrene (PS) bottles used locally for packaging. Water sapmles in contact with PS were extracted by a preconcentration technique called as "purge and trap" and analysed by gas chromatograph-mass spectrometer (GC/MS). Eleven aromatic compounds were identified in these studies. Maximum concentration of styrene in PS bottles was 29.5 microg/L. Apart from styrene, ethyl benzene, toluene and benzene were also quantified but their concentrations were much less than WHO guide line values. All other compounds were in traces. Quality of plastic and storage time were the major factor in leaching of styrene. Concentration of styrene was increased to 69.53 microg/L after one-year storage. In Styrofoam and PS cups studies, hot water was found to be contaminated with styrene and other aromatic compounds. It was observed that temperature played a major role in the leaching of styrene monomer from Styrofoam cups. Paper cups were found to be safe for hot drinks.

21 CFR 1250.42 - Water systems; constant temperature bottles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... reconstructed conveyances, water coolers shall be an integral part of the closed system. (d) Water filters if... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Water systems; constant temperature bottles. 1250... INTERSTATE CONVEYANCE SANITATION Equipment and Operation of Land and Air Conveyances § 1250.42 Water systems...

21 CFR 1250.42 - Water systems; constant temperature bottles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... reconstructed conveyances, water coolers shall be an integral part of the closed system. (d) Water filters if... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Water systems; constant temperature bottles. 1250... INTERSTATE CONVEYANCE SANITATION Equipment and Operation of Land and Air Conveyances § 1250.42 Water systems...

Development and application of a non-targeted extraction method for the analysis of migrating compounds from plastic baby bottles by GC-MS.

PubMed

Onghena, Matthias; van Hoeck, Els; Vervliet, Philippe; Scippo, Marie Louise; Simon, Coraline; van Loco, Joris; Covaci, Adrian

2014-01-01

In 2011, the European Union prohibited the production of polycarbonate (PC) baby bottles due to the toxic effects of the PC monomer bisphenol-A. Therefore, baby bottles made of alternative materials, e.g. polypropylene (PP) or polyethersulphone (PES), are currently marketed. The principal aim of the study was the identification of major compounds migrating from baby bottles using a liquid-liquid extraction followed by GC/MS analysis. A 50% EtOH in water solution was selected as a simulant for milk. After sterilisation of the bottle, three migration experiments were performed during 2 h at 70°C. A non-targeted liquid-liquid extraction with ethyl acetate-n-hexane (1:1) was performed on the simulant samples. Identification of migrants from 24 baby bottles was done using commercially available WILEY and NIST mass spectra libraries. Differences in the migrating compounds and their intensities were observed between the different types of plastics, but also between the same polymer from a different producer. Differences in the migration patterns were perceived as well between the sterilisation and the migrations and within the different migrations. Silicone, Tritan™ and PP exhibited a wide variety of migrating compounds, whereas PES and polyamide (PA) showed a lower amount of migrants, though sometimes in relatively large concentrations (azacyclotridecan-2-one up to 250 µg kg⁻¹). Alkanes (especially in PP bottles), phthalates (dibutylphthalate in one PP bottle (±40 µg kg⁻¹) and one silicone bottle (±25 µg kg⁻¹); diisobutylphthalate in one PP (±10 µg kg⁻¹), silicone (up to ±80 µg kg⁻¹); and Tritan™ bottle (±30 µg kg⁻¹)), antioxidants (Irgafos 168, degradation products of Irganox 1010 and Irganox 1076), etc. were detected for PP, silicone and Tritan™ bottles. Although the concentrations were relatively low, some compounds not authorised by European Union Regulation No. 10/2011, such as 2,4-di-tert-butylphenol (10-100 µg kg⁻¹) or 2

Automatic external filling for the ion source gas bottle of a Van de Graaff accelerator

NASA Astrophysics Data System (ADS)

Strivay, D.; Bastin, T.; Dehove, C.; Dumont, P. D.; Marchal, A.; Garnir, H.; Weber, G.

1997-09-01

We describe a fully automatic system we developed to fill, from an external gas bottle, the ion source terminal gas storage bottle of a 2 MV Van de Graaff accelerator without depressing the 25 bar insulating gas. The system is based on a programmable automate ordering electropneumatical valves. The only manual operation is the connection of the external gas cylinder. The time needed for a gas change is reduced to typically 15 min (depending on the residual pressure wished for the gas removed from the terminal bottle). To check this system we study the ionic composition of the ion beam delivered by our accelerator after different gas changes. The switching magnet of our accelerator was used to analyse the ionic composition of the accelerated beams in order to verify the degree of elimination of the previous gases in the system.

Age determination of bottled Chinese rice wine by VIS-NIR spectroscopy

NASA Astrophysics Data System (ADS)

Yu, Haiyan; Lin, Tao; Ying, Yibin; Pan, Xingxiang

2006-10-01

The feasibility of non-invasive visible and near infrared (VIS-NIR) spectroscopy for determining wine age (1, 2, 3, 4, and 5 years) of Chinese rice wine was investigated. Samples of Chinese rice wine were analyzed in 600 mL square brown glass bottles with side length of approximately 64 mm at room temperature. VIS-NIR spectra of 100 bottled Chinese rice wine samples were collected in transmission mode in the wavelength range of 350-1200 nm by a fiber spectrometer system. Discriminant models were developed based on discriminant analysis (DA) together with raw, first and second derivative spectra. The concentration of alcoholic degree, total acid, and °Brix was determined to validate the NIR results. The calibration result for raw spectra was better than that for first and second derivative spectra. The percentage of samples correctly classified for raw spectra was 98%. For 1-, 2-, and 3-year-old sample groups, the sample were all correctly classified, and for 4- and 5-year-old sample groups, the percentage of samples correctly classified was 92.9%, respectively. In validation analysis, the percentage of samples correctly classified was 100%. The results demonstrated that VIS-NIR spectroscopic technique could be used as a non-invasive, rapid and reliable method for predicting wine age of bottled Chinese rice wine.

10 CFR 431.294 - Uniform test method for the measurement of energy consumption of refrigerated bottled or canned...

Code of Federal Regulations, 2011 CFR

2011-01-01

... consumption of refrigerated bottled or canned beverage vending machines. 431.294 Section 431.294 Energy... EQUIPMENT Refrigerated Bottled or Canned Beverage Vending Machines Test Procedures § 431.294 Uniform test... machines. (a) Scope. This section provides test procedures for measuring, pursuant to EPCA, the energy...

Soil-borne wheat mosaic virus infectious clone and manipulation for gene-carrying capacity

USDA-ARS?s Scientific Manuscript database

Soilborne wheat mosaic virus (SBWMV) is a bipartite single stranded positive sense RNA virus with rigid-rod shaped virions. Taxonomically the virus is in the family Viragviridae, as are commonly used gene silencing or expression viral vectors, Tobacco rattle virus (TRV) and Barley stripe mosaic viru...

Bottled, filtered, and tap water use in Latino and non-Latino children.

PubMed

Hobson, Wendy L; Knochel, Miguel L; Byington, Carrie L; Young, Paul C; Hoff, Charles J; Buchi, Karen F

2007-05-01

To describe bottled, filtered, and tap water consumption and fluoride use among pediatric patients; to analyze differences between ethnic and socioeconomic groups; and to describe the frequency of physician-parent discussions regarding water consumption. Convenience sample survey. An urban public health clinic. Parents attending a public health clinic. The primary outcome measure was the prevalence of tap, filtered, and bottled water use. The secondary outcome measures were supplemental fluoride use and the percentage of patients reporting discussions of water consumption with their physician. A total of 216 parents (80.5% Latino and 19.5% non-Latino) completed the survey. Of the parents, 30.1% never drank tap water and 41.2% never gave it to their children. Latino parents were less likely than non-Latino parents to drink tap water (odds ratio, 0.26; 95% confidence interval, 0.10-0.67) and less likely to give tap water to their children (odds ratio, 0.32; 95% confidence interval, 0.15-0.70). More Latinos believed that tap water would make them sick (odds ratio, 5.63; 95% confidence interval, 2.17-14.54). Approximately 40% of children who never drank tap water were not receiving fluoride supplements. Of the lowest-income families (bottled (32.9%) or filtered (32.0%) water to their children. Of the parents surveyed, 82.5% reported that their child's physician had never discussed the type of water they should use. Many Latino families avoid drinking tap water because they fear it causes illness. Unnecessary use of bottled and filtered water is costly and may result in adverse dental health outcomes. Physicians should provide guidance to families regarding the safety, low cost, and dental health benefits of drinking tap water.

Whoosh Bottle Safety, Again: What about What Is inside?

ERIC Educational Resources Information Center

Gregory, Robert B.; Lauber, Matthew

2012-01-01

Studies regarding the whoosh bottle combustion experiment have largely focused on the detonation hazard of the demonstration, particularly with regards to fuel and container choice. Previous work has suggested that the fuel should be 2-propanol owing to its relatively cool flame characteristics. The current study has found that the combustion of…

21 CFR 1250.42 - Water systems; constant temperature bottles.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Water systems; constant temperature bottles. 1250.42 Section 1250.42 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION INTERSTATE CONVEYANCE SANITATION Equipment and...

Soda bottle water rockets - a project students (seem to) like

NASA Astrophysics Data System (ADS)

Eliasson, Veronica

2017-11-01

In this talk I will present my experience of developing and leading an undergraduate student project for a junior level Fluid Mechanics course. My goal was to let students participate in a project that would help them to develop and retain a better understanding for several fluid mechanics concepts, while simultaneously being challenged in an interesting and fun way. Thus, students were divided into teams and asked to complete two things: 1) determine using theory mixed with numerical estimates how much water to add to the soda bottle given a maximum amount of allowable pressure for their bottle rocket; and 2) design, build and fly a rocket with the goal of reaching as high of an altitude as possible. I'll also talk about the weekly tasks given to students, the results, and finally share some of the comments and perspectives from the participating students.

Viruses: agents of coral disease?

PubMed

Davy, S K; Burchett, S G; Dale, A L; Davies, P; Davy, J E; Muncke, C; Hoegh-Guldberg, O; Wilson, W H

2006-03-23

The potential role of viruses in coral disease has only recently begun to receive attention. Here we describe our attempts to determine whether viruses are present in thermally stressed corals Pavona danai, Acropora formosa and Stylophora pistillata and zoanthids Zoanthus sp., and their zooxanthellae. Heat-shocked P. danai, A. formosa and Zoanthus sp. all produced numerous virus-like particles (VLPs) that were evident in the animal tissue, zooxanthellae and the surrounding seawater; VLPs were also seen around heat-shocked freshly isolated zooxanthellae (FIZ) from P. danai and S. pistillata. The most commonly seen VLPs were tail-less, hexagonal and about 40 to 50 nm in diameter, though a diverse range of other VLP morphotypes (e.g. rounded, rod-shaped, droplet-shaped, filamentous) were also present around corals. When VLPs around heat-shocked FIZ from S. pistillata were added to non-stressed FIZ from this coral, they resulted in cell lysis, suggesting that an infectious agent was present; however, analysis with transmission electron microscopy provided no clear evidence of viral infection. The release of diverse VLPs was again apparent when flow cytometry was used to enumerate release by heat-stressed A. formosa nubbins. Our data support the infection of reef corals by viruses, though we cannot yet determine the precise origin (i.e. coral, zooxanthellae and/or surface microbes) of the VLPs seen. Furthermore, genome sequence data are required to establish the presence of viruses unequivocally.

Identification of Putative Steroid Receptor Antagonists in Bottled Water: Combining Bioassays and High-Resolution Mass Spectrometry

PubMed Central

Wagner, Martin; Schlüsener, Michael P.; Ternes, Thomas A.; Oehlmann, Jörg

2013-01-01

Endocrine disrupting chemicals (EDCs) are man-made compounds interfering with hormone signaling and thereby adversely affecting human health. Recent reports provide evidence for the presence of EDCs in commercially available bottled water, including steroid receptor agonists and antagonists. However, since these findings are based on biological data the causative chemicals remain unidentified and, therefore, inaccessible for toxicological evaluation. Thus, the aim of this study is to assess the antiestrogenic and antiandrogenic activity of bottled water and to identify the causative steroid receptor antagonists. We evaluated the antiestrogenic and antiandrogenic activity of 18 bottled water products in reporter gene assays for human estrogen receptor alpha and androgen receptor. Using nontarget high-resolution mass spectrometry (LTQ-Orbitrap Velos), we acquired corresponding analytical data. We combined the biological and chemical information to determine the exact mass of the tentative steroid receptor antagonist. Further MSn experiments elucidated the molecule’s structure and enabled its identification. We detected significant antiestrogenicity in 13 of 18 products. 16 samples were antiandrogenic inhibiting the androgen receptor by up to 90%. Nontarget chemical analysis revealed that out of 24520 candidates present in bottled water one was consistently correlated with the antagonistic activity. By combining experimental and in silico MSn data we identified this compound as di(2-ethylhexyl) fumarate (DEHF). We confirmed the identity and biological activity of DEHF and additional isomers of dioctyl fumarate and maleate using authentic standards. Since DEHF is antiestrogenic but not antiandrogenic we conclude that additional, yet unidentified EDCs must contribute to the antagonistic effect of bottled water. Applying a novel approach to combine biological and chemical analysis this is the first study to identify so far unknown EDCs in bottled water. Notably

Sample preparation method influences direct identification of anaerobic bacteria from positive blood culture bottles using MALDI-TOF MS.

PubMed

Jeverica, Samo; Nagy, Elisabeth; Mueller-Premru, Manica; Papst, Lea

2018-05-15

Rapid detection and identification of anaerobic bacteria from blood is important to adjust antimicrobial therapy by including antibiotics with activity against anaerobic bacteria. Limited data is available about direct identification of anaerobes from positive blood culture bottles using MALDI-TOF mass spectrometry (MS). In this study, we evaluated the performance of two sample preparation protocols for direct identification of anaerobes from positive blood culture bottles, the MALDI Sepsityper kit (Sepsityper) and the in-house saponin (saponin) method. Additionally, we compared two blood culture bottle types designed to support the growth of anaerobic bacteria, the BacT/ALERT-FN Plus (FN Plus) and the BACTEC-Lytic (Lytic), and their influence on direct identification. A selection of 30 anaerobe strains belonging to 22 different anaerobic species (11 reference strains and 19 clinical isolates) were inoculated to 2 blood culture bottle types in duplicate. In total, 120 bottles were inoculated and 99.2% (n = 119) signalled growth within 5 days of incubation. The Sepsityper method correctly identified 56.3% (n = 67) of anaerobes, while the saponin method correctly identified 84.9% (n = 101) of anaerobes with at least log(score) ≥1.6 (low confidence correct identification), (p < 0.001). Gram negative anaerobes were better identified with the saponin method (100% vs. 46.5%; p < 0.001), while Gram positive anaerobes were better identified with the Sepsityper method (70.8% vs. 62.5%; p = 0.454). Average log(score) values among only those isolates that were correctly identified simultaneously by both sample preparation methods were 2.119 and 2.029 in favour of the Sepsityper method, (p = 0.019). The inoculated bottle type didn't influence the performance of the two sample preparation methods. We confirmed that direct identification from positive blood culture bottles with MALDI-TOF MS is reliable for anaerobic bacteria. However, the results

Ship-in-a-bottle catalysts

DOEpatents

Haw, James F.; Song, Weiguo

2006-07-18

In accordance with the present invention there is provided a novel catalyst system in which the catalytic structure is tailormade at the nanometer scale using the invention's novel ship-in-a-bottle synthesis techniques. The invention describes modified forms of solid catalysts for use in heterogeneous catalysis that have a microporous structure defined by nanocages. Examples include zeolites, SAPOs, and analogous materials that have the controlled pore dimensions and hydrothermal stability required for many industrial processes. The invention provides for modification of these catalysts using reagents that are small enough to pass through the windows used to access the cages. The small reagents are then reacted to form larger molecules in the cages.

Psychological factors in breast feeding versus bottle feeding in the Third World.

PubMed

Meldrum, B

1982-06-01

The increasing use of bottle feeding rather than traditional breastfeeding among mothers in developing countries is causing great concern. The feeding bottle is a powerful symbol of westernization, and it can be very difficult for mothers caught in the transitional period between traditional culture and western culture to understand that the feeding bottle can be, under improper hygienic conditions, dangerous to the health of the baby. The importance of breastfeeding in developing countries lies not only in its nutritional value, but in its effect on fertility, since, in many societies, among them the Yoruba of Nigeria, women used to avoid intercourse during breastfeeding. These traditional customs are breaking down, especially among urban and more educated women, or among those holding jobs; a study conducted in Nigeria reports that more education and modern occupations are dramatically changing feeding patterns; in 1976 80% of moderately educated women, i.e. above primary school level, had stopped breastfeeding by the time their children were 1 year old, compared to only 18% of uneducated women. Moreover, many mothers believe that artificial formula is better than breast milk for babies, and view it as medicine, or as being good for children's health. It seems that a reversal to the practice of exclusive breastfeeding will be impossible in most developing countries.

Reducing Baby Bottle Tooth Decay. A SERVE Research Brief.

ERIC Educational Resources Information Center

Southeastern Regional Vision for Education (SERVE), Tallahassee, FL.

This pamphlet discusses strategies for reducing baby bottle tooth decay (BBTD) among Native American children. BBTD in infants and toddlers is a painful disease characterized by extensive decay of the upper front and side teeth. It is caused by prolonged exposure of teeth to carbohydrates, such as those contained in infant formula, milk, and fruit…

Community challenges when using large plastic bottles for Solar Energy Disinfection of Water (SODIS).

PubMed

Borde, Preeti; Elmusharaf, Khalifa; McGuigan, Kevin G; Keogh, Michael B

2016-09-05

Communities living in developing countries as well as populations affected by natural or man-made disasters can be left at great risk from water related diseases, especially those spread through the faecal-oral route. Conventional water treatments such as boiling and chlorination can be effective but may prove costly for impoverished communities. Solar water disinfection (SODIS) has been shown to be a cheap and effective way for communities to treat their water. The exposure to sunlight is typically carried out in small volume plastic beverage bottles (up to 2 l). Given the water requirements of consumption and basic personal hygiene, this may not always meet the needs of communities. Recent work has shown 19-L plastic water dispenser containers to be effective SODIS reactors, comparable in efficacy to PET bottles. In this paper we outline the need for studying SODIS in large volumes and discuss 4 main associated challenges. Apart from clean water needed for consumption, access to adequate water is essential for sanitation and hygiene. Contamination of treated water through unwashed hands or vessels contributes heavily to the spread of water borne pathogens in communities. Traditional water treatments such as boiling and chlorination can be effective but may prove financially burdensome for low income communities. SODIS in large vessels could be used as a simple method to meet water requirements in low income and disaster affected populations. However, there have been some concerns associated with the conventional SODIS method; we identify the main ones to be: (1) cold or cloudy weather; (2) the fear of leaching in plastic bottles; (3) water turbidity, and; (4) community acceptance. The application of SODIS in large bottles like WDCs has the potential to be an efficient and cost effective method of disinfecting water, either for consumption until more rigorous water treatments can be put in place, or for sanitation and hygiene to curb the spread of fecal

Bacterial contamination of the lacteal contents of feeding bottles in metropolitan São Paulo, Brazil.

PubMed Central

Morais, T. B.; Morais, M. B.; Sigulem, D. M.

1998-01-01

Reported are the results of a study in São Paulo, Brazil, to evaluate the bacterial contamination of the lacteal contents of feeding bottles prepared in urban households of low (LSE) and high (HSE) socioeconomic groups, involving 100 and 32 mothers of infants, respectively. Samples of the lacteal contents of the feeding bottles were cultured and the medians (25th and 75th percentiles) of the counts (bacteria per ml) were significantly higher in the LSE group: mesophilic bacteria, 555,000 (17,250-4,350,000) in the LSE group and 1615 (20-500,000) in the HSE group; coliforms, 2400 (19-150,000) in the LSE group and 7 (0-7800) in the HSE group. Escherichia coli was isolated from 26% (26/100) of the samples from the LSE group and from 6% (2/32) of those from the HSE group (P = 0.03). In the HSE group, higher coliform counts were associated with foodhandlers other than the mother, lower levels of maternal education, the use of pasteurized milk, and the addition of ingredients other than milk. In the LSE group, feeding bottles prepared using tap water and those prepared for infants aged over 6 months had higher coliform counts. In general, the feeding bottles prepared in the households studied were heavily contaminated, especially in the LSE group. PMID:9648358

Blue Bottle Experiment: Learning Chemistry without Knowing the Chemicals

ERIC Educational Resources Information Center

Limpanuparb, Taweetham; Areekul, Cherprang; Montriwat, Punchalee; Rajchakit, Urawadee

2017-01-01

The blue bottle experiment is a popular chemical demonstration because of its simplicity and visual appeal. Most papers on the topic focus on a new formulation or a new presentation, but only a few discuss pedagogical application for a full lab session. This article describes the use of this experiment in the first session of undergraduate…

Characterization of Sulfolobus islandicus rod-shaped virus 2 gp19, a single-strand specific endonuclease.

PubMed

Gardner, Andrew F; Prangishvili, David; Jack, William E

2011-09-01

The hyperthermophilic Sulfolobus islandicus rod-shaped virus 2 (SIRV2) encodes a 25-kDa protein (SIRV2gp19) annotated as a hypothetical protein with sequence homology to the RecB nuclease superfamily. Even though SIRV2gp19 homologs are conserved throughout the rudivirus family and presumably play a role in the viral life cycle, SIRV2gp19 has not been functionally characterized. To define the minimal requirements for activity, SIRV2gp19 was purified and tested under varying conditions. SIRV2gp19 is a single-strand specific endonuclease that requires Mg(2+) for activity and is inactive on double-stranded DNA. A conserved aspartic acid in RecB nuclease superfamily Motif II (D89) is also essential for SIRV2gp19 activity and mutation to alanine (D89A) abolishes activity. Therefore, the SIRV2gp19 cleavage mechanism is similar to previously described RecB nucleases. Finally, SIRV2gp19 single-stranded DNA endonuclease activity could play a role in host chromosome degradation during SIRV2 lytic infection.

Maturational changes in the feeding behaviour of infants - a comparison between breast-feeding and bottle-feeding.

PubMed

Taki, M; Mizuno, K; Murase, M; Nishida, Y; Itabashi, K; Mukai, Y

2010-01-01

To obtain a better understanding of the changes in feeding behaviour from 1 to 6 months of age. By comparing breast- and bottle-feeding, we intended to clarify the difference in longitudinal sucking performance. Sucking variables were consecutively measured for 16 breast-fed and eight bottle-fed infants at 1, 3 and 6 months of age. For breast-feeding, number of sucks per burst (17.8 +/- 8.8, 23.8 +/- 8.3 and 32.4 +/- 15.3 times), sucking burst duration (11.2 +/- 6.1, 14.7 +/- 8.0 and 17.9 +/- 8.8 sec) and number of sucking bursts per feed (33.9 +/- 13.9, 28.0 +/- 18.2 and 18.6 +/- 12.8 times) at 1, 3 and 6 months of age respectively showed significant differences between 1 and 6 months of age (p < 0.05). The sucking pressure and total number of sucks per feed did not differ among different ages. Bottle-feeding resulted in longer sucking bursts and more sucks per burst compared with breast-feeding in each month (p < 0.05). The increase in the amount of ingested milk with maturation resulted from an increase in bolus volume per minute as well as the higher number of sucks continuously for both breast- and bottle-fed infants.

Predictors of Drinking Water Boiling and Bottled Water Consumption in Rural China: A Hierarchical Modeling Approach.

PubMed

Cohen, Alasdair; Zhang, Qi; Luo, Qing; Tao, Yong; Colford, John M; Ray, Isha

2017-06-20

Approximately two billion people drink unsafe water. Boiling is the most commonly used household water treatment (HWT) method globally and in China. HWT can make water safer, but sustained adoption is rare and bottled water consumption is growing. To successfully promote HWT, an understanding of associated socioeconomic factors is critical. We collected survey data and water samples from 450 rural households in Guangxi Province, China. Covariates were grouped into blocks to hierarchically construct modified Poisson models and estimate risk ratios (RR) associated with boiling methods, bottled water, and untreated water. Female-headed households were most likely to boil (RR = 1.36, p < 0.01), and among boilers those using electric kettles rather than pots had higher income proxies (e.g., per capita TV ownership RR = 1.42, p < 0.01). Higher-income households with younger, literate, and male heads were more likely to purchase (frequently contaminated) bottled water, or use electric kettles if they boiled. Our findings show that boiling is not an undifferentiated practice, but one with different methods of varying effectiveness, environmental impact, and adoption across socioeconomic strata. Our results can inform programs to promote safer and more efficient boiling using electric kettles, and suggest that if rural China's economy continues to grow then bottled water use will increase.

Assessing human exposure to phthalic acid and phthalate esters from mineral water stored in polyethylene terephthalate and glass bottles.

PubMed

Montuori, P; Jover, E; Morgantini, M; Bayona, J M; Triassi, M

2008-04-01

Phthalic acid and phthalate esters are of growing interest due to their significant usage and potential toxicity. Polyethylene terephthalate (PET) and glass are both widely used materials for bottled drinking water. In this study, phthalic acid (PhA), bis(2-ethylhexyl) phthalate (DEHP), dimethyl phthalate (DMP), diethyl phthalate (DEP), diisobutyl phthalate (DiisoBP) and dibutyl phthalate (DBP) were analysed in a large number of Italian bottled water samples. These samples showed different concentrations of phthalates are nearly 20 times higher in samples bottled in PET than those from glass bottles with total levels of phthalates of 3.52 and 0.19 microg l(-1), respectively. However, the observed levels do not represent a significant exposure pathway when considering the US Environmental Protection Agency (USEPA) reference dose (an estimate of a daily oral exposure to the human population, including sensitive subgroups, that is likely to be without an appreciable risk of deleterious effects during a lifetime). In addition, no significant correlation was found between the phthalate concentrations and the physicochemical properties of the different water samples, apart from the still/sparkling water parameter for the PET samples. In this instance, slightly higher concentrations were observed for the PET bottled still water samples than for the sparkling water samples, although no explanation has been found yet.

A complete life cycle assessment of high density polyethylene plastic bottle

NASA Astrophysics Data System (ADS)

Treenate, P.; Limphitakphong, N.; Chavalparit, O.

2017-07-01

This study was aimed to determine environmental performances of a lubricant oil bottle made from high density polyethylene and to develop potential measures for reducing its impacts. A complete life cycle assessment was carried out to understand a whole effect on the environment from acquiring, processing, using, and disposing the product. Two scenarios of disposal phase; recycle and incineration: were examined to quantify a lesser degree on environmental impact. The results illustrated that major impacts of the two scenarios were at the same categories with the highest contributor of raw material acquisition and pre-processing. However, all impacts in case of recycling provided a lower point than that in case of incineration, except mineral extraction. Finally, feasible measures for reducing the environmental impact of high density polyethylene plastic bottle were proposed in accordance with 3Rs concept.

Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bukreyev, Alexander; Marzi, Andrea; Feldmann, Friederike

2009-01-20

We generated a new live-attenuated vaccine against Ebola virus (EBOV) based on a chimeric virus HPIV3/{delta}F-HN/EboGP that contains the EBOV glycoprotein (GP) as the sole transmembrane envelope protein combined with the internal proteins of human parainfluenza virus type 3 (HPIV3). Electron microscopy analysis of the virus particles showed that they have an envelope and surface spikes resembling those of EBOV and a particle size and shape resembling those of HPIV3. When HPIV3/{delta}F-HN/EboGP was inoculated via apical surface of an in vitro model of human ciliated airway epithelium, the virus was released from the apical surface; when applied to basolateral surface,more » the virus infected basolateral cells but did not spread through the tissue. Following intranasal (IN) inoculation of guinea pigs, scattered infected cells were detected in the lungs by immunohistochemistry, but infectious HPIV3/{delta}F-HN/EboGP could not be recovered from the lungs, blood, or other tissues. Despite the attenuation, the virus was highly immunogenic, and a single IN dose completely protected the animals against a highly lethal intraperitoneal challenge of guinea pig-adapted EBOV.« less

Substitution of water or fresh juice for bottled juice and type 2 diabetes incidence: The SUN cohort study.

PubMed

Fresan, U; Gea, A; Bes-Rastrollo, M; Basterra-Gortari, F J; Carlos, S; Martinez-Gonzalez, M A

2017-10-01

The relationship between juice consumption and type 2 diabetes (T2D) has not been widely evidenced. Our aims were to prospectively evaluate the associations with T2D incidence of: 1) isovolumetric substitution of a water serving/day for one of fruit juice (different types), and of fresh fruit juice for its bottled version; 2) consumption of total, fresh or bottled juice; 3) energy intake from juices. We followed 17,518 adults without T2D at baseline. Beverage consumption was assessed at baseline through a validated food-frequency questionnaire. The outcome was T2D incidence, according to American Diabetes Association's criteria. During a median follow-up of 10.2 years, 142 incident cases of T2D were identified. In substitution models, the substitution of water for bottled juice was associated with a lower T2D incidence, and also if the replacement was done by fresh juice, or especially fresh orange juice [HR 0.75 (95% CI 0.57-0.99), 0.65 (95% CI 0.43-0.98) and 0.56 (95% CI 0.34-0.92); respectively]. Each additional serving/day of bottled juice was directly associated with T2D incidence [HR 1.33 (95% CI 1.01-1.75)]. No significant association was observed for energy coming for bottled juice [HR 1.74 (95% CI 0.94-3.20)]. Our results suggest that isovolumetric substitution of water or fresh juice for bottled juice was inversely associated with T2D incidence in a long-term prospective study. Thus, these substitutions could be useful to tackle the diabetes epidemic. Copyright © 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Identification of chemicals, possibly originating from misuse of refillable PET bottles, responsible for consumer complaints about off-odours in water and soft drinks.

PubMed

Widén, H; Leufvén, A; Nielsen, T

2005-07-01

Mineral water and soft drinks with a perceptible off-odour were analysed to identify contaminants originating from previous misuse of the refillable polyethylene terephthalate (PET) bottle. Consumers detected the off-odour after opening the bottle and duly returned it with the remaining content to the producers. The contaminants in question had thus been undetected by the in-line detection devices (so-called 'sniffers') that are supposed to reject misused bottles. GC-MS analysis was carried out on the headspace of 31 returned products and their corresponding reference products, and chromatograms were compared to find the possible off-odour compounds. Substances believed to be responsible for the organoleptic change were 2-methoxynaphthalene (10 bottles), dimethyl disulfide (4), anethole (3), petroleum products (4), ethanol with isoamyl alcohol (1) and a series of ethers (1). The mouldy/musty odour (5 bottles) was caused by trichloroanisole in one instance. In some cases, the origins of the off-odours are believed to be previous consumer misuse of food products (liquorice-flavoured alcohol, home-made alcohol containing fusel oil) or non-food products (cleaning products, petroleum products, oral moist snuff and others). The results also apply to 1.5-litre recyclable PET bottles, since the nature and extent of consumer misuse can be expected to be similar for the two bottle types.

Dengue virus in sub-tropical northern and central Viet Nam: population immunity and climate shape patterns of viral invasion and maintenance.

PubMed

Rabaa, Maia A; Simmons, Cameron P; Fox, Annette; Le, Mai Quynh; Nguyen, Thuy Thi Thu; Le, Hai Yen; Gibbons, Robert V; Nguyen, Xuyen Thanh; Holmes, Edward C; Aaskov, John G

2013-01-01

Dengue virus transmission occurs in both epidemic and endemic cycles across tropical and sub-tropical regions of the world. Incidence is particularly high in much of Southeast Asia, where hyperendemic transmission plagues both urban and rural populations. However, endemicity has not been established in some areas with climates that may not support year-round viral transmission. An understanding of how dengue viruses (DENV) enter these environments and whether the viruses persist in inapparent local transmission cycles is central to understanding how dengue emerges in areas at the margins of endemic transmission. Dengue is highly endemic in tropical southern Vietnam, while increasingly large seasonal epidemics have occurred in northern Viet Nam over the last decade. We have investigated the spread of DENV-1 throughout Vietnam to determine the routes by which the virus enters northern and central regions of the country. Phylogeographic analysis of 1,765 envelope (E) gene sequences from Southeast Asia revealed frequent movement of DENV between neighboring human populations and strong local clustering of viral lineages. Long-distance migration of DENV between human population centers also occurred regularly and on short time-scales, indicating human-mediated viral invasion into northern Vietnam. Human populations in southern Vietnam were found to be the primary source of DENV circulating throughout the country, while central and northern Vietnam acted as sink populations, likely due to reduced connectedness to other populations in the case of the central regions and to the influence of temperature variability on DENV replication and vector survival and competence in the north. Finally, phylogeographic analyses suggested that viral movement follows a gravity model and indicates that population immunity and physical and economic connections between populations may play important roles in shaping patterns of DENV transmission.

Dengue Virus in Sub-tropical Northern and Central Viet Nam: Population Immunity and Climate Shape Patterns of Viral Invasion and Maintenance

PubMed Central

Rabaa, Maia A.; Simmons, Cameron P.; Fox, Annette; Le, Mai Quynh; Nguyen, Thuy Thi Thu; Le, Hai Yen; Gibbons, Robert V.; Nguyen, Xuyen Thanh; Holmes, Edward C.; Aaskov, John G.

2013-01-01

Dengue virus transmission occurs in both epidemic and endemic cycles across tropical and sub-tropical regions of the world. Incidence is particularly high in much of Southeast Asia, where hyperendemic transmission plagues both urban and rural populations. However, endemicity has not been established in some areas with climates that may not support year-round viral transmission. An understanding of how dengue viruses (DENV) enter these environments and whether the viruses persist in inapparent local transmission cycles is central to understanding how dengue emerges in areas at the margins of endemic transmission. Dengue is highly endemic in tropical southern Vietnam, while increasingly large seasonal epidemics have occurred in northern Viet Nam over the last decade. We have investigated the spread of DENV-1 throughout Vietnam to determine the routes by which the virus enters northern and central regions of the country. Phylogeographic analysis of 1,765 envelope (E) gene sequences from Southeast Asia revealed frequent movement of DENV between neighboring human populations and strong local clustering of viral lineages. Long-distance migration of DENV between human population centers also occurred regularly and on short time-scales, indicating human-mediated viral invasion into northern Vietnam. Human populations in southern Vietnam were found to be the primary source of DENV circulating throughout the country, while central and northern Vietnam acted as sink populations, likely due to reduced connectedness to other populations in the case of the central regions and to the influence of temperature variability on DENV replication and vector survival and competence in the north. Finally, phylogeographic analyses suggested that viral movement follows a gravity model and indicates that population immunity and physical and economic connections between populations may play important roles in shaping patterns of DENV transmission. PMID:24340118

19. MOLTEN IRON FLOWS INTO A 'BOTTLE' AT FURNACE NO. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. MOLTEN IRON FLOWS INTO A 'BOTTLE' AT FURNACE NO. 1. THE IRON WILL BE TRANSPORTED BY RAIL TO THE OPEN HEARTH OR BASIC OXYGEN FURNACES, WHERE IT IS A MAJOR COMPONENT IN THE PRODUCTION OF STEEL. - Corrigan, McKinney Steel Company, 3100 East Forty-fifth Street, Cleveland, Cuyahoga County, OH

Stability of extemporaneously compounded dexamethasone in glass and plastic bottles and plastic syringes.

PubMed

Ensom, Mary H H; Décarie, Diane

2014-07-01

Dexamethasone is widely used to treat rheumatic and endocrine disorders and chemotherapy-induced nausea and vomiting. A palatable, alcohol-free liquid formulation, with a suitable concentration to allow reasonable administration volume, is available only via extemporaneous compounding. To evaluate the stability of dexamethasone suspensions in commercially available vehicles (Oral Mix and Oral Mix SF) in various types of containers after storage at 25°C and 4°C for up to 91 days. Dexamethasone suspensions (1 mg/mL) were prepared in Oral Mix and Oral Mix SF and then transferred to amber glass and plastic prescription bottles and plastic oral syringes. Suspensions in all 3 types of containers were stored at 25°C; suspensions in glass and plastic bottles were also stored at 4°C. Samples were collected weekly from each container up to 28 days and then every 2 weeks up to 91 days. The samples were analyzed by a validated, stability-indicating high-performance liquid chromatography - ultraviolet detection method. A suspension was considered stable if it maintained at least 90% of its initial dexamethasone concentration. Changes in colour, taste, odour, precipitation (and ease of resuspension), and pH were used to assess physical compatibility. All suspensions maintained at least 96% of the original concentration for up to 91 days with storage at 25°C or at 4°C. No notable changes in colour, taste, odour, precipitation, or pH were observed over the 91-day period. Dexamethasone suspensions (1 mg/mL) in Oral Mix and Oral Mix SF, stored in amber glass or plastic bottles or plastic syringes at 25°C or in amber glass or plastic bottles at 4°C can be expected to remain stable for up to 91 days.

Stability of Extemporaneously Compounded Dexamethasone in Glass and Plastic Bottles and Plastic Syringes

PubMed Central

Ensom, Mary H H; Décarie, Diane

2014-01-01

Background Dexamethasone is widely used to treat rheumatic and endocrine disorders and chemotherapy-induced nausea and vomiting. A palatable, alcohol-free liquid formulation, with a suitable concentration to allow reasonable administration volume, is available only via extemporaneous compounding. Objective: To evaluate the stability of dexamethasone suspensions in commercially available vehicles (Oral Mix and Oral Mix SF) in various types of containers after storage at 25°C and 4°C for up to 91 days. Methods: Dexamethasone suspensions (1 mg/mL) were prepared in Oral Mix and Oral Mix SF and then transferred to amber glass and plastic prescription bottles and plastic oral syringes. Suspensions in all 3 types of containers were stored at 25°C; suspensions in glass and plastic bottles were also stored at 4°C. Samples were collected weekly from each container up to 28 days and then every 2 weeks up to 91 days. The samples were analyzed by a validated, stability-indicating high-performance liquid chromatography − ultraviolet detection method. A suspension was considered stable if it maintained at least 90% of its initial dexamethasone concentration. Changes in colour, taste, odour, precipitation (and ease of resuspension), and pH were used to assess physical compatibility. Results: All suspensions maintained at least 96% of the original concentration for up to 91 days with storage at 25°C or at 4°C. No notable changes in colour, taste, odour, precipitation, or pH were observed over the 91-day period. Conclusion: Dexamethasone suspensions (1 mg/mL) in Oral Mix and Oral Mix SF, stored in amber glass or plastic bottles or plastic syringes at 25°C or in amber glass or plastic bottles at 4°C can be expected to remain stable for up to 91 days. PMID:25214658

Some bottled water may be salubrious.

PubMed

Klevay, Leslie M

2018-07-01

Hard drinking water seems protective against cardiovascular disease compared to soft water. Published data on calcium and magnesium in bottled water products were evaluated to determine water hardness. Data on water chemistry of thirty-three products were obtained from the internet and hardness, as calcium carbonate, was calculated. Approximately two thirds of the products were soft according to criteria of the US Geological Survey; only one fifth were very hard. Beer and wine also were found to be very hard. Consumers and suppliers should avoid soft water. Some beneficial, cardiovascular effects of beer and wine may be the result of hard water. Copyright © 2018 Elsevier GmbH. All rights reserved.

Platelets in blood stored in untreated and siliconed glass bottles and plastic bags

PubMed Central

Kissmeyer-Nielsen, F.; Madsen, C. B.; Nedergaard, Jytte

1961-01-01

Platelet survival was determined using untreated and siliconed glass bottles and plastic bags (Fenwal) for collecting and storing blood. The platelets were tagged in vivo with P32 in six polycythaemic patients undergoing treatment with P32. The results showed that fresh ACD blood collected in untreated glass, siliconed glass, and plastic gave the same recovery of platelets in the recipients. The use of EDTA (Fenwal formula) as anticoagulant gave results inferior to those obtained with blood using ACD as anticoagulant. Even after storage up to 24 hours in untreated glass bottles (ordinary bank blood) a satisfactory recovery of platelets was observed. After storage for 72 hours the recovery was less but not negligible. PMID:14456481

Baby bottle steam sterilizers for disinfecting home nebulizers inoculated with non-tuberculous mycobacteria.

PubMed

Towle, D; Callan, D A; Lamprea, C; Murray, T S

2016-03-01

Non-tuberculous mycobacteria (NTMb), present in environmental water sources, can contribute to respiratory infection in patients with chronic pulmonary disease. Contaminated nebulizers are a potential source of respiratory infection. Treatment with baby bottle steam sterilizers disinfects home nebulizers inoculated with bacterial pathogens but whether this method works for disinfection of NTMb is unclear. Baby bottle steam sterilization was compared with vigorous water washing for disinfecting home nebulizers inoculated with NTMb mixed with cystic fibrosis sputum. No NTMb was recovered from any nebulizers after steam treatment whereas viable NTMb grew after water washing, demonstrating that steam sterilization effectively disinfects NTMb-inoculated nebulizers. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

An outbreak of acute gastroenteritis associated with contaminated bottled water in a university - Jiangxi, China, 2012.

PubMed

Wang, Ruiping; Cheng, Huijian; Zong, Jun; Yu, Ping; Fu, Weijie; Yang, Fuqiang; Shi, Guoqing; Zeng, Guang

2012-10-01

On 23 May 2012, a university in Jiangxi, China reported a gastroenteritis outbreak. We investigated the outbreak to identify the agent, source and mode of transmission and to recommend control measures. A case was defined as any person from the university with onset of diarrhoea (≥ 3 times/24h) from 1 to 31 May 2012. Active case finding was conducted by reviewing university hospital and drug-store records and interviewing students, workers and teachers. We then conducted a case-control study in which we compared food, water and environmental exposure history. Water samples were collected and tested. We identified 417 cases - an attack rate (AR) of 4.7% (417/8781) for the university. There were 416 student cases (AR = 5.7%) distributed across all 11 colleges, five of which were more heavily affected (AR range = 5.9-14%). In the case-control study, cases had higher odds of having drunk bottled water (odds ratio [OR] = 4.1; 95% confidence interval [CI] = 1.7-9.9), and there was a dose-response relationship (χ(2)trend = 4.6, P < 0.05). Drinking boiled bottled water was inversely associated with being a case (OR = 0.22, 95% CI = 0.07-0.71). Eating in any of the three university canteens or drinking-water from the city water supply was not associated with being a case. Pathogenic Escherichia coli was isolated from two unopened bottled water specimens and from four student cases. This gastroenteritis outbreak was most likely caused by contaminated bottled water. The company in question has been shut down and no further cases have been reported. Increased regulation of bottled water plants and better coordination between different investigators for future outbreaks is recommended.

Is Your Drinking Water Acidic? A Comparison of the Varied pH of Popular Bottled Waters.

PubMed

Wright, Kellie F

2015-06-01

Dental professionals continually educate patients on the dangers of consuming acidic foods and beverages due to their potential to contribute to dental erosion and tooth decay. Excess acid in the diet can also lead to acidosis, which causes negative systemic side effects. However, water is not typically categorized as acidic. The purpose of this in-vitro study was to investigate the pH levels of several popular brands of bottled water and compare them to various other acidic beverages. Two different brands of marketed alkaline water (with a pH of 8.8 or higher) were also studied, tested for acidity and described. A pilot in-vitro study was conducted to determine the pH levels of a convenience sample of popular brands of bottled water, tap water and other known acidic beverages in comparison with the pH values reported on the respective manufacturers' website. Each beverage was tested in a laboratory using a calibrated Corning pH meter model 240, and waters were compared to the corresponding company's testified pH value. Waters were also compared and contrasted based on their process of purification. The data was then compiled and analyzed descriptively. The pH values for the tested beverages and bottled waters were found to be predominantly acidic. Ten out of the 14 beverages tested were acidic (pH<7), 2 municipal (or "tap") waters were neutral (pH=7) and 2 bottled waters were alkaline (pH>7). The majority of waters tested had a more acidic pH when tested in the lab than the value listed in their water quality reports. It is beneficial for the health care provider to be aware of the potential acidity of popular bottled drinking waters and educate patients accordingly. Copyright © 2015 The American Dental Hygienists’ Association.

Predicting consumer preferences for mineral composition of bottled and tap water.

PubMed

Platikanov, Stefan; Hernández, Alejandra; González, Susana; Luis Cortina, Jose; Tauler, Roma; Devesa, Ricard

2017-01-01

The overall liking for taste of water was correlated with the mineral composition of selected bottled and tap waters. Sixty-nine untrained volunteers assessed and rated twenty-five different commercial bottled and tap waters from. Water samples were physicochemical characterised by analysing conductivity, pH, total dissolved solids (TDS) and major anions and cations: HCO 3 - , SO 4 2- , Cl - , NO 3 - , Ca 2+ , Mg 2+ , Na + , and K + . Residual chlorine levels were also analysed in the tap water samples. Globally, volunteers preferred waters rich in calcium bicarbonate and sulfate, rather than in sodium chloride. This study also demonstrated that it was possible to accurately predict the overall liking by a Partial Least Squares regression using either all measured physicochemical parameters or a reduced number of them. These results were in agreement with previously published results using trained panellists. Copyright © 2016 Elsevier B.V. All rights reserved.

Spark Ignition of Combustible Vapor in a Plastic Bottle as a Demonstration of Rocket Propulsion

NASA Astrophysics Data System (ADS)

Mattox, J. R.

2017-01-01

I report an innovation that provides a compelling demonstration of rocket propulsion, appropriate for students of physics and other physical sciences. An electrical spark is initiated from a distance to cause the deflagration of a combustible vapor mixed with air in a lightweight plastic bottle that is consequently propelled as a rocket by the release of combustion products, i.e., a "whoosh rocket." My recommendation is that the standard fuel for pedagogical whoosh demonstrations be isopropanol, and the recommended vessel is the 3.8-L high-density polyethylene (HDPE) bottle.

Eco-friendly Fibre from Recycled Polypropylene of Bottle Cap Waste and Lignin

NASA Astrophysics Data System (ADS)

Soekoco, A. S.; Basuki, A.; Mardiyati

2016-01-01

Ecofriendly fibre is one of potential alternatives to fulfill the rising demand in textile material supply which is limited due to the decreasing reserve of oil. Large amount of polypropylene waste from bottle cap and lignin as a byproduct from pulp industry are potential solutions. Grinded polypropylene bottle cap was blended with lignin powder in concentration of 5 wt. % processed by melt spinning at 170° C temperature. The fibres produced have an average diameter 170 and 250 micrometres. In view of the mechanical properties. the tensile strength is 11.9 MPa for fibre with 170 micrometres diameter and 14.7 MPa for fibre with 250 micrometres diameter. Fibre surface morphology was further studied using micron microscope. and the result shows black flocks spread in the fibre. indicating that the lignin does not blend evenly.

Water Jets from Bottles, Buckets, Barrels, and Vases with Holes

ERIC Educational Resources Information Center

Lopac, Vjera

2015-01-01

Observation of the water jets flowing from three equidistant holes on the side of a vertical cylindrical bottle is an interesting and widely used didactical experiment illustrating the laws of fluids in motion. In this paper we analyze theoretically and numerically the ranges of the stationary water jets flowing from various rotationally symmetric…

Evaluation of fluoride levels in bottled water and their contribution to health and teeth problems in the United Arab Emirates.

PubMed

Abouleish, Mohamed Yehia Z

2016-10-01

Fluoride is needed for better health, yet if ingested at higher levels it may lead to health problems. Fluoride can be obtained from different sources, with drinking water being a major contributor. In the United Arab Emirates (UAE), bottled water is the major source for drinking. The aim of this research is to measure fluoride levels in different bottled water brands sold in UAE, to determine whether fluoride contributes to better health or health problems. The results were compared to international and local standards. Fluoride was present in seven out of 23 brands. One brand exhibited high fluoride levels, which exceeded all standards, suggesting it may pose health problems. Other brands were either below or above standards, suggesting either contribution to better health or health problems, depending on ingested amount. A risk assessment suggested a potential for non-cancer effects from some brands. The results were compared to fluoride levels in bottled water sold in UAE and neighboring countries (e.g. Saudi Arabia, Qatar, Kuwait, and Bahrain), over 24 years, to reflect on changes in fluoride levels in bottled water in this region. The research presents the need for creating, stricter regulations that require careful fluoride monitoring and new regulations that require listing fluoride level on the bottled water label, internationally and regionally. The research will have local and global health impact, as bottled water sold in UAE and neighboring countries, is produced locally and imported from international countries, e.g. Switzerland, the USA, France, Italy, New Zealand, and Fiji.

One-pot synthesis of molecular bottle-brush functionalized single-walled carbon nanotubes with superior dispersibility in water.

PubMed

Deng, Yong; Hu, Qin; Yuan, Qiulin; Wu, Yan; Ling, Ying; Tang, Haoyu

2014-01-01

Molecular bottle-brush functionalized single-walled carbon nanotubes (SWCNTs) with superior dispersibility in water are prepared by a one-pot synthetic methodology. Elongating the main-chain and side-chain length of molecular bottle-brushes can further increase SWCNT dispersibility. They show significant enhancement of SWCNT dispersibility up to four times higher than those of linear molecular functionalized SWCNTs. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bacteriological quality and risk assessment of the imported and domestic bottled mineral water sold in Fiji.

PubMed

Zeenat, A; Hatha, A A M; Viola, L; Vipra, K

2009-12-01

Considering the popularity of bottled mineral water among indigenous Fijians and tourists alike, a study was carried out to determine the bacteriological quality of different bottled waters. A risk assessment was also carried out. Seventy-five samples of bottled mineral water belonging to three domestic brands and 25 samples of one imported brand were analysed for heterotrophic plate count (HPC) bacteria and faecal coliforms. HPC counts were determined at 22 degrees C and 37 degrees C using R2A medium and a membrane filtration technique was used to determine the faecal coliform (FC) load in 100 ml of water on mFC agar. Between 28 and 68% of the samples of the various domestic brands failed to meet the WHO standard of 100 colony forming units (cfu) per 100 ml at 22 degrees C and 7% of these also tested positive for faecal coliforms. All imported bottled mineral water samples were within WHO standards. A risk assessment of the HPC bacteria was carried out in terms of beta haemolytic activity and antibiotic resistance. More than 50% of the isolates showed beta haemolytic activity and were multi-drug resistant. While the overall quality of the product was generally good, there is a need to enforce stringent quality standards for the domestic bottlers to ensure the safety of consumers.

Bottle feeding and ideology in colonial Malaya: the production of change.

PubMed

Manderson, L

1982-01-01

Considerable attention has been paid to the correlation between high infant morbidity and mortality rates and the increased incidence of bottle feeding. The shift from prolonged breast feeding to a mixed regime or the exclusive use of sweetened condensed milk or infant formula has been related to the promotional activities of milk companies, and typically has been presented as a relatively recent development in Third World countries. However, the marketing of tinned and powdered milk only partially explains the increased use of these products. In colonial Malaya, condensed milk was marketed from the late 19th century. Infant formula was available from the turn of the century and was widely advertised, first in the English-language press and later also in the vernacular presses. At the same time, other social and cultural factors served to discourage breast feeding. There were changes in ideas regarding ideal body weight for both women and infants, and regarding infant care and diet; these ideas were presented in the mass media. In addition, maternal and child health clinics, established in the 1920s to reduce the high infant mortality rate, both propagated popular beliefs about infant weight and supplied milk and educated women to artificially feed their infants. Industry, the media, and health services all promoted, if not always intentionally, bottle feeding rather than breast feeding. Bottle feeding as an ideal, if not a reality, was thus well established before the intensive promotion of milk products by multinational corporations that followed the political independence of the colony.

Migration of antimony from PET bottles into beverages: determination of the activation energy of diffusion and migration modelling compared with literature data.

PubMed

Welle, F; Franz, R

2011-01-01

Plastics bottles made from polyethylene terephthalate (PET) are increasingly used for soft drinks, mineral water, juices and beer. In this study a literature review is presented concerning antimony levels found both in PET materials as well as in foods and food simulants. On the other hand, 67 PET samples from the European bottle market were investigated for their residual antimony concentrations. A mean value of 224 ± 32 mg kg(-1) was found, the median was 220 mg kg(-1). Diffusion coefficients for antimony in PET bottle materials were experimentally determined at different temperature between 105 and 150°C. From these data, the activation energy of diffusion for antimony species from the PET bottle wall into beverages and food simulants was calculated. The obtained value of 189 kJ mol(-1) was found to be in good agreement with published data on PET microwave trays (184 kJ mol(-1)). Based on these results, the migration of antimony into beverages was predicted by mathematical migration modelling for different surface/volume ratios and antimony bottle wall concentrations. The results were compared with literature data as well as international legal limits and guidelines values for drinking water and the migration limit set from food packaging legislation. It was concluded that antimony levels in beverages due to migration from PET bottles manufactured according to the state of the art can never reach or exceed the European-specific migration limit of 40 microg kg(-1). Maximum migration levels caused by room-temperature storage even after 3 years will never be essentially higher than 2.5 microg kg(-1) and in any case will be below the European limit of 5 microg kg(-1) for drinking water. The results of this study confirm that the exposure of the consumer by antimony migration from PET bottles into beverages and even into edible oils reaches approximately 1% of the current tolerable daily intake (TDI) established by World Health Organisation (WHO). Having

Recent advances in molecular biology of parasitic viruses.

PubMed

Banik, Gouri Rani; Stark, Damien; Rashid, Harunor; Ellis, John T

2014-01-01

The numerous protozoa that can inhabit the human gastro-intestinal tract are known, yet little is understood of the viruses which infect these protozoa. The discovery, morphologic details, purification methods of virus-like particles, genome and proteome of the parasitic viruses, Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and the Eimeria sp. are described in this review. The protozoan viruses share many common features: most of them are RNA or double-stranded RNA viruses, ranging between 5 and 8 kilobases, and are spherical or icosahedral in shape with an average diameter of 30-40 nm. These viruses may influence the function and pathogenicity of the protozoa which they infect, and may be important to investigate from a clinical perspective. The viruses may be used as specific genetic transfection vectors for the parasites and may represent a research tool. This review provides an overview on recent advances in the field of protozoan viruses.

Fluoride content in bottled waters, juices and carbonated soft drinks in Mexico City, Mexico.

PubMed

Jimenez-Farfan, M D; Hernandez-Guerrero, J C; Loyola-Rodriguez, J P; Ledesma-Montes, C

2004-07-01

The objective of this study was to analyse 283 samples of soft drinks available in the metropolitan market of Mexico City, Mexico: 105 juices, 101 nectars, 57 carbonated drinks and 20 bottled waters. Samples of the beverages were analysed using an Orion 720A potentiometer and an Orion 9609BN F ion-specific electrode. Fluoride concentration in the above-mentioned products ranged from 0.07 to 1.42 p.p.m. It was found that fluoride concentrations varied according to the brand, flavour and presentation of the product. The highest mean concentration of fluoride was found in the juices and cola drinks (0.67 +/- 0.38 and 0.49 +/- 0.41 p.p.m., respectively). The mean fluoride concentration for carbonated drinks was 0.43 +/- 0.36 p.p.m. Bottled waters had a fluoride concentration of 0.21 +/- 0.08 p.p.m. The findings suggest that fluoride ingested through bottled drinks represents an important part of the total fluoride ingested by the population. In view of the wide variation of fluoride concentration in the tested products, it is necessary to implement regulatory guidelines for controlling its concentration in order to prevent dental fluorosis.

[Experimental monkey encephalitis caused by Powassan virus].

PubMed

Frolova, M P; Isachkova, L M; Shestopalova, N M; Pogodina, V V

1981-01-01

A comparative study of the experimental infection of monkeys caused by brain P-40 of Powassan virus isolated in the Primorye Territory of the USSR and by the prototype Canadian strain LB was carried out. Powassan virus was found to be pathogenic for Macaca rhesus. Clinical and pathomorphological picture of the experimental encephalitis was studied. Full identity of the infection caused in the monkeys by the strain P-40 and the Canadian strain LB of Powassan virus has been proved. On electronmicroscopic examination of the central nervous system the virus was detected in the neurons, glial cells and intercellular spaces. The virions of the strains studied have identical morphological parameters, being 37 to 45 nm in diameter and having spherical shape. The data obtained point to a marked neurotropism of the virus. They will contribute to elucidation of the virus role in the infectious pathology of man, and namely, in verification of encephalitis cases not associated etiologically with the virus of the spring-summer tick-borne encephalitis.

Within-Host Evolution of Human Influenza Virus.

PubMed

Xue, Katherine S; Moncla, Louise H; Bedford, Trevor; Bloom, Jesse D

2018-03-10

The rapid global evolution of influenza virus begins with mutations that arise de novo in individual infections, but little is known about how evolution occurs within hosts. We review recent progress in understanding how and why influenza viruses evolve within human hosts. Advances in deep sequencing make it possible to measure within-host genetic diversity in both acute and chronic influenza infections. Factors like antigenic selection, antiviral treatment, tissue specificity, spatial structure, and multiplicity of infection may affect how influenza viruses evolve within human hosts. Studies of within-host evolution can contribute to our understanding of the evolutionary and epidemiological factors that shape influenza virus's global evolution. Copyright © 2018 Elsevier Ltd. All rights reserved.

Bottle Babies: A Guide to the Baby Foods Issue. Revised.

ERIC Educational Resources Information Center

Cottingham, Jane, Comp.

This guide has been compiled as an aide-memoire and resource book about the increasing incidence of malnutrition in infants caused by bottle feeding in the Third World. It deals with four major interrelated issues: (1) the prevalence of protein energy malnutrition, (2) the importance of breast milk, not only in preventing malnutrition and disease…

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

DOE PAGES

Pattie. Jr., Robert Wayne; Adamek, Evan Robert; Brenner, Thomas; ...

2017-08-10

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50μm thick NiP coatings on stainless steel and aluminum substrates was measured to be V F=213(5.2)neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle wasmore » interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1.3(1)×10 –4. In conclusion, we also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.« less

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

NASA Astrophysics Data System (ADS)

Pattie, R. W.; Adamek, E. R.; Brenner, T.; Brandt, A.; Broussard, L. J.; Callahan, N. B.; Clayton, S. M.; Cude-Woods, C.; Currie, S. A.; Geltenbort, P.; Ito, T. M.; Lauer, T.; Liu, C. Y.; Majewski, J.; Makela, M.; Masuda, Y.; Morris, C. L.; Ramsey, J. C.; Salvat, D. J.; Saunders, A.; Schroffenegger, J.; Tang, Z.; Wei, W.; Wang, Z.; Watkins, E.; Young, A. R.; Zeck, B. A.

2017-11-01

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50 μm thick NiP coatings on stainless steel and aluminum substrates was measured to be VF = 213(5 . 2) neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle was interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1 . 3(1) × 10-4. We also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.

Evaluation of commercial nickel-phosphorus coating for ultracold neutron guides using a pinhole bottling method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pattie. Jr., Robert Wayne; Adamek, Evan Robert; Brenner, Thomas

We report on the evaluation of commercial electroless nickel phosphorus (NiP) coatings for ultracold neutron (UCN) transport and storage. The material potential of 50μm thick NiP coatings on stainless steel and aluminum substrates was measured to be V F=213(5.2)neV using the time-of-flight spectrometer ASTERIX at the Lujan Center. The loss per bounce probability was measured in pinhole bottling experiments carried out at ultracold neutron sources at Los Alamos Neutron Science Center and the Institut Laue-Langevin. For these tests a new guide coupling design was used to minimize gaps between the guide sections. The observed UCN loss in the bottle wasmore » interpreted in terms of an energy independent effective loss per bounce, which is the appropriate model when gaps in the system and upscattering are the dominate loss mechanisms, yielding a loss per bounce of 1.3(1)×10 –4. In conclusion, we also present a detailed discussion of the pinhole bottling methodology and an energy dependent analysis of the experimental results.« less

Is container type the biggest predictor of trace element and BPA leaching from drinking water bottles?

PubMed

Rowell, Candace; Kuiper, Nora; Preud'Homme, Hugues

2016-07-01

The knowledge-base of bottled water leachate is highly contradictory due to varying methodologies and limited multi-elemental and/or molecular analyses; understanding the range of contaminants and their pathways is required. This study determined the leaching potential and leaching kinetics of trace elements, using consistent comprehensive quantitative and semi-quantitative (79 elements total) analyses, and BPA, using isotopic dilution and MEPS pre-concentration with UHPLC-ESI-QTOF. Statistical methods were used to determine confounders and predictors of leaching and human health risk throughout 12days of UV exposure and after exposure to elevated temperature. Various types of water were used to assess the impact of water quality. Results suggest Sb leaching is primarily dependent upon water quality, not container type. Bottle type is a predictor of elemental leaching for Pb, Ba, Cr, Cu, Mn and Sr; BPA was detected in samples from polycarbonate containers. Health risks from the consumption of bottled water increase after UV exposure. Copyright © 2016 Elsevier Ltd. All rights reserved.

Standardization and assessment of cell culture media quantities in roller poly ethylene terephthalate bottles employed in the industrial rabies viral vaccine production.

PubMed

Jagannathan, S; Chaansha, S; Rajesh, K; Santhiya, T; Charles, C; Venkataramana, K N

2009-09-15

Vero cells are utilized for production of rabies vaccine. This study deals with the optimize quantity media require for the rabies vaccine production in the smooth roller surface. The rabies virus (Pasteur vaccine strain) is infected to monolayer of the various experimented bottles. To analyze the optimal quantity of media for the production of rabies viral harvest during the process of Vero cell derived rabies vaccine. The trials are started from 200 to 400 mL (PTARV-1, PTARV-2, PTARV-3, PTARV-4 and PTARV-5). The samples are taken in an appropriate time intervals for analysis of In Process Quality Control (IPQC) tests. The collected viral harvests are further processed to rabies vaccine in a pilot level and in addition to scale up an industrial level. Based on the evaluation the PTARV-2 (250 mL) show highly encouraging results for the Vero cell derived rabies vaccine production.

A comparative study of digital RT-PCR and RT-qPCR for quantification of Hepatitis A virus and Norovirus in lettuce and water samples.

PubMed

Coudray-Meunier, Coralie; Fraisse, Audrey; Martin-Latil, Sandra; Guillier, Laurent; Delannoy, Sabine; Fach, Patrick; Perelle, Sylvie

2015-05-18

Sensitive and quantitative detection of foodborne enteric viruses is classically achieved by quantitative RT-PCR (RT-qPCR). Recently, digital PCR (dPCR) was described as a novel approach to genome quantification without need for a standard curve. The performance of microfluidic digital RT-PCR (RT-dPCR) was compared to RT-qPCR for detecting the main viruses responsible for foodborne outbreaks (human Noroviruses (NoV) and Hepatitis A virus (HAV)) in spiked lettuce and bottled water. Two process controls (Mengovirus and Murine Norovirus) were used and external amplification controls (EAC) were added to examine inhibition of RT-qPCR and RT-dPCR. For detecting viral RNA and cDNA, the sensitivity of the RT-dPCR assays was either comparable to that of RT-qPCR (RNA of HAV, NoV GI, Mengovirus) or slightly (around 1 log10) decreased (NoV GII and MNV-1 RNA and of HAV, NoV GI, NoV GII cDNA). The number of genomic copies determined by dPCR was always from 0.4 to 1.7 log10 lower than the expected numbers of copies calculated by using the standard qPCR curve. Viral recoveries calculated by RT-dPCR were found to be significantly higher than by RT-qPCR for NoV GI, HAV and Mengovirus in water, and for NoV GII and HAV in lettuce samples. The RT-dPCR assay proved to be more tolerant to inhibitory substances present in lettuce samples. This absolute quantitation approach may be useful to standardize quantification of enteric viruses in bottled water and lettuce samples and may be extended to quantifying other human pathogens in food samples. Copyright © 2015 Elsevier B.V. All rights reserved.

A More Perfect Commodity: Bottled Water, Global Accumulation, and Local Contestation

ERIC Educational Resources Information Center

Jaffee, Daniel; Newman, Soren

2013-01-01

Bottled water sits at the intersection of debates regarding the social and environmental effects of the commodification of nature and the ways neoliberal globalization alters the provision of public services. Utilizing Polanyi's concept of fictitious commodities and Harvey's work on accumulation by dispossession, this article traces bottled…

[Breast-feeding, bottle-feeding, sucking habits and malocclusion in Brazilian preschool children].

PubMed

Leite-Cavalcanti, Alessandro; Medeiros-Bezerra, Priscila K; Moura, Cristiano

2007-01-01

This study was aimed at verifying the prevalence of nutritive (breast-feeding and bottle-feeding) and non-nutritive sucking habits and the presence of malocclusion in Brazilian preschool children. The study was a cross-sectional oral health survey of 342 children (196 boys and 146 girls) between the ages of 3 and 5 in Campina Grande, Brazil. The data was collected by interviews with the children's mothers or minders and by clinical examinations carried out by a calibrated examiner (kappa = 0,86). Descriptive statistics using the EPI-INFO Program (version 3.3) and Chi-square test at 0.05 probability level were produced. Sucking habit prevalence was very high in all groups, ranging from 70 % to 77,4 %. Malocclusion was present in 87 %, dummy use in 84,8 % and finger-sucking in 7,2 %. About 84,2 % of the children had a history of bottle-feeding and 79,9 % showed some evidence of malocclusion at the time of dental examination. There were significant differences for the following variables: sucking habits and malocclusion; breast-feeding time and sucking habits; breast-feeding time and malocclusion; type of feeding and sucking habits; and type of feeding and malocclusion. Dummy-sucking incidence was higher than that of finger-sucking in Brazilian children. Sucking habit incidence was higher in bottle-fed children than in breast-fed children. The relationship between incidence of habits and malocclusion was statistically significant.

Simultaneous Sterilization With Surface Modification Of Plastic Bottle By Plasma-Based Ion Implantation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sakudo, N.; Ikenaga, N.; Ikeda, F.

2011-01-07

Dry sterilization of polymeric material is developed. The technique utilizes the plasma-based ion implantation which is same as for surface modification of polymers. Experimental data for sterilization are obtained by using spores of Bacillus subtilis as samples. On the other hand we previously showed that the surface modification enhanced the gas barrier characteristics of plastic bottles. Comparing the implantation conditions for the sterilization experiment with those for the surface modification, we find that both sterilization and surface modification are simultaneously performed in a certain range of implantation conditions. This implies that the present bottling system for plastic vessels will bemore » simplified and streamlined by excluding the toxic peroxide water that has been used in the traditional sterilization processes.« less

Respiratory symptoms among glass bottle workers--cough and airways irritancy syndrome?

PubMed

Gordon, S B; Curran, A D; Fishwick, D; Morice, A H; Howard, P

1998-10-01

Glass bottle workers have been shown to experience an excess of respiratory symptoms. This work describes in detail the symptoms reported by a cohort of 69 symptomatic glass bottle workers. Symptoms, employment history and clinical investigations including radiology, spirometry and serial peak expiratory flow rate records were retrospectively analyzed from clinical records. The results showed a consistent syndrome of work-related eye, nose and throat irritation followed after a variable period by shortness of breath. The latent interval between starting work and first developing symptoms was typically 4 years (median = 4 yrs; range = 0-28). The interval preceding the development of dysponea was longer and much more variable (median = 16 yrs; range = 3-40). Spirometry was not markedly abnormal in the group but 57% of workers had abnormal serial peak expiratory flow rate charts. Workers in this industry experience upper and lower respiratory tract symptoms consistent with irritant exposure. The long-term functional significance of these symptoms should be formally investigated.

From Baby Bottle to Cup: Choose Training Cups Carefully, Use Them Temporarily

MedlinePlus

... early childhood caries (some- times called “baby bottle tooth decay”) is frequent and prolonged exposure of a baby’s ... including milk and juice drinks), because that encourages tooth decay. Offer these liquids only at mealtimes—understanding that ...

49 CFR 192.177 - Additional provisions for bottle-type holders.

Code of Federal Regulations, 2011 CFR

2011-10-01

... in accordance with § 192.327. (b) Each bottle-type holder manufactured from steel that is not... steel must meet the chemical and tensile requirements for the various grades of steel in ASTM A 372/A 372M. (2) The actual yield-tensile ratio of the steel may not exceed 0.85. (3) Welding may not be...

49 CFR 192.177 - Additional provisions for bottle-type holders.

Code of Federal Regulations, 2010 CFR

2010-10-01

... in accordance with § 192.327. (b) Each bottle-type holder manufactured from steel that is not... steel must meet the chemical and tensile requirements for the various grades of steel in ASTM A 372/A 372M. (2) The actual yield-tensile ratio of the steel may not exceed 0.85. (3) Welding may not be...

Comparative life cycle assessment and life cycle costing of four disposal scenarios for used polyethylene terephthalate bottles in Mauritius.

PubMed

Foolmaun, Rajendra Kumar; Ramjeeawon, Toolseeram

2012-09-01

The annual rise in population growth coupled with the flourishing tourism industry in Mauritius has lead to a considerable increase in the amount of solid waste generated. In parallel, the disposal of non-biodegradable wastes, especially plastic packaging and plastic bottles, has also shown a steady rise. Improper disposal of used polyethylene terephthalate (PET) bottles constitutes an eyesore to the environmental landscape and is a threat to the flourishing tourism industry. It is of utmost importance, therefore, to determine a suitable disposal method for used PET bottles which is not only environmentally efficient but is also cost effective. This study investigated the environmental impacts and the cost effectiveness of four selected disposal alternatives for used PET bottles in Mauritius. The four disposal routes investigated were: 100% landfilling; 75% incineration with energy recovery and 25% landfilling; 40% flake production (partial recycling) and 60% landfilling; and 75% flake production and 25% landfilling. Environmental impacts of the disposal alternatives were determined using ISO standardized life cycle assessment (LCA) and with the support of SimaPro 7.1 software. Cost effectiveness was determined using life cycle costing (LCC). Collected data were entered into a constructed Excel-based model to calculate the different cost categories, Net present values, damage costs and payback periods. LCA and LCC results indicated that 75% flake production and 25% landfilling was the most environmentally efficient and cost-effective disposal route for used PET bottles in Mauritius.

Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons

PubMed Central

Le, Hoa H.; Carlson, Emily M.; Chua, Jason P.; Belcher, Scott M.

2008-01-01

The impact of endocrine disrupting chemical (EDC) exposure on human health is receiving increasingly focused attention. The prototypical EDC bisphenol A (BPA) is an estrogenic high-production chemical used primarily as a monomer for production of polycarbonate and epoxy resins. It is now well established that there is ubiquitous human exposure to BPA. In the general population exposure to BPA occurs mainly by consumption of contaminated foods and beverages that have contacted epoxy resins or polycarbonate plastics. To test the hypothesis that bioactive BPA was released from polycarbonate bottles used for consumption of water and other beverages, we evaluated whether BPA migrated into water stored in new or used high-quality polycarbonate bottles used by consumers. Using a sensitive and quantitative competitive enzyme-linked immunosorbent assay, BPA was found to migrate from polycarbonate water bottles at rates ranging from 0.20 to 0.79 ng per hour. At room temperature the migration of BPA was independent of whether or not the bottle had been previously used. Exposure to boiling water (100°C) increased the rate of BPA migration by up to 55-fold. The estrogenic bioactivity of the BPA-like immunoreactivity released into the water samples was confirmed using an in vitro assay of rapid estrogen-signaling and neurotoxicity in developing cerebellar neurons. The amounts of BPA found to migrate from polycarbonate drinking bottles should be considered as a contributing source to the total “EDC-burden” to which some individuals are exposed. PMID:18155859

Evaluation of the Giggenbach bottle method using artificial fumarolic gases

NASA Astrophysics Data System (ADS)

Lee, S.; Jeong, H. Y.

2013-12-01

Volcanic eruption is one of the most dangerous natural disasters. Mt. Baekdu, located on the border between North Korea and China, has been recently showing multiple signs of its eruption. The magmatic activity of a volcano strongly affects the composition of volcanic gases, which can provide a useful tool for predicting the eruption. Among various volcanic gas monitoring methods, the Giggenbach bottle method involves the on-site sampling of volcanic gases and the subsequent laboratory analysis, thus making it possible to detect a range of volcanic gases at low levels. In this study, we aim to evaluate the effectiveness of the Giggenbach bottle method and develop the associated analytical tools using artificial fumarolic gases with known compositions. The artificial fumarolic gases are generated by mixing CO2, CO, H2S, SO2, Ar, and H2 gas streams with a N2 stream sparged through an acidic medium containing HCl and HF. The target compositions of the fumarolic gases are selected to cover those reported for various volcanoes under different tectonic environments as follows: CO2 (2-12 mol %), CO (0.3-1 mol %), H2S (0.7-2 mol %), SO2 (0.6-4 mol %), Ar (0.3-0.7 mol %), H2 (0.3-0.7 mol %), HCl (0.2-1 mol %), and HF (< 0.015 mol %). The artificial fumarolic gases are collected into an evacuated bottle partially filled with 4 M NaOH solution containing 0.5 mM Cd(CH3COO)2. While non-condensable components such as CO, Ar, H2, and N2 accumulate in the headspace of the bottle, acidic components including CO2, SO2, HCl, and HF dissolve into the alkaline solution. In case of H2S, it reacts with dissolved Cd2+ to precipitate as CdS(s). The gas accumulated in the headspace can be analyzed for CO, Ar, H2, and N2 on a gas chromatography. The alkaline solution is first separated from yellowish CdS precipitates by filtration, and then pretreated with hydrogen peroxide to oxidize dissolved SO2 (H2SO3) to SO42-. The resultant solution can be analyzed for SO2 as SO42-, HCl as Cl-, and HF

Comparison of the structures of three circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus.

PubMed

Crowther, R A; Berriman, J A; Curran, W L; Allan, G M; Todd, D

2003-12-01

Circoviruses are small, nonenveloped icosahedral animal viruses characterized by circular single-stranded DNA genomes. Their genomes are the smallest possessed by animal viruses. Infections with circoviruses, which can lead to economically important diseases, frequently result in virus-induced damage to lymphoid tissue and immunosuppression. Within the family Circoviridae, different genera are distinguished by differences in genomic organization. Thus, Chicken anemia virus is in the genus Gyrovirus, while porcine circoviruses and Beak and feather disease virus belong to the genus CIRCOVIRUS: Little is known about the structures of circoviruses. Accordingly, we investigated the structures of these three viruses with a view to determining whether they are related. Three-dimensional maps computed from electron micrographs showed that all three viruses have a T=1 organization with capsids formed from 60 subunits. Porcine circovirus type 2 and beak and feather disease virus show similar capsid structures with flat pentameric morphological units, whereas chicken anemia virus has stikingly different protruding pentagonal trumpet-shaped units. It thus appears that the structures of viruses in the same genus are related but that those of viruses in different genera are unrelated.

Dose-response relationships in a microneutralization test for foot-and-mouth disease viruses.

PubMed Central

Booth, J. C.; Rweyemamu, M. M.; Pay, T. W.

1978-01-01

Two-dimensional quantal microneutralization tests on foot-and-mouth disease viruses, in which neutralizing antibody activity was titrated against a serial range of virus doses, demonstrated a variety of dose-response curves some of which were rectilinear, others clearly curvilinear. Moreover, in the case of the non-linear responses obtained with some antisera, the shape of the curve was such that antibody titres recorded with doses of virus ranging from 10(3)-10(5) TCD50 were closely similar. Studies were carried out on the effect of varying the conditions of the test on the shape of the dose-response curve: significant differences were obtained after treatment of the antiserum-virus mixtures with anti-species globulin, and when the test was assayed in cells of differing susceptibility to infection. PMID:202650

Barley stripe mosaic virus: Structure and relationship to the tobamoviruses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kendall, Amy; Williams, Dewight; Bian, Wen

Barley stripe mosaic virus (BSMV) is the type member of the genus Hordeivirus, rigid, rod-shaped viruses in the family Virgaviridae. We have used fiber diffraction and cryo-electron microscopy to determine the helical symmetry of BSMV to be 23.2 subunits per turn of the viral helix, and to obtain a low-resolution model of the virus by helical reconstruction methods. Features in the model support a structural relationship between the coat proteins of the hordeiviruses and the tobamoviruses. - Highlights: • We report a low-resolution structure of barley stripe mosaic virus. • Barley stripe mosaic virus has 23.2 subunits per turn ofmore » the viral helix. • We compare barley stripe mosaic virus with tobacco mosaic virus.« less

High-Q Hybrid Plasmon-Photon Modes in a Bottle Resonator Realized with a Silver-Coated Glass Fiber with a Varying Diameter

NASA Astrophysics Data System (ADS)

Rottler, Andreas; Harland, Malte; Bröll, Markus; Klingbeil, Matthias; Ehlermann, Jens; Mendach, Stefan

2013-12-01

We experimentally demonstrate that hybrid plasmon-photon modes exist in a silver-coated glass bottle resonator. The bottle resonator is realized in a glass fiber with a smoothly varying diameter, which is subsequently coated with a rhodamine 800-dye doped acryl-glass layer and a 30 nm thick silver layer. We show by means of photoluminescence experiments supported by electromagnetic simulations that the rhodamine 800 photoluminescence excites hybrid plasmon-photon modes in such a bottle resonator, which provide a plasmon-type field enhancement at the outer silver surface and exhibit quality factors as high as 1000.

Field comparison of solar water disinfection (SODIS) efficacy between glass and polyethylene terephalate (PET) plastic bottles under sub-Saharan weather conditions.

PubMed

Asiimwe, J K; Quilty, B; Muyanja, C K; McGuigan, K G

2013-12-01

Concerns about photodegradation products leaching from plastic bottle material into water during solar water disinfection (SODIS) are a major psychological barrier to increased uptake of SODIS. In this study, a comparison of SODIS efficacy using glass and plastic polyethylene terephalate (PET) bottles was carried out under strong real sunlight and overcast weather conditions at Makerere University in central Uganda. Both clear and turbid natural water samples from shallow wells and open dug wells, respectively, were used. Efficacy was determined from the inactivation of a wild strain of Escherichia coli in solar-exposed contaminated water in both glass and PET bottles. The studies reveal no significant difference in SODIS inactivation between glass and PET bottles (95% CI, p > 0.05), for all water samples under the different weather conditions except for clear water under overcast conditions where there was a small but significant difference (95% CI, p = 0.047) with less viable bacterial counts in PET bottles at two intermediate time points but not at the end of the exposure. The results demonstrate that SODIS efficacy in glass under tropical field conditions is comparable to PET plastic. SODIS users in these regions can choose either of reactors depending on availability and preference of the user.

Characterization of crystallinity in PET bottles by IR spectroscopy

NASA Astrophysics Data System (ADS)

Nguyen, Tuan Q.; Christopher, Plummer J. G.

2000-03-01

PET is a semicrystalline thermoplastic widely used to package foods and beverages. Most of these applications rely on the barrier properties of the polymer, which improve with the proportion of crystalline phase. It is therefore important for the industries concerned to develop a fast, simple and reliable technique to quantify the degree of crystallization. Current FTIR and Raman spectroscopy correlate cristallinity with the trans to gauche ratio of the ethylene conformational isomers. Such a procedure, however, is based on the naive assumption that the proportion of trans isomers in the crystalline regions and that of the trans/gauche isomers in the amorphous regions vary linearly with the total crystallinity. By combining density measurements with DSC, WAXS and FTIR, we have shown the conformer technique to work well for isotropic PET sheets, but not for bottles. Biaxial extension of the preform during processing results in strain-induced cristallinity with a different morphology to that induced thermally. As a result, PET should be treated as a three-component mixture with distinct physical and spectroscopic properties for each phase. Using ATR, micro-transmission FTIR and factor analysis, our primary goal has been to develop a routine technique which allows one to identify the contribution of each component in the spectra of commercial PET bottles.

Experimentally Guided Models Reveal Replication Principles that Shape the Mutation Distribution of RNA Viruses

DTIC Science & Technology

2015-01-30

intracel- lular replication. Two classic replication modes have been described for single-stranded RNA viruses: the ‘stamping machine’ mode ( Stent ...Journal of Theoretical Biology 218:309–321. doi: 10.1006/jtbi.2002.3078. Stent GS. 1963. Molecular Biology of Bacterial Viruses. San Francisco, Calif: W H

Viruses of haloarchaea.

PubMed

Luk, Alison W S; Williams, Timothy J; Erdmann, Susanne; Papke, R Thane; Cavicchioli, Ricardo

2014-11-13

In hypersaline environments, haloarchaea (halophilic members of the Archaea) are the dominant organisms, and the viruses that infect them, haloarchaeoviruses are at least ten times more abundant. Since their discovery in 1974, described haloarchaeoviruses include head-tailed, pleomorphic, spherical and spindle-shaped morphologies, representing Myoviridae, Siphoviridae, Podoviridae, Pleolipoviridae, Sphaerolipoviridae and Fuselloviridae families. This review overviews current knowledge of haloarchaeoviruses, providing information about classification, morphotypes, macromolecules, life cycles, genetic manipulation and gene regulation, and host-virus responses. In so doing, the review incorporates knowledge from laboratory studies of isolated viruses, field-based studies of environmental samples, and both genomic and metagenomic analyses of haloarchaeoviruses. What emerges is that some haloarchaeoviruses possess unique morphological and life cycle properties, while others share features with other viruses (e.g., bacteriophages). Their interactions with hosts influence community structure and evolution of populations that exist in hypersaline environments as diverse as seawater evaporation ponds, to hot desert or Antarctic lakes. The discoveries of their wide-ranging and important roles in the ecology and evolution of hypersaline communities serves as a strong motivator for future investigations of both laboratory-model and environmental systems.

Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus.

PubMed

Moncla, Louise H; Zhong, Gongxun; Nelson, Chase W; Dinis, Jorge M; Mutschler, James; Hughes, Austin L; Watanabe, Tokiko; Kawaoka, Yoshihiro; Friedrich, Thomas C

2016-02-10

Avian influenza virus reassortants resembling the 1918 human pandemic virus can become transmissible among mammals by acquiring mutations in hemagglutinin (HA) and polymerase. Using the ferret model, we trace the evolutionary pathway by which an avian-like virus evolves the capacity for mammalian replication and airborne transmission. During initial infection, within-host HA diversity increased drastically. Then, airborne transmission fixed two polymerase mutations that do not confer a detectable replication advantage. In later transmissions, selection fixed advantageous HA1 variants. Transmission initially involved a "loose" bottleneck, which became strongly selective after additional HA mutations emerged. The stringency and evolutionary forces governing between-host bottlenecks may therefore change throughout host adaptation. Mutations occurred in multiple combinations in transmitted viruses, suggesting that mammalian transmissibility can evolve through multiple genetic pathways despite phenotypic constraints. Our data provide a glimpse into avian influenza virus adaptation in mammals, with broad implications for surveillance on potentially zoonotic viruses. Copyright © 2016 Elsevier Inc. All rights reserved.

Viruses and viruslike particles of eukaryotic algae.

PubMed Central

Van Etten, J L; Lane, L C; Meints, R H

1991-01-01

Until recently there was little interest or information on viruses and viruslike particles of eukaryotic algae. However, this situation is changing. In the past decade many large double-stranded DNA-containing viruses that infect two culturable, unicellular, eukaryotic green algae have been discovered. These viruses can be produced in large quantities, assayed by plaque formation, and analyzed by standard bacteriophage techniques. The viruses are structurally similar to animal iridoviruses, their genomes are similar to but larger (greater than 300 kbp) than that of poxviruses, and their infection process resembles that of bacteriophages. Some of the viruses have DNAs with low levels of methylated bases, whereas others have DNAs with high concentrations of 5-methylcytosine and N6-methyladenine. Virus-encoded DNA methyltransferases are associated with the methylation and are accompanied by virus-encoded DNA site-specific (restriction) endonucleases. Some of these enzymes have sequence specificities identical to those of known bacterial enzymes, and others have previously unrecognized specificities. A separate rod-shaped RNA-containing algal virus has structural and nucleotide sequence affinities to higher plant viruses. Quite recently, viruses have been associated with rapid changes in marine algal populations. In the next decade we envision the discovery of new algal viruses, clarification of their role in various ecosystems, discovery of commercially useful genes in these viruses, and exploitation of algal virus genetic elements in plant and algal biotechnology. Images PMID:1779928

[Fluoride content of bottled natural mineral waters in Spain and prevention of dental caries].

PubMed

Maraver, Francisco; Vitoria, Isidro; Almerich-Silla, José Manuel; Armijo, Francisco

2015-01-01

The aim of the study was to determine the concentration of fluoride in natural mineral waters marketed in Spain in order to prevent tooth decay without the risk of causing dental fluorosis Descriptive and cross-sectional study during 2012. Natural mineral waters marketed in Spain. Three bottles with different bottling dates of 109 natural mineral waters (97 Spanish and 12 imported brands). Determination of fluoride by ion chromatography Median fluoride concentrations of the natural mineral waters bottled in Spain was 0.22 (range 0.00-4.16; interquartile range:0.37). Most samples (61 brands, 62%) contained less than 0.3mg/L. There are 19 Spanish brands with more than 0.6 mg/L. The median level in imported brands was 0.35 (range 0.10-1.21; interquartile range: 0.23). Only 28 of the 109 brands examined (25.6%) specified the fluoride content on the label. Good correlation was observed between the concentrations indicated and those determined. Fluoride concentrations in natural mineral waters showed high variation. Given the growing consumption of natural mineral waters in Spain, this type of information is important to make proper use of fluoride in the primary prevention of dental caries. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

Natural supramolecular building blocks: from virus coat proteins to viral nanoparticles.

PubMed

Liu, Zhi; Qiao, Jing; Niu, Zhongwei; Wang, Qian

2012-09-21

Viruses belong to a fascinating class of natural supramolecular structures, composed of multiple copies of coat proteins (CPs) that assemble into different shapes with a variety of sizes from tens to hundreds of nanometres. Because of their advantages including simple/economic production, well-defined structural features, unique shapes and sizes, genetic programmability and robust chemistries, recently viruses and virus-like nanoparticles (VLPs) have been used widely in biomedical applications and materials synthesis. In this critical review, we highlight recent advances in the use of virus coat proteins (VCPs) and viral nanoparticles (VNPs) as building blocks in self-assembly studies and materials development. We first discuss the self-assembly of VCPs into VLPs, which can efficiently incorporate a variety of different materials as cores inside the viral protein shells. Then, the self-assembly of VNPs at surfaces or interfaces is summarized. Finally, we discuss the co-assembly of VNPs with different functional materials (178 references).

Use of Bisphenol A-containing baby bottles in Cameroon and Nigeria and possible risk management and mitigation measures: community as milestone for prevention.

PubMed

Pouokam, Guy Bertrand; Ajaezi, Godwin Chukwuebuka; Mantovani, Alberto; Orisakwe, Orish Ebere; Frazzoli, Chiara

2014-05-15

The plasticizer Bisphenol A (BPA) is banned in baby bottles in many industrialized countries due to safety concerns. We provide a pilot view on the potential BPA exposure of bottle-fed children in sub-Saharan Africa through an enquiry on availability, accessibility and affordability of plastic baby bottles, usage pattern, and risk perception. An observational survey was conducted in a randomized group of vending sites (34 pharmacies; 87 shops and markets), in three cities (Yaoundé, Foumbot, Bafoussam) in Cameroon (two regions), and in two cities (Lagos, Port Harcourt) in Nigeria (two states). Interviews in vending sites and group discussions were conducted with 248 mothers. Cameroon and Nigeria showed a largely comparable situation. Plastic baby bottles are largely imported from industrialized countries, where a label indicates the presence/absence of BPA. In pharmacies most plastic baby bottles are labeled as BPA-free, whereas most bottles sold in shops are not BPA-free. BPA-containing bottles are more accessible and affordable, due to sale in common shops and lower costs. The meaning of the label BPA-free is unknown to both vendors and customers: the BPA issue is also largely unknown to policy makers and media and no regulation exists on food contact materials. The wide availability of BPA-containing baby bottles, lack of information and usage patterns (e.g. temperature and duration of heating) suggest a likely widespread exposure of African infants. Possible usage recommendations to mitigate exposure are indicated. Risk communication to policy makers, sellers and citizens is paramount to raise awareness and to oppose possible dumping from countries where BPA-containing materials are banned. Our pilot study points out relevant global health issues such as the capacity building of African communities on informed choices and usage of baby products, and the exploitation of international knowledge by African scientists and risk managers. Copyright © 2014 Elsevier B

Baby bottle steam sterilizers disinfect home nebulizers inoculated with bacterial respiratory pathogens.

PubMed

Towle, Dana; Callan, Deborah A; Farrel, Patricia A; Egan, Marie E; Murray, Thomas S

2013-09-01

Contaminated nebulizers are a potential source of bacterial infection but no single method is universally accepted for disinfection. We hypothesized that baby-bottle steam sterilizers effectively disinfect home nebulizers. Home nebulizers were inoculated with the common CF respiratory pathogens methicillin resistant Staphylococcus aureus, Burkholderia cepacia, Haemophilus influenzae, mucoid and non mucoid Pseudomonas aeruginosa, and Stenotrophomonas maltophilia. The nebulizers were swabbed for bacterial growth, treated with either the AVENT (Philips), the NUK Quick & Ready (Gerber) or DRY-POD (Camera Baby) baby bottle steam sterilizer and reswabbed for bacterial growth. All steam sterilizers were effective at disinfecting all home nebulizers. Viable bacteria were not recovered from any inoculated site after steam treatment, under any conditions tested. Steam treatment is an effective disinfection method. Additional studies are needed to confirm whether these results are applicable to the clinical setting. Copyright © 2012 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

A technique for individual atom delivery into a crossed vortex bottle beam trap using a dynamic 1D optical lattice.

PubMed

Dinardo, Brad A; Anderson, Dana Z

2016-12-01

We describe a system for loading a single atom from a reservoir into a blue-detuned crossed vortex bottle beam trap using a dynamic 1D optical lattice. The lattice beams are frequency chirped using acousto-optic modulators, which causes the lattice to move along its axial direction and behave like an optical conveyor belt. A stationary lattice is initially loaded with approximately 6000 atoms from a reservoir, and the conveyor belt transports them 1.1 mm from the reservoir to a bottle beam trap, where a single atom is loaded via light-assisted collisions. Photon counting data confirm that an atom can be delivered and loaded into the bottle beam trap 13.1% of the time.

Heavy Metals in Spring and Bottled Drinking Waters of Sibylline Mountains National Park (Central Italy).

PubMed

Annibaldi, Anna; Illuminati, Silvia; Truzzi, Cristina; Scarponi, Giuseppe

2018-02-01

Heavy metal concentrations (cadmium, lead, and copper) in spring, tap, and bottled waters of the Sibylline Mountains National Park (central Italy) were investigated using square wave anodic stripping voltammetry from 2004 to 2011. The mean (±SD) concentrations detected (1.3 ± 0.4 ng L -1 cadmium, 14 ± 6 ng L -1 lead, and 0.16 ± 0.10 μg L -1 copper) were below the limits stipulated by Italian and European legislation for drinking and natural mineral water. In the three studied areas of the park (Mount Bove north, Mount Bove south, and springs of River Nera) with very few exceptions, both mineral waters bottled in the area and aqueduct waters from public fountains had approximately the same metal concentrations as did the spring waters from which they were derived. Conversely, substantially higher metal concentrations were found at some sites in private houses, which may be due to release of metals from old metal pipes. At the time of this study, waters of Sibylline Mountains National Park were of good quality, and no influence of the bottling process on heavy metal concentrations was found.

Exploration of a variation of the bottle buoyancy technique for the assessment of body composition.

PubMed

Gulick, Dawn T; Geigle, Paula Richley

2003-05-01

Hydrostatic weighing has long been recognized as a reliable and valid method for the assessment of body composition. An alternative method known as bottle buoyancy (BB) was introduced by Katch, Hortobagyi, and Denahan in 1989. The purpose of this clinical investigation was to determine the accuracy of the BB technique using an 11-L container. Sixteen individuals (8 men, 8 women) were weighed hydrostatically using a chair/scale and the BB technique. The overall intraclass correlation coefficient for the two techniques was 0.9537. A 2-variable ANOVA was significant for gender but not for technique, and there was no interaction between variables. Thus, the BB technique appears to be an accurate substitute for the chair/scale technique for hydrostatic weighing. The BB method does not involve elaborate equipment and is portable. It could be improved with the use of multiple bottles of various volumes or a calibrated bottle to minimize the number of trials needed for accurate measurements. BB is a valuable, simple clinical tool for assessing body composition based on the principles of hydrostatic weighing and can be performed in any high school, college, or community swimming pool.

Monitoring Physiological Changes in Haloarchaeal Cell during Virus Release

PubMed Central

Svirskaitė, Julija; Oksanen, Hanna M.; Daugelavičius, Rimantas; Bamford, Dennis H.

2016-01-01

The slow rate of adsorption and non-synchronous release of some archaeal viruses have hindered more thorough analyses of the mechanisms of archaeal virus release. To address this deficit, we utilized four viruses that infect Haloarcula hispanica that represent the four virion morphotypes currently known for halophilic euryarchaeal viruses: (1) icosahedral internal membrane-containing SH1; (2) icosahedral tailed HHTV-1; (3) spindle-shaped His1; and (4) pleomorphic His2. To discern the events occurring as the progeny viruses exit, we monitored culture turbidity, as well as viable cell and progeny virus counts of infected and uninfected cultures. In addition to these traditional metrics, we measured three parameters associated with membrane integrity: the binding of the lipophilic anion phenyldicarbaundecaborane, oxygen consumption, and both intra- and extra-cellular ATP levels. PMID:26927156

Tap versus bottled water consumption: The influence of social norms, affect and image on consumer choice.

PubMed

Etale, Anita; Jobin, Marilou; Siegrist, Michael

2018-02-01

What drives consumers to choose bottled water instead of tap water where the latter is safe, accessible, costs far less, and in spite of its environmental impacts? This research investigates the influence of hitherto unexplored psychological drivers in an attempt to generate a more holistic understanding of the phenomenon, and strategies for designing more effective consumption reduction campaigns. Using data from an internet survey of Swiss and German respondents (N = 849) we investigated the role of, social norms, affect and image on water consumption. Results suggest that these psychological factors play a role in water consumption choice. Convenience was the only contextual predictor - the inconvenience of transporting bottled water has a negative effect on its consumption, and a positive effect on tap water consumption. Although concern about the effect of bottled water on the environment was not a significant predictor of tap water consumption, we found that for some people, a link exists between environmental concern and consumption choice. Ways through which consumers may be more effectively influenced towards environmentally-friendly consumption are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

Silicon oxide permeation barrier coating of PET bottles and foils

NASA Astrophysics Data System (ADS)

Steves, Simon; Deilmann, Michael; Awakowicz, Peter

2009-10-01

Modern packaging materials such as polyethylene terephthalate (PET) have displaced established materials in many areas of food and beverage packaging. Plastic packing materials offer are various advantages concerning production and handling. PET bottles for instance are non-breakable and lightweight compared to glass and metal containers. However, PET offers poor barrier properties against gas permeation. Therefore, the shelf live of packaged food is reduced. Permeation of gases can be reduced by depositing transparent plasma polymerized silicon oxide (SiOx) barrier coatings. A microwave (2.45 GHz) driven low pressure plasma reactor is developed based on a modified Plasmaline antenna to treat PET foils or bottles. To increase the barrier properties of the coatings furthermore a RF substrate bias (13.56 MHz) is applied. The composition of the coatings is analyzed by means of Fourier transform infrared (FTIR) spectroscopy regarding carbon and hydrogen content. Influence of gas phase composition and substrate bias on chemical composition of the coatings is discussed. A strong relation between barrier properties and film composition is found: good oxygen barriers are observed as carbon content is reduced and films become quartz-like. Regarding oxygen permeation a barrier improvement factor (BIF) of 70 is achieved.

Breast feeding, bottle feeding, and maternal autonomic responses to stress.

PubMed

Mezzacappa, Elizabeth Sibolboro; Kelsey, Robert M; Katkin, Edward S

2005-04-01

The aim of this study was to examine the effects of breast feeding on autonomic nervous system (ANS) response to stressors. Sympathetic and parasympathetic activities were examined before, during, and after standard laboratory stressors in women who were either exclusively breast feeding (n=14) or nonexclusively breast feeding (n=14), and in non-postpartum controls (n=15). Mothers who breast fed exclusively showed greater levels of parasympathetic cardiac modulation and slower heart rate (HR) throughout the session and less HR increase and preejection period (PEP) shortening to mental arithmetic (MA) than did nonexclusive breast feeders and controls. Nonexclusive breast-feeders showed greater electrodermal reactivity to, and greater differences in skin conductance response (SCR) frequency between baseline and recovery from cold pressor (CP) than did either exclusive breast-feeders or controls. Sympathetic activity was negatively related to the number of breast feedings and positively related to bottle feedings. Breast feeding shifts maternal ANS balance toward relatively greater parasympathetic and lesser sympathetic activity; the opposite occurs with bottle feeding. The frequency of feeding also is a critical factor in determining breast feeding effects on maternal ANS function.

Bacilliform DNA-containing plant viruses in the tropics: commonalities within a genetically diverse group.

PubMed

Borah, Basanta K; Sharma, Shweta; Kant, Ravi; Johnson, A M Anthony; Saigopal, Divi Venkata Ramana; Dasgupta, Indranil

2013-10-01

Plant viruses, possessing a bacilliform shape and containing double-stranded DNA, are emerging as important pathogens in a number of agricultural and horticultural crops in the tropics. They have been reported from a large number of countries in African and Asian continents, as well as from islands from the Pacific region. The viruses, belonging to two genera, Badnavirus and Tungrovirus, within the family Caulimoviridae, have genomes displaying a common plan, yet are highly variable, sometimes even between isolates of the same virus. In this article, we summarize the current knowledge with a view to revealing the common features embedded within the genetic diversity of this group of viruses. Virus; order Unassigned; family Caulimoviridae; genera Badnavirus and Tungrovirus; species Banana streak viruses, Bougainvillea spectabilis chlorotic vein banding virus, Cacao swollen shoot virus, Citrus yellow mosaic badnavirus, Dioscorea bacilliform viruses, Rice tungro bacilliform virus, Sugarcane bacilliform viruses and Taro bacilliform virus. Bacilliform in shape; length, 60-900 nm; width, 35-50 nm; circular double-stranded DNA of approximately 7.5 kbp with one or more single-stranded discontinuities. Each virus generally limited to its own host, including banana, bougainvillea, black pepper, cacao, citrus species, Dioscorea alata, rice, sugarcane and taro. Foliar streaking in banana and sugarcane, swelling of shoots in cacao, yellow mosaic in leaves and stems in citrus, brown spot in the tubers in yam and yellow-orange discoloration and stunting in rice. http://www.dpvweb.net. 2013 BSPP and JOHN WILEY & SONS LTD

COST EVALUATION OF AUTOMATED AND MANUAL POST- CONSUMER PLASTIC BOTTLE SORTING SYSTEMS

EPA Science Inventory

This project evaluates, on the basis of performance and cost, two Automated BottleSort® sorting systems for post-consumer commingled plastic containers developed by Magnetic Separation Systems. This study compares the costs to sort mixed bales of post-consumer plastic at these t...

Do infants fed directly from the breast have improved appetite regulation and slower growth during early childhood compared with infants fed from a bottle?

PubMed Central

2011-01-01

Background Behavioral mechanisms that contribute to the association between breastfeeding and reduced obesity risk are poorly understood. The purpose of this study was to evaluate the hypothesis that feeding human milk from the breast (direct breastfeeding) has a more optimal association with subsequent child appetite regulation behaviors and growth, when compared to bottle-feeding. Methods Children (n = 109) aged 3- to 6- years were retrospectively classified as directly breastfed (fed exclusively at the breast), bottle-fed human milk, or bottle-fed formula in the first three months of life. Young children's appetite regulation was examined by measuring three constructs (satiety response, food responsiveness, enjoyment of food) associated with obesity risk, using the Child Eating Behavior Questionnaire. Multinomial logistic regression analyses were used to test whether children bottle-fed either human milk or formula had reduced odds of high satiety and increased odds of high food responsiveness and high enjoyment of food compared to children fed directly from the breast. Current child weight status and growth trends from 6-36 months were also examined for their relation to direct breastfeeding and appetite regulation behaviors in early childhood. Results Children fed human milk in a bottle were 67% less likely to have high satiety responsiveness compared to directly breastfed children, after controlling for child age, child weight status, maternal race/ethnicity, and maternal education. There was no association of bottle-feeding (either human milk or formula) with young children's food responsiveness and enjoyment of food. There was neither an association of direct breastfeeding with current child weight status, nor was there a clear difference between directly breastfed and bottle-fed children in growth trajectories from 6- to 36-months. More rapid infant changes in weight-for-age score were associated with lower satiety responsiveness, higher food

Characteristics Associated With Adding Cereal Into the Bottle Among Immigrant Mother-Infant Dyads of Low Socioeconomic Status and Hispanic Ethnicity.

PubMed

Lucas, Candice Taylor; Messito, Mary Jo; Gross, Rachel S; Tomopoulos, Suzy; Fierman, Arthur H; Cates, Carolyn Brockmeyer; Johnson, Samantha Berkule; Dreyer, Benard; Mendelsohn, Alan L

2017-01-01

Determine maternal and infant characteristics associated with adding cereal into the bottle. Secondary data analysis. Study participants were immigrant, low-income, urban mother-infant dyads (n = 216; 91% Hispanic, 19% US-born) enrolled in a randomized controlled trial entitled the Bellevue Project for Early Language, Literacy and Education Success. Maternal characteristics (age, marital status, ethnicity, primary language, country of origin, education, work status, income, depressive symptoms, and concern about infant's future weight) and infant characteristics (gender, first born, and difficult temperament). Fisher exact test, chi-square test, and simultaneous multiple logistic regression of significant (P < .05) variables identified in unadjusted analyses. Twenty-seven percent of mothers added cereal into the bottle. After adjusting for confounding variables identified in bivariate analyses, mothers who were single (P = .02), had moderate to severe depressive symptoms (P = .01) and perceived their infant had a difficult temperament (P = .03) were more likely to add cereal into the bottle. Conversely, mothers who expressed concern about their infants becoming overweight were less likely to add cereal (P = .02). Health care providers should screen for adding cereal in infant bottles. Further research is needed to investigate the impact of adding cereal into the bottle on weight trajectories over time. Causal associations also need to be identified to effectively prevent this practice. Copyright © 2016 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

Fluorescence In Situ Hybridization with Peptide Nucleic Acid Probes for Rapid Identification of Candida albicans Directly from Blood Culture Bottles

PubMed Central

Rigby, Susan; Procop, Gary W.; Haase, Gerhard; Wilson, Deborah; Hall, Geraldine; Kurtzman, Cletus; Oliveira, Kenneth; Von Oy, Sabina; Hyldig-Nielsen, Jens J.; Coull, James; Stender, Henrik

2002-01-01

A new fluorescence in situ hybridization (FISH) method that uses peptide nucleic acid (PNA) probes for identification of Candida albicans directly from positive-blood-culture bottles in which yeast was observed by Gram staining (herein referred to as yeast-positive blood culture bottles) is described. The test (the C. albicans PNA FISH method) is based on a fluorescein-labeled PNA probe that targets C. albicans 26S rRNA. The PNA probe is added to smears made directly from the contents of the blood culture bottle and hybridized for 90 min at 55°C. Unhybridized PNA probe is removed by washing of the mixture (30 min), and the smears are examined by fluorescence microscopy. The specificity of the method was confirmed with 23 reference strains representing phylogenetically related yeast species and 148 clinical isolates covering the clinically most significant yeast species, including C. albicans (n = 72), C. dubliniensis (n = 58), C. glabrata (n = 5), C. krusei (n = 2), C. parapsilosis (n = 4), and C. tropicalis (n = 3). The performance of the C. albicans PNA FISH method as a diagnostic test was evaluated with 33 routine and 25 simulated yeast-positive blood culture bottles and showed 100% sensitivity and 100% specificity. It is concluded that this 2.5-h method for the definitive identification of C. albicans directly from yeast-positive blood culture bottles provides important information for optimal antifungal therapy and patient management. PMID:12037084

Breast and Bottle Feeding as Risk Factors for Dental Caries: A Systematic Review and Meta-Analysis

PubMed Central

Avila, Walesca M.; Pordeus, Isabela A.; Paiva, Saul M.; Martins, Carolina C.