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Sample records for acoustic startle test

  1. Induction of enhanced acoustic startle response by noise exposure: dependence on exposure conditions and testing parameters and possible relevance to hyperacusis.

    PubMed

    Salloum, Rony H; Yurosko, Christopher; Santiago, Lia; Sandridge, Sharon A; Kaltenbach, James A

    2014-01-01

    There has been a recent surge of interest in the development of animal models of hyperacusis, a condition in which tolerance to sounds of moderate and high intensities is diminished. The reasons for this decreased tolerance are likely multifactorial, but some major factors that contribute to hyperacusis are increased loudness perception and heightened sensitivity and/or responsiveness to sound. Increased sound sensitivity is a symptom that sometimes develops in human subjects after acoustic insult and has recently been demonstrated in animals as evidenced by enhancement of the acoustic startle reflex following acoustic over-exposure. However, different laboratories have obtained conflicting results in this regard, with some studies reporting enhanced startle, others reporting weakened startle, and still others reporting little, if any, change in the amplitude of the acoustic startle reflex following noise exposure. In an effort to gain insight into these discrepancies, we conducted measures of acoustic startle responses (ASR) in animals exposed to different levels of sound, and repeated such measures on consecutive days using a range of different startle stimuli. Since many studies combine measures of acoustic startle with measures of gap detection, we also tested ASR in two different acoustic contexts, one in which the startle amplitudes were tested in isolation, the other in which startle amplitudes were measured in the context of the gap detection test. The results reveal that the emergence of chronic hyperacusis-like enhancements of startle following noise exposure is highly reproducible but is dependent on the post-exposure thresholds, the time when the measures are performed and the context in which the ASR measures are obtained. These findings could explain many of the discrepancies that exist across studies and suggest guidelines for inducing in animals enhancements of the startle reflex that may be related to hyperacusis.

  2. Habituation and prepulse inhibition of acoustic startle in rodents.

    PubMed

    Valsamis, Bridget; Schmid, Susanne

    2011-09-01

    The acoustic startle response is a protective response, elicited by a sudden and intense acoustic stimulus. Facial and skeletal muscles are activated within a few milliseconds, leading to a whole body flinch in rodents(1). Although startle responses are reflexive responses that can be reliably elicited, they are not stereotypic. They can be modulated by emotions such as fear (fear potentiated startle) and joy (joy attenuated startle), by non-associative learning processes such as habituation and sensitization, and by other sensory stimuli through sensory gating processes (prepulse inhibition), turning startle responses into an excellent tool for assessing emotions, learning, and sensory gating, for review see( 2, 3). The primary pathway mediating startle responses is very short and well described, qualifying startle also as an excellent model for studying the underlying mechanisms for behavioural plasticity on a cellular/molecular level(3). We here describe a method for assessing short-term habituation, long-term habituation and prepulse inhibition of acoustic startle responses in rodents. Habituation describes the decrease of the startle response magnitude upon repeated presentation of the same stimulus. Habituation within a testing session is called short-term habituation (STH) and is reversible upon a period of several minutes without stimulation. Habituation between testing sessions is called long-term habituation (LTH)(4). Habituation is stimulus specific(5). Prepulse inhibition is the attenuation of a startle response by a preceding non-startling sensory stimulus(6). The interval between prepulse and startle stimulus can vary from 6 to up to 2000 ms. The prepulse can be any modality, however, acoustic prepulses are the most commonly used. Habituation is a form of non-associative learning. It can also be viewed as a form of sensory filtering, since it reduces the organisms' response to a non-threatening stimulus. Prepulse inhibition (PPI) was originally

  3. Prefrontal oxygenation and the acoustic startle eyeblink response during exercise: A test of the dual-mode model.

    PubMed

    Tempest, Gavin D; Parfitt, Gaynor

    2017-03-30

    The interplay between the prefrontal cortex and amygdala is proposed to explain the regulation of affective responses (pleasure/displeasure) during exercise as outlined in the dual-mode model. However, due to methodological limitations the dual-mode model has not been fully tested. In this study, prefrontal oxygenation (using near-infrared spectroscopy) and amygdala activity (reflected by eyeblink amplitude using acoustic startle methodology) were recorded during exercise standardized to metabolic processes: 80% of ventilatory threshold (below VT), at the VT, and at the respiratory compensation point (RCP). Self-reported tolerance of the intensity of exercise was assessed prior to, and affective responses recorded during exercise. The results revealed that, as the intensity of exercise became more challenging (from below VT to RCP), prefrontal oxygenation was larger and eyeblink amplitude and affective responses were reduced. Below VT and at VT, larger prefrontal oxygenation was associated with larger eyeblink amplitude. At the RCP, prefrontal oxygenation was greater in the left than right hemisphere, and eyeblink amplitude explained significant variance in affective responses (with prefrontal oxygenation) and self-reported tolerance. These findings highlight the role of the prefrontal cortex and potentially the amygdala in the regulation of affective (particularly negative) responses during exercise at physiologically challenging intensities (above VT). In addition, a psychophysiological basis of self-reported tolerance is indicated. This study provides some support of the dual-mode model and insight into the neural basis of affective responses during exercise.

  4. Hyperreactivity to weak acoustic stimuli and prolonged acoustic startle latency in children with autism spectrum disorders

    PubMed Central

    2014-01-01

    Background People with autism spectrum disorders (ASD) are known to have enhanced auditory perception, however, acoustic startle response to weak stimuli has not been well documented in this population. The objectives of this study are to evaluate the basic profile of acoustic startle response, including peak startle latency and startle magnitude to weaker stimuli, in children with ASD and typical development (TD), and to evaluate their relationship to ASD characteristics. Methods We investigated acoustic startle response with weak and strong acoustic stimuli in 12 children with ASD and 28 children with TD, analyzing the relationship between startle measures and quantitative autistic traits assessed with the Social Responsiveness Scale (SRS). The electromyographic activity of the left orbicularis oculi muscle to acoustic stimuli of 65 to 115 dB sound pressure level (SPL), in increments of 5 dB, was measured to evaluate acoustic startle response. The average eyeblink magnitude for each acoustic stimuli intensity and the average peak startle latency of acoustic startle response were evaluated. Results The magnitude of the acoustic startle response to weak stimuli (85 dB or smaller) was greater in children with ASD. The peak startle latency was also prolonged in individuals with ASD. The average magnitude of the acoustic startle response for stimulus intensities greater than 85 dB was not significantly larger in the ASD group compared with the controls. Both greater startle magnitude in response to weak stimuli (particularly at 85 dB) and prolonged peak startle latency were significantly associated with total scores, as well as several subscales of the SRS in the whole sample. We also found a significant relationship between scores on the social cognition subscale of the SRS and the average magnitude of the acoustic startle response for stimulus intensities of 80 and 85 dB in the TD group. Conclusions Children with ASD exhibited larger startle magnitude to weak

  5. Winter is coming: Seasonality and the acoustic startle reflex.

    PubMed

    Armbruster, Diana; Brocke, Burkhard; Strobel, Alexander

    2017-02-01

    Circannual rhythms and seasonality have long been in the interest of research. In humans, seasonal changes in mood have been extensively investigated since a substantial part of the population experiences worsening of mood during winter. Questions remain regarding accompanying physiological phenomena. We report seasonal effects on the acoustic startle response in a cross-sectional (n=124) and a longitudinal sample (n=23). Startle magnitudes were larger in winter (sample 1: p=0.026; sample 2: p=0.010) compared to summer months. Although the findings need to be replicated they may have implications regarding the timing of startle experiments.

  6. Amygdala central nucleus lesions attenuate acoustic startle stimulus-evoked heart rate changes in rats.

    PubMed

    Young, B J; Leaton, R N

    1996-04-01

    Amygdala central nucleus (CNA) lesions were used to test the hypothesis that stimulus-evoked heart rate changes can reflect the development of fear during acoustic startle testing. A 120-dB white noise startle stimulus produced freezing as well as phasic heart rate accelerations and decelerations, and an abrupt decrease in tonic heart rate, in sham-operated rats. These responses were all significantly reduced in CNA-lesioned rats. In contrast, an 87-dB stimulus elicited only significant phasic decelerations that were similarly attenuated by the CNA lesions. In a follow-up experiment, the CNA lesions also attenuated phasic cardiac decelerations evoked by a conditioned stimulus-like, 85-dB pure tone. The results support the contention (B. J. Young & R.N. Leaton, 1994) that heart rate changes can reflect fear conditioned during acoustic startle testing and, in addition, suggest that the amygdala mediates responses to nonsignal acoustic stimuli.

  7. The Influence of Stuttering Severity on Acoustic Startle Responses

    ERIC Educational Resources Information Center

    Ellis, John B.; Finan, Donald S.; Ramig, Peter R.

    2008-01-01

    Purpose: This study examined the potential impact of stuttering severity, as measured by the Perceptions of Stuttering Inventory (Woolf, 1967) on acoustic startle responses. Method: Three groups, consisting of 10 nonstuttering adults, 9 mild stutterering adults, and 11 moderate/severe stutterering adults, were presented with identical 95-dB…

  8. Stuttering and Sensory Gating: A Study of Acoustic Startle Prepulse Inhibition

    ERIC Educational Resources Information Center

    Alm, Per A.

    2006-01-01

    It was hypothesized that stuttering may be related to impaired sensory gating, leading to overflow of superfluous disturbing auditory feedback and breakdown of the speech sequence. This hypothesis was tested using the "acoustic startle prepulse inhibition" (PPI) paradigm. A group of 22 adults with developmental stuttering were compared…

  9. An acoustic startle-based method of assessing frequency discrimination in mice.

    PubMed

    Clause, Amanda; Nguyen, Tuan; Kandler, Karl

    2011-08-30

    The acoustic startle response (ASR) is a reflexive contraction of skeletal muscles in response to a loud, abrupt acoustic stimulus. ASR magnitude is reduced if the startle stimulus is preceded by a weaker acoustic or non-acoustic stimulus, a phenomenon known as prepulse inhibition (PPI). PPI has been used to test various aspects of sensory discrimination in both animals and humans. Here we show that PPI of the ASR is an advantageous method of assessing frequency discrimination. We describe the apparatus and its performance testing frequency discrimination in young CD1 mice. Compared to classical conditioning paradigms, PPI of the ASR is less time consuming, produces robust results, and can be used without training even in young animals. This approach can be used to investigate the neuronal mechanisms underlying frequency discrimination, its maturation during development, and its relationship to tonotopic organization.

  10. First trial postural reactions to unexpected balance disturbances: a comparison with the acoustic startle reaction.

    PubMed

    Oude Nijhuis, Lars B; Allum, John H J; Valls-Solé, Josep; Overeem, Sebastiaan; Bloem, Bastiaan R

    2010-11-01

    Unexpected support-surface movements delivered during stance elicit "first trial" postural reactions, which are larger and cause greater instability compared with habituated responses. The nature of this first trial reaction remains unknown. We hypothesized that first trial postural reactions consist of a generalized startle reaction, with a similar muscle synergy as the acoustic startle response, combined with an automatic postural reaction. Therefore we compared acoustic startle responses to first trial postural reactions. Eight healthy subjects stood on a support surface that unexpectedly rotated backwards 10 times, followed by 10 startling acoustic stimuli, or vice versa. Outcome measures included full body kinematics and surface EMG from muscles involved in startle reactions or postural control. Postural perturbations and startling acoustic stimuli both elicited a clear first trial reaction, as reflected by larger kinematic and EMG responses. The ensuing habituation rate to repeated identical stimuli was comparable for neck and trunk muscles in both conditions. Onset latencies in neck muscles occurred significantly later for first trial perturbations compared with startle responses, but earlier in trunk muscles. Our results show that platform tilting initially induces reactions larger than needed to maintain equilibrium. For neck and trunk muscles, these first trial postural reactions resembled acoustic startle reflexes. First trial postural reactions may be triggered by interaction of afferent volleys formed by somatosensory and vestibular inputs. Acoustic startle reactions may also be partially triggered by vestibular inputs. Similar muscle activation driven by vestibular inputs may be the common element of first trial postural responses and acoustic startle reactions.

  11. A Hardware-and-Software System for Experimental Studies of the Acoustic Startle Response in Laboratory Rodents.

    PubMed

    Pevtsov, E F; Storozheva, Z I; Proshin, A T; Pevtsova, E I

    2016-02-01

    We developed and tested a novel hardware-and-software system for recording the amplitude of the acoustic startle response in rodents. In our experiments, the baseline indexes of acoustic startle response in laboratory rats and pre-stimulation inhibition under the standard delivery of acoustic stimulation were similar to those evaluated by other investigators on foreign devices. The proposed system is relatively cheap and provides the possibility of performing experiments on freely moving specimens. It should be emphasized that the results of studies can be processed with free-access software.

  12. Enhanced acoustic startle responding in rats with radiation-induced hippocampal granule cell hypoplasia

    SciTech Connect

    Mickley, G.A.; Ferguson, J.L.

    1989-01-01

    Irradiation of the neonatal rat hippocampus reduces the proliferation of granule cells in the dentate gyrus and results in locomotor hyperactivity, behavioral preservation, and deficits on some learned tasks. In order to address the role of changes in stimulus salience and behavioral inhibition in animals with this type of brain damage, irradiated and normal rats were compared in their startle reactions to an acoustic stimulus. Irradiated rats startled with a consistently higher amplitude than control and were more likely to exhibit startle responses. These animals with hippocampal damage also failed to habituate to the startle stimulus and, under certain circumstances, showed potentiated startle responses after many tone presentations.

  13. Excitatory and Inhibitory Effects of Serotonin on Sensorimotor Reactivity Measured with Acoustic Startle

    NASA Astrophysics Data System (ADS)

    Davis, Michael; Astrachan, David I.; Kass, Elizabeth

    1980-07-01

    Serotonin infused into the lateral ventricle in rats produced a dose-dependent depression of the acoustic startle reflex. When infused onto the spinal cord, serotonin produced a dose-dependent increase in startle. Thus the same neurotransmitter can modulate the same behavior in opposite ways, depending on which part of the central nervous system is involved.

  14. Stuttering and sensory gating: a study of acoustic startle prepulse inhibition.

    PubMed

    Alm, Per A

    2006-06-01

    It was hypothesized that stuttering may be related to impaired sensory gating, leading to overflow of superfluous disturbing auditory feedback and breakdown of the speech sequence. This hypothesis was tested using the acoustic startle prepulse inhibition (PPI) paradigm. A group of 22 adults with developmental stuttering were compared with controls regarding the degree of PPI. No significant differences were found between the stuttering adults and the control group; the groups showed similar means and distribution. Likewise, no relation between the degree of PPI and the effect of altered auditory feedback on stuttering was found. In summary, the results of the study indicate that there is no relation between stuttering and PPI.

  15. Habituation of parasympathetic-mediated heart rate responses to recurring acoustic startle

    PubMed Central

    Chen, Kuan-Hua; Aksan, Nazan; Anderson, Steven W.; Grafft, Amanda; Chapleau, Mark W.

    2014-01-01

    Startle habituation is a type of implicit and automatic emotion regulation. Diminished startle habituation is linked to several psychiatric or neurological disorders. Most previous studies quantified startle habituation by assessing skin conductance response (SCR; reflecting sympathetic-mediated sweating), eye-blink reflex, or motor response. The habituation of parasympathetic-mediated heart rate responses to recurrent startle stimuli is not well understood. A variety of methods and metrics have been used to quantify parasympathetic activity and its effects on the heart. We hypothesized that these different measures reflect unique psychological and physiological processes that may habituate differently during repeated startle stimuli. We measured cardiac inter-beat intervals (IBIs) to recurring acoustic startle probes in 75 eight year old children. Eight acoustic stimuli of 500 ms duration were introduced at intervals of 15–25 s. Indices of parasympathetic effect included: (1) the initial rapid decrease in IBI post-startle mediated by parasympathetic inhibition (PI); (2) the subsequent IBI recovery mediated by parasympathetic reactivation (PR); (3) rapid, beat-to-beat heart rate variability (HRV) measured from the first seven IBIs following each startle probe. SCR and motor responses to startle were also measured. Results showed that habituation of PR (IBI recovery and overshoot) and SCRs were rapid and robust. In addition, changes in PR and SCR were significantly correlated. In contrast, habituation of PI (the initial decrease in IBI) was slower and relatively modest. Measurement of rapid HRV provided an index reflecting the combination of PI and PR. We conclude that different measures of parasympathetic-mediated heart rate responses to repeated startle probes habituate in a differential manner. PMID:25477830

  16. Baseline and Modulated Acoustic Startle Responses in Adolescent Girls with Posttraumatic Stress Disorder

    ERIC Educational Resources Information Center

    Lipschitz, Deborah S.; Mayes, Linda M.; Rasmusson, Ann M.; Anyan, Walter; Billingslea, Eileen; Gueorguieva, Ralitza; Southwick, Steven M.

    2005-01-01

    Objective: To assess baseline and modulated acoustic startle responses in adolescent girls with posttraumatic stress disorder (PTSD). Method: Twenty-eight adolescent girls with PTSD and 23 healthy control girls were recruited for participation in the study. Acoustic stimuli were bursts of white noise of 104 dB presented biaurally through…

  17. Acoustic startle response in rats predicts inter-individual variation in fear extinction.

    PubMed

    Russo, Amanda S; Parsons, Ryan G

    2017-03-01

    Although a large portion of the population is exposed to a traumatic event at some point, only a small percentage of the population develops post-traumatic stress disorder (PTSD), suggesting the presence of predisposing factors. Abnormal acoustic startle response (ASR) has been shown to be associated with PTSD, implicating it as a potential predictor of the development of PTSD-like behavior. Since poor extinction and retention of extinction learning are characteristic of PTSD patients, it is of interest to determine if abnormal ASR is predictive of development of such deficits. To determine whether baseline ASR has utility in predicting the development of PTSD-like behavior, the relationship between baseline ASR and freezing behavior following Pavlovian fear conditioning was examined in a group of adult, male Sprague-Dawley rats. Baseline acoustic startle response (ASR) was assessed preceding exposure to a Pavlovian fear conditioning paradigm where freezing behavior was measured during fear conditioning, extinction training, and extinction testing. Although there was no relationship between baseline ASR and fear memory following conditioning, rats with low baseline ASR had significantly lower magnitude of retention of the extinction memory than rats with high baseline ASR. The results suggest that baseline ASR has value as a predictive index of the development of a PTSD-like phenotype.

  18. Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: A genome-wide association study

    PubMed Central

    VAIDYANATHAN, UMA; MALONE, STEPHEN M.; MILLER, MICHAEL B.; McGUE, MATT; IACONO, WILLIAM G.

    2014-01-01

    Acoustic startle responses have been studied extensively in relation to individual differences and psychopathology. We examined three indices of the blink response in a picture-viewing paradigm—overall startle magnitude across all picture types, and aversive and pleasant modulation scores—in 3,323 twins and parents. Biometric models and molecular genetic analyses showed that half the variance in overall startle was due to additive genetic effects. No single nucleotide polymorphism was genome-wide significant, but GRIK3 did produce a significant effect when examined as part of a candidate gene set. In contrast, emotion modulation scores showed little evidence of heritability in either biometric or molecular genetic analyses. However, in a genome-wide scan, PARP14 did produce a significant effect for aversive modulation. We conclude that, although overall startle retains potential as an endophenotype, emotion-modulated startle does not. PMID:25387708

  19. Acoustic startle responses and temperament in individuals who stutter.

    PubMed

    Guitar, Barry

    2003-02-01

    Fourteen individuals who stutter and 14 individuals who do not stutter were presented with 10 bursts of white noise to assess the magnitude of their eyeblink responses as a measure of temperament. Both the magnitude of the eyeblink response to the initial noise burst and the mean of the 10 responses were significantly greater for the stuttering group. The Taylor-Johnson Temperament Analysis (R. M. Taylor & L P. Morrison, 1996) did not distinguish between the two groups, but informal follow-up statistics indicated that the Nervous subscale showed a significant group difference. Scores on this subscale were also significantly positively correlated with the magnitude of the startle response. A discriminant analysis demonstrated that although both the startle response and the nervous trait differentiated the two groups, the startle response measures were more powerful in making this differentiation.

  20. Anger and aggression problems in veterans are associated with an increased acoustic startle reflex.

    PubMed

    Heesink, Lieke; Kleber, Rolf; Häfner, Michael; van Bedaf, Laury; Eekhout, Iris; Geuze, Elbert

    2017-02-01

    Anger and aggression are frequent problems in deployed military personnel. A lowered threshold of perceiving and responding to threat can trigger impulsive aggression. This can be indicated by an exaggerated startle response. Fifty-two veterans with anger and aggression problems (Anger group) and 50 control veterans were tested using a startle experiment with 10 startle probes and 10 prepulse trials, presented in a random order and with a random interval between the trials. Predictors (demographics, Trait Anger, State Anger, Harm Avoidance and Anxious Arousal) for the startle response within the Anger group were tested. Increased EMG responses were found to the startle probes in the Anger Group compared to the Control group, but not to the prepulse trials. Furthermore, Harm Avoidance and State Anger predicted the increased startle reflex within the Anger group, whereas Trait Anger was negatively related to the startle reflex. These findings indicate that threat reactivity is increased in anger and aggression problems. These problems are not only caused by an anxious predisposition, the degree of anger also predicts the startle reflex.

  1. On Again, Off Again Effects of Gonadectomy on the Acoustic Startle Reflex in Adult Male Rats

    PubMed Central

    Turvin, J.C.; Messer, W.S.

    2007-01-01

    Numerous studies have shown sex and/or estrous cycle differences in the acoustic startle reflex (ASR) and its prepulse inhibition (PPI) in humans and animals. However, few have examined the effects of hormone manipulations on these behaviors. This study paired gonadectomy (GDX) in adult male rats with testing for ASR and PPI at 2, 4, 9, 16, 23, 30 and 37 days after surgery. Initial studies of control, GDX and GDX rats given testosterone propionate revealed no group differences in PPI, but did reveal phasic facilitation of the ASR in GDX rats that was greatest on the first and final testing sessions and that was attenuated by testosterone. A second study addressing roles for estrogen and androgen signaling tested new control and GDX rats along with GDX rats given estradiol or the non-aromatizable androgen, 5-alpha-dihydrotestosterone and revealed no group differences in PPI, and increases in ASR in GDX rats that were largest during the first and final testing sessions and that were attenuated by both hormone replacements. However, while responses in GDX rats given testosterone were similar to those of controls, ASR in estradiol- and to a lesser extent in dihydrotestosterone-treated GDX rats were typically lower than in controls. This may suggest that hormone modulation of the ASR requires synergistic estrogen and androgen actions. In the male brain where this can be achieved by local steroid metabolism, the enzymes responsible, e.g., aromatase, could help identify loci in the startle circuitry that may be especially relevant for the hormone modulation observed. PMID:17169383

  2. Dissociative identity disorder and prepulse inhibition of the acoustic startle reflex.

    PubMed

    Dale, Karl Yngvar; Flaten, Magne Arve; Elden, Ake; Holte, Arne

    2008-06-01

    A group of persons with dissociative identity disorder (DID) was compared with a group of persons with other dissociative disorders, and a group of nondiagnosed controls with regard to prepulse inhibition (PPI) of the acoustic startle reflex. The findings suggest maladaptive attentional processes at a controlled level, but not at a preattentive automatic level, in persons with DID. The prepulse occupied more controlled attentional resources in the DID group compared with the other two groups. Preattentive automatic processing, on the other hand, was normal in the DID group. Moreover, startle reflexes did not habituate in the DID group. In conclusion, increased PPI and delayed habituation is consistent with increased vigilance in individuals with DID. The present findings of reduced habituation of startle reflexes and increased PPI in persons with DID suggest the operation of a voluntary process that directs attention away from unpleasant or threatening stimuli. Aberrant voluntary attentional processes may thus be a defining characteristic in DID.

  3. Dissociative identity disorder and prepulse inhibition of the acoustic startle reflex

    PubMed Central

    Dale, Karl Yngvar; Flaten, Magne Arve; Elden, Åke; Holte, Arne

    2008-01-01

    A group of persons with dissociative identity disorder (DID) was compared with a group of persons with other dissociative disorders, and a group of nondiagnosed controls with regard to prepulse inhibition (PPI) of the acoustic startle reflex. The findings suggest maladaptive attentional processes at a controlled level, but not at a preattentive automatic level, in persons with DID. The prepulse occupied more controlled attentional resources in the DID group compared with the other two groups. Preattentive automatic processing, on the other hand, was normal in the DID group. Moreover, startle reflexes did not habituate in the DID group. In conclusion, increased PPI and delayed habituation is consistent with increased vigilance in individuals with DID. The present findings of reduced habituation of startle reflexes and increased PPI in persons with DID suggest the operation of a voluntary process that directs attention away from unpleasant or threatening stimuli. Aberrant voluntary attentional processes may thus be a defining characteristic in DID. PMID:18830396

  4. Prepulse Inhibition of the Acoustic Startle Reflex in High Functioning Autism

    PubMed Central

    Gruendler, Theo O. J.; Vogeley, Kai; Klosterkötter, Joachim; Kuhn, Jens

    2014-01-01

    Background High functioning autism is an autism spectrum disorder that is characterized by deficits in social interaction and communication as well as repetitive and restrictive behavior while intelligence and general cognitive functioning are preserved. According to the weak central coherence account, individuals with autism tend to process information detail-focused at the expense of global form. This processing bias might be reflected by deficits in sensorimotor gating, a mechanism that prevents overstimulation during the transformation of sensory input into motor action. Prepulse inhibition is an operational measure of sensorimotor gating, which indicates an extensive attenuation of the startle reflex that occurs when a startling pulse is preceded by a weaker stimulus, the prepulse. Methods In the present study, prepulse inhibition of acoustic startle was compared between 17 adults with high functioning autism and 17 sex-, age-, and intelligence-matched controls by means of electromyography. Results Results indicate that participants with high functioning autism exhibited significantly higher startle amplitudes than the control group. However, groups did not differ with regard to PPI or habituation of startle. Discussion These findings challenge the results of two previous studies that reported prepulse inhibition deficits in high-functioning autism and suggest that sensorimotor gating is only impaired in certain subgroups with autism spectrum disorder. PMID:24643088

  5. Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer's disease.

    PubMed

    O'Leary, Timothy P; Shin, Sooyoun; Fertan, Emre; Dingle, Rachel N; Almuklass, Awad; Gunn, Rhian K; Yu, Zhiping; Wang, Jian; Brown, Richard E

    2017-01-29

    Hearing dysfunction has been associated with Alzheimer's disease in humans, but there is little data on the auditory function of mouse models of Alzheimer's disease. Furthermore, characterization of hearing ability in mouse models is needed to ensure that tests of cognition that use auditory stimuli are not confounded by hearing dysfunction. Therefore we assessed acoustic startle response and pre-pulse inhibition in the double transgenic 5xFAD mouse model of Alzheimer's disease from 3-4 to 16 months of age. The 5xFAD mice demonstrated an age-related decline in acoustic startle as early as 3-4 months of age. We subsequently tested Auditory Brainstem Response (ABR) thresholds at 4 and 13-14 months of age using tone-bursts at frequencies of 2- 32 kHz. The 5xFAD mice showed increased ABR thresholds for tone-bursts between 8 and 32Khz at 13-14 months of age. Finally, cochleae were extracted and basilar membranes were dissected to count hair cell loss across the cochlea. The 5xFAD mice showed significantly greater loss of both inner and outer hair cells at the apical and basal ends of the basilar membrane than wildtype mice at 15-16 months of age. These results indicate that the 5xFAD mouse model of Alzheimer's disease shows age-related decreases in acoustic startle responses, which are at least partially due to age-related peripheral hearing loss. Therefore, we caution against the use of cognitive tests that rely on audition in 5xFAD mice over 3-4 months of age, without first confirming that performance is not confounded by hearing dysfunction.

  6. Interaction between acoustic startle and habituated neck postural responses in seated subjects.

    PubMed

    Blouin, Jean-Sébastien; Siegmund, Gunter P; Timothy Inglis, J

    2007-04-01

    Postural and startle responses rapidly habituate with repeated exposures to the same stimulus, and the first exposure to a seated forward acceleration elicits a startle response in the neck muscles. Our goal was to examine how the acoustic startle response is integrated with the habituated neck postural response elicited by forward accelerations of seated subjects. In experiment 1, 14 subjects underwent 11 sequential forward accelerations followed by 5 additional sled accelerations combined with a startling tone (124-dB sound pressure level) initiated 18 ms after sled acceleration onset. During the acceleration-only trials, changes consistent with habituation occurred in the root-mean-square amplitude of the neck muscles and in the peak amplitude of five head and torso kinematic variables. The subsequent addition of the startling tone restored the amplitude of the neck muscles and four of the five kinematic variables but shortened onset of muscle activity by 9-12 ms. These shortened onset times were further explored in experiment 2, wherein 16 subjects underwent 11 acceleration-only trials followed by 15 combined acceleration-tone trials with interstimulus delays of 0, 13, 18, 23, and 28 ms. Onset times shortened further for the 0- and 13-ms delays but did not lengthen for the 23- and 28-ms delays. These temporal and spatial changes in EMG can be explained by a summation of the excitatory drive converging at or before the neck muscle motoneurons. The present observations suggest that habituation to repeated sled accelerations involves extinguishing the startle response and tuning the postural response to the whole body disturbance.

  7. A fast cholinergic modulation of the primary acoustic startle circuit in rats.

    PubMed

    Gómez-Nieto, Ricardo; Sinex, Donal G; Horta-Júnior, José de Anchieta C; Castellano, Orlando; Herrero-Turrión, Javier M; López, Dolores E

    2014-09-01

    Cochlear root neurons (CRNs) are the first brainstem neurons which initiate and participate in the full expression of the acoustic startle reflex. Although it has been suggested that a cholinergic pathway from the ventral nucleus of the trapezoid body (VNTB) conveys auditory prepulses to the CRNs, the neuronal origin of the VNTB-CRNs projection and the role it may play in the cochlear root nucleus remain uncertain. To determine the VNTB neuronal type which projects to CRNs, we performed tract-tracing experiments combined with mechanical lesions, and morphometric analyses. Our results indicate that a subpopulation of non-olivocochlear neurons projects directly and bilaterally to CRNs via the trapezoid body. We also performed a gene expression analysis of muscarinic and nicotinic receptors which indicates that CRNs contain a cholinergic receptor profile sufficient to mediate the modulation of CRN responses. Consequently, we investigated the effects of auditory prepulses on the neuronal activity of CRNs using extracellular recordings in vivo. Our results show that CRN responses are strongly inhibited by auditory prepulses. Unlike other neurons of the cochlear nucleus, the CRNs exhibited inhibition that depended on parameters of the auditory prepulse such as intensity and interstimulus interval, showing their strongest inhibition at short interstimulus intervals. In sum, our study supports the idea that CRNs are involved in the auditory prepulse inhibition of the acoustic startle reflex, and confirms the existence of multiple cholinergic pathways that modulate the primary acoustic startle circuit.

  8. Relationship between Toxoplasma gondii seropositivity and acoustic startle response in an inner-city population.

    PubMed

    Massa, Nick M; Duncan, Erica; Jovanovic, Tanja; Kerley, Kimberly; Weng, Lei; Gensler, Lauren; Lee, Samuel S; Norrholm, Seth; Powers, Abigail; Almli, Lynn M; Gillespie, Charles F; Ressler, Kerry; Pearce, Bradley D

    2017-03-01

    Toxoplasma gondii (TOXO) is a neuroinvasive protozoan parasite that induces the formation of persistent cysts in mammalian brains. It infects approximately 1.1million people in the United States annually. Latent TOXO infection is implicated in the etiology of psychiatric disorders, especially schizophrenia (SCZ), and has been correlated with modestly impaired cognition. The acoustic startle response (ASR) is a reflex seen in all mammals. It is mediated by a simple subcortical circuit, and provides an indicator of neural function. We previously reported the association of TOXO with slowed acoustic startle latency, an index of neural processing speed, in a sample of schizophrenia and healthy control subjects. The alterations in neurobiology with TOXO latent infection may not be specific to schizophrenia. Therefore we examined TOXO in relation to acoustic startle in an urban, predominately African American, population with mixed psychiatric diagnoses, and healthy controls. Physiological and diagnostic data along with blood samples were collected from 364 outpatients treated at an inner-city hospital. TOXO status was determined with an ELISA assay for TOXO-specific IgG. A discrete titer was calculated based on standard cut-points as an indicator of seropositivity, and the TOXO-specific IgG concentration served as serointensity. A series of linear regression models were used to assess the association of TOXO seropositivity and serointensity with ASR magnitude and latency in models adjusting for demographics and psychiatric diagnoses (PTSD, major depression, schizophrenia, psychosis, substance abuse). ASR magnitude was 11.5% higher in TOXO seropositive subjects compared to seronegative individuals (p=0.01). This effect was more pronounced in models with TOXO serointensity that adjusted for sociodemographic covariates (F=7.41, p=0.0068; F=10.05, p=0.0017), and remained significant when psychiatric diagnoses were stepped into the models. TOXO showed no association with

  9. Repeated low-dose exposures to sarin, soman, or VX affect acoustic startle in guinea pigs.

    PubMed

    Smith, C D; Lee, R B; Moran, A V; Sipos, M L

    2016-01-01

    Chemical warfare nerve agents (CWNAs) are known to cause behavioral abnormalities in cases of human exposures and in animal models. The behavioral consequences of single exposures to CWNAs that cause observable toxic signs are particularly well characterized in animals; however, less is known regarding repeated smaller exposures that may or may not cause observable toxic signs. In the current study, guinea pigs were exposed to fractions (0.1, 0.2, or 0.4) of a medial lethal dose (LD50) of sarin, soman, or VX for two weeks. On each exposure day, and for a post-exposure period, acoustic startle response (ASR) was measured in each animal. Although relatively few studies use guinea pigs to measure behavior, this species is ideal for CWNA-related experiments because their levels of carboxylesterases closely mimic those of humans, unlike rats or mice. Results showed that the 0.4 LD50 doses of soman and VX transiently increased peak startle amplitude by the second week of injections, with amplitude returning to baseline by the second week post-exposure. Sarin also increased peak startle amplitude independent of week. Latencies to peak startle and PPI were affected by agent exposure but not consistently among the three agents. Most of the changes in startle responses returned to baseline following the cessation of exposures. These data suggest that doses of CWNAs not known to produce observable toxic signs in guinea pigs can affect behavior in the ASR paradigm. Further, these deficits are transient and usually return to baseline shortly after the end of a two-week exposure period.

  10. Interactions Between Corticotropin-Releasing Factor and the Serotonin 1A Receptor System on Acoustic Startle Amplitude and Prepulse Inhibition of the Startle Response in Two Rat Strains

    PubMed Central

    Conti, Lisa H.

    2011-01-01

    Both the neuropeptide, corticotropin-releasing factor (CRF) and the serotonin 1A (5-HT1A) receptor systems have been implicated in anxiety disorders and there is evidence that the two systems interact with each other to affect behavior. Both systems have individually been shown to affect prepulse inhibition (PPI) of the acoustic startle response. PPI is a form of sensorimotor gating that is reduced in patients with anxiety disorders including post-traumatic stress and panic disorder. Here, we examined whether the two systems interact or counteract each other to affect acoustic startle amplitude, PPI and habituation of the startle response. In experiment 1, Brown Norway (BN) and Wistar-Kyoto (WKY) rats were administered ether an intraperitoneal (IP) injection of saline or the 5-HT1A receptor agonist, 8-OH-DPAT 10 min prior to receiving an intracerebroventricular (ICV) infusion of either saline or CRF (0.3 µg). In a second experiment, rats were administered either an IP injection of saline or the 5-HT1A receptor antagonist, WAY 100,635 10 min prior to receiving an ICV infusion of saline or CRF. Thirty min after the ICV infusion, the startle response and PPI were assessed. As we have previously shown, the dose of CRF used in these experiments reduced PPI in BN rats and had no effect on PPI in WKY rats. Administration of 8-OH-DPAT alone had no effect on PPI in either rat strain when the data from the two strains were examined separately. Administration of 8-OHDPAT added to the effect of CRF in BN rats, and the combination of 8-OH-DPAT and CRF significantly reduced PPI in WKY rats. CRF alone had no effect on baseline startle amplitude in either rat strain, but CRF enhanced the 8-OH-DPAT-induced increase in startle in both strains. Administration of WAY 100,635 did not affect the CRF-induced change in PPI and there were no interactions between CRF and WAY 100,635 on baseline startle. The results suggest that activation of the 5-HT1A receptor can potentiate the effect of

  11. Long-Lasting Suppression of Acoustic Startle Response after Mild Traumatic Brain Injury

    PubMed Central

    Sinha, Swamini; Avcu, Pelin; Roland, Jessica J.; Nadpara, Neil; Pfister, Bryan; Long, Mathew; Santhakumar, Vijayalakshmi; Servatius, Richard J.

    2015-01-01

    Abstract Acoustic startle response (ASR) is a defensive reflex that is largely ignored unless greatly exaggerated. ASR is suppressed after moderate and severe traumatic brain injury (TBI), but the effect of mild TBI (mTBI) on ASR has not been investigated. Because the neural circuitry for ASR resides in the pons in all mammals, ASR may be a good measure of brainstem function after mTBI. The present study assessed ASR in Sprague-Dawley rats after mTBI using lateral fluid percussion and compared these effects to those on spatial working memory. mTBI caused a profound, long-lasting suppression of ASR. Both probability of emitting a startle and startle amplitude were diminished. ASR suppression was observed as soon as 1 day after injury and remained suppressed for the duration of the study (21 days after injury). No indication of recovery was observed. mTBI also impaired spatial working memory. In contrast to the suppression of ASR, working memory impairment was transient; memory was impaired 1 and 7 days after injury, but recovered by 21 days. The long-lasting suppression of ASR suggests long-term dysfunction of brainstem neural circuits at a time when forebrain neural circuits responsible for spatial working memory have recovered. These results have important implications for return-to-activity decisions because recovery of cognitive impairments plays an important role in these decisions. PMID:25412226

  12. Long-lasting suppression of acoustic startle response after mild traumatic brain injury.

    PubMed

    Pang, Kevin C H; Sinha, Swamini; Avcu, Pelin; Roland, Jessica J; Nadpara, Neil; Pfister, Bryan; Long, Mathew; Santhakumar, Vijayalakshmi; Servatius, Richard J

    2015-06-01

    Acoustic startle response (ASR) is a defensive reflex that is largely ignored unless greatly exaggerated. ASR is suppressed after moderate and severe traumatic brain injury (TBI), but the effect of mild TBI (mTBI) on ASR has not been investigated. Because the neural circuitry for ASR resides in the pons in all mammals, ASR may be a good measure of brainstem function after mTBI. The present study assessed ASR in Sprague-Dawley rats after mTBI using lateral fluid percussion and compared these effects to those on spatial working memory. mTBI caused a profound, long-lasting suppression of ASR. Both probability of emitting a startle and startle amplitude were diminished. ASR suppression was observed as soon as 1 day after injury and remained suppressed for the duration of the study (21 days after injury). No indication of recovery was observed. mTBI also impaired spatial working memory. In contrast to the suppression of ASR, working memory impairment was transient; memory was impaired 1 and 7 days after injury, but recovered by 21 days. The long-lasting suppression of ASR suggests long-term dysfunction of brainstem neural circuits at a time when forebrain neural circuits responsible for spatial working memory have recovered. These results have important implications for return-to-activity decisions because recovery of cognitive impairments plays an important role in these decisions.

  13. Modulation of the N170 with Classical Conditioning: The Use of Emotional Imagery and Acoustic Startle in Healthy and Depressed Participants.

    PubMed

    Camfield, David A; Mills, Jessica; Kornfeld, Emma J; Croft, Rodney J

    2016-01-01

    Recent studies have suggested that classical conditioning may be capable of modulating early sensory processing in the human brain, and that there may be differences in the magnitude of the conditioned changes for individuals with major depressive disorder. The effect of conditioning on the N170 event-related potential was investigated using neutral faces as conditioned stimuli (CS+) and emotional imagery and acoustic startle as unconditioned stimuli (UCS). In the first experiment, electroencephalogram was recorded from 24 undergraduate students (M = 21.07 years, SD = 3.38 years) under the following conditions: (i) CS+/aversive imagery, (ii) CS+/aversive imagery and acoustic startle, (iii) CS+/acoustic startle, and (iv) CS+/pleasant imagery. The amplitude of the N170 was enhanced following conditioning with aversive imagery as well as acoustic startle. In the second experiment, 26 healthy control participants were tested (17 females and 9 males, age M = 25.97 years, SD = 9.42) together with 18 depressed participants (13 females and 5 males, age M = 23.26 years, SD = 4.01) and three conditions were used: CS+/aversive imagery, CS+/pleasant imagery, and CS-. N170 amplitude at P7 was increased for the CS+/aversive condition in comparison to CS- in the conditioning blocks versus baseline. No differences between depressed and healthy participants were found. Across both experiments, evaluative conditioning was absent. It was concluded that aversive UCS are capable of modulating early sensory processing of faces, although further research is also warranted in regards to positive UCS.

  14. Modulation of the N170 with Classical Conditioning: The Use of Emotional Imagery and Acoustic Startle in Healthy and Depressed Participants

    PubMed Central

    Camfield, David A.; Mills, Jessica; Kornfeld, Emma J.; Croft, Rodney J.

    2016-01-01

    Recent studies have suggested that classical conditioning may be capable of modulating early sensory processing in the human brain, and that there may be differences in the magnitude of the conditioned changes for individuals with major depressive disorder. The effect of conditioning on the N170 event-related potential was investigated using neutral faces as conditioned stimuli (CS+) and emotional imagery and acoustic startle as unconditioned stimuli (UCS). In the first experiment, electroencephalogram was recorded from 24 undergraduate students (M = 21.07 years, SD = 3.38 years) under the following conditions: (i) CS+/aversive imagery, (ii) CS+/aversive imagery and acoustic startle, (iii) CS+/acoustic startle, and (iv) CS+/pleasant imagery. The amplitude of the N170 was enhanced following conditioning with aversive imagery as well as acoustic startle. In the second experiment, 26 healthy control participants were tested (17 females and 9 males, age M = 25.97 years, SD = 9.42) together with 18 depressed participants (13 females and 5 males, age M = 23.26 years, SD = 4.01) and three conditions were used: CS+/aversive imagery, CS+/pleasant imagery, and CS-. N170 amplitude at P7 was increased for the CS+/aversive condition in comparison to CS- in the conditioning blocks versus baseline. No differences between depressed and healthy participants were found. Across both experiments, evaluative conditioning was absent. It was concluded that aversive UCS are capable of modulating early sensory processing of faces, although further research is also warranted in regards to positive UCS. PMID:27445773

  15. Age- and Sex-Dependent Effects of Footshock Stress on Subsequent Alcohol Drinking and Acoustic Startle Behavior in Mice Selectively Bred for High-Alcohol Preference

    PubMed Central

    Chester, Julia A.; Barrenha, Gustavo D.; Hughes, Matthew L.; Keuneke, Kelly J.

    2015-01-01

    Background Exposure to stress during adolescence is known to be a risk factor for alcohol-use and anxiety disorders. This study examined the effects of footshock stress during adolescence on subsequent alcohol drinking in male and female mice selectively bred for high-alcohol preference (HAP1 lines). Acoustic startle responses and prepulse inhibition (PPI) were also assessed in the absence of, and immediately following, subsequent footshock stress exposures to determine whether a prior history of footshock stress during adolescence would produce enduring effects on anxiety-related behavior and sensorimotor gating. Methods Alcohol-nav̈ve, adolescent (male, n = 27; female, n = 23) and adult (male, n = 30; female, n = 30) HAP1 mice were randomly assigned to a stress or no stress group. The study consisted of 5 phases: (1) 10 consecutive days of exposure to a 30-minute footshock session, (2) 1 startle test, (3) one 30-minute footshock session immediately followed by 1 startle test, (4) 30 days of free-choice alcohol consumption, and (5) one 30-minute footshock session immediately followed by 1 startle test. Results Footshock stress exposure during adolescence, but not adulthood, robustly increased alcohol drinking behavior in both male and female HAP1 mice. Before alcohol drinking, females in both the adolescent and adult stress groups showed greater startle in phases 2 and 3; whereas males in the adolescent stress group showed greater startle only in phase 3. After alcohol drinking, in phase 5, enhanced startle was no longer apparent in any stress group. Males in the adult stress group showed reduced startle in phases 2 and 5. PPI was generally unchanged, except that males in the adolescent stress group showed increased PPI in phase 3 and females in the adolescent stress group showed decreased PPI in phase 5. Conclusions Adolescent HAP1 mice appear to be more vulnerable to the effects of footshock stress than adult mice, as manifested by increased alcohol drinking

  16. Noise exposure during early development influences the acoustic startle reflex in adult rats.

    PubMed

    Rybalko, Natalia; Bureš, Zbyněk; Burianová, Jana; Popelář, Jiří; Grécová, Jolana; Syka, Josef

    2011-03-28

    Noise exposure during the critical period of postnatal development in rats results in anomalous processing of acoustic stimuli in the adult auditory system. In the present study, the behavioral consequences of an acute acoustic trauma in the critical period are assessed in adult rats using the acoustic startle reflex (ASR) and prepulse inhibition (PPI) of ASR. Rat pups (strain Long-Evans) were exposed to broad-band noise of 125 dB SPL for 8 min on postnatal day 14; at the age of 3-5 months, ASR and PPI of ASR were examined and compared with those obtained in age-matched controls. In addition, hearing thresholds were measured in all animals by means of auditory brainstem responses. The results show that although the hearing thresholds in both groups of animals were not different, a reduced strength of the startle reflex was observed in exposed rats compared with controls. The efficacy of PPI in exposed and control rats was also markedly different. In contrast to control rats, in which an increase in prepulse intensity was accompanied by a consistent increase in the efficacy of PPI, the PPI function in the exposed animals was characterized by a steep increase in inhibitory efficacy at low prepulse intensities of 20-30 dB SPL. A further increase of prepulse intensity up to 60-70 dB SPL caused only a small and insignificant change of PPI. Our findings demonstrate that brief noise exposure in rat pups results in altered behavioral responses to sounds in adulthood, indicating anomalies in intensity coding and loudness perception.

  17. Lesions of the paraventricular thalamic nucleus attenuates prepulse inhibition of the acoustic startle reflex.

    PubMed

    Öz, Pınar; Kaya Yertutanol, F Duygu; Gözler, Tayfun; Özçetin, Ayşe; Uzbay, I Tayfun

    2017-03-06

    The paraventricular thalamic nucleus (PVT) is a midline nucleus with strong connections to cortical and subcortical brain regions such as the prefrontal cortex, amygdala, nucleus accumbens and hippocampus and receives strong projections from brain stem nuclei. Prepulse inhibition (PPI) is mediated and modulated by complex cortical and subcortical networks that are yet to be fully identified in detail. Here, we suggest that the PVT may be an important brain region for the modulation of PPI. In our study, the paraventricular thalamic nuclei of rats were electrolytically lesioned. Two weeks after the surgery, the PPI responses of the animals were monitored and recorded using measurements of acoustic startle reflex. Our results show that disruption of the PVT dramatically attenuated PPI at prepulse intensities of 74, 78 and 86dB compared to that in the sham lesion group. Thus, we suggest that the PVT may be an important part of the PPI network in the rat brain.

  18. Nicotine withdrawal disrupts both foreground and background contextual fear conditioning but not pre-pulse inhibition of the acoustic startle response in C57BL/6 mice.

    PubMed

    André, Jessica M; Gulick, Danielle; Portugal, George S; Gould, Thomas J

    2008-07-19

    Nicotine withdrawal is associated with multiple symptoms such as anxiety, increased appetite, and disrupted cognition in humans. Although animal models have provided insights into the somatic and affective symptoms of nicotine withdrawal, less research has focused on the effects of nicotine withdrawal on cognition. Therefore, in this study, C57BL/6J mice were used to test the effects of withdrawal from chronic nicotine on foreground and background contextual fear conditioning, which present the context as a primary or secondary stimulus, respectively. Mice withdrawn from 12 days of chronic nicotine (6.3mg/kg/day) or saline were trained and tested in either foreground or background contextual fear conditioning; nicotine withdrawal-associated deficits in contextual fear conditioning were observed in both conditions. Mice were also tested for the effects of withdrawal on pre-pulse inhibition of the acoustic startle reflex (PPI), a measure of sensory gating, and on the acoustic startle reflex. Mice withdrawn from 12 days of chronic nicotine (6.3 or 12.6 mg/kg/day) or saline underwent one 30-min PPI and startle session; no effect of withdrawal from chronic nicotine on PPI or startle was observed for either dose at 24h after nicotine removal. Therefore, mice were tested at different time points following withdrawal from 12.6 mg/kg/day chronic nicotine (8, 24, and 48 h after nicotine removal). No effect of withdrawal from chronic nicotine was observed at any time point for PPI. Overall, these results demonstrate that nicotine withdrawal disrupts two methods of contextual learning but not sensory gating in C57BL/6J mice.

  19. Using a startling acoustic stimulus to investigate underlying mechanisms of bradykinesia in Parkinson's disease.

    PubMed

    Carlsen, Anthony N; Almeida, Quincy J; Franks, Ian M

    2013-02-01

    Delays in the initiation of a movement response and slowness during movement are among the hallmark motor symptoms in patients with Parkinson's disease (PD). These impairments may result from deficits in neural structures related to perception, response programming, response initiation, or a combination of all three. However, the relative impact of each process on movement control in PD is still unclear. The present study investigated which processes might be responsible for the observed slowness. Patients performed a simple reaction time (RT) task involving arm extension where the normal 82 dB acoustic "go" signal was unexpectedly replaced with a 124 dB startling acoustic stimulus (SAS) on selected trials. The SAS was used as a probe of motor preparatory state since it has been shown to act as a subcortically-mediated involuntarily trigger for actions that are sufficiently prepared and waiting to be initiated by normal cortical processes. It was expected that release of the voluntary response by startle would not occur in PD patients if bradykinetic symptoms were attributable primarily to motor programming deficits. In contrast, results clearly showed that when a SAS was presented, the prepared response was elicited at a significantly shorter latency. In addition, the amplitude and timing pattern of EMG output appeared to be improved compared to control, resulting in a faster, more normalized movement. These results suggest that in PD patients motor programming processes are relatively intact, while the dysfunctional basal ganglia likely assert an inhibitory effect on the thalamo-cortical connections responsible for the initiation of motor acts.

  20. Acoustic startle modification as a tool for evaluating auditory function of the mouse: Progress, pitfalls, and potential.

    PubMed

    Lauer, Amanda M; Behrens, Derik; Klump, Georg

    2017-03-19

    Acoustic startle response (ASR) modification procedures, especially prepulse inhibition (PPI), are increasingly used as behavioral measures of auditory processing and sensorimotor gating in rodents due to their perceived ease of implementation and short testing times. In practice, ASR and PPI procedures are extremely variable across animals, experimental setups, and studies, and the interpretation of results is subject to numerous caveats and confounding influences. We review considerations for modification of the ASR using acoustic stimuli, and we compare the sensitivity of PPI procedures to more traditional operant psychoacoustic techniques. We also discuss non-auditory variables that must be considered. We conclude that ASR and PPI measures cannot substitute for traditional operant techniques due to their low sensitivity. Additionally, a substantial amount of pilot testing must be performed to properly optimize an ASR modification experiment, negating any time benefit over operant conditioning. Nevertheless, there are some circumstances where ASR measures may be the only option for assessing auditory behavior, such as when testing mouse strains with early-onset hearing loss or learning impairments.

  1. Modality of fear cues affects acoustic startle potentiation but not heart-rate response in patients with dental phobia

    PubMed Central

    Wannemüller, André; Sartory, Gudrun; Elsesser, Karin; Lohrmann, Thomas; Jöhren, Hans P.

    2015-01-01

    The acoustic startle response (SR) has consistently been shown to be enhanced by fear-arousing cross-modal background stimuli in phobics. Intra-modal fear-potentiation of acoustic SR was rarely investigated and generated inconsistent results. The present study compared the acoustic SR to phobia-related sounds with that to phobia-related pictures in 104 dental phobic patients and 22 controls. Acoustic background stimuli were dental treatment noises and birdsong and visual stimuli were dental treatment and neutral control pictures. Background stimuli were presented for 4 s, randomly followed by the administration of the startle stimulus. In addition to SR, heart-rate (HR) was recorded throughout the trials. Irrespective of their content, background pictures elicited greater SR than noises in both groups with a trend for phobic participants to show startle potentiation to phobia-related pictures but not noises. Unlike controls, phobics showed HR acceleration to both dental pictures and noises. HR acceleration of the phobia group was significantly positively correlated with SR in the noise condition only. The acoustic SR to phobia-related noises is likely to be inhibited by prolonged sensorimotor gating. PMID:25774142

  2. Neurochemistry of the afferents to the rat cochlear root nucleus: Possible synaptic modulation of the acoustic startle

    PubMed Central

    Gómez-Nieto, R; Horta-Junior, JAC; Castellano, O; Herrero-Turrión, MJ; Rubio, ME; López, DE

    2008-01-01

    Afferents to the primary startle circuit are essential for the elicitation and modulation of the acoustic startle reflex (ASR). In the rat, cochlear root neurons (CRNs) comprise the first component of the acoustic startle circuit and play a crucial role in mediating the ASR. Nevertheless, the neurochemical pattern of their afferents remains unclear. To determine the distribution of excitatory and inhibitory inputs, we used confocal microscopy to analyze the immunostaining for vesicular glutamate and GABA transporter proteins (VGLUT1 and VGAT) on retrogradely labeled CRNs. We also used reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry to detect and localize specific neurotransmitter receptor subunits in the cochlear root. Our results show differential distributions of VGLUT1- and VGAT-immunoreactive endings around cell bodies and dendrites. The RT-PCR data showed a positive band for several ionotropic glutamate receptor subunits, M1- M5 muscarinic receptor subtypes, the glycine receptor α1 subunit (GlyRα1), GABAA, GABAB, and subunits of α2 and β-noradrenergic receptors. By immunohistochemistry, we confirmed that CRN cell bodies exhibit positive immunoreaction for the GluR3 and NR1 glutamate receptor subunits. Cell bodies and dendrites were also positive for M2 and M4, and GlyRα1. Other subunits, such as GluR1 and GluR4 of the AMPA glutamate receptors, were observed in glial cells neighboring unlabeled CRN cell bodies. We further confirmed the existence of noradrenergic afferents onto CRNs from the locus coeruleus by combining tyrosine hydroxylase immunohistochemistry and tract-tracing experiments. Our results provide valuable information toward understanding how CRNs might integrate excitatory and inhibitory inputs, and hence how they could elicit and modulate the acoustic startle reflex. PMID:18384963

  3. Tissue plasminogen activator in the bed nucleus of stria terminalis regulates acoustic startle.

    PubMed

    Matys, T; Pawlak, R; Strickland, S

    2005-01-01

    The bed nucleus of stria terminalis is a basal forebrain region involved in regulation of hormonal and behavioral responses to stress. In this report we demonstrate that bed nucleus of stria terminalis has a high and localized expression of tissue plasminogen activator, a serine protease with neuromodulatory properties and implicated in neuronal plasticity. Tissue plasminogen activator activity in the bed nucleus of stria terminalis is transiently increased in response to acute restraint stress or i.c.v. administration of a major stress mediator, corticotropin-releasing factor. We show that tissue plasminogen activator is important in bed nucleus of stria terminalis function using two criteria: 1, Neuronal activation in this region as measured by c-fos induction is reduced in tissue plasminogen activator-deficient mice; and 2, a bed nucleus of stria terminalis-dependent behavior, potentiation of acoustic startle by corticotropin-releasing factor, is attenuated in tissue plasminogen activator-deficient mice. These studies identify a novel site of tissue plasminogen activator expression in the mouse brain and demonstrate a functional role for this protease in the bed nucleus of stria terminalis.

  4. Changes in acoustic startle reflex in rats induced by playback of 22-kHz calls.

    PubMed

    Inagaki, Hideaki; Ushida, Takahiro

    2017-02-01

    In aversive or dangerous situations, adult rats emit long characteristic ultrasonic calls, often termed "22-kHz calls," which have been suggested to play a role of alarm calls. Although the playback experiment is one of the most effective ways to investigate the alarming properties of 22-kHz calls, clear behavioral evidence showing the anxiogenic effects of these playback stimuli has not been directly obtained to date. In this study, we investigated whether playback of 22-kHz calls or synthesized sine tones could change the acoustic startle reflex (ASR), enhancement of which is widely considered to be a reliable index of anxiety-related negative affective states in rats. Playback of 22-kHz calls significantly enhanced the ASR in rats. Enhancement effects caused by playback of 22-kHz calls from young rats were relatively weak compared to those after calls from adult rats. Playback of synthesized 25-kHz sine tones enhanced ASR in subjects, but not synthesized 60-kHz tones. Further, shortening the individual call duration of synthesized 25-kHz sine tones also enhanced the ASR. Accordingly, it is suggested that 22-kHz calls induce anxiety by socially communicated alarming signals in rats. The results also demonstrated that call frequency, i.e., of 22kHz, appears important for ultrasonic alarm-signal communication in rats.

  5. The Acoustic Startle Response and Disruption of Aiming. 2. Modulation by Forewarning and Preliminary Stimuli

    DTIC Science & Technology

    1989-11-01

    effective startle stimulus. Similarly, the startle reflex is attenuated by brief, irrele- ’ Requests for reprints should be addressed to James R. vant ...extreme responses, and for nine of these on perceptual-motor behavior, though Hoff - subjects the responses were nmore common on man and Fleshier (1963

  6. Effects of inescapable stress and treatment with pyridostigmine bromide on plasma butyrylcholinesterase and the acoustic startle response in rats.

    PubMed

    Servatius, R J; Ottenweller, J E; Guo, W; Beldowicz, D; Zhu, G; Natelson, B H

    2000-05-01

    Pyridostigmine bromide (PB) is a reversible, peripherally active inhibitor of acetylcholinesterase (AChE) activity, and is recommended by the military as a pretreatment against potential nerve gas exposure. Recent evidence suggests that exposure to inescapable stressors allows PB to cross the blood-brain barrier, and thereby affect central AChE activity in mice. Here, we evaluated the functional impact of a stress/PB treatment interaction on acoustic startle responding and plasma butyrylcholinesterase (BuChE) activity in male Sprague-Dawley rats. To model the treatment protocol used by the military, PB was delivered in the drinking water of rats for 7 consecutive days. The morning after the start of PB treatment, and for the next 6 days, half the rats were exposed to 1 h of supine restraint stress. We therefore employed a 2 x 2 (stress x PB treatment) between-groups design. Exposure to supine stress alone induced a persistent decrease in plasma BuChE activity. Further decreases in BuChE activity were not observed in rats exposed to supine restraint and PB treatment. Exposure to stress also induced an exaggerated startle response, evident on the last day of stress and 24 h after stressor cessation. Treatment with PB alone produced an exaggerated startle response over the same time period, albeit to a lesser degree. Although treatment with PB concurrent with stress did not produce further changes in either BuChE activity or acoustic startle responding, stress-induced alterations in drinking behavior (and thereby the dose of PB ingested) may have affected these results. Persistent stress-induced reductions in BuChE activity may increase the risk of adverse reactions to cholinomimetics.

  7. Stimulus quality affects expression of the acoustic startle response and prepulse inhibition in mice.

    PubMed

    Stoddart, C W; Noonan, J; Martin-Iverson, M T

    2008-06-01

    The relationship between stimulus intensity and startle response magnitude (SIRM) can assess the startle reflex and prepulse inhibition (PPI) with advantages over more commonly used methods. The current study used the SIRM relationships in mice to determine differences between white noise and pure tone (5 kHz) stimuli. Similarly to rats, the SIRM relationship showed a sigmoid pattern. The SIRM-derived reflex capacity (RMAX) and response efficacy (slope) of the white noise and pure tone stimuli in the absence of prepulses were equivalent. However, the pure tone startle response threshold (DMIN) was increased whereas the stimulus potency (1/ES50) was decreased when compared to white noise. Prepulses of both stimulus types inhibited RMAX and increased DMIN, but the white noise prepulses were more effective. Both stimulus intensity gating and motor capacity gating processes are shown to occur, dependent on prepulse intensity and stimulus onset asynchrony. Prepulse intensities greater than 10 dB below the startle threshold appear to produce PPI via stimulus intensity gating, whereas a motor capacity gating component appears at prepulse intensities near to the startle threshold.

  8. Acoustic startle and prepulse inhibition predict smoking lapse in posttraumatic stress disorder.

    PubMed

    Vrana, Scott R; Calhoun, Patrick S; Dennis, Michelle F; Kirby, Angela C; Beckham, Jean C

    2015-10-01

    Most smokers who attempt to quit lapse within the first week and are ultimately unsuccessful in their quit attempt. Nicotine withdrawal exacerbates cognitive and attentional problems and may be one factor in smoking relapse. The startle reflex response and prepulse inhibition (PPI) of the response are sensitive to arousal and early attentional dysregulation. The current study examined whether startle response and PPI are related to early smoking lapse, and if this differs in people with and without posttraumatic stress disorder (PTSD). Participants with (N = 34) and without (N = 57) PTSD completed a startle reflex and PPI assessment during (1) ad lib smoking (2) on the first day of abstinence during a quit attempt. Most (88%) participants lapsed within the first week of the quit attempt. PTSD status predicted shorter time to lapse. Larger startle magnitude and greater PPI predicted a longer duration before smoking lapse. When diagnostic groups were examined separately, greater PPI predicted a longer successful quit attempt only in participants with a PTSD diagnosis. The startle reflex response and PPI may provide an objective, neurophysiological evaluation of regulation of arousal and early attentional processes by nicotine, which are important factors in smoking cessation success.

  9. Structural and functional abnormalities of the hippocampal formation in rats with environmentally induced reductions in prepulse inhibition of acoustic startle.

    PubMed

    Greene, J R; Kerkhoff, J E; Guiver, L; Totterdell, S

    2001-01-01

    The effects of social isolation on prepulse inhibition of acoustic startle (PPI), electrophysiology and morphology of subicular pyramidal neurons and the densities of interneuronal sub-types in the hippocampal formation were examined. Wistar rats (male weanlings) were housed socially (socials, n=8) or individually (isolates, n=7). When tested eight weeks later, PPI was lower in isolates. Rats then received terminal anaesthesia before slices of hippocampal formation were made in which the electrophysiological properties of a total of 108 subicular neurons were characterized. There were no differences in neuronal sub-types recorded in socials compared with isolates. Intrinsically burst-firing and regular spiking pyramidal neurons were examined in detail. There were no differences in resting membrane potential or input resistance in isolates compared with socials but action potential height was reduced and action potential threshold raised in isolates. A limited morphological examination of Neurobiotin-filled intrinsically burst-firing neurons did not reveal differences in cell-body area or in number of primary dendrites. Sections from the contralateral hemispheres of the same rats were stained with antibodies to calretinin, parvalbumin and the neuronal isoform of nitric oxide synthase (nNOS). In isolates, the density of calretinin positive neurons was increased in the dentate gyrus but unchanged in areas CA3, CA1 and subiculum. Parvalbumin and nNOS positive neuronal densities were unchanged. Hence in rats with environmentally induced reductions in PPI there are structural and functional abnormalities in the hippocampal formation. If the reduction in PPI stems from these abnormalities, and reduced PPI in rats is relevant to schizophrenia, then drugs that correct the reported electrophysiological changes might have antipsychotic effects.

  10. Investigation of Stimulus-Response Compatibility Using a Startling Acoustic Stimulus

    ERIC Educational Resources Information Center

    Maslovat, Dana; Carlsen, Anthony N.; Franks, Ian M.

    2012-01-01

    We investigated the processes underlying stimulus-response compatibility by using a lateralized auditory stimulus in a simple and choice reaction time (RT) paradigm. Participants were asked to make either a left or right key lift in response to either a control (80dB) or startling (124dB) stimulus presented to either the left ear, right ear, or…

  11. Direct Field Acoustic Testing

    NASA Technical Reports Server (NTRS)

    Larkin, Paul; Goldstein, Bob

    2008-01-01

    This paper presents an update to the methods and procedures used in Direct Field Acoustic Testing (DFAT). The paper will discuss some of the recent techniques and developments that are currently being used and the future publication of a reference standard. Acoustic testing using commercial sound system components is becoming a popular and cost effective way of generating a required acoustic test environment both in and out of a reverberant chamber. This paper will present the DFAT test method, the usual setup and procedure and the development and use of a closed-loop, narrow-band control system. Narrow-band control of the acoustic PSD allows all standard techniques and procedures currently used in random control to be applied to acoustics and some examples are given. The paper will conclude with a summary of the development of a standard practice guideline that is hoped to be available in the first quarter of next year.

  12. Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Takahashi, Hidetoshi; Komatsu, Sahoko; Nakahachi, Takayuki; Ogino, Kazuo; Kamio, Yoko

    2016-01-01

    Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and…

  13. Effects of VX on Acoustic Startle Response and Acquisition of Operant Behavior in Rats

    DTIC Science & Technology

    2008-02-01

    marmosets . These studies indicate that for both guinea pigs and marmosets , startle reactions increase following exposure to soman. However, it appears...Those studies utilized rats, mice, guinea pigs or marmosets as experimental subjects. In light of the abundance of reports on the disruption of...efficacy of single or repeated HI-6 treatment following soman poisoning in guinea pigs and marmoset monkeys, Toxicology 112 (1996) 183-194. [9] E.K

  14. Social defeat stress produces prolonged alterations in acoustic startle and body weight gain in male Long Evans rats.

    PubMed

    Pulliam, John V K; Dawaghreh, Ahmad M; Alema-Mensah, Ernest; Plotsky, Paul M

    2010-01-01

    Individuals exposed to psychological stressors may experience a long-term resetting of behavioral and neuroendocrine aspects of their "stress response" so that they either hyper or hypo-respond to subsequent stressors. These effects of psychological or traumatic stressors may be mimicked in rats using the resident-intruder model of social defeat. The social defeat model has been characterized to model aspects of the physiology and behavior associated with anxiety and depression. The objective of this study was to determine if behaviors elicited following repeated social defeat can also reflect aspects of ethologically relevant stresses associated with existing post traumatic stress disorder (PTSD) models. Socially defeated rats displayed weight loss and an enhanced and prolonged response to acoustic startle which was displayed for up to 10days following repeated social defeat. These data indicate that the severe stress of social defeat can produce physiologic and behavioral outcomes which may reflect aspects of traumatic psychosocial stress.

  15. History of chronic stress modifies acute stress-evoked fear memory and acoustic startle in male rats.

    PubMed

    Schmeltzer, Sarah N; Vollmer, Lauren L; Rush, Jennifer E; Weinert, Mychal; Dolgas, Charles M; Sah, Renu

    2015-01-01

    Chronicity of trauma exposure plays an important role in the pathophysiology of posttraumatic stress disorder (PTSD). Thus, exposure to multiple traumas on a chronic scale leads to worse outcomes than acute events. The rationale for the current study was to investigate the effects of a single adverse event versus the same event on a background of chronic stress. We hypothesized that a history of chronic stress would lead to worse behavioral outcomes than a single event alone. Male rats (n = 14/group) were exposed to either a single traumatic event in the form of electric foot shocks (acute shock, AS), or to footshocks on a background of chronic stress (chronic variable stress-shock, CVS-S). PTSD-relevant behaviors (fear memory and acoustic startle responses) were measured following 7 d recovery. In line with our hypothesis, CVS-S elicited significant increases in fear acquisition and conditioning versus the AS group. Unexpectedly, CVS-S elicited reduced startle reactivity to an acoustic stimulus in comparison with the AS group. Significant increase in FosB/ΔFosB-like immunostaining was observed in the dentate gyrus, basolateral amygdala and medial prefrontal cortex of CVS-S rats. Assessments of neuropeptide Y (NPY), a stress-regulatory transmitter associated with chronic PTSD, revealed selective reduction in the hippocampus of CVS-S rats. Collectively, our data show that cumulative stress potentiates delayed fear memory and impacts defensive responding. Altered neuronal activation in forebrain limbic regions and reduced NPY may contribute to these phenomena. Our preclinical studies support clinical findings reporting worse PTSD outcomes stemming from cumulative traumatization in contrast to acute trauma.

  16. Memory for objects and startle responsivity in the immediate aftermath of exposure to the Trier Social Stress Test.

    PubMed

    Herten, Nadja; Pomrehn, Dennis; Wolf, Oliver T

    2017-03-14

    Previously, we observed enhanced long-term memory for objects used (central objects) by committee members in the Trier Social Stress Test (TSST) on the next day. In addition, startle responsivity was increased. However, response specificity to an odour involved in the stressful episode was lacking and recognition memory for the odour was poor. In the current experiments, immediate effects of the stressor on memory and startle responsivity were investigated. We hypothesised memory for central objects of the stressful episode and startle response specificity to an odour ambient during the TSST to be enhanced shortly after it, in contrast to the control condition (friendly TSST). Further, memory for this odour was also assumed to be increased in the stress group. We tested 70 male (35) and female participants using the TSST involving objects and an ambient odour. After stress induction, a startle paradigm including olfactory and visual stimuli was conducted. Indeed, memory for central objects was significantly enhanced in immediate aftermath of the stressor. Startle responsivity increased at a trend level, particularly with regard to the odour involved in the stressful episode. Moreover, the stress group descriptively tended towards a better recognition of the odour involved. The study shows that stress enhances memory for central aspects of a stressful situation before consolidation processes come into play. In addition, results preliminarily suggest that the impact of stress on startle responsivity increases in strength but decreases in specificity during the first 24h after stress exposure.

  17. Effects of cold pressor stress on the human startle response.

    PubMed

    Deuter, Christian E; Kuehl, Linn K; Blumenthal, Terry D; Schulz, André; Oitzl, Melly S; Schachinger, Hartmut

    2012-01-01

    Both emotion and attention are known to influence the startle response. Stress influences emotion and attention, but the impact of stress on the human startle response remains unclear. We used an established physiological stressor, the Cold Pressor Test (CPT), to induce stress in a non-clinical human sample (24 student participants) in a within-subjects design. Autonomic (heart rate and skin conductance) and somatic (eye blink) responses to acoustic startle probes were measured during a pre-stress baseline, during a three minutes stress intervention, and during the subsequent recovery period. Startle skin conductance and heart rate responses were facilitated during stress. Compared to baseline, startle eye blink responses were not affected during the intervention but were diminished afterwards. These data describe a new and unique startle response pattern during stress: facilitation of autonomic stress responses but no such facilitation of somatic startle eye blink responses. The absence of an effect of stress on startle eye blink responsiveness may illustrate the importance of guaranteeing uninterrupted visual input during periods of stress.

  18. Effects of Cold Pressor Stress on the Human Startle Response

    PubMed Central

    Deuter, Christian E.; Kuehl, Linn K.; Blumenthal, Terry D.; Schulz, André; Oitzl, Melly S.; Schachinger, Hartmut

    2012-01-01

    Both emotion and attention are known to influence the startle response. Stress influences emotion and attention, but the impact of stress on the human startle response remains unclear. We used an established physiological stressor, the Cold Pressor Test (CPT), to induce stress in a non-clinical human sample (24 student participants) in a within-subjects design. Autonomic (heart rate and skin conductance) and somatic (eye blink) responses to acoustic startle probes were measured during a pre-stress baseline, during a three minutes stress intervention, and during the subsequent recovery period. Startle skin conductance and heart rate responses were facilitated during stress. Compared to baseline, startle eye blink responses were not affected during the intervention but were diminished afterwards. These data describe a new and unique startle response pattern during stress: facilitation of autonomic stress responses but no such facilitation of somatic startle eye blink responses. The absence of an effect of stress on startle eye blink responsiveness may illustrate the importance of guaranteeing uninterrupted visual input during periods of stress. PMID:23166784

  19. Atypical antipsychotic clozapine reversed deficit on prepulse inhibition of the acoustic startle reflex produced by microinjection of DOI into the inferior colliculus in rats.

    PubMed

    de Oliveira, Rodolpho Pereira; Nagaishi, Karen Yuriko; Barbosa Silva, Regina Cláudia

    2017-05-15

    Dysfunctions of the serotonergic system have been suggested to be important in the neurobiology of schizophrenia. Patients with schizophrenia exhibit deficits in an operational measure of sensorimotor gating: prepulse inhibition (PPI) of startle. PPI is the normal reduction in the startle response caused by a low intensity non-startling stimulus (prepulse) which is presented shortly before the startle stimulus (pulse). The hallucinogen 2,5-dimethoxy-4-iodoamphetamine (DOI), a 5-hydroxytryptamine(HT)2 receptor agonist disrupted PPI in rats. The inferior colliculus (IC) is a critical nucleus of the auditory pathway mediating acoustic PPI. The activation of the IC by the acoustic prepulse reduces startle magnitude. The present study investigated the role of serotonergic transmission in the IC on the expression of acoustic PPI. For that we investigated whether 5-HT2A receptor activation or blockade would affect this response. Unilateral microinjection of DOI (10μg/0.3μl) into the IC disrupted PPI, while microinjection of the 5-HT2A receptor antagonist ritanserin (4μg/0.3μl), into this structure did not alter PPI. We also examined the ability of the atypical antipsychotic clozapine (5.0mg/kg; I.P.) to reverse the disruption of PPI produced by unilateral microinjections of DOI into the IC of rats. Pretreatment with clozapine blocked DOI-induced disruption of PPI. Altogether, these results suggest that serotonin-mediated mechanisms of the IC are involved in the expression of PPI in rodents and that this response is sensitive to atypical antipsychotic clozapine.

  20. Gap-Prepulse Inhibition of the Acoustic Startle Reflex (GPIAS) for Tinnitus Assessment: Current Status and Future Directions

    PubMed Central

    Galazyuk, Alexander; Hébert, Sylvie

    2015-01-01

    The progress in the field of tinnitus largely depends on the development of a reliable tinnitus animal model. Recently, a new method based on the acoustic startle reflex modification was introduced for tinnitus screening in laboratory animals. This method was enthusiastically adopted and now widely used by many scientists in the field due to its seeming simplicity and a number of advantages over the other methods of tinnitus assessment. Furthermore, this method opened an opportunity for tinnitus assessment in humans as well. Unfortunately, multiple modifications of data collection and interpretation implemented in different labs make comparisons across studies very difficult. In addition, recent animal and human studies have challenged the original “filling-in” interpretation of the paradigm. Here, we review the current literature to emphasize on the commonalities and differences in data collection and interpretation across laboratories that are using this method for tinnitus assessment. We also propose future research directions that could be taken in order to establish whether or not this method is warranted as an indicator of the presence of tinnitus. PMID:25972836

  1. The medial septum mediates impairment of prepulse inhibition of acoustic startle induced by a hippocampal seizure or phencyclidine.

    PubMed

    Ma, Jingyi; Shen, Bixia; Rajakumar, N; Leung, L Stan

    2004-11-05

    The involvement of the septohippocampal system on the impaired sensorimotor gating induced by phencyclidine (PCP) or by an electrically induced hippocampal seizure was examined in behaving rats. An impaired sensorimotor gating, measured by prepulse inhibition (PPI) of the acoustic startle response, was observed following a hippocampal afterdischarge (AD) or systemic injection of PCP and was accompanied with an increase in hippocampal gamma waves (30-70 Hz). The medial septum infusion with muscimol (0.25 microg), a GABA(A) receptor agonist, 15 min prior to PCP or a hippocampal AD, prevented the impairment of sensorimotor gating and the increase in gamma waves. By itself, muscimol (0.25 microg) injection into the medial septum did not affect PPI, although it significantly suppressed spontaneous gamma waves. In order to identify subpopulations of neurons mediating the sensorimotor gating deficit and the hippocampal gamma wave increase, 0.14-0.21 microg of p75 antibody conjugated to saporin (192 IgG-saporin) was injected into the medial septum to selectively lesion the septohippocampal cholinergic neurons. Neither the PPI deficit nor the gamma wave increase induced by PCP or a hippocampal AD was affected by 192 IgG-saporin lesion of the medial septum. It is concluded that increase in neural activity in the medial septum participates in the impairment of sensorimotor gating and the increase in hippocampal gamma waves induced by PCP or a hippocampal AD. It is suggested that the GABAergic but not the cholinergic septohippocampal neurons mediate the sensorimotor gating deficit.

  2. Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys

    PubMed Central

    Henry, Porche’ Kirkland; Davis, Michael

    2009-01-01

    Rationale The transition from infrequent and controlled cocaine use to dependence may involve enduring changes in neurobiology as a consequence of persistent drug use. Objective The present study utilized an intravenous drug self-administration protocol of increasing cocaine access to evaluate potential changes in dopamine function in vivo, including changes in sensitivity to psychostimulants. Materials and methods Drug-naïve rhesus monkeys were provided limited access (1 h) to cocaine self-administration for 60 days followed by 60 days under an extended access condition (4 h). Basal levels of striatal extracellular dopamine and its metabolites, as well as the effectiveness of cocaine and amphetamine to elevate dopamine, were determined with in vivo microdialysis before the initiation of cocaine self-administration and during limited and extended access. The effect of cocaine and amphetamine on the acoustic startle response was also examined to assess complementary behavioral changes as a function of drug history. Results Extended access to cocaine self-administration lead to increased daily intake compared to limited access conditions but did not result in escalated intake over time. However, cocaine- and amphetamine-induced increases in striatal dopamine were diminished as a function of cocaine self-administration history. Surprisingly, there was no effect of drug-taking history on sensitivity to psychostimulant-induced enhancement of startle amplitude. Conclusions The present experiments provide evidence of a hypofunctional dopamine system that is not associated with an escalation in drug intake or reflected in measures of acoustic startle. PMID:19365621

  3. Behavioral consequences of radiation exposure to simulated space radiation in the C57BL/6 mouse: open field, rotorod, and acoustic startle

    NASA Technical Reports Server (NTRS)

    Pecaut, Michael J.; Haerich, Paul; Zuccarelli, Cara N.; Smith, Anna L.; Zendejas, Eric D.; Nelson, Gregory A.

    2002-01-01

    Two experiments were carried out to investigate the consequences of exposure to proton radiation, such as might occur for astronauts during space flight. C57BL/6 mice were exposed, either with or without 15-g/cm2 aluminum shielding, to 0-, 3-, or 4-Gy proton irradiation mimicking features of a solar particle event. Irradiation produced transient direct deficits in open-field exploratory behavior and acoustic startle habituation. Rotorod performance at 18 rpm was impaired by exposure to proton radiation and was impaired at 26 rpm, but only for mice irradiated with shielding and at the 4-Gy dose. Long-term (>2 weeks) indirect deficits in open-field activity appeared as a result of impaired experiential encoding immediately following exposure. A 2-week recovery prior to testing decreased most of the direct effects of exposure, with only rotorod performance at 26 rpm being impaired. These results suggest that the performance deficits may have been mediated by radiation damage to hippocampal, cerebellar, and possibly, forebrain dopaminergic function.

  4. Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders.

    PubMed

    Takahashi, Hidetoshi; Komatsu, Sahoko; Nakahachi, Takayuki; Ogino, Kazuo; Kamio, Yoko

    2016-02-01

    Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and more prolonged peak startle-latency. We could not find significant difference of prepulse inhibition (PPI) or habituation in ASD children compared to TD. However, habituation and PPI at 70-dB prepulses were negatively related to several subscales of Social Responsiveness Scale and the Strengths and Difficulties Questionnaire, when considering all children. Comprehensive investigation of ASR and its modulation might increase understanding of the neurophysiological impairments underlying ASD and other mental health problems in children.

  5. Immobility and hyperthermia in the tail suspension test: association with the Porsolt test and the reflex startle reaction in 11 inbred mouse strains and the effects of genetic knockout of MAO A.

    PubMed

    Popova, N K; Tibeikina, M A

    2010-06-01

    Immobility and hyperthermia induced by unavoidable stress imposed by the tail suspension test (TST) and the acoustic startle reaction were assessed in mice of 11 inbred strains and in Tg8 mice, which have genetic knockout of MAO A. Sharp genotypic differences in immobility were seen, while there was no correlation with the hyperthermic response to the TST. A correlation was found between the extent of immobility in the TST and the startle reaction. Studies of 11 strains of mice revealed a positive correlation between the duration of immobility in the TST and the Porsolt "despair test." Genetic knockout of MAO A, one of the key enzymes in catecholamine and serotonin metabolism in the brain, weakened the startle reaction and TST-induced hyperthermia but had no significant effect on the immobility of Tg8 mice, which provides evidence of differences in the neurochemical regulation of these reactions. These data provide grounds for using the TST as a "dry" Porsolt test and identify TST-induced hyperthermia as a model for reactions to unavoidable stress.

  6. Different Effects of Startling Acoustic Stimuli (SAS) on TMS-Induced Responses at Rest and during Sustained Voluntary Contraction.

    PubMed

    Chen, Yen-Ting; Li, Shengai; Zhou, Ping; Li, Sheng

    2016-01-01

    Previous studies have shown that a habituated startling acoustic stimulus (SAS) can cause a transient suppression of motor evoked potentials (MEPs) induced by transcranial magnetic stimulation (TMS) during light muscle contraction. However, it is still unknown whether this phenomenon persists when at rest or during a sustained voluntary contraction task. Therefore, the purpose of this study was to determine whether a conditioning SAS has different effects. TMS was delivered to the hot spot for the left biceps on 11 subjects at rest both with and without a conditioning SAS. Of the 11subjects, 9 also had TMS delivered during isometric flexion of the left elbow, also with and without a conditioning SAS. TMS-induced MEPs, TMS-induced force, and silent periods were used to determine the effect of conditioning SAS. Consistent with previous findings, TMS-induced MEPs were smaller with a conditioning SAS (0.49 ± 0.37 mV) as compared without the SAS (0.69 ± 0.52 mV) at rest. However, a conditioning SAS during the voluntary contraction tasks resulted in a significant shortening of the MEP silent period (187.22 ± 22.99 ms with SAS vs. 200.56 ± 29.71 ms without SAS) without any changes in the amplitude of the MEP (1.37 ± 0.9 mV with SAS V.S. 1.32 ± 0.92 mV without SAS) or the TMS-induced force (3.11 ± 2.03 N-m with SAS V.S. 3.62 ± 1.33 N-m without SAS). Our results provide novel evidence that a conditioning SAS has different effects on the excitability of the motor cortex when at rest or during sustained voluntary contractions.

  7. Different Effects of Startling Acoustic Stimuli (SAS) on TMS-Induced Responses at Rest and during Sustained Voluntary Contraction

    PubMed Central

    Chen, Yen-Ting; Li, Shengai; Zhou, Ping; Li, Sheng

    2016-01-01

    Previous studies have shown that a habituated startling acoustic stimulus (SAS) can cause a transient suppression of motor evoked potentials (MEPs) induced by transcranial magnetic stimulation (TMS) during light muscle contraction. However, it is still unknown whether this phenomenon persists when at rest or during a sustained voluntary contraction task. Therefore, the purpose of this study was to determine whether a conditioning SAS has different effects. TMS was delivered to the hot spot for the left biceps on 11 subjects at rest both with and without a conditioning SAS. Of the 11subjects, 9 also had TMS delivered during isometric flexion of the left elbow, also with and without a conditioning SAS. TMS-induced MEPs, TMS-induced force, and silent periods were used to determine the effect of conditioning SAS. Consistent with previous findings, TMS-induced MEPs were smaller with a conditioning SAS (0.49 ± 0.37 mV) as compared without the SAS (0.69 ± 0.52 mV) at rest. However, a conditioning SAS during the voluntary contraction tasks resulted in a significant shortening of the MEP silent period (187.22 ± 22.99 ms with SAS vs. 200.56 ± 29.71 ms without SAS) without any changes in the amplitude of the MEP (1.37 ± 0.9 mV with SAS V.S. 1.32 ± 0.92 mV without SAS) or the TMS-induced force (3.11 ± 2.03 N-m with SAS V.S. 3.62 ± 1.33 N-m without SAS). Our results provide novel evidence that a conditioning SAS has different effects on the excitability of the motor cortex when at rest or during sustained voluntary contractions. PMID:27547181

  8. Oxytocin reduces background anxiety in a fear-potentiated startle paradigm: peripheral vs central administration.

    PubMed

    Ayers, Luke W; Missig, Galen; Schulkin, Jay; Rosen, Jeffrey B

    2011-11-01

    Oxytocin is known to have anti-anxiety and anti-stress effects. Using a fear-potentiated startle paradigm in rats, we previously demonstrated that subcutaneously administered oxytocin suppressed acoustic startle following fear conditioning compared with startle before fear conditioning (termed background anxiety), but did not have an effect on cue-specific fear-potentiated startle. The findings suggest oxytocin reduces background anxiety, an anxious state not directly related to cue-specific fear, but sustained beyond the immediate threat. The goal of the present study was to compare the effects of centrally and peripherally administered oxytocin on background anxiety and cue-specific fear. Male rats were given oxytocin either subcutaneously (SC) or intracerebroventricularly (ICV) into the lateral ventricles before fear-potentiated startle testing. Oxytocin doses of 0.01 and 0.1 μg/kg SC reduced background anxiety. ICV administration of oxytocin at doses from 0.002 to 20 μg oxytocin had no effect on background anxiety or cue-specific fear-potentiated startle. The 20 μg ICV dose of oxytocin did reduce acoustic startle in non-fear conditioned rats. These studies indicate that oxytocin is potent and effective in reducing background anxiety when delivered peripherally, but not when delivered into the cerebroventricular system. Oxytocin given systemically may have anti-anxiety properties that are particularly germane to the hypervigilance and exaggerated startle typically seen in many anxiety and mental health disorder patients.

  9. Responses to startling acoustic stimuli indicate that movement-related activation is constant prior to action: a replication with an alternate interpretation

    PubMed Central

    Maslovat, Dana; Franks, Ian M; Leguerrier, Alexandra; Carlsen, Anthony N

    2015-01-01

    A recent study by Marinovic et al. (J. Neurophysiol., 2013, 109: 996–1008) used a loud acoustic stimulus to probe motor preparation in a simple reaction time (RT) task. Based on decreasing RT latency and increases in motor output measures as the probe stimulus approached the “go” stimulus, the authors concluded that response-related activation increased abruptly 65 ms prior to the imperative stimulus, a result in contrast to previous literature. However, this study did not measure reflexive startle activity in the sternocleidomastoid (SCM) muscle, which has been used to delineate between response triggering by a loud acoustic stimuli and effects of stimulus intensity and/or intersensory facilitation. Due to this methodological limitation, it was unclear if the data accurately represented movement-related activation changes. In order to provide a measure as to whether response triggering occurred on each trial, the current experiment replicated the study by Marinovic et al., with the collection of muscle activation in the SCM. While the replication analyses involving all trials confirmed similar results to those reported by Marinovic et al., when data were limited to those in which startle-related SCM activation occurred, the results indicated that movement-related activation is constant in the 65 ms prior to action initiation. The difference between analyses suggests that when SCM activation is not considered, results may be confounded by trials in which the probe stimulus does not trigger the prepared response. Furthermore, these results provide additional confirmation that reflexive startle activation in the SCM is a robust indicator of response triggering by a loud acoustic stimulus. PMID:25663524

  10. Dynamics of intracellular dopamine contents in the rat brain during the formation of conditioned contextual fear and extinction of an acoustic startle reaction.

    PubMed

    Storozheva, Z I; Afanas'ev, I I; Proshin, A T; Kudrin, V S

    2003-05-01

    Extracellular dopamine contents in the caudate nucleus, nucleus accumbens, and prefrontal cortex of the rat brain were measured during two sessions of extinction of an acoustic startle reaction--each consisting of ten sound stimuli, the two sessions separated by 24 h--with simultaneous recording of freezing behavior. The results demonstrated a decrease in extracellular dopamine levels in the caudate nucleus and an increase in the nucleus accumbens during both sessions of extinction, with return to initial immediately after sessions ended. During the second session, the amplitude of startle responses and the magnitude of changes in dopamine levels in both structures were significantly smaller than during the first session. Between the sessions, dopamine levels in the caudate nucleus remained constant, while those in the nucleus accumbens decreased. The prefrontal cortex showed increases in dopamine levels during both sessions of extinction, as well as between the two sessions. The amplitude of the startle reaction was found to correlate with dopamine levels in the prefrontal cortex after the end of the corresponding extinction session and with the dopamine level before the start of the second session. The freezing time before the start of sound stimulation in the second session, this being a measure of conditioned fear, correlated with the dopamine level in the caudate nucleus on the training day and with the dopamine level in the nucleus accumbens before the start of the second session. The role of the dopaminergic system in the mechanisms forming and realizing the various components of defensive behavior are discussed.

  11. Morphological correlates of sex differences in acoustic startle response and prepulse inhibition through projections from locus coeruleus to cochlear root neurons.

    PubMed

    Hormigo, Sebastian; Gómez-Nieto, Ricardo; Sancho, Consuelo; Herrero-Turrión, Javier; Carro, Juan; López, Dolores E; Horta-Júnior, José de Anchieta de Castro E

    2017-04-05

    The noradrenergic locus coeruleus (LC) plays an important role in the promotion and maintenance of arousal and alertness. Our group recently described coerulean projections to cochlear root neurons (CRNs), the first relay of the primary acoustic startle reflex (ASR) circuit. However, the role of the LC in the ASR and its modulation, prepulse inhibition (PPI), is not clear. In this study, we damaged LC neurons and fibers using a highly selective neurotoxin, DSP-4, and then assessed ASR and PPI in male and female rats. Our results showed that ASR amplitude was higher in males at 14 days after DSP-4 injection when compared to pre-administration values and those in the male control group. Such modifications in ASR amplitude did not occur in DSP-4-injected females, which exhibited ASR amplitude within the range of control values. PPI differences between males and females seen in controls were not observed in DSP-4-injected rats for any interstimulus interval tested. DSP-4 injection did not affect ASR and PPI latencies in either the male or the female groups, showing values that were consistent with the sex-related variability observed in control rats. Furthermore, we studied the noradrenergic receptor system in the cochlear nerve root using gene expression analysis. When compared to controls, DSP-4-injected males showed higher levels of expression in all adrenoceptor subtypes; however, DSP-4-injected females showed varied effects depending on the receptor type, with either up-, downregulations, or maintenance of expression levels. Lastly, we determined noradrenaline levels in CRNs and other LC-targeted areas using HPLC assays, and these results correlated with behavioral and adrenoceptor expression changes post DSP-4 injection. Our study supports the participation of LC in ASR and PPI, and contributes toward a better understanding of sex-related differences observed in somatosensory gating paradigms.

  12. Electronic dummy for acoustical testing

    NASA Technical Reports Server (NTRS)

    Bauer, B. B.; Di Mattia, A. L.; Rosencheck, A. J.; Stern, M.; Torick, E. L.

    1967-01-01

    Electronic Dummy /ED/ used for acoustical testing represents the average male torso from the Xiphoid process upward and includes an acoustic replica of the human head. This head simulates natural flesh, and has an artificial voice and artificial ears that measure sound pressures at the eardrum or the entrance to the ear canal.

  13. Acoustic Climb to Cruise Test

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Flight test film footage of three different aircraft testing the acoustical noise levels during take-off, climb, maneuvers, and touch and go landings are described. These sound tests were conducted on two fighter aircraft and one cargo aircraft. Results from mobile test vehicle are shown.

  14. Cytotoxic lesion of the medial prefrontal cortex abolishes the partial reinforcement extinction effect, attenuates prepulse inhibition of the acoustic startle reflex and induces transient hyperlocomotion, while sparing spontaneous object recognition memory in the rat.

    PubMed

    Yee, B K

    2000-01-01

    The partial reinforcement extinction effect refers to the increase in resistance to extinction of an operant response acquired under partial reinforcement relative to that acquired under continuous reinforcement. Prepulse inhibition of the acoustic startle response refers to the reduction in startle reactivity towards an intense acoustic pulse stimulus when it is shortly preceded by a weak prepulse stimulus. These two behavioural phenomena appear to be related to different forms of attentional processes. While the prepulse inhibition effect reflects an inherent early attentional gating mechanism, the partial reinforcement extinction effect is believed to involve the development of acquired inattention, i.e. the latter requires the animals to learn about what to and what not to attend. Impairments in prepulse inhibition and the partial reinforcement extinction effect have been independently linked to the neuropsychology of attentional dysfunctions seen in schizophrenia. The proposed neural substrates underlying these behaviourial phenomena also appear to overlap considerably: both focus on the nucleus accumbens and emphasize the functional importance of its limbic afferents, including that originating from the medial prefrontal cortex, on accumbal output/activity. The present study demonstrated that cytotoxic medial prefrontal cortex lesions which typically damaged the prelimbic, the infralimbic and the dorsal anterior cingulate areas could lead to the abolition of the partial reinforcement extinction effect and the attenuation of prepulse inhibition. The lesions also resulted in a transient elevation of spontaneous locomotor activity. In contrast, the same lesions spared performance in a spontaneous object recognition memory test, in which the lesioned animals displayed normal preference for a novel object when the novel object was presented in conjunction with a familiar object seen 10 min earlier within an open field arena. The present results lend support to the

  15. Acoustically Induced Vibration of Structures: Reverberant Vs. Direct Acoustic Testing

    NASA Technical Reports Server (NTRS)

    Kolaini, Ali R.; O'Connell, Michael R.; Tsoi, Wan B.

    2009-01-01

    Large reverberant chambers have been used for several decades in the aerospace industry to test larger structures such as solar arrays and reflectors to qualify and to detect faults in the design and fabrication of spacecraft and satellites. In the past decade some companies have begun using direct near field acoustic testing, employing speakers, for qualifying larger structures. A limited test data set obtained from recent acoustic tests of the same hardware exposed to both direct and reverberant acoustic field testing has indicated some differences in the resulting structural responses. In reverberant acoustic testing, higher vibration responses were observed at lower frequencies when compared with the direct acoustic testing. In the case of direct near field acoustic testing higher vibration responses appeared to occur at higher frequencies as well. In reverberant chamber testing and direct acoustic testing, standing acoustic modes of the reverberant chamber or the speakers and spacecraft parallel surfaces can strongly couple with the fundamental structural modes of the test hardware. In this paper data from recent acoustic testing of flight hardware, that yielded evidence of acoustic standing wave coupling with structural responses, are discussed in some detail. Convincing evidence of the acoustic standing wave/structural coupling phenomenon will be discussed, citing observations from acoustic testing of a simple aluminum plate. The implications of such acoustic coupling to testing of sensitive flight hardware will be discussed. The results discussed in this paper reveal issues with over or under testing of flight hardware that could pose unanticipated structural and flight qualification issues. Therefore, it is of paramount importance to understand the structural modal coupling with standing acoustic waves that has been observed in both methods of acoustic testing. This study will assist the community to choose an appropriate testing method and test setup in

  16. Solid Rocket Motor Acoustic Testing

    SciTech Connect

    Rogers, J.D.

    1999-03-31

    Acoustic data are often required for the determination of launch and powered flight loads for rocket systems and payloads. Such data are usually acquired during test firings of the solid rocket motors. In the current work, these data were obtained for two tests at a remote test facility where we were visitors. This paper describes the data acquisition and the requirements for working at a remote site, interfacing with the test hosts.

  17. Behavioral and pharmacological validation of an integrated fear-potentiated startle and prepulse inhibition paradigm.

    PubMed

    Zhang, Mengjiao; Li, Ming

    2016-07-01

    Fear-potentiated startle (FPS) and prepulse inhibition (PPI) of acoustic startle are two widely used paradigms specifically designed to capture the impact of negative emotion (e.g. fear) and preattentive function on startle response. Currently, there is no single paradigm that incorporates both FPS and PPI, making it impossible to examine the potential interactions between fear and attention in the regulation of startle response. In this study, we developed an integrated FPS and PPI test protocol and validated it with psychoactive drugs. In Experiment 1, male Sprague-Dawley rats were randomly assigned to one of five groups, receiving either Light -Shock conditioning trials, non-overlapping Lights and Shocks, Light alone, Shock alone, or no Light and Shock. They were then tested for startle response and PPI concurrently, under the Light or No Light. FPS was observed only in rats subjected to fear conditioning, whereas all rats showed PPI and startle habituation. Experiment 2 used this paradigm and demonstrated a dissociative effect between diazepam (an anxiolytic drug) and phencyclidine (a nonselective NMDA receptor antagonist) on FPS and PPI. Diazepam suppressed both FPS and PPI, while PCP selectively disrupted PPI but not FPS. The diazepam's anxiolytic effect on FPS was further confirmed in the elevated plus maze test. Together, our findings indicate that our paradigm combines FPS and PPI into a single paradigm, and that is useful to examine potential interactions between multiple psychological processes, to identify the common neural substrates and to screen new drugs with multiple psychoactive effects.

  18. Startle modulation before, during and after exposure to emotional stimuli.

    PubMed

    Dichter, Gabriel S; Tomarken, Andrew J; Baucom, Brian R

    2002-02-01

    Although affective modulation of the startle reflex is a highly replicable effect, the majority of studies have administered startle probes during exposure to affective stimuli. To examine more comprehensively the temporal course of startle potentiation, we assessed blink modulation before, during and immediately after exposure to positive, negative and neutral pictures. During each trial, cues about the affective content of pictures were presented, after which acoustic startle probes were delivered either before picture onset, during picture onset or immediately after picture offset. As expected, we observed a linear relation between picture valence and startle amplitude during picture viewing. Surprisingly, startle amplitude was larger while anticipating pleasant and unpleasant pictures relative to neutral pictures. No significant effects were observed during the offset phase. These results indicate that startle modulation is conditional upon temporal factors linked to stimulus onset and offset.

  19. Between Site Reliability of Startle Prepulse Inhibition Across Two Early Psychosis Consortia

    PubMed Central

    Addington, Jean; Cannon, Tyrone D.; Cornblatt, Barbara A.; de la Fuente-Sandoval, Camilo; Mathalon, Dan H.; Perkins, Diana O.; Seidman, Larry J.; Tsuang, Ming; Walker, Elaine F.; Woods, Scott W.; Bachman, Peter; Belger, Ayse; Carrión, Ricardo E.; Donkers, Franc C.L.; Duncan, Erica; Johannesen, Jason; León-Ortiz, Pablo; Light, Gregory; Mondragón, Alejandra; Niznikiewicz, Margaret; Nunag, Jason; Roach, Brian J.; Solís-Vivanco, Rodolfo

    2014-01-01

    Prepulse inhibition (PPI) and reactivity of the acoustic startle response are widely used biobehavioral markers in psychopathology research. Previous studies have demonstrated that PPI and startle reactivity exhibit substantial within-site stability; between-site stability, however, has not been established. In two separate consortia investigating biomarkers of early psychosis, traveling subjects studies were performed as part of quality assurance procedures in order to assess the fidelity of data across sites. In the North American Prodromal Longitudinal Studies (NAPLS) Consortium, 8 normal subjects traveled to each of the 8 NAPLS sites and were tested twice at each site on the startle PPI paradigm. In preparation for a binational study, 10 healthy subjects were assessed twice in both San Diego and Mexico City. Intraclass correlations between and within sites were significant for PPI and startle response parameters, confirming the reliability of startle measures across sites in both consortia. There were between site differences in startle magnitude in the NAPLS study that did not appear to be related to methods or equipment. In planning multi-site studies, it is essential to institute quality assurance procedures early and establish between site reliability to assure comparable data across sites. PMID:23799460

  20. Cardiac Modulation of Startle: Effects on Eye Blink and Higher Cognitive Processing

    ERIC Educational Resources Information Center

    Schulz, Andre; Reichert, Carolin F.; Richter, Steffen; Lass-Hennemann, Johanna; Blumenthal, Terry D.; Schachinger, Hartmut

    2009-01-01

    Cardiac cycle time has been shown to affect pre-attentive brainstem startle processes, such as the magnitude of acoustically evoked reflexive startle eye blinks. These effects were attributed to baro-afferent feedback mechanisms. However, it remains unclear whether cardiac cycle time plays a role in higher startle-related cognitive processes, as…

  1. Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC.

    PubMed

    Vorhees, Charles V; Graham, Devon L; Braun, Amanda A; Schaefer, Tori L; Skelton, Matthew R; Richtand, Neil M; Williams, Michael T

    2012-08-01

    Prenatal maternal immune activation has been used to test the neurodevelopmental hypothesis of schizophrenia. Most of the data are in mouse models; far less is available for rats. We previously showed that maternal weight change in response to the immune activator polyinosinic-polycytidylic acid (Poly IC) in rats differentially affects offspring. Therefore, we treated gravid Harlan Sprague-Dawley rats i.p. on embryonic day 14 with 8 mg/kg of Poly IC or Saline. The Poly IC group was divided into those that lost or gained the least weight, Poly IC (L), versus those that gained the most weight, Poly IC (H), following treatment. The study design controlled for litter size, litter sampling, sex distribution, and test experience. We found no effects of Poly IC on elevated zero maze, open-field activity, object burying, light-dark test, straight channel swimming, Morris water maze spatial acquisition, reversal, or shift navigation or spatial working or reference memory, or conditioned contextual or cued fear or latent inhibition. The Poly IC (H) group showed a significant decrease in the rate of route-based learning when visible cues were unavailable in the Cincinnati water maze and reduced prepulse inhibition of acoustic startle in females, but not males. The Poly IC (L) group exhibited altered responses to acute pharmacological challenges: exaggerated hyperactivity in response to (+)-amphetamine and an attenuated hyperactivity in response to MK-801. This model did not exhibit the cognitive, or latent inhibition deficits reported in Poly IC-treated rats but showed changes in response to drugs acting on neurotransmitter systems implicated in the pathophysiology of schizophrenia (dopaminergic hyperfunction and glutamatergic hypofunction).

  2. Direct Field and Reverberant Chamber Acoustic Test Comparisons

    NASA Technical Reports Server (NTRS)

    OConnell, Michael

    2007-01-01

    Reverberant and direct acoustic test comparisons were analyzed in this viewgraph presentation. The acoustic test data set includes: 1) CloudSat antenna subjected to PF reverberant chamber acoustic test; 2) CloudSat subjected to a PF direct speaker acoustic test; and 3) DAWN flight spacecraft subjected to PF direct speaker and a workmanship reverberant chamber acoustic test.

  3. Startle Modulation Studies in Autism.

    ERIC Educational Resources Information Center

    Ornitz, Edward M.; And Others

    1993-01-01

    Analysis of 54 autistic patients and 72 controls found no intergroup differences in startle modulation by inhibitory or facilitatory prestimulation, short-term habituation of startle amplitude, long-term habituation of startle amplitude or latency, or unmodulated startle amplitude. Differences included prolongation of unmodulated startle onset…

  4. How many blinks are necessary for a reliable startle response? A test using the NPU-threat task.

    PubMed

    Lieberman, Lynne; Stevens, Elizabeth S; Funkhouser, Carter J; Weinberg, Anna; Sarapas, Casey; Huggins, Ashley A; Shankman, Stewart A

    2017-04-01

    Emotion-modulated startle is a frequently used method in affective science. Although there is a growing literature on the reliability of this measure, it is presently unclear how many startle responses are necessary to obtain a reliable signal. The present study therefore evaluated the reliability of startle responding as a function of number of startle responses (NoS) during a widely used threat-of-shock paradigm, the NPU-threat task, in a clinical (N=205) and non-clinical (N=92) sample. In the clinical sample, internal consistency was also examined independently for healthy controls vs. those with panic disorder and/or major depression and retest reliability was assessed as a function of NoS. Although results varied somewhat by diagnosis and for retest reliability, the overall pattern of results suggested that six startle responses per condition were necessary to obtain acceptable reliability in clinical and non-clinical samples during this threat-of-shock paradigm in the present study.

  5. Reverberant Acoustic Testing and Direct Field Acoustic Testing Acoustic Standing Waves and their Impact on Structural Responses

    NASA Technical Reports Server (NTRS)

    Kolaini, Ali R.; Doty, Benjamin; Chang, Zensheu

    2012-01-01

    The aerospace industry has been using two methods of acoustic testing to qualify flight hardware: (1) Reverberant Acoustic Test (RAT), (2) Direct Field Acoustic Test (DFAT). The acoustic field obtained by RAT is generally understood and assumed to be diffuse, expect below Schroeder cut-of frequencies. DFAT method of testing has some distinct advantages over RAT, however the acoustic field characteristics can be strongly affected by test setup such as the speaker layouts, number and location of control microphones and control schemes. In this paper the following are discussed based on DEMO tests performed at APL and JPL: (1) Acoustic wave interference patterns and acoustic standing waves, (2) The structural responses in RAT and DFAT.

  6. The CRH1 antagonist GSK561679 increases human fear but not anxiety as assessed by startle.

    PubMed

    Grillon, Christian; Hale, Elizabeth; Lieberman, Lynne; Davis, Andrew; Pine, Daniel S; Ernst, Monique

    2015-03-13

    Fear to predictable threat and anxiety to unpredictable threat reflect distinct processes mediated by different brain structures, the central nucleus of the amygdala and the bed nucleus of the stria terminalis (BNST), respectively. This study tested the hypothesis that the corticotropin-releasing factor (CRF1) antagonist GSK561679 differentially reduces anxiety but increases fear in humans. A total of 31 healthy females received each of four treatments: placebo, 50 mg GSK561679 (low-GSK), 400 mg GSK561679 (high-GSK), and 1 mg alprazolam in a crossover design. Participants were exposed to three conditions during each of the four treatments. The three conditions included one in which predictable aversive shocks were signaled by a cue, a second during which shocks were administered unpredictably, and a third condition without shock. Fear and anxiety were assessed using the acoustic startle reflex. High-GSK had no effect on startle potentiation during unpredictable threat (anxiety) but increased startle potentiation during the predictable condition (fear). Low-GSK did not affect startle potentiation across conditions. Consistent with previous findings, alprazolam reduced startle potentiation during unpredictable threat but not during predictable threat. The increased fear by high-GSK replicates animal findings and suggests a lift of the inhibitory effect of the BNST on the amygdala by the CRF1 antagonist.

  7. Involvement of pallidotegmental neurons in methamphetamine- and MK-801-induced impairment of prepulse inhibition of the acoustic startle reflex in mice: reversal by GABAB receptor agonist baclofen.

    PubMed

    Arai, Sawako; Takuma, Kazuhiro; Mizoguchi, Hiroyuki; Ibi, Daisuke; Nagai, Taku; Takahashi, Kenji; Kamei, Hiroyuki; Nabeshima, Toshitaka; Yamada, Kiyofumi

    2008-12-01

    We have previously demonstrated that pallidotegmental GABAergic neurons play a crucial role in prepulse inhibition (PPI) of the startle reflex in mice through the activation of GABA(B) receptors in pedunculopontine tegmental neurons. In this study, we investigated whether PPI disruption induced by methamphetamine (METH) or MK-801 is associated with the dysfunction of pallidotegmental neurons. Furthermore, we examined the effects of baclofen, a GABA(B) receptor agonist, on METH- and MK-801-induced PPI impairment. Acute treatment with METH (3 mg/kg, subcutaneouly (s.c.)) and MK-801 (>0.3 mg/kg, s.c.) significantly disrupted PPI, accompanied by the suppression of c-Fos expression in lateral globus pallidus induced by PPI. Furthermore, acute treatment with METH and MK-801 stimulated c-Fos expression in the caudal pontine reticular nucleus (PnC) in mice subjected to the PPT test, although PPI alone had no effect on c-Fos expression. Repeated treatment with 1 mg/kg METH for 7 days, which did not affect PPI acutely, showed similar effects on PPI and c-Fos expression to acute treatment with METH (3 mg/kg). Baclofen dose-dependently ameliorated PPI impairment induced by acute treatment with METH (3 mg/kg) and MK-801 (1 mg/kg), and decreased METH- and MK-801-stimulated c-Fos expression in PnC to the basal level. These results suggest that dysfunction of pallidotegmental neurons is involved in PPI disruption caused by METH and MK-801 in mice. GABA(B) receptor may constitute a putative target in treating neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia and METH psychosis.

  8. Amygdala and anterior cingulate cortex activation during affective startle modulation: a PET study of fear.

    PubMed

    Pissiota, Anna; Frans, Orjan; Michelgård, Asa; Appel, Lieuwe; Långström, Bengt; Flaten, Magne Arve; Fredrikson, Mats

    2003-09-01

    The human startle response is modulated by emotional experiences, with startle potentiation associated with negative affect. We used positron emission tomography with 15O-water to study neural networks associated with startle modulation by phobic fear in a group of subjects with specific snake or spider phobia, but not both, during exposure to pictures of their feared and non-feared objects, paired and unpaired with acoustic startle stimuli. Measurement of eye electromyographic activity confirmed startle potentiation during the phobic as compared with the non-phobic condition. Employing a factorial design, we evaluated brain correlates of startle modulation as the interaction between startle and affect, using the double subtraction contrast (phobic startle vs. phobic alone) vs. (non-phobic startle vs. non-phobic alone). As a result of startle potentiation, a significant increase in regional cerebral blood flow was found in the left amygdaloid-hippocampal region, and medially in the affective division of the anterior cingulate cortex (ACC). These results provide evidence from functional brain imaging for a modulatory role of the amygdaloid complex on startle reactions in humans. They also point to the involvement of the affective ACC in the processing of startle stimuli during emotionally aversive experiences. The co-activation of these areas may reflect increased attention to fear-relevant stimuli. Thus, we suggest that the amygdaloid area and the ACC form part of a neural system dedicated to attention and orientation to danger, and that this network modulates startle during negative affect.

  9. Startle reduces recall of a recently learned internal model.

    PubMed

    Wright, Zachary; Patton, James L; Ravichandran, Venn

    2011-01-01

    Recent work has shown that preplanned motor programs are released early from subcortical areas by the using a startling acoustic stimulus (SAS). Our question is whether this response might also contain a recently learned internal model, which draws on experience to predict and compensate for expected perturbations in a feedforward manner. Studies of adaptation to robotic forces have shown some evidence of this, but were potentially confounded by cocontraction caused by startle. We performed a new adaptation experiment using a visually distorted field that could not be confounded by cocontraction. We found that in all subjects that exhibited startle, the startle stimulus (1) reduced performance of the recently learned task (2) reduced after-effect magnitudes. Because startle reduced but did not eliminate the recall of learned control, we suggest that multiple neural centers (cortical and subcortical) are involved in such learning and adaptation, which can impact training areas such as piloting, teleoperation, sports, and rehabilitation.

  10. Impaired conditioned fear response and startle reactivity in epinephrine-deficient mice.

    PubMed

    Toth, Mate; Ziegler, Michael; Sun, Ping; Gresack, Jodi; Risbrough, Victoria

    2013-02-01

    Norepinephrine and epinephrine signaling is thought to facilitate cognitive processes related to emotional events and heightened arousal; however, the specific role of epinephrine in these processes is less known. To investigate the selective impact of epinephrine on arousal and fear-related memory retrieval, mice unable to synthesize epinephrine (phenylethanolamine N-methyltransferase knockout, PNMT-KO) were tested for contextual and cued-fear conditioning. To assess the role of epinephrine in other cognitive and arousal-based behaviors these mice were also tested for acoustic startle, prepulse inhibition, novel object recognition, and open-field activity. Our results show that compared with wild-type mice, PNMT-KO mice showed reduced contextual fear but normal cued fear. Mice exhibited normal memory performance in the short-term version of the novel object recognition task, suggesting that PNMT mice exhibit more selective memory effects on highly emotional and/or long-term memories. Similarly, open-field activity was unaffected by epinephrine deficiency, suggesting that differences in freezing are not related to changes in overall anxiety or exploratory drive. Startle reactivity to acoustic pulses was reduced in PNMT-KO mice, whereas prepulse inhibition was increased. These findings provide further evidence for a selective role of epinephrine in contextual-fear learning and support its potential role in acoustic startle.

  11. Respiratory modulation of startle eye blink: a new approach to assess afferent signals from the respiratory system.

    PubMed

    Schulz, André; Schilling, Thomas M; Vögele, Claus; Larra, Mauro F; Schächinger, Hartmut

    2016-11-19

    Current approaches to assess interoception of respiratory functions cannot differentiate between the physiological basis of interoception, i.e. visceral-afferent signal processing, and the psychological process of attention focusing. Furthermore, they typically involve invasive procedures, e.g. induction of respiratory occlusions or the inhalation of CO2-enriched air. The aim of this study was to test the capacity of startle methodology to reflect respiratory-related afferent signal processing, independent of invasive procedures. Forty-two healthy participants were tested in a spontaneous breathing and in a 0.25 Hz paced breathing condition. Acoustic startle noises of 105 dB(A) intensity (50 ms white noise) were presented with identical trial frequency at peak and on-going inspiration and expiration, based on a new pattern detection method, involving the online processing of the respiratory belt signal. The results show the highest startle magnitudes during on-going expiration compared with any other measurement points during the respiratory cycle, independent of whether breathing was spontaneous or paced. Afferent signals from slow adapting phasic pulmonary stretch receptors may be responsible for this effect. This study is the first to demonstrate startle modulation by respiration. These results offer the potential to apply startle methodology in the non-invasive testing of interoception-related aspects in respiratory psychophysiology.This article is part of the themed issue 'Interoception beyond homeostasis: affect, cognition and mental health'.

  12. Acoustic Test Characterization of Melamine Foam for Usage in NASA's Payload Fairing Acoustic Attenuation Systems

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Anne M.; McNelis, Mark E.

    2014-01-01

    The external acoustic liftoff levels predicted for NASA's future heavy lift launch vehicles are expected to be significantly higher than the environment created by today's commercial launch vehicles. This creates a need to develop an improved acoustic attenuation system for future NASA payload fairings. NASA Glenn Research Center initiated an acoustic test series to characterize the acoustic performance of melamine foam, with and without various acoustic enhancements. This testing was denoted as NEMFAT, which stands for NESC Enhanced Melamine Foam Acoustic Test, and is the subject of this paper. Both absorption and transmission loss testing of numerous foam configurations were performed at the Riverbank Acoustical Laboratory in July 2013. The NEMFAT test data provides an initial acoustic characterization and database of melamine foam for NASA. Because of its acoustic performance and lighter mass relative to fiberglass blankets, melamine foam is being strongly considered for use in the acoustic attenuation systems of NASA's future launch vehicles.

  13. Modeling startle eyeblink electromyogram to assess fear learning.

    PubMed

    Khemka, Saurabh; Tzovara, Athina; Gerster, Samuel; Quednow, Boris B; Bach, Dominik R

    2017-02-01

    Pavlovian fear conditioning is widely used as a laboratory model of associative learning in human and nonhuman species. In this model, an organism is trained to predict an aversive unconditioned stimulus from initially neutral events (conditioned stimuli, CS). In humans, fear memory is typically measured via conditioned autonomic responses or fear-potentiated startle. For the latter, various analysis approaches have been developed, but a systematic comparison of competing methodologies is lacking. Here, we investigate the suitability of a model-based approach to startle eyeblink analysis for assessment of fear memory, and compare this to extant analysis strategies. First, we build a psychophysiological model (PsPM) on a generic startle response. Then, we optimize and validate this PsPM on three independent fear-conditioning data sets. We demonstrate that our model can robustly distinguish aversive (CS+) from nonaversive stimuli (CS-, i.e., has high predictive validity). Importantly, our model-based approach captures fear-potentiated startle during fear retention as well as fear acquisition. Our results establish a PsPM-based approach to assessment of fear-potentiated startle, and qualify previous peak-scoring methods. Our proposed model represents a generic startle response and can potentially be used beyond fear conditioning, for example, to quantify affective startle modulation or prepulse inhibition of the acoustic startle response.

  14. Modeling startle eyeblink electromyogram to assess fear learning

    PubMed Central

    Khemka, Saurabh; Tzovara, Athina; Gerster, Samuel; Quednow, Boris B.

    2016-01-01

    Abstract Pavlovian fear conditioning is widely used as a laboratory model of associative learning in human and nonhuman species. In this model, an organism is trained to predict an aversive unconditioned stimulus from initially neutral events (conditioned stimuli, CS). In humans, fear memory is typically measured via conditioned autonomic responses or fear‐potentiated startle. For the latter, various analysis approaches have been developed, but a systematic comparison of competing methodologies is lacking. Here, we investigate the suitability of a model‐based approach to startle eyeblink analysis for assessment of fear memory, and compare this to extant analysis strategies. First, we build a psychophysiological model (PsPM) on a generic startle response. Then, we optimize and validate this PsPM on three independent fear‐conditioning data sets. We demonstrate that our model can robustly distinguish aversive (CS+) from nonaversive stimuli (CS‐, i.e., has high predictive validity). Importantly, our model‐based approach captures fear‐potentiated startle during fear retention as well as fear acquisition. Our results establish a PsPM‐based approach to assessment of fear‐potentiated startle, and qualify previous peak‐scoring methods. Our proposed model represents a generic startle response and can potentially be used beyond fear conditioning, for example, to quantify affective startle modulation or prepulse inhibition of the acoustic startle response. PMID:27753123

  15. Acoustic impedance testing for aeroacoustic applications

    NASA Astrophysics Data System (ADS)

    Schultz, Todd

    Accurate acoustic propagation models are required to characterize and subsequently reduce aircraft engine noise. These models ultimately rely on acoustic impedance measurements of candidate materials used in sound-absorbing liners. The standard two-microphone method (TMM) is widely used to estimate acoustic impedance but is limited in frequency range and does not provide uncertainty estimates, which are essential for data quality assessment and model validation. This dissertation presents a systematic framework to estimate uncertainty and extend the frequency range of acoustic impedance testing. Uncertainty estimation for acoustic impedance data using the TMM is made via two methods. The first employs a standard analytical technique based on linear perturbations and provides useful scaling information. The second uses a Monte Carlo technique that permits the propagation of arbitrarily large uncertainties. Both methods are applied to the TMM for simulated data representative of sound-hard and sound-soft acoustic materials. The results indicate that the analytical technique can lead to false conclusions about the magnitude and importance of specific error sources. Furthermore, the uncertainty in acoustic impedance is strongly dependent on the frequency and the uncertainty in the microphone locations. Next, an increased frequency range of acoustic impedance testing is investigated via two methods. The first method reduces the size of the test specimen (from 25.4 mm square to 8.5 mm square) and uses the standard TMM. This method has issues concerning specimen nonuniformity because the small specimens may not be representative of the material. The second method increases the duct cross section and, hence, the required complexity of the sound field propagation model. A comparison among all three methods is conducted for each of the three specimens: two different ceramic tubular specimens and a single degree-of-freedom liner. The results show good agreement between the

  16. Impact of Acoustic Standing Waves on Structural Responses: Reverberant Acoustic Testing (RAT) vs. Direct Field Acoustic Testing (DFAT)

    NASA Technical Reports Server (NTRS)

    Kolaini, Ali R.; Doty, Benjamin; Chang, Zensheu

    2012-01-01

    Loudspeakers have been used for acoustic qualification of spacecraft, reflectors, solar panels, and other acoustically responsive structures for more than a decade. Limited measurements from some of the recent speaker tests used to qualify flight hardware have indicated significant spatial variation of the acoustic field within the test volume. Also structural responses have been reported to differ when similar tests were performed using reverberant chambers. To address the impact of non-uniform acoustic field on structural responses, a series of acoustic tests were performed using a flat panel and a 3-ft cylinder exposed to the field controlled by speakers and repeated in a reverberant chamber. The speaker testing was performed using multi-input-single-output (MISO) and multi-input-multi-output (MIMO) control schemes with and without the test articles. In this paper the spatial variation of the acoustic field due to acoustic standing waves and their impacts on the structural responses in RAT and DFAT (both using MISO and MIMO controls for DFAT) are discussed in some detail.

  17. Tuned Chamber Core Panel Acoustic Test Results

    NASA Technical Reports Server (NTRS)

    Schiller, Noah H.; Allen, Albert R.

    2016-01-01

    This report documents acoustic testing of tuned chamber core panels, which can be used to supplement the low-frequency performance of conventional acoustic treatment. The tuned chamber core concept incorporates low-frequency noise control directly within the primary structure and is applicable to sandwich constructions with a directional core, including corrugated-, truss-, and fluted-core designs. These types of sandwich structures have long, hollow channels (or chambers) in the core. By adding small holes through one of the facesheets, the hollow chambers can be utilized as an array of low-frequency acoustic resonators. These resonators can then be used to attenuate low-frequency noise (below 400 Hz) inside a vehicle compartment without increasing the weight or size of the structure. The results of this test program demonstrate that the tuned chamber core concept is effective when used in isolation or combined with acoustic foam treatments. Specifically, an array of acoustic resonators integrated within the core of the panels was shown to improve both the low-frequency absorption and transmission loss of the structure in targeted one-third octave bands.

  18. Why do caterpillars whistle at birds? Insect defence sounds startle avian predators.

    PubMed

    Dookie, Amanda L; Young, Courtney A; Lamothe, Gilles; Schoenle, Laura A; Yack, Jayne E

    2017-05-01

    Many insects produce sounds when attacked by a predator, yet the functions of these signals are poorly understood. It is debated whether such sounds function as startle, warning or alarm signals, or merely serve to augment other defences. Direct evidence is limited owing to difficulties in disentangling the effects of sounds from other defences that often occur simultaneously in live insects. We conducted an experiment to test whether an insect sound can function as a deimatic (i.e. startle) display. Variations of a whistle of the walnut sphinx caterpillar (Amorpha juglandis) were presented to a predator, red-winged blackbirds (Agelaius phoeniceus), when birds activated a sensor while feeding on mealworms (Tenebrio molitor). Birds exposed to whistles played back at natural sound levels exhibited significantly higher startle scores (by flying away, flinching, and hopping) and took longer to return to the feeding dish than during control conditions where no sounds were played. Birds habituated to sounds during a one-hour session, but after two days the startling effects were restored. Our results provide empirical evidence that an insect sound alone can function as a deimatic display against an avian predator. We discuss how whistles might be particularly effective 'acoustic eye spots' on avian predators.

  19. Post Test Evaluation of HSCT Nozzle Acoustic Liner Subcomponents Subjected to a Hot Acoustic Durability Test

    NASA Technical Reports Server (NTRS)

    Verrilli, Michael J.; Lee, Kuan

    2008-01-01

    The acoustic liner system designed for use in the High Speed Civil Transport (HSCT) was tested in a thermal-acoustic environment. Five ceramic matrix composite (CMC) acoustic tile configurations, five bulk acoustic absorbers, and one thermal protection system design were tested. The CMC acoustic tiles were subjected to two 2 3/4 hr ambient temperature acoustic exposures to measure their dynamic response. One exposure was conducted on the tiles alone and the second exposure included the tiles and the T-foam bulk absorber. The measured tile RMS strains were small. With or without the T-foam absorber, the dynamic strains were below strain levels that would cause damage during fatigue loading. After the ambient exposure, a 75-hr durability test of the entire acoustic liner system was conducted using a thermal-acoustic cycle that approximated the anticipated service cycle. Acoustic loads up to 139 dB/Hz and temperatures up to 1670 F (910 C) were employed during this 60 cycle test. During the durability test, the CMC tiles were exposed to temperatures up to 1780 F and a transient through thickness gradient up to 490 F. The TPS peak temperatures on the hot side of the panels ranged from 750 to 1000 F during the 60 cycles. The through thickness delta T ranged from 450 to 650 F, varying with TPS location and cycle number. No damage, such as cracks or chipping, was observed in the CMC tiles after completion of the testing. However, on tile warped during the durability test and was replaced after 43 or 60 cycles. No externally observed damage was found in this tile. No failure of the CMC fasteners occurred, but damage was observed. Cracks and missing material occurred, only in the fastener head region. No indication of damage was observed in the T-foam acoustic absorbers. The SiC foam acoustic absorber experienced damage after about 43 cycles. Cracking in the TPS occurred around the attachment holes and under a vent. In spite of the development of damage, the TPS maintained

  20. The Neurotensin-1 Receptor Agonist PD149163 Blocks Fear-Potentiated Startle

    PubMed Central

    Shilling, Paul D.; Feifel, David

    2014-01-01

    Preliminary evidence suggests that the neuropeptide, neurotensin (NT) may regulate fear/anxiety circuits. We investigated the effects of PD149163, a NT-1 receptor agonist, on fear-potentiated startle (FPS). Sprague Dawley rats were trained to associate a white light with a mild foot shock. In one experiment, animals were treated with either subcutaneous vehicle or PD149163 (0.01, 0.1 or 1.0 mg/kg) twenty-four hours after training. Twenty minutes later their acoustic startle response in the presence or absence of the white light was tested. In a second experiment, saline and 1.0 mg/kg PD149163 were tested using a separate group of rats. In the first experiment, PD149163 produced a non-significant decrease in baseline acoustic startle at all three doses. As expected, saline treated rats exhibited significant FPS. An ANOVA of percentage FPS revealed no significant effect of treatment group overall but the high dose group did not display FPS strongly suggesting an FPS effect at this dose. This finding was confirmed in the second experiment where the high dose of PD149163 reduced percent FPS relative to saline (P<0.05). These data suggest that systemically administered NT-1 agonists modulate the neural circuitry that regulates fear and anxiety to produce dose-dependent anxiolytic-like effects on FPS. PMID:18577396

  1. Acoustic testing of high temperature panels

    NASA Technical Reports Server (NTRS)

    Leatherwood, Jack D.; Clevenson, Sherman A.; Powell, Clemans A.; Daniels, Edward F.

    1990-01-01

    Results are presented of a series of thermal-acoustic tests conducted on the NASA Langley Research Center Thermal-Acoustic Test Apparatus to (1) investigate techniques for obtaining strain measurements on metallic and carbon-carbon materials at elevated temperature; (2) document the dynamic strain response characteristics of several superalloy honeycomb thermal protection system panels at elevated temperatures of up to 1200 F; and (3) determine the strain response and sonic fatigue behavior of four carbon-carbon panels at both ambient and elevated temperatures. A second study tested four carbon-carbon panels to document panel dynamic response characteristics at ambient and elevated temperature, determine time to failure and faliure modes, and collect continuous strain data up to panel failure. Strain data are presented from both types of panels, and problems encountered in obtaining reliable strain data on the carbon-carbon panels are described. The failure modes of the carbon-carbon panels are examined.

  2. The gap-startle paradigm for tinnitus screening in animal models: limitations and optimization.

    PubMed

    Lobarinas, Edward; Hayes, Sarah H; Allman, Brian L

    2013-01-01

    In 2006, Turner and colleagues (Behav. Neurosci., 120:188-195) introduced the gap-startle paradigm as a high-throughput method for tinnitus screening in rats. Under this paradigm, gap detection ability was assessed by determining the level of inhibition of the acoustic startle reflex produced by a short silent gap inserted in an otherwise continuous background sound prior to a loud startling stimulus. Animals with tinnitus were expected to show impaired gap detection ability (i.e., lack of inhibition of the acoustic startle reflex) if the background sound containing the gap was qualitatively similar to the tinnitus pitch. Thus, for the gap-startle paradigm to be a valid tool to screen for tinnitus, a robust startle response from which to inhibit must be present. Because recent studies have demonstrated that the acoustic startle reflex could be dramatically reduced following noise exposure, we endeavored to 1) modify the gap-startle paradigm to be more resilient in the presence of hearing loss, and 2) evaluate whether a reduction in startle reactivity could confound the interpretation of gap prepulse inhibition and lead to errors in screening for tinnitus. In the first experiment, the traditional broadband noise (BBN) startle stimulus was replaced by a bandpass noise in which the sound energy was concentrated in the lower frequencies (5-10 kHz) in order to maintain audibility of the startle stimulus after unilateral high-frequency noise exposure (16 kHz). However, rats still showed a 57% reduction in startle amplitude to the bandpass noise post-noise exposure. A follow-up experiment on a separate group of rats with transiently-induced conductive hearing loss revealed that startle reactivity was better preserved when the BBN startle stimulus was replaced by a rapid airpuff to the back of the rat's neck. Furthermore, it was found that transient unilateral conductive hearing loss, which was not likely to induce tinnitus, caused an impairment in gap prepulse

  3. SLS Scale Model Acoustic Test Liftoff Results and Comparisons

    NASA Technical Reports Server (NTRS)

    Houston, Janice; Counter, Douglas; Giacomoni, Clothilde

    2015-01-01

    The liftoff phase induces acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are then used in the prediction of internal vibration responses of the vehicle and components which result in the qualification levels. Thus, predicting these liftoff acoustic (LOA) environments is critical to the design requirements of any launch vehicle. If there is a significant amount of uncertainty in the predictions or if acoustic mitigation options must be implemented, a subscale acoustic test is a feasible design phase test option to verify the LOA environments. The NASA Space Launch System (SLS) program initiated the Scale Model Acoustic Test (SMAT) to verify the predicted SLS LOA environments.

  4. Verification of Ares I Liftoff Acoustic Environments via the Ares I Scale Model Acoustic Test

    NASA Technical Reports Server (NTRS)

    Counter, Douglas; Houston, Janice

    2012-01-01

    The Ares I Scale Model Acoustic Test (ASMAT) program was implemented to verify the predicted Ares I liftoff acoustic environments and to determine the acoustic reduction gained by using an above deck water sound suppression system. The test article included a 5% scale Ares I vehicle model and Mobile Launcher with tower. Acoustic and pressure data were measured by over 200 instruments. The ASMAT results are compared to Ares I-X flight data.

  5. Reduced mobility but unaffected startle response in female rats exposed to prenatal dexamethasone: different sides to a phenotype.

    PubMed

    Kjaer, S L; Wegener, G; Rosenberg, R; Hougaard, K S

    2010-08-01

    An adverse fetal environment is strongly associated with behavioral and emotional development in later life, and environmental interactions with the genome are essential in the development of pathophysiology. This implicates that a genetic vulnerability or other predisposition may interact with the environment and stressful life events to trigger mental disease. The startle reflex is highly sensitive to fear and anxiety in humans and animals. Elevated startle magnitude has been proposed as a marker for neurodevelopmental disorders. We have recently established an animal model for possible development of anxiety, where female rats are exposed to two stressful life events, during prenatal life and as adolescents, respectively. A blood sampling procedure 3 months prior to startle testing has previously been found to increase basal startle, but only in prenatally stressed rats. As the experimental procedure of acoustic startle response (ASR) measurement resembles the aversive blood sampling procedure, this suggests that effects on ASR may be caused by aversive contextual similarities between blood sampling under restraint and the ASR test. In the present study, postnatal blood sampling was replaced by another dissimilar stressful event. Animals exposed to a high prenatal glucocorticoid level (i.e. 150 mug dexamethasone/kg) were statistically significantly more immobile in the forced swim test (FST) than animals exposed to a lower level of dexamethasone (50 mug/kg) and control animals. Exposure to a novel contextual stressor at 3 months of age (FST) was unassociated with changes in basal startle. These data suggest, since the high prenatal dexamethasone group showed increased immobility in the FST but coped equally well with controls in the ASR, that the outcome of environmental influences is determined by the individual circumstances as different situations require different coping abilities in the same individual.

  6. Fear conditioning facilitates rats gap detection measured by prepulse inhibition of the startle reflex

    NASA Astrophysics Data System (ADS)

    Zou, Dan; Wu, Xihong; Li, Liang

    2005-04-01

    A low-intensity acoustic event presented shortly before an intense startling sound can inhibit the acoustic startle reflex. This phenomenon is called prepulse inhibition (PPI), and is widely used as a model of sensorimotor gating in both humans and animals. Particularly, it has been used for evaluating the aging effect on the mouse's ability to detect a silent gap in otherwise continuous sounds. The present study extended this model to the emotional modulation of gap detection. The results show that a silent gap embedded in each of the two broadband noise sounds (55 dB SPL), which were delivered by two spatially separated loudspeakers, could inhibit the startle reflex that was induced by a loud sound presented from the third loudspeaker 50 ms after the gap. The inhibitory effect largely depended on the duration of the gap, with the mean duration threshold around 11 ms across 18 rats tested. Pairing the gap with foot shock in a temporally specific manner, but not in a temporally random manner, significantly reduced the duration threshold. Thus this study established a new animal behavioral model both for studying auditory temporal processing and for studying auditory signal-detection plasticity induced by emotional learning.

  7. Startle modulation during emotional anticipation and perception

    PubMed Central

    Sege, Christopher T.; Bradley, Margaret M.; Lang, Peter J.

    2014-01-01

    The startle reflex is potentiated when anticipating emotional, compared to neutral, pictures. This study investigated the time course of reflex modulation during anticipation and the impact of informative cuing on picture perception. Colors were used to signal the thematic content of emotional and neutral scenes; blink response modulation was measured by presenting acoustic startle probes 3, 2, or 1 second before picture onset or 2 seconds after picture onset. During anticipation of neutral scenes, blink magnitude showed increasing attenuation as picture onset approached, consistent with a modality-directed vigilance account. Conversely, when anticipating emotional scenes, reflex magnitude did not change over time, and blinks elicited closest to picture onset were potentiated compared to neutral. During perception, the expected reflex potentiation for unpleasant pictures was not found, suggesting that cuing may dampen defensive activation. PMID:24980898

  8. XV-15 Tiltrotor Aircraft: 1997 Acoustic Testing

    NASA Technical Reports Server (NTRS)

    Edwards, Bryan D.; Conner, David A.

    2003-01-01

    XV-15 acoustic test is discussed, and measured results are presented. The test was conducted by NASA Langley and Bell Helicopter Textron, Inc., during June - July 1997, at the BHTI test site near Waxahachie, Texas. This was the second in a series of three XV-15 tests to document the acoustic signature of the XV-15 tiltrotor aircraft for a variety of flight conditions and minimize the noise signature during approach. Tradeoffs between flight procedures and the measured noise are presented to illustrate the noise abatement flight procedures. The test objectives were to: (1) support operation of future tiltrotors by further developing and demonstrating low-noise flight profiles, while maintaining acceptable handling and ride qualities, and (2) refine approach profiles, selected from previous (1995) tiltrotor testing, to incorporate Instrument Flight Rules (IFR), handling qualities constraints, operations and tradeoffs with sound. Primary emphasis was given to the approach flight conditions where blade-vortex interaction (BVI) noise dominates, because this condition influences community noise impact more than any other. An understanding of this part of the noise generating process could guide the development of low noise flight operations and increase the tiltrotor's acceptance in the community.

  9. The Development of the Acoustic Design of NASA Glenn Research Center's New Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Mark E.; Hozman, Aron D.; McNelis, Anne M.

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is leading the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC s Plum Brook Station in Sandusky, Ohio. Benham Companies, LLC is currently constructing modal, base-shake sine and reverberant acoustic test facilities to support the future testing needs of NASA s space exploration program. The large Reverberant Acoustic Test Facility (RATF) will be approximately 101,000 ft3 in volume and capable of achieving an empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world s known active reverberant acoustic test facilities. The key to achieving the expected acoustic test spectra for a range of many NASA space flight environments in the RATF is the knowledge gained from a series of ground acoustic tests. Data was obtained from several NASA-sponsored test programs, including testing performed at the National Research Council of Canada s acoustic test facility in Ottawa, Ontario, Canada, and at the Redstone Technical Test Center acoustic test facility in Huntsville, Alabama. The majority of these tests were performed to characterize the acoustic performance of the modulators (noise generators) and representative horns that would be required to meet the desired spectra, as well as to evaluate possible supplemental gas jet noise sources. The knowledge obtained in each of these test programs enabled the design of the RATF sound generation system to confidently advance to its final acoustic design and subsequent on-going construction.

  10. The Development of the Acoustic Design of NASA Glenn Research Center's New Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Mark E.; Hozman, Aron D.; McNelis, Anne M.

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is leading the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC's Plum Brook Station in Sandusky, Ohio, USA. Benham Companies, LLC is currently constructing modal, base-shake sine and reverberant acoustic test facilities to support the future testing needs of NASA s space exploration program. The large Reverberant Acoustic Test Facility (RATF) will be approximately 101,000 ft3 in volume and capable of achieving an empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world s known active reverberant acoustic test facilities. The key to achieving the expected acoustic test spectra for a range of many NASA space flight environments in the RATF is the knowledge gained from a series of ground acoustic tests. Data was obtained from several NASA-sponsored test programs, including testing performed at the National Research Council of Canada s acoustic test facility in Ottawa, Ontario, Canada, and at the Redstone Technical Test Center acoustic test facility in Huntsville, Alabama, USA. The majority of these tests were performed to characterize the acoustic performance of the modulators (noise generators) and representative horns that would be required to meet the desired spectra, as well as to evaluate possible supplemental gas jet noise sources. The knowledge obtained in each of these test programs enabled the design of the RATF sound generation system to confidently advance to its final acoustic design and subsequent on-going construction.

  11. XV-15 Tiltrotor Aircraft: 1999 Acoustic Testing - Test Report

    NASA Technical Reports Server (NTRS)

    Edwards, Bryan D.; Conner, David A.

    2003-01-01

    An XV-15 acoustic test is discussed, and measured results are presented. The test was conducted by NASA Langley and Bell Helicopter Textron, Inc., during October 1999, at the BHTI test site near Waxahachie, Texas. As part of the NASA-sponsored Short Haul Civil Tiltrotor noise reduction initiative, this was the third in a series of three major XV-15 acoustic tests. Their purpose was to document the acoustic signature of the XV-15 tiltrotor aircraft for a variety of flight conditions and to minimize the noise signature during approach. Tradeoffs between flight procedures and the measured noise are presented to illustrate the noise abatement flight procedures. The test objectives were to support operation of future tiltrotors by further developing and demonstrating low-noise flight profiles, while maintaining acceptable handling and ride qualities, and refine approach profiles, selected from previous (1995 & 1997) tiltrotor testing, to incorporate Instrument Flight Rules (IFR), handling qualities constraints, operations and tradeoffs with sound. Primary emphasis was given to the approach flight conditions where blade-vortex interaction (BVI) noise dominates, because this condition influences community noise impact more than any other. An understanding of this part of the noise generating process could guide the development of low noise flight operations and increase the tiltrotor's acceptance in the community.

  12. Ares I Scale Model Acoustic Tests Instrumentation for Acoustic and Pressure Measurements

    NASA Technical Reports Server (NTRS)

    Vargas, Magda B.; Counter, Douglas D.

    2011-01-01

    The Ares I Scale Model Acoustic Test (ASMAT) was a development test performed at the Marshall Space Flight Center (MSFC) East Test Area (ETA) Test Stand 116. The test article included a 5% scale Ares I vehicle model and tower mounted on the Mobile Launcher. Acoustic and pressure data were measured by approximately 200 instruments located throughout the test article. There were four primary ASMAT instrument suites: ignition overpressure (IOP), lift-off acoustics (LOA), ground acoustics (GA), and spatial correlation (SC). Each instrumentation suite incorporated different sensor models which were selected based upon measurement requirements. These requirements included the type of measurement, exposure to the environment, instrumentation check-outs and data acquisition. The sensors were attached to the test article using different mounts and brackets dependent upon the location of the sensor. This presentation addresses the observed effect of the sensors and mounts on the acoustic and pressure measurements.

  13. The gap-startle paradigm to assess auditory temporal processing: Bridging animal and human research.

    PubMed

    Fournier, Philippe; Hébert, Sylvie

    2016-05-01

    The gap-prepulse inhibition of the acoustic startle (GPIAS) paradigm is the primary test used in animal research to identify gap detection thresholds and impairment. When a silent gap is presented shortly before a loud startling stimulus, the startle reflex is inhibited and the extent of inhibition is assumed to reflect detection. Here, we applied the same paradigm in humans. One hundred and fifty-seven normal-hearing participants were tested using one of five gap durations (5, 25, 50, 100, 200 ms) in one of the following two paradigms-gap-embedded in or gap-following-the continuous background noise. The duration-inhibition relationship was observable for both conditions but followed different patterns. In the gap-embedded paradigm, GPIAS increased significantly with gap duration up to 50 ms and then more slowly up to 200 ms (trend only). In contrast, in the gap-following paradigm, significant inhibition-different from 0--was observable only at gap durations from 50 to 200 ms. The finding that different patterns are found depending on gap position within the background noise is compatible with distinct mechanisms underlying each of the two paradigms.

  14. Tests Of Shear-Flow Model For Acoustic Impedance

    NASA Technical Reports Server (NTRS)

    Parrot, Tony L.; Watson, Willie R.; Jones, Michael G.

    1992-01-01

    Tests described in report conducted to validate two-dimensional shear-flow analytical model for determination of acoustic impedance of acoustic liner in grazing-incidence, grazing-flow environment by use of infinite-waveguide method. Tests successful for both upstream and downstream propagations. Work has potential for utility in testing of engine ducts in commercial aircraft.

  15. Acoustic emission monitoring of HFIR vessel during hydrostatic testing

    SciTech Connect

    Friesel, M.A.; Dawson, J.F.

    1992-08-01

    This report discusses the results and conclusions reached from applying acoustic emission monitoring to surveillance of the High Flux Isotope Reactor vessel during pressure testing. The objective of the monitoring was to detect crack growth and/or fluid leakage should it occur during the pressure test. The report addresses the approach, acoustic emission instrumentation, installation, calibration, and test results.

  16. Extreme startle and photomyoclonic response in severe hypocalcaemia.

    PubMed

    Moccia, Marcello; Erro, Roberto; Nicolella, Elvira; Striano, Pasquale; Striano, Salvatore

    2014-03-01

    We report the case of 62-year-old woman referred to our department because of a clinical suspicion of tonic-clonic seizures. Clinical examination revealed an exaggerated startle reflex, EEG showed a photomyoclonic response, and blood tests indicated severe hypocalcaemia. Additional clinical data, treatment strategies, and long-term follow-up visits were reported. The present report discusses the difficulties in distinguishing between epileptic and non-epileptic startles, and shows, for the first time, exaggerated startle reflex and extreme photomyoclonic response due to severe hypocalcaemia.

  17. Simultaneous EMG-fMRI during startle inhibition in monosymptomatic enuresis--an exploratory study.

    PubMed

    Schulz-Juergensen, Sebastian; Wunberg, David; Wolff, Stephan; Eggert, Paul; Siniatchkin, Michael

    2013-01-01

    Evidence is growing that monosymptomatic enuresis (ME) is a maturational disorder of the central nervous system with a lack of arousal and lacking inhibition of the micturition reflex. Previous studies have shown a significant reduction of prepulse inhibition (PPI) of startle in children with enuresis. However, it is still unclear whether the abnormal PPI in enuresis is based on an inhibitory deficit at brainstem or cortical level. Nine children with ME and ten healthy children were investigated using simultaneous recording of EMG from the M. orbicularis oculi and functional MRI. The experimental paradigm consisted of acoustic startle stimulation, with startle-alone stimuli and prepulse-startle combinations. Functional MRI data were processed using multiple regression and parametric modulation with startle amplitudes as a parameter. Neither patients with enuresis nor healthy children revealed measurable PPI in the MRI scanner. Startle stimuli caused equal hemodynamic changes in the acoustic cortex, medial prefrontal and orbitofrontal cortex in both groups. The amplitude of startle correlated with more prominent BOLD signal changes in the anterior cingulate cortex in healthy subjects than in patients with ME. This pronounced frontal activation in healthy controls was related to the PPI condition, indicating that the prefrontal cortex of healthy children was activated more strongly to inhibit startle than in patients with ME. In conclusion, apart from the possibility that recordings of PPI inside the MRI scanner may be compromised by methodological problems, the results of this study suggest that high cortical control mechanisms at the prefrontal level are relevant for the pathogenesis of ME.

  18. Magneto acoustic emission apparatus for testing materials for embrittlement

    NASA Technical Reports Server (NTRS)

    Allison, Sidney G. (Inventor); Min, Namkung (Inventor); Yost, William T. (Inventor); Cantrell, John H. (Inventor)

    1990-01-01

    A method and apparatus for testing steel components for temper embrittlement uses magneto-acoustic emission to nondestructively evaluate the component. Acoustic emission signals occur more frequently at higher levels in embrittled components. A pair of electromagnets are used to create magnetic induction in the test component. Magneto-acoustic emission signals may be generated by applying an ac current to the electromagnets. The acoustic emission signals are analyzed to provide a comparison between a component known to be unembrittled and a test component. Magnetic remanence is determined by applying a dc current to the electromagnets, then turning the magnets off and observing the residual magnetic induction.

  19. Role of bed nucleus of the stria terminalis and amygdala AMPA receptors in the development and expression of context conditioning and sensitization of startle by prior shock

    PubMed Central

    Davis, Michael

    2013-01-01

    A core symptom of post-traumatic stress disorder is hyper-arousal—manifest in part by increases in the amplitude of the acoustic startle reflex. Gewirtz et al. (Prog Neuropsychopharmacol Biol Psychiatry 22:625–648, 1998) found that, in rats, persistent shock-induced startle increases were prevented by pre-test electrolytic lesions of the bed nucleus of the stria terminalis (BNST). We used reversible inactivation to determine if similar effects reflect actions on (a) BNST neurons themselves versus fibers-of-passage, (b) the development versus expression of such increases, and (c) associative fear versus non-associative sensitization. Twenty-four hours after the last of three shock sessions, startle was markedly enhanced when rats were tested in a non-shock context. These increases decayed over the course of several days. Decay was unaffected by context exposure, and elevated startle was restored when rats were tested for the first time in the original shock context. Thus, both associative and non-associative components could be measured under different conditions. Pre-test intra-BNST infusions of the AMPA receptor antagonist NBQX (3 μg/side) blocked the non-associative (as did infusions into the basolateral amygdala) but not the associative component, whereas pre-shock infusions disrupted both. NBQX did not affect baseline startle or shock reactivity. These results indicate that AMPA receptors in or very near to the BNST are critical for the expression and development of non-associative shock-induced startle sensitization, and also for context fear conditioning, but not context fear expression. More generally, they suggest that treatments targeting the BNST may be clinically useful for treating trauma-related hyper-arousal and perhaps for retarding its development. PMID:23934654

  20. Acoustic Test Results of Melamine Foam with Application to Payload Fairing Acoustic Attenuation Systems

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Anne M.

    2014-01-01

    A spacecraft at launch is subjected to a harsh acoustic and vibration environment resulting from the passage of acoustic energy, created during the liftoff of a launch vehicle, through the vehicle's payload fairing. In order to ensure the mission success of the spacecraft it is often necessary to reduce the resulting internal acoustic sound pressure levels through the usage of acoustic attenuation systems. Melamine foam, lining the interior walls of the payload fairing, is often utilized as the main component of such a system. In order to better understand the acoustic properties of melamine foam, with the goal of developing improved acoustic attenuation systems, NASA has recently performed panel level testing on numerous configurations of melamine foam acoustic treatments at the Riverbank Acoustical Laboratory. Parameters assessed included the foam's thickness and density, as well as the effects of a top outer cover sheet material and mass barriers embedded within the foam. This testing followed the ASTM C423 standard for absorption and the ASTM E90 standard for transmission loss. The acoustic test data obtained and subsequent conclusions are the subjects of this paper.

  1. A New Acoustic Test Facility at Alcatel Space Test Centre

    NASA Astrophysics Data System (ADS)

    Meurat, A.; Jezequel, L.

    2004-08-01

    Due to the obsolescence of its acoustic test facility, Alcatel Space has initiated the investment of a large acoustic chamber on its test centre located in Cannes, south of France. This paper presents the main specification elaborated to design the facility, and the solution chosen : it will be located on a dedicated area of the existing test centre and will be based on technical solution already used in similar facilities over the world. The main structure consists in a chamber linked to an external envelope (concrete building) through suspension aiming at decoupling the vibration and preventing from seismic risks. The noise generation system is based on the use of Wyle modulators located on the chamber roof. Gaseous nitrogen is produced by a dedicated gas generator developed by Air-Liquide that could deliver high flow rate with accurate pressure and temperature controls. The control and acquisition system is based on existing solution implemented on the vibration facilities of the test centre. With the start of the construction in May 2004, the final acceptance tests are planned for April 2005, and the first satellites to be tested are planned for May 2005.

  2. Differential Neural Responses Underlying the Inhibition of the Startle Response by Pre-Pulses or Gaps in Mice

    PubMed Central

    Moreno-Paublete, Rocio; Canlon, Barbara; Cederroth, Christopher R.

    2017-01-01

    Gap pre-pulse inhibition of the acoustic startle (GPIAS) is a behavioral paradigm used for inferring the presence of tinnitus in animal models as well as humans. In contrast to pre-pulse inhibition (PPI), the neural circuitry controlling GPIAS is poorly understood. To increase our knowledge on GPIAS, a comparative study with PPI was performed in mice combining these behavioral tests and c-Fos activity mapping in brain areas involved in the inhibition of the acoustic startle reflex (ASR). Both pre-pulses and gaps efficiently inhibited the ASR and abolished the induction of c-Fos in the pontine reticular nucleus. Differential c-Fos activation was found between PPI and GPIAS in the forebrain whereby PPI activated the lateral globus pallidus and GPIAS activated the primary auditory cortex. Thus, different neural maps are regulating the inhibition of the startle response by pre-pulses or gaps. To further investigate this differential response to PPI and GPIAS, we pharmacologically disrupted PPI and GPIAS with D-amphetamine or Dizocilpine (MK-801) to target dopamine efflux and to block NMDA receptors, respectively. Both D-amp and MK-801 efficiently decreased PPI and GPIAS. We administered Baclofen, an agonist GABAB receptor, but failed to detect any robust rescue of the effects of D-amp and MK-801 suggesting that PPI and GPIAS are GABAB-independent. These novel findings demonstrate that the inhibition of the ASR by pre-pulses or gaps is orchestrated by different neural pathways. PMID:28239338

  3. Differential Neural Responses Underlying the Inhibition of the Startle Response by Pre-Pulses or Gaps in Mice.

    PubMed

    Moreno-Paublete, Rocio; Canlon, Barbara; Cederroth, Christopher R

    2017-01-01

    Gap pre-pulse inhibition of the acoustic startle (GPIAS) is a behavioral paradigm used for inferring the presence of tinnitus in animal models as well as humans. In contrast to pre-pulse inhibition (PPI), the neural circuitry controlling GPIAS is poorly understood. To increase our knowledge on GPIAS, a comparative study with PPI was performed in mice combining these behavioral tests and c-Fos activity mapping in brain areas involved in the inhibition of the acoustic startle reflex (ASR). Both pre-pulses and gaps efficiently inhibited the ASR and abolished the induction of c-Fos in the pontine reticular nucleus. Differential c-Fos activation was found between PPI and GPIAS in the forebrain whereby PPI activated the lateral globus pallidus and GPIAS activated the primary auditory cortex. Thus, different neural maps are regulating the inhibition of the startle response by pre-pulses or gaps. To further investigate this differential response to PPI and GPIAS, we pharmacologically disrupted PPI and GPIAS with D-amphetamine or Dizocilpine (MK-801) to target dopamine efflux and to block NMDA receptors, respectively. Both D-amp and MK-801 efficiently decreased PPI and GPIAS. We administered Baclofen, an agonist GABAB receptor, but failed to detect any robust rescue of the effects of D-amp and MK-801 suggesting that PPI and GPIAS are GABAB-independent. These novel findings demonstrate that the inhibition of the ASR by pre-pulses or gaps is orchestrated by different neural pathways.

  4. Modality-specific attention under imminent but not remote threat of shock: evidence from differential prepulse inhibition of startle.

    PubMed

    Cornwell, Brian R; Echiverri, Aileen M; Covington, Matthew F; Grillon, Christian

    2008-06-01

    Theories of animal defensive behavior postulate that imminent, predictable threat elicits highly focused attention toward the threat source, whereas remote, unpredictable threat elicits distributed attention to the overall environment. We used threat of shock combined with measurement of prepulse inhibition of the startle reflex to test these claims in humans. Twenty-seven participants experienced periods of threat and safety. Threat and safe periods were short or long, with the short threat periods conveying relatively predictable, imminent shocks and the long threat periods conveying unpredictable shocks. Startle reflexes were elicited with equal numbers of acoustic probes presented alone, preceded by a tactile prepulse, or preceded by an auditory prepulse. We observed enhanced tactile relative to auditory prepulse inhibition during short threat periods only. This finding supports the notion that imminent threat, but not remote threat, elicits attention focused toward the relevant modality, potentially reflecting preparatory activity to minimize the impact of the noxious stimulus.

  5. Digital control of high-intensity acoustic testing

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1975-01-01

    To eliminate previous system instabilities and control high-intensity acoustic tests, a digital control vibration test system is modified by a software change. Three systems for the control of acoustic testing are compared: a hybrid digital/analog system, a digital vibration system, and the same digital vibration system modified by a software change to allow acoustic testing. It is shown that the hybrid system and the modified vibration system exhibit almost equal performance, although the hybrid system performs testing twice as fast. The development of a specialized acoustic test control system is justified since it costs far less than the general-purpose vibration control system. However, the latter is much easier to set up for a test, which is important in preventing overtesting of valuable spacecraft components.

  6. Acoustic guide for noise-transmission testing of aircraft

    NASA Technical Reports Server (NTRS)

    Vaicaitis, Rimas (Inventor)

    1987-01-01

    Selective testing of aircraft or other vehicular components without requiring disassembly of the vehicle or components was accomplished by using a portable guide apparatus. The device consists of a broadband noise source, a guide to direct the acoustic energy, soft sealing insulation to seal the guide to the noise source and to the vehicle component, and noise measurement microphones, both outside the vehicle at the acoustic guide output and inside the vehicle to receive attenuated sound. By directing acoustic energy only to selected components of a vehicle via the acoustic guide, it is possible to test a specific component, such as a door or window, without picking up extraneous noise which may be transmitted to the vehicle interior through other components or structure. This effect is achieved because no acoustic energy strikes the vehicle exterior except at the selected component. Also, since the test component remains attached to the vehicle, component dynamics with vehicle frame are not altered.

  7. 21 CFR 874.1060 - Acoustic chamber for audiometric testing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Acoustic chamber for audiometric testing. 874.1060 Section 874.1060 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Diagnostic Devices § 874.1060 Acoustic chamber...

  8. 21 CFR 874.1060 - Acoustic chamber for audiometric testing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Acoustic chamber for audiometric testing. 874.1060 Section 874.1060 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Diagnostic Devices § 874.1060 Acoustic chamber...

  9. 21 CFR 874.1060 - Acoustic chamber for audiometric testing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Acoustic chamber for audiometric testing. 874.1060 Section 874.1060 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Diagnostic Devices § 874.1060 Acoustic chamber...

  10. Ares I Scale Model Acoustic Test Instrumentation for Acoustic and Pressure Measurements

    NASA Technical Reports Server (NTRS)

    Vargas, Magda B.; Counter, Douglas

    2011-01-01

    Ares I Scale Model Acoustic Test (ASMAT) is a 5% scale model test of the Ares I vehicle, launch pad and support structures conducted at MSFC to verify acoustic and ignition environments and evaluate water suppression systems Test design considerations 5% measurements must be scaled to full scale requiring high frequency measurements Users had different frequencies of interest Acoustics: 200 - 2,000 Hz full scale equals 4,000 - 40,000 Hz model scale Ignition Transient: 0 - 100 Hz full scale equals 0 - 2,000 Hz model scale Environment exposure Weather exposure: heat, humidity, thunderstorms, rain, cold and snow Test environments: Plume impingement heat and pressure, and water deluge impingement Several types of sensors were used to measure the environments Different instrument mounts were used according to the location and exposure to the environment This presentation addresses the observed effects of the selected sensors and mount design on the acoustic and pressure measurements

  11. Acoustic tests of augmentor wing model

    NASA Technical Reports Server (NTRS)

    Goodykoontz, J. H.

    1977-01-01

    Acoustic and aerodynamic data were obtained for a full-scale section of an augmentor wing. Features of the design included a single-row, multielement nozzle array and acoustically tuned panels placed on the interior surfaces of the augmentor. When the data were extrapolated to a 91,000-kilogram aircraft, the calculated sideline perceived noise levels were approximately the same for either the takeoff or approach condition.

  12. Acoustic emission from composite materials. [nondestructive tests

    NASA Technical Reports Server (NTRS)

    Visconti, I. C.; Teti, R.

    1979-01-01

    The two basic areas where the acoustic emission (AE) technique can be applied are materials research and the evaluation of structural reliability. This experimental method leads to a better understanding of fracture mechanisms and is an NDT technique particularly well suited for the study of propagating cracks. Experiments are described in which acoustic emissions were unambiguously correlated with microstructural fracture mechanisms. The advantages and limitations of the AE technique are noted.

  13. Drive Rig Mufflers for Model Scale Engine Acoustic Testing

    NASA Technical Reports Server (NTRS)

    Stephens, David

    2010-01-01

    Testing of air breathing propulsion systems in the 9x15 foot wind tunnel at NASA Glenn Research Center depends on compressed air turbines for power. The drive rig turbines exhaust directly to the wind tunnel test section, and have been found to produce significant unwanted noise that reduces the quality of the acoustic measurements of the model being tested. In order to mitigate this acoustic contamination, a muffler can be attached downstream of the drive rig turbine. The modern engine designs currently being tested produce much less noise than traditional engines, and consequently a lower noise floor is required of the facility. An acoustic test of a muffler designed to mitigate this extraneous noise is presented, and a noise reduction of 8 dB between 700 Hz and 20 kHz was documented, significantly improving the quality of acoustic measurements in the facility.

  14. High-temperature acoustic test facilities and methods

    NASA Astrophysics Data System (ADS)

    Pearson, Jerome

    1994-09-01

    The Wright Laboratory is the Air Force center for air vehicles, responsible for developing advanced technology and incorporating it into new flight vehicles and for continuous technological improvement of operational air vehicles. Part of that responsibility is the problem of acoustic fatigue. With the advent of jet aircraft in the 1950's, acoustic fatigue of aircraft structure became a significant problem. In the 1960's the Wright Laboratory constructed the first large acoustic fatigue test facilities in the United States, and the laboratory has been a dominant factor in high-intensity acoustic testing since that time. This paper discusses some of the intense environments encountered by new and planned Air Force flight vehicles, and describes three new acoustic test facilities of the Wright Laboratory designed for testing structures in these dynamic environments. These new test facilities represent the state of the art in high-temperature, high-intensity acoustic testing and random fatigue testing. They will allow the laboratory scientists and engineers to test the new structures and materials required to withstand the severe environments of captive-carry missiles, augmented lift wings and flaps, exhaust structures of stealth aircraft, and hypersonic vehicle structures well into the twenty-first century.

  15. Issues Related to Large Flight Hardware Acoustic Qualification Testing

    NASA Technical Reports Server (NTRS)

    Kolaini, Ali R.; Perry, Douglas C.; Kern, Dennis L.

    2011-01-01

    The characteristics of acoustical testing volumes generated by reverberant chambers or a circle of loudspeakers with and without large flight hardware within the testing volume are significantly different. The parameters attributing to these differences are normally not accounted for through analysis or acoustic tests prior to the qualification testing without the test hardware present. In most cases the control microphones are kept at least 2-ft away from hardware surfaces, chamber walls, and speaker surfaces to minimize the impact of the hardware in controlling the sound field. However, the acoustic absorption and radiation of sound by hardware surfaces may significantly alter the sound pressure field controlled within the chamber/speaker volume to a given specification. These parameters often result in an acoustic field that may provide under/over testing scenarios for flight hardware. In this paper the acoustic absorption by hardware surfaces will be discussed in some detail. A simple model is provided to account for some of the observations made from Mars Science Laboratory spacecraft that recently underwent acoustic qualification tests in a reverberant chamber.

  16. Prediction and Perception: Defensive Startle Modulation

    PubMed Central

    Sege, Christopher T.; Bradley, Margaret M.; Lang, Peter J.

    2015-01-01

    Previous research indicates that predictive cues can dampen subsequent defensive reactions. The present study investigated whether effects of cuing are specific to aversive stimuli, using modulation of the blink startle reflex as a measure of emotional reactivity. Participants viewed pictures depicting violence, romance/ erotica, or mundane content. On half of all trials, a cue (color) predicted the content of the upcoming picture; on the remaining trials, scenes were presented without a cue. Acoustic startle probes were presented during picture viewing on trials with predictive cues and trials without a cue. Replicating previous studies, blink reflexes elicited when viewing violent pictures that had not been preceded by a cue were potentiated compared to un-cued mundane scenes, and reflexes were attenuated when viewing scenes of erotica/ romance that had not been cued. On the other hand, reflex potentiation when viewing scenes of violence (relative to mundane scenes) was eliminated when these pictures were preceded by a predictive cue, whereas scenes of romance prompted reliable reflex attenuation regardless of whether pictures were cued or not. Taken together, the data suggest that cuing elicits an anticipatory coping process that is specific to aversive stimuli. PMID:26399464

  17. Fractionation of muscle activity in rapid responses to startling cues

    PubMed Central

    Dean, Lauren R.

    2017-01-01

    Movements in response to acoustically startling cues have shorter reaction times than those following less intense sounds; this is known as the StartReact effect. The neural underpinnings for StartReact are unclear. One possibility is that startling cues preferentially invoke the reticulospinal tract to convey motor commands to spinal motoneurons. Reticulospinal outputs are highly divergent, controlling large groups of muscles in synergistic patterns. By contrast the dominant pathway in primate voluntary movement is the corticospinal tract, which can access small groups of muscles selectively. We therefore hypothesized that StartReact responses would be less fractionated than standard voluntary reactions. Electromyogram recordings were made from 15 muscles in 10 healthy human subjects as they carried out 32 varied movements with the right forelimb in response to startling and nonstartling auditory cues. Movements were chosen to elicit a wide range of muscle activations. Multidimensional muscle activity patterns were calculated at delays from 0 to 100 ms after the onset of muscle activity and subjected to principal component analysis to assess fractionation. In all cases, a similar proportion of the total variance could be explained by a reduced number of principal components for the startling and the nonstartling cue. Muscle activity patterns for a given task were very similar in response to startling and nonstartling cues. This suggests that movements produced in the StartReact paradigm rely on similar contributions from different descending pathways as those following voluntary responses to nonstartling cues. NEW & NOTEWORTHY We demonstrate that the ability to activate muscles selectively is preserved during the very rapid reactions produced following a startling cue. This suggests that the contributions from different descending pathways are comparable between these rapid reactions and more typical voluntary movements. PMID:28003416

  18. Acoustical Analysis of a Test Horn.

    DTIC Science & Technology

    1988-01-20

    Laboratories, Inc. if /pliable) Flight Dynamics Laboratory (AFWAL/ FIBRA ) n/a Air Force Wright Aeronautical Laboratories 6c. ADDRESS (City, State, and ZIPCode) 7b...AFWAL/ FIBRA DO Form 1473, JUN 86 Previous editions are obsolete. SECURITY CLASSIFICATION OF THIS PAGE UNCLASSIFIED "S.,, PREFACE This acoustical

  19. Acoustic emissions verification testing of International Space Station experiment racks at the NASA Glenn Research Center Acoustical Testing Laboratory

    NASA Astrophysics Data System (ADS)

    Akers, James C.; Passe, Paul J.; Cooper, Beth A.

    2005-09-01

    The Acoustical Testing Laboratory (ATL) at the NASA John H. Glenn Research Center (GRC) in Cleveland, OH, provides acoustic emission testing and noise control engineering services for a variety of specialized customers, particularly developers of equipment and science experiments manifested for NASA's manned space missions. The ATL's primary customer has been the Fluids and Combustion Facility (FCF), a multirack microgravity research facility being developed at GRC for the USA Laboratory Module of the International Space Station (ISS). Since opening in September 2000, ATL has conducted acoustic emission testing of components, subassemblies, and partially populated FCF engineering model racks. The culmination of this effort has been the acoustic emission verification tests on the FCF Combustion Integrated Rack (CIR) and Fluids Integrated Rack (FIR), employing a procedure that incorporates ISO 11201 (``Acoustics-Noise emitted by machinery and equipment-Measurement of emission sound pressure levels at a work station and at other specified positions-Engineering method in an essentially free field over a reflecting plane''). This paper will provide an overview of the test methodology, software, and hardware developed to perform the acoustic emission verification tests on the CIR and FIR flight racks and lessons learned from these tests.

  20. Space Launch System Scale Model Acoustic Test Ignition Overpressure Testing

    NASA Technical Reports Server (NTRS)

    Nance, Donald K.; Liever, Peter A.

    2015-01-01

    The overpressure phenomenon is a transient fluid dynamic event occurring during rocket propulsion system ignition. This phenomenon results from fluid compression of the accelerating plume gas, subsequent rarefaction, and subsequent propagation from the exhaust trench and duct holes. The high-amplitude unsteady fluid-dynamic perturbations can adversely affect the vehicle and surrounding structure. Commonly known as ignition overpressure (IOP), this is an important design-to environment for the Space Launch System (SLS) that NASA is currently developing. Subscale testing is useful in validating and verifying the IOP environment. This was one of the objectives of the Scale Model Acoustic Test (SMAT), conducted at Marshall Space Flight Center (MSFC). The test data quantifies the effectiveness of the SLS IOP suppression system and improves the analytical models used to predict the SLS IOP environments. The reduction and analysis of the data gathered during the SMAT IOP test series requires identification and characterization of multiple dynamic events and scaling of the event waveforms to provide the most accurate comparisons to determine the effectiveness of the IOP suppression systems. The identification and characterization of the overpressure events, the waveform scaling, the computation of the IOP suppression system knockdown factors, and preliminary comparisons to the analytical models are discussed.

  1. Space Launch System Scale Model Acoustic Test Ignition Overpressure Testing

    NASA Technical Reports Server (NTRS)

    Nance, Donald; Liever, Peter; Nielsen, Tanner

    2015-01-01

    The overpressure phenomenon is a transient fluid dynamic event occurring during rocket propulsion system ignition. This phenomenon results from fluid compression of the accelerating plume gas, subsequent rarefaction, and subsequent propagation from the exhaust trench and duct holes. The high-amplitude unsteady fluid-dynamic perturbations can adversely affect the vehicle and surrounding structure. Commonly known as ignition overpressure (IOP), this is an important design-to environment for the Space Launch System (SLS) that NASA is currently developing. Subscale testing is useful in validating and verifying the IOP environment. This was one of the objectives of the Scale Model Acoustic Test, conducted at Marshall Space Flight Center. The test data quantifies the effectiveness of the SLS IOP suppression system and improves the analytical models used to predict the SLS IOP environments. The reduction and analysis of the data gathered during the SMAT IOP test series requires identification and characterization of multiple dynamic events and scaling of the event waveforms to provide the most accurate comparisons to determine the effectiveness of the IOP suppression systems. The identification and characterization of the overpressure events, the waveform scaling, the computation of the IOP suppression system knockdown factors, and preliminary comparisons to the analytical models are discussed.

  2. Cassini/Titan-4 Acoustic Blanket Development and Testing

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Anne M.

    1996-01-01

    NASA Lewis Research Center recently led a multi-organizational effort to develop and test verify new acoustic blankets. These blankets support NASA's goal in reducing the Titan-4 payload fairing internal acoustic environment to allowable levels for the Cassini spacecraft. To accomplish this goal a two phase acoustic test program was utilized. Phase One consisted of testing numerous blanket designs in a flat panel configuration. Phase Two consisted of testing the most promising designs out of Phase One in a full scale cylindrical payload fairing. This paper will summarize this highly successful test program by providing the rationale and results for each test phase, the impacts of this testing on the Cassini mission, as well as providing some general information on blanket designs.

  3. Maneuver Acoustic Flight Test of the Bell 430 Helicopter

    NASA Technical Reports Server (NTRS)

    Watts, Michael E.; Snider, Royce; Greenwood, Eric; Baden, Joel

    2012-01-01

    A cooperative flight test by NASA, Bell Helicopter and the U.S. Army to characterize the steady state acoustics and measure the maneuver noise of a Bell Helicopter 430 aircraft was accomplished. The test occurred during June/July, 2011 at Eglin Air Force Base, Florida. This test gathered a total of 410 data points over 10 test days and compiled an extensive data base of dynamic maneuver measurements. Three microphone configurations with up to 31 microphones in each configuration were used to acquire acoustic data. Aircraft data included DGPS, aircraft state and rotor state information. This paper provides an overview of the test.

  4. Acoustic test and analyses of three advanced turboprop models

    NASA Technical Reports Server (NTRS)

    Brooks, B. M.; Metzger, F. B.

    1980-01-01

    Results of acoustic tests of three 62.2 cm (24.5 inch) diameter models of the prop-fan (a small diameter, highly loaded. Multi-bladed variable pitch advanced turboprop) are presented. Results show that there is little difference in the noise produced by unswept and slightly swept designs. However, the model designed for noise reduction produces substantially less noise at test conditions simulating 0.8 Mach number cruise speed or at conditions simulating takeoff and landing. In the near field at cruise conditions the acoustically designed. In the far field at takeoff and landing conditions the acoustically designed model is 5 db quieter than unswept or slightly swept designs. Correlation between noise measurement and theoretical predictions as well as comparisons between measured and predicted acoustic pressure pulses generated by the prop-fan blades are discussed. The general characteristics of the pulses are predicted. Shadowgraph measurements were obtained which showed the location of bow and trailing waves.

  5. Tabulation of data from the tip aerodynamics and acoustics test

    NASA Technical Reports Server (NTRS)

    Cross, Jeffrey L.; Tu, Wilson

    1990-01-01

    In a continuing effort to understand helicopter rotor tip aerodynamics and acoustics, researchers at Ames Research Center conducted a flight test. The test was performed using the NASA White Cobra and a set of highly instrumented blades. Tabular and graphic summaries of two data subsets from the Tip Aerodynamics and Acoustics Test are given. The data presented are for airloads, blade structural loads, blade vibrations, with summary tables of the aircraft states for each test point. The tabular data consist of the first 15 harmonics only, whereas the plots contain the entire measured frequency content.

  6. Effects of a startle stimulus on response speed and inhibition in a go/no-go task.

    PubMed

    Washington, Jessica R; Blumenthal, Terry D

    2015-06-01

    Two studies examined the interaction of an acoustic startle stimulus and visual go/no-go task stimuli on startle reactivity and task performance. In the first study, an acoustic stimulus (50 ms, 100 dB noise) was presented alone or with a green (go) or red (no-go) circle; in the second study, a prepulse (50 ms, 75 dB noise) was presented alone or 120 ms before the startle stimulus or circle. The startle stimulus speeded responses to the go stimuli and increased the covert false alarm rate in the no-go condition (measured by EMG activity in the hand), although very few overt errors were made in the no-go condition. Startle response magnitude was increased by a circle but decreased by a prepulse. The speeding of go responses caused by a startle stimulus was attenuated by the occurrence of a startle response, suggesting that an intense accessory stimulus can facilitate responding to an imperative stimulus, and that the startle response to that intense stimulus can interfere with that facilitation.

  7. In-flight acoustic testing techniques using the YO-3A Acoustic Research Aircraft

    NASA Technical Reports Server (NTRS)

    Cross, J. L.; Watts, M. E.

    1984-01-01

    This report discusses the flight testing techniques and equipment employed during air-to-air acoustic testing of helicopters at Ames Research Center. The in flight measurement technique used enables acoustic data to be obtained without the limitations of anechoic chambers or the multitude of variables encountered in ground based flyover testing. The air-to-air testing is made possible by the NASA YO-3A Acoustic Research Aircraft. This "Quiet Aircraft' is an acoustically instrumented version of a quiet observation aircraft manufactured for the military. To date, tests with the following aircraft have been conducted: YO-3A background noise; Hughes 500D; Hughes AH-64; Bell AH-1S; Bell AH-1G. Several system upgrades are being designed and implemented to improve the quality of data. This report will discuss not only the equipment involved and aircraft tested, but also the techniques used in these tests. In particular, formation flying position locations, and the test matrices will be discussed. Examples of data taken will also be presented.

  8. In-flight acoustic testing techniques using the YO-3A acoustic research aircraft

    NASA Technical Reports Server (NTRS)

    Cross, J. L.; Watts, M. E.

    1983-01-01

    This report discusses the flight testing techniques and equipment employed during air-to-air acoustic testing of helicopters at Ames Research Center. The in-flight measurement technique used enables acoustic data to be obtained without the limitations of anechoic chambers or the multitude of variables encountered in ground based flyover testing. The air-to-air testing is made possible by the NASA YO-3A Acoustic Research Aircraft. This 'Quiet Aircraft' is an acoustically instrumented version of a quiet observation aircraft manufactured for the military. To date, tests with the following aircraft have been conducted: YO-3A background noise; Hughes 500D; Hughes AH-64; Bell AH-1S; Bell AH-1G. Several system upgrades are being designed and implemented to improve the quality of data. This report will discuss not only the equipment involved and aircraft tested, but also the techniques used in these tests. In particular, formation flying, position locations, and the test matrices will be discussed. Examples of data taken will also be presented.

  9. The Testing Behind The Test Facility: The Acoustic Design of the NASA Glenn Research Center's World-Class Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Mark E.; McNelis, Anne M.

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is leading the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC?s Plum Brook Station in Sandusky, Ohio, USA. Benham Companies, LLC is currently constructing modal, base-shake sine and reverberant acoustic test facilities to support the future testing needs of NASA?s space exploration program. T he large Reverberant Acoustic Test Facility (RATF) will be approximately 101,000 ft3 in volume and capable of achieving an empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world?s known active reverberant acoustic test facilities. The key to achieving the expected acoustic test spectra for a range of many NASA space flight environments in the RATF is the knowledge gained from a series of ground acoustic tests. Data was obtained from several NASA-sponsored test programs, including testing performed at the National Research Council of Canada?s acoustic test facility in Ottawa, Ontario, Canada, and at the Redstone Technical Test Center acoustic test facility in Huntsville, Alabama, USA. The majority of these tests were performed to characterize the acoustic performance of the modulators (noise generators) and representative horns that would be required to meet the desired spectra, as well as to evaluate possible supplemental gas jet noise sources. The knowledge obtained in each of these test programs enabled the design of the RATF sound generation system to confidently advance to its final acoustic de-sign and subsequent on-going construction.

  10. The Testing Behind the Test Facility: the Acoustic Design of the NASA Glenn Research Center's World-Class Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; McNelis, Mark E.; Hozman, Aron D.; McNelis, Anne M.

    2010-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is leading the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC s Plum Brook Station in Sandusky, Ohio, U.S.A. Benham Companies, LLC is currently constructing modal, base-shake sine and reverberant acoustic test facilities to support the future testing needs of NASA s space exploration program. The large Reverberant Acoustic Test Facility (RATF) will be approximately 101,000 ft3 in volume and capable of achieving an empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world s known active reverberant acoustic test facilities. The key to achieving the expected acoustic test spectra for a range of many NASA space flight environments in the RATF is the knowledge gained from a series of ground acoustic tests. Data was obtained from several NASA-sponsored test programs, including testing performed at the National Research Council of Canada s acoustic test facility in Ottawa, Ontario, Canada, and at the Redstone Technical Test Center acoustic test facility in Huntsville, Alabama, U.S.A. The majority of these tests were performed to characterize the acoustic performance of the modulators (noise generators) and representative horns that would be required to meet the desired spectra, as well as to evaluate possible supplemental gas jet noise sources. The knowledge obtained in each of these test programs enabled the design of the RATF sound generation system to confidently advance to its final acoustic design and subsequent ongoing construction.

  11. The Testing Behind The Test Facility: The Acoustic Design of the NASA Glenn Research Center's World-Class Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Hozman, Aron D.; Hughes, William O.; McNelis, Mark E.; McNelis, Anne M.

    2011-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is leading the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC's Plum Brook Station in Sandusky, Ohio, USA. Benham Companies, LLC is currently constructing modal, base-shake sine and reverberant acoustic test facilities to support the future testing needs of NASA's space exploration program. The large Reverberant Acoustic Test Facility (RATF) will be approximately 101,000 cu ft in volume and capable of achieving an empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world's known active reverberant acoustic test facilities. The key to achieving the expected acoustic test spectra for a range of many NASA space flight environments in the RATF is the knowledge gained from a series of ground acoustic tests. Data was obtained from several NASA-sponsored test programs, including testing performed at the National Research Council of Canada's acoustic test facility in Ottawa, Ontario, Canada, and at the Redstone Technical Test Center acoustic test facility in Huntsville, Alabama, USA. The majority of these tests were performed to characterize the acoustic performance of the modulators (noise generators) and representative horns that would be required to meet the desired spectra, as well as to evaluate possible supplemental gas jet noise sources. The knowledge obtained in each of these test programs enabled the design of the RATF sound generation system to confidently advance to its final acoustic design and subsequent on-going construction.

  12. Airpuff startle probes: an efficacious and less aversive alternative to white-noise.

    PubMed

    Lissek, Shmuel; Baas, Johanna M P; Pine, Daniel S; Orme, Kaebah; Dvir, Sharone; Nugent, Monique; Rosenberger, Emily; Rawson, Elizabeth; Grillon, Christian

    2005-03-01

    Fear-potentiated startle (FPS) is an increasingly popular psychophysiological method for the objective assessment of fear and anxiety. Studies applying this method often elicit the startle reflex with loud white-noise stimuli. Such intense stimuli may, however, alter psychological processes of interest by creating unintended emotional or attentional artifacts. Additionally, loud acoustic probes may be unsuitable for use with infants, children, the elderly, and those with hearing damage. Past studies have noted robust and reliable startle reflexes elicited by low intensity airpuffs. The current study compares the aversiveness of white-noise (102 dB) and airpuff (3 psi) probes and examines the sensitivity of each probe for the assessment of fear-potentiated startle. Results point to less physiological arousal and self-reported reactivity to airpuff versus white-noise probes. Additionally, both probes elicited equal startle magnitudes, response probabilities, and levels of fear-potentiated startle. Such results support the use of low intensity airpuffs as efficacious and relatively non-aversive startle probes.

  13. Effect of stress and attention on startle response and prepulse inhibition.

    PubMed

    De la Casa, Luis Gonzalo; Mena, Auxiliadora; Ruiz-Salas, Juan Carlos

    2016-10-15

    The startle reflex magnitude can be modulated when a weak stimulus is presented before the onset of the startle stimulus, a phenomenon termed prepulse inhibition (PPI). Previous research has demonstrated that emotional processes can modulate PPI and startle intensity, but the available evidence is inconclusive. In order to obtain additional evidence in this domain, we conducted two experiments intended to analyze the effect of induced stress and attentional load on PPI and startle magnitude. Specifically, in Experiment 1 we used a between subject strategy to evaluate the effect on startle response and PPI magnitude of performing a difficult task intended to induce stress in the participants, as compared to a group exposed to a control task. In Experiment 2 we evaluated the effect of diverting attention from the acoustic stimulus on startle and PPI intensity. The results seem to indicate that induced stress can reduce PPI, and that startle reflex intensity is reduced when attention is directed away from the auditory stimulus that induces the reflex.

  14. Acupuncture Affects Autonomic and Endocrine but Not Behavioural Responses Induced by Startle in Horses

    PubMed Central

    Villas-Boas, Julia Dias; Dias, Daniel Penteado Martins; Trigo, Pablo Ignacio; Almeida, Norma Aparecida dos Santos; de Almeida, Fernando Queiroz; de Medeiros, Magda Alves

    2015-01-01

    Startle is a fast response elicited by sudden acoustic, tactile, or visual stimuli in a variety of animals and in humans. As the magnitude of startle response can be modulated by external and internal variables, it can be a useful tool to study reaction to stress. Our study evaluated whether acupuncture can change cardiac autonomic modulation (heart rate variability); and behavioural (reactivity) and endocrine (cortisol levels) parameters in response to startle. Brazilian Sport horses (n = 6) were subjected to a model of startle in which an umbrella was abruptly opened near the horse. Before startle, the horses were subjected to a 20-minute session of acupuncture in acupoints GV1, HT7, GV20, and BL52 (ACUP) and in nonpoints (NP) or left undisturbed (CTL). For analysis of the heart rate variability, ultrashort-term (64 s) heart rate series were interpolated (4 Hz) and divided into 256-point segments and the spectra integrated into low (LF; 0.01–0.07 Hz; index of sympathetic modulation) and high (HF; 0.07–0.50 Hz; index of parasympathetic modulation) frequency bands. Acupuncture (ACUP) changed the sympathovagal balance with a shift towards parasympathetic modulation, reducing the prompt startle-induced increase in LF/HF and reducing cortisol levels 30 min after startle. However, acupuncture elicited no changes in behavioural parameters. PMID:26413116

  15. Comparison of Two High Intensity Acoustic Test Facilities

    NASA Astrophysics Data System (ADS)

    Launay, A.; Tadao Sakita, M.; Kim, Youngkey K.

    2004-08-01

    In two different countries, at the same period of time, the institutes in charge of the development of space activities have decided to extend their satellite integration and test center, and to implement a reverberant acoustic chamber. In Brazil the INPE laboratory (LIT : Laboratorio de Integracao e Testes) and in South Korea the KARI laboratory (SITC : Satellite Integration and Test Center) started their projects in July 2000 for the RATF (Reverberant Acoustic Test Facility) and in May 2001 for the HIAC (High Intensity Acoustic Chamber) respectively, writing the technical specifications. The kick-off meetings took place in December 2000 and in February 2002 and the opening ceremonies in December 19, 2002 in Brazil and in August 22, 2003 in Korea. This paper compares the two projects in terms of design choices, manufacturing processes, equipment installed and technical final characteristics.

  16. Digital control of high-intensity acoustic testing

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1975-01-01

    A high intensity acoustic test system is reported that consists of a reverberation room measuring 18 feet wide by 21 feet long by 26 feet high, with an internal volume of 10,900 cubic feet. The room is rectangular in shape. Acoustic energy is supplied through two 50-Hz cutoff exponential horns about 12 feet long. Each of the two horns has two transducers rated at 4000 acoustic watts each. A gaseous nitrogen supply is used to supply the energy. The equalized electrical signal is corrected by a circuit designed to compensate for the transducer nonlinearity, then fed into one channel of a phase linear power amplifier, then into the transducer. The amplifiers have been modified to increase their reliability. The acoustic energy in the room is monitored by six B and K 1/2-inch condenser microphones. The electrical signal from each microphone is fed into a six channel real time averager to give a spatial average of the signals.

  17. Sandia National Laboratories' new high level acoustic test facility

    SciTech Connect

    Rogers, J. D.; Hendrick, D. M.

    1989-01-01

    A high intensity acoustic test facility has been designed and is under construction at Sandia National Laboratories in Albuquerque, NM. The chamber is designed to provide an acoustic environment of 154dB (re 20 {mu}Pa) overall sound pressure level over the bandwidth of 50 Hz to 10,000 Hz. The chamber has a volume of 16,000 cubic feet with interior dimensions of 21.6 ft {times} 24.6 ft {times} 30 ft. The construction of the chamber should be complete by the summer of 1990. This paper discusses the design goals and constraints of the facility. The construction characteristics are discussed in detail, as are the acoustic performance design characteristics. The authors hope that this work will help others in designing acoustic chambers. 12 refs., 6 figs.

  18. Hydrocortisone Suppression of the Fear-potentiated Startle Response and Posttraumatic Stress Disorder

    PubMed Central

    Miller, Mark W.; McKinney, Ann E.; Kanter, Fredrick S.; Korte, Kristina J.; Lovallo, William R.

    2011-01-01

    This study examined the effects of oral administration of 20 mg hydrocortisone on baseline and fear-potentiated startle in 63 male veterans with or without PTSD. The procedure was based on a two-session, within-subject design in which acoustic startle eyeblink responses were recorded during intervals of threat or no threat of electric shock. Results showed that the magnitude of the difference between startle responses recorded during anticipation of imminent shock compared to “safe” periods was reduced after hydrocortisone administration relative to placebo. This effect did not vary as a function of PTSD group nor were there were any significant group differences in other indices startle amplitude. Findings suggest that the acute elevations in systemic cortisol produced by hydrocortisone administration may have fear-inhibiting effects. This finding may have implications for understanding the role of hypothalamic-pituitary-adrenal (HPA)-axis function in vulnerability and resilience to traumatic stress. PMID:21269779

  19. Overview of the Ares I Scale Model Acoustic Test Program

    NASA Technical Reports Server (NTRS)

    Counter, Douglas D.; Houston, Janice D.

    2011-01-01

    Launch environments, such as lift-off acoustic (LOA) and ignition overpressure (IOP), are important design factors for any vehicle and are dependent upon the design of both the vehicle and the ground systems. LOA environments are used directly in the development of vehicle vibro-acoustic environments and IOP is used in the loads assessment. The NASA Constellation Program had several risks to the development of the Ares I vehicle linked to LOA. The risks included cost, schedule and technical impacts for component qualification due to high predicted vibro-acoustic environments. One solution is to mitigate the environment at the component level. However, where the environment is too severe for component survivability, reduction of the environment itself is required. The Ares I Scale Model Acoustic Test (ASMAT) program was implemented to verify the Ares I LOA and IOP environments for the vehicle and ground systems including the Mobile Launcher (ML) and tower. An additional objective was to determine the acoustic reduction for the LOA environment with an above deck water sound suppression system. ASMAT was a development test performed at the Marshall Space Flight Center (MSFC) East Test Area (ETA) Test Stand 116 (TS 116). The ASMAT program is described in this presentation.

  20. The Nozzle Acoustic Test Rig: an Acoustic and Aerodynamic Free-jet Facility

    NASA Technical Reports Server (NTRS)

    Castner, Raymond S.

    1994-01-01

    The nozzle acoustic test rig (NATR) was built at NASA Lewis Research Center to support the High Speed Research Program. The facility is capable of measuring the acoustic and aerodynamic performance of aircraft engine nozzle concepts. Trade-off studies are conducted to compare performance and noise during simulated low-speed flight and takeoff. Located inside an acoustically treated dome with a 62-ft radius, the NATR is a free-jet that has a 53-in. diameter and is driven by an air ejector. This ejector is operated with 125 lb/s of compressed air, at 125 psig, to achieve 375 lb/s at Mach 0.3. Acoustic and aerodynamic data are collected from test nozzles mounted in the free-jet flow. The dome serves to protect the surrounding community from high noise levels generated by the nozzles, and to provide an anechoic environment for acoustic measurements. Information presented in this report summarizes free-jet performance, fluid support systems, and data acquisition capabilities of the NATR.

  1. Vibration and acoustic testing of TOPEX/Poseidon satellite

    NASA Technical Reports Server (NTRS)

    Boatman, Dave; Scharton, Terry; Hershfeld, Donald; Larkin, Paul

    1992-01-01

    The satellite was subjected to a 1.5G swept sine vibration test and a 146 dB overall level acoustic test, in accordance with Ariane launch vehicle requirements, at the NASA Goddard Space Flight Center. Extensive pretest analysis of the sine test was conducted to plan the input notching and to justify vibration testing the satellite only in the longitudinal axis. A unique measurement system was utilized to determine the six components of interface force between the shaker and the satellite in the sine vibration test. The satellite was heavily instrumented in both the sine vibration and acoustic test in order to insure that the launch loads were enveloped with appropriate margin and that satellite responses did not exceed the compatibilities of the structure and equipment. The test specification, objectives, instrumentation, and test results are described herein.

  2. Vibration and acoustic testing of TOPEX/Poseidon satellite

    NASA Astrophysics Data System (ADS)

    Boatman, Dave; Scharton, Terry; Hershfeld, Donald; Larkin, Paul

    1992-11-01

    The satellite was subjected to a 1.5G swept sine vibration test and a 146 dB overall level acoustic test, in accordance with Ariane launch vehicle requirements, at the NASA Goddard Space Flight Center. Extensive pretest analysis of the sine test was conducted to plan the input notching and to justify vibration testing the satellite only in the longitudinal axis. A unique measurement system was utilized to determine the six components of interface force between the shaker and the satellite in the sine vibration test. The satellite was heavily instrumented in both the sine vibration and acoustic test in order to insure that the launch loads were enveloped with appropriate margin and that satellite responses did not exceed the compatibilities of the structure and equipment. The test specification, objectives, instrumentation, and test results are described herein.

  3. Development of a MEMS device for acoustic emission testing

    NASA Astrophysics Data System (ADS)

    Ozevin, Didem; Pessiki, Stephen P.; Jain, Akash; Greve, David W.; Oppenheim, Irving J.

    2003-08-01

    Acoustic emission testing is an important technology for evaluating structural materials, and especially for detecting damage in structural members. Significant new capabilities may be gained by developing MEMS transducers for acoustic emission testing, including permanent bonding or embedment for superior coupling, greater density of transducer placement, and a bundle of transducers on each device tuned to different frequencies. Additional advantages include capabilities for maintenance of signal histories and coordination between multiple transducers. We designed a MEMS device for acoustic emission testing that features two different mechanical types, a hexagonal plate design and a spring-mass design, with multiple detectors of each type at ten different frequencies in the range of 100 kHz to 1 MHz. The devices were fabricated in the multi-user polysilicon surface micromachining (MUMPs) process and we have conducted electrical characterization experiments and initial experiments on acoustic emission detection. We first report on C(V) measurements and perform a comparison between predicted (design) and measured response. We next report on admittance measurements conducted at pressures varying from vacuum to atmospheric, identifying the resonant frequencies and again providing a comparison with predicted performance. We then describe initial calibration experiments that compare the performance of the detectors to other acoustic emission transducers, and we discuss the overall performance of the device as a sensor suite, as contrasted to the single-channel performance of most commercial transducers.

  4. The Dornier 328 Acoustic Test Cell (ATC) for interior noise tests and selected test results

    NASA Technical Reports Server (NTRS)

    Hackstein, H. Josef; Borchers, Ingo U.; Renger, Klaus; Vogt, Konrad

    1992-01-01

    To perform acoustic studies for achieving low noise levels for the Dornier 328, an acoustic test cell (ATC) of the Dornier 328 has been built. The ATC consists of a fuselage section, a realistic fuselage suspension system, and three exterior noise simulation rings. A complex digital 60 channel computer/amplifier noise generation system as well as multichannel digital data acquisition and evaluation system have been used. The noise control tests started with vibration measurements for supporting acoustic data interpretation. In addition, experiments have been carried out on dynamic vibration absorbers, the most important passive noise reduction measure for low frequency propeller noise. The design and arrangement of the current ATC are presented. Furthermore, exterior noise simulation as well as data acquisition are explained. The most promising results show noise reduction due to synchrophasing and dynamic vibration absorbers.

  5. Computer-controlled noise adaption for acoustical test facilities

    NASA Astrophysics Data System (ADS)

    Wedig, W. V.; Ams, A.

    1990-09-01

    For acoustical noise tests of elastic structures, statistically representative signals generated from white noise by means of spectrum shapers and band pass filters are needed. Subsequently, these signals are amplified and transformed into physical test noise by acoustical sirens. A mathematical model of the entire system based on measurements of frequency transfer functions in order to predict an optimal amplitude modulation of the spectrum shaper is presented. The prediction is performed by means of a nonlinear optimization procedure which iterates the tuning parameters of the shaper with respect to the stored frequency data of the entire system.

  6. Acoustics

    NASA Technical Reports Server (NTRS)

    Goodman, Jerry R.; Grosveld, Ferdinand

    2007-01-01

    The acoustics environment in space operations is important to maintain at manageable levels so that the crewperson can remain safe, functional, effective, and reasonably comfortable. High acoustic levels can produce temporary or permanent hearing loss, or cause other physiological symptoms such as auditory pain, headaches, discomfort, strain in the vocal cords, or fatigue. Noise is defined as undesirable sound. Excessive noise may result in psychological effects such as irritability, inability to concentrate, decrease in productivity, annoyance, errors in judgment, and distraction. A noisy environment can also result in the inability to sleep, or sleep well. Elevated noise levels can affect the ability to communicate, understand what is being said, hear what is going on in the environment, degrade crew performance and operations, and create habitability concerns. Superfluous noise emissions can also create the inability to hear alarms or other important auditory cues such as an equipment malfunctioning. Recent space flight experience, evaluations of the requirements in crew habitable areas, and lessons learned (Goodman 2003; Allen and Goodman 2003; Pilkinton 2003; Grosveld et al. 2003) show the importance of maintaining an acceptable acoustics environment. This is best accomplished by having a high-quality set of limits/requirements early in the program, the "designing in" of acoustics in the development of hardware and systems, and by monitoring, testing and verifying the levels to ensure that they are acceptable.

  7. Vibro-Acoustics Modal Testing at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Pappa, Richard S.; Pritchard, Jocelyn I.; Buehrle, Ralph D.

    1999-01-01

    This paper summarizes on-going modal testing activities at the NASA Langley Research Center for two aircraft fuselage structures: a generic "aluminum testbed cylinder" (ATC) and a Beechcraft Starship fuselage (BSF). Subsequent acoustic tests will measure the interior noise field created by exterior mechanical and acoustic sources. These test results will provide validation databases for interior noise prediction codes on realistic aircraft fuselage structures. The ATC is a 12-ft-long, all-aluminum, scale model assembly. The BSF is a 40-ft-long, all-composite, complete aircraft fuselage. To date, two of seven test configurations of the ATC and all three test configurations of the BSF have been completed. The paper briefly describes the various test configurations, testing procedure, and typical results for frequencies up to 250 Hz.

  8. Digital control of high-intensity acoustic testing. [for spacecraft

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1975-01-01

    Three systems for the control of acoustic testing are compared: a hybrid digital/analog system, a digital vibration system, and the same digital vibration system modified by a software change. The hybrid system was constructed to control the 1/3-octaves from 50 to 1000 Hz. The vibration system was equipped with programs for sine and random vibration tests, shock analysis and synthesis, and signal analysis. For the modified vibration system, the random-vibration control program of the unmodified unit was changed so that acoustic tests could be performed. The performance of the three systems is compared by conducting probability-density and time-history analyses of the proposed test spectrum for the Mariner Jupiter/Saturn 1977 program. The results of the analyses show that the hybrid and modified vibration systems perform almost equally, but the modified vibration system is easier to use and produces better test documentation.

  9. Results of acoustic emission tests on Halon fire bottles

    SciTech Connect

    Beattie, A.G.; Shurtleff, W.W.

    1996-10-01

    An acoustic emission tester for aircraft Halon bottles has been developed. The necessary load is applied by heating the bottles. Acoustic emission is monitored during the heating by six sensors held in position by a special fixture. This fixture was designed to fit spheres with diameters between 5 and 16 inches. A prototype has been undergoing testing in two commercial Halon bottle repair and test facilities. Results to date indicate that about 97 percent of the bottles tested show no indications of any flaws. The other three percent have had indications of flaws in non-critical areas of the bottles. All bottles tested to date have passed the hydrostatic test required by the Department of Transportation (DOT).

  10. An Evaluation of the Additional Acoustic Power Needed to Overcome the Effects of a Test-Article's Absorption during Reverberant Chamber Acoustic Testing of Spaceflight Hardware

    NASA Technical Reports Server (NTRS)

    Hozman, Aron D.; Hughes, William O.

    2014-01-01

    The exposure of a customers aerospace test-article to a simulated acoustic launch environment is typically performed in a reverberant acoustic test chamber. The acoustic pre-test runs that will ensure that the sound pressure levels of this environment can indeed be met by a test facility are normally performed without a test-article dynamic simulator of representative acoustic absorption and size. If an acoustic test facilitys available acoustic power capability becomes maximized with the test-article installed during the actual test then the customers environment requirement may become compromised. In order to understand the risk of not achieving the customers in-tolerance spectrum requirement with the test-article installed, an acoustic power margin evaluation as a function of frequency may be performed by the test facility. The method for this evaluation of acoustic power will be discussed in this paper. This method was recently applied at the NASA Glenn Research Center Plum Brook Stations Reverberant Acoustic Test Facility for the SpaceX Falcon 9 Payload Fairing acoustic test program.

  11. An Evaluation of the Additional Acoustic Power Needed to Overcome the Effects of a Test-Article's Absorption During Reverberant Chamber Acoustic Testing of Spaceflight Hardware

    NASA Technical Reports Server (NTRS)

    Hozman, Aron D.; Hughes, William O.

    2014-01-01

    The exposure of a customer's aerospace test-article to a simulated acoustic launch environment is typically performed in a reverberant acoustic test chamber. The acoustic pre-test runs that will ensure that the sound pressure levels of this environment can indeed be met by a test facility are normally performed without a test-article dynamic simulator of representative acoustic absorption and size. If an acoustic test facility's available acoustic power capability becomes maximized with the test-article installed during the actual test then the customer's environment requirement may become compromised. In order to understand the risk of not achieving the customer's in-tolerance spectrum requirement with the test-article installed, an acoustic power margin evaluation as a function of frequency may be performed by the test facility. The method for this evaluation of acoustic power will be discussed in this paper. This method was recently applied at the NASA Glenn Research Center Plum Brook Station's Reverberant Acoustic Test Facility for the SpaceX Falcon 9 Payload Fairing acoustic test program.

  12. Direct gaze of photographs of female nudes influences startle in men.

    PubMed

    Lass-Hennemann, Johanna; Schulz, André; Nees, Frauke; Blumenthal, Terry D; Schachinger, Hartmut

    2009-05-01

    Foreground presentation of photographs of opposite sex nudes lowers startle elicited by sudden acoustic stimuli. However, the impact of gaze direction of the presented nudes on this startle modulation has not been investigated. Theoretically, direct gaze of photographs of female nudes could either lead to a larger inhibition of the startle reaction due to a summating valence and arousal effect of direct eye contact, or lead to a smaller inhibition due to an attention capturing effect of the eyes. Two subsets of erotic photographs of female nudes (women looking directly at the observer vs. gazing away) and standard IAPS neutral pictures were viewed by 26 male volunteers, while startle eye blink responses to binaural bursts of white noise (50 ms, 105 dB) were recorded by EMG. Erotic pictures reduced startle eyeblink magnitude as compared to neutral pictures. Furthermore, erotic stimuli without direct gaze at the observer showed a greater startle eyeblink inhibition than erotic stimuli with direct gaze at the observer. Our data suggest that direct gaze of opposite sex nudes may direct attention to the face, thereby reducing the appetitive impact of an attractive body.

  13. Seismic, Acoustic, and Magnetic Test Results from US/German Testing

    DTIC Science & Technology

    1999-01-01

    SEISMIC, ACOUSTIC, AND MAGNETIC TEST RESULTS FROM US/GERMAN TESTING John Sledge CHICKEN LITTLE Program Office Eglin AFB Florida 32542 ABSTRACT...conducted at the Meppen Test Range during the period of October 1997. The CHICKEN LITTLE, Sensor/Seeker Seismic, Acoustic, and Magnetic (SAM) team...Number Performing Organization Name(s) and Address(es) CHICKEN LITTLE Program Office Eglin AFB Florida 32542 Performing Organization Number(s

  14. Acoustic results of the Boeing model 360 whirl tower test

    NASA Technical Reports Server (NTRS)

    Watts, Michael E.; Jordan, David

    1990-01-01

    An evaluation is presented for whirl tower test results of the Model 360 helicopter's advanced, high-performance four-bladed composite rotor system intended to facilitate over-200-knot flight. During these performance measurements, acoustic data were acquired by seven microphones. A comparison of whirl-tower tests with theory indicate that theoretical prediction accuracies vary with both microphone position and the inclusion of ground reflection. Prediction errors varied from 0 to 40 percent of the measured signal-to-peak amplitude.

  15. Structural tests using a MEMS acoustic emission sensor

    NASA Astrophysics Data System (ADS)

    Oppenheim, Irving J.; Greve, David W.; Ozevin, Didem; Hay, D. Robert; Hay, Thomas R.; Pessiki, Stephen P.; Tyson, Nathan L.

    2006-03-01

    In a collaborative project at Lehigh and Carnegie Mellon, a MEMS acoustic emission sensor was designed and fabricated as a suite of six resonant-type capacitive transducers in the frequency range between 100 and 500 kHz. Characterization studies showed good comparisons between predicted and experimental electro-mechanical behavior. Acoustic emission events, simulated experimentally in steel ball impact and in pencil lead break tests, were detected and source localization was demonstrated. In this paper we describe the application of the MEMS device in structural testing, both in laboratory and in field applications. We discuss our findings regarding housing and mounting (acoustic coupling) of the MEMS device with its supporting electronics, and we then report the results of structural testing. In all tests, the MEMS transducers were used in parallel with commercial acoustic emission sensors, which thereby serve as a benchmark and permit a direct observation of MEMS device functionality. All tests involved steel structures, with particular interest in propagation of existing cracks or flaws. A series of four laboratory tests were performed on beam specimens fabricated from two segments (Grade 50 steel) with a full penetration weld (E70T-4 electrode material) at midspan. That weld region was notched, an initial fatigue crack was induced, and the specimens were then instrumented with one commercial transducer and with one MEMS device; data was recorded from five individual transducers on the MEMS device. Under a four-point bending test, the beam displayed both inelastic behavior and crack propagation, including load drops associated with crack instability. The MEMS transducers detected all instability events as well as many or most of the acoustic emissions occurring during plasticity and stable crack growth. The MEMS transducers were less sensitive than the commercial transducer, and did not detect as many events, but the normalized cumulative burst count obtained

  16. Tip aerodynamics and acoustics test: A report and data survey

    NASA Technical Reports Server (NTRS)

    Cross, Jeffrey L.; Watts, Michael E.

    1988-01-01

    In a continuing effort to understand helicopter rotor tip aerodynamics and acoustics, a flight test was conducted by NASA Ames Research Center. The test was performed using the NASA White Cobra and a set of highly instrumented blades. All aspects of the flight test instrumentation and test procedures are explained. Additionally, complete data sets for selected test points are presented and analyzed. Because of the high volume of data acquired, only selected data points are presented. However, access to the entire data set is available to the researcher on request.

  17. Acoustic and Aerothermal Performance Test of the Axisymmetric Coannular Ejector Nozzle. Volume 2; Acoustic Performance

    NASA Technical Reports Server (NTRS)

    Herkes, William

    2000-01-01

    Acoustic and propulsion performance testing of a model-scale Axisymmetric Coannular Ejector nozzle was conducted in the Boeing Low-speed Aeroacoustic Facility. This nozzle is a plug nozzle with an ejector design to provide aspiration of about 20% of the engine flow. A variety of mixing enhancers were designed to promote mixing of the engine and the aspirated flows. These included delta tabs, tone-injection rods, and wheeler ramps. This report addresses the acoustic aspects of the testing. The spectral characteristics of the various configurations of the nozzle are examined on a model-scale basis. This includes indentifying particular noise sources contributing to the spectra and the data are projected to full-scale flyover conditions to evaluate the effectiveness of the nozzle, and of the various mixing enhancers, on reducing the Effective Perceived Noise Levels.

  18. Affective Influences on Startle in Five-Month-Old Infants: Reactions to Facial Expressions of Emotion.

    ERIC Educational Resources Information Center

    Balaban, Marie T.

    1995-01-01

    While 18 5-month-old infants viewed photographic slides of faces posed in happy, neutral, or angry expressions, a brief acoustic noise burst was presented to elicit the blink component of human startle. It was found that blink size was augmented during the viewing of angry expressions and reduced during viewing of happy expressions. (MDM)

  19. Ares I Scale Model Acoustic Test Above Deck Water Sound Suppression Results

    NASA Technical Reports Server (NTRS)

    Counter, Douglas D.; Houston, Janice D.

    2011-01-01

    The Ares I Scale Model Acoustic Test (ASMAT) program test matrix was designed to determine the acoustic reduction for the Liftoff acoustics (LOA) environment with an above deck water sound suppression system. The scale model test can be used to quantify the effectiveness of the water suppression system as well as optimize the systems necessary for the LOA noise reduction. Several water flow rates were tested to determine which rate provides the greatest acoustic reductions. Preliminary results are presented.

  20. Could Acoustic Emission Testing Show a Pipe Failure in Advance?

    NASA Astrophysics Data System (ADS)

    Soares, S. D.; Teixeira, J. C. G.

    2004-02-01

    During the last 20 years PETROBRAS has been attempting to use Acoustic Emission (AE) as an inspection tool. In this period the AE concept has changed from a revolutionary method to a way of finding areas to make a complete inspection. PETROBRAS has a lot of pressure vessels inspected by AE and with other NDTs techniques to establish their relationship. In other hand, PETROBRAS R&D Center has conducted destructive hydrostatic tests in pipelines samples with artificial defects made by milling. Those tests were monitored by acoustic emission and manual ultrasonic until the complete failure of pipe sample. This article shows the results obtained and a brief proposal of analysis criteria for this environment of test.

  1. Deficits in startle-evoked arm movements increase with impairment following stroke

    PubMed Central

    Honeycutt, Claire Fletcher; Perreault, Eric Jon

    2014-01-01

    Objective The startle reflex elicits involuntary release of planned movements (startReact). Following stroke, startReact flexion movements are intact but startReact extension movements are impaired by task-inappropriate flexor activity impeding arm extension. Our objective was to quantify deficits in startReact elbow extension movements, particularly how these deficits are influenced by impairment. Methods Data were collected in 8 stroke survivors performing elbow extension following two non-startling acoustic stimuli representing “get ready” and “go” respectively. Randomly, the “go” was replaced with a startling acoustic stimulus. We hypothesized that task-inappropriate flexor activity originates from unsuppressed classic startle reflex. We expected that increasing damage to the cortex (increasing impairment) would relate to increasing task-inappropriate flexor activity causing poor elbow extension movement and target acquisition. Results Task-inappropriate flexor activity increased with impairment resulting in larger flexion deflections away from the subjects’ intended target corresponding to decreased target acquisition. Conclusions We conclude that the task-inappropriate flexor activity likely results from cortical or corticospinal damage leading to an unsuppressed or hypermetric classic startle reflex that interrupts startReact elbow extension. Significance Given startReact’s functional role in compensation during environmental disturbances, our results may have important implications for our understanding deficits in stroke survivor’s response to unexpected environmental disturbances. PMID:24411525

  2. The serotonin transporter gene and startle response during nicotine deprivation.

    PubMed

    Minnix, Jennifer A; Robinson, Jason D; Lam, Cho Y; Carter, Brian L; Foreman, Jennifer E; Vandenbergh, David J; Tomlinson, Gail E; Wetter, David W; Cinciripini, Paul M

    2011-01-01

    Affective startle probe methodology was used to examine the effects of nicotine administration and deprivation on emotional processes among individuals carrying at least one s allele versus those with the l/l genotype of the 5-Hydroxytryptamine (Serotonin) Transporter Linked Polymorphic Region, 5-HTTLPR in the promoter region of the serotonin transporter gene [solute ligand carrier family 6 member A4 (SLC6A4) or SERT]. Smokers (n=84) completed four laboratory sessions crossing deprivation (12-h deprived vs. non-deprived) with nicotine spray (nicotine vs. placebo). Participants viewed affective pictures (positive, negative, neutral) while acoustic startle probes were administered. We found that smokers with the l/l genotype showed significantly greater suppression of the startle response when provided with nicotine vs. placebo than those with the s/s or s/l genotypes. The results suggest that l/l smokers, who may have higher levels of the serotonin transporter and more rapid synaptic serotonin clearance, experience substantial reduction in activation of the defensive system when exposed to nicotine.

  3. Vibration and Acoustic Testing for Mars Micromission Spacecraft

    NASA Technical Reports Server (NTRS)

    Kern, Dennis L.; Scharton, Terry D.

    1999-01-01

    The objective of the Mars Micromission program being managed by the Jet Propulsion Laboratory (JPL) for NASA is to develop a common spacecraft that can carry telecommunications equipment and a variety of science payloads for exploration of Mars. The spacecraft will be capable of carrying robot landers and rovers, cameras, probes, balloons, gliders or aircraft, and telecommunications equipment to Mars at much lower cost than recent NASA Mars missions. The lightweight spacecraft (about 220 Kg mass) will be launched in a cooperative venture with CNES as a TWIN auxiliary payload on the Ariane 5 launch vehicle. Two or more Mars Micromission launches are planned for each Mars launch opportunity, which occur every 26 months. The Mars launch window for the first mission is November 1, 2002 through April 2003, which is planned to be a Mars airplane technology demonstration mission to coincide with the 100 year anniversary of the Kittyhawk flight. Several subsequent launches will create a telecommunications network orbiting Mars, which will provide for continuous communication with lenders and rovers on the Martian surface. Dedicated science payload flights to Mars are slated to start in 2005. This new cheaper and faster approach to Mars exploration calls for innovative approaches to the qualification of the Mars Micromission spacecraft for the Ariane 5 launch vibration and acoustic environments. JPL has in recent years implemented new approaches to spacecraft testing that may be effectively applied to the Mars Micromission. These include 1) force limited vibration testing, 2) combined loads, vibration and modal testing, and 3) direct acoustic testing. JPL has performed nearly 200 force limited vibration tests in the past 9 years; several of the tests were on spacecraft and large instruments, including the Cassini and Deep Space One spacecraft. Force limiting, which measures and limits the spacecraft base reaction force using triaxial force gages sandwiched between the

  4. Field tests of acoustic telemetry for a portable coastal observatory

    USGS Publications Warehouse

    Martini, M.; Butman, B.; Ware, J.; Frye, D.

    2006-01-01

    Long-term field tests of a low-cost acoustic telemetry system were carried out at two sites in Massachusetts Bay. At each site, an acoustic Doppler current profiler mounted on a bottom tripod was fitted with an acoustic modem to transmit data to a surface buoy; electronics mounted on the buoy relayed these data to shore via radio modem. The mooring at one site (24 m water depth) was custom-designed for the telemetry application, with a custom designed small buoy, a flexible electro-mechanical buoy to mooring joint using a molded chain connection to the buoy, quick-release electro-mechanical couplings, and dual hydrophones suspended 7 m above the bottom. The surface buoy at the second site (33 m water depth) was a U.S. Coast Guard (USCG) channel buoy fitted with telemetry electronics and clamps to hold the hydrophones. The telemetry was tested in several configurations for a period of about four years. The custom-designed buoy and mooring provided nearly error-free data transmission through the acoustic link under a variety of oceanographic conditions for 261 days at the 24 m site. The electro mechanical joint, cables and couplings required minimal servicing and were very reliable, lasting 862 days deployed before needing repairs. The acoustic communication results from the USCG buoy were poor, apparently due to the hard cobble bottom, noise from the all-steel buoy, and failure of the hydrophone assembly. Access to the USCG buoy at sea required ideal weather. ??2006 IEEE.

  5. Motor cortex inhibition induced by acoustic stimulation.

    PubMed

    Kühn, Andrea A; Sharott, Andrew; Trottenberg, Thomas; Kupsch, Andreas; Brown, Peter

    2004-09-01

    The influence of the brainstem motor system on cerebral motor areas may play an important role in motor control in health and disease. A new approach to investigate this interaction in man is combining acoustic stimulation activating the startle system with transcranial magnetic stimulation (TMS) over the motor cortex. However, it is unclear whether the inhibition of TMS responses following acoustic stimulation occurs at the level of the motor cortex through reticulo-cortical projections or subcortically, perhaps through reticulo-spinal projections. We compared the influence of acoustic stimulation on motor effects elicited by TMS over motor cortical areas to those evoked with subcortical electrical stimulation (SES) through depth electrodes in five patients treated with deep brain stimulation for Parkinson's disease. SES bypasses the motor cortex, demonstrating any interaction with acoustic stimuli at the subcortical level. EMG was recorded from the contralateral biceps brachii muscle. Acoustic stimulation was delivered binaurally through headphones and used as a conditioning stimulus at an interstimulus interval of 50 ms. When TMS was used as the test stimulus, the area and amplitude of the conditioned motor response was significantly inhibited (area: 57.5+/-12.9%, amplitude: 47.9+/-7.4%, as percentage of unconditioned response) whereas facilitation occurred with SES (area: 110.1+/-4.3%, amplitude: 116.9+/-6.9%). We conclude that a startle-evoked activation of reticulo-cortical projections transiently inhibits the motor cortex.

  6. Design and manufacturing of scanning probe acoustic microscope test phantom

    NASA Astrophysics Data System (ADS)

    Chen, Xiaohui; Fang, Xiaoyue; Song, Jitao; Ding, Mingyue

    2015-03-01

    Acquiring nondestructive internal structures acoustic image as well as the morphology images using scanning probe acoustic microscope (SPAM) is a challenge and no known metrology tools to identify the ultrasonic internal resolution and detectable depth of SPAM in a nondestructive way. Monitoring these defects necessitates the identification of their technical parameters of SPAM. In this paper, the specific materials (test phantoms) were designed and processed so that the ultrasound internal resolution of SPAM in nondestructive imaging of the embedded or buried substructures as well as the morphology images were measured. Experimental results demonstrated the successful identification of embedded or buried defects under the test phantom with the resolution of 50nm for SPAM as well as the detectable depth of more than 100μm.

  7. NASA Engineering and Safety Center (NESC) Enhanced Melamine (ML) Foam Acoustic Test (NEMFAT)

    NASA Technical Reports Server (NTRS)

    McNelis, Anne M.; Hughes, William O.; McNelis, Mark E.

    2014-01-01

    The NASA Engineering and Safety Center (NESC) funded a proposal to achieve initial basic acoustic characterization of ML (melamine) foam, which could serve as a starting point for a future, more comprehensive acoustic test program for ML foam. A project plan was developed and implemented to obtain acoustic test data for both normal and enhanced ML foam. This project became known as the NESC Enhanced Melamine Foam Acoustic Test (NEMFAT). This document contains the outcome of the NEMFAT project.

  8. LATTE - Linking Acoustic Tests and Tagging Using Statistical Estimation

    DTIC Science & Technology

    2013-09-30

    after C. Harris’ maternity leave. WORK COMPLETED The project started in April 2010. Task 3 (data processing) is now essentially over, and task 4...Marques et al. An overview of LATTE: Linking Acoustic Tests and Tagging using statistical Estimation: Modelling the Behaviour of Beaked Whales in...geometric (Figure 2). 5 Figure 2 – Conceptual description of the dive cycle of a beaked whale considering 7 behavioural states: 1. At the

  9. Hybrid Wing Body Aircraft Acoustic Test Preparations and Facility Upgrades

    NASA Technical Reports Server (NTRS)

    Heath, Stephanie L.; Brooks, Thomas F.; Hutcheson, Florence V.; Doty, Michael J.; Haskin, Henry H.; Spalt, Taylor B.; Bahr, Christopher J.; Burley, Casey L.; Bartram, Scott M.; Humphreys, William M.; Lunsford, Charles B.; Popenack, Thomas G.; Colbert, Scott E.; Hoad, Danny; Becker, Lawrence; Stead, Dan; Kuchta, Dennis; Yeh, Les

    2013-01-01

    NASA is investigating the potential of acoustic shielding as a means to reduce the noise footprint at airport communities. A subsonic transport aircraft and Langley's 14- by 22-foot Subsonic Wind Tunnel were chosen to test the proposed "low noise" technology. The present experiment studies the basic components of propulsion-airframe shielding in a representative flow regime. To this end, a 5.8-percent scale hybrid wing body model was built with dual state-of-the-art engine noise simulators. The results will provide benchmark shielding data and key hybrid wing body aircraft noise data. The test matrix for the experiment contains both aerodynamic and acoustic test configurations, broadband turbomachinery and hot jet engine noise simulators, and various airframe configurations which include landing gear, cruise and drooped wing leading edges, trailing edge elevons and vertical tail options. To aid in this study, two major facility upgrades have occurred. First, a propane delivery system has been installed to provide the acoustic characteristics with realistic temperature conditions for a hot gas engine; and second, a traversing microphone array and side towers have been added to gain full spectral and directivity noise characteristics.

  10. Helicopter Acoustic Flight Test with Altitude Variation and Maneuvers

    NASA Technical Reports Server (NTRS)

    Watts, Michael E.; Greenwood, Eric; Sim, Ben; Stephenson, James; Smith, Charles D.

    2016-01-01

    A cooperative flight test campaign between NASA and the U.S. Army was performed from September 2014 to February 2015. The purposes of the testing were to: investigate the effects of altitude variation on noise generation, investigate the effects of gross weight variation on noise generation, establish the statistical variability in acoustic flight testing of helicopters, and characterize the effects of transient maneuvers on radiated noise for a medium-lift utility helicopter. This test was performed at three test sites (0, 4000, and 7000 feet above mean sea level) with two aircraft (AS350 SD1 and EH-60L) tested at each site. This report provides an overview of the test, documents the data acquired and describes the formats of the stored data.

  11. NASA Glenn Research Center Acoustical Testing Laboratory: Five year retrospective

    NASA Astrophysics Data System (ADS)

    Cooper, Beth A.; Akers, James C.; Passe, Paul J.

    2005-09-01

    In the five years since the NASA Glenn Research Center Acoustical Testing Laboratory (ATL) opened its doors in September, 2000, it has developed a comprehensive array of services and products that support hearing conservation goals within NASA and industry. The ATL provides acoustic emission testing and noise control engineering services for a variety of specialized customers, particularly developers of equipment and science experiments manifested for NASA's manned space missions. The ATL aggressively supports the vision of a low-noise on-orbit environment, which facilitates mission success as well as crew health, safety, and comfort. In concert with these goals, the ATL also produces and distributes free educational resources and low-noise advocacy tools for hearing conservation education and awareness. Among these are two compact discs of auditory demonstrations (of phenomena in acoustics, hearing conservation, and communication), and presentations, software packages, and other educational materials for use by engineers, audiologists, and other hearing conservation stakeholders. This presentation will highlight ATL's construction, history, technical capabilities, and current projects and will feature demonstrations of some of the unique educational resource materials that are distributed by the ATL.

  12. Acoustic emission testing of 12-nickel maraging steel pressure vessels

    NASA Technical Reports Server (NTRS)

    Dunegan, H. L.

    1973-01-01

    Acoustic emission data were obtained from three point bend fracture toughness specimens of 12-nickel maraging steel, and two pressure vessels of the same material. One of the pressure vessels contained a prefabricated flaw which was extended and sharpened by fatigue cycling. It is shown that the flawed vessel had similar characteristics to the fracture specimens, thereby allowing estimates to be made of its nearness to failure during a proof test. Both the flawed and unflawed pressure vessel survived the proof pressure and 5 cycles to the working pressure, but it was apparent from the acoustic emission response during the proof cycle and the 5 cycles to the working pressure that the flawed vessel was very near failure. The flawed vessel did not survive a second cycle to the proof pressure before failure due to flaw extension through the wall (causing a leak).

  13. Adaptation to Room Acoustics Using the Modified Rhyme Test

    PubMed Central

    Brandewie, Eugene; Zahorik, Pavel

    2012-01-01

    The negative effect of reverberant sound energy on speech intelligibility is well documented. Recently, however, prior exposure to room acoustics has been shown to increase intelligibility for a number of listeners in simulated room environments. This room adaptation effect, a possible extension of dynamic echo suppression, has been shown to be specific to reverberant rooms and requires binaural input. Because this effect has been demonstrated only using the Coordinated Response Measure (CRM) corpus it is important to determine whether the increase in intelligibility scores reported previously was due to the specific nature of the CRM task. Here we demonstrate a comparable room-acoustic effect using the Modified Rhyme Test (MRT) corpus in multiple room environments. The results are consistent with the idea that the room adaptation effect may be a natural phenomenon of listening in reverberant environments. PMID:23437415

  14. Vibration and Acoustic Test Facility (VATF): User Test Planning Guide

    NASA Technical Reports Server (NTRS)

    Fantasia, Peter M.

    2011-01-01

    Test process, milestones and inputs are unknowns to first-time users of the VATF. The User Test Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their test engineering personnel in test planning and execution. Material covered includes a roadmap of the test process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, test article interfaces, and inputs necessary to define test scope, cost, and schedule are included as an appendix to the guide.

  15. Development of a model of startle resulting from exposure to sonic booms

    NASA Astrophysics Data System (ADS)

    Marshall, Andrew J.

    Aircraft manufacturers believe that it is possible to create supersonic business jets that would have quieter sonic booms than those that lead to the current ban on overland commercial supersonic flight over the US. In order to assess if the impact of these "low booms" is acceptable to the public, new human subject testing must occur. In recent studies, it was found that subjects' judgments of annoyance were highly correlated to judgments of startle and were unable to be fully explained by loudness judgments alone. However, this experiment utilized earphones for playback, which was unable to reproduce low frequencies (< 25 Hz) well. Building upon this study, an additional semantic differential experiment was conducted using a sonic boom simulator for playback which could reproduce these frequency components. Results of both experiments were similar and again it was found that average startle and annoyance ratings were highly correlated and that statistics of time-varying loudness were highly correlated with subjects' responses. However, it was unclear if subjects' judgments of startle corresponded to physiological responses associated with startle. To examine if physiological responses associated with startle were evoked by the low booms, two studies were conducted; a pilot study and a repeatability study. While physiological responses associated with startle were evoked by low booms, startle responses were found to have occurred infrequently. However, subjects' judgments of startle were found to be correlated with physiological responses and to have less day-to-day and subject to-subject variance. Candidate startle models were estimated from data obtained from an experiment where subjects' judged the startle evoked by a series of low amplitude sonic booms and boom-like noises. These candidate startle models were then tested in an additional study which used a more diverse set of stimuli. It was found that a linear model consisting of the maximum long-term Moore

  16. Acoustic tests of duct-burning turbofan jet noise simulation

    NASA Technical Reports Server (NTRS)

    Knott, P. R.; Stringas, E. J.; Brausch, J. F.; Staid, P. S.; Heck, P. H.; Latham, D.

    1978-01-01

    The results of a static acoustic and aerodynamic performance, model-scale test program on coannular unsuppressed and multielement fan suppressed nozzle configurations are summarized. The results of the static acoustic tests show a very beneficial interaction effect. When the measured noise levels were compared with the predicted noise levels of two independent but equivalent conical nozzle flow streams, noise reductions for the unsuppressed coannular nozzles were of the order of 10 PNdB; high levels of suppression (8 PNdB) were still maintained even when only a small amount of core stream flow was used. The multielement fan suppressed coannular nozzle tests showed 15 PNdB noise reductions and up to 18 PNdB noise reductions when a treated ejector was added. The static aerodynamic performance tests showed that the unsuppressed coannular plug nozzles obtained gross thrust coefficients of 0.972, with 1.2 to 1.7 percent lower levels for the multielement fan-suppressed coannular flow nozzles. For the first time anywhere, laser velocimeter velocity profile measurements were made on these types of nozzle configurations and with supersonic heated flow conditions. Measurements showed that a very rapid decay in the mean velocity occurs for the nozzle tested.

  17. Acoustic-Structure Interaction in Rocket Engines: Validation Testing

    NASA Technical Reports Server (NTRS)

    Davis, R. Benjamin; Joji, Scott S.; Parks, Russel A.; Brown, Andrew M.

    2009-01-01

    While analyzing a rocket engine component, it is often necessary to account for any effects that adjacent fluids (e.g., liquid fuels or oxidizers) might have on the structural dynamics of the component. To better characterize the fully coupled fluid-structure system responses, an analytical approach that models the system as a coupled expansion of rigid wall acoustic modes and in vacuo structural modes has been proposed. The present work seeks to experimentally validate this approach. To experimentally observe well-coupled system modes, the test article and fluid cavities are designed such that the uncoupled structural frequencies are comparable to the uncoupled acoustic frequencies. The test measures the natural frequencies, mode shapes, and forced response of cylindrical test articles in contact with fluid-filled cylindrical and/or annular cavities. The test article is excited with a stinger and the fluid-loaded response is acquired using a laser-doppler vibrometer. The experimentally determined fluid-loaded natural frequencies are compared directly to the results of the analytical model. Due to the geometric configuration of the test article, the analytical model is found to be valid for natural modes with circumferential wave numbers greater than four. In the case of these modes, the natural frequencies predicted by the analytical model demonstrate excellent agreement with the experimentally determined natural frequencies.

  18. An Evaluation of the Additional Acoustic Power Needed to Overcome the Effects of a Test-Articles Absorption During Reverberant Chamber Acoustic Testing of Spaceflight Hardware

    NASA Technical Reports Server (NTRS)

    Hozman, Aron D.; Hughes, William O.

    2014-01-01

    It is important to realize that some test-articles may have significant sound absorption that may challenge the acoustic power capabilities of a test facility. Therefore, to mitigate this risk of not being able to meet the customers target spectrum, it is prudent to demonstrate early-on an increased acoustic power capability which compensates for this test-article absorption. This paper describes a concise method to reduce this risk when testing aerospace test-articles which have significant absorption. This method was successfully applied during the SpaceX Falcon 9 Payload Fairing acoustic test program at the NASA Glenn Research Center Plum Brook Stations RATF.

  19. Love wave acoustic sensor for testing in liquids

    NASA Astrophysics Data System (ADS)

    Pan, Haifeng; Zhu, Huizhong; Feng, Guanping

    2001-09-01

    Love wave is one type of the surface acoustic waves (SAWs). It is guided acoustic mode propagating in ta thin layer deposited on a substrate. Because of its advantages of high mass sensitivity, low noise level and being fit for operating in liquids, Love wave acoustic sensors have become one of the hot spots in the research of biosensor nowadays. In this paper the Love wave devices with the substrate of ST-cut quartz and the guiding layers of PMMA and fused quartz were fabricated successfully. By measuring the transfer function S21 and the insertion loss of the devices, the characteristics of the Rayleigh wave device and the Love wave devices with different guiding layers in gas phase and liquid phase were compared. It was validated that the Love wave sensor is suitable for testing in liquids but the Rayleigh wave sensor is not. What's more, SiO2 is the more proper material for the guiding layer of the Love wave device.

  20. Design and performance of the South Pole Acoustic Test Setup

    NASA Astrophysics Data System (ADS)

    Abdou, Y.; Becker, K.-H.; Berdermann, J.; Bissok, M.; Bohm, C.; Böser, S.; Bothe, M.; Carson, M.; Descamps, F.; Fischer-Wolfarth, J.-H.; Gustafsson, L.; Hallgren, A.; Heinen, D.; Helbing, K.; Heller, R.; Hundertmark, S.; Karg, T.; Krieger, K.; Laihem, K.; Meures, T.; Nahnhauer, R.; Naumann, U.; Oberson, F.; Paul, L.; Pohl, M.; Price, B.; Ribordy, M.; Ryckbosch, D.; Schunck, M.; Semburg, B.; Stegmaier, J.; Sulanke, K.-H.; Tosi, D.; Vandenbroucke, J.; Wiebusch, C.

    2012-08-01

    The South Pole Acoustic Test Setup (SPATS) was built to evaluate the acoustic characteristics of the South Pole ice in the 10-100 kHz frequency range, for the purpose of assessing the feasibility of an acoustic neutrino detection array at the South Pole. The SPATS hardware consists of four vertical strings deployed in the upper 500 m of the South Pole ice cap. The strings form a trapezoidal array with a maximum baseline of 543 m. Each string has seven stages equipped with one transmitter and one sensor module (glaciophone). Sound is detected or generated by piezoelectric ceramic elements inside the modules. Analogue signals are sent to the surface on electric cables where they are digitized by a PC-based data acquisition system. The data from all strings are collected on a central computer in the IceCube Laboratory from where they are sent to a central data storage facility via a satellite link or stored locally on tape. A technical overview of SPATS and its performance is presented.

  1. Acoustic Testing of Flight Hardware Using Loudspeakers: How Much do We Know About This Method of Testing?

    NASA Technical Reports Server (NTRS)

    Kolaini, Ali R.; Kern, Dennis L

    2011-01-01

    Loudspeakers have been used for acoustic qualification of spacecrafts, reflectors, solar panels, and other acoustically responsive structures for more than a decade. Even though a lot of hardware has been acoustic tested using this method, the nature of the acoustic field generated by controlling an ensemble of speakers with and without the hardware in the test volume has not been thoroughly investigated. Limited measurements from some of the recent speaker tests used to qualify flight hardware have indicated significant spatial variation of the acoustic field within the test volume. Also structural responses have been reported to differ when similar tests were performed using reverberant chambers. Unlike the reverberant chamber acoustic test, for which the acoustic field in most chambers is known to be diffuse except below several tens of Hz where acoustic standing waves and large spatial variations exist, the characteristics of the acoustic field within the speaker test volume has not been quantified. It has only been recently that a detailed acoustic field characterization of speaker testing has been made at Jet Propulsion Laboratory (JPL) with involvement of various organizations. To address the impact of non-uniform acoustic field on structures, a series of acoustic tests were performed using a flat panel and a 3-ft cylinder exposed to the field controlled by speakers and repeated in a reverberant chamber. The analysis of the data from this exercise reveals that there are significant differences both in the acoustic field and in the structural responses. In this paper the differences between the two methods are reviewed in some detail and the over- or under-testing of articles that could pose un-anticipated structural and flight qualification issues are discussed. A framework for discussing the validity of the speaker acoustic testing method with the current control system and a path forward for improving it will be provided.

  2. Variables involved in the cue modulation of the startle reflex in alcohol-dependent patients.

    PubMed

    Rubio, Gabriel; Borrell, José; Jiménez, Mónica; Jurado, Rosa; Grüsser, Sabine M; Heinz, Andreas

    2013-01-01

    Cue modulation of the startle reflex is a paradigm that has been used to understand the emotional mechanisms involved in alcohol dependence. Attenuation of the startle reflex has been demonstrated when alcohol-dependent subjects are exposed to alcohol-related stimuli. However, the role of clinical variables on the magnitude of this response is unknown. The objective of this study was to determine the relationship between a number of clinical variables-severity of alcoholism, family history of alcoholism (FHA+), personality traits related to the sensitivity to reward-and the startle reflex response when subjects with alcohol dependence were viewing alcohol-related cues. After detoxification, 98 participants completed self-report instruments and had eye blink electromyograms measured to acoustic startle probes [100-millisecond burst of white noise at 95 dB(A)] while viewing alcohol-related pictures, and standardised appetitive, aversive and neutral control scenes. Ninety-eight healthy controls were also assessed with the same instruments. There were significant differences on alcohol-startle magnitude between patients and controls. Comparisons by gender showed that women perceived alcohol cues and appetitive cues more appetitive than men. Male and female patients showed more appetitive responses to alcohol cues when compared with their respective controls. Our patients showed an appetitive effect of alcohol cues that was positively related to severity of alcohol dependence, sensitivity to reward and a FHA+. The data confirmed that the pattern of the modulation of the acoustic startle reflex reveals appetitive effects of the alcohol cues and extended it to a variety of clinical variables.

  3. Effects of specimen resonances on acoustic-ultrasonic testing

    NASA Technical Reports Server (NTRS)

    Williams, J. H., Jr.; Kahn, E. B.; Lee, S. S.

    1983-01-01

    The effects of specimen resonances on acoustic ultrasonic (AU) nondestructive testing were investigated. Selected resonant frequencies and the corresponding normal mode nodal patterns of the aluminum block are measured up to 75.64 kHz. Prominent peaks in the pencil lead fracture and sphere impact spectra from the two transducer locations corresponded exactly to resonant frequencies of the block. It is established that the resonant frequencies of the block dominated the spectral content of the output signal. The spectral content of the output signals is further influenced by the transducer location relative to the resonant frequency nodal lines. Implications of the results are discussed in relation to AU parameters and measurements.

  4. Probing Prejudice with Startle Eyeblink Modification: A Marker of Attention, Emotion, or Both?

    PubMed Central

    Vanman, Eric J.; Ryan, John P.; Pedersen, William C.; Ito, Tiffany A.

    2015-01-01

    In social neuroscience research, startle eyeblink modification can serve as a marker of emotion, but it is less clear whether it can also serve as a marker of prejudice. In Experiment 1, 30 White students viewed photographs of White and Black targets while the startle eyeblink reflex and facial EMG from the brow and cheek regions were recorded. Prejudice was related to facial EMG activity, but not to startle modification, which instead appeared to index attention to race. To test further whether racial categorizations are associated with differential attention, a dual-task paradigm was used in Experiment 2. Fifty-four White and fifty-five Black participants responded more slowly to a tone presented when viewing a racial outgroup member or a negative stimulus, indicating that both draw more attention than ingroup members or positive stimuli. We conclude that startle modification is useful to index differential attention to groups when intergroup threat is low. PMID:26023325

  5. Acoustic emission testing of composite vessels under sustained loading

    NASA Technical Reports Server (NTRS)

    Lark, R. F.; Moorhead, P. E.

    1978-01-01

    Acoustic emissions (AE) generated from Kevlar 49/epoxy composite pressure vessels subjected to sustained load-to-failure tests were studied. Data from two different transducer locations on the vessels were compared. It was found that AE from vessel wall-mounted transducers showed a wide variance from those for identical vessels subjected to the same pressure loading. Emissions from boss-mounted transducers did, however, yield values that were relatively consistent. It appears that the signals from the boss-mounted transducers represent an integrated average of the emissions generated by fibers fracturing during the vessel tests. The AE from boss-mounted transducers were also independent of time for vessel failure. This suggests that a similar number of fiber fractures must occur prior to initiation of vessel failure. These studies indicate a potential for developing an AE test procedure for predicting the residual service life or integrity of composite vessels.

  6. Design and fabrication of an augmentor wing model for acoustic tests

    NASA Technical Reports Server (NTRS)

    Jackson, J.; Schedin, R. W.; Campbell, J. M.

    1973-01-01

    The design and fabrication of a full-scale section of an augmentor wing to be used for acoustic testing at the Lewis Research Center are discussed. This hardware will be used primarily to investigate scaling effects of acoustic data obtained during the Boeing-run model tests. Typical model test data is shown in the report, together with predictions on both performance and acoustics that can be expected from the full-scale section to be built. Areas covered include: the aerodynamic and acoustic criteria of the flap system and nozzles, detailed discussion of the hardware, test system operation procedure, and stress analysis of the entire test system.

  7. Acoustic and Thermal Testing of an Integrated Multilayer Insulation and Broad Area Cooling Shield System

    NASA Technical Reports Server (NTRS)

    Wood, Jessica J.; Foster, Lee W.

    2013-01-01

    A Multilayer Insulation (MLI) and Broad Area Cooling (BAC) shield thermal control system shows promise for long-duration storage of cryogenic propellant. The NASA Cryogenic Propellant Storage and Transfer (CPST) project is investigating the thermal and structural performance of this tank-applied integrated system. The MLI/BAC Shield Acoustic and Thermal Test was performed to evaluate the MLI/BAC shield's structural performance by subjecting it to worst-case launch acoustic loads. Identical thermal tests using Liquid Nitrogen (LN2) were performed before and after the acoustic test. The data from these tests was compared to determine if any degradation occurred in the thermal performance of the system as a result of exposure to the acoustic loads. The thermal test series consisted of two primary components: a passive boil-off test to evaluate the MLI performance and an active cooling test to evaluate the integrated MLI/BAC shield system with chilled vapor circulating through the BAC shield tubes. The acoustic test used loads closely matching the worst-case envelope of all launch vehicles currently under consideration for CPST. Acoustic test results yielded reasonable responses for the given load. The thermal test matrix was completed prior to the acoustic test and successfully repeated after the acoustic test. Data was compared and yielded near identical results, indicating that the MLI/BAC shield configuration tested in this series is an option for structurally implementing this thermal control system concept.

  8. A cost minimisation and Bayesian inference model predicts startle reflex modulation across species.

    PubMed

    Bach, Dominik R

    2015-04-07

    In many species, rapid defensive reflexes are paramount to escaping acute danger. These reflexes are modulated by the state of the environment. This is exemplified in fear-potentiated startle, a more vigorous startle response during conditioned anticipation of an unrelated threatening event. Extant explanations of this phenomenon build on descriptive models of underlying psychological states, or neural processes. Yet, they fail to predict invigorated startle during reward anticipation and instructed attention, and do not explain why startle reflex modulation evolved. Here, we fill this lacuna by developing a normative cost minimisation model based on Bayesian optimality principles. This model predicts the observed pattern of startle modification by rewards, punishments, instructed attention, and several other states. Moreover, the mathematical formalism furnishes predictions that can be tested experimentally. Comparing the model with existing data suggests a specific neural implementation of the underlying computations which yields close approximations to the optimal solution under most circumstances. This analysis puts startle modification into the framework of Bayesian decision theory and predictive coding, and illustrates the importance of an adaptive perspective to interpret defensive behaviour across species.

  9. Acoustic emission monitoring of HFIR vessel during hydrostatic testing. Final report

    SciTech Connect

    Friesel, M.A.; Dawson, J.F.

    1992-08-01

    This report discusses the results and conclusions reached from applying acoustic emission monitoring to surveillance of the High Flux Isotope Reactor vessel during pressure testing. The objective of the monitoring was to detect crack growth and/or fluid leakage should it occur during the pressure test. The report addresses the approach, acoustic emission instrumentation, installation, calibration, and test results.

  10. Acoustic and microwave tests in a cylindrical cavity for acoustic gas thermometry at high temperature

    PubMed Central

    Zhang, K.; Feng, X.J.; Gillis, K.; Moldover, M.; Zhang, J.T.; Lin, H.; Qu, J.F.; Duan, Y.N.

    2016-01-01

    Relative primary acoustic gas thermometry determines the ratios of thermodynamic temperatures from measured ratios of acoustic and microwave resonance frequencies in a gas-filled metal cavity on isotherms of interest. When measured in a cavity with known dimensions, the frequencies of acoustic resonances in a gas determine the speed of sound, which is a known function of the thermodynamic temperature T. Changes in the dimensions of the cavity are measured using the frequencies of the cavity's microwave resonances. We explored techniques and materials for acoustic gas thermometry at high temperatures using a cylindrical cavity with remote acoustic transducers. We used gas-filled ducts as acoustic waveguides to transmit sound between the cavity at high temperatures and the acoustic transducers at room temperature. We measured non-degenerate acoustic modes in a cylindrical cavity in the range 295 K < T < 797 K. The fractional uncertainty of the measured acoustic frequencies increased from 2×10−6 at 295 K to 5×10−6 at 797 K. In addition, we measured the frequencies of several transverse magnetic (TM) microwave resonances up to 1000 K in order to track changes in the cavity's length L and radius R. The fractional standard deviation of the values of L deduced from three TM modes increased from 3×10−6 for T < 600 K to 57×10−6 at 1000 K. We observed similar inconsistencies in a previous study. PMID:26903106

  11. Measurement of transmission loss characteristics using acoustic intensity techniques at the KU-FRL Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Roskam, J.

    1983-01-01

    The transmission loss characteristics of panels using the acoustic intensity technique is presented. The theoretical formulation, installation of hardware, modifications to the test facility, and development of computer programs and test procedures are described. A listing of all the programs is also provided. The initial test results indicate that the acoustic intensity technique is easily adapted to measure transmission loss characteristics of panels. Use of this method will give average transmission loss values. The fixtures developed to position the microphones along the grid points are very useful in plotting the intensity maps of vibrating panels.

  12. Peritraumatic startle response predicts the vulnerability to develop PTSD-like behaviors in rats: a model for peritraumatic dissociation.

    PubMed

    Dong, Xinwen; Li, Yonghui

    2014-01-01

    Peritraumatic dissociation, a state characterized by alteration in perception and reduced awareness of surroundings, is considered to be a risk factor for the development of post-traumatic stress disorder (PTSD). However, the predictive ability of peritraumatic dissociation is questioned for the inconsistent results in different time points of assessment. The startle reflex is an objective behavioral measurement of defensive response to abrupt and intense sensory stimulus of surroundings, with potential to be used as an assessment on the dissociative status in both humans and rodents. The present study examined the predictive effect of acoustic startle response (ASR) in different time points around the traumatic event in an animal model of PTSD. The PTSD-like symptoms, including hyperarousal, avoidance, and contextual fear, were assessed 2-3 weeks post-trauma. The results showed that (1) the startle amplitude attenuated immediate after intense footshock in almost half of the stress animals, and (2) the attenuated startle responses at 1 h but not 24 h after stress predicted the development of severe PTSD-like symptoms. These data indicate that the startle alteration at the immediate period after trauma, including 1 h, is more important in PTSD prediction than 24 h after trauma. Our study also suggests that the startle attenuation immediate after intense stress may serve as an objective measurement of peritraumatic dissociation in rats.

  13. Developmental investigation of fear-potentiated startle across puberty.

    PubMed

    Schmitz, Anja; Grillon, Christian; Avenevoli, Shelli; Cui, Lihong; Merikangas, Kathleen R

    2014-03-01

    The goal of this study was to examine the association between affective development, puberty, and gender using the startle reflex as a marker of defensive mechanisms. Thirty-one male and thirty-five female adolescents aged ten to thirteen participated in a prospective study with up to five assessments. Longitudinal analyses revealed a significant effect of sex, with girls showing stronger fear-potentiation at all pubertal stages. Post hoc tests revealed that fear-potentiation increased in girls but not boys over the course of puberty. Furthermore, baseline startle decreased over the course of puberty. Because age was included as a covariate in all analyses, the puberty effect cannot be accounted for by age. To the best of our knowledge, this study provides the first evidence for a significant increase in fear-potentiated startle across the pubertal transition. Attribution of these changes to pubertal status rather than age has important implications for our understanding of the neurobiology of anxiety and affect regulation.

  14. NASA Rat Acoustic Tolerance Test 1994-1995

    NASA Technical Reports Server (NTRS)

    Holley, Daniel C.; Mele, Gary D.; Naidu, Sujata

    1996-01-01

    The major objective of this Cooperative Agreement was to develop a noise level specification for laboratory rats in the Centrifuge Facility Specimen Chambers (Space Station Biological Research Project), and to validate the specification for 3 noise octave bands: center frequencies 8 kHz, 16, kHz, and 32 kHz. This has been accomplished. Objective measures were used to verify that the chronic noise exposure was not harmful to the animals from physiological and behavioral perspectives. These measures were defined in the Stress Assessment Battery Validation for the Rat Acoustic Tolerance Test. In addition, the effects of the chronic noise exposure on rat hearing was assessed by the Brainstem Auditory Evoked Potential Method (BAER).

  15. Ares I Scale Model Acoustic Test Overpressure Results

    NASA Technical Reports Server (NTRS)

    Casiano, M. J.; Alvord, D. A.; McDaniels, D. M.

    2011-01-01

    A summary of the overpressure environment from the 5% Ares I Scale Model Acoustic Test (ASMAT) and the implications to the full-scale Ares I are presented in this Technical Memorandum. These include the scaled environment that would be used for assessing the full-scale Ares I configuration, observations, and team recommendations. The ignition transient is first characterized and described, the overpressure suppression system configuration is then examined, and the final environment characteristics are detailed. The recommendation for Ares I is to keep the space shuttle heritage ignition overpressure (IOP) suppression system (below-deck IOP water in the launch mount and mobile launcher and also the crest water on the main flame deflector) and the water bags.

  16. Direct-field acoustic testing of a flight system : logistics, challenges, and results.

    SciTech Connect

    Stasiunas, Eric Carl; Gurule, David Joseph; Babuska, Vit; Skousen, Troy J.

    2010-10-01

    Before a spacecraft can be considered for launch, it must first survive environmental testing that simulates the launch environment. Typically, these simulations include vibration testing performed using an electro-dynamic shaker. For some spacecraft however, acoustic excitation may provide a more severe loading environment than base shaker excitation. Because this was the case for a Sandia Flight System, it was necessary to perform an acoustic test prior to launch in order to verify survival due to an acoustic environment. Typically, acoustic tests are performed in acoustic chambers, but because of scheduling, transportation, and cleanliness concerns, this was not possible. Instead, the test was performed as a direct field acoustic test (DFAT). This type of test consists of surrounding a test article with a wall of speakers and controlling the acoustic input using control microphones placed around the test item, with a closed-loop control system. Obtaining the desired acoustic input environment - proto-flight random noise input with an overall sound pressure level (OASPL) of 146.7 dB-with this technique presented a challenge due to several factors. An acoustic profile with this high OASPL had not knowingly been obtained using the DFAT technique prior to this test. In addition, the test was performed in a high-bay, where floor space and existing equipment constrained the speaker circle diameter. And finally, the Flight System had to be tested without contamination of the unit, which required a contamination bag enclosure of the test unit. This paper describes in detail the logistics, challenges, and results encountered while performing a high-OASPL, direct-field acoustic test on a contamination-sensitive Flight System in a high-bay environment.

  17. Acoustic Performance of Drive Rig Mufflers for Model Scale Engine Testing

    NASA Technical Reports Server (NTRS)

    Stephens, David, B.

    2013-01-01

    Aircraft engine component testing at the NASA Glenn Research Center (GRC) includes acoustic testing of scale model fans and propellers in the 9- by15-Foot Low Speed Wind Tunnel (LSWT). This testing utilizes air driven turbines to deliver power to the article being studied. These air turbines exhaust directly downstream of the model in the wind tunnel test section and have been found to produce significant unwanted noise that reduces the quality of the acoustic measurements of the engine model being tested. This report describes an acoustic test of a muffler designed to mitigate the extraneous turbine noise. The muffler was found to provide acoustic attenuation of at least 8 dB between 700 Hz and 20 kHz which significantly improves the quality of acoustic measurements in the facility.

  18. Measurement resolution of noise directivity patterns from acoustic flight tests

    NASA Technical Reports Server (NTRS)

    Conner, David A.

    1989-01-01

    The measurement resolution of noise directivity patterns from acoustic flight tests was investigated. Directivity angle resolution is affected by the data reduction parameters, the aircraft velocity and flyover altitude, and by deviations of the aircraft from the desired flight path. Equations are developed which determine bounds for the lateral and longitudinal directivity angle resolution as a function of the nominal directivity angle. The equations are applied to a flight test data base and the effects of several flight conditions and data reduction parameters on the directivity angle resolution are presented. The maximum directivity angle resolution typically occurs when the aircraft is at or near the overhead position. In general, directivity angle resolution improves with decreasing velocity, increasing altitude, increasing sampling rate, decreasing block size, and decreasing block averages. Deviations from the desired ideal flight path will increase the resolution. For the flight experiment considered in this study, an average of two flyovers were required at each test condition to obtain an acceptable flight path. The ability of the pilot to maintain the flight track improved with decreasing altitude, decreasing velocity, and practice. Due to the prevailing wind conditions, yaw angles of as much as 20 deg were required to maintain the desired flight path.

  19. Numerical simulation of the tip aerodynamics and acoustics test

    NASA Astrophysics Data System (ADS)

    Tejero E, F.; Doerffer, P.; Szulc, O.; Cross, J. L.

    2016-04-01

    The application of an efficient flow control system on helicopter rotor blades may lead to improved aerodynamic performance. Recently, our invention of Rod Vortex Generators (RVGs) has been analyzed for helicopter rotor blades in hover with success. As a step forward, the study has been extended to forward flight conditions. For this reason, a validation of the numerical modelling for a reference helicopter rotor (without flow control) is needed. The article presents a study of the flow-field of the AH-1G helicopter rotor in low-, medium- and high-speed forward flight. The CFD code FLOWer from DLR has proven to be a suitable tool for the aerodynamic analysis of the two-bladed rotor without any artificial wake modelling. It solves the URANS equations with LEA (Linear Explicit Algebraic stress) k-ω model using the chimera overlapping grids technique. Validation of the numerical model uses comparison with the detailed flight test data gathered by Cross J. L. and Watts M. E. during the Tip Aerodynamics and Acoustics Test (TAAT) conducted at NASA in 1981. Satisfactory agreements for all speed regimes and a presence of significant flow separation in high-speed forward flight suggest a possible benefit from the future implementation of RVGs. The numerical results based on the URANS approach are presented not only for a popular, low-speed case commonly used in rotorcraft community for CFD codes validation but preferably for medium- and high-speed test conditions that have not been published to date.

  20. The Ability to Structure Acoustic Material as a Measure of Musical Aptitude. 4. Experiences with Modifications of the Acoustic Structuring Test. Research Bulletin. No. 51.

    ERIC Educational Resources Information Center

    Karma, Kai

    Four new versions of an acoustic structuring test were developed, administered, and analyzed in order to produce better tests and to contribute to better understanding of the abilities measured by these tests. The tests consist of tape recordings of patterns of musical notes played on an electric organ or an acoustic guitar. Item analyses and…

  1. Decreased startle modulation during anticipation in the postpartum period in comparison to late pregnancy.

    PubMed

    Hellgren, Charlotte; Bannbers, Elin; Åkerud, Helena; Risbrough, Victoria; Poromaa, Inger Sundström

    2012-04-01

    Knowledge about healthy women’s psychophysiological adaptations during the large neuroendocrine changes of pregnancy and childbirth is essential in order to understand why these events have the potential to disrupt mental health in vulnerable individuals. This study aimed to compare startle response modulation, an objective psychophysiological measure demonstrated to be influenced by anxiety and depression, longitudinally across late pregnancy and the postpartum period. The acoustic startle response modulation was assessed during anticipation of affective images and during image viewing in 31 healthy women during gestational weeks 36–39 and again at 4 to 6 weeks postpartum. No startle modulation by affective images was observed at either time point. Significant modulation during anticipation stimuli was found at pregnancy assessment but was reduced in the postpartum period. The women rated the unpleasant images more negative and more arousing and the pleasant images more positive at the postpartum assessment. Self-reported anxiety and depressive symptoms did not change between assessments. The observed postpartum decrease in modulation of startle by anticipation suggests a relatively deactivated defense system in the postpartum period.

  2. Intermedius nerve involvement and testing in acoustic neuromas.

    PubMed

    Thomsen, J; Zilstorff, K

    1975-01-01

    The clinical findings in 125 patients with surgically confirmed acoustic neuromas are presented, with special regard to the involvement of the intermedius nerve in the diagnosis. In assessing the function of the intermedius nerve the examination of the nasolacrimal reflex and the sensation of taste on the anterior two-thirds of the tongue are used. The methods of investigation are described in detail. The material consisted of 20 medium-sized and 105 large tumours; no intracanalicular tumor was found. Hearing loss was the initial symptom in 85% of the patients, 10% had tinitus and 4% vertigo as the first symptom. Apart from the VIII cranial nerve symptoms, a defective nasolacrimal reflex was the most significant evidence of cerebellopontine angle pathology. The test was positive in 65% of the medium-sized tumours, in the entire material, 85%. The figures are higher than the incidence of trigeminal nerve symptoms. This in contrast to the reports of most authors. The tests described are simple and quick to perform, and it is emphasized that they should be applied to all patients with unilateral hearing loss of unknown origin.

  3. Acoustic Quality of the 40- by 80- Foot Wind Tunnel Test Section After Installation of a Deep Acoustic Lining

    NASA Technical Reports Server (NTRS)

    Soderman, Paul T.; Jaeger, Stephen M.; Hayes, Julie A.; Allen, Christopher S.

    2002-01-01

    A recessed, 42-inch deep acoustic lining has been designed and installed in the 40- by 80- Foot Wind Tunnel (40x80) test section to greatly improve the acoustic quality of the facility. This report describes the test section acoustic performance as determined by a detailed static calibration-all data were acquired without wind. Global measurements of sound decay from steady noise sources showed that the facility is suitable for acoustic studies of jet noise or similar randomly generated sound. The wall sound absorption, size of the facility, and averaging effects of wide band random noise all tend to minimize interference effects from wall reflections. The decay of white noise with distance was close to free field above 250 Hz. However, tonal sound data from propellers and fans, for example, will have an error band to be described that is caused by the sensitivity of tones to even weak interference. That error band could be minimized by use of directional instruments such as phased microphone arrays. Above 10 kHz, air absorption began to dominate the sound field in the large test section, reflections became weaker, and the test section tended toward an anechoic environment as frequency increased.

  4. Payload bay atmospheric vent airflow testing at the Vibration and Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    Johnston, James D., Jr.

    1988-01-01

    Several concerns related to venting the Space Shuttle Orbiter payload bay during launch led to laboratory experiments with a flight-type vent box installed in the wall of a subsonic wind tunnel. This report describes the test setups and procedures used to acquire data for characterization of airflow through the vent box and acoustic tones radiated from the vent-box cavity. A flexible boundary-layer spoiler which reduced the vent-tone amplitude is described.

  5. Hypnotizability, Hypnosis and Prepulse Inhibition of the Startle Reflex in Healthy Women: An ERP Analysis

    PubMed Central

    De Pascalis, Vilfredo; Russo, Emanuela

    2013-01-01

    A working model of the neurophysiology of hypnosis suggests that highly hypnotizable individuals (HHs) have more effective frontal attentional systems implementing control, monitoring performance, and inhibiting unwanted stimuli from conscious awareness, than low hypnotizable individuals (LHs). Recent studies, using prepulse inhibition (PPI) of the auditory startle reflex (ASR), suggest that HHs, in the waking condition, may show reduced sensory gating although they may selectively attend and disattend different stimuli. Using a within subject design and a strict subject selection procedure, in waking and hypnosis conditions we tested whether HHs compared to LHs showed a significantly lower inhibition of the ASR and startle-related brain activity in both time and intracerebral source localization domains. HHs, as compared to LH participants, exhibited (a) longer latency of the eyeblink startle reflex, (b) reduced N100 responses to startle stimuli, and (c) higher PPI of eyeblink startle and of the P200 and P300 waves. Hypnosis yielded smaller N100 waves to startle stimuli and greater PPI of this component than in the waking condition. sLORETA analysis revealed that, for the N100 (107 msec) elicited during startle trials, HHs had a smaller activation in the left parietal lobe (BA2/40) than LHs. Auditory pulses of pulse-with prepulse trials in HHs yielded less activity of the P300 (280 msec) wave than LHs, in the cingulate and posterior cingulate gyrus (BA23/31). The present results, on the whole, are in the opposite direction to PPI findings on hypnotizability previously reported in the literature. These results provide support to the neuropsychophysiological model that HHs have more effective sensory integration and gating (or filtering) of irrelevant stimuli than LHs. PMID:24278150

  6. NASA LeRC's Acoustic Fill Effect Test Program and Results

    NASA Technical Reports Server (NTRS)

    Hughes, William O.; Mcnelis, Mark E.; Manning, Jerome E.

    1994-01-01

    NASA Lewis Research Center, in conjunction with General Dynamics Space Systems Division, has performed a test program to investigate the acoustic fill effect for an unblanketed payload fairing for a variety of payload simulators. This paper will discuss this test program and fill factor test data, and make comparisons with theoretical predictions. This paper will also address the NASA acoustic fill effect standard which was verified from the test data analysis.

  7. Startle reflex hyporeactivity in Parkinson's disease: an emotion-specific or arousal-modulated deficit?

    PubMed Central

    Miller, K.M.; Okun, M.S.; Marsiske, M.; Fennell, E.B.; Bowers, D.

    2009-01-01

    We previously reported that patients with Parkinson's disease (PD) demonstrate reduced psychophysiologic reactivity to unpleasant pictures as indexed by diminished startle eyeblink magnitude (Bowers et al., 2006). In the present study, we tested the hypothesis that this hyporeactivity was primarily driven by diminished reactivity to fear-eliciting stimuli as opposed to other types of aversive pictures. This hypothesis was based on previous evidence suggesting amygdalar abnormalities in PD patients coupled with the known role of the amygdala in fear processing. To test this hypothesis, 24 patients with Parkinson's disease and 24 controls viewed standardized sets of emotional pictures that depicted fear, disgust (mutilations, contaminations), pleasant, and neutral contents. Startle eyeblinks were elicited while subjects viewed these emotional pictures. Results did not support the hypothesis of a specific deficit to fear pictures. Instead, the PD patients had reduced reactivity to mutilation pictures relative to other types of negative pictures in the context of normal subjective ratings. Further analyses revealed that controls displayed a pattern of increased startle eyeblink magnitude for “high arousal” versus “low arousal” negative pictures, regardless of picture category, whereas startle eyeblink magnitude in the PD group did not vary by arousal level. These results suggest that previous findings of decreased aversion-modulated startle is driven by reduced reactivity to highly arousing negative stimuli rather than to a specific category (i.e., fear or disgust) of emotion stimuli. PMID:19428424

  8. Gender difference in speech intelligibility using speech intelligibility tests and acoustic analyses

    PubMed Central

    2010-01-01

    PURPOSE The purpose of this study was to compare men with women in terms of speech intelligibility, to investigate the validity of objective acoustic parameters related with speech intelligibility, and to try to set up the standard data for the future study in various field in prosthodontics. MATERIALS AND METHODS Twenty men and women were served as subjects in the present study. After recording of sample sounds, speech intelligibility tests by three speech pathologists and acoustic analyses were performed. Comparison of the speech intelligibility test scores and acoustic parameters such as fundamental frequency, fundamental frequency range, formant frequency, formant ranges, vowel working space area, and vowel dispersion were done between men and women. In addition, the correlations between the speech intelligibility values and acoustic variables were analyzed. RESULTS Women showed significantly higher speech intelligibility scores than men and there were significant difference between men and women in most of acoustic parameters used in the present study. However, the correlations between the speech intelligibility scores and acoustic parameters were low. CONCLUSION Speech intelligibility test and acoustic parameters used in the present study were effective in differentiating male voice from female voice and their values might be used in the future studies related patients involved with maxillofacial prosthodontics. However, further studies are needed on the correlation between speech intelligibility tests and objective acoustic parameters. PMID:21165272

  9. Acoustic emission analysis as a non-destructive test procedure for fiber compound structures

    NASA Technical Reports Server (NTRS)

    Block, J.

    1983-01-01

    The concept of acoustic emission analysis is explained in scientific terms. The detection of acoustic events, their localization, damage discrimination, and event summation curves are discussed. A block diagram of the concept of damage-free testing of fiber-reinforced synthetic materials is depicted. Prospects for application of the concept are assessed.

  10. Development of an Acoustic Impedance Tube Testbed for Material Sample Testing

    NASA Technical Reports Server (NTRS)

    Doty, Benjamin J.; Kolaini, Ali R.

    2012-01-01

    Acoustic impedance tube method: uses Traveling wave amplitudes are measured on either side of a sample in a tube. Many acoustic properties of the sample can be calculated. It is Simple and inexpensive to set up, ideal for high volume optimization tests

  11. Titanium honeycomb acoustic lining structural and thermal test report. [for acoustic tailpipe for JT8D engine

    NASA Technical Reports Server (NTRS)

    Joynes, D.; Balut, J. P.

    1974-01-01

    The results are presented of static, fatigue and thermal testing of titanium honeycomb acoustic panels representing the acoustic tailpipe for the Pratt and Whitney Aircraft JT8D Refan engine which is being studied for use on the Boeing 727-200 airplane. Test specimens represented the engine and tailpipe flange joints, the rail to which the thrust reverser is attached and shear specimens of the tailpipe honeycomb. Specimens were made in four different batches with variations in configuration, materials and processes in each. Static strength of all test specimens exceeded the design ultimate load requirements. Fatigue test results confirmed that aluminum brazed titanium, as used in the Refan tailpipe design, meets the fatigue durability objectives. Quality of welding was found to be critical to life, with substandard welding failing prematurely, whereas welding within the process specification exceeded the panel skin life. Initial fatigue testing used short grip length bolts which failed prematurely. These were replaced with longer bolts and subsequent testing demonstrated the required life. Thermal tests indicate that perforated skin acoustic honeycomb has approximately twice the heat transfer of solid skin honeycomb.

  12. Validation and Simulation of ARES I Scale Model Acoustic Test -1- Pathfinder Development

    NASA Technical Reports Server (NTRS)

    Putnam, G. C.

    2011-01-01

    The Ares I Scale Model Acoustics Test (ASMAT) is a series of live-fire tests of scaled rocket motors meant to simulate the conditions of the Ares I launch configuration. These tests have provided a well documented set of high fidelity measurements useful for validation including data taken over a range of test conditions and containing phenomena like Ignition Over-Pressure and water suppression of acoustics. To take advantage of this data, a digital representation of the ASMAT test setup has been constructed and test firings of the motor have been simulated using the Loci/CHEM computational fluid dynamics software. Within this first of a series of papers, results from ASMAT simulations with the rocket in a held down configuration and without water suppression have then been compared to acoustic data collected from similar live-fire tests to assess the accuracy of the simulations. Detailed evaluations of the mesh features, mesh length scales relative to acoustic signals, Courant-Friedrichs-Lewy numbers, and spatial residual sources have been performed to support this assessment. Results of acoustic comparisons have shown good correlation with the amplitude and temporal shape of pressure features and reasonable spectral accuracy up to approximately 1000 Hz. Major plume and acoustic features have been well captured including the plume shock structure, the igniter pulse transient, and the ignition overpressure. Finally, acoustic propagation patterns illustrated a previously unconsidered issue of tower placement inline with the high intensity overpressure propagation path.

  13. A wireless data acquisition system for acoustic emission testing

    NASA Astrophysics Data System (ADS)

    Zimmerman, A. T.; Lynch, J. P.

    2013-01-01

    As structural health monitoring (SHM) systems have seen increased demand due to lower costs and greater capabilities, wireless technologies have emerged that enable the dense distribution of transducers and the distributed processing of sensor data. In parallel, ultrasonic techniques such as acoustic emission (AE) testing have become increasingly popular in the non-destructive evaluation of materials and structures. These techniques, which involve the analysis of frequency content between 1 kHz and 1 MHz, have proven effective in detecting the onset of cracking and other early-stage failure in active structures such as airplanes in flight. However, these techniques typically involve the use of expensive and bulky monitoring equipment capable of accurately sensing AE signals at sampling rates greater than 1 million samples per second. In this paper, a wireless data acquisition system is presented that is capable of collecting, storing, and processing AE data at rates of up to 20 MHz. Processed results can then be wirelessly transmitted in real-time, creating a system that enables the use of ultrasonic techniques in large-scale SHM systems.

  14. The effects of startle and non-startle auditory stimuli on wrist flexion movement in Parkinson's disease.

    PubMed

    Fernandez-Del-Olmo, Miguel; Bello, Olalla; Lopez-Alonso, Virginia; Marquez, G; Sanchez, Jose A; Morenilla, Luis; Valls-Solé, Josep

    2013-08-26

    Startle stimuli lead to shorter reaction times in control subjects and Parkinson's disease (PD) patients. However, non-startle stimuli also enhance movement initiation in PD. We wanted to examine whether a startle-triggered movement would retain similar kinematic and EMG-related characteristics compared to one induced by a non-startle external cue in PD patients. In this study we investigated the electromyography pattern and the reaction time during a wrist flexion movement in response to three different stimuli: a visual imperative stimulus; visual stimulus simultaneous with a non-startle auditory stimulus and with a startle auditory stimulus. Ten PD patients and ten aged matched controls participated in this study. The reaction times were faster for startle and non-startle stimuli in comparison with the visual imperative stimulus, in both patients and control subjects. The startle cue induced a faster reaction than the non-startle cue. The electromyography pattern remained unchanged across the conditions. The results suggest that the startle reaction effect for upper limb movements are unimpaired in PD patients and has different characteristics than the effect of non-startle stimuli.

  15. 21 CFR 874.1060 - Acoustic chamber for audiometric testing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Diagnostic Devices § 874.1060 Acoustic chamber for... provides isolation from outside sounds. (b) Classification. Class I (general controls). The device...

  16. 21 CFR 874.1060 - Acoustic chamber for audiometric testing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Diagnostic Devices § 874.1060 Acoustic chamber for... provides isolation from outside sounds. (b) Classification. Class I (general controls). The device...

  17. Distinct Contributions of Median Raphe Nucleus to Contextual Fear Conditioning and Fear-Potentiated Startle

    PubMed Central

    Silva, R. C. B.; Cruz, A. P. M.; Avanzi, V.; Landeira-Fernandez, J.; Brandão, M. L.

    2002-01-01

    Ascending 5-HT projections from the median raphe nucleus (MRN), probably to the hippocampus, are implicated in the acquisition of contextual fear (background stimuli), as assessed by freezing behavior. Foreground cues like light, used as a conditioned stimulus (CS) in classical fear conditioning, also cause freezing through thalamic transmission to the amygdala. As the MRN projects to the hippocampus and amygdala, the role of this raphe nucleus in fear conditioning to explicit cues remains to be explained. Here we analyzed the behavior of rats with MRN electrolytic lesions in a contextual conditioning situation and in a fear-potentiated startle procedure. The animals received MRN electrolytic lesions either before or on the day after two consecutive training sessions in which they were submitted to 10 conditioning trials, each in an experimental chamber (same context) where they. received foot-shocks (0.6 mA, 1 sec) paired to a 4-sec light CS. Seven to ten days later, the animals were submitted to testing sessions for assessing conditioned fear when they were placed for five shocks, and the duration of contextual freezing was recorded. The animals were then submitted to a fear-potentiated startle in response to a 4-sec light-CS, followed by white noise (100 dB, 50 ms). Control rats (sham) tested in the same context showed more freezing than did rats with pre- or post-training MRN lesions. Startle was clearly potentiated in the presence of light CS in the sham-lesioned animals. Whereas pretraining lesions reduced both freezing and fear-potentiated startle, the post-training lesions reduced only freezing to context, without changing the fear-potentiated startle. In a second experiment, neurotoxic lesions of the MRN with local injections of N-methyl-D-aspartate or the activation of 5-HT1A somatodendritic auto-receptors of the MRN by microinjections of the 5-HT1A receptor agonist 8-hydroxy- 2-(di-n-propylamino)tetralin (8-OH-DPAT) before the training sessions also

  18. High-intensity acoustic tests of a thermally stressed plate

    NASA Technical Reports Server (NTRS)

    Ng, Chung Fai; Clevenson, Sherman A.

    1991-01-01

    An investigation was conducted in the Thermal Acoustic Fatigue Apparatus at the Langley Research Center to study the acoustically excited random motion of an aluminum plate which is buckled due to thermal stresses. The thermal buckling displacements were measured and compared with theory. The general trends of the changes in resonances frequencies and random responses of the plate agree with previous theoretical prediction and experimental results for a mechanically buckled plate.

  19. Aerodynamic and acoustic test of a United Technologies model scale rotor at DNW

    NASA Technical Reports Server (NTRS)

    Yu, Yung H.; Liu, Sandy R.; Jordan, Dave E.; Landgrebe, Anton J.; Lorber, Peter F.; Pollack, Michael J.; Martin, Ruth M.

    1990-01-01

    The UTC model scale rotors, the DNW wind tunnel, the AFDD rotary wing test stand, the UTRC and AFDD aerodynamic and acoustic data acquisition systems, and the scope of test matrices are discussed and an introduction to the test results is provided. It is pointed out that a comprehensive aero/acoustic database of several configurations of the UTC scaled model rotor has been created. The data is expected to improve understanding of rotor aerodynamics, acoustics, and dynamics, and lead to enhanced analytical methodology and design capabilities for the next generation of rotorcraft.

  20. A closed-loop automatic control system for high-intensity acoustic test systems.

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1973-01-01

    Sound at sound pressure levels in the range from 130 to 160 dB is used in the investigation. Random noise is passed through a series of parallel filters, generally 1/3-octave wide. A basic automatic system is investigated because of preadjustment inaccuracies and high costs found in a study of a typical manually controlled acoustic testing system. The unit described has been successfully used in automatic acoustic tests in connection with the spacecraft tests for the Mariner 1971 program.

  1. Sea Test of a Parametric Acoustic Receiving Array at Stage I.

    DTIC Science & Technology

    1980-11-07

    SUPPLEMENTARY NOTES It. KEY WORDS (CoathwRae on reverse side iI necessary and Identify by block inmber) PARRAY Nonlinear acoustics Sea test...Austin, has been engaged in a program to develop an experimental parametric acoustic receiving array ( PARRAY ). A sea test was performed in shallow...FIGURES v LIST OF TABLES vii 1. INTRODUCTION 1 II. SEA TEST OBJECTIVES 5 III. EXPERIMENTAL PARRAY DESCRIPTION AND INSTALLATION 7 A. System Hardware 7 B

  2. Wind Turbine Generator System Acoustic Noise Test Report for the ARE 442 Wind Turbine

    SciTech Connect

    Huskey, A.; van Dam, J.

    2010-11-01

    This test was conducted on the ARE 442 as part of the U.S. Department of Energy's (DOE's) Independent Testing project. This project was established to help reduce the barriers of wind energy expansion by providing independent testing results for small turbines. In total, five turbines are being tested at the National Wind Technology Center (NWTC) as a part of this project. Acoustic noise testing is one of up to five tests that may be performed on the turbines, including duration, safety and function, power performance, and power quality tests. The acoustic noise test was conducted to the IEC 61400-11 Edition 2.1.

  3. Instruction-dependent modulation of the long-latency stretch reflex is associated with indicators of startle

    PubMed Central

    Ravichandran, Vengateswaran J.; Honeycutt, Claire F.; Shemmell, Jonathan; Perreault, Eric J.

    2013-01-01

    Long-latency responses elicited by postural perturbation are modulated by how a subject is instructed to respond to the perturbation, yet the neural pathways responsible for this modulation remain unclear. The goal of this study was to determine if instruction-dependent modulation is associated with activity in brainstem pathways contributing to startle. Our hypothesis was that elbow perturbations can evoked startle, indicated by activity in the sternocleidomastoid muscle (SCM). Perturbation responses were compared to those elicited by a loud acoustic stimulus, known to elicit startle. Postural perturbations and startling acoustic stimuli both evoked SCM activity, but only when a ballistic elbow extension movement was planned. Both stimuli triggered SCM activity with the same probability. When SCM activity was present, there was an associated early onset of triceps EMG, as required for the planned movement. This early EMG onset occurred at a time often attributed to long-latency stretch reflexes (75-100ms). The nature of the perturbation-triggered EMG (excitatory or inhibitory) was independent of the perturbation direction (flexion or extension) indicating that it was not a feedback response appropriate for returning the limb to its original position. The net EMG response to perturbations delivered after a movement had been planned could be explained as the sum of a stretch reflex opposing the perturbation and a startle-evoked response associated with the prepared movement. These results demonstrate that rapid perturbations can trigger early release of a planned ballistic movement, and that this release is associated with activity in the brainstem pathways contributing to startle reflexes. PMID:23811739

  4. Laboratory test and acoustic analysis of cabin treatment for propfan test assessment aircraft

    NASA Technical Reports Server (NTRS)

    Kuntz, H. L.; Gatineau, R. J.

    1991-01-01

    An aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Helmholtz resonators were attached to the cabin trim panels to increase the sidewall transmission loss (TL). Resonators (448) were located between the trim panels and fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a 235 Hz resonance frequency. After flight testing on the PTA aircraft, the enclosure was tested in the Kelly Johnson R and D Center Acoustics Lab. Laboratory noise reduction (NR) test results are discussed. The enclosure was placed in a Gulfstream 2 fuselage section. Broadband (138 dB overall SPL) and tonal (149 dB overall SPL) excitations were used in the lab. Tonal excitation simulated the propfan flight test excitation. The fundamental tone was stepped in 2 Hz intervals from 225 through 245 Hz. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. The effects of flanking, sidewall absorption, cabin adsorption, resonator loading of trim panels, and panel vibrations are presented. Increases in NR of up to 11 dB were measured.

  5. Modulation of Prepulse Inhibition and Startle Reflex by Emotions: A Comparison between Young and Older Adults

    PubMed Central

    Le Duc, Jolyanne; Fournier, Philippe; Hébert, Sylvie

    2016-01-01

    This study examined whether or not the acoustic startle response and sensorimotor gating may be modulated by emotions differentially between young and older adults. Two groups of participants (mean age Young: 24 years old; Elderly: 63.6 years old) were presented with three types of auditory stimuli (Startle alone, High or Low frequency Prepulse) while viewing pleasant, neutral, or unpleasant images. Electromyographic activity of the eyeblink response was measured. Results show that older adults displayed diminished eyeblink responses whereas younger adults displayed enhanced eyeblink responses when viewing negative images. Sensorimotor gating also differed between young and older adults, with enhanced sensorimotor gating abilities while viewing positive pictures in older adults and diminished abilities while viewing negative pictures among younger adults. These results argue in favor of a differential emotional influence on the sensorimotor abilities of young and older adults, with a positivity bias among the latter. PMID:26941643

  6. Startle disease in Irish wolfhounds associated with a microdeletion in the glycine transporter GlyT2 gene

    PubMed Central

    Gill, Jennifer L.; Capper, Deborah; Vanbellinghen, Jean-François; Chung, Seo-Kyung; Higgins, Robert J.; Rees, Mark I.; Shelton, G. Diane; Harvey, Robert J.

    2011-01-01

    Defects in glycinergic synaptic transmission in humans, cattle, and rodents result in an exaggerated startle reflex and hypertonia in response to either acoustic or tactile stimuli. Molecular genetic studies have determined that mutations in the genes encoding the postsynaptic glycine receptor (GlyR) α1 and β subunits (GLRA1 and GLRB) and the presynaptic glycine transporter GlyT2 (SLC6A5) are the major cause of these disorders. Here, we report the first genetically confirmed canine cases of startle disease. A litter of seven Irish wolfhounds was identified in which two puppies developed muscle stiffness and tremor in response to handling. Although sequencing of GLRA1 and GLRB did not reveal any pathogenic mutations, analysis of SLC6A5 revealed a homozygous 4.2 kb microdeletion encompassing exons 2 and 3 in both affected animals. This results in the loss of part of the large cytoplasmic N-terminus and all subsequent transmembrane domains due to a frameshift. This genetic lesion was confirmed by defining the deletion breakpoint, Southern blotting, and multiplex ligation-dependent probe amplification (MLPA). This analysis enabled the development of a rapid genotyping test that revealed heterozygosity for the deletion in the dam and sire and three other siblings, confirming recessive inheritance. Wider testing of related animals has identified a total of 13 carriers of the SLC6A5 deletion as well as non-carrier animals. These findings will inform future breeding strategies and enable a rational pharmacotherapy of this new canine disorder. PMID:21420493

  7. NASA/GE quiet engine C acoustic test results

    NASA Technical Reports Server (NTRS)

    Kazin, S. B.; Pass, J. E.

    1974-01-01

    The acoustic investigation and evaluation of the C propulsion turbofan engine are discussed. The engine was built as a part of the Quiet Engine Program. The objectives of the program are as follows: (1) to determine the noise levels produced turbofan bypass engines, (2) to demonstrate the technology and innovations which will reduce the production and radiation of noise in turbofan engines, and (3) to acquire experimental acoustic and aerodynamic data for high bypass turbofan engines to provide a better understanding of noise production mechanisms. The goals of the program called for a turbofan engine 15 to 20 PNdB quieter than currently available engines in the same thrust class.

  8. On determining the acoustic properties of main helicopter rotor models on an open test bench

    NASA Astrophysics Data System (ADS)

    Kop'ev, V. F.; Zaitsev, M. Yu.; Ostrikov, N. N.; Denisov, S. L.; Makashov, S. Yu.; Anikin, V. A.; Gromov, V. V.

    2016-11-01

    The paper presents the results of experimental studies on developing a technique to determine the acoustic properties of models of main helicopter rotors on an open test bench. The method of maximum length sequences is used to choose the optimum arrangement of microphones for an open test bench that would minimize the influence of parasitic echo. The results of processing the data of an acoustic experiment with a model rotor are detailed.

  9. A Correlated Study of the Response of a Satellite to Acoustic Radiation Using Statistical Energy Analysis and Acoustic Test Data

    SciTech Connect

    CAP,JEROME S.; TRACEY,BRIAN

    1999-11-15

    Aerospace payloads, such as satellites, are subjected to vibroacoustic excitation during launch. Sandia's MTI satellite has recently been certified to this environment using a combination of base input random vibration and reverberant acoustic noise. The initial choices for the acoustic and random vibration test specifications were obtained from the launch vehicle Interface Control Document (ICD). In order to tailor the random vibration levels for the laboratory certification testing, it was necessary to determine whether vibration energy was flowing across the launch vehicle interface from the satellite to the launch vehicle or the other direction. For frequencies below 120 Hz this issue was addressed using response limiting techniques based on results from the Coupled Loads Analysis (CLA). However, since the CLA Finite Element Analysis FEA model was only correlated for frequencies below 120 Hz, Statistical Energy Analysis (SEA) was considered to be a better choice for predicting the direction of the energy flow for frequencies above 120 Hz. The existing SEA model of the launch vehicle had been developed using the VibroAcoustic Payload Environment Prediction System (VAPEPS) computer code [1]. Therefore, the satellite would have to be modeled using VAPEPS as well. As is the case for any computational model, the confidence in its predictive capability increases if one can correlate a sample prediction against experimental data. Fortunately, Sandia had the ideal data set for correlating an SEA model of the MTI satellite--the measured response of a realistic assembly to a reverberant acoustic test that was performed during MTI's qualification test series. The first part of this paper will briefly describe the VAPEPS modeling effort and present the results of the correlation study for the VAPEPS model. The second part of this paper will present the results from a study that used a commercial SEA software package [2] to study the effects of in-plane modes and to

  10. Maneuver Acoustic Flight Test of the Bell 430 Helicopter Data Report

    NASA Technical Reports Server (NTRS)

    Watts, Michael E.; Greenwood, Eric; Smith, Charles D.; Snider, Royce; Conner, David A.

    2014-01-01

    A cooperative ight test by NASA, Bell Helicopter and the U.S. Army to characterize the steady state acoustics and measure the maneuver noise of a Bell Helicopter 430 aircraft was accomplished. The test occurred during June/July 2011 at Eglin Air Force Base, Florida. This test gathered a total of 410 test points over 10 test days and compiled an extensive database of dynamic maneuver measurements. Three microphone arrays with up to 31 microphon. es in each were used to acquire acoustic data. Aircraft data included Differential Global Positioning System, aircraft state and rotor state information. This paper provides an overview of the test and documents the data acquired.

  11. Acoustic modelling and testing of diesel particulate filters

    NASA Astrophysics Data System (ADS)

    Allam, Sabry; Åbom, Mats

    2005-11-01

    The use of Diesel Particulate Filters (DPFs) on automobiles to reduce the harmful effects of diesel exhaust gases is becoming a standard in many countries. Although the main purpose of a DPF is to reduce harmful emission of soot particles it also affects the acoustic emission. This paper presents a first attempt to describe the acoustic behavior of DPFs and to present models which allow the acoustic two-port to be calculated. The simplest model neglects wave propagation and treats the filter as an equivalent acoustic resistance modeled via a lumped impedance element. This simple model gives a constant frequency-independent transmission loss and agrees within 1 dB with measured data on a typical filter (length 250 mm) up to 200-300 Hz (at 20 °C). In the second model, the ceramic filter monolith is described as a system of coupled porous channels carrying plane waves. The coupling between the channels through the porous walls is described via Darcy's law. This model gives a frequency-dependent transmission loss and agrees well with measured data in the entire plane wave range.

  12. A Brief Historical Survey of Rocket Testing Induced Acoustic Environments at NASA SSC

    NASA Technical Reports Server (NTRS)

    Allgood, Daniel C.

    2012-01-01

    A survey was conducted of all the various rocket test programs that have been performed since the establishment of NASA Stennis Space Center. The relevant information from each of these programs were compiled and used to quantify the theoretical noise source levels using the NASA approved methodology for computing "acoustic loads generated by a propulsion system" (NASA SP ]8072). This methodology, which is outlined in Reference 1, has been verified as a reliable means of determining the noise source characteristics of rocket engines. This information is being provided to establish reference environments for new government/business residents to ascertain whether or not their activities will generate acoustic environments that are more "encroaching" in the NASA Fee Area. In this report, the designation of sound power level refers to the acoustic power of the rocket engine at the engine itself. This is in contrast to the sound pressure level associated with the propagation of the acoustic energy in the surrounding air. The first part of the survey documents the "at source" sound power levels and their dominant frequency bands for the range of engines tested at Stennis. The second part of the survey discusses how the acoustic energy levels will propagate non ]uniformly from the test stands. To demonstrate this, representative acoustic sound pressure mappings in the NASA Stennis Fee Area were computed for typical engine tests on the B ]1 and E ]1 test stands.

  13. Startling Sweet Temptations: Hedonic Chocolate Deprivation Modulates Experience, Eating Behavior, and Eyeblink Startle

    PubMed Central

    Blechert, Jens; Naumann, Eva; Schmitz, Julian; Herbert, Beate M.; Tuschen-Caffier, Brunna

    2014-01-01

    Many individuals restrict their food intake to prevent weight gain. This restriction has both homeostatic and hedonic effects but their relative contribution is currently unclear. To isolate hedonic effects of food restriction, we exposed regular chocolate eaters to one week of chocolate deprivation but otherwise regular eating. Before and after this hedonic deprivation, participants viewed images of chocolate and images of high-calorie but non-chocolate containing foods, while experiential, behavioral and eyeblink startle responses were measured. Compared to satiety, hedonic deprivation triggered increased chocolate wanting, liking, and chocolate consumption but also feelings of frustration and startle potentiation during the intertrial intervals. Deprivation was further characterized by startle inhibition during both chocolate and food images relative to the intertrial intervals. Individuals who responded with frustration to the manipulation and those who scored high on a questionnaire of impulsivity showed more relative startle inhibition. The results reveal the profound effects of hedonic deprivation on experiential, behavioral and attentional/appetitive response systems and underscore the role of individual differences and state variables for startle modulation. Implications for dieting research and practice as well as for eating and weight disorders are discussed. PMID:24416437

  14. Startling sweet temptations: hedonic chocolate deprivation modulates experience, eating behavior, and eyeblink startle.

    PubMed

    Blechert, Jens; Naumann, Eva; Schmitz, Julian; Herbert, Beate M; Tuschen-Caffier, Brunna

    2014-01-01

    Many individuals restrict their food intake to prevent weight gain. This restriction has both homeostatic and hedonic effects but their relative contribution is currently unclear. To isolate hedonic effects of food restriction, we exposed regular chocolate eaters to one week of chocolate deprivation but otherwise regular eating. Before and after this hedonic deprivation, participants viewed images of chocolate and images of high-calorie but non-chocolate containing foods, while experiential, behavioral and eyeblink startle responses were measured. Compared to satiety, hedonic deprivation triggered increased chocolate wanting, liking, and chocolate consumption but also feelings of frustration and startle potentiation during the intertrial intervals. Deprivation was further characterized by startle inhibition during both chocolate and food images relative to the intertrial intervals. Individuals who responded with frustration to the manipulation and those who scored high on a questionnaire of impulsivity showed more relative startle inhibition. The results reveal the profound effects of hedonic deprivation on experiential, behavioral and attentional/appetitive response systems and underscore the role of individual differences and state variables for startle modulation. Implications for dieting research and practice as well as for eating and weight disorders are discussed.

  15. Role of the substantia nigra pars reticulata in sensorimotor gating, measured by prepulse inhibition of startle in rats.

    PubMed

    Koch, M; Fendt, M; Kretschmer, B D

    2000-12-20

    The substantia nigra pars reticulata (SNR) is one of the major output nuclei of the basal ganglia. It connects the dorsal and ventral striatum with the thalamus, superior colliculus and pontomedullary brainstem. The SNR is therefore in a strategic position to regulate sensorimotor behavior. We here assessed the effects of SNR lesions on prepulse inhibition (PPI) of the acoustic startle response (ASR), stereotypy and locomotion in drug-free rats, as well as after systemic administration of the dopamine agonist DL-amphetamine (2 mg/kg), and the NMDA receptor antagonists dizocilpine (0.16 mg/kg) and CGP 40116 (2 mg/kg). SNR lesions reduced PPI, enhanced spontaneous sniffing and potentiated the locomotor stimulation by dizocilpine and CGP 40116. PPI was impaired by dizocilpine and CGP 40116 in controls. The ASR was enhanced in controls by dizocilpine and amphetamine. SNR lesions prevented the enhancement of the ASR by amphetamine. A second experiment tested the hypothesis that the SNR mediates PPI via a GABAergic inhibition of the startle pathway. Infusion of the GABA(B) antagonist phaclofen but not the GABA(A) antagonist picrotoxin into the caudal pontine reticular nucleus reduced PPI. Hence, lesion of the SNR reduces sensorimotor gating possibly by elimination of a nigroreticular GABAergic projection interacting with GABA(B) receptors. Moreover, destruction of the SNR enhances the motor stimulatory effects of amphetamine and of the NMDA antagonists dizocilpine and CGP 40116. We conclude that the SNR exerts a tonic GABAergic inhibition on sensorimotor behavior that is regulated by the dorsal and the ventral striatum.

  16. Supertaster, super reactive: oral sensitivity for bitter taste modulates emotional approach and avoidance behavior in the affective startle paradigm.

    PubMed

    Herbert, Cornelia; Platte, Petra; Wiemer, Julian; Macht, Michael; Blumenthal, Terry D

    2014-08-01

    People differ in both their sensitivity for bitter taste and their tendency to respond to emotional stimuli with approach or avoidance. The present study investigated the relationship between these sensitivities in an affective picture paradigm with startle responding. Emotion-induced changes in arousal and attention (pupil modulation), priming of approach and avoidance behavior (startle reflex modulation), and subjective evaluations (ratings) were examined. Sensitivity for bitter taste was assessed with the 6-n-propylthiouracil (PROP)-sensitivity test, which discriminated individuals who were highly sensitive to PROP compared to NaCl (PROP-tasters) and those who were less sensitive or insensitive to the bitter taste of PROP. Neither pupil responses nor picture ratings differed between the two taster groups. The startle eye blink response, however, significantly differentiated PROP-tasters from PROP-insensitive subjects. Facilitated response priming to emotional stimuli emerged in PROP-tasters but not in PROP-insensitive subjects at shorter startle lead intervals (200-300ms between picture onset and startle stimulus onset). At longer lead intervals (3-4.5s between picture onset and startle stimulus onset) affective startle modulation did not differ between the two taster groups. This implies that in PROP-sensitive individuals action tendencies of approach or avoidance are primed immediately after emotional stimulus exposure. These results suggest a link between PROP taste perception and biologically relevant patterns of emotional responding. Direct perception-action links have been proposed to underlie motivational priming effects of the startle reflex, and the present results extend these to the sensory dimension of taste.

  17. Test of acoustic tone source and propulsion performance of C8A Buffalo suppressor nozzle

    NASA Technical Reports Server (NTRS)

    Marrs, C. C.; Harkonen, D. L.; Okeefe, J. V.

    1974-01-01

    Results are presented for a static acoustic and propulsion performance ground test conducted at the Boeing hot nozzle facility on the C8A Buffalo noise suppressor nozzle. Various methods to remove a nozzle-associated 2000-Hz tone are evaluated. Results of testing this rectangular-array lobed nozzle for propulsion performance and acoustic directivity are reported. Recommendations for future nozzle modifications and further testing are included. Appendix A contains the test plan. Appendix B presents the test log. Appendix C contains plots of the one-third octave sound pressure levels recorded during the test. Appendix D describes the acoustic data recording and reduction systems. The performance data is tabulated in Appendix E.

  18. Langasite Surface Acoustic Wave Sensors: Fabrication and Testing

    SciTech Connect

    Zheng, Peng; Greve, David W.; Oppenheim, Irving J.; Chin, Tao-Lun; Malone, Vanessa

    2012-02-01

    We report on the development of harsh-environment surface acoustic wave sensors for wired and wireless operation. Surface acoustic wave devices with an interdigitated transducer emitter and multiple reflectors were fabricated on langasite substrates. Both wired and wireless temperature sensing was demonstrated using radar-mode (pulse) detection. Temperature resolution of better than ±0.5°C was achieved between 200°C and 600°C. Oxygen sensing was achieved by depositing a layer of ZnO on the propagation path. Although the ZnO layer caused additional attenuation of the surface wave, oxygen sensing was accomplished at temperatures up to 700°C. The results indicate that langasite SAW devices are a potential solution for harsh-environment gas and temperature sensing.

  19. LATTE - Linking Acoustic Tests and Tagging Using Statistical Estimation

    DTIC Science & Technology

    2014-09-30

    animals exposed to acoustic stimuli); (2) medium-term satellite tagging studies of individual whales (some of which we hope will come from data...models and predictions will be directly applicable to animals in that area, although we hope they will be of more general relevance. Outputs of the...a simulation exercise (or any other relevant exercise) about the distribution of animals on the AUTEC range. Figure 1. The empirical

  20. Multiple Convergence Zone Acoustic Telemetry Feasibility Test Report

    DTIC Science & Technology

    1991-11-01

    oseq oseqr body Multiple Convergence Zone Acoustic Telemetry Feasibility Tesi ReportNovemrber 6. 199153 53 pack oseq=[ipfill([- 1 1 -1I1 -1 -111 -1 -1...Convergpnce Zonc Acoumtic Telcmetry Feasibdity Tesi Rertm.Nvcmbcr 6, 199180 80 oseq=oseq.*exp((sqrt(- I )*2*pi*(fO/fs))*(O: 1 :length(oseq)- I)); pnstrn...Stella Sanchez -Wade Pell Marine Science Library Documents Section University of Rhode Island Scripps Institution of Oceanography Narragansett Bay Campus

  1. Auditory startle reflex inhibited by preceding self-action.

    PubMed

    Kawachi, Yousuke; Matsue, Yoshihiko; Shibata, Michiaki; Imaizumi, Osamu; Gyoba, Jiro

    2014-01-01

    A startle reflex to a startle pulse is inhibited when preceded by a prestimulus. We introduced a key-press action (self-action) or an 85 dB noise burst as a prestimulus, followed by a 115 dB noise burst as a startle pulse. We manipulated temporal offsets between the prestimulus and the startle pulse from 30-1,500 ms to examine whether self-action modulates the startle reflex and the temporal properties of the modulatory effect. We assessed eyeblink reflexes by electromyography. Both prestimuli decreased reflexes compared to pulse-alone trials. Moreover, the temporal windows of inhibition were different between the types of prestimuli. A faster maximal inhibition and narrower temporal window in self-action trials suggest that preceding self-action inhibits the startle reflex and allows prediction of the coming pulse in different ways from auditory prestimuli.

  2. Investigation of the effects of head irradiation with gamma rays and protons on startle and pre-pulse inhibition behavior in mice.

    PubMed

    Haerich, Paul; Eggers, Cara; Pecaut, Michael J

    2012-05-01

    With the increased international emphasis on manned space exploration, there is a growing need to understand the impact of the spaceflight environment on health and behavior. One particularly important aspect of this environment is low-dose radiation. In the present studies, we first characterized the γ- and proton-irradiation dose effect on acoustic startle and pre-pulse inhibition behaviors in mice exposed to 0-5 Gy brain-localized irradiation, and assessed these effects 2 days later. Subsequently, we used 2 Gy to assess the time course of γ- and proton-radiation effects on startle reactivity 0-8 days after exposure. Exposures targeted the brain to minimize the impact of peripheral inflammation-induced sickness behavior. The effects of radiation on startle were subtle and acute. Radiation reduced the startle response at 2 and 5 Gy. Following a 2-Gy exposure, the response reached a minimum at the 2-day point. Proton and γ-ray exposures did not differ in their impact on startle. We found there were no effects of radiation on pre-pulse inhibition of the startle response.

  3. Flight Acoustic Testing and Data Acquisition For the Rotor Noise Model (RNM)

    NASA Technical Reports Server (NTRS)

    Conner, David A.; Burley, Casey L.; Smith, Charles D.

    2006-01-01

    Two acoustic flight tests have been conducted on a remote test range at Eglin Air Force Base in the panhandle of Florida. The first was the Acoustics Week flight test conducted in September 2003. The second was the NASA Heavy Lift Rotorcraft Acoustics Flight Test conducted in October-November 2005. Benchmark acoustic databases were obtained for a number of rotorcraft and limited fixed wing vehicles for a variety of flight conditions. The databases are important for validation of acoustic prediction programs such as the Rotorcraft Noise Model (RNM), as well as for the development of low noise flight procedures and for environmental impact assessments. An overview of RNM capabilities and a detailed description of the RNM/ART (Acoustic Repropagation Technique) process are presented. The RNM/ART process is demonstrated using measured acoustic data for the MD600N. The RNM predictions for a level flyover speed sweep show the highest SEL noise levels on the flight track centerline occurred at the slowest vehicle speeds. At these slower speeds, broadband noise content is elevated compared to noise levels obtained at the higher speeds. A descent angle sweep shows that, in general, ground noise levels increased with increasing descent rates. Vehicle orientation in addition to vehicle position was found to significantly affect the RNM/ART creation of source noise semi-spheres for vehicles with highly directional noise characteristics and only mildly affect those with weak acoustic directionality. Based on these findings, modifications are proposed for RNM/ART to more accurately define vehicle and rotor orientation.

  4. Flight Acoustic Testing and For the Rotorcraft Noise Data Acquisition Model (RNM)

    NASA Technical Reports Server (NTRS)

    Burley, Casey L.; Smith, Charles D.; Conner, David A.

    2006-01-01

    Two acoustic flight tests have been conducted on a remote test range at Eglin Air Force Base in the panhandle of Florida. The first was the "Acoustics Week" flight test conducted in September 2003. The second was the NASA Heavy Lift Rotorcraft Acoustics Flight Test conducted in October-November 2005. Benchmark acoustic databases were obtained for a number of rotorcraft and limited fixed wing vehicles for a variety of flight conditions. The databases are important for validation of acoustic prediction programs such as the Rotorcraft Noise Model (RNM), as well as for the development of low noise flight procedures and for environmental impact assessments. An overview of RNM capabilities and a detailed description of the RNM/ART (Acoustic Repropagation Technique) process are presented. The RNM/ART process is demonstrated using measured acoustic data for the MD600N. The RNM predictions for a level flyover speed sweep show the highest SEL noise levels on the flight track centerline occurred at the slowest vehicle speeds. At these slower speeds, broadband noise content is elevated compared to noise levels obtained at the higher speeds. A descent angle sweep shows that, in general, ground noise levels increased with increasing descent rates. Vehicle orientation in addition to vehicle position was found to significantly affect the RNM/ART creation of source noise semi-spheres for vehicles with highly directional noise characteristics and only mildly affect those with weak acoustic directionality. Based on these findings, modifications are proposed for RNM/ART to more accurately define vehicle and rotor orientation.

  5. FJ44 Turbofan Engine Test at NASA Glenn Research Center's Aero-Acoustic Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    Lauer, Joel T.; McAllister, Joseph; Loew, Raymond A.; Sutliff, Daniel L.; Harley, Thomas C.

    2009-01-01

    A Williams International FJ44-3A 3000-lb thrust class turbofan engine was tested in the NASA Glenn Research Center s Aero-Acoustic Propulsion Laboratory. This report presents the test set-up and documents the test conditions. Farfield directivity, in-duct unsteady pressures, duct mode data, and phased-array data were taken and are reported separately.

  6. Acoustic emission non-destructive testing of structures using source location techniques.

    SciTech Connect

    Beattie, Alan G.

    2013-09-01

    The technology of acoustic emission (AE) testing has been advanced and used at Sandia for the past 40 years. AE has been used on structures including pressure vessels, fire bottles, wind turbines, gas wells, nuclear weapons, and solar collectors. This monograph begins with background topics in acoustics and instrumentation and then focuses on current acoustic emission technology. It covers the overall design and system setups for a test, with a wind turbine blade as the object. Test analysis is discussed with an emphasis on source location. Three test examples are presented, two on experimental wind turbine blades and one on aircraft fire extinguisher bottles. Finally, the code for a FORTRAN source location program is given as an example of a working analysis program. Throughout the document, the stress is on actual testing of real structures, not on laboratory experiments.

  7. Design, construction, activation, and operation of a high intensity acoustic test chamber

    NASA Technical Reports Server (NTRS)

    Kamel, L. T.

    1986-01-01

    The design philosophy, construction, integration, and activation of the high intensity acoustic test chamber for production acceptance testing of satellites are discussed. The 32,000 cubic-foot acoustic test cell consists of a steel reinforced concrete chamber with six electropneumatic noise generators. One of the innovative features of the chamber is a unique quarter horn assembly that acoustically couples the noise generators to the chamber. Design concepts, model testing, and evaluation results are presented. Considerations such as nitrogen versus compressed air source, digital closed loop spectrum control versus manual equalizers, and microprocessor based interlock systems are included. Construction difficulties, anomalies encountered, and their resolution are also discussed. Results of the readiness testing are highlighted.

  8. VCE early acoustic test results of General Electric's high-radius ratio coannular plug nozzle

    NASA Technical Reports Server (NTRS)

    Knott, P. R.; Brausch, J. F.; Bhutiani, P. K.; Majjigi, R. K.; Doyle, V. L.

    1980-01-01

    Results of variable cycle engine (VCE) early acoustic engine and model scale tests are presented. A summary of an extensive series of far field acoustic, advanced acoustic, and exhaust plume velocity measurements with a laser velocimeter of inverted velocity and temperature profile, high radius ratio coannular plug nozzles on a YJ101 VCE static engine test vehicle are reviewed. Select model scale simulated flight acoustic measurements for an unsuppressed and a mechanical suppressed coannular plug nozzle are also discussed. The engine acoustic nozzle tests verify previous model scale noise reduction measurements. The engine measurements show 4 to 6 PNdB aft quadrant jet noise reduction and up to 7 PNdB forward quadrant shock noise reduction relative to a fully mixed conical nozzle at the same specific thrust and mixed pressure ratio. The influences of outer nozzle radius ratio, inner stream velocity ratio, and area ratio are discussed. Also, laser velocimeter measurements of mean velocity and turbulent velocity of the YJ101 engine are illustrated. Select model scale static and simulated flight acoustic measurements are shown which corroborate that coannular suppression is maintained in forward speed.

  9. Individual differences in behavioral activation and cardiac vagal control influence affective startle modification.

    PubMed

    Yang, Xiao; Friedman, Bruce H

    2017-04-01

    The startle response (SR) has a close relationship with stress responses. Startle modification (SRM) has been widely used to study stress disorders (e.g., posttraumatic stress disorder). The framework of the behavioral inhibition and activation systems (BIS/BAS) has been thought to correspond with withdrawal and approach motivational processes underlying affective SRM and can influence stress reactivity. Vagally-mediated cardiac activity as indexed by heart rate variability (HRV) has been associated with SRM and regulatory processes during stress. In the present study, the influence of individual differences in the BIS/BAS and resting HRV on affective SRM were examined. Eighty-six subjects viewed affective pictures while acoustic SR stimuli were delivered. Individual differences in motivation were measured by the BIS/BAS scales. The magnitude of SR was assessed as electromyographic activity of the SR eyeblink during pictures of different valences. Resting HRV was derived from electrocardiography. In contrast to previous studies, the present results showed that startle inhibition and potentiation were related to BAS and HRV, but not to BIS. There was also an interaction of BAS and HRV, indicating that the relationship between HRV and SRM strengthened as BAS scores decreased. The present findings suggest that BAS may relate to both withdrawal and approach, and trait stress reactivity is influenced by BAS and cardiac vagal activity. In addition, BAS moderates the relationship between cardiac vagal activity and SRM. These findings have both theoretical and practical implications for the study of SRM, stress disorders, and health.

  10. The experimental determination of atmospheric absorption from aircraft acoustic flight tests

    NASA Technical Reports Server (NTRS)

    Miller, R. L.; Oncley, P. B.

    1971-01-01

    A method for determining atmospheric absorption coefficients from acoustic flight test data is presented. Measurements from five series of acoustic flight tests were included in the study. The number of individual flights totaled 24: six Boeing 707 flights performed in May 1969 in connection with the turbofan nacelle modification program, eight flights from Boeing tests conducted during the same period, and 10 flights of the Boeing 747 airplane. The effects of errors in acoustic, meteorological, and aircraft performance and position measurements are discussed. Tabular data of the estimated sample variance of the data for each test are given for source directivity angles from 75 deg to 120 deg and each 1/3-octave frequency band. Graphic comparisons are made of absorption coefficients derived from ARP 866, using atmospheric profile data, with absorption coefficients determined by the experimental method described in the report.

  11. Study of acoustic emission during mechanical tests of large flight weight tank structure

    NASA Technical Reports Server (NTRS)

    Mccauley, B. O.; Nakamura, Y.; Veach, C. L.

    1973-01-01

    A PPO-insulated, flight-weight, subscale, aluminum tank was monitored for acoustic emissions during a proof test and during 100 cycles of environmental test simulating space flights. The use of a combination of frequency filtering and appropriate spatial filtering to reduce background noise was found to be sufficient to detect acoustic emission signals of relatively small intensity expected from subcritical crack growth in the structure. Several emission source locations were identified, including the one where a flaw was detected by post-test x-ray inspections. For most source locations, however, post-test inspections did not detect flaws; this was partially attributed to the higher sensitivity of the acoustic emission technique than any other currently available NDT method for detecting flaws. For these non-verifiable emission sources, a problem still remains in correctly interpreting observed emission signals.

  12. Monitoring and Analysis of In-Pile Phenomena in Advanced Test Reactor using Acoustic Telemetry

    SciTech Connect

    Agarwal, Vivek; Smith, James A.; Jewell, James Keith

    2015-02-01

    The interior of a nuclear reactor presents a particularly harsh and challenging environment for both sensors and telemetry due to high temperatures and high fluxes of energetic and ionizing particles among the radioactive decay products. A number of research programs are developing acoustic-based sensing approach to take advantage of the acoustic transmission properties of reactor cores. Idaho National Laboratory has installed vibroacoustic receivers on and around the Advanced Test Reactor (ATR) containment vessel to take advantage of acoustically telemetered sensors such as thermoacoustic (TAC) transducers. The installation represents the first step in developing an acoustic telemetry infrastructure. This paper presents the theory of TAC, application of installed vibroacoustic receivers in monitoring the in-pile phenomena inside the ATR, and preliminary data processing results.

  13. Versatility of fear-potentiated startle paradigms for assessing human conditioned fear extinction and return of fear.

    PubMed

    Norrholm, Seth D; Anderson, Kemp M; Olin, Ilana W; Jovanovic, Tanja; Kwon, Cliffe; Warren, Victor T; McCarthy, Alexander; Bosshardt, Lauren; Sabree, Justin; Duncan, Erica J; Rothbaum, Barbara O; Bradley, Bekh

    2011-01-01

    Fear conditioning methodologies have often been employed as testable models for assessing learned fear responses in individuals with anxiety disorders such as post-traumatic stress disorder (PTSD) and specific phobia. One frequently used paradigm is measurement of the acoustic startle reflex under conditions that mimic anxiogenic and fear-related conditions. For example, fear-potentiated startle is the relative increase in the frequency or magnitude of the acoustic startle reflex in the presence of a previously neutral cue (e.g., colored shape; termed the conditioned stimulus or CS+) that has been repeatedly paired with an aversive unconditioned stimulus (e.g., airblast to the larynx). Our group has recently used fear-potentiated startle paradigms to demonstrate impaired fear extinction in civilian and combat populations with PTSD. In the current study, we examined the use of either auditory or visual CSs in a fear extinction protocol that we have validated and applied to human clinical conditions. This represents an important translational bridge in that numerous animal studies of fear extinction, upon which much of the human work is based, have employed the use of auditory CSs as opposed to visual CSs. Participants in both the auditory and visual groups displayed robust fear-potentiated startle to the CS+, clear discrimination between the reinforced CS+ and non-reinforced CS-, significant extinction to the previously reinforced CS+, and marked spontaneous recovery. We discuss the current results as they relate to future investigations of PTSD-related impairments in fear processing in populations with diverse medical and psychiatric histories.

  14. Aerodynamic and Acoustic Flight Test Results for the Stratospheric Observatory for Infrared Astronomy

    NASA Technical Reports Server (NTRS)

    Cumming, Stephen B.; Cliatt, Larry James; Frederick, Michael A.; Smith, Mark S.

    2013-01-01

    As part of the Stratospheric Observatory for Infrared Astronomy (SOFIA) program, a 747SP airplane was modified to carry a 2.5 meter telescope in the aft section of the fuselage. The resulting airborne observatory allows for observations above 99 percent of the water vapor in the atmosphere. The open cavity created by the modifications had the potential to significantly affect the airplane in the areas of aerodynamics and acoustics. Several series of flight tests were conducted to clear the airplanes operating envelope for astronomical observations, planned to be performed between the altitudes of 39,000 feet and 45,000 feet. The flight tests were successfully completed. Cavity acoustics were below design limits, and the overall acoustic characteristics of the cavity were better than expected. The modification did have some effects on the stability and control of the airplane, but these effects were not significant. Airplane air data systems were not affected by the modifications. This paper describes the methods used to examine the aerodynamics and acoustic data from the flight tests and provides a discussion of the flight test results in the areas of cavity acoustics, stability and control, and air data.

  15. Aerodynamic and Acoustic Flight Test Results and Results for the Stratospheric Observatory for Infrared Astronomy

    NASA Technical Reports Server (NTRS)

    Cumming, Stephen B.; Smith, Mark S.; Cliatt, Larry J.; Frederick, Michael A.

    2014-01-01

    As part of the Stratospheric Observatory for Infrared Astronomy program, a 747SP airplane was modified to carry a 2.5-m telescope in the aft section of the fuselage. The resulting airborne observatory allows for observations above 99 percent of the water vapor in the atmosphere. The open cavity created by the modifications had the potential to significantly affect the airplane in the areas of aerodynamics and acoustics. Several series of flight tests were conducted to clear the operating envelope of the airplane for astronomical observations, planned to be performed between the altitudes of 35,000 ft and 45,000 ft. The flight tests were successfully completed. Cavity acoustics were below design limits, and the overall acoustic characteristics of the cavity were better than expected. The modification did have some effects on the stability and control of the airplane, but these effects were not significant. Airplane air data systems were not affected by the modifications. This paper describes the methods used to examine the aerodynamics and acoustic data from the flight tests and provides a discussion of the flight-test results in the areas of cavity acoustics, stability and control, and air data.

  16. Closed-Loop Acoustic Control of Reverberant Room for Satellite Environmental Testing

    NASA Astrophysics Data System (ADS)

    Janssens, Karl; Bianciardi, Fabio; Sabbatini, Danilo; Debille, Jan; Carrella, Alex

    2012-07-01

    The full satellite acoustic test is an important milestone in a satellite launch survivability verification campaign. This test is required to verify the satellite’s mechanical design against the high-level acoustic loads induced by the launch vehicle during the atmospheric flight. During the test, the satellite is subjected to a broadband diffuse acoustic field, reproducing the pressure levels observed during launch. The excitation is in most cases provided by a combination of horns for the low frequencies and noise generators for the higher frequencies. Acoustic control tests are commonly performed in reverberant rooms, controlling the sound pressure levels in third octave bands over the specified target spectrum. This paper discusses an automatic feedback control system for acoustic control of large reverberation rooms for satellite environmental testing. The acoustic control system consists of parallel third octave PI (Proportional Integral) feedback controllers that take the reverberation characteristics of the room into consideration. The drive output of the control system is shaped at every control step based on the comparison of the average third octave noise spectrum, measured from a number of microphones in the test room, with the target spectrum. Cross-over filters split the output drive into band- limited signals to feed each of the horns. The control system is realized in several steps. In the first phase, a dynamic process model is developed, including the non-linear characteristics of the horns and the reverberant properties of the room. The model is identified from dynamic experiments using system identification techniques. In the next phase, an adequate control strategy is designed which is capable of reaching the target spectrum in the required time period without overshoots. This control strategy is obtained from model-in-the-loop (MIL) simulations, evaluating the performance of various potential strategies. Finally, the proposed strategy is

  17. Characterization of acoustic lenses with the Foucault test by confocal laser scanning microscopy

    NASA Astrophysics Data System (ADS)

    Ahmed Mohamed, E. T.; Abdelrahman, A.; Pluta, M.; Grill, W.

    2010-03-01

    In this work, the Foucault knife-edge test, which has traditionally been known as the classic test for optical imaging devices, is used to characterize an acoustic lens for operation at 1.2 GHz. A confocal laser scanning microscope (CLSM) was used as the illumination and detection device utilizing its pinhole instead of the classical knife edge that is normally employed in the Foucault test. Information about the geometrical characteristics, such as the half opening angle of the acoustic lens, were determined as well as the quality of the calotte of the lens used for focusing. The smallest focal spot size that could be achieved with the examined lens employed as a spherical reflector was found to be about 1 μm. By comparison to the idealized resolution a degradation of about a factor of 2 can be deduced. This limits the actual quality of the acoustic focus.

  18. Startle Response in Progressive Myoclonic Epilepsy.

    PubMed

    Kızıltan, Meral E; Gündüz, Ayşegül; Coşkun, Tülin; Delil, Şakir; Pazarcı, Nevin; Özkara, Çiğdem; Yeni, Naz

    2017-03-01

    Cortical reflex myoclonus is a typical feature of progressive myoclonic epilepsy (PME) in which it is accompanied by other types of mostly drug-resistant seizures and progressive neurological signs. Although PME is characterized by cortical hyperexcitability, studies have demonstrated atrophy and degenerative changes in the brainstem in various types of PME. Thus, we have questioned whether any stimuli may trigger a hyperactive response of brainstem reticular formation in PME and investigated the startle reflex in individuals with PME. We recorded the auditory startle response (ASR) and the startle response to somatosensory inputs (SSS) in patients with PME, and compared the results with healthy volunteers and patients with other types of drug-resistant epilepsy. All patients were using antiepileptic drugs (AEDs), 12 were on multiple AEDs. The probability of ASR was significantly lower and mean onset latency was longer in patients with PME compared with other groups. SSS responses over all muscles were low in both the PME and drug-resistant epilepsy groups; however, the differences were not statistically significant. The presence of a response over the biceps brachii muscle was zero in the PME group and showed a borderline difference compared with the other groups. Decreased probability and prolonged latencies of ASR in PME indicate inhibition of reflex circuit. A trend for decreased responses of SSS suggests hypoactive SSS in both PME and other epilepsy groups. Hypoactive ASR in PME and hypoactive SSS in both PME and other epilepsies may be attributed to the degeneration of pontine reticular nuclei in PME and functional inhibition by AEDs in both disorders.

  19. NASA Glenn's Acoustical Testing Laboratory Awarded Accreditation by the National Voluntary Laboratory Accreditation Program

    NASA Technical Reports Server (NTRS)

    Akers, James C.; Cooper, Beth A.

    2004-01-01

    NASA Glenn Research Center's Acoustical Testing Laboratory (ATL) provides a comprehensive array of acoustical testing services, including sound pressure level, sound intensity level, and sound-power-level testing per International Standards Organization (ISO)1 3744. Since its establishment in September 2000, the ATL has provided acoustic emission testing and noise control services for a variety of customers, particularly microgravity space flight hardware that must meet International Space Station acoustic emission requirements. The ATL consists of a 23- by 27- by 20-ft (height) convertible hemi/anechoic test chamber and a separate sound-attenuating test support enclosure. The ATL employs a personal-computer-based data acquisition system that provides up to 26 channels of simultaneous data acquisition with real-time analysis (ref. 4). Specialized diagnostic tools, including a scanning sound-intensity system, allow the ATL's technical staff to support its clients' aggressive low-noise design efforts to meet the space station's acoustic emission requirement. From its inception, the ATL has pursued the goal of developing a comprehensive ISO 17025-compliant quality program that would incorporate Glenn's existing ISO 9000 quality system policies as well as ATL-specific technical policies and procedures. In March 2003, the ATL quality program was awarded accreditation by the National Voluntary Laboratory Accreditation Program (NVLAP) for sound-power-level testing in accordance with ISO 3744. The NVLAP program is administered by the National Institutes of Standards and Technology (NIST) of the U.S. Department of Commerce and provides third-party accreditation for testing and calibration laboratories. There are currently 24 NVLAP-accredited acoustical testing laboratories in the United States. NVLAP accreditation covering one or more specific testing procedures conducted in accordance with established test standards is awarded upon successful completion of an intensive

  20. Comparative evaluation of test methods to simulate acoustic response of shroud-enclosed spacecraft structures

    NASA Technical Reports Server (NTRS)

    On, F. J.

    1975-01-01

    Test methods were evaluated to ascertain whether a spacecraft, properly tested within its shroud, could be vibroacoustic tested without the shroud, with adjustments made in the acoustic input spectra to simulate the acoustic response of the missing shroud. The evaluation was based on vibroacoustic test results obtained from a baseline model composed (1) of a spacecraft with adapter, lower support structure, and shroud; (2) of the spacecraft, adapter, and lower structure, but without the shroud; and (3) of the spacecraft and adapter only. Emphasis was placed on the magnitude of the acoustic input changes required to substitute for the shroud and the difficulty of making such input changes, and the degree of missimulation which can result from the performance of a particular, less-than optimum test. Conclusions are drawn on the advantages and disadvantages derived from the use of input spectra adjustment methods and lower support structure simulations. Test guidelines were also developed for planning and performing a launch acoustic-environmental test.

  1. Initial Evaluation of Acoustic Emission SHM of PRSEUS Multi-bay Box Tests

    NASA Technical Reports Server (NTRS)

    Horne, Michael R.; Madaras, Eric I.

    2016-01-01

    A series of tests of the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) HWB Multi-Bay Test Article were conducted during the second quarter of 2015 at NASA Langley Research Center (LaRC) in the Combined Loads Test facility (COLTS). This report documents the Acoustic Emission (AE) data collected during those tests along with an initial analysis of the data. A more detailed analysis will be presented in future publications.

  2. Multivariate acoustic detection of small explosions using Fisher's combined probability test.

    PubMed

    Arrowsmith, Stephen J; Taylor, Steven R

    2013-03-01

    A methodology for the combined acoustic detection and discrimination of explosions, which uses three discriminants, is developed for the purpose of identifying weak explosion signals embedded in complex background noise. By utilizing physical models for simple explosions that are formulated as statistical hypothesis tests, the detection/discrimination approach does not require a model for the background noise, which can be highly complex and variable in practice. Fisher's Combined Probability Test is used to combine the p-values from all multivariate discriminants. This framework is applied to acoustic data from a 400 g explosion conducted at Los Alamos National Laboratory.

  3. Design and construction of a reverberation chamber for high-intensity acoustic testing.

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1973-01-01

    A high-intensity acoustic test facility was constructed at the Jet Propulsion Laboratory (JPL) to support the Mariner Mars 1971 project. For ease of construction, the reverberation chamber itself is rectangular, which resulted in very little sacrifice in acoustic performance. Levels as high as 156 dB can be achieved with the chamber empty and test levels of 150 dB have been used with a Mariner Mars spacecraft model (full size) in the chamber. Levels as high as this must be generated using electropneumatic transducers, which modulate gaseous nitrogen to this facility.

  4. Acoustic Noise Test Report for the SWIFT Wind Turbine in Boulder, CO

    SciTech Connect

    Roadman, J.; Huskey, A.

    2013-04-01

    This report summarizes the results of an acoustic noise test that the National Renewable Energy Laboratory (NREL) conducted on the SWIFT wind turbine. This test was conducted in accordance with the International Electrotechnical Commission's (IEC) standard, Wind Turbine Generator Systems Part 11: Acoustic Noise Measurement Techniques, IEC 61400-11 Ed.2.1, 2006-11. However, because the SWIFT is a small turbine, as defined by IEC, NREL used 10-second averages instead of 60-second averages and utilized binning by wind speed instead of regression analysis.

  5. Acoustic Noise Test Report for the Viryd CS8 Wind Turbine

    SciTech Connect

    Roadman, J.; Huskey, A.

    2013-07-01

    This report summarizes the results of an acoustic noise test that the National Renewable Energy Laboratory (NREL) conducted on the Viryd CS8 wind turbine. This test was conducted in accordance with the International Electrotechnical Commission's (IEC) standard, Wind Turbine Generator Systems Part 11: Acoustic Noise Measurement Techniques, IEC 61400-11 Ed.2.1, 2006-11. However, because the Viryd CS8 is a small turbine, as defined by IEC, NREL used 10-second averages instead of 60-second averages and binning by wind speed instead of regression analysis.

  6. Affect Modulated Startle in Schizophrenia: Subjective Experience Matters

    PubMed Central

    Dominelli, Rachelle M.; Boggs, Jennifer M.; Bolbecker, Amanda R.; O'Donnell, Brian F.; Hetrick, William P.; Brenner, Colleen A.

    2014-01-01

    Data suggests that emotion reactivity as measured by the affect-modulated startle paradigm in those with schizophrenia (SZ) may be similar to healthy controls (HC). However, normative classification of the stimuli may not accurately reflect emotional experience, especially for those with SZ. To examine this possibility, the present study measured the affect-modulated startle response with images classified according to both normative and subjective ratings. Seventeen HC and 17 SZ completed an image viewing task during which startle probes were presented, followed by subjective valence and arousal ratings. Both groups exhibited inhibited startle responses to positive images, intermediate startle amplitudes to neutral images, and potentiated startle amplitudes to negative images. SZ rated the positive images as less positive than HC. When images were reclassified based on subjective valence ratings, both groups’ startle magnitudes increased in response to subjectively rated positive images and decreased to subjectively rated neutral images. The number of trials classified into each valence condition suggested a tendency for SZ to classify neutral images as negative more often than HC. Overall, these findings suggest that affective stimuli modulate the startle response in HC and SZ in similar ways, but subjective emotional experience may differ in those with schizophrenia. PMID:25107317

  7. Acoustic Treatment Design Scaling Methods. Volume 3; Test Plans, Hardware, Results, and Evaluation

    NASA Technical Reports Server (NTRS)

    Yu, J.; Kwan, H. W.; Echternach, D. K.; Kraft, R. E.; Syed, A. A.

    1999-01-01

    The ability to design, build, and test miniaturized acoustic treatment panels on scale-model fan rigs representative of the full-scale engine provides not only a cost-savings, but an opportunity to optimize the treatment by allowing tests of different designs. To be able to use scale model treatment as a full-scale design tool, it is necessary that the designer be able to reliably translate the scale model design and performance to an equivalent full-scale design. The primary objective of the study presented in this volume of the final report was to conduct laboratory tests to evaluate liner acoustic properties and validate advanced treatment impedance models. These laboratory tests include DC flow resistance measurements, normal incidence impedance measurements, DC flow and impedance measurements in the presence of grazing flow, and in-duct liner attenuation as well as modal measurements. Test panels were fabricated at three different scale factors (i.e., full-scale, half-scale, and one-fifth scale) to support laboratory acoustic testing. The panel configurations include single-degree-of-freedom (SDOF) perforated sandwich panels, SDOF linear (wire mesh) liners, and double-degree-of-freedom (DDOF) linear acoustic panels.

  8. Experimental aerodynamic and acoustic model testing of the Variable Cycle Engine (VCE) testbed coannular exhaust nozzle system: Comprehensive data report

    NASA Technical Reports Server (NTRS)

    Nelson, D. P.; Morris, P. M.

    1980-01-01

    The component detail design drawings of the one sixth scale model of the variable cycle engine testbed demonstrator exhaust syatem tested are presented. Also provided are the basic acoustic and aerodynamic data acquired during the experimental model tests. The model drawings, an index to the acoustic data, an index to the aerodynamic data, tabulated and graphical acoustic data, and the tabulated aerodynamic data and graphs are discussed.

  9. A Screening Approach for Classroom Acoustics Using Web-Based Listening Tests and Subjective Ratings

    PubMed Central

    Persson Waye, Kerstin; Magnusson, Lennart; Fredriksson, Sofie; Croy, Ilona

    2015-01-01

    Background Perception of speech is crucial in school where speech is the main mode of communication. The aim of the study was to evaluate whether a web based approach including listening tests and questionnaires could be used as a screening tool for poor classroom acoustics. The prime focus was the relation between pupils’ comprehension of speech, the classroom acoustics and their description of the acoustic qualities of the classroom. Methodology/Principal Findings In total, 1106 pupils aged 13-19, from 59 classes and 38 schools in Sweden participated in a listening study using Hagerman’s sentences administered via Internet. Four listening conditions were applied: high and low background noise level and positions close and far away from the loudspeaker. The pupils described the acoustic quality of the classroom and teachers provided information on the physical features of the classroom using questionnaires. Conclusions/Significance In 69% of the classes, at least three pupils described the sound environment as adverse and in 88% of the classes one or more pupil reported often having difficulties concentrating due to noise. The pupils’ comprehension of speech was strongly influenced by the background noise level (p<0.001) and distance to the loudspeakers (p<0.001). Of the physical classroom features, presence of suspended acoustic panels (p<0.05) and length of the classroom (p<0.01) predicted speech comprehension. Of the pupils’ descriptions of acoustic qualities, clattery significantly (p<0.05) predicted speech comprehension. Clattery was furthermore associated to difficulties understanding each other, while the description noisy was associated to concentration difficulties. The majority of classrooms do not seem to have an optimal sound environment. The pupil’s descriptions of acoustic qualities and listening tests can be one way of predicting sound conditions in the classroom. PMID:25615692

  10. F-16XL and F-18 High Speed Acoustic Flight Test Databases

    NASA Technical Reports Server (NTRS)

    Kelly, J. J.; Wilson, M. R.; Rawls, J., Jr.; Norum, T. D.; Golub, R. A.

    1999-01-01

    This report presents the recorded acoustic data and the computed narrow-band and 1/3-octave band spectra produced by F-18 and F-16XL aircraft in subsonic flight over an acoustic array. Both broadband-shock noise and turbulent mixing noise are observed in the spectra. Radar and c-band tracking systems provided the aircraft position which enabled directivity and smear angles from the aircraft to each microphone to be computed. These angles are based on source emission time and thus give some idea about the directivity of the radiated sound field due to jet noise. A follow-on static test was also conducted where acoustic and engine data were obtained. The acoustic data described in the report has application to community noise analysis, noise source characterization and validation of prediction models. A detailed description of the signal processing procedures is provided. Follow-on static tests of each aircraft were also conducted for which engine data and far-field acoustic data are presented.

  11. Passive Acoustic Tomography Tested for Measuring Gas Temperatures

    NASA Technical Reports Server (NTRS)

    Fralick, Gustave C.; Kleppe, John

    2004-01-01

    tomography by sound waves. Active acoustic tomography, in which a sound pulse is injected into the flow and the time delays between members of an array of microphones are used to construct the temperature field has been used successfully in the stacks of power plants. However, the flow field inside a jet engine is much too noisy for it to be possible to detect an externally injected sound pulse. Instead we are developing passive acoustic tomography, which uses the sound already present in the flow.

  12. Acoustic-Modal Testing of the Ares I Launch Abort System Attitude Control Motor Valve

    NASA Technical Reports Server (NTRS)

    Davis, R. Benjamin; Fischbach, Sean R.

    2010-01-01

    The Attitude Control Motor (ACM) is being developed for use in the Launch Abort System (LAS) of NASA's Ares I launch vehicle. The ACM consists of a small solid rocket motor and eight actuated pintle valves that directionally allocate.thrust_- 1t.has-been- predicted-that significant unsteady. pressure.fluctuations.will.exist. inside the-valves during operation. The dominant frequencies of these oscillations correspond to the lowest several acoustic natural frequencies of the individual valves. An acoustic finite element model of the fluid volume inside the valve has been critical to the prediction of these frequencies and their associated mode shapes. This work describes an effort to experimentally validate the acoustic finite model of the valve with an acoustic modal test. The modal test involved instrumenting a flight-like valve with six microphones and then exciting the enclosed air with a loudspeaker. The loudspeaker was configured to deliver broadband noise at relatively high sound pressure levels. The aquired microphone signals were post-processed and compared to results generated from the acoustic finite element model. Initial comparisons between the test data and the model results revealed that additional model refinement was necessary. Specifically, the model was updated to implement a complex impedance boundary condition at the entrance to the valve supply tube. This boundary condition models the frequency-dependent impedance that an acoustic wave will encounter as it reaches the end of the supply tube. Upon invoking this boundary condition, significantly improved agreement between the test data and the model was realized.

  13. Planning of Ballistic Movement following Stroke: Insights from the Startle Reflex

    PubMed Central

    Honeycutt, Claire Fletcher; Perreault, Eric Jon

    2012-01-01

    Following stroke, reaching movements are slow, segmented, and variable. It is unclear if these deficits result from a poorly constructed movement plan or an inability to voluntarily execute an appropriate plan. The acoustic startle reflex provides a means to initiate a motor plan involuntarily. In the presence of a movement plan, startling acoustic stimulus triggers non-voluntary early execution of planned movement, a phenomenon known as the startReact response. In unimpaired individuals, the startReact response is identical to a voluntarily initiated movement, except that it is elicited 30–40 ms. As the startReact response is thought to be mediated by brainstem pathways, we hypothesized that the startReact response is intact in stroke subjects. If startReact is intact, it may be possible to elicit more task-appropriate patterns of muscle activation than can be elicited voluntarily. We found that startReact responses were intact following stroke. Responses were initiated as rapidly as those in unimpaired subjects, and with muscle coordination patterns resembling those seen during unimpaired volitional movements. Results were striking for elbow flexion movements, which demonstrated no significant differences between the startReact responses elicited in our stroke and unimpaired subject groups. The results during planned extension movements were less straightforward for stroke subjects, since the startReact response exhibited task inappropriate activity in the flexors. This inappropriate activity diminished over time. This adaptation suggests that the inappropriate activity was transient in nature and not related to the underlying movement plan. We hypothesize that the task-inappropriate flexor activity during extension results from an inability to suppress the classic startle reflex, which primarily influences flexor muscles and adapts rapidly with successive stimuli. These results indicate that stroke subjects are capable of planning ballistic elbow movements

  14. Testing the odontocete acoustic prey debilitation hypothesis: no stunning results.

    PubMed

    Benoit-Bird, Kelly J; Au, Whitlow W L; Kastelein, Ronald

    2006-08-01

    The hypothesis that sounds produced by odontocetes can debilitate fish was examined. The effects of simulated odontocete pulsed signals on three species of fish commonly preyed on by odontocetes were examined, exposing three individuals of each species as well as groups of four fish to a high-frequency click of a bottlenose dolphin [peak frequency (PF) 120 kHz, 213-dB peak-to-peak exposure level (EL)], a midfrequency click modeled after a killer whale's signal (PF 55 kHz, 208-dB EL), and a low-frequency click (PF 18 kHz, 193-dB EL). Fish were held in a 50-cm diameter net enclosure immediately in front of a transducer where their swimming behavior, orientation, and balance were observed with two video cameras. Clicks were presented at constant rates and in graded sweeps simulating a foraging dolphin's "terminal buzz." No measurable change in behavior was observed in any of the fish for any signal type or pulse modulation rate, despite the fact that clicks were at or near the maximum source levels recorded for odontocetes. Based on the results, the hypothesis that acoustic signals of odontocetes alone can disorient or "stun" prey cannot be supported.

  15. Acoustical Testing Laboratory Developed to Support the Low-Noise Design of Microgravity Space Flight Hardware

    NASA Technical Reports Server (NTRS)

    Cooper, Beth A.

    2001-01-01

    The NASA John H. Glenn Research Center at Lewis Field has designed and constructed an Acoustical Testing Laboratory to support the low-noise design of microgravity space flight hardware. This new laboratory will provide acoustic emissions testing and noise control services for a variety of customers, particularly for microgravity space flight hardware that must meet International Space Station limits on noise emissions. These limits have been imposed by the space station to support hearing conservation, speech communication, and safety goals as well as to prevent noise-induced vibrations that could impact microgravity research data. The Acoustical Testing Laboratory consists of a 23 by 27 by 20 ft (height) convertible hemi/anechoic chamber and separate sound-attenuating test support enclosure. Absorptive 34-in. fiberglass wedges in the test chamber provide an anechoic environment down to 100 Hz. A spring-isolated floor system affords vibration isolation above 3 Hz. These criteria, along with very low design background levels, will enable the acquisition of accurate and repeatable acoustical measurements on test articles, up to a full space station rack in size, that produce very little noise. Removable floor wedges will allow the test chamber to operate in either a hemi/anechoic or anechoic configuration, depending on the size of the test article and the specific test being conducted. The test support enclosure functions as a control room during normal operations but, alternatively, may be used as a noise-control enclosure for test articles that require the operation of noise-generating test support equipment.

  16. Recent Improvements to the Acoustical Testing Laboratory at the NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Podboy, Devin M.; Mirecki, Julius H.; Walker, Bruce E.; Sutliff, Daniel L.

    2014-01-01

    The Acoustical Testing Laboratory (ATL) consists of a 27 by 23 by 20 ft (height) convertible hemi/anechoic chamber and separate sound-attenuating test support enclosure. Absorptive fiberglass wedges in the test chamber provide an anechoic environment down to 100 Hz. A spring-isolated floor system affords vibration isolation above 3 Hz. These specifications, along with very low design background levels, enable the acquisition of accurate and repeatable acoustical measurements on test articles that produce very low sound pressures. Removable floor wedges allow the test chamber to operate in either a hemi-anechoic or anechoic configuration, depending on the size of the test article and the specific test being conducted. The test support enclosure functions as a control room during normal operations. Recently improvements were accomplished in support of continued usage of the ATL by NASA programs including an analysis of the ultra-sonic characteristics. A 3 dimensional traverse system inside the chamber was utilized for acquiring acoustic data for these tests. The traverse system drives a linear array of 13, 1/4"-microphones spaced 3" apart (36" span). An updated data acquisition system was also incorporated into the facility.

  17. Recent Improvements to the Acoustical Testing Laboratory at the NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Podboy, Devin M.; Mirecki, Julius H.; Walker, Bruce E.; Sutliff, Daniel L.

    2014-01-01

    The Acoustical Testing Laboratory (ATL) consists of a 27- by 23- by 20-ft (height) convertible hemi/anechoic chamber and separate sound-attenuating test support enclosure. Absorptive fiberglass wedges in the test chamber provide an anechoic environment down to 100 Hz. A spring-isolated floor system affords vibration isolation above 3 Hz. These specifications, along with very low design background levels, enable the acquisition of accurate and repeatable acoustical measurements on test articles that produce very low sound pressures. Removable floor wedges allow the test chamber to operate in either a hemi-anechoic or anechoic configuration, depending on the size of the test article and the specific test being conducted. The test support enclosure functions as a control room during normal operations. Recently improvements were accomplished in support of continued usage of the ATL by NASA programs including an analysis of the ultra-sonic characteristics. A 3-D traverse system inside the chamber was utilized for acquiring acoustic data for these tests. The traverse system drives a linear array of 13, 1/4 in.-microphones spaced 3 in. apart (36 in. span). An updated data acquisition system was also incorporated into the facility.

  18. Design and Integration of a Rotor Alone Nacelle for Acoustic Fan Testing

    NASA Technical Reports Server (NTRS)

    Shook, Tony D.; Hughes, Christoper E.; Thompson, William K.; Tavernelli, Paul F.; Cunningham, Cameron C.; Shah, Ashwin

    2001-01-01

    A brief summary of the design, integration and testing of a rotor alone nacelle (RAN) in NASA Glenn's 9'x 15' Low Speed Wind Tunnel (LSWT) is presented. The purpose of the RAN system was to provide an "acoustically clean" flow path within the nacelle to isolate that portion of the total engine system acoustic signature attributed to fan noise. The RAN design accomplished this by removing the stators that provided internal support to the nacelle. In its place, two external struts mounted to a two-axis positioning table located behind the tunnel wall provided the support. Nacelle-mounted lasers and a closed-loop control system provided the input to the table to maintain nacelle to fan concentricity as thermal and thrust loads displaced the strut-mounted fan. This unique design required extensive analysis and verification testing to ensure the safety of the fan model, propulsion simulator drive rig, and facility, along with experimental consistency of acoustic data obtained while using the RAN system. Initial testing was used to optimize the positioning system and resulted in concentricity errors of +/- 0.0031 in. in the horizontal direction and +0.0035/-0.0013 in, in the vertical direction. As a result of successful testing, the RAN system will be transitioned into other acoustic research programs at NASA Glenn Research Center.

  19. Characterization Test Report for the Mnemonics-UCS Wireless Surface Acoustic Wave Sensor System

    NASA Technical Reports Server (NTRS)

    Duncan, Joshua J.; Youngquist, Robert C.

    2013-01-01

    The scope of this testing includes the Surface Acoustic Wave Sensor System delivered to KSC: two interrogator (transceiver) systems, four temperature sensors, with wooden mounting blocks, two antennas, two power supplies, network cables, and analysis software. Also included are a number of additional temperature sensors and newly-developed hydrogen sensors

  20. Results of acoustic testing of the JT8D-109 refan engines

    NASA Technical Reports Server (NTRS)

    Burdsall, E. A.; Brochu, F. P.; Scaramella, V. M.

    1975-01-01

    A JT8D engine was modified to reduce jet noise levels by 6-8 PNdB at takeoff power without increasing fan generated noise levels. Designated the JT8D-109, the modified engines featured a larger single stage fan, and acoustic treatment in the fan discharge ducts. Noise levels were measured on an outdoor test facility for eight engine/acoustic treatment configurations. Compared to the baseline JT8D, the fully treated JT8D-109 showed reductions of 6 PNdB at takeoff, and 11 PNdB at a typical approach power setting.

  1. Assessment of Startle Response and Its Prepulse Inhibition Using Posturography: Pilot Study

    PubMed Central

    Polechoński, Jacek; Juras, Grzegorz; Słomka, Kajetan; Błaszczyk, Janusz; Małecki, Andrzej; Nawrocka, Agnieszka

    2016-01-01

    Purpose. The aim of this study was to evaluate the possibility of using static posturography in the assessment of sensorimotor gating. Subjects and Methods. Fourteen subjects took part in the experiment. The inhibitory mechanisms of startle reflex were used as the measure of sensorimotor gating. It was evoked by a strong acoustic stimulus (106 dB SPL, 40 ms) which was preceded by the weaker similar signal (80 dB SPL, 20 ms). A stabilographic platform was used to measure sensorimotor gating. Results. Results of static posturography show that the postural sway caused by the reaction to a strong acoustic stimulus is significantly smaller when this stimulus is preceded by the signal of lower intensity (prepulse). Such assessment is only possible in eyes open conditions. Conclusions. Static posturography can be simple and effective method used for diagnosis of sensorimotor gating in humans. PMID:27314041

  2. Characteristics of acoustic wave from atmospheric nuclear explosions conducted at the USSR Test Sites

    NASA Astrophysics Data System (ADS)

    Sokolova, Inna

    2015-04-01

    Availability of the acoustic wave on the record of microbarograph is one of discriminate signs of atmospheric (surface layer of atmosphere) and contact explosions. Nowadays there is large number of air wave records from chemical explosions recorded by the IMS infrasound stations installed during recent decade. But there is small number of air wave records from nuclear explosions as air and contact nuclear explosions had been conducted since 1945 to 1962, before the Limited Test Ban Treaty was signed in 1963 (the treaty banning nuclear weapon tests in the atmosphere, in outer space and under water) by the Great Britain, USSR and USA. That time there was small number of installed microbarographs. First infrasound stations in the USSR appeared in 1954, and by the moment of the USSR collapse the network consisted of 25 infrasound stations, 3 of which were located on Kazakhstan territory - in Kurchatov (East Kazakhstan), in Borovoye Observatory (North Kazakhstan) and Talgar Observatory (Northern Tien Shan). The microbarograph of Talgar Observatory was installed in 1962 and recorded large number of air nuclear explosions conducted at Semipalatinsk Test Site and Novaya Zemlya Test Site. The epicentral distance to the STS was ~700 km, and to Novaya Zemlya Test Site ~3500 km. The historical analog records of the microbarograph were analyzed on the availability of the acoustic wave. The selected records were digitized, the database of acoustic signals from nuclear explosions was created. In addition, acoustic signals from atmospheric nuclear explosions conducted at the USSR Test Sites were recorded by analogue broadband seismic stations at wide range of epicentral distances, 300-3600 km. These signals coincide well by its form and spectral content with records of microbarographs and can be used for monitoring tasks and discrimination in places where infrasound observations are absent. Nuclear explosions which records contained acoustic wave were from 0.03 to 30 kt yield for

  3. Thick Films acoustic sensors devoted to MTR environment measurements. Thick Films acoustic sensors devoted to Material Testing Reactor environment measurements

    SciTech Connect

    Very, F.; Rosenkrantz, E.; Combette, P.; Ferrandis, J.Y.; Fourmentel, D.; Destouches, C.; Villard, J.F.

    2015-07-01

    The development of advanced instrumentation for in-pile experiments in Material Testing Reactor constitutes a main goal for the improvement of the nuclear fuel behavior knowledge. An acoustic method for fission gas release detection was tested with success during a first experiment called REMORA 3 in 2010 and 2011, and the results were used to differentiate helium and fission gas release kinetics under transient operating conditions. This experiment was lead at OSIRIS reactor (CEA Saclay, France). The maximal temperature on the sensor during the irradiation was about 150 deg. C. In this paper we present a thick film transducer produce by screen printing process. The screen printing of piezoelectric offers a wide range of possible applications for the development of acoustic sensors and piezoelectric structure for measurements in high temperature environment. We firstly produced a Lead Zirconate Titanate (PZT) based paste composed of Pz27 powder from Ferroperm, CF7575 glass, and organic solvent ESL 400. Likewise a Bismuth Titanate based paste synthesized in our laboratory was produced. With these inks we produced thick film up to 130 μm by screen printing process. Material properties characterizations of these thick-film resonators are essential for device design and applications. The piezoelectric coefficients d33 and pyro-electric P(T) coefficient are investigated. The highest P(T) and d33 are respectively 80 μC.m{sup -2}.K{sup -1} and 130 μC.N{sup -1} for the PZT transducer -which validates the fabrication process-. In view of the development of this transducer oriented for high temperature and irradiation environment, we investigated the electrical properties of the transducers for different ranges of frequencies and temperature - from 20 Hz up to 40 MHz between 30 and 400 deg. C. We highlight the evolution of the impedance response and piezoelectric parameters of screen printed piezoelectric structures on alumina. Shortly an irradiation will be realized in

  4. Evaluation of Acoustic Emission SHM of PRSEUS Composite Pressure Cube Tests

    NASA Technical Reports Server (NTRS)

    Horne, Michael R.; Madaras, Eric I.

    2013-01-01

    A series of tests of the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) pressure cube were conducted during third quarter 2011 at NASA Langley Research Center (LaRC) in the Combined Loads Test facility (COLTS). This is a report of the analysis of the Acoustic Emission (AE) data collected during those tests. The AE signals of the later tests are consistent with the final failure progression through two of the pressure cube panels. Calibration tests and damage precursor AE indications, from preliminary checkout pressurizations, indicated areas of concern that eventually failed. Hence those tests have potential for vehicle health monitoring.

  5. Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction.

    PubMed

    Wheeler, Marina G; Duncan, Erica; Davis, Michael

    2017-01-01

    Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Low startle rats show greater cocaine self-administration than high startle rats. Low startle may be a marker of a vulnerability to heightened cocaine-related behaviors in rats and similarly may be a marker of vulnerability to cocaine addiction in humans.

  6. Effect of facial self-resemblance on the startle response and subjective ratings of erotic stimuli in heterosexual men.

    PubMed

    Lass-Hennemann, Johanna; Deuter, Christian E; Kuehl, Linn K; Schulz, Andre; Blumenthal, Terry D; Schachinger, Hartmut

    2011-10-01

    Cues of kinship are predicted to increase prosocial behavior due to the benefits of inclusive fitness, but to decrease approach motivation due to the potential costs of inbreeding. Previous studies have shown that facial resemblance, a putative cue of kinship, increases prosocial behavior. However, the effects of facial resemblance on mating preferences are equivocal, with some studies finding that facial resemblance decreases sexual attractiveness ratings, while other studies show that individuals choose mates partly on the basis of similarity. To further investigate this issue, a psychophysiological measure of affective processing, the startle response, was used in this study, assuming that differences in approach motivation to erotic pictures will modulate startle. Male volunteers (n = 30) viewed 30 pictures of erotic female nudes while startle eyeblink responses were elicited by acoustic noise probes. The female nude pictures were digitally altered so that the face either resembled the male participant or another participant, or were not altered. Non-nude neutral pictures were also included. Importantly, the digital alteration was undetected by the participants. Erotic pictures were rated as being pleasant and clearly reduced startle eyeblink magnitude as compared to neutral pictures. Participants showed greater startle inhibition to self-resembling than to other-resembling or non-manipulated female nude pictures, but subjective pleasure and arousal ratings did not differ among the three erotic picture categories. Our data suggest that visual facial resemblance of opposite-sex nudes increases approach motivation in men, and that this effect was not due to their conscious evaluation of the erotic stimuli.

  7. STS-70 Discovery launch startling the birds

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Startled birds scatter as the stillness of a summer morning is broken by a giant's roar. The Space Shuttle Discovery thundered into space from launch Pad 39-B at 9:41:55:078 a.m. EDT. STS-70 is the 70th Shuttle flight overall, the 21st for Discovery (OV- 103), and the fourth Shuttle flight in 1995. On board for the nearly eight-day mission are a crew of five: Commander Terence 'Tom' Hendricks; Pilot Kevin R. Kregel; and Mission Specialists Nancy Jane Currie, Donald A. Thomas and Mary Ellen Weber. The crew's primary objective is to deploy the Tracking and Data Relay Satellite-G (TDRS-G), which will join a constellation of other TDRS spacecraft already on orbit.

  8. A modal test method using sound pressure transducers based on vibro-acoustic reciprocity

    NASA Astrophysics Data System (ADS)

    Zhu, W. D.; Liu, J. M.; Xu, Y. F.; Ying, H. Q.

    2014-06-01

    A modal test method that uses sound pressure transducers at fixed locations and an impact hammer roving over a test structure is developed in this work. Since sound pressure transducers are used, the current method deals with a coupled structural-acoustic system. Based on the vibro-acoustic reciprocity, the method is equivalent to one, where acoustic excitations at fixed locations are given and the resulting acceleration of the test structure is measured. The current method can eliminate mass loading due to use of accelerometers, which can destroy existence of repeated or close natural frequencies of a symmetric structure. It can also avoid effects of a nodal line of a mode and an inactive area of a local mode, and measure all the out-of-plane modes within a frequency range of interest, including global and local ones. The coupling between the structure and the acoustic field in a structural-acoustic system introduces asymmetry in the model formulation. An equivalent state space formulation is used for a damped structural-acoustic system and the associated eigenvalue problem is derived. The biorthonormality relations between the left and right eigenvectors and the relations between the structural and acoustic components in the left and right eigenvectors are proved. The frequency response functions associated with the current method are derived and their physical meanings are explained. The guidelines for using the current method, including the types of structures that are suitable for the method, the positions of the sound pressure transducers, and the orientation of the test structure relative to the transducers, are provided. Modal tests were carried out on an automotive disk brake using the traditional and current methods, where multiple accelerometers and microphones were used to measure its dynamic responses induced by impacts, respectively. The differences between the measured natural frequencies using the current method and those from the finite element

  9. Startle and blink reflex in high functioning autism.

    PubMed

    Erturk, Ozdem; Korkmaz, Baris; Alev, Gulce; Demirbilek, Veysi; Kiziltan, Meral

    2016-06-01

    An important clinical feature of autism is the presence of atypical responses to sensory stimuli. In this study, we investigated if high functioning autistic patients had abnormalities in the blink reflex and the startle reaction to auditory or somatosensory stimuli. Fourteen patients aged between 7 and 16 years were included in the study. We found a longer latency of the blink reflex, an increased duration and amplitude of the auditory startle reaction and a lower presence rate of the somatosensorial startle reaction in autistic patients. To better define the sensorial characteristics of the disease could improve the therapeutic management of children with autism spectrum disorder.

  10. Noise testing of an advanced design propeller in the Boeing transonic wind tunnel with and without test section acoustic treatment

    NASA Astrophysics Data System (ADS)

    Glover, B. M., Jr.; Plunkett, E. I.; Simcox, C. D.

    1984-10-01

    Noise tests using the NASA SR-6 advanced design propeller in the Boeing Transonic Wind Tunnel have recently been completed. Measurements were taken both with and without an acoustically treated test section. A wide range of helical tip speeds and power loadings were explored. Noise test techniques, previously not applied to advanced design propeller testing, have shown results indicating an increased level of confidence in the measured signatures. Typical results are presented along with recommendations for future noise tests and elementary empirical prediction methods for the SR-6.

  11. J-FLiC UAS Flights for Acoustic Testing Research

    NASA Technical Reports Server (NTRS)

    Motter, Mark A.; High, James W.

    2016-01-01

    The jet-powered flying testbed (J-FLiC) unmanned aircraft system (UAS) successfully completed twenty-six flights at Fort AP Hill, VA, from 27 August until September 3 2015, supporting tests of a microphone array system for aircraft noise measurement. The test vehicles, J-FLiC NAVY2 (N508NU), and J-FLiC 4 (N509NU), were flown under manual and autopiloted control in a variety of test conditions: clean at speeds ranging from 80 to 150 knots; and full landing configuration at speeds ranging from 50 to 95 knots. During the test campaign, autopilot capability was incrementally improved to ultimately provide a high degree of accuracy and repeatability of the critical test requirements for airspeed, altitude, runway alignment and position over the microphone array. Manual flights were performed for test conditions at the both ends of the speed envelope where autopiloted flight would have required flight beyond visual range and more extensive developmental work. The research objectives of the campaign were fully achieved. The ARMD Integrated Systems Research Program (ISRP) Environmentally Responsible Aviation (ERA) Project aims to develop the enabling capabilities/technologies that will allow prediction/reduction of aircraft noise. A primary measurement tool for ascertaining and characterizing empirically the effectiveness of various noise reduction technologies is a microphone phased array system. Such array systems need to be vetted and certified for operational use via field deployments and overflights of the array with test aircraft, in this case with sUAS aircraft such as J-FLiC.

  12. Wind Turbine Generator System Acoustic Noise Test Report for the Gaia Wind 11-kW Wind Turbine

    SciTech Connect

    Huskey, A.

    2011-11-01

    This report details the acoustic noise test conducted on the Gaia-Wind 11-kW wind turbine at the National Wind Technology Center. The test turbine is a two- bladed, downwind wind turbine with a rated power of 11 kW. The test turbine was tested in accordance with the International Electrotechnical Commission standard, IEC 61400-11 Ed 2.1 2006-11 Wind Turbine Generator Systems -- Part 11 Acoustic Noise Measurement Techniques.

  13. Aural Acoustic Stapedius-Muscle Reflex Threshold Procedures to Test Human Infants and Adults.

    PubMed

    Keefe, Douglas H; Feeney, M Patrick; Hunter, Lisa L; Fitzpatrick, Denis F

    2017-02-01

    Power-based procedures are described to measure acoustic stapedius-muscle reflex threshold and supra-threshold responses in human adult and infant ears at frequencies from 0.2 to 8 kHz. The stimulus set included five clicks in which four pulsed activators were placed between each pair of clicks, with each stimulus set separated from the next by 0.79 s to allow for reflex decay. Each click response was used to detect the presence of reflex effects across frequency that were elicited by a pulsed broadband-noise or tonal activator in the ipsilateral or contralateral test ear. Acoustic reflex shifts were quantified in terms of the difference in absorbed sound power between the initial baseline click and the later four clicks in each set. Acoustic reflex shifts were measured over a 40-dB range of pulsed activators, and the acoustic reflex threshold was objectively calculated using a maximum 10 likelihood procedure. To illustrate the principles underlying these new reflex tests, reflex shifts in absorbed sound power and absorbance are presented for data acquired in an adult ear with normal hearing and in two infant ears in the initial and follow-up newborn hearing screening exams, one with normal hearing and the other with a conductive hearing loss. The use of absorbed sound power was helpful in classifying an acoustic reflex shift as present or absent. The resulting reflex tests are in use in a large study of wideband clinical diagnosis and monitoring of middle-ear and cochlear function in infant and adult ears.

  14. Free jet feasibility study of a thermal acoustic shield concept for AST/VCE application-dual flow. Comprehensive data report. Volume 1: Test nozzles and acoustic data

    NASA Technical Reports Server (NTRS)

    Janardan, B. A.; Brausch, J. F.; Price, A. O.

    1984-01-01

    Acoustic and diagnostic data that were obtained to determine the influence of selected geometric and aerodynamic flow variables of coannular nozzles with thermal acoustic shields are summarized in this comprehensive data report. A total of 136 static and simulated flight acoustic test points were conducted with 9 scale-model nozzles The tested nozzles included baseline (unshielded), 180 deg shielded, and 360 deg shielded dual flow coannular plug configurations. The baseline configurations include a high radius ratio unsuppressed coannular plug nozzle and a coanuular plug nozzle and a coannular plug nozzle with a 20-chute outer stream suppressor. The tests were conducted at nozzle temperatures and pressure typical of operating conditions of variable cycle engine.

  15. Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

    NASA Technical Reports Server (NTRS)

    Liever, Peter A.; West, Jeffrey S.

    2016-01-01

    A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

  16. Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

    NASA Technical Reports Server (NTRS)

    Liever, Peter A.; West, Jeffrey S.; Harris, Robert E.

    2016-01-01

    A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate Discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured mesh Discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

  17. Effects of brain-derived and glial cell line-derived neurotrophic factors on startle response and disrupted prepulse inhibition in mice of DBA/2J inbred strain.

    PubMed

    Naumenko, Vladimir S; Bazovkina, Daria V; Morozova, Maryana V; Popova, Nina K

    2013-08-29

    Prepulse inhibition (PPI), the reduction in acoustic startle reflex when it is preceded by weak prepulse stimuli, is a measure of critical to normal brain functioning sensorimotor gating. PPI deficit was shown in a variety of psychiatric disorders including schizophrenia, and in DBA/2J mouse strain. In the current study, we examined the effects of brain-derived (BDNF) and glial cell line-derived (GDNF) neurotrophic factors on acoustic startle response and PPI in DBA/2J mice. It was found that BDNF (300 ng, i.c.v.) significantly increased amplitude of startle response and restored disrupted PPI in 7 days after acute administration. GDNF (800 ng, i.c.v.) did not produce significant alteration neither in amplitude of startle response nor in PPI in DBA/2J mice. The reversal effect of BDNF on PPI deficit was unusually long-lasting: significant increase in PPI was found 1.5 months after single acute BDNF administration. Long-term ameliorative effect BDNF on disrupted PPI suggested the implication of epigenetic mechanism in BDNF action on neurogenesis. BDNF rather than GDNF could be a perspective drug for the treatment of sensorimotor gating impairments.

  18. A closed-loop automatic control system for high-intensity acoustic test systems.

    NASA Technical Reports Server (NTRS)

    Slusser, R. A.

    1973-01-01

    Description of an automatic control system for high-intensity acoustic tests in reverberation chambers. Working in 14 one-third-octave bands from 50 to 1000 Hz, the desired sound pressure levels are set into the memory in the control system before the test. The control system then increases the sound pressure level in the reverberation chamber gradually in each of the one-third-octave bands until the level set in the memory is reached. This level is then maintained for the duration of the test. Additional features of the system are overtest protection, the capability of 'holding' the spectrum at any time, and the presence of a total test timer.

  19. Towards an ecological audiology: stereophonic listening chamber and acoustic environmental tests.

    PubMed

    Borg, E; Wilson, M; Samuelsson, E

    1998-01-01

    An acoustic laboratory for reproduction of speech and acoustic environments is presented along with two sound field tests. Its design has been inspired by the LEDE (Living End Dead End) principle for construction of radio and music control rooms. The equipment and the 12 loudspeakers can simultaneously reproduce several stereophonic and monophonic recordings. The interesting feature is that the delayed first reflex in the LEDE room allows for a realistic perception of the recording room. A preliminary presentation of two newly developed tests for sound field listening is given. In DSIN. Directional Speech In Noise, the JFC (just follow conversation) threshold for continuous discourse is determined in 12 directions in quiet and in noise from +/- 60 degrees azimuth. In SEIT (Sound Environmental Identification Test), stereophonic acoustic environments are presented and the subject is asked to identify specific components and to characterize each environment as closely as possible. Results from tests with normal hearing subjects and examples of results with hearing impaired subjects are presented. The potential of the technique for use in aural rehabilitation, functional definition of auditory communication and quality assessment of hearing aids is discussed. It is pointed out that the term ecological audiology is suitable for describing the interaction between the communicating individual and the environment in a broad sense.

  20. Acoustic Performance of an Advanced Model Turbofan in Three Aeroacoustic Test Facilities

    NASA Technical Reports Server (NTRS)

    Woodward, Richard P.; Hughes, Christopher E.

    2012-01-01

    A model advanced turbofan was acoustically tested in the NASA Glenn 9- by 15-Foot-Low-Speed Wind Tunnel (LSWT), and in two other aeroacoustic facilities. The Universal Propulsion Simulator (UPS) fan was designed and manufactured by the General Electric Aircraft Engines (GEAE) Company, and featured active core, as well as bypass, flow paths. The reference test configurations were with the metal, M4, rotor with hardwall and treated bypass flow ducts. The UPS fan was tested within an airflow at a Mach number of 0.20 (limited flow data were also acquired at a Mach number of 0.25) which is representative of aircraft takeoff and approach conditions. Comparisons were made between data acquired within the airflow (9x15 LSWT and German-Dutch Wind Tunnel (DNW)) and outside of a free jet (Boeing Low Speed Aero acoustic Facility (LSAF) and DNW). Sideline data were acquired on an 89-in. (nominal 4 fan diameters) sideline using the same microphone assembly and holder in the 9x15 LSWT and DNW facilities. These data showed good agreement for similar UPS operating conditions and configurations. Distortion of fan spectra tonal content through a free jet shear layer was documented, suggesting that in-flow acoustic measurements are required for comprehensive fan noise diagnostics. However, there was good agreement for overall sound power level (PWL) fan noise measurements made both within and outside of the test facility airflow.

  1. Acoustic testing of a supersonic tip speed fan with acoustic treatment and rotor casting slots. Quiet engine program scale model fan C

    NASA Technical Reports Server (NTRS)

    Kazin, S. B.

    1973-01-01

    Acoustic tests were conducted on a high tip speed (1550 ft/sec, 472.44 m/sec) single stage fan with varying amounts of wall acoustic treatment and with circumferential slots over the rotor blade tips. The slots were also tested with acoustic treatment placed behind the slots. The wall treatment results show that the inlet treatment is more effective at high fan speeds and aft duct treatment is more effective at low fan speeds. Maximum PNL's on a 200-foot (60.96 m) sideline show the untreated slots to have increased the rear radiated noise at approach. However, when the treatment was added to the slots inlet radiated noise was decreased, resulting in little change relative to the solid casing on an EPNL basis.

  2. Acoustic Emission Monitoring of the DC-XA Composite Liquid Hydrogen Tank During Structural Testing

    NASA Technical Reports Server (NTRS)

    Wilkerson, C.

    1996-01-01

    The results of acoustic emission (AE) monitoring of the DC-XA composite liquid hydrogen tank are presented in this report. The tank was subjected to pressurization, tensile, and compressive loads at ambient temperatures and also while full of liquid nitrogen. The tank was also pressurized with liquid hydrogen. AE was used to monitor the tank for signs of structural defects developing during the test.

  3. Structural Dynamic Assessment of the GN2 Piping System for NASA's New and Powerful Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    McNelis, Mark E.; Staab, Lucas D.; Akers, James C.; Hughes, WIlliam O.; Chang, Li, C.; Hozman, Aron D.; Henry, Michael W.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) has led the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC's Plum Brook Station in Sandusky, Ohio, USA from 2007-2011. SAIC-Benham has completed construction of a new reverberant acoustic test facility to support the future testing needs of NASA's space exploration program and commercial customers. The large Reverberant Acoustic Test Facility (RATF) is approximately 101,000 cu ft in volume and was designed to operate at a maximum empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world's known active reverberant acoustic test facilities. Initial checkout acoustic testing was performed on March 2011 by SAIC-Benham at test levels up to 161 dB OASPL. During testing, several branches of the gaseous nitrogen (GN2) piping system, which supply the fluid to the noise generating acoustic modulators, failed at their "t-junctions" connecting the 12 inch supply line to their respective 4 inch branch lines. The problem was initially detected when the oxygen sensors in the horn room indicated a lower than expected oxygen level from which was inferred GN2 leaks in the piping system. In subsequent follow up inspections, cracks were identified in the failed "t-junction" connections through non-destructive evaluation testing . Through structural dynamic modeling of the piping system, the root cause of the "t-junction" connection failures was determined. The structural dynamic assessment identified several possible corrective design improvements to the horn room piping system. The effectiveness of the chosen design repairs were subsequently evaluated in September 2011 during acoustic verification testing to 161 dB OASPL.

  4. Structural Dynamic Assessment of the GN2 Piping System for NASA's New and Powerful Reverberant Acoustic Test Facility

    NASA Technical Reports Server (NTRS)

    McNelis, Mark E.; Staab, Lucas D.; Akers, James C.; Hughes, William O.; Chang, Li C.; Hozman, Aron D.; Henry, Michael W.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) has led the design and build of the new world-class vibroacoustic test capabilities at the NASA GRC's Plum Brook Station in Sandusky, Ohio, USA from 2007 to 2011. SAIC-Benham has completed construction of a new reverberant acoustic test facility to support the future testing needs of NASA's space exploration program and commercial customers. The large Reverberant Acoustic Test Facility (RATF) is approximately 101,000 cubic feet in volume and was designed to operate at a maximum empty chamber acoustic overall sound pressure level (OASPL) of 163 dB. This combination of size and acoustic power is unprecedented amongst the world s known active reverberant acoustic test facilities. Initial checkout acoustic testing was performed on March 2011 by SAIC-Benham at test levels up to 161 dB OASPL. During testing, several branches of the gaseous nitrogen (GN2) piping system, which supply the fluid to the noise generating acoustic modulators, failed at their T-junctions connecting the 12 in. supply line to their respective 4 in. branch lines. The problem was initially detected when the oxygen sensors in the horn room indicated a lower than expected oxygen level from which was inferred GN2 leaks in the piping system. In subsequent follow up inspections, cracks were identified in the failed T-junction connections through non-destructive evaluation testing. Through structural dynamic modeling of the piping system, the root cause of the T-junction connection failures was determined. The structural dynamic assessment identified several possible corrective design improvements to the horn room piping system. The effectiveness of the chosen design repairs were subsequently evaluated in September 2011 during acoustic verification testing to 161 dB OASPL.

  5. A comparison of the acoustic and aerodynamic measurements of a model rotor tested in two anechoic wind tunnels

    NASA Technical Reports Server (NTRS)

    Boxwell, D. A.; Schmitz, F. H.; Splettstoesser, W. R.; Schultz, K. J.; Lewy, S.; Caplot, M.

    1986-01-01

    Two aeroacoustic facilities--the CEPRA 19 in France and the DNW in the Netherlands--are compared. The two facilities have unique acoustic characteristics that make them appropriate for acoustic testing of model-scale helicopter rotors. An identical pressure-instrumented model-scale rotor was tested in each facility and acoustic test results are compared with full-scale-rotor test results. Blade surface pressures measured in both tunnels were used to correlated nominal rotor operating conditions in each tunnel, and also used to assess the steadiness of the rotor in each tunnel's flow. In-the-flow rotor acoustic signatures at moderate forward speeds (35-50 m/sec) are presented for each facility and discussed in relation to the differences in tunnel geometries and aeroacoustic characteristics. Both reports are presented in appendices to this paper. ;.);

  6. Vibro-Acoustic Response of Buildings Due to Sonic Boom Exposure: July 2007 Field Test

    NASA Technical Reports Server (NTRS)

    Klos, Jacob

    2008-01-01

    During the month of July 2007, a series of structural response measurements were made on a house on Edwards Air Force Base (EAFB) property that was exposed to sonic booms of various amplitudes. The purpose of this report is to document the measurements that were made, the structure on which they were made, the conditions under which they were made, the sensors and other hardware that were used, and the data that were collected. To that end, Chapter 2 documents the house, its location, the physical layout of the house, the surrounding area, and summarizes the transducers placed in and around the house. Chapter 3 details the sensors and other hardware that were placed in the house during the experiment. In addition, day-to-day variations of hardware configurations and transducer calibrations are documented in Chapter 3. Chapter 4 documents the boom generation process, flight conditions, and ambient weather conditions during the test days. Chapter 5 includes information about sub-experiments that were performed to characterize the vibro-acoustic response of the structure, the acoustic environment inside the house, and the acoustic environment outside the house. Chapter 6 documents the data format and presents examples of reduced data that were collected during the test days.

  7. Perinatal exposure to the selective serotonin reuptake inhibitor citalopram alters spatial learning and memory, anxiety, depression, and startle in Sprague-Dawley rats.

    PubMed

    Sprowles, Jenna L N; Hufgard, Jillian R; Gutierrez, Arnold; Bailey, Rebecca A; Jablonski, Sarah A; Williams, Michael T; Vorhees, Charles V

    2016-11-01

    Selective serotonin reuptake inhibitors (SSRIs) block the serotonin (5-HT) reuptake transporter (SERT) and increase synaptic 5-HT. 5-HT is also important in brain development; hence when SSRIs are taken during pregnancy there exists the potential for these drugs to affect CNS ontogeny. Prenatal SSRI exposure has been associated with an increased prevalence of autism spectrum disorder (ASD), and peripheral 5-HT is elevated in some ASD patients. Perinatal SSRI exposure in rodents has been associated with increased depression and anxiety-like behavior, decreased sociability, and impaired learning in the offspring, behaviors often seen in ASD. The present study investigated whether perinatal exposure to citalopram causes persistent neurobehavioral effects. Gravid Sprague-Dawley rats were assigned to two groups and subcutaneously injected twice per day with citalopram (10mg/kg; Cit) or saline (Sal) 6h apart on embryonic day (E)6-21, and then drug was given directly to the pups after delivery from postnatal day (P)1-20. Starting on P60, one male/female from each litter was tested in the Cincinnati water maze (CWM) and open-field before and after MK-801. A second pair from each litter was tested in the Morris water maze (MWM) and open-field before and after (+)-amphetamine. A third pair was tested as follows: elevated zero-maze, open-field, marble burying, prepulse inhibition of acoustic startle, social preference, and forced swim. Cit-exposed rats were impaired in the MWM during acquisition and probe, but not during reversal, shift, or cued trials. Cit-exposed rats also showed increased marble burying, decreased time in the center of the open-field, decreased latency to immobility in forced swim, and increased acoustic startle across prepulse intensities with no effects on CWM. The results are consistent with citalopram inducing several ASD-like effects. The findings add to concerns about use of SSRIs during pregnancy. Further research on different classes of

  8. Force Limiting Vibration Tests Evaluated from both Ground Acoustic Tests and FEM Simulations of a Flight Like Vehicle System Assembly

    NASA Technical Reports Server (NTRS)

    Smith, Andrew; LaVerde, Bruce; Waldon, James; Hunt, Ron

    2014-01-01

    Marshall Space Flight Center has conducted a series of ground acoustic tests with the dual goals of informing analytical judgment, and validating analytical methods when estimating vibroacoustic responses of launch vehicle subsystems. The process of repeatedly correlating finite element-simulated responses with test-measured responses has assisted in the development of best practices for modeling and post-processing. In recent work, force transducers were integrated to measure interface forces at the base of avionics box equipment. Other force data was indirectly measured using strain gauges. The combination of these direct and indirect force measurements has been used to support and illustrate the advantages of implementing the Force Limiting approach for equipment qualification tests. The comparison of force response from integrated system level tests to measurements at the same locations during component level vibration tests provides an excellent illustration. A second comparison of the measured response cases from the system level acoustic tests to finite element simulations has also produced some principles for assessing the suitability of Finite Element Models (FEMs) for making vibroacoustics estimates. The results indicate that when FEM models are employed to guide force limiting choices, they should include sufficient detail to represent the apparent mass of the system in the frequency range of interest.

  9. Variants near CCK receptors are associated with electrophysiological responses to prepulse startle stimuli in a Mexican American cohort

    PubMed Central

    Norden-Krichmar, Trina M.; Gizer, Ian R.; Phillips, Evelyn; Wilhelmsen, Kirk C.; Schork, Nicholas J.; Ehlers, Cindy L.

    2016-01-01

    Neurophysiological measurements of the response to prepulse and startle stimuli have been suggested to represent an important endophenotype for both substance dependence and other select psychiatric disorders. We have previously shown, in young adult Mexican Americans (MA), that presentation of a short delay acoustic prepulse, prior to the startle stimuli can elicit a late negative component at about 400 msec (N4S), in the event-related potential (ERP), recorded from frontal cortical areas. In the present study we investigated whether genetic factors associated with this endophenotype could be identified. The study included 420 (age 18 – 30 years) MA men (n=170) and women (n=250). DNA was genotyped using an Affymetrix Axiom Exome1A chip. An association analysis revealed that the CCKAR and CCKBR (cholecystokinin A and B receptor) genes each had a nearby variant that showed suggestive significance with the amplitude of the N4S component to prepulse stimuli. The neurotransmitter cholecystokinin (CCK), along with its receptors, CCKAR and CCKBR, have been previously associated with psychiatric disorders, suggesting that variants near these genes may play a role in the prepulse/startle response in this cohort. PMID:26608796

  10. Acoustic emission on flexural fracture test of SiC/Al composites

    NASA Astrophysics Data System (ADS)

    Sofue, Yasushi; Ogawa, Akinori

    1990-11-01

    Fracture behavior of SiC/Al composites was investigated using three point flexural tests with Acoustic Emission (AE) measurement. Flexural tests were conducted for four different types of ply specimens (0 deg unidirectional, 0 deg unidirectional, 0 deg/90 deg ply, and +/- 45 deg ply) of each of the composite materials and the specimen of 6061 aluminum alloy. The AE amplitude was above 8 dB for the fiber breakage of the 0 deg unidirectional ply and 0 deg/90 deg ply specimen, while the 0 deg unidirectional ply and the +/- 45 deg ply specimen produced an AE amplitude below 72 dB for the interlaminar and interface fracture mode.

  11. Recognition test for an open set of talkers represented by their acoustic parameters

    NASA Astrophysics Data System (ADS)

    Federico, A.; Ibba, G.; Paoloni, A.; Ragona, R.

    1981-03-01

    A method based on a precise statistical formulation is presented which allows the use of a limited set of acoustic parameters for the recognition of the speaker in an open test. A number of speech realizations are collected for a group of different speakers. A second collection is made of utterances to be compared with the known speakers. In the general case a new utterance may not belong to any of the talkers referred to the test. Error of false identification and rejection is estimated as a measure of procedure effectiveness. Some considerations are made about the feasibility of the proposed method in the field practice of speaker recognition.

  12. Acoustic Performance Of New Designs Of Traffic Noise Barriers: Full Scale Tests

    NASA Astrophysics Data System (ADS)

    Watts, G. R.; Crombie, D. H.; Hothersall, D. C.

    1994-10-01

    Full scale tests of acoustical performance are reported on a range of promising traffic noise barrier shapes which had previously been identified by mathematical and scale modelling work. The designs chosen for testing were T-shaped, multiple edge barriers and double barriers. A test facility was established at the Transport Research Laboratory (TRL) in order to examine effectiveness under full scale conditions. This consisted of a 20 m length of noise barrier with interchangeable barrier panels, a large flat asphalt surface and a transportable speaker system capable of sufficient output to represent typical traffic noise. Screening performance was measured up to 80 m behind the barriers over a flat grassland area and at heights above the ground of 1·5 and 4·5 m. It was concluded that the average increase in acoustic screening of 2 m high T-shaped, multiple edge and double barriers compared with a simple plane reflecting barrier of identical overall height ranged from 1·4 to 3·6dB(A) depending on detailed design. It was suggested that a full scale test of a promising design should be carried out at a suitable highway location in order to validate fully these test results.

  13. Preliminary Analysis of Acoustic Measurements from the NASA-Gulfstream Airframe Noise Flight Test

    NASA Technical Reports Server (NTRS)

    Khorrami, Mehdi R.; Lockhard, David D.; Humphreys, Willliam M.; Choudhari, Meelan M.; Van De Ven, Thomas

    2008-01-01

    The NASA-Gulfstream joint Airframe Noise Flight Test program was conducted at the NASA Wallops Flight Facility during October, 2006. The primary objective of the AFN flight test was to acquire baseline airframe noise data on a regional jet class of transport in order to determine noise source strengths and distributions for model validation. To accomplish this task, two measuring systems were used: a ground-based microphone array and individual microphones. Acoustic data for a Gulfstream G550 aircraft were acquired over the course of ten days. Over twenty-four test conditions were flown. The test matrix was designed to provide an acoustic characterization of both the full aircraft and individual airframe components and included cruise to landing configurations. Noise sources were isolated by selectively deploying individual components (flaps, main landing gear, nose gear, spoilers, etc.) and altering the airspeed, glide path, and engine settings. The AFN flight test program confirmed that the airframe is a major contributor to the noise from regional jets during landing operations. Sound pressure levels from the individual microphones on the ground revealed the flap system to be the dominant airframe noise source for the G550 aircraft. The corresponding array beamform maps showed that most of the radiated sound from the flaps originates from the side edges. Using velocity to the sixth power and Strouhal scaling of the sound pressure spectra obtained at different speeds failed to collapse the data into a single spectrum. The best data collapse was obtained when the frequencies were left unscaled.

  14. Acoustic emission monitoring of a wind turbine blade during a fatigue test

    SciTech Connect

    Beattie, A.G.

    1997-01-01

    A fatigue test of a wind turbine blade was conducted at the National Renewable Energy Laboratory in the fall of 1994. Acoustic emission monitoring of the test was performed, starting with the second loading level. The acoustic emission data indicated that this load exceeded the strength of the blade. From the first cycle at the new load, an oil can type of deformation occurred in two areas of the upper skin of the blade. One of these was near the blade root and the other was about the middle of the tested portion of the blade. The emission monitoring indicated that no damage was taking place in the area near the root, but in the deforming area near the middle of the blade, damage occurred from the first cycles at the higher load. The test was stopped after approximately one day and the blade was declared destroyed, although no gross damage had occurred. Several weeks later the test was resumed, to be continued until gross damage occurred. The upper skin tore approximately one half hour after the cycling was restarted.

  15. Comparison of Modal Analysis Methods Applied to a Vibro-Acoustic Test Article

    NASA Technical Reports Server (NTRS)

    Pritchard, Jocelyn; Pappa, Richard; Buehrle, Ralph; Grosveld, Ferdinand

    2001-01-01

    Modal testing of a vibro-acoustic test article referred to as the Aluminum Testbed Cylinder (ATC) has provided frequency response data for the development of validated numerical models of complex structures for interior noise prediction and control. The ATC is an all aluminum, ring and stringer stiffened cylinder, 12 feet in length and 4 feet in diameter. The cylinder was designed to represent typical aircraft construction. Modal tests were conducted for several different configurations of the cylinder assembly under ambient and pressurized conditions. The purpose of this paper is to present results from dynamic testing of different ATC configurations using two modal analysis software methods: Eigensystem Realization Algorithm (ERA) and MTS IDEAS Polyreference method. The paper compares results from the two analysis methods as well as the results from various test configurations. The effects of pressurization on the modal characteristics are discussed.

  16. Mechanical design and vibro-acoustic testing of ultrathin carbon foils for a spacecraft instrument

    SciTech Connect

    Bernardin, John D; Baca, Allen G

    2009-01-01

    IBEX-Hi is an electrostatic analyzer spacecraft instrument designed to measure the energy and flux distribution of energetic neutral atoms (ENAs) emanating from the interaction zone between the Earth's solar system and the Milky Way galaxy. A key element to this electro-optic instrument is an array of fourteen carbon foils that are used to ionize the ENAs. The foils are comprised of an ultrathin (50-100 {angstrom} thick) layer of carbon suspended across the surface of an electroformed Nickel wire screen, which in turn is held taught by a metal frame holder. The electro formed orthogonal screen has square wire elements, 12.7 {micro}m thick, with a pitch of 131.1 wires/cm. Each foil holder has an open aperture approximately 5 cm by 2.5 cm. Designing and implementing foil holders with such a large surface area has not been attempted for spaceflight in the past and has proven to be extremely challenging. The delicate carbon foils are subject to fatigue failure from the large acoustic and vibration loads that they will be exposed to during launch of the spacecraft. This paper describes the evolution of the foil holder design from previous space instrument applications to a flight-like IBEX-Hi prototype. Vibro-acoustic qualification tests of the IBEX-Hi prototype instrument and the resulting failure of several foils are summarized. This is followed by a discussion of iterative foil holder design modifications and laser vibrometer modal testing to support future fatigue failure analyses, along with additional acoustic testing of the IBEX-Hi prototype instrument. The results of these design and testing activities are merged and the resulting flight-like foil holder assembly is proposed.

  17. Characterisation and testing of the KM3NeT acoustic positioning system

    NASA Astrophysics Data System (ADS)

    Viola, S.; Simeone, F.; Saldaña, M.

    2016-04-01

    In underwater neutrino telescopes, the search of point-like sources through the Cherenkov detection technique requires a precise knowledge of the positions of thousands of optical sensors, spread in a volume of a few cubic kilometres. In KM3NeT the optical sensors are hosted in 700 m high semi-rigid structures, called detection units, which move under the effects of underwater currents. These movements are continuously monitored through an underwater positioning system based on acoustic emitters and receivers. In this work, the tests performed on the key elements of the positioning system are presented.

  18. Digital servo control of random sound test excitation. [in reverberant acoustic chamber

    NASA Technical Reports Server (NTRS)

    Nakich, R. B. (Inventor)

    1974-01-01

    A digital servocontrol system for random noise excitation of a test object in a reverberant acoustic chamber employs a plurality of sensors spaced in the sound field to produce signals in separate channels which are decorrelated and averaged. The average signal is divided into a plurality of adjacent frequency bands cyclically sampled by a time division multiplex system, converted into digital form, and compared to a predetermined spectrum value stored in digital form. The results of the comparisons are used to control a time-shared up-down counter to develop gain control signals for the respective frequency bands in the spectrum of random sound energy picked up by the microphones.

  19. Estimation of respiratory rate and heart rate during treadmill tests using acoustic sensor.

    PubMed

    Popov, B; Sierra, G; Telfort, V; Agarwal, R; Lanzo, V

    2005-01-01

    The objective was to test the robustness of an acoustic method to estimate respiratory rates (RR) during treadmill test. The accuracy was assessed by the comparison with simultaneous estimates from a capnograph, using as a common reference a pneumotachometer. Eight subjects without any pulmonary disease were enrolled. Tracheal sounds were acquired using a contact piezoelectric sensor placed on the subject's throat and analyzed using a combined investigation of the sound envelope and frequency content. The capnograph and pneumotachometer were coupled to a face mask worn by the subjects. There was a strong linear correlation between all three methods (r2ranged from 0.8 to 0.87), and the SEE ranged from 1.97 to 2.36. As a conclusion, the accuracy of the respiratory rate estimated from tracheal sounds on adult subjects during treadmill stress test was comparable to the accuracy of a commercial capnograph. The heart rate (HR) estimates can also be derived from carotid pulse using the same single sensor placed on the subject's throat. Compared to the pulse oximeter the results show an agreement of acoustic method with r2=0.76 and SEE = 3.51.

  20. Acoustic flight tests of rotorcraft noise-abatement approaches using local differential GPS guidance

    NASA Technical Reports Server (NTRS)

    Chen, Robert T. N.; Hindson, William S.; Mueller, Arnold W.

    1995-01-01

    This paper presents the test design, instrumentation set-up, data acquisition, and the results of an acoustic flight experiment to study how noise due to blade-vortex interaction (BVI) may be alleviated. The flight experiment was conducted using the NASA/Army Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) research helicopter. A Local Differential Global Positioning System (LDGPS) was used for precision navigation and cockpit display guidance. A laser-based rotor state measurement system on board the aircraft was used to measure the main rotor tip-path-plane angle-of-attack. Tests were performed at Crows Landing Airfield in northern California with an array of microphones similar to that used in the standard ICAO/FAA noise certification test. The methodology used in the design of a RASCAL-specific, multi-segment, decelerating approach profile for BVI noise abatement is described, and the flight data pertaining to the flight technical errors and the acoustic data for assessing the noise reduction effectiveness are reported.

  1. Acoustic Modifications of the Ames 40x80 Foot Wind Tunnel and Test Techniques for High-Speed Research Model Testing

    NASA Technical Reports Server (NTRS)

    Soderman, Paul T.; Olson, Larry (Technical Monitor)

    1995-01-01

    The NFAC 40- by 80- Foot Wind Tunnel at Ames is being refurbished with a new, deep acoustic lining in the test section which will make the facility nearly anechoic over a large frequency range. The modification history, key elements, and schedule will be discussed. Design features and expected performance gains will be described. Background noise reductions will be summarized. Improvements in aeroacoustic research techniques have been developed and used recently at NFAC on several wind tunnel tests of High Speed Research models. Research on quiet inflow microphones and struts will be described. The Acoustic Survey Apparatus in the 40x80 will be illustrated. A special intensity probe was tested for source localization. Multi-channel, high speed digital data acquisition is now used for acoustics. And most important, phased microphone arrays have been developed and tested which have proven to be very powerful for source identification and increased signal-to-noise ratio. Use of these tools for the HEAT model will be illustrated. In addition, an acoustically absorbent symmetry plane was built to satisfy the HEAT semispan aerodynamic and acoustic requirements. Acoustic performance of that symmetry plane will be shown.

  2. Acoustic specifications for the design of jet engine test facilities on an airbase

    SciTech Connect

    Strumpf, F.M.

    1982-01-01

    The use of engine run up test arrangements was common in Israeli air-bases since the forties, when engines for the Mustang, Mosquito, Harward and other propellor powered planes were used. The era of jet engine propulsion boosted the noise levels, and the use of fighters with afterburners in the new engines of the 80's brought it up to unbearable levels. Thus, the growth of the Israeli Air Force demanded the use of efficient noise suppression devices. These were divided into engine run-up noise suppressors, and aircraft noise suppessors (Hush Houses). For both of the bove ground arrangements, acoustic specifications had to be given. They were, as well as design goals for the manufacturers, also needed to restrict noise levels on the air-base as well as its surroundings. The acoustic specifications discussed are based on measured data, and permitted noise levels in the homes on the base being as far as 2500 meters from the engine exhaust silencer. For the special air-base discussed, various criteria were tested, including US Military Specifications, none of which were acceptable, and a special specification was therefore prepared.

  3. Design, fabrication and acoustic tests of a 36 inch (0.914 meter) statorless turbotip fan

    NASA Technical Reports Server (NTRS)

    Smith, E. G.; Stempert, D. L.; Uhl, W. R.

    1975-01-01

    The LF336/E is a 36 inch (0.914 meter) diameter fan designed to operate in a rotor-alone configuration. Design features required for modification of the existing LF336/A rotor-stator fan into the LF336/E statorless fan configuration are discussed. Tests of the statorless fan identified an aerodynamic performance deficiency due to inaccurate accounting of the fan exit swirl during the aerodynamic design. This performance deficiency, related to fan exit static pressure levels, produced about a 20 percent thrust loss. A study was then conducted for further evaluation of the fan exit flow fields typical of statorless fan systems. This study showed that through proper selection of fan design variables such as pressure ratio, radius ratio, and swirl distributions, performance of a statorless fan configuration could be improved with levels of thrust approaching the conventional rotor-stator fan system. Acoustic measurements were taken for the statorless fan system at both GE and NASA, and when compared to other lift fan systems, showed noise levels comparable to the quietest lift fan configuration which included rotor-stator spacing and acoustic treatment. The statorless fan system was also used to determine effects of rotor leading edge serrations on noise generations. A cascade test program identified the serration geometry based on minimum pressure losses, wake turbulence levels and noise generations.

  4. Acoustic interactions between an altitude test facility and jet engine plumes: Theory and experiments

    NASA Technical Reports Server (NTRS)

    Ahuja, K. K.; Jones, R. R., III; Tam, C. K.; Massey, K. C.; Fleming, A. J.

    1992-01-01

    The overall objective of the described effort was to develop an understanding of the physical mechanisms involved in the flow/acoustic interactions experienced in full-scale altitude engine test facilities. This is done by conducting subscale experiments and through development of a theoretical model. Model cold jet experiments with an axisymmetric convergent nozzle are performed in a test setup that stimulates a supersonic jet exhausting into a cylindrical diffuser. The measured data consist of detailed flow visualization data and acoustic spectra for a free and a ducted plume. It is shown that duct resonance is most likely responsible by theoretical calculations. Theoretical calculations also indicate that the higher discrete tones observed in the measurements are related to the screech phenomena. Limited experiments on the sensitivity of a free 2-D, C-D nozzle to externally imposed sound are also presented. It is shown that a 2-D, C-D nozzle with a cutback is less excitable than a 2-D C-D nozzle with no cutback. At a pressure ratio of 1.5 unsteady separation from the diverging walls of the nozzle is noticed. This separation switches from one wall to the opposite wall thus providing an unsteady deflection of the plume. It is shown that this phenomenon is related to the venting provided by the cutback section.

  5. Test-Anchored Vibration Response Predictions for an Acoustically Energized Curved Orthogrid Panel with Mounted Components

    NASA Technical Reports Server (NTRS)

    Frady, Gregory P.; Duvall, Lowery D.; Fulcher, Clay W. G.; Laverde, Bruce T.; Hunt, Ronald A.

    2011-01-01

    A rich body of vibroacoustic test data was recently generated at Marshall Space Flight Center for a curved orthogrid panel typical of launch vehicle skin structures. Several test article configurations were produced by adding component equipment of differing weights to the flight-like vehicle panel. The test data were used to anchor computational predictions of a variety of spatially distributed responses including acceleration, strain and component interface force. Transfer functions relating the responses to the input pressure field were generated from finite element based modal solutions and test-derived damping estimates. A diffuse acoustic field model was employed to describe the assumed correlation of phased input sound pressures across the energized panel. This application demonstrates the ability to quickly and accurately predict a variety of responses to acoustically energized skin panels with mounted components. Favorable comparisons between the measured and predicted responses were established. The validated models were used to examine vibration response sensitivities to relevant modeling parameters such as pressure patch density, mesh density, weight of the mounted component and model form. Convergence metrics include spectral densities and cumulative root-mean squared (RMS) functions for acceleration, velocity, displacement, strain and interface force. Minimum frequencies for response convergence were established as well as recommendations for modeling techniques, particularly in the early stages of a component design when accurate structural vibration requirements are needed relatively quickly. The results were compared with long-established guidelines for modeling accuracy of component-loaded panels. A theoretical basis for the Response/Pressure Transfer Function (RPTF) approach provides insight into trends observed in the response predictions and confirmed in the test data. The software modules developed for the RPTF method can be easily adapted for

  6. Testing the effectiveness of an acoustic deterrent for gray whales along the Oregon coast

    SciTech Connect

    Lagerquist, Barbara; Winsor, Martha; Mate, Bruce

    2012-12-31

    This study was conducted to determine whether a low-powered sound source could be effective at deterring gray whales from areas that may prove harmful to them. With increased interest in the development of marine renewal energy along the Oregon coast the concern that such development may pose a collision or entanglement risk for gray whales. A successful acoustic deterrent could act as a mitigation tool to prevent harm to whales from such risks. In this study, an acoustic device was moored on the seafloor in the pathway of migrating gray whales off Yaquina Head on the central Oregon coast. Shore-based observers tracked whales with a theodolite (surveyor’s tool) to accurately locate whales as they passed the headland. Individual locations of different whales/whale groups as well as tracklines of the same whale/whale groups were obtained and compared between times with the acoustic device was transmitting and when it was off. Observations were conducted on 51 d between January 1 and April 15, 2012. A total of 143 individual whale locations were collected for a total of 243 whales, as well as 57 tracklines for a total of 142 whales. Inclement weather and equipment problems resulted in very small sample sizes, especially during experimental periods, when the device was transmitting. Because of this, the results of this study were inconclusive. We feel that another season of field testing is warranted to successfully test the effectiveness of the deterrent, but recommend increasing the zone of influence to 3 km to ensure the collection of adequate sample sizes. Steps have been taken to acquire the necessary federal research permit modification to authorize the increased zone of influence and to modify the acoustic device for the increased power. With these changes we are confident we will be able to determine whether the deterrent is effective at deflecting gray whales. A successful deterrent device may serve as a valuable mitigation tool to protect gray whales, and

  7. Laboratory Testing of Acoustic Tomography in Rock Samples Using Regularization of Incomplete Data

    NASA Astrophysics Data System (ADS)

    Li, C.; Nowack, R. L.; Pyrak-Nolte, L. J.

    2002-12-01

    Seismic tomography is an important exploration method because it has been shown that it can determine subsurface structures from surface measurements. In the field, it is often difficult to design a dense tomographic coverage. However, for rock samples in the laboratory, it is possible to design tomographic experiments that are repeatable and have uniform ray coverage. In this study, we performed a series of tomographic experiments in the laboratory on synthetic sediments with known structures. In these tomographic experiments, glass beads saturated with de-ionized water were used as the water-saturated unconsolidated synthetic background sediments. The synthetic sediments were packed in a plastic cylindrical container with a diameter of 220 mm. Tomographic experiments were set up to measure transmitted acoustic waves through the sediment samples from multiple directions. The acoustic tomographic imaging system we used is composed of an oscilloscope, two computer-controlled rotary stages, and two water-coupled point wave transducers with a central frequency of 1 MHz. One transducer is used as a source to send out acoustic signals, the other is used to receive the acoustic signals after the signals have passed through the sample. At each source-receiver location, a waveform is recorded. The recorded data can then be used to develop useful protocols for the field seismic tomographic design, acquisition and interpretation. We recorded datasets with varying locations for the sources and receivers, and used this to tomographically reconstruct the laboratory geometries. We simulated variable non-uniform ray geometries using partial data reconstructions. The partial data can then be used to test different techniques for dealing with ill-posed problems. Because the incomplete datasets alone cannot completely resolve the model, a priori information and an appropriate regularization are necessary to obtain stable solutions. With the datasets recorded in the laboratory we can

  8. Developmental lead exposure causes startle response deficits in zebrafish.

    PubMed

    Rice, Clinton; Ghorai, Jugal K; Zalewski, Kathryn; Weber, Daniel N

    2011-10-01

    Lead (Pb(2+)) exposure continues to be an important concern for fish populations. Research is required to assess the long-term behavioral effects of low-level concentrations of Pb(2+) and the physiological mechanisms that control those behaviors. Newly fertilized zebrafish embryos (<2h post fertilization; hpf) were exposed to one of three concentrations of lead (as PbCl(2)): 0, 10, or 30 nM until 24 hpf. (1) Response to a mechanosensory stimulus: Individual larvae (168 hpf) were tested for response to a directional, mechanical stimulus. The tap frequency was adjusted to either 1 or 4 taps/s. Startle response was recorded at 1000 fps. Larvae responded in a concentration-dependent pattern for latency to reaction, maximum turn velocity, time to reach V(max) and escape time. With increasing exposure concentrations, a larger number of larvae failed to respond to even the initial tap and, for those that did respond, ceased responding earlier than control larvae. These differences were more pronounced at a frequency of 4 taps/s. (2) Response to a visual stimulus: Fish, exposed as embryos (2-24 hpf) to Pb(2+) (0-10 μM) were tested as adults under low light conditions (≈ 60 μW/m(2)) for visual responses to a rotating black bar. Visual responses were significantly degraded at Pb(2+) concentrations of 30 nM. These data suggest that zebrafish are viable models for short- and long-term sensorimotor deficits induced by acute, low-level developmental Pb(2+) exposures.

  9. Effects of the psychotomimetic benzomorphan N-allylnormetazocine (SKF 10,047) on prepulse inhibition of startle in mice.

    PubMed

    Halberstadt, Adam L; Hyun, James; Ruderman, Michael A; Powell, Susan B

    2016-09-01

    N-allylnormetazocine (NANM; SKF 10,047) is a benzomorphan opioid that produces psychotomimetic effects. (+)-NANM is the prototypical agonist for the sigma-1 (σ1) receptor, and there is a widespread belief that the hallucinogenic effects of NANM and other benzomorphan derivatives are mediated by interactions with σ1 sites. However, NANM is also an agonist at the κ opioid receptor (KOR) and binds to the PCP site located within the channel pore of the NMDA receptor, interactions that could potentially contribute to the effects of NANM. NMDA receptor antagonists such as phencyclidine (PCP) and ketamine are known to disrupt prepulse inhibition (PPI) of acoustic startle, a measure of sensorimotor gating, in rodents. We recently found that racemic NANM disrupts PPI in rats, but it is not clear whether the effect is mediated by blockade of the NMDA receptor, or alternatively whether interactions with KOR and σ1 receptors are involved. The present studies examined whether NANM and its stereoisomers alter PPI in C57BL/6J mice, and tested whether the effects on PPI are mediated by KOR or σ1 receptors. Racemic NANM produced a dose-dependent disruption of PPI (3-30mg/kg SC). (+)-NANM also disrupted PPI, whereas (-)-NANM was ineffective. Pretreatment with the selective KOR antagonist nor-binaltorphimine (10mg/kg SC) or the selective σ1 antagonist NE-100 (1mg/kg IP) failed to attenuate the reduction in PPI produced by racemic NANM. We also found that the selective KOR agonist (-)-U-50,488H (10-40mg/kg SC) had no effect on PPI. These findings confirm that NANM reduces sensorimotor gating in rodents, and indicate that the effect is mediated by interactions with the PCP receptor and not by activation of KOR or σ1 receptors. This observation is consistent with evidence indicating that the σ1 receptor is not linked to hallucinogenic or psychotomimetic effects.

  10. Computational Fluid Dynamics Study on the Effects of RATO Timing on the Scale Model Acoustic Test

    NASA Technical Reports Server (NTRS)

    Nielsen, Tanner; Williams, B.; West, Jeff

    2015-01-01

    The Scale Model Acoustic Test (SMAT) is a 5% scale test of the Space Launch System (SLS), which is currently being designed at Marshall Space Flight Center (MSFC). The purpose of this test is to characterize and understand a variety of acoustic phenomena that occur during the early portions of lift off, one being the overpressure environment that develops shortly after booster ignition. The SLS lift off configuration consists of four RS-25 liquid thrusters on the core stage, with two solid boosters connected to each side. Past experience with scale model testing at MSFC (in ER42), has shown that there is a delay in the ignition of the Rocket Assisted Take Off (RATO) motor, which is used as the 5% scale analog of the solid boosters, after the signal to ignite is given. This delay can range from 0 to 16.5ms. While this small of a delay maybe insignificant in the case of the full scale SLS, it can significantly alter the data obtained during the SMAT due to the much smaller geometry. The speed of sound of the air and combustion gas constituents is not scaled, and therefore the SMAT pressure waves propagate at approximately the same speed as occurs during full scale. However, the SMAT geometry is much smaller allowing the pressure waves to move down the exhaust duct, through the trench, and impact the vehicle model much faster than occurs at full scale. To better understand the effect of the RATO timing simultaneity on the SMAT IOP test data, a computational fluid dynamics (CFD) analysis was performed using the Loci/CHEM CFD software program. Five different timing offsets, based on RATO ignition delay statistics, were simulated. A variety of results and comparisons will be given, assessing the overall effect of RATO timing simultaneity on the SMAT overpressure environment.

  11. Test-Anchored Vibration Response Predictions for an Acoustically Energized Curved Orthogrid Panel with Mounted Components

    NASA Technical Reports Server (NTRS)

    Frady, Gregory P.; Duvall, Lowery D.; Fulcher, Clay W. G.; Laverde, Bruce T.; Hunt, Ronald A.

    2011-01-01

    rich body of vibroacoustic test data was recently generated at Marshall Space Flight Center for component-loaded curved orthogrid panels typical of launch vehicle skin structures. The test data were used to anchor computational predictions of a variety of spatially distributed responses including acceleration, strain and component interface force. Transfer functions relating the responses to the input pressure field were generated from finite element based modal solutions and test-derived damping estimates. A diffuse acoustic field model was applied to correlate the measured input sound pressures across the energized panel. This application quantifies the ability to quickly and accurately predict a variety of responses to acoustically energized skin panels with mounted components. Favorable comparisons between the measured and predicted responses were established. The validated models were used to examine vibration response sensitivities to relevant modeling parameters such as pressure patch density, mesh density, weight of the mounted component and model form. Convergence metrics include spectral densities and cumulative root-mean squared (RMS) functions for acceleration, velocity, displacement, strain and interface force. Minimum frequencies for response convergence were established as well as recommendations for modeling techniques, particularly in the early stages of a component design when accurate structural vibration requirements are needed relatively quickly. The results were compared with long-established guidelines for modeling accuracy of component-loaded panels. A theoretical basis for the Response/Pressure Transfer Function (RPTF) approach provides insight into trends observed in the response predictions and confirmed in the test data. The software developed for the RPTF method allows easy replacement of the diffuse acoustic field with other pressure fields such as a turbulent boundary layer (TBL) model suitable for vehicle ascent. Structural responses

  12. Startle disease or hyperekplexia: further delineation of the syndrome.

    PubMed

    Andermann, F; Keene, D L; Andermann, E; Quesney, L F

    1980-12-01

    Startle disease is an autosomal dominant disorder with two phenotypic expressions. In the major form, there is hypertonia in infancy, and later an insecure gait. The patients have falling attacks without unconsciousness and in these, they are often injured or suffer concussions. Episodes of shaking of the limbs lasting for several minutes and resembling generalized clonus or repetitive myoclonus occur. These are most often nocturnal and are also unaccompanied by loss of consciousness. the patients are hyperreflexic and show an increased incidence of associated neurological and electroencephalographic abnormalities. The minor form of startle disease is only manifested by excessive startle and this is inconstant. In infancy it is brought out by febrile illness and in adult life by emotional stress. Gastaut and Villeneuve postulated the existence of a sporadic form of hyperekplexia different from the disorder described by Suhren et al. Review of their report and comparison with the cases of Suhren et al, and our own patients leads us to believe that the sporadic and familial forms of startle disease are the same. The disorder is rare, probably misdiagnosed initially as spastic quadriplegia, and later as epilepsy. Clonazepam appears to be the treatment of choice and its effect is sustained.

  13. The startle response and toxicology: Methods, use and interpretation.

    EPA Science Inventory

    The startle response (SR) is a sensory-evoked motor reflex that has been used successfully in toxicology for decades. Advantages of this procedure include: rapidly objective measurement of a defined neural circuit, measurement of habituation of the response, and a high potential ...

  14. Eye Blink Startle Responses in Behaviorally Inhibited and Uninhibited Children

    ERIC Educational Resources Information Center

    van Brakel, Anna M. L.; Muris, Peter; Derks, Wendy

    2006-01-01

    The present study examined the startle reflex as a physiological marker of behavioral inhibition. Participants were 7 to 12-year-old children who had been previously identified as inhibited or uninhibited as part of an ongoing longitudinal study on the role of behavioral inhibition in the development of anxiety disorders. Analysis of their scores…

  15. Emotion-modulated startle in psychopathy: Clarifying familiar effects

    PubMed Central

    Baskin-Sommers, Arielle R.; Curtin, John J.; Newman, Joseph P.

    2012-01-01

    The behavior of psychopathic individuals is thought to reflect a core fear deficit that prevents these individuals from appreciating the consequences of their choices and actions. However, growing evidence suggests that psychopathy-related emotion deficits are moderated by attention and, thus, may not reflect a reduced capacity for emotion responding. The present study attempts to reconcile this attention perspective with one of the most cited findings in psychopathy, which reports emotion-modulated startle deficits among psychopathic individuals during picture viewing. In this study, we evaluate the potential effects of a putative attention bottleneck on the emotion processing of psychopathic offenders during picture viewing by manipulating picture familiarity and examining emotion-modulated startle and late positive potential (LPP). As predicted, psychopathic individuals displayed the classic deficit in emotion-modulated startle during novel pictures, but they showed no deficit in emotion-modulated startle during familiar pictures. Conversely, results for LPP responses revealed psychopathy-related differences during familiar pictures and no psychopathy-related differences during novel pictures. Important differences related to the two Factors of psychopathy are also discussed. Overall, the results of this study not only highlight the differential importance of perceptual load on emotion processing in psychopathy, but also raise interesting questions about the varied effects of attention on psychopathy-related emotion deficits. PMID:23356218

  16. Fear-potentiated startle to threat, and prepulse inhibition among young adult non-smokers, abstinent smokers, and non-abstinent smokers

    PubMed Central

    Grillon, Christian; Avenevoli, Shelli; Daurignac, Elsa; Merikangas, Kathleen R

    2007-01-01

    Background Evidence suggests that the transition from experimental to regular smoking is facilitated by the influence of tobacco on affective and attentional mechanisms. The objective of this study was to examine affective and attentional responses in young adult smokers using fear-potentiated startle and prepulse inhibition. Methods Participants were 56 college non smokers, non-abstinent smokers, and overnight-abstinent smokers. The fear-potentiated startle test examined phasic responses to imminent threat cues and more sustained responses to unpredictable aversive events. Prepulse inhibition investigated responses to attended and ignored prepulse stimuli. Results Abstinent and non-abstinent smokers showed increased sustained potentiation of startle to contextual cues, compared to controls. Abstinent smokers showed increased fear-potentiated startle to threat cues, compared to non-smokers. PPI did not discriminate between abstinent or non-abstinent smokers and controls. Conclusion These findings suggest that negative affectivity or anxiety is associated with smoking, particularly during withdrawal. Potentiated startle may provide a valuable tool in understanding the biologic mechanisms underlying nicotine withdrawal and inform cessation and prevention efforts. PMID:17543892

  17. The Impact of Early Neglect on Defensive and Appetitive Physiology during the Pubertal Transition; a Study of Startle and Postauricular Reflexes

    PubMed Central

    Johnson, Anna E.; Loman, Michelle M.; Lafavor, Theresa; Moua, Bao; Gunnar, Megan R.

    2016-01-01

    Objective This study tested the effect of early neglect on defensive and appetitive physiology during puberty. Method Emotion-modulated reflexes, eye-blink startle (defensive) and postauricular (appetitive), were measured in 12-to-13-year-old internationally adopted youth (from foster care or from institutional settings) and compared to non-adopted US born controls. Results Startle Reflex: adopted youth displayed lower overall startle amplitude across all valences and startle potentiation to negative images was negatively related to severity of pre-adoption neglect. Postauricular reflex (PAR): adopted youth showed larger PAR magnitude across all valences. Puberty: adopted youth showed diminished PAR potentiation to positive images and startle potentiation during mid/late puberty versus the opposite pattern in not-adopted. Conclusions Early neglect was associated with blunted fast defensive reflexes and heightened fast appetitive reflexes. After puberty, early neglected youth showed physiological hyporeactivity to threatening and appetitive stimuli versus heightened reactivity in not adopted youth. Behavioral correlates in this sample and possible neurodevelopmental mechanisms of psychophysiological differences are discussed. PMID:25773732

  18. Cosmic distance-duality relation test using type Ia supernovae and the baryon acoustic oscillation

    NASA Astrophysics Data System (ADS)

    Wu, Puxun; Li, Zhengxiang; Liu, Xiaoliang; Yu, Hongwei

    2015-07-01

    A check of the validity of the distance-duality relation (DDR) is necessary since a violation of one of the assumptions underlying this relation might be possible. In this paper, we test the DDR by combining the Union2.1 type Ia supernovae (SNIa) and five angular diameter distance data from the baryonic acoustic oscillation (BAO) measurements. We find that the DDR is consistent with the observations at the 2 σ confidence level (CL) for the case of the Hubble constant h =0.7 , and the consistency is improved to be 1 σ CL when h =0.7 is replaced by the latest constraint from the Planck satellite, i.e., h =0.678 , or h is marginalized. Our results show that the BAO measurement is a very powerful tool to test the DDR. With more and more BAO data being released in the future, we are expecting a better validity check of the DDR.

  19. Methods of testing for endurance of structural elements using simulated acoustic loading

    NASA Astrophysics Data System (ADS)

    1993-10-01

    ESDU 93027 discusses methods of testing structural elements, designed to represent features of the full-size structure, using random-amplitude narrowband loading to simulate response to acoustic loading. A wide range of element geometries is included with information on probable failure locations, typical sizes, and any inherent limitations. Mounting methods are considered with examples of multiple specimen tests to allow the scatter in fatigue life to be determined in minimum elapsed time. Guidance is provided on excitation requirements, the measurement and monitoring instrumentation, specimen tuning, and the assessment of structural damping and response linearity. The means of defining a failure are considered, with particular reference to composite structures, and the use of residual strength assessment is discussed. The application of the techniques to obtain endurance data at elevated temperature is addressed. Finally, guidance is included on the interpretation of the results.

  20. Characterization of the Scale Model Acoustic Test Overpressure Environment using Computational Fluid Dynamics

    NASA Technical Reports Server (NTRS)

    Nielsen, Tanner; West, Jeff

    2015-01-01

    The Scale Model Acoustic Test (SMAT) is a 5% scale test of the Space Launch System (SLS), which is currently being designed at Marshall Space Flight Center (MSFC). The purpose of this test is to characterize and understand a variety of acoustic phenomena that occur during the early portions of lift off, one being the overpressure environment that develops shortly after booster ignition. The pressure waves that propagate from the mobile launcher (ML) exhaust hole are defined as the ignition overpressure (IOP), while the portion of the pressure waves that exit the duct or trench are the duct overpressure (DOP). Distinguishing the IOP and DOP in scale model test data has been difficult in past experiences and in early SMAT results, due to the effects of scaling the geometry. The speed of sound of the air and combustion gas constituents is not scaled, and therefore the SMAT pressure waves propagate at approximately the same speed as occurs in full scale. However, the SMAT geometry is twenty times smaller, allowing the pressure waves to move down the exhaust hole, through the trench and duct, and impact the vehicle model much faster than occurs at full scale. The DOP waves impact portions of the vehicle at the same time as the IOP waves, making it difficult to distinguish the different waves and fully understand the data. To better understand the SMAT data, a computational fluid dynamics (CFD) analysis was performed with a fictitious geometry that isolates the IOP and DOP. The upper and lower portions of the domain were segregated to accomplish the isolation in such a way that the flow physics were not significantly altered. The Loci/CHEM CFD software program was used to perform this analysis.

  1. Improved tests for global warming trend extraction in ocean acoustic travel-time data. Final technical report

    SciTech Connect

    Bottone, S.; Gray, H.L.; Woodward, W.A.

    1996-04-01

    A possible indication of the existence of global climate warming is the presence of a trend in the travel time of an acoustic signal along several ocean paths over a period of many years. This report describes new, improved tests for testing for linear trend in time series data with correlated residuals. We introduce a bootstrap based procedure to test for trend in this setting which is better adapted to controlling the significance levels. The procedure is applied to acoustic travel time data generated by the MASIG ocean model. It is shown how to generalize the improved method to multivariate, or vector, time series, which, in the ocean acoustics setting, corresponds to travel time data on many ocean paths. An appendix describes the TRENDS software, which enables the user to perform these calculations using a graphical user interface (GUI).

  2. Implementing and testing a panel-based method for modeling acoustic scattering from CFD input

    NASA Astrophysics Data System (ADS)

    Swift, S. Hales

    Exposure of sailors to high levels of noise in the aircraft carrier deck environment is a problem that has serious human and economic consequences. A variety of approaches to quieting exhausting jets from high-performance aircraft are undergoing development. However, testing of noise abatement solutions at full-scale may be prohibitively costly when many possible nozzle treatments are under consideration. A relatively efficient and accurate means of predicting the noise levels resulting from engine-quieting technologies at personnel locations is needed. This is complicated by the need to model both the direct and the scattered sound field in order to determine the resultant spectrum and levels. While the direct sound field may be obtained using CFD plus surface integral methods such as the Ffowcs-Williams Hawkings method, the scattered sound field is complicated by its dependence on the geometry of the scattering surface--the aircraft carrier deck, aircraft control surfaces and other nearby structures. In this work, a time-domain boundary element method, or TD-BEM, (sometimes referred to in terms of source panels) is proposed and developed that takes advantage of and offers beneficial effects for the substantial planar components of the aircraft carrier deck environment and uses pressure gradients as its input. This method is applied to and compared with analytical results for planar surfaces, corners and spherical surfaces using an analytic point source as input. The method can also accept input from CFD data on an acoustic data surface by using the G1A pressure gradient formulation to obtain pressure gradients on the surface from the flow variables contained on the acoustic data surface. The method is also applied to a planar scattering surface characteristic of an aircraft carrier flight deck with an acoustic data surface from a supersonic jet large eddy simulation, or LES, as input to the scattering model. In this way, the process for modeling the complete

  3. Startle responses in Parkinson patients during human gait.

    PubMed

    Nieuwenhuijzen, P H J A; Horstink, M W; Bloem, B R; Duysens, J

    2006-05-01

    Falls frequently occur in patients with Parkinson's disease (Bloem et al. 2001). One potential source for such falls during walking might be caused by the reaction to loud noises. In normal subjects startle reactions are well integrated in the locomotor activity (Nieuwenhuijzen et al. 2000), but whether this is also achieved in Parkinson patients is unknown. Therefore, in the present study, the startle response during walking was studied in eight patients with Parkinson's disease and in eight healthy subjects. To examine how startle reactions are incorporated in an ongoing gait pattern of these patients, unexpected auditory stimuli were presented in six phases of the step cycle during walking on a treadmill. For both legs electromyographic activity was recorded from biceps femoris and tibialis anterior. In addition, we measured the stance and swing phases of both legs, along with the knee angles of both legs and the left ankle angle. In all subjects and all muscles, responses were detected. The pattern of the responses, latency, duration, and phase-dependent modulation was similar in both groups. However, the mean response amplitude was larger in patients due to a smaller habituation rate. No correlation was found between the degree of habituation and disease severity. Moreover, a decreased habituation was already observed in mildly affected patients, indicating that habituation of the startle response is a sensitive measure of Parkinson's disease. The results complement the earlier findings of reduced habituation of blink responses in Parkinson's disease. With respect to behavioral changes in healthy subjects we observed that startle stimuli induced a shortening of the step cycle and a decrease in range of motion. In the patient group, less shortening of the subsequent step cycle and no decrease in range of motion of the knee and ankle was seen. It is argued that the observed changes might contribute to the high incidence of falls in patients with Parkinson

  4. Performance Optimization of a Rotor Alone Nacelle for Acoustic Fan Testing

    NASA Technical Reports Server (NTRS)

    Cunningham, C. C.; Thompson, W. K.; Hughes, C. E.

    2000-01-01

    This paper describes the techniques, equipment, and results from the optimization of a two-axis traverse actuation system used to maintain concentricity between a sting-mounted fan and a wall-mounted nacelle in the 9 x 15 (9 Foot by 15 Foot Test Section) Low Speed Wind Tunnel (LSWT) at the NASA Glenn Research Center (GRC). The Rotor Alone Nacelle (RAN) system, developed at GRC by the Engineering Design and Analysis Division (EDAD) and the Acoustics Branch, used nacelle-mounted lasers and an automated control system to maintain concentricity as thermal and thrust operating loads displace the fan relative to the nacelle. This effort was critical to ensuring rig/facility safety and experimental consistency of the acoustic data from a statorless, externally supported nacelle configuration. Although the tip clearances were originally predicted to be about 0.020 in. at maximum rotor (fan) operating speed, proximity probe measurements showed that the nominal clearance was less than 0.004 in. As a result, the system was optimized through control-loop modifications, active laser cooling, data filtering and averaging, and the development of strict operational procedures. The resultant concentricity error of RAN was reduced to +/- 0.0031 in. in the Y-direction (horizontal) and +0.0035 in./-0.001 3 in. in the Z-direction (vertical), as determined by error analysis and experimental results. Based on the success of this project, the RAN system will be transitioned to other wind tunnel research programs at NASA GRC.

  5. Monitoring accelerated carbonation on standard Portland cement mortar by nonlinear resonance acoustic test

    NASA Astrophysics Data System (ADS)

    Eiras, J. N.; Kundu, T.; Popovics, J. S.; Monzó, J.; Borrachero, M. V.; Payá, J.

    2015-03-01

    Carbonation is an important deleterious process for concrete structures. Carbonation begins when carbon dioxide (CO2) present in the atmosphere reacts with portlandite producing calcium carbonate (CaCO3). In severe carbonation conditions, C-S-H gel is decomposed into silica gel (SiO2.nH2O) and CaCO3. As a result, concrete pore water pH decreases (usually below 10) and eventually steel reinforcing bars become unprotected from corrosion agents. Usually, the carbonation of the cementing matrix reduces the porosity, because CaCO3 crystals (calcite and vaterite) occupy more volume than portlandite. In this study, an accelerated carbonation-ageing process is conducted on Portland cement mortar samples with water to cement ratio of 0.5. The evolution of the carbonation process on mortar is monitored at different levels of ageing until the mortar is almost fully carbonated. A nondestructive technique based on nonlinear acoustic resonance is used to monitor the variation of the constitutive properties upon carbonation. At selected levels of ageing, the compressive strength is obtained. From fractured surfaces the depth of carbonation is determined with phenolphthalein solution. An image analysis of the fractured surfaces is used to quantify the depth of carbonation. The results from resonant acoustic tests revealed a progressive increase of stiffness and a decrease of material nonlinearity.

  6. A finite element model to predict the sound attenuation of earplugs in an acoustical test fixture.

    PubMed

    Viallet, Guilhem; Sgard, Franck; Laville, Frédéric; Boutin, Jérôme

    2014-09-01

    Acoustical test fixtures (ATFs) are currently used to measure the attenuation of the earplugs. Several authors pointed out that the presence of an artificial skin layer inside the cylindrical ear canal of the ATFs strongly influenced the attenuation measurements. In this paper, this role is investigated via a 2D axisymmetric finite element model of a silicon earplug coupled to an artificial skin. The model is solved using COMSOL Multiphysics (COMSOL(®), Sweden) and validated experimentally. The model is exploited thereafter to better understand the role of each part of the earplug/ear canal system and how the energy circulates within the domains. This is investigated by calculating power balances and by representing the mechanical and acoustical fluxes in the system. The important dissipative role of the artificial skin is underlined and its contribution as a sound transmission pathway is quantified. In addition, the influence of both the earplug and the artificial skin parameters is assessed via sensitivities analyses performed on the model.

  7. Design considerations for the acoustic emission testing of large composite specimens

    NASA Astrophysics Data System (ADS)

    Scholey, Jonathan J.; Wilcox, Paul D.; Wisnom, Michael R.; Friswell, Mike I.

    2009-03-01

    Acoustic emission (AE) testing is a sensitive technique capable of detecting many types of defect with a sparse sensor array making it an attractive structural health monitoring technology. The widespread application of the technology is limited by a lack of predictive modelling and in part, the lack of quantitative source characteristics. The vast majority of current laboratory AE testing is conducted on small coupons which cannot be used to generate quantitative source characteristics since reflected wave energy from the specimen edges influences the received waveforms. An alternative approach is to test on large specimens where the modal properties of propagating waves can be examined with no influence from reflected wave energy. However, the design and testing of large specimens is not trivial. The work in this paper discusses the design of large fibre reinforced composite (FRC) specimens which are suitable for making quantitative source measurements. The design considerations include the minimum plate dimensions and placement of sensors. A novel technique, referred to as the location-time plot technique, is described which links propagation characteristics, specimen dimensions and sensor locations to map the dispersion of elastic waves in plates. The technique is demonstrated in the design of a simple AE experiment on a highly anisotropic plate. The technique is then used in the design of a practical AE testing arrangement for monitoring delamination from artificial defects in a large FRC plate. Experimental waveforms, recorded using this AE testing arrangement, are presented and are shown to be in agreement with the location-time plot technique.

  8. Performance, Thermal, and Vibration Qualification Testing of Zetec Acoustic Transducers, Model Z0002659-2, Sondicator Probes

    SciTech Connect

    Jacobson, G; Gemberling, S; Lavietes, A

    2006-03-10

    This report is a result of Qualification Test Plan No.001 prepared by Anthony Lavietes. The Qualification Test Plan outlines a list of requirements for thermal and vibrational testing of Zetac's Z0002659-2 Sondicator Probe acoustic transducers (hereafter called ''transducers''). The Zetec transducers are used in a system that employs an array of 7 acoustic transducers. Qualification testing of these transducers was required since they are a modified version of a standard catalog item from the manufacturer. This report documents the thermal, vibrational, and performance testing that was performed on a sampling of these transducers in order to qualify them for flight. A total of 14 transducers were tested. All 14 passed qualification testing with no failures.

  9. Evaluation of shrinkage and cracking in concrete of ring test by acoustic emission method

    NASA Astrophysics Data System (ADS)

    Watanabe, Takeshi; Hashimoto, Chikanori

    2015-03-01

    Drying shrinkage of concrete is one of the typical problems related to reduce durability and defilation of concrete structures. Lime stone, expansive additive and low-heat Portland cement are used to reduce drying shrinkage in Japan. Drying shrinkage is commonly evaluated by methods of measurement for length change of mortar and concrete. In these methods, there is detected strain due to drying shrinkage of free body, although visible cracking does not occur. In this study, the ring test was employed to detect strain and age cracking of concrete. The acoustic emission (AE) method was adopted to detect micro cracking due to shrinkage. It was recognized that in concrete using lime stone, expansive additive and low-heat Portland cement are effective to decrease drying shrinkage and visible cracking. Micro cracking due to shrinkage of this concrete was detected and evaluated by the AE method.

  10. Evaluation of Acoustic Emission NDE of Composite Crew Module Service Module/Alternate Launch Abort System (CCM SM/ALAS) Test Article Failure Tests

    NASA Technical Reports Server (NTRS)

    Horne, Michael R.; Madaras, Eric I.

    2010-01-01

    Failure tests of CCM SM/ALAS (Composite Crew Module Service Module / Alternate Launch Abort System) composite panels were conducted during July 10, 2008 and July 24, 2008 at Langley Research Center. This is a report of the analysis of the Acoustic Emission (AE) data collected during those tests.

  11. Test-bench system for a borehole azimuthal acoustic reflection imaging logging tool

    NASA Astrophysics Data System (ADS)

    Liu, Xianping; Ju, Xiaodong; Qiao, Wenxiao; Lu, Junqiang; Men, Baiyong; Liu, Dong

    2016-06-01

    The borehole azimuthal acoustic reflection imaging logging tool (BAAR) is a new generation of imaging logging tool, which is able to investigate stratums in a relatively larger range of space around the borehole. The BAAR is designed based on the idea of modularization with a very complex structure, so it has become urgent for us to develop a dedicated test-bench system to debug each module of the BAAR. With the help of a test-bench system introduced in this paper, test and calibration of BAAR can be easily achieved. The test-bench system is designed based on the client/server model. The hardware system mainly consists of a host computer, an embedded controlling board, a bus interface board, a data acquisition board and a telemetry communication board. The host computer serves as the human machine interface and processes the uploaded data. The software running on the host computer is designed based on VC++. The embedded controlling board uses Advanced Reduced Instruction Set Machines 7 (ARM7) as the micro controller and communicates with the host computer via Ethernet. The software for the embedded controlling board is developed based on the operating system uClinux. The bus interface board, data acquisition board and telemetry communication board are designed based on a field programmable gate array (FPGA) and provide test interfaces for the logging tool. To examine the feasibility of the test-bench system, it was set up to perform a test on BAAR. By analyzing the test results, an unqualified channel of the electronic receiving cabin was discovered. It is suggested that the test-bench system can be used to quickly determine the working condition of sub modules of BAAR and it is of great significance in improving production efficiency and accelerating industrial production of the logging tool.

  12. Resolution of Forces and Strain Measurements from an Acoustic Ground Test

    NASA Technical Reports Server (NTRS)

    Smith, Andrew M.; LaVerde, Bruce T.; Hunt, Ronald; Waldon, James M.

    2013-01-01

    The Conservatism in Typical Vibration Tests was Demonstrated: Vibration test at component level produced conservative force reactions by approximately a factor of 4 (approx.12 dB) as compared to the integrated acoustic test in 2 out of 3 axes. Reaction Forces Estimated at the Base of Equipment Using a Finite Element Based Method were Validated: FEM based estimate of interface forces may be adequate to guide development of vibration test criteria with less conservatism. Element Forces Estimated in Secondary Structure Struts were Validated: Finite element approach provided best estimate of axial strut forces in frequency range below 200 Hz where a rigid lumped mass assumption for the entire electronics box was valid. Models with enough fidelity to represent diminishing apparent mass of equipment are better suited for estimating force reactions across the frequency range. Forward Work: Demonstrate the reduction in conservatism provided by; Current force limited approach and an FEM guided approach. Validate proposed CMS approach to estimate coupled response from uncoupled system characteristics for vibroacoustics.

  13. The Alcock Paczy'nski test with Baryon Acoustic Oscillations: systematic effects for future surveys

    NASA Astrophysics Data System (ADS)

    Lepori, Francesca; Di Dio, Enea; Viel, Matteo; Baccigalupi, Carlo; Durrer, Ruth

    2017-02-01

    We investigate the Alcock Paczy'nski (AP) test applied to the Baryon Acoustic Oscillation (BAO) feature in the galaxy correlation function. By using a general formalism that includes relativistic effects, we quantify the importance of the linear redshift space distortions and gravitational lensing corrections to the galaxy number density fluctuation. We show that redshift space distortions significantly affect the shape of the correlation function, both in radial and transverse directions, causing different values of galaxy bias to induce offsets up to 1% in the AP test. On the other hand, we find that the lensing correction around the BAO scale modifies the amplitude but not the shape of the correlation function and therefore does not introduce any systematic effect. Furthermore, we investigate in details how the AP test is sensitive to redshift binning: a window function in transverse direction suppresses correlations and shifts the peak position toward smaller angular scales. We determine the correction that should be applied in order to account for this effect, when performing the test with data from three future planned galaxy redshift surveys: Euclid, the Dark Energy Spectroscopic Instrument (DESI) and the Square Kilometer Array (SKA).

  14. A research program to reduce interior noise in general aviation airplanes. Design of an acoustic panel test facility

    NASA Technical Reports Server (NTRS)

    Roskam, J.; Muirhead, V. U.; Smith, H. W.; Henderson, T. D.

    1977-01-01

    The design, construction, and costs of a test facility for determining the sound transmission loss characteristics of various panels and panel treatments are described. The pressurization system and electronic equipment used in experimental testing are discussed as well as the reliability of the facility and the data gathered. Tests results are compared to pertinent acoustical theories for panel behavior and minor anomalies in the data are examined. A method for predicting panel behavior in the stiffness region is also presented.

  15. Can you hear me now? Range-testing a submerged passive acoustic receiver array in a Caribbean coral reef habitat

    USGS Publications Warehouse

    Selby, Thomas H.; Hart, Kristen M.; Fujisaki, Ikuko; Smith, Brian J.; Pollock, Clayton J; Hillis-Star, Zandy M; Lundgren, Ian; Oli, Madan K.

    2016-01-01

    Submerged passive acoustic technology allows researchers to investigate spatial and temporal movement patterns of many marine and freshwater species. The technology uses receivers to detect and record acoustic transmissions emitted from tags attached to an individual. Acoustic signal strength naturally attenuates over distance, but numerous environmental variables also affect the probability a tag is detected. Knowledge of receiver range is crucial for designing acoustic arrays and analyzing telemetry data. Here, we present a method for testing a relatively large-scale receiver array in a dynamic Caribbean coastal environment intended for long-term monitoring of multiple species. The U.S. Geological Survey and several academic institutions in collaboration with resource management at Buck Island Reef National Monument (BIRNM), off the coast of St. Croix, recently deployed a 52 passive acoustic receiver array. We targeted 19 array-representative receivers for range-testing by submersing fixed delay interval range-testing tags at various distance intervals in each cardinal direction from a receiver for a minimum of an hour. Using a generalized linear mixed model (GLMM), we estimated the probability of detection across the array and assessed the effect of water depth, habitat, wind, temperature, and time of day on the probability of detection. The predicted probability of detection across the entire array at 100 m distance from a receiver was 58.2% (95% CI: 44.0–73.0%) and dropped to 26.0% (95% CI: 11.4–39.3%) 200 m from a receiver indicating a somewhat constrained effective detection range. Detection probability varied across habitat classes with the greatest effective detection range occurring in homogenous sand substrate and the smallest in high rugosity reef. Predicted probability of detection across BIRNM highlights potential gaps in coverage using the current array as well as limitations of passive acoustic technology within a complex coral reef

  16. Evaluation of the Acoustic Measurement Capability of the NASA Langley V/STOL Wind Tunnel Open Test Section with Acoustically Absorbent Ceiling and Floor Treatments

    NASA Technical Reports Server (NTRS)

    Theobald, M. A.

    1978-01-01

    The single source location used for helicopter model studies was utilized in a study to determine the distances and directions upstream of the model accurate at which measurements of the direct acoustic field could be obtained. The method used was to measure the decrease of sound pressure levels with distance from a noise source and thereby determine the Hall radius as a function of frequency and direction. Test arrangements and procedures are described. Graphs show the normalized sound pressure level versus distance curves for the glass fiber floor treatment and for the foam floor treatment.

  17. Preliminary vibration, acoustic, and shock design and test criteria for components on the Lightweight External Tank (LWT)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The Space Shuttle LWT is divided into zones and subzones. Zones are designated primarily to assist in determining the applicable specifications. A subzone (general Specification) is available for use when the location of the component is known but component design and weight are not well defined. When the location, weight, and mounting configuration of the component are known, specifications for appropriate subzone weight ranges are available. Along with the specifications are vibration, acoustic, shock, transportation, handling, and acceptance test requirements and procedures. A method of selecting applicable vibration, acoustic, and shock specifications is presented.

  18. Acoustic communication in territorial butterflyfish: test of the sound production hypothesis.

    PubMed

    Tricas, Timothy C; Kajiura, Stephen M; Kosaki, Randall K

    2006-12-01

    Butterflyfishes are conspicuous members of coral reefs and well known for their visual displays during social interactions. Members of the genus Chaetodon have a unique peripheral arrangement of the anterior swim bladder that connects with the lateral line (the laterophysic connection) and in many species projects towards the inner ear. This morphology has lead to the proposal that the laterophysic connection and swim bladder system may be a specialized structure for the detection of sound. However, the relevant stimuli, receiver mechanisms and functions for these putative hearing structures were unknown because butterflyfishes were previously not recognized to produce sounds during natural behavior. We performed field experiments to test the hypothesis that Chaetodon produces sounds in natural social contexts. Acoustic and motor behaviors of the monogamous multiband butterflyfish, C. multicinctus, were evoked and recorded by placement of bottled fish into feeding territories of conspecific pairs. We demonstrate that territory defense includes the production of agonistic sounds and hydrodynamic stimuli that are associated with tail slap, jump, pelvic fin flick and dorsal-anal fin erection behaviors. In addition, grunt pulse trains were produced by bottled intruders and are tentatively interpreted to function as an alert call among pair mates. Acoustic behaviors include low frequency hydrodynamic pulses <100 Hz, sounds with peak energy from 100 Hz to 500 Hz, and a broadband high frequency click (peak frequency=3.6 kHz), which is produced only during the tail slap behavior. These results provide a biological framework for future studies to interpret the proximate function of the acoustico-lateralis sensory system, the evolution of the laterophysic mechanism and their relevance to butterflyfish social behavior.

  19. Gender differences in children's singing voices: acoustic analyses and results of a listening test.

    PubMed

    Mecke, Ann-Christine; Sundberg, Johan

    2010-05-01

    This study tested the hypothesis that acoustic parameters exist which are specific to gender in children's singing voices, and that these parameters are relevant to listeners' identification of gender of children's singing voices. A listening test was run with examples of singing produced by children belonging to different singing cultures, six boys and six girls from a Swedish music school and six boys from an elite German boys' choir. Sustained vowels were analyzed with regard to formants and voice source properties (jitter, shimmer and glottal-to-noise-excitation rate, closed quotient, and normalized amplitude quotient). Most of the measured parameters differed significantly between the boys belonging to the two different singing cultures. Regarding boys and girls from the same choir, only the closed quotient and the fourth formant frequency differed significantly. The listening test was carried out by an expert panel. The listeners correctly identified the gender of the singer in 66.0% of the cases, i.e., far better than chance. A multiple linear regression analysis revealed that the listener's answers correlated well with the formant frequencies, with the fourth formant showing the highest correlation.

  20. Acoustic test and analysis of a counterrotating prop-fan model

    NASA Technical Reports Server (NTRS)

    Magliozzi, Bernard; Brown, Paul; Parzych, David

    1987-01-01

    Results of acoustic tests of a 62.2 cm (24.5 in) diameter model counterrotating Prop-Fan are presented. The model was tested as a tractor and a pusher downstream of a pylon, both at 0 degrees and at 4 degrees angle-of-attack. The effects on noise of spacing between rotors and between the pylons and the rotors were also measured. Effects of rotor spacing were found to cause small changes in noise over the range of spacings tested. The presence of the pylon resulted in a 2 to 3 EPNdB increase in noise. Angle-of-attack effects showed an increase of 3 to 4 EPNdB for the tractor and only about 1 EPNdB for the pusher configuration. Speed was found to be the strongest parameter in minimizing noise. However, the decrease in noise with tip speeds below 200 m/sec (650 ft/sec) became significantly smaller than at higher tip speeds. Comparison of noise spectra between single rotation and counterrotating Prop-Fans showed that the counterrotating Prop-Fan has significantly higher levels of higher frequency noise which radiates in the forward direction. Correlations between measurement and prediction are discussed. Predictions are made of far-field noise during takeoff and near-field noise during cruise.

  1. Field testing of a convergent array of acoustic Doppler profilers for high-resolution velocimetry in energetic tidal currents

    SciTech Connect

    Harding, Samuel F.; Sellar, Brian; Richmond, Marshall C.

    2016-04-25

    An array of single-beam acoustic Doppler profilers has been developed for the high resolution measurement of three-dimensional tidal flow velocities and subsequently tested in an energetic tidal site. This configuration has been developed to increase spatial resolution of velocity measurements in comparison to conventional acoustic Doppler profilers (ADPs) which characteristically use divergent acoustic beams emanating from a single instrument. This is achieved using geometrically convergent acoustic beams creating a sample volume at the focal point of 0.03 m3. Away from the focal point, the array is also able to simultaneously reconstruct three-dimensional velocity components in a profile throughout the water column, and is referred to herein as a convergent-beam acoustic Doppler profiler (C-ADP). Mid-depth profiling is achieved through integration of the sensor platform with the operational commercial-scale Alstom 1MW DeepGen-IV Tidal Turbine deployed at the European Marine Energy Center, Orkney Isles, UK. This proof-of-concept paper outlines the C-ADP system configuration and comparison to measurements provided by co-installed reference instrumentation.

  2. Testing of containers made of glass-fiber reinforced plastic with the aid of acoustic emission analysis

    NASA Technical Reports Server (NTRS)

    Wolitz, K.; Brockmann, W.; Fischer, T.

    1979-01-01

    Acoustic emission analysis as a quasi-nondestructive test method makes it possible to differentiate clearly, in judging the total behavior of fiber-reinforced plastic composites, between critical failure modes (in the case of unidirectional composites fiber fractures) and non-critical failure modes (delamination processes or matrix fractures). A particular advantage is that, for varying pressure demands on the composites, the emitted acoustic pulses can be analyzed with regard to their amplitude distribution. In addition, definite indications as to how the damages occurred can be obtained from the time curves of the emitted acoustic pulses as well as from the particular frequency spectrum. Distinct analogies can be drawn between the various analytical methods with respect to whether the failure modes can be classified as critical or non-critical.

  3. Acoustic Nondestructive Testing and Measurement of Tension for Steel Reinforcing Members: Part 2 - Field Testing

    DTIC Science & Technology

    2014-09-01

    BACKGROUND: Many reinforced concrete structures contain embedded pre- and post- tensioned steel members that are subject to corrosion and fracturing...Tension for Steel Reinforcing Members Part 2 – Field Testing by Michael K. McInerney PURPOSE: This Coastal and Hydraulics Engineering Technical...Specifically, the technology application addresses the problem of determining tension in concrete -embedded pre- and post-tensioned reinforcement rods

  4. Startle auditory stimuli enhance the performance of fast dynamic contractions.

    PubMed

    Fernandez-Del-Olmo, Miguel; Río-Rodríguez, Dan; Iglesias-Soler, Eliseo; Acero, Rafael M

    2014-01-01

    Fast reaction times and the ability to develop a high rate of force development (RFD) are crucial for sports performance. However, little is known regarding the relationship between these parameters. The aim of this study was to investigate the effects of auditory stimuli of different intensities on the performance of a concentric bench-press exercise. Concentric bench-presses were performed by thirteen trained subjects in response to three different conditions: a visual stimulus (VS); a visual stimulus accompanied by a non-startle auditory stimulus (AS); and a visual stimulus accompanied by a startle auditory stimulus (SS). Peak RFD, peak velocity, onset movement, movement duration and electromyography from pectoralis and tricep muscles were recorded. The SS condition induced an increase in the RFD and peak velocity and a reduction in the movement onset and duration, in comparison with the VS and AS condition. The onset activation of the pectoralis and tricep muscles was shorter for the SS than for the VS and AS conditions. These findings point out to specific enhancement effects of loud auditory stimulation on the rate of force development. This is of relevance since startle stimuli could be used to explore neural adaptations to resistance training.

  5. Startle Auditory Stimuli Enhance the Performance of Fast Dynamic Contractions

    PubMed Central

    Fernandez-Del-Olmo, Miguel; Río-Rodríguez, Dan; Iglesias-Soler, Eliseo; Acero, Rafael M.

    2014-01-01

    Fast reaction times and the ability to develop a high rate of force development (RFD) are crucial for sports performance. However, little is known regarding the relationship between these parameters. The aim of this study was to investigate the effects of auditory stimuli of different intensities on the performance of a concentric bench-press exercise. Concentric bench-presses were performed by thirteen trained subjects in response to three different conditions: a visual stimulus (VS); a visual stimulus accompanied by a non-startle auditory stimulus (AS); and a visual stimulus accompanied by a startle auditory stimulus (SS). Peak RFD, peak velocity, onset movement, movement duration and electromyography from pectoralis and tricep muscles were recorded. The SS condition induced an increase in the RFD and peak velocity and a reduction in the movement onset and duration, in comparison with the VS and AS condition. The onset activation of the pectoralis and tricep muscles was shorter for the SS than for the VS and AS conditions. These findings point out to specific enhancement effects of loud auditory stimulation on the rate of force development. This is of relevance since startle stimuli could be used to explore neural adaptations to resistance training. PMID:24489967

  6. Corpus callosotomy in a patient with startle epilepsy.

    PubMed

    Gómez, Nicolás Garófalo; Hamad, Ana Paula; Marinho, Murilo; Tavares, Igor M; Carrete, Henrique; Caboclo, Luís Otávio; Yacubian, Elza Márcia; Centeno, Ricardo

    2013-03-01

    Startle epilepsy is a syndrome of reflex epilepsy in which the seizures are precipitated by a sudden and surprising, usually auditory, stimulus. We describe herein a girl who had been suffering with startle-induced seizures since 2 years of age. She had focal, tonic and tonic-clonic seizures, refractory to antiepileptic treatment. Daily tonic seizures led to very frequent falls and morbidity. Neurologically, she had no deficit. Interictal EEG showed slow waves and epileptiform discharges in central and fronto-central regions. Video-polygraphic recordings of seizures, triggered by stimuli, showed generalised symmetric tonic posturing with ictal EEG, characterised by an abrupt and diffuse electrodecremental pattern of fast activity, followed by alpha-theta rhythm superimposed by epileptic discharges predominantly over the vertex and anterior regions. Magnetic resonance imaging showed no abnormalities. Corpus callosotomy was performed when the patient was 17. Since surgery, the patient (one year follow-up) has remained seizure-free. Corpus callosotomy may be considered in patients with startle epilepsy and tonic seizures, in the absence of focal lesions amenable to surgery. [Published with video sequences].

  7. Aero-acoustic tests of duct-burning turbofan exhaust nozzles

    NASA Technical Reports Server (NTRS)

    Kozlowski, H.; Packman, A. B.

    1976-01-01

    The acoustic and aerodynamic characteristics of several exhaust systems suitable for duct burning turbofan engines are evaluated. Scale models representing unsuppressed coannular exhaust systems are examined statically under varying exhaust conditions. Ejectors with both hardwall and acoustically treated inserts are investigated.

  8. Teaching Acoustic Properties of Materials in Secondary School: Testing Sound Insulators

    ERIC Educational Resources Information Center

    Hernandez, M. I.; Couso, D.; Pinto, R.

    2011-01-01

    Teaching the acoustic properties of materials is a good way to teach physics concepts, extending them into the technological arena related to materials science. This article describes an innovative approach for teaching sound and acoustics in combination with sound insulating materials in secondary school (15-16-year-old students). Concerning the…

  9. Changes in trauma-potentiated startle with treatment of posttraumatic stress disorder in combat Veterans.

    PubMed

    Robison-Andrew, E Jenna; Duval, Elizabeth R; Nelson, C Beau; Echiverri-Cohen, Aileen; Giardino, Nicholas; Defever, Andrew; Norrholm, Seth D; Jovanovic, Tanja; Rothbaum, Barbara O; Liberzon, Israel; Rauch, Sheila A M

    2014-05-01

    Emotional Processing Theory proposes that habituation to trauma-related stimuli is an essential component of PTSD treatment. However, the mechanisms underlying treatment-related habituation are not well understood. We examined one psychophysiological measure that holds potential for elucidating the biological processes involved in treatment response: trauma-potentiated startle response. Seventeen OEF/OIF combat Veterans participated in the study and completed three assessments using a trauma-potentiated startle paradigm over PTSD treatment. Results revealed different patterns of trauma-potentiated startle across treatment for responders and nonresponders, but no differences in within task habituation. Responders showed an increase followed by a decrease in trauma-potentiated startle, whereas nonresponders showed a relatively flat response profile. Results suggested that PTSD patients who engage with emotional content as demonstrated by greater startle reactivity may be more likely to respond to PTSD treatment. Furthermore, trauma-potentiated startle shows promise as an objective measure of psychophysiological responses involved in PTSD recovery.

  10. Design and Development of a Deep Acoustic Lining for the 40-by 80-Foot Wind Tunnel Test Section

    NASA Technical Reports Server (NTRS)

    Soderman, Paul T.; Schmitz, Fredric H.; Allen, Christopher S.; Jaeger, Stephen M.; Sacco, Joe N.; Mosher, Marianne; Hayes, Julie A.

    2002-01-01

    The work described in this report has made effective use of design teams to build a state-of-the-art anechoic wind-tunnel facility. Many potential design solutions were evaluated using engineering analysis, and computational tools. Design alternatives were then evaluated using specially developed testing techniques, Large-scale coupon testing was then performed to develop confidence that the preferred design would meet the acoustic, aerodynamic, and structural objectives of the project. Finally, designs were frozen and the final product was installed in the wind tunnel. The result of this technically ambitious project has been the creation of a unique acoustic wind tunnel. Its large test section (39 ft x 79 ft x SO ft), potentially near-anechoic environment, and medium subsonic speed capability (M = 0.45) will support a full range of aeroacoustic testing-from rotorcraft and other vertical takeoff and landing aircraft to the take-off/landing configurations of both subsonic and supersonic transports.

  11. Correlation of FEM/BEM Vibroacoustic Prediction to System-Level Acoustic Test Results

    NASA Astrophysics Data System (ADS)

    Rodrigues, G.; Ngan, I.; Santiago-Prowald, J.

    2014-06-01

    Coupled FEM/BEM vibroacoustic analyses are employed for deriving spacecraft random vibration environments and supporting the design of low aerial density structures. They offer deterministic predictions which are very accurate at low-frequency and meaningful across all the spectrum of interest for vibroacoustic response.An assessment of the standard procedure of FEM/BEM vibroacoustic analyses was carried out by correlation to measurements from system-level tests of several spacecraft. This allowed a quantification of the typical errors committed, and concluded on the adequacy of applying the standard factor of safety +4dB to the predictions. It was observed that a major source of error is the lack of representativeness of the models of the spacecraft, which adds to the diffuse field idealization made on the acoustic environment inside the fairing and the test chambers. In particular, it was observed a clear impact from a lack of detail of the damping of the structure, and an often crude lumped representation of units and equipment as well as tanks and fixations.

  12. Evaluating damage potential of cryogenic concrete using acoustic emission sensors and permeability testing

    NASA Astrophysics Data System (ADS)

    Kogbara, Reginald B.; Parsaei, Boback; Iyengar, Srinath R.; Grasley, Zachary C.; Masad, Eyad A.; Zollinger, Dan G.

    2014-04-01

    This study evaluates the damage potential of concrete of different mix designs subjected to cryogenic temperatures, using acoustic emission (AE) and permeability testing. The aim is to investigate design methodologies that might be employed to produce concrete that resists damage when cooled to cryogenic temperatures. Such concrete would be suitable for primary containment of liquefied natural gas (LNG) and could replace currently used 9% Ni steel, thereby leading to huge cost savings. In the experiments described, concrete cubes, 150 mm x 150 mm x 150 mm, were cast using four different mix designs. The four mixes employed siliceous river sand as fine aggregate. Moreover, limestone, sandstone, trap rock and lightweight aggregate were individually used as coarse aggregates in the mixes. The concrete samples were then cooled from room temperature (20°C) to cryogenic temperature (-165°C) in a temperature chamber. AE sensors were placed on the concrete cubes during the cryogenic freezing process. The damage potential was evaluated in terms of the growth of damage as determined from AE, as a function of temperature and concrete mixture design. The damage potential observed was validated with water permeability testing. Initial results demonstrate the effects of the coefficient of thermal expansion (CTE) of the aggregates on damage growth. Concrete damage (cracking) resistance generally decreased with increasing coarse aggregate CTE, and was in the order, limestone ≥ trap rock << lightweight aggregate ≥ sandstone. Work is in progress to fully understand thermal dilation and damage growth in concrete due to differential CTE of its components.

  13. Acoustic and aerodynamic testing of a scale model variable pitch fan

    NASA Technical Reports Server (NTRS)

    Jutras, R. R.; Kazin, S. B.

    1974-01-01

    A fully reversible pitch scale model fan with variable pitch rotor blades was tested to determine its aerodynamic and acoustic characteristics. The single-stage fan has a design tip speed of 1160 ft/sec (353.568 m/sec) at a bypass pressure ratio of 1.5. Three operating lines were investigated. Test results show that the blade pitch for minimum noise also resulted in the highest efficiency for all three operating lines at all thrust levels. The minimum perceived noise on a 200-ft (60.96 m) sideline was obtained with the nominal nozzle. At 44% of takeoff thrust, the PNL reduction between blade pitch and minimum noise blade pitch is 1.8 PNdB for the nominal nozzle and decreases with increasing thrust. The small nozzle (6% undersized) has the highest efficiency at all part thrust conditions for the minimum noise blade pitch setting; although, the noise is about 1.0 PNdB higher for the small nozzle at the minimum noise blade pitch position.

  14. Azimuthal cement evaluation with an acoustic phased-arc array transmitter: numerical simulations and field tests

    NASA Astrophysics Data System (ADS)

    Che, Xiao-Hua; Qiao, Wen-Xiao; Ju, Xiao-Dong; Wang, Rui-Jia

    2016-03-01

    We developed a novel cement evaluation logging tool, named the azimuthally acoustic bond tool (AABT), which uses a phased-arc array transmitter with azimuthal detection capability. We combined numerical simulations and field tests to verify the AABT tool. The numerical simulation results showed that the radiation direction of the subarray corresponding to the maximum amplitude of the first arrival matches the azimuth of the channeling when it is behind the casing. With larger channeling size in the circumferential direction, the amplitude difference of the casing wave at different azimuths becomes more evident. The test results showed that the AABT can accurately locate the casing collars and evaluate the cement bond quality with azimuthal resolution at the casing—cement interface, and can visualize the size, depth, and azimuth of channeling. In the case of good casing—cement bonding, the AABT can further evaluate the cement bond quality at the cement—formation interface with azimuthal resolution by using the amplitude map and the velocity of the formation wave.

  15. Genetic Control of Startle Behavior in Medaka Fish

    PubMed Central

    Tsuboko, Satomi; Kimura, Tetsuaki; Shinya, Minori; Suehiro, Yuji; Okuyama, Teruhiro; Shimada, Atsuko; Takeda, Hiroyuki; Naruse, Kiyoshi; Kubo, Takeo; Takeuchi, Hideaki

    2014-01-01

    Genetic polymorphisms are thought to generate intraspecific behavioral diversities, both within and among populations. The mechanisms underlying genetic control of behavioral properties, however, remain unclear in wild-type vertebrates, including humans. To explore this issue, we used diverse inbred strains of medaka fish (Oryzias latipes) established from the same and different local populations. Medaka exhibit a startle response to a visual stimulus (extinction of illumination) by rapidly bending their bodies (C-start) 20-ms after the stimulus presentation. We measured the rates of the response to repeated stimuli (1-s interval, 40 times) among four inbred strains, HNI-I, HNI-II, HO5, and Hd-rR-II1, and quantified two properties of the startle response: sensitivity (response rate to the first stimulus) and attenuation of the response probability with repeated stimulus presentation. Among the four strains, the greatest differences in these properties were detected between HNI-II and Hd-rR-II1. HNI-II exhibited high sensitivity (approximately 80%) and no attenuation, while Hd-rR-II1 exhibited low sensitivity (approximately 50%) and almost complete attenuation after only five stimulus presentations. Our findings suggested behavioral diversity of the startle response within a local population as well as among different populations. Linkage analysis with F2 progeny between HNI-II and Hd-rR-II1 detected quantitative trait loci (QTL) highly related to attenuation, but not to sensitivity, with a maximum logarithm of odds score of 11.82 on linkage group 16. The three genotypes (homozygous for HNI-II and Hd-rR-II1 alleles, and heterozygous) at the marker nearest the QTL correlated with attenuation. Our findings are the first to suggest that a single genomic region might be sufficient to generate individual differences in startle behavior between wild-type strains. Further identification of genetic polymorphisms that define the behavioral trait will contribute to our

  16. Vibration, acoustic, and shock design and test criteria for components on the Solid Rocket Boosters (SRB), Lightweight External Tank (LWT), and Space Shuttle Main Engines (SSME)

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The vibration, acoustics, and shock design and test criteria for components and subassemblies on the space shuttle solid rocket booster (SRB), lightweight tank (LWT), and main engines (SSME) are presented. Specifications for transportation, handling, and acceptance testing are also provided.

  17. Glycine and GABAA receptors mediate tonic and phasic inhibitory processes that contribute to prepulse inhibition in the goldfish startle network

    PubMed Central

    Curtin, Paul C. P.; Preuss, Thomas

    2015-01-01

    Prepulse inhibition (PPI) is understood as a sensorimotor gating process that attenuates sensory flow to the startle pathway during early stages (20–1000 ms) of information processing. Here, we applied in vivo electrophysiology and pharmacology to determine if PPI is mediated by glycine receptors (GlyRs) and/or GABAA receptors (GABAARs) in the goldfish auditory startle circuit. Specifically, we used selective antagonists to dissect the contributions of target receptors on sound-evoked postsynaptic potentials (PSPs) recorded in the neurons that initiate startle, the Mauthner-cells (M-cell). We found that strychnine, a GlyR antagonist, disrupted a fast-activated (5 ms) and rapidly (<50 ms) decaying (feed-forward) inhibitory process that contributes to PPI at 20 ms prepulse/pulse inter-stimulus intervals (ISI). Additionally we observed increases of the evoked postsynaptic potential (PSP) peak amplitude (+87.43 ± 21.53%, N = 9) and duration (+204 ± 48.91%, N = 9). In contrast, treatment with bicuculline, a GABAAR antagonist, caused a general reduction in PPI across all tested interstimulus intervals (ISIs) (20–500 ms). Bicuculline also increased PSP peak amplitude (+133.8 ± 10.3%, N = 5) and PSP duration (+284.95 ± 65.64%, N = 5). Treatment with either antagonist also tonically increased post-synaptic excitability in the M-cells, reflected by an increase in the magnitude of antidromically-evoked action potentials (APs) by 15.07 ± 3.21%, N = 7 and 16.23 ± 7.08%, N = 5 for strychnine and bicuculline, respectively. These results suggest that GABAARs and GlyRs are functionally segregated to short- and longer-lasting sound-evoked (phasic) inhibitory processes that contribute to PPI, with the mediation of tonic inhibition by both receptor systems being critical for gain control within the M-cell startle circuit. PMID:25852486

  18. Mutations in the human GlyT2 gene define a presynaptic component of human startle disease

    PubMed Central

    Rees, Mark I.; Harvey, Kirsten; Pearce, Brian R.; Chung, Seo-Kyung; Duguid, Ian C.; Thomas, Philip; Beatty, Sarah; Graham, Gail E.; Armstrong, Linlea; Shiang, Rita; Abbott, Kim J.; Zuberi, Sameer M.; Stephenson, John B.P.; Owen, Michael J.; Tijssen, Marina A.J.; van den Maagdenberg, Arn M.J.M.; Smart, Trevor G.; Supplisson, Stéphane; Harvey, Robert J.

    2011-01-01

    Hyperekplexia is a human neurological disorder characterized by an excessive startle response and is typically caused by missense and nonsense mutations in the gene encoding the inhibitory glycine receptor (GlyR) α1 subunit (GLRA1)1-3. Genetic heterogeneity has been confirmed in isolated sporadic cases with mutations in other postsynaptic glycinergic proteins including the GlyR β subunit (GLRB)4, gephyrin (GPHN)5 and RhoGEF collybistin (ARHGEF9)6. However, many sporadic patients diagnosed with hyperekplexia do not carry mutations in these genes2-7. Here we reveal that missense, nonsense and frameshift mutations in the presynaptic glycine transporter 2 (GlyT2) gene (SLC6A5)8 also cause hyperekplexia. Patients harbouring mutations in SLC6A5 presented with hypertonia, an exaggerated startle response to tactile or acoustic stimuli, and life-threatening neonatal apnoea episodes. GlyT2 mutations result in defective subcellular localisation and/or decreased glycine uptake, with selected mutations affecting predicted glycine and Na+ binding sites. Our results demonstrate that SLC6A5 is a major gene for hyperekplexia and define the first neurological disorder linked to mutations in a Na+/Cl−-dependent transporter for a classical fast neurotransmitter. By analogy, we suggest that in other human disorders where defects in postsynaptic receptors have been identified, similar symptoms could result from defects in the cognate presynaptic neurotransmitter transporter. PMID:16751771

  19. Startle response memory and hippocampal changes in adult zebrafish pharmacologically-induced to exhibit anxiety/depression-like behaviors.

    PubMed

    Pittman, Julian T; Lott, Chad S

    2014-01-17

    Zebrafish (Danio rerio) are rapidly becoming a popular animal model for neurobehavioral and psychopharmacological research. While startle testing is a well-established assay to investigate anxiety-like behaviors in different species, screening of the startle response and its habituation in zebrafish is a new direction of translational biomedical research. This study focuses on a novel behavioral protocol to assess a tapping-induced startle response and its habituation in adult zebrafish that have been pharmacologically-induced to exhibit anxiety/depression-like behaviors. We demonstrated that zebrafish exhibit robust learning performance in a task adapted from the mammalian literature, a modified plus maze, and showed that ethanol and fluoxetine impair memory performance in this maze when administered after training at a dose that does not impair motor function, however, leads to significant upregulation of hippocampal serotoninergic neurons. These results suggest that the maze associative learning paradigm has face and construct validity and that zebrafish may become a translationally relevant study species for the analysis of the mechanisms of learning and memory changes associated with psychopharmacological treatment of anxiety/depression.

  20. Contextual-specificity of short-delay extinction in humans: Renewal of fear-potentiated startle in a virtual environment

    PubMed Central

    Alvarez, Ruben P.; Johnson, Linda; Grillon, Christian

    2007-01-01

    A recent fear-potentiated startle study in rodents suggested that extinction was not context dependent when extinction was conducted after a short delay following acquisition, suggesting that extinction can lead to erasure of fear learning in some circumstances. The main objective of this study was to attempt to replicate these findings in humans by examining the context specificity of short-delay extinction in an ABA renewal procedure using virtual reality environments. A second objective was to examine whether renewal, if any, would be influenced by context conditioning. Subjects underwent differential aversive conditioning in virtual context A, which was immediately followed by extinction in virtual context B. Extinction was followed by tests of renewal in context A and B, with the order counterbalanced across subjects. Results showed that extinction was context dependent. Evidence for renewal was established using fear-potentiated startle as well as skin conductance and fear ratings. In addition, although contextual anxiety was greater in the acquisition context than in the extinction context during renewal, as assessed with startle, context conditioning did not influence the renewal effect. These data do not support the view that extinction conducted shortly after acquisition is context independent. Hence, they do not provide evidence that extinction can lead to erasure of a fear memory established via Pavlovian conditioning. PMID:17412963

  1. Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice

    PubMed Central

    Smith, Kiersten S.; Meloni, Edward G.; Myers, Karyn M.; Veer, Ashlee Van't; Carlezon, William A.; Rudolph, Uwe

    2011-01-01

    Rationale Anxiety disorders affect 18% of the United States adult population annually. Recent surges in the diagnosis of posttraumatic stress disorder (PTSD) from combat-exposed veterans have prompted an urgent need to understand the pathophysiology underlying this debilitating condition. Objectives Anxiety and fear responses are partly modulated by gamma aminobutyric acid type A (GABAA) receptor-mediated synaptic inhibition; benzodiazepines potentiate GABAergic inhibition and are effective anxiolytics. Many genetically modified mouse lines are generated and/or maintained on the C57BL/6J background, a strain where manipulation of anxiety-like behavior using benzodiazepines is difficult. Fear-potentiated startle (FPS), a test of conditioned fear, is a useful preclinical tool to study PTSD-like responses but has been difficult to establish in C57BL/6J mice. Methods We modified several FPS experimental parameters and developed a paradigm to assess conditioned fear in C57BL/6J mice. The 6-day protocol consisted of three startle Acclimation days, a Pre-Test day followed by Training and Testing for FPS. Subject responses to the effects of three benzodiazepines were also examined. Results C57BL/6J mice had low levels of unconditioned fear assessed during Pre-Test (15–18%) but showed robust FPS (80–120%) during the Test session. Conditioned fear responses extinguished over repeated test sessions. Administration of the benzodiazepines alprazolam (0.5 and 1 mg/kg, i.p.), chlordiazepoxide (5 and 10 mg/kg, i.p.), and diazepam (1, 2, and 4 mg/kg, i.p.) significantly reduced FPS to Pre-Test levels. Conclusions We used a modified and pharmacologically-validated paradigm to assess FPS in mice thereby providing a powerful tool to examine the neurobiology of PTSD in genetic models of anxiety generated on the C57BL/6J background. PMID:20922362

  2. Study and application of acoustic emission testing in fault diagnosis of low-speed heavy-duty gears.

    PubMed

    Gao, Lixin; Zai, Fenlou; Su, Shanbin; Wang, Huaqing; Chen, Peng; Liu, Limei

    2011-01-01

    Most present studies on the acoustic emission signals of rotating machinery are experiment-oriented, while few of them involve on-spot applications. In this study, a method of redundant second generation wavelet transform based on the principle of interpolated subdivision was developed. With this method, subdivision was not needed during the decomposition. The lengths of approximation signals and detail signals were the same as those of original ones, so the data volume was twice that of original signals; besides, the data redundancy characteristic also guaranteed the excellent analysis effect of the method. The analysis of the acoustic emission data from the faults of on-spot low-speed heavy-duty gears validated the redundant second generation wavelet transform in the processing and denoising of acoustic emission signals. Furthermore, the analysis illustrated that the acoustic emission testing could be used in the fault diagnosis of on-spot low-speed heavy-duty gears and could be a significant supplement to vibration testing diagnosis.

  3. Study and Application of Acoustic Emission Testing in Fault Diagnosis of Low-Speed Heavy-Duty Gears

    PubMed Central

    Gao, Lixin; Zai, Fenlou; Su, Shanbin; Wang, Huaqing; Chen, Peng; Liu, Limei

    2011-01-01

    Most present studies on the acoustic emission signals of rotating machinery are experiment-oriented, while few of them involve on-spot applications. In this study, a method of redundant second generation wavelet transform based on the principle of interpolated subdivision was developed. With this method, subdivision was not needed during the decomposition. The lengths of approximation signals and detail signals were the same as those of original ones, so the data volume was twice that of original signals; besides, the data redundancy characteristic also guaranteed the excellent analysis effect of the method. The analysis of the acoustic emission data from the faults of on-spot low-speed heavy-duty gears validated the redundant second generation wavelet transform in the processing and denoising of acoustic emission signals. Furthermore, the analysis illustrated that the acoustic emission testing could be used in the fault diagnosis of on-spot low-speed heavy-duty gears and could be a significant supplement to vibration testing diagnosis. PMID:22346592

  4. Presidential Address 2014: The more-or-less interrupting effects of the startle response.

    PubMed

    Blumenthal, Terry D

    2015-11-01

    The startle response can be used to assess differences in a variety of ongoing processes across species, sensory modalities, ages, clinical conditions, and task conditions. Startle serves defensive functions, but it may also interrupt ongoing processes, allowing for a reorientation of resources to potential danger. A wealth of research suggests that prepulse inhibition of startle (PPI) is an indicator of the protection of the processing of the prepulse from interruption by the startle response. However, protection against interruption by suppressing the startle response may extend to many other ongoing processes, including the higher processing of the startle stimulus itself. Proof of protection would require measuring ongoing processing, which has very rarely been reported. The idea that PPI represents the protection of the earliest stages of prepulse processing can be challenged, since those earliest stages are completed by the time the startle response occurs, so they are not threatened by interruption and need not be protected. The conception of low PPI as indicative of a "gating deficit" in schizophrenia should be made with caution, since low PPI is seen in some, but not all studies of schizophrenia, but also in a range of other disorders and conditions. Finally, startle is often used to probe ongoing processes, but the response also modifies those processes, interrupting some processes but perhaps facilitating others. A deeper understanding of the function of startle and PPI might improve the precision of application of these measures in the investigation of a range of research topics.

  5. Characterization of Pump-Induced Acoustics in Space Launch System Main Propulsion System Liquid Hydrogen Feedline Using Airflow Test Data

    NASA Technical Reports Server (NTRS)

    Eberhart, C. J.; Snellgrove, L. M.; Zoladz, T. F.

    2015-01-01

    High intensity acoustic edgetones located upstream of the RS-25 Low Pressure Fuel Turbo Pump (LPFTP) were previously observed during Space Launch System (STS) airflow testing of a model Main Propulsion System (MPS) liquid hydrogen (LH2) feedline mated to a modified LPFTP. MPS hardware has been adapted to mitigate the problematic edgetones as part of the Space Launch System (SLS) program. A follow-on airflow test campaign has subjected the adapted hardware to tests mimicking STS-era airflow conditions, and this manuscript describes acoustic environment identification and characterization born from the latest test results. Fluid dynamics responsible for driving discrete excitations were well reproduced using legacy hardware. The modified design was found insensitive to high intensity edgetone-like discretes over the bandwidth of interest to SLS MPS unsteady environments. Rather, the natural acoustics of the test article were observed to respond in a narrowband-random/mixed discrete manner to broadband noise thought generated by the flow field. The intensity of these responses were several orders of magnitude reduced from those driven by edgetones.

  6. Flight effects on the aerodynamic and acoustic characteristics of inverted profile coannular nozzles, volume 2. [supersonic cruise aircraft research wind tunnel tests

    NASA Technical Reports Server (NTRS)

    Kozlowski, H.; Packman, A. B.

    1978-01-01

    Data from the acoustic tests of the convergent reference nozzle and the 0.75 area ratio coannular nozzle are presented in tables. Data processing routines used to scale the acoustic data and to correct the data for atmospheric attenuation are included.

  7. Acoustical and Intelligibility Test of the Vocera(Copyright) B3000 Communication Badge

    NASA Technical Reports Server (NTRS)

    Archer, Ronald; Litaker, Harry; Chu, Shao-Sheng R.; Simon, Cory; Romero, Andy; Moses, Haifa

    2012-01-01

    To communicate with each other or ground support, crew members on board the International Space Station (ISS) currently use the Audio Terminal Units (ATU), which are located in each ISS module. However, to use the ATU, crew members must stop their current activity, travel to a panel, and speak into a wall-mounted microphone, or use either a handheld microphone or a Crew Communication Headset that is connected to a panel. These actions unnecessarily may increase task times, lower productivity, create cable management issues, and thus increase crew frustration. Therefore, the Habitability and Human Factors and Human Interface Branches at the NASA Johnson Space Center (JSC) are currently investigating a commercial-off-the-shelf (COTS) wireless communication system, Vocera(C), as a near-term solution for ISS communication. The objectives of the acoustics and intelligibility testing of this system were to answer the following questions: 1. How intelligibly can a human hear the transmitted message from a Vocera(c) badge in three different noise environments (Baseline = 20 dB, US Lab Module = 58 dB, Russian Module = 70.6 dB)? 2. How accurate is the Vocera(C) badge at recognizing voice commands in three different noise environments? 3. What body location (chest, upper arm, or shoulder) is optimal for speech intelligibility and voice recognition accuracy of the Vocera(C) badge on a human in three different noise environments?

  8. 5 Percent Ares I Scale Model Acoustic Test: Overpressure Characterization and Analysis

    NASA Technical Reports Server (NTRS)

    Alvord, David; Casiano, Matthew; McDaniels, Dave

    2011-01-01

    During the ignition of a ducted solid rocket motor (SRM), rapid expansion of injected hot gases from the motor into a confined volume causes the development of a steep fronted wave. This low frequency transient wave propagates outward from the exhaust duct, impinging the vehicle and ground structures. An unsuppressed overpressure wave can potentially cause modal excitation in the structures and vehicle, subsequently leading to damage. This presentation details the ignition transient f indings from the 5% Ares I Scale Model Acoustic Test (ASMAT). The primary events of the ignition transient environment induced by the SRM are the ignition overpressure (IOP), duct overpressure (DOP), and source overpressure (SOP). The resulting observations include successful knockdown of the IOP environment through use of a Space Shuttle derived IOP suppression system, a potential load applied to the vehicle stemming from instantaneous asymmetrical IOP and DOP wave impingement, and launch complex geometric influences on the environment. The results are scaled to a full-scale Ares I equivalent and compared with heritage data including Ares I-X and both suppressed and unsuppressed Space Shuttle IOP environments.

  9. Lobed Mixer Design for Noise Suppression Acoustic and Aerodynamic Test Data Analysis

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G.; Dalton, William N.; Boyd, Kathleen (Technical Monitor); Bridges, James (Technical Monitor)

    2002-01-01

    A comprehensive database for the acoustic and aerodynamic characteristics of several model-scale lobe mixers of bypass ratio 5 to 6 has been created for mixed jet speeds up to 1080 ft/s at typical take-off (TO) conditions of small-to-medium turbofan engines. The flight effect was simulated for Mach numbers up to 0.3. The static thrust performance and plume data were also obtained at typical TO and cruise conditions. The tests were done at NASA Lewis anechoic dome and ASK's FluiDyne Laboratories. The effect of several lobe mixer and nozzle parameters, such as, lobe scalloping, lobe count, lobe penetration and nozzle length was examined in terms of flyover noise at constant altitude. Sound in the nozzle reference frame was analyzed to understand the source characteristics. Several new concepts, mechanisms and methods are reported for such lobed mixers, such as, "boomerang" scallops, "tongue" mixer, detection of "excess" internal noise sources, and extrapolation of flyover noise data from one flight speed to different flight speeds. Noise reduction of as much as 3 EPNdB was found with a deeply scalloped mixer compared to annular nozzle at net thrust levels of 9500 lb for a 29 in. diameter nozzle after optimizing the nozzle length.

  10. Aerodynamic and Acoustic Tests of a 1/15 Scale Model Dry Cooled Jet Aircraft Runup Noise Suppression System,

    DTIC Science & Technology

    1975-10-01

    Temperature Contours for the Obround Augmenter with the Jet Centered (Position a, yp = 1.0) and Deflected Downward 3.60 165 Figure 7.3- 16 . Maximum Mixed...Acoustic Tests -8- r7 FLUIDYNE ENGINEERING CORPORATION I 2.0.3 Aero-Thermal Testing (Test Series 13 through 16 ) I The aero-thermal testing, Figure...Excessive Augmenter Exit Flow Noise Noise One Engine at Two Engines at Criteria Max. RPM Max. RPM at 250 ft. AA/ANT a AA/A NT 95 dBA 18 16 85 dBA 24

  11. Reproducibility experiments on measuring acoustical properties of rigid-frame porous media (round-robin tests).

    PubMed

    Horoshenkov, Kirill V; Khan, Amir; Bécot, François-Xavier; Jaouen, Luc; Sgard, Franck; Renault, Amélie; Amirouche, Nesrine; Pompoli, Francesco; Prodi, Nicola; Bonfiglio, Paolo; Pispola, Giulio; Asdrubali, Francesco; Hübelt, Jörn; Atalla, Noureddine; Amédin, Celse K; Lauriks, Walter; Boeckx, Laurens

    2007-07-01

    This paper reports the results of reproducibility experiments on the interlaboratory characterization of the acoustical properties of three types of consolidated porous media: granulated porous rubber, reticulated foam, and fiberglass. The measurements are conducted in several independent laboratories in Europe and North America. The studied acoustical characteristics are the surface complex acoustic impedance at normal incidence and plane wave absorption coefficient which are determined using the standard impedance tube method. The paper provides detailed procedures related to sample preparation and installation and it discusses the dispersion in the acoustical material property observed between individual material samples and laboratories. The importance of the boundary conditions, homogeneity of the porous material structure, and stability of the adopted signal processing method are highlighted.

  12. High intensity acoustic tests of a thermally stressed aluminum plate in TAFA

    NASA Technical Reports Server (NTRS)

    Ng, Chung Fai; Clevenson, Sherman A.

    1989-01-01

    An investigation was conducted in the Thermal Acoustic Fatigue Apparatus at the Langley Research Center to study the acoustically excited random motion of an aluminum plate which is buckled due to thermal stresses. The thermal buckling displacements were measured and compared with theory. The general trends of the changes in resonances frequencies and random responses of the plate agree with previous theoretical prediction and experimental results for a mechanically buckled plate.

  13. AMADEUS—The acoustic neutrino detection test system of the ANTARES deep-sea neutrino telescope

    NASA Astrophysics Data System (ADS)

    Aguilar, J. A.; Al Samarai, I.; Albert, A.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Assis Jesus, A. C.; Astraatmadja, T.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Baret, B.; Basa, S.; Bazzotti, M.; Bertin, V.; Biagi, S.; Bigongiari, C.; Bou-Cabo, M.; Bouwhuis, M. C.; Brown, A.; Brunner, J.; Busto, J.; Camarena, F.; Capone, A.; Cârloganu, C.; Carminati, G.; Carr, J.; Cassano, B.; Castorina, E.; Cavasinni, V.; Cecchini, S.; Ceres, A.; Charvis, Ph.; Chiarusi, T.; Chon Sen, N.; Circella, M.; Coniglione, R.; Costantini, H.; Cottini, N.; Coyle, P.; Curtil, C.; de Bonis, G.; Decowski, M. P.; Dekeyser, I.; Deschamps, A.; Distefano, C.; Donzaud, C.; Dornic, D.; Drouhin, D.; Eberl, T.; Emanuele, U.; Ernenwein, J.-P.; Escoffier, S.; Fehr, F.; Fiorello, C.; Flaminio, V.; Fritsch, U.; Fuda, J.-L.; Gay, P.; Giacomelli, G.; Gómez-González, J. P.; Graf, K.; Guillard, G.; Halladjian, G.; Hallewell, G.; van Haren, H.; Heijboer, A. J.; Heine, E.; Hello, Y.; Hernández-Rey, J. J.; Herold, B.; Hößl, J.; de Jong, M.; Kalantar-Nayestanaki, N.; Kalekin, O.; Kappes, A.; Katz, U.; Keller, P.; Kooijman, P.; Kopper, C.; Kouchner, A.; Kretschmer, W.; Lahmann, R.; Lamare, P.; Lambard, G.; Larosa, G.; Laschinsky, H.; Le Provost, H.; Lefèvre, D.; Lelaizant, G.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Lucarelli, F.; Mangano, S.; Marcelin, M.; Margiotta, A.; Martinez-Mora, J. A.; Mazure, A.; Mongelli, M.; Montaruli, T.; Morganti, M.; Moscoso, L.; Motz, H.; Naumann, C.; Neff, M.; Ostasch, R.; Palioselitis, D.; Păvălaş, G. E.; Payre, P.; Petrovic, J.; Picot-Clemente, N.; Picq, C.; Popa, V.; Pradier, T.; Presani, E.; Racca, C.; Radu, A.; Reed, C.; Riccobene, G.; Richardt, C.; Rujoiu, M.; Ruppi, M.; Russo, G. V.; Salesa, F.; Sapienza, P.; Schöck, F.; Schuller, J.-P.; Shanidze, R.; Simeone, F.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th.; Taiuti, M.; Tamburini, C.; Tasca, L.; Toscano, S.; Vallage, B.; van Elewyck, V.; Vannoni, G.; Vecchi, M.; Vernin, P.; Wijnker, G.; de Wolf, E.; Yepes, H.; Zaborov, D.; Zornoza, J. D.; Zúñiga, J.

    2011-01-01

    The AMADEUS (ANTARES Modules for the Acoustic Detection Under the Sea) system which is described in this article aims at the investigation of techniques for acoustic detection of neutrinos in the deep sea. It is integrated into the ANTARES neutrino telescope in the Mediterranean Sea. Its acoustic sensors, installed at water depths between 2050 and 2300 m, employ piezo-electric elements for the broad-band recording of signals with frequencies ranging up to 125 kHz. The typical sensitivity of the sensors is around -145 dB re 1 V/μPa (including preamplifier). Completed in May 2008, AMADEUS consists of six “acoustic clusters”, each comprising six acoustic sensors that are arranged at distances of roughly 1 m from each other. Two vertical mechanical structures (so-called lines) of the ANTARES detector host three acoustic clusters each. Spacings between the clusters range from 14.5 to 340 m. Each cluster contains custom-designed electronics boards to amplify and digitise the acoustic signals from the sensors. An on-shore computer cluster is used to process and filter the data stream and store the selected events. The daily volume of recorded data is about 10 GB. The system is operating continuously and automatically, requiring only little human intervention. AMADEUS allows for extensive studies of both transient signals and ambient noise in the deep sea, as well as signal correlations on several length scales and localisation of acoustic point sources. Thus the system is excellently suited to assess the background conditions for the measurement of the bipolar pulses expected to originate from neutrino interactions.

  14. Acoustic flight test experience with the XV-15 Tiltrotor aircraft with the Advanced Technology Blade (ATB)

    NASA Technical Reports Server (NTRS)

    Hoad, Danny R.; Conner, David A.; Rutledge, Charles K.

    1992-01-01

    An acoustic model that predicts the discrete frequency noise characteristics of helicopter rotors has been utilized in an analysis to help identify source characteristics. This technique incorporated a NASA Langley developed acoustic prediction technique, and a simplified flow field model to account for rotor wake reingestion in hover. The vehicle rotor system was modified to include the ATBs that were designed to provide for higher operating weights and improved maneuver load factor in helicopter and transition modes of operation.

  15. Test of an Acoustic Mechanism for Atmospheric Heating in Dynamo-Deficient F Stars

    NASA Technical Reports Server (NTRS)

    Mullan, D. J.

    1996-01-01

    In a qualitative sense, the heating of chromospheres and coronae has long been ascribed to either acoustic or magnetic heating. However, quantitative discussions of the energy balance with detailed comparison to the fluxes of chromospheric emission lines have begun to appear only recently. The aim of this work is to observe F stars where magnetic effects might be expected to be rather small, thereby allowing us hopefully to access acoustically heated atmospheres.

  16. A methodology to condition distorted acoustic emission signals to identify fracture timing from human cadaver spine impact tests.

    PubMed

    Arun, Mike W J; Yoganandan, Narayan; Stemper, Brian D; Pintar, Frank A

    2014-12-01

    While studies have used acoustic sensors to determine fracture initiation time in biomechanical studies, a systematic procedure is not established to process acoustic signals. The objective of the study was to develop a methodology to condition distorted acoustic emission data using signal processing techniques to identify fracture initiation time. The methodology was developed from testing a human cadaver lumbar spine column. Acoustic sensors were glued to all vertebrae, high-rate impact loading was applied, load-time histories were recorded (load cell), and fracture was documented using CT. Compression fracture occurred to L1 while other vertebrae were intact. FFT of raw voltage-time traces were used to determine an optimum frequency range associated with high decibel levels. Signals were bandpass filtered in this range. Bursting pattern was found in the fractured vertebra while signals from other vertebrae were silent. Bursting time was associated with time of fracture initiation. Force at fracture was determined using this time and force-time data. The methodology is independent of selecting parameters a priori such as fixing a voltage level(s), bandpass frequency and/or using force-time signal, and allows determination of force based on time identified during signal processing. The methodology can be used for different body regions in cadaver experiments.

  17. Acoustic neuroma

    MedlinePlus

    Vestibular schwannoma; Tumor - acoustic; Cerebellopontine angle tumor; Angle tumor; Hearing loss - acoustic; Tinnitus - acoustic ... Acoustic neuromas have been linked with the genetic disorder neurofibromatosis type 2 (NF2). Acoustic neuromas are uncommon.

  18. Acoustic tests on a new motor generator system for the Minuteman launch control centers at Alpha 01 and Sierra 00, Malmstrom AFB, Montana

    NASA Astrophysics Data System (ADS)

    Fairman, Terry M.

    1991-05-01

    Field tests of the acoustic performance of a new motor generator system (MGS) were performed at Minuteman Launch Control Centers (LCC) Alpha 01 and Sierra 00, Malmstrom AFB, MT. This same MGS unit was accepted for use after the Hill Engineering Test Facilities (HETF) acoustic performance studies conducted in 1988. Rivet Mile from the Ogden ALC began installation of the new MGS at Malmstrom in the spring of 1990. Performance tests were requested by 00-ALC/MMGRMM, and SAC, to compare with the HETF data and document the LCC acoustic environment with the new MGS operating in a field setting. This report presents our findings.

  19. Nondestructive testing: use of IR and acoustics methods in buildings pathology

    NASA Astrophysics Data System (ADS)

    Esposti, Walter; Meroni, Italo

    1995-03-01

    In the paper the authors present some experiences made using IR and acoustics methods in a non destructive way for the evaluation of situations of degradation in building materials and components. Two studies are presented: (1) detection of the delamination of wall renderings, especially those supporting frescos, by means of IR and sonic investigation; (2) use of infrared thermography for the visualization of fracture zones of walls and steel components under cyclic loads. The possibility of detecting rendering delaminations is based on the different path of the heat diffusion in part of the wall affected by the delamination, compared to the rest of the wall. The difference is caused by the presence of small pockets containing still air. The case study showed makes reference to the analysis of adhesion conditions of a rendering dating back to the IV century, applied on the bell towers of the ancient basilica dedicated to S. Lorenzo in Milan, Italy. The use of infrared thermography for detecting the strength status of materials and components is based on the fact that the strength status of parts of building components can become evident because of heat losses which appear where the component is weaker. The IR observation was made on steel bars subject to traction testing and on lightweight concrete prismatic samples subject to compression testing. The experiences indicate that there is room for this NdT technique to provide some useful answers. Nevertheless it is sure that more experimental work is needed in order to increase the full comprehension of the phenomena which are the basis of their applications for alternative uses.

  20. The anthraquinone derivative emodin attenuates methamphetamine-induced hyperlocomotion and startle response in rats.

    PubMed

    Mizuno, Makoto; Kawamura, Hiroki; Ishizuka, Yuta; Sotoyama, Hidekazu; Nawa, Hiroyuki

    2010-12-01

    Abnormal signaling mediated by epidermal growth factor (EGF) or its receptor (ErbB) is implicated in the neuropathology of schizophrenia. Previously, we found that the anthraquinone derivative emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits ErbB1 signaling and ameliorates behavioral deficits of the schizophrenia animal model established by EGF challenge. In the present study, we assessed acute and subchronic effects of its administration on methamphetamine-triggered behavioral hyperactivation in rats. Prior subchronic administration of emodin (50mg/kg/day, 5days, p.o.) suppressed both higher acoustic startle responses and hyperlocomotion induced by acute methamphetamine challenge. In parallel, emodin also attenuated methamphetamine-induced increases in dopamine and its metabolites and decreases in serotonin and its metabolites. Emodin administered alone also had an effect on stereotypic movement but no influence on horizontal or vertical locomotor activity. In contrast to pre-treatment, post-treatment with emodin had no effect on behavioral sensitization to methamphetamine. Administration of emodin in parallel to or following repeated methamphetamine challenge failed to affect hyperlocomotion induced by methamphetamine re-challenges. These findings suggest that emodin has unique pharmacological activity, which interferes with acute methamphetamine signaling and behavior.

  1. Examining habituation of the startle reflex with the reinforcement sensitivity theory of personality.

    PubMed

    Blanch, Angel; Aluja, Anton; Blanco, Eduardo; Balada, Ferran

    2016-10-01

    The habituation of the acoustic startle reflex (ASR) was examined concerning individual differences in sensitivity to punishment (PUN) and sensitivity to reward (REW), within the general framework of the reinforcement sensitivity theory (RST) of personality. Two hypotheses derived from the RST were evaluated: the separable subsystems hypothesis and the joint subsystems hypothesis. In addition, we examined the direction of the relationship of PUN and REW with the habituation of the ASR. A habituation segment of electromyography recordings of the orbicularis oculi was assessed with an unconditional latent curve model. In accordance with the RST hypotheses, the relationship of PUN and REW on the habituation process was assessed with two conditional latent curve models. There was higher support for the separable subsystems hypothesis. In addition, PUN and REW related with the habituation trajectory of the ASR in the expected directions. Higher levels of PUN and lower levels of REW related with a slower habituation of the ASR, whereas lower levels of PUN and higher levels of REW related with a faster habituation of the ASR.

  2. Validation and Simulation of Ares I Scale Model Acoustic Test - 2 - Simulations at 5 Foot Elevation for Evaluation of Launch Mount Effects

    NASA Technical Reports Server (NTRS)

    Strutzenberg, Louise L.; Putman, Gabriel C.

    2011-01-01

    The Ares I Scale Model Acoustics Test (ASMAT) is a series of live-fire tests of scaled rocket motors meant to simulate the conditions of the Ares I launch configuration. These tests have provided a well documented set of high fidelity measurements useful for validation including data taken over a range of test conditions and containing phenomena like Ignition Over-Pressure and water suppression of acoustics. Expanding from initial simulations of the ASMAT setup in a held down configuration, simulations have been performed using the Loci/CHEM computational fluid dynamics software for ASMAT tests of the vehicle at 5 ft. elevation (100 ft. real vehicle elevation) with worst case drift in the direction of the launch tower. These tests have been performed without water suppression and have compared the acoustic emissions for launch structures with and without launch mounts. In addition, simulation results have also been compared to acoustic and imagery data collected from similar live-fire tests to assess the accuracy of the simulations. Simulations have shown a marked change in the pattern of emissions after removal of the launch mount with a reduction in the overall acoustic environment experienced by the vehicle and the formation of highly directed acoustic waves moving across the platform deck. Comparisons of simulation results to live-fire test data showed good amplitude and temporal correlation and imagery comparisons over the visible and infrared wavelengths showed qualitative capture of all plume and pressure wave evolution features.

  3. Computational Analyses in Support of Sub-scale Diffuser Testing for the A-3 Facility. Part 3; Aero-Acoustic Analyses and Experimental Validation

    NASA Technical Reports Server (NTRS)

    Allgood, Daniel C.; Graham, Jason S.; McVay, Greg P.; Langford, Lester L.

    2008-01-01

    A unique assessment of acoustic similarity scaling laws and acoustic analogy methodologies in predicting the far-field acoustic signature from a sub-scale altitude rocket test facility at the NASA Stennis Space Center was performed. A directional, point-source similarity analysis was implemented for predicting the acoustic far-field. In this approach, experimental acoustic data obtained from "similar" rocket engine tests were appropriately scaled using key geometric and dynamic parameters. The accuracy of this engineering-level method is discussed by comparing the predictions with acoustic far-field measurements obtained. In addition, a CFD solver was coupled with a Lilley's acoustic analogy formulation to determine the improvement of using a physics-based methodology over an experimental correlation approach. In the current work, steady-state Reynolds-averaged Navier-Stokes calculations were used to model the internal flow of the rocket engine and altitude diffuser. These internal flow simulations provided the necessary realistic input conditions for external plume simulations. The CFD plume simulations were then used to provide the spatial turbulent noise source distributions in the acoustic analogy calculations. Preliminary findings of these studies will be discussed.

  4. Durability assessments of concrete using electrical properties and acoustic emission testing

    NASA Astrophysics Data System (ADS)

    Todak, Heather N.

    Premature damage deterioration has been observed in pavement joints throughout the Midwestern region of the United States. Over time, severe joint damage creates a transportation safety concern and the necessary repairs can be an extreme economic burden. The deterioration is due in part to freeze-thaw damage associated with fluid accumulation at the pavement joints. This very preventable problem is an indication that current specifications and construction practices for freeze-thaw durability of concrete are inadequate. This thesis serves to create a better understanding of moisture ingress, freeze-thaw damage mechanisms, and the effect of variations in mixture properties on freeze-thaw behavior of concrete. The concepts of the nick point degree of saturation, sorptivity rates, and critical degree of saturation are discussed. These factors contribute to service life, defined in this study as the duration of time a concrete element remains below levels of critical saturation which are required for damage development to initiate. A theoretical model and a simple experimental procedure are introduced which help determine the nick point for a series of 32 concrete mixtures with unique mixture proportions and air entrainment properties. This simple experimental procedure is also presented as a method to measure important electrical properties in order to establish the formation factor, a valuable measure of concrete transport properties. The results of freeze-thaw testing with acoustic emission monitoring are presented to help understand and quantify damage development in concrete specimens when conditioned to various degrees of saturation. This procedure was used to study the relationship between air entrainment properties and the critical degree of saturation. Applying the concepts of degree of saturation and sorptivity, a performance-based model is proposed as a new approach to specifications for freeze-thaw durability. Finally, a conceptual model is presented to

  5. Whiplash evokes descending muscle recruitment and sympathetic responses characteristic of startle

    PubMed Central

    Mang, Daniel WH; Siegmund, Gunter P; Blouin, Jean-Sébastien

    2014-01-01

    Whiplash injuries are the most common injuries following rear-end collisions. During a rear-end collision, the human muscle response consists of both a postural and a startle response that may exacerbate injury. However, most previous studies only assessed the presence of startle using data collected from the neck muscles and head/neck kinematics. The startle response also evokes a descending pattern of muscle recruitment and changes in autonomic activity. Here we examined the recruitment of axial and appendicular muscles along with autonomic responses to confirm whether these other features of a startle response were present during the first exposure to a whiplash perturbation. Ten subjects experienced a single whiplash perturbation while recording electromyography, electrocardiogram, and electrodermal responses. All subjects exhibited a descending pattern of muscle recruitment, and increasing heart rate and electrodermal responses following the collision. Our results provide further support that the startle response is a component of the response to whiplash collisions. PMID:24932015

  6. Whiplash evokes descending muscle recruitment and sympathetic responses characteristic of startle.

    PubMed

    Mang, Daniel Wh; Siegmund, Gunter P; Blouin, Jean-Sébastien

    2014-06-01

    Whiplash injuries are the most common injuries following rear-end collisions. During a rear-end collision, the human muscle response consists of both a postural and a startle response that may exacerbate injury. However, most previous studies only assessed the presence of startle using data collected from the neck muscles and head/neck kinematics. The startle response also evokes a descending pattern of muscle recruitment and changes in autonomic activity. Here we examined the recruitment of axial and appendicular muscles along with autonomic responses to confirm whether these other features of a startle response were present during the first exposure to a whiplash perturbation. Ten subjects experienced a single whiplash perturbation while recording electromyography, electrocardiogram, and electrodermal responses. All subjects exhibited a descending pattern of muscle recruitment, and increasing heart rate and electrodermal responses following the collision. Our results provide further support that the startle response is a component of the response to whiplash collisions.

  7. Development and testing of cabin sidewall acoustic resonators for the reduction of cabin tone levels in propfan-powered aircraft

    NASA Technical Reports Server (NTRS)

    Kuntz, H. L.; Gatineau, R. J.; Prydz, R. A.; Balena, F. J.

    1991-01-01

    The use of Helmholtz resonators to increase the sidewall transmission loss (TL) in aircraft cabin sidewalls is evaluated. Development, construction, and test of an aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Laboratory and flight test results are discussed. Resonators (448) were located between the enclosure trim panels and the fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a propfan fundamental blade passage frequency (235 Hz). After flight testing on the PTA aircraft, noise reduction (NR) tests were performed with the enclosure in the Kelly Johnson Research and Development Center Acoustics Laboratory. Broadband and tonal excitations were used in the laboratory. Tonal excitation simulated the propfan flight test excitation. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. Increases in NR of up to 11 dB were measured. The effects of flanking, sidewall absorption, cabin absorption, resonator loading of trim panels, and panel vibrations are presented. Resonator and sidewall panel design and test are discussed.

  8. Acoustic Data Processing and Transient Signal Analysis for the Hybrid Wing Body 14- by 22-Foot Subsonic Wind Tunnel Test

    NASA Technical Reports Server (NTRS)

    Bahr, Christopher J.; Brooks, Thomas F.; Humphreys, William M.; Spalt, Taylor B.; Stead, Daniel J.

    2014-01-01

    An advanced vehicle concept, the HWB N2A-EXTE aircraft design, was tested in NASA Langley's 14- by 22-Foot Subsonic Wind Tunnel to study its acoustic characteristics for var- ious propulsion system installation and airframe con gurations. A signi cant upgrade to existing data processing systems was implemented, with a focus on portability and a re- duction in turnaround time. These requirements were met by updating codes originally written for a cluster environment and transferring them to a local workstation while en- abling GPU computing. Post-test, additional processing of the time series was required to remove transient hydrodynamic gusts from some of the microphone time series. A novel automated procedure was developed to analyze and reject contaminated blocks of data, under the assumption that the desired acoustic signal of interest was a band-limited sta- tionary random process, and of lower variance than the hydrodynamic contamination. The procedure is shown to successfully identify and remove contaminated blocks of data and retain the desired acoustic signal. Additional corrections to the data, mainly background subtraction, shear layer refraction calculations, atmospheric attenuation and microphone directivity corrections, were all necessary for initial analysis and noise assessments. These were implemented for the post-processing of spectral data, and are shown to behave as expected.

  9. Towards Truly Quiet MRI: animal MRI magnetic field gradients as a test platform for acoustic noise reduction

    NASA Astrophysics Data System (ADS)

    Edelstein, William; El-Sharkawy, Abdel-Monem

    2013-03-01

    Clinical MRI acoustic noise, often substantially exceeding 100 dB, causes patient anxiety and discomfort and interferes with functional MRI (fMRI) and interventional MRI. MRI acoustic noise reduction is a long-standing and difficult technical challenge. The noise is basically caused by large Lorentz forces on gradient windings--surrounding the patient bore--situated in strong magnetic fields (1.5 T, 3 T or higher). Pulsed currents of 300 A or more are switched through the gradient windings in sub-milliseconds. Experimenting with hardware noise reduction on clinical scanners is difficult and expensive because of the large scale and weight of clinical scanner components (gradient windings ~ 1000 kg) that require special handling equipment in large engineering test facilities. Our approach is to produce a Truly Quiet (<70 dB) small-scale animal imager. Results serve as a test platform for acoustic noise reduction measures that can be implemented in clinical scanners. We have so far decreased noise in an animal scale imager from 108 dB to 71 dB, a 37 dB reduction. Our noise reduction measures include: a gradient container that can be evacuated; inflatable antivibration mounts to prevent transmission of vibrations from gradient winding to gradient container; vibration damping of wires going from gradient to the outside world via the gradient container; and a copper passive shield to prevent the generation of eddy currents in the metal cryostat inner bore, which in turn can vibrate and produce noise.

  10. Chronic jet lag impairs startle-induced locomotion in Drosophila.

    PubMed

    Vaccaro, Alexandra; Birman, Serge; Klarsfeld, André

    2016-12-01

    Endogenous circadian clocks with ~24-h periodicity are found in most organisms from cyanobacteria to humans. Daylight synchronizes these clocks to solar time. In humans, shift-work and jet lag perturb clock synchronization, and such perturbations, when repeated or chronic, are strongly suspected to be detrimental to healthspan. Here we investigated locomotor aging and longevity in Drosophila melanogaster with genetically or environmentally disrupted clocks. We compared two mutations in period (per, a gene essential for circadian rhythmicity in Drosophila), after introducing them in a common reference genetic background: the arrhythmic per(01), and per(T) which displays robust short 16-h rhythms. Compared to the wild type, both per mutants showed reduced longevity and decreased startle-induced locomotion in aging flies, while spontaneous locomotor activity was not impaired. The per(01) phenotypes were generally less severe than those of per(T), suggesting that chronic jet lag is more detrimental to aging than arrhythmicity in Drosophila. Interestingly, the adjustment of environmental light-dark cycles to the endogenous rhythms of the per(T) mutant fully suppressed the acceleration in the age-related decline of startle-induced locomotion, while it accelerated this decline in wild-type flies. Overall, our results show that chronic jet lag accelerates a specific form of locomotor aging in Drosophila, and that this effect can be alleviated by environmental changes that ameliorate circadian rhythm synchronization.

  11. Untangling the effects of tinnitus and hypersensitivity to sound (hyperacusis) in the gap detection test.

    PubMed

    Salloum, R H; Sandridge, S; Patton, D J; Stillitano, G; Dawson, G; Niforatos, J; Santiago, L; Kaltenbach, J A

    2016-01-01

    In recent years, there has been increasing use of the gap detection reflex test to demonstrate induction of tinnitus in animals. Animals with tinnitus show weakened gap detection ability for background noise that matches the pitch of the tinnitus. The usual explanation is that the tinnitus 'fills in the gap'. It has recently been shown, however, that tinnitus is commonly associated with hyperacusis-like enhancements of the acoustic startle response, a change which might potentially alter responses in the gap detection test. We hypothesized that such enhancements could lead to an apparent reduction of gap suppression, resembling that caused by tinnitus, by altering responses to the startle stimulus or the background noise. To test this hypothesis, we compared gap detection abilities in 3 subsets of noise-exposed animals with those in unexposed controls. The results showed that exposed animals demonstrated altered gap detection abilities, but these alterations were sometimes explained as consequences of hyper-responsiveness to either the startle stimulus or to the background noise. Two of the three subsets of animals studied, however, displayed weakened gap detection abilities that could not be explained by enhanced responses to these stimuli or by reduced sound sensitivity or a reduction of temporal processing speed, consistent with the induction of tinnitus. These results demonstrate that not only hearing loss but also changes in sensitivity to background noise or to startle stimuli are potential confounds that, when present, can underlie changes in gap detection irrespective of tinnitus. We discuss how such confounds can be recognized and how they can be avoided.

  12. Preliminary vibration, acoustic, and shock design and test criteria for components on the SRB, ET, and SSME

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Specifications for vibration, acoustic and shock design for components and subassemblies on the External Tank (ET), Solid Rocket Booster (SRB), and Space Shuttle Main Engine (SSME). Included are vibration, acoustic, shock, transportation, handling, and acceptance test requirements and procedures. The space shuttle ET, SRB, and SSME have been divided into zones and subzones. Zones are designated primarily to assist in determining the applicable specifications. A subzone (General Specification) is available for use when the location of the component is known but component design and weight are not well defined. When the location, weight, and mounting configuration of the component are known, specifications for appropriate subzone weight ranges are available. Criteria for some specific components are also presented.

  13. Acoustic emission analysis: A test method for metal joints bonded by adhesives

    NASA Technical Reports Server (NTRS)

    Brockmann, W.; Fischer, T.

    1978-01-01

    Acoustic emission analysis is applied to study adhesive joints which had been subjected to mechanical and climatic stresses, taking into account conditions which make results applicable to adhesive joints used in aerospace technology. Specimens consisting of the alloy AlMgSi0.5 were used together with a phenolic resin adhesive, an epoxy resin modified with a polyamide, and an epoxy resin modified with a nitrile. Results show that the acoustic emission analysis provides valuable information concerning the behavior of adhesive joints under load and climatic stresses.

  14. Quantitative Measures of Anthropogenic Noise on Harbor Porpoises: Testing the Reliability of Acoustic Tag Recordings.

    PubMed

    Wisniewska, Danuta M; Teilmann, Jonas; Hermannsen, Line; Johnson, Mark; Miller, Lee A; Siebert, Ursula; Madsen, Peter Teglberg

    2016-01-01

    In recent years, several sound and movement recording tags have been developed to sample the acoustic field experienced by cetaceans and their reactions to it. However, little is known about how tag placement and an animal's orientation in the sound field affect the reliability of on-animal recordings as proxies for actual exposure. Here, we quantify sound exposure levels recorded with a DTAG-3 tag on a captive harbor porpoise exposed to vessel noise in a controlled acoustic environment. Results show that flow noise is limiting onboard noise recordings, whereas no evidence of body shading has been found for frequencies of 2-20 kHz.

  15. Acoustic emission frequency discrimination

    NASA Technical Reports Server (NTRS)

    Sugg, Frank E. (Inventor); Graham, Lloyd J. (Inventor)

    1988-01-01

    In acoustic emission nondestructive testing, broadband frequency noise is distinguished from narrow banded acoustic emission signals, since the latter are valid events indicative of structural flaws in the material being examined. This is accomplished by separating out those signals which contain frequency components both within and beyond (either above or below) the range of valid acoustic emission events. Application to acoustic emission monitoring during nondestructive bond verification and proof loading of undensified tiles on the Space Shuttle Orbiter is considered.

  16. Navy vehicles: acoustic emission related to nondestructive testing. Final report, 1980-1987

    SciTech Connect

    Ono, K.

    1988-04-12

    This investigation was aimed at studying acoustic emission for applications to residual stress measurements and for the evaluation of structural integrity of engineering structures. Effects of microstructure, composition and prior cold working on magnetomechanical acoustic emission(MAE) have been studied. Magnetization behavior, magnetostriction and Barkhausen noise are affected by stress as well as other parameters. These responses have been measured simultaneously in order to identify the stress level uniquely. Combinations of advanced signal analysis methods and MAE measurements have been studied to identify the optimum parameters for applications. This work has established mechanisms of MAE signal generation, effects of various parameters that influence the MAE behavior of materials and signal processing techniques that allow materials characterization via MAE. Included are neutron-irradiated reactor-vessel steels, large-size steel plates as well as single crystals of various ferromagnetic metals and alloys. In the second part of this study, acoustic emission from materials undergoing plastic deformation and fracture were examined in an attempt to improve detection capability of the impending structural failure. Acoustic emission characteristics of reactor-vessel steels, advanced aluminum alloys and metal and ceramic-matrix composite materials have been evaluated in detail.

  17. Wideband Acoustic Immittance: Normative Study and Test-Retest Reliability of Tympanometric Measurements in Adults

    ERIC Educational Resources Information Center

    Sun, Xiao-Ming

    2016-01-01

    Purpose: The purpose of this study was to present normative data of tympanometric measurements of wideband acoustic immittance and to characterize wideband tympanograms. Method: Data were collected in 84 young adults with strictly defined normal hearing and middle ear status. Energy absorbance (EA) was measured using clicks for 1/12-octave…

  18. Experimental investigation of shock-cell noise reduction for dual-stream nozzles in simulated flight comprehensive data report. Volume 1: Test nozzles and acoustic data

    NASA Technical Reports Server (NTRS)

    Yamamoto, K.; Janardan, B. A.; Brausch, J. F.; Hoerst, D. J.; Price, A. O.

    1984-01-01

    Parameters which contribute to supersonic jet shock noise were investigated for the purpose of determining means to reduce such noise generation to acceptable levels. Six dual-stream test nozzles with varying flow passage and plug closure designs were evaluated under simulated flight conditions in an anechoic chamber. All nozzles had combined convergent-divergent or convergent flow passages. Acoustic behavior as a function of nozzle flow passage geometry was measured. The acoustic data consist primarily of 1/3 octave band sound pressure levels and overall sound pressure levels. Detailed schematics and geometric characteristics of the six scale model nozzle configurations and acoustic test point definitions are presented. Tabulation of aerodynamic test conditions and a computer listing of the measured acoustic data are displayed.

  19. Comparison of vestibular and auditory startle responses in the rat and cat.

    PubMed

    Gruner, J A

    1989-02-01

    Cats, humans, and many other animals show stereotyped EMG responses in limb and axial muscles if suddenly dropped into free-fall. In cats, these free-fall responses (FFR) consist of highly synchronized bursts in most limb and axial muscles at 18-22 ms. We have used FFR to evaluate descending motor function and recovery in chronic spinal injured cats. Here FFR are compared with auditory evoked startle reflexes (ASR) in the hindlimb muscles of the rat and cat to determine whether they are related, and whether they could be used to evaluate descending motor function in the rat. ASR and FFR in the two species were similar except that the earliest components for both responses occurred around 9 ms in the rat versus 18-20 ms in the cat. Also, FFR in cats were usually more consistent and greater in amplitude during repeated drops than in rats, while the converse was true for ASR. Rat FFR amplitudes increased significantly after administering ketamine or 4-aminopyridine (4-AP), especially with both drugs together, while ASR amplitudes did not. FFR in cats recorded under ketamine analgesia were not normally improved by 4-AP. Finally, both FFR and ASR were suppressed by pentobarbital, chloralose, or motor activity. These data suggest that: (1) FFR appears to be a vestibular evoked startle reflex; (2) in the rat, ASR should be useful as a test of descending motor function following spinal injury, and (3) the combination of ketamine and 4-AP may be useful in revealing the presence of functional spinal pathways after CNS trauma.

  20. AMELIA CESTOL Test: Acoustic Characteristics of Circulation Control Wing with Leading- and Trailing-Edge Slot Blowing

    NASA Technical Reports Server (NTRS)

    Horne, William C.; Burnside, Nathan J.

    2013-01-01

    The AMELIA Cruise-Efficient Short Take-off and Landing (CESTOL) configuration concept was developed to meet future requirements of reduced field length, noise, and fuel burn by researchers at Cal Poly, San Luis Obispo and Georgia Tech Research Institute under sponsorship by the NASA Fundamental Aeronautics Program (FAP), Subsonic Fixed Wing Project. The novel configuration includes leading- and trailing-edge circulation control wing (CCW), over-wing podded turbine propulsion simulation (TPS). Extensive aerodynamic measurements of forces, surfaces pressures, and wing surface skin friction measurements were recently measured over a wide range of test conditions in the Arnold Engineering Development Center(AEDC) National Full-Scale Aerodynamics Complex (NFAC) 40- by 80-Ft Wind Tunnel. Acoustic measurements of the model were also acquired for each configuration with 7 fixed microphones on a line under the left wing, and with a 48-element, 40-inch diameter phased microphone array under the right wing. This presentation will discuss acoustic characteristics of the CCW system for a variety of tunnel speeds (0 to 120 kts), model configurations (leading edge(LE) and/or trailing-edge(TE) slot blowing, and orientations (incidence and yaw) based on acoustic measurements acquired concurrently with the aerodynamic measurements. The flow coefficient, Cmu= mVSLOT/qSW varied from 0 to 0.88 at 40 kts, and from 0 to 0.15 at 120 kts. Here m is the slot mass flow rate, VSLOT is the slot exit velocity, q is dynamic pressure, and SW is wing surface area. Directivities at selected 1/3 octave bands will be compared with comparable measurements of a 2-D wing at GTRI, as will as microphone array near-field measurements of the right wing at maximum flow rate. The presentation will include discussion of acoustic sensor calibrations as well as characterization of the wind tunnel background noise environment.

  1. Acoustic tests on a new motor generator system for the minuteman launch control centers in Hill engineering test facilities 1 and 2, Hill AFB, Utah

    NASA Astrophysics Data System (ADS)

    Fairman, Terry M.

    1989-04-01

    Post critical design review acoustic tests were performed in Hill Engineering Test Facilities 1 and 2 (HETF) on a proposed new motor generator system for the Minuteman Launch Control Centers (LCC). A performance noise criteria equivalent to a preferred noise criterion (PNC-50) curve was established as the standard by which to judge the effectiveness of the new motor generator. Measurements were obtained at both the commander's console and the deputy commander's console. Results indicated the noise from the motor generator as configured in HETF 1 (the small LCC) exceeded the PNC-50 criteria primarily in the 63 hertz (Hz) octave band by 10 decibels (dB) when operated in both the ac and dc modes. The motor generator as configured in HETF 2 (the large LCC) exceeded the PNC-50 criteria by 3 dB in the 125 Hz octave band only at the deputy commander's console when operated in the ac mode. Acoustic intensity measurements were obtained to isolate specific noise sources and determine the transmission loss of the floor panels. Vibration measurements were also made on and near the motor generator to determine paths of structure-borne vibration energy. Specific recommendations for improving the acoustic environment in the LCC's are presented.

  2. Reflexes Inhibited by a Prepulse: Intensity of Startle Stimulus and Prepulse Across Onset Intervals.

    PubMed

    Nishiyama, Ryoji; Iso, Hiroyuki

    2016-08-01

    Prepulse inhibition refers to the inhibition of the startle reflexes by a weak stimulus (prepulse) that precedes a strong startle stimulus (pulse). Previous findings suggest that prepulse intensity affects prepulse inhibition amplitude and that prepulse inhibition amplitudes vary across onset intervals between the prepulse and pulse. However, evidence regarding the effect of startle stimulus intensity is still inconclusive, especially due to variations between prepulse inhibition scores calculated by using percentage-type and difference-type formulas. Moreover, the combined effect of startle stimulus and prepulse intensities across onset intervals remains poorly understood. The present study investigated the combined effect as well as the influence of startle response amplitudes on the formulae used for the calculation. The results suggest that startle stimulus intensity could potentially affect results of percentage-type formulae for calculating prepulse inhibition over a wide range of lead intervals. Furthermore, the results demonstrated that a combination of strong startle stimulus intensities and weak prepulse intensities could not induce prepulse inhibition at long onset intervals (1000 ms and 2000 ms).

  3. Hypnotizability and Placebo Analgesia in Waking and Hypnosis as Modulators of Auditory Startle Responses in Healthy Women: An ERP Study

    PubMed Central

    De Pascalis, Vilfredo; Scacchia, Paolo

    2016-01-01

    We evaluated the influence of hypnotizability, pain expectation, placebo analgesia in waking and hypnosis on tonic pain relief. We also investigated how placebo analgesia affects somatic responses (eye blink) and N100 and P200 waves of event-related potentials (ERPs) elicited by auditory startle probes. Although expectation plays an important role in placebo and hypnotic analgesia, the neural mechanisms underlying these treatments are still poorly understood. We used the cold cup test (CCT) to induce tonic pain in 53 healthy women. Placebo analgesia was initially produced by manipulation, in which the intensity of pain induced by the CCT was surreptitiously reduced after the administration of a sham analgesic cream. Participants were then tested in waking and hypnosis under three treatments: (1) resting (Baseline); (2) CCT-alone (Pain); and (3) CCT plus placebo cream for pain relief (Placebo). For each painful treatment, we assessed pain and distress ratings, eye blink responses, N100 and P200 amplitudes. We used LORETA analysis of N100 and P200 waves, as elicited by auditory startle, to identify cortical regions sensitive to pain reduction through placebo and hypnotic analgesia. Higher pain expectation was associated with higher pain reductions. In highly hypnotizable participants placebo treatment produced significant reductions of pain and distress perception in both waking and hypnosis condition. P200 wave, during placebo analgesia, was larger in the frontal left hemisphere while placebo analgesia, during hypnosis, involved the activity of the left hemisphere including the occipital region. These findings demonstrate that hypnosis and placebo analgesia are different processes of top-down regulation. Pain reduction was associated with larger EMG startle amplitudes, N100 and P200 responses, and enhanced activity within the frontal, parietal, and anterior and posterior cingulate gyres. LORETA results showed that placebo analgesia modulated pain-responsive areas

  4. Scale Model Acoustic Test Validation of IOP-SS Water Prediction using Loci-STREAM-VoF

    NASA Technical Reports Server (NTRS)

    Nielsen, Tanner; West, Jeff

    2015-01-01

    The Scale Model Acoustic Test (SMAT) is a 5% scale test of the Space Launch System (SLS), which is currently being designed at Marshall Space Flight Center (MSFC). SMAT consists of a 5% scale representation of the ignition overpressure sound-suppression system (IOP-SS) that is being tested to quantify the water flow and induced air entrainment in and around the mobile launcher exhaust hole. This data will be compared with computational fluid dynamics (CFD) simulations using the newly developed Loci-STREAM Volume of Fluid (VoF) methods. Compressible and incompressible VoF methods have been formulated, and are currently being used to simulate the water flow of SMAT IOP-SS. The test data will be used to qualitatively and quantitatively assess and validate the VoF methods.

  5. Acoustic Noise Test Report for the U.S. Department of Energy 1.5-Megawatt Wind Turbine

    SciTech Connect

    Roadman, Jason; Huskey, Arlinda

    2015-07-01

    A series of tests were conducted to characterize the baseline properties and performance of the U.S. Department of Energy (DOE) 1.5-megawatt wind turbine (DOE 1.5) to enable research model development and quantify the effects of future turbine research modifications. The DOE 1.5 is built on the platform of GE's 1.5-MW SLE commercial wind turbine model. It was installed in a nonstandard configuration at the NWTC with the objective of supporting DOE Wind Program research initiatives such as A2e. Therefore, the test results may not represent the performance capabilities of other GE 1.5-MW SLE turbines. The acoustic noise test documented in this report is one of a series of tests carried out to establish a performance baseline for the DOE 1.5 in the NWTC inflow environment.

  6. STS-70 Discovery launch startled birds at ignition

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Startled birds scatter as the stillness of a summer morning is broken by a giant's roar. The Space Shuttle Discovery thundered into space from launch Pad 39-B at 9:41:55:078 a.m. EDT. STS-70 is the 70th Shuttle flight overall, the 21st for Discovery (OV- 103), and the fourth Shuttle flight in 1995. On board for the nearly eight-day mission are a crew of five: Commander Terence 'Tom' Hendricks; Pilot Kevin R. Kregel; and Mission Specialists Nancy Jane Currie, Donald A. Thomas and Mary Ellen Weber. The crew's primary objective is to deploy the Tracking and Data Relay Satellite-G (TDRS-G), which will join a constellation of other TDRS spacecraft already on orbit.

  7. Discrete-Mode Source Development and Testing for New Seismo-Acoustic Sonar

    DTIC Science & Technology

    1998-03-01

    the English scientist, Lord Rayleigh (J.W. Strutt ) [Ref. 6] demonstrated theoretically that there exist waves that can propagate over the planar...and T.G. Muir, Aug. 1994. 6. Rayleigh , Lord (J.W. Strutt ), "On Waves Propagated along the Plane Surface of an Elastic Solid," Proceedings London...13. ABSTRACT (maximum 200 words) A seismo-acoustic sonar concept that uses guided interface waves ( Rayleigh or Schölte) is being developed to

  8. A Register of Underwater Acoustic Test Facilities in the United States, Canada, and the United Kingdom

    DTIC Science & Technology

    1993-04-01

    requirements. Mailing Address: Naval Surface Warfare Center Acoustic Research Detachment P.O. Box 129 Bayview, ID 83803-0129 Contact Person: George Guedel...needs. Mailing Address: Naval Surface Warfare Center , Crane Division Bldg 41NE Crane, IN 47522-5070 Contact Person: George T. Moody Tel (812) 854-4270...requirements. Mailing Address: Naval Undersea Warfare Center Detachment New London, CT 06320 Contact Person: Lynn Carlton Tel (203) 440-5811 Narrative

  9. Approach and withdrawal actions modulate the startle reflex independent of affective valence and muscular effort.

    PubMed

    Thibodeau, Ryan

    2011-07-01

    The startle reflex is modulated during processing of pleasant and unpleasant affective cues. One explanation of this finding contends that approach and withdrawal motivational processes are key to explaining the effect. Undergraduates performed arm flexion and arm extension actions shown elsewhere to reliably elicit approach and withdrawal motives, respectively. Results showed that arm extension (a withdrawal action) was associated with the largest startles, followed by a neutral control action and arm flexion (an approach action). This pattern was not attributable to the subjective pleasantness or muscular effort associated with the actions. Results support motivational priming accounts of startle reflex modulation.

  10. Testing and verification of a scale-model acoustic propagation system.

    PubMed

    Sagers, Jason D; Ballard, Megan S

    2015-12-01

    This paper discusses the design and operation of a measurement apparatus used to conduct scale-model underwater acoustic propagation experiments, presents experimental results for an idealized waveguide, and compares the measured results to data generated by two-dimensional (2D) and three-dimensional (3D) numerical models. The main objective of this paper is to demonstrate the capability of the apparatus for a simple waveguide that primarily exhibits 2D acoustic propagation. The apparatus contains a computer-controlled positioning system that accurately moves a receiving transducer in the water layer above a scale-model bathymetry while a stationary source transducer emits broadband pulsed waveforms. Experimental results are shown for a 2.133 m × 1.219 m bathymetric part possessing a flat-bottom bathymetry with a translationally invariant wedge of 10° slope along one edge. Beamformed results from a synthetic horizontal line array indicate the presence of strong in-plane arrivals along with weaker diffracted and horizontally refracted arrivals. A simulated annealing inversion method is applied to infer values for five waveguide parameters with the largest measurement uncertainty. The inferred values are then used in a 2D method of images model and a 3D adiabatic normal-mode model to simulate the measured acoustic data.

  11. A seismic field test with a Low-level Acoustic Combustion Source and Pseudo-Noise codes

    NASA Astrophysics Data System (ADS)

    Askeland, Bjørn; Ruud, Bent Ole; Hobæk, Halvor; Mjelde, Rolf

    2009-01-01

    The Low-level Acoustic Combustion Source (LACS) which can fire its pulses at a high rate, has been tested successfully as a seismic marine source on shallow ice-age sediments in Byfjorden at Bergen, Norway. Pseudo-Noise pulsed signals with spiky autocorrelation functions were used to detect the sediments. Each transmitted sequence lasted 10 s and contained 43 pulses. While correlation gave a blurry result, deconvolution between the near-field recordings and the streamer recordings gave a clear seismic section. Compared to the section acquired with single air-gun shots along the same profile, the LACS gave a more clear presentation of the sediments and basement.

  12. AST Launch Vehicle Acoustics

    NASA Technical Reports Server (NTRS)

    Houston, Janice; Counter, D.; Giacomoni, D.

    2015-01-01

    The liftoff phase induces acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are then used in the prediction of internal vibration responses of the vehicle and components which result in the qualification levels. Thus, predicting these liftoff acoustic (LOA) environments is critical to the design requirements of any launch vehicle. If there is a significant amount of uncertainty in the predictions or if acoustic mitigation options must be implemented, a subscale acoustic test is a feasible pre-launch test option to verify the LOA environments. The NASA Space Launch System (SLS) program initiated the Scale Model Acoustic Test (SMAT) to verify the predicted SLS LOA environments and to determine the acoustic reduction with an above deck water sound suppression system. The SMAT was conducted at Marshall Space Flight Center and the test article included a 5% scale SLS vehicle model, tower and Mobile Launcher. Acoustic and pressure data were measured by approximately 250 instruments. The SMAT liftoff acoustic results are presented, findings are discussed and a comparison is shown to the Ares I Scale Model Acoustic Test (ASMAT) results.

  13. Development of the Acoustically Evoked Behavioral Response in Larval Plainfin Midshipman Fish, Porichthys notatus

    PubMed Central

    Alderks, Peter W.; Sisneros, Joseph A.

    2013-01-01

    The ontogeny of hearing in fishes has become a major interest among bioacoustics researchers studying fish behavior and sensory ecology. Most fish begin to detect acoustic stimuli during the larval stage which can be important for navigation, predator avoidance and settlement, however relatively little is known about the hearing capabilities of larval fishes. We characterized the acoustically evoked behavioral response (AEBR) in the plainfin midshipman fish, Porichthys notatus, and used this innate startle-like response to characterize this species' auditory capability during larval development. Age and size of larval midshipman were highly correlated (r2 = 0.92). The AEBR was first observed in larvae at 1.4 cm TL. At a size ≥1.8 cm TL, all larvae responded to a broadband stimulus of 154 dB re1 µPa or −15.2 dB re 1 g (z-axis). Lowest AEBR thresholds were 140–150 dB re 1 µPa or −33 to −23 dB re 1 g for frequencies below 225 Hz. Larval fish with size ranges of 1.9–2.4 cm TL had significantly lower best evoked frequencies than the other tested size groups. We also investigated the development of the lateral line organ and its function in mediating the AEBR. The lateral line organ is likely involved in mediating the AEBR but not necessary to evoke the startle-like response. The midshipman auditory and lateral line systems are functional during early development when the larvae are in the nest and the auditory system appears to have similar tuning characteristics throughout all life history stages. PMID:24340003

  14. Challenging Pneumatic Requirements for Acoustic Testing of the Cryogenic Second Stage for the New Delta 3 Rocket

    NASA Technical Reports Server (NTRS)

    Webb, Andrew T.

    1998-01-01

    The paper describes the unique pneumatic test requirements for the acoustic and shock separation testing of the Second Stage for the new Delta III Rocket at the Goddard Space Flight Center in Greenbelt, Maryland. The testing was conducted in the 45,000 cu ft (25-feet wide by 30-feet deep by 50-foot high) Acoustic Facility. The acoustic testing required that the liquid oxygen (LOX) and liquid hydrogen (LH2) tanks be filled with enough liquid nitrogen (LN2) to simulate launch fuel masses during testing. The challenge for this test dealt with designing, procuring, and fabricating the pneumatic supply systems for quick assembly while maintaining the purity requirements and minimizing costs. The pneumatic systems were designed to fill and drain the both LOX and LH2 tanks as well as to operate the fill/drain and vent valves for each of the tanks. The test criteria for the pneumatic sub-systems consisted of function, cleanliness, availability, and cost. The first criteria, function, required the tanks to be filled and drained in an efficient manner while preventing them from seeing pressures greater than 9 psig which would add a pressure cycle to the tank. An LN2 tanker, borrowed from another NASA facility, served as the pre-cool and drain tanker. Pre-cooling the tanks allowed for more efficient and cost effective transfer from the LN2 delivery tankers. Helium gas, supplied from a high purity tube trailer, was used to pressurize the vapor space above the LN2 pushing it into the drain tanker. The tube trailer also supplied high pressure helium to the vehicle for valve control and component purges. Cleanliness was maintained by proper component selection, end-use particle filtration, and any on-site cleaning determined necessary by testing. In order to meet the availability/cost juggling act, products designed for LOX delivery systems were procured to ensure system compatibility while off the shelf valves and tubing designed for the semiconductor industry were procured for

  15. Go-activation endures following the presentation of a stop-signal: evidence from startle.

    PubMed

    Drummond, Neil M; Cressman, Erin K; Carlsen, Anthony N

    2017-01-01

    It has been proposed that, in a stop-signal task (SST), independent go- and stop-processes "race" to control behavior. If the go-process wins, an overt response is produced, whereas, if the stop-process wins, the response is withheld. One prediction that follows from this proposal is that, if the activation associated with one process is enhanced, it is more likely to win the race. We looked to determine whether these initiation and inhibition processes (and thus response outcomes) could be manipulated by using a startling acoustic stimulus (SAS), which has been shown to provide additional response activation. In the present study, participants were to respond to a visual go-stimulus; however, if a subsequent stop-signal appeared, they were to inhibit the response. The stop-signal was presented at a delay corresponding to a probability of responding of 0.4 (determined from a baseline block of trials). On stop-trials, a SAS was presented either simultaneously with the go-signal or stop-signal or 100, 150, or 200 ms following the stop-signal. Results showed that presenting a SAS during stop-trials led to an increase in probability of responding when presented with or following the stop-signal. The latency of SAS responses at the stop-signal + 150 ms and stop-signal + 200 ms probe times suggests that they would have been voluntarily inhibited but instead were involuntarily initiated by the SAS. Thus results demonstrate that go-activation endures even 200 ms following a stop-signal and remains accessible well after the response has been inhibited, providing evidence against a winner-take-all race between independent go- and stop-processes.

  16. In Vivo Ca(2+) Imaging Reveals that Decreased Dendritic Excitability Drives Startle Habituation.

    PubMed

    Marsden, Kurt C; Granato, Michael

    2015-12-01

    Exposure to repetitive startling stimuli induces habitation, a simple form of learning. Despite its simplicity, the precise cellular mechanisms by which repeated stimulation converts a robust behavioral response to behavioral indifference are unclear. Here, we use head-restrained zebrafish larvae to monitor subcellular Ca(2+) dynamics in Mauthner neurons, the startle command neurons, during startle habituation in vivo. Using the Ca(2+) reporter GCaMP6s, we find that the amplitude of Ca(2+) signals in the lateral dendrite of the Mauthner neuron determines startle probability and that depression of this dendritic activity rather than downstream inhibition mediates glycine and N-methyl-D-aspartate (NMDA)-receptor-dependent short-term habituation. Combined, our results suggest a model for habituation learning in which increased inhibitory drive from feedforward inhibitory neurons combined with decreased excitatory input from auditory afferents decreases dendritic and Mauthner neuron excitability.

  17. Use of Strain Measurements from Acoustic Bench Tests of the Battleship Flowliner Test Articles To Link Analytical Model Results to In-Service Resonant Response

    NASA Technical Reports Server (NTRS)

    Frady, Greg; Smaolloey, Kurt; LaVerde, Bruce; Bishop, Jim

    2004-01-01

    The paper will discuss practical and analytical findings of a test program conducted to assist engineers in determining which analytical strain fields are most appropriate to describe the crack initiating and crack propagating stresses in thin walled cylindrical hardware that serves as part of the Space Shuttle Main Engine's fuel system. In service the hardware is excited by fluctuating dynamic pressures in a cryogenic fuel that arise from turbulent flow/pump cavitation. A bench test using a simplified system was conducted using acoustic energy in air to excite the test articles. Strain measurements were used to reveal response characteristics of two Flowliner test articles that are assembled as a pair when installed in the engine feed system.

  18. Subpilot-scale testing of acoustically enhanced cyclone collectors. Final report, September 1988--September 1994

    SciTech Connect

    Galica, M.A.; Campbell, A.H.; Rawlins, D.C.

    1994-08-01

    Gas turbines are used to recover energy from high temperature exhaust gases in coal-fired pressurized-fluidized bed, combined-cycle power generation systems. However, prior to entering the turbine hot-section, the majority of the fly ash must be removed in order to protect the turbine components from erosion, corrosion, and deposition of the ash. The U.S. Department of Energy under the direction of the Morgantown Energy Technology Center (METC) sponsored the development of an acoustically enhanced cyclone collector which offers the potential of achieving environmental control standards under Pressurized Fluid Bed Combustors (PFBC) conditions without the need for post-turbine particulate control. Pulse combustors developed by Manufacturing and Technology Conversation International, Inc. (MTCI) produced the acoustic power necessary to agglomerate ash particles into sizes large enough to be collected in a conventional cyclone system. A hot gas cleanup system that meets both turbine protection and emissions requirements without post-turbine particulate controls would also have improved overall system economics.

  19. Heroin reduces startle and cortisol response in opioid-maintained heroin-dependent patients.

    PubMed

    Walter, Marc; Wiesbeck, Gerhard A; Degen, Bigna; Albrich, Jürgen; Oppel, Monika; Schulz, André; Schächinger, Hartmut; Dürsteler-MacFarland, Kenneth M

    2011-01-01

    Heroin dependence (HD) is a chronic relapsing brain disorder characterized by a compulsion to seek and use heroin. Stress is seen as a key factor for heroin use. Methadone maintenance and the prescription of pharmaceutical heroin [diacetylmorphine (DAM)] are established treatments for HD in several countries. The present study examined whether DAM-maintained patients and methadone-maintained patients differ from healthy controls in startle reflex and cortisol levels. Fifty-seven participants, 19 of each group matched for age, sex and smoking status, completed a startle session which included the presentation of 24 bursts of white noise while eye-blink responses to startling noises were recorded. Salivary cortisol was collected three times after awakening, before, during and after the startle session. DAM was administered before the experiment, while methadone was administered afterwards. Both heroin-dependent patient groups exhibited significantly smaller startle responses than healthy controls (P < 0.05). Whereas the cortisol levels after awakening did not differ across the three groups, the experimental cortisol levels were significantly lower in DAM-maintained patients, who received their opioid before the experiment, than in methadone-maintained patients and healthy controls (P < 0.0001). Opioid maintenance treatment for HD is associated with reduced startle responses. Acute DAM administration may suppress cortisol levels, and DAM maintenance treatment may represent an effective alternative to methadone in stress-sensitive, heroin-dependent patients.

  20. Affective startle potentiation in juvenile offenders: the role of conduct problems and psychopathic traits.

    PubMed

    Syngelaki, Eva M; Fairchild, Graeme; Moore, Simon C; Savage, Justin C; van Goozen, Stephanie H M

    2013-01-01

    Emotion processing difficulties are observed in antisocial individuals exhibiting serious antisocial behavior. This study examined emotion processing in 40 male juvenile offenders (JOs) and 52 male controls by measuring startle reflex responses to aversive sounds during the passive viewing of affective and neutral images. JOs as a group exhibited reduced startle-elicited blinks across all slide categories compared to normal controls. Moreover, within the offender group those with more conduct disorder symptoms and higher levels of psychopathic traits displayed reduced startle amplitudes compared to lower-scoring offenders. The finding that startle magnitudes were inversely related to severity of conduct problems supports a dimensional or continuous approach to understanding externalizing disorders. Reductions in amygdala activity could lead to blunted startle magnitudes. The current findings not only provide further evidence that antisocial children have a general defensive motivational system dysfunction and present with impairments in neural systems that subserve emotion processing, but also show for the first time that those with more severe conduct problems have reduced startle responses compared to those who are less severely affected. The implications of these findings for interventions with JOs are discussed.

  1. Acoustic Emission and Damage Accumulation for Various Woven C/SiC Composites Tested in Tension at Room Temperature

    NASA Technical Reports Server (NTRS)

    Morscher, Gregory; Petko, Jeanne; Kiser, James D.

    2002-01-01

    Modal acoustic emission (AE) has proven to be an excellent technique to monitor damage accumulation in ceramic matrix composites. In this study, AE was used to monitor tensile load-unload-reload hysteresis tests for a variety of C fiber reinforced, Sic matrix composites. C/SiC composites were reinforced with T-300 and IM7 fibers, had C, multilayer, or pseudo-porous C interphases, and had chemical vapor infiltrated Sic or melt-infiltrated SiC matrices. All of the composites exhibited considerable AE during testing. The extent and nature of the AE activity will be analyzed and discussed in light of matrix cracking and the variety of composite constituents. It is hoped that understanding the nature of stress-dependent damage accumulation in these materials can be of use in life-modeling for these types of composites.

  2. Acoustic Emission and Damage Accumulation for Various Woven C/SiC Composites Tested in Tension at Room Temperature

    NASA Technical Reports Server (NTRS)

    Morscher, Gregory N.; Petko, Jeanne; Kiser, James D.; Gray, Hugh R. (Technical Monitor)

    2002-01-01

    Modal acoustic emission (AE) has proven to be an excellent technique to monitor damage accumulation in ceramic matrix composites. In this study, AE was used to monitor tensile load-unload-reload hysteresis tests for a variety of C fiber reinforced, SiC matrix composites. C/SiC composites were reinforced with T300 and IM7 fibers, had C, multilayer, or pseudo-porous C interphases, and had chemical vapor infiltrated SiC or melt-infiltrated SiC matrices. All of the composites exhibited considerable AE during testing. The extent and nature of the AE activity will be analyzed and discussed in light of matrix cracking and the variety of composite constituents. It is hoped that understanding the nature of stress dependent damage accumulation in these materials can be of use in life modeling for these types of composites.

  3. Child Maltreatment, Callous-Unemotional Traits, and Defensive Responding In High-Risk Children: An Investigation of Emotion-Modulated Startle Response

    PubMed Central

    Dackis, Melissa N.; Rogosch, Fred A.; Cicchetti, Dante

    2015-01-01

    Child maltreatment is associated with disruptions in physiological arousal, emotion regulation, and defensive responses to cues of threat and distress, as well as increased risk for callous unemotional (CU) traits and externalizing behavior. Developmental models of callous unemotional (CU) traits have focused on biological and genetic risk factors that contribute to hypoarousal and antisocial behavior, but have focused less on environmental influences (Blair, 2004; Daversa, 2010; Hare, Frazell, & Cox, 1978; Krueger, 2000; Shirtcliff et al., 2009; Viding, Fontaine, & McCrory, 2012). The aim of the present investigation was to measure the independent and combined effects of child maltreatment and high CU trait on emotion-modulated startle (EMS) response in children. Participants consisted of 132 low-income maltreated (n = 60) and nonmaltreated (n = 72) children between 8–12 years old who attended a summer camp program. Acoustic startle response (ASR) was elicited in response to a 110-dB 50-ms probe while children viewed a slideshow of pleasant, neutral, and unpleasant IAPS images. Maltreatment status was assessed through examination of Department of Human Services records. CU traits were measured using counselor reports from the Inventory of Callous and Unemotional Traits (ICU; Frick, 2004), and conduct problems were measured using counselor and child self-report. We found no significant differences in emotion-modulated startle in the overall sample. However, significant differences in ASR by maltreatment status, maltreatment subtype, and level of CU traits were apparent. Results indicated differential physiological responses for maltreated and nonmaltreated children based on CU traits, including a pathway of hypoarousal for nonmaltreated/high CU children that differed markedly from a more normative physiological trajectory for maltreated/high CU children. Further, we found heightened ASR for emotionally and physically neglected children with high CU and elevated

  4. Child maltreatment, callous-unemotional traits, and defensive responding in high-risk children: An investigation of emotion-modulated startle response.

    PubMed

    Dackis, Melissa N; Rogosch, Fred A; Cicchetti, Dante

    2015-11-01

    Child maltreatment is associated with disruptions in physiological arousal, emotion regulation, and defensive responses to cues of threat and distress, as well as increased risk for callous unemotional (CU) traits and externalizing behavior. Developmental models of CU traits have focused on biological and genetic risk factors that contribute to hypoarousal and antisocial behavior, but have focused less on environmental influences (Blair, 2004; Daversa, 2010; Hare, Frazell, & Cox, 1978; Krueger, 2000; Shirtcliff et al., 2009; Viding, Fontaine, & McCrory, 2012). The aim of the present investigation was to measure the independent and combined effects of child maltreatment and high CU traits on emotion-modulated startle response in children. Participants consisted of 132 low-income maltreated (n = 60) and nonmaltreated (n = 72) children between 8 and 12 years old who attended a summer camp program. Acoustic startle response (ASR) was elicited in response to a 110-dB 50-ms probe while children viewed a slideshow of pleasant, neutral, and unpleasant IAPS images. Maltreatment status was assessed through examination of Department of Human Services records. CU traits were measured using counselor reports from the Inventory of Callous and Unemotional Traits (Frick, 2004), and conduct problems were measured using counselor and child self-report. We found no significant differences in emotion-modulated startle in the overall sample. However, significant differences in ASR by maltreatment status, maltreatment subtype, and level of CU traits were apparent. Results indicated differential physiological responses for maltreated and nonmaltreated children based on CU traits, including a pathway of hypoarousal for nonmaltreated/high CU children that differed markedly from a more normative physiological trajectory for maltreated/high CU children. Further, we found heightened ASR for emotionally and physically neglected children with high CU and elevated antisocial behavior in these

  5. Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis.

    PubMed

    Heekeren, K; Neukirch, A; Daumann, J; Stoll, M; Obradovic, M; Kovar, K-A; Geyer, M A; Gouzoulis-Mayfrank, E

    2007-05-01

    Patients with schizophrenia exhibit diminished prepulse inhibition (PPI) of the acoustic startle reflex and deficits in the attentional modulation of PPI. Pharmacological challenges with hallucinogens are used as models for psychosis in both humans and animals. Remarkably, in contrast to the findings in schizophrenic patients and in animal hallucinogen models of psychosis, previous studies with healthy volunteers demonstrated increased levels of PPI after administration of low to moderate doses of either the antiglutamatergic hallucinogen ketamine or the serotonergic hallucinogen psilocybin. The aim of the present study was to investigate the influence of moderate and high doses of the serotonergic hallucinogen N,N-dimethyltryptamine (DMT) and the N-methyl-D-aspartate antagonist S-ketamine on PPI and its attentional modulation in humans. Fifteen healthy volunteers were included in a double-blind cross-over study with two doses of DMT and S-ketamine. Effects on PPI and its attentional modulation were investigated. Nine subjects completed both experimental days with the two doses of both drugs. S-ketamine increased PPI in both dosages, whereas DMT had no significant effects on PPI. S-ketamine decreased and DMT tended to decrease startle magnitude. There were no significant effects of either drug on the attentional modulation of PPI. In human experimental hallucinogen psychoses, and even with high, clearly psychotogenic doses of DMT or S-ketamine, healthy subjects failed to exhibit the predicted attenuation of PPI. In contrast, PPI was augmented and the startle magnitude was decreased after S-ketamine. These data point to important differences between human hallucinogen models and both animal hallucinogen models of psychosis and naturally occurring schizophrenia.

  6. Advantages of laser-acoustical leak testing for construction and operation of low-temperature installations and superconducting experiments

    NASA Astrophysics Data System (ADS)

    Herz, W.

    2002-09-01

    At the Institute of Technical Physics of the Research Center Karlsruhe, superconducting magnets for nuclear fusion applications have been tested in the vacuum tank TOSKA for more than 20 years. A crucial test parameter of the magnet coils (mass up to 120 metric tons) as well as of the peripheral components, such as current leads (up to 80 kA), helium refrigerators (2 kW), and low-temperature transfer lines (length approx200 m), is their vacuum tightness at operating conditions (minimum temperature approx2 K, maximum refrigerant pressure 25 bar). Because the final tests at cryotemperature are costly and time consuming, intermediate tests at room temperature have already been performed at the stages of manufacturing, certification, and assembling, and prior to cooldown. So far, these tightness tests have been performed with probe gas helium employing a conventional mass spectrometer leak detector, whereby the smallest detectable leakage is limited by the He partial pressure in the surrounding air. Therefore, a new technique of leak measurement was investigated using the probe gas sulfur hexafluoride SF6, which does not occur in natural air, and which can be sensitively detected by a laser-acoustical leak detector. The obtained experimental results reveal the substantial advantages of the new method with respect to detection sensitivity, testing expenditure, and costs. The results can be transferred to tightness tests in other fields of technology. copyright 2002 American Vacuum Society.

  7. Flight and Static Exhaust Flow Properties of an F110-GE-129 Engine in an F-16XL Airplane During Acoustic Tests

    NASA Technical Reports Server (NTRS)

    Holzman, Jon K.; Webb, Lannie D.; Burcham, Frank W., Jr.

    1996-01-01

    The exhaust flow properties (mass flow, pressure, temperature, velocity, and Mach number) of the F110-GE-129 engine in an F-16XL airplane were determined from a series of flight tests flown at NASA Dryden Flight Research Center, Edwards, California. These tests were performed in conjunction with NASA Langley Research Center, Hampton, Virginia (LARC) as part of a study to investigate the acoustic characteristics of jet engines operating at high nozzle pressure conditions. The range of interest for both objectives was from Mach 0.3 to Mach 0.9. NASA Dryden flew the airplane and acquired and analyzed the engine data to determine the exhaust characteristics. NASA Langley collected the flyover acoustic measurements and correlated these results with their current predictive codes. This paper describes the airplane, tests, and methods used to determine the exhaust flow properties and presents the exhaust flow properties. No acoustics results are presented.

  8. Numerical inverse method predicting acoustic spinning modes radiated by a ducted fan from free-field test data.

    PubMed

    Lewy, Serge

    2008-07-01

    Spinning modes generated by a ducted turbofan at a given frequency determine the acoustic free-field directivity. An inverse method starting from measured directivity patterns is interesting in providing information on the noise sources without requiring tedious spinning-mode experimental analyses. According to a previous article, equations are based on analytical modal splitting inside a cylindrical duct and on a Rayleigh or a Kirchhoff integral on the duct exit cross section to get far-field directivity. Equations are equal in number to free-field measurement locations and the unknowns are the propagating mode amplitudes (there are generally more unknowns than equations). A MATLAB procedure has been implemented by using either the pseudoinverse function or the backslash operator. A constraint comes from the fact that squared modal amplitudes must be positive which involves an iterative least squares fitting. Numerical simulations are discussed along with several examples based on tests performed by Rolls-Royce in the framework of a European project. It is assessed that computation is very fast and it well fits the measured directivities, but the solution depends on the method and is not unique. This means that the initial set of modes should be chosen according to any known physical property of the acoustic sources.

  9. Methodological considerations of acoustic playbacks to test the behavioral significance of call directionality in male northern elephant seals (Mirounga angustirostris)

    NASA Astrophysics Data System (ADS)

    Holt, Marla M.; Insley, Stephen J.; Southall, Brandon L.; Schusterman, Ronald J.

    2005-09-01

    While attempting to gain access to receptive females, male northern elephant seals form dominance hierarchies through multiple dyadic interactions involving visual and acoustic signals. These signals are both highly stereotyped and directional. Previous behavioral observations suggested that males attend to the directional cues of these signals. We used in situ vocal playbacks to test whether males attend to directional cues of the acoustic components of a competitors calls (i.e., variation in call spectra and source levels). Here, we will focus on playback methodology. Playback calls were multiple exemplars of a marked dominant male from an isolated area, recorded with a directional microphone and DAT recorder and edited into a natural sequence that controlled call amplitude. Control calls were recordings of ambient rookery sounds with the male calls removed. Subjects were 20 marked males (10 adults and 10 subadults) all located at An~o Nuevo, CA. Playback presentations, calibrated for sound-pressure level, were broadcast at a distance of 7 m from each subject. Most responses were classified into the following categories: visual orientation, postural change, calling, movement toward or away from the loudspeaker, and re-directed aggression. We also investigated developmental, hierarchical, and ambient noise variables that were thought to influence male behavior.

  10. Affective reactions to acoustic stimuli.

    PubMed

    Bradley, M M; Lang, P J

    2000-03-01

    Emotional reactions to naturally occurring sounds (e.g., screams, erotica, bombs, etc.) were investigated in two studies. In Experiment 1, subjects rated the pleasure and arousal elicited when listening to each of 60 sounds, followed by an incidental free recall task. The shape of the two-dimensional affective space defined by the mean ratings for each sound was similar to that previously obtained for pictures, and, like memory for pictures, free recall was highest for emotionally arousing stimuli. In Experiment 2, autonomic and facial electromyographic (EMG) activity were recorded while a new group of subjects listened to the same set of sounds; the startle reflex was measured using visual probes. Listening to unpleasant sounds resulted in larger startle reflexes, more corrugator EMG activity, and larger heart rate deceleration compared with listening to pleasant sounds. Electrodermal reactions were larger for emotionally arousing than for neutral materials. Taken together, the data suggest that acoustic cues activate the appetitive and defensive motivational circuits underlying emotional expression in ways similar to pictures.

  11. The design and flight test of an engine inlet bulk acoustic liner

    NASA Technical Reports Server (NTRS)

    Lester, H. C.; Preisser, J. S.; Parrott, T. L.

    1983-01-01

    This paper summarizes the design, fabrication and flight evaluation of a Kevlar acoustic liner configuration for a JT15D turbofan engine. The liner was designed to suppress, by a measurable amount, a dominant (13,0) BPF tone. This tone or spinning mode was produced for research purposes by installing 41 circumferentially distributed small diameter rods upstream of the 28 fan blades. Duct liner attenuations calculated by a finite element procedure were compared to far field power (insertion) losses deduced from flight data. The finite element program modeled the variable geometry of the JT15D inlet and used a uniform flow with a boundary layer roll-off to model the inlet flow field. Calculated liner losses were generally conservative. That is, measured far field power losses were generally greater than attenuations calculated by the finite element computer program.

  12. AX+, BX- Discrimination Learning in the Fear-Potentiated Startle Paradigm: Possible Relevance to Inhibitory Fear Learning in Extinction

    PubMed Central

    Myers, Karyn M.; Davis, Michael

    2004-01-01

    The neural mechanisms of fear suppression most commonly are studied through the use of extinction, a behavioral procedure in which a feared stimulus (i.e., one previously paired with shock) is nonreinforced repeatedly, leading to a reduction or elimination of the fear response. Although extinction is perhaps the most convenient index of fear inhibition, a great deal of behavioral work suggests that postextinction training conditioned stimuli are both excitatory and inhibitory, making it difficult to determine whether a neural manipulation affects inhibition, excitation, or some combination thereof. For this reason we sought to develop a behavioral procedure that would render a stimulus primarily inhibitory while at the same time avoiding some of the issues raised by the traditional conditioned inhibition paradigm, namely second-order conditioning, external inhibition, and configural learning. Using the fear-potentiated startle paradigm, we adapted an AX+, BX- training procedure in which stimuli A and X were presented simultaneously and paired with shock, and stimuli B and X were presented simultaneously in the absence of shock. In testing, high levels of fear-potentiated startle were seen in the presence of A and AX and much lower levels were seen in the presence of B and AB, as would be predicted if stimulus B were a conditioned inhibitor. We believe this method is a viable alternative to the traditional conditioned inhibition training procedure and will be useful for studying the neural mechanisms of fear inhibition. PMID:15254216

  13. DEVELOPMENTAL THYROID HORMONE INSUFFICIENCY ALTERS THE AMPLITUDE OF THE ACOUSTIC STARTLE RESPONSE IN RATS

    EPA Science Inventory

    Purpose: The thyroid hormone (TH) system is one of the targets of endocrine disrupting chemicals. Since TH is essential for proper brain development, disruption by exposure to chemicals during development can result in adverse neurological outcomes. Previous studies revealed th...

  14. Stuttering in Adults: The Acoustic Startle Response, Temperamental Traits, and Biological Factors

    ERIC Educational Resources Information Center

    Alm, Per A.; Risberg, Jarl

    2007-01-01

    The purpose of this study was to investigate the relation between stuttering and a range of variables of possible relevance, with the main focus on neuromuscular reactivity, and anxiety. The explorative analysis also included temperament, biochemical variables, heredity, preonset lesions, and altered auditory feedback (AAF). An increased level of…

  15. Models and mechanisms of anxiety: evidence from startle studies

    PubMed Central

    Grillon, Christian

    2009-01-01

    Rationale Preclinical data indicates that threat stimuli elicit two classes of defensive behaviors, those that are associated with imminent danger and are characterized by avoidance or fight (fear), and those that are associated with temporally uncertain danger and are characterized by sustained apprehension and hypervigilance (anxiety). Objective To 1) review evidence for a distinction between fear and anxiety in animal and human experimental models using the startle reflex as an operational measure of aversive states, 2) describe experimental models of anxiety, as opposed to fear, in humans, 3) examine the relevance of these models to clinical anxiety. Results The distinction between phasic fear to imminent threat and sustained anxiety to temporally uncertain danger is suggested by psychopharmacological and behavioral evidence from ethological studies and can be traced back to distinct neuroanatomical systems, the amygdala and the bed nucleus of the stria terminalis. Experimental models of anxiety, not fear, are relevant to non-phobic anxiety disorders. Conclusions Progress in our understanding of normal and abnormal anxiety is critically dependent on our ability to model sustained aversive states to temporally uncertain threat. PMID:18058089

  16. Physiological reactivity of pregnant women to evoked fetal startle

    PubMed Central

    DiPietro, Janet A.; Voegtline, Kristin M.; Costigan, Kathleen A.; Aguirre, Frank; Kivlighan, Katie; Chen, Ping

    2013-01-01

    Objective The bidirectional nature of mother-child interaction is widely acknowledged during infancy and childhood. Prevailing models during pregnancy focus on unidirectional influences exerted by the pregnant woman on the developing fetus. Prior work has indicated that the fetus also affects the pregnant woman. Our objective was to determine whether a maternal psychophysiological response to stimulation of the fetus could be isolated. Methods Using a longitudinal design, an airborne auditory stimulus was used to elicit a fetal heart rate and motor response at 24 (n = 47) and 36 weeks (n = 45) gestation. Women were blind to condition (stimulus versus sham). Maternal parameters included cardiac (heart rate) and electrodermal (skin conductance) responses. Multilevel modeling of repeated measures with 5 data points per second was used to examine fetal and maternal responses. Results As expected, compared to a sham condition, the stimulus generated a fetal motor response at both gestational ages, consistent with a mild fetal startle. Fetal stimulation was associated with significant, transient slowing of maternal heart rate coupled with increased skin conductance within 10 s of the stimulus at both gestational ages. Nulliparous women showed greater electrodermal responsiveness. The magnitude of the fetal motor response significantly corresponded to the maternal skin conductance response at 5, 10, 15, and 30 s following stimulation. Conclusion Elicited fetal movement exerts an independent influence on the maternal autonomic nervous system. This finding contributes to current models of the dyadic relationship during pregnancy between fetus and pregnant woman. PMID:24119937

  17. Acoustic Neuroma

    MedlinePlus

    ... search IRSA's site Unique Hits since January 2003 Acoustic Neuroma Click Here for Acoustic Neuroma Practice Guideline ... to microsurgery. One doctor's story of having an acoustic neuroma In August 1991, Dr. Thomas F. Morgan ...

  18. Oxytocin and Social Support as Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats

    DTIC Science & Technology

    2011-05-01

    Oxytocin and Social Support as Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats Dr. Jeff Rosen University of...potentiated startle after 3 weeks of social isolation have been difficult to replicate. We suggest oxytocin is promising as a drug with novel...benefits for patients with PTSD. fear; anxiety; PTSD; startle; social isolation 60 jrosen@udel.edu Table of Contents

  19. Oxytocin and Social Support as Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats

    DTIC Science & Technology

    2009-09-01

    startle amplitude. They then received Pavlovian fear conditioning of five pairings of a 3 s light co-terminating with a 500 ms, 0.6mA footshock. Four...Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats PRINCIPAL INVESTIGATOR: Jeffrey B. Rosen, Ph.D...NUMBER Oxytocin and Social Support as Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats 5b. GRANT

  20. Results of Aero/Acoustic Tests and Analytical Studies of a Two-Dimensional Eight-Lobe Mixer-Ejector Exhaust Nozzle at Takeoff Conditions

    NASA Technical Reports Server (NTRS)

    Harrington, Douglas (Technical Monitor); Schweiger, P.; Stern, A.; Gamble, E.; Barber, T.; Chiappetta, L.; LaBarre, R.; Salikuddin, M.; Shin, H.; Majjigi, R.

    2005-01-01

    Hot flow aero-acoustic tests were conducted with Pratt & Whitney's High-Speed Civil Transport (HSCT) Mixer-Ejector Exhaust Nozzles by General Electric Aircraft Engines (GEAE) in the GEAE Anechoic Freejet Noise Facility (Cell 41) located in Evendale, Ohio. The tests evaluated the impact of various geometric and design parameters on the noise generated by a two-dimensional (2-D) shrouded, 8-lobed, mixer-ejector exhaust nozzle. The shrouded mixer-ejector provides noise suppression by mixing relatively low energy ambient air with the hot, high-speed primary exhaust jet. Additional attenuation was obtained by lining the shroud internal walls with acoustic panels, which absorb acoustic energy generated during the mixing process. Two mixer designs were investigated, the high mixing "vortical" and aligned flow "axial", along with variations in the shroud internal mixing area ratios and shroud length. The shrouds were tested as hardwall or lined with acoustic panels packed with a bulk absorber. A total of 21 model configurations at 1:11.47 scale were tested. The models were tested over a range of primary nozzle pressure ratios and primary exhaust temperatures representative of typical HSCT aero thermodynamic cycles. Static as well as flight simulated data were acquired during testing. A round convergent unshrouded nozzle was tested to provide an acoustic baseline for comparison to the test configurations. Comparisons were made to previous test results obtained with this hardware at NASA Glenn's 9- by 15-foot low-speed wind tunnel (LSWT). Laser velocimetry was used to investigate external as well as ejector internal velocity profiles for comparison to computational predictions. Ejector interior wall static pressure data were also obtained. A significant reduction in exhaust system noise was demonstrated with the 2-D shrouded nozzle designs.

  1. Target spectrum matrix definition for multiple-input- multiple-output control strategies applied on direct-field- acoustic-excitation tests

    NASA Astrophysics Data System (ADS)

    Alvarez Blanco, M.; Janssens, K.; Bianciardi, F.

    2016-09-01

    During the last two decades there have been several improvements on environmental acoustic qualification testing for launch and space vehicles. Direct field excitation (DFAX) tests using Multiple-Input-Multiple-Output (MIMO) control strategies seems to become the most cost-efficient way for component and subsystem acoustic testing. However there are still some concerns about the uniformity and diffusivity of the acoustic field produced by direct field testing. Lately, much of the documented progresses aimed to solve the non-uniformity of the field by altering the sound pressure level requirement, limiting responses and adding or modifying control microphones positions. However, the first two solutions imply modifying the qualification criteria, which could lead to under-testing, potentially risking the mission. Furthermore, adding or moving control microphones prematurely changes the system configuration, even if it is an optimal geometric layout in terms of wave interference patterns control. This research investigates the target definition as an initial condition for the acoustic MIMO control. Through experiments it is shown that for a given system configuration the performance of a DFAX test strongly depends on the target definition procedure. As output of this research a set of descriptors are presented describing a phenomenon defined as “Energy- sink”.

  2. Empirically based comparisons of the reliability and validity of common quantification approaches for eyeblink startle potentiation in humans.

    PubMed

    Bradford, Daniel E; Starr, Mark J; Shackman, Alexander J; Curtin, John J

    2015-12-01

    Startle potentiation is a well-validated translational measure of negative affect. Startle potentiation is widely used in clinical and affective science, and there are multiple approaches for its quantification. The three most commonly used approaches quantify startle potentiation as the increase in startle response from a neutral to threat condition based on (1) raw potentiation, (2) standardized potentiation, or (3) percent-change potentiation. These three quantification approaches may yield qualitatively different conclusions about effects of independent variables (IVs) on affect when within- or between-group differences exist for startle response in the neutral condition. Accordingly, we directly compared these quantification approaches in a shock-threat task using four IVs known to influence startle response in the no-threat condition: probe intensity, time (i.e., habituation), alcohol administration, and individual differences in general startle reactivity measured at baseline. We confirmed the expected effects of time, alcohol, and general startle reactivity on affect using self-reported fear/anxiety as a criterion. The percent-change approach displayed apparent artifact across all four IVs, which raises substantial concerns about its validity. Both raw and standardized potentiation approaches were stable across probe intensity and time, which supports their validity. However, only raw potentiation displayed effects that were consistent with a priori specifications and/or the self-report criterion for the effects of alcohol and general startle reactivity. Supplemental analyses of reliability and validity for each approach provided additional evidence in support of raw potentiation.

  3. Noninvasive Ultrasound Imaging for Bone Quality Assessment Using Scanning Confocal Acoustic Diagnosis, μCT, DXA Measurements, and Mechanical Testing

    NASA Astrophysics Data System (ADS)

    Qin, Yi-Xian; Xia, Yi; Lin, Wei; Mittra, Erik; Rubin, Clint; Gruber, Barry

    Osteoporosis is a disease characterized by decreased bone mass and progressive deterioration of the microstructure, affecting both mineral density and bone's fragility. Current diagnoses are only measuring apparent bone mineral density (AppBMD). Using our newly developed scanning confocal acoustic diagnostic (SCAD) system, we evaluated the ability of quantitative ultrasound in noninvasively predicting bone's quantity and quality on 19 human cadaver calcanei. Results show that ultrasound attenuation image on intact calcaneus represents bone mass distribution. High correlation (R=0.82) exists between SCAD determined broadband ultrasound attenuation (BUA) and DXA determined AppBMD at the calcaneus, as well as in the AppBMD result at femoral neck (R=0.81). SCAD determined BUA and ultrasound velocity (UV) are highly correlated with the micro-CT and mechanical testing determined bone quantity and quality parameters. These results suggest that image-based quantitative ultrasound is able to identify ROI and predict both bone mass and strength.

  4. Intolerance of uncertainty and startle potentiation in relation to different threat reinforcement rates.

    PubMed

    Chin, Brian; Nelson, Brady D; Jackson, Felicia; Hajcak, Greg

    2016-01-01

    Fear conditioning research on threat predictability has primarily examined the impact of temporal (i.e., timing) predictability on the startle reflex. However, there are other key features of threat that can vary in predictability. For example, the reinforcement rate (i.e., frequency) of threat is a crucial factor underlying fear learning. The present study examined the impact of threat reinforcement rate on the startle reflex and self-reported anxiety during a fear conditioning paradigm. Forty-five participants completed a fear learning task in which the conditioned stimulus was reinforced with an electric shock to the forearm on 50% of trials in one block and 75% of trials in a second block, in counter-balanced order. The present study also examined whether intolerance of uncertainty (IU), the tendency to perceive or experience uncertainty as stressful or unpleasant, was associated with the startle reflex during conditions of low (50%) vs. high (75%) reinforcement. Results indicated that, across all participants, startle was greater during the 75% relative to the 50% reinforcement condition. IU was positively correlated with startle potentiation (i.e., increased startle response to the CS+ relative to the CS-) during the 50%, but not the 75%, reinforcement condition. Thus, despite receiving fewer electric shocks during the 50% reinforcement condition, individuals with high IU uniquely demonstrated greater defense system activation when impending threat was more uncertain. The association between IU and startle was independent of state anxiety. The present study adds to a growing literature on threat predictability and aversive responding, and suggests IU is associated with abnormal responding in the context of uncertain threat.

  5. Modification of the Ames 40- by 80-foot wind tunnel for component acoustic testing for the second generation supersonic transport

    NASA Technical Reports Server (NTRS)

    Schmitz, F. H.; Allmen, J. R.; Soderman, P. T.

    1994-01-01

    The development of a large-scale anechoic test facility where large models of engine/airframe/high-lift systems can be tested for both improved noise reduction and minimum performance degradation is described. The facility development is part of the effort to investigate economically viable methods of reducing second generation high speed civil transport noise during takeoff and climb-out that is now under way in the United States. This new capability will be achieved through acoustic modifications of NASA's second largest subsonic wind tunnel: the 40-by 80-Foot Wind Tunnel at the NASA Ames Research Center. Three major items are addressed in the design of this large anechoic and quiet wind tunnel: a new deep (42 inch (107 cm)) test section liner, expansion of the wind tunnel drive operating envelope at low rpm to reduce background noise, and other promising methods of improving signal-to-noise levels of inflow microphones. Current testing plans supporting the U.S. high speed civil transport program are also outlined.

  6. Evidence for Startle Effects due to Externally Induced Lower Limb Movements: Implications in Neurorehabilitation

    PubMed Central

    Mayr, Andreas; Saltuari, Leopold

    2017-01-01

    Passive limb displacement is routinely used to assess muscle tone. If we attempt to quantify muscle stiffness using mechanical devices, it is important to know whether kinematic stimuli are able to trigger startle reactions. Whether kinematic stimuli are able to elicit a startle reflex and to accelerate prepared voluntary movements (StartReact effect) has not been studied extensively to date. Eleven healthy subjects were suspended in an exoskeleton and were exposed to passive left knee flexion (KF) at three intensities, occasionally replaced by fast right KF. Upon perceiving the movement subjects were asked to perform right wrist extension (WE), assessed by extensor carpi radialis (ECR) electromyographic activity. ECR latencies were shortest in fast trials. Startle responses were present in most fast trials, yet being significantly accelerated and larger with right versus left KF, since the former occurred less frequently and thus less expectedly. Startle responses were associated with earlier and larger ECR responses (StartReact effect), with the largest effect again upon right KF. The results provide evidence that kinematic stimuli are able to elicit both startle reflexes and a StartReact effect, which depend on stimulus intensity and anticipation, as well as on the subjects' preparedness to respond. PMID:28299334

  7. Thermal Imaging of the Periorbital Regions during the Presentation of an Auditory Startle Stimulus

    PubMed Central

    Gane, Luke; Power, Sarah; Kushki, Azadeh; Chau, Tom

    2011-01-01

    Infrared thermal imaging of the inner canthi of the periorbital regions of the face can potentially serve as an input signal modality for an alternative access system for individuals with conditions that preclude speech or voluntary movement, such as total locked-in syndrome. However, it is unknown if the temperature of these regions is affected by the human startle response, as changes in the facial temperature of the periorbital regions manifested during the startle response could generate false positives in a thermography-based access system. This study presents an examination of the temperature characteristics of the periorbital regions of 11 able-bodied adult participants before and after a 102 dB auditory startle stimulus. The results indicate that the startle response has no substantial effect on the mean temperature of the periorbital regions. This indicates that thermography-based access solutions would be insensitive to startle reactions in their user, an important advantage over other modalities being considered in the context of access solutions for individuals with a severe motor disability. PMID:22073302

  8. The effects of an auditory startle on obstacle avoidance during walking

    PubMed Central

    Queralt, Ana; Weerdesteyn, Vivian; van Duijnhoven, Hanneke J R; Castellote, Juan M; Valls-Solé, Josep; Duysens, Jacques

    2008-01-01

    Movement execution is speeded up when a startle auditory stimulus is applied with an imperative signal in a simple reaction time task experiment, a phenomenon described as StartReact. The effect has been recently observed in a step adjustment task requiring fast selection of specific movements in a choice reaction time task. Therefore, we hypothesized that inducing a StartReact effect may be beneficial in obstacle avoidance under time pressure, when subjects have to perform fast gait adjustments. Twelve healthy young adults walked on a treadmill and obstacles were released in specific moments of the step cycle. On average the EMG onset latency in the biceps femoris shortened by 20% while amplitude increased by 50%, in trials in which an auditory startle accompanied obstacle avoidance. The presentation of a startle increased the probability of using a long step strategy, enlarged stride length modifications and resulted in higher success rates, to avoid the obstacle. We also examined the effects of the startle in a condition in which the obstacle was not present in comparison to a condition in which the obstacle was visibly present but it did not fall. In the latter condition, the obstacle avoidance reaction occurred with a similar latency but smaller amplitude as in trials in which the obstacle was actually released. Our results suggest that the motor programmes used for obstacle avoidance are probably stored at subcortical structures. The release of these motor programmes by a startling auditory stimulus may combine intersensory facilitation and the StartReact effect. PMID:18653659

  9. Depletion of serotonin in the basolateral amygdala elevates glutamate receptors and facilitates fear-potentiated startle

    PubMed Central

    Tran, L; Lasher, B K; Young, K A; Keele, N B

    2013-01-01

    Our previous experiments demonstrated that systemic depletion of serotonin (5-hydroxytryptamine, 5-HT), similar to levels reported in patients with emotional disorders, enhanced glutamateric activity in the lateral nucleus of the amygdala (LA) and potentiated fear behaviors. However, the effects of isolated depletion of 5-HT in the LA, and the molecular mechanisms underlying enhanced glutamatergic activity are unknown. In the present study, we tested the hypothesis that depletion of 5-HT in the LA induces increased fear behavior, and concomitantly enhances glutamate receptor (GluR) expression. Bilateral infusions of 5,7-dihydroxytryptamine (4 μg per side) into the LA produced a regional reduction of serotonergic fibers, resulting in decreased 5-HT concentrations. The induction of low 5-HT in the LA elevated fear-potentiated startle, with a parallel increase in GluR1 mRNA and GluR1 protein expression. These findings suggest that low 5-HT concentrations in the LA may facilitate fear behavior through enhanced GluR-mediated mechanisms. Moreover, our data support a relationship between 5-HT and glutamate in psychopathologies. PMID:24002084

  10. Acoustic sensor engineering evaluation test report. [microphones for monitoring inside the space shuttle orbiter

    NASA Technical Reports Server (NTRS)

    Phillips, E. L., Jr.; Bronson, R. D.

    1976-01-01

    Two types of one-inch diameter sound pressure level sensors, which are candidates for monitoring ambient noise in the shuttle orbiter crew compartment during rest periods, were exposed to temperature, passive humidity, and vibration. One unexposed sensor of each type served as a reference unit. Except for the humidity exposures, each of the three capacitive microphones was individually tested in sequence with the essential voltage power supply and preamplifier. One unit exibited anomalous characteristics after the humidity exposure but returned to normal after being dried in an oven at 115 deg for two hours. Except for the humidity exposures, each of the three piezoelectric microphones was individually tested with a laboratory type amplifier. Two apparent failures occurred during these tests. The diaphragm on one was found ruptured after the fourth cycle of the humidity test. A second sensor showed an anomaly after the random vibration tests at which time its sensitivity was consistent at about one-half its former value.

  11. Fear conditioning of SCR but not the startle reflex requires conscious discrimination of threat and safety.

    PubMed

    Sevenster, Dieuwke; Beckers, Tom; Kindt, Merel

    2014-01-01

    There is conflicting evidence as to whether awareness is required for conditioning of the skin conductance response (SCR). Recently, Schultz and Helmstetter (2010) reported SCR conditioning in contingency unaware participants by using difficult to discriminate stimuli. These findings are in stark contrast with other observations in human fear conditioning research, showing that SCR predominantly reflects contingency learning. Therefore, we repeated the study by Schultz and Helmstetter and additionally measured conditioning of the startle response, which seems to be less sensitive to declarative knowledge than SCR. While we solely observed SCR conditioning in participants who reported awareness of the contingencies (n = 16) and not in the unaware participants (n = 18), we observed startle conditioning irrespective of awareness. We conclude that SCR but not startle conditioning depends on conscious discriminative fear learning.

  12. In Your Face: Startle to Emotional Facial Expressions Depends on Face Direction

    PubMed Central

    Michalsen, Henriette; Øvervoll, Morten

    2017-01-01

    Although faces are often included in the broad category of emotional visual stimuli, the affective impact of different facial expressions is not well documented. The present experiment investigated startle electromyographic responses to pictures of neutral, happy, angry, and fearful facial expressions, with a frontal face direction (directed) and at a 45° angle to the left (averted). Results showed that emotional facial expressions interact with face direction to produce startle potentiation: Greater responses were found for angry expressions, compared with fear and neutrality, with directed faces. When faces were averted, fear and neutrality produced larger responses compared with anger and happiness. These results are in line with the notion that startle is potentiated to stimuli signaling threat. That is, a forward directed angry face may signal a threat toward the observer, and a fearful face directed to the side may signal a possible threat in the environment. PMID:28321290

  13. Toward an understanding of the emotion-modulated startle eyeblink reflex: the case of anger.

    PubMed

    Peterson, Carly K; Harmon-Jones, Eddie

    2012-11-01

    Three studies investigated the effect of angering pictures on the startle eyeblink response, based on anger's unique identity as an approach-oriented negative affect. In Study 1, eyeblinks to startling noise probes during angering and neutral pictures did not differ, despite angering pictures being rated higher on arousal and anger and more negative in valence. Study 2 replicated Study 1; also, dysphoric participants exhibited potentiated eyeblinks to probes during angering pictures much like those to probes during fear/disgust stimuli. A follow-up study revealed that dysphoric participants rated angering pictures higher in fear. Study 3 again found that eyeblinks to probes during angering and neutral pictures did not differ. Taken together, these results suggest that probes during angering stimuli elicit eyeblinks much like those during neutral stimuli, perhaps due to the competing influences of arousal, valence, and motivation on the startle eyeblink reflex.

  14. The time course of face processing: startle eyeblink response modulation by face gender and expression.

    PubMed

    Duval, Elizabeth R; Lovelace, Christopher T; Aarant, Justin; Filion, Diane L

    2013-12-01

    The purpose of this study was to investigate the effects of both facial expression and face gender on startle eyeblink response patterns at varying lead intervals (300, 800, and 3500ms) indicative of attentional and emotional processes. We aimed to determine whether responses to affective faces map onto the Defense Cascade Model (Lang et al., 1997) to better understand the stages of processing during affective face viewing. At 300ms, there was an interaction between face expression and face gender with female happy and neutral faces and male angry faces producing inhibited startle. At 3500ms, there was a trend for facilitated startle during angry compared to neutral faces. These findings suggest that affective expressions are perceived differently in male and female faces, especially at short lead intervals. Future studies investigating face processing should take both face gender and expression into account.

  15. In Your Face: Startle to Emotional Facial Expressions Depends on Face Direction.

    PubMed

    Åsli, Ole; Michalsen, Henriette; Øvervoll, Morten

    2017-01-01

    Although faces are often included in the broad category of emotional visual stimuli, the affective impact of different facial expressions is not well documented. The present experiment investigated startle electromyographic responses to pictures of neutral, happy, angry, and fearful facial expressions, with a frontal face direction (directed) and at a 45° angle to the left (averted). Results showed that emotional facial expressions interact with face direction to produce startle potentiation: Greater responses were found for angry expressions, compared with fear and neutrality, with directed faces. When faces were averted, fear and neutrality produced larger responses compared with anger and happiness. These results are in line with the notion that startle is potentiated to stimuli signaling threat. That is, a forward directed angry face may signal a threat toward the observer, and a fearful face directed to the side may signal a possible threat in the environment.

  16. Split Hopkinson Resonant Bar Test for Sonic-Frequency Acoustic Velocity and Attenuation Measurements of Small, Isotropic Geologic Samples