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Sample records for acp journal club

  1. Journal club.

    PubMed

    1984-01-01

    Dr Janet Gale, Lecturer in the Health and Social Welfare Section at the Open University's Centre for Continuing Education, has selected eight articles which she thought might be of interest to readers of Medical Teacher. Her personal comments appear at the end of each review. New Ways with Text 'A new approach to the design of instructional text' Harden, R. M. and Sowden, S. Journal of Audiovisual Media in Medicine 1983; 6: 124-129. Effective Educational Media 'Learning from audio-visual media' Bates, T. Teaching at a Distance. Institutional Research Review, 1982; 1: 33-57. Complementary to 'Effective Educational Media' 'The differential investment of mental effort in learning from different sources' Salomon, G. Educational Psychologist 1983; 18: 42-50. Technology in Education 'The educational potential of cable television networks in the UK' Boyd-Barrett, J. O. Educational Studies 1983; 9: 221-231. Medical Education and Independent Learning 'How medical students learn' Vu, N. V. and Galofre, A. Journal of Medical Education 1983; 58: 601-610. The Teaching Personality 'Personality traits in effective clinical teachers' Kegel-Flom, P. Research in Higher Education 1983; 19: 73-82. PMID:24476410

  2. Redesigning journal club in residency.

    PubMed

    Al Achkar, Morhaf

    2016-01-01

    The gap between production and implementation of knowledge is the main reason for the suboptimal quality of health care. To eliminate this gap and improve the quality of patient care, journal club (JC) in graduate medical education provides an opportunity for learning the skills of evidence-based medicine. JC, however, continues to face many challenges mainly due to poorly defined goals, inadequate preparation, and lack of interest. This article presents an innovative model to prepare and present JC based on three pillars: dialogical learning through group discussion, mentored residents as peer teachers, and including JC as part of a structured curriculum to learn evidence-based medicine. This engaging model has the potential to transform JC from a moribund session that is daunting for residents into a lively discussion to redefine clinical practice using the most current evidence. PMID:27313486

  3. New Methods for an Undergraduate Journal Club

    ERIC Educational Resources Information Center

    Clark, Jordan M.; Rollins, Adam W.; Smith, Philip

    2014-01-01

    Journal clubs have been used to advance students' scientific skills beyond basic knowledge and comprehension, but students often view the traditional format of analyzing reported data and experimental design as laborious and intimidating. As such, the traditional approach can diminish student engagement and enthusiasm for the value of…

  4. Implementing a successful journal club in an anesthesiology residency program.

    PubMed

    Pitner, Nathaniel D; Fox, Chris A; Riess, Matthias L

    2013-01-01

    Journal clubs are an integral element of residency training. We report the successful implementation of a monthly structured journal club in our anesthesia residency program. Based on resident surveys before and one year after its start, the journal club led to a significantly higher confidence in how to critically appraise literature and present a manuscript. The journal club also improved the residents' ability to search the literature and their statistical knowledge, skills that are essential in the practice of evidence-based medicine. We describe key features that may aid other training programs in organizing a stimulating an educational and sustainable journal club. PMID:24358844

  5. The Prevalence and Practices of Academic Library Journal Clubs

    ERIC Educational Resources Information Center

    Young, Philip; Vilelle, Luke

    2011-01-01

    Increased mention of journal clubs in the library literature and the recent creation of clubs at the authors' institutions sparked curiosity about how widespread they are in academic libraries. An online survey announced on library listservs assessed their prevalence and practices. Library journal clubs promote current awareness, analysis skills,…

  6. The Use of Journal Clubs in Science Teacher Education

    ERIC Educational Resources Information Center

    Tallman, Karen A.; Feldman, Allan

    2016-01-01

    This qualitative study explored how in a 7-month-long journal club pre- and inservice science teachers engaged with education research literature relevant to their practice to reduce the theory-practice gap. In the journal club they had the opportunity to critique and analyze peer-reviewed science education articles in the context of their…

  7. Continuing medical education: merits of a surgical journal club.

    PubMed

    A-Latif, A

    1990-01-01

    Journal clubs have been used as part of a continuing medical education programme for over 100 years. The major role of a journal club is to introduce concepts of critical thinking and evaluation of research literature. This study describes how the understanding of papers presented in a surgical journal club improves by the use of a handout as an aid to revision, and reading skills of the participants are evaluated by a post-test. It shows how participation improves when a climate of mutual respect is created and when the subject under discussion answers questions related to real life needs and the new knowledge acquired has an immediate application.

  8. Beyond content: leadership development through a journal club.

    PubMed

    Kattan, Jessica A; Apostolou, Andria; Al-Samarrai, Teeb; El Bcheraoui, Charbel; Kay, Meagan K; Khaokham, Christina B; Pillai, Parvathy; Sapkota, Sanjeeb; Jani, Asim A; Koo, Denise; Taylor, William C

    2014-11-01

    CDC designed its Health Systems Integration Program to prepare leaders to function at the interface of public health and health care. Specific Health Systems Integration Program competencies in the areas of communication, analysis and assessment, and health systems were developed to nurture evidence-based decision-making and leadership skills crucial for future public health leaders. The program therefore designed an innovative journal club as part of its competency-based curriculum not only to meet the standard goals for a journal club-critical reading, interpretation, and acquiring content knowledge-but also to foster leadership development. This report describes the Health Systems Integration Program journal club format, its implementation, challenges, and key elements of success. Other programs using a journal club model as a learning format might consider using the Health Systems Integration Program's innovative approach that focuses on leadership development. PMID:25439249

  9. Social media, medicine and the modern journal club.

    PubMed

    Topf, Joel M; Hiremath, Swapnil

    2015-04-01

    Medical media is changing along with the rest of the media landscape. One of the more interesting ways that medical media is evolving is the increased role of social media in medical media's creation, curation and distribution. Twitter, a microblogging site, has become a central hub for finding, vetting, and spreading this content among doctors. We have created a Twitter journal club for nephrology that primarily provides post-publication peer review of high impact nephrology articles, but additionally helps Twitter users build a network of engaged people with interests in academic nephrology. By following participants in the nephrology journal club, users are able to stock their personal learning network. In this essay we discuss the history of medical media, the role of Twitter in the current states of media and summarize our initial experience with a Twitter journal club.

  10. Social media, medicine and the modern journal club.

    PubMed

    Topf, Joel M; Hiremath, Swapnil

    2015-04-01

    Medical media is changing along with the rest of the media landscape. One of the more interesting ways that medical media is evolving is the increased role of social media in medical media's creation, curation and distribution. Twitter, a microblogging site, has become a central hub for finding, vetting, and spreading this content among doctors. We have created a Twitter journal club for nephrology that primarily provides post-publication peer review of high impact nephrology articles, but additionally helps Twitter users build a network of engaged people with interests in academic nephrology. By following participants in the nephrology journal club, users are able to stock their personal learning network. In this essay we discuss the history of medical media, the role of Twitter in the current states of media and summarize our initial experience with a Twitter journal club. PMID:25906989

  11. The Use of Journal Clubs in Science Teacher Education

    NASA Astrophysics Data System (ADS)

    Tallman, Karen A.; Feldman, Allan

    2016-04-01

    This qualitative study explored how in a 7-month-long journal club pre- and inservice science teachers engaged with education research literature relevant to their practice to reduce the theory-practice gap. In the journal club they had the opportunity to critique and analyze peer-reviewed science education articles in the context of their classroom practice. Data sources included audio recordings of the meetings; semi-structured pre- and post-interviews of the teachers; focus groups; and artifacts (e.g., journal articles, reflective paper, email exchanges, and researcher's field notes). Data were analyzed using the techniques of grounded theory (Corbin & Strauss in Basics of qualitative research, 3rd ed. Sage, Thousand Oaks, 2008). In addition we used some preconceived categories that we created from existing literature on journal clubs and communities of practice (Newswander & Borrego in European Journal of Engineering Education 34(6): 561-571, 2009; Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) and from our previous research (Tallman & Feldman, 2012). We found that the journal club incorporated the three characteristics of a community of practice (Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) into its functioning (mutual engagement, joint enterprise, and shared repertoire). The teachers mutually engaged around the joint enterprise of reading, critiquing, and understanding the research studies with the goal of improving practice. The teachers also asked each other analytical questions, which became a shared repertoire of the journal club. They reflected on their practice by presenting, reading, and discussing the articles, which helped them to determine whether and how the findings from the articles could be incorporated into their teaching practice. In doing so, they learned the skills needed to critique the research literature in

  12. The journal club in postgraduate medical education: a systematic review.

    PubMed

    Ebbert, J O; Montori, V M; Schultz, H J

    2001-01-01

    An investigation was made as to whether studies have found journal clubs for physicians in training to be effective for improving patient. care, teaching critical appraisal skills, improving reading habits, increasing knowledge of clinical epidemiology and biostatistics, and increasing the use of medical literature in clinical practice. A literature search was undertaken using 10 databases and retrieval systems and hand searches of journals, conference proceedings and personal files. The rigor of studies meeting the inclusion criteria was analyzed using a protocol based on methods established by the Cochrane Collaboration. One randomized controlled trial found an improvement in knowledge of clinical epidemiology and biostaristics, reading habits, and the use of medical literature in practice, but no improvement in critical appraisal skills. Six less methodologically rigorous studies found possible improvement in critical appraisal skills. It is concluded that journal clubs may improve knowledge of clinical epidemiology and biostatistics, reading habits, and the use of medical literature in practice. A multi-center, randomized controlled trial of journal clubs is needed to assess whether journal clubs improve critical appraisal skills.

  13. Teaching Note--Incorporating Journal Clubs into Social Work Education: An Exploratory Model

    ERIC Educational Resources Information Center

    Moore, Megan; Fawley-King, Kya; Stone, Susan I.; Accomazzo, Sarah M.

    2013-01-01

    This article outlines the implementation of a journal club for master's and doctoral social work students interested in mental health practice. It defines educational journal clubs and discusses the history of journal clubs in medical education and the applicability of the model to social work education. The feasibility of implementing…

  14. Journal Club Format Emphasizing Techniques of Critical Reading.

    ERIC Educational Resources Information Center

    Woods, James R., Jr.; Winkel, Craig E.

    1982-01-01

    The journal club format offers the resident a unique opportunity to develop specific skills in reading, comprehending, and evaluating medical literature. A course designed for residents in obstetrics and gynecology at the Letterman Army Medical Center and at the University of Cincinnati is described. (MLW)

  15. Biology Blogs: An Online Journal Club & Assessment Tool

    ERIC Educational Resources Information Center

    De Souza-Hart, Janet A.

    2010-01-01

    A "blog" can be used as an online journal club to supplement classroom learning. When crafted in a certain way, it can help students develop their scientific reading comprehension, critical thinking, and writing skills in a way that can easily be assessed by educators.

  16. Interdisciplinary Journal Club: Advancing Knowledge Translation in a Rural State

    ERIC Educational Resources Information Center

    Dennis, Ruth E.; Potvin, Marie-Christine; MacLeod, Marie

    2010-01-01

    Professionals who provide health and related supports and services to children with disabilities in educational programs and community settings must practice in an evidence-based manner to ensure children and families receive the highest quality care. Vermont's Interdisciplinary Journal Club provides a successful approach to supporting…

  17. Chinese Obstetrics & Gynecology journal club: a randomised controlled trial

    PubMed Central

    Tsui, Ilene K; Dodson, William C; Kunselman, Allen R; Kuang, Hongying; Han, Feng-Juan; Legro, Richard S; Wu, Xiao-Ke

    2016-01-01

    Objectives To assess whether a journal club model could improve comprehension and written and spoken medical English in a population of Chinese medical professionals. Setting and participants The study population consisted of 52 medical professionals who were residents or postgraduate master or PhD students in the Department of Obstetrics and Gynecology, Heilongjiang University of Chinese Medicine, China. Intervention After a three-part baseline examination to assess medical English comprehension, participants were randomised to either (1) an intensive journal club treatment arm or (2) a self-study group. At the conclusion of the 8-week intervention participants (n=52) were re-tested with new questions. Outcome measures The primary outcome was the change in score on a multiple choice examination. Secondary outcomes included change in scores on written and oral examinations which were modelled on the Test of English as a Foreign Language (TOEFL). Results Both groups had improved scores on the multiple choice examination without a statistically significant difference between them (90% power). However, there was a statistically significant difference between the groups in mean improvement in scores for both written (95% CI 1.1 to 5.0; p=0.003) and spoken English (95% CI 0.06 to 3.7; p=0.04) favouring the journal club intervention. Conclusions Interacting with colleagues and an English-speaking facilitator in a journal club improved both written and spoken medical English in Chinese medical professionals. Journal clubs may be suitable for use as a self-sustainable teaching model to improve fluency in medical English in foreign medical professionals. Trial registration number NCT01844609. PMID:26823180

  18. Journal club: an opportunity to advance the art and science of home health practice.

    PubMed

    Fowler, Susan B; Druist, Kim A; Dillon-Zwerdling, Lisa

    2011-01-01

    A journal club is more than a club. It is an opportunity for staff to gather, learn, share, brainstorm, challenge thinking and ways of doing business, and set future direction. These activities have the potential to advance the art and science of nursing and other disciplines. Developing and implementing a successful journal club requires planning, communication, facilitation, and evaluation.

  19. ASBMB Journal Club - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    On Wednesday, November 12, 2014 from 2:00 PM to 3:00 PM EST, Daniel Liebler, PhD (Vanderbilt University) and Karin Rodland, PhD (Pacific Northwestern National Laboratory) and Ruedi Aebersold, PhD (Swiss Federal Institute of Technology) will share their research insight as part of the ASBMB Journal Club.  Both Doctors Liebler and Rodland are Principal Investigators in the NCI’s Clinical Proteomic Tumor Analysis Consortium.

  20. [An interdisciplinary journal club improves hospital staff competence and commitment].

    PubMed

    Qvist, Ina; Østergaard, Mie; Aarhus, Rikke; Mikkelsen, Lone Ramer; Jørgensen, Lene Bastrup

    2015-02-01

    The demands of the health-care sector for quality and evidence-based knowledge require nurses, secretaries and allied health-care professionals to keep up to date professionally. An interdisciplinary journal club (IJC) provides a self-reported improvement in the competence of critical reading as well as increasing knowledge about research designs and research methods. Furthermore, IJC leads to an increased sense of community, understanding of an interdisciplinary culture and appears to strengthen the foundations for cooperation across disciplines. PMID:25650578

  1. Undergraduate Journal Club as an Intervention to Improve Student Development in Applying the Scientific Process

    ERIC Educational Resources Information Center

    Sandefur, Conner I.; Gordy, Claire

    2016-01-01

    We developed and implemented a series of workshops and seminars in an undergraduate journal club targeted at improving student development in applying the scientific process. Students were surveyed before and after participating in the club about their confidence in accessing, analyzing, and reporting scientific research. Post-club, the students…

  2. Undergraduate journal club as an intervention to improve student development in applying the scientific process

    PubMed Central

    Sandefur, Conner I; Gordy, Claire

    2016-01-01

    Active learning improves student performance in STEM courses. Exposure to active learning environments generally occurs through traditional laboratory courses and independent research, both of which require access to resources that are limited at many universities. A previously reported active learning-based undergraduate journal club improved student achievement in communicating science. Here, we expanded on this previous journal club to improve student performance in the process of science. We developed and implemented a series of workshops and seminars referred to as “CASL Club,” an undergraduate journal club targeted at improving student development in applying the scientific process. Students were surveyed before and after CASL club about their confidence in accessing, analyzing, and reporting scientific research. Post-CASL club, the students reported increases in confidence in their abilities to access and present scientific articles and write scientific abstracts. Additionally, the students reported improved confidence and performance in their courses. Compared to the previous journal club study, the majority of sampled journal club participants were not exposed to primary literature as part of their general coursework. Our results illustrate active-learning based undergraduate journal clubs as a way to expose students to primary literature and improve students’ ability to apply scientific process in an active-learning environment at resource-limited universities. PMID:27212737

  3. Journal Clubs During Advanced Pharmacy Practice Experiences to Teach Literature-Evaluation Skills

    PubMed Central

    Gim, Suzanna; Nogid, Anna; Shah, Bupendra

    2012-01-01

    Objective. To determine pharmacy students’ attitudes and academic performance related to journal club during 2 advanced pharmacy practice experiences (APPEs). Design. Fourth-year pharmacy students were required to complete 3 journal club assignments during drug information and internal medicine APPEs. Assessment. A majority (91.3%) of the 105 students who responded to a 21-item survey instrument indicated that journal club assignments during the drug-information APPE were valuable to their understanding of research design and statistics. Students who completed the drug-information APPE before the internal medicine APPE scored higher on their understanding of the strengths and weaknesses and the clinical relevance of studies and had a higher learning slope (p = 0.01) than did students who completed the internal medicine APPE first. Conclusion. Incorporating journal clubs into APPEs is an effective means of teaching literature-evaluation skills to pharmacy students. PMID:22761529

  4. Globalization of Continuing Professional Development by Journal Clubs via Microblogging: A Systematic Review

    PubMed Central

    Perera, Marlon; Lawrentschuk, Nathan; Romanic, Diana; Papa, Nathan; Bolton, Damien

    2015-01-01

    Background Journal clubs are an essential tool in promoting clinical evidence-based medical education to all medical and allied health professionals. Twitter represents a public, microblogging forum that can facilitate traditional journal club requirements, while also reaching a global audience, and participation for discussion with study authors and colleagues. Objective The aim of the current study was to evaluate the current state of social media–facilitated journal clubs, specifically Twitter, as an example of continuing professional development. Methods A systematic review of literature databases (Medline, Embase, CINAHL, Web of Science, ERIC via ProQuest) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search of Twitter, the followers of identified journal clubs, and Symplur was also performed. Demographic and monthly tweet data were extracted from Twitter and Symplur. All manuscripts related to Twitter-based journal clubs were included. Statistical analyses were performed in MS Excel and STATA. Results From a total of 469 citations, 11 manuscripts were included and referred to five Twitter-based journal clubs (#ALiEMJC, #BlueJC, #ebnjc, #urojc, #meded). A Twitter-based journal club search yielded 34 potential hashtags/accounts, of which 24 were included in the final analysis. The median duration of activity was 11.75 (interquartile range [IQR] 19.9, SD 10.9) months, with 7 now inactive. The median number of followers and participants was 374 (IQR 574) and 157 (IQR 272), respectively. An overall increasing establishment of active Twitter-based journal clubs was observed, resulting in an exponential increase in total cumulative tweets (R 2=.98), and tweets per month (R 2=.72). Cumulative tweets for specific journal clubs increased linearly, with @ADC_JC, @EBNursingBMJ, @igsjc, @iurojc, and @NephJC, and showing greatest rate of change, as well as total impressions per month since

  5. Effect of changing journal clubs from traditional method to evidence-based method on psychiatry residents

    PubMed Central

    Faridhosseini, Farhad; Saghebi, Ali; Khadem-Rezaiyan, Majid; Moharari, Fatemeh; Dadgarmoghaddam, Maliheh

    2016-01-01

    Introduction Journal club is a valuable educational tool in the medical field. This method follows different goals. This study aims to investigate the effect on psychiatry residents of changing journal clubs from the traditional method to the evidence-based method. Method This study was conducted using a before–after design. First- and second-year residents of psychiatry were included in the study. First, the status quo was evaluated by standardized questionnaire regarding the effect of journal club. Then, ten sessions were held to familiarize the residents with the concept of journal club. After that, evidence-based journal club sessions were held. The questionnaire was given to the residents again after the final session. Data were analyzed through descriptive statistics (frequency and percentage frequency, mean and standard deviation), and analytic statistics (paired t-test) using SPSS 22. Results Of a total of 20 first- and second-year residents of psychiatry, the data of 18 residents were finally analyzed. Most of the subjects (17 [93.7%]) were females. The mean overall score before and after the intervention was 1.83±0.45 and 2.85±0.57, respectively, which showed a significant increase (P<0.001). Conclusion Moving toward evidence-based journal clubs seems like an appropriate measure to reach the goals set by this educational tool. PMID:27570469

  6. Journal Club: A Forum to Encourage Graduate and Undergraduate Research Students to Critically Review the Literature

    ERIC Educational Resources Information Center

    Minerick, Adrienne R.

    2011-01-01

    This contribution outlines a strategy to counteract literature lethargy and train beginning and continuing undergraduate and graduate researchers in a professor's research group to efficiently learn from and critique archival journal articles. Journal Club is a weekly one-credit-hour class where a research article related to each research…

  7. Twitter-Augmented Journal Club: Educational Engagement and Experience So Far.

    PubMed

    Udani, Ankeet D; Moyse, Daniel; Peery, Charles Andrew; Taekman, Jeffrey M

    2016-04-15

    Social media is a nascent medical educational technology. The benefits of Twitter include (1) easy adoption; (2) access to experts, peers, and patients across the globe; (3) 24/7 connectivity; (4) creation of virtual, education-based communities using hashtags; and (5) crowdsourcing information using retweets. We report on a novel Twitter-augmented journal club for anesthesia residents: its design, implementation, and impact. Our inaugural anesthesia Twitter-augmented journal club succeeded in engaging the anesthesia community and increasing residents' professional use of Twitter. Notably, our experience suggests that anesthesia residents are willing to use social media for their education. PMID:26579611

  8. Use of a Journal Club for Professional Development: Outcomes in a School-Based Occupational Therapy Practice

    ERIC Educational Resources Information Center

    Szucs, Kimberly A.; Benson, Jeryl D.; Corturillo, Amanda

    2016-01-01

    This article investigates the outcomes of a journal club on the evidence-based practice (EBP) skills of school-based practitioners. Participants' knowledge, attitudes, and perceptions of EBP were collected using pre- and postsurveys following 6 monthly journal club sessions. Participants identified time, availability of articles, and decreased…

  9. Journal Clubs and Case Conferences: From Academic Tradition to Communities of Practice

    ERIC Educational Resources Information Center

    Price, David W.; Felix, Kate G.

    2008-01-01

    Introduction: As small group learning sessions, Journal Clubs (JCs) and Case Conferences (CCs), if structured interactively, have potential as educational formats that can change practice. However, the degree to which these formats, as currently typically structured, lead to practice change is unknown. Methods: We used concepts of communities of…

  10. The Research Journal Club: Pedagogy of Research in the Preparation of Students in Educational Leadership

    ERIC Educational Resources Information Center

    Bowers, Alex J.; Murakami-Ramalho, Elizabeth

    2010-01-01

    Following calls to increase professional communities of practice around research in educational leadership graduate programs, this study describes the ongoing process of creating a research journal club. We share the process of implementation, describe the structure adopted, and the outcomes observed one year after the establishment of a journal…

  11. A Journal-Club-Based Class that Promotes Active and Cooperative Learning of Biology

    ERIC Educational Resources Information Center

    Kitazono, Ana A.

    2010-01-01

    A journal-club-based class has been developed to promote active and cooperative learning and expose seniors in biochemistry and cellular molecular biology to recent research in the field. Besides giving oral presentations, students also write three papers: one discussing an article of their own choosing and two, discussing articles presented by…

  12. ICTs as Placed Resources in a Rural Kenyan Secondary School Journalism Club

    ERIC Educational Resources Information Center

    Kendrick, Maureen; Chemjor, Walter; Early, Margaret

    2012-01-01

    In this study, we draw on three interrelated concepts, i.e. placed resources, multiliteracies and the carnivalesque, to understand how information and communication technology (ICT) resources are taken up within the context of a print-based journalism club. Our research participants attend an under-resourced girls' residential secondary school in…

  13. Evidence-based nursing leadership: Evaluation of a Joint Academic-Service Journal Club.

    PubMed

    Duffy, Joanne R; Thompson, Diane; Hobbs, Terry; Niemeyer-Hackett, Nancy Lee; Elpers, Susan

    2011-10-01

    This article describes the importance of evidence-based nursing leadership in the development and evaluation of a joint academic-service nursing leadership journal club. The use of scientific evidence and the embracing of an environment of continuous learning are essential to quality practice; however, nursing leadership has been slow to apply evidence-based practice to their own work. A noontime monthly meeting schedule, incentivized by lunch, was organized as a nursing leadership journal club. Articles were selected and reviewed monthly, and the process was formally evaluated using a written evaluation at the end of year 1. Eighteen articles were appraised by the group with 6 topics identified. Positive results included increased knowledge, competence of the leader, and attainment of goals. Recommendations include revision of goals, plans to share leadership of the group, development of a rigorous evaluation of outcomes, and dissemination of findings. The journal club was valuable in increasing awareness of nursing leadership research, promoting leadership development, and improving competence in the performance of research appraisals. Process improvement and further study are needed to increase understanding regarding the benefits of leadership journal clubs. PMID:21934429

  14. Evidence-based nursing leadership: Evaluation of a Joint Academic-Service Journal Club.

    PubMed

    Duffy, Joanne R; Thompson, Diane; Hobbs, Terry; Niemeyer-Hackett, Nancy Lee; Elpers, Susan

    2011-10-01

    This article describes the importance of evidence-based nursing leadership in the development and evaluation of a joint academic-service nursing leadership journal club. The use of scientific evidence and the embracing of an environment of continuous learning are essential to quality practice; however, nursing leadership has been slow to apply evidence-based practice to their own work. A noontime monthly meeting schedule, incentivized by lunch, was organized as a nursing leadership journal club. Articles were selected and reviewed monthly, and the process was formally evaluated using a written evaluation at the end of year 1. Eighteen articles were appraised by the group with 6 topics identified. Positive results included increased knowledge, competence of the leader, and attainment of goals. Recommendations include revision of goals, plans to share leadership of the group, development of a rigorous evaluation of outcomes, and dissemination of findings. The journal club was valuable in increasing awareness of nursing leadership research, promoting leadership development, and improving competence in the performance of research appraisals. Process improvement and further study are needed to increase understanding regarding the benefits of leadership journal clubs.

  15. Charting the Course for a Nursing Online Journal Club: Part II.

    PubMed

    Moonan, Marilyn; Bukoye, Bola; Clapp, Alison; Shermont, Herminia; O'Sullivan Oliveira, Joanne

    2016-01-01

    In a pediatric inpatient setting, an interdisciplinary team designed and implemented an online journal club to discuss current nursing trends and research, as well as to foster evidence-based practice. This article is Part II of a two-part series in which the implementation process is described. PMID:26790492

  16. Charting the Course for a Nursing Online Journal Club: Part I.

    PubMed

    Moonan, Marilyn; Bukoye, Bola; Clapp, Alison; Shermont, Herminia; Oliveira, Joanne O'Sullivan

    2015-12-01

    In a pediatric inpatient setting, an interdisciplinary team designed and implemented an online journal club to discuss current nursing trends and research and to foster evidence-based practice. This article is Part I of a two-part series in which the process will be described. PMID:26641151

  17. Classroom Journal Club: Collaborative Study of Contemporary Primary Literature in the Biomechanics Classroom.

    PubMed

    Kuxhaus, Laurel; Corbiere, Nicole C

    2016-07-01

    Current engineering pedagogy primarily focuses on developing technical proficiency and problem solving skills; the peer-review process for sharing new research results is often overlooked. The use of a collaborative classroom journal club can engage students with the excitement of scientific discovery and the process of dissemination of research results, which are also important lifelong learning skills. In this work, a classroom journal club was implemented and a survey of student perceptions spanning three student cohorts was collected. In this collaborative learning activity, students regularly chose and discussed a recent biomechanics journal article, and were assessed based on specific, individual preparation tasks. Most student-chosen journal articles were relevant to topics discussed in the regular class lecture. Surveys assessed student perceptions of the activity. The survey responses show that, across all cohorts, students both enjoyed the classroom journal club and recognized it as an important learning experience. Many reported discussing their journal articles with others outside of the classroom, indicating good engagement. The results demonstrate that student engagement with primary literature can foster both technical knowledge and lifelong learning skills.

  18. Classroom Journal Club: Collaborative Study of Contemporary Primary Literature in the Biomechanics Classroom.

    PubMed

    Kuxhaus, Laurel; Corbiere, Nicole C

    2016-07-01

    Current engineering pedagogy primarily focuses on developing technical proficiency and problem solving skills; the peer-review process for sharing new research results is often overlooked. The use of a collaborative classroom journal club can engage students with the excitement of scientific discovery and the process of dissemination of research results, which are also important lifelong learning skills. In this work, a classroom journal club was implemented and a survey of student perceptions spanning three student cohorts was collected. In this collaborative learning activity, students regularly chose and discussed a recent biomechanics journal article, and were assessed based on specific, individual preparation tasks. Most student-chosen journal articles were relevant to topics discussed in the regular class lecture. Surveys assessed student perceptions of the activity. The survey responses show that, across all cohorts, students both enjoyed the classroom journal club and recognized it as an important learning experience. Many reported discussing their journal articles with others outside of the classroom, indicating good engagement. The results demonstrate that student engagement with primary literature can foster both technical knowledge and lifelong learning skills. PMID:26902674

  19. journal club for peer mentorship: helping to navigate the transition to independent practice.

    PubMed

    MacMillan, Thomas E; Rawal, Shail; Cram, Peter; Liu, Jessica

    2016-10-01

    The transition from residency to independent practice presents unique challenges for physicians. New attending physicians often have unmet learning needs in non-clinical domains. An attending physician is an independent medical practitioner, sometimes referred to as a staff physician or consultant. Peer mentorship has been explored as an alternative to traditional mentorship to meet the learning needs of new attendings. In this article, the authors describe how a journal club for general internal medicine fellowship graduates helped ease the transition by facilitating peer mentorship. Journal club members were asked to bring two things to each meeting: a practice-changing journal article, and a 'transition to practice' discussion topic such as a diagnostic dilemma, billing question, or a teaching challenge. Discussions fell into three broad categories that the authors have termed: trading war stories, measuring up, and navigating uncharted waters. It is likely that physicians have a strong need for peer mentorship in the first few years after the transition from residency, and a journal club or similar discussion group may be one way to fulfil this. PMID:27631332

  20. Journal Clubs: An Educational Approach to Advance Understanding among Community Partners and Academic Researchers about CBPR and Cancer Health Disparities

    PubMed Central

    Vadaparampil, Susan T.; Simmons, Vani N.; Lee, Ji-Hyun; Malo, Teri; Klasko, Lynne; Rodriguez, Maria; Waddell, Rhonda; Gwede, Clement K.; Meade, Cathy D.

    2014-01-01

    Background Journal clubs may enhance the knowledge and skills necessary to engage in community-based participatory research (CBPR) that will ultimately impact cancer health disparities. This article: (1) describes an innovative approach to adapting the traditional journal club format to meet community and academic participants’ needs, (2) presents evaluation data, and (3) explores whether responses differed between academic and community members. Methods Five journal clubs occurred between February 2011 and May 2012 as a training activity of a regional cancer health disparities initiative. Each journal club was jointly planned and facilitated by an academic member in collaboration with a community partner. Attendees were recruited from academic programs across the Moffitt Cancer Center/university and community partners. Responses to a 13-item evaluation of each journal club session were compared to assess whether certain topics were evaluated more favorably, and explore differences between academic and community participants’ assessment of the topic relevance. Results Evaluations were positive (mean ratings >4 out of 5) on most items and overall. No statistically significant differences were observed between academic and community members’ ratings. Key overlapping interests by community partners and academic researchers/trainees for future journal club topics included discussing real-world CBPR examples and methods for involving the community in research. Conclusions Although the initial goal was to use journal clubs as an educational tool to increase CBPR knowledge and skills of junior faculty trainees, results suggest mutual academic-community benefit and interest in learning more about CBPR as a way to reduce cancer health disparities. PMID:24078328

  1. Refining the Journal Club Presentations of Postgraduate Students in Seven Clinical Departments for Better Evidence-based Practice

    PubMed Central

    Herur, A; Kolagi, S; Ramadurg, U; Hiremath, CS; Hadimani, CP; Goudar, SS

    2016-01-01

    Background: A gap between best practice and actual clinical care exists and this can be overcome by evidence-based practice (EBP), which is essential to improve the clinical decision making. A strategy to reduce deficits in care provision is to train the postgraduate students in the practice of EBP in the journal clubs as evidence from medical colleges in India reveals that current format of journal club presentations is unsatisfactory. Aim: The aim of the present study was to refine the journal club presentations of postgraduate students of clinical departments and to study the effectiveness of EBP training in them for better EBP. Subjects and Methods: This study was conducted in S. Nijalingappa Medical College, Bagalkot, Karnataka, India, and it was a pre- and post-trial. This study was a pre- and post-trial done during the journal club presentations of postgraduate students from clinical departments. Postgraduate students' understanding of concepts about EBP was assessed using Fresno test questionnaire in traditional journal club presentation. A hands-on session incorporating steps of EBP was imparted to them. Soon after the session, each student was assessed. In the next journal club presentation, 1 week later, the students were assessed again with the same questionnaire by the same faculty. Scores of the postgraduate students, before and after intervention (immediate and 1 week later), were compared. Data were analyzed by paired t-test using SPSS. Results: An increase in mean posttest scores was seen immediately and also 1 week later as compared to the pretest scores. The scores also increased significantly, when each step of EBP was considered. Conclusions: Incorporating teaching of EBP in journal club presentations improved the competencies of postgraduate students in clinical decision making. PMID:27398252

  2. Journal club.

    PubMed

    1982-01-01

    Professor Michael A. Simpson, Professor of Psychiatry and Professor of Family Practice and Community Health at Temple University, Philadelphia, has selected six articles which he thought might be of interest to readers of Medical Teacher. His personal comments appear at the end of each review. Cueing in Clinical Examinations 'Clinical evaluation: issues of examination format' Blumberg, P. Evaluation and the Health Professions, 1981; 4: 316-329. Content of Ward Rounds 'Parent talk at intensive care unit rounds' Frader, J. E. and Bosk, C. L. Social Science and Medicine 1981; 15E: 267-274. Anxiety in Oral Examinations 'Anxiety and performance in oral examinations' Lin, B. S. and Zippo, R. Social Science and Medicine 1981; 15E: 211-214. Effects of Small Groups 'Peer group learning in higher education: the development of higher-order skills' Collier, K. G. Studies in Higher Education 1980; 5: 55-62. Faculty Evaluation 'The role of evaluation in faculty development' Braskamp, L. A. Studies of Higher Education 1980; 5: 45-53. Note Taking 'Note taking: a significant and integral part of learning environments' Gauske, L. Educational Communication and Technology 1981; 29: 155-175.

  3. ‘Research clinics’: online journal clubs between south and north for student mentoring

    PubMed Central

    Atkins, Salla; Varshney, Dinansha; Meragia, Elnta; Zwarenstein, Merrick; Diwan, Vishal

    2016-01-01

    Background Capacity development in health research is high on the agenda of many low- and middle-income countries. Objective The ARCADE projects, funded by the EU, have been working in Africa and Asia since 2011 in order to build postgraduate students’ health research capacity. In this short communication, we describe one initiative in these projects, that of research clinics – online journal clubs connecting southern and northern students and experts. Design We describe the implementation of these research clinics together with student and participant experiences. Results From 2012 to 2015, a total of seven journal clubs were presented by students and junior researchers on topics related to global health. Sessions were connected through web conferencing, connecting experts and students from different countries. Conclusions The research clinics succeeded in engaging young researchers across the globe and connecting them with global experts. The contacts and suggestions made were appreciated by students. This format has potential to contribute toward research capacity building in low- and middle-income countries. PMID:27725079

  4. A research and journal club: a medium for teaching, professional development and networking.

    PubMed

    Hammick, M

    1995-03-01

    The establishment of a monthly Radiography Research and Journal Club has helped to meet the educational and professional development needs of students and qualified staff in a changing teaching and learning environment. The introduction of degree education presented opportunities for new, student centred learning styles within the pre-registration therapeutic radiography course offered by The Royal Marsden NHS Trust and Kingston University. At the same time the need to provide a forum for academic and clinical staff to learn about the research process in general and current work in radiography and oncology in particular was recognized. A varied, and practitioner-led, programme for the Club and a flexible approach ensures maximum participation. The review of a journal article about telephone counselling for cancer patients and the ensuing discussion is given as an example of the value of one such meeting. The topic raised issues related to current practice and the research methods used provoked a number of questions. As the result of the discussion two of the participants are involved in a research project on a related issue.

  5. Dietetic Professionals' Perceptions of the Learning Environment, Perceived Learning, and Actual Learning of Online and Face-to-Face Journal Clubs

    ERIC Educational Resources Information Center

    Schumacher, Julie Raeder

    2009-01-01

    A journal club is defined as a group of individuals who meet regularly to discuss current trends in literature and have been advocated to bridge the gap of research and practice. With the popularity of the Internet, there are a variety of tools available for online learning through journal clubs including asynchronous discussions, which the…

  6. Improving Journal Club: Increasing Student Discussion and Understanding of Primary Literature in Molecular Biology through the Use of Dialectical Notes

    ERIC Educational Resources Information Center

    McDonough, Virginia

    2012-01-01

    Reading the primary literature in a journal club format is an excellent practice where undergraduate students can develop their abilities in experimental data analysis and critical thinking, learn about new ideas and methods, and gain a foothold in scientific discourse. However, students are not familiar with the format, writing style, and depth…

  7. A Journal Club Workshop that Teaches Undergraduates a Systematic Method for Reading, Interpreting, and Presenting Primary Literature

    ERIC Educational Resources Information Center

    Robertson, Katherine

    2012-01-01

    For success after graduation, science undergraduates must master a number of skills such as scientific literacy (interpretation and evaluation of primary research articles) and effective communication. Many researchers have recognized the benefits of journal clubs in developing such skills, and a large body of literature describes how they may be…

  8. Role of Evidence-Based Reviews in Surgery in teaching critical appraisal skills and in journal clubs

    PubMed Central

    Ahmadi, Negar; Dubois, Luc; McKenzie, Marg; Brown, Carl J.; MacLean, Anthony R.; McLeod, Robin S.

    2013-01-01

    Background Evidence-Based Reviews in Surgery (EBRS) is a program developed to teach critical appraisal skills to general surgeons and residents. The purpose of this study was to assess the use of EBRS by general surgery residents across Canada and to assess residents’ opinions regarding EBRS and journal clubs. Methods We surveyed postgraduate year 2–5 residents from 15 general surgery programs. Data are presented as percentages and means. Results A total of 231 residents (58%, mean 56% per program, range 0%–100%) responded: 172 (75%) residents indicated that they know about EBRS and that it is used in their programs. More than 75% of residents who use EBRS agreed or strongly agreed that the EBRS clinical and methodological articles and reviews are relevant. Only 55 residents (24%) indicated that they used EBRS online. Most residents (198 [86%]) attend journal clubs. The most common format is a mandatory meeting held at a special time every month with faculty members with epidemiological and clinical expertise. Residents stated that EBRS articles were used exclusively (13%) or in conjunction with other articles (57%) in their journal clubs. Most respondents (176 of 193 [91%]) stated that journal clubs are very or somewhat valuable to their education. Conclusion The EBRS program is widely used among general surgery residents across Canada. Although most residents who use EBRS rate it highly, a large proportion are unaware of EBRS online features. Thus, future efforts to increase awareness of EBRS online features and increase its accessibility are required. PMID:23883511

  9. Using architectures for semantic interoperability to create journal clubs for emergency response

    SciTech Connect

    Powell, James E; Collins, Linn M; Martinez, Mark L B

    2009-01-01

    In certain types of 'slow burn' emergencies, careful accumulation and evaluation of information can offer a crucial advantage. The SARS outbreak in the first decade of the 21st century was such an event, and ad hoc journal clubs played a critical role in assisting scientific and technical responders in identifying and developing various strategies for halting what could have become a dangerous pandemic. This research-in-progress paper describes a process for leveraging emerging semantic web and digital library architectures and standards to (1) create a focused collection of bibliographic metadata, (2) extract semantic information, (3) convert it to the Resource Description Framework /Extensible Markup Language (RDF/XML), and (4) integrate it so that scientific and technical responders can share and explore critical information in the collections.

  10. The use of a virtual learning environment in promoting virtual journal clubs and case-based discussions in trauma and orthopaedic postgraduate medical education: the Leicester experience.

    PubMed

    Palan, J; Roberts, V; Bloch, B; Kulkarni, A; Bhowal, B; Dias, J

    2012-09-01

    The use of journal clubs and, more recently, case-based discussions in order to stimulate debate among orthopaedic surgeons lies at the heart of orthopaedic training and education. A virtual learning environment can be used as a platform to host virtual journal clubs and case-based discussions. This has many advantages in the current climate of constrained time and diminishing trainee and consultant participation in such activities. The virtual environment model opens up participation and improves access to journal clubs and case-based discussions, provides reusable educational content, establishes an electronic record of participation for individuals, makes use of multimedia material (including clinical imaging and photographs) for discussion, and finally, allows participants to link case-based discussions with relevant papers in the journal club. The Leicester experience highlights the many advantages and some of the potential difficulties in setting up such a virtual system and provides useful guidance for those considering such a system in their own training programme. As a result of the virtual learning environment, trainee participation has increased and there is a trend for increased consultant input in the virtual journal club and case-based discussions. It is likely that the use of virtual environments will expand to encompass newer technological approaches to personal learning and professional development.

  11. The use of a virtual learning environment in promoting virtual journal clubs and case-based discussions in trauma and orthopaedic postgraduate medical education: the Leicester experience.

    PubMed

    Palan, J; Roberts, V; Bloch, B; Kulkarni, A; Bhowal, B; Dias, J

    2012-09-01

    The use of journal clubs and, more recently, case-based discussions in order to stimulate debate among orthopaedic surgeons lies at the heart of orthopaedic training and education. A virtual learning environment can be used as a platform to host virtual journal clubs and case-based discussions. This has many advantages in the current climate of constrained time and diminishing trainee and consultant participation in such activities. The virtual environment model opens up participation and improves access to journal clubs and case-based discussions, provides reusable educational content, establishes an electronic record of participation for individuals, makes use of multimedia material (including clinical imaging and photographs) for discussion, and finally, allows participants to link case-based discussions with relevant papers in the journal club. The Leicester experience highlights the many advantages and some of the potential difficulties in setting up such a virtual system and provides useful guidance for those considering such a system in their own training programme. As a result of the virtual learning environment, trainee participation has increased and there is a trend for increased consultant input in the virtual journal club and case-based discussions. It is likely that the use of virtual environments will expand to encompass newer technological approaches to personal learning and professional development. PMID:22933486

  12. Evidence-based Medicine versus the Conventional Approach to Journal Club Sessions: Which One Is More Successful in Teaching Critical Appraisal Skills?

    PubMed Central

    Alavi-Moghaddam, Mostafa; Yazdani, Shahram; Mortazavi, Fathie; Chichi, Samira

    2016-01-01

    This study aimed to compare evidence-based medicine (EBM) vs. conventional approaches to journal club sessions in teaching critical appraisal skills in reading papers by emergency medicine residents. This double cut off discontinuation regression quasi-experimental study was conducted among emergency medicine residents. EBM vs. the conventional approach were applied to teach critical appraisal skills for half of the residents as an experimental group and another half as a control group respectively. Both groups participated in one hour monthly journal club sessions for six months. Before and after the study, all participants were examined by two tests: the Fresno Test (FT) [to evaluate their knowledge about EBM] and the Critical Appraisal Skills Test (CAST) [to evaluate their competency with critical appraisal skills]. The allocation of the participants into the experimental or control groups was according to their CAST scores before the study. 50 emergency medicine residents participated. After the study, the scores of both groups in the FT and CAST significantly improved (p<0.01), and the promotion of scores of the FT and CAST in the experimental group were more than that of the conventional group (p<0.0001). The current study indicated that an evidence-based medicine approach in journal club sessions was comparatively more advantageous compared to the conventional approach in teaching critical appraisal skills for reading papers among the residents of emergency medicine. PMID:27231674

  13. Evidence-based Medicine versus the Conventional Approach to Journal Club Sessions: Which One Is More Successful in Teaching Critical Appraisal Skills?

    PubMed

    Alavi-Moghaddam, Mostafa; Yazdani, Shahram; Mortazavi, Fathie; Chichi, Samira; Hosseini-Zijoud, Seyed-Mostafa

    2016-05-01

    This study aimed to compare evidence-based medicine (EBM) vs. conventional approaches to journal club sessions in teaching critical appraisal skills in reading papers by emergency medicine residents. This double cut off discontinuation regression quasi-experimental study was conducted among emergency medicine residents. EBM vs. the conventional approach were applied to teach critical appraisal skills for half of the residents as an experimental group and another half as a control group respectively. Both groups participated in one hour monthly journal club sessions for six months. Before and after the study, all participants were examined by two tests: the Fresno Test (FT) [to evaluate their knowledge about EBM] and the Critical Appraisal Skills Test (CAST) [to evaluate their competency with critical appraisal skills]. The allocation of the participants into the experimental or control groups was according to their CAST scores before the study. 50 emergency medicine residents participated. After the study, the scores of both groups in the FT and CAST significantly improved (p<0.01), and the promotion of scores of the FT and CAST in the experimental group were more than that of the conventional group (p<0.0001). The current study indicated that an evidence-based medicine approach in journal club sessions was comparatively more advantageous compared to the conventional approach in teaching critical appraisal skills for reading papers among the residents of emergency medicine.

  14. Evidence-based Medicine versus the Conventional Approach to Journal Club Sessions: Which One Is More Successful in Teaching Critical Appraisal Skills?

    PubMed

    Alavi-Moghaddam, Mostafa; Yazdani, Shahram; Mortazavi, Fathie; Chichi, Samira; Hosseini-Zijoud, Seyed-Mostafa

    2016-05-01

    This study aimed to compare evidence-based medicine (EBM) vs. conventional approaches to journal club sessions in teaching critical appraisal skills in reading papers by emergency medicine residents. This double cut off discontinuation regression quasi-experimental study was conducted among emergency medicine residents. EBM vs. the conventional approach were applied to teach critical appraisal skills for half of the residents as an experimental group and another half as a control group respectively. Both groups participated in one hour monthly journal club sessions for six months. Before and after the study, all participants were examined by two tests: the Fresno Test (FT) [to evaluate their knowledge about EBM] and the Critical Appraisal Skills Test (CAST) [to evaluate their competency with critical appraisal skills]. The allocation of the participants into the experimental or control groups was according to their CAST scores before the study. 50 emergency medicine residents participated. After the study, the scores of both groups in the FT and CAST significantly improved (p<0.01), and the promotion of scores of the FT and CAST in the experimental group were more than that of the conventional group (p<0.0001). The current study indicated that an evidence-based medicine approach in journal club sessions was comparatively more advantageous compared to the conventional approach in teaching critical appraisal skills for reading papers among the residents of emergency medicine. PMID:27231674

  15. JGME-ALiEM Hot Topics in Medical Education Online Journal Club: An Analysis of a Virtual Discussion About Resident Teachers

    PubMed Central

    Sherbino, Jonathan; Joshi, Nikita; Lin, Michelle

    2015-01-01

    Background  In health professionals' education, senior learners play a key role in the teaching of junior colleagues. Objective  We describe an online discussion about residents as teachers to highlight the topic and the online journal club medium. Methods  In January 2015, the Journal of Graduate Medical Education (JGME) and the Academic Life in Emergency Medicine blog facilitated an open-access, online, weeklong journal club on the JGME article “What Makes a Great Resident Teacher? A Multicenter Survey of Medical Students Attending an Internal Medicine Conference.” Social media platforms used to promote asynchronous discussions included a blog, a video discussion via Google Hangouts on Air, and Twitter. We performed a thematic analysis of the discussion. Web analytics were captured as a measure of impact. Results  The blog post garnered 1324 page views from 372 cities in 42 countries. Twitter was used to endorse discussion points, while blog comments provided opinions or responded to an issue. The discussion focused on why resident feedback was devalued by medical students. Proposed explanations included feedback not being labeled as such, the process of giving delivery, the source of feedback, discrepancies with self-assessment, and threats to medical student self-image. The blog post resulted in a crowd-sourced repository of resident teacher resources. Conclusions  An online journal club provides a novel discussion forum across multiple social media platforms to engage authors, content experts, and the education community. Crowd-sourced analysis of the resident teacher role suggests that resident feedback to medical students is important, and barriers to student acceptance of feedback can be overcome. PMID:26457152

  16. Development of an ACP facility

    SciTech Connect

    Gil-Sung You; Won-Myung Choung; Jeong-Hoe Ku; il-Je Cho; Dong-Hak Kook; Kie-Chan Kwon; Eun-Pyo Lee; Ji-Sup Yoon; Seong-Won Park; Won-Kyung Lee

    2007-07-01

    KAERI has been developing an advanced spent fuel conditioning process (ACP). The ACP facility for a process demonstration consists of two air-sealed type hot cells. The safety analysis results showed that the facility was designed safely. The relevant integrated performance tests were also carried out successfully. (authors)

  17. Club Drugs

    MedlinePlus

    ... Rohypnol, ketamine, as well as MDMA (ecstasy) and methamphetamine ( Drug Facts: Club Drugs , National Institute on Drug ... Club Drugs , National Institute on Drug Abuse, 2010). Methamphetamine is a powerfully addictive stimulant associated with serious ...

  18. Global Emergency Medicine Journal Club: A Social Media Discussion About the Outpatient Management of Patients With Spontaneous Pneumothorax by Using Pigtail Catheters.

    PubMed

    Trueger, N Seth; Murray, Heather; Kobner, Scott; Lin, Michelle

    2015-10-01

    Annals of Emergency Medicine collaborated with an educational Web site, Academic Life in Emergency Medicine (ALiEM) to host a public discussion featuring the 2014 Annals article on the outpatient management of patients with a spontaneous pneumothorax by using pigtail catheters. The objective was to curate a 14-day (November 10 to 23, 2014) worldwide academic dialogue among clinicians about the article. Four online facilitators hosted the multimodal discussion on the ALiEM Web site, Twitter, and Google Hangout. Comments across the social media platforms were curated for this report, as framed by 4 preselected questions. Engagement was tracked through Web analytic tools. Blog comments, tweets, and video expert commentary involving the featured article are summarized and reported. The dialogue resulted in 1,023 page views from 347 cities in 49 countries on the ALiEM Web site, 279,027 Twitter impressions, and 88 views of the video interview with experts. This Global Emergency Medicine Journal Club created a virtual community of practice from around the world and identified common themes around the management of spontaneous pneumothorax, which included substantial practice variation in regard to inpatient versus outpatient management, location of chest tube, the use of aspiration, and chest radiography after placement. PMID:26059486

  19. Modified acyl-ACP desaturase

    DOEpatents

    Cahoon, Edgar B.; Shanklin, John; Lindgvist, Ylva; Schneider, Gunter

    1998-01-06

    Disclosed is a methods for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.

  20. Modified Acyl-ACP desaturase

    DOEpatents

    Cahoon, Edgar B.; Shanklin, John; Lindqvist, Ylva; Schneider, Gunter

    1999-03-30

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.

  1. Modified Acyl-ACP desaturase

    DOEpatents

    Cahoon, E.B.; Shanklin, J.; Lindqvist, Y.; Schneider, G.

    1999-03-30

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity. 2 figs.

  2. Modified acyl-ACP desaturase

    DOEpatents

    Cahoon, E.B.; Shanklin, J.; Lindgvist, Y.; Schneider, G.

    1998-01-06

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity. 1 fig.

  3. Star Clubbing

    ERIC Educational Resources Information Center

    Hogan, Maria; Davis, Sarah

    2011-01-01

    Despite the rewards, there are numerous barriers to teachers running clubs: (1) getting weekly fresh activity ideas and resourcing them; (2) the lack of a budget; and (3) shortage of time. With the best will in the world, it is easy to feel that time is already swallowed up with planning and assessment of normal lessons, let alone putting in the…

  4. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM... General § 701.44 Agricultural Conservation Program (ACP) contracts. Contracts for ACP that are, or...

  5. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM... General § 701.44 Agricultural Conservation Program (ACP) contracts. Contracts for ACP that are, or...

  6. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM... General § 701.44 Agricultural Conservation Program (ACP) contracts. Contracts for ACP that are, or...

  7. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM... General § 701.44 Agricultural Conservation Program (ACP) contracts. Contracts for ACP that are, or...

  8. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... regulations for ACP contracts and the ACP program that were contained in the 7 CFR, parts 700 to 899, edition... 7 Agriculture 7 2010-01-01 2010-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM...

  9. Join This Cool Club!

    ERIC Educational Resources Information Center

    Novelli, Joan

    1995-01-01

    Students can study the Arctic by creating Arctic clubs, using modems to communicate with students nationwide who are following International Arctic Project (IAP) explorers. The article describes the IAP, explains how to form a club, and discusses issues that clubs can tackle, for example, pollution, Arctic animals, natural resources, and the…

  10. Software for the ACP (Advanced Computer Program) multiprocessor system

    SciTech Connect

    Biel, J.; Areti, H.; Atac, R.; Cook, A.; Fischler, M.; Gaines, I.; Kaliher, C.; Hance, R.; Husby, D.; Nash, T.

    1987-02-02

    Software has been developed for use with the Fermilab Advanced Computer Program (ACP) multiprocessor system. The software was designed to make a system of a hundred independent node processors as easy to use as a single, powerful CPU. Subroutines have been developed by which a user's host program can send data to and get results from the program running in each of his ACP node processors. Utility programs make it easy to compile and link host and node programs, to debug a node program on an ACP development system, and to submit a debugged program to an ACP production system.

  11. The Book Club Exploded

    ERIC Educational Resources Information Center

    Hoffert, Barbara

    2006-01-01

    One leader, 12 readers, and a few well-thumbed copies of Jane Austen's "Pride and Prejudice." That is all a book club once required, but this is no longer the case. This article describes how the runaway popularity of book clubs has brought with it a whole new set of possibilities. Thematic discussion? A fiction/nonfiction mix? Videoconferencing?…

  12. Multimodal Learning Clubs

    ERIC Educational Resources Information Center

    Casey, Heather

    2012-01-01

    Multimodal learning clubs link principles of motivation and engagement with 21st century technological tools and texts to support content area learning. The author describes how a sixth grade health teacher and his class incorporated multimodal learning clubs into a unit of study on human body systems. The students worked collaboratively online…

  13. Clubbed fingers (image)

    MedlinePlus

    ... is a symptom of disease, often of the heart or lungs which cause chronically low blood levels of oxygen. Diseases which cause malabsorption, such as cystic fibrosis or celiac disease can also cause clubbing.

  14. Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP

    PubMed Central

    Luo, Qixia; Li, Meng; Fu, Huihui; Meng, Qiu; Gao, Haichun

    2016-01-01

    It is established that Escherichia coli β-ketoacyl-ACP synthase (KAS) I (encoded by EcfabB) is the primary, if not exclusive, factor for elongation of the cis-3-decenoyl-ACP (C10:1-ACP) but not effective with C16:1- or longer-chain-ACPs. To test the extent to which these features apply to KAS I proteins in other species, in this study, we examined the physiological role of FabB in Shewanella oneidensis, an excellent model for researching type II fatty acid synthetic (FAS) system and its regulation. We showed that the loss of either FabA (the enzyme that introduces double bond) or FabB, in the absence of DesA which desaturizes C16 and C18 to generate respective C16:1 and C18:1, leads to a UFA auxotroph. However, fatty acid profiles of membrane phospholipid of the fabA and fabB mutants are significantly different, suggesting that FabB participates in steps beyond elongation of C10:1-ACP. Further analyses demonstrated that S. oneidensis FabB differs from EcFabB in that (i) it is not the only enzyme capable of catalyzing elongation of the cis-3-decenoyl-ACP produced by FabA, (ii) it plays a critical role in elongation of C16:1- and longer-chain-ACPs, and (iii) its overproduction is detrimental. PMID:27014246

  15. The ACP (Advanced Computer Program) Branch bus and real-time applications of the ACP multiprocessor system

    SciTech Connect

    Hance, R.; Areti, H.; Atac, R.; Biel, J.; Cook, A.; Fischler, M.; Gaines, I.; Husby, D.; Nash, T.; Zmuda, T.

    1987-05-08

    The ACP Branchbus, a high speed differential bus for data movement in multiprocessing and data acquisition environments, is described. This bus was designed as the central bus in the ACP multiprocessing system. In its full implementation with 16 branches and a bus switch, it will handle data rates of 160 MByte/sec and allow reliable data transmission over inter rack distances. We also summarize applications of the ACP system in experimental data acquisition, triggering and monitoring, with special attention paid to FASTBUS environments.

  16. The Interactions of CPP–ACP with Saliva

    PubMed Central

    Huq, Noorjahan Laila; Myroforidis, Helen; Cross, Keith J.; Stanton, David P.; Veith, Paul D.; Ward, Brent R.; Reynolds, Eric C.

    2016-01-01

    The repair of early dental caries lesions has been demonstrated by the application of the remineralisation technology based on casein phosphopeptide-stabilised amorphous calcium phosphate complexes (CPP–ACP). These complexes consist of an amorphous calcium phosphate mineral phase stabilised and encapsulated by the self-assembly of milk-derived phosphopeptides. During topical application of CPP–ACP complexes in the oral cavity, the CPP encounters the enamel pellicle consisting of salivary proteins and peptides. However the interactions of the CPP with the enamel salivary pellicle are not known. The studies presented here reveal that the predominant peptides of CPP–ACP complexes do interact with specific salivary proteins and peptides of the enamel pellicle, and provide a mechanism by which the CPP–ACP complexes are localised at the tooth surface to promote remineralisation. PMID:27294918

  17. Association between ACP(1) genetic polymorphism and favism.

    PubMed

    Polzonetti, V; Passini, V; Lucarini, N

    2011-01-01

    An association between favism (a hemolytic reaction to consumption of fava beans), glucose-6-phosphate dehydrogenase deficiency (G6PD(-)) and acid phosphatase locus 1 (ACP(1)) phenotypes has been reported; the frequency of carriers of the p(a) and p(c) ACP(1) alleles was found to be significantly higher in G6PD(-) individuals showing favism than in the general population. Here, we investigated the hypothesis that favism is caused by toxic Vicia faba substances, which in some ACP(1) phenotypes cause increased phosphorylation and consequently increased glycolysis, with strong reduction in reduced glutathione production, resulting in hemolysis. It has been demonstrated that ACP(1) f isoforms have physiological functions different from those of s isoforms and are responsible for most of the phosphatase activity, in addition to being less stable in the presence of oxidizing molecules. Thus, the C, CA and A phenotypes, characterized by lower concentrations of f isoforms, could be more susceptible to damage by oxidative events compared to the other phenotypes. To test this hypothesis, the (f+s) enzymatic activity of different ACP(1) phenotypes with and without added V. faba extract was analyzed. Enzymatic activities of ACP(1) A, -CA, -C groups (low activity) and -B, -BA, -CB groups (high activity) were significantly different after addition of V. faba extract. Phenotypes A, CA and C had extremely low enzymatic activity levels, which would lead to low levels of reduced glutathione and bring about erythrocyte lysis. PMID:21644204

  18. It's Time for Art Club

    ERIC Educational Resources Information Center

    Hubbert, Beth

    2007-01-01

    In this article, the author describes how her school's art club works. She relates that the art projects made by students at the art club became permanent fixtures at their school. Because of this incentive, students were very eager to contribute to the art club knowing that their art projects will be permanently displayed for all to enjoy in the…

  19. Math Club Starting in Kindergarten

    ERIC Educational Resources Information Center

    Perry, Ann M.

    2011-01-01

    Starting a math club as early as kindergarten and having a range of grade levels in attendance can be successful. With the help of the older students, the varied age groups are entertained and excited about attending math club. The purpose of the club is to enrich the classroom mathematics curriculum with hands-on activities and to have members…

  20. Substrate recognition by β-ketoacyl-ACP synthases.

    PubMed

    Borgaro, Janine G; Chang, Andrew; Machutta, Carl A; Zhang, Xujie; Tonge, Peter J

    2011-12-13

    β-Ketoacyl-ACP synthase (KAS) enzymes catalyze Claisen condensation reactions in the fatty acid biosynthesis pathway. These reactions follow a ping-pong mechanism in which a donor substrate acylates the active site cysteine residue after which the acyl group is condensed with the malonyl-ACP acceptor substrate to form a β-ketoacyl-ACP. In the priming KASIII enzymes the donor substrate is an acyl-CoA while in the elongating KASI and KASII enzymes the donor is an acyl-ACP. Although the KASIII enzyme in Escherichia coli (ecFabH) is essential, the corresponding enzyme in Mycobacterium tuberculosis (mtFabH) is not, suggesting that the KASI or II enzyme in M. tuberculosis (KasA or KasB, respectively) must be able to accept a CoA donor substrate. Since KasA is essential, the substrate specificity of this KASI enzyme has been explored using substrates based on phosphopantetheine, CoA, ACP, and AcpM peptide mimics. This analysis has been extended to the KASI and KASII enzymes from E. coli (ecFabB and ecFabF) where we show that a 14-residue malonyl-phosphopantetheine peptide can efficiently replace malonyl-ecACP as the acceptor substrate in the ecFabF reaction. While ecFabF is able to catalyze the condensation reaction when CoA is the carrier for both substrates, the KASI enzymes ecFabB and KasA have an absolute requirement for an ACP substrate as the acyl donor. Provided that this requirement is met, variation in the acceptor carrier substrate has little impact on the k(cat)/K(m) for the KASI reaction. For the KASI enzymes we propose that the binding of ecACP (AcpM) results in a conformational change that leads to an open form of the enzyme to which the malonyl acceptor substrate binds. Finally, the substrate inhibition observed when palmitoyl-CoA is the donor substrate for the KasA reaction has implications for the importance of mtFabH in the mycobacterial FASII pathway. PMID:22017312

  1. Composite Golf Clubs

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Babcock & Wilcox Co. under a partnership with Marshall Space Flight Center, produced composite materials, originally from the shuttle program, for improving golf clubs. Company used Marshall Space Flight Center's data summary file summarizing typical processing techniques and mechanical and physical properties of graphite and boron- reinforced composite materials. Reinforced composites provide combination of shaft rigidity and flexibility that provide maximum distance.

  2. The smallest study club.

    PubMed

    Sauget, Earl

    2002-01-01

    A specialist on Guam describes a study club of specialists on the island. Although the number of participants is small in absolute terms, the group's monthly meetings centered around cases serves the functions of stimulating currency and self learning and enhances coordination of complex treatment cases. PMID:12602217

  3. Mode of action of anticancer peptides (ACPs) from amphibian origin.

    PubMed

    Oelkrug, Christopher; Hartke, Martin; Schubert, Andreas

    2015-02-01

    Although cancer belongs to one of the leading causes of death around the world, fortunately studies have shown that tumor cells have various targets that are susceptible to attack. Interestingly, tumor cells are comprised of cellular membranes, which are altered in chemical composition relative to non-neoplastic cells, giving them an increased net negative charge. These altered membranes are ideal targets for antimicrobial peptides (AMPs) shown to have additional tumoricidal properties and, hence, named anticancer peptides (ACPs). Several hundred ACPs have been explored in vitro and in vivo on various types of cancer. Novel anticancer agents are supposed not to cause serious side effects and the formation of multidrug-resistant tumor cells. During the quest for potent ACPs, promising candidates were isolated from skin secretions of amphibians, such as the granular glands of the Chinese brown frog, Rana chensinensis. ACPs have to be selective to cancer cells and should not induce strong immune responses or be cleared from the body rapidly. Several modifications can improve ACPs either by optimizing the primary structure rationally or randomly or even by introducing other chemical modifications. PMID:25667440

  4. Palmitoyl-acyl carrier protein (ACP) thioesterase and the evolutionary origin of plant acyl-ACP thioesterases.

    PubMed Central

    Jones, A; Davies, H M; Voelker, T A

    1995-01-01

    Acyl-acyl carrier protein (ACP) thioesterases play an essential role in chain termination during de novo fatty acid synthesis and in the channeling of carbon flux between the two lipid biosynthesis pathways in plants. We have discovered that there are two distinct but related thioesterase gene classes in higher plants, termed FatA and FatB, whose evolutionary divergence appears to be ancient. FatA encodes the already described 18:1-ACP thioesterase. In contrast, FatB representatives encode thioesterases preferring acyl-ACPs having saturated acyl groups. We unexpectedly obtained a 16:0-ACP thioesterase cDNA from Cuphea hookeriana seed, which accumulate predominantly 8:0 and 10:0. The 16:0 thioesterase transcripts were found in non-seed tissues, and expression in transgenic Brassica napus led to the production of a 16:0-rich oil. We present evidence that this type of FatB gene is ancient and ubiquitous in plants and that specialized plant medium-chain thioesterases have evolved independently from such enzymes several times during angiosperm evolution. Also, the ubiquitous 18:1-ACP thioesterase appears to be a derivative of a 16:0 thioesterase. PMID:7734968

  5. Palmitoyl-acyl carrier protein (ACP) thioesterase and the evolutionary origin of plant acyl-ACP thioesterases.

    PubMed

    Jones, A; Davies, H M; Voelker, T A

    1995-03-01

    Acyl-acyl carrier protein (ACP) thioesterases play an essential role in chain termination during de novo fatty acid synthesis and in the channeling of carbon flux between the two lipid biosynthesis pathways in plants. We have discovered that there are two distinct but related thioesterase gene classes in higher plants, termed FatA and FatB, whose evolutionary divergence appears to be ancient. FatA encodes the already described 18:1-ACP thioesterase. In contrast, FatB representatives encode thioesterases preferring acyl-ACPs having saturated acyl groups. We unexpectedly obtained a 16:0-ACP thioesterase cDNA from Cuphea hookeriana seed, which accumulate predominantly 8:0 and 10:0. The 16:0 thioesterase transcripts were found in non-seed tissues, and expression in transgenic Brassica napus led to the production of a 16:0-rich oil. We present evidence that this type of FatB gene is ancient and ubiquitous in plants and that specialized plant medium-chain thioesterases have evolved independently from such enzymes several times during angiosperm evolution. Also, the ubiquitous 18:1-ACP thioesterase appears to be a derivative of a 16:0 thioesterase.

  6. Memory Golf Clubs

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Memory Corporation's investigation of shape memory effect, stemming from Marshall Space Flight Center contracts to study materials for the space station, has aided in the development of Zeemet, a proprietary, high-damping shape memory alloy for the golf industry. The Nicklaus Golf Company has created a new line of golf clubs using Zeemet inserts. Its superelastic and high damping attributes translate into more spin on the ball, greater control, and a solid feel.

  7. Level up Book Club

    ERIC Educational Resources Information Center

    LaGarde, Jennifer; Winner, Matthew C.

    2012-01-01

    Like all great ideas, Level Up Book Club grew out of a genuine need, the spontaneous firing of a few brain sparks, and the kind of luck that comes from being "in the right place at the right time." By mid-June 2011 the authors were already "bona fide" wonder twins--two educators who, although they'd never met, had stumbled upon each other through…

  8. Methamphetamine Use in Club Subcultures

    PubMed Central

    Kelly, Brian C.; LeClair, Amy; Parsons, Jeffrey T.

    2014-01-01

    In recent decades, methamphetamine developed a peculiar geographic distribution in the United States, with limited diffusion in the Northeast. While use within gay clubs received attention, methamphetamine in club subcultures more broadly remains less clear. Using quantitative and qualitative data, we provide a descriptive assessment of methamphetamine use in club subcultures. Methamphetamine use in club subcultures often has instrumental purposes. The context of initiation into methamphetamine use and its close connection to cocaine shape later patterns of use. Viewing meth solely as a gay party drug misses a significant part of the population and may misguide public health strategies to reduce methamphetamine use in the Northeast. PMID:23848380

  9. A Community-oriented CEOS Atmospheric Composition Portal (ACP)

    NASA Astrophysics Data System (ADS)

    Bernonville, S.; Goussev, O.; Falke, S.; Lindsay, F.; Lynnes, C. S.; Yang, W.; Zhao, P.; Johnson, J.

    2012-04-01

    The Atmospheric Composition Constellation (ACC) and the Workgroup for Information Systems and Services (WGISS) within the Committee on Earth Observation Satellites (CEOS) is developing a portal to support interoperability among the atmospheric composition research and applications communities. The CEOS Atmospheric Composition Portal (ACP) is defining approaches for providing data access, tools and contextual guidance for an international suite of remote sensing datasets. An initial prototype provides access to data services and analysis tools hosted by the World Data Center for Remote Sensing of the Atmosphere (WDC-RSAT), NASA's Goddard Earth Sciences Data and Information Services Center (GES DISC) and DataFed. Distributed access to data is implemented via interoperability standards, including the Open Geospatial Consortium's (OGC) Web Map Service (WMS) and Web Coverage Service (WCS). A fundamental aspect to the design, implementation and evolution of the ACP is community collaboration. The portal is intended as a community resource that is created through collaboration across remotely sensed atmospheric composition data organizations and used by a variety of groups across the climate, air quality, and stratospheric ozone domains. The implementation of interoperability standards in the ACP has involved coordination on identifying the most applicable standards and the definition of community-specific conventions to ensure consistent adoption of standards. This presentation includes an overview of the ACP, its community oriented approach, and use of community-conventions in achieving standards-based interoperability.

  10. Thermal induced intramolecular [2 + 2] cycloaddition of allene-ACPs.

    PubMed

    Chen, Kai; Sun, Run; Xu, Qin; Wei, Yin; Shi, Min

    2013-06-28

    A facile synthetic method for preparation of bicyclo[4.2.0] nitrogen heterocycles has been developed via a thermal induced intramolecular [2 + 2] cycloaddition reaction of allene-ACPs. The DFT calculations indicate that this intramolecular cycloaddition proceeds in a concerted manner and a strained small ring is essential.

  11. Book Clubbing! Successful Book Clubs for Young People

    ERIC Educational Resources Information Center

    Littlejohn, Carol

    2011-01-01

    This practical guide demonstrates how to sponsor a successful, student-led book club for grades K through 12 that is fun, easy-to-implement, and encourages reading. Establishing a book club for children and young people that's self-sustaining and successful long-term is a challenge that this book addresses and conquers. According to recent…

  12. 3-Oxoacyl-[ACP] reductase from oilseed rape (Brassica napus).

    PubMed

    Sheldon, P S; Kekwick, R G; Smith, C G; Sidebottom, C; Slabas, A R

    1992-04-01

    3-Oxoacyl-[ACP] reductase (E.C. 1.1.1.100, alternatively known as beta-ketoacyl-[ACP] reductase), a component of fatty acid synthetase has been purified from seeds of rape by ammonium sulphate fractionation, Procion Red H-E3B chromatography, FPLC gel filtration and high performance hydroxyapatite chromatography. The purified enzyme appears on SDS-PAGE as a number of 20-30 kDa components and has a strong tendency to exist in a dimeric form, particularly when dithiothreitol is not present to reduce disulphide bonds. Cleveland mapping and cross-reactivity with antiserum raised against avocado 3-oxoacyl-[ACP] reductase both indicate that the multiple components have similar primary structures. On gel filtration the enzyme appears to have a molecular mass of 120 kDa suggesting that the native structure is tetrameric. The enzyme has a strong preference for the acetoacetyl ester of acyl carrier protein (Km = 3 microM) over the corresponding esters of the model substrates N-acetyl cysteamine (Km = 35 mM) and CoA (Km = 261 microM). It is inactivated by dilution but this can be partly prevented by the inclusion of NADPH. Using an antiserum prepared against avocado 3-oxoacyl-[ACP] reductase, the enzyme has been visualised inside the plastids of rape embryo and leaf tissues by immunoelectron microscopy. Amino acid sequencing of two peptides prepared by digestion of the purified enzyme with trypsin showed strong similarities with 3-oxoacyl-[ACP] reductase from avocado pear and the Nod G gene product from Rhizobium meliloti.

  13. Specificities of the Acyl-Acyl Carrier Protein (ACP) Thioesterase and Glycerol-3-Phosphate Acyltransferase for Octadecenoyl-ACP Isomers (Identification of a Petroselinoyl-ACP Thioesterase in Umbelliferae).

    PubMed Central

    Dormann, P.; Frentzen, M.; Ohlrogge, J. B.

    1994-01-01

    This study was designed to address the question: How specific for double bond position and conformation are plant enzymes that act on oleoyl-acyl carrier protein (ACP)? Octadecenoyl-ACPs with cis double bonds at positions [delta]6, [delta]7, [delta]8, [delta]9, [delta]10, [delta]11, or [delta]12 and elaidyl (18:1[delta]9trans)-ACP were synthesized and used to characterize the substrate specificity of the acyl-ACP thioesterase and acyl-ACP:sn-glycerol-3-phosphate acyltransferase. The two enzymes were found to be specific for the [delta]9 position of the double bond. The thioesterase was highly specific for the [delta]9 cis conformation, but the transferase was almost equally active with the cis and the trans isomer of 18:1[delta]9-ACP. In plants such as the Umbelliferae species coriander (Coriandrum sativum L.) that accumulate petroselinic acid (18:1[delta]6cis) in their seed triacylglycerols, a high petroselinoyl-ACP thioesterase activity was found in addition to the oleoyl-ACP thioesterase. The two activities could be separated by anion-exchange chromatography, indicating that the petroselinoyl-ACP thioesterase is represented by a distinct polypeptide. PMID:12232130

  14. 4-H Club Goat Guide.

    ERIC Educational Resources Information Center

    Brown, R. Kipp

    This guide provides information for 4-H Club members who have decided on a club goat project. Topics include general information in the following areas: show rules; facilities and equipment (barns/sheds, fences, feeders, water containers, and equipment); selection (structural correctness, muscle, volume and capacity, style and balance, and growth…

  15. Journals Abroad

    ERIC Educational Resources Information Center

    Ando, Shoichi

    1975-01-01

    This article summarizes four journal articles on language teaching appearing in the American pedagogical language journals, "The Modern Language Journal,""English Language Teaching Journal," and "TESOL Quarterly." The purpose is to give an indication of what kinds of articles can be found in journals outside Japan. (Text is in Japanese.) (TL)

  16. The DUDES Club

    PubMed Central

    Gross, Paul A.; Efimoff, Iloradanon; Patrick, Lyana; Josewski, Viviane; Hau, Keith; Lambert, Sandy; Smye, Victoria

    2016-01-01

    Abstract Problem addressed In Canada, there are few health promotion programs for men, particularly programs focused on indigenous and other men marginalized by social and structural inequities. Objective of program To build solidarity and brotherhood among vulnerable men; to promote health through education, dialogue, and health screening clinics; and to help men regain a sense of pride and fulfilment in their lives. Program description The DUDES Club was established in 2010 as a community-based health promotion program for indigenous men in the Downtown Eastside neighbourhood of Vancouver, BC. Between August 2014 and May 2015, 150 men completed an evaluation survey developed using a logic model approach. Responses were analyzed based on the 4 dimensions of the indigenous medicine wheel (mental, physical, emotional, and spiritual). Evaluation results demonstrated high participant satisfaction and positive outcomes across all 4 dimensions of health and well-being: 90.6% of respondents indicated that the DUDES Club program improved their quality of life. Participants who attended meetings more often experienced greater physical, mental, and social benefits (P < .05). Conclusion Findings indicate that this innovative model is effective in promoting the well-being of mainly indigenous men through culturally safe services in an urban community.

  17. Book Clubs. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2010

    2010-01-01

    Book clubs provide a reading framework designed to supplement or organize regular classroom reading instruction for students in grades K-8. This review focuses on "Book Club" (Raphael & McMahon, 1994) and "Literature Circles" (Daniels, 2002), but it uses the general lowercase) term "book clubs" to embrace both "Literature Circles" and "Book Club"…

  18. Computer Club Information Kit for Schools.

    ERIC Educational Resources Information Center

    Association for Educational Data Systems, Washington, DC.

    A computer club can provide a group of high school students with an opportunity to satisfy their curiosity about computers and computer programing. This guide offers suggestions for organizing and running such a club. The objectives of a computer club and the duties of the club's sponsor are outlined. Some activities for the first few meetings are…

  19. 26 CFR 1.401(m)-2 - ACP test.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... determined under § 1.401(m)-2(b)(2)(iv) (as it appeared in the April 1, 2007, edition of 26 CFR part 1). (E... determined under § 1.401(m)-2(b)(2)(vi) (as it appeared in the April 1, 2007, edition of 26 CFR Part 1). If... 26 Internal Revenue 5 2010-04-01 2010-04-01 false ACP test. 1.401(m)-2 Section 1.401(m)-2...

  20. Preliminary calibration of the ACP safeguards neutron counter

    NASA Astrophysics Data System (ADS)

    Lee, T. H.; Kim, H. D.; Yoon, J. S.; Lee, S. Y.; Swinhoe, M.; Menlove, H. O.

    2007-10-01

    The Advanced Spent Fuel Conditioning Process (ACP), a kind of pyroprocess, has been developed at the Korea Atomic Energy Research Institute (KAERI). Since there is no IAEA safeguards criteria for this process, KAERI has developed a neutron coincidence counter to make it possible to perform a material control and accounting (MC&A) for its ACP materials for the purpose of a transparency in the peaceful uses of nuclear materials at KAERI. The test results of the ACP Safeguards Neutron Counter (ASNC) show a satisfactory performance for the Doubles count measurement with a low measurement error for its cylindrical sample cavity. The neutron detection efficiency is about 21% with an error of ±1.32% along the axial direction of the cavity. Using two 252Cf neutron sources, we obtained various parameters for the Singles and Doubles rates for the ASNC. The Singles, Doubles, and Triples rates for a 252Cf point source were obtained by using the MCNPX code and the results for the ft8 cap multiplicity tally option with the values of ɛ, fd, and ft measured with a strong source most closely match the measurement results to within a 1% error. A preliminary calibration curve for the ASNC was generated by using the point model equation relationship between 244Cm and 252Cf and the calibration coefficient for the non-multiplying sample is 2.78×10 5 (Doubles counts/s/g 244Cm). The preliminary calibration curves for the ACP samples were also obtained by using an MCNPX simulation. A neutron multiplication influence on an increase of the Doubles rate for a metal ingot and UO2 powder is clearly observed. These calibration curves will be modified and complemented, when hot calibration samples become available. To verify the validity of this calibration curve, a measurement of spent fuel standards for a known 244Cm mass will be performed in the near future.

  1. Club of Rome

    ScienceCinema

    None

    2016-07-12

    Le Club de Rome s'est fait connaître du grand public par la publication du premier ouvrage "Halte à la croissance" qui a fait l'object d'un débat, il y a 2 ans. Le Prof. Tinbergen a commencé par s'adonner à la physique, il est docteur en physique et très tôt il s'est tourné vers les problèmes sociaux économiques. Il est expert auprès des nombreux gouvernements et organisations internationales et il a vu ses travaux couronnés par le prix Nobel en 1969.

  2. Starting a Planet Protectors Club

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2007

    2007-01-01

    If your mission is to teach children how to reduce, reuse, and recycle waste and create the next generation of Planet Protectors, perhaps leading a Planet Protectors Club is part of your future challenges. You don't have to be an expert in waste reduction and recycling to lead a a Planet Protectors Club. You don't even have to be a teacher. You do…

  3. Developing Preservice Teachers' Knowledge of Science Teaching Through Video Clubs

    NASA Astrophysics Data System (ADS)

    Johnson, Heather J.; Cotterman, Michelle E.

    2015-06-01

    Though an adequate understanding of content is a natural prerequisite of teaching (Carlsen in Journal of Research in Science Teaching 30:471-481, 1993), teachers also need to be able to interpret content in ways that facilitate student learning. How to best support novice teachers in developing and refining their content knowledge for teaching is a crucial and ongoing question for preservice teacher educators. Recently, video clubs are being explored as potential contexts for teacher learning (Barnhart & van Es in Teaching and Teacher Education 45:83-93, 2015; Sherin & Han in Teaching and Teacher Education 20:163-183, 2004). We hypothesized that pairing video clubs with student teaching experiences would provide a forum for preservice teachers to discuss issues relevant to their professional trajectory through exposure to models of peer teaching and opportunities to reflect on practice. In this study, we explored how secondary science preservice teachers used video club to restructure their overall science knowledge into science knowledge for teaching. Our findings suggest that video clubs allowed preservice teachers to access and leverage student thinking and instructional resources to deepen their understanding of science content and trajectories for science learning.

  4. ACP5 (Uteroferrin): phylogeny of an ancient and conserved gene expressed in the endometrium of mammals.

    PubMed

    Padua, Maria B; Lynch, Vincent J; Alvarez, Natalia V; Garthwaite, Mark A; Golos, Thaddeus G; Bazer, Fuller W; Kalkunte, Satyan; Sharma, Surendra; Wagner, Gunter P; Hansen, Peter J

    2012-04-01

    Type 5 acid phosphatase (ACP5; also known as tartrate-resistant acid phosphatase or uteroferrin) is a metalloprotein secreted by the endometrial glandular epithelium of pigs, mares, sheep, and water buffalo. In this paper, we describe the phylogenetic distribution of endometrial expression of ACP5 and demonstrate that endometrial expression arose early in evolution (i.e., before divergence of prototherian and therian mammals ~166 million years ago). To determine expression of ACP5 in the pregnant endometrium, RNA was isolated from rhesus, mouse, rat, dog, sheep, cow, horse, armadillo, opossum, and duck-billed platypus. Results from RT-PCR and RNA-Seq experiments confirmed that ACP5 is expressed in all species examined. ACP5 was also demonstrated immunochemically in endometrium of rhesus, marmoset, sheep, cow, goat, and opossum. Alignment of inferred amino acid sequences shows a high conservation of ACP5 throughout speciation, with species-specific differences most extensive in the N-terminal and C-terminal regions of the protein. Analysis by Selecton indicated that most of the sites in ACP5 are undergoing purifying selection, and no sites undergoing positive selection were found. In conclusion, endometrial expression of ACP5 is a common feature in all orders of mammals and has been subjected to purifying selection. Expression of ACP5 in the uterus predates the divergence of therians and prototherians. ACP5 is an evolutionary conserved gene that likely exerts a common function important for pregnancy in mammals using a wide range of reproductive strategies. PMID:22278982

  5. ACP5 (Uteroferrin): phylogeny of an ancient and conserved gene expressed in the endometrium of mammals.

    PubMed

    Padua, Maria B; Lynch, Vincent J; Alvarez, Natalia V; Garthwaite, Mark A; Golos, Thaddeus G; Bazer, Fuller W; Kalkunte, Satyan; Sharma, Surendra; Wagner, Gunter P; Hansen, Peter J

    2012-04-01

    Type 5 acid phosphatase (ACP5; also known as tartrate-resistant acid phosphatase or uteroferrin) is a metalloprotein secreted by the endometrial glandular epithelium of pigs, mares, sheep, and water buffalo. In this paper, we describe the phylogenetic distribution of endometrial expression of ACP5 and demonstrate that endometrial expression arose early in evolution (i.e., before divergence of prototherian and therian mammals ~166 million years ago). To determine expression of ACP5 in the pregnant endometrium, RNA was isolated from rhesus, mouse, rat, dog, sheep, cow, horse, armadillo, opossum, and duck-billed platypus. Results from RT-PCR and RNA-Seq experiments confirmed that ACP5 is expressed in all species examined. ACP5 was also demonstrated immunochemically in endometrium of rhesus, marmoset, sheep, cow, goat, and opossum. Alignment of inferred amino acid sequences shows a high conservation of ACP5 throughout speciation, with species-specific differences most extensive in the N-terminal and C-terminal regions of the protein. Analysis by Selecton indicated that most of the sites in ACP5 are undergoing purifying selection, and no sites undergoing positive selection were found. In conclusion, endometrial expression of ACP5 is a common feature in all orders of mammals and has been subjected to purifying selection. Expression of ACP5 in the uterus predates the divergence of therians and prototherians. ACP5 is an evolutionary conserved gene that likely exerts a common function important for pregnancy in mammals using a wide range of reproductive strategies.

  6. The Continuous Quality Improvement Book Club: Developing a Book Club to Promote Praxis

    ERIC Educational Resources Information Center

    Lyons, Becky; Ray, Chris

    2014-01-01

    This article poses a model for developing a book club to promote praxis. This model is built upon a basic four step framework for developing book clubs and includes specific recommendations to focus the book club on reflection of theory and how to incorporate it into practice. This model will be used to start a book club examining Continuous…

  7. Starting a Secondary School Maths Club.

    ERIC Educational Resources Information Center

    Cocker, Moira; And Others

    1996-01-01

    Compiles the experiences of four people involved in running math clubs. States that the underlying purpose of all clubs is to promote mathematics as an enjoyable pastime while also stimulating students and enhancing the everyday curriculum. Describes difficulties encountered and their solutions, varieties of clubs, sample math problems, and a book…

  8. Role Calls for Boys & Girls Clubs

    ERIC Educational Resources Information Center

    D'Allesandro, Lou

    2013-01-01

    The New Hampshire Alliance of Boys & Girls Clubs has come a long way since the inception of the state's first Club in Manchester more than 100 years ago. The goal of the Boys & Girls Clubs of America is to provide youth with programs and services that allow them to realize their full potential as productive members of society. State and federal…

  9. Facilitating a midwifery book club.

    PubMed

    Chenery-Morris, Samantha

    2012-03-01

    A midwifery student book club was set up at University Campus Suffolk (UCS) with the aim of engaging students in alternative forms of literature relevant to their studies and to enhance their university experience. The book club was well attended by first and second year midwifery students, but less so by third years. There was evidence of informal student engagement with the lecturer through follow up emails about the meetings. Most of the books reviewed were enjoyed, but the responsibility of suggesting a book for their peers to review was deemed too much by some students.

  10. The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

    PubMed Central

    Van Vranken, Jonathan G; Jeong, Mi-Young; Wei, Peng; Chen, Yu-Chan; Gygi, Steven P; Winge, Dennis R; Rutter, Jared

    2016-01-01

    Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily conserved role in FeS biogenesis. ACP is a stable and essential subunit of the eukaryotic FeS biogenesis complex. In the absence of ACP, the complex is destabilized resulting in a profound depletion of FeS throughout the cell. This role of ACP depends upon its covalently bound 4’-phosphopantetheine (4-PP)-conjugated acyl chain to support maximal cysteine desulfurase activity. Thus, it is likely that ACP is not simply an obligate subunit but also exploits the 4-PP-conjugated acyl chain to coordinate mitochondrial fatty acid and FeS biogenesis. DOI: http://dx.doi.org/10.7554/eLife.17828.001 PMID:27540631

  11. The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis.

    PubMed

    Van Vranken, Jonathan G; Jeong, Mi-Young; Wei, Peng; Chen, Yu-Chan; Gygi, Steven P; Winge, Dennis R; Rutter, Jared

    2016-01-01

    Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily conserved role in FeS biogenesis. ACP is a stable and essential subunit of the eukaryotic FeS biogenesis complex. In the absence of ACP, the complex is destabilized resulting in a profound depletion of FeS throughout the cell. This role of ACP depends upon its covalently bound 4'-phosphopantetheine (4-PP)-conjugated acyl chain to support maximal cysteine desulfurase activity. Thus, it is likely that ACP is not simply an obligate subunit but also exploits the 4-PP-conjugated acyl chain to coordinate mitochondrial fatty acid and FeS biogenesis. PMID:27540631

  12. The No Fuss Library Club

    ERIC Educational Resources Information Center

    Fullner, Sheryl Kindle

    2006-01-01

    When budgets are especially tight, librarians often do not have the spare time for innovation, yet these conditions require the most creativity. This article describes how to set up a once-a-week Library Club that meets during the lunch hour. Since many schools have multiple lunch hours, materials can be set up for two or three lunch times at…

  13. Boys & Girls Clubs of America

    MedlinePlus

    ... of Silicon Valley youth awarded $145,000 in college scholarships, organization’s highest honor representing four million kids and teens MORE» Boys & Girls Clubs of America and the University of Wisconsin-Madison to Provide Full Tuition Scholarships for Multicultural Arts Program Two full-tuition ...

  14. Club Drugs. The DAWN Report.

    ERIC Educational Resources Information Center

    Substance Abuse and Mental Health Services Administration (DHHS/PHS), Rockville, MD. Office of Applied Studies.

    This report was prepared in response to requests from the media, law enforcement, and community leaders for information about club drugs. By being able to utilize statistics from hospital emergency departments and by compiling statistics on drug-related deaths, the Drug Abuse Warning Network (DAWN) is able to alert parents, educators, and others…

  15. Science Club--A Concept

    ERIC Educational Resources Information Center

    Wegner, Claas; Issak, Nicole; Tesch, Katharina; Zehne, Carolin

    2016-01-01

    The following article presents a concept of a science club which was developed by two master's students as a part of their thesis and which has been developed and improved ever since. The extra-curricular concept emphasises pupils' individuality through focusing on problem based leaning, station learning, and mixed age groups. Having joined the…

  16. A Science Club Takes Action

    ERIC Educational Resources Information Center

    LeDee, Olivia; Mosser, Anna; Gamble, Tony; Childs, Greg; Oberhauser, Karen

    2007-01-01

    The after-school science club at Galtier Math, Science, and Technology Elementary Magnet School in St. Paul, Minnesota, learned some valuable lessons when they took newfound knowledge about pollution into their homes. After learning about the effects of various contaminants on health and what informed citizens can do about it, students tested…

  17. HRD Journals.

    ERIC Educational Resources Information Center

    1996

    This document consists of four papers presented during a symposium on human resource development (HRD) journals moderated by Peter W.J. Schramade at the 1996 conference of the Academy of Human Resource Development. "Refereed Journals: The Cornerstone of a Developing Profession" (Gary N. McLean) describes the purpose, format, success, and…

  18. New Journalism.

    ERIC Educational Resources Information Center

    Fishwick, Marshall, Ed.

    This volume contains a selection of articles which examine, critique, and help to define the phenomenon of new journalism. Included are "Popular Culture and the New Journalism" (Marshall Fishwick), "Entrance" (Richard A. Kallan), "How 'New'?" (George A. Hough III), "Journalistic Primitivism" (Everette E. Dennis), "Wherein Lies the Value?" (Michael…

  19. Radio Journalism.

    ERIC Educational Resources Information Center

    Bittner, John R.; Bittner, Denise A.

    This book, a how-to-do-it guide for the novice and the professional alike, deals with several aspects of radio journalism: producing documentaries, preparing and announcing radio news, ethics and responsibility, regulation of radio journalism, and careers. It traces the history and growth of radio news, shows its impact on the public, and…

  20. Boys and Girls: Join the Club

    ERIC Educational Resources Information Center

    D'Allesandro, Lou; Wool, Michael; McKenzie, Mary Alice

    2012-01-01

    Boys & Girls Clubs of America count 4,000 community-based clubs serving more than 4 million young people through membership and community outreach. They provide a safe place to spend time during non-school hours and the summer as an alternative to the streets or being home alone--a place to play, have fun and learn. Boys & Girls Clubs began in New…

  1. Learning and Identity in Overlapping Communities of Practice: Surf Club, School and Sports Clubs

    ERIC Educational Resources Information Center

    Light, Richard; Nash, Melanie

    2006-01-01

    Large numbers of children and young people spend their weekends and holidays engaged in the activities of over 300 surf clubs across Australia each summer. Long term membership in these clubs, beginning from as young as five years of age, forms a significant part of children's and young people's development yet surf clubs have yet to receive…

  2. Club Drug Use in Hispanic College Students

    PubMed Central

    Resor, Michelle R.; Cooper, Theodore V.

    2010-01-01

    Club drug use and correlates were examined among 251 Hispanic college students on the Texas - México border. Participants completed questionnaires on substance use, club drug attitudes and beliefs, sexual risk-taking behaviors, depressive symptoms, and acculturation. One-quarter of participants reported club drug use. Regression analyses demonstrated that frequency and history of lifetime use were consistently associated with more permissive drug attitudes and other substance use but not sexual risk-taking, depression symptoms, or acculturation. Acculturation was negatively associated with frequency of club drug use, yet positively associated with use of other illicit substances. Avenues for future studies are suggested. PMID:20653638

  3. Solar detoxification of wastewater in a novel aerated cascade photoreactor (ACP).

    PubMed

    Xi, W; Geissen, S U; Vogelpohl, A

    2001-01-01

    A newly developed aerated cascade photoreactor (ACP), based on a non-concentrating suspension photoreactor, combines the advantages of a cascade with the increased mass-transfer and the use of oxygen from air as an oxidizing agent in a bubble column. Systematic studies of the limiting hydrodynamic conditions in the ACP and the solid/liquid-separation of the photocatalyst from the treated wastewater have shown that the ACP is technically and commercially attractive. The ACP outperforms the thin-film fixed-bed reactor (TFFBR) with respect to a 3-13 times higher degradation efficiency for the model compound dichloroacetic acid (DCA). The treatment of two biologically pretreated real wastewaters, one from a textile factory and one from car-washing, have been successfully carried out under artificial light and sunlight.

  4. Expression and specificity profile of the major acetate transporter AcpA in Aspergillus nidulans.

    PubMed

    Sá-Pessoa, Joana; Amillis, Sotiris; Casal, Margarida; Diallinas, George

    2015-03-01

    AcpA has been previously characterized as a high-affinity transporter essential for the uptake and use of acetate as sole carbon source in Aspergillus nidulans. Here, we follow the expression profile of AcpA and define its substrate specificity. AcpA-mediated acetate transport is detected from the onset of conidiospore germination, peaks at the time of germ tube emergence, and drops to low basal levels in germlings and young mycelia, where a second acetate transporter is also becoming apparent. AcpA activity also responds to acetate presence in the growth medium, but is not subject to either carbon or nitrogen catabolite repression. Short-chain monocarboxylates (benzoate, formate, butyrate and propionate) inhibit AcpA-mediated acetate transport with apparent inhibition constants (Ki) of 16.89±2.12, 9.25±1.01, 12.06±3.29 and 1.44±0.13mM, respectively. AcpA is also shown not to be directly involved in ammonia export, as proposed for its Saccharomyces cerevisiae homologue Ady2p. In the second part of this work, we search for the unknown acetate transporter expressed in mycelia, and for other transporters that might contribute to acetate uptake. In silico analysis, genetic construction of relevant null mutants, and uptake assays, reveal that the closest AcpA homologue (AN1839), named AcpB, is the 'missing' secondary acetate transporter in mycelia. We also identify two major short-chain carboxylate (lactate, succinate, pyruvate and malate) transporters, named JenA (AN6095) and JenB (AN6703), which however are not involved in acetate uptake. This work establishes a framework for further exploiting acetate and carboxylate transport in filamentous ascomycetes. PMID:25708319

  5. Dimethylformamide as a cryoprotectant for canine semen diluted and frozen in ACP-106C.

    PubMed

    Mota Filho, A C; Teles, C H A; Jucá, R P; Cardoso, J F S; Uchoa, D C; Campello, C C; Silva, A R; Silva, L D M

    2011-10-15

    The objective was to assess the effect of adding various concentrations of dimethylformamide on characteristics of canine semen diluted in powdered coconut water (ACP-106C; ACP Biotecnologia, Fortaleza, CE, Brazil) and frozen at -196°C. Fifteen ejaculates were collected by manual stimulation from five adult Boxer dogs. The sperm-rich fraction was diluted in ACP-106C (ACP Biotecnologia) containing 10% egg yolk and divided into four aliquots. The cryoprotectants used for each aliquot were 6% glycerol (control group; CG) or 2%, 4%, or 6% dimethylformamide (DF2, DF4, and DF6, respectively). After thawing, total motility (mean ± SEM) for CG (58.4 ± 24.6) was higher (P < 0.05) than that of the other groups (2% dimethylformamide, 24.4 ± 12.3; 4% dimethylformamide, 26.5 ± 16.1; and 6% dimethylformamide, 21.7 ± 17.9). Furthermore, there was a greater percentage of fast, average, and slow moving sperm (assessed with computer-aided semen analysis; CASA) in CG in comparison with the other three groups. Therefore, based on concentrations tested in this study, dimethylformamide, together with ACP-106C (ACP Biotecnologia) and 10% egg yolk as a diluent, yielded unsatisfactory in vitro results for freezing canine semen.

  6. Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

    PubMed Central

    Byrd, John C; Harrington, Bonnie; O’Brien, Susan; Jones, Jeffrey A; Schuh, Anna; Devereux, Steve; Chaves, Jorge; Wierda, William G; Awan, Farrukh T; Brown, Jennifer R; Hillmen, Peter; Stephens, Deborah M; Ghia, Paolo; Barrientos, Jacqueline C; Pagel, John M; Woyach, Jennifer; Johnson, Dave; Huang, Jane; Wang, Xiaolin; Lannutti, Brian J; Covey, Todd; Fardis, Maria; McGreivy, Jesse; Hamdy, Ahmed; Rothbaum, Wayne; Izumi, Raquel; Diacovo, Thomas G; Johnson, Amy J; Furman, Richard R

    2016-01-01

    Background Irreversible inhibition of Bruton tyrosine kinase (Btk) by ibrutinib represents a significant therapeutic advance for chronic lymphocytic leukemia (CLL). However, ibrutinib also irreversibly inhibits alternative kinase targets, which potentially compromise its therapeutic index. Acalabrutinib (ACP-196) is a more selective irreversible Btk inhibitor specifically designed to improve upon the safety and efficacy of first generation Btk inhibitors. Methods Sixty-one patients with relapsed CLL were treated in a phase 1–2 multicenter study designed to assess the safety, efficacy, pharmacokinetics and pharmacodynamics of oral acalabrutinib. Patients were continuously treated with acalabrutinib 100 to 400 mg once daily in the dose-escalation portion of the study, and 100 mg twice daily in the expansion portion. Results Patient demographics include a median age of 62 years; median of 3 prior therapies; 31% del(17)(p13.1) and 75% unmutated immunoglobulin heavy chain variable genes. No dose-limiting toxicities occurred. The most common adverse events observed were headache (43%), diarrhea (39%) and increased weight (26%). Most adverse events were Grade 1–2. At a median follow-up of 14.3 months, the best overall response rate was 95%, including 85% partial response, 10% partial response with lymphocytosis and 5% stable disease. In patients with del(17)(p13.1), the best overall response was 100%. No cases of Richter’s transformation and only 1 CLL progression have occurred. Conclusions Acalabrutinib is a highly selective Btk inhibitor that provides effective and well tolerated treatment for patients with relapsed CLL, including those with del(17)(p13.1). PMID:26641137

  7. Caveats of an English Conversation Club.

    ERIC Educational Resources Information Center

    Simpson, JoEllen; Ossa, Carlos E.; Rutter, Frank P.

    1999-01-01

    Describes an English conversation club that was initiated at the Universidad del Valle in Cali, Colombia. Suggests ways in which other university communities can better serve their English-speaking populations by creating a similar English conversation club. (Author/VWL)

  8. What A Booster Club Can Do.

    ERIC Educational Resources Information Center

    Hidinger, George

    This speech was presented at the 1976 American Alliance for Health, Physical Education, and Recreation national convention by the principal of an Iowa high school. It discusses the development and effectiveness of the Jefferson High School Booster Club which was developed by an interested parent and has been quite successful. The club has assisted…

  9. Multicultural Mosaic: A Family Book Club.

    ERIC Educational Resources Information Center

    Dias-Mitchell, Laurie; Harris, Elizabeth

    2001-01-01

    Authors, a library media specialist and a literature/language arts teacher, both recipients of Theodore R. Sizer Fellowships, describe their joint project, "Multicultural Mosaic: A Family Book Club." Their proposal was to strengthen the home-school connection by establishing a book club accessible to all middle and high school students and their…

  10. Healthy Living Initiative: Running/Walking Club

    ERIC Educational Resources Information Center

    Stylianou, Michalis; Kulinna, Pamela Hodges; Kloeppel, Tiffany

    2014-01-01

    This study was grounded in the public health literature and the call for schools to serve as physical activity intervention sites. Its purpose was twofold: (a) to examine the daily distance covered by students in a before-school running/walking club throughout 1 school year and (b) to gain insights on the teachers perspectives of the club.…

  11. Situated Learning in an Australian Surf Club

    ERIC Educational Resources Information Center

    Light, Richard

    2006-01-01

    The article examines learning and identity formation for young people in an Australian surf club. Drawing on Lave and Wenger's notion of situated learning, it identifies how membership in the surf club from an early age involves highly significant and meaningful learning and identity formation, where learning is co-constructed with other members…

  12. STEM Club Participation and STEM Schooling Outcomes

    ERIC Educational Resources Information Center

    Gottfried, Michael A.; Williams, Darryl N.

    2013-01-01

    To develop a more robust understanding of the relationship between non-formal, school-based STEM activities and students' success and persistence in STEM fields, this study evaluates how math club participation influences math GPA and how science club participation influences science GPA. Additionally, this study evaluates how math or science club…

  13. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.

    PubMed

    Maloney, Finn P; Gerwick, Lena; Gerwick, William H; Sherman, David H; Smith, Janet L

    2016-09-13

    Alkyl branching at the β position of a polyketide intermediate is an important variation on canonical polyketide natural product biosynthesis. The branching enzyme, 3-hydroxy-3-methylglutaryl synthase (HMGS), catalyzes the aldol addition of an acyl donor to a β-keto-polyketide intermediate acceptor. HMGS is highly selective for two specialized acyl carrier proteins (ACPs) that deliver the donor and acceptor substrates. The HMGS from the curacin A biosynthetic pathway (CurD) was examined to establish the basis for ACP selectivity. The donor ACP (CurB) had high affinity for the enzyme (Kd = 0.5 μM) and could not be substituted by the acceptor ACP. High-resolution crystal structures of HMGS alone and in complex with its donor ACP reveal a tight interaction that depends on exquisite surface shape and charge complementarity between the proteins. Selectivity is explained by HMGS binding to an unusual surface cleft on the donor ACP, in a manner that would exclude the acceptor ACP. Within the active site, HMGS discriminates between pre- and postreaction states of the donor ACP. The free phosphopantetheine (Ppant) cofactor of ACP occupies a conserved pocket that excludes the acetyl-Ppant substrate. In comparison with HMG-CoA (CoA) synthase, the homologous enzyme from primary metabolism, HMGS has several differences at the active site entrance, including a flexible-loop insertion, which may account for the specificity of one enzyme for substrates delivered by ACP and the other by CoA.

  14. Recovery and cryopreservation of epididymal sperm from agouti (Dasiprocta aguti) using powdered coconut water (ACP-109c) and Tris extenders.

    PubMed

    Silva, M A; Peixoto, G C X; Santos, E A A; Castelo, T S; Oliveira, M F; Silva, A R

    2011-10-01

    The objective was to compare the use of powdered coconut water (ACP-109c; ACP Biotecnologia, Fortaleza, CE, Brazil) and Tris extenders for recovery and cryopreservation of epididymal sperm from agouti. The caudae epididymus and proximal ductus deferens from 10 sexually mature agoutis were subjected to retrograde washing using ACP-109c (ACP Biotecnologia) or Tris. Epididymal sperm were evaluated for motility, vigor, sperm viability, membrane integrity, and morphology. Samples were centrifuged, and extended in the same diluents plus egg yolk (20%) and glycerol (6%), frozen in liquid nitrogen, and subsequently thawed at 37°C for 1 min, followed by re-evaluation of sperm characteristics. The two extenders were similarly efficient for epididymal recovery, with regard to the number and quality of sperm recovered. However, for both extenders, sperm quality decreased (P < 0.05) after centrifugation and dilution. After sperm cryopreservation and thawing, there were (mean ± SEM) 26.5 ± 2.6% motile sperm with 2.6 ± 0.2 vigor in the ACP-109c (ACP Biotecnologia) group, which was significantly better than 9.7 ± 2.6% motile sperm with 1.2 ± 0.3 vigor in Tris. In conclusion, agouti epididymal sperm were successfully recovered using either ACP-109c (ACP Biotecnologia) or Tris extenders; however, ACP-109c (ACP Biotecnologia) was a significantly better extender for processing and cryopreserving these sperm.

  15. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.

    PubMed

    Maloney, Finn P; Gerwick, Lena; Gerwick, William H; Sherman, David H; Smith, Janet L

    2016-09-13

    Alkyl branching at the β position of a polyketide intermediate is an important variation on canonical polyketide natural product biosynthesis. The branching enzyme, 3-hydroxy-3-methylglutaryl synthase (HMGS), catalyzes the aldol addition of an acyl donor to a β-keto-polyketide intermediate acceptor. HMGS is highly selective for two specialized acyl carrier proteins (ACPs) that deliver the donor and acceptor substrates. The HMGS from the curacin A biosynthetic pathway (CurD) was examined to establish the basis for ACP selectivity. The donor ACP (CurB) had high affinity for the enzyme (Kd = 0.5 μM) and could not be substituted by the acceptor ACP. High-resolution crystal structures of HMGS alone and in complex with its donor ACP reveal a tight interaction that depends on exquisite surface shape and charge complementarity between the proteins. Selectivity is explained by HMGS binding to an unusual surface cleft on the donor ACP, in a manner that would exclude the acceptor ACP. Within the active site, HMGS discriminates between pre- and postreaction states of the donor ACP. The free phosphopantetheine (Ppant) cofactor of ACP occupies a conserved pocket that excludes the acetyl-Ppant substrate. In comparison with HMG-CoA (CoA) synthase, the homologous enzyme from primary metabolism, HMGS has several differences at the active site entrance, including a flexible-loop insertion, which may account for the specificity of one enzyme for substrates delivered by ACP and the other by CoA. PMID:27573844

  16. The Drosophila melanogaster seminal fluid protein Acp62F is a protease inhibitor that is toxic upon ectopic expression.

    PubMed

    Lung, Oliver; Tram, Uyen; Finnerty, Casey M; Eipper-Mains, Marcie A; Kalb, John M; Wolfner, Mariana F

    2002-01-01

    Drosophila melanogaster seminal fluid proteins stimulate sperm storage and egg laying in the mated female but also cause a reduction in her life span. We report here that of eight Drosophila seminal fluid proteins (Acps) and one non-Acp tested, only Acp62F is toxic when ectopically expressed. Toxicity to preadult male or female Drosophila occurs upon one exposure, whereas multiple exposures are needed for toxicity to adult female flies. Of the Acp62F received by females during mating, approximately 10% enters the circulatory system while approximately 90% remains in the reproductive tract. We show that in the reproductive tract, Acp62F localizes to the lumen of the uterus and the female's sperm storage organs. Analysis of Acp62F's sequence, and biochemical assays, reveals that it encodes a trypsin inhibitor with sequence and structural similarities to extracellular serine protease inhibitors from the nematode Ascaris. In light of previous results demonstrating entry of Acp62F into the mated female's hemolymph, we propose that Acp62F is a candidate for a molecule to contribute to the Acp-dependent decrease in female life span. We propose that Acp62F's protease inhibitor activity exerts positive protective functions in the mated female's reproductive tract but that entry of a small amount of this protein into the female's hemolymph could contribute to the cost of mating. PMID:11805057

  17. Health promotion profile of youth sports clubs in Finland: club officials' and coaches' perceptions

    PubMed Central

    Kokko, Sami; Kannas, Lasse; Villberg, Jari

    2009-01-01

    SUMMARY The purpose of this article is to examine the current health promotion orientation of youth sports clubs in Finland in view of the standards created previously for the health promoting sports club (HPSC). Ninety-seven youth sports clubs participated, and 273 sports club officials and 240 coaches answered the questionnaires. To describe clubs health promotion orientations, an HPSC index was created. The HPSC index was formulated on sub-indices by factor analysis. The sub-indices were: policy, ideology, practice and environment indexes. The results indicate that youth sports clubs are fairly health promoting in general. On average, the clubs fulfilled 12 standards for HPSC out of 22. Every fourth club was categorized as higher health promoting (≥ 15 fulfilled standards), and every third as lower health promoting (<11 fulfilled standards). The variation between clubs was wide. The clubs that had been recognized as exemplary and hence certified by the Young Finland Association were more likely to recognize health promotion than non-certified clubs (OR = 2.36, p = 0.016). The sports club officials were twice as likely to evaluate their clubs as higher health promoting than the coaches (OR = 2.04, p = 0.041). Under the sub-indices, ideologies were recognized best, others less. These findings indicate that minority of the youth sports clubs have realized health promotion comprehensively as a part of their activities. There is a lot of need for development, especially in the area of health promotion policies and practices. The instruments used proved valid and reliable and can therefore be recommended for international use. PMID:19136676

  18. Interaction between infectious diseases and personality traits: ACP1*C as a potential mediator.

    PubMed

    Napolioni, Valerio; Murray, Damian R; Comings, David E; Peters, Warren R; Gade-Andavolu, Radhika; MacMurray, James

    2014-08-01

    In geographical regions characterized by high pathogen prevalence, it has been shown that human populations tend to be characterized by lower levels of extraversion (E) and openness to experience (OtE). According to the "behavioral immune system" hypothesis, the reduction of extraversion and openness levels represents a behavioral defense against infections. Like the 'classical' immune system, the "behavioral immune system" could also be shaped by its underlying genetic background. Previous studies have shown that the *C allele of the ACP1 gene confers increased susceptibility to infectious/parasitic diseases. We hypothesized that carriers of the ACP1*C allele should likewise be associated with reduced E and OtE. We tested this hypothesis using two samples comprised of 153 students from Southern California (Group 1), and 162 female subjects recruited from an executive health program (Group 2), genotyped for ACP1 polymorphism and evaluated by the NEO Five-Factor Inventory (NEO-FFI). ACP1 was significantly associated with E: we found that carriers of ACP1*C showed reduced scores for E (Group 1: β=-4.263, P=0.027; Group 2: β=-8.315, P=0.003; Group 1+Group 2: β=-5.366, P=0.001). Across groups, ACP1 was only marginally associated with OtE. In conclusion, the present study found that the ACP1*C allele, previously associated with an increased vulnerability to infectious/parasitic diseases may also be able to shape behavioral immune defenses by interaction with the level of E. PMID:24933463

  19. Biomedical journals: keeping up and reading critically.

    PubMed

    Chase, Karen L; DiGiacomo, Ronald F; Van Hoosier, Gerald L

    2006-09-01

    By extrapolation from studies of physicians, knowledge and practice of laboratory animal medicine and science are expected to become progressively more outdated the longer practitioners are out of school. Keeping up with current literature and practice is a challenge that necessitates the use of many different sources of continuing education. Both veterinarians and physicians consistently list journals as the most beneficial source of new information. Accordingly, they must select from the veterinary and biomedical literature articles that report original studies and systematic reviews and recognize and respond to valid new knowledge to improve diagnostic and therapeutic approaches and maintain consistent clinical skills. Other objectives include selecting journals for general information and for information relevant or specific to one's field of research. Lastly, candidates for board certification need to read articles from journals that potentially provide the basis for questions on the examination. 'High-impact' journals should be identified, and articles should be reviewed critically. In a survey of recent candidates for laboratory animal medicine board examination, these journals included Contemporary Topics (now JAALAS), Comparative Medicine, ILAR Journal, and Laboratory Animals. Strategies for coping with the challenge of staying current with the literature include wise use of technology, journal clubs, and consultation with colleagues. A laboratory animal practitioner can become a better scientist and clinician by evaluating the research performed by others. Thorough, critical review of biomedical literature is paramount to these goals.

  20. Ecosystem Journalism

    ERIC Educational Resources Information Center

    Robertson, Amy; Mahlin, Kathryn

    2005-01-01

    If the organisms in a prairie ecosystem created a newspaper, what would it look like? What important news topics of the ecosystem would the organisms want to discuss? Imaginative and enthusiastic third-grade students were busy pondering these questions as they tried their hands at "ecosystem journalism." The class had recently completed a study of…

  1. DEVELOPMENT OF A HOMEMAKER'S CLUB, LARIMER COUNTY, FORT COLLINS, COLORADO.

    ERIC Educational Resources Information Center

    EDGINGTON, ROYAL H.

    THE ORGANIZATION OF A HOMEMAKER'S CLUB FOR MOTHERS UNDER AID TO DEPENDENT CHILDREN WAS PRESENTED. THE CLUB WAS SPONSORED BY THE LARIMER COUNTY DEPARTMENT OF PUBLIC WELFARE. PERSONNEL FROM THE DEPARTMENT ASSISTED IN EVALUATING A PAST FAILURE OF A HOMEMAKER'S CLUB AND IN FORMULATING PLANS FOR A SECOND CLUB. A DISCUSSION OF THE FAILURE OF THE FIRST…

  2. The Sierra Club--A History. Part 2: Conservation

    ERIC Educational Resources Information Center

    Strong, Douglas H.

    1977-01-01

    This second article on Sierra Club history brings the Club into the 1960s. It relates early conservation activities of the club, such as the efforts to save the Hetch Hetchy Valley. The campaign against construction of a dam in Dinosaur National Monument helped establish the club as a national organization. (MA)

  3. [Constructing an ACP Simulation-Situation Communication Training Program for Patients With Chronic Kidney Disease].

    PubMed

    Chen, Jui-O; Lin, Chiu-Chu

    2016-06-01

    The aging population and changing lifestyles have lead to the increased general risk of chronic kidney disease. Taiwan currently has the highest incidence and prevalence of end-stage renal disease (ESRD) of any country or region in the world. Hemodialysis patients must endure comorbidities and face the uncertainties of death. The best way to achieve a good death is for patients to sign advance care planning (ACP). However, the key factors contributing to low ACP signature rates have been the lack of communication skills and related training among medical staffs. This article explores the dilemma of ACP using an example of chronic kidney disease (CKD) and proposes a theory-based approach to develop a theoretical framework for an ACP simulation-situation communication training program that integrates the simulation situation model, PREPARED model, and scaffolding theory. Readers may use this framework to design ACP simulation-situation communication training programs that conform to their own conditions and then test the effectiveness and feasibility of these programs in clinical settings.

  4. [Constructing an ACP Simulation-Situation Communication Training Program for Patients With Chronic Kidney Disease].

    PubMed

    Chen, Jui-O; Lin, Chiu-Chu

    2016-06-01

    The aging population and changing lifestyles have lead to the increased general risk of chronic kidney disease. Taiwan currently has the highest incidence and prevalence of end-stage renal disease (ESRD) of any country or region in the world. Hemodialysis patients must endure comorbidities and face the uncertainties of death. The best way to achieve a good death is for patients to sign advance care planning (ACP). However, the key factors contributing to low ACP signature rates have been the lack of communication skills and related training among medical staffs. This article explores the dilemma of ACP using an example of chronic kidney disease (CKD) and proposes a theory-based approach to develop a theoretical framework for an ACP simulation-situation communication training program that integrates the simulation situation model, PREPARED model, and scaffolding theory. Readers may use this framework to design ACP simulation-situation communication training programs that conform to their own conditions and then test the effectiveness and feasibility of these programs in clinical settings. PMID:27250964

  5. Effect of CPP/ACP on Initial Bioadhesion to Enamel and Dentin In Situ

    PubMed Central

    2014-01-01

    The present in situ study investigated the influence of a preparation containing CPP/ACP (caseinphosphopeptide-amorphous calcium phosphate) (GC Tooth mousse) on initial bacterial colonization of enamel and dentin. Therefore, pellicle formation was performed in situ on bovine enamel and dentin specimens fixed to individual upper jaw splints worn by 8 subjects. After 1 min of pellicle formation GC Tooth mousse was used according to manufacturer's recommendations. Rinses with chlorhexidine served as positive controls. Specimens carried without any rinse served as negative controls. After 8 h overnight exposure of the splints, bacterial colonization was quantified by fluorescence microscopy (DAPI and BacLight live/dead staining). Additionally, the colony forming units (CFU) were determined after desorption. Furthermore, the effects on Streptococcus mutans bacteria were tested in vitro (BacLight). There was no significant impact of CPP/ACP on initial bacterial colonization proved with DAPI and BacLight. Determination of CFU showed statistical significance for CPP/ACP to reduce bacterial adherence on enamel. The in vitro investigation indicated no antimicrobial effects for CPP/ACP on Streptococcus mutans suspension. Under the chosen conditions, CPP/ACP (GC Tooth mousse) had no significant impact on initial biofilm formation on dental hard tissues. The tested preparation cannot be recommended for biofilm management. PMID:25386603

  6. iACP: a sequence-based tool for identifying anticancer peptides

    PubMed Central

    Chen, Wei; Ding, Hui; Feng, Pengmian; Lin, Hao; Chou, Kuo-Chen

    2016-01-01

    Cancer remains a major killer worldwide. Traditional methods of cancer treatment are expensive and have some deleterious side effects on normal cells. Fortunately, the discovery of anticancer peptides (ACPs) has paved a new way for cancer treatment. With the explosive growth of peptide sequences generated in the post genomic age, it is highly desired to develop computational methods for rapidly and effectively identifying ACPs, so as to speed up their application in treating cancer. Here we report a sequence-based predictor called iACP developed by the approach of optimizing the g-gap dipeptide components. It was demonstrated by rigorous cross-validations that the new predictor remarkably outperformed the existing predictors for the same purpose in both overall accuracy and stability. For the convenience of most experimental scientists, a publicly accessible web-server for iACP has been established at http://lin.uestc.edu.cn/server/iACP, by which users can easily obtain their desired results. PMID:26942877

  7. Journal Production and Journal Impact Factors.

    ERIC Educational Resources Information Center

    Rousseau, Ronald; Van Hooydonk, Guido

    1996-01-01

    Describes a direct linear relation between the number of articles in a journal and the journal's impact factor. Hypotheses are presented; theoretical considerations are discussed; and results are described that show exceptions for review journals and translation journals, as well as for journals in mathematics and chemistry. (Author/LRW)

  8. Advanced spent fuel conditioning process (ACP) progress with respect to remote operation and maintenance

    SciTech Connect

    Lee, Hyo Jik; Lee, Jong Kwang; Park, Byung Suk; Yoon, Ji Sup

    2007-07-01

    Korea Atomic Energy Research Institute (KAERI) has been developing an Advanced Spent Fuel Conditioning Process (ACP) to reduce the volume of spent fuel, and the construction of the ACP facility (ACPF) for a demonstration of its technical feasibility has been completed. In 2006 two inactive demonstrations were performed with simulated fuels in the ACPF. Accompanied by process equipment performance tests, its remote operability and maintainability were also tested during that time. Procedures for remote operation tasks are well addressed in this study and evaluated thoroughly. Also, remote maintenance and repair tasks are addressed regarding some important modules with a high priority order. The above remote handling test's results provided a lot of information such as items to be revised to improve the efficiency of the remote handling tasks. This paper deals with the current status of ACP and the progress of remote handling of ACPF. (authors)

  9. Association of the acid phosphatase (ACP1) gene with triglyceride levels in obese women.

    PubMed

    Bottini, Nunzio; MacMurray, James; Peters, Warren; Rostamkhani, Masoud; Comings, David E

    2002-11-01

    The acid phosphatase (ACP1) locus codes for a low molecular weight protein tyrosine phosphatase (LMPTP) that is found ubiquitously in human tissues. The *A allele of the ACP1 gene is associated with lower total enzymatic activity than the *B and *C alleles. An association between the *A allele and extreme values of body-mass-index (BMI) and dyslipidemia has previously been described in several samples of obese subjects from the Italian population. In the present study, we investigated the relationship between ACP1 *A allele genotypes (*A/*A, *A/*B, and *A/*C) and non-*A allele genotypes (*B/*B, *B/*C, and *C/*C) and metabolic variables in 277 Caucasian post-menopausal subjects consisting of 82 non-obese subjects (BMI/=35) subjects. ACP1 genotypes were found to be significantly associated with total cholesterol (pACP1 *A allele may be partially protected against developing the metabolic syndrome. The confirmation of ACP1 as a modifier gene of the metabolic complications could open the door to the prevention of the lethal complications of obesity. PMID:12409270

  10. Stacking of a stearoyl-ACP thioesterase with a dual-silenced palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase in transgenic soybean.

    PubMed

    Park, Hyunwoo; Graef, George; Xu, Yixiang; Tenopir, Patrick; Clemente, Tom E

    2014-10-01

    Soybean (Glycine max (L.) Merr) is valued for both its protein and oil, whose seed is composed of 40% and 20% of each component, respectively. Given its high percentage of polyunsaturated fatty acids, linoleic acid and linolenic acid, soybean oil oxidative stability is relatively poor. Historically food processors have employed a partial hydrogenation process to soybean oil as a means to improve both the oxidative stability and functionality in end-use applications. However, the hydrogenation process leads to the formation of trans-fats, which are associated with negative cardiovascular health. As a means to circumvent the need for the hydrogenation process, genetic approaches are being pursued to improve oil quality in oilseeds. In this regard, we report here on the introduction of the mangosteen (Garcinia mangostana) stearoyl-ACP thioesterase into soybean and the subsequent stacking with an event that is dual-silenced in palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase expression in a seed-specific fashion. Phenotypic analyses on transgenic soybean expressing the mangosteen stearoyl-ACP thioesterase revealed increases in seed stearic acid levels up to 17%. The subsequent stacked with a soybean event silenced in both palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase activity, resulted in a seed lipid phenotype of approximately 11%-19% stearate and approximately 70% oleate. The oil profile created by the stack was maintained for four generations under greenhouse conditions and a fifth generation under a field environment. However, in generation six and seven under field conditions, the oleate levels decreased to 30%-40%, while the stearic level remained elevated.

  11. Florida, National Space Club Embrace Commercial Endeavors

    NASA Video Gallery

    NASA's Commercial Crew Program (CCP) Manager Ed Mango and Florida's Lt. Gov. Jennifer Carroll were guest speakers at the National Space Club Florida Committee's luncheon at the Radisson Resort at t...

  12. The Outing Club: Science without Walls

    ERIC Educational Resources Information Center

    Dawson, Paul Dow; Burks, Timothy

    1975-01-01

    In an attempt to give students an opportunity to strengthen skills that will make them effective group members, authors developed a program, "The Doherty School Outing Club", that stresses group dynamics in an outdoor setting. (Author/RK)

  13. Solar Heating System at a Racquetball Club

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Detailed 93-page report describes Arlington, Virginia racquetball club which obtains heat and hot water for its support area from solar collectors. Report explains modes of operation of system and details of acceptance-test plan.

  14. USGS tethered ACP platforms: New design means more safety and accuracy

    USGS Publications Warehouse

    Morlock, S.E.; Stewart, J.A.; Rehmel, M.S.

    2004-01-01

    The US Geological Survey has developed an innovative tethered platform that supports an Acoustic Current Profiler (ACP) in making stream-flow measurements (use of the term ACP in this article refers to a class of instruments and not a specific brand name or model). The tethered platform reduces the hazards involved in conventional methods of stream-flow measurement. The use of the platform reduces or eliminates time spent by personnel in streams and boats or on bridges and cableway and stream-flow measurement accuracy is increased.

  15. Acyl-ACP Substrate Recognition in Burkholderia mallei BmaI1 Acyl-Homoserine Lactone Synthase

    PubMed Central

    2015-01-01

    The acyl-homoserine lactone (AHL) autoinducer mediated quorum sensing regulates virulence in several pathogenic bacteria. The hallmark of an efficient quorum sensing system relies on the tight specificity in the signal generated by each bacterium. Since AHL signal specificity is derived from the acyl-chain of the acyl-ACP (ACP = acyl carrier protein) substrate, AHL synthase enzymes must recognize and react with the native acyl-ACP with high catalytic efficiency while keeping reaction rates with non-native acyl-ACPs low. The mechanism of acyl-ACP substrate recognition in these enzymes, however, remains elusive. In this study, we investigated differences in catalytic efficiencies for shorter and longer chain acyl-ACP substrates reacting with an octanoyl-homoserine lactone synthase Burkholderia mallei BmaI1. With the exception of two-carbon shorter hexanoyl-ACP, the catalytic efficiencies of butyryl-ACP, decanoyl-ACP, and octanoyl-CoA reacting with BmaI1 decreased by greater than 20-fold compared to the native octanoyl-ACP substrate. Furthermore, we also noticed kinetic cooperativity when BmaI1 reacted with non-native acyl-donor substrates. Our kinetic data suggest that non-native acyl-ACP substrates are unable to form a stable and productive BmaI1·acyl-ACP·SAM ternary complex and are thus effectively discriminated by the enzyme. These results offer insights into the molecular basis of substrate recognition for the BmaI1 enzyme. PMID:25215658

  16. Polyketide β-Branching in Bryostatin Biosynthesis: Identification of Surrogate Acetyl-ACP Donors for BryR, an HMG-ACP Synthase

    PubMed Central

    Buchholz, Tonia J.; Rath, Christopher M.; Lopanik, Nicole B.; Gardner, Noah P.; Håkansson, Kristina; Sherman, David H.

    2010-01-01

    Summary In vitro analysis of natural product biosynthetic gene products isolated from unculturable symbiotic bacteria is necessary to probe the functionalities of these enzymes. Herein, we report the biochemical characterization of BryR, the 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase (HMGS) homolog implicated in β-branching at C13 and C21 of the core ring system from the bryostatin metabolic pathway (Bry). We confirmed the activity of BryR using two complementary methods, radio-SDS PAGE and Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry (FTICR-MS). The activity of BryR depended on pairing of the native acetoacetyl-BryM3 acceptor acyl carrier protein (ACP) with an appropriate donor acetyl-ACP from a heterologous HMGS cassette. Additionally, the ability of BryR to discriminate between various ACPs was assessed using a surface plasmon resonance (SPR)-based protein-protein binding assay. Our data suggest that specificity for a protein-bound acyl group is a distinguishing feature between HMGS homologs found in PKS or PKS/NRPS biosynthetic pathways and those of primary metabolism. These findings reveal an important example of molecular recognition between protein components that are essential for biosynthetic fidelity in natural product assembly and modification. PMID:21035732

  17. Primary digital clubbing associated with palmoplantar keratoderma.

    PubMed

    Barraud-Klenovsek, M M; Lübbe, J; Burg, G

    1997-01-01

    The association of hereditary palmoplantar keratoderma and idiopathic clubbing of the digits in the same patient is uncommon. The differential diagnosis includes the Bureau-Barrière-Thomas syndrome, primary pachydermoperiostosis, Fischer's and Volavsek's syndromes, and palmoplantar keratoderma Vörner. A 30-year-old woman with palmoplantar keratoderma and clubbing of the fingers since the age of 13 years is presented. PMID:9187857

  18. Hong Kong: women's club movement expanding.

    PubMed

    1980-01-01

    2 more women's clubs have been opened by the Family Planning Association of Hong Kong following the success of the 1st such club at Yue Taipo organized in September 1970. The 2nd club is located at the Hing Shing Temporary Housing Area in Kwai Chung and caters to new residents. The 3rd, established January 4, 1980, is located at the Fortune Street Temporary Housing Area in Cheung Sha Wan. The overall aim of these clubs is to give a boost to the quality of family life through organized educational and recreational facilities. Activities at both clubs were initiated by formal opening ceremonies presided over by representatives of the Housing Estates and Family Planning Association. Welcoming wellwishers at each ceremony, Mrs. Peggy Lam, Acting Director of the Family Planning Association of Hong Kong; drew attention to the important contribution made by family planning to the well being of families. It was through the wise planning of their families that parents were provided with ample time and energy for the upbringing of chilren, said Mrs. Lam. The activities of the women's clubs include instruction on traditional women's activities, and talks on sanitation, childrearing, interpersonal relations, nutrition, and permanent contraception. Mrs. Lam felt that the fact that 79% of married women of childbearing age in Hing Shing were practicing family planning was most encouraging.

  19. 76 FR 27253 - Safety Zone; Catawba Island Club Fireworks, Catawba Island Club, Port Clinton, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Catawba Island Club Fireworks, Catawba Island Club, Port Clinton, OH AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast... Clinton, Ohio. This zone is intended to restrict vessels from portions of Lake Erie for the Catawba...

  20. 78 FR 58880 - Safety Zone; Catawba Island Club Wedding Event, Catawba Island Club, Catawba Island, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... DHS Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking TFR... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Catawba Island Club Wedding Event, Catawba Island Club, Catawba Island, OH ACTION: Temporary final rule. SUMMARY: The Coast Guard is...

  1. Introducing an Absolute Cavity Pyrgeometer (ACP) for Improving the Atmospheric Longwave Irradiance Measurement (Poster)

    SciTech Connect

    Reda, I.; Stoffel, T.

    2012-03-01

    Advancing climate change research requires accurate and traceable measurement of the atmospheric longwave irradiance. Current measurement capabilities are limited to an estimated uncertainty of larger than +/- 4 W/m2 using the interim World Infrared Standard Group (WISG). WISG is traceable to the Systeme international d'unites (SI) through blackbody calibrations. An Absolute Cavity Pyrgeometer (ACP) is being developed to measure absolute outdoor longwave irradiance with traceability to SI using the temperature scale (ITS-90) and the sky as the reference source, instead of a blackbody. The ACP was designed by NREL and optically characterized by the National Institute of Standards and Technology (NIST). Under clear-sky and stable conditions, the responsivity of the ACP is determined by lowering the temperature of the cavity and calculating the rate of change of the thermopile output voltage versus the changing net irradiance. The absolute atmospheric longwave irradiance is then calculated with an uncertainty of +/- 3.96 W/m2 with traceability to SI. The measured irradiance by the ACP was compared with the irradiance measured by two pyrgeometers calibrated by the World Radiation Center with traceability to the WISG.

  2. FACADE OF THE CLUB MODERNE, SHOWING THE ORIGINAL CURVED CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACADE OF THE CLUB MODERNE, SHOWING THE ORIGINAL CURVED CORNER PROFILE AND TRI-COLOR CARRERE GLASS FACADE. - Anaconda Historic District, Club Moderne, 801 East Park Avenue, Anaconda, Deer Lodge County, MT

  3. KIND Clubs: A Humane Education Innovation That's Working.

    ERIC Educational Resources Information Center

    Finch, Patty

    1990-01-01

    The Kids in Nature's Defense (KIND) Club and the "adopt" a teacher program are described. The importance of animals and the environment is emphasized. Information on how to start a KIND Club is provided. (KR)

  4. Contextual view to north of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north of Burton Park Club House and Amphitheater, taken from adjacent circular drive (135mm lens) - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  5. Contextual view to northnorthwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north-northwest of Burton Park Club House and Amphitheater (90 mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  6. Contextual view to southwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to southwest of Burton Park Club House and Amphitheater (90mm lens). Pedestals within Amphitheater are supports for bench seating - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  7. High School Political Clubs--A First Amendment Right

    ERIC Educational Resources Information Center

    Levy, Martin R.

    1977-01-01

    The First and Fourteenth Amendments guarantee that high school students may form political clubs. Such clubs should be recognized by the school unless they prevent others from learning, interrupt class, or violate valid school rules. (Author/IRT)

  8. The Fun and Fancy Book Club (In the Classroom).

    ERIC Educational Resources Information Center

    Rosler, Florence

    1989-01-01

    Outlines the procedures for organizing a book club for elementary level students. Describes how a book club motivates children to read and gives them the opportunity to share, enjoy, and exercise their oral communication skills. (MM)

  9. General view, Belair Bath and Tennis Club, Belair at Bowie, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view, Belair Bath and Tennis Club, Belair at Bowie, Maryland, looking west. - Belair Bath and Tennis Club, Southwest corner of Belair Drive and Tulip Grove Drive, Bowie, Prince George's County, MD

  10. Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.

    PubMed

    Kremer, Laurent; Dover, Lynn G; Carrère, Séverine; Nampoothiri, K Madhavan; Lesjean, Sarah; Brown, Alistair K; Brennan, Patrick J; Minnikin, David E; Locht, Camille; Besra, Gurdyal S

    2002-06-01

    Mycolic acids consist of long-chain alpha-alkyl-beta-hydroxy fatty acids that are produced by successive rounds of elongation catalysed by a type II fatty acid synthase (FAS-II). A key feature in the elongation process is the condensation of a two-carbon unit from malonyl-acyl-carrier protein (ACP) to a growing acyl-ACP chain catalysed by a beta-ketoacyl-ACP synthase (Kas). In the present study, we provide evidence that kasA from Mycobacterium tuberculosis encodes an enzyme that elongates in vivo the meromycolate chain, in both Mycobacterium smegmatis and Mycobacterium chelonae. We demonstrate that KasA belongs to the FAS-II system, which utilizes primarily palmitoyl-ACP rather than short-chain acyl-ACP primers. Furthermore, in an in vitro condensing assay using purified recombinant KasA, palmitoyl-AcpM and malonyl-AcpM, KasA was found to express Kas activity. Also, mutated KasA proteins, with mutation of Cys(171), His(311), Lys(340) and His(345) to Ala abrogated the condensation activity of KasA in vitro completely. Finally, purified KasA was highly sensitive to cerulenin, a well-known inhibitor of Kas, which may lead to the development of novel anti-mycobacterial drugs targeting KasA. PMID:12023885

  11. Golf players exhibit changes to grip speed parameters during club release in response to changes in club stiffness.

    PubMed

    Osis, Sean T; Stefanyshyn, Darren J

    2012-02-01

    The influence of golf club stiffness on driving performance is currently unclear, and it is possible that this ambiguity is due in part to golfer adaptation to equipment. The purpose of the current study was to elucidate mechanisms of adaptation to club stiffness, during the golf swing, by employing tendon vibration to distort proprioceptive feedback. Vibration (∼50 Hz, ∼1 mm amplitude) was applied to the upper extremities of 24 golfers using DC motors with eccentric weights. Golfers hit golf balls in a laboratory setting using three clubs of varying shaft stiffness, and club kinematics were recorded using high speed (180 Hz) digital cameras. The results demonstrated significant slowing of the club grip during club release for a high-stiffness shaft with vibration. This suggests that, when proprioceptive feedback is available, players adapt to changes in club stiffness by modifying the release dynamics of the club late in the downswing. PMID:21820748

  12. An Exploration of Recent Club Drug Use among Rave Attendees

    ERIC Educational Resources Information Center

    Yacoubian, George S.; Peters, Ronald J.

    2007-01-01

    Raves are characterized by large numbers of youth dancing for long periods of time and by the use of "club drugs," such as 3, 4-methylenedioxymethamphetamine (MDMA or "ecstasy"). While a small body of research has explored the use of ecstasy and other club drugs (EOCD) among club rave attendees in the United States, we are aware of no studies that…

  13. Evaluation of a Smoking Cessation Club for Young People

    ERIC Educational Resources Information Center

    Jinks, Annette; Linnell, Susan

    2006-01-01

    Purpose: The purpose of the study is to undertake a formative evaluation of a young person's Smokebuster club and to examine how young people's experience of being a club member can be used to inform the club's future development. Design/methodology/approach: After seeking and being granted Local Research Ethics Committee approval to undertake the…

  14. Health Promotion Guidance Activity of Youth Sports Clubs

    ERIC Educational Resources Information Center

    Kokko, Sami; Kannas, Lasse; Villberg, Jari; Ormshaw, Michael

    2011-01-01

    Purpose: This paper aims to clarify the extent to which youth sports clubs guide their coaches to recognise health promotion as a part of the coaching practice. The guidance activity of clubs is seen parallel to internal organisational communication. Design/methodology/approach: A survey of 93 (from 120, 78 per cent) youth sports clubs in Finland…

  15. The 4-H Club Meeting: An Essential Youth Development Strategy

    ERIC Educational Resources Information Center

    Cassels, Alicia; Post, Liz; Nestor, Patrick I.

    2015-01-01

    The club meeting has served as a key delivery method for 4-H programming across the United States throughout its history. A survey of WV 4-H community club members reinforces the body of evidence that the 4-H club meeting is an effective vehicle for delivering positive youth learning opportunities within the umbrella of the Essential Elements of…

  16. Contextual view to northwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to northwest of Burton Park Club House and Amphitheater. Steps lead up from wings of stage area to club house grade level (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  17. Redesigning a Club Structure for the 90's.

    ERIC Educational Resources Information Center

    Merrill, Kurt

    The Penn State Outing Club at Pennsylvania State University redesigned operational procedures to better address fiscal, managerial, and leadership development concerns. The student-run club dissolved its old divisional structure, centralized operations, and split into two branches: club officers and the apprentice-style Wilderness Instructional…

  18. Solution Structure of 4'-Phosphopantetheine - GmACP3 from Geobacter Metallireducens: A Specialized Acyl Carrier Protein with Atypical Structural Features and a Putative Role in Lipopolysaccharide Biosyntheses

    SciTech Connect

    Ramelot, Theresa A.; Smola, Matthew J.; Lee, Hsiau-Wei; Ciccosanti, Colleen; Hamilton, Keith; Acton, Thomas; Xiao, Rong; Everett, John K.; Prestegard, James H.; Montelione, Gaetano; Kennedy, Michael A.

    2011-03-08

    GmACP3 from Geobacter metallireducens is a specialized acyl carrier protein (ACP) whose gene, gmet_2339, is located near genes encoding many proteins involved in lipopolysaccharide (LPS) biosynthesis, indicating a likely function for GmACP3 in LPS production. By overexpression in Escherichia coli, about 50% holo-GmACP3 and 50% apo-GmACP3 were obtained. Apo-GmACP3 exhibited slow precipitation and non-monomeric behavior by 15NNMRrelaxation measurements. Addition of 4'-phosphopantetheine (4'-PP) via enzymatic conversion by E. coli holo-ACP synthase resulted in stable >95% holo-GmACP3 that was characterized as monomeric by 15N relaxation measurements and had no indication of conformational exchange. We have determined a high-resolution solution structure of holo-GmACP3 by standard NMR methods, including refinement with two sets of NH residual dipolar couplings, allowing for a detailed structural analysis of the interactions between 4'-PP and GmACP3. Whereas the overall four helix bundle topology is similar to previously solved ACP structures, this structure has unique characteristics, including an ordered 4'-PP conformation that places the thiol at the entrance to a central hydrophobic cavity near a conserved hydrogen-bonded Trp-His pair. These residues are part of a conservedWDSLxH/N motif found in GmACP3 and its orthologs. The helix locations and the large hydrophobic cavity are more similar tomediumand long-chain acyl-ACPs than to other apo- and holo-ACP structures. Taken together, structural characterization along with bioinformatic analysis of nearby genes suggests that GmACP3 is involved in lipid A acylation, possibly by atypical long-chain hydroxy fatty acids, and potentially is involved in synthesis of secondary metabolites.

  19. Power and control in gay strip clubs.

    PubMed

    DeMarco, Joseph R G

    2007-01-01

    The gay strip club is a place in which more than displays of male beauty take place. The mix of customers, performers, liquor, and nudity results in fascinating dynamics. Of interest in this article are the power relationships and issues of control played out both among and between strippers and customers. Based on extensive participant observation conducted in eight cities and numerous bars/clubs and including more than 150 in-depth interviews, this article concerns just one aspect of the world of male strippers who perform for men. PMID:18019071

  20. Results of First Outdoor Comparison Between Absolute Cavity Pyrgeometer (ACP) and Infrared Integrating Sphere (IRIS) Radiometer at PMOD (Presentation)

    SciTech Connect

    Reda, I.; Grobner, J.; Wacker, S.; Stoffel, T.

    2013-03-01

    The ACP and IRIS are developed to establish a world reference for calibrating pyrgeometers with traceability to SI units. The two radiometers are unwindowed with negligible spectral dependence, and traceable to SI units through the temperature scale (ITS-90). The first outdoor comparison between the two designs was held from January 28 to February 8, 2013 at the Physikalisch-Metorologisches Observatorium Davos (PMOD). The difference between the irradiance measured by ACP and that of IRIS was within 1 W/m2. A difference of 5 W/m2 was observed between the irradiance measured by ACP&IRIS and that of the interim World Infrared Standard Group (WISG).

  1. Journal bearing

    DOEpatents

    Menke, John R.; Boeker, Gilbert F.

    1976-05-11

    1. An improved journal bearing comprising in combination a non-rotatable cylindrical bearing member having a first bearing surface, a rotatable cylindrical bearing member having a confronting second bearing surface having a plurality of bearing elements, a source of lubricant adjacent said bearing elements for supplying lubricant thereto, each bearing element consisting of a pair of elongated relatively shallowly depressed surfaces lying in a cylindrical surface co-axial with the non-depressed surface and diverging from one another in the direction of rotation and obliquely arranged with respect to the axis of rotation of said rotatable member to cause a flow of lubricant longitudinally along said depressed surfaces from their distal ends toward their proximal ends as said bearing members are rotated relative to one another, each depressed surface subtending a radial angle of less than 360.degree., and means for rotating said rotatable bearing member to cause the lubricant to flow across and along said depressed surfaces, the flow of lubricant being impeded by the non-depressed portions of said second bearing surface to cause an increase in the lubricant pressure.

  2. Constitutional Law--State Action--Golden v. Biscayne Bay Yacht Club: Preventing Discrimination by Private Clubs

    ERIC Educational Resources Information Center

    Patrick, Michael W.

    1976-01-01

    Although the Supreme Court has refrained from answering whether the membership policies of private clubs can be attacked on state action grounds, the Fifth Circuit Court of Appeals held in the affirmative in Golden v. Biscayne Bay Yacht Club. It ruled that leasing publicly owned bay bottom land to a yacht club constituted sufficient state…

  3. GUIDE FOR SELF-EXAMINATION AND PLANNING, THE CLUB ANALYSIS PROGRAM OF INDUSTRIAL MANAGEMENT CLUBS OF THE YMCA.

    ERIC Educational Resources Information Center

    MEYER, WILLIAM F.

    THIS GUIDE PROVIDES A QUESTION AND ANSWER METHOD IN WHICH LEADERS OF INDUSTRIAL MANAGEMENT CLUBS (IMC) MAY EVALUATE CLUB PROGRESS AND ACCOMPLISHMENTS. A REPORT OF A NATIONAL STUDY MADE BY GEORGE WILLIAMS COLLEGE ON I.M.C. MEMBERS AND THEIR ATTITUDES TOWARD CLUB PROGRESS IS PROVIDED AS A GUIDE FOR GATHERING INFORMATION. A SMALL CORE STEERING…

  4. Transition metal HE`s - VII ACP. Progress report, August 1971--October 1971

    SciTech Connect

    Clink, G.L.

    1998-12-31

    Physical and physicochemical properties of hexaamminechromium III perchlorate (ACP) were investigated to determine its potentiality for HE and/or HE component application. Physicochemical properties obtained through investigation of isothermally aged ACP under conditions of various system and boundary restrictions (open and closed; 50 and 80 C; 0.65 and 0.85 g/cc) show the material to be substantially stable under these simulated isothermal storage conditions from a standpoint of infrared and DTA thermal pattern behavior and chemical analysis of aged residues. Spark sensitivity was 0.25 joules at 5 kv (by LASL type test) and impact sensitivity was about 23 and 14 cm on sandpaper (12A) and steel (12B), respectively.

  5. Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

    PubMed

    Mdluli, K; Slayden, R A; Zhu, Y; Ramaswamy, S; Pan, X; Mead, D; Crane, D D; Musser, J M; Barry, C E

    1998-06-01

    Although isoniazid (isonicotinic acid hydrazide, INH) is widely used for the treatment of tuberculosis, its molecular target has remained elusive. In response to INH treatment, saturated hexacosanoic acid (C26:0) accumulated on a 12-kilodalton acyl carrier protein (AcpM) that normally carried mycolic acid precursors as long as C50. A protein species purified from INH-treated Mycobacterium tuberculosis was shown to consist of a covalent complex of INH, AcpM, and a beta-ketoacyl acyl carrier protein synthase, KasA. Amino acid-altering mutations in the KasA protein were identified in INH-resistant patient isolates that lacked other mutations associated with resistance to this drug. PMID:9616124

  6. Lights, camera and action: learning necrophilia in a psychiatry movie club.

    PubMed

    Kalra, Gurvinder S

    2013-04-01

    Kissed (1996) is a serious film that portrays the disturbing and taboo issue of necrophilia in a delicate and viewer friendly way. Being a rare paraphilia, it may sometimes be difficult to get necrophilia related literature or even understand this complex behavior. An interested person may have to rely on the few case reports from forensic journals or law books in order to understand what and how necrophiles do what they do! A movie club can be an interesting and novel way to learn various issues in medicine and psychiatry, including necrophilia. This paper discusses the use of this film in academic sessions in order to learn necrophilia.

  7. Effects of the addition of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on mechanical properties of luting and lining glass ionomer cement

    NASA Astrophysics Data System (ADS)

    Heravi, Farzin; Bagheri, Hossein; Rangrazi, Abdolrasoul; Mojtaba Zebarjad, Seyed

    2016-07-01

    Recently, the addition of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into glass ionomer cements (GICs) has attracted interest due to its remineralization of teeth and its antibacterial effects. However, it should be investigated to ensure that the incorporation of CPP-ACP does not have significant adverse effects on its mechanical properties. The purpose of this study was to evaluate the effects of the addition of CPP-ACP on the mechanical properties of luting and lining GIC. The first step was to synthesize the CPP-ACP. Then the CPP-ACP at concentrations of 1%, 1.56% and 2% of CPP-ACP was added into a luting and lining GIC. GIC without CPP-ACP was used as a control group. The results revealed that the incorporation of CPP-ACP up to 1.56%(w/w) increased the flexural strength (29%), diametral tensile strength (36%) and microhardness (18%), followed by a reduction in these mechanical properties at 2%(w/w) CPP-ACP. The wear rate was significantly decreased (23%) in 1.56%(w/w) concentration of CPP-ACP and it was increased in 2%(w/w). Accordingly, the addition of 1.56%(w/w) CPP-ACP into luting and lining GIC had no adverse effect on the mechanical properties of luting and lining GIC and could be used in clinical practice.

  8. Hyaluronic acid auto-crosslinked polymer (ACP): Reaction monitoring, process investigation and hyaluronidase stability.

    PubMed

    Pluda, Stefano; Pavan, Mauro; Galesso, Devis; Guarise, Cristian

    2016-10-01

    Hyaluronic Acid (HA) is a non-sulphated glycosaminoglycan that, despite its high molecular weight, is soluble in water and is not resistant to enzymatic degradation, the latter of which hinders its wider application as a biomedical material. Auto-crosslinked polymer (ACP) gels of HA are fully biocompatible hydrogels that exhibit improved viscoelastic properties and prolonged in vivo residence times compared to the native polymer. Crosslinking is achieved through a base-catalysed reaction consisting of the activation of HA carboxyl groups by 2-chloro-1-methylpyridinium iodide (CMPI) and subsequent nucleophilic acyl substitution by the hydroxyl groups of HA in organic solvent. In this study, a number of ACP hydrogels have been obtained via reactions using varying ratios of CMPI to HA. The crosslinking reaction was monitored by rheological measurements in organic solvents during CMPI addition to the reaction mixture. The ACP intermediates, powders and hydrogels were characterized, helping to elucidate the crosslinking process. A two-step mechanism was proposed to explain the observed trends in viscosity and particle size. Syntheses were carried out by varying the reaction temperature, respectively at 0 °C, 25 °C and 45 °C in N-Methyl-2-Pyrrolidone (NMP), as well as the solvent respectively in NMP, DMSO and DMF at 25 °C. Interestingly, varying these parameters did not substantially affect the degree of crosslinking but likely did influence the intra/inter-molecular crosslinking ratio and, therefore, the viscoelastic properties. A wide range of crosslinking densities was confirmed through ESEM analysis. Finally, a comparative hyaluronidase degradation assay revealed that the ACPs exhibited a higher resistance toward enzymatic cleavage at low elastic modulus compared to other more chemically resistant, crosslinked HAs. These observations demonstrated the importance of crosslinking density of matrix structures on substrate availability. PMID:27442913

  9. The Academic Clubs: Theory to Practice

    ERIC Educational Resources Information Center

    Bicknell, Noel

    2010-01-01

    The Lab School of Washington (LSW) uses a unique approach to teaching social studies and humanities content. As part of its arts-driven lower school program, each child spends 40 minutes a day in dedicated rooms that simulate a specific historical time and place. Called "academic clubs," teachers use these spaces to teach thematic, arts-based,…

  10. Dr. von Braun Visits Huntsville Boys Club

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

  11. Hunt Club Satellite Center Three Part Analysis.

    ERIC Educational Resources Information Center

    Seminole Community Coll., Sanford, FL.

    Consisting primarily of data tables and charts, this report on the Hunt Club Center (HCC) at Seminole Community College (SCC) in Sanford, Florida, presents information on course offerings and full-time equivalency (FTE) production for academic years 1987-88 through 1991-92; HCC area demographics; and student characteristics during fall terms 1990…

  12. Topics for Mathematics Clubs. Second Edition.

    ERIC Educational Resources Information Center

    Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

    One of the main purposes of a mathematics club is to provide the opportunity for students to study exciting topics in mathematics not ordinarily discussed in the classroom. Each of the 10 chapters in this booklet is a collection of related subtopics. Each idea is presented and discussed; bibliographies then suggest in-depth reading. The chapters…

  13. Clubs Reach Urban Middle Level Students.

    ERIC Educational Resources Information Center

    Hale, Rosalind P.

    1993-01-01

    When busing limits number of afternoon activities and students do not seem interested anyway, principals must look for opportunities during day to involve students. One inner-city middle-school principal helped teachers initiate program of morning clubs and assemblies to increase student self-esteem and encourage student and parent involvement…

  14. Making a Computer Club, Making a Community.

    ERIC Educational Resources Information Center

    Gillingham, M.; Youniss, E.

    2000-01-01

    Describes the development of a computer club at an inner city elementary school in Chicago. Discusses the sense of community that grew; parent involvement; scaffold learning; self-control; community service; difficulties in creating a sustainable innovation; and possible future directions. (Contains 11 references.) (LRW)

  15. Radio Clubs of Niger: September, 1972.

    ERIC Educational Resources Information Center

    McAnany, Emile G.

    The Radio Club Association of Niger (ARCN) is a private agency and has been in operation for ten years under the guidance of the radio section of the Ministry of Information. The primary objective of this project is not the assimilation of information but the growth in awareness of their situation by local people. Most of the program therefore…

  16. "PTL Club" Viewer Uses and Gratifications.

    ERIC Educational Resources Information Center

    Abelman, Robert

    1989-01-01

    Examines patterns of television viewing and viewing motivations for the "PTL Club" in light of the recent PTL scandal. Extracts the ritualized user and a modified version (curious consumer) of the instrumental user only. Discusses implications for the future of religious television. (SR)

  17. Operations Course Icebreaker: Campus Club Cupcakes Exercise

    ERIC Educational Resources Information Center

    Snider, Brent; Southin, Nancy

    2016-01-01

    Campus Club Cupcakes is an in-class "introduction to operations management" experiential learning exercise which can be used within minutes of starting the course. After reading the one-page mini case, students are encouraged to meet each other and collaborate to determine if making and selling cupcakes to fellow business students would…

  18. After School Astronomy Clubs: Exploring the universe after hours

    NASA Astrophysics Data System (ADS)

    Mayo, L.; Janney, D.

    2011-10-01

    After School Astronomy clubs are unique in focusing on children in the K-12 grades as opposed to the numerous Amateur Astronomy Clubs within the US and abroad whose membership is largely adult focused. Over the last 12 years, we have identified over 140 clubs that were previously running in isolation, provided them with science and education resources and a means to communicate, created an online community of after School Astronomy Clubs, and facilitated the development of new clubs. Over this time, our model for developing and running these clubs has changed as we gained experience with various target populations, educational settings, and external partners and as best practices have emerged regarding engagement, impact, pedagogy, and sustainability. This talk will highlight these experiences and practices and discuss implications for future development of the After School Astronomy Club program.

  19. Intravaginal artificial insemination in bitches using frozen/thawed semen after dilution in powdered coconut water (ACP-106c).

    PubMed

    Uchoa, D C; Silva, T F P; Mota Filho, A C; Silva, L D M

    2012-12-01

    The aim of this study was to evaluate powdered coconut water extender (ACP-106c; ACP Serviços Tecnológicos Ltda, ACP Biotecnologia, Fortaleza, Ceará, Brazil) as a diluent for freezing dog semen and the fertility after vaginal insemination of semen frozen therein. Ten ejaculates were collected from five dogs, evaluated fresh, diluted in ACP-106c, 10% egg yolk and 6% glycerol, cooled and frozen. In the first phase of the study, straws with frozen semen were thawed and immediately subjected to the same analysis as the fresh semen and, in addition, to Computer-Assisted Semen Analysis (CASA). In phase 2, 10 bitches that had been subjected to natural breeding during a preceding oestrous cycle were vaginally inseminated with thawed semen that had been re-diluted in ACP-106c. After thawing, a mean of 77% sperm motility was obtained through subjective analysis and 77.3% through CASA. Following artificial insemination, a 60% pregnancy rate was observed, resulting in a 50% parturition rate and a mean litter size of 3.4 (SEM 0.6), with 47.1% males and 52.9% females. ACP-106c can be successfully used for freezing canine semen, and vaginal deposition of such semen yields similar pregnancy rates to those reported in other studies.

  20. Acyl-ACP thioesterases from macadamia (Macadamia tetraphylla) nuts: cloning, characterization and their impact on oil composition.

    PubMed

    Moreno-Pérez, Antonio J; Sánchez-García, Alicia; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2011-01-01

    The mechanisms by which macadamia nuts accumulate the unusual palmitoleic and asclepic acyl moieties, which constitute up to 20% of the fatty acids in some varieties, are still unknown. Acyl-acyl carrier protein (ACP) thioesterases (EC 3.1.2.14) are intraplastidial enzymes that terminate the synthesis of fatty acids in plants and that facilitate the export of the acyl moieties to the endoplasmic reticulum where they can be used in the production of glycerolipids. Here, we have investigated the possible role of acyl-ACP thioesterase activity in the composition of macadamia kernel oil. Accordingly, two acyl-ACP thioesterases were cloned from developing macadamia kernels, one of the FatA type and the other of the FatB type. These enzymes were heterologously expressed in Escherichia coli, and the recombinant thioesterases were purified, characterized kinetically and assayed with a variety of substrates, demonstrating the high specificity of macadamia FatA towards 16:1-ACP. Acyl-ACP thioesterase activity was also characterized in crude extracts from two different varieties of macadamia, Cate and Beaumont, which accumulate different amounts of n-7 fatty acids. The impact of acyl-ACP thioesterase activities on the oil composition of these kernels is discussed in the light of these results.

  1. Acyl-ACP thioesterases from macadamia (Macadamia tetraphylla) nuts: cloning, characterization and their impact on oil composition.

    PubMed

    Moreno-Pérez, Antonio J; Sánchez-García, Alicia; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2011-01-01

    The mechanisms by which macadamia nuts accumulate the unusual palmitoleic and asclepic acyl moieties, which constitute up to 20% of the fatty acids in some varieties, are still unknown. Acyl-acyl carrier protein (ACP) thioesterases (EC 3.1.2.14) are intraplastidial enzymes that terminate the synthesis of fatty acids in plants and that facilitate the export of the acyl moieties to the endoplasmic reticulum where they can be used in the production of glycerolipids. Here, we have investigated the possible role of acyl-ACP thioesterase activity in the composition of macadamia kernel oil. Accordingly, two acyl-ACP thioesterases were cloned from developing macadamia kernels, one of the FatA type and the other of the FatB type. These enzymes were heterologously expressed in Escherichia coli, and the recombinant thioesterases were purified, characterized kinetically and assayed with a variety of substrates, demonstrating the high specificity of macadamia FatA towards 16:1-ACP. Acyl-ACP thioesterase activity was also characterized in crude extracts from two different varieties of macadamia, Cate and Beaumont, which accumulate different amounts of n-7 fatty acids. The impact of acyl-ACP thioesterase activities on the oil composition of these kernels is discussed in the light of these results. PMID:21071236

  2. Journalism Education in Canada.

    ERIC Educational Resources Information Center

    MacDonald, Dick; Russell, Catharine

    Twenty-four of the 35 Canadian schools with formal journalism programs responded to a survey conducted to collect data about enrollment, curricula, faculty background in journalism, and the ability of journalism graduates to find jobs in the profession. Highlights of the results are as follows: there are an estimated 3,300 journalism students in…

  3. European journals on microbiology.

    PubMed

    Ronda, C; Vázquez, M

    1997-12-01

    A survey on the scientific journals dealing with microbiology published in Europe has been carried out. Eighteen European countries publish microbiological journals with the United Kingdom. Netherlands and Germany leading in number of journals on this specialty. Most of the European journals on microbiology are published bimonthly (27%), and English is the most common language used (54%). Most of these journals (86%) are included in some database, but only 36 (25%) are indexed in the six databases studied. Out of the 146 journals registered, 71 (49%), published in 11 European countries, are included in the 1995 Journal Citation Reports (ISI, Philadelphia).

  4. East Asian Journal

    NASA Astrophysics Data System (ADS)

    Lee, Hyung Mok

    2005-06-01

    Astronomical research in Asian Pacific region has been growing rapidly in recent years. However, most important papers have been published in well established existing journals in US and Europe because we do not have high impact international journals in this region. I review the current trends of the local journals of East Asian countries and propose to establish a new regional journal by combining domestic journals.

  5. Breakfast Clubs: Starting the Day in a Positive Way

    PubMed Central

    Graham, Pamela Louise; Russo, Riccardo; Defeyter, Margaret Anne

    2015-01-01

    Breakfast clubs are widely promoted as having a beneficial impact on children’s behavior at the start of the school day, which can be conducive to their learning within the classroom. However, the few available studies that have considered the impact of breakfast club attendance on children’s behavior have yielded mixed results and no studies to date have directly observed children’s behavior within the breakfast club setting. Using a combination of real-time observation and filmed breakfast club footage, the aims of the current study were to: (1) devise a set of observational criteria appropriate for use in the breakfast club setting; (2) investigate the occurrence of both positive and negative behaviors. A sample of 30 children aged between 3 and 11 years were recruited from 3, opportunistically sampled primary school breakfast clubs in the North East of England, UK. The behaviors they displayed within the breakfast club setting on two separate days were observed and coded for subsequent analysis. Results of the investigation showed that children’s behavior could be classified into three positive and three negative behavioral categories. Using these categories to code children’s behavior as they engaged in breakfast club showed that children displayed more positive than negative behaviors within the breakfast club setting and this was the case regardless of the type of activity (i.e., quiet or boisterous) children were involved in. Findings are discussed in relation to breakfast club policy, implementation, and evaluation. PMID:26217653

  6. The rich club phenomenon in the classroom

    PubMed Central

    Vaquero, Luis M.; Cebrian, Manuel

    2013-01-01

    We analyse the evolution of the online interactions held by college students and report on novel relationships between social structure and performance. Our results indicate that more frequent and intense social interactions generally imply better score for students engaging in them. We find that these interactions are hosted within a “rich-club”, mediated by persistent interactions among high performing students, which is created during the first weeks of the course. Low performing students try to engage in the club after it has been initially formed, and fail to produce reciprocity in their interactions, displaying more transient interactions and higher social diversity. Furthermore, high performance students exchange information by means of complex information cascades, from which low performing students are selectively excluded. Failure to engage in the rich club eventually decreases these students' communication activity towards the end of the course. PMID:23378908

  7. The effect of CPP-ACP and Nd:YAG laser on the bond strength of softened dentin.

    PubMed

    Kamozaki, Maria Beatriz Beber; Prakki, Anuradha; Perote, Letícia Carvalho Coutinho Costa; Gutierrez, Natalia Cortez; Pagani, Clovis

    2015-01-01

    The purpose of this study was to investigate the effect of CPP-ACP treatment and Nd:YAG laser on microtensile bond strength (µTBS) of softened dentin. Sixty samples were obtained from thirty sound third molars. All samples were submitted to dentin softening procedure, by the immersion of the specimens in 30 mL of Sprite Zero for 30 min. Afterwards, the samples were randomly divided according to the CPP-ACP treatment: CG-Control group; MP-treated with CPP-ACP paste (MI Paste); MPP-treated with CPP-ACP+900 ppm NaF paste (MI Paste Plus). Each group was further divided according to bonding procedure: NL-No laser; L-Laser irradiation after adhesive application and before polymerization. The laser parameters used were 1.4 W, 10 Hz, 140 mJ/pulse, with an optic fiber of 320 µm, generating energy of 174 J/cm(2) per pulse. All samples were restored with Clearfil SE Bond/Filtek Z350 XT. After 24 h, the restored samples were cut into beams (± 1 mm(2) adhesive interface area) and subjected to a µTBS test. Data were analyzed by two-way ANOVA test and Holm-Sidak post-hoc method (α = 0.05). The treatment with CPP-ACP pastes did not significantly affect softened dentin µTBS (p = 0.070). Statistic revealed significant reduction on µTBS values for CG/L, leading to the rejection of the second null hypothesis (p < 0.001). Both CPP-ACP based pastes did not affect µTBS of softened dentin for the adhesive system utilized. The Nd:YAG laser irradiation after application of adhesive system did affect µTBS values of softened dentin samples untreated with CPP-ACP based pastes. PMID:26083086

  8. Identification of Genes Required for Secretion of the Francisella Oxidative Burst-Inhibiting Acid Phosphatase AcpA.

    PubMed

    Hoang, Ky Van; Chen, Carolyn G; Koopman, Jacob; Moshiri, Jasmine; Adcox, Haley E; Gunn, John S

    2016-01-01

    Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing. Our previous studies have shown that after entering its primary cellular host, the macrophage, Francisella immediately suppresses the oxidative burst by secreting a series of acid phosphatases including AcpA-B-C and HapA, thereby evading the innate immune response of the macrophage and enhancing survival and further infection. However, the mechanism of acid phosphatase secretion by Francisella is still unknown. In this study, we screened for genes required for AcpA secretion in Francisella. We initially demonstrated that the known secretion systems, the putative Francisella-pathogenicity island (FPI)-encoded Type VI secretion system and the Type IV pili, do not secrete AcpA. Using random transposon mutagenesis in conjunction with ELISA, Western blotting and acid phosphatase enzymatic assays, a transposon library of 5450 mutants was screened for strains with a minimum 1.5-fold decrease in secreted (culture supernatant) AcpA, but no defect in cytosolic AcpA. Three mutants with decreased supernatant AcpA were identified. The transposon insertion sites of these mutants were revealed by direct genomic sequencing or inverse-PCR and sequencing. One of these mutants has a severe defect in AcpA secretion (at least 85% decrease) and is a predicted hypothetical inner membrane protein. Interestingly, this mutant also affected the secretion of the FPI-encoded protein, VgrG. Thus, this screen identified novel protein secretion factors involved in the subversion of host defenses. PMID:27199935

  9. Identification of Genes Required for Secretion of the Francisella Oxidative Burst-Inhibiting Acid Phosphatase AcpA

    PubMed Central

    Hoang, Ky Van; Chen, Carolyn G.; Koopman, Jacob; Moshiri, Jasmine; Adcox, Haley E.; Gunn, John S.

    2016-01-01

    Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing. Our previous studies have shown that after entering its primary cellular host, the macrophage, Francisella immediately suppresses the oxidative burst by secreting a series of acid phosphatases including AcpA-B-C and HapA, thereby evading the innate immune response of the macrophage and enhancing survival and further infection. However, the mechanism of acid phosphatase secretion by Francisella is still unknown. In this study, we screened for genes required for AcpA secretion in Francisella. We initially demonstrated that the known secretion systems, the putative Francisella-pathogenicity island (FPI)-encoded Type VI secretion system and the Type IV pili, do not secrete AcpA. Using random transposon mutagenesis in conjunction with ELISA, Western blotting and acid phosphatase enzymatic assays, a transposon library of 5450 mutants was screened for strains with a minimum 1.5-fold decrease in secreted (culture supernatant) AcpA, but no defect in cytosolic AcpA. Three mutants with decreased supernatant AcpA were identified. The transposon insertion sites of these mutants were revealed by direct genomic sequencing or inverse-PCR and sequencing. One of these mutants has a severe defect in AcpA secretion (at least 85% decrease) and is a predicted hypothetical inner membrane protein. Interestingly, this mutant also affected the secretion of the FPI-encoded protein, VgrG. Thus, this screen identified novel protein secretion factors involved in the subversion of host defenses. PMID:27199935

  10. Journals and CPD.

    PubMed

    Bryson, David

    2016-01-01

    One of the significant tools for supporting continuing professional development (CPD) is the Institute of Medical Illustrators (IMI) owned publication the Journal of Visual Communication in Medicine. Other journals, for example the Journal of Biological Photography, The British Journal of Photography, British Medical Journal and specialist journals associated with specific areas of medicine, education and illustration, are also helpful. The aim of this paper is to look at journals and CPD together with activities to help you engage with current literature, practice and research. If you look at the examples of CPD activities suggested by both IMI and the Health Professions Council (HPC) one of the recurring themes is the role of journals ( Table 1 ). Journals, alongside conferences, regional and national meetings, are key means of dissemination of research and support for professional development. [Table: see text]. PMID:27253077

  11. Clubs, Pubs, and Models of Mantle Mixing

    NASA Astrophysics Data System (ADS)

    Advocate, Dev L.

    2008-08-01

    Next time you enter a pub, take a moment to ponder your pint and your place and their role in the history of the fluid sciences. Pint by pint, the fluid sciences, the precursors to geodynamics, were developed in the taprooms and clubs of the great nineteenth-century thinkers. They puffed their pipes, sipped their wine and ale, feasted on pies and porridge, satiating and saturating themselves in rising plumes of smoke and steam.

  12. Inhibition and covalent modification of rape seed (Brassica napus) enoyl ACP reductase by phenylglyoxal.

    PubMed

    Cottingham, I R; Austin, A J; Slabas, A R

    1989-05-01

    The NADH-dependent enoyl-ACP reductase from oil seed rape (Brassica napus) was inactivated by treatment with phenylglyoxal, a reagent which specifically modifies arginine residues. The inhibition at various phenylglyoxal concentrations shows pseudo-first-order kinetics, with an apparent second-order rate constant of 14.2 M-1.min-1 for inactivation. The protective ability of several substrates and substrate analogues was investigated in order to ascertain if the inhibition was directed towards the active site of the enzyme. NADH and NAD+ did not protect but acyl carrier protein (ACP) and reduced coenzyme A, along with various derivatives, did protect. 9 microM ACP gave 35% protection from inactivation and 10 mM reduced coenzyme A gave 98% protection. The effectiveness of various subfragments of coenzyme A in protecting against inhibition indicates that the phosphate group is essential for preventing the binding of phenylglyoxal. The idea that phenylglyoxal is inhibiting by binding at the active site is further supported by the observation that the incorporation of 14C-labelled phenylglyoxal is directly related to the loss of activity. Extrapolation of the amount of label incorporated to give total inhibition shows that 4 mol of phenylglyoxal would be incorporated per mol of enzyme. This corresponds to the modification of two arginine side-chains with equal reactiveness towards the reagent. These results are consistent with there being two arginine residues either at the active site of the enzyme or in an environment which is protected from phenylglyoxal by a conformational change induced by coenzyme A binding.

  13. Protective effect of calcium nanophosphate and CPP-ACP agents on enamel erosion.

    PubMed

    Carvalho, Fabíola Galbiatti de; Brasil, Veruska Lima Moura; Silva Filho, Tiago João da; Carlo, Hugo Lemes; Santos, Rogério Lacerda dos; Lima, Bruno Alessandro Silva Guedes de

    2013-01-01

    The aim of this study was to assess the effect of different remineralizing agents on enamel microhardness (KHN) and surface topography after an erosive challenge. Forty-eight human enamel specimens (4 × 4 mm) were randomly assigned to 4 groups: control (no treatment), fluoride varnish, calcium nanophosphate paste and casein phosphopeptide-amorphous calcium phosphate paste (CPP-ACP). Both pastes were applied for 5 minutes, and fluoride varnish, for 24 h. Four daily erosive cycles of 5 minutes of immersion in a cola drink and 2 h in artificial saliva were conducted for 5 days. KHN readings were performed at baseline and after 5 days. The percentage of enamel hardness change (%KHN) was obtained after erosion. The surface topography was evaluated by atomic force microscopy (AFM). The data were tested using ANOVA, Tukey's and paired-T tests (p < 0.05). After an erosive challenge, there was no statistically significant difference between the control (96.8 ± 11.4 KHN / 72.4 ± 3.0%KHN) and the varnish (91.7 ± 14.1 KHN / 73.4 ± 5.5%KHN) groups. The nanophosphate group showed lower enamel hardness loss (187.2 ± 27.9 / 49.0 ± 7.9%KHN), compared with the CPP-ACP group (141.8 ± 16.5 / 60.6 ± 4.0%KHN), and both were statistically different from the varnish and the control groups. AFM images showed a rough surface for the control and the varnish groups, a non-homogeneous layer with globular irregularities for CPP-ACP, and a thick homogeneous layer for the nanophosphate group. None of the agents provided protection against the development of erosion; however, nanophosphate paste was able to reduce enamel surface softening after the erosive challenge.

  14. Combining CPP-ACP with fluoride: a synergistic remineralization potential of artificially demineralized enamel or not?

    NASA Astrophysics Data System (ADS)

    El-Sayad, I. I.; Sakr, A. K.; Badr, Y. A.

    2008-08-01

    Background and objective: Minimal intervention dentistry (MID) calls for early detection and remineralization of initial demineralization. Laser fluorescence is efficient in detecting changes in mineral tooth content. Recaldent is a product of casein phosphopeptide-amorphous calcium phosphate (CPP- ACP) which delivers calcium and phosphate ions to enamel. A new product which also contains fluoride is launched in United States. The remineralizing potential of CPP- ACP per se, or when combined with 0.22% Fl supplied in an oral care gel on artificially demineralised enamel using laser fluorescence was investigated. Methods: Fifteen sound human molars were selected. Mesial surfaces were tested using He-Cd laser beam at 441.5nm with 18mW power as excitation source on a suitable set-up based on Spex 750 M monochromator provided with PMT for detection of collected auto-fluorescence from sound enamel. Mesial surfaces were subjected to demineralization for ten days. The spectra from demineralized enamel were measured. Teeth were then divided according to the remineralizing regimen into three groups: group I recaldent per se, group II recaldent combined with fluoride gel and group III artificial saliva as a positive control. After following these protocols for three weeks, the spectra from remineralized enamel from the three groups were measured. The spectra of enamel auto-fluorescence were recorded and normalized to peak intensity at about 540 nm to compare between spectra from sound, demineralized and remineralized enamel surfaces. Results: A slight red shift was noticed in spectra from demineralized enamel, while a blue shift may occur in remineralized enamel. Group II showed the highest remineralizing potential. Conclusions: Combining fluoride with CPP-ACP had a synergistic effect on enamel remineralization. In addition, laser auto-fluorescence is an accurate technique for assessment of changes in tooth enamel minerals.

  15. Development of the ACP safeguards neutron counter for PWR spent fuel rods

    NASA Astrophysics Data System (ADS)

    Lee, Tae-Hoon; Menlove, Howard O.; Lee, Sang-Yoon; Kim, Ho-Dong

    2008-04-01

    An advanced neutron multiplicity counter has been developed for measuring spent fuel in the Advanced spent fuel Conditioning Process (ACP) at the Korea Atomic Energy Research Institute (KAERI). The counter uses passive neutron multiplicity counting to measure the 244Cm content in spent fuel. The input to the ACP process is spent fuel from pressurized water reactors (PWRs), and the high intensity of the gamma-ray exposure from spent fuel requires a careful design of the counter to measure the neutrons without gamma-ray interference. The nuclear safeguards for the ACP facility requires the measurement of the spent fuel input to the process and the Cm/Pu ratio for the plutonium mass accounting. This paper describes the first neutron counter that has been used to measure the neutron multiplicity distribution from spent fuel rods. Using multiple samples of PWR spent fuel rod-cuts, the singles (S), doubles (D), and triples (T) rates of the neutron distribution for the 244Cm nuclide were measured and calibration curves were produced. MCNPX code simulations were also performed to obtain the three counting rates and to compare them with the measurement results. The neutron source term was evaluated by using the ORIGEN-ARP code. The results showed systematic difference of 21-24% in the calibration graphs between the measured and simulation results. A possible source of the difference is that the burnup codes have a 244Cm uncertainty greater than ±15% and it would be systematic for all of the calibration samples. The S/D and D/T ratios are almost constant with an increment of the 244Cm mass, and this indicates that the bias is in the 244Cm neutron source calculation using the ORIGEN-ARP source code. The graphs of S/D and D/T ratios show excellent agreement between measurement and MCNPX simulation results.

  16. The Sierra Club and immigration policy: a critique.

    PubMed

    Clarke, Alice L

    2001-03-01

    In 1998, the Sierra Club membership voted in a contentious referendum to refrain from including restriction of U.S. immigration as part of its official club population policy. Club proponents of immigration reduction had declared the problem was simply the environmental impact of greater numbers of people; however, they failed to distinguish themselves from groups with much broader immigration-reduction agendas, leaving themselves open to charges of racism. The club faction calling for the exclusion of immigration issues from the policy, on the other hand, failed to acknowledge the demographic reality of the contribution of immigration (30%) to the growth of the U.S. population. As a result, current club policy is not credible, as it calls for a reduction in the U.S. population but ignores immigration. The Sierra Club's complex organi- zational structure and open, democratic political process make it particularly vulnerable to internal conflict during periods of changing perspectives within the organization.

  17. The Fuel Cell Powered Club Car Carryall

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2005-01-01

    The NASA Glenn Research Center initiated development of the Fuel Cell Powered Club Car Carryall as a way to reduce pollution in industrial settings, reduce fossil fuel consumption and reduce operating costs for transportation systems. The Club Car Carryall provides an inexpensive approach to advance the state of the art in electric vehicle technology in a practical application. The project transfers space technology to terrestrial use via non-traditional partners, and provides power system data valuable for future aeronautics and space applications. The work was done under the Hybrid Power Management (HPM) Program. The Carryall is a state of the art, dedicated, electric utility vehicle. Hydrogen powered proton exchange membrane (PEM) fuel cells are the primary power source. Ultracapacitors were used for energy storage as long life, maintenance free operation, and excellent low temperature performance is essential. Metal hydride hydrogen storage was used to store hydrogen in a safe and efficient low-pressure solid form. The report concludes that the Fuel Cell Powered Club Car Carryall can provide excellent performance, and that the implementation of fuel cells in conjunction with ultracapacitors in the power system can provide significant reliability and performance improvements.

  18. Acyl-ACP thioesterases from Camelina sativa: cloning, enzymatic characterization and implication in seed oil fatty acid composition.

    PubMed

    Rodríguez-Rodríguez, Manuel Fernando; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2014-11-01

    Acyl-acyl carrier protein (ACP) thioesterases are intraplastidial enzymes that terminate de novo fatty acid biosynthesis in the plastids of higher plants by hydrolyzing the thioester bond between ACP and the fatty acid synthesized. Free fatty acids are then esterified with coenzyme A prior to being incorporated into the glycerolipids synthesized through the eukaryotic pathway. Acyl-ACP thioesterases belong to the TE14 family of thioester-active enzymes and can be classified as FatAs and FatBs, which differ in their amino acid sequence and substrate specificity. Here, the FatA and FatB thioesterases from Camelina sativa seeds, a crop of interest in plant biotechnology, were cloned, sequenced and characterized. The mature proteins encoded by these genes were characterized biochemically after they were heterologously expressed in Escherichia coli and purified. C. sativa contained three different alleles of both the FatA and FatB genes. These genes were expressed most strongly in expanding tissues in which lipids are very actively synthesized, such as developing seed endosperm. The CsFatA enzyme displayed high catalytic efficiency on oleoyl-ACP and CsFatB acted efficiently on palmitoyl-ACP. The contribution of these two enzymes to the synthesis of C. sativa oil was discussed in the light of these results.

  19. Short-term storage of canine preantral ovarian follicles using a powdered coconut water (ACP)-based medium.

    PubMed

    Lima, G L; Costa, L L M; Cavalcanti, D M L P; Rodrigues, C M F; Freire, F A M; Fontenele-Neto, J D; Silva, A R

    2010-07-01

    The objective was to investigate the use of powdered coconut water (ACP)-based medium for short-term preservation of canine preantral follicles. Pairs of ovaries from mongrel bitches (n=9) were divided into fragments. One ovarian fragment, treated as a fresh control, was immediately fixed for histological analysis, whereas the other six ovarian fragments were stored either in phosphate-buffered saline (PBS; control group) or ACP medium in isothermal Styrofoam boxes containing biological ice packs. The boxes were sealed and opened only after 12, 24, or 36h. After opening each box, the ovarian fragments were submitted to histological analysis. In total, 12,302 preantral follicles were evaluated, with 64.5% primordial, 33.3% primary, and 2.3% secondary follicles. There were multiple oocytes in 1.3% of the follicles analyzed. At 24h, ACP was more efficient in preserving follicular morphology than PBS (P<0.05). Compared with the fresh control group, a significant reduction in the percentage of morphologically normal ovarian follicles was observed for PBS, starting at 24h; however, the decline started only at 36h for the ACP medium. During the experiment, the temperature inside the isothermal boxes increased from 3 to 9 degrees C (P<0.05), despite a constant room temperature. In conclusion, powdered coconut water (ACP) was an appropriate medium for short-term storage of canine preantral ovarian follicles.

  20. Short-term storage of canine preantral ovarian follicles using a powdered coconut water (ACP)-based medium.

    PubMed

    Lima, G L; Costa, L L M; Cavalcanti, D M L P; Rodrigues, C M F; Freire, F A M; Fontenele-Neto, J D; Silva, A R

    2010-07-01

    The objective was to investigate the use of powdered coconut water (ACP)-based medium for short-term preservation of canine preantral follicles. Pairs of ovaries from mongrel bitches (n=9) were divided into fragments. One ovarian fragment, treated as a fresh control, was immediately fixed for histological analysis, whereas the other six ovarian fragments were stored either in phosphate-buffered saline (PBS; control group) or ACP medium in isothermal Styrofoam boxes containing biological ice packs. The boxes were sealed and opened only after 12, 24, or 36h. After opening each box, the ovarian fragments were submitted to histological analysis. In total, 12,302 preantral follicles were evaluated, with 64.5% primordial, 33.3% primary, and 2.3% secondary follicles. There were multiple oocytes in 1.3% of the follicles analyzed. At 24h, ACP was more efficient in preserving follicular morphology than PBS (P<0.05). Compared with the fresh control group, a significant reduction in the percentage of morphologically normal ovarian follicles was observed for PBS, starting at 24h; however, the decline started only at 36h for the ACP medium. During the experiment, the temperature inside the isothermal boxes increased from 3 to 9 degrees C (P<0.05), despite a constant room temperature. In conclusion, powdered coconut water (ACP) was an appropriate medium for short-term storage of canine preantral ovarian follicles. PMID:20207405

  1. Isolation and characterization of a cDNA from Cuphea lanceolata encoding a beta-ketoacyl-ACP reductase.

    PubMed

    Klein, B; Pawlowski, K; Höricke-Grandpierre, C; Schell, J; Töpfer, R

    1992-05-01

    A cDNA encoding beta-ketoacyl-ACP reductase (EC 1.1.1.100), an integral part of the fatty acid synthase type II, was cloned from Cuphea lanceolata. This cDNA of 1276 bp codes for a polypeptide of 320 amino acids with 63 N-terminal residues presumably representing a transit peptide and 257 residues corresponding to the mature protein of 27 kDa. The encoded protein shows strong homology with the amino-terminal sequence and two tryptic peptides from avocado mesocarp beta-ketoacyl-ACP reductase, and its total amino acid composition is highly similar to those of the beta-ketoacyl-ACP reductases of avocado and spinach. Amino acid sequence homologies to polyketide synthase, beta-ketoreductases and short-chain alcohol dehydrogenases are discussed. An engineered fusion protein lacking most of the transit peptide, which was produced in Escherichia coli, was isolated and proved to possess beta-ketoacyl-ACP reductase activity. Hybridization studies revealed that in C. lanceolata beta-ketoacyl-ACP reductase is encoded by a small family of at least two genes and that members of this family are expressed in roots, leaves, flowers and seeds.

  2. Has Communication Explained Journalism?

    ERIC Educational Resources Information Center

    Zelizer, Barbie

    1993-01-01

    Argues for a more interdisciplinary approach to journalism scholarship to provide a fuller account of media power. Considers briefly the notions of performance, narrative, ritual, and interpretive community as alternative frames through which to consider journalism. (SR)

  3. [Fourcroy and pharmaceutical journals].

    PubMed

    Bonnemain, Bruno

    2011-04-01

    Cadet de Gassicourt wrote a brief Eloge of Fourcroy in January 1810 as he died in December of 1809. Fourcroy had a major role concerning the new ideas on the place of pharmacy at the beginning of the 19th century. Fourcroy has had a key influence for the start of several pharmaceutical journals that wanted to emphasize the link between the new chemistry and pharmacy. None of these journals created with him will survive and one has to wait for 1909 to see the creation, without Fourcroy, of a new pharmaceutical journal, the "Journal de Pharmacie" that will become "Journal de Pharmacie et des Sciences accessoires", then "Journal de Pharmacie et de Chimie", before taking the name of"Annales Pharmaceutiques Françaises", the present official journal of the French Academy of Pharmacy. In spite of the essential role of Fourcroy at the start of pharmaceutical journals, Cadet did not even mention it in his Eloge of 1810.

  4. Scientific Journalism in Armenia

    NASA Astrophysics Data System (ADS)

    Farmanyan, S. V.; Mickaelian, A. M.

    2015-07-01

    In the present study, the problems of scientific journalism and activities of Armenian science journalists are presented. Scientific journalism in the world, forms of its activities, Armenian Astronomical Society (ArAS) press-releases and their subjects, ArAS website "Mass Media News" section, annual and monthly calendars of astronomical events, and "Astghagitak" online journal are described. Most interesting astronomical subjects involved in scientific journalism, reasons for non-satisfactory science outreach and possible solutions are discussed.

  5. The β-ketoacyl-ACP synthase from Mycobacterium tuberculosis as potential drug targets.

    PubMed

    Singh, V; Mani, I; Chaudhary, D K; Somvanshi, P

    2011-01-01

    The continuous preventive measures and control of tuberculosis are often hampered by re-emergence of multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis. A novel drug approach is desperately needed to combat the global threat posed by MDR strains. In spite of current advancement in biological techniques viz. microarray and proteomics data for tuberculosis, no such potent drug has been developed in the past decades yet. Therefore, mycolic acid is an essential constituent which is involved in the formation of cell wall of Mycobacterium species. The biosynthesis of mycolic acid is involved in two fatty acid synthase systems, the multifunctional polypeptide fatty acid synthase I (FASI) which performs de novo fatty acid synthesis and dissociate FASII system. FASII system consists of monofunctional enzymes and acyl carrier protein (ACP), elongating FASI products to long chain mycolic acid precursor. In this review, the β-ketoacyl-ACP synthases (fadH, kasA and kasB) are distinct and play a vital role in mycolic acid synthesis, cell wall synthesis, biofilm formation and also pathogenesis. On the basis of substantial observation we suggest that these enzymes may be used as promising and attractive targets for novel anti-TB drugs designing and discovery. PMID:21370994

  6. Kids Club: A School-Age Program Guide for Directors.

    ERIC Educational Resources Information Center

    Sisson, Linda G.

    This handbook for administrators of school-age day care programs offers guidelines on implementing Kids Club programs. Kids Clubs coordinate family and public school resources to meet elementary children's needs for adult supervision and guidance when the children are not in school and their parents are at work. The handbook consists of seven…

  7. Tips for Organizing an Educational Agricultural Commodity Trading Club

    ERIC Educational Resources Information Center

    Yost, John

    2011-01-01

    Educational commodity marketing clubs have been an effective tool for producers to develop their grain and livestock marketing skills. These groups are further enhanced when the participants engage in "actual trading" versus "paper trading" techniques. When a club chooses to try actual trading, it becomes more complicated than pooling monies…

  8. Online Book Clubs: Bridges between Old and New Literacies Practices

    ERIC Educational Resources Information Center

    Scharber, Cassandra

    2009-01-01

    In this Digital Literacies column, online book clubs are offered as one example of how to effectively bridge old and new literacy practices. These Internet-based book clubs capitalize on children's interest in new literacy practices while complementing, and hopefully encouraging, traditional reading practices. Examples from online book clubs…

  9. Stalemate: Girls and a Mixed-Gender Chess Club.

    ERIC Educational Resources Information Center

    Galitis, Ingrid

    2002-01-01

    Observed and conducted discussions with female members of an elementary-level, mixed-gender, Australian chess club to investigate why girls left and boys came to dominate the club. Results indicated that both home values and schooling transmitted and reinforced inequalities between the sexes, though in more subtle and less overt forms than in the…

  10. School Nurse Book Clubs: An Innovative Strategy for Lifelong Learning

    ERIC Educational Resources Information Center

    Greenawald, Deborah A.; Adams, Theresa M.

    2008-01-01

    Recognizing the ongoing need for continuing education for school nurses, the authors discuss the use of school nurse book clubs as an innovative lifelong-learning strategy. Current research supports the use of literature in nursing education. This article discusses the benefits of book club participation for school nurses and includes suggested…

  11. Learning Masculinities in a Japanese High School Rugby Club

    ERIC Educational Resources Information Center

    Light, Richard

    2008-01-01

    This paper draws on research conducted on a Tokyo high school rugby club to explore diversity in the masculinities formed through membership in the club. Based on the premise that particular forms of masculinity are expressed and learnt through ways of playing (game style) and the attendant regimes of training, it examines the expression and…

  12. Teaching the Women's Club Movement in United States History.

    ERIC Educational Resources Information Center

    Woyshner, Christine

    2002-01-01

    Focuses on teaching a U.S. history course to secondary school students about the women's club movement which began in the last quarter of the nineteenth century. Explores five key topic areas involving theoretical frameworks, community activities of the women, and skill development due to club involvement. (CMK)

  13. Read Across Texas! 2002 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Edgmon, Missy; Ferate-Soto, Paolo; Foley, Lelana; Hager, Tina; Heard, Adriana; Ingham, Donna; Lopez, Nohemi; McMahon, Dorothy; Meyer, Sally; Parrish, Leila; Rodriguez-Gibbs, Josefina; Moreyra-Torres, Maricela; Travis, Gayle; Welch, Willy

    The goal of the Texas Reading Club is to encourage the children of Texas to become library users and lifelong readers. This manual was created for the 2002 Texas Reading Club, a program of the Texas State Library and Archives Commission. The theme, "Read Across Texas!" invites children to explore the history, geography, and culture of Texas…

  14. Practice What You Teach: Writers' Lunch Club in First Grade

    ERIC Educational Resources Information Center

    McCarry, Beth; Greenwood, Scott

    2009-01-01

    McCarry, a first grade teacher, formed a voluntary writing group, Writers' Lunch Club, that met the developmental and individual needs of children and inspired enthusiasm and writing success. In the article, she explains the guidelines, compares the club's writing strategies with those in the classroom, and lists tips and benefits.

  15. Contextual view to northwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to northwest of Burton Park Club House and Amphitheater. Gable-roofed building at right is barn housing maintenance equipment for the park. Adobe wall with pilasters forms backdrop for amphitheater stage (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  16. Contextual view to northnorthwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north-northwest of Burton Park Club House and Amphitheater (90 mm lens). View taken from top of steps visible in previous photo. - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  17. After-Hours Science: Teaching Science with a Club.

    ERIC Educational Resources Information Center

    Dyreng, Ivan

    1984-01-01

    Describes Salt Lake City's (Utah) East High School science club, recognized by the National Science Teachers Association's Search for Excellence in Science Education project as an outstanding science program. Unique aspects of the club's activities, instructional strategies, and other areas are discussed. (BC)

  18. Animal Antics. Program Guide for the Texas Reading Club, 1987.

    ERIC Educational Resources Information Center

    Larson, Jeanette

    Developed for the Texas Reading Club, a program sponsored cooperatively by local libraries and the Texas State Library and designed to encourage children and their parents to read and to use the library, this guide is intended to inspire program ideas, including activities, crafts, books, and audiovisuals, appropriate to the Reading Club's 1987…

  19. Simplicity, Harmony Essential to Club of Rome Goals.

    ERIC Educational Resources Information Center

    Lepkowski, Wil

    1979-01-01

    This interview with Aurelio Peccei details the next phase in the Club of Rome's goal of reeducating mankind to global threats. Peccei discusses a variety of topics relating to science and the human condition, including his plans for the implementation of the Club of Rome activities. (BT)

  20. 1. EXTERIOR VIEW OF FRONT OF CLUB HOUSE. BOAT HOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR VIEW OF FRONT OF CLUB HOUSE. BOAT HOUSE AND DOCK TO THE RIGHT. PICTURE TAKEN FROM FRONT YARD OF COTTAGE 231, CAMERA FACING SOUTHWEST. SMALL WOOD FRAME SHED IN FRONT OF CLUB HOUSE STORES FIRE HOSE BUILT AFTER 1980. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  1. Dengue fever outbreak in a recreation club, Dhaka, Bangladesh.

    PubMed

    Wagatsuma, Yukiko; Breiman, Robert F; Hossain, Anowar; Rahman, Mahbubur

    2004-04-01

    An outbreak of dengue fever occurred among employees of a recreation club in Bangladesh. Occupational transmission was characterized by a 12% attack rate, no dengue among family contacts, and Aedes vectors in club areas. Early recognition of the outbreak likely limited its impact.

  2. The Sierra Club--A History. Part 1: Origins & Outings

    ERIC Educational Resources Information Center

    Strong, Douglas H.

    1977-01-01

    This article discusses the early beginnings of the Sierra Club, nearly 100 years ago, and the leadership of John Muir and his contemporaries. Turn of the century photographs show campers and hikers on organized club outing designed to introduce people to mountain wilderness and its preservation. (MA)

  3. Finger clubbing in children with human immunodeficiency virus infection.

    PubMed

    Zar, H J; Hussey, G

    2001-03-01

    We investigated the frequency of finger clubbing in 150 HIV-infected children consecutively hospitalized for acute pneumonia in South Africa and described associated clinical, laboratory and radiological features. Clubbing occurred in 30 of 150 (20%) HIV-infected children compared with one of 99 (1%) HIV-negative control patients, p < 0.001. Clubbing was associated with lower presenting heart and respiratory rates and enlarged parotid glands. Total and CD4 + lymphocytes, CD4:CD8 ratio and LDH were lower in children with clubbing, but serum protein and gammaglobulin were higher. No differences in the prevalence or type of microbial pathogens were found between the two groups. Clubbing was associated with a radiological diagnosis of LIP. Children with clubbing had a lower in-hospital mortality rate than those without clubbing (6.7% vs 24.2%, p = 0.035). In geographical areas with high HIV seroprevalence rates, the presence of clubbing in a child hospitalized for respiratory disease should raise the suspicion of HIV infection. PMID:11284240

  4. Vancouver Island Compassion Club president receives absolute discharge.

    PubMed

    Carey, Ruth

    2002-12-01

    On 5 July 2002, the BC Provincial Court released written reasons for sentencing in R v Lucas. The president of the Vancouver Island Compassion Club had been arrested and charged with possession for the purpose of tracking after police searched the club and his home and seized less than three kilograms of marijuana. PMID:14743811

  5. How to Rank Journals.

    PubMed

    Bradshaw, Corey J A; Brook, Barry W

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68-0.84 Spearman's ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows.

  6. How to Rank Journals

    PubMed Central

    Bradshaw, Corey J. A.; Brook, Barry W.

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68–0.84 Spearman’s ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows. PMID:26930052

  7. How to Rank Journals.

    PubMed

    Bradshaw, Corey J A; Brook, Barry W

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68-0.84 Spearman's ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows. PMID:26930052

  8. Providing medical marijuana: the importance of cannabis clubs.

    PubMed

    Feldman, H W; Mandel, J

    1998-01-01

    In 1996, shortly after the San Francisco Cannabis Club was raided and (temporarily) closed by state authorities, the authors conducted an ethnographic study by interviewing selected former members to ascertain how they had benefited from the use of medical marijuana and how they had utilized the clubs. Interviews were augmented by participant observation techniques. Respondents reported highly positive health benefits from marijuana itself, and underscored even greater benefits from the social aspects of the clubs, which they described as providing important emotional supports. As such, cannabis clubs serve as crucial support mechanisms/groups for people with a wide variety of serious illnesses and conditions. The authors concluded that of the various methods so far proposed, the cannabis clubs afford the best therapeutic setting for providing medical cannabis and for offering a healing environment composed of like-minded, sympathetic friends.

  9. Arthropathy, ankylosing spondylitis, and clubbing of fingers in ulcerative colitis

    PubMed Central

    Jalan, K. N.; Prescott, R. J.; Walker, R. J.; Sircus, W.; McManus, J. P. A.; Card, W. I.

    1970-01-01

    In a retrospective study of 399 patients with ulcerative colitis, 27 patients had colitic arthritis, 17 had ankylosing spondylitis, and 20 had clubbing of the fingers. Colitic arthritis and ankylosing spondylitis were not related to severity, extent of involvement, or duration of colitis. A significant association between colitic arthropathy and other complications of ulcerative colitis, such as pseudopolyposis, perianal disease, eye lesions, skin eruptions, aphthous ulceration, and liver disease has been demonstrated. The outcome of the first referred attack of colitis in the presence of colitic arthritis and ankylosing spondylitis remained uninfluenced. Clubbing of fingers was related to severity, extent of involvement, and length of the history of colitis. A significant association between clubbing of the fingers and carcinoma of the colon, pseudopolyposis, toxic dilatation, and arthropathy has been shown. The frequency of surgical intervention in patients with clubbing was higher but the overall mortality was not significantly different from the patients without clubbing. PMID:5473606

  10. 77 FR 32394 - Safety Zones: Catawba Island Club Fire Works, Catawba Island Club, Port Clinton, OH; Racing for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zones: Catawba Island Club Fire Works, Catawba Island Club, Port Clinton, OH; Racing for Recovery, Lake Erie, Sterling State Park, Monroe, MI; Put-in-Bay Fireworks, Fox's the Dock Pier, South Bass Island, Put-in-Bay, OH AGENCY: Coast Guard, DHS....

  11. Club Drug Use among Young Adults Frequenting Dance Clubs and Other Social Venues in New York City

    ERIC Educational Resources Information Center

    Parsons, Jeffrey T.; Halkitis, Perry N.; Bimbi, David S.

    2006-01-01

    A convenience sample of young adults (ages 18-25) in New York City was recruited to complete anonymous surveys in social venues (either dance clubs or other social settings, such as coffee shops and university "hangouts") regarding their use of "club drugs" (e.g., MDMA/Ecstasy, GHB, ketamine, crystal methamphetamine, cocaine, and LSD).…

  12. Why Children Join and Stay in Sports Clubs: Case Studies in Australian, French and German Swimming Clubs

    ERIC Educational Resources Information Center

    Light, Richard L.; Harvey, Stephen; Memmert, Daniel

    2013-01-01

    This article builds upon research on youth sport clubs conducted from a socio-cultural perspective by reporting on a study that inquired into the reasons why children aged 9-12 joined swimming clubs in France, Germany and Australia. Comprising three case studies it employed a mixed method approach with results considered within the framework of…

  13. Box Cello Middle School Science Clubs

    NASA Astrophysics Data System (ADS)

    Vandegrift, Guy

    1998-10-01

    The Box Cello is a middle school science club which is attempting to (1) understand the cello and (2) design a low-cost starter instrument. We can support and justify this research by adding a third goal: (3) to help supply local science classes with equipment. My policy of spending one entire day each week away from the university, out in a local school is essential to this project. This schedule also permits me to conduct lessons on optics and music in the schools. And, it permits circulation of tools and equipment. A simple calculation demonstrates the great economy achieved by combining science clubs with academic year school visits. Consider the cost of letting 10,000 students in 10 middle schools each learn about and play with a pair of "upside-down" glasses for one hour. A visit to each school for three consecutive weeks would easily permit such a circulation if only 30 pairs were constructed. Assume rhetorically, that the construction of 30 pairs of glasses were to consume the entire estimated annual budget of $100,000. The cost per student would be only ten dollars! The visits, guest lectures, and equipment loans permit informal networking (including lunch) with math, science and music teachers in 10 schools. For more information, visit the http://www.utep.edu/boxcello/

  14. Chaplain Documentation and the Electronic Medical Record: A Survey of ACPE Residency Programs.

    PubMed

    Tartaglia, Alexander; Dodd-McCue, Diane; Ford, Timothy; Demm, Charles; Hassell, Alma

    2016-01-01

    This study explores the extent to which chaplaincy departments at ACPE-accredited residency programs make use of the electronic medical record (EMR) for documentation and training. Survey data solicited from 219 programs with a 45% response rate and interview findings from 11 centers demonstrate a high level of usage of the EMR as well as an expectation that CPE residents document each patient/family encounter. Centers provided considerable initial training, but less ongoing monitoring of chaplain documentation. Centers used multiple sources to develop documentation tools for the EMR. One center was verified as having created the spiritual assessment component of the documentation tool from a peer reviewed published model. Interviews found intermittent use of the student chart notes for educational purposes. One center verified a structured manner of monitoring chart notes as a performance improvement activity. Findings suggested potential for the development of a standard documentation tool for chaplain charting and training.

  15. A Project Management Approach to an ACPE Accreditation Self-study

    PubMed Central

    Iwanowicz, Susan L.; Bailie, George R.; Clarke, David W.; McGraw, Patrick S.

    2007-01-01

    In preparation for an on-site evaluation and accreditation by the American Council on Pharmaceutical Education (ACPE), the Albany College of Pharmacy employed project management techniques to complete a comprehensive self-study. A project lifecycle approach, including planning, production, and turnover phases, was used by the project's Self-Study Steering Committee. This approach, with minimal disruption to college operations, resulted in the completion of the self-study process on schedule. Throughout the project, the Steering Committee maintained a log of functions that either were executed successfully or in hindsight, could have been improved. To assess the effectiveness of the project management approach to the the self-study process, feedback was obtained from the College community through a poststudy survey. This feedback, coupled with the Steering Committee's data on possible improvements, form the basis for the lessons learned during this self-study process. PMID:17533432

  16. Chaplain Documentation and the Electronic Medical Record: A Survey of ACPE Residency Programs.

    PubMed

    Tartaglia, Alexander; Dodd-McCue, Diane; Ford, Timothy; Demm, Charles; Hassell, Alma

    2016-01-01

    This study explores the extent to which chaplaincy departments at ACPE-accredited residency programs make use of the electronic medical record (EMR) for documentation and training. Survey data solicited from 219 programs with a 45% response rate and interview findings from 11 centers demonstrate a high level of usage of the EMR as well as an expectation that CPE residents document each patient/family encounter. Centers provided considerable initial training, but less ongoing monitoring of chaplain documentation. Centers used multiple sources to develop documentation tools for the EMR. One center was verified as having created the spiritual assessment component of the documentation tool from a peer reviewed published model. Interviews found intermittent use of the student chart notes for educational purposes. One center verified a structured manner of monitoring chart notes as a performance improvement activity. Findings suggested potential for the development of a standard documentation tool for chaplain charting and training. PMID:26168408

  17. Water clubs in residential care: is it the water or the club that enhances health and well-being?

    PubMed

    Gleibs, Ilka H; Haslam, Catherine; Haslam, S Alexander; Jones, Janelle M

    2011-10-01

    Recent research suggests that establishing water clubs in care homes can counteract the dangers of dehydration and enhance residents' health and well-being. This study provided an experimental test of this idea, and also explored the possibility that it is the social interaction that clubs provide which delivers health-related benefits. Consistent with this hypothesis, the study found no evidence that, on its own, increased focus on water consumption enhanced residents' health or well-being. However, residents who took part in water clubs showed improved levels of perceived social support, and those who participated in water and control clubs showed beneficial outcomes in terms of the number of General Practitioner calls they required. Consistent with a social identity approach to health and well-being, a mediation analysis also indicated that clubs achieve these positive outcomes by providing social support that helps to build a shared sense of social identity among residents. PMID:21598183

  18. Evaluation of the remineralization capacity of CPP-ACP containing fluoride varnish by different quantitative methods

    PubMed Central

    SAVAS, Selcuk; KAVRÌK, Fevzi; KUCUKYÌLMAZ, Ebru

    2016-01-01

    ABSTRACT Objective The aim of this study was to evaluate the efficacy of CPP-ACP containing fluoride varnish for remineralizing white spot lesions (WSLs) with four different quantitative methods. Material and Methods Four windows (3x3 mm) were created on the enamel surfaces of bovine incisor teeth. A control window was covered with nail varnish, and WSLs were created on the other windows (after demineralization, first week and fourth week) in acidified gel system. The test material (MI Varnish) was applied on the demineralized areas, and the treated enamel samples were stored in artificial saliva. At the fourth week, the enamel surfaces were tested by surface microhardness (SMH), quantitative light-induced fluorescence-digital (QLF-D), energy-dispersive spectroscopy (EDS) and laser fluorescence (LF pen). The data were statistically analyzed (α=0.05). Results While the LF pen measurements showed significant differences at baseline, after demineralization, and after the one-week remineralization period (p<0.05), the difference between the 1- and 4-week was not significant (p>0.05). With regards to the SMH and QLF-D analyses, statistically significant differences were found among all the phases (p<0.05). After the 1- and 4-week treatment periods, the calcium (Ca) and phosphate (P) concentrations and Ca/P ratio were higher compared to those of the demineralization surfaces (p<0.05). Conclusion CPP-ACP containing fluoride varnish provides remineralization of WSLs after a single application and seems suitable for clinical use. PMID:27383699

  19. Know thy journals

    NASA Astrophysics Data System (ADS)

    Kabala, Z. J.

    How do hydrology and water resources journals compare to each other? This question, as noted by McDonnell [1997], is frequently asked by reappointment, tenure, and promotion committees as well as by researchers and graduate students who wonder where to submit their papers. Although the quality of a journal clearly rests with the articles that it publishes, not vice versa, the quality of one's work is often judged in terms of the quality of the journal in which it is published. Therefore, ignoring the journal rankings may be costly regardless of whether or not we deplore the obsession of our society with rankings. What constitutes then a prudent journal choice? Should it be based on the elusive reputation of a journal, its selectivity, its most recent impact factor (defined in the electronic supplement to this article), or other statistics?

  20. 76 FR 37007 - Safety Zone; Stockton Ports Baseball Club Fourth of July Fireworks Display, Stockton, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Stockton Ports Baseball Club Fourth of July... Stockton Ports Baseball Club will sponsor the Stockton Ports Baseball Club Fourth of July Fireworks Display... read as follows: Sec. 165.T11-422 Safety Zone; Stockton Ports Baseball Club Fourth of July...

  1. Promoting undergraduate involvement through the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    McGraw, Allison M.; Austin, Carmen; Noyes, Matthew; Calahan, Jenny; Lautenbach, Jennifer; Henrici, Andrew; Ryleigh Fitzpatrick, M.; Shirley, Yancy L.

    2016-01-01

    The University of Arizona Astronomy Club is devoted to undergraduate success in astronomy, physics, planetary sciences and many other related fields. The club promotes many undergraduate opportunities; research projects, participating in telescope observational runs, sponsoring conference attendance as well as several public outreach opportunities. Research projects involving exoplanet transit observations and radio observations of cold molecular clouds allow undergraduates to experience data collection, telescope operations, data reduction and research presentation. The club hosts many star parties and various other public outreach events for the Tucson, Arizona location. The club often constructs their own outreach materials and structures. The club is currently working on creating a portable planetarium to teach about the night sky on the go even on the cloudiest of nights. The club is also working on creating a binocular telescope with two 10" mirrors as a recreation of the local Large Binocular Telescope for outreach purposes as well. This is a club that strives for undergraduate activity and involvement in a range of academic and extracurricular activates, and is welcoming to all majors of all levels in hopes to spark astronomical interest.

  2. Professional Development Through The University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    McGraw, Allison M.; Nieberding, Megan N.; Austin, Carmen; Hardegree-Ullman, Kevin

    2015-01-01

    The University of Arizona Astronomy Club creates a unique environment for undergraduates to accomplish goals early in their academic career. The club provides research opportunities with advisors, graduate students, and projects organized by fellow undergraduates. Undergraduates that work side-by-side develop strong working relationships which keeps students interested in astronomy and enables them to thrive in their studies and research. Club members are encouraged to attend and present their research at professional conferences where they are exposed early to the scientific research community, learn about internship and REU opportunities, and get information about graduate programs. In addition to preparing undergraduates to thrive in their academic career, the club also offers outreach opportunities for members to actively educate the southern Arizona community. Members of the club design and create many of their outreach materials including 3D models of our local stellar neighborhood and astronomical objects. Astronomy Club has had a positive impact on its members, the Department of Astronomy, and the southern Arizona community for the past seven years. The club continues to strive to improve undergraduate retention and prepare students for their future careers.

  3. Microleakage of Three Types of Glass Ionomer Cement Restorations: Effect of CPP-ACP Paste Tooth Pretreatment

    PubMed Central

    Doozandeh, Maryam; Shafiei, Fereshteh; Alavi, Mostafa

    2015-01-01

    Statement of the Problem Casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) increases the mineral content of tooth structure. This may enhance the chemical bonding of glass ionomer cements (GIC) and marginal sealing of their restorations. Purpose The aim of this study was to evaluate the effect of CPP-ACP paste pretreatment on the microleakage of three types of GIC. Materials and Method In this study, 72 Class V cavities were prepared on the buccal and lingual surfaces of molars with occlusal margins in enamel and gingival margins in root. The cavities were divided into 6 groups. Cavities in group 1 and 2 were restored with Fuji II, group 3 and 4 with Fuji II LC, and group 5 and 6 with Ketac N100 with respect to the manufacturers’ instructions. In groups 2, 4 and 6, CPP-ACP containing paste (MI paste) was placed into the cavities for 3 minutes before being filled with GIC. The teeth were thermocycled, stained with dye, sectioned, and scored for microleakage under stereomicroscope. Kruskall-Wallis and Chi-Square tests were used to analyze the data. Result There were no statistically significant differences between the control and the CPP-ACP pretreatment groups in enamel and dentin margins. In pairwise comparisons, there were no significant differences between the control and the experimental groups in enamel margin, and in dentin margins of G1 and 2, G5 and 6; however, a significant differences was detected in dentin margins between G3 and 4 (p= 0.041). Conclusion CPP-ACP paste pretreatment did not affect the microleakage of Fuji II and Ketac N100 in enamel or dentin, but decreased the microleakage in dentine margins of Fuji II LC when cavity conditioner was applied before surface treatment. PMID:26331147

  4. Using Science to Take a Stand: Action-Oriented Learning in an Afterschool Science Club

    NASA Astrophysics Data System (ADS)

    Hagenah, Sara

    This dissertation study investigates what happens when students participate in an afterschool science club designed around action-oriented science instruction, a set of curriculum design principles based on social justice pedagogy. Comprised of three manuscripts written for journal publication, the dissertation includes 1) Negotiating community-based action-oriented science teaching and learning: Articulating curriculum design principles, 2) Middle school girls' socio-scientific participation pathways in an afterschool science club, and 3) Laughing and learning together: Productive science learning spaces for middle school girls. By investigating how action-oriented science design principles get negotiated, female identity development in and with science, and the role of everyday social interactions as students do productive science, this research fills gaps in the understanding of how social justice pedagogy gets enacted and negotiated among multiple stakeholders including students, teachers, and community members along what identity development looks like across social and scientific activity. This study will be of interest to educators thinking about how to enact social justice pedagogy in science learning spaces and those interested in identity development in science.

  5. Women's Clubs as Educative Agencies: Wilmington, Delaware New Century Club, 1889-1920

    ERIC Educational Resources Information Center

    Taggart, Robert

    2006-01-01

    There is no doubt that women had a role in progressive reform a century ago, despite their lack of vote. However, it may not be so clear what the nature of this reform effort was. This article suggests that women were highly organized in women's clubs that served as a major organ of change in society, and that they had a great impact on education…

  6. Essayists, essays, and hosts: Daniel Hale Williams Medical Reading Club.

    PubMed Central

    Greene Reed, T.; Evans, C. C.

    1996-01-01

    The 66-year-old Daniel Hale Williams Medical Reading Club is an independent reading club comprised of 65 physicians in the metropolitan Washington, DC, area. Members representing all specialty fields meet six times a year for dinner and fellowship, to consider topics of common interest to the profession, and to hear a prepared lecture given by a featured essayist. Club members take turns as hosts for each meeting. This article gives a historical list of these meetings, naming the essayist and the topic, the hosts, and the site of the meetings. PMID:8918074

  7. The Journal Book.

    ERIC Educational Resources Information Center

    Fulwiler, Toby, Ed.

    Essays on the use of journal writing in the classroom are presented in four sections: the language of speculation, journals in the teaching of English, the arts and humanities, and the quantitative disciplines. Titles and authors are as follows: (1) "Dialectical Notebooks and the Audit of Meaning" (A. E. Berthoff); (2) "Desert Island Discourse:…

  8. Journalism in the Movies.

    ERIC Educational Resources Information Center

    Ehrlich, Matthew C.

    1997-01-01

    Analyzes how Hollywood's journalism movie genre has portrayed the news media over the years. Suggests that the movies' relationship to the press reflects a fundamentally ambivalent relationship between the press and the broader culture and that Hollywood explicitly portrays institutional and cultural tensions within journalism which the news media…

  9. Rewriting the Journal

    ERIC Educational Resources Information Center

    Fredette, Michelle

    2012-01-01

    With faculty balking at the price of academic journals, can other digital publishing options get traction? University libraries are no strangers to one of the most popular online alternatives, the open-access archive. These archives enable scholars to upload work--including drafts of articles that are published later in subscription journals--so…

  10. Uses and Benefits of Journal Writing.

    ERIC Educational Resources Information Center

    Hiemstra, Roger

    2001-01-01

    Describes various types of journals: learning journals, diaries, dream logs, autobiographies, spiritual journals, professional journals, interactive reading logs, theory logs, and electronic journals. Lists benefits of journal writing and ways to overcome writing blocks. (Contains 19 references.) (SK)

  11. Biomimetic Remineralization of Demineralized Dentine Using Scaffold of CMC/ACP Nanocomplexes in an In Vitro Tooth Model of Deep Caries

    PubMed Central

    Chen, Zhen; Cao, Shansong; Wang, Haorong; Li, Yanqiu; Kishen, Anil; Deng, Xuliang; Yang, Xiaoping; Wang, Yinghui; Cong, Changhong; Wang, Huajun; Zhang, Xu

    2015-01-01

    Currently, it is still a tough task for dentists to remineralize dentine in deep caries. The aim of this study was to remineralize demineralized dentine in a tooth model of deep caries using nanocomplexes of carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) based on mimicking the stabilizing effect of dentine matrix protein 1 (DMP1) on ACP in the biomineralization of dentine. The experimental results indicate that CMC can stabilize ACP to form nanocomplexes of CMC/ACP, which is able to be processed into scaffolds by lyophilization. In the single-layer collagen model, ACP nanoparticles are released from scaffolds of CMC/ACP nanocomplexes dissolved and then infiltrate into collagen fibrils via the gap zones (40 nm) to accomplish intrafibrillar mineralization of collagen. With this method, the completely demineralized dentine was partially remineralized in the tooth mode. This is a bottom-up remineralizing strategy based on non-classical crystallization theory. Since nanocomplexes of CMC/ACP show a promising effect of remineralization on demineralized dentine via biomimetic strategy, thereby preserving dentinal tissue to the maximum extent possible, it would be a potential indirect pulp capping (IPC) material for the management of deep caries during vital pulp therapy based on the concept of minimally invasive dentistry (MID). PMID:25587986

  12. Overexpression of the olive acyl carrier protein gene (OeACP1) produces alterations in fatty acid composition of tobacco leaves.

    PubMed

    De Marchis, Francesca; Valeri, Maria Cristina; Pompa, Andrea; Bouveret, Emmanuelle; Alagna, Fiammetta; Grisan, Simone; Stanzione, Vitale; Mariotti, Roberto; Cultrera, Nicolò; Baldoni, Luciana; Bellucci, Michele

    2016-02-01

    Taking into account that fatty acid (FA) biosynthesis plays a crucial role in lipid accumulation in olive (Olea europaea L.) mesocarp, we investigated the effect of olive acyl carrier protein (ACP) on FA composition by overexpressing an olive ACP cDNA in tobacco plants. The OeACP1.1A cDNA was inserted in the nucleus or in the chloroplast DNA of different tobacco plants, resulting in extensive transcription of the transgenes. The transplastomic plants accumulated lower olive ACP levels in comparison to nuclear-transformed plants. Moreover, the phenotype of the former plants was characterized by pale green/white cotyledons with abnormal chloroplasts, delayed germination and reduced growth. We suggest that the transplastomic phenotype was likely caused by inefficient olive ACP mRNA translation in chloroplast stroma. Conversely, total lipids from leaves of nuclear transformants expressing high olive ACP levels showed a significant increase in oleic acid (18:1) and linolenic acid (18:3), and a concomitant significant reduction of hexadecadienoic acid (16:2) and hexadecatrienoic acid (16:3). This implies that in leaves of tobacco transformants, as likely in the mesocarp of olive fruit, olive ACP not only plays a general role in FA synthesis, but seems to be specifically involved in chain length regulation forwarding the elongation to C18 FAs and the subsequent desaturation to 18:1 and 18:3. PMID:26560313

  13. 4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING COILS AND CORK-LINED ROOM. CAMERA IS BETWEEN SEVEN AND EIGHT FEET ABOVE FLOOR LEVEL, FACING SOUTHEAST. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  14. 7. CLUBHOUSE. FIREPLACE IN CLUB ROOM. VIEW TO NORTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. CLUBHOUSE. FIREPLACE IN CLUB ROOM. VIEW TO NORTHWEST. - Rainbow Hydroelectric Facility, Clubhouse, On north bank of Missouri River 2 miles Northeast of Great Falls, & end of Rainbow Dam Road, Great Falls, Cascade County, MT

  15. 203. BUILDING 12 (OFFICER'S CLUB), 194041, ALBERT KAHN, INC., ARCHITECTS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    203. BUILDING 12 (OFFICER'S CLUB), 1940-41, ALBERT KAHN, INC., ARCHITECTS. VIEW OF REAR OF BUILDING FROM THE SOUTH, SHOWING POOL AREA, ROOF TERRACES, ETC. - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  16. 10. FIRST FLOOR, NUTFIELD CLUB IN WEST ELL, LOOKING NORTHWEST, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. FIRST FLOOR, NUTFIELD CLUB IN WEST ELL, LOOKING NORTHWEST, ENTRANCE VESTIBULE WITH LEADED GLASS TRANSOM, PRESSED METAL CEILING - Harrington-Smith Block, 18-52 Hanover Street, Manchester, Hillsborough County, NH

  17. 12. Historic American Buildings Survey Topographic Survey of Cosmos Club, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey Topographic Survey of Cosmos Club, 1950, by Bernard Locroft, Civil Engineer (Showing Grounds as They Were at End of Sumner Welles Era) SITE PLAN - Townsend House, 2121 Massachusetts Avenue Northwest, Washington, District of Columbia, DC

  18. Integrated Literacies in a Rural Kenyan Girls' Secondary School Journalism Club

    ERIC Educational Resources Information Center

    Kendrick, Maureen; Early, Margaret; Chemjor, Walter

    2013-01-01

    Our purpose in this paper is to foreground contextual issues in studies of situated writing practices. During a year-long case study in a rural Kenyan secondary school, we applied a number of ethnographic techniques to document how 32 girls (aged 14-18 years) used local cultural and digital resources (i.e., donated digital cameras, voice…

  19. Teachers' Journal Club: Bridging between the Dynamics of Biological Discoveries and Biology Teachers

    ERIC Educational Resources Information Center

    Brill, Gilat; Falk, Hedda; Yarden, Anat

    2003-01-01

    Since biology is one of the most dynamic research fields within the natural sciences, the gap between the accumulated knowledge in biology and the knowledge that is taught in schools, increases rapidly with time. Our long-term objective is to develop means to bridge between the dynamics of biological discoveries and the biology teachers and…

  20. R&W Club Frederick Sews for Kids | Poster

    Cancer.gov

    By Carolynne Keenan, Contributing Writer Sewing enthusiasts of all skill levels are invited to attend a sewing party hosted by the R&W Club Frederick on Feb. 18. Stop by the Building 549 Café Room between 10 a.m. and 4 p.m. to sew for a cause: help the club make pillowcases for ConKerr Cancer, a nonprofit organization that supports children in hospitals across the country.

  1. HPGD mutations cause cranioosteoarthropathy but not autosomal dominant digital clubbing.

    PubMed

    Seifert, Wenke; Beninde, Julia; Hoffmann, Katrin; Lindner, Tom H; Bassir, Christian; Aksu, Fuat; Hübner, Christoph; Verbeek, Nienke E; Mundlos, Stefan; Horn, Denise

    2009-12-01

    Cranio-osteoarthropathy, clinically classified as a variant of primary hypertrophic osteoarthropathy, is a very rare autosomal-recessive condition characterized by delayed closure of the cranial sutures and fontanels, digital clubbing, arthropathy, and periostosis. Recently, mutations in the gene HPGD, which encodes the NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase, were reported in four families affected with primary hypertrophic osteoarthropathy and one family with autosomal-recessive isolated nail clubbing. We report the clinical and molecular findings in four patients from two families affected with cranio-osteoarthropathy and one family with isolated, autosomal dominant digital clubbing. Genome-wide homozygosity mapping identified a locus for cranio-osteoarthropathy harboring the HPGD gene in one affected family. We detected two novel homozygous mutations in HPGD in these families: a missense mutation affecting the NAD(+) binding motif and a frameshift mutation. The clinical presentation in our patients was variable. Digital clubbing and hyperhidrosis were present in all cases. Delayed closure of the cranial sutures and fontanels, periostosis, and arthropathy were not consistent clinical features. No HPGD mutation was detected in a familial case of autosomal dominant isolated digital clubbing. The failure to identify any mutation in a family with an autosomal dominant type of isolated digital clubbing suggests that HPGD is not the major gene for this condition. PMID:19568269

  2. Delayed information flow effect in economy systems. An ACP model study

    NASA Astrophysics Data System (ADS)

    Miśkiewicz, Janusz; Ausloos, M.

    2007-08-01

    Applying any strategy requires some knowledge about the past state of the system. Unfortunately in the case of economy, collecting information is a difficult, expensive and time consuming process. Therefore, the information about the system is usually known only at the end of some well-defined intervals, e.g. through company, national bank inflation data and Gross Domestic Product (GDP) reports, etc. They describe a (market) situation in the past. The time delay is specific to the market branch. It can be very short (e.g. stock market offer is updated every minute or so and this information is quasi-immediately available) or long, like months in the case of agricultural markets, when the decisions are taken based on the results from the previous harvest. The analysis of the information flow delay can be based on the Ausloos-Clippe-Pękalski (ACP) model of spatial evolution of economic systems. The entities can move on a (square) lattice and when meeting take one of the two following decisions: merge or create a new entity. The decision is based on the system state, which is known with some time delay. The effect of system's feedback is hereby investigated. We consider the case of company distribution evolution in a heterogeneous field. The information flow time delay implies different final states, including cycles; it is like a control parameter in a logistic map.

  3. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus

    DOE PAGES

    Wang, Hui; Lu, Yang; Liu, Li; Kim, Sung Won; Hooker, Jacob M.; Fowler, Joanna S.; Tonge, Peter J.

    2014-09-06

    Here we evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of PT119, a potent Staphylococcus aureus enoyl-ACP reductase (saFabI) inhibitor with a Ki value of 0.01 nM and a residence time of 750 min on the enzyme target in mice. PT119 was found to have promising antibacterial activity in two different S. aureus infection models: it caused a 3 log reduction in the CFU’s in a mouse thigh muscle infection model and increased the survival rate from 0% to 50% in a mouse systemic infection model. PT119 was then radiolabeled with carbon-11 to evaluate its biodistribution and PK in both healthymore » and S. aureus infected mice using positron emission tomography (PET). The biodistribution of [11C]PT119 and/or its labeled metabolites did not differ significantly between the healthy group and the infected group, and PT119 was found to distribute equally between serum and tissue during the ~1 h of analysis permitted by the carbon-11 half life. This approach provides important data for PK/PD modeling and is the first step in identifying radiotracers that can non-invasively image bacterial infection in vivo.« less

  4. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus

    SciTech Connect

    Wang, Hui; Lu, Yang; Liu, Li; Kim, Sung Won; Hooker, Jacob M.; Fowler, Joanna S.; Tonge, Peter J.

    2014-09-06

    Here we evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of PT119, a potent Staphylococcus aureus enoyl-ACP reductase (saFabI) inhibitor with a Ki value of 0.01 nM and a residence time of 750 min on the enzyme target in mice. PT119 was found to have promising antibacterial activity in two different S. aureus infection models: it caused a 3 log reduction in the CFU’s in a mouse thigh muscle infection model and increased the survival rate from 0% to 50% in a mouse systemic infection model. PT119 was then radiolabeled with carbon-11 to evaluate its biodistribution and PK in both healthy and S. aureus infected mice using positron emission tomography (PET). The biodistribution of [11C]PT119 and/or its labeled metabolites did not differ significantly between the healthy group and the infected group, and PT119 was found to distribute equally between serum and tissue during the ~1 h of analysis permitted by the carbon-11 half life. This approach provides important data for PK/PD modeling and is the first step in identifying radiotracers that can non-invasively image bacterial infection in vivo.

  5. Who will volunteer? Analysing individual and structural factors of volunteering in Swiss sports clubs.

    PubMed

    Schlesinger, Torsten; Nagel, Siegfried

    2013-01-01

    This article analyses the conditions influencing volunteering in sports clubs. It focuses not only on individual characteristics of volunteers but also on the corresponding structural conditions of sports clubs. It proposes a model of voluntary work in sports clubs based on economic behaviour theory. The influences of both the individual and context levels on the decision to engage in voluntary work are estimated in different multilevel models. Results of these multilevel analyses indicate that volunteering is not just an outcome of individual characteristics such as lower workloads, higher income, children belonging to the sports club, longer club memberships, or a strong commitment to the club. It is also influenced by club-specific structural conditions; volunteering is more probable in rural sports clubs whereas growth-oriented goals in clubs have a destabilising effect.

  6. Journaling: Astronauts Chronicle Missions

    NASA Video Gallery

    Journaling has and will always play an important role in any journey. It’s a simple yet invaluable tool used by behavioral scientists to help assess the mental and emotional states associated with ...

  7. Results of Second Outdoor Comparison Between Absolute Cavity Pyrgeometer (ACP) and Infrared Integrating Sphere (IRIS) Radiometer at PMOD (Presentation)

    SciTech Connect

    Reda, I.; Grobner, J.; Wacker, S.

    2014-01-01

    The Absolute Cavity Pyrgeometer (ACP) and InfraRed Integrating Sphere radiometer (IRIS) are developed to establish a world reference for calibrating pyrgeometers with traceability to SI units. The two radiometers are un-windowed with negligible spectral dependence, and traceable to SI units through the temperature scale (ITS-90). The second outdoor comparison between the two designs was held from September 30 to October 11, 2013 at the Physikalisch-Metorologisches Observatorium Davos (PMOD). The difference between the irradiance measured by ACP and that of the IRIS was within 1 W/m2 (3 IRISs: PMOD + Australia + Germany). From the first and second comparisons, a difference of 4-6 W/m2 was observed between the irradiance measured by ACP&IRIS and that of the interim World Infrared Standard Group (WISG). This presentation includes results from the first and second comparison in an effort to establish the world reference for pyrgeometer calibrations, a key deliverable for the World Meteorological Organization (WMO), and the DOE-ASR.

  8. Epidemiological comparison of injuries in school and senior club rugby.

    PubMed Central

    Lee, A J; Garraway, W M

    1996-01-01

    OBJECTIVE: To determine the frequency, nature, circumstances, and outcome of schoolboy rugby injuries and to compare these injuries with those occurring in senior rugby clubs. METHODS: The study was a prospective cohort study, conducted on 1705 (98%) of 1736 eligible players from nine Edinburgh schools and 1169 (96%) of 1216 eligible players from all 26 senior Scottish Rugby Union clubs (South District) who provided personal details before the 1993-1994 rugby season. Adult linkpersons were appointed to notify the circumstances of all injury episodes occurring in matches or in rugby related training. RESULTS: 154 school players (9%) experienced 210 separate injuries in 186 injury episodes, 80% of which arose in matches. The prevalence rate of schoolboy match injuries was 86.8 (95% confidence interval 73.4 to 100.2) per 1000 player-seasons. Senior club match injury prevalence was much higher at 367.0 (339.4 to 394.6) per 1000 player-seasons. Club players had a higher rate of match injury than school-boys for all injury types. One third of schoolboy match injury episodes occurred in September and the majority of match injury episodes were associated with tackling (40%) or with being tackled (24%). Nine per cent of schoolboy match injury episodes were classified as severe, compared to 13% for clubs. Sixteen per cent (n = 23) of all schoolboy match injury episodes resulted in missed school attendance compared with 27% (n = 117) of all senior club match injury episodes which involved loss of employment or education. CONCLUSIONS: Schoolboy rugby is much safer than senior club rugby and the outcome of injuries that do occur is less disruptive. The relatively high rate of match injury in September migh be reduced by a more intensive period of preseason training. PMID:8889113

  9. Acyl-ACP thioesterases from castor (Ricinus communis L.): an enzymatic system appropriate for high rates of oil synthesis and accumulation.

    PubMed

    Sánchez-García, Alicia; Moreno-Pérez, Antonio J; Muro-Pastor, Alicia M; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2010-06-01

    Acyl-acyl carrier protein (ACP) thioesterases are enzymes that terminate the intraplastidial fatty acid synthesis in plants by hydrolyzing the acyl-ACP intermediates and releasing free fatty acids to be incorporated into glycerolipids. These enzymes are classified in two families, FatA and FatB, which differ in amino acid sequence and substrate specificity. In the present work, both FatA and FatB thioesterases were cloned, sequenced and characterized from castor (Ricinus communis) seeds, a crop of high interest in oleochemistry. Single copies of FatA and FatB were found in castor resulting to be closely related with those of Jatropha curcas. The corresponding mature proteins were heterologously expressed in Escherichia coli for biochemical characterization after purification, resulting in high catalytic efficiency of RcFatA on oleoyl-ACP and palmitoleoyl-ACP and high efficiencies of RcFatB for oleoyl-ACP and palmitoyl-ACP. The expression profile of these genes displayed the highest levels in expanding tissues that typically are very active in lipid biosynthesis such as developing seed endosperm and young expanding leaves. The contribution of these two enzymes to the synthesis of castor oil is discussed.

  10. Dental journals: yesterday and today.

    PubMed

    Woodmansey, Karl

    2012-10-01

    Today's dentists may subscribe to, or receive complimentarily, a number of periodical publications containing technical professional information. Dental journals are the prime example: providing timely, reliable and useful information. The development of dental journals is a component of the evolution of scientific communication. This article reviews the origins and evolution of dental journals, including the Texas Dental Journal. PMID:23311024

  11. Performance of Malaysian Medical Journals

    PubMed Central

    Abrizah, Abdullah

    2016-01-01

    Indexation status matters for scholarly journal prestige and trust. The performance of Malaysian medical journals at the international level is gauged through the global citation databases, and at the national level through MyCite, a national citation indexing system. The performance indicators include journals publication productivity, the citations they garner, and their scores on other bibliometric indices such as journal impact factor (IF), and h-index. There is a growing consciousness amongst journal editorials to improve quality and increase chances of getting indexed in MyCite. Although it is now possible to gauge journal performance within Malaysia, through MyCite, the government and public are concerned about journal performance in international databases. Knowing the performance of journals in MyCite will help the editors and publishers to improve the quality and visibility of Malaysian journals and strategise to bring their journal to the international level of indexation. PMID:27547108

  12. Performance of Malaysian Medical Journals.

    PubMed

    Abrizah, Abdullah

    2016-03-01

    Indexation status matters for scholarly journal prestige and trust. The performance of Malaysian medical journals at the international level is gauged through the global citation databases, and at the national level through MyCite, a national citation indexing system. The performance indicators include journals publication productivity, the citations they garner, and their scores on other bibliometric indices such as journal impact factor (IF), and h-index. There is a growing consciousness amongst journal editorials to improve quality and increase chances of getting indexed in MyCite. Although it is now possible to gauge journal performance within Malaysia, through MyCite, the government and public are concerned about journal performance in international databases. Knowing the performance of journals in MyCite will help the editors and publishers to improve the quality and visibility of Malaysian journals and strategise to bring their journal to the international level of indexation. PMID:27547108

  13. Estimating Impact Forces of Tail Club Strikes by Ankylosaurid Dinosaurs

    PubMed Central

    Arbour, Victoria Megan

    2009-01-01

    Background It has been assumed that the unusual tail club of ankylosaurid dinosaurs was used actively as a weapon, but the biological feasibility of this behaviour has not been examined in detail. Ankylosaurid tail clubs are composed of interlocking vertebrae, which form the handle, and large terminal osteoderms, which form the knob. Methodology/Principal Findings Computed tomographic (CT) scans of several ankylosaurid tail clubs referred to Dyoplosaurus and Euoplocephalus, combined with measurements of free caudal vertebrae, provide information used to estimate the impact force of tail clubs of various sizes. Ankylosaurid tails are modeled as a series of segments for which mass, muscle cross-sectional area, torque, and angular acceleration are calculated. Free caudal vertebrae segments had limited vertical flexibility, but the tail could have swung through approximately 100° laterally. Muscle scars on the pelvis record the presence of a large M. longissimus caudae, and ossified tendons alongside the handle represent M. spinalis. CT scans showed that knob osteoderms were predominantly cancellous, which would have lowered the rotational inertia of the tail club and made it easier to wield as a weapon. Conclusions/Significance Large knobs could generate sufficient force to break bone during impacts, but average and small knobs could not. Tail swinging behaviour is feasible in ankylosaurids, but it remains unknown whether the tail was used for interspecific defense, intraspecific combat, or both. PMID:19707581

  14. School Astronomy Club: from Project to Knowledge

    NASA Astrophysics Data System (ADS)

    Folhas, Alvaro

    2016-04-01

    Prepare a generation of young people for the challenges of the future is a task which forces us to rethink the school, not just for being difficult, but also because students feel that the school has very little to offer, especially something that interests them. Thus, the school is dysfunctional, is ill, and needs prompt treatment. School have to adjust to the new times, and this does not mean changing the old blackboards by advanced interactive whiteboards. The school has to find the way to the students with something that seduce them: the Challenge. The Astronomy Club that I lead in my school is essentially a Project space. Students who voluntarily joined the club, organize themselves according to their interests around projects whose outcome is not defined from the beginning, which requires them to do, undo and redo. Which obliges them to feel the need to ask for help to mathematics or physics to achieve answers, to feel the passion to study with a genuine purpose of learning. Some examples of the work: The younger students are challenged to reproduce the historical astronomical experiments that have opened the doors of knowledge such as the Eratosthenes experiment to determine the perimeter of the Earth (on equinox), or by using congruent triangles, determine the diameter the sun. These students are driven to establish distance scales in the solar system, which, to their astonishment, allows them to clear misconceptions that arise from some pictures of books and allows them to have a scientifically correct idea of the planetary orbit and distance separating the planets of the Solar System. For students from 15 to 18 years, I have to raise the level of the challenges and use the natural tendency of this age bracket to assert making new and exciting things. To this purpose, I am fortunate to have the support of large organizations like NUCLIO, ESA, CERN, and Go-Lab Project, Inspiring Science Education, Open Discovery Space and Global Hands on Universe. Through

  15. East façade, Burton Park Club House, with Amphitheater in foreground, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East façade, Burton Park Club House, with Amphitheater in foreground, view to north from Amphitheater stage (90 mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  16. The Kosmo Club case: clandestine prostitution during the interwar period.

    PubMed

    Settle, Louise

    2014-01-01

    During November 1933 the trial of three men accused of 'living off the earnings of prostitution' captivated the news reading public of Edinburgh. This article uses the detailed trial transcription and newspaper coverage of the Kosmo Club trial to examine the role that dance clubs played within a larger network of clandestine prostitution and the implications this had for the women who worked in these clubs as 'dance partners'. The case study focuses on a key moment in the history of prostitution, one that has not yet received sufficient historical attention, a moment when new technologies, such as the telephone and the motorcar, first began to dramatically alter the landscape of prostitution. Furthermore, the trial offers a rare glimpse of dance partners' experiences, both the dangers they faced and the many ways in which they attempted to resist those who sought to control and exploit them. PMID:25608372

  17. School nurse book clubs: an innovative strategy for lifelong learning.

    PubMed

    Greenawald, Deborah A; Adams, Theresa M

    2008-04-01

    Recognizing the ongoing need for continuing education for school nurses, the authors discuss the use of school nurse book clubs as an innovative lifelong-learning strategy. Current research supports the use of literature in nursing education. This article discusses the benefits of book club participation for school nurses and includes suggested fiction and nonfiction books that can be used to enhance nursing knowledge and practice. Through reading and discussion, school nurses can increase their knowledge of nursing history and current health care issues, thus becoming better prepared to address challenging issues that arise in practice. In addition, the use of literature as a learning strategy allows school nurses to broaden their understanding of unique cultural factors that influence the health beliefs and practices of students and their families. Book club participation can also assist school nurses in honing leadership and communication skills and becoming energized to become better advocates for children and families. PMID:18363439

  18. School nurse book clubs: an innovative strategy for lifelong learning.

    PubMed

    Greenawald, Deborah A; Adams, Theresa M

    2008-04-01

    Recognizing the ongoing need for continuing education for school nurses, the authors discuss the use of school nurse book clubs as an innovative lifelong-learning strategy. Current research supports the use of literature in nursing education. This article discusses the benefits of book club participation for school nurses and includes suggested fiction and nonfiction books that can be used to enhance nursing knowledge and practice. Through reading and discussion, school nurses can increase their knowledge of nursing history and current health care issues, thus becoming better prepared to address challenging issues that arise in practice. In addition, the use of literature as a learning strategy allows school nurses to broaden their understanding of unique cultural factors that influence the health beliefs and practices of students and their families. Book club participation can also assist school nurses in honing leadership and communication skills and becoming energized to become better advocates for children and families.

  19. The Kosmo Club case: clandestine prostitution during the interwar period.

    PubMed

    Settle, Louise

    2014-01-01

    During November 1933 the trial of three men accused of 'living off the earnings of prostitution' captivated the news reading public of Edinburgh. This article uses the detailed trial transcription and newspaper coverage of the Kosmo Club trial to examine the role that dance clubs played within a larger network of clandestine prostitution and the implications this had for the women who worked in these clubs as 'dance partners'. The case study focuses on a key moment in the history of prostitution, one that has not yet received sufficient historical attention, a moment when new technologies, such as the telephone and the motorcar, first began to dramatically alter the landscape of prostitution. Furthermore, the trial offers a rare glimpse of dance partners' experiences, both the dangers they faced and the many ways in which they attempted to resist those who sought to control and exploit them.

  20. Inventories of psychological skills for athletic clubs and school life.

    PubMed

    Ueno, Kohei

    2014-02-01

    Some students who participate in athletic activities transfer the skills acquired in a sports context into other areas of life, while others do not. To identify the specific skills that are transferred or not from sports to the school environment, two inventories were developed: the "Psychological Skills Inventory for Athletic Clubs" and the "Psychological Skills Inventory for School Life." These inventories enable a comparison of skills in a sport context with skills in a school context. In the first stage, 307 Japanese first-year university students who had participated in high school athletic clubs volunteered to take part in a survey to develop these inventories. Analyses indicated that both inventories comprised identical subscales of intrapersonal and interpersonal skills. In the second stage, the reliability and validity of these inventories was confirmed for 531 Japanese high school students who were members of athletic clubs for sports such as soccer and baseball.

  1. The Supernova Club: Urban Youth Engagement that Works

    NASA Astrophysics Data System (ADS)

    Sakimoto, Philip J.; Luckey, V.; Balsara, D.

    2008-05-01

    One of IYA's goals is to promote greater involvement by underrepresented minorities in scientific and engineering careers. IYA can serve as a catalyst for such involvement, but ultimate success requires a longer-term approach. The Supernova Club is an experiment in such a long-term approach. The goal is to see if engagement in a year-round astronomy club can propel youths from some of the most severely disadvantaged areas of our region into careers in science. We recruited club members by bringing astronomy activities to over a hundred youths ages 10-16 who were on campus in Summer 2007 for Notre Dames’ National Youth Sports Program (NYSP). Approximately 20 percent of the participants, most of who were underrepresented minorities and from below poverty level, expressed interest in joining an after-school astronomy club, and thirteen of them ultimately did so. The club meets one evening a week at Notre Dame's Robinson Community Learning Center. Center staff provide extensive support with logistics, meals, training in social skills and conduct, and communications with parents. Notre Dame scientists, assisted by local teachers, provide weekly activities. After one year, the club members have shown large improvements in interest in science and astronomy, ability to focus on tasks or discussions, and general behavior at school and at home. Funding for this first pilot year was provided through education supplements to HST research grants. With NASA space science education funding currently on an indefinite stand down, we are seeking other funds with which to carry on this experiment.

  2. Making Every Day Count: Boys & Girls Clubs' Role in Promoting Positive Outcomes for Teens

    ERIC Educational Resources Information Center

    Arbreton, Amy

    2009-01-01

    The third in a series of reports from P/PV's three-year study of the role Boys & Girls Clubs play in the lives of the youth they serve, "Making Every Day Count" examines how Club participation is related to youth's positive and healthy development in three outcome areas identified by Boys & Girls Clubs of America as central to its mission: good…

  3. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7... (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption... general, this exemption extends to social and recreation clubs which are supported solely by...

  4. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7... (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption... general, this exemption extends to social and recreation clubs which are supported solely by...

  5. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7)-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption provided by... general, this exemption extends to social and recreation clubs which are supported solely by...

  6. Raising Money Through Gift Clubs: A Survey of Techniques at 42 Institutions.

    ERIC Educational Resources Information Center

    Sweeney, Robert D., Comp.

    The way that 42 private schools, colleges, and universities use gift clubs to motivate donors is examined. Based on a nationwide survey, information is presented on the clubs' origins, requirements for membership, methods of enlisting new members, and ways of encouraging current members to increase gifts. Attention is also directed to the clubs'…

  7. Coaches' Perceptions of French Sports Clubs: Health-Promotion Activities, Aims and Coach Motivation

    ERIC Educational Resources Information Center

    Van Hoye, Aurélie; Sarrazin, Philippe; Heuzé, Jean-Philippe; Kokko, Sami

    2015-01-01

    Background: Given the benefits of participating in sport, sports clubs have been recognised as health promoting organizations. To examine health-promotion activities in Finnish sports clubs, Kokko et al. developed a set of standards for health-promoting sports clubs (HPSC). Objective: The present study extends this line of research, by (1)…

  8. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7)-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption provided by... general, this exemption extends to social and recreation clubs which are supported solely by...

  9. Toward an Ecstasy and Other Club Drug (EOCD) Prevention Intervention for Rave Attendees

    ERIC Educational Resources Information Center

    Yacoubian, George S., Jr.; Miller, Sarah; Pianim, Selwyn; Kunz, Michael; Orrick, Erin; Link, Tanja; Palacios, Wilson R.; Peters, Ronald J.

    2004-01-01

    A growing body of recent research has identified that "rave" attendees are at high risk for the use of "club drugs," such as 3,4-methylenedioxymeth-amphetamine (MDMA or "ecstasy"). Rave attendees, however, comprise only one of several club-going populations. In the current study, we explore the prevalence of ecstasy and other club drug (EOCD) use…

  10. An Academic Club Service Learning Project as a Demonstration of Experiential Teaching Tools

    ERIC Educational Resources Information Center

    Bonczek, James L.; Snyder, Lori Unruh; Ellis, Larry R.

    2007-01-01

    We describe our pedagogical approaches and experiences with an academic club service learning project (one semester, 20 club participants, including both graduate students and lower and upper-level undergraduates). Our service learning project responds to the recent demand for more community service-based club projects within the College of…

  11. Charismatic Cops, Patriarchs and a Few Good Women: Leadership, Club Culture and Young Peoples' Drinking

    ERIC Educational Resources Information Center

    Kelly, Peter; Hickey, Chris; Cormack, Sue; Harrison, Lyn; Lindsay, Jo

    2011-01-01

    The paper reports on key findings of a research project that examined the roles that community-based sporting clubs in the Australian state of Victoria play in shaping young people's understandings and uses of alcohol. Our research imagined clubs as community hubs that are located in complex networks that impact on the ways that clubs understand…

  12. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  13. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  14. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  15. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  16. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  17. The Effect of New York's Elite Athletic Clubs on American Amateur Athletic Governance 1870-1915.

    ERIC Educational Resources Information Center

    Wettan, Richard; Willis, Joe

    During the early history of amateur athletics, the large and affluent athletic clubs--mostly in New York City--took the initiative in the formation of the first associations of amateur clubs, the National Association of Amateur Athletes of America (NAAAA), and its successor, the Amateur Athletic Union (AAU). Athletic clubs in New York City in the…

  18. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7)-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption provided by... general, this exemption extends to social and recreation clubs which are supported solely by...

  19. Method of transportation and drinking among club patrons

    PubMed Central

    Bourdeau, Beth; Miller, Brenda A.; Johnson, Mark B.; Voas, Robert B.

    2015-01-01

    Objective The current study examines the variation in alcohol use among nightclub patrons under three transportation conditions: those who departed from a club using modes of transportation other than cars or motorcycles (e.g., pedestrians, bicyclists, subway riders); those who were passengers of drivers (auto/taxi passenger patrons); and those who drove from the club (driving patrons). We seek to determine whether patrons' choice for how to leave the club contributes to their risk, as assessed by blood alcohol concentrations (BAC), after controlling for other factors that may contribute to their BAC including demographic characteristics and social drinking group influences. Methods Data were collected from social drinking groups as they entered and exited clubs for 71 different evenings at ten clubs from 2010 through 2012. Using portal methodology, a research site was established proximal to club entrances. Each individual participant provided data on themselves and others in their group. The present analyses are based upon 1833 individuals who completed both entrance and exit data. Our outcome variable is blood alcohol content (BAC) based upon breath tests attained from patrons at entrance and exit from the club. Independent variables include method of transportation, social group characteristics, drug use, and personal characteristics. We use step-wise multiple regressions to predict entrance BAC, change in BAC from entrance to exit, and exit BAC: first entering individual demographic characteristics, then entering group characteristics, then drug use, and finally entering method of transportation (two dummy coded variables such that drivers are the referent category). Results In sum, in all three of our analyses, only three variables are consistently predictive of BAC: presence of a group member who is frequently drunk and non-driving modes of transportation, either being the passenger or taking alternate methods of transportation. In particular, taking an

  20. Book clubs--outreach opportunities for hospital libraries.

    PubMed

    Stephenson, Priscilla L; Clever, Shannon; Coady, Teresa R; Ender, Deniz; Heyd, Michael; Peth, Sara

    2014-01-01

    Book clubs and discussion groups provide opportunities for hospital librarians to reach out to staff from all areas of their facilities while introducing them to literature reflecting participants' personal and professional interests. Librarians presenting these case studies have coordinated local book clubs where topics ranged from titles about the nature of healing, to leadership development, and patient-centered care. Some also included contemporary novels of interest to participants. No matter the setting or scope of material discussed, each group has provided unique networking opportunities for staff to meet others working in various departments of their facilities.

  1. The professionalization of Carl G. Jung's analytical psychology clubs.

    PubMed

    Samuels, A

    1994-04-01

    This paper addresses (1) the history of a cluster of unusual institutions-analytical psychology clubs--which started in 1916 and by 1934 had become established in many of the countries in the world in which there was interest in the analytical psychology of Carl G. Jung; (2) the conflicts involved in trying to unite the relatively informal earlier "Jung Clubs" with the more formal societies being established by the increasing numbers of professionally trained analysts; and (3) the wider cultural and social issues included in the professionalization of analytical psychology.

  2. Effect of CPP-ACP on the remineralization of acid-eroded human tooth enamel: nanomechanical properties and microtribological behaviour study

    NASA Astrophysics Data System (ADS)

    Zheng, L.; Zheng, J.; Zhang, Y. F.; Qian, L. M.; Zhou, Z. R.

    2013-10-01

    Casein phosphopeptide-stabilized amorphous calcium phosphate (CPP-ACP) has been used to enhance tooth remineralization in the dental clinic. But the contribution of CPP-ACP to the remineralization of acid-eroded human tooth enamel is of widespread controversy. To confirm the application potential of CPP-ACP in the remineralization repair of tooth erosion caused by acid-attack, the effect of remineralization in vitro in 2% w/v CPP-ACP solution on the acid-eroded human tooth enamel was investigated in this study. The repair of surface morphology and the improvement of nanomechanical and microtribological properties were characterized with laser confocal scanning microscope, scanning electron microscope, nanoindentation tester and nanoscratch tester. Results showed that a layer of uneven mineral deposits, which were mainly amorphous calcium phosphate (ACP) in all probability, was observed on the acid-eroded enamel surface after remineralization. Compared with the acid-eroded enamel surface, the nanoindentation hardness and Young's modulus of the remineralized enamel surface obviously increased. Both the friction coefficient and wear volume of the acid-eroded enamel surface decreased after remineralization. However, both the nanomechanical and the anti-wear properties of the remineralized enamel surface were still inferior to those of original enamel surface. In summary, tooth damage caused by acid erosion could be repaired by remineralization in CPP-ACP solution, but the repair effect, especially on the nanomechanical and anti-wear properties of the acid-eroded enamel, was limited. These results would contribute to a further exploration of the remineralization potential of CPP-ACP and a better understanding of the remineralization repair mechanism for acid-eroded human tooth enamel.

  3. Framing Journalism Education

    ERIC Educational Resources Information Center

    Abusharif, Ibrahim N.

    2014-01-01

    Examining the growth, incentives, and progress of overseas campuses of major American educational institutions is an important academic pursuit. To have a complete picture, one must also consider the impact these branch campuses are having on the lives of their students. The Northwestern University in Qatar's journalism program was invited to…

  4. The CATESOL Journal, 2001.

    ERIC Educational Resources Information Center

    Brinton, Donna, Ed.; Ching, Roberta, Ed.

    2001-01-01

    This journal contains the following articles: "Teachers' Perceptions of the Supports and Resources Needed to Prepare English Language Learners for the Future" (Douglas Fisher); "Exploring the Learning Styles of Russian-Speaking Students of English as a Second Language" (Ann C. Wintergerst and Andrea DeCapua); "New Voices in the Classroom:…

  5. JALT Journal, 2001.

    ERIC Educational Resources Information Center

    Fotos, Sandra, Ed.; Jungheim, Nicholas O., Ed.

    2001-01-01

    The two issues in this volume of the "JALT Journal" contain the following articles: "Comprehension and Production Practice in Grammar Instruction: Does Their Combined Use Facilitate Second Language Acquisition?" (Takeo Tanaka); "Professional Development and the JET Program: Insights and Solutions Based on the Sendai City Program" (Anthony Crooks);…

  6. Existentialism in New Journalism.

    ERIC Educational Resources Information Center

    Dalmia, Shikha

    In 1977, John C. Merrill, a mass communication scholar, found that many scholars believed that the sixties movement of new journalism is in some way related to existentialism. To find this out, a study identified six main themes of the philosophy of existentialism (as espoused by Jean-Paul Sartre) and looked for the presence of these themes in the…

  7. The Journalism of Uncertainty.

    ERIC Educational Resources Information Center

    Patterson, Joye

    1979-01-01

    Science journalism is in a period of change from its prior position of reporting the pronouncements of scientists to one of challenging the conclusions of scientists and using multiple sources to comment on scientific discovery. It is necessary that educational institutions anticipate the need for competent scientific journalists. (RE)

  8. Reinvigorating Science Journals

    ERIC Educational Resources Information Center

    Bricker, Patricia

    2007-01-01

    Science-themed books are wonderful tools for emphasizing the importance of observation and journaling. They can also be used to effectively promote literacy skills in science. This article shares a selection of nature books and the ways teachers and students used them to engage in the process of scientific inquiry. (Contains 3 figures and 10…

  9. Electronic Scholarly Journal Publishing.

    ERIC Educational Resources Information Center

    Peek, Robin P.; Pomerantz, Jeffrey P.

    1998-01-01

    Reviews the literature that has led to the possible transformation of scholarly publishing through electronic distribution of journals. Discusses the concepts of scholarly communication and computer mediated communication; network delivery experiments; CD-ROM delivery projects; acceptance by the scholarly community; and research and development.…

  10. Library Journal Classics.

    ERIC Educational Resources Information Center

    Colwell, Ernest Cadman; And Others

    1993-01-01

    Includes reprints of four articles originally published in "Library Journal" in the 1940s and 1960s: "The Role of the Professional School in the University" (Ernest Cadman Colwell); "Library Schools Reshaping Courses" (Lewis F. Stieg); "The New Training Pattern Looks Good" (Harold Lancour); and "The Character and Responsibility of a Graduate…

  11. CACD Journal, 2001.

    ERIC Educational Resources Information Center

    Wickwire, Pat Nellor, Ed.

    2001-01-01

    This journal of the California Association for Counseling and Development attempts to identify the current issues of concern in the counseling field and share research to help improve the professional learning community. The articles in this issue include: "The Editor's Message" (Pat Nellor Wickwire); "The CACD President's Message" (Marcelino…

  12. JALT Journal, 1998.

    ERIC Educational Resources Information Center

    JALT Journal, 1998

    1998-01-01

    This journal (published twice a year) is a publication of the Japan Association for Language Teaching (JALT), a nonprofit professional organization of language teachers dedicated to the improvement of language learning and teaching in Japan. JALT's publications and events serve as vehicles for the exchange of new ideas and techniques, and a means…

  13. JALT Journal, 1999.

    ERIC Educational Resources Information Center

    Fotos, Sandra, Ed.

    1999-01-01

    This journal (usually published twice a year) is a publication of the Japan Association for Language Teaching (JALT), a nonprofit professional organization of language teachers dedicated to the improvement of language learning and teaching in Japan. JALT's publications and events serve as vehicles for the exchange of new ideas and techniques, and…

  14. Decoupling the scholarly journal

    PubMed Central

    Priem, Jason; Hemminger, Bradley M.

    2011-01-01

    Although many observers have advocated the reform of the scholarly publishing system, improvements to functions like peer review have been adopted sluggishly. We argue that this is due to the tight coupling of the journal system: the system's essential functions of archiving, registration, dissemination, and certification are bundled together and siloed into tens of thousands of individual journals. This tight coupling makes it difficult to change any one aspect of the system, choking out innovation. We suggest that the solution is the “decoupled journal (DcJ).” In this system, the functions are unbundled and performed as services, able to compete for patronage and evolve in response to the market. For instance, a scholar might deposit an article in her institutional repository, have it copyedited and typeset by one company, indexed for search by several others, self-marketed over her own social networks, and peer reviewed by one or more stamping agencies that connect her paper to external reviewers. The DcJ brings publishing out of its current seventeenth-century paradigm, and creates a Web-like environment of loosely joined pieces—a marketplace of tools that, like the Web, evolves quickly in response to new technologies and users' needs. Importantly, this system is able to evolve from the current one, requiring only the continued development of bolt-on services external to the journal, particularly for peer review. PMID:22493574

  15. From Conference to Journal

    ERIC Educational Resources Information Center

    McCartney, Robert; Tenenberg, Josh

    2008-01-01

    Revising and extending conference articles for journal publication benefits both authors and readers. The new articles are more complete, and benefit from peer review, feedback from conference presentation, and greater editorial consistency. For those articles that are appropriate, we encourage authors to do this, and present two examples of such…

  16. JALT Journal, 2002.

    ERIC Educational Resources Information Center

    Jungheim, Nicholas O., Ed.

    2002-01-01

    These two journal issues include the following articles: "Assistant Foreign Language Teachers in Japanese High Schools: Focus on the Hosting of Japanese Teachers" (Great Gorsuch); "Communicative Language Teaching (Organizational Effectiveness of Upper Secondary School English Language Departments and Their Commitment toward Communicative Language…

  17. Social Studies Journal, 2003.

    ERIC Educational Resources Information Center

    West, Leo R., Ed.

    2003-01-01

    This theme issue of the "Social Studies Journal" focuses on the worldwide conflict known in the United States as the French and Indian War (1754-1763). The volume is dedicated to examining the conflict in Pennsylvania. Western Pennsylvania became a battle-scarred landscape as the British and French, with their Native American allies, struggled for…

  18. CACD Journal, 2000.

    ERIC Educational Resources Information Center

    Wickwire, Pat Nellor, Ed.

    2000-01-01

    This journal of the California Association for Counseling and Development attempts to identify the current issues of concern in the counseling field and share research to help improve the professional learning community. The articles in this issue include: "The Editor's Message" (Pat Nellor Wickwire); "The CACD President's Message" (Joseph Dear);…

  19. Charting Journalism Degrees.

    ERIC Educational Resources Information Center

    Borden, Victor M. H.

    1998-01-01

    Data are presented on the numbers of African Americans, Hispanic Americans, Asian Americans, and total minority group members receiving associate, bachelor's, master's and doctoral degrees in journalism and mass communication in 1997-98. Colleges and universities graduating the most minorities are also ranked. (MSE)

  20. Collaborative Teaching in Journalism.

    ERIC Educational Resources Information Center

    Haber, Marian Wynne

    Recently, the Communication Department at the University of Texas at Arlington offered an innovative news editing course taught collaboratively by a journalism professor and an editor of the "Fort Worth Star-Telegram," a metropolitan daily newspaper. In 1990 the course was continued on the model describes by R. L. Gates (1989), and in this class…

  1. JALT Journal, 1997.

    ERIC Educational Resources Information Center

    JALT Journal, 1997

    1997-01-01

    The 1997 issues of "JALT Journal" include the following articles: "Influence of Learning Context on Learners' Use of Communication Strategies"; "The Eiken Test: An Investigation"; "Assessing EFL Student Progress in Critical Thinking with the Ennis-Weir Critical Thinking Essay Test"; "Contrastive Rhetoric in Letter Writing"; "Japanese EFL Learners'…

  2. Parent's Journal. [Videotape Series].

    ERIC Educational Resources Information Center

    1999

    Parent's Journal is a set of 16 videotapes for parents of prenatal, infant, and toddler-age children, created by the Alaska Native Home Base Video Project of the Tlingit and Haida Head Start Program. This series offers culturally relevant solutions to the challenges of parenting, drawing on the life stories and experiences of capable mothers and…

  3. Pedagogy Journal, 2000.

    ERIC Educational Resources Information Center

    Marashio, Nancy, Ed.; Marashio, Paul, Ed.

    2000-01-01

    The theme of the 2000 issue of Pedagogy Journal is finding a "sense of place" within the higher education community. Articles contained discuss this issue as it pertains to different aspects of the postsecondary system. These articles include: (1) "The Role of Left-Brain/Right-Brain Learning Theory in Personal Computer Courses" (Jack Wakelin); (2)…

  4. Pedagogy Journal, 2001.

    ERIC Educational Resources Information Center

    Marashio, Nancy, Ed.; Marashio, Paul, Ed.

    2001-01-01

    This annual journal contains articles about pedagogy written by faculty members of New Hampshire's Community Technical Colleges. Included in this volume are: (1) "Preface" by Paul Marashio; (2) "Distance Education: An Educator's Experience as an On-Line Student" by John Marclay; (3) "Emergence" by L. Sue Webb; (4) "Art and Nursing" by Karen A.…

  5. What are Journals for?

    PubMed

    Rallison, S P

    2015-03-01

    'The secret is comprised in three words - work, finish, publish.' Michael Faraday There are many reasons doctors want to publish their work. For most at an early stage in their career, this may be to add a line to their curriculum vitae and advance their careers but for academics, publishing is an expectation. Many will believe they have something important to say, and wish to provoke debate and discussion; others wish to share knowledge and experiences, which in medicine can lead to a satisfying change in clinical practice. All serve to register one's idea and educate others. However, for some, the reason is as basic as money. As we celebrate the 350th anniversary of the first academic publication, perhaps we have come full circle when it comes to why people publish? Publishing is a flourishing business. There were approximately 28,100 active scholarly peer-reviewed journals in mid-2012, collectively publishing about 1.8-1.9 million articles per year. The number of articles published each year and the number of journals have both grown steadily for more than two centuries, by about 3% and 3.5% per year respectively. (1) Journals have a responsibility to refine and define information and act as a scientific filter. Many of us will receive daily invitations in our email inbox from eclectic and new journals that are likely to take anything - is the filter now too porous? But this industry is like any other commercial activity and the supply still far outstrips the demand. Perhaps the internet revolution has merely fuelled our hunger to publish more? The launch of this exciting and innovative series about publishing coincides with the 350th celebration of the publication of the first academic journal. In the age of social media, the first question is 'What are journals for?', which Simon Rallison sets out to answer. Simon is Director of Publications at the Physiological Society, and was previously a journal publisher with Earthscan, Springer and Blackwell. Writing is

  6. What are Journals for?

    PubMed

    Rallison, S P

    2015-03-01

    'The secret is comprised in three words - work, finish, publish.' Michael Faraday There are many reasons doctors want to publish their work. For most at an early stage in their career, this may be to add a line to their curriculum vitae and advance their careers but for academics, publishing is an expectation. Many will believe they have something important to say, and wish to provoke debate and discussion; others wish to share knowledge and experiences, which in medicine can lead to a satisfying change in clinical practice. All serve to register one's idea and educate others. However, for some, the reason is as basic as money. As we celebrate the 350th anniversary of the first academic publication, perhaps we have come full circle when it comes to why people publish? Publishing is a flourishing business. There were approximately 28,100 active scholarly peer-reviewed journals in mid-2012, collectively publishing about 1.8-1.9 million articles per year. The number of articles published each year and the number of journals have both grown steadily for more than two centuries, by about 3% and 3.5% per year respectively. (1) Journals have a responsibility to refine and define information and act as a scientific filter. Many of us will receive daily invitations in our email inbox from eclectic and new journals that are likely to take anything - is the filter now too porous? But this industry is like any other commercial activity and the supply still far outstrips the demand. Perhaps the internet revolution has merely fuelled our hunger to publish more? The launch of this exciting and innovative series about publishing coincides with the 350th celebration of the publication of the first academic journal. In the age of social media, the first question is 'What are journals for?', which Simon Rallison sets out to answer. Simon is Director of Publications at the Physiological Society, and was previously a journal publisher with Earthscan, Springer and Blackwell. Writing is

  7. The Club of Rome and its computer.

    PubMed

    Chase, S

    1973-03-01

    When the Club of Rome, an assemblage of 75 scientists and businessmen gathered to study the ''predicament of mankind in the face of technology growing at an exponential rate,'' issued its computer study it launched a battle between proponents of gross national product and those favoring quality of life. The computer simulation studied the interaction of population growth, food supply, inductrial production, resource use, and pollution under varying conditions. It concluded that our industrial system is headed for too many people in relation to food and living space, too much production in relation to natural resources, and for too much pollution. This will affect all countries. The traditional economists say the continued growth of the gross national product is the only way to ensure better living conditions while the ecologists point out that quality of life is being destroyed. The author cites arguments both for and against the quality-of-life view. The problem is that continued industrial growth creates wants as well as satisfying them and leads to waste as well as needful consumption. John Stuart Mill stated 100 years ago that the world could not support continued technological expansion and society must reach an equilibrium. 8 steps must be taken if the planet is to reach such an equilibrium, which is essential to the survival of all: 1) a zero rate of population growth, although there may be variations between countries with some over and some under; 2) a zero rate of industrial output with overall new investment equal to overall rate of industrial depreciation; 3) a policy of recycling and conserving material resources; 4) an adequate budget of food, shelter, clothing, health services, and education for every human being (a budget which does not allow for autos and air conditioning); 5) a sharp decline in consumption of material goods in affluent societies with a corresponding shift to more services and an increase in material goods for low energy societies

  8. The Club of Rome and its computer.

    PubMed

    Chase, S

    1973-03-01

    When the Club of Rome, an assemblage of 75 scientists and businessmen gathered to study the ''predicament of mankind in the face of technology growing at an exponential rate,'' issued its computer study it launched a battle between proponents of gross national product and those favoring quality of life. The computer simulation studied the interaction of population growth, food supply, inductrial production, resource use, and pollution under varying conditions. It concluded that our industrial system is headed for too many people in relation to food and living space, too much production in relation to natural resources, and for too much pollution. This will affect all countries. The traditional economists say the continued growth of the gross national product is the only way to ensure better living conditions while the ecologists point out that quality of life is being destroyed. The author cites arguments both for and against the quality-of-life view. The problem is that continued industrial growth creates wants as well as satisfying them and leads to waste as well as needful consumption. John Stuart Mill stated 100 years ago that the world could not support continued technological expansion and society must reach an equilibrium. 8 steps must be taken if the planet is to reach such an equilibrium, which is essential to the survival of all: 1) a zero rate of population growth, although there may be variations between countries with some over and some under; 2) a zero rate of industrial output with overall new investment equal to overall rate of industrial depreciation; 3) a policy of recycling and conserving material resources; 4) an adequate budget of food, shelter, clothing, health services, and education for every human being (a budget which does not allow for autos and air conditioning); 5) a sharp decline in consumption of material goods in affluent societies with a corresponding shift to more services and an increase in material goods for low energy societies

  9. The Writer's Journal: 40 Contemporary Writers and Their Journals.

    ERIC Educational Resources Information Center

    Bender, Sheila, Ed.

    This anthology presents excerpts from the journals of 40 of today's most noted writers, along with their comments on the role of journal-keeping in creating their art. Besides being generally instructional to other writers and a lesson in how to create a personal journal, the anthology is a look at writers in the midst of creating. It includes…

  10. Three Journal Similarity Metrics and Their Application to Biomedical Journals

    PubMed Central

    D′Souza, Jennifer L.; Smalheiser, Neil R.

    2014-01-01

    In the present paper, we have created several novel journal similarity metrics. The MeSH odds ratio measures the topical similarity of any pair of journals, based on the major MeSH headings assigned to articles in MEDLINE. The second metric employed the 2009 Author-ity author name disambiguation dataset as a gold standard for estimating the author odds ratio. This gives a straightforward, intuitive answer to the question: Given two articles in PubMed that share the same author name (lastname, first initial), how does knowing only the identity of the journals (in which the articles were published) predict the relative likelihood that they are written by the same person vs. different persons? The article pair odds ratio detects the tendency of authors to publish repeatedly in the same journal, as well as in specific pairs of journals. The metrics can be applied not only to estimate the similarity of a pair of journals, but to provide novel profiles of individual journals as well. For example, for each journal, one can define the MeSH cloud as the number of other journals that are topically more similar to it than expected by chance, and the author cloud as the number of other journals that share more authors than expected by chance. These metrics for journal pairs and individual journals have been provided in the form of public datasets that can be readily studied and utilized by others. PMID:25536326

  11. Positioning Open Access Journals in a LIS Journal Ranking

    ERIC Educational Resources Information Center

    Xia, Jingfeng

    2012-01-01

    This research uses the h-index to rank the quality of library and information science journals between 2004 and 2008. Selected open access (OA) journals are included in the ranking to assess current OA development in support of scholarly communication. It is found that OA journals have gained momentum supporting high-quality research and…

  12. ASM Journals Eliminate Impact Factor Information from Journal Websites.

    PubMed

    Casadevall, Arturo; Bertuzzi, Stefano; Buchmeier, Michael J; Davis, Roger J; Drake, Harold; Fang, Ferric C; Gilbert, Jack; Goldman, Barbara M; Imperiale, Michael J; Matsumura, Philip; McAdam, Alexander J; Pasetti, Marcela F; Sandri-Goldin, Rozanne M; Silhavy, Thomas; Rice, Louis; Young, Jo-Anne H; Shenk, Thomas

    2016-01-01

    Many scientists attempt to publish their work in a journal with the highest possible journal impact factor (IF). Despite widespread condemnation of the use of journal IFs to assess the significance of published work, these numbers continue to be widely misused in publication, hiring, funding, and promotion decisions (1, 2). PMID:27408939

  13. Three journal similarity metrics and their application to biomedical journals.

    PubMed

    D'Souza, Jennifer L; Smalheiser, Neil R

    2014-01-01

    In the present paper, we have created several novel journal similarity metrics. The MeSH odds ratio measures the topical similarity of any pair of journals, based on the major MeSH headings assigned to articles in MEDLINE. The second metric employed the 2009 Author-ity author name disambiguation dataset as a gold standard for estimating the author odds ratio. This gives a straightforward, intuitive answer to the question: Given two articles in PubMed that share the same author name (lastname, first initial), how does knowing only the identity of the journals (in which the articles were published) predict the relative likelihood that they are written by the same person vs. different persons? The article pair odds ratio detects the tendency of authors to publish repeatedly in the same journal, as well as in specific pairs of journals. The metrics can be applied not only to estimate the similarity of a pair of journals, but to provide novel profiles of individual journals as well. For example, for each journal, one can define the MeSH cloud as the number of other journals that are topically more similar to it than expected by chance, and the author cloud as the number of other journals that share more authors than expected by chance. These metrics for journal pairs and individual journals have been provided in the form of public datasets that can be readily studied and utilized by others.

  14. Our World: Journaling in Space

    NASA Video Gallery

    Learn how famous explorers, scientists and even NASA use journals and science notebooks to record observations about Our World. See why journaling is important on the International Space Station to...

  15. Publishing corruption discussion: predatory journalism.

    PubMed

    Jones, James W; McCullough, Laurence B

    2014-02-01

    Dr Spock is a brilliant young vascular surgeon who is up for tenure next year. He has been warned by the chair of surgery that he needs to increase his list of publications to assure passage. He has recently had a paper reviewed by one of the top journals in his specialty, Journal X-special, with several suggestions for revision. He received an e-mail request for manuscript submission from a newly minted, open access, Journal of Vascular Disease Therapy, which promises a quick and likely favorable response for a fee. What should be done? A. Send the paper to another peer reviewed journal with the suggested revisions. B. Resubmit the paper to Journal X-special. C. Submit to the online journal as is to save time. D. Submit to the online journal and another regular journal. E. Look for another job.

  16. Meet the APS Journal Editors

    NASA Astrophysics Data System (ADS)

    2016-05-01

    The Editors of the APS journals invite you to join them for conversation. The Editors will be available to answer questions, hear your ideas, and discuss any comments about the journals. All are welcome. Light refreshments will be served.

  17. Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor

    SciTech Connect

    Chemler, Joseph A.; Buchholz, Tonia J.; Geders, Todd W.; Akey, David L.; Rath, Christopher M.; Chlipala, George E.; Smith, Janet L.; Sherman, David H.

    2012-08-10

    Germicidin synthase (Gcs) from Streptomyces coelicolor is a type III polyketide synthase (PKS) with broad substrate flexibility for acyl groups linked through a thioester bond to either coenzyme A (CoA) or acyl carrier protein (ACP). Germicidin synthesis was reconstituted in vitro by coupling Gcs with fatty acid biosynthesis. Since Gcs has broad substrate flexibility, we directly compared the kinetic properties of Gcs with both acyl-ACP and acyl-CoA. The catalytic efficiency of Gcs for acyl-ACP was 10-fold higher than for acyl-CoA, suggesting a strong preference toward carrier protein starter unit transfer. The 2.9 {angstrom} germicidin synthase crystal structure revealed canonical type III PKS architecture along with an unusual helical bundle of unknown function that appears to extend the dimerization interface. A pair of arginine residues adjacent to the active site affect catalytic activity but not ACP binding. This investigation provides new and surprising information about the interactions between type III PKSs and ACPs that will facilitate the construction of engineered systems for production of novel polyketides.

  18. 75 FR 34374 - Safety Zone; Stockton Ports Baseball Club/City of Stockton, 4th of July Fireworks Display...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Stockton Ports Baseball Club/City of... Ports Baseball Club and the City of Stockton will sponsor the Stockton Ports Baseball Club/City of... Ports Baseball Club/City of Stockton 4th of July Fireworks Display, Stockton, CA. (a) Location....

  19. 20 CFR 404.1014 - Domestic service by a student for a local college club, fraternity or sorority.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... college club, fraternity or sorority. 404.1014 Section 404.1014 Employees' Benefits SOCIAL SECURITY... a local college club, fraternity or sorority. (a) General. If you are a student and do work of a household nature in or about the club rooms or house of a local college club or local chapter of a...

  20. 20 CFR 404.1014 - Domestic service by a student for a local college club, fraternity or sorority.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... college club, fraternity or sorority. 404.1014 Section 404.1014 Employees' Benefits SOCIAL SECURITY... a local college club, fraternity or sorority. (a) General. If you are a student and do work of a household nature in or about the club rooms or house of a local college club or local chapter of a...

  1. Comparison of Coaches' Perceptions and Officials Guidance towards Health Promotion in French Sport Clubs: A Mixed Method Study

    ERIC Educational Resources Information Center

    Van Hoye, A.; Heuzé, J.-P.; Larsen, T.; Sarrazin, P.

    2016-01-01

    Despite the call to improve health promotion (HP) in sport clubs in the existing literature, little is known about sport clubs' organizational capacity. Grounded within the setting-based framework, this study compares HP activities and guidance among 10 football clubs. At least three grassroots coaches from each club (n = 68) completed the Health…

  2. A Cross-Cultural Study on Meaning and the Nature of Children's Experiences in Australian and French Swimming Clubs

    ERIC Educational Resources Information Center

    Light, Richard

    2010-01-01

    This article reports on a study conducted in Australia and France that inquired into the meaning and the nature of children's experiences of being in swimming clubs with a focus on the positive aspects of membership that keep them in their clubs. Three-month long case studies were conducted in a club in Australia and in a club in France, employing…

  3. Extracurricular School Clubs: A Time for Fun and Learning

    ERIC Educational Resources Information Center

    Pence, Alicia R.; Dymond, Stacy K.

    2015-01-01

    Inclusion in school clubs affords students with severe disabilities learning opportunities as well as a natural context for addressing curricula. These learning opportunities expand the number of settings in which students can practice, master, and generalize skills associated with priority IEP objectives. Teaching skills within natural activities…

  4. Imaginary Indians: Representations of Native Americans in Scholastic Reading Club

    ERIC Educational Resources Information Center

    Chaudhri, Amina; Schau, Nicole

    2016-01-01

    Scholastic Reading Clubs are a popular and inexpensive way for teachers to build classroom libraries and for parents to purchase books for their children. The books made accessible to children through the order forms are assumed to be suitable for young readers in terms of their content, popularity, currency, and curricular relevance.…

  5. Marshall Amateur Radio Club experiment (MARCE) post flight data analysis

    NASA Technical Reports Server (NTRS)

    Rupp, Charles C.

    1987-01-01

    The Marshall Amateur Radio Club Experiment (MARCE) data system, the data recorded during the flight of STS-61C, the manner in which the data was reduced to engineering units, and the performance of the student experiments determined from the data are briefly described.

  6. Argonne Director Eric Isaacs addresses the National Press Club

    ScienceCinema

    Eric Isaccs

    2016-07-12

    Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

  7. To the Library and Beyond! 2001 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Bonet, Elida Guardia; Coker, Lisa; Cowan, Julie; Green, Kathleen D.; Hager, Tina; Muller-McKinstry, Adelle; McMahon, Dorothy; Meyers, Sally; Parrish, Leila; Schill, Victor Lynn; Travis, Gayle; Vigil, Angel; Waits, Cara A.; Youngblood, Lisa

    The Texas Reading Club is designed to encourage youth to read for pleasure and to promote library usage.The theme for 2001 is "To the Library and Beyond!" and emphasizes ways in which a visit to the library leads young minds to explore world geography and cultures, nature and the environment, college and careers, computers, and great literature. A…

  8. Sports Club Development--The '70'S Community Involvement.

    ERIC Educational Resources Information Center

    Juncker, D. F.

    A large-scale movement toward sports clubs is evolving in colleges and universities in response to widespread professionalism in varsity sports, limited sports opportunities available to highly skilled student athletes, and most importantly, substantial increases in the desire for sports participation by students in general, as a supplement to…

  9. Kids Food CyberClub. Teacher's Guide. First Edition.

    ERIC Educational Resources Information Center

    Belyea, Monica

    This guide is designed to help teachers educate students to be healthier now and in the future. It presents fun, learner-centered activities about nutrition, food, hunger, and food sources. It offers an overview of each section of the Kids Food CyberClub web site, and classroom activities teachers can use to expand on information students will…

  10. Mission Possible: Spy a Book! 2003 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Heard, Adriana Flores; Ingham, Donna; McDermott, Joe; Meyer, Sally; Parrish, Leila; Schill, Victor; Trevino, Rose

    The purpose of this manual for the 2003 Texas Reading Club, "Mission Possible: Spy a Book!" is to assist library staff who serve youth by suggesting ideas for programs that will attract children to the library. The following chapters are included: (1) Marketing, Cooperation and PR; (2) Serving Children with Disabilities; (3) Theme Songs; (4)…

  11. "Space Capers." Texas Reading Club 1982: A Librarian's Planning Handbook.

    ERIC Educational Resources Information Center

    Rudd, Peggy Jemelka

    Originally designed as a summer program to be offered through the network of bookmobiles and rural public libraries in the state, the Texas Reading Club is now also promoted year round by school and institutional libraries to encourage young readers and to acquaint them with libraries and their services. A theme, formats and ideas, and basic…

  12. Sexy ladies sexing ladies: women as consumers in strip clubs.

    PubMed

    Wosick-Correa, Kassia R; Joseph, Lauren J

    2008-01-01

    Recent shifts in the consumer base of the sex industry have involved greater female attendance in strip clubs. This article examines how strip clubs and dancers incorporate female patrons into a sexualized space traditionally designed for men by identifying three interactional processes: passing over, sidestaging, and tailoring. We suggest dancers pass over women because they perceive female patron behavior to include resistance to "buying the game" and spending patterns that diverge from male customers. Drawing on Goffman's dramaturgical analysis, we suggest the dynamic relationship between dancer and female patron involves what we term sidestaging, which refers to both dancers' disclosure and how the club's spatial organization inhibits the construction of women as customers through sharing gendered spaces, such as the bathroom. We argue that when a dancer tailors her lap dance for a female patron, she succeeds in acknowledging the female customer's sexual subjectivity and potential same-sex desires by providing an individualized avenue for exploring an erotic experience. Finally, we discuss data implications for understanding how same-sex desire and sexual identity operate in an environment that eroticizes the female form, and how the strip club becomes a potential space for engaging in same-sex eroticism that includes elements of play.

  13. Ways of Using Science Clubs to Bridge into Secondary Schools

    ERIC Educational Resources Information Center

    Chapman, Steven

    2003-01-01

    Traditionally science clubs have been seen as a lunchtime or after-school activity, run by volunteer teachers giving up their spare time. Increasingly, however, they are being used creatively as a way of delivering important curriculum enhancement activities or even as a vehicle for the science part of whole-school priorities such as working with…

  14. Engaging Teens in Recreational Reading through Book Clubs

    ERIC Educational Resources Information Center

    Heard, Jil'Lana

    2015-01-01

    Being concerned about the decline in recreational reading among adolescent students, with several colleagues, the author began brainstorming ideas on how to better promote reading. One of the ideas that kept recurring was hosting a book club for students. Since the focus would be on reintroducing the idea of reading for pleasure and not just for…

  15. The Hip-Hop club scene: Gender, grinding and sex.

    PubMed

    Muñoz-Laboy, Miguel; Weinstein, Hannah; Parker, Richard

    2007-01-01

    Hip-Hop culture is a key social medium through which many young men and women from communities of colour in the USA construct their gender. In this study, we focused on the Hip-Hop club scene in New York City with the intention of unpacking narratives of gender dynamics from the perspective of young men and women, and how these relate to their sexual experiences. We conducted a three-year ethnographic study that included ethnographic observations of Hip-Hop clubs and their social scene, and in-depth interviews with young men and young women aged 15-21. This paper describes how young people negotiate gender relations on the dance floor of Hip-Hop clubs. The Hip-Hop club scene represents a context or setting where young men's masculinities are contested by the social environment, where women challenge hypermasculine privilege and where young people can set the stage for what happens next in their sexual and emotional interactions. Hip-Hop culture therefore provides a window into the gender and sexual scripts of many urban minority youth. A fuller understanding of these patterns can offer key insights into the social construction of sexual risk, as well as the possibilities for sexual health promotion, among young people in urban minority populations.

  16. Sexy ladies sexing ladies: women as consumers in strip clubs.

    PubMed

    Wosick-Correa, Kassia R; Joseph, Lauren J

    2008-01-01

    Recent shifts in the consumer base of the sex industry have involved greater female attendance in strip clubs. This article examines how strip clubs and dancers incorporate female patrons into a sexualized space traditionally designed for men by identifying three interactional processes: passing over, sidestaging, and tailoring. We suggest dancers pass over women because they perceive female patron behavior to include resistance to "buying the game" and spending patterns that diverge from male customers. Drawing on Goffman's dramaturgical analysis, we suggest the dynamic relationship between dancer and female patron involves what we term sidestaging, which refers to both dancers' disclosure and how the club's spatial organization inhibits the construction of women as customers through sharing gendered spaces, such as the bathroom. We argue that when a dancer tailors her lap dance for a female patron, she succeeds in acknowledging the female customer's sexual subjectivity and potential same-sex desires by providing an individualized avenue for exploring an erotic experience. Finally, we discuss data implications for understanding how same-sex desire and sexual identity operate in an environment that eroticizes the female form, and how the strip club becomes a potential space for engaging in same-sex eroticism that includes elements of play. PMID:18686149

  17. "Tipping" Teachers toward Change: Developing Leadership Characteristics through Book Club

    ERIC Educational Resources Information Center

    Klinker, JoAnn Franklin; Watson, Patricia A.; Furgerson, Paige; Halsey, Pamela; Janisch, Carole

    2010-01-01

    Teacher leadership is difficult because teachers often lack encouragement and opportunities to implement ideas that deliberately and strategically interact with and tap power structures in schools. In this study, a book club of university faculty and middle school teachers provided teacher leaders with a template for change around concepts…

  18. 17. Interior of upper level (Turf Club level) of south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Interior of upper level (Turf Club level) of south and west additions to the Clubhouse. Camera pointed W. Stairs in foreground lead to the 'Gallery' room. Stairs in background lead to the 'Callahan' room. 'Broderick' room (not shown) is entered from south side of 'Gallery' room. (July 1993) - Longacres, Clubhouse & Additions, 1621 Southwest Sixteenth Street, Renton, King County, WA

  19. Bullying 101: The Club Crew's Guide to Bullying Prevention

    ERIC Educational Resources Information Center

    PACER Center, 2013

    2013-01-01

    "Bullying 101" is the Club Crew's Guide to Bullying Prevention. A visually-friendly, age-appropriate, 16-page colorful guide for students to read or for parents to use when talking with children, this guide describes and explains what bullying is and is not, the roles of other students, and tips on what each student can do to prevent…

  20. Boys and Girls Clubs in Public Housing. Final Research Report.

    ERIC Educational Resources Information Center

    Pope, Carl E.; And Others

    This report presents findings and recommendations resulting from the evaluation of programs implemented in 15 cities by the Boys and Girls Clubs of America. These programs were implemented to distribute variations on the "Weed and Seed" program and its provision of crime and drug prevention programs. The overall goal of Weed and Seed was to form…

  1. Teens, Crime, and the Community in Boys & Girls Clubs.

    ERIC Educational Resources Information Center

    Carlson, Andrea

    Teens, Crime, and the Community (TCC) curriculum creates an awareness among teens of the crime problems facing our communities and how they affect our nation. It encourages youth to take responsibility for reducing crime and victimization, making schools and neighborhoods safer. Boys and Girls Clubs offer a variety of programs for youth, and TCC…

  2. Clinical Teaching by Video-Enhanced Study Club Discussion Sessions.

    ERIC Educational Resources Information Center

    Roberts, Douglass B.; And Others

    1988-01-01

    The Loma Linda University School of Dentistry's "study club" method of teaching operative dentistry involves a four-hour clinical operating session and an hour-long discussion immediately following. Videotape recordings of the operative procedures are used successfully in the discussion period to enhance observation and recall. (MSE)

  3. Tracking Club Sport Participation from Childhood to Early Adulthood

    ERIC Educational Resources Information Center

    Richards, Rosalina; Williams, Sheila; Poulton, Richie; Reeder, Anthony I.

    2007-01-01

    This study examined the strength of tracking sport participation from childhood to early adulthood among the Dunedin Multidisciplinary Health and Development Study cohort. Participation in sport, dance, or gymnastics as part of a club or group (outside of school) was assessed at ages 7, 9, 15, 18, and 21 years. In addition to the traditionally…

  4. 8. INTERIOR VIEW OF CLUB HOUSE BEDROOM ON SOUTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR VIEW OF CLUB HOUSE BEDROOM ON SOUTHEAST CORNER OF HOTEL. BOAT HOUSE AND DOCK VISIBLE FROM WINDOW ON LEFT; SWAN FALLS POWER HOUSE AND CONSTRUCTION SITE VISIBLE FROM WINDOW ON RIGHT. CAMERA FACING WEST/NORTHWEST. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  5. The Environmental Message of Audubon and the Sierra Club Bulletin

    ERIC Educational Resources Information Center

    Hoesterey, John; Bowman, James S.

    1976-01-01

    This study attempted to determine the impact of environmental values on two periodicals: Audubon and the Sierra Club Bulletin. The two periodicals were analyzed for the period 1969-1974. Many conclusions are presented including that the Audubon Society may be undergoing an organizational change by becoming more politically oriented. (BT)

  6. Transnational Alliances: "La Clase Mágica--Nepohualtzitzin" Ethnomathematics Club

    ERIC Educational Resources Information Center

    Prieto, Linda; Claeys, Lorena; González, Everardo Lara

    2015-01-01

    This article exposes the ancient "Nepohualtzitzin" as an important contemporary mathematical tool. The design and development of "Nepohualtzitzin" Ethnomathematics Clubs (NECs) in predominantly Latina/o and low-income schools is also presented. NECs provide informal learning opportunities to develop and strengthen cultural…

  7. A Case Study of a Mother/Daughter Science Club.

    ERIC Educational Resources Information Center

    Chandler, Frances Tate; Parsons, Sharon

    This paper describes a case study of a Mother/Daughter Science Club which was established to explore the issue of adolescent girls' increasingly negative attitudes towards science and math. Data was collected on participants' (n=40, 20 pre-adolescent fifth-grade girls and their mothers) attitudes toward math and science through the use of…

  8. Criminal charges against marijuana compassion club members stayed.

    PubMed

    Mysko, Barbara

    2004-12-01

    As reported in a newspaper article, a British Columbia Provincial Court judge has stayed charges of possession of marijuana for the purpose of trafficking. Smith and Budda were charged after a January 2002 police raid on a business operating as a "compassion club." PMID:15812915

  9. Using Digital Classrooms to Conduct 4-H Club Meetings

    ERIC Educational Resources Information Center

    West, Patricia; Fuhrman, Nicholas E.; Morgan, A. Christian; Duncan, Dennis W.

    2012-01-01

    Using computer technology and digital classrooms to conduct 4-H Club meetings is an efficient way to continue delivering quality 4-H programming during times of limited resources and staff. Nineteen Junior and Senior 4-H'ers participated in seven digital classroom workshops using the Wimba Classroom application. These digital classroom…

  10. Argonne Director Eric Isaacs addresses the National Press Club

    SciTech Connect

    Eric Isaccs

    2009-09-17

    Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

  11. The Secret Club Project: Exploring Miscarriage through the Visual Arts.

    ERIC Educational Resources Information Center

    Seftel, Laura

    2001-01-01

    Examines art as a means to understand the physical and emotional loss of miscarriage. "The Secret Club Project," an innovative exhibit featuring 10 women artists' visual responses to miscarriage, is described. Rituals related to pregnancy loss are reviewed, as well as artists' and art therapists' use of the creative process to move through grief.…

  12. After School Astronomy Clubs: Lessons Learned from Over 10 Years of Collaboration

    NASA Astrophysics Data System (ADS)

    Mayo, Louis

    2010-10-01

    After School Astronomy clubs are unique in focusing on children in the K-12 grades as opposed to the numerous Amateur Astronomy Clubs within the US and abroad whose membership is largely adult focused. Over the last 12 years, we have identified over 100 clubs that were previously running in isolation, provided them with science and education resources and a means to communicate, created an online community of after School Astronomy Clubs, and facilitated the development of new clubs. Over this time, our model for developing and running these clubs has changed as we gained experience with various target populations, educational settings, and external partners and as best practices have emerged regarding engagement, impact, pedagogy, and sustainability. This talk will highlight these experiences and practices and discuss implications for future development of the After School Astronomy Club program.

  13. Evaluation of OAS Education Journals.

    ERIC Educational Resources Information Center

    Leavitt, Howard B.; And Others

    An in-depth evaluation of four Organization of American States educational journals is presented. The journals, published for distribution among Latin American countries, were "Tecnologia Educativa", "Curriculum", "Educacion de Adultors", and "La Educacion". Assessment was made of the journals' mandates, implementation procedures, and managerial…

  14. Journalism in a Free Society.

    ERIC Educational Resources Information Center

    Edwards, Verne E., Jr.

    Broadcast and print journalism are interrelated in this book's coverage of the functions and status of the "fourth estate". A first part discusses journalism's magnitude and significance, with separate chapters offering a profile of the press, a discussion of the people's need to know, and a brief history of American journalism. The second part…

  15. Comparing the Effects of Whey Extract and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on Enamel Microhardness

    PubMed Central

    Rezvani, Mohammad Bagher; Karimi, Mehrdad; Akhavan Rasoolzade, Raheleh; Haghgoo, Roza

    2015-01-01

    Statement of the Problem With the recent focus of researches on the development of non-invasive treatment modalities, the non-invasive treatment of early carious lesions by remineralization would bring a major advance in the clinical management of these dental defects. Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is considered to be effective in tooth remineralization. Purpose The aim of this in-vitro study was to compare the effects of whey and CPP-ACP in increasing the enamel microhardness. Materials and Method Microhardness of 30 sound human permanent premolars was measured before and after 8-minute immersion of samples in Coca-Cola. The teeth were then randomly divided into 3 groups and were immersed in artificial saliva, whey, and tooth mousse for 10 minutes. The changes of microhardness within each group and among the groups were recorded and analyzed using paired t-test. Results The microhardness increased in each group and between the groups; this increase was statistically significant (p= 0.009). Conclusion The effect of whey on increasing the enamel microhardness was more than that of tooth mousse. PMID:25759858

  16. Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

    PubMed Central

    2013-01-01

    3-Oxo-acyl-acyl carrier protein (ACP) reductase (FabG) plays a key role in the bacterial fatty acid synthesis II system in pathogenic microorganisms, which has been recognized as a potential drug target. FabG catalyzes reduction of a 3-oxo-acyl-ACP intermediate during the elongation cycle of fatty acid biosynthesis. Here, we report gene deletion experiments that support the essentiality of this gene in P. aeruginosa and the identification of a number of small molecule FabG inhibitors with IC50 values in the nanomolar to low micromolar range and good physicochemical properties. Structural characterization of 16 FabG-inhibitor complexes by X-ray crystallography revealed that the compounds bind at a novel allosteric site located at the FabG subunit–subunit interface. Inhibitor binding relies primarily on hydrophobic interactions, but specific hydrogen bonds are also observed. Importantly, the binding cavity is formed upon complex formation and therefore would not be recognized by virtual screening approaches. The structure analysis further reveals that the inhibitors act by inducing conformational changes that propagate to the active site, resulting in a displacement of the catalytic triad and the inability to bind NADPH. PMID:24015914

  17. In silico analysis and modeling of ACP-MIP–PilQ chimeric antigen from Neisseria meningitidis serogroup B

    PubMed Central

    Gholami, Mehrdad; Salimi Chirani, Alireza; Moshiri, Mona; Sedighi, Mansour; Pournajaf, Abazar; Tohidfar, Masoud; Irajian, Gholamreza

    2015-01-01

    Background: Neisseria meningitidis, a life-threatening human pathogen with the potential to cause large epidemics, can be isolated from the nasopharynx of 5–15% of adults. The aim of the current study was to evaluate biophysical and biochemical properties and immunological aspects of chimeric acyl-carrier protein-macrophage infectivity potentiator protein-type IV pilus biogenesis protein antigen (ACP-MIP-PilQ) from N. meningitidis serogroup B strain. Methods: Biochemical properties and multiple alignments were predicted by appropriate web servers. Secondary molecular structures were predicted based on Chou and Fasman, Garnier-Osguthorpe-Robson, and Neural Network methods. Tertiary modeling elucidated conformational properties of the chimeric protein. Proteasome cleavage and transporter associated with antigen processing (TAP) binding sites, and T- and B-cell antigenic epitopes, were predicted using bioinformatic web servers. Results: Based on our in silico and immunoinformatics analyses, the ACP-MIP-PilQ protein (AMP) can induce high-level cross-strain bactericidal activity. In addition, several immune proteasomal cleavage sites were detected. The 22 epitopes associated with MHC class I and class II (DR) alleles were confirmed in the AMP. Thirty linear B-cell epitopes as antigenic regions were predicted from the full-length protein. Conclusion: All predicted properties of the AMP indicate it could be a good candidate for further immunological in vitro and in vivo studies. PMID:26989750

  18. Predictors of experiencing aggression in clubs: Beyond alcohol consumption

    PubMed Central

    Miller, Brenda A.; Bourdeau, Beth; Johnson, Mark; Voas, Robert

    2014-01-01

    To examine the social drinking group's influence on the individual's experiences of physical or sexual aggression at clubs, data were collected from 368 groups (N=986 individuals). Both group and individual level indicators were examined for impact on self-reports of physical and sexual aggression experiences while at the club. Recent aggressive experiences and perpetration, concerns for group safety, one's own plans and assessment of other group members' plans to drink to the point of intoxication, and personal characteristics were examined, using both individual and group indicators. At exit, participants reported experiencing physical aggression (12.3%) and sexual aggression (12.6%) at the club. Using generalized linear mixed modeling to account for nested data (club, event, and group), group level indicators predicted both the individual's physical and sexual aggression experiences. Especially for experiences of physical aggression, group effects are notable. Being in a group whose members recently experienced physical aggression, increased the risk for the individual. Interestingly, groups that had higher levels of planned intoxication decreased risks of experiencing aggression, while a discrepancy in these intentions among group members increased the risks. Group effects were also noted for experiencing sexual aggression. High levels of prior experiences for sexual aggression in the group increased the risks for the individual during the event. Also, being in a group that is identified as having at least one member who is frequently drunk, increases the risk for experiencing sexual aggression. These findings inform prevention strategies for young adults engaged in high risk behaviors by targeting social drinking groups who frequent clubs. PMID:24838821

  19. History society launches journal

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    A fledgling international organization plans to launch, in the next few months, a journal devoted to the study of the history of the earth sciences. The journal, to be published by the History of Earth Sciences Society (HESS), will be edited by Gerald M. Friedman ot the Rensselaer Polytechnic Institute.HESS will promote interest and scholarship in the history of the earth sciences by publishing the semiannual journal, by organizing meetings about the history of earth sciences, and by supporting the efforts of other associations displaying similar interests, according to the society's draft constitution. An organizational meeting to ratify the constitution and to elect officers will be held in conjunction with the annual meeting of the Geological Society of America in October. The interim officers and the proposed slate for 1983 include David B. Kitts (University of Oklahoma, Norman), president; Albert V. Carrozi (University of Illinois, Urbana), president-elect; and Ellis L. Yochelson (U.S. Geological Survey, National Museum of Natural History), secretary.

  20. Journal Self-Citedness in "Journal Citation Reports" Library and Information Science and Genetics Journal Rankings.

    ERIC Educational Resources Information Center

    Nisonger, Thomas E.

    1998-01-01

    Investigates the effect of journal self-citedness on "Journal Citation Reports" (JCR) rankings of library and information science and genetics journals using data from 1994 on CD-ROM. Results for library and information science indicate that the effect of self-citedness on both JCR impact factor and total citation rankings was minimal. (Author/AEF)

  1. Algorithmic Procedure for Finding Semantically Related Journals.

    ERIC Educational Resources Information Center

    Pudovkin, Alexander I.; Garfield, Eugene

    2002-01-01

    Using citations, papers and references as parameters a relatedness factor (RF) is computed for a series of journals. Sorting these journals by the RF produces a list of journals most closely related to a specified starting journal. The method appears to select a set of journals that are semantically most similar to the target journal. The…

  2. The Journal Microarrays

    PubMed Central

    Lin, Shu-Kun

    2011-01-01

    Our publishing company MDPI AG has its headquarters in Basel, Switzerland where there are thousands of scientists working in the laboratories of pharmaceutical companies and institutes including Novartis [1], F. Hoffmann-La Roche [2] and institutes affiliated with University of Basel [3]. In 1996, the first annual microplate conference MipTec was held in Basel, and the MipTec 2011 was held a few days ago in Basel [4]. I published a paper on microplate standardization presented at MipTec 1996 in MDPI’s longest-running journal Molecules [5-7]. [....

  3. "In the Interest of the Colored Boys": Christopher J. Atkinson, William T. Coleman, and the Extension of Boys' Clubs Services to African-American Communities, 1906-1931

    ERIC Educational Resources Information Center

    Savage, Carter Julian

    2011-01-01

    This paper details how African-American boys' club workers, their Clubs as well as their service to African-American youth, gained legitimacy within the Boys' Club Federation, now Boys & Girls Clubs of America (BGCA). Specifically, it illustrates what facilitated a predominantly urban, northeastern organization to begin opening Clubs for…

  4. eLearning: A Review of Internet-Based Continuing Medical Education

    ERIC Educational Resources Information Center

    Wutoh, Rita; Boren, Suzanne Austin; Balas, E. Andrew

    2004-01-01

    Introduction: The objective was to review the effect of Internet-based continuing medical education (CME) interventions on physician performance and health care outcomes. Methods: Data sources included searches of MEDLINE (1966 to January 2004), CINAHL (1982 to December 2003), ACP Journal Club (1991 to July/August 2003), and the Cochrane Database…

  5. Reflective journaling: developing an online journal for distance education.

    PubMed

    Kessler, Penny D; Lund, Carole H

    2004-01-01

    Reflective journal writing can be a useful heuristic tool to foster critical thinking skills and develop reflective clinical practice in nursing. When combined with a distance education delivery format, the online journal helps to leverage the strengths of reflective learning with educational technology as well as provide a seamless record of learning outcomes across the curriculum. The authors discuss the incorporation of an online reflective journal into a distance education clinical course and provide guidelines for educators considering a similar approach.

  6. Literature circles book club for science and language arts

    NASA Astrophysics Data System (ADS)

    Bombard, Britain

    Students from an urban middle school participated in a Science Book Club for one semester using the literature circles format. These students voluntarily attended twice weekly lunch meetings, reading books that followed their Grade 7 science classes. Groups of three to six participants read the same text, each performing rotating jobs to improve group discussions during meetings. When a group completed a book, participants created a presentation to share what they learned with the other groups in the club and the researcher/teacher. This research measured gains in science content knowledge and language arts skills focusing on reading comprehension, and literary response and analysis. Gains were measured using pre-existing district benchmarks. An ANCOVA showed that while no gains were found in science content knowledge, there were gains in language arts in the areas of reading comprehension and literary response and analysis.

  7. Managing and promoting change: implementing the Leg Club model.

    PubMed

    Seymour, Ellen

    2005-09-01

    Patient knowledge of their disease may increase concordance to compression therapy. The Lindsay Leg Club model (Lindsay, 2004) empowers the community nursing team to truly get to know their communities and deliver local, high-quality, evidence-based care for patients with leg ulcers and leg related problems. The author's experience of opening a Leg Club has lead to changes in clinical practice: re-evaluation of the use of long stretch bandages in favour of short stretch; replacing conventional compression bandage systems with two piece graduated compression hosiery; increased patient concordance post healing with increased use of compression hosiery; the introduction of toe bandaging and appropriate long-term management for those patients with lymphoedema; and developing the role of the nursing auxiliary in leg ulcer care.

  8. The Supernova Club: Bringing Space Science to Urban Youths

    NASA Astrophysics Data System (ADS)

    Sakimoto, P. J.; Pettit, R.; Balsara, D.; Garnavich, P.

    2008-06-01

    The Supernova Club is an experiment aimed at bringing space science to youths, almost all African Americans, from the most severely disadvantaged areas of the South Bend, Indiana, region. It leverages the National Youth Sports Program (NYSP) that, in Summer 2007, brought 100 children, ages 10-16 and living at or below the poverty level, to the Notre Dame campus for a 4-week non-residential summer program. Six contact hours of space science instruction were added to the core curriculum of nutrition, physical fitness, and academic study. At summer's end, 13 high interest/high potential youths were selected to form ``The Supernova Club''-a year-round, after-school, weekly follow-up program.

  9. Cloning of acyl-ACP thioesterase FatA from Arachis hypogaea L. and its expression in Escherichia coli.

    PubMed

    Chen, Gao; Peng, Zhen-ying; Shan, Lei; Xuan, Ning; Tang, Gui-ying; Zhang, Yan; Li, Lan; He, Qing-fang; Bi, Yu-ping

    2012-01-01

    In this study, a full-length cDNA of the acyl-ACP thioesterase, AhFatA, was cloned from developing seeds of Arachis hypogaea L. by 3'-RACE. Sequence analysis showed that the open reading frame encodes a peptide of 372 amino acids and has 50-70% identity with FatA from other plants. Real-time quantitative PCR analysis revealed that AhFatA was expressed in all tissues of A. hypogaea L., but most strongly in the immature seeds harvested at 60 days after pegging. Heterologous expression of AhFatA in Escherichia coli affected bacterial growth and changed the fatty acid profiles of the membrane lipid, resulting in directed accumulation towards palmitoleic acid and oleic acid. These results indicate that AhFatA is at least partially responsible for determining the high palmitoleic acid and oleic acid composition of E. coli.

  10. Cloning of Acyl-ACP Thioesterase FatA from Arachis hypogaea L. and Its Expression in Escherichia coli

    PubMed Central

    Chen, Gao; Peng, Zhen-ying; Shan, Lei; Xuan, Ning; Tang, Gui-ying; Zhang, Yan; Li, Lan; He, Qing-fang; Bi, Yu-ping

    2012-01-01

    In this study, a full-length cDNA of the acyl-ACP thioesterase, AhFatA, was cloned from developing seeds of Arachis hypogaea L. by 3′-RACE. Sequence analysis showed that the open reading frame encodes a peptide of 372 amino acids and has 50–70% identity with FatA from other plants. Real-time quantitative PCR analysis revealed that AhFatA was expressed in all tissues of A. hypogaea L., but most strongly in the immature seeds harvested at 60 days after pegging. Heterologous expression of AhFatA in Escherichia coli affected bacterial growth and changed the fatty acid profiles of the membrane lipid, resulting in directed accumulation towards palmitoleic acid and oleic acid. These results indicate that AhFatA is at least partially responsible for determining the high palmitoleic acid and oleic acid composition of E. coli. PMID:23093853

  11. QSAR and Molecular Docking Studies of Oxadiazole-Ligated Pyrrole Derivatives as Enoyl-ACP (CoA) Reductase Inhibitors

    PubMed Central

    Asgaonkar, Kalyani D.; Mote, Ganesh D.; Chitre, Trupti S.

    2014-01-01

    A quantitative structure-activity relationship model was developed on a series of compounds containing oxadiazole-ligated pyrrole pharmacophore to identify key structural fragments required for anti-tubercular activity. Two-dimensional (2D) and three-dimensional (3D) QSAR studies were performed using multiple linear regression (MLR) analysis and k-nearest neighbour molecular field analysis (kNN-MFA), respectively. The developed QSAR models were found to be statistically significant with respect to training, cross-validation, and external validation. New chemical entities (NCEs) were designed based on the results of the 2D- and 3D-QSAR. NCEs were subjected to Lipinski’s screen to ensure the drug-like pharmacokinetic profile of the designed compounds in order to improve their bioavailability. Also, the binding ability of the NCEs with enoyl-ACP (CoA) reductase was assessed by docking. PMID:24634843

  12. Campylobacter jejuni fatty acid synthase II: Structural and functional analysis of [beta]-hydroxyacyl-ACP dehydratase (FabZ)

    SciTech Connect

    Kirkpatrick, Andrew S.; Yokoyama, Takeshi; Choi, Kyoung-Jae; Yeo, Hye-Jeong

    2009-08-14

    Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making FAS II enzymes excellent targets for antibiotics discovery. The {beta}-hydroxyacyl-ACP dehydratase (FabZ) catalyzes an essential step in the FAS II pathway. Here, we report the structure of Campylobacter jejuni FabZ (CjFabZ), showing a hexamer both in crystals and solution, with each protomer adopting the characteristic hot dog fold. Together with biochemical analysis of CjFabZ, we define the first functional FAS II enzyme from this pathogen, and provide a framework for investigation on roles of FAS II in C. jejuni virulence

  13. X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv

    SciTech Connect

    Dyer, David H.; Lyle, Karen S.; Rayment, Ivan; Fox, Brian G.

    2010-07-13

    Genome sequencing showed that two proteins in Mycobacterium tuberculosis H37Rv contain the metal binding motif (D/E)X{sub 2}HX{sub {approx}100}(D/E)X{sub 2}H characteristic of the soluble diiron enzyme superfamily. These putative acyl-ACP desaturase genes desA1 and desA2 were cloned from genomic DNA and expressed in Escherichia coli BL21(DE3). DesA1 was found to be insoluble, but in contrast, DesA2 was a soluble protein amenable to biophysical characterization. Here, we report the 2.0 {angstrom} resolution X-ray structure of DesA2 determined by multiple anomalous dispersion (MAD) phasing from a Se-met derivative and refinement against diffraction data obtained on the native protein. The X-ray structure shows that DesA2 is a homodimeric protein with a four-helix bundle core flanked by five additional helices that overlay with 192 structurally equivalent amino acids in the structure of stearoyl-ACP {Delta}9 desaturase from castor plant with an rms difference 1.42 {angstrom}. In the DesA2 crystals, one metal (likely Mn from the crystallization buffer) was bound in high occupancy at the B-site of the conserved metal binding motif, while the A-site was not occupied by a metal ion. Instead, the amino group of Lys-76 occupied this position. The relationships between DesA2 and known diiron enzymes are discussed.

  14. Early-onset obesity and paternal 2pter deletion encompassing the ACP1, TMEM18, and MYT1L genes

    PubMed Central

    Doco-Fenzy, Martine; Leroy, Camille; Schneider, Anouck; Petit, Florence; Delrue, Marie-Ange; Andrieux, Joris; Perrin-Sabourin, Laurence; Landais, Emilie; Aboura, Azzedine; Puechberty, Jacques; Girard, Manon; Tournaire, Magali; Sanchez, Elodie; Rooryck, Caroline; Ameil, Agnès; Goossens, Michel; Jonveaux, Philippe; Lefort, Geneviève; Taine, Laurence; Cailley, Dorothée; Gaillard, Dominique; Leheup, Bruno; Sarda, Pierre; Geneviève, David

    2014-01-01

    Obesity is a common but highly, clinically, and genetically heterogeneous disease. Deletion of the terminal region of the short arm of chromosome 2 is rare and has been reported in about 13 patients in the literature often associated with a Prader–Willi-like phenotype. We report on five unrelated patients with 2p25 deletion of paternal origin presenting with early-onset obesity, hyperphagia, intellectual deficiency, and behavioural difficulties. Among these patients, three had de novo pure 2pter deletions, one presented with a paternal derivative der(2)t(2;15)(p25.3;q26) with deletion in the 2pter region and the last patient presented with an interstitial 2p25 deletion. The size of the deletions was characterized by SNP array or array-CGH and was confirmed by fluorescence in situ hybridization (FISH) studies. Four patients shared a 2p25.3 deletion with a minimal critical region estimated at 1.97 Mb and encompassing seven genes, namely SH3HYL1, ACP1, TMEMI8, SNTG2, TPO, PXDN, and MYT1L genes. The fifth patient had a smaller interstitial deletion encompassing the TPO, PXDN, and MYT1L genes. Paternal origin of the deletion was determined by genotyping using microsatellite markers. Analysis of the genes encompassed in the deleted region led us to speculate that the ACP1, TMEM18, and/or MYT1L genes might be involved in early-onset obesity. In addition, intellectual deficiency and behavioural troubles can be explained by the heterozygous loss of the SNTG2 and MYT1L genes. Finally, we discuss the parent-of-origin of the deletion. PMID:24129437

  15. Early-onset obesity and paternal 2pter deletion encompassing the ACP1, TMEM18, and MYT1L genes.

    PubMed

    Doco-Fenzy, Martine; Leroy, Camille; Schneider, Anouck; Petit, Florence; Delrue, Marie-Ange; Andrieux, Joris; Perrin-Sabourin, Laurence; Landais, Emilie; Aboura, Azzedine; Puechberty, Jacques; Girard, Manon; Tournaire, Magali; Sanchez, Elodie; Rooryck, Caroline; Ameil, Agnès; Goossens, Michel; Jonveaux, Philippe; Lefort, Geneviève; Taine, Laurence; Cailley, Dorothée; Gaillard, Dominique; Leheup, Bruno; Sarda, Pierre; Geneviève, David

    2014-04-01

    Obesity is a common but highly, clinically, and genetically heterogeneous disease. Deletion of the terminal region of the short arm of chromosome 2 is rare and has been reported in about 13 patients in the literature often associated with a Prader-Willi-like phenotype. We report on five unrelated patients with 2p25 deletion of paternal origin presenting with early-onset obesity, hyperphagia, intellectual deficiency, and behavioural difficulties. Among these patients, three had de novo pure 2pter deletions, one presented with a paternal derivative der(2)t(2;15)(p25.3;q26) with deletion in the 2pter region and the last patient presented with an interstitial 2p25 deletion. The size of the deletions was characterized by SNP array or array-CGH and was confirmed by fluorescence in situ hybridization (FISH) studies. Four patients shared a 2p25.3 deletion with a minimal critical region estimated at 1.97 Mb and encompassing seven genes, namely SH3HYL1, ACP1, TMEMI8, SNTG2, TPO, PXDN, and MYT1L genes. The fifth patient had a smaller interstitial deletion encompassing the TPO, PXDN, and MYT1L genes. Paternal origin of the deletion was determined by genotyping using microsatellite markers. Analysis of the genes encompassed in the deleted region led us to speculate that the ACP1, TMEM18, and/or MYT1L genes might be involved in early-onset obesity. In addition, intellectual deficiency and behavioural troubles can be explained by the heterozygous loss of the SNTG2 and MYT1L genes. Finally, we discuss the parent-of-origin of the deletion.

  16. A functional analysis of ACP-20, an adult-specific cuticular protein gene from the beetle Tenebrio: role of an intronic sequence in transcriptional activation during the late metamorphic period.

    PubMed

    Lemoine, A; Mathelin, J; Braquart-Varnier, C; Everaerts, C; Delachambre, J

    2004-10-01

    A gene encoding the adult cuticular protein ACP-20 was isolated in Tenebrio. It consists of three exons interspersed by two introns, intron 1 interrupting the signal peptide. To understand the regulatory mechanisms of ACP-20 expression, ACP-20 promoter-luciferase reporter gene constructs were transfected into cultured pharate adult wing epidermis. Transfection assays needed the presence of 20-hydroxyecdysone, confirming that ACP-20 is up-regulated by ecdysteroids. Analysis of 5' deletion constructs revealed that three regions are necessary for high levels of transcription. Interaction experiments between intronic fragments and epidermal nuclear proteins confirmed the importance of intron 1 in ACP-20 transcriptional control, which results from the combined activity of regulatory cis-acting elements of the promoter and those of intron 1.

  17. Mothers in community health care activities: the Suita Mothers' Club. Part 2.

    PubMed

    Nishiuchi, M

    1985-01-01

    Trachoma was widespread in Japan in the early 1950s. In February of 1952 the Suita Mothers' Club started its checkup campaign for the prevention of trachoma. When the club was formed there were many flies and mosquitos throughout the city. Both flies and mosquitos carry or spread dangerous diseases. The Club began thinking seriously about the extermination of these insects. Additionally, one of the dampest areas in the city was selected as a model area for pest eradication. A 5-year plan was designed. The plan included cleaning up of family homes and vacant lots. The Suita Mothers' Club was also responsible for a program to strike out tuberculosis, as well as a program to prevent cerebral apoplexy. The Club has lasted about 35 years. It publishes a newsletter every month. Club members believe it is important to think as a group and act as a group.

  18. Drink-driving in community sports clubs: adopting the Good Sports alcohol management program.

    PubMed

    Rowland, Bosco; Toumbourou, John; Allen, Felicity

    2012-09-01

    Throughout the developed world, community sports clubs are a high-risk setting for alcohol-impaired driving. The Good Sports program accredits community sports clubs to encourage implementation of alcohol-focussed harm-reduction and safe-transport strategies. This study tested for associations between participation in the Good Sports program and reduced rates of drink-driving amongst club members. Multilevel modelling indicated that for each season a club was in the program there was an 8% reduction in the odds of drink-driving. These findings may arise due to clubs with lower rates of alcohol use maintaining longer involvement in the program. However, the findings are also compatible with the intention of the Good Sports program to reduce the risk that club members will drive whilst alcohol impaired.

  19. SciTech Clubs for Girls. [Annual] technical report

    SciTech Connect

    Nogal, A.M.

    1993-02-01

    Since January 1992, 9 exhibits have been constructed by the SciTech Clubs for Girls, which involved 63 girls, ages 10 to 14. These exhibits are: Bubble Shapes by the St. Charles Cadette Girl Scout Troop No. 109. Density Games by the South Elgin Cadette Girl Scout Troop No. 132. Electric Fleas by the Warrenville Junior Girl Scout Troop No. 305. Energy vs. Power by the Aurora Junior Girl Scout Troop No. 242. The Organ Pipe by the Bartlett Junior Girl Scout Troop No. 107. Ohm`s Law by the Geneva Junior Girl Scout Troop No. 401. What is Gravity by the Pilsen YMCA girls. Insulation at Work by the Algonquin Junior Girl Scout Troop No. 303. Series vs. Parallel by the Leland Junior Girl Scout Troop No. 50. The report is a description of each exhibit and the group that built the exhibit. Each group had a minimum of 10 hours of contact time at SciTech with the SciTech Clubs for Girls Program Coordinator. All mentors are female. Each exhibit building experience includes a trip to the hardware store to purchase supplies. After the exhibit is complete, the girls receive certificates of achievement and a SciTech Club Patch.

  20. [Club drugs: old medicines as new party drugs].

    PubMed

    Abanades, Sergio; Peiró, Ana M; Farré, Magí

    2004-09-11

    During the last few years the term club drugs has been used for defining an heterogeneous group of chemical substances in permanent evolution, that are consumed for recreational purposes. These substances have been extensively used, firstly by the Rave culture and later by the so called Club culture. These movements are characterized by the search of amplified sensations, by means of the combination of electronic music, marathon dancing and substance abuse. After years with a predominating consumption of designer amphetamines in these groups, it seems that the use of another type of substances is increasing, fundamentally drugs with hallucinogenic effects. This review focus in four of these substances; ketamine, dextromethorphan, nitrous oxide and gamma-hydroxybutyric acid (GHB, liquid ecstasy), and includes a discussion of their pharmacology, recreational use, adverse effects and patient management. These drugs are, at he same time, drugs of abuse and medicines with concrete indications in therapeutics, with an important increase of their consumption in the last few years. The Rave and Club cultures are also described.

  1. Practical Ideas for Teaching Journalism.

    ERIC Educational Resources Information Center

    Bustrum, Dwight, Ed.; Hallenbeck, Carol, Ed.; Rittger, Alison, Ed.

    A "how-to" book for advisers looking for creative and contemporary ways to teach journalism, this book can be a single source for a journalism class or a supplement to any high school journalism text. The book concentrates on teaching methods as well as subject matter--it tells teachers what to do and how to do it, what to say and what to write on…

  2. Effect of a mutagenized acyl-ACP thioesterase FATA allele from sunflower with improved activity in tobacco leaves and Arabidopsis seeds.

    PubMed

    Moreno-Pérez, Antonio Javier; Venegas-Calerón, Mónica; Vaistij, Fabián E; Salas, Joaquin J; Larson, Tony R; Garcés, Rafael; Graham, Ian A; Martínez-Force, Enrique

    2014-03-01

    The substrate specificity of the acyl-acyl carrier protein (ACP) thioesterases significantly determines the type of fatty acids that are exported from plastids. Thus, designing acyl-ACP thioesterases with different substrate specificities or kinetic properties would be of interest for plant lipid biotechnology to produce oils enriched in specialty fatty acids. In the present work, the FatA thioesterase from Helianthus annuus was used to test the impact of changes in the amino acids present in the binding pocket on substrate specificity and catalytic efficiency. Amongst all the mutated enzymes studied, Q215W was especially interesting as it had higher specificity towards saturated acyl-ACP substrates and higher catalytic efficiency compared to wild-type H. annuus FatA. Null, wild type and high-efficiency alleles were transiently expressed in tobacco leaves to check their effect on lipid biosynthesis. Expression of active FatA thioesterases altered the composition of leaf triacylglycerols but did not alter total lipid content. However, the expression of the wild type and the high-efficiency alleles in Arabidopsis thaliana transgenic seeds resulted in a strong reduction in oil content and an increase in total saturated fatty acid content. The role and influence of acyl-ACP thioesterases in plant metabolism and their possible applications in lipid biotechnology are discussed.

  3. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2009-2010 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2010

    2010-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its five staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by Commissioners…

  4. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2006-2007 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2007

    2007-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5 year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its eight staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  5. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2008-2009 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2009

    2009-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its eight staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  6. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2007-2008 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2008

    2008-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its nine staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by …

  7. Morphological and metabolic changes in transgenic wheat with altered glycerol-3-phosphate acyltransferase or acyl-acyl carrier protein (ACP) thioesterase activities.

    PubMed

    Edlin, D A; Kille, P; Wilkinson, M D; Jones, H D; Harwood, J L

    2000-12-01

    We have transformed varieties of wheat with a Pisum sativum glycerol-3-phosphate acyltransferase gene, and also with an Arabidopsis thaliana acyl-ACP thioesterase gene. Morphological (growth, organelle development) and metabolic changes (fatty acid labelling of chloroplast and non-chloroplast lipids) have been observed in transgenics with altered gene expression for either enzyme. PMID:11171169

  8. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. Arizona Commission for Postsecondary Education (ACPE) Fiscal Year 2005-2006 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2006

    2006-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its seven staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  9. Club foot, an adverse outcome of early amniocentesis: disruption or deformation?

    PubMed Central

    Farrell, S; Summers, A; Dallaire, L; Singer, J; Johnson, J.; Wilson, R

    1999-01-01

    An association between the occurrence of club foot and early amniocentesis has been reported. The largest of these randomised studies was the Canadian Early and Mid-Trimester Amniocentesis Trial. Data describing the neonatal outcome, focusing on this association, are presented. Possible mechanisms for the association and the implications for the development of club foot are discussed.


Keywords: amniocentesis; early amniocentesis; club foot PMID:10544229

  10. Nineteenth Century Medical Journalism in Texas: With a Journal Checklist *

    PubMed Central

    Baird, Violet M.

    1972-01-01

    Texas medical journals prior to 1900 have been incompletely (sometimes incorrectly) recorded in periodical checklists. This paper attempts to provide a short account of the purposes and achievements of the more significant journals and to list all names and related name changes, in so far as it has been possible to do so. PMID:4559906

  11. Style in medical journals.

    PubMed Central

    Adams Smith, D E

    1983-01-01

    A study of medical journals from 1962 showed a constant preoccupation with style. Editors and contributors on both sides of the Atlantic revile unnecessary obscurity and complexity and the use of jargon, barbarisms, vogue words, and weak impersonal constructions. They bewail the pompous use of verbiage and the "medspeak" typified by acronyms and neologisms created by affixation. Suggestions for possible causes of poor medical style range from editorial demands for compression and a general ignorance of the principles of good writing to faulty logic and the subordination of communication to status seeking. The consequences of bad writing may include the fragmentation of knowledge, an increase in the importance of abstracting services, a trend towards free glossy medical newspapers, and, as remedial measures, workshops and courses in medical writing. Some implications for English language teachers working with foreign medical graduates and preclinical students are discussed. PMID:6414596

  12. The youth sports club as a health-promoting setting: An integrative review of research

    PubMed Central

    Quennerstedt, Mikael; Eriksson, Charli

    2013-01-01

    Aims: The aims of this review is to compile and identify key issues in international research about youth sports clubs as health-promoting settings, and then discuss the results of the review in terms of a framework for the youth sports club as a health-promoting setting. Methods: The framework guiding this review of research is the health-promoting settings approach introduced by the World Health Organization (WHO). The method used is the integrated review. Inclusion criteria were, first, that the studies concerned sports clubs for young people, not professional clubs; second, that it be a question of voluntary participation in some sort of ongoing organized athletics outside of the regular school curricula; third, that the studies consider issues about youth sports clubs in terms of health-promoting settings as described by WHO. The final sample for the review consists of 44 publications. Results: The review shows that youth sports clubs have plentiful opportunities to be or become health-promoting settings; however this is not something that happens automatically. To do so, the club needs to include an emphasis on certain important elements in its strategies and daily practices. The youth sports club needs to be a supportive and healthy environment with activities designed for and adapted to the specific age-group or stage of development of the youth. Conclusions: To become a health-promoting setting, a youth sports club needs to take a comprehensive approach to its activities, aims, and purposes. PMID:23349167

  13. The PIP training programme: building of ACP experts capacities in crop protection and food safety to support local companies to comply with EU regulations on pesticides residues.

    PubMed

    Schiffers, B C; Schubert, A; Schiffers, C; Fontaine, S; Gumusboga, N; Werner, B; Webb, M; Lugros, H; Stinglhamber, G

    2006-01-01

    Regulatory requirements, and in particular phytosanitary quality standards change rapidly. As ACP producers/exporters race to become more competitive, to keep their market share and to satisfay their customers' commercial demands (e.g. EUREP-GAP certification), the need for competent staff who are aware of the company's quality objectives and trained to follow instructions is crucial. Mastering sanitary quality is only possible if matched with a programme to build the skills of companies' human resources. The Pesticide Initiative Programme (PIP), mindful of the importance of making operators autonomous and of training them to monitor EU food safety regulations and technology on their own, has successfully developed a training programme while building a quality network of local/ACP service providers. By building the capacities of ACP experts and then securing their services as trainers, PIP also guarantees companies' access to expertise and the sustainability of their efforts to comply with new EU regulations. The training strategy developed by PIP rests on two pilars: instructor training and collective training. Instructor training consists in reinforcing the technical knowledge of local experts (agronomists, hygienists, etc.) by providing them with active teaching methods. Once the ACP experts have gained enough technical knowledge of the key areas of crop protection--mainly pesticides management--and food safety, and have demonstrated their capacity to train the technical staff of local companies, the PIP has carried out a collective training programme in 2004, 2005 and 2006. To date, more than 130 consultants covering about 15 ACP countries have received instructor training, and more than 700 people have participated in collective and in-company training sessions.

  14. A Patient Representative Inservice Journal.

    ERIC Educational Resources Information Center

    Garrison, Shirley; And Others

    This inservice journal is a diary of the inservice programs that were held in 1982-1983 for volunteers and paid staff working in the patient relations department at Highland Park Hospital in Highland Park, Illinois. The first section of the journal contains a list of the purposes of inservice education. Summarized next are individual inservice…

  15. THE Journal's 2007 Innovators: 1

    ERIC Educational Resources Information Center

    T.H.E. Journal, 2007

    2007-01-01

    Through a variety of efforts large and small, across schools, districts, and even oceans, educators are making teaching and learning alive through the pioneering use of technology. Together, they are "T.H.E. Journal"'s class of 2007 Innovators. This article presents the class of 2007 Innovators along with their profiles. They are: (1) Edith…

  16. Journalism and Institutional Review Boards

    ERIC Educational Resources Information Center

    Dash, Leon

    2007-01-01

    The author opposes any Institutional Review Boards (IRBs) overseeing the work of journalism professors and journalism students in any academic institution. He argues that the tendency for IRBs to require anonymity for persons interviewed immediately reduces the credibility of any journalistic story. The composition of an IRB is questioned on…

  17. Japan Studies Association Journal, 1998.

    ERIC Educational Resources Information Center

    Speaker, Richard B., Jr., Ed.; Kawada, Louise Myers, Ed.

    1998-01-01

    This journal presents new perspectives and materials on Japan that are engaging, relatively jargon-free, and shaped so that their usefulness in a college classroom is readily apparent. The journal represents an example of the potential for genuine scholarship that lies within interdisciplinary studies. Articles are divided among three thematic…

  18. Creating the Culture of Journalism.

    ERIC Educational Resources Information Center

    Irby, Janet R.

    The high school journalism classroom provides a natural environment for learning in the context of a discipline's culture. This environment can provide the backdrop for moving the student toward the thinking and behavior of professional journalists. To understand this thinking, journalism teachers can turn to the research in cognitive psychology…

  19. Twenty Years of Cultural Journalism.

    ERIC Educational Resources Information Center

    Olmstead, Kathryn J.

    1986-01-01

    Traces history and contributions of cultural journalism since the inception of the first Foxfire Book in 1966. Reviews successful student projects across the country. Discusses significance of cultural journalism as source of cultural identity with potential to increase understanding among different groups of people. (NEC)

  20. Journaling as an Assessment Option

    ERIC Educational Resources Information Center

    James, Alisa

    2005-01-01

    Journaling is a specific assessment tool teachers can use to examine student learning in the affective and cognitive domains. It also provides a nonthreatening venue for students to communicate their knowledge and feelings about physical education. This article examines the use of student journals as an assessment tool in physical education. The…

  1. Humanities Journals Confront Identity Crisis

    ERIC Educational Resources Information Center

    Howard, Jennifer

    2009-01-01

    Senior scholars, the A-list of academic publishing, seem to submit fewer unsolicited manuscripts to traditional humanities journals than they used to. The journal has become, with very few exceptions, the place where junior and midlevel scholars are placing their work. Technology and changing habits have called into question the nature of the…

  2. Journalism. Language Arts Curriculum Guide.

    ERIC Educational Resources Information Center

    Tennessee State Dept. of Education, Nashville.

    As part of the language arts curriculum framework developed in accordance with "Rules, Regulations, and Minimum Standards" of the Tennessee State Board of Education, this journalism curriculum framework contains the goals, concepts, and terminal objectives for journalism courses in grades 9-12. Following an introduction, a description of the…

  3. The Urbanization of American Journalism.

    ERIC Educational Resources Information Center

    Nord, David Paul

    1992-01-01

    Discusses the changes in journalism occurring during the growth of private enterprise in the United States. Focuses on newspapers in Chicago and other midwestern cities. Describes Joseph Pulitzer's "New York World" as the culmination of the urbanization of U.S. journalism, recognizing the development of public interdependence in a private world.…

  4. Let Us Rank Journalism Programs

    ERIC Educational Resources Information Center

    Weber, Joseph

    2014-01-01

    Unlike law, business, and medical schools, as well as universities in general, journalism schools and journalism programs have rarely been ranked. Publishers such as "U.S. News & World Report," "Forbes," "Bloomberg Businessweek," and "Washington Monthly" do not pay them much mind. What is the best…

  5. Ethical considerations in anaesthesia journals.

    PubMed

    Asai, T; Shingu, K

    1999-02-01

    It has been shown that instructions to authors in nonanaesthesia biomedical journals often fail to require authors to state that the study was approved by an ethics committee and informed consent obtained from participants; articles also often omit mentioning these points. We examined 11 English-language journals, which are listed in the 'Anesthesiology' category of 1995 SCI Journal Citation Reports, to see whether the instructions to authors of anaesthesia journals mention the following ethical factors: approval of the study by an ethics committee, informed consent, redundant publication, fraud, authorship, conflict of interest and protection of patients' privacy. We also examined 673 articles which appeared in these anaesthesia journals ( July to December issues of 1996) to see whether they stated acquirement of ethics committee approval and informed consent. All journals addressed the avoidance of redundant publications and unjustifiable authorship. Ten journals required approval of studies and signatures from all authors, eight journals mentioned informed consent. Only seven required the disclosure of any conflict of interest and the protection of patients' privacy. More than 90% of the articles stated that the study was approved and informed consent obtained.

  6. Japan Studies Association Journal, 2001.

    ERIC Educational Resources Information Center

    Reichel, Philip L., Ed.

    2001-01-01

    This journal presents new perspectives and materials on Japan that are engaging, relatively jargon-free, and shaped so that their usefulness in a college classroom is readily apparent. The journal represents an example of the potential for genuine scholarship that lies within interdisciplinary studies. Articles grouped under the topic of "Minority…

  7. Primary Journal Literature of Physics.

    ERIC Educational Resources Information Center

    Cooper, Marianne; Thayer, Candace W.

    Four hundred and ninety one primary journals covered by "Physics Abstracts" in 1965 have been studied and their basic characteristics analyzed in terms of sponsorship, distribution by country, language, frequency, and coverage by secondary services other than "Physics Abstracts," and the number of libraries holding each journal. (Author)

  8. Local Evaluation of Chemistry Journals

    ERIC Educational Resources Information Center

    Kraus, Joseph R.; Hansen, Rachel

    2008-01-01

    This paper reports on the evaluation of local usage statistics of a specific set of chemistry journals at the University of Denver in Colorado, USA. The objective of the study is to demonstrate that commercial publishers in chemistry charge considerably more for their journals than those from the non-commercial sector. There are three variables…

  9. Pacific Educational Research Journal, 1996.

    ERIC Educational Resources Information Center

    Berg, Kathleen F., Ed.; Lai, Morris K., Ed.

    1996-01-01

    This first issue of the new "Pacific Educational Research Journal" offers articles covering diverse subjects and using diverse research methods. The new journal represents a rejuvenation of a previous publication to address educational issues specific to the Pacific region. Ethnic groups specifically addressed include Hawaiians, second-generation…

  10. The Archives of "English Journal."

    ERIC Educational Resources Information Center

    Perrin, Robert

    A perusal of back issues of the "English Journal" since its beginnings in 1912 reveals a sense of continuity in the teaching profession. Over the years, the journal has addressed topics of interest to teachers. Some of these topics, even those from the earliest issues, shed light on current topics in English teaching, including the following: (1)…

  11. Journals with Borders, Journals without Borders: Under-Representation of Asian Countries in Educational Research Journals

    ERIC Educational Resources Information Center

    Atkinson, Roger

    2013-01-01

    As "Australasian Journal of Educational Technology" (AJET) Production Editor, the author evaluates whether AJET is providing a fair and adequate representation for researchers in Asian countries, with particular reference to AJET's aspiration to be "a front ranked international journal with an Australasian character"…

  12. FUTURE OF DERMATOVENEREOLOGICAL JOURNALS1.

    PubMed

    Marinović, Branka

    2016-04-01

    Each year, during the Annual Meeting of the American Academy of Dermatology, there is a meeting of the Council of Dermatology Editors organized by Professor Larry Parish from Philadelphia. It is so nice to meet old friends there and make some new ones, but above all it is a very good platform to discuss the problems journals and their editors are facing today. Some of the topics we discussed during this year's meeting were the increasing number of case reports submitted to all dermatological journals, problems of plagiarism, the rising number of online journals, and the predatory policies quite often connected with them. There was also discussion on print vs online publication versions and on open access journals. It is always useful to discuss common problems, to realize that all journals have similar problems, and to exchange experiences in solving these problems. One of the problems all journals are facing is the increasing number of case reports being submitted, and their high rejection rate due to different reasons. Acta Dermatovenerologica Croatica is overloaded with case reports from many different countries around the world. Most of them are interesting, well prepared cases and could be a good way of exchanging experience between dermatologists. From my personal point of view, case reports are a very useful form of medical communication. For many years they were usually the first articles written by residents under the supervision of their mentors, and I think that all of us should insist on that in the future as well. But the problem is that it has become very difficult to find a journal willing to publish many case reports. Authors are trying to find a journal to publish their case reports in, sometimes sending them to many journals. Unfortunately, the rate of rejection of case reports is rising. And why? There are a few reasons for that, but probably one of the most important is that a high number of published case reports per issue of any journal

  13. Authorship policies of scientific journals

    PubMed Central

    Resnik, David B; Tyle, Ana M; Black, Jennifer R; Kissling, Grace

    2016-01-01

    We analysed the authorship policies of a random sample of 600 journals from the Journal Citation Reports database. 62.5% of the journals we sampled had an authorship policy. Having an authorship policy was positively associated with impact factor. Journals from the biomedical sciences and social sciences/humanities were more likely to have an authorship policy than journals from the physical sciences, engineering or mathematical sciences. Among journals with a policy, the most frequent type of policy was guidance on criteria for authorship (99.7%); followed by guidance on acknowledgments (97.3%); requiring that authors make substantial contributions to the research (94.7%); requiring that authors be accountable for the research as a whole (84.8%); guidance on changes in authorship (77.9%); requiring that authors give final approval to the manuscript (77.6%); requiring that authors draft or critically revise the manuscript (71.7%); providing guidance on corporate authorship (58.9%); prohibiting gift, guest or ghost authorship (31.7%); requiring authors to describe their contributions (5.3%); limiting the number of authors for some types of articles (4.0%) and requiring authors to be accountable for their part in the research (1.1%). None of the policies addressed equal contribution statements. Journals that do not have authorship policies should consider adopting or developing ones. PMID:26714812

  14. Authorship policies of scientific journals.

    PubMed

    Resnik, David B; Tyler, Ana M; Black, Jennifer R; Kissling, Grace

    2016-03-01

    We analysed the authorship policies of a random sample of 600 journals from the Journal Citation Reports database. 62.5% of the journals we sampled had an authorship policy. Having an authorship policy was positively associated with impact factor. Journals from the biomedical sciences and social sciences/humanities were more likely to have an authorship policy than journals from the physical sciences, engineering or mathematical sciences. Among journals with a policy, the most frequent type of policy was guidance on criteria for authorship (99.7%); followed by guidance on acknowledgments (97.3%); requiring that authors make substantial contributions to the research (94.7%); requiring that authors be accountable for the research as a whole (84.8%); guidance on changes in authorship (77.9%); requiring that authors give final approval to the manuscript (77.6%); requiring that authors draft or critically revise the manuscript (71.7%); providing guidance on corporate authorship (58.9%); prohibiting gift, guest or ghost authorship (31.7%); requiring authors to describe their contributions (5.3%); limiting the number of authors for some types of articles (4.0%) and requiring authors to be accountable for their part in the research (1.1%). None of the policies addressed equal contribution statements. Journals that do not have authorship policies should consider adopting or developing ones. PMID:26714812

  15. Science Notes: The Clubbers' Guide--School Biology Clubs

    ERIC Educational Resources Information Center

    Howarth, Sue

    2014-01-01

    The STEM team at the University of Worcester support STEM activities in schools in Herefordshire and Worcestershire. Part of this help includes suggesting activities for STEM clubs. As the biologist on the team author, Sue Howarth was asked by teachers for ideas to use in biology clubs. This article was prompted by feedback that these ideas might…

  16. "The Text Opened My Eyes": A Book Club on Teaching Writing to ELLs

    ERIC Educational Resources Information Center

    Andrei, Elena; Ellerbe, Marcie; Cherner, Todd

    2015-01-01

    This qualitative study looked at a book club for US teachers in public schools focused on teaching writing to English language learners (ELLs). To guide the study, the central research questions were: (1) What are teachers' perceptions about a book club professional development experience?; and (2) How are teachers' views about second language…

  17. Improving Job-Seeking Skills of Adolescents with Handicaps through Job Clubs.

    ERIC Educational Resources Information Center

    Elksnin, Nick; Elksnin, Linda K.

    1988-01-01

    The literature on the effectiveness of "job clubs" as a job-finding technique for handicapped adults was reviewed. The club involves group meetings providing social support from job-seeking peers as well as training in traditional and nontraditional job search methods including networking with friends, relatives, former employers, and other…

  18. Evaluation of Students' Perceptions about Efficiency of Educational Club Practices in Primary Schools

    ERIC Educational Resources Information Center

    Gelen, Ismail; Onay, Ihsan; Varol, Volkan

    2014-01-01

    The purpose of this study is to examine the efficiency of "Educational Club Practices" that has been in Elementary School program since 2005-2006, by examining the attitudes of students about "Educational Club Practices". Sample was selected in two steps. First, stratified sampling was employed and then random sampling was…

  19. Join a Club! Or a Team--Both Can Make Good Citizens

    ERIC Educational Resources Information Center

    Levine, Peter

    2016-01-01

    Sports participation in high school has positive effects on students' later civic engagement. But that is true of nearly all forms of extracurricular participation in high school--whether a group is explicitly civic (student government or a service club) or far removed from civic life (an academic club or a music group). Indeed, the civic…

  20. Experiential Learning for Preservice Teachers: Digital Book Clubs with Third Graders

    ERIC Educational Resources Information Center

    Stover, Katie; Yearta, Lindsay; Harris, Caroline

    2016-01-01

    This study explored how preservice teachers' knowledge and pedagogy is enhanced through participation of online book clubs with third graders. Qualitative data included pre/post interviews, reflection papers, and blog posts of book club conversations, which were all collected and analyzed. Holistic, in-depth exploration of the recurring themes and…

  1. Challenges in Offering Inner-City After-School Physical Activity Clubs

    ERIC Educational Resources Information Center

    Maljak, Kimberly; Garn, Alex; McCaughtry, Nate; Kulik, Noel; Martin, Jeffrey; Shen, Bo; Whalen, Laurel; Fahlman, Mariane

    2014-01-01

    Background: Offering physical activity clubs (PACs) for students in urban high schools can provide avenues for increased physical activity (PA); however, little is known about why some clubs are not successful. Purpose: The purpose of this qualitative study was to examine leaders' and students' perspectives on the challenges faced when…

  2. Comprehension Right from the Start: How To Organize and Manage Book Clubs for Young Readers.

    ERIC Educational Resources Information Center

    Marriott, Donna

    Noting that book clubs offer a balanced approach that respects the highly individualized nature of learning and utilizes guided reading, shared reading, listening, speaking, writing, and critical thinking skills, this book proposes how to organize and manage book clubs for young readers. The book provides suggestions on how to accomplish the…

  3. Activist Literacies: An Analysis of the Literacy Practices of a School-Based Human Rights Club

    ERIC Educational Resources Information Center

    Collin, Ross

    2012-01-01

    In this article, I examine the literacy practices of a high school-based human rights club. I investigate how the group engages in certain kinds of textual production to sponsor and arrange advisory sessions (school-wide meetings between teachers and small groups of students). More specifically, I consider how the club adapts school genres to…

  4. Authentic Science Research in Elementary School After-School Science Clubs

    ERIC Educational Resources Information Center

    Feldman, Allan; Pirog, Kelly

    2011-01-01

    In this paper we report on teachers' and students' participation in authentic science research in out of school time science clubs at elementary schools. In the program four to five teachers worked alongside practicing scientists as part of their research groups. Each teacher facilitated a club with 10-15 students who, by extension, were members…

  5. Benefits of Job Clubs for Executive Job Seekers: A Tale of Hares and Tortoises

    ERIC Educational Resources Information Center

    Kondo, Christopher T.

    2009-01-01

    This qualitative research study compares the experiences of 2 groups of executive job seekers--job club members and nonmembers--through thematic analysis of open-ended interviews. The findings indicated that job club members benefited from group learning, increased accountability, networking opportunities, emotional support, helping other members,…

  6. Pedagogy for a Few: Book Club Discussion Guides and the Modern Book Industry as Literature Teacher.

    ERIC Educational Resources Information Center

    McGinley, William; Conley, Katanna; White, John Wesley

    2000-01-01

    Examines 31 book club discussion guides prepared by major book publishers for book club readers to explore which particular ways of reading and discussing books they might sanction. Finds that they steer readers toward a rather narrow collection of academic reading practices (analytic and text-based) and away from other types of responses. (SR)

  7. The Washington Biologists' Field Club: Its Members and Its History (1900-2006)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This short paper is a review of book that outlines the 100-year history of the Washington Biologists' Field Club. The Club has had 267 members in its history from 1900-2006, several of which have been noted entomologists. Biographies (or autobiographies) are presented for each member, along with b...

  8. Attitudes of Overweight and Normal Weight Adults Regarding Exercise at a Health Club

    ERIC Educational Resources Information Center

    Miller, Wayne C.; Miller, Todd A.

    2010-01-01

    Objective: To compare attitudes of overweight (OW) and normal weight (NW) adults regarding health club exercise. Design: A 46-item survey (23 pairs of attitude/value statements) measured attitudes toward exercising at a health club 30 minutes, twice a week, for a month. Setting: Survey posted on surveymonkey.com. Respondents (men = 730, women =…

  9. Self-Capacitating Activities of Mothers' Clubs of Primarily Indigenous Membership in Bolivia.

    ERIC Educational Resources Information Center

    Felty, Amelia Smith

    A case study was conducted of the organized, cooperative efforts of women in six communities in Bolivia. From December 1978 through January 1988, visits were made to women's organizations called "mothers' clubs." Effects of club membership on members, their families, and their communities were examined. A research review showed that: (1) women can…

  10. Just Another Club? The Distinctiveness of the Relation between Religious Service Attendance and Adolescent Psychosocial Adjustment

    ERIC Educational Resources Information Center

    Good, Marie; Willoughby, Teena; Fritjers, Jan

    2009-01-01

    This study used hierarchical linear modeling to compare longitudinal patterns of adolescent religious service attendance and club attendance, and to contrast the longitudinal relations between adolescent adjustment and religious service versus club attendance. Participants included 1050 students (47% girls) encompassing a school district in…

  11. Empowering the Older Job Seeker: Experimental Evaluation of the Older Worker Job Club.

    ERIC Educational Resources Information Center

    Gray, Denis

    Because older job seekers have been shown to exhibit less job search motivation and competence than other groups, a job club program based on learning and self help principles was developed to empower the older job seeker. Of persons (N=48) who requested assistance from a local area agency on aging, half entered the job club program and half were…

  12. Community-Based English Clubs: English Practice and Social Change outside the Classroom

    ERIC Educational Resources Information Center

    Malu, Kathleen F.; Smedley, Bryce

    2016-01-01

    This article defines and provides a rationale for the creation of community-based English clubs. We offer strategies that individuals can use to create and sustain English clubs, and we suggest meeting activities that will engage members in conversations and potential community action on a range of topics such as democracy, gender equality, and…

  13. 78 FR 13086 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Job Clubs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ...; Job Clubs Study ACTION: Notice. SUMMARY: The Department of Labor (DOL), as part of its continuing... CFBNP@dol.gov . SUPPLEMENTARY INFORMATION: I. Background Over the past several decades, job search support groups, commonly referred to as ``job clubs'' have evolved into one of several...

  14. Book Clubs in Developmental Reading: Building Reading Comprehension, Fostering Reading Enjoyment, and Engaging Students

    ERIC Educational Resources Information Center

    Maldonado, Michele

    2012-01-01

    The use of book clubs in college developmental reading classes is an effective way to encourage reluctant readers to build and strengthen reading skills, foster reading enjoyment, and engage students. In addition, book clubs build a sense of community within the classroom as the students converse and share their interpretations of the reading…

  15. 76 FR 37005 - Safety Zone; Fan Pier Yacht Club Fireworks, Boston Harbor, Boston, MA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Fan Pier Yacht Club Fireworks, Boston... establishing a temporary safety zone within the Sector Boston Captain of the Port (COTP) Zone for the Fan Pier... read as follows: Sec. 165.T01-437 Safety Zone; Fan Pier Yacht Club Fireworks, Boston Harbor,...

  16. Reading Lolita in Times of War: Women's Book Clubs and the Politics of Reception

    ERIC Educational Resources Information Center

    Burwell, Catherine

    2007-01-01

    In this article I argue that women's book clubs are significant sites for learning, dialogue and the accumulation of cultural capital, and that research on North American women's book clubs should be expanded to include studies of such groups' consumption of texts by and about women living in the Middle East. Using insights from transnational…

  17. "With Our Own Wings We Fly": Native American Women Clubs, 1899-1955

    ERIC Educational Resources Information Center

    Tetzloff, Lisa M.

    2007-01-01

    This article traces the history of Native American women clubs from 1899-1955. In its heyday in the early 1900s, the women's club movement attracted about two million participants nationwide. Excluded from higher education at the time, women were moved to create their own opportunities to learn, meeting regularly in small groups to study such…

  18. Self-Esteem Profile among the Female Futsal-Football Players at Jordanian Clubs

    ERIC Educational Resources Information Center

    Khasawneh, Aman

    2015-01-01

    This study aimed at identifying the level of physical and body self-esteem among the female futsal - football players at Jordanian clubs. The sample of the study was composed of (38) female players among the Jordanian clubs' players of futsal-football who were chosen randomly out of the study community, and the self-esteem scale was used,…

  19. Private Satisfactions and Public Disorders: "Fight Club," Patriarchy, and the Politics of Masculine Violence.

    ERIC Educational Resources Information Center

    Giroux, Henry A.

    2001-01-01

    Analyzes the narrative structure of the film "Fight Club," addressing its critique of consumerism and its celebration of masculinity. Addresses the representational politics that structure the movie, especially its deeply conventional views of violence, gender relations, and masculinity. Considers the role that "Fight Club" and other cultural…

  20. Conflict in a Sixth-Grade Book Club: The Impact of a Rule-Driven Discourse

    ERIC Educational Resources Information Center

    Hill, K. Dara

    2008-01-01

    This study examines unintended consequences during a 6th-grade book club discussion of Bette Bao Lord's (1984) In the Year of the Boar and Jackie Robinson. The participants modeled a book club discussion, otherwise known as the fish bowl, for a newly enrolled student. Unintended consequences occurred within the realm of deviating from the rules of…

  1. Prominence and control: the weighted rich-club effect.

    PubMed

    Opsahl, Tore; Colizza, Vittoria; Panzarasa, Pietro; Ramasco, José J

    2008-10-17

    Complex systems are often characterized by large-scale hierarchical organizations. Whether the prominent elements, at the top of the hierarchy, share and control resources or avoid one another lies at the heart of a system's global organization and functioning. Inspired by network perspectives, we propose a new general framework for studying the tendency of prominent elements to form clubs with exclusive control over the majority of a system's resources. We explore associations between prominence and control in the fields of transportation, scientific collaboration, and online communication.

  2. Atrial Septal Aneurysm Presenting as Clubbing without Clinically Apparent Cyanosis.

    PubMed

    Goyal, Laxmi Kant; Banerjee, S; Yadav, R N; Singh, Gajraj; Ganguli, Sujata; Isran, Rohit

    2015-09-01

    Atrial septal aneurysm (ASA) is a localised "saccular" deformity which protrudes to the right or the left atrium or on both sides. It is a rare, but well recognised cardiac abnormality. It is usually an incidental finding or may presents as atrial arrhythmias or arterial embolism. Though it is an acyanotic congenital heart disease but it may result in significant right to left shunt and cyanosis. We describe a patient of ASA with atrial septal defect who presented with clubbing and right to left shunt without clinically apparent cyanosis. PMID:27608873

  3. The Juneau County Inventors & Entrepreneurs Club Experience: Catch the Culture! Rural Research Report. Volume 21, Issue 4, Fall 2010

    ERIC Educational Resources Information Center

    Whipple, Terry

    2010-01-01

    Working from the premise that innovation and entrepreneurship will thrive if cultivated in a supportive environment, the Juneau County Economic Development Corporation (JCEDC) introduced a "club concept" as a key component of its strategic plan. The Wisconsin-based development corporation created the Inventors & Entrepreneurs Club (I&E Club) to…

  4. "Talk What Others Think You Can't Talk": HIV/AIDS Clubs as Peer Education in Ugandan Schools

    ERIC Educational Resources Information Center

    Norton, Bonny; Mutonyi, Harriet

    2007-01-01

    In this article, we make the case that HIV/AIDS clubs in Ugandan schools provide valuable information to students who may not have easy access to health services. As one club motto suggests, the clubs "talk what others think you can't talk". The innovative peer education methods, which include drama, popular culture and community outreach all have…

  5. Modification of Triclosan Scaffold in Search of Improved Inhibitors for Enoyl-Acyl Carrier Protein (ACP) Reductase in Toxoplasma gondii

    PubMed Central

    Stec, Jozef; Fomovska, Alina; Afanador, Gustavo A.; Muench, Stephen P.; Zhou, Ying; Lai, Bo-Shiun; Bissati, Kamal El; Hickman, Mark R.; Lee, Patty J.; Leed, Susan E.; Auschwitz, Jennifer M.; Sommervile, Caroline; Woods, Stuart; Roberts, Craig W.; Rice, David; Prigge, Sean T.; McLeod, Rima; Kozikowski, Alan P.

    2013-01-01

    Through our focused effort to discover new and effective agents against toxoplasmosis, a structure-based drug design approach was utilized to develop a series of potent inhibitors of the enoyl-acyl carrier protein (ACP) reductase (ENR) enzyme in Toxoplasma gondii (TgENR). Modifications to positions 5 and 4′ of the well-known ENR inhibitor triclosan afforded a series of 29 new analogs. Among the resulting compounds, many showed high potency and improved physicochemical properties in comparison with the lead. The most potent compounds 16a and 16c have IC50 values of 250 nM against Toxoplasma gondii tachyzoites without apparent toxicity to the host cells. Their IC50 values against the recombinant TgENR were 43 and 26 nM, respectively. Additionally, 11 other analogs in this series had IC50 values ranging from 17 to 130 nM in the enzyme-based assay. With respect to their excellent in vitro activity as well as improved drug-like properties, the lead compounds 16a and 16c are deemed to be an excellent starting point for the development of new medicines to effectively treat Toxoplasma gondii infections. PMID:23776166

  6. A [32P]-NAD+-based method to identify and quantitate long residence time enoyl-ACP reductase inhibitors

    PubMed Central

    Yu, Weixuan; Neckles, Carla; Chang, Andrew; Bommineni, Gopal Reddy; Spagnuolo, Lauren; Zhang, Zhuo; Liu, Nina; Lai, Christina; Truglio, James; Tonge, Peter J.

    2015-01-01

    The classical methods for quantifying drug-target residence time (tR) use loss or regain of enzyme activity in progress curve kinetic assays. However, such methods become imprecise at very long residence times, mitigating the use of alternative strategies. Using the NAD(P)H-dependent FabI enoyl-ACP reductase as a model system, we developed a Penefsky column-based method for direct measurement of tR, where the off-rate of the drug was determined with radiolabeled [adenylate-32P] NAD(P+) cofactor. Twenty-three FabI inhibitors were analyzed and a mathematical model was used to estimate limits to the tR values of each inhibitor based on percent drug-target complex recovery following gel filtration. In general, this method showed good agreement with the classical steady state kinetic methods for compounds with tR values of 10-100 min. In addition, we were able to identify seven long tR inhibitors (100-1500 min) and to accurately determine their tR values. The method was then used to measure tR as a function of temperature, an analysis not previously possible using the standard kinetic approach due to decreased NAD(P)H stability at elevated temperatures. In general, a 4-fold difference in tR was observed when the temperature was increased from 25 °C to 37 °C . PMID:25684450

  7. 3-Oxoacyl-ACP Reductase from Schistosoma japonicum: Integrated In Silico-In Vitro Strategy for Discovering Antischistosomal Lead Compounds

    PubMed Central

    Liu, Jian; Dyer, Dave; Wang, Jipeng; Wang, Shuqi; Du, Xiaofeng; Xu, Bin; Zhang, Haobing; Wang, Xiaoning; Hu, Wei

    2013-01-01

    Background Schistosomiasis is a disease caused by parasitic worms and more than 200 million people are infected worldwide. The emergence of resistance to the most commonly used drug, praziquantel (PZQ), makes the development of novel drugs an urgent task. 3-oxoacyl-ACP reductase (OAR), a key enzyme involved in the fatty acid synthesis pathway, has been identified as a potential drug target against many pathogenic organisms. However, no research on Schistosoma japonicum OAR (SjOAR) has been reported. The characterization of the SjOAR protein will provide new strategies for screening antischistosomal drugs that target SjOAR. Methodology/Principal Findings After cloning the SjOAR gene, recombinant SjOAR protein was purified and assayed for enzymatic activity. The tertiary structure of SjOAR was obtained by homology modeling and 27 inhibitor candidates were identified from 14,400 compounds through molecular docking based on the structure. All of these compounds were confirmed to be able to bind to the SjOAR protein by BIAcore analysis. Two compounds exhibited strong antischistosomal activity and inhibitory effects on the enzymatic activity of SjOAR. In contrast, these two compounds showed relatively low toxicity towards host cells. Conclusions/Significance The work presented here shows the feasibility of isolation of new antischistosomal compounds using a combination of virtual screening and experimental validation. Based on this strategy, we successfully identified 2 compounds that target SjOAR with strong antischistosomal activity but relatively low cytotoxicity to host cells. PMID:23762275

  8. Making sporting clubs healthy and welcoming environments: a strategy to increase participation.

    PubMed

    Eime, Rochelle M; Payne, Warren R; Harvey, Jack T

    2008-04-01

    Sporting clubs are an ideal setting to promote community-wide participation in physical activity. Using the principles of the Ottawa Charter as a guide, this study explored the factors affecting the development of supportive environments as a mechanism to increase participation in club sport. The Victorian Health Promotion Foundation (VicHealth) funds State Sporting Associations (SSAs) to develop healthy and welcoming environments (HWE) in their associated clubs. The program focus areas are: welcoming and inclusive environments, sports injury prevention, 'smoke-free' environments, responsible serving of alcohol, sun protection and healthy eating. This paper sought to determine whether or not SSA Executive Officers (EOs) believe that the creation of a supportive environment will facilitate sporting club membership and to identify the factors that affect the development of the HWEs. Forty-two (82.4%) of the 51 funded SSAs completed a general survey and 36 (70.6%) of EOs responded to questions that were specifically addressed to them. EOs from six SSAs also participated in semi-structured interviews. SSA EOs (97.2%) believed that the creation of HWE in clubs would facilitate increases in participant membership. However, the data indicate incomplete development of the HWE focus areas at the club level because of limited club capacity and limited SSA support. Reportedly, the SSAs are at the stage of raising program awareness at the club level. It is suggested that SSAs should plan a structured approach to the development of HWEs that acknowledges the diverse capacity of their clubs, and garner the support of key club volunteers in order to establish HWEs.

  9. Journalism Program to Fill Gap

    ERIC Educational Resources Information Center

    Goodman, Henry

    1970-01-01

    The preparation of interested and well-trained individuals for service in editorial, advertising, and management positions on rural and small town newspapers is the intent of Sampson Technical Institute's 2-year pilot journalism program. (JO)

  10. Sex in Drosophila mauritiana: a very high level of amino acid polymorphism in a male reproductive protein gene, Acp26Aa.

    PubMed

    Tsaur, S C; Ting, C T; Wu, C I

    2001-01-01

    Many genes pertaining to male reproductive functions have been shown to evolve rapidly between species, and evidence increasingly suggest the influence of positive Darwinian selection. The accessory gland protein gene (Acp26Aa) of Drosophila is one such example. In order to understand the mechanism of selection, it is often helpful to examine the pattern of polymorphism. We report here that the level of amino acid polymorphism in the N-terminal quarter of Acp26Aa is high in Drosophila melanogaster and is unprecedented in its sibling species Drosophila mauritiana. We postulate that (1) this N-terminal segment may play a role in sperm competition, and (2) D. mauritiana may have been under much more intense sexual selection than other species. Both postulates have important ramifications and deserve to be tested rigorously.

  11. EDITORIAL: Changes to the journal Changes to the journal

    NASA Astrophysics Data System (ADS)

    Zheludev, Nikolay I.

    2010-01-01

    It is a privilege to be Editor-in-Chief of Journal of Optics at this exciting time when the use of light spearheads the development of new technologies in telecommunications, green energy, manufacturing, medicine and defence, just to mention a few. These technological advances, seen by many as the next photonic technological revolution, are underpinned by fundamental and applied research in the following key directions: Nanophotonics and plasmonics Metamaterials and structured photonic materials Nonlinear and ultrafast optics Photonics at the life science interface Information and communication optics Integrated optics systems and devices Material processing with light Propagation, diffraction and scattering This is where Journal of Optics focuses its attention. This editorial marks the first issue of the journal published under the abbreviated name (shortened from Journal of Optics A: Pure and Applied Optics). The name change is just one of a series of changes introduced in the last year, along with the 8 subject sections listed above and the appointment of Section Editors. With the name change, we will also update the look of the journal by introducing colour cover images which will feature some of the most exciting research in the journal. We have retained many of the journal's original selling points: we are found in thousands of libraries around the world, and will continue our policy of free web access to all papers for 30 days after publication, ensuring broad and unrestricted dissemination of your research results. We will also continue our strong and well respected special issue and topical review programmes and we are always grateful to receive new suggestions for special issues or review articles. Along with the Editorial Board, I would like to thank the authors, referees and readers who have contributed to the success of Journal of Optics. The increasing quality and visibility of the journal, as demonstrated by the dramatic increase in its impact factor

  12. Baseline Testing of the Club Car Carryall With Asymmetric Ultracapacitors

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2003-01-01

    The NASA John H. Glenn Research Center initiated baseline testing of the Club Car Carryall with asymmetric ultracapacitors as a way to reduce pollution in industrial settings, reduce fossil fuel consumption, and reduce operating costs for transportation systems. The Club Car Carryall provides an inexpensive approach to advance the state of the art in electric vehicle technology in a practical application. The project transfers space technology to terrestrial use via non-traditional partners, and provides power system data valuable for future space applications. The work was done under the Hybrid Power Management (HPM) Program, which includes the Hybrid Electric Transit Bus (HETB). The Carryall is a state of the art, ground up, electric utility vehicle. A unique aspect of the project was the use of a state of the art, long life ultracapacitor energy storage system. Innovative features, such as regenerative braking through ultracapacitor energy storage, are planned. Regenerative braking recovers much of the kinetic energy of the vehicle during deceleration. The Carryall was tested with the standard lead acid battery energy storage system, as well as with an asymmetric ultracapacitor energy storage system. The report concludes that the Carryall provides excellent performance, and that the implementation of asymmetric ultracapacitors in the power system can provide significant performance improvements.

  13. Participation in a Video Club: Influences on Teachers and Teaching

    NASA Astrophysics Data System (ADS)

    Barnhart, Tara

    This dissertation examines the development of critical colleagueship among five secondary science teachers in a semester-long video club. The design of the video club was intended to promote a focus on student thinking and experimentation with elements of ambitious science teaching. Over time, participants sustained a focus on interpreting students' disciplinary thinking using evidence and began to problematize aspects of instruction related to making student thinking visible. Some participants attempted to change instruction to gain greater access to students' disciplinary thinking while others did not. Efforts to experiment with instructional practice appeared related to alignment between participants' learning goals and curricular contexts and the goals of the professional development design. Features such as framing activities, types of artifacts used, and facilitation, interacted differently over time to influence participant learning. Analysis revealed various tensions among the elements of the learning ecology that influenced participation. Findings from this study contribute to what is known about the importance of skilled facilitation as part of a learning ecology (Cobb, Confrey, diSessa, Lehrer, & Schauble, 2003) and has implications for the design of site-based professional development with secondary teachers.

  14. Cryopreservation of collared peccaries (Tayassu tajacu) semen using a powdered coconut water (ACP-116c) based extender plus various concentrations of egg yolk and glycerol.

    PubMed

    Silva, M A; Peixoto, G C X; Lima, G L; Bezerra, J A B; Campos, L B; Paiva, A L C; Paula, V V; Silva, A R

    2012-08-01

    The objective was to determine the effectiveness of a powdered coconut water-based extender (ACP-116c), plus various concentrations of egg-yolk and glycerol, as an alternative for cryopreservation of collared peccary semen. Twelve ejaculates were obtained from captive adult males by electroejaculation, and evaluated for sperm motility, kinetic rating, viability, morphology, and functional membrane integrity. The ejaculates were apportioned into aliquots that were diluted in Tris plus 10% egg yolk and 3% glycerol, or in ACP-116c plus 10 or 20% egg yolk and 1.5 or 3% glycerol. Samples were frozen in liquid nitrogen and, after 1 mo, thawed at 37 °C for 1 min. After thawing, samples were evaluated as reported for fresh semen, and also for sperm membrane integrity (fluorescent probes) and kinematic parameters (computerized analysis). Results were presented as means ± SEM. Freezing and thawing decreased sperm characteristics relative to fresh semen. Overall, ACP-116c plus 20% egg yolk and 3% glycerol provided better (P < 0.05) sperm motility and kinetic rating (48 ± 6.1% and 2.8 ± 0.2, respectively) after thawing than Tris extender (30.4 ± 5.7% and 2.4 ± 0.2). However, there were no differences (P > 0.05) among treatments with regard to the other sperm characteristics. Based on computerized motion analysis, total (26.5 ± 5.9%) and progressive (8.1 ± 2.2%) motility were best preserved (P < 0.05) with the above-mentioned treatment. In conclusion, a coconut water-based extender, ACP-116c, plus 20% egg yolk and 3% glycerol, was effective for cryopreservation of semen from collared peccaries.

  15. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase

    DOE PAGES

    Wang, Hui; Liu, Li; Lu, Yang; Pan, Pan; Hooker, Jacob M.; Fowler, Joanna S.; Tonge, Peter J.

    2015-07-14

    PT70 is a diaryl ether inhibitor of InhA, the enoyl-ACP reductase in the Mycobacterium tuberculosis fatty acid biosynthesis pathway. It has a residence time of 24 min on the target, and also shows antibacterial activity in a mouse model of tuberculosis infection. Due to the interest in studying target tissue pharmacokinetics of PT70, we developed a method to radiolabel PT70 with carbon-11 and have studied its pharmacokinetics in mice and baboons using positron emission tomography.

  16. An Overview and Analysis of Journal Operations, Journal Publication Patterns, and Journal Impact in School Psychology and Related Fields

    ERIC Educational Resources Information Center

    Floyd, Randy G.; Cooley, Kathryn M.; Arnett, James E.; Fagan, Thomas K.; Mercer, Sterett H.; Hingle, Christine

    2011-01-01

    This article describes the results of three studies designed to understand better the journal operations, publishing practices, and impact of school psychology journals in recent years. The first study presents the results of a survey focusing on journal operations and peer-review practices that was completed by 61 journal editors of school…

  17. Class Room Seminar and Journal Club (CRSJC) as an Effective Teaching Learning Tool: Perception to Post Graduation Pharmacy Students

    ERIC Educational Resources Information Center

    Dahiya, Sunita; Dahiya, Rajiv

    2015-01-01

    Theory and practicals are two essential components of pharmacy course curriculum; but in addition to appearing and passing examination with good score grades, pharmacy post graduation (PG) pursuing students are essentially required to develop some professional skills which might not be attained solely by conventional class room programs. This…

  18. Peer Feedback Enhances a "Journal Club" for Undergraduate Science Students That Develops Oral Communication and Critical Evaluation Skills

    ERIC Educational Resources Information Center

    Colthorpe, Kay; Chen, Xuebin; Zimbardi, Kirsten

    2014-01-01

    Effective science communication is one of the key skills undergraduates must achieve and is one of the threshold learning outcomes for Science (TLO 4.1). In addition, presenting published research to their peers allows students to critically evaluate scientific research (TLO 3.1) and develop a deeper appreciation for the link between experimental…

  19. The "Crane Problem" in Journalism Historiography.

    ERIC Educational Resources Information Center

    Marmarelli, Ron

    Attempting to correct and amplify the portrayal of Stephen Crane in journalism history, this paper provides an analysis of relevant works in journalism and other disciplines in order to point out the weaknesses in the journalism historiography and to show how they apparently came about. Evidence is presented from the literature of journalism,…

  20. Creativity and Mathematics: Using Learning Journals

    ERIC Educational Resources Information Center

    Coles, Alf; Banfield, Gemma

    2012-01-01

    Does the term "learning journal" readily conjure up an image of something that is part of the normal mathematics classroom? Personally, do you ever use a journal of some form to help you organise your thoughts? Or, put quite simply--what is a learning journal? It might be that you are unfamiliar with the label, but journals are one type of…