Science.gov

Sample records for acp journal club

  1. Redesigning journal club in residency.

    PubMed

    Al Achkar, Morhaf

    2016-01-01

    The gap between production and implementation of knowledge is the main reason for the suboptimal quality of health care. To eliminate this gap and improve the quality of patient care, journal club (JC) in graduate medical education provides an opportunity for learning the skills of evidence-based medicine. JC, however, continues to face many challenges mainly due to poorly defined goals, inadequate preparation, and lack of interest. This article presents an innovative model to prepare and present JC based on three pillars: dialogical learning through group discussion, mentored residents as peer teachers, and including JC as part of a structured curriculum to learn evidence-based medicine. This engaging model has the potential to transform JC from a moribund session that is daunting for residents into a lively discussion to redefine clinical practice using the most current evidence. PMID:27313486

  2. Redesigning journal club in residency

    PubMed Central

    Al Achkar, Morhaf

    2016-01-01

    The gap between production and implementation of knowledge is the main reason for the suboptimal quality of health care. To eliminate this gap and improve the quality of patient care, journal club (JC) in graduate medical education provides an opportunity for learning the skills of evidence-based medicine. JC, however, continues to face many challenges mainly due to poorly defined goals, inadequate preparation, and lack of interest. This article presents an innovative model to prepare and present JC based on three pillars: dialogical learning through group discussion, mentored residents as peer teachers, and including JC as part of a structured curriculum to learn evidence-based medicine. This engaging model has the potential to transform JC from a moribund session that is daunting for residents into a lively discussion to redefine clinical practice using the most current evidence. PMID:27313486

  3. New Methods for an Undergraduate Journal Club

    ERIC Educational Resources Information Center

    Clark, Jordan M.; Rollins, Adam W.; Smith, Philip

    2014-01-01

    Journal clubs have been used to advance students' scientific skills beyond basic knowledge and comprehension, but students often view the traditional format of analyzing reported data and experimental design as laborious and intimidating. As such, the traditional approach can diminish student engagement and enthusiasm for the value of…

  4. Implementing a successful journal club in an anesthesiology residency program.

    PubMed

    Pitner, Nathaniel D; Fox, Chris A; Riess, Matthias L

    2013-01-01

    Journal clubs are an integral element of residency training. We report the successful implementation of a monthly structured journal club in our anesthesia residency program. Based on resident surveys before and one year after its start, the journal club led to a significantly higher confidence in how to critically appraise literature and present a manuscript. The journal club also improved the residents' ability to search the literature and their statistical knowledge, skills that are essential in the practice of evidence-based medicine. We describe key features that may aid other training programs in organizing a stimulating an educational and sustainable journal club. PMID:24358844

  5. The Prevalence and Practices of Academic Library Journal Clubs

    ERIC Educational Resources Information Center

    Young, Philip; Vilelle, Luke

    2011-01-01

    Increased mention of journal clubs in the library literature and the recent creation of clubs at the authors' institutions sparked curiosity about how widespread they are in academic libraries. An online survey announced on library listservs assessed their prevalence and practices. Library journal clubs promote current awareness, analysis skills,…

  6. Journal clubs. Prevalence, format, and efficacy in PM&R.

    PubMed

    Moberg-Wolff, E A; Kosasih, J B

    1995-01-01

    Journal clubs can play an integral part in graduate medical education. They promote critical thinking, dissemination of information, and research and impact clinical practice. Little has been written, however, about how to organize a journal club or improve its efficacy. Although numerous articles discuss how journal clubs can be used to evaluate medical literature, only a few have examined what physicians are actually doing. We surveyed all accredited PM&R program chief/residents to ascertain the prevalence, format, and efficacy of PM&R residency journal clubs. All programs that responded (89%) reported having a journal club, with most stating its purpose was to disseminate information from the current literature. Review of classic articles and specialty topics (e.g., electromyography, sports medicine) was fairly uncommon. Eighty-four percent of journal clubs were department-sponsored, and most met monthly for 1 hr during the workday. Typically, four or more articles were presented under the guidance of the chief or other resident. Impacting clinical practice and teaching critical analysis were other important goals of the journal clubs, yet most (76%) lacked an organized method for critical review. This, in addition to poor faculty attendance, was a chief concern of those surveyed. Surprisingly, journal club participation was not felt to significantly alter the amount of reading residents did. Although most felt their journal clubs were successful, improving faculty participation, strengthening critical analysis skills, identifying and incorporating classic articles, improving clinical relevance, and providing a mechanism for feedback may further improve journal club efficacy and participant satisfaction. PMID:7779334

  7. Beyond content: leadership development through a journal club.

    PubMed

    Kattan, Jessica A; Apostolou, Andria; Al-Samarrai, Teeb; El Bcheraoui, Charbel; Kay, Meagan K; Khaokham, Christina B; Pillai, Parvathy; Sapkota, Sanjeeb; Jani, Asim A; Koo, Denise; Taylor, William C

    2014-11-01

    CDC designed its Health Systems Integration Program to prepare leaders to function at the interface of public health and health care. Specific Health Systems Integration Program competencies in the areas of communication, analysis and assessment, and health systems were developed to nurture evidence-based decision-making and leadership skills crucial for future public health leaders. The program therefore designed an innovative journal club as part of its competency-based curriculum not only to meet the standard goals for a journal club-critical reading, interpretation, and acquiring content knowledge-but also to foster leadership development. This report describes the Health Systems Integration Program journal club format, its implementation, challenges, and key elements of success. Other programs using a journal club model as a learning format might consider using the Health Systems Integration Program's innovative approach that focuses on leadership development. PMID:25439249

  8. Journal club: screen, select, probe & evaluate.

    PubMed

    Kanthraj, G R; Srinivas, C R

    2005-01-01

    Postgraduate dermatology training programs like seminars, panel discussions, and case presentations help residents to acquire knowledge. Journal club (JC) exercises help residents to update themselves with the current literature. What article a resident should choose and how a resident should evaluate and analyze an article or critically appraise a topic are issues that are most relevant for the success of a JC. Little guidance is available in the biomedical literature on how to deal with such issues. The objective of this article is to provide guidance to neophytes on dealing with JC exercises in a way that helps them in learning the critical appraisal skills. A review of the literature and of the author's experience in JC exercises will be presented. Knowing the methodology of rapid screening of articles along with the art of evaluating them, coupled with a sound knowledge of epidemiology and bio-statistics, helps a resident to select appropriate articles and discard poorly conceived or designed topics that may not generate interest in JC attendees. Hence, such an approach helps the resident in acquiring new knowledge in the shortest time. Choosing the right topic and then applying the newly obtained information to clinical practice, participants succeed in making the JC a valuable learning experience. Further, such well-formatted JCs help residents to improve the quality of health care delivered to patients. PMID:16394494

  9. Journal clubs: a strategy to teach civility to nursing students.

    PubMed

    Kerber, Cindy; Jenkins, Sheryl; Woith, Wendy; Kim, Myoungjin

    2012-05-01

    Incivility affects nurses and nursing students and can negatively influence patient care and the quality of nursing education. The Institute of Medicine, The Joint Commission, and the American Association of Colleges of Nursing recommended implementation of strategies to manage incivility and build social capital. The purpose of this mixed methods study was to explore the influence of a journal club as an educational intervention to build civility and academic integrity among nursing students. Seventy-nine nursing students completed the Nurses' Intervention for Civility Education Questionnaire and the Ways of Coping Questionnaire before and after the Civility Journal Club intervention. Students involved in the Civility Journal Club were more aware of civility and incivility, more likely to be helpful to their peers, and better equipped to cope with episodes of incivility. PMID:22432534

  10. Social media, medicine and the modern journal club.

    PubMed

    Topf, Joel M; Hiremath, Swapnil

    2015-04-01

    Medical media is changing along with the rest of the media landscape. One of the more interesting ways that medical media is evolving is the increased role of social media in medical media's creation, curation and distribution. Twitter, a microblogging site, has become a central hub for finding, vetting, and spreading this content among doctors. We have created a Twitter journal club for nephrology that primarily provides post-publication peer review of high impact nephrology articles, but additionally helps Twitter users build a network of engaged people with interests in academic nephrology. By following participants in the nephrology journal club, users are able to stock their personal learning network. In this essay we discuss the history of medical media, the role of Twitter in the current states of media and summarize our initial experience with a Twitter journal club. PMID:25906989

  11. The Use of Journal Clubs in Science Teacher Education

    NASA Astrophysics Data System (ADS)

    Tallman, Karen A.; Feldman, Allan

    2016-03-01

    This qualitative study explored how in a 7-month-long journal club pre- and inservice science teachers engaged with education research literature relevant to their practice to reduce the theory-practice gap. In the journal club they had the opportunity to critique and analyze peer-reviewed science education articles in the context of their classroom practice. Data sources included audio recordings of the meetings; semi-structured pre- and post-interviews of the teachers; focus groups; and artifacts (e.g., journal articles, reflective paper, email exchanges, and researcher's field notes). Data were analyzed using the techniques of grounded theory (Corbin & Strauss in Basics of qualitative research, 3rd ed. Sage, Thousand Oaks, 2008). In addition we used some preconceived categories that we created from existing literature on journal clubs and communities of practice (Newswander & Borrego in European Journal of Engineering Education 34(6): 561-571, 2009; Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) and from our previous research (Tallman & Feldman, 2012). We found that the journal club incorporated the three characteristics of a community of practice (Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) into its functioning (mutual engagement, joint enterprise, and shared repertoire). The teachers mutually engaged around the joint enterprise of reading, critiquing, and understanding the research studies with the goal of improving practice. The teachers also asked each other analytical questions, which became a shared repertoire of the journal club. They reflected on their practice by presenting, reading, and discussing the articles, which helped them to determine whether and how the findings from the articles could be incorporated into their teaching practice. In doing so, they learned the skills needed to critique the research literature in

  12. The Use of Journal Clubs in Science Teacher Education

    NASA Astrophysics Data System (ADS)

    Tallman, Karen A.; Feldman, Allan

    2016-04-01

    This qualitative study explored how in a 7-month-long journal club pre- and inservice science teachers engaged with education research literature relevant to their practice to reduce the theory-practice gap. In the journal club they had the opportunity to critique and analyze peer-reviewed science education articles in the context of their classroom practice. Data sources included audio recordings of the meetings; semi-structured pre- and post-interviews of the teachers; focus groups; and artifacts (e.g., journal articles, reflective paper, email exchanges, and researcher's field notes). Data were analyzed using the techniques of grounded theory (Corbin & Strauss in Basics of qualitative research, 3rd ed. Sage, Thousand Oaks, 2008). In addition we used some preconceived categories that we created from existing literature on journal clubs and communities of practice (Newswander & Borrego in European Journal of Engineering Education 34(6): 561-571, 2009; Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) and from our previous research (Tallman & Feldman, 2012). We found that the journal club incorporated the three characteristics of a community of practice (Wenger in Communities of practice: learning, meaning, and identity. Cambridge University Press, Cambridge, 1998) into its functioning (mutual engagement, joint enterprise, and shared repertoire). The teachers mutually engaged around the joint enterprise of reading, critiquing, and understanding the research studies with the goal of improving practice. The teachers also asked each other analytical questions, which became a shared repertoire of the journal club. They reflected on their practice by presenting, reading, and discussing the articles, which helped them to determine whether and how the findings from the articles could be incorporated into their teaching practice. In doing so, they learned the skills needed to critique the research literature in

  13. Teaching Note--Incorporating Journal Clubs into Social Work Education: An Exploratory Model

    ERIC Educational Resources Information Center

    Moore, Megan; Fawley-King, Kya; Stone, Susan I.; Accomazzo, Sarah M.

    2013-01-01

    This article outlines the implementation of a journal club for master's and doctoral social work students interested in mental health practice. It defines educational journal clubs and discusses the history of journal clubs in medical education and the applicability of the model to social work education. The feasibility of implementing…

  14. Biology Blogs: An Online Journal Club & Assessment Tool

    ERIC Educational Resources Information Center

    De Souza-Hart, Janet A.

    2010-01-01

    A "blog" can be used as an online journal club to supplement classroom learning. When crafted in a certain way, it can help students develop their scientific reading comprehension, critical thinking, and writing skills in a way that can easily be assessed by educators.

  15. Interdisciplinary Journal Club: Advancing Knowledge Translation in a Rural State

    ERIC Educational Resources Information Center

    Dennis, Ruth E.; Potvin, Marie-Christine; MacLeod, Marie

    2010-01-01

    Professionals who provide health and related supports and services to children with disabilities in educational programs and community settings must practice in an evidence-based manner to ensure children and families receive the highest quality care. Vermont's Interdisciplinary Journal Club provides a successful approach to supporting…

  16. Journal Club Format Emphasizing Techniques of Critical Reading.

    ERIC Educational Resources Information Center

    Woods, James R., Jr.; Winkel, Craig E.

    1982-01-01

    The journal club format offers the resident a unique opportunity to develop specific skills in reading, comprehending, and evaluating medical literature. A course designed for residents in obstetrics and gynecology at the Letterman Army Medical Center and at the University of Cincinnati is described. (MLW)

  17. An Undergraduate Journal Club Experience: A Lesson in Critical Thinking

    ERIC Educational Resources Information Center

    Roberts, Jennifer

    2009-01-01

    In an effort to better prepare undergraduate students to read and critically evaluate scientific literature, a journal club experience was introduced into a university's bachelor of science curriculum. As a result of this experience, students have been found to be more thoughtful, poised, and articulate presenters, a fact that they, the students,…

  18. Chinese Obstetrics & Gynecology journal club: a randomised controlled trial

    PubMed Central

    Tsui, Ilene K; Dodson, William C; Kunselman, Allen R; Kuang, Hongying; Han, Feng-Juan; Legro, Richard S; Wu, Xiao-Ke

    2016-01-01

    Objectives To assess whether a journal club model could improve comprehension and written and spoken medical English in a population of Chinese medical professionals. Setting and participants The study population consisted of 52 medical professionals who were residents or postgraduate master or PhD students in the Department of Obstetrics and Gynecology, Heilongjiang University of Chinese Medicine, China. Intervention After a three-part baseline examination to assess medical English comprehension, participants were randomised to either (1) an intensive journal club treatment arm or (2) a self-study group. At the conclusion of the 8-week intervention participants (n=52) were re-tested with new questions. Outcome measures The primary outcome was the change in score on a multiple choice examination. Secondary outcomes included change in scores on written and oral examinations which were modelled on the Test of English as a Foreign Language (TOEFL). Results Both groups had improved scores on the multiple choice examination without a statistically significant difference between them (90% power). However, there was a statistically significant difference between the groups in mean improvement in scores for both written (95% CI 1.1 to 5.0; p=0.003) and spoken English (95% CI 0.06 to 3.7; p=0.04) favouring the journal club intervention. Conclusions Interacting with colleagues and an English-speaking facilitator in a journal club improved both written and spoken medical English in Chinese medical professionals. Journal clubs may be suitable for use as a self-sustainable teaching model to improve fluency in medical English in foreign medical professionals. Trial registration number NCT01844609. PMID:26823180

  19. Global emergency medicine journal club: social media responses to the January 2014 online emergency medicine journal club on subarachnoid hemorrhage.

    PubMed

    Chan, Teresa M; Rosenberg, Hans; Lin, Michelle

    2014-07-01

    From January 20 to 24, 2014, Annals continued a successful collaboration with an academic Web site, Academic Life in Emergency Medicine (ALiEM), to host another Global Emergency Medicine Journal Club session featuring the 2013 Journal of the American Medical Association article "Clinical Decision Rules to Rule Out Subarachnoid Hemorrhage for Acute Headache" by Perry et al. This online journal club used the power of rapid Twitter conversations, a live videocast with the authors, and more detailed discussions hosted on the ALiEM Web site's comment section. There were more than 1,431 individuals from 501 cities in 59 countries who viewed the blog post. During this 5-day event, 28 comments (average word count 153 words) and 206 tweets were made. This summary article details the community discussion, shared insights, and analytic data generated during this novel, multiplatform approach. PMID:24951414

  20. ASBMB Journal Club - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    On Wednesday, November 12, 2014 from 2:00 PM to 3:00 PM EST, Daniel Liebler, PhD (Vanderbilt University) and Karin Rodland, PhD (Pacific Northwestern National Laboratory) and Ruedi Aebersold, PhD (Swiss Federal Institute of Technology) will share their research insight as part of the ASBMB Journal Club.  Both Doctors Liebler and Rodland are Principal Investigators in the NCI’s Clinical Proteomic Tumor Analysis Consortium.

  1. [An interdisciplinary journal club improves hospital staff competence and commitment].

    PubMed

    Qvist, Ina; Østergaard, Mie; Aarhus, Rikke; Mikkelsen, Lone Ramer; Jørgensen, Lene Bastrup

    2015-02-01

    The demands of the health-care sector for quality and evidence-based knowledge require nurses, secretaries and allied health-care professionals to keep up to date professionally. An interdisciplinary journal club (IJC) provides a self-reported improvement in the competence of critical reading as well as increasing knowledge about research designs and research methods. Furthermore, IJC leads to an increased sense of community, understanding of an interdisciplinary culture and appears to strengthen the foundations for cooperation across disciplines. PMID:25650578

  2. Undergraduate Journal Club as an Intervention to Improve Student Development in Applying the Scientific Process

    ERIC Educational Resources Information Center

    Sandefur, Conner I.; Gordy, Claire

    2016-01-01

    We developed and implemented a series of workshops and seminars in an undergraduate journal club targeted at improving student development in applying the scientific process. Students were surveyed before and after participating in the club about their confidence in accessing, analyzing, and reporting scientific research. Post-club, the students…

  3. Undergraduate journal club as an intervention to improve student development in applying the scientific process

    PubMed Central

    Sandefur, Conner I; Gordy, Claire

    2016-01-01

    Active learning improves student performance in STEM courses. Exposure to active learning environments generally occurs through traditional laboratory courses and independent research, both of which require access to resources that are limited at many universities. A previously reported active learning-based undergraduate journal club improved student achievement in communicating science. Here, we expanded on this previous journal club to improve student performance in the process of science. We developed and implemented a series of workshops and seminars referred to as “CASL Club,” an undergraduate journal club targeted at improving student development in applying the scientific process. Students were surveyed before and after CASL club about their confidence in accessing, analyzing, and reporting scientific research. Post-CASL club, the students reported increases in confidence in their abilities to access and present scientific articles and write scientific abstracts. Additionally, the students reported improved confidence and performance in their courses. Compared to the previous journal club study, the majority of sampled journal club participants were not exposed to primary literature as part of their general coursework. Our results illustrate active-learning based undergraduate journal clubs as a way to expose students to primary literature and improve students’ ability to apply scientific process in an active-learning environment at resource-limited universities. PMID:27212737

  4. Globalization of Continuing Professional Development by Journal Clubs via Microblogging: A Systematic Review

    PubMed Central

    Perera, Marlon; Lawrentschuk, Nathan; Romanic, Diana; Papa, Nathan; Bolton, Damien

    2015-01-01

    Background Journal clubs are an essential tool in promoting clinical evidence-based medical education to all medical and allied health professionals. Twitter represents a public, microblogging forum that can facilitate traditional journal club requirements, while also reaching a global audience, and participation for discussion with study authors and colleagues. Objective The aim of the current study was to evaluate the current state of social media–facilitated journal clubs, specifically Twitter, as an example of continuing professional development. Methods A systematic review of literature databases (Medline, Embase, CINAHL, Web of Science, ERIC via ProQuest) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search of Twitter, the followers of identified journal clubs, and Symplur was also performed. Demographic and monthly tweet data were extracted from Twitter and Symplur. All manuscripts related to Twitter-based journal clubs were included. Statistical analyses were performed in MS Excel and STATA. Results From a total of 469 citations, 11 manuscripts were included and referred to five Twitter-based journal clubs (#ALiEMJC, #BlueJC, #ebnjc, #urojc, #meded). A Twitter-based journal club search yielded 34 potential hashtags/accounts, of which 24 were included in the final analysis. The median duration of activity was 11.75 (interquartile range [IQR] 19.9, SD 10.9) months, with 7 now inactive. The median number of followers and participants was 374 (IQR 574) and 157 (IQR 272), respectively. An overall increasing establishment of active Twitter-based journal clubs was observed, resulting in an exponential increase in total cumulative tweets (R 2=.98), and tweets per month (R 2=.72). Cumulative tweets for specific journal clubs increased linearly, with @ADC_JC, @EBNursingBMJ, @igsjc, @iurojc, and @NephJC, and showing greatest rate of change, as well as total impressions per month since

  5. Effect of changing journal clubs from traditional method to evidence-based method on psychiatry residents

    PubMed Central

    Faridhosseini, Farhad; Saghebi, Ali; Khadem-Rezaiyan, Majid; Moharari, Fatemeh; Dadgarmoghaddam, Maliheh

    2016-01-01

    Introduction Journal club is a valuable educational tool in the medical field. This method follows different goals. This study aims to investigate the effect on psychiatry residents of changing journal clubs from the traditional method to the evidence-based method. Method This study was conducted using a before–after design. First- and second-year residents of psychiatry were included in the study. First, the status quo was evaluated by standardized questionnaire regarding the effect of journal club. Then, ten sessions were held to familiarize the residents with the concept of journal club. After that, evidence-based journal club sessions were held. The questionnaire was given to the residents again after the final session. Data were analyzed through descriptive statistics (frequency and percentage frequency, mean and standard deviation), and analytic statistics (paired t-test) using SPSS 22. Results Of a total of 20 first- and second-year residents of psychiatry, the data of 18 residents were finally analyzed. Most of the subjects (17 [93.7%]) were females. The mean overall score before and after the intervention was 1.83±0.45 and 2.85±0.57, respectively, which showed a significant increase (P<0.001). Conclusion Moving toward evidence-based journal clubs seems like an appropriate measure to reach the goals set by this educational tool. PMID:27570469

  6. Burn center journal club promotes clinical research, continuing education, and evidence-based practice.

    PubMed

    Fowler, Laura; Gottschlich, Michele M; Kagan, Richard J

    2013-01-01

    The purpose of this study was to characterize the structure, policy, implementation, and outcome measures of a burn team journal club to assess its effectiveness in promoting multidisciplinary education relative to research competency, clinical knowledge, and evidence-based practice. After 2 years of a new multidisciplinary format, an anonymous quality assurance survey was distributed to staff members of a regional pediatric burn center to evaluate the impact of the journal club on clinical and research indicators. The 24 journal club meetings evaluated in this study included a variety of topics, among which were wound healing, infection, nutrition, metabolism, sleep, medications, alternative medicine, research compliance, and child abuse. The speakers included a variety of hospital personnel: 26% researchers, 23% physicians, 20% registered nurses, and 31% other disciplines and attendance mean was 29 participants per session (range 17-50). Survey results from 30 respondents indicated that 100% judged the program to be valuable to personal educational needs and 83% indicated that format did not warrant change. According to self-report data, the journal club enhanced medical knowledge (90%), patient care (73%), research competency (70%), critical thinking (63%), and evidence-based practice (63%). Results indicate that the journal club program was well received by participants, and promoted enhanced knowledge and improved patient care. In the future, barriers to research initiatives and integration of research findings into practice warrant follow-up study. Journal club should be incorporated into the learning curriculum of burn practitioners as a means to promote critical thinking, research competency, and evidence-based clinical practice. PMID:23519068

  7. Beyond journal clubs. Moving toward an integrated evidence-based medicine curriculum.

    PubMed

    Hatala, Rose; Keitz, Sheri A; Wilson, Mark C; Guyatt, Gordon

    2006-05-01

    Incorporating evidence-based medicine (EBM) into clinical practice is an important competency that residency training must address. Residency program directors, and the clinical educators who work with them, should develop curricula to enhance residents' capacity for independent evidence-based practice. In this article, the authors argue that residency programs must move beyond journal club formats to promote the practice of EBM by trainees. The authors highlight the limitations of journal club, and suggest additional curricular approaches for an integrated EBM curriculum. Helping residents become effective evidence users will require a sustained effort on the part of residents, faculty, and their educational institutions. PMID:16704406

  8. Twitter-Augmented Journal Club: Educational Engagement and Experience So Far.

    PubMed

    Udani, Ankeet D; Moyse, Daniel; Peery, Charles Andrew; Taekman, Jeffrey M

    2016-04-15

    Social media is a nascent medical educational technology. The benefits of Twitter include (1) easy adoption; (2) access to experts, peers, and patients across the globe; (3) 24/7 connectivity; (4) creation of virtual, education-based communities using hashtags; and (5) crowdsourcing information using retweets. We report on a novel Twitter-augmented journal club for anesthesia residents: its design, implementation, and impact. Our inaugural anesthesia Twitter-augmented journal club succeeded in engaging the anesthesia community and increasing residents' professional use of Twitter. Notably, our experience suggests that anesthesia residents are willing to use social media for their education. PMID:26579611

  9. Use of a Journal Club for Professional Development: Outcomes in a School-Based Occupational Therapy Practice

    ERIC Educational Resources Information Center

    Szucs, Kimberly A.; Benson, Jeryl D.; Corturillo, Amanda

    2016-01-01

    This article investigates the outcomes of a journal club on the evidence-based practice (EBP) skills of school-based practitioners. Participants' knowledge, attitudes, and perceptions of EBP were collected using pre- and postsurveys following 6 monthly journal club sessions. Participants identified time, availability of articles, and decreased…

  10. Journal Clubs and Case Conferences: From Academic Tradition to Communities of Practice

    ERIC Educational Resources Information Center

    Price, David W.; Felix, Kate G.

    2008-01-01

    Introduction: As small group learning sessions, Journal Clubs (JCs) and Case Conferences (CCs), if structured interactively, have potential as educational formats that can change practice. However, the degree to which these formats, as currently typically structured, lead to practice change is unknown. Methods: We used concepts of communities of…

  11. ICTs as Placed Resources in a Rural Kenyan Secondary School Journalism Club

    ERIC Educational Resources Information Center

    Kendrick, Maureen; Chemjor, Walter; Early, Margaret

    2012-01-01

    In this study, we draw on three interrelated concepts, i.e. placed resources, multiliteracies and the carnivalesque, to understand how information and communication technology (ICT) resources are taken up within the context of a print-based journalism club. Our research participants attend an under-resourced girls' residential secondary school in…

  12. Charting the Course for a Nursing Online Journal Club: Part II.

    PubMed

    Moonan, Marilyn; Bukoye, Bola; Clapp, Alison; Shermont, Herminia; O'Sullivan Oliveira, Joanne

    2016-01-01

    In a pediatric inpatient setting, an interdisciplinary team designed and implemented an online journal club to discuss current nursing trends and research, as well as to foster evidence-based practice. This article is Part II of a two-part series in which the implementation process is described. PMID:26790492

  13. Charting the Course for a Nursing Online Journal Club: Part I.

    PubMed

    Moonan, Marilyn; Bukoye, Bola; Clapp, Alison; Shermont, Herminia; Oliveira, Joanne O'Sullivan

    2015-12-01

    In a pediatric inpatient setting, an interdisciplinary team designed and implemented an online journal club to discuss current nursing trends and research and to foster evidence-based practice. This article is Part I of a two-part series in which the process will be described. PMID:26641151

  14. A Journal-Club-Based Class that Promotes Active and Cooperative Learning of Biology

    ERIC Educational Resources Information Center

    Kitazono, Ana A.

    2010-01-01

    A journal-club-based class has been developed to promote active and cooperative learning and expose seniors in biochemistry and cellular molecular biology to recent research in the field. Besides giving oral presentations, students also write three papers: one discussing an article of their own choosing and two, discussing articles presented by…

  15. Classroom Journal Club: Collaborative Study of Contemporary Primary Literature in the Biomechanics Classroom.

    PubMed

    Kuxhaus, Laurel; Corbiere, Nicole C

    2016-07-01

    Current engineering pedagogy primarily focuses on developing technical proficiency and problem solving skills; the peer-review process for sharing new research results is often overlooked. The use of a collaborative classroom journal club can engage students with the excitement of scientific discovery and the process of dissemination of research results, which are also important lifelong learning skills. In this work, a classroom journal club was implemented and a survey of student perceptions spanning three student cohorts was collected. In this collaborative learning activity, students regularly chose and discussed a recent biomechanics journal article, and were assessed based on specific, individual preparation tasks. Most student-chosen journal articles were relevant to topics discussed in the regular class lecture. Surveys assessed student perceptions of the activity. The survey responses show that, across all cohorts, students both enjoyed the classroom journal club and recognized it as an important learning experience. Many reported discussing their journal articles with others outside of the classroom, indicating good engagement. The results demonstrate that student engagement with primary literature can foster both technical knowledge and lifelong learning skills. PMID:26902674

  16. How to establish an interactive eConference and eJournal Club.

    PubMed

    Yang, Paul R; Meals, Roy A

    2014-01-01

    With our hand team scattered across several different locations, it is difficult to find a time to get together for our weekly didactic hand conference and monthly hand journal club. In addition, traffic and tight clinical schedules sometimes force conferences to start late or be canceled. Our solution was to set up an on-line conference. Using TeamViewer to host our conference and Skype to host our journal clubs, we experienced increased attendance by both faculty and residents in our meetings. In this article, we establish a method of hosting effective on-line videoconferences to facilitate nearly universal participation of our hand team, and we hope to assist others who wish to establish similar setups in their communities. PMID:24315487

  17. Refining the Journal Club Presentations of Postgraduate Students in Seven Clinical Departments for Better Evidence-based Practice

    PubMed Central

    Herur, A; Kolagi, S; Ramadurg, U; Hiremath, CS; Hadimani, CP; Goudar, SS

    2016-01-01

    Background: A gap between best practice and actual clinical care exists and this can be overcome by evidence-based practice (EBP), which is essential to improve the clinical decision making. A strategy to reduce deficits in care provision is to train the postgraduate students in the practice of EBP in the journal clubs as evidence from medical colleges in India reveals that current format of journal club presentations is unsatisfactory. Aim: The aim of the present study was to refine the journal club presentations of postgraduate students of clinical departments and to study the effectiveness of EBP training in them for better EBP. Subjects and Methods: This study was conducted in S. Nijalingappa Medical College, Bagalkot, Karnataka, India, and it was a pre- and post-trial. This study was a pre- and post-trial done during the journal club presentations of postgraduate students from clinical departments. Postgraduate students' understanding of concepts about EBP was assessed using Fresno test questionnaire in traditional journal club presentation. A hands-on session incorporating steps of EBP was imparted to them. Soon after the session, each student was assessed. In the next journal club presentation, 1 week later, the students were assessed again with the same questionnaire by the same faculty. Scores of the postgraduate students, before and after intervention (immediate and 1 week later), were compared. Data were analyzed by paired t-test using SPSS. Results: An increase in mean posttest scores was seen immediately and also 1 week later as compared to the pretest scores. The scores also increased significantly, when each step of EBP was considered. Conclusions: Incorporating teaching of EBP in journal club presentations improved the competencies of postgraduate students in clinical decision making. PMID:27398252

  18. Dietetic Professionals' Perceptions of the Learning Environment, Perceived Learning, and Actual Learning of Online and Face-to-Face Journal Clubs

    ERIC Educational Resources Information Center

    Schumacher, Julie Raeder

    2009-01-01

    A journal club is defined as a group of individuals who meet regularly to discuss current trends in literature and have been advocated to bridge the gap of research and practice. With the popularity of the Internet, there are a variety of tools available for online learning through journal clubs including asynchronous discussions, which the…

  19. A Journal Club Workshop that Teaches Undergraduates a Systematic Method for Reading, Interpreting, and Presenting Primary Literature

    ERIC Educational Resources Information Center

    Robertson, Katherine

    2012-01-01

    For success after graduation, science undergraduates must master a number of skills such as scientific literacy (interpretation and evaluation of primary research articles) and effective communication. Many researchers have recognized the benefits of journal clubs in developing such skills, and a large body of literature describes how they may be…

  20. Role of Evidence-Based Reviews in Surgery in teaching critical appraisal skills and in journal clubs

    PubMed Central

    Ahmadi, Negar; Dubois, Luc; McKenzie, Marg; Brown, Carl J.; MacLean, Anthony R.; McLeod, Robin S.

    2013-01-01

    Background Evidence-Based Reviews in Surgery (EBRS) is a program developed to teach critical appraisal skills to general surgeons and residents. The purpose of this study was to assess the use of EBRS by general surgery residents across Canada and to assess residents’ opinions regarding EBRS and journal clubs. Methods We surveyed postgraduate year 2–5 residents from 15 general surgery programs. Data are presented as percentages and means. Results A total of 231 residents (58%, mean 56% per program, range 0%–100%) responded: 172 (75%) residents indicated that they know about EBRS and that it is used in their programs. More than 75% of residents who use EBRS agreed or strongly agreed that the EBRS clinical and methodological articles and reviews are relevant. Only 55 residents (24%) indicated that they used EBRS online. Most residents (198 [86%]) attend journal clubs. The most common format is a mandatory meeting held at a special time every month with faculty members with epidemiological and clinical expertise. Residents stated that EBRS articles were used exclusively (13%) or in conjunction with other articles (57%) in their journal clubs. Most respondents (176 of 193 [91%]) stated that journal clubs are very or somewhat valuable to their education. Conclusion The EBRS program is widely used among general surgery residents across Canada. Although most residents who use EBRS rate it highly, a large proportion are unaware of EBRS online features. Thus, future efforts to increase awareness of EBRS online features and increase its accessibility are required. PMID:23883511

  1. Taking Journal Clubs off Autopilot: A Case Study of Teaching Literature Evaluation Skills to Preclinical MD/PhD Students

    PubMed Central

    Currier, Rebecca L.; Schneider, Marguerite Reid; Heubi, James E.

    2014-01-01

    Researchers designed learner-directed journal clubs to develop literature evaluation skills in preclinical students. Sessions balanced student-led discussion with structured objectives and faculty support. During the pilot with preclinical MD/PhD students, self-rated mastery improved over all 17 measured objectives. Six exercises have since been incorporated into the full medical school curriculum. PMID:24634798

  2. Using architectures for semantic interoperability to create journal clubs for emergency response

    SciTech Connect

    Powell, James E; Collins, Linn M; Martinez, Mark L B

    2009-01-01

    In certain types of 'slow burn' emergencies, careful accumulation and evaluation of information can offer a crucial advantage. The SARS outbreak in the first decade of the 21st century was such an event, and ad hoc journal clubs played a critical role in assisting scientific and technical responders in identifying and developing various strategies for halting what could have become a dangerous pandemic. This research-in-progress paper describes a process for leveraging emerging semantic web and digital library architectures and standards to (1) create a focused collection of bibliographic metadata, (2) extract semantic information, (3) convert it to the Resource Description Framework /Extensible Markup Language (RDF/XML), and (4) integrate it so that scientific and technical responders can share and explore critical information in the collections.

  3. Journal Club presentation in research orientation at Bahria University Medical & Dental College

    PubMed Central

    Rehman, Rehana; Rehan, Rabiya; Usmani, Ambreen

    2015-01-01

    Objective: To determine faculty perception on journal club (JC) presentation at Bahria University Medical and Dental College (BUMDC), Karachi. Pakistan. Methods: It was a cross sectional study conducted from January 2009 to December 2012 to acquire faculty member’s feedback on JC presentations in structured meeting at BUMDC. Feedback was acquired by a self-reported questionnaire on a 3-pt Likert scale with a score of 1= disagree, 2= neutral, 3 = agree. Respondents were divided into Group I; senior faculty (professors, associates and assistants) and Group II of junior faculty (lecturers). Chi square test was applied to compare categorical variables; results considered significant with p value< 0.05. Result: A total of 75JC presentations were made in study period. In Group I, response was acquired by 5 Professors, 3 Associate Professors and 7 Assistant Professors whereas 34 lecturers comprised of Group II. Both groups responded to usefulness of JC equally without any significant difference. JC encouraged literature search in 35(72%), enabled 38(78%) to recall their knowledge and 34(70%) to understand study objectives. The participants 34(70%) were able to comprehend research methodology, 19(38%) understood biostatistics and 29(59%) evaluated the paper critically. The exercise motivated 36(74%) and 30(62%) participants were able to design their research projects. Conclusions: Orientation of research at BUMDC was made possible by JC discussions which encouraged literature review from reputable journals, understanding of research methodology and critical appraisals that facilitated formulation of research plans. PMID:25878630

  4. Implementing a journal club in a palliative care setting: a link in the chain of evidence-based practice.

    PubMed

    O'Connor, Lera; Bennett, Peter; Gardner, Anne; Hawkins, Mary T; Wellman, David

    2009-01-01

    This paper describes the implementation and evaluation of a journal club in a privately funded palliative care unit. Journal club meetings were initiated as part of a quality improvement process to foster the uptake of evidence-based practice. Nurses were presented with research articles each month and discussions were conducted focussing on methodological considerations of the research and implications of the research for patient care. The maximum number of attendees at any one meeting was nine and the minimum number was four. Overall, evaluations were positive about all aspects of the meetings. Attendees found that the selected articles were relevant, providing new information, stimulated discussion and reflection on clinical practice and encouraged further reading. One of the positive aspects of the meetings identified by participants was the facilitation style that enabled discussion in a safe and supportive environment. An important outcome of the meetings is the potential to explore evidence-based practices relevant to palliative care and to implement new practices or revise existing ones. As part of this process practice changes and clinical guidelines have been implemented. A dedicated facilitator with university links and a supportive organisational culture promoted club meetings as a practical way to provide clinical nurses with the opportunity to explore evidence-based research in the area of palliative care. PMID:19831148

  5. The use of a virtual learning environment in promoting virtual journal clubs and case-based discussions in trauma and orthopaedic postgraduate medical education: the Leicester experience.

    PubMed

    Palan, J; Roberts, V; Bloch, B; Kulkarni, A; Bhowal, B; Dias, J

    2012-09-01

    The use of journal clubs and, more recently, case-based discussions in order to stimulate debate among orthopaedic surgeons lies at the heart of orthopaedic training and education. A virtual learning environment can be used as a platform to host virtual journal clubs and case-based discussions. This has many advantages in the current climate of constrained time and diminishing trainee and consultant participation in such activities. The virtual environment model opens up participation and improves access to journal clubs and case-based discussions, provides reusable educational content, establishes an electronic record of participation for individuals, makes use of multimedia material (including clinical imaging and photographs) for discussion, and finally, allows participants to link case-based discussions with relevant papers in the journal club. The Leicester experience highlights the many advantages and some of the potential difficulties in setting up such a virtual system and provides useful guidance for those considering such a system in their own training programme. As a result of the virtual learning environment, trainee participation has increased and there is a trend for increased consultant input in the virtual journal club and case-based discussions. It is likely that the use of virtual environments will expand to encompass newer technological approaches to personal learning and professional development. PMID:22933486

  6. Evidence-based Medicine versus the Conventional Approach to Journal Club Sessions: Which One Is More Successful in Teaching Critical Appraisal Skills?

    PubMed

    Alavi-Moghaddam, Mostafa; Yazdani, Shahram; Mortazavi, Fathie; Chichi, Samira; Hosseini-Zijoud, Seyed-Mostafa

    2016-05-01

    This study aimed to compare evidence-based medicine (EBM) vs. conventional approaches to journal club sessions in teaching critical appraisal skills in reading papers by emergency medicine residents. This double cut off discontinuation regression quasi-experimental study was conducted among emergency medicine residents. EBM vs. the conventional approach were applied to teach critical appraisal skills for half of the residents as an experimental group and another half as a control group respectively. Both groups participated in one hour monthly journal club sessions for six months. Before and after the study, all participants were examined by two tests: the Fresno Test (FT) [to evaluate their knowledge about EBM] and the Critical Appraisal Skills Test (CAST) [to evaluate their competency with critical appraisal skills]. The allocation of the participants into the experimental or control groups was according to their CAST scores before the study. 50 emergency medicine residents participated. After the study, the scores of both groups in the FT and CAST significantly improved (p<0.01), and the promotion of scores of the FT and CAST in the experimental group were more than that of the conventional group (p<0.0001). The current study indicated that an evidence-based medicine approach in journal club sessions was comparatively more advantageous compared to the conventional approach in teaching critical appraisal skills for reading papers among the residents of emergency medicine. PMID:27231674

  7. Evidence-based Medicine versus the Conventional Approach to Journal Club Sessions: Which One Is More Successful in Teaching Critical Appraisal Skills?

    PubMed Central

    Alavi-Moghaddam, Mostafa; Yazdani, Shahram; Mortazavi, Fathie; Chichi, Samira

    2016-01-01

    This study aimed to compare evidence-based medicine (EBM) vs. conventional approaches to journal club sessions in teaching critical appraisal skills in reading papers by emergency medicine residents. This double cut off discontinuation regression quasi-experimental study was conducted among emergency medicine residents. EBM vs. the conventional approach were applied to teach critical appraisal skills for half of the residents as an experimental group and another half as a control group respectively. Both groups participated in one hour monthly journal club sessions for six months. Before and after the study, all participants were examined by two tests: the Fresno Test (FT) [to evaluate their knowledge about EBM] and the Critical Appraisal Skills Test (CAST) [to evaluate their competency with critical appraisal skills]. The allocation of the participants into the experimental or control groups was according to their CAST scores before the study. 50 emergency medicine residents participated. After the study, the scores of both groups in the FT and CAST significantly improved (p<0.01), and the promotion of scores of the FT and CAST in the experimental group were more than that of the conventional group (p<0.0001). The current study indicated that an evidence-based medicine approach in journal club sessions was comparatively more advantageous compared to the conventional approach in teaching critical appraisal skills for reading papers among the residents of emergency medicine. PMID:27231674

  8. Rich-club and page-club coefficients for directed graphs

    NASA Astrophysics Data System (ADS)

    Smilkov, Daniel; Kocarev, Ljupco

    2010-06-01

    Rich-club and page-club coefficients and their null models are introduced for directed graphs. Null models allow for a quantitative discussion of the rich-club and page-club phenomena. These coefficients are computed for four directed real-world networks: Arxiv High Energy Physics paper citation network, Web network (released from Google), Citation network among US Patents, and email network from a EU research institution. The results show a high correlation between rich-club and page-club ordering. For journal paper citation network, we identify both rich-club and page-club ordering, showing that “elite” papers are cited by other “elite” papers. Google web network shows partial rich-club and page-club ordering up to some point and then a narrow declining of the corresponding normalized coefficients, indicating the lack of rich-club ordering and the lack of page-club ordering, i.e. high in-degree (PageRank) pages purposely avoid sharing links with other high in-degree (PageRank) pages. For UC patents citation network, we identify page-club and rich-club ordering providing a conclusion that “elite” patents are cited by other “elite” patents. Finally, for email communication network we show lack of both rich-club and page-club ordering. We construct an example of synthetic network showing page-club ordering and the lack of rich-club ordering.

  9. Club Drugs

    MedlinePlus

    ... Rohypnol, ketamine, as well as MDMA (ecstasy) and methamphetamine ( Drug Facts: Club Drugs , National Institute on Drug ... Club Drugs , National Institute on Drug Abuse, 2010). Methamphetamine is a powerfully addictive stimulant associated with serious ...

  10. Development of an ACP facility

    SciTech Connect

    Gil-Sung You; Won-Myung Choung; Jeong-Hoe Ku; il-Je Cho; Dong-Hak Kook; Kie-Chan Kwon; Eun-Pyo Lee; Ji-Sup Yoon; Seong-Won Park; Won-Kyung Lee

    2007-07-01

    KAERI has been developing an advanced spent fuel conditioning process (ACP). The ACP facility for a process demonstration consists of two air-sealed type hot cells. The safety analysis results showed that the facility was designed safely. The relevant integrated performance tests were also carried out successfully. (authors)

  11. Global Emergency Medicine Journal Club: A Social Media Discussion About the Outpatient Management of Patients With Spontaneous Pneumothorax by Using Pigtail Catheters.

    PubMed

    Trueger, N Seth; Murray, Heather; Kobner, Scott; Lin, Michelle

    2015-10-01

    Annals of Emergency Medicine collaborated with an educational Web site, Academic Life in Emergency Medicine (ALiEM) to host a public discussion featuring the 2014 Annals article on the outpatient management of patients with a spontaneous pneumothorax by using pigtail catheters. The objective was to curate a 14-day (November 10 to 23, 2014) worldwide academic dialogue among clinicians about the article. Four online facilitators hosted the multimodal discussion on the ALiEM Web site, Twitter, and Google Hangout. Comments across the social media platforms were curated for this report, as framed by 4 preselected questions. Engagement was tracked through Web analytic tools. Blog comments, tweets, and video expert commentary involving the featured article are summarized and reported. The dialogue resulted in 1,023 page views from 347 cities in 49 countries on the ALiEM Web site, 279,027 Twitter impressions, and 88 views of the video interview with experts. This Global Emergency Medicine Journal Club created a virtual community of practice from around the world and identified common themes around the management of spontaneous pneumothorax, which included substantial practice variation in regard to inpatient versus outpatient management, location of chest tube, the use of aspiration, and chest radiography after placement. PMID:26059486

  12. Digital clubbing

    PubMed Central

    Sarkar, Malay; Mahesh, D. M.; Madabhavi, Irappa

    2012-01-01

    Digital clubbing is an ancient and important clinical signs in medicine. Although clubbed fingers are mostly asymptomatic, it often predicts the presence of some dreaded underlying diseases. Its exact pathogenesis is not known, but platelet-derived growth factor and vascular endothelial growth factor are recently incriminated in its causation. The association of digital clubbing with various disease processes and its clinical implications are discussed in this review. PMID:23243350

  13. Culture Clubs.

    ERIC Educational Resources Information Center

    Gersten, Bridget Fitzgerald

    1998-01-01

    One way to break down barriers and promote understanding among English-as-a-Second-Language (ESL) and mainstream students is to establish culture clubs. Culture clubs involve frequent exchange of information about social, academic, and cultural topics in extracurricular settings. They are a critical component of ESL programs. The article explains…

  14. Club Drugs

    MedlinePlus

    ... uses. Other uses of these drugs are abuse. Club drugs are also sometimes used as "date rape" drugs, to make someone unable to say no to or fight back against sexual assault. Abusing these drugs can ...

  15. [Club drugs].

    PubMed

    Guerreiro, Diogo Frasquilho; Carmo, Ana Lisa; da Silva, Joaquim Alves; Navarro, Rita; Góis, Carlos

    2011-01-01

    Club drugs are the following substances: Methylenedioxymethamphetamine (MDMA); Methamphetamine; Lysergic Acid Diethylamide (LSD); Ketamine; Gamma-hydroxybutyrate (GHB) and Flunitrazepam. These substances are mainly used by adolescents and young adults, mostly in recreational settings like dance clubs and rave parties. These drugs have diverse psychotropic effects, are associated with several degrees of toxicity, dependence and long term adverse effects. Some have been used for several decades, while others are relatively recent substances of abuse. They have distinct pharmacodynamic and pharmacokinetic properties, are not easy to detect and, many times, the use of club drugs is under diagnosed. Although the use of these drugs is increasingly common, few health professionals feel comfortable with the diagnosis and treatment. The authors performed a systematic literature review, with the goal of synthesising the existing knowledge about club drugs, namely epidemiology, mechanism of action, detection, adverse reactions and treatment. The purpose of this article is creating in Portuguese language a knowledge data base on club drugs, that health professionals of various specialties can use as a reference when dealing with individual with this kind of drug abuse. PMID:22525626

  16. Modified acyl-ACP desaturase

    DOEpatents

    Cahoon, Edgar B.; Shanklin, John; Lindgvist, Ylva; Schneider, Gunter

    1998-01-06

    Disclosed is a methods for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.

  17. Modified Acyl-ACP desaturase

    DOEpatents

    Cahoon, Edgar B.; Shanklin, John; Lindqvist, Ylva; Schneider, Gunter

    1999-03-30

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.

  18. Mannose 6 Dephosphorylation of Lysosomal Proteins Mediated by Acid Phosphatases Acp2 and Acp5

    PubMed Central

    Makrypidi, Georgia; Damme, Markus; Müller-Loennies, Sven; Trusch, Maria; Schmidt, Bernhard; Schlüter, Hartmut; Heeren, Joerg; Lübke, Torben; Saftig, Paul

    2012-01-01

    Mannose 6-phosphate (Man6P) residues represent a recognition signal required for efficient receptor-dependent transport of soluble lysosomal proteins to lysosomes. Upon arrival, the proteins are rapidly dephosphorylated. We used mice deficient for the lysosomal acid phosphatase Acp2 or Acp5 or lacking both phosphatases (Acp2/Acp5−/−) to examine their role in dephosphorylation of Man6P-containing proteins. Two-dimensional (2D) Man6P immunoblot analyses of tyloxapol-purified lysosomal fractions revealed an important role of Acp5 acting in concert with Acp2 for complete dephosphorylation of lysosomal proteins. The most abundant lysosomal substrates of Acp2 and Acp5 were identified by Man6P affinity chromatography and mass spectrometry. Depending on the presence of Acp2 or Acp5, the isoelectric point of the lysosomal cholesterol-binding protein Npc2 ranged between 7.0 and 5.4 and may thus regulate its interaction with negatively charged lysosomal membranes at acidic pH. Correspondingly, unesterified cholesterol was found to accumulate in lysosomes of cultured hepatocytes of Acp2/Acp5−/− mice. The data demonstrate that dephosphorylation of Man6P-containing lysosomal proteins requires the concerted action of Acp2 and Acp5 and is needed for hydrolysis and removal of degradation products. PMID:22158965

  19. Star Clubbing

    ERIC Educational Resources Information Center

    Hogan, Maria; Davis, Sarah

    2011-01-01

    Despite the rewards, there are numerous barriers to teachers running clubs: (1) getting weekly fresh activity ideas and resourcing them; (2) the lack of a budget; and (3) shortage of time. With the best will in the world, it is easy to feel that time is already swallowed up with planning and assessment of normal lessons, let alone putting in the…

  20. Modified Acyl-ACP desaturase

    DOEpatents

    Cahoon, E.B.; Shanklin, J.; Lindqvist, Y.; Schneider, G.

    1999-03-30

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity. 2 figs.

  1. Modified acyl-ACP desaturase

    DOEpatents

    Cahoon, E.B.; Shanklin, J.; Lindgvist, Y.; Schneider, G.

    1998-01-06

    Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity. 1 fig.

  2. Join This Cool Club!

    ERIC Educational Resources Information Center

    Novelli, Joan

    1995-01-01

    Students can study the Arctic by creating Arctic clubs, using modems to communicate with students nationwide who are following International Arctic Project (IAP) explorers. The article describes the IAP, explains how to form a club, and discusses issues that clubs can tackle, for example, pollution, Arctic animals, natural resources, and the…

  3. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... be subject to, the regulations for ACP contracts and the ACP program that were contained in the 7 CFR... 7 Agriculture 7 2012-01-01 2012-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION...

  4. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... be subject to, the regulations for ACP contracts and the ACP program that were contained in the 7 CFR... 7 Agriculture 7 2014-01-01 2014-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION...

  5. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... be subject to, the regulations for ACP contracts and the ACP program that were contained in the 7 CFR... 7 Agriculture 7 2011-01-01 2011-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION...

  6. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... be subject to, the regulations for ACP contracts and the ACP program that were contained in the 7 CFR... 7 Agriculture 7 2013-01-01 2013-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION...

  7. 7 CFR 701.44 - Agricultural Conservation Program (ACP) contracts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... regulations for ACP contracts and the ACP program that were contained in the 7 CFR, parts 700 to 899, edition... 7 Agriculture 7 2010-01-01 2010-01-01 false Agricultural Conservation Program (ACP) contracts. 701... AGENCY, DEPARTMENT OF AGRICULTURE AGRICULTURAL CONSERVATION PROGRAM EMERGENCY CONSERVATION PROGRAM...

  8. Multimodal Learning Clubs

    ERIC Educational Resources Information Center

    Casey, Heather

    2012-01-01

    Multimodal learning clubs link principles of motivation and engagement with 21st century technological tools and texts to support content area learning. The author describes how a sixth grade health teacher and his class incorporated multimodal learning clubs into a unit of study on human body systems. The students worked collaboratively online…

  9. The Book Club Exploded

    ERIC Educational Resources Information Center

    Hoffert, Barbara

    2006-01-01

    One leader, 12 readers, and a few well-thumbed copies of Jane Austen's "Pride and Prejudice." That is all a book club once required, but this is no longer the case. This article describes how the runaway popularity of book clubs has brought with it a whole new set of possibilities. Thematic discussion? A fiction/nonfiction mix? Videoconferencing?…

  10. Boys & Girls Clubs of America

    MedlinePlus

    ... Now Corporation for National and Community Service and Boys & Girls Clubs of America partner with Google to help ... Military Youth Arianna Skinner Receives Top Honor from Boys & Girls Clubs of America JB MDL- Fort Dix Youth ...

  11. Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP

    PubMed Central

    Luo, Qixia; Li, Meng; Fu, Huihui; Meng, Qiu; Gao, Haichun

    2016-01-01

    It is established that Escherichia coli β-ketoacyl-ACP synthase (KAS) I (encoded by EcfabB) is the primary, if not exclusive, factor for elongation of the cis-3-decenoyl-ACP (C10:1-ACP) but not effective with C16:1- or longer-chain-ACPs. To test the extent to which these features apply to KAS I proteins in other species, in this study, we examined the physiological role of FabB in Shewanella oneidensis, an excellent model for researching type II fatty acid synthetic (FAS) system and its regulation. We showed that the loss of either FabA (the enzyme that introduces double bond) or FabB, in the absence of DesA which desaturizes C16 and C18 to generate respective C16:1 and C18:1, leads to a UFA auxotroph. However, fatty acid profiles of membrane phospholipid of the fabA and fabB mutants are significantly different, suggesting that FabB participates in steps beyond elongation of C10:1-ACP. Further analyses demonstrated that S. oneidensis FabB differs from EcFabB in that (i) it is not the only enzyme capable of catalyzing elongation of the cis-3-decenoyl-ACP produced by FabA, (ii) it plays a critical role in elongation of C16:1- and longer-chain-ACPs, and (iii) its overproduction is detrimental. PMID:27014246

  12. The ACP (Advanced Computer Program) Branch bus and real-time applications of the ACP multiprocessor system

    SciTech Connect

    Hance, R.; Areti, H.; Atac, R.; Biel, J.; Cook, A.; Fischler, M.; Gaines, I.; Husby, D.; Nash, T.; Zmuda, T.

    1987-05-08

    The ACP Branchbus, a high speed differential bus for data movement in multiprocessing and data acquisition environments, is described. This bus was designed as the central bus in the ACP multiprocessing system. In its full implementation with 16 branches and a bus switch, it will handle data rates of 160 MByte/sec and allow reliable data transmission over inter rack distances. We also summarize applications of the ACP system in experimental data acquisition, triggering and monitoring, with special attention paid to FASTBUS environments.

  13. The Kindergarten Club.

    ERIC Educational Resources Information Center

    Palmore, Elaine Mitchell

    1999-01-01

    Describes the development of an after-school club for kindergarten-age children enrolled in a Montessori preschool program in Nashville, Tennessee. Activity units included performing a play of Sendak's "Where the Wild Things Are," studying country music and writing songs, and holding a dinner for the children's parents. (KB)

  14. The smallest study club.

    PubMed

    Sauget, Earl

    2002-01-01

    A specialist on Guam describes a study club of specialists on the island. Although the number of participants is small in absolute terms, the group's monthly meetings centered around cases serves the functions of stimulating currency and self learning and enhances coordination of complex treatment cases. PMID:12602217

  15. The Other Club Scene

    ERIC Educational Resources Information Center

    Davis, Noah

    2007-01-01

    At colleges nationwide, students from diverse racial, cultural and socioeconomic backgrounds meet and befriend each other under the auspices of club sports. Adam Pruett, the recreational sports coordinator at the University of California, Los Angeles, says any cultural uneasiness is overcome by the students' shared passion for the particular…

  16. Composite Golf Clubs

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Babcock & Wilcox Co. under a partnership with Marshall Space Flight Center, produced composite materials, originally from the shuttle program, for improving golf clubs. Company used Marshall Space Flight Center's data summary file summarizing typical processing techniques and mechanical and physical properties of graphite and boron- reinforced composite materials. Reinforced composites provide combination of shaft rigidity and flexibility that provide maximum distance.

  17. The Interactions of CPP–ACP with Saliva

    PubMed Central

    Huq, Noorjahan Laila; Myroforidis, Helen; Cross, Keith J.; Stanton, David P.; Veith, Paul D.; Ward, Brent R.; Reynolds, Eric C.

    2016-01-01

    The repair of early dental caries lesions has been demonstrated by the application of the remineralisation technology based on casein phosphopeptide-stabilised amorphous calcium phosphate complexes (CPP–ACP). These complexes consist of an amorphous calcium phosphate mineral phase stabilised and encapsulated by the self-assembly of milk-derived phosphopeptides. During topical application of CPP–ACP complexes in the oral cavity, the CPP encounters the enamel pellicle consisting of salivary proteins and peptides. However the interactions of the CPP with the enamel salivary pellicle are not known. The studies presented here reveal that the predominant peptides of CPP–ACP complexes do interact with specific salivary proteins and peptides of the enamel pellicle, and provide a mechanism by which the CPP–ACP complexes are localised at the tooth surface to promote remineralisation. PMID:27294918

  18. The Interactions of CPP-ACP with Saliva.

    PubMed

    Huq, Noorjahan Laila; Myroforidis, Helen; Cross, Keith J; Stanton, David P; Veith, Paul D; Ward, Brent R; Reynolds, Eric C

    2016-01-01

    The repair of early dental caries lesions has been demonstrated by the application of the remineralisation technology based on casein phosphopeptide-stabilised amorphous calcium phosphate complexes (CPP-ACP). These complexes consist of an amorphous calcium phosphate mineral phase stabilised and encapsulated by the self-assembly of milk-derived phosphopeptides. During topical application of CPP-ACP complexes in the oral cavity, the CPP encounters the enamel pellicle consisting of salivary proteins and peptides. However the interactions of the CPP with the enamel salivary pellicle are not known. The studies presented here reveal that the predominant peptides of CPP-ACP complexes do interact with specific salivary proteins and peptides of the enamel pellicle, and provide a mechanism by which the CPP-ACP complexes are localised at the tooth surface to promote remineralisation. PMID:27294918

  19. Selection on the Drosophila seminal fluid protein Acp62F

    PubMed Central

    Wong, Alex; Rundle, Howard

    2013-01-01

    Sperm competition and sexual conflict are thought to underlie the rapid evolution of reproductive proteins in many taxa. While comparative data are generally consistent with these hypotheses, few manipulative tests have been conducted and those that have provided contradictory results in some cases. Here, we use both comparative and experimental techniques to investigate the evolution of the Drosophila melanogaster seminal fluid protein Acp62F, a protease inhibitor for which extensive functional tests have yielded ambiguous results. Using between-species sequence comparisons, we show that Acp62F has been subject to recurrent positive selection. In addition, we experimentally evolved populations polymorphic for an Acp62F null allele over eight generations, manipulating the opportunities for natural and sexual selection. We found that the Acp62F null allele increased in frequency in the presence of natural selection, with no effect of sexual selection. PMID:23919141

  20. 26 CFR 1.401(m)-2 - ACP test.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... satisfy the ACP test, but not in excess of 100%. In this case, an increase in the match rate from 50% to... under the ACP test only to the extent they do not exceed 25.00% of compensation. In this case, all of... determined under § 1.401(m)-2(b)(2)(iv) (as it appeared in the April 1, 2007, edition of 26 CFR part 1)....

  1. Substrate Recognition by β-Ketoacyl-ACP Synthases†

    PubMed Central

    Borgaro, Janine G.; Chang, Andrew; Machutta, Carl A.; Zhang, Xujie; Tonge, Peter J.

    2011-01-01

    β-Ketoacyl-ACP synthase (KAS) enzymes catalyze Claisen condensation reactions in the fatty acid biosynthesis pathway. These reactions follow a ping-pong mechanism in which a donor substrate acylates the active site cysteine residue after which the acyl group is condensed with the malonyl-ACP acceptor substrate to form a β-ketoacyl-ACP. In the priming KASIII enzymes the donor substrate is an acyl-CoA while in the elongating KASI and KASII enzymes the donor is an acyl-ACP. Although the KASIII enzyme in Escherichia coli (ecFabH) is essential, the corresponding enzyme in Mycobacterium tuberculosis (mtFabH) is not, suggesting that the KASI or II enzyme in M. tuberculosis (KasA or KasB, respectively) must be able to accept a CoA donor substrate. Since KasA is essential, the substrate specificity of this KASI enzyme has been explored using substrates based on phosphopantetheine, CoA, ACP and AcpM peptide mimics. This analysis has been extended to the KASI and KASII enzymes from E. coli (ecFabB and ecFabF) where we show that a 14 residue malonyl-phosphopantetheine peptide can efficiently replace malonyl-ecACP as the acceptor substrate in the ecFabF reaction. While ecFabF is able to catalyze the condensation reaction when CoA is the carrier for both substrates, the KASI enzymes ecFabB and KasA have an absolute requirement for an ACP substrate as the acyl donor. Provided that this requirement is met, variation in the acceptor carrier substrate has little impact on the kcat/Km for the KASI reaction. For the KASI enzymes we propose that the binding of ecACP (AcpM) results in a conformational change that leads to an open form of the enzyme to which the malonyl acceptor substrate binds. Finally, the substrate inhibition observed when palmitoyl-CoA is the donor substrate for the KasA reaction has implications for the importance of mtFabH in the mycobacterial FASII pathway. PMID:22017312

  2. Substrate recognition by β-ketoacyl-ACP synthases.

    PubMed

    Borgaro, Janine G; Chang, Andrew; Machutta, Carl A; Zhang, Xujie; Tonge, Peter J

    2011-12-13

    β-Ketoacyl-ACP synthase (KAS) enzymes catalyze Claisen condensation reactions in the fatty acid biosynthesis pathway. These reactions follow a ping-pong mechanism in which a donor substrate acylates the active site cysteine residue after which the acyl group is condensed with the malonyl-ACP acceptor substrate to form a β-ketoacyl-ACP. In the priming KASIII enzymes the donor substrate is an acyl-CoA while in the elongating KASI and KASII enzymes the donor is an acyl-ACP. Although the KASIII enzyme in Escherichia coli (ecFabH) is essential, the corresponding enzyme in Mycobacterium tuberculosis (mtFabH) is not, suggesting that the KASI or II enzyme in M. tuberculosis (KasA or KasB, respectively) must be able to accept a CoA donor substrate. Since KasA is essential, the substrate specificity of this KASI enzyme has been explored using substrates based on phosphopantetheine, CoA, ACP, and AcpM peptide mimics. This analysis has been extended to the KASI and KASII enzymes from E. coli (ecFabB and ecFabF) where we show that a 14-residue malonyl-phosphopantetheine peptide can efficiently replace malonyl-ecACP as the acceptor substrate in the ecFabF reaction. While ecFabF is able to catalyze the condensation reaction when CoA is the carrier for both substrates, the KASI enzymes ecFabB and KasA have an absolute requirement for an ACP substrate as the acyl donor. Provided that this requirement is met, variation in the acceptor carrier substrate has little impact on the k(cat)/K(m) for the KASI reaction. For the KASI enzymes we propose that the binding of ecACP (AcpM) results in a conformational change that leads to an open form of the enzyme to which the malonyl acceptor substrate binds. Finally, the substrate inhibition observed when palmitoyl-CoA is the donor substrate for the KasA reaction has implications for the importance of mtFabH in the mycobacterial FASII pathway. PMID:22017312

  3. Memory Golf Clubs

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Memory Corporation's investigation of shape memory effect, stemming from Marshall Space Flight Center contracts to study materials for the space station, has aided in the development of Zeemet, a proprietary, high-damping shape memory alloy for the golf industry. The Nicklaus Golf Company has created a new line of golf clubs using Zeemet inserts. Its superelastic and high damping attributes translate into more spin on the ball, greater control, and a solid feel.

  4. Level up Book Club

    ERIC Educational Resources Information Center

    LaGarde, Jennifer; Winner, Matthew C.

    2012-01-01

    Like all great ideas, Level Up Book Club grew out of a genuine need, the spontaneous firing of a few brain sparks, and the kind of luck that comes from being "in the right place at the right time." By mid-June 2011 the authors were already "bona fide" wonder twins--two educators who, although they'd never met, had stumbled upon each other through…

  5. Adventures with a High School Book Club

    ERIC Educational Resources Information Center

    McKee, Beverly

    2005-01-01

    A library media specialist writes about high school book clubs describing about setting the administration, dealing with logistics, recruiting members, choosing the right books, reaping the benefits, publicizing the club and reaching out to other clubs.

  6. Methamphetamine Use in Club Subcultures

    PubMed Central

    Kelly, Brian C.; LeClair, Amy; Parsons, Jeffrey T.

    2014-01-01

    In recent decades, methamphetamine developed a peculiar geographic distribution in the United States, with limited diffusion in the Northeast. While use within gay clubs received attention, methamphetamine in club subcultures more broadly remains less clear. Using quantitative and qualitative data, we provide a descriptive assessment of methamphetamine use in club subcultures. Methamphetamine use in club subcultures often has instrumental purposes. The context of initiation into methamphetamine use and its close connection to cocaine shape later patterns of use. Viewing meth solely as a gay party drug misses a significant part of the population and may misguide public health strategies to reduce methamphetamine use in the Northeast. PMID:23848380

  7. Mode of action of anticancer peptides (ACPs) from amphibian origin.

    PubMed

    Oelkrug, Christopher; Hartke, Martin; Schubert, Andreas

    2015-02-01

    Although cancer belongs to one of the leading causes of death around the world, fortunately studies have shown that tumor cells have various targets that are susceptible to attack. Interestingly, tumor cells are comprised of cellular membranes, which are altered in chemical composition relative to non-neoplastic cells, giving them an increased net negative charge. These altered membranes are ideal targets for antimicrobial peptides (AMPs) shown to have additional tumoricidal properties and, hence, named anticancer peptides (ACPs). Several hundred ACPs have been explored in vitro and in vivo on various types of cancer. Novel anticancer agents are supposed not to cause serious side effects and the formation of multidrug-resistant tumor cells. During the quest for potent ACPs, promising candidates were isolated from skin secretions of amphibians, such as the granular glands of the Chinese brown frog, Rana chensinensis. ACPs have to be selective to cancer cells and should not induce strong immune responses or be cleared from the body rapidly. Several modifications can improve ACPs either by optimizing the primary structure rationally or randomly or even by introducing other chemical modifications. PMID:25667440

  8. Book Clubbing! Successful Book Clubs for Young People

    ERIC Educational Resources Information Center

    Littlejohn, Carol

    2011-01-01

    This practical guide demonstrates how to sponsor a successful, student-led book club for grades K through 12 that is fun, easy-to-implement, and encourages reading. Establishing a book club for children and young people that's self-sustaining and successful long-term is a challenge that this book addresses and conquers. According to recent…

  9. ACP research and scientific coordination: Annual performance report

    SciTech Connect

    Hales, J.M.

    1992-09-17

    This research grant addresses two primary objectives: 1. Conduct of specific research tasks under the DOE Atmospheric Chemistry Program (ACP), and 2. Provision of scientific coordination for the Atmospheric Chemistry Program. In summary, the project is progressing essentially as expected, with some minor exceptions. Higher than anticipated demands within Objective 2, associated primarily with the ACP Ozone Project and the recompetition of the National Laboratories protion of ACP, have resulted in a somewhat higher proportionate emphasis on the coordination activities associated with this objective. Also, the immediate need for pre-campaign modeling of the North Pacific has resulted in an acceleration of the Pacific modeling task relative to other tasks, particularly the Atlantic modeling task. Modeling activities in general have been delayed somewhat because of the noted Objective 2 demands and because of the extended time that was necessary to complete financial agreements for this grant.

  10. Palmitoyl-acyl carrier protein (ACP) thioesterase and the evolutionary origin of plant acyl-ACP thioesterases.

    PubMed Central

    Jones, A; Davies, H M; Voelker, T A

    1995-01-01

    Acyl-acyl carrier protein (ACP) thioesterases play an essential role in chain termination during de novo fatty acid synthesis and in the channeling of carbon flux between the two lipid biosynthesis pathways in plants. We have discovered that there are two distinct but related thioesterase gene classes in higher plants, termed FatA and FatB, whose evolutionary divergence appears to be ancient. FatA encodes the already described 18:1-ACP thioesterase. In contrast, FatB representatives encode thioesterases preferring acyl-ACPs having saturated acyl groups. We unexpectedly obtained a 16:0-ACP thioesterase cDNA from Cuphea hookeriana seed, which accumulate predominantly 8:0 and 10:0. The 16:0 thioesterase transcripts were found in non-seed tissues, and expression in transgenic Brassica napus led to the production of a 16:0-rich oil. We present evidence that this type of FatB gene is ancient and ubiquitous in plants and that specialized plant medium-chain thioesterases have evolved independently from such enzymes several times during angiosperm evolution. Also, the ubiquitous 18:1-ACP thioesterase appears to be a derivative of a 16:0 thioesterase. PMID:7734968

  11. Evolution of acyl-ACP-thioesterases and β-ketoacyl-ACP-synthases revealed by protein-protein interactions

    PubMed Central

    Beld, Joris; Blatti, Jillian L.; Behnke, Craig; Mendez, Michael; Burkart, Michael D.

    2014-01-01

    The fatty acid synthase (FAS) is a conserved primary metabolic enzyme complex capable of tolerating cross-species engineering of domains for the development of modified and overproduced fatty acids. In eukaryotes, acyl-acyl carrier protein thioesterases (TEs) off-load mature cargo from the acyl carrier protein (ACP), and plants have developed TEs for short/medium-chain fatty acids. We showed that engineering plant TEs into the green microalga Chlamydomonas reinhardtii does not result in the predicted shift in fatty acid profile. Since fatty acid biosynthesis relies on substrate recognition and protein-protein interactions between the ACP and its partner enzymes, we hypothesized that plant TEs and algal ACP do not functionally interact. Phylogenetic analysis revealed major evolutionary differences between FAS enzymes, including TEs and ketoacyl synthases (KSs), in which the former is present only in some species, whereas the latter is present in all, and has a common ancestor. In line with these results, TEs appeared to be selective towards their ACP partners whereas KSs showed promiscuous behavior across bacterial, plant and algal species. Based on phylogenetic analyses, in silico docking, in vitro mechanistic crosslinking and in vivo algal engineering, we propose that phylogeny can predict effective interactions between ACPs and partner enzymes. PMID:25110394

  12. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor.

    PubMed

    Wu, Jingjing; Zhang, Mingzhi; Liu, Delong

    2016-01-01

    More and more targeted agents become available for B cell malignancies with increasing precision and potency. The first-in-class Bruton's tyrosine kinase (BTK) inhibitor, ibrutinib, has been in clinical use for the treatment of chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's macroglobulinemia. More selective BTK inhibitors (ACP-196, ONO/GS-4059, BGB-3111, CC-292) are being explored. Acalabrutinib (ACP-196) is a novel irreversible second-generation BTK inhibitor that was shown to be more potent and selective than ibrutinib. This review summarized the preclinical research and clinical data of acalabrutinib. PMID:26957112

  13. 4-H Club Goat Guide.

    ERIC Educational Resources Information Center

    Brown, R. Kipp

    This guide provides information for 4-H Club members who have decided on a club goat project. Topics include general information in the following areas: show rules; facilities and equipment (barns/sheds, fences, feeders, water containers, and equipment); selection (structural correctness, muscle, volume and capacity, style and balance, and growth…

  14. School Book Club Expurgation Practices.

    ERIC Educational Resources Information Center

    Keresey, Gayle

    1984-01-01

    Discusses expurgation practices (deletion, excision, alteration, obliteration of parts of books) of major school book clubs--Scholastic, Xerox's Read Book Club, Troll Associates--as identified by Intellectual Freedom Committee of Young Adult Services Division of the American Library Association. Implications for school libraries are noted.…

  15. The DUDES Club

    PubMed Central

    Gross, Paul A.; Efimoff, Iloradanon; Patrick, Lyana; Josewski, Viviane; Hau, Keith; Lambert, Sandy; Smye, Victoria

    2016-01-01

    Abstract Problem addressed In Canada, there are few health promotion programs for men, particularly programs focused on indigenous and other men marginalized by social and structural inequities. Objective of program To build solidarity and brotherhood among vulnerable men; to promote health through education, dialogue, and health screening clinics; and to help men regain a sense of pride and fulfilment in their lives. Program description The DUDES Club was established in 2010 as a community-based health promotion program for indigenous men in the Downtown Eastside neighbourhood of Vancouver, BC. Between August 2014 and May 2015, 150 men completed an evaluation survey developed using a logic model approach. Responses were analyzed based on the 4 dimensions of the indigenous medicine wheel (mental, physical, emotional, and spiritual). Evaluation results demonstrated high participant satisfaction and positive outcomes across all 4 dimensions of health and well-being: 90.6% of respondents indicated that the DUDES Club program improved their quality of life. Participants who attended meetings more often experienced greater physical, mental, and social benefits (P < .05). Conclusion Findings indicate that this innovative model is effective in promoting the well-being of mainly indigenous men through culturally safe services in an urban community.

  16. A Community-oriented CEOS Atmospheric Composition Portal (ACP)

    NASA Astrophysics Data System (ADS)

    Bernonville, S.; Goussev, O.; Falke, S.; Lindsay, F.; Lynnes, C. S.; Yang, W.; Zhao, P.; Johnson, J.

    2012-04-01

    The Atmospheric Composition Constellation (ACC) and the Workgroup for Information Systems and Services (WGISS) within the Committee on Earth Observation Satellites (CEOS) is developing a portal to support interoperability among the atmospheric composition research and applications communities. The CEOS Atmospheric Composition Portal (ACP) is defining approaches for providing data access, tools and contextual guidance for an international suite of remote sensing datasets. An initial prototype provides access to data services and analysis tools hosted by the World Data Center for Remote Sensing of the Atmosphere (WDC-RSAT), NASA's Goddard Earth Sciences Data and Information Services Center (GES DISC) and DataFed. Distributed access to data is implemented via interoperability standards, including the Open Geospatial Consortium's (OGC) Web Map Service (WMS) and Web Coverage Service (WCS). A fundamental aspect to the design, implementation and evolution of the ACP is community collaboration. The portal is intended as a community resource that is created through collaboration across remotely sensed atmospheric composition data organizations and used by a variety of groups across the climate, air quality, and stratospheric ozone domains. The implementation of interoperability standards in the ACP has involved coordination on identifying the most applicable standards and the definition of community-specific conventions to ensure consistent adoption of standards. This presentation includes an overview of the ACP, its community oriented approach, and use of community-conventions in achieving standards-based interoperability.

  17. Book Clubs. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2010

    2010-01-01

    Book clubs provide a reading framework designed to supplement or organize regular classroom reading instruction for students in grades K-8. This review focuses on "Book Club" (Raphael & McMahon, 1994) and "Literature Circles" (Daniels, 2002), but it uses the general lowercase) term "book clubs" to embrace both "Literature Circles" and "Book Club"…

  18. Computer Club Information Kit for Schools.

    ERIC Educational Resources Information Center

    Association for Educational Data Systems, Washington, DC.

    A computer club can provide a group of high school students with an opportunity to satisfy their curiosity about computers and computer programing. This guide offers suggestions for organizing and running such a club. The objectives of a computer club and the duties of the club's sponsor are outlined. Some activities for the first few meetings are…

  19. Specificities of the Acyl-Acyl Carrier Protein (ACP) Thioesterase and Glycerol-3-Phosphate Acyltransferase for Octadecenoyl-ACP Isomers (Identification of a Petroselinoyl-ACP Thioesterase in Umbelliferae).

    PubMed Central

    Dormann, P.; Frentzen, M.; Ohlrogge, J. B.

    1994-01-01

    This study was designed to address the question: How specific for double bond position and conformation are plant enzymes that act on oleoyl-acyl carrier protein (ACP)? Octadecenoyl-ACPs with cis double bonds at positions [delta]6, [delta]7, [delta]8, [delta]9, [delta]10, [delta]11, or [delta]12 and elaidyl (18:1[delta]9trans)-ACP were synthesized and used to characterize the substrate specificity of the acyl-ACP thioesterase and acyl-ACP:sn-glycerol-3-phosphate acyltransferase. The two enzymes were found to be specific for the [delta]9 position of the double bond. The thioesterase was highly specific for the [delta]9 cis conformation, but the transferase was almost equally active with the cis and the trans isomer of 18:1[delta]9-ACP. In plants such as the Umbelliferae species coriander (Coriandrum sativum L.) that accumulate petroselinic acid (18:1[delta]6cis) in their seed triacylglycerols, a high petroselinoyl-ACP thioesterase activity was found in addition to the oleoyl-ACP thioesterase. The two activities could be separated by anion-exchange chromatography, indicating that the petroselinoyl-ACP thioesterase is represented by a distinct polypeptide. PMID:12232130

  20. Development of markers for Delta9-Stearoyl-ACP-Desaturase (SAD) to screen for cold acclimation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Delta 9-Stearoyl-acyl carrier protein (ACP) desaturase (SAD) is an important enzyme of fatty acid biosynthesis in higher plants. Located in the plastid stroma, SAD catalyzes the desaturation of stearoyl-ACP to oleyl-ACP. SAD plays a key role in determining the ratio of saturated fatty acids to unsat...

  1. Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study

    PubMed Central

    2012-01-01

    Background Modular polyketide synthases are multifunctional megasynthases which biosynthesize a variety of secondary metabolites using various combinations of dehydratase (DH), ketoreductase (KR) and enoyl-reductase (ER) domains. During the catalysis of various reductive steps these domains act on a substrate moiety which is covalently attached to the phosphopantetheine (P-pant) group of the holo-Acyl Carrier Protein (holo-ACP) domain, thus necessitating the formation of holo-ACP:DH and holo-ACP:KR complexes. Even though three dimensional structures are available for DH, KR and ACP domains, no structures are available for DH or KR domains in complex with ACP or substrate moieties. Since Ser of holo-ACP is covalently attached to a large phosphopantetheine group, obtaining complexes involving holo-ACP by standard protein-protein docking has been a difficult task. Results We have modeled the holo-ACP:DH and holo-ACP:KR complexes for identifying specific residues on DH and KR domains which are involved in interaction with ACP, phosphopantetheine and substrate moiety. A novel combination of protein-protein and protein-ligand docking has been used to first model complexes involving apo-ACP and then dock the phosphopantetheine and substrate moieties using covalent connectivity between ACP, phosphopantetheine and substrate moiety as constraints. The holo-ACP:DH and holo-ACP:KR complexes obtained from docking have been further refined by restraint free explicit solvent MD simulations to incorporate effects of ligand and receptor flexibilities. The results from 50 ns MD simulations reveal that substrate enters into a deep tunnel in DH domain while in case of KR domain the substrate binds a shallow surface exposed cavity. Interestingly, in case of DH domain the predicted binding site overlapped with the binding site in the inhibitor bound crystal structure of FabZ, the DH domain from E.Coli FAS. In case of KR domain, the substrate binding site identified by our simulations

  2. Journals Abroad

    ERIC Educational Resources Information Center

    Ando, Shoichi

    1975-01-01

    This article summarizes four journal articles on language teaching appearing in the American pedagogical language journals, "The Modern Language Journal,""English Language Teaching Journal," and "TESOL Quarterly." The purpose is to give an indication of what kinds of articles can be found in journals outside Japan. (Text is in Japanese.) (TL)

  3. Club of Rome

    ScienceCinema

    None

    2011-04-25

    Le Club de Rome s'est fait connaître du grand public par la publication du premier ouvrage "Halte à la croissance" qui a fait l'object d'un débat, il y a 2 ans. Le Prof. Tinbergen a commencé par s'adonner à la physique, il est docteur en physique et très tôt il s'est tourné vers les problèmes sociaux économiques. Il est expert auprès des nombreux gouvernements et organisations internationales et il a vu ses travaux couronnés par le prix Nobel en 1969.

  4. Starting a Planet Protectors Club

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2007

    2007-01-01

    If your mission is to teach children how to reduce, reuse, and recycle waste and create the next generation of Planet Protectors, perhaps leading a Planet Protectors Club is part of your future challenges. You don't have to be an expert in waste reduction and recycling to lead a a Planet Protectors Club. You don't even have to be a teacher. You do…

  5. Developing Preservice Teachers' Knowledge of Science Teaching Through Video Clubs

    NASA Astrophysics Data System (ADS)

    Johnson, Heather J.; Cotterman, Michelle E.

    2015-06-01

    Though an adequate understanding of content is a natural prerequisite of teaching (Carlsen in Journal of Research in Science Teaching 30:471-481, 1993), teachers also need to be able to interpret content in ways that facilitate student learning. How to best support novice teachers in developing and refining their content knowledge for teaching is a crucial and ongoing question for preservice teacher educators. Recently, video clubs are being explored as potential contexts for teacher learning (Barnhart & van Es in Teaching and Teacher Education 45:83-93, 2015; Sherin & Han in Teaching and Teacher Education 20:163-183, 2004). We hypothesized that pairing video clubs with student teaching experiences would provide a forum for preservice teachers to discuss issues relevant to their professional trajectory through exposure to models of peer teaching and opportunities to reflect on practice. In this study, we explored how secondary science preservice teachers used video club to restructure their overall science knowledge into science knowledge for teaching. Our findings suggest that video clubs allowed preservice teachers to access and leverage student thinking and instructional resources to deepen their understanding of science content and trajectories for science learning.

  6. 26 CFR 1.401(m)-2 - ACP test.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... determined under § 1.401(m)-2(b)(2)(iv) (as it appeared in the April 1, 2007, edition of 26 CFR part 1). (E... determined under § 1.401(m)-2(b)(2)(vi) (as it appeared in the April 1, 2007, edition of 26 CFR Part 1). If... 26 Internal Revenue 5 2010-04-01 2010-04-01 false ACP test. 1.401(m)-2 Section 1.401(m)-2...

  7. The Continuous Quality Improvement Book Club: Developing a Book Club to Promote Praxis

    ERIC Educational Resources Information Center

    Lyons, Becky; Ray, Chris

    2014-01-01

    This article poses a model for developing a book club to promote praxis. This model is built upon a basic four step framework for developing book clubs and includes specific recommendations to focus the book club on reflection of theory and how to incorporate it into practice. This model will be used to start a book club examining Continuous…

  8. Clubbing of the fingers or toes

    MedlinePlus

    ... Chronic lung infections that occur in people with bronchiectasis , cystic fibrosis , or lung abscess Infection of the ... Echocardiogram EKG Pulmonary function tests There is no treatment for the clubbing itself. The cause of clubbing ...

  9. Role Calls for Boys & Girls Clubs

    ERIC Educational Resources Information Center

    D'Allesandro, Lou

    2013-01-01

    The New Hampshire Alliance of Boys & Girls Clubs has come a long way since the inception of the state's first Club in Manchester more than 100 years ago. The goal of the Boys & Girls Clubs of America is to provide youth with programs and services that allow them to realize their full potential as productive members of society. State and federal…

  10. Club Sports in Colleges and Universities.

    ERIC Educational Resources Information Center

    Arnold, Jay; And Others

    This report outlines policies to aid administrators of athletic, physical education, and intramural programs as they seek to provide leadership to the club sports movement on their campuses. The report first discusses the recent emergence and popularity of club sports, and explains some advantages of club sports over varsity sports. The next…

  11. How To Be a Great Club Adviser.

    ERIC Educational Resources Information Center

    Granese, Judith

    This guide to being an effective adviser for school clubs begins with an essay explaining the philosophy of school club advisership. It describes the adviser's role as a leader and as a teacher of leadership. Subsequent chapters discuss the following guidelines: (1) club advisers should be aware of the time needed to support and encourage student…

  12. Facilitating a midwifery book club.

    PubMed

    Chenery-Morris, Samantha

    2012-03-01

    A midwifery student book club was set up at University Campus Suffolk (UCS) with the aim of engaging students in alternative forms of literature relevant to their studies and to enhance their university experience. The book club was well attended by first and second year midwifery students, but less so by third years. There was evidence of informal student engagement with the lecturer through follow up emails about the meetings. Most of the books reviewed were enjoyed, but the responsibility of suggesting a book for their peers to review was deemed too much by some students. PMID:22479853

  13. Undergraduate Research in the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    Cates, Ian; Towner, A. P.; Walker-LaFollette, A.; Turner, J.; Hardegree-Ullman, K.; Pearson, K.

    2014-01-01

    Participation in research as an undergraduate is an invaluable learning experience that leads to successful post-undergrad studies. Because of this, the University of Arizona Astronomy Club strives to provide multiple opportunities for its members to get involved in research as early as possible. Areas of research covered by our projects include exoplanet research, stellar cycles, and radio observations. These projects cover exoplanet parameterization, the utilization of Kepler data, and various star-formation studies, respectively. Participation in our projects builds stronger data-collecting and reduction skills, while also leading to tangible achievements such poster presentations at AAS, ASP, and DPS, and published papers in astronomical journals.

  14. A Science Club Takes Action

    ERIC Educational Resources Information Center

    LeDee, Olivia; Mosser, Anna; Gamble, Tony; Childs, Greg; Oberhauser, Karen

    2007-01-01

    The after-school science club at Galtier Math, Science, and Technology Elementary Magnet School in St. Paul, Minnesota, learned some valuable lessons when they took newfound knowledge about pollution into their homes. After learning about the effects of various contaminants on health and what informed citizens can do about it, students tested…

  15. Club Drugs. The DAWN Report.

    ERIC Educational Resources Information Center

    Substance Abuse and Mental Health Services Administration (DHHS/PHS), Rockville, MD. Office of Applied Studies.

    This report was prepared in response to requests from the media, law enforcement, and community leaders for information about club drugs. By being able to utilize statistics from hospital emergency departments and by compiling statistics on drug-related deaths, the Drug Abuse Warning Network (DAWN) is able to alert parents, educators, and others…

  16. Science Club--A Concept

    ERIC Educational Resources Information Center

    Wegner, Claas; Issak, Nicole; Tesch, Katharina; Zehne, Carolin

    2016-01-01

    The following article presents a concept of a science club which was developed by two master's students as a part of their thesis and which has been developed and improved ever since. The extra-curricular concept emphasises pupils' individuality through focusing on problem based leaning, station learning, and mixed age groups. Having joined the…

  17. Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity

    PubMed Central

    2011-01-01

    Background Acyl-acyl carrier protein thioesterases (acyl-ACP TEs) catalyze the hydrolysis of the thioester bond that links the acyl chain to the sulfhydryl group of the phosphopantetheine prosthetic group of ACP. This reaction terminates acyl chain elongation of fatty acid biosynthesis, and in plant seeds it is the biochemical determinant of the fatty acid compositions of storage lipids. Results To explore acyl-ACP TE diversity and to identify novel acyl ACP-TEs, 31 acyl-ACP TEs from wide-ranging phylogenetic sources were characterized to ascertain their in vivo activities and substrate specificities. These acyl-ACP TEs were chosen by two different approaches: 1) 24 TEs were selected from public databases on the basis of phylogenetic analysis and fatty acid profile knowledge of their source organisms; and 2) seven TEs were molecularly cloned from oil palm (Elaeis guineensis), coconut (Cocos nucifera) and Cuphea viscosissima, organisms that produce medium-chain and short-chain fatty acids in their seeds. The in vivo substrate specificities of the acyl-ACP TEs were determined in E. coli. Based on their specificities, these enzymes were clustered into three classes: 1) Class I acyl-ACP TEs act primarily on 14- and 16-carbon acyl-ACP substrates; 2) Class II acyl-ACP TEs have broad substrate specificities, with major activities toward 8- and 14-carbon acyl-ACP substrates; and 3) Class III acyl-ACP TEs act predominantly on 8-carbon acyl-ACPs. Several novel acyl-ACP TEs act on short-chain and unsaturated acyl-ACP or 3-ketoacyl-ACP substrates, indicating the diversity of enzymatic specificity in this enzyme family. Conclusion These acyl-ACP TEs can potentially be used to diversify the fatty acid biosynthesis pathway to produce novel fatty acids. PMID:21831316

  18. Walking Together: A Narrative/Pastoral Approach to the ACPE Accreditation Site Visit

    ERIC Educational Resources Information Center

    Oertli, Karrie

    2010-01-01

    Walking together is a strong theme in religious literature: God companions persons, and persons companion one another. All share and hear stories in that action. The Association for Clinical Pastoral Education, Inc. (ACPE) began to walk together in 1967, as it gathered four organizations into one. ACPE has grown and changed, becoming world's…

  19. The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

    PubMed Central

    Van Vranken, Jonathan G; Jeong, Mi-Young; Wei, Peng; Chen, Yu-Chan; Gygi, Steven P; Winge, Dennis R; Rutter, Jared

    2016-01-01

    Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily conserved role in FeS biogenesis. ACP is a stable and essential subunit of the eukaryotic FeS biogenesis complex. In the absence of ACP, the complex is destabilized resulting in a profound depletion of FeS throughout the cell. This role of ACP depends upon its covalently bound 4’-phosphopantetheine (4-PP)-conjugated acyl chain to support maximal cysteine desulfurase activity. Thus, it is likely that ACP is not simply an obligate subunit but also exploits the 4-PP-conjugated acyl chain to coordinate mitochondrial fatty acid and FeS biogenesis. DOI: http://dx.doi.org/10.7554/eLife.17828.001 PMID:27540631

  20. The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis.

    PubMed

    Van Vranken, Jonathan G; Jeong, Mi-Young; Wei, Peng; Chen, Yu-Chan; Gygi, Steven P; Winge, Dennis R; Rutter, Jared

    2016-01-01

    Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily conserved role in FeS biogenesis. ACP is a stable and essential subunit of the eukaryotic FeS biogenesis complex. In the absence of ACP, the complex is destabilized resulting in a profound depletion of FeS throughout the cell. This role of ACP depends upon its covalently bound 4'-phosphopantetheine (4-PP)-conjugated acyl chain to support maximal cysteine desulfurase activity. Thus, it is likely that ACP is not simply an obligate subunit but also exploits the 4-PP-conjugated acyl chain to coordinate mitochondrial fatty acid and FeS biogenesis. PMID:27540631

  1. Boys and Girls: Join the Club

    ERIC Educational Resources Information Center

    D'Allesandro, Lou; Wool, Michael; McKenzie, Mary Alice

    2012-01-01

    Boys & Girls Clubs of America count 4,000 community-based clubs serving more than 4 million young people through membership and community outreach. They provide a safe place to spend time during non-school hours and the summer as an alternative to the streets or being home alone--a place to play, have fun and learn. Boys & Girls Clubs began in New…

  2. View of yacht club and avila pier, facing west. The ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of yacht club and avila pier, facing west. The San Luis Bay Club is visible on the hill in the background. - San Luis Yacht Club, Avila Pier, South of Front Street, Avila Beach, San Luis Obispo County, CA

  3. Journalism Forum.

    ERIC Educational Resources Information Center

    Reddick, David B.; Lehnert, Eileen; And Others

    1980-01-01

    Contains five short discussions on the following topics: (1) using precision journalism techniques, (2) coping with teacher evaluation, (3) a program in which journalism students help produce a Sunday newspaper edition, (4) a course in international mass communications, and (5) professional journalists' opinions of the content of master's…

  4. New Journalism.

    ERIC Educational Resources Information Center

    Fishwick, Marshall, Ed.

    This volume contains a selection of articles which examine, critique, and help to define the phenomenon of new journalism. Included are "Popular Culture and the New Journalism" (Marshall Fishwick), "Entrance" (Richard A. Kallan), "How 'New'?" (George A. Hough III), "Journalistic Primitivism" (Everette E. Dennis), "Wherein Lies the Value?" (Michael…

  5. HRD Journals.

    ERIC Educational Resources Information Center

    1996

    This document consists of four papers presented during a symposium on human resource development (HRD) journals moderated by Peter W.J. Schramade at the 1996 conference of the Academy of Human Resource Development. "Refereed Journals: The Cornerstone of a Developing Profession" (Gary N. McLean) describes the purpose, format, success, and…

  6. Club Drug Use in Hispanic College Students

    PubMed Central

    Resor, Michelle R.; Cooper, Theodore V.

    2010-01-01

    Club drug use and correlates were examined among 251 Hispanic college students on the Texas - México border. Participants completed questionnaires on substance use, club drug attitudes and beliefs, sexual risk-taking behaviors, depressive symptoms, and acculturation. One-quarter of participants reported club drug use. Regression analyses demonstrated that frequency and history of lifetime use were consistently associated with more permissive drug attitudes and other substance use but not sexual risk-taking, depression symptoms, or acculturation. Acculturation was negatively associated with frequency of club drug use, yet positively associated with use of other illicit substances. Avenues for future studies are suggested. PMID:20653638

  7. Healthy Living Initiative: Running/Walking Club

    ERIC Educational Resources Information Center

    Stylianou, Michalis; Kulinna, Pamela Hodges; Kloeppel, Tiffany

    2014-01-01

    This study was grounded in the public health literature and the call for schools to serve as physical activity intervention sites. Its purpose was twofold: (a) to examine the daily distance covered by students in a before-school running/walking club throughout 1 school year and (b) to gain insights on the teachers perspectives of the club.…

  8. Book Clubs Turn the Page to Learning

    ERIC Educational Resources Information Center

    Sennett, Frank

    2006-01-01

    The nation's schools and libraries have come up with shelves full of innovative twists on the basic book club. This article offers a few of these fun and educational ideas that can be adapted for everyone from young beginning readers to teens. Teachers and librarians describe book club activities that they have found successful in: bringing…

  9. Running Clubs--A Combinatorial Investigation.

    ERIC Educational Resources Information Center

    Nissen, Phillip; Taylor, John

    1991-01-01

    Presented is a combinatorial problem based on the Hash House Harriers rule which states that the route of the run should not have previously been traversed by the club. Discovered is how many weeks the club can meet before the rule has to be broken. (KR)

  10. What A Booster Club Can Do.

    ERIC Educational Resources Information Center

    Hidinger, George

    This speech was presented at the 1976 American Alliance for Health, Physical Education, and Recreation national convention by the principal of an Iowa high school. It discusses the development and effectiveness of the Jefferson High School Booster Club which was developed by an interested parent and has been quite successful. The club has assisted…

  11. STEM Club Participation and STEM Schooling Outcomes

    ERIC Educational Resources Information Center

    Gottfried, Michael A.; Williams, Darryl N.

    2013-01-01

    To develop a more robust understanding of the relationship between non-formal, school-based STEM activities and students' success and persistence in STEM fields, this study evaluates how math club participation influences math GPA and how science club participation influences science GPA. Additionally, this study evaluates how math or science…

  12. Multicultural Mosaic: A Family Book Club.

    ERIC Educational Resources Information Center

    Dias-Mitchell, Laurie; Harris, Elizabeth

    2001-01-01

    Authors, a library media specialist and a literature/language arts teacher, both recipients of Theodore R. Sizer Fellowships, describe their joint project, "Multicultural Mosaic: A Family Book Club." Their proposal was to strengthen the home-school connection by establishing a book club accessible to all middle and high school students and their…

  13. A Different Kind of Book Club.

    ERIC Educational Resources Information Center

    Lesperance, Gerald

    2002-01-01

    Describes one teacher's experiences developing a book group for students in his suburban New York high school. Rather than attending required meetings, students read any book they chose and submitted book reviews on a book club bulletin board. For each book completed, students received a free book and eligibility to attend book club sponsored…

  14. Partners against tuberculosis: Ethiopia's "TB clubs".

    PubMed

    Getahun, H

    1998-11-01

    TB (tuberculosis) clubs were first introduced in the Estie district of South Gonder administrative zone, Amhara region of northwestern Ethiopia in January 1997, in an attempt to improve TB control in rural areas. Before the clubs were introduced, patients who were family members or close neighbors were given different treatment follow-up dates. Walking long distances alone to secure treatment, patients often grew discouraged from continuing treatment once their health began to improve. However, upon the introduction of the TB clubs, neighboring patients, or those in the same family, had their follow-up appointment dates rearranged in the same clinics. Local neighborhoods were also used to group nearby patients in the same follow-up clinic. The patients then formed their own groups (TB clubs) and elected leaders. 3-10 members usually comprise each club, with the club leaders monitoring drug intake and new developments, such as drug side effects and toxic skin reactions. The social ostracism and stigma otherwise experienced by patients have been largely overcome as a result of the TB information disseminated within the communities by the clubs, while patient attendance for treatment has increased from 68% to 98%, according to one study's findings. This intervention has taken place using the long-course treatment protocol (2STH/EH and 10TH/EH). TB clubs are improving patient adherence to treatment, passive case detection, defaulter tracing, TB reporting and recording, and community involvement in health care. PMID:12294916

  15. STEM Club Participation and STEM Schooling Outcomes

    ERIC Educational Resources Information Center

    Gottfried, Michael A.; Williams, Darryl N.

    2013-01-01

    To develop a more robust understanding of the relationship between non-formal, school-based STEM activities and students' success and persistence in STEM fields, this study evaluates how math club participation influences math GPA and how science club participation influences science GPA. Additionally, this study evaluates how math or science club…

  16. Practices of Productive Adult Book Clubs

    ERIC Educational Resources Information Center

    Beach, Richard; Yussen, Steven

    2011-01-01

    Abstract: This article examines two adult book club members' responses to literary texts over a 23-month period to identify practices that contribute to productive book club participation. Members were interviewed regarding their book selection procedures, preparation for and perceptions of the discussions, and what they valued about the…

  17. Expression and specificity profile of the major acetate transporter AcpA in Aspergillus nidulans.

    PubMed

    Sá-Pessoa, Joana; Amillis, Sotiris; Casal, Margarida; Diallinas, George

    2015-03-01

    AcpA has been previously characterized as a high-affinity transporter essential for the uptake and use of acetate as sole carbon source in Aspergillus nidulans. Here, we follow the expression profile of AcpA and define its substrate specificity. AcpA-mediated acetate transport is detected from the onset of conidiospore germination, peaks at the time of germ tube emergence, and drops to low basal levels in germlings and young mycelia, where a second acetate transporter is also becoming apparent. AcpA activity also responds to acetate presence in the growth medium, but is not subject to either carbon or nitrogen catabolite repression. Short-chain monocarboxylates (benzoate, formate, butyrate and propionate) inhibit AcpA-mediated acetate transport with apparent inhibition constants (Ki) of 16.89±2.12, 9.25±1.01, 12.06±3.29 and 1.44±0.13mM, respectively. AcpA is also shown not to be directly involved in ammonia export, as proposed for its Saccharomyces cerevisiae homologue Ady2p. In the second part of this work, we search for the unknown acetate transporter expressed in mycelia, and for other transporters that might contribute to acetate uptake. In silico analysis, genetic construction of relevant null mutants, and uptake assays, reveal that the closest AcpA homologue (AN1839), named AcpB, is the 'missing' secondary acetate transporter in mycelia. We also identify two major short-chain carboxylate (lactate, succinate, pyruvate and malate) transporters, named JenA (AN6095) and JenB (AN6703), which however are not involved in acetate uptake. This work establishes a framework for further exploiting acetate and carboxylate transport in filamentous ascomycetes. PMID:25708319

  18. Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases.

    PubMed

    Zhang, Xiujun; Li, Mai; Agrawal, Arpita; San, Ka-Yiu

    2011-11-01

    Microbial biosynthesis of fatty acid-like chemicals from renewable carbon sources has attracted significant attention in recent years. Free fatty acids can be used as precursors for the production of fuels or chemicals. Free fatty acids can be produced by introducing an acyl-acyl carrier protein thioesterase gene into Escherichia coli. The presence of the acyl-ACP thioesterase will break the fatty acid elongation cycle and release free fatty acid. Depending on their sequence similarity and substrate specificity, class FatA thioesterase is active on unsaturated acyl-ACPs and class FatB prefers saturated acyl group. Different acyl-ACP thioesterases have different degrees of chain length specificity. Although some of these enzymes have been characterized from a number of sources, information on their ability to produce free fatty acid in microbial cells has not been extensively examined until recently. In this study, we examined the effect of the overexpression of acyl-ACP thioesterase genes from Diploknema butyracea, Gossypium hirsutum, Ricinus communis and Jatropha curcas on free fatty acid production. In particular, we are interested in studying the effect of different acyl-ACP thioesterase on the quantities and compositions of free fatty acid produced by an E. coli strain ML103 carrying these constructs. It is shown that the accumulation of free fatty acid depends on the acyl-ACP thioesterase used. The strain carrying the acyl-ACP thioesterase gene from D. butyracea produced approximately 0.2g/L of free fatty acid while the strains carrying the acyl-ACP thioesterase genes from R. communis and J. curcas produced the most free fatty acid at a high level of more than 2.0 g/L at 48 h. These two strains accumulated three major straight chain free fatty acids, C14, C16:1 and C16 at levels about 40%, 35% and 20%, respectively. PMID:22001432

  19. The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal.

    PubMed

    Cronan, John E

    2014-06-01

    ACPs (acyl carrier proteins) play essential roles in the synthesis of fatty acids, polyketides and non-ribosomal polypeptides. ACP function requires the modification of the protein by attachment of 4'-phosphopantetheine to a conserved serine residue. The phosphopantetheine thiol acts to tether the starting materials and intermediates as their thioesters. ACPs are small highly soluble proteins composed of four α-helices. The helices form a bundle that acts as a hydrophobic sleeve that sequesters the acyl chains and activated thioesters from solvent. However, in the synthesis of fatty acids and complex lipids the enzymes of the pathway must access the thioester and the proximal carbon atoms in order to perform the needed chemistry. How such access is provided without exposure of the acyl chains to solvent has been a longstanding question due to the lack of acyl-ACP-enzyme complexes, a situation generally attributed to the brevity of the interactions of acyl-ACPs with their cognate enzymes. As discussed in the present review the access question has now been answered by four recent crystal structures, each of which shows that the entire acyl chain plus the 4'-phosphopantetheine prosthetic group partitions from the ACP hydrophobic sleeve into a hydrophobic pocket or groove of the enzyme protein, a process termed chain flipping. PMID:24825445

  20. DEVELOPMENT OF A HOMEMAKER'S CLUB, LARIMER COUNTY, FORT COLLINS, COLORADO.

    ERIC Educational Resources Information Center

    EDGINGTON, ROYAL H.

    THE ORGANIZATION OF A HOMEMAKER'S CLUB FOR MOTHERS UNDER AID TO DEPENDENT CHILDREN WAS PRESENTED. THE CLUB WAS SPONSORED BY THE LARIMER COUNTY DEPARTMENT OF PUBLIC WELFARE. PERSONNEL FROM THE DEPARTMENT ASSISTED IN EVALUATING A PAST FAILURE OF A HOMEMAKER'S CLUB AND IN FORMULATING PLANS FOR A SECOND CLUB. A DISCUSSION OF THE FAILURE OF THE FIRST…

  1. The Sierra Club--A History. Part 2: Conservation

    ERIC Educational Resources Information Center

    Strong, Douglas H.

    1977-01-01

    This second article on Sierra Club history brings the Club into the 1960s. It relates early conservation activities of the club, such as the efforts to save the Hetch Hetchy Valley. The campaign against construction of a dam in Dinosaur National Monument helped establish the club as a national organization. (MA)

  2. Biomedical journals: keeping up and reading critically.

    PubMed

    Chase, Karen L; DiGiacomo, Ronald F; Van Hoosier, Gerald L

    2006-09-01

    By extrapolation from studies of physicians, knowledge and practice of laboratory animal medicine and science are expected to become progressively more outdated the longer practitioners are out of school. Keeping up with current literature and practice is a challenge that necessitates the use of many different sources of continuing education. Both veterinarians and physicians consistently list journals as the most beneficial source of new information. Accordingly, they must select from the veterinary and biomedical literature articles that report original studies and systematic reviews and recognize and respond to valid new knowledge to improve diagnostic and therapeutic approaches and maintain consistent clinical skills. Other objectives include selecting journals for general information and for information relevant or specific to one's field of research. Lastly, candidates for board certification need to read articles from journals that potentially provide the basis for questions on the examination. 'High-impact' journals should be identified, and articles should be reviewed critically. In a survey of recent candidates for laboratory animal medicine board examination, these journals included Contemporary Topics (now JAALAS), Comparative Medicine, ILAR Journal, and Laboratory Animals. Strategies for coping with the challenge of staying current with the literature include wise use of technology, journal clubs, and consultation with colleagues. A laboratory animal practitioner can become a better scientist and clinician by evaluating the research performed by others. Thorough, critical review of biomedical literature is paramount to these goals. PMID:16995641

  3. Characterization of soluble acyl-ACP desaturases from Camelina sativa, Macadamia tetraphylla and Dolichandra unguis-cati.

    PubMed

    Rodríguez, Manuel Fernando Rodríguez; Sánchez-García, Alicia; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2015-04-15

    Acyl-acyl carrier protein (ACP) desaturases (EC 1.14.19.2) are soluble enzymes that catalyse the insertion of a double bond into saturated fatty acid bound in saturated acyl chains bound to ACP in higher plants, producing cis-monounsaturated fatty acids. Three types of soluble acyl-ACP desaturases have been described: Δ(9)-acyl-ACP, Δ(6)-acyl-ACP and Δ(4)-acyl-ACP desaturases, which differ in the substrate specificity and the position in which the double bond is introduced. In the present work, Camelina sativa (CsSAD), Macadamia tetraphylla (MtSAD) and Dolichandra unguis-cati (DuSAD) desaturases were cloned, sequenced and characterized. Single copies of CsSAD, MtSAD and DuSAD with three, one and two different alleles, respectively, were found. The corresponding mature proteins were heterologously expressed in Escherichia coli for biochemical characterization in protein extracts. The recombinant CsSAD enzyme showed 300-fold higher specificity towards 18:0-ACP than 16:0-ACP. Similar profile exhibited MtSAD although the differences in the specificity were lower, around 170-fold higher for 18:0-ACP than 16:0-ACP. Furthermore, DuSAD presented a profile showing preference towards 16:0-ACP against 18:0-ACP, around twice more, being so a Δ(9) palmitoyl-ACP desaturase. Also, we reported the expression profile of CsSAD, which showed the highest levels of expression in expanding tissues that typically are very active in lipid biosynthesis such as developing seed endosperm. Moreover, the possibility to express a new desaturase in C. sativa (oilseed crop that store high levels of oil and is easy to transform) to create a new line rich in short monounsaturated fatty acid is discussed. PMID:25765361

  4. How to Make a Club from Scratch: The Beginning of the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    Robertson, Amy; Hardegree-Ullman, K.; Towner, A. P.; Walker-LaFollette, A.; Carleton, T.; McCarthy, D. W.

    2014-01-01

    Beginning and maintaining an independent, student run club can be a challenge. The University of Arizona Astronomy Club has been working hard to build a strong basis since its revitalization in 2007. Since that time, the club has evolved and learned strategies for increasing and maintaining membership through research, community outreach, fund raising, telescope building projects and educational scale models. We will discuss how club involvement benefits astronomy and non-astronomy majors, the University, the astronomical community and the local community through social support and networking.

  5. Journalism Forum

    ERIC Educational Resources Information Center

    Journalism Educator, 1985

    1985-01-01

    Includes (1) survey results indicating value of traditional journalism and mass communication research; (2) survey results indicating knowledge of grammar, economics, and government are journalists' most valuable resources; (3) methods for teaching listening skills; (4) suggestions for giving public relations students an overview online services;…

  6. Ecosystem Journalism

    ERIC Educational Resources Information Center

    Robertson, Amy; Mahlin, Kathryn

    2005-01-01

    If the organisms in a prairie ecosystem created a newspaper, what would it look like? What important news topics of the ecosystem would the organisms want to discuss? Imaginative and enthusiastic third-grade students were busy pondering these questions as they tried their hands at "ecosystem journalism." The class had recently completed a study of…

  7. Journal Production and Journal Impact Factors.

    ERIC Educational Resources Information Center

    Rousseau, Ronald; Van Hooydonk, Guido

    1996-01-01

    Describes a direct linear relation between the number of articles in a journal and the journal's impact factor. Hypotheses are presented; theoretical considerations are discussed; and results are described that show exceptions for review journals and translation journals, as well as for journals in mathematics and chemistry. (Author/LRW)

  8. Interaction between infectious diseases and personality traits: ACP1*C as a potential mediator.

    PubMed

    Napolioni, Valerio; Murray, Damian R; Comings, David E; Peters, Warren R; Gade-Andavolu, Radhika; MacMurray, James

    2014-08-01

    In geographical regions characterized by high pathogen prevalence, it has been shown that human populations tend to be characterized by lower levels of extraversion (E) and openness to experience (OtE). According to the "behavioral immune system" hypothesis, the reduction of extraversion and openness levels represents a behavioral defense against infections. Like the 'classical' immune system, the "behavioral immune system" could also be shaped by its underlying genetic background. Previous studies have shown that the *C allele of the ACP1 gene confers increased susceptibility to infectious/parasitic diseases. We hypothesized that carriers of the ACP1*C allele should likewise be associated with reduced E and OtE. We tested this hypothesis using two samples comprised of 153 students from Southern California (Group 1), and 162 female subjects recruited from an executive health program (Group 2), genotyped for ACP1 polymorphism and evaluated by the NEO Five-Factor Inventory (NEO-FFI). ACP1 was significantly associated with E: we found that carriers of ACP1*C showed reduced scores for E (Group 1: β=-4.263, P=0.027; Group 2: β=-8.315, P=0.003; Group 1+Group 2: β=-5.366, P=0.001). Across groups, ACP1 was only marginally associated with OtE. In conclusion, the present study found that the ACP1*C allele, previously associated with an increased vulnerability to infectious/parasitic diseases may also be able to shape behavioral immune defenses by interaction with the level of E. PMID:24933463

  9. The Outing Club: Science without Walls

    ERIC Educational Resources Information Center

    Dawson, Paul Dow; Burks, Timothy

    1975-01-01

    In an attempt to give students an opportunity to strengthen skills that will make them effective group members, authors developed a program, "The Doherty School Outing Club", that stresses group dynamics in an outdoor setting. (Author/RK)

  10. Florida, National Space Club Embrace Commercial Endeavors

    NASA Video Gallery

    NASA's Commercial Crew Program (CCP) Manager Ed Mango and Florida's Lt. Gov. Jennifer Carroll were guest speakers at the National Space Club Florida Committee's luncheon at the Radisson Resort at t...

  11. Hong Kong: women's club movement expanding.

    PubMed

    1980-01-01

    2 more women's clubs have been opened by the Family Planning Association of Hong Kong following the success of the 1st such club at Yue Taipo organized in September 1970. The 2nd club is located at the Hing Shing Temporary Housing Area in Kwai Chung and caters to new residents. The 3rd, established January 4, 1980, is located at the Fortune Street Temporary Housing Area in Cheung Sha Wan. The overall aim of these clubs is to give a boost to the quality of family life through organized educational and recreational facilities. Activities at both clubs were initiated by formal opening ceremonies presided over by representatives of the Housing Estates and Family Planning Association. Welcoming wellwishers at each ceremony, Mrs. Peggy Lam, Acting Director of the Family Planning Association of Hong Kong; drew attention to the important contribution made by family planning to the well being of families. It was through the wise planning of their families that parents were provided with ample time and energy for the upbringing of chilren, said Mrs. Lam. The activities of the women's clubs include instruction on traditional women's activities, and talks on sanitation, childrearing, interpersonal relations, nutrition, and permanent contraception. Mrs. Lam felt that the fact that 79% of married women of childbearing age in Hing Shing were practicing family planning was most encouraging. PMID:12262028

  12. Effect of CPP/ACP on initial bioadhesion to enamel and dentin in situ.

    PubMed

    Grychtol, Susann; Basche, Sabine; Hannig, Matthias; Hannig, Christian

    2014-01-01

    The present in situ study investigated the influence of a preparation containing CPP/ACP (caseinphosphopeptide-amorphous calcium phosphate) (GC Tooth mousse) on initial bacterial colonization of enamel and dentin. Therefore, pellicle formation was performed in situ on bovine enamel and dentin specimens fixed to individual upper jaw splints worn by 8 subjects. After 1 min of pellicle formation GC Tooth mousse was used according to manufacturer's recommendations. Rinses with chlorhexidine served as positive controls. Specimens carried without any rinse served as negative controls. After 8 h overnight exposure of the splints, bacterial colonization was quantified by fluorescence microscopy (DAPI and BacLight live/dead staining). Additionally, the colony forming units (CFU) were determined after desorption. Furthermore, the effects on Streptococcus mutans bacteria were tested in vitro (BacLight). There was no significant impact of CPP/ACP on initial bacterial colonization proved with DAPI and BacLight. Determination of CFU showed statistical significance for CPP/ACP to reduce bacterial adherence on enamel. The in vitro investigation indicated no antimicrobial effects for CPP/ACP on Streptococcus mutans suspension. Under the chosen conditions, CPP/ACP (GC Tooth mousse) had no significant impact on initial biofilm formation on dental hard tissues. The tested preparation cannot be recommended for biofilm management. PMID:25386603

  13. Effect of CPP/ACP on Initial Bioadhesion to Enamel and Dentin In Situ

    PubMed Central

    2014-01-01

    The present in situ study investigated the influence of a preparation containing CPP/ACP (caseinphosphopeptide-amorphous calcium phosphate) (GC Tooth mousse) on initial bacterial colonization of enamel and dentin. Therefore, pellicle formation was performed in situ on bovine enamel and dentin specimens fixed to individual upper jaw splints worn by 8 subjects. After 1 min of pellicle formation GC Tooth mousse was used according to manufacturer's recommendations. Rinses with chlorhexidine served as positive controls. Specimens carried without any rinse served as negative controls. After 8 h overnight exposure of the splints, bacterial colonization was quantified by fluorescence microscopy (DAPI and BacLight live/dead staining). Additionally, the colony forming units (CFU) were determined after desorption. Furthermore, the effects on Streptococcus mutans bacteria were tested in vitro (BacLight). There was no significant impact of CPP/ACP on initial bacterial colonization proved with DAPI and BacLight. Determination of CFU showed statistical significance for CPP/ACP to reduce bacterial adherence on enamel. The in vitro investigation indicated no antimicrobial effects for CPP/ACP on Streptococcus mutans suspension. Under the chosen conditions, CPP/ACP (GC Tooth mousse) had no significant impact on initial biofilm formation on dental hard tissues. The tested preparation cannot be recommended for biofilm management. PMID:25386603

  14. Efficacious long-term cooling and freezing of Sapajus apella semen in ACP-118(®).

    PubMed

    Leão, D L; Miranda, S A; Brito, A B; Lima, J S; Santos, R R; Domingues, S F S

    2015-08-01

    The objectives of the present study were to test the effect of coconut water solution (CWS), TES-TRIS and ACP-118(®) on the seminal cooling and cryopreservation of semen from capuchin monkeys (Sapajus apella). Semen was collected from six males by electro-ejaculation, diluted in TES-TRIS, CWS or ACP-118(®), and maintained at 4°C for 28h. Semen was subsequently evaluated (Experiment I) or cryopreserved in the presence of different glycerol concentrations (3%, 5% or 7%) (Experiment II). ACP-118(®) was the preferred extender to preserve sperm motility and viability after 28h incubation at 4°C. Cooled sperm were successfully frozen-thawed in a medium containing 3% glycerol. After thawing, sperm retained the capacity to fertilize oocytes and zygotes were obtained. In conclusion, ACP-118(®) can be effectively and efficiently used as extender for the cooling of S. apella semen. Furthermore, cryopreservation using ACP-118(®) by adding 3% glycerol is suitable to maintain sperm morphology and the capacity of these cells to fertilize in vitro. PMID:26071650

  15. iACP: a sequence-based tool for identifying anticancer peptides

    PubMed Central

    Chen, Wei; Ding, Hui; Feng, Pengmian; Lin, Hao; Chou, Kuo-Chen

    2016-01-01

    Cancer remains a major killer worldwide. Traditional methods of cancer treatment are expensive and have some deleterious side effects on normal cells. Fortunately, the discovery of anticancer peptides (ACPs) has paved a new way for cancer treatment. With the explosive growth of peptide sequences generated in the post genomic age, it is highly desired to develop computational methods for rapidly and effectively identifying ACPs, so as to speed up their application in treating cancer. Here we report a sequence-based predictor called iACP developed by the approach of optimizing the g-gap dipeptide components. It was demonstrated by rigorous cross-validations that the new predictor remarkably outperformed the existing predictors for the same purpose in both overall accuracy and stability. For the convenience of most experimental scientists, a publicly accessible web-server for iACP has been established at http://lin.uestc.edu.cn/server/iACP, by which users can easily obtain their desired results. PMID:26942877

  16. [Constructing an ACP Simulation-Situation Communication Training Program for Patients With Chronic Kidney Disease].

    PubMed

    Chen, Jui-O; Lin, Chiu-Chu

    2016-06-01

    The aging population and changing lifestyles have lead to the increased general risk of chronic kidney disease. Taiwan currently has the highest incidence and prevalence of end-stage renal disease (ESRD) of any country or region in the world. Hemodialysis patients must endure comorbidities and face the uncertainties of death. The best way to achieve a good death is for patients to sign advance care planning (ACP). However, the key factors contributing to low ACP signature rates have been the lack of communication skills and related training among medical staffs. This article explores the dilemma of ACP using an example of chronic kidney disease (CKD) and proposes a theory-based approach to develop a theoretical framework for an ACP simulation-situation communication training program that integrates the simulation situation model, PREPARED model, and scaffolding theory. Readers may use this framework to design ACP simulation-situation communication training programs that conform to their own conditions and then test the effectiveness and feasibility of these programs in clinical settings. PMID:27250964

  17. 76 FR 27253 - Safety Zone; Catawba Island Club Fireworks, Catawba Island Club, Port Clinton, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Catawba Island Club Fireworks, Catawba Island Club, Port Clinton, OH AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast... Clinton, Ohio. This zone is intended to restrict vessels from portions of Lake Erie for the Catawba...

  18. Advanced spent fuel conditioning process (ACP) progress with respect to remote operation and maintenance

    SciTech Connect

    Lee, Hyo Jik; Lee, Jong Kwang; Park, Byung Suk; Yoon, Ji Sup

    2007-07-01

    Korea Atomic Energy Research Institute (KAERI) has been developing an Advanced Spent Fuel Conditioning Process (ACP) to reduce the volume of spent fuel, and the construction of the ACP facility (ACPF) for a demonstration of its technical feasibility has been completed. In 2006 two inactive demonstrations were performed with simulated fuels in the ACPF. Accompanied by process equipment performance tests, its remote operability and maintainability were also tested during that time. Procedures for remote operation tasks are well addressed in this study and evaluated thoroughly. Also, remote maintenance and repair tasks are addressed regarding some important modules with a high priority order. The above remote handling test's results provided a lot of information such as items to be revised to improve the efficiency of the remote handling tasks. This paper deals with the current status of ACP and the progress of remote handling of ACPF. (authors)

  19. Acyl-ACP Substrate Recognition in Burkholderia mallei BmaI1 Acyl-Homoserine Lactone Synthase

    PubMed Central

    2015-01-01

    The acyl-homoserine lactone (AHL) autoinducer mediated quorum sensing regulates virulence in several pathogenic bacteria. The hallmark of an efficient quorum sensing system relies on the tight specificity in the signal generated by each bacterium. Since AHL signal specificity is derived from the acyl-chain of the acyl-ACP (ACP = acyl carrier protein) substrate, AHL synthase enzymes must recognize and react with the native acyl-ACP with high catalytic efficiency while keeping reaction rates with non-native acyl-ACPs low. The mechanism of acyl-ACP substrate recognition in these enzymes, however, remains elusive. In this study, we investigated differences in catalytic efficiencies for shorter and longer chain acyl-ACP substrates reacting with an octanoyl-homoserine lactone synthase Burkholderia mallei BmaI1. With the exception of two-carbon shorter hexanoyl-ACP, the catalytic efficiencies of butyryl-ACP, decanoyl-ACP, and octanoyl-CoA reacting with BmaI1 decreased by greater than 20-fold compared to the native octanoyl-ACP substrate. Furthermore, we also noticed kinetic cooperativity when BmaI1 reacted with non-native acyl-donor substrates. Our kinetic data suggest that non-native acyl-ACP substrates are unable to form a stable and productive BmaI1·acyl-ACP·SAM ternary complex and are thus effectively discriminated by the enzyme. These results offer insights into the molecular basis of substrate recognition for the BmaI1 enzyme. PMID:25215658

  20. Stacking of a stearoyl-ACP thioesterase with a dual-silenced palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase in transgenic soybean.

    PubMed

    Park, Hyunwoo; Graef, George; Xu, Yixiang; Tenopir, Patrick; Clemente, Tom E

    2014-10-01

    Soybean (Glycine max (L.) Merr) is valued for both its protein and oil, whose seed is composed of 40% and 20% of each component, respectively. Given its high percentage of polyunsaturated fatty acids, linoleic acid and linolenic acid, soybean oil oxidative stability is relatively poor. Historically food processors have employed a partial hydrogenation process to soybean oil as a means to improve both the oxidative stability and functionality in end-use applications. However, the hydrogenation process leads to the formation of trans-fats, which are associated with negative cardiovascular health. As a means to circumvent the need for the hydrogenation process, genetic approaches are being pursued to improve oil quality in oilseeds. In this regard, we report here on the introduction of the mangosteen (Garcinia mangostana) stearoyl-ACP thioesterase into soybean and the subsequent stacking with an event that is dual-silenced in palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase expression in a seed-specific fashion. Phenotypic analyses on transgenic soybean expressing the mangosteen stearoyl-ACP thioesterase revealed increases in seed stearic acid levels up to 17%. The subsequent stacked with a soybean event silenced in both palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase activity, resulted in a seed lipid phenotype of approximately 11%-19% stearate and approximately 70% oleate. The oil profile created by the stack was maintained for four generations under greenhouse conditions and a fifth generation under a field environment. However, in generation six and seven under field conditions, the oleate levels decreased to 30%-40%, while the stearic level remained elevated. PMID:24909647

  1. USGS tethered ACP platforms: New design means more safety and accuracy

    USGS Publications Warehouse

    Morlock, S.E.; Stewart, J.A.; Rehmel, M.S.

    2004-01-01

    The US Geological Survey has developed an innovative tethered platform that supports an Acoustic Current Profiler (ACP) in making stream-flow measurements (use of the term ACP in this article refers to a class of instruments and not a specific brand name or model). The tethered platform reduces the hazards involved in conventional methods of stream-flow measurement. The use of the platform reduces or eliminates time spent by personnel in streams and boats or on bridges and cableway and stream-flow measurement accuracy is increased.

  2. High School Political Clubs--A First Amendment Right

    ERIC Educational Resources Information Center

    Levy, Martin R.

    1977-01-01

    The First and Fourteenth Amendments guarantee that high school students may form political clubs. Such clubs should be recognized by the school unless they prevent others from learning, interrupt class, or violate valid school rules. (Author/IRT)

  3. KIND Clubs: A Humane Education Innovation That's Working.

    ERIC Educational Resources Information Center

    Finch, Patty

    1990-01-01

    The Kids in Nature's Defense (KIND) Club and the "adopt" a teacher program are described. The importance of animals and the environment is emphasized. Information on how to start a KIND Club is provided. (KR)

  4. Contextual view to southwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to southwest of Burton Park Club House and Amphitheater (90mm lens). Pedestals within Amphitheater are supports for bench seating - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  5. View of the yacht club facing south from Front Street. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the yacht club facing south from Front Street. Harbor storage building and restrooms are on the left. - San Luis Yacht Club, Avila Pier, South of Front Street, Avila Beach, San Luis Obispo County, CA

  6. Detail, exterior side of doubleplanked north end, Burton Park Club ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, exterior side of double-planked north end, Burton Park Club House, view to south-southwest (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  7. Interior detail, fireplace, main room, Burton Park Club House, view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail, fireplace, main room, Burton Park Club House, view to northwest (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  8. Contextual view to northnorthwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north-northwest of Burton Park Club House and Amphitheater (90 mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  9. Detail, front doors, Burton Park Club House, view to west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, front doors, Burton Park Club House, view to west northwest (135mm lens). Note simplified pilasters flanking doors. - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  10. Contextual view to north of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north of Burton Park Club House and Amphitheater, taken from adjacent circular drive (135mm lens) - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  11. Oblique view, north end and west side, Burton Park Club ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique view, north end and west side, Burton Park Club House, view to south (90mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  12. General view, Belair Bath and Tennis Club, Belair at Bowie, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view, Belair Bath and Tennis Club, Belair at Bowie, Maryland, looking west. - Belair Bath and Tennis Club, Southwest corner of Belair Drive and Tulip Grove Drive, Bowie, Prince George's County, MD

  13. Preparation of fatty-acylated derivatives of acyl carrier protein using Vibrio harveyi acyl-ACP synthetase.

    PubMed

    Shen, Z; Fice, D; Byers, D M

    1992-07-01

    A simple two-step purification of Vibrio harveyi fatty acyl-acyl carrier protein (acyl-ACP) synthetase, which is useful for the quantitative preparation and analysis of fatty-acylated derivatives of ACP, is described. Acyl-ACP synthetase can be partially purified from extracts of this bioluminescent bacterium by Cibacron blue chromatography and Sephacryl S-300 gel filtration and is stable for months at -20 degrees C in the presence of glycerol. Incubation of ACP from Escherichia coli with ATP and radiolabeled fatty acids (6 to 16 carbons in length) in the presence of the enzyme resulted in quantitative conversion to biologically active acylated derivatives. The enzyme reaction can be monitored by a filter disk assay to quantitate levels of ACP or by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and fluorography to detect ACP in cell extracts. With its broad fatty acid chain length specificity and optimal activity in mild nondenaturing buffers, the soluble V. harveyi acyl-ACP synthetase provides an attractive alternative to current chemical and enzymatic methods of acyl-ACP preparation and analysis. PMID:1514693

  14. Integrating Current Meteorological Research Through Club Fundraising

    NASA Astrophysics Data System (ADS)

    Gill, S. S.; Kauffman, C. M.

    2003-12-01

    Earth science programs whose focus is primarily an undergraduate education do not often have the funding to take students to very many conferences which could expose the student to new research as well as possible graduate programs and employment opportunities. Conferences also give the more enthusiastic and hardworking students a venue in which to present their research to the meteorological community. In addition, the California University services largely lower income counties, which make student attendance at conferences even more difficult even though the student in SW PA may be individually motivated. This issue is compounded by the fact that the Meteorology Concentration within the Earth Science department at Cal U is composed of only two full-time Professors, which limits the amount of research students can be exposed to within a classroom setting. New research ideas presented at conferences are thus an important mechanism for broadening what could be an isolated program. One way in which the meteorology program has circumvented the funding problem to a certain extent is through an active student club. With nearly 60 majors (3/4 of which are active in club activities, the meteorology club is able to execute a variety of fundraising activities. Money that is raised can then request from student services matching funds. Further money is given to clubs, which are very active not only in fundraising, but using that money for academic related activities. For the last 3 years the club budget has been in the neighborhood of \\$4500. The money has then been used to partially finance student registration and accommodation costs making conference attendance much more affordable. Normally 8-16 students attend conferences that they would otherwise not be able to attend without great expense. There are times when more than 16 students wish to attend, but travel arrangements prohibit more than 16. Moreover club money is also use to supplement student costs on a summer

  15. Golf players exhibit changes to grip speed parameters during club release in response to changes in club stiffness.

    PubMed

    Osis, Sean T; Stefanyshyn, Darren J

    2012-02-01

    The influence of golf club stiffness on driving performance is currently unclear, and it is possible that this ambiguity is due in part to golfer adaptation to equipment. The purpose of the current study was to elucidate mechanisms of adaptation to club stiffness, during the golf swing, by employing tendon vibration to distort proprioceptive feedback. Vibration (∼50 Hz, ∼1 mm amplitude) was applied to the upper extremities of 24 golfers using DC motors with eccentric weights. Golfers hit golf balls in a laboratory setting using three clubs of varying shaft stiffness, and club kinematics were recorded using high speed (180 Hz) digital cameras. The results demonstrated significant slowing of the club grip during club release for a high-stiffness shaft with vibration. This suggests that, when proprioceptive feedback is available, players adapt to changes in club stiffness by modifying the release dynamics of the club late in the downswing. PMID:21820748

  16. A Librarian's Planning Handbook for the Texas Reading Club.

    ERIC Educational Resources Information Center

    Phelan, Jody

    Developed for the Texas Reading Club, a program sponsored cooperatively by local libraries and the Texas State Library and designed to encourage children and their parents to read and use the library, this planning handbook is intended to help librarians and volunteers organize and manage a local reading club. The Texas Reading Club program is…

  17. Health Promotion Guidance Activity of Youth Sports Clubs

    ERIC Educational Resources Information Center

    Kokko, Sami; Kannas, Lasse; Villberg, Jari; Ormshaw, Michael

    2011-01-01

    Purpose: This paper aims to clarify the extent to which youth sports clubs guide their coaches to recognise health promotion as a part of the coaching practice. The guidance activity of clubs is seen parallel to internal organisational communication. Design/methodology/approach: A survey of 93 (from 120, 78 per cent) youth sports clubs in Finland…

  18. An Exploration of Recent Club Drug Use among Rave Attendees

    ERIC Educational Resources Information Center

    Yacoubian, George S.; Peters, Ronald J.

    2007-01-01

    Raves are characterized by large numbers of youth dancing for long periods of time and by the use of "club drugs," such as 3, 4-methylenedioxymethamphetamine (MDMA or "ecstasy"). While a small body of research has explored the use of ecstasy and other club drugs (EOCD) among club rave attendees in the United States, we are aware of no studies that…

  19. Contextual view to northwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to northwest of Burton Park Club House and Amphitheater. Steps lead up from wings of stage area to club house grade level (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  20. The 4-H Club Meeting: An Essential Youth Development Strategy

    ERIC Educational Resources Information Center

    Cassels, Alicia; Post, Liz; Nestor, Patrick I.

    2015-01-01

    The club meeting has served as a key delivery method for 4-H programming across the United States throughout its history. A survey of WV 4-H community club members reinforces the body of evidence that the 4-H club meeting is an effective vehicle for delivering positive youth learning opportunities within the umbrella of the Essential Elements of…

  1. 5. INTERIOR VIEW OF THE CLUB MODERNE LOUNGE SHOWING EXAMPLES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. INTERIOR VIEW OF THE CLUB MODERNE LOUNGE SHOWING EXAMPLES OF THE LEATHER COVERED BOOTHS INSTALLED IN 19486. FACADE OF THE CLUB MODERNE, SHOWING THE ORIGINAL CURVED CORNER PROFILE AND TRI-COLOR CARRERE GLASS FACADE. - Anaconda Historic District, Club Moderne, 801 East Park Avenue, Anaconda, Deer Lodge County, MT

  2. Brown & Gold Club Member Survey: What Senior Adults Want.

    ERIC Educational Resources Information Center

    Conklin, Karen A.

    In order to better serve the senior population in its community, Johnson County Community College (JCCC) (Kansas) created the Brown and Gold Club (named after the school colors), which offers JCCC education and special events to adults age 55 and over. Membership in the club now exceeds 4,800 people. Not only does the club serve the senior…

  3. Power and control in gay strip clubs.

    PubMed

    DeMarco, Joseph R G

    2007-01-01

    The gay strip club is a place in which more than displays of male beauty take place. The mix of customers, performers, liquor, and nudity results in fascinating dynamics. Of interest in this article are the power relationships and issues of control played out both among and between strippers and customers. Based on extensive participant observation conducted in eight cities and numerous bars/clubs and including more than 150 in-depth interviews, this article concerns just one aspect of the world of male strippers who perform for men. PMID:18019071

  4. What's in a Number? Estimating numbers of viable Candidatus Liberibacter asiaticus cells in citrus and ACP

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Knowledge of CLas viability is critical for answering questions about how the organism is proliferating within citrus and ACP, what is the response to therapeutic treatments, and for understanding disease development. Because CLas cannot be grown in culture, estimating cell viability has not been po...

  5. Introducing an Absolute Cavity Pyrgeometer (ACP) for Improving the Atmospheric Longwave Irradiance Measurement (Poster)

    SciTech Connect

    Reda, I.; Stoffel, T.

    2012-03-01

    Advancing climate change research requires accurate and traceable measurement of the atmospheric longwave irradiance. Current measurement capabilities are limited to an estimated uncertainty of larger than +/- 4 W/m2 using the interim World Infrared Standard Group (WISG). WISG is traceable to the Systeme international d'unites (SI) through blackbody calibrations. An Absolute Cavity Pyrgeometer (ACP) is being developed to measure absolute outdoor longwave irradiance with traceability to SI using the temperature scale (ITS-90) and the sky as the reference source, instead of a blackbody. The ACP was designed by NREL and optically characterized by the National Institute of Standards and Technology (NIST). Under clear-sky and stable conditions, the responsivity of the ACP is determined by lowering the temperature of the cavity and calculating the rate of change of the thermopile output voltage versus the changing net irradiance. The absolute atmospheric longwave irradiance is then calculated with an uncertainty of +/- 3.96 W/m2 with traceability to SI. The measured irradiance by the ACP was compared with the irradiance measured by two pyrgeometers calibrated by the World Radiation Center with traceability to the WISG.

  6. GUIDE FOR SELF-EXAMINATION AND PLANNING, THE CLUB ANALYSIS PROGRAM OF INDUSTRIAL MANAGEMENT CLUBS OF THE YMCA.

    ERIC Educational Resources Information Center

    MEYER, WILLIAM F.

    THIS GUIDE PROVIDES A QUESTION AND ANSWER METHOD IN WHICH LEADERS OF INDUSTRIAL MANAGEMENT CLUBS (IMC) MAY EVALUATE CLUB PROGRESS AND ACCOMPLISHMENTS. A REPORT OF A NATIONAL STUDY MADE BY GEORGE WILLIAMS COLLEGE ON I.M.C. MEMBERS AND THEIR ATTITUDES TOWARD CLUB PROGRESS IS PROVIDED AS A GUIDE FOR GATHERING INFORMATION. A SMALL CORE STEERING…

  7. Constitutional Law--State Action--Golden v. Biscayne Bay Yacht Club: Preventing Discrimination by Private Clubs

    ERIC Educational Resources Information Center

    Patrick, Michael W.

    1976-01-01

    Although the Supreme Court has refrained from answering whether the membership policies of private clubs can be attacked on state action grounds, the Fifth Circuit Court of Appeals held in the affirmative in Golden v. Biscayne Bay Yacht Club. It ruled that leasing publicly owned bay bottom land to a yacht club constituted sufficient state…

  8. Lights, camera and action: learning necrophilia in a psychiatry movie club.

    PubMed

    Kalra, Gurvinder S

    2013-04-01

    Kissed (1996) is a serious film that portrays the disturbing and taboo issue of necrophilia in a delicate and viewer friendly way. Being a rare paraphilia, it may sometimes be difficult to get necrophilia related literature or even understand this complex behavior. An interested person may have to rely on the few case reports from forensic journals or law books in order to understand what and how necrophiles do what they do! A movie club can be an interesting and novel way to learn various issues in medicine and psychiatry, including necrophilia. This paper discusses the use of this film in academic sessions in order to learn necrophilia. PMID:23472790

  9. Topics for Mathematics Clubs. Second Edition.

    ERIC Educational Resources Information Center

    Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

    One of the main purposes of a mathematics club is to provide the opportunity for students to study exciting topics in mathematics not ordinarily discussed in the classroom. Each of the 10 chapters in this booklet is a collection of related subtopics. Each idea is presented and discussed; bibliographies then suggest in-depth reading. The chapters…

  10. Operations Course Icebreaker: Campus Club Cupcakes Exercise

    ERIC Educational Resources Information Center

    Snider, Brent; Southin, Nancy

    2016-01-01

    Campus Club Cupcakes is an in-class "introduction to operations management" experiential learning exercise which can be used within minutes of starting the course. After reading the one-page mini case, students are encouraged to meet each other and collaborate to determine if making and selling cupcakes to fellow business students would…

  11. Dr. von Braun Visits Huntsville Boys Club

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

  12. The Academic Clubs: Theory to Practice

    ERIC Educational Resources Information Center

    Bicknell, Noel

    2010-01-01

    The Lab School of Washington (LSW) uses a unique approach to teaching social studies and humanities content. As part of its arts-driven lower school program, each child spends 40 minutes a day in dedicated rooms that simulate a specific historical time and place. Called "academic clubs," teachers use these spaces to teach thematic, arts-based,…

  13. Clubs Reach Urban Middle Level Students.

    ERIC Educational Resources Information Center

    Hale, Rosalind P.

    1993-01-01

    When busing limits number of afternoon activities and students do not seem interested anyway, principals must look for opportunities during day to involve students. One inner-city middle-school principal helped teachers initiate program of morning clubs and assemblies to increase student self-esteem and encourage student and parent involvement…

  14. Radio Clubs of Niger: September, 1972.

    ERIC Educational Resources Information Center

    McAnany, Emile G.

    The Radio Club Association of Niger (ARCN) is a private agency and has been in operation for ten years under the guidance of the radio section of the Ministry of Information. The primary objective of this project is not the assimilation of information but the growth in awareness of their situation by local people. Most of the program therefore…

  15. Advice on Setting up a STEM Club

    ERIC Educational Resources Information Center

    Khan, Faisal

    2013-01-01

    Setting up a STEM club can be the most daunting item that one faces on a department's development plan. Coupled with all the other demands that exist within teaching and learning, teachers can be easily forgiven for pushing this task further and further into the school year until it eventually becomes one of next year's "to-do" items.…

  16. Journal bearing

    DOEpatents

    Menke, John R.; Boeker, Gilbert F.

    1976-05-11

    1. An improved journal bearing comprising in combination a non-rotatable cylindrical bearing member having a first bearing surface, a rotatable cylindrical bearing member having a confronting second bearing surface having a plurality of bearing elements, a source of lubricant adjacent said bearing elements for supplying lubricant thereto, each bearing element consisting of a pair of elongated relatively shallowly depressed surfaces lying in a cylindrical surface co-axial with the non-depressed surface and diverging from one another in the direction of rotation and obliquely arranged with respect to the axis of rotation of said rotatable member to cause a flow of lubricant longitudinally along said depressed surfaces from their distal ends toward their proximal ends as said bearing members are rotated relative to one another, each depressed surface subtending a radial angle of less than 360.degree., and means for rotating said rotatable bearing member to cause the lubricant to flow across and along said depressed surfaces, the flow of lubricant being impeded by the non-depressed portions of said second bearing surface to cause an increase in the lubricant pressure.

  17. Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.

    PubMed

    Kremer, Laurent; Dover, Lynn G; Carrère, Séverine; Nampoothiri, K Madhavan; Lesjean, Sarah; Brown, Alistair K; Brennan, Patrick J; Minnikin, David E; Locht, Camille; Besra, Gurdyal S

    2002-06-01

    Mycolic acids consist of long-chain alpha-alkyl-beta-hydroxy fatty acids that are produced by successive rounds of elongation catalysed by a type II fatty acid synthase (FAS-II). A key feature in the elongation process is the condensation of a two-carbon unit from malonyl-acyl-carrier protein (ACP) to a growing acyl-ACP chain catalysed by a beta-ketoacyl-ACP synthase (Kas). In the present study, we provide evidence that kasA from Mycobacterium tuberculosis encodes an enzyme that elongates in vivo the meromycolate chain, in both Mycobacterium smegmatis and Mycobacterium chelonae. We demonstrate that KasA belongs to the FAS-II system, which utilizes primarily palmitoyl-ACP rather than short-chain acyl-ACP primers. Furthermore, in an in vitro condensing assay using purified recombinant KasA, palmitoyl-AcpM and malonyl-AcpM, KasA was found to express Kas activity. Also, mutated KasA proteins, with mutation of Cys(171), His(311), Lys(340) and His(345) to Ala abrogated the condensation activity of KasA in vitro completely. Finally, purified KasA was highly sensitive to cerulenin, a well-known inhibitor of Kas, which may lead to the development of novel anti-mycobacterial drugs targeting KasA. PMID:12023885

  18. Solution Structure of 4'-Phosphopantetheine - GmACP3 from Geobacter Metallireducens: A Specialized Acyl Carrier Protein with Atypical Structural Features and a Putative Role in Lipopolysaccharide Biosyntheses

    SciTech Connect

    Ramelot, Theresa A.; Smola, Matthew J.; Lee, Hsiau-Wei; Ciccosanti, Colleen; Hamilton, Keith; Acton, Thomas; Xiao, Rong; Everett, John K.; Prestegard, James H.; Montelione, Gaetano; Kennedy, Michael A.

    2011-03-08

    GmACP3 from Geobacter metallireducens is a specialized acyl carrier protein (ACP) whose gene, gmet_2339, is located near genes encoding many proteins involved in lipopolysaccharide (LPS) biosynthesis, indicating a likely function for GmACP3 in LPS production. By overexpression in Escherichia coli, about 50% holo-GmACP3 and 50% apo-GmACP3 were obtained. Apo-GmACP3 exhibited slow precipitation and non-monomeric behavior by 15NNMRrelaxation measurements. Addition of 4'-phosphopantetheine (4'-PP) via enzymatic conversion by E. coli holo-ACP synthase resulted in stable >95% holo-GmACP3 that was characterized as monomeric by 15N relaxation measurements and had no indication of conformational exchange. We have determined a high-resolution solution structure of holo-GmACP3 by standard NMR methods, including refinement with two sets of NH residual dipolar couplings, allowing for a detailed structural analysis of the interactions between 4'-PP and GmACP3. Whereas the overall four helix bundle topology is similar to previously solved ACP structures, this structure has unique characteristics, including an ordered 4'-PP conformation that places the thiol at the entrance to a central hydrophobic cavity near a conserved hydrogen-bonded Trp-His pair. These residues are part of a conservedWDSLxH/N motif found in GmACP3 and its orthologs. The helix locations and the large hydrophobic cavity are more similar tomediumand long-chain acyl-ACPs than to other apo- and holo-ACP structures. Taken together, structural characterization along with bioinformatic analysis of nearby genes suggests that GmACP3 is involved in lipid A acylation, possibly by atypical long-chain hydroxy fatty acids, and potentially is involved in synthesis of secondary metabolites.

  19. Prevalence and Predictors of Club Drug Use among Club-Going Young Adults in New York City

    PubMed Central

    Kelly, Brian C.; Wells, Brooke E.

    2006-01-01

    Club drugs” encompass a diverse range of substances. Although efforts have been made to determine the extent of club drug use among the general population, it is equally important to assess patterns of use among key target populations from which drug trends typically diffuse. This paper describes the results of a survey focused upon club drug use among club-going young adults in NYC. Time-space sampling generated a sample of 1,914 club-going young adults (ages 18–29) who provided data on their use of six key club drugs: ecstasy, ketamine, cocaine, methamphetamine, GHB, and LSD, as well as data on their gender, sexual orientation, race/ethnicity, and other demographic variables. Club-going young adults report drug use at high rates—70% report lifetime illicit drug use and 22% report recent club drug use. Rates of club drug use differ by gender, sexual orientation and race/ethnicity. Male gender is predictive of ketamine, GHB, and methamphetamine use, while female gender is predictive of cocaine use. Gay/bisexual orientation and White race are predictive of the use of several club drugs. Greater health promotion efforts are warranted among this population. Intervention programs and campaigns should tailor specific drug messages to differentially target various segments of dance club patrons. PMID:16937088

  20. Results of First Outdoor Comparison Between Absolute Cavity Pyrgeometer (ACP) and Infrared Integrating Sphere (IRIS) Radiometer at PMOD (Presentation)

    SciTech Connect

    Reda, I.; Grobner, J.; Wacker, S.; Stoffel, T.

    2013-03-01

    The ACP and IRIS are developed to establish a world reference for calibrating pyrgeometers with traceability to SI units. The two radiometers are unwindowed with negligible spectral dependence, and traceable to SI units through the temperature scale (ITS-90). The first outdoor comparison between the two designs was held from January 28 to February 8, 2013 at the Physikalisch-Metorologisches Observatorium Davos (PMOD). The difference between the irradiance measured by ACP and that of IRIS was within 1 W/m2. A difference of 5 W/m2 was observed between the irradiance measured by ACP&IRIS and that of the interim World Infrared Standard Group (WISG).

  1. Effects of the addition of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on mechanical properties of luting and lining glass ionomer cement

    NASA Astrophysics Data System (ADS)

    Heravi, Farzin; Bagheri, Hossein; Rangrazi, Abdolrasoul; Mojtaba Zebarjad, Seyed

    2016-07-01

    Recently, the addition of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into glass ionomer cements (GICs) has attracted interest due to its remineralization of teeth and its antibacterial effects. However, it should be investigated to ensure that the incorporation of CPP-ACP does not have significant adverse effects on its mechanical properties. The purpose of this study was to evaluate the effects of the addition of CPP-ACP on the mechanical properties of luting and lining GIC. The first step was to synthesize the CPP-ACP. Then the CPP-ACP at concentrations of 1%, 1.56% and 2% of CPP-ACP was added into a luting and lining GIC. GIC without CPP-ACP was used as a control group. The results revealed that the incorporation of CPP-ACP up to 1.56%(w/w) increased the flexural strength (29%), diametral tensile strength (36%) and microhardness (18%), followed by a reduction in these mechanical properties at 2%(w/w) CPP-ACP. The wear rate was significantly decreased (23%) in 1.56%(w/w) concentration of CPP-ACP and it was increased in 2%(w/w). Accordingly, the addition of 1.56%(w/w) CPP-ACP into luting and lining GIC had no adverse effect on the mechanical properties of luting and lining GIC and could be used in clinical practice.

  2. Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

    PubMed

    Mdluli, K; Slayden, R A; Zhu, Y; Ramaswamy, S; Pan, X; Mead, D; Crane, D D; Musser, J M; Barry, C E

    1998-06-01

    Although isoniazid (isonicotinic acid hydrazide, INH) is widely used for the treatment of tuberculosis, its molecular target has remained elusive. In response to INH treatment, saturated hexacosanoic acid (C26:0) accumulated on a 12-kilodalton acyl carrier protein (AcpM) that normally carried mycolic acid precursors as long as C50. A protein species purified from INH-treated Mycobacterium tuberculosis was shown to consist of a covalent complex of INH, AcpM, and a beta-ketoacyl acyl carrier protein synthase, KasA. Amino acid-altering mutations in the KasA protein were identified in INH-resistant patient isolates that lacked other mutations associated with resistance to this drug. PMID:9616124

  3. Transition metal HE`s - VII ACP. Progress report, August 1971--October 1971

    SciTech Connect

    Clink, G.L.

    1998-12-31

    Physical and physicochemical properties of hexaamminechromium III perchlorate (ACP) were investigated to determine its potentiality for HE and/or HE component application. Physicochemical properties obtained through investigation of isothermally aged ACP under conditions of various system and boundary restrictions (open and closed; 50 and 80 C; 0.65 and 0.85 g/cc) show the material to be substantially stable under these simulated isothermal storage conditions from a standpoint of infrared and DTA thermal pattern behavior and chemical analysis of aged residues. Spark sensitivity was 0.25 joules at 5 kv (by LASL type test) and impact sensitivity was about 23 and 14 cm on sandpaper (12A) and steel (12B), respectively.

  4. Journalism Education in Canada.

    ERIC Educational Resources Information Center

    MacDonald, Dick; Russell, Catharine

    Twenty-four of the 35 Canadian schools with formal journalism programs responded to a survey conducted to collect data about enrollment, curricula, faculty background in journalism, and the ability of journalism graduates to find jobs in the profession. Highlights of the results are as follows: there are an estimated 3,300 journalism students in…

  5. Effect of CPP-ACP Paste on Dental Caries in Primary Teeth

    PubMed Central

    Sitthisettapong, T.; Phantumvanit, P.; Huebner, C.; DeRouen, T.

    2012-01-01

    This clinical trial tested the effect of daily application of 10% w/v calcium phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste for 1 yr when added to regular toothbrushing with fluoridated toothpaste to prevent dental caries in pre-school children. High-caries-risk children aged 2½ to 3½ yrs in a suburban area of central Thailand were assigned to receive either CPP-ACP (n = 150) or a placebo control (n = 146) in addition to fluoridated toothpaste. The International Caries Detection and Assessment System (ICDAS) was recorded at baseline, 6 mos, and 1 yr. At 1 yr, a significant increase in mean numbers of enamel and dentin caries lesions, as well as dmfs, was found in both groups (p < 0.001). No significant difference was observed between groups on these 3 outcome measures (p = 0.23, 0.84, and 0.91, respectively). The odds of enamel caries lesion transitions to a state of regression or stability, compared with progression from baseline, was also not different between groups [OR = 1.00, 95% CI (0.86, 1.17)]. This trial found that daily application of 10% w/v CPP-ACP paste on school days for 1 yr, when added to regular toothbrushing with a fluoride toothpaste, had no significant added effect in preventing caries in the primary dentition of these pre-school children (ClinicalTrials.gov number CT01 604109). PMID:22805294

  6. Effect of CPP-ACP paste on dental caries in primary teeth: a randomized trial.

    PubMed

    Sitthisettapong, T; Phantumvanit, P; Huebner, C; Derouen, T

    2012-09-01

    This clinical trial tested the effect of daily application of 10% w/v calcium phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste for 1 yr when added to regular toothbrushing with fluoridated toothpaste to prevent dental caries in pre-school children. High-caries-risk children aged 2½ to 3½ yrs in a suburban area of central Thailand were assigned to receive either CPP-ACP (n = 150) or a placebo control (n = 146) in addition to fluoridated toothpaste. The International Caries Detection and Assessment System (ICDAS) was recorded at baseline, 6 mos, and 1 yr. At 1 yr, a significant increase in mean numbers of enamel and dentin caries lesions, as well as dmfs, was found in both groups (p < 0.001). No significant difference was observed between groups on these 3 outcome measures (p = 0.23, 0.84, and 0.91, respectively). The odds of enamel caries lesion transitions to a state of regression or stability, compared with progression from baseline, was also not different between groups [OR = 1.00, 95% CI (0.86, 1.17)]. This trial found that daily application of 10% w/v CPP-ACP paste on school days for 1 yr, when added to regular toothbrushing with a fluoride toothpaste, had no significant added effect in preventing caries in the primary dentition of these pre-school children (ClinicalTrials.gov number CT01 604109). PMID:22805294

  7. Histochemical localization and characterization of AKP, ACP, NSE, and POD from cultured Apostichopus japonicus

    NASA Astrophysics Data System (ADS)

    Li, Jiye; Sun, Xiuqin; Zheng, Fengrong; Sun, Hushan

    2009-09-01

    We investigated the distribution of four enzymes involved in the immune response of Apostichopus japonicus. We collected samples of the tentacles, papillate podium, integument, respiratory tree, and digestive tract and stained them for acid phosphatase (ACP), alkaline phosphatase (AKP), non-specific esterase (NSE) and peroxidase (POD) activity. The distribution and content of ACP, AKP, NSE, and POD differed among the tissues. The coelomic epithelium of the tentacle, papillate podium, and integument and the mucous layer of respiratory tree were positive for ACP activity. The coelomic epithelium and cuticular layer of the tentacle, papillate podium, and integument and the mucous layer and tunica externa of the respiratory tree and digestive tract stained positive or weakly positive for AKP activity. Almost all the epithelial tissues stained positive, strongly positive, or very strongly positive for NSE activity. The cuticular layer of the tentacle and integument and the mucous layer, tunica submucosa, and tunica externa of the respiratory tree and digestive tract stained positive for POD activity. We hypothesize that these enzymes play a role in the immune response in A. japonicus.

  8. The rich club phenomenon in the classroom

    PubMed Central

    Vaquero, Luis M.; Cebrian, Manuel

    2013-01-01

    We analyse the evolution of the online interactions held by college students and report on novel relationships between social structure and performance. Our results indicate that more frequent and intense social interactions generally imply better score for students engaging in them. We find that these interactions are hosted within a “rich-club”, mediated by persistent interactions among high performing students, which is created during the first weeks of the course. Low performing students try to engage in the club after it has been initially formed, and fail to produce reciprocity in their interactions, displaying more transient interactions and higher social diversity. Furthermore, high performance students exchange information by means of complex information cascades, from which low performing students are selectively excluded. Failure to engage in the rich club eventually decreases these students' communication activity towards the end of the course. PMID:23378908

  9. A Unifying Framework for Measuring Weighted Rich Clubs

    NASA Astrophysics Data System (ADS)

    Alstott, Jeff; Panzarasa, Pietro; Rubinov, Mikail; Bullmore, Edward T.; Vértes, Petra E.

    2014-12-01

    Network analysis can help uncover meaningful regularities in the organization of complex systems. Among these, rich clubs are a functionally important property of a variety of social, technological and biological networks. Rich clubs emerge when nodes that are somehow prominent or `rich' (e.g., highly connected) interact preferentially with one another. The identification of rich clubs is non-trivial, especially in weighted networks, and to this end multiple distinct metrics have been proposed. Here we describe a unifying framework for detecting rich clubs which intuitively generalizes various metrics into a single integrated method. This generalization rests upon the explicit incorporation of randomized control networks into the measurement process. We apply this framework to real-life examples, and show that, depending on the selection of randomized controls, different kinds of rich-club structures can be detected, such as topological and weighted rich clubs.

  10. The Fuel Cell Powered Club Car Carryall

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2005-01-01

    The NASA Glenn Research Center initiated development of the Fuel Cell Powered Club Car Carryall as a way to reduce pollution in industrial settings, reduce fossil fuel consumption and reduce operating costs for transportation systems. The Club Car Carryall provides an inexpensive approach to advance the state of the art in electric vehicle technology in a practical application. The project transfers space technology to terrestrial use via non-traditional partners, and provides power system data valuable for future aeronautics and space applications. The work was done under the Hybrid Power Management (HPM) Program. The Carryall is a state of the art, dedicated, electric utility vehicle. Hydrogen powered proton exchange membrane (PEM) fuel cells are the primary power source. Ultracapacitors were used for energy storage as long life, maintenance free operation, and excellent low temperature performance is essential. Metal hydride hydrogen storage was used to store hydrogen in a safe and efficient low-pressure solid form. The report concludes that the Fuel Cell Powered Club Car Carryall can provide excellent performance, and that the implementation of fuel cells in conjunction with ultracapacitors in the power system can provide significant reliability and performance improvements.

  11. Acyl-ACP thioesterases from macadamia (Macadamia tetraphylla) nuts: cloning, characterization and their impact on oil composition.

    PubMed

    Moreno-Pérez, Antonio J; Sánchez-García, Alicia; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2011-01-01

    The mechanisms by which macadamia nuts accumulate the unusual palmitoleic and asclepic acyl moieties, which constitute up to 20% of the fatty acids in some varieties, are still unknown. Acyl-acyl carrier protein (ACP) thioesterases (EC 3.1.2.14) are intraplastidial enzymes that terminate the synthesis of fatty acids in plants and that facilitate the export of the acyl moieties to the endoplasmic reticulum where they can be used in the production of glycerolipids. Here, we have investigated the possible role of acyl-ACP thioesterase activity in the composition of macadamia kernel oil. Accordingly, two acyl-ACP thioesterases were cloned from developing macadamia kernels, one of the FatA type and the other of the FatB type. These enzymes were heterologously expressed in Escherichia coli, and the recombinant thioesterases were purified, characterized kinetically and assayed with a variety of substrates, demonstrating the high specificity of macadamia FatA towards 16:1-ACP. Acyl-ACP thioesterase activity was also characterized in crude extracts from two different varieties of macadamia, Cate and Beaumont, which accumulate different amounts of n-7 fatty acids. The impact of acyl-ACP thioesterase activities on the oil composition of these kernels is discussed in the light of these results. PMID:21071236

  12. A Book Club Sheds Light on Boys and Reading

    ERIC Educational Resources Information Center

    Weih, Timothy G.

    2008-01-01

    This article is about a book club for middle school boys. The idea of a book club for boys came from the author's concern about what he had been hearing and reading about boys falling behind in their reading abilities. The purpose of establishing the club was to discover from the boys themselves what could be done to support them in their reading.…

  13. Experiences of participating in an antiretroviral treatment adherence club

    PubMed Central

    Dudhia, Raashika; Kagee, Ashraf

    2015-01-01

    In an effort to streamline the management of large numbers of patients receiving antiretroviral therapy (ART) in South Africa, adherence clubs were introduced in some districts in the Western Cape since 2008. Adherence clubs are group clinic visits of approximately thirty ART users who receive group adherence counselling and obtain a supply of medication. We sought to document the experiences of patients attending adherence clubs and health care workers at clinics where clubs were operating. Participants were six ART adherence club members and seven health care workers, which included HIV nurses, medical doctors, pharmacists and counsellors. Data in the form of one-on-one interviews were collected at the Infectious Diseases Clinic of a large district hospital in a peri-urban area in the Western Cape region of South Africa. The interviews covered ART users’ experiences of the clubs, advantages and challenges that arose in the context of the club-based method of providing treatment, and the concerns facing ART users and health care workers (HCW’s) with regard to the clubs. The data were analysed using thematic analysis. There were clear benefits to the introduction of adherence clubs, most importantly the reduced amount of time ART users needed to spend at the clinic. Yet, various problems also emerged, the most important one being the logistical problems associated with the timely and correct delivery of drugs. These benefits and disadvantages are discussed in the context of providing ART services to large numbers of patients in post-apartheid South Africa. PMID:25168720

  14. Identification of Genes Required for Secretion of the Francisella Oxidative Burst-Inhibiting Acid Phosphatase AcpA.

    PubMed

    Hoang, Ky Van; Chen, Carolyn G; Koopman, Jacob; Moshiri, Jasmine; Adcox, Haley E; Gunn, John S

    2016-01-01

    Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing. Our previous studies have shown that after entering its primary cellular host, the macrophage, Francisella immediately suppresses the oxidative burst by secreting a series of acid phosphatases including AcpA-B-C and HapA, thereby evading the innate immune response of the macrophage and enhancing survival and further infection. However, the mechanism of acid phosphatase secretion by Francisella is still unknown. In this study, we screened for genes required for AcpA secretion in Francisella. We initially demonstrated that the known secretion systems, the putative Francisella-pathogenicity island (FPI)-encoded Type VI secretion system and the Type IV pili, do not secrete AcpA. Using random transposon mutagenesis in conjunction with ELISA, Western blotting and acid phosphatase enzymatic assays, a transposon library of 5450 mutants was screened for strains with a minimum 1.5-fold decrease in secreted (culture supernatant) AcpA, but no defect in cytosolic AcpA. Three mutants with decreased supernatant AcpA were identified. The transposon insertion sites of these mutants were revealed by direct genomic sequencing or inverse-PCR and sequencing. One of these mutants has a severe defect in AcpA secretion (at least 85% decrease) and is a predicted hypothetical inner membrane protein. Interestingly, this mutant also affected the secretion of the FPI-encoded protein, VgrG. Thus, this screen identified novel protein secretion factors involved in the subversion of host defenses. PMID:27199935

  15. Identification of Genes Required for Secretion of the Francisella Oxidative Burst-Inhibiting Acid Phosphatase AcpA

    PubMed Central

    Hoang, Ky Van; Chen, Carolyn G.; Koopman, Jacob; Moshiri, Jasmine; Adcox, Haley E.; Gunn, John S.

    2016-01-01

    Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing. Our previous studies have shown that after entering its primary cellular host, the macrophage, Francisella immediately suppresses the oxidative burst by secreting a series of acid phosphatases including AcpA-B-C and HapA, thereby evading the innate immune response of the macrophage and enhancing survival and further infection. However, the mechanism of acid phosphatase secretion by Francisella is still unknown. In this study, we screened for genes required for AcpA secretion in Francisella. We initially demonstrated that the known secretion systems, the putative Francisella-pathogenicity island (FPI)-encoded Type VI secretion system and the Type IV pili, do not secrete AcpA. Using random transposon mutagenesis in conjunction with ELISA, Western blotting and acid phosphatase enzymatic assays, a transposon library of 5450 mutants was screened for strains with a minimum 1.5-fold decrease in secreted (culture supernatant) AcpA, but no defect in cytosolic AcpA. Three mutants with decreased supernatant AcpA were identified. The transposon insertion sites of these mutants were revealed by direct genomic sequencing or inverse-PCR and sequencing. One of these mutants has a severe defect in AcpA secretion (at least 85% decrease) and is a predicted hypothetical inner membrane protein. Interestingly, this mutant also affected the secretion of the FPI-encoded protein, VgrG. Thus, this screen identified novel protein secretion factors involved in the subversion of host defenses. PMID:27199935

  16. Isolation of Vibrio harveyi acyl carrier protein and the fabG, acpP, and fabF genes involved in fatty acid biosynthesis.

    PubMed Central

    Shen, Z; Byers, D M

    1996-01-01

    We report the isolation of Vibrio harveyi acyl carrier protein (ACP) and cloning of a 3,973-bp region containing the fabG (encoding 3-ketoacyl-ACP reductase, 25.5 kDa), acpP (encoding ACP, 8.7 kDa), fabF (encoding 3-ketoacyl-ACP synthase II, 43.1 kDa), and pabC (encoding aminodeoxychorismate lyase, 29.9 kDa) genes. Predicted amino acid sequences were, respectively, 78, 86, 76, and 35% identical to those of the corresponding Escherichia coli proteins. Five of the 11 sequence differences between V. harveyi and E. coli ACP were nonconservative amino acid differences concentrated in a loop region between helices I and II. PMID:8550484

  17. Has Communication Explained Journalism?

    ERIC Educational Resources Information Center

    Zelizer, Barbie

    1993-01-01

    Argues for a more interdisciplinary approach to journalism scholarship to provide a fuller account of media power. Considers briefly the notions of performance, narrative, ritual, and interpretive community as alternative frames through which to consider journalism. (SR)

  18. Analyzing Children's Science Journals.

    ERIC Educational Resources Information Center

    Shepardson, Daniel P.; Britsch, Susan J.

    2000-01-01

    Explains the process of using science journals with first and second grade students in three activities to explore the instructional sequence. Suggests some strategies to use journals more effectively and makes recommendations on important points for student evaluation. (YDS)

  19. Development of the ACP safeguards neutron counter for PWR spent fuel rods

    NASA Astrophysics Data System (ADS)

    Lee, Tae-Hoon; Menlove, Howard O.; Lee, Sang-Yoon; Kim, Ho-Dong

    2008-04-01

    An advanced neutron multiplicity counter has been developed for measuring spent fuel in the Advanced spent fuel Conditioning Process (ACP) at the Korea Atomic Energy Research Institute (KAERI). The counter uses passive neutron multiplicity counting to measure the 244Cm content in spent fuel. The input to the ACP process is spent fuel from pressurized water reactors (PWRs), and the high intensity of the gamma-ray exposure from spent fuel requires a careful design of the counter to measure the neutrons without gamma-ray interference. The nuclear safeguards for the ACP facility requires the measurement of the spent fuel input to the process and the Cm/Pu ratio for the plutonium mass accounting. This paper describes the first neutron counter that has been used to measure the neutron multiplicity distribution from spent fuel rods. Using multiple samples of PWR spent fuel rod-cuts, the singles (S), doubles (D), and triples (T) rates of the neutron distribution for the 244Cm nuclide were measured and calibration curves were produced. MCNPX code simulations were also performed to obtain the three counting rates and to compare them with the measurement results. The neutron source term was evaluated by using the ORIGEN-ARP code. The results showed systematic difference of 21-24% in the calibration graphs between the measured and simulation results. A possible source of the difference is that the burnup codes have a 244Cm uncertainty greater than ±15% and it would be systematic for all of the calibration samples. The S/D and D/T ratios are almost constant with an increment of the 244Cm mass, and this indicates that the bias is in the 244Cm neutron source calculation using the ORIGEN-ARP source code. The graphs of S/D and D/T ratios show excellent agreement between measurement and MCNPX simulation results.

  20. Combining CPP-ACP with fluoride: a synergistic remineralization potential of artificially demineralized enamel or not?

    NASA Astrophysics Data System (ADS)

    El-Sayad, I. I.; Sakr, A. K.; Badr, Y. A.

    2008-08-01

    Background and objective: Minimal intervention dentistry (MID) calls for early detection and remineralization of initial demineralization. Laser fluorescence is efficient in detecting changes in mineral tooth content. Recaldent is a product of casein phosphopeptide-amorphous calcium phosphate (CPP- ACP) which delivers calcium and phosphate ions to enamel. A new product which also contains fluoride is launched in United States. The remineralizing potential of CPP- ACP per se, or when combined with 0.22% Fl supplied in an oral care gel on artificially demineralised enamel using laser fluorescence was investigated. Methods: Fifteen sound human molars were selected. Mesial surfaces were tested using He-Cd laser beam at 441.5nm with 18mW power as excitation source on a suitable set-up based on Spex 750 M monochromator provided with PMT for detection of collected auto-fluorescence from sound enamel. Mesial surfaces were subjected to demineralization for ten days. The spectra from demineralized enamel were measured. Teeth were then divided according to the remineralizing regimen into three groups: group I recaldent per se, group II recaldent combined with fluoride gel and group III artificial saliva as a positive control. After following these protocols for three weeks, the spectra from remineralized enamel from the three groups were measured. The spectra of enamel auto-fluorescence were recorded and normalized to peak intensity at about 540 nm to compare between spectra from sound, demineralized and remineralized enamel surfaces. Results: A slight red shift was noticed in spectra from demineralized enamel, while a blue shift may occur in remineralized enamel. Group II showed the highest remineralizing potential. Conclusions: Combining fluoride with CPP-ACP had a synergistic effect on enamel remineralization. In addition, laser auto-fluorescence is an accurate technique for assessment of changes in tooth enamel minerals.

  1. Scientific Journalism in Armenia

    NASA Astrophysics Data System (ADS)

    Farmanyan, S. V.; Mickaelian, A. M.

    2015-07-01

    In the present study, the problems of scientific journalism and activities of Armenian science journalists are presented. Scientific journalism in the world, forms of its activities, Armenian Astronomical Society (ArAS) press-releases and their subjects, ArAS website "Mass Media News" section, annual and monthly calendars of astronomical events, and "Astghagitak" online journal are described. Most interesting astronomical subjects involved in scientific journalism, reasons for non-satisfactory science outreach and possible solutions are discussed.

  2. Tips for Organizing an Educational Agricultural Commodity Trading Club

    ERIC Educational Resources Information Center

    Yost, John

    2011-01-01

    Educational commodity marketing clubs have been an effective tool for producers to develop their grain and livestock marketing skills. These groups are further enhanced when the participants engage in "actual trading" versus "paper trading" techniques. When a club chooses to try actual trading, it becomes more complicated than pooling monies…

  3. 11. Photocopy of Photograph (Courtesy of the Detroit Hockey Club, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photocopy of Photograph (Courtesy of the Detroit Hockey Club, Detroit, Michigan). GROUNDBREAKING FOR ADDITION, JUNE 23, 1965. Left Sid Abel, Genral Manager of the Detroit Hockey Club Center - Jerome Cavanaugh, Mayor, City of Detroit Right - Nick Landis, General Manager of the Olympia Stadium - Olympia Arena, 5920 Grand River Avenue, Detroit, MI

  4. School Nurse Book Clubs: An Innovative Strategy for Lifelong Learning

    ERIC Educational Resources Information Center

    Greenawald, Deborah A.; Adams, Theresa M.

    2008-01-01

    Recognizing the ongoing need for continuing education for school nurses, the authors discuss the use of school nurse book clubs as an innovative lifelong-learning strategy. Current research supports the use of literature in nursing education. This article discusses the benefits of book club participation for school nurses and includes suggested…

  5. Learning Masculinities in a Japanese High School Rugby Club

    ERIC Educational Resources Information Center

    Light, Richard

    2008-01-01

    This paper draws on research conducted on a Tokyo high school rugby club to explore diversity in the masculinities formed through membership in the club. Based on the premise that particular forms of masculinity are expressed and learnt through ways of playing (game style) and the attendant regimes of training, it examines the expression and…

  6. The Oprah Revolution: Book Clubs in Library Media Centers

    ERIC Educational Resources Information Center

    Littlejohn, Carol

    2006-01-01

    When Oprah Winfrey began her successful book club in 1996, she continued a tradition that public libraries have provided for decades. Oprah placed a spotlight on reading that encouraged many women who had never read a book "to read." Book clubs sprang up in neighborhoods, bookstores, and on Web sites. Library media centers began offering book…

  7. The "Oprahfication" of Literacy: Reading "Oprah's Book Club."

    ERIC Educational Resources Information Center

    Hall, R. Mark

    2003-01-01

    Considers how although the influence of "Oprah's Book Club" has been well documented in the popular media, it has received little attention from the academic community. Examines the club as a literacy delivery system, asking how literacy takes its shape from the interests of both Winfrey and her readers. (SG)

  8. Club drugs: coming to a patient near you.

    PubMed

    Talbert, Jeananne Johnson

    2014-03-13

    Club drugs have become increasingly popular with young adults and adolescents. Although users report similar effects of these drugs, they are pharmacologically and physiologically different. Understanding these differences and recognizing trends and effects of club drugs is essential for nurse practitioners. PMID:24481485

  9. Read Across Texas! 2002 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Edgmon, Missy; Ferate-Soto, Paolo; Foley, Lelana; Hager, Tina; Heard, Adriana; Ingham, Donna; Lopez, Nohemi; McMahon, Dorothy; Meyer, Sally; Parrish, Leila; Rodriguez-Gibbs, Josefina; Moreyra-Torres, Maricela; Travis, Gayle; Welch, Willy

    The goal of the Texas Reading Club is to encourage the children of Texas to become library users and lifelong readers. This manual was created for the 2002 Texas Reading Club, a program of the Texas State Library and Archives Commission. The theme, "Read Across Texas!" invites children to explore the history, geography, and culture of Texas…

  10. View of the yacht club facing north. The beach is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the yacht club facing north. The beach is in the foreground, the pier to the right. The painted octagonal window is above the deck. Avila's Front Street is at the rear of the building. - San Luis Yacht Club, Avila Pier, South of Front Street, Avila Beach, San Luis Obispo County, CA

  11. View of the yacht club from avila pier, facing west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the yacht club from avila pier, facing west northwest. The main entry is to the right and the more recent deck addition is to the left. - San Luis Yacht Club, Avila Pier, South of Front Street, Avila Beach, San Luis Obispo County, CA

  12. View of the yacht club facing east. The new deck ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the yacht club facing east. The new deck and the avila pier are on the right and the harbor storage and restrooms are on the left. - San Luis Yacht Club, Avila Pier, South of Front Street, Avila Beach, San Luis Obispo County, CA

  13. Online Book Clubs: Bridges between Old and New Literacies Practices

    ERIC Educational Resources Information Center

    Scharber, Cassandra

    2009-01-01

    In this Digital Literacies column, online book clubs are offered as one example of how to effectively bridge old and new literacy practices. These Internet-based book clubs capitalize on children's interest in new literacy practices while complementing, and hopefully encouraging, traditional reading practices. Examples from online book clubs…

  14. Contextual view to northnorthwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to north-northwest of Burton Park Club House and Amphitheater (90 mm lens). View taken from top of steps visible in previous photo. - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  15. Interior, main room , Burton Park Club House, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior, main room , Burton Park Club House, view to south from north end door (90mm lens). Front doors visible at left, fireplace at right, while kingpost trusses supports the roof. - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  16. Contextual view to northwest of Burton Park Club House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view to northwest of Burton Park Club House and Amphitheater. Gable-roofed building at right is barn housing maintenance equipment for the park. Adobe wall with pilasters forms backdrop for amphitheater stage (135mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  17. Interior, main room, Burton Park Club House, view to north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior, main room, Burton Park Club House, view to north (90mm lens). Fireplace at left, kitchen and restroom are through open doorway visible at right side of opposite end wall. - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  18. Stalemate: Girls and a Mixed-Gender Chess Club.

    ERIC Educational Resources Information Center

    Galitis, Ingrid

    2002-01-01

    Observed and conducted discussions with female members of an elementary-level, mixed-gender, Australian chess club to investigate why girls left and boys came to dominate the club. Results indicated that both home values and schooling transmitted and reinforced inequalities between the sexes, though in more subtle and less overt forms than in the…

  19. The Sierra Club--A History. Part 1: Origins & Outings

    ERIC Educational Resources Information Center

    Strong, Douglas H.

    1977-01-01

    This article discusses the early beginnings of the Sierra Club, nearly 100 years ago, and the leadership of John Muir and his contemporaries. Turn of the century photographs show campers and hikers on organized club outing designed to introduce people to mountain wilderness and its preservation. (MA)

  20. Registration of “Cara” soft white winter club wheat

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Club wheat (Triticium aestivum ssp. compactum) is an important component of the export grain market for the Pacific Northwest. Our objective was to develop a club wheat cultivar with resistance to stripe rust (Puccinia striiformis, f. sp. tritici Westend) and strawbreaker foot rot Oculimacula yallu...

  1. Handwriting Club: Using Sensory Integration Strategies To Improve Handwriting.

    ERIC Educational Resources Information Center

    Keller, Melissa

    2001-01-01

    This article describes all the steps and materials necessary to organize and conduct a handwriting club that provides direct instruction in handwriting combined with sensory integration activities. Typical club session format, sample activities, the promotion of social skills, handwriting strategies, and external stimulants are discussed.…

  2. A Framework for Facilitating Productive Discussions in Video Clubs

    ERIC Educational Resources Information Center

    van Es, Elizabeth A.

    2010-01-01

    Video has become a popular tool for professional development. Yet, little is known about how to design video-based learning environments that are productive for teacher learning. The author has used video for teacher learning in the context of a video club. In video clubs, teachers meet together on a regular basis to view and discuss video…

  3. Simplicity, Harmony Essential to Club of Rome Goals.

    ERIC Educational Resources Information Center

    Lepkowski, Wil

    1979-01-01

    This interview with Aurelio Peccei details the next phase in the Club of Rome's goal of reeducating mankind to global threats. Peccei discusses a variety of topics relating to science and the human condition, including his plans for the implementation of the Club of Rome activities. (BT)

  4. Teaching for Geographic Literacy: Our Afterschool Geography Club

    ERIC Educational Resources Information Center

    Thomas-Brown, Karen A.

    2011-01-01

    This research describes how enrolling students in an afterschool Geography Club affects their perception of the discipline and their geographic literacy. The creation of the afterschool club at this particular school came out of the recognition of the need to increase students' exposure to geographical content. The results of this study show the…

  5. Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.

    PubMed

    Bommineni, Gopal R; Kapilashrami, Kanishk; Cummings, Jason E; Lu, Yang; Knudson, Susan E; Gu, Chendi; Walker, Stephen G; Slayden, Richard A; Tonge, Peter J

    2016-06-01

    β-Ketoacyl-ACP synthases (KAS) are key enzymes involved in the type II bacterial fatty acid biosynthesis (FASII) pathway and are putative targets for antibacterial discovery. Several natural product KAS inhibitors have previously been reported, including thiolactomycin (TLM), which is produced by Nocardia spp. Here we describe the synthesis and characterization of optically pure 5R-thiolactomycin (TLM) analogues that show improved whole cell activity against bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) and priority pathogens such as Francisella tularensis and Burkholderia pseudomallei. In addition, we identify TLM analogues with in vivo efficacy against MRSA and Klebsiella pneumoniae in animal models of infection. PMID:27187871

  6. Arthropathy, ankylosing spondylitis, and clubbing of fingers in ulcerative colitis

    PubMed Central

    Jalan, K. N.; Prescott, R. J.; Walker, R. J.; Sircus, W.; McManus, J. P. A.; Card, W. I.

    1970-01-01

    In a retrospective study of 399 patients with ulcerative colitis, 27 patients had colitic arthritis, 17 had ankylosing spondylitis, and 20 had clubbing of the fingers. Colitic arthritis and ankylosing spondylitis were not related to severity, extent of involvement, or duration of colitis. A significant association between colitic arthropathy and other complications of ulcerative colitis, such as pseudopolyposis, perianal disease, eye lesions, skin eruptions, aphthous ulceration, and liver disease has been demonstrated. The outcome of the first referred attack of colitis in the presence of colitic arthritis and ankylosing spondylitis remained uninfluenced. Clubbing of fingers was related to severity, extent of involvement, and length of the history of colitis. A significant association between clubbing of the fingers and carcinoma of the colon, pseudopolyposis, toxic dilatation, and arthropathy has been shown. The frequency of surgical intervention in patients with clubbing was higher but the overall mortality was not significantly different from the patients without clubbing. PMID:5473606

  7. Medical marijuana: Federal, State attacks against California cannabis clubs.

    PubMed

    Gardner, F; James, J S

    1998-01-23

    The Clinton administration filed suit to close six marijuana buyers' clubs in California more than a year after Proposition 215, permitting medical use of the drug, was passed. This action was taken against six clubs: Cannabis Cultivators Club, Flower Therapy, Marin Alliance for Medical Marijuana, Oakland Cannabis Buyers' Cooperative, Santa Cruz Buyers' Club, and Ukiah Buyers' Club. Although Proposition 215 gives persons with a documented need for the drug a legal right to use it in California, the Federal prohibitions for its use still violates Federal law. In practice, social users can usually obtain marijuana while many patients who need it have no source from which to buy it. The history of the Federal attack on medical marijuana usage in California and the State's response are included. PMID:11365003

  8. Short-term storage of canine preantral ovarian follicles using a powdered coconut water (ACP)-based medium.

    PubMed

    Lima, G L; Costa, L L M; Cavalcanti, D M L P; Rodrigues, C M F; Freire, F A M; Fontenele-Neto, J D; Silva, A R

    2010-07-01

    The objective was to investigate the use of powdered coconut water (ACP)-based medium for short-term preservation of canine preantral follicles. Pairs of ovaries from mongrel bitches (n=9) were divided into fragments. One ovarian fragment, treated as a fresh control, was immediately fixed for histological analysis, whereas the other six ovarian fragments were stored either in phosphate-buffered saline (PBS; control group) or ACP medium in isothermal Styrofoam boxes containing biological ice packs. The boxes were sealed and opened only after 12, 24, or 36h. After opening each box, the ovarian fragments were submitted to histological analysis. In total, 12,302 preantral follicles were evaluated, with 64.5% primordial, 33.3% primary, and 2.3% secondary follicles. There were multiple oocytes in 1.3% of the follicles analyzed. At 24h, ACP was more efficient in preserving follicular morphology than PBS (P<0.05). Compared with the fresh control group, a significant reduction in the percentage of morphologically normal ovarian follicles was observed for PBS, starting at 24h; however, the decline started only at 36h for the ACP medium. During the experiment, the temperature inside the isothermal boxes increased from 3 to 9 degrees C (P<0.05), despite a constant room temperature. In conclusion, powdered coconut water (ACP) was an appropriate medium for short-term storage of canine preantral ovarian follicles. PMID:20207405

  9. Acyl-ACP thioesterases from Camelina sativa: cloning, enzymatic characterization and implication in seed oil fatty acid composition.

    PubMed

    Rodríguez-Rodríguez, Manuel Fernando; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2014-11-01

    Acyl-acyl carrier protein (ACP) thioesterases are intraplastidial enzymes that terminate de novo fatty acid biosynthesis in the plastids of higher plants by hydrolyzing the thioester bond between ACP and the fatty acid synthesized. Free fatty acids are then esterified with coenzyme A prior to being incorporated into the glycerolipids synthesized through the eukaryotic pathway. Acyl-ACP thioesterases belong to the TE14 family of thioester-active enzymes and can be classified as FatAs and FatBs, which differ in their amino acid sequence and substrate specificity. Here, the FatA and FatB thioesterases from Camelina sativa seeds, a crop of interest in plant biotechnology, were cloned, sequenced and characterized. The mature proteins encoded by these genes were characterized biochemically after they were heterologously expressed in Escherichia coli and purified. C. sativa contained three different alleles of both the FatA and FatB genes. These genes were expressed most strongly in expanding tissues in which lipids are very actively synthesized, such as developing seed endosperm. The CsFatA enzyme displayed high catalytic efficiency on oleoyl-ACP and CsFatB acted efficiently on palmitoyl-ACP. The contribution of these two enzymes to the synthesis of C. sativa oil was discussed in the light of these results. PMID:25212866

  10. Club Drug Use among Young Adults Frequenting Dance Clubs and Other Social Venues in New York City

    ERIC Educational Resources Information Center

    Parsons, Jeffrey T.; Halkitis, Perry N.; Bimbi, David S.

    2006-01-01

    A convenience sample of young adults (ages 18-25) in New York City was recruited to complete anonymous surveys in social venues (either dance clubs or other social settings, such as coffee shops and university "hangouts") regarding their use of "club drugs" (e.g., MDMA/Ecstasy, GHB, ketamine, crystal methamphetamine, cocaine, and LSD).…

  11. Why Children Join and Stay in Sports Clubs: Case Studies in Australian, French and German Swimming Clubs

    ERIC Educational Resources Information Center

    Light, Richard L.; Harvey, Stephen; Memmert, Daniel

    2013-01-01

    This article builds upon research on youth sport clubs conducted from a socio-cultural perspective by reporting on a study that inquired into the reasons why children aged 9-12 joined swimming clubs in France, Germany and Australia. Comprising three case studies it employed a mixed method approach with results considered within the framework of…

  12. Box Cello Middle School Science Clubs

    NASA Astrophysics Data System (ADS)

    Vandegrift, Guy

    1998-10-01

    The Box Cello is a middle school science club which is attempting to (1) understand the cello and (2) design a low-cost starter instrument. We can support and justify this research by adding a third goal: (3) to help supply local science classes with equipment. My policy of spending one entire day each week away from the university, out in a local school is essential to this project. This schedule also permits me to conduct lessons on optics and music in the schools. And, it permits circulation of tools and equipment. A simple calculation demonstrates the great economy achieved by combining science clubs with academic year school visits. Consider the cost of letting 10,000 students in 10 middle schools each learn about and play with a pair of "upside-down" glasses for one hour. A visit to each school for three consecutive weeks would easily permit such a circulation if only 30 pairs were constructed. Assume rhetorically, that the construction of 30 pairs of glasses were to consume the entire estimated annual budget of $100,000. The cost per student would be only ten dollars! The visits, guest lectures, and equipment loans permit informal networking (including lunch) with math, science and music teachers in 10 schools. For more information, visit the http://www.utep.edu/boxcello/

  13. The β-ketoacyl-ACP synthase from Mycobacterium tuberculosis as potential drug targets.

    PubMed

    Singh, V; Mani, I; Chaudhary, D K; Somvanshi, P

    2011-01-01

    The continuous preventive measures and control of tuberculosis are often hampered by re-emergence of multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis. A novel drug approach is desperately needed to combat the global threat posed by MDR strains. In spite of current advancement in biological techniques viz. microarray and proteomics data for tuberculosis, no such potent drug has been developed in the past decades yet. Therefore, mycolic acid is an essential constituent which is involved in the formation of cell wall of Mycobacterium species. The biosynthesis of mycolic acid is involved in two fatty acid synthase systems, the multifunctional polypeptide fatty acid synthase I (FASI) which performs de novo fatty acid synthesis and dissociate FASII system. FASII system consists of monofunctional enzymes and acyl carrier protein (ACP), elongating FASI products to long chain mycolic acid precursor. In this review, the β-ketoacyl-ACP synthases (fadH, kasA and kasB) are distinct and play a vital role in mycolic acid synthesis, cell wall synthesis, biofilm formation and also pathogenesis. On the basis of substantial observation we suggest that these enzymes may be used as promising and attractive targets for novel anti-TB drugs designing and discovery. PMID:21370994

  14. How to Rank Journals

    PubMed Central

    Bradshaw, Corey J. A.; Brook, Barry W.

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68–0.84 Spearman’s ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows. PMID:26930052

  15. How to Rank Journals.

    PubMed

    Bradshaw, Corey J A; Brook, Barry W

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68-0.84 Spearman's ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows. PMID:26930052

  16. 76 FR 37007 - Safety Zone; Stockton Ports Baseball Club Fourth of July Fireworks Display, Stockton, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Stockton Ports Baseball Club Fourth of July... Stockton Ports Baseball Club will sponsor the Stockton Ports Baseball Club Fourth of July Fireworks Display... read as follows: Sec. 165.T11-422 Safety Zone; Stockton Ports Baseball Club Fourth of July...

  17. Professional Development Through The University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    McGraw, Allison M.; Nieberding, Megan N.; Austin, Carmen; Hardegree-Ullman, Kevin

    2015-01-01

    The University of Arizona Astronomy Club creates a unique environment for undergraduates to accomplish goals early in their academic career. The club provides research opportunities with advisors, graduate students, and projects organized by fellow undergraduates. Undergraduates that work side-by-side develop strong working relationships which keeps students interested in astronomy and enables them to thrive in their studies and research. Club members are encouraged to attend and present their research at professional conferences where they are exposed early to the scientific research community, learn about internship and REU opportunities, and get information about graduate programs. In addition to preparing undergraduates to thrive in their academic career, the club also offers outreach opportunities for members to actively educate the southern Arizona community. Members of the club design and create many of their outreach materials including 3D models of our local stellar neighborhood and astronomical objects. Astronomy Club has had a positive impact on its members, the Department of Astronomy, and the southern Arizona community for the past seven years. The club continues to strive to improve undergraduate retention and prepare students for their future careers.

  18. Promoting undergraduate involvement through the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    McGraw, Allison M.; Austin, Carmen; Noyes, Matthew; Calahan, Jenny; Lautenbach, Jennifer; Henrici, Andrew; Ryleigh Fitzpatrick, M.; Shirley, Yancy L.

    2016-01-01

    The University of Arizona Astronomy Club is devoted to undergraduate success in astronomy, physics, planetary sciences and many other related fields. The club promotes many undergraduate opportunities; research projects, participating in telescope observational runs, sponsoring conference attendance as well as several public outreach opportunities. Research projects involving exoplanet transit observations and radio observations of cold molecular clouds allow undergraduates to experience data collection, telescope operations, data reduction and research presentation. The club hosts many star parties and various other public outreach events for the Tucson, Arizona location. The club often constructs their own outreach materials and structures. The club is currently working on creating a portable planetarium to teach about the night sky on the go even on the cloudiest of nights. The club is also working on creating a binocular telescope with two 10" mirrors as a recreation of the local Large Binocular Telescope for outreach purposes as well. This is a club that strives for undergraduate activity and involvement in a range of academic and extracurricular activates, and is welcoming to all majors of all levels in hopes to spark astronomical interest.

  19. Rich Club Organization and Cognitive Performance in Healthy Older Participants.

    PubMed

    Baggio, Hugo C; Segura, Barbara; Junque, Carme; de Reus, Marcel A; Sala-Llonch, Roser; Van den Heuvel, Martijn P

    2015-09-01

    The human brain is a complex network that has been noted to contain a group of densely interconnected hub regions. With a putative "rich club" of hubs hypothesized to play a central role in global integrative brain functioning, we assessed whether hub and rich club organizations are associated with cognitive performance in healthy participants and whether the rich club might be differentially involved in cognitive functions with a heavier dependence on global integration. A group of 30 relatively older participants (range = 39-79 years of age) underwent extensive neuropsychological testing, combined with diffusion-weighted magnetic resonance imaging to reconstruct individual structural brain networks. Rich club connectivity was found to be associated with general cognitive performance. More specifically, assessing the relationship between the rich club and performance in two specific cognitive domains, we found rich club connectivity to be differentially associated with attention/executive functions-known to rely on the integration of distributed brain areas-rather than with visuospatial/visuoperceptual functions, which have a more constrained neuroanatomical substrate. Our findings thus provide first empirical evidence of a relevant role played by the rich club in cognitive processes. PMID:25941870

  20. Using Science to Take a Stand: Action-Oriented Learning in an Afterschool Science Club

    NASA Astrophysics Data System (ADS)

    Hagenah, Sara

    This dissertation study investigates what happens when students participate in an afterschool science club designed around action-oriented science instruction, a set of curriculum design principles based on social justice pedagogy. Comprised of three manuscripts written for journal publication, the dissertation includes 1) Negotiating community-based action-oriented science teaching and learning: Articulating curriculum design principles, 2) Middle school girls' socio-scientific participation pathways in an afterschool science club, and 3) Laughing and learning together: Productive science learning spaces for middle school girls. By investigating how action-oriented science design principles get negotiated, female identity development in and with science, and the role of everyday social interactions as students do productive science, this research fills gaps in the understanding of how social justice pedagogy gets enacted and negotiated among multiple stakeholders including students, teachers, and community members along what identity development looks like across social and scientific activity. This study will be of interest to educators thinking about how to enact social justice pedagogy in science learning spaces and those interested in identity development in science.

  1. Women's Clubs as Educative Agencies: Wilmington, Delaware New Century Club, 1889-1920

    ERIC Educational Resources Information Center

    Taggart, Robert

    2006-01-01

    There is no doubt that women had a role in progressive reform a century ago, despite their lack of vote. However, it may not be so clear what the nature of this reform effort was. This article suggests that women were highly organized in women's clubs that served as a major organ of change in society, and that they had a great impact on education…

  2. Essayists, essays, and hosts: Daniel Hale Williams Medical Reading Club.

    PubMed Central

    Greene Reed, T.; Evans, C. C.

    1996-01-01

    The 66-year-old Daniel Hale Williams Medical Reading Club is an independent reading club comprised of 65 physicians in the metropolitan Washington, DC, area. Members representing all specialty fields meet six times a year for dinner and fellowship, to consider topics of common interest to the profession, and to hear a prepared lecture given by a featured essayist. Club members take turns as hosts for each meeting. This article gives a historical list of these meetings, naming the essayist and the topic, the hosts, and the site of the meetings. PMID:8918074

  3. Chaplain Documentation and the Electronic Medical Record: A Survey of ACPE Residency Programs.

    PubMed

    Tartaglia, Alexander; Dodd-McCue, Diane; Ford, Timothy; Demm, Charles; Hassell, Alma

    2016-01-01

    This study explores the extent to which chaplaincy departments at ACPE-accredited residency programs make use of the electronic medical record (EMR) for documentation and training. Survey data solicited from 219 programs with a 45% response rate and interview findings from 11 centers demonstrate a high level of usage of the EMR as well as an expectation that CPE residents document each patient/family encounter. Centers provided considerable initial training, but less ongoing monitoring of chaplain documentation. Centers used multiple sources to develop documentation tools for the EMR. One center was verified as having created the spiritual assessment component of the documentation tool from a peer reviewed published model. Interviews found intermittent use of the student chart notes for educational purposes. One center verified a structured manner of monitoring chart notes as a performance improvement activity. Findings suggested potential for the development of a standard documentation tool for chaplain charting and training. PMID:26168408

  4. A Project Management Approach to an ACPE Accreditation Self-study

    PubMed Central

    Iwanowicz, Susan L.; Bailie, George R.; Clarke, David W.; McGraw, Patrick S.

    2007-01-01

    In preparation for an on-site evaluation and accreditation by the American Council on Pharmaceutical Education (ACPE), the Albany College of Pharmacy employed project management techniques to complete a comprehensive self-study. A project lifecycle approach, including planning, production, and turnover phases, was used by the project's Self-Study Steering Committee. This approach, with minimal disruption to college operations, resulted in the completion of the self-study process on schedule. Throughout the project, the Steering Committee maintained a log of functions that either were executed successfully or in hindsight, could have been improved. To assess the effectiveness of the project management approach to the the self-study process, feedback was obtained from the College community through a poststudy survey. This feedback, coupled with the Steering Committee's data on possible improvements, form the basis for the lessons learned during this self-study process. PMID:17533432

  5. 12. Historic American Buildings Survey Topographic Survey of Cosmos Club, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey Topographic Survey of Cosmos Club, 1950, by Bernard Locroft, Civil Engineer (Showing Grounds as They Were at End of Sumner Welles Era) SITE PLAN - Townsend House, 2121 Massachusetts Avenue Northwest, Washington, District of Columbia, DC

  6. 4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING COILS AND CORK-LINED ROOM. CAMERA IS BETWEEN SEVEN AND EIGHT FEET ABOVE FLOOR LEVEL, FACING SOUTHEAST. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  7. Leading the Fit Life: Jobs in Health Clubs.

    ERIC Educational Resources Information Center

    Green, Kathleen

    1995-01-01

    Depicts the health club work force: fitness personnel, such as instructors, trainers, and directors, and nonfitness personnel, such as receptionists, marketers, and managers, as well as physicians and therapists. Gives information on how to acquire credentials in the field. (SK)

  8. Encouraging a Culture of Outreach in Astronomy Clubs

    NASA Astrophysics Data System (ADS)

    Manning, J.; Berendsen, M.; Schultz, G.; Gurton, S.; Santascoy, J.; White, V.; Frank, K.; Jones, E.; Yocco, V.; John, M. S.; Castori, P.

    2014-07-01

    Astronomy clubs constitute a “marching army” of knowledgeable, experienced astronomy enthusiasts deployed in a national network: an important resource for engaging the public through educational outreach events and activities. The Astronomical Society of the Pacific (ASP) in partnership with the Institute for Learning Innovation (ILI) and Inverness Research, Inc., has been engaged in a multi-year NSF-supported project focusing on this network and its potential to advance astronomy education and outreach. The project has explored the culture of astronomy clubs, identified impediments to building cultures of outreach within clubs, and developed and introduced new mechanisms to overcome these impediments and enhance clubs' abilities to encourage and sustain cultures that value and promote outreach efforts. This paper shares initial research, development and evaluation findings of the project, and describes ongoing supplemental efforts that continue to advance project objectives.

  9. Seeing the Forest for the Trees. Penn State Faculty Club

    ERIC Educational Resources Information Center

    Progressive Architecture, 1977

    1977-01-01

    The new faculty club at Pennsylvania State University designed by Venturi and Rauch, is praised for its siting, but criticized for the institutional colors of the interior and lack of accommodation to human needs. (MLF)

  10. 7. CLUBHOUSE. FIREPLACE IN CLUB ROOM. VIEW TO NORTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. CLUBHOUSE. FIREPLACE IN CLUB ROOM. VIEW TO NORTHWEST. - Rainbow Hydroelectric Facility, Clubhouse, On north bank of Missouri River 2 miles Northeast of Great Falls, & end of Rainbow Dam Road, Great Falls, Cascade County, MT

  11. Evaluation of the remineralization capacity of CPP-ACP containing fluoride varnish by different quantitative methods

    PubMed Central

    SAVAS, Selcuk; KAVRÌK, Fevzi; KUCUKYÌLMAZ, Ebru

    2016-01-01

    ABSTRACT Objective The aim of this study was to evaluate the efficacy of CPP-ACP containing fluoride varnish for remineralizing white spot lesions (WSLs) with four different quantitative methods. Material and Methods Four windows (3x3 mm) were created on the enamel surfaces of bovine incisor teeth. A control window was covered with nail varnish, and WSLs were created on the other windows (after demineralization, first week and fourth week) in acidified gel system. The test material (MI Varnish) was applied on the demineralized areas, and the treated enamel samples were stored in artificial saliva. At the fourth week, the enamel surfaces were tested by surface microhardness (SMH), quantitative light-induced fluorescence-digital (QLF-D), energy-dispersive spectroscopy (EDS) and laser fluorescence (LF pen). The data were statistically analyzed (α=0.05). Results While the LF pen measurements showed significant differences at baseline, after demineralization, and after the one-week remineralization period (p<0.05), the difference between the 1- and 4-week was not significant (p>0.05). With regards to the SMH and QLF-D analyses, statistically significant differences were found among all the phases (p<0.05). After the 1- and 4-week treatment periods, the calcium (Ca) and phosphate (P) concentrations and Ca/P ratio were higher compared to those of the demineralization surfaces (p<0.05). Conclusion CPP-ACP containing fluoride varnish provides remineralization of WSLs after a single application and seems suitable for clinical use. PMID:27383699

  12. Rhamnolipid and poly (hydrozyalkanoate) biosynthesis in 3-hydrozyacyl-ACP:COA transacylase (phaG) - knockouts of pseudomonas chloroaphis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 3-hydroxyacyl-ACP:CoA transacylase gene (phaG(Pc30761)) of P. chlororaphis NRRL B-30761 was cloned and analyzed. The nucleotide and translated amino-acid sequences of phaG(Pc30761) had 99% identities (at 100% query coverage) with the phaG gene of P. fluorescens O6. Two phaG-knockout strains of...

  13. Design and Synthesis of 2-Pyridones as Novel Inhibitors of the Bacillus Anthracis Enoyl–ACP Reductase

    PubMed Central

    Tipparaju, Suresh K.; Joyasawal, Sipak; Forrester, Sara; Mulhearn, Debbie C.; Pegan, Scott; Johnson, Michael E.; Mesecar, Andrew D.; Kozikowski, Alan P.

    2008-01-01

    Enoyl-ACP reductase (ENR), the product of the FabI gene, from Bacillus anthracis (BaENR) is responsible for catalyzing the final step of bacterial fatty acid biosynthesis. A number of novel 2-pyridone derivatives were synthesized and shown to be potent inhibitors of BaENR. PMID:18499454

  14. R&W Club Frederick Sews for Kids | Poster

    Cancer.gov

    By Carolynne Keenan, Contributing Writer Sewing enthusiasts of all skill levels are invited to attend a sewing party hosted by the R&W Club Frederick on Feb. 18. Stop by the Building 549 Café Room between 10 a.m. and 4 p.m. to sew for a cause: help the club make pillowcases for ConKerr Cancer, a nonprofit organization that supports children in hospitals across the country.

  15. The Journal Book.

    ERIC Educational Resources Information Center

    Fulwiler, Toby, Ed.

    Essays on the use of journal writing in the classroom are presented in four sections: the language of speculation, journals in the teaching of English, the arts and humanities, and the quantitative disciplines. Titles and authors are as follows: (1) "Dialectical Notebooks and the Audit of Meaning" (A. E. Berthoff); (2) "Desert Island Discourse:…

  16. Journals of Discovery

    ERIC Educational Resources Information Center

    Livingston, Cathy

    2005-01-01

    In this article, the author shares her experiences with science journaling, and finds it a valuable resource in discovering how well students have grasped the concepts of each lesson. The journal has also been a valuable tool in helping students to evaluate themselves, and write their comments on their own strengths and "weaknesses" or areas of…

  17. Rewriting the Journal

    ERIC Educational Resources Information Center

    Fredette, Michelle

    2012-01-01

    With faculty balking at the price of academic journals, can other digital publishing options get traction? University libraries are no strangers to one of the most popular online alternatives, the open-access archive. These archives enable scholars to upload work--including drafts of articles that are published later in subscription journals--so…

  18. Journals and Program Assessment

    ERIC Educational Resources Information Center

    Cluphf, David J.; Lox, Curt L.

    2009-01-01

    The purpose of this study was to use journal feedback from student teachers to understand and document how well the Physical Education-Teacher Education (PETE) program prepares teacher candidates in relation to the three primary goals of the PETE program. Analysis of the journals revealed areas of merit and concern for the PETE faculty. The most…

  19. Istrazivacko novinarstvo (Investigative Journalism).

    ERIC Educational Resources Information Center

    Kosir, Manca

    1995-01-01

    Reports that the democratization of the political system establishes a special type of reporting: the "so-called" investigative journalism. Defines the basic characteristics of this type of journalism--states that the journalist conducts the investigation very thoroughly, using special techniques/methods. Sees the journalist's role as "watchdog"…

  20. Adrenomedullin regulates club cell recovery following lung epithelial injury.

    PubMed

    García-Sanmartín, Josune; Larrayoz, Ignacio M; Martínez, Alfredo

    2016-06-01

    The equilibrium between lung epithelium damage and recovery in the context of chronic injury is at the basis of numerous lung diseases, including lung cancer and COPD. Understanding the contribution of growth factors and other molecular intermediates to this crosstalk may help in devising new therapeutic approaches. To better understand the contribution of adrenomedullin (AM) to lung homeostasis, we built club cell-specific conditional knockout (KO) mice for AM and subjected them to naphthalene injury. Untreated KO mice had lower levels of club cell 10 KDa protein (CC10) immunoreactivity than their wild type (WT) littermates in both terminal and regular bronchioles. Naphthalene injury resulted in a rapid necrosis of club cells followed by a progressive recovery of the epithelium. Club cells proliferated at higher rates in the KO mice and at 21 days post-injury the club cell coverage of the main bronchioles was higher and more homogeneous than in the WT animals. In conclusion, the paracrine/autocrine influence of AM in club cells subtly modulates their proliferation and spreading kinetics during lung epithelium recovery. PMID:26661726

  1. Microleakage of Three Types of Glass Ionomer Cement Restorations: Effect of CPP-ACP Paste Tooth Pretreatment

    PubMed Central

    Doozandeh, Maryam; Shafiei, Fereshteh; Alavi, Mostafa

    2015-01-01

    Statement of the Problem Casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) increases the mineral content of tooth structure. This may enhance the chemical bonding of glass ionomer cements (GIC) and marginal sealing of their restorations. Purpose The aim of this study was to evaluate the effect of CPP-ACP paste pretreatment on the microleakage of three types of GIC. Materials and Method In this study, 72 Class V cavities were prepared on the buccal and lingual surfaces of molars with occlusal margins in enamel and gingival margins in root. The cavities were divided into 6 groups. Cavities in group 1 and 2 were restored with Fuji II, group 3 and 4 with Fuji II LC, and group 5 and 6 with Ketac N100 with respect to the manufacturers’ instructions. In groups 2, 4 and 6, CPP-ACP containing paste (MI paste) was placed into the cavities for 3 minutes before being filled with GIC. The teeth were thermocycled, stained with dye, sectioned, and scored for microleakage under stereomicroscope. Kruskall-Wallis and Chi-Square tests were used to analyze the data. Result There were no statistically significant differences between the control and the CPP-ACP pretreatment groups in enamel and dentin margins. In pairwise comparisons, there were no significant differences between the control and the experimental groups in enamel margin, and in dentin margins of G1 and 2, G5 and 6; however, a significant differences was detected in dentin margins between G3 and 4 (p= 0.041). Conclusion CPP-ACP paste pretreatment did not affect the microleakage of Fuji II and Ketac N100 in enamel or dentin, but decreased the microleakage in dentine margins of Fuji II LC when cavity conditioner was applied before surface treatment. PMID:26331147

  2. The Acid Phosphatase-Encoding Gene GmACP1 Contributes to Soybean Tolerance to Low-Phosphorus Stress

    PubMed Central

    Hao, Derong; Wang, Hui; Kan, Guizhen; Jin, Hangxia; Yu, Deyue

    2014-01-01

    Phosphorus (P) is essential for all living cells and organisms, and low-P stress is a major factor constraining plant growth and yield worldwide. In plants, P efficiency is a complex quantitative trait involving multiple genes, and the mechanisms underlying P efficiency are largely unknown. Combining linkage analysis, genome-wide and candidate-gene association analyses, and plant transformation, we identified a soybean gene related to P efficiency, determined its favorable haplotypes and developed valuable functional markers. First, six major genomic regions associated with P efficiency were detected by performing genome-wide associations (GWAs) in various environments. A highly significant region located on chromosome 8, qPE8, was identified by both GWAs and linkage mapping and explained 41% of the phenotypic variation. Then, a regional mapping study was performed with 40 surrounding markers in 192 diverse soybean accessions. A strongly associated haplotype (P = 10−7) consisting of the markers Sat_233 and BARC-039899-07603 was identified, and qPE8 was located in a region of approximately 250 kb, which contained a candidate gene GmACP1 that encoded an acid phosphatase. GmACP1 overexpression in soybean hairy roots increased P efficiency by 11–20% relative to the control. A candidate-gene association analysis indicated that six natural GmACP1 polymorphisms explained 33% of the phenotypic variation. The favorable alleles and haplotypes of GmACP1 associated with increased transcript expression correlated with higher enzyme activity. The discovery of the optimal haplotype of GmACP1 will now enable the accurate selection of soybeans with higher P efficiencies and improve our understanding of the molecular mechanisms underlying P efficiency in plants. PMID:24391523

  3. Our Censored Journals

    PubMed Central

    Healy, David

    2008-01-01

    When an article is rejected by a medical journal, the standard assumption is that the article is unsound or there is something wrong with the author. Alternatively, it may have been because the journal editor was concerned about the consequences should the article be published. This article seeks to inform discussion by providing a series of instances in which editorial concerns about the consequences to journals may have counted for more than any assessment about the truth-value of the article or the motives of its authors. This claim is based on the fact that different journals may treat exactly the same article in an entirely different fashion; some issues appear to be taboo in certain journals, no matter who the author, and there is a series of explicit communications from editors that publication has been held up by their legal departments. PMID:22013362

  4. Journal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts.

    PubMed

    Rhodes, Deborah J; Hruska, Carrie B; Conners, Amy Lynn; Tortorelli, Cindy L; Maxwell, Robert W; Jones, Katie N; Toledano, Alicia Y; O'Connor, Michael K

    2015-02-01

    OBJECTIVE. The purpose of this study was to assess the diagnostic performance of supplemental screening molecular breast imaging (MBI) in women with mammographically dense breasts after system modifications to permit radiation dose reduction. SUBJECTS AND METHODS. A total of 1651 asymptomatic women with mammographically dense breasts on prior mammography underwent screening mammography and adjunct MBI performed with 300-MBq (99m)Tc-sestamibi and a direct-conversion (cadmium zinc telluride) gamma camera, both interpreted independently. The cancer detection rate, sensitivity, specificity, and positive predictive value of biopsies performed (PPV3) were determined. RESULTS. In 1585 participants with a complete reference standard, 21 were diagnosed with cancer: two detected by mammography only, 14 by MBI only, three by both modalities, and two by neither. Of 14 participants with cancers detected only by MBI, 11 had invasive disease (median size, 0.9 cm; range, 0.5-4.1 cm). Nine of 11 (82%) were node negative, and two had bilateral cancers. With the addition of MBI to mammography, the overall cancer detection rate (per 1000 screened) increased from 3.2 to 12.0 (p < 0.001) (supplemental yield 8.8). The invasive cancer detection rate increased from 1.9 to 8.8 (p < 0.001) (supplemental yield 6.9), a relative increase of 363%, while the change in DCIS detection was not statistically significant (from 1.3 to 3.2, p =0.250). For mammography alone, sensitivity was 24%; specificity, 89%; and PPV3, 25%. For the combination, sensitivity was 91% (p < 0.001); specificity, 83% (p < 0.001); and PPV3, 28% (p = 0.70). The recall rate increased from 11.0% with mammography alone to 17.6% (p < 0.001) for the combination; the biopsy rate increased from 1.3% for mammography alone to 4.2% (p < 0.001). CONCLUSION. When added to screening mammography, MBI performed using a radiopharmaceutical activity acceptable for screening (effective dose 2.4 mSv) yielded a supplemental cancer detection rate of 8.8 per 1000 women with mammographically dense breasts. PMID:25615744

  5. Teachers' Journal Club: Bridging between the Dynamics of Biological Discoveries and Biology Teachers

    ERIC Educational Resources Information Center

    Brill, Gilat; Falk, Hedda; Yarden, Anat

    2003-01-01

    Since biology is one of the most dynamic research fields within the natural sciences, the gap between the accumulated knowledge in biology and the knowledge that is taught in schools, increases rapidly with time. Our long-term objective is to develop means to bridge between the dynamics of biological discoveries and the biology teachers and…

  6. Integrated Literacies in a Rural Kenyan Girls' Secondary School Journalism Club

    ERIC Educational Resources Information Center

    Kendrick, Maureen; Early, Margaret; Chemjor, Walter

    2013-01-01

    Our purpose in this paper is to foreground contextual issues in studies of situated writing practices. During a year-long case study in a rural Kenyan secondary school, we applied a number of ethnographic techniques to document how 32 girls (aged 14-18 years) used local cultural and digital resources (i.e., donated digital cameras, voice…

  7. Biomimetic remineralization of demineralized dentine using scaffold of CMC/ACP nanocomplexes in an in vitro tooth model of deep caries.

    PubMed

    Chen, Zhen; Cao, Shansong; Wang, Haorong; Li, Yanqiu; Kishen, Anil; Deng, Xuliang; Yang, Xiaoping; Wang, Yinghui; Cong, Changhong; Wang, Huajun; Zhang, Xu

    2015-01-01

    Currently, it is still a tough task for dentists to remineralize dentine in deep caries. The aim of this study was to remineralize demineralized dentine in a tooth model of deep caries using nanocomplexes of carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) based on mimicking the stabilizing effect of dentine matrix protein 1 (DMP1) on ACP in the biomineralization of dentine. The experimental results indicate that CMC can stabilize ACP to form nanocomplexes of CMC/ACP, which is able to be processed into scaffolds by lyophilization. In the single-layer collagen model, ACP nanoparticles are released from scaffolds of CMC/ACP nanocomplexes dissolved and then infiltrate into collagen fibrils via the gap zones (40 nm) to accomplish intrafibrillar mineralization of collagen. With this method, the completely demineralized dentine was partially remineralized in the tooth mode. This is a bottom-up remineralizing strategy based on non-classical crystallization theory. Since nanocomplexes of CMC/ACP show a promising effect of remineralization on demineralized dentine via biomimetic strategy, thereby preserving dentinal tissue to the maximum extent possible, it would be a potential indirect pulp capping (IPC) material for the management of deep caries during vital pulp therapy based on the concept of minimally invasive dentistry (MID). PMID:25587986

  8. Biomimetic Remineralization of Demineralized Dentine Using Scaffold of CMC/ACP Nanocomplexes in an In Vitro Tooth Model of Deep Caries

    PubMed Central

    Chen, Zhen; Cao, Shansong; Wang, Haorong; Li, Yanqiu; Kishen, Anil; Deng, Xuliang; Yang, Xiaoping; Wang, Yinghui; Cong, Changhong; Wang, Huajun; Zhang, Xu

    2015-01-01

    Currently, it is still a tough task for dentists to remineralize dentine in deep caries. The aim of this study was to remineralize demineralized dentine in a tooth model of deep caries using nanocomplexes of carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) based on mimicking the stabilizing effect of dentine matrix protein 1 (DMP1) on ACP in the biomineralization of dentine. The experimental results indicate that CMC can stabilize ACP to form nanocomplexes of CMC/ACP, which is able to be processed into scaffolds by lyophilization. In the single-layer collagen model, ACP nanoparticles are released from scaffolds of CMC/ACP nanocomplexes dissolved and then infiltrate into collagen fibrils via the gap zones (40 nm) to accomplish intrafibrillar mineralization of collagen. With this method, the completely demineralized dentine was partially remineralized in the tooth mode. This is a bottom-up remineralizing strategy based on non-classical crystallization theory. Since nanocomplexes of CMC/ACP show a promising effect of remineralization on demineralized dentine via biomimetic strategy, thereby preserving dentinal tissue to the maximum extent possible, it would be a potential indirect pulp capping (IPC) material for the management of deep caries during vital pulp therapy based on the concept of minimally invasive dentistry (MID). PMID:25587986

  9. Overexpression of the olive acyl carrier protein gene (OeACP1) produces alterations in fatty acid composition of tobacco leaves.

    PubMed

    De Marchis, Francesca; Valeri, Maria Cristina; Pompa, Andrea; Bouveret, Emmanuelle; Alagna, Fiammetta; Grisan, Simone; Stanzione, Vitale; Mariotti, Roberto; Cultrera, Nicolò; Baldoni, Luciana; Bellucci, Michele

    2016-02-01

    Taking into account that fatty acid (FA) biosynthesis plays a crucial role in lipid accumulation in olive (Olea europaea L.) mesocarp, we investigated the effect of olive acyl carrier protein (ACP) on FA composition by overexpressing an olive ACP cDNA in tobacco plants. The OeACP1.1A cDNA was inserted in the nucleus or in the chloroplast DNA of different tobacco plants, resulting in extensive transcription of the transgenes. The transplastomic plants accumulated lower olive ACP levels in comparison to nuclear-transformed plants. Moreover, the phenotype of the former plants was characterized by pale green/white cotyledons with abnormal chloroplasts, delayed germination and reduced growth. We suggest that the transplastomic phenotype was likely caused by inefficient olive ACP mRNA translation in chloroplast stroma. Conversely, total lipids from leaves of nuclear transformants expressing high olive ACP levels showed a significant increase in oleic acid (18:1) and linolenic acid (18:3), and a concomitant significant reduction of hexadecadienoic acid (16:2) and hexadecatrienoic acid (16:3). This implies that in leaves of tobacco transformants, as likely in the mesocarp of olive fruit, olive ACP not only plays a general role in FA synthesis, but seems to be specifically involved in chain length regulation forwarding the elongation to C18 FAs and the subsequent desaturation to 18:1 and 18:3. PMID:26560313

  10. [Almaty club "KAIRAT" young football players' health].

    PubMed

    Kausova, G K; Karabaeva, A I

    2013-10-01

    The aim of the investigation was to study young football players' health. The study was conducted on 161 football players (mean age 12.3) of six children football teams of Almaty club "KAIRAT" during the competition period. It was found that 55,5% of the football players are practically healthy; 18,6% of football players have iron deficiency anemia. 32,6% of football players have caries; 5% of football players have problems of cardiopulmonary system. Investigation reveal, that in a junior sportsman was body weigh surging with downtrend during contest, testify to portability of aerobic load and in childhood unconformable of metabolism' level. This tendency was retain also in the oldest sportsman, this testify to most emulative aerobic load in comparison with junior sportsman. According as the age increases it is emulative load's extension and free occurrence of body weigh subsequent reduction but in the oldest sportsman with prevalence macrosomia. Concurrently with improvement of the anthropometric profile as far as increase of age in soccer players it is forming of a high training level. In spite of lowering of energy resources and the physical load organism's adaptation there are these phenomena. According as the age increases in a soccer player's performance of cardiac and respiratory system are improved. PMID:24214593

  11. The Cost of Journals

    NASA Astrophysics Data System (ADS)

    Moore, John W.

    1997-08-01

    On page 896 we announce appointment of a new Publications Coordinator for the Journal, Richard Schwenz of the University of Northern Colorado. After five years of yeoman service, Ken Emerson of Montana State University, is retiring. Ken has seen the Journal through a lot of change: a new editor, a new advertising representative, a new subscription fulfillment agent, and a consolidation of the Journal's print, software, and online operations. All this has taken a lot of work and intelligence, and the entire editorial staff thanks Ken for all of his efforts on our behalf.

  12. Solution Structure of 4′-Phosphopantetheine - GmACP3 from Geobacter metallireducens: A Specialized Acyl Carrier Protein with Atypical Structural Features and a Putative Role in Lipopolysaccharide Biosynthesis†

    PubMed Central

    Ramelot, Theresa A.; Smola, Matthew J.; Lee, Hsiau-Wei; Ciccosanti, Colleen; Hamilton, Keith; Acton, Thomas B.; Xiao, Rong; Everett, John K.; Prestegard, James H.; Montelione, Gaetano T.; Kennedy, Michael A.

    2011-01-01

    GmACP3 from Geobacter metallireducens is a specialized acyl carrier protein (ACP) whose gene, gmet_2339, is located near genes encoding many proteins involved in lipopolysaccharide (LPS) biosynthesis, indicating a likely function for GmACP3 in LPS production. By overexpression in Escherichia coli, about 50% holo-GmACP3 and 50% apo-GmACP3 were obtained. Apo-GmACP3 exhibited slow precipitation and non-monomeric behavior by 15N NMR relaxation measurements. Addition of 4′-phosphopantetheine (4′-PP) via enzymatic conversion by E. coli holo-ACP synthase, resulted in stable >95% holo-GmACP3 that was characterized as monomeric by 15N relaxation measurements and had no indication of conformational exchange. We have determined a high-resolution solution structure of holo-GmACP3 by standard NMR methods, including refinement with two sets of NH residual dipolar couplings, allowing for a detailed structural analysis of the interactions between 4′-PP and GmACP3. Whereas the overall four helix bundle topology is similar to previously solved ACP structures, this structure has unique characteristics, including an ordered 4′-PP conformation that places the thiol at the entrance to a central hydrophobic cavity near a conserved hydrogen-bonded Trp-His pair. These residues are part of a conserved WDSLxH/N motif found in GmACP3 and it’s orthologs. The helix locations and the large hydrophobic cavity are more similar to medium- and long-chain acyl-ACPs than to other apo- and holo-ACP structures. Taken together, structural characterization along with bioinformatic analysis of nearby genes suggest that GmACP3 is involved in lipid A acylation, possibly by atypical long-chain hydroxy fatty acids, and potentially involved in synthesis of secondary metabolites. PMID:21235239

  13. Epidemiological comparison of injuries in school and senior club rugby.

    PubMed Central

    Lee, A J; Garraway, W M

    1996-01-01

    OBJECTIVE: To determine the frequency, nature, circumstances, and outcome of schoolboy rugby injuries and to compare these injuries with those occurring in senior rugby clubs. METHODS: The study was a prospective cohort study, conducted on 1705 (98%) of 1736 eligible players from nine Edinburgh schools and 1169 (96%) of 1216 eligible players from all 26 senior Scottish Rugby Union clubs (South District) who provided personal details before the 1993-1994 rugby season. Adult linkpersons were appointed to notify the circumstances of all injury episodes occurring in matches or in rugby related training. RESULTS: 154 school players (9%) experienced 210 separate injuries in 186 injury episodes, 80% of which arose in matches. The prevalence rate of schoolboy match injuries was 86.8 (95% confidence interval 73.4 to 100.2) per 1000 player-seasons. Senior club match injury prevalence was much higher at 367.0 (339.4 to 394.6) per 1000 player-seasons. Club players had a higher rate of match injury than school-boys for all injury types. One third of schoolboy match injury episodes occurred in September and the majority of match injury episodes were associated with tackling (40%) or with being tackled (24%). Nine per cent of schoolboy match injury episodes were classified as severe, compared to 13% for clubs. Sixteen per cent (n = 23) of all schoolboy match injury episodes resulted in missed school attendance compared with 27% (n = 117) of all senior club match injury episodes which involved loss of employment or education. CONCLUSIONS: Schoolboy rugby is much safer than senior club rugby and the outcome of injuries that do occur is less disruptive. The relatively high rate of match injury in September migh be reduced by a more intensive period of preseason training. PMID:8889113

  14. Creating a Health Journal

    MedlinePlus

    ... doctor can also help you keep your health journal up-to-date. Keeping track of your health history helps you to be an informed, knowledgeable patient. Knowledge allows you to take more control of your ...

  15. In Other Professional Journals.

    ERIC Educational Resources Information Center

    Campbell, Christine M.

    1992-01-01

    Lists current articles, appearing in major journals on language teaching and learning, applied psycholinguistics, linguistics, curriculum development, computer science, psychology, educational technology, and general education, of particular interest to foreign language instruction professionals. (CB)

  16. Journaling: Astronauts Chronicle Missions

    NASA Video Gallery

    Journaling has and will always play an important role in any journey. It’s a simple yet invaluable tool used by behavioral scientists to help assess the mental and emotional states associated with ...

  17. Estimating Impact Forces of Tail Club Strikes by Ankylosaurid Dinosaurs

    PubMed Central

    Arbour, Victoria Megan

    2009-01-01

    Background It has been assumed that the unusual tail club of ankylosaurid dinosaurs was used actively as a weapon, but the biological feasibility of this behaviour has not been examined in detail. Ankylosaurid tail clubs are composed of interlocking vertebrae, which form the handle, and large terminal osteoderms, which form the knob. Methodology/Principal Findings Computed tomographic (CT) scans of several ankylosaurid tail clubs referred to Dyoplosaurus and Euoplocephalus, combined with measurements of free caudal vertebrae, provide information used to estimate the impact force of tail clubs of various sizes. Ankylosaurid tails are modeled as a series of segments for which mass, muscle cross-sectional area, torque, and angular acceleration are calculated. Free caudal vertebrae segments had limited vertical flexibility, but the tail could have swung through approximately 100° laterally. Muscle scars on the pelvis record the presence of a large M. longissimus caudae, and ossified tendons alongside the handle represent M. spinalis. CT scans showed that knob osteoderms were predominantly cancellous, which would have lowered the rotational inertia of the tail club and made it easier to wield as a weapon. Conclusions/Significance Large knobs could generate sufficient force to break bone during impacts, but average and small knobs could not. Tail swinging behaviour is feasible in ankylosaurids, but it remains unknown whether the tail was used for interspecific defense, intraspecific combat, or both. PMID:19707581

  18. School Astronomy Club: from Project to Knowledge

    NASA Astrophysics Data System (ADS)

    Folhas, Alvaro

    2016-04-01

    Prepare a generation of young people for the challenges of the future is a task which forces us to rethink the school, not just for being difficult, but also because students feel that the school has very little to offer, especially something that interests them. Thus, the school is dysfunctional, is ill, and needs prompt treatment. School have to adjust to the new times, and this does not mean changing the old blackboards by advanced interactive whiteboards. The school has to find the way to the students with something that seduce them: the Challenge. The Astronomy Club that I lead in my school is essentially a Project space. Students who voluntarily joined the club, organize themselves according to their interests around projects whose outcome is not defined from the beginning, which requires them to do, undo and redo. Which obliges them to feel the need to ask for help to mathematics or physics to achieve answers, to feel the passion to study with a genuine purpose of learning. Some examples of the work: The younger students are challenged to reproduce the historical astronomical experiments that have opened the doors of knowledge such as the Eratosthenes experiment to determine the perimeter of the Earth (on equinox), or by using congruent triangles, determine the diameter the sun. These students are driven to establish distance scales in the solar system, which, to their astonishment, allows them to clear misconceptions that arise from some pictures of books and allows them to have a scientifically correct idea of the planetary orbit and distance separating the planets of the Solar System. For students from 15 to 18 years, I have to raise the level of the challenges and use the natural tendency of this age bracket to assert making new and exciting things. To this purpose, I am fortunate to have the support of large organizations like NUCLIO, ESA, CERN, and Go-Lab Project, Inspiring Science Education, Open Discovery Space and Global Hands on Universe. Through

  19. East façade, Burton Park Club House, with Amphitheater in foreground, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East façade, Burton Park Club House, with Amphitheater in foreground, view to north from Amphitheater stage (90 mm lens). - Burton Park, Club House & Amphitheater, Adjacent ot south end of Chestnut Avenue, San Carlos, San Mateo County, CA

  20. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus

    DOE PAGESBeta

    Wang, Hui; Lu, Yang; Liu, Li; Kim, Sung Won; Hooker, Jacob M.; Fowler, Joanna S.; Tonge, Peter J.

    2014-09-06

    Here we evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of PT119, a potent Staphylococcus aureus enoyl-ACP reductase (saFabI) inhibitor with a Ki value of 0.01 nM and a residence time of 750 min on the enzyme target in mice. PT119 was found to have promising antibacterial activity in two different S. aureus infection models: it caused a 3 log reduction in the CFU’s in a mouse thigh muscle infection model and increased the survival rate from 0% to 50% in a mouse systemic infection model. PT119 was then radiolabeled with carbon-11 to evaluate its biodistribution and PK in both healthymore » and S. aureus infected mice using positron emission tomography (PET). The biodistribution of [11C]PT119 and/or its labeled metabolites did not differ significantly between the healthy group and the infected group, and PT119 was found to distribute equally between serum and tissue during the ~1 h of analysis permitted by the carbon-11 half life. This approach provides important data for PK/PD modeling and is the first step in identifying radiotracers that can non-invasively image bacterial infection in vivo.« less

  1. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus

    SciTech Connect

    Wang, Hui; Lu, Yang; Liu, Li; Kim, Sung Won; Hooker, Jacob M.; Fowler, Joanna S.; Tonge, Peter J.

    2014-09-06

    Here we evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of PT119, a potent Staphylococcus aureus enoyl-ACP reductase (saFabI) inhibitor with a Ki value of 0.01 nM and a residence time of 750 min on the enzyme target in mice. PT119 was found to have promising antibacterial activity in two different S. aureus infection models: it caused a 3 log reduction in the CFU’s in a mouse thigh muscle infection model and increased the survival rate from 0% to 50% in a mouse systemic infection model. PT119 was then radiolabeled with carbon-11 to evaluate its biodistribution and PK in both healthy and S. aureus infected mice using positron emission tomography (PET). The biodistribution of [11C]PT119 and/or its labeled metabolites did not differ significantly between the healthy group and the infected group, and PT119 was found to distribute equally between serum and tissue during the ~1 h of analysis permitted by the carbon-11 half life. This approach provides important data for PK/PD modeling and is the first step in identifying radiotracers that can non-invasively image bacterial infection in vivo.

  2. Citation Indicators of Japanese Journals.

    ERIC Educational Resources Information Center

    Haiqi, Zhang; Yamazaki, Shigeaki

    1998-01-01

    Evaluates Japanese journals--128 indexed in the 1994 "Journal Citation Reports"--in bibliometric parameters such as impact factors (IFs), mean IFs from citing and cited journals, and self-citing and self-cited rates. Results: only 15 journals, with a wide variation of self-citing and self-cited rates, have obtained a current impact higher than…

  3. Prevalence of health promotion policies in sports clubs in Victoria, Australia.

    PubMed

    Dobbinson, Suzanne Jane; Hayman, Jane Amanda; Livingston, Patricia Mary

    2006-06-01

    In recent years, some health agencies offered sponsorship to sporting associations to promote healthy environments by encouraging clubs to develop health-related policies. However, the extent to which these sponsorship contracts reach their stated aims is of concern. This study aimed to quantify levels of policy development and practice in sports clubs for each of five key health areas, namely smoke-free facilities, sun protection, healthy catering, responsible serving of alcohol and sports injury prevention. Representatives from 932 Victorian sports clubs were contacted by telephone with 640 clubs (69%) participating in the survey. Results suggested that the establishment of written policies on the key health areas by sports clubs varied widely by affiliated sport and health area: 70% of all clubs with bar facilities had written policies on responsible serving of alcohol, ranging from 58% of tennis clubs to 100% of diving and surfing clubs. In contrast, approximately one-third of sports clubs had a smoke-free policy, with 36% of tennis, 28% of country football and 28% of men's cricket clubs having policy. Moreover, 34% of clubs overall had established sun protection policy, whereas clubs competing outside during summer months, [diving (86%) and life-saving (81%)] were most likely to have a written sun protection policy. Injury prevention policies were established in 30% of sports clubs, and were most common among football (56%), diving (43%) and life-saving (41%). This study suggests that policy development for health promotion can be achieved in sports clubs when it is well supported by health agencies and consideration is given to the appropriateness of the specific behaviours to be encouraged for a given sport. Communication between associations and clubs needs to be monitored by health agencies to ensure support and resources for policy development to reach the club level. PMID:16403799

  4. Results of Second Outdoor Comparison Between Absolute Cavity Pyrgeometer (ACP) and Infrared Integrating Sphere (IRIS) Radiometer at PMOD (Presentation)

    SciTech Connect

    Reda, I.; Grobner, J.; Wacker, S.

    2014-01-01

    The Absolute Cavity Pyrgeometer (ACP) and InfraRed Integrating Sphere radiometer (IRIS) are developed to establish a world reference for calibrating pyrgeometers with traceability to SI units. The two radiometers are un-windowed with negligible spectral dependence, and traceable to SI units through the temperature scale (ITS-90). The second outdoor comparison between the two designs was held from September 30 to October 11, 2013 at the Physikalisch-Metorologisches Observatorium Davos (PMOD). The difference between the irradiance measured by ACP and that of the IRIS was within 1 W/m2 (3 IRISs: PMOD + Australia + Germany). From the first and second comparisons, a difference of 4-6 W/m2 was observed between the irradiance measured by ACP&IRIS and that of the interim World Infrared Standard Group (WISG). This presentation includes results from the first and second comparison in an effort to establish the world reference for pyrgeometer calibrations, a key deliverable for the World Meteorological Organization (WMO), and the DOE-ASR.

  5. Performance of Malaysian Medical Journals.

    PubMed

    Abrizah, Abdullah

    2016-03-01

    Indexation status matters for scholarly journal prestige and trust. The performance of Malaysian medical journals at the international level is gauged through the global citation databases, and at the national level through MyCite, a national citation indexing system. The performance indicators include journals publication productivity, the citations they garner, and their scores on other bibliometric indices such as journal impact factor (IF), and h-index. There is a growing consciousness amongst journal editorials to improve quality and increase chances of getting indexed in MyCite. Although it is now possible to gauge journal performance within Malaysia, through MyCite, the government and public are concerned about journal performance in international databases. Knowing the performance of journals in MyCite will help the editors and publishers to improve the quality and visibility of Malaysian journals and strategise to bring their journal to the international level of indexation. PMID:27547108

  6. Performance of Malaysian Medical Journals

    PubMed Central

    Abrizah, Abdullah

    2016-01-01

    Indexation status matters for scholarly journal prestige and trust. The performance of Malaysian medical journals at the international level is gauged through the global citation databases, and at the national level through MyCite, a national citation indexing system. The performance indicators include journals publication productivity, the citations they garner, and their scores on other bibliometric indices such as journal impact factor (IF), and h-index. There is a growing consciousness amongst journal editorials to improve quality and increase chances of getting indexed in MyCite. Although it is now possible to gauge journal performance within Malaysia, through MyCite, the government and public are concerned about journal performance in international databases. Knowing the performance of journals in MyCite will help the editors and publishers to improve the quality and visibility of Malaysian journals and strategise to bring their journal to the international level of indexation. PMID:27547108

  7. The Supernova Club: Urban Youth Engagement that Works

    NASA Astrophysics Data System (ADS)

    Sakimoto, Philip J.; Luckey, V.; Balsara, D.

    2008-05-01

    One of IYA's goals is to promote greater involvement by underrepresented minorities in scientific and engineering careers. IYA can serve as a catalyst for such involvement, but ultimate success requires a longer-term approach. The Supernova Club is an experiment in such a long-term approach. The goal is to see if engagement in a year-round astronomy club can propel youths from some of the most severely disadvantaged areas of our region into careers in science. We recruited club members by bringing astronomy activities to over a hundred youths ages 10-16 who were on campus in Summer 2007 for Notre Dames’ National Youth Sports Program (NYSP). Approximately 20 percent of the participants, most of who were underrepresented minorities and from below poverty level, expressed interest in joining an after-school astronomy club, and thirteen of them ultimately did so. The club meets one evening a week at Notre Dame's Robinson Community Learning Center. Center staff provide extensive support with logistics, meals, training in social skills and conduct, and communications with parents. Notre Dame scientists, assisted by local teachers, provide weekly activities. After one year, the club members have shown large improvements in interest in science and astronomy, ability to focus on tasks or discussions, and general behavior at school and at home. Funding for this first pilot year was provided through education supplements to HST research grants. With NASA space science education funding currently on an indefinite stand down, we are seeking other funds with which to carry on this experiment.

  8. Making Every Day Count: Boys & Girls Clubs' Role in Promoting Positive Outcomes for Teens

    ERIC Educational Resources Information Center

    Arbreton, Amy

    2009-01-01

    The third in a series of reports from P/PV's three-year study of the role Boys & Girls Clubs play in the lives of the youth they serve, "Making Every Day Count" examines how Club participation is related to youth's positive and healthy development in three outcome areas identified by Boys & Girls Clubs of America as central to its mission: good…

  9. 7 CFR 795.10 - Club, society, fraternal or religious organization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Club, society, fraternal or religious organization... General § 795.10 Club, society, fraternal or religious organization. Each individual club, society..., society, fraternal or religious organization is engaged in the production of crops as a separate...

  10. Raising Money Through Gift Clubs: A Survey of Techniques at 42 Institutions.

    ERIC Educational Resources Information Center

    Sweeney, Robert D., Comp.

    The way that 42 private schools, colleges, and universities use gift clubs to motivate donors is examined. Based on a nationwide survey, information is presented on the clubs' origins, requirements for membership, methods of enlisting new members, and ways of encouraging current members to increase gifts. Attention is also directed to the clubs'…

  11. Toward an Ecstasy and Other Club Drug (EOCD) Prevention Intervention for Rave Attendees

    ERIC Educational Resources Information Center

    Yacoubian, George S., Jr.; Miller, Sarah; Pianim, Selwyn; Kunz, Michael; Orrick, Erin; Link, Tanja; Palacios, Wilson R.; Peters, Ronald J.

    2004-01-01

    A growing body of recent research has identified that "rave" attendees are at high risk for the use of "club drugs," such as 3,4-methylenedioxymeth-amphetamine (MDMA or "ecstasy"). Rave attendees, however, comprise only one of several club-going populations. In the current study, we explore the prevalence of ecstasy and other club drug (EOCD) use…

  12. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7)-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption provided by... general, this exemption extends to social and recreation clubs which are supported solely by...

  13. 26 CFR 1.501(c)(7)-1 - Social clubs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Social clubs. 1.501(c)(7)-1 Section 1.501(c)(7)-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(c)(7)-1 Social clubs. (a) The exemption provided by... general, this exemption extends to social and recreation clubs which are supported solely by...

  14. Almost All Start but Who Continue? A Longitudinal Study of Youth Participation in Swedish Club Sports

    ERIC Educational Resources Information Center

    Jakobsson, Britta Thedin; Lundvall, Suzanne; Redelius, Karin; Engstrom, Lars-Magnus

    2012-01-01

    Many young people in Sweden stop participating in club sports during their teens, but some continue. Drawing on a longitudinal study, the aim of this article is to highlight some of the characteristics of teenagers who continue with club sports and to discuss the relation between club-sport participation and social and cultural conditions, with…

  15. Charismatic Cops, Patriarchs and a Few Good Women: Leadership, Club Culture and Young Peoples' Drinking

    ERIC Educational Resources Information Center

    Kelly, Peter; Hickey, Chris; Cormack, Sue; Harrison, Lyn; Lindsay, Jo

    2011-01-01

    The paper reports on key findings of a research project that examined the roles that community-based sporting clubs in the Australian state of Victoria play in shaping young people's understandings and uses of alcohol. Our research imagined clubs as community hubs that are located in complex networks that impact on the ways that clubs understand…

  16. Coaches' Perceptions of French Sports Clubs: Health-Promotion Activities, Aims and Coach Motivation

    ERIC Educational Resources Information Center

    Van Hoye, Aurélie; Sarrazin, Philippe; Heuzé, Jean-Philippe; Kokko, Sami

    2015-01-01

    Background: Given the benefits of participating in sport, sports clubs have been recognised as health promoting organizations. To examine health-promotion activities in Finnish sports clubs, Kokko et al. developed a set of standards for health-promoting sports clubs (HPSC). Objective: The present study extends this line of research, by (1)…

  17. Sources of Information Used by Teachers in Professional Development Book Club Discussions

    ERIC Educational Resources Information Center

    Galloway, Nicole H.

    2010-01-01

    The research questions were: What sources of information do teachers use in their book-club discussions; and is there variability among teachers in which sources of information they use in book club discussions? Sources of information were described in four categories: (a) the Book-Club Text that is read and discussed by the book club…

  18. An Academic Club Service Learning Project as a Demonstration of Experiential Teaching Tools

    ERIC Educational Resources Information Center

    Bonczek, James L.; Snyder, Lori Unruh; Ellis, Larry R.

    2007-01-01

    We describe our pedagogical approaches and experiences with an academic club service learning project (one semester, 20 club participants, including both graduate students and lower and upper-level undergraduates). Our service learning project responds to the recent demand for more community service-based club projects within the College of…

  19. Prescription Drug Misuse Among Club Drug-Using Young Adults

    PubMed Central

    Kelly, Brian C.; Parsons, Jeffrey T.

    2009-01-01

    Nonmedical prescription (Rx) drug use has recently increased, particularly among young adults. Using time-space sampling to generate a probability-based sample of club-going young adults (18–29), 400 subjects provided data on Rx drug misuse. Club-going young adults misuse Rx drugs at high rates. An overwhelming majority of the sample indicated lifetime use of pain killers, sedatives, and stimulants. A majority indicated recent pain killer use. Variations by gender and sexuality exist in this population. Young lesbian/bisexual women emerged as the group most likely to abuse Rx drugs. Research into the contexts influencing these patterns is imperative. PMID:17994483

  20. Method of transportation and drinking among club patrons

    PubMed Central

    Bourdeau, Beth; Miller, Brenda A.; Johnson, Mark B.; Voas, Robert B.

    2015-01-01

    Objective The current study examines the variation in alcohol use among nightclub patrons under three transportation conditions: those who departed from a club using modes of transportation other than cars or motorcycles (e.g., pedestrians, bicyclists, subway riders); those who were passengers of drivers (auto/taxi passenger patrons); and those who drove from the club (driving patrons). We seek to determine whether patrons' choice for how to leave the club contributes to their risk, as assessed by blood alcohol concentrations (BAC), after controlling for other factors that may contribute to their BAC including demographic characteristics and social drinking group influences. Methods Data were collected from social drinking groups as they entered and exited clubs for 71 different evenings at ten clubs from 2010 through 2012. Using portal methodology, a research site was established proximal to club entrances. Each individual participant provided data on themselves and others in their group. The present analyses are based upon 1833 individuals who completed both entrance and exit data. Our outcome variable is blood alcohol content (BAC) based upon breath tests attained from patrons at entrance and exit from the club. Independent variables include method of transportation, social group characteristics, drug use, and personal characteristics. We use step-wise multiple regressions to predict entrance BAC, change in BAC from entrance to exit, and exit BAC: first entering individual demographic characteristics, then entering group characteristics, then drug use, and finally entering method of transportation (two dummy coded variables such that drivers are the referent category). Results In sum, in all three of our analyses, only three variables are consistently predictive of BAC: presence of a group member who is frequently drunk and non-driving modes of transportation, either being the passenger or taking alternate methods of transportation. In particular, taking an

  1. Book clubs--outreach opportunities for hospital libraries.

    PubMed

    Stephenson, Priscilla L; Clever, Shannon; Coady, Teresa R; Ender, Deniz; Heyd, Michael; Peth, Sara

    2014-01-01

    Book clubs and discussion groups provide opportunities for hospital librarians to reach out to staff from all areas of their facilities while introducing them to literature reflecting participants' personal and professional interests. Librarians presenting these case studies have coordinated local book clubs where topics ranged from titles about the nature of healing, to leadership development, and patient-centered care. Some also included contemporary novels of interest to participants. No matter the setting or scope of material discussed, each group has provided unique networking opportunities for staff to meet others working in various departments of their facilities. PMID:25316078

  2. The professionalization of Carl G. Jung's analytical psychology clubs.

    PubMed

    Samuels, A

    1994-04-01

    This paper addresses (1) the history of a cluster of unusual institutions-analytical psychology clubs--which started in 1916 and by 1934 had become established in many of the countries in the world in which there was interest in the analytical psychology of Carl G. Jung; (2) the conflicts involved in trying to unite the relatively informal earlier "Jung Clubs" with the more formal societies being established by the increasing numbers of professionally trained analysts; and (3) the wider cultural and social issues included in the professionalization of analytical psychology. PMID:8034963

  3. Acyl-ACP thioesterases from castor (Ricinus communis L.): an enzymatic system appropriate for high rates of oil synthesis and accumulation.

    PubMed

    Sánchez-García, Alicia; Moreno-Pérez, Antonio J; Muro-Pastor, Alicia M; Salas, Joaquín J; Garcés, Rafael; Martínez-Force, Enrique

    2010-06-01

    Acyl-acyl carrier protein (ACP) thioesterases are enzymes that terminate the intraplastidial fatty acid synthesis in plants by hydrolyzing the acyl-ACP intermediates and releasing free fatty acids to be incorporated into glycerolipids. These enzymes are classified in two families, FatA and FatB, which differ in amino acid sequence and substrate specificity. In the present work, both FatA and FatB thioesterases were cloned, sequenced and characterized from castor (Ricinus communis) seeds, a crop of high interest in oleochemistry. Single copies of FatA and FatB were found in castor resulting to be closely related with those of Jatropha curcas. The corresponding mature proteins were heterologously expressed in Escherichia coli for biochemical characterization after purification, resulting in high catalytic efficiency of RcFatA on oleoyl-ACP and palmitoleoyl-ACP and high efficiencies of RcFatB for oleoyl-ACP and palmitoyl-ACP. The expression profile of these genes displayed the highest levels in expanding tissues that typically are very active in lipid biosynthesis such as developing seed endosperm and young expanding leaves. The contribution of these two enzymes to the synthesis of castor oil is discussed. PMID:20382402

  4. The Club of Rome and its computer.

    PubMed

    Chase, S

    1973-03-01

    When the Club of Rome, an assemblage of 75 scientists and businessmen gathered to study the ''predicament of mankind in the face of technology growing at an exponential rate,'' issued its computer study it launched a battle between proponents of gross national product and those favoring quality of life. The computer simulation studied the interaction of population growth, food supply, inductrial production, resource use, and pollution under varying conditions. It concluded that our industrial system is headed for too many people in relation to food and living space, too much production in relation to natural resources, and for too much pollution. This will affect all countries. The traditional economists say the continued growth of the gross national product is the only way to ensure better living conditions while the ecologists point out that quality of life is being destroyed. The author cites arguments both for and against the quality-of-life view. The problem is that continued industrial growth creates wants as well as satisfying them and leads to waste as well as needful consumption. John Stuart Mill stated 100 years ago that the world could not support continued technological expansion and society must reach an equilibrium. 8 steps must be taken if the planet is to reach such an equilibrium, which is essential to the survival of all: 1) a zero rate of population growth, although there may be variations between countries with some over and some under; 2) a zero rate of industrial output with overall new investment equal to overall rate of industrial depreciation; 3) a policy of recycling and conserving material resources; 4) an adequate budget of food, shelter, clothing, health services, and education for every human being (a budget which does not allow for autos and air conditioning); 5) a sharp decline in consumption of material goods in affluent societies with a corresponding shift to more services and an increase in material goods for low energy societies

  5. Women's involvement in community development: the story of Korea's Family Planning Mothers' Club.

    PubMed

    Bong Soo Kang

    1990-04-01

    Women's participation in Korea's economic and community development programs has increased since the early 1960s. The Family Planning (FP) Mothers' Club was organized by Planned Parenthood Federation of Korea (PPFK) in rural villages. Early in 1968, PPFK recruited 139 county field officers. They were put into county health centers, one in each county. They helped set up the Mothers' Clubs. Women wanted to have these clubs, but husbands and village elders did not want them to get together and talk about family planning. 12,650 Mothers' Clubs were established in the 1st year; about 2000 clubs were organized annually after that. In 1976, there were 27,292 village-level Mothers' Clubs with 750,000 members. Some 2000 clubs have been disbanded. The purposes of the clubs are to promote practice, to make FP part of everyday life, to foster a cooperative spirit among members, and to push active participation in community development so that productivity is increased and optimal surroundings created. The Mothers' Clubs were classified into: 1) the village and grass roots clubs; 2) their chairpersons, who constituted the Eup and Myon clubs; and 3) the county federation of Mothers' Clubs. Membership is open to all married village women, aged 20 to 45. Each village club has 1 elected chairperson, 1 vice chairperson, and 1 secretary. There was an average of 23 members per club in 1968, but this grew to 30 in 1972. Club programs include social activities, community development, cooperative work, income- generation projects, a Mothers' Bank, and FP. PPFK supports the clubs by financial aid, material aid, technical aid, training, and awards and acknowledgements. Mothers' clubs have promoted FP and served as distribution points for contraceptives. Environments were drastically changed in many villages through the community development work of the Mothers' Clubs. The traditional role of Korean women was early marriage and the production of at least 1 son. The Mothers' Clubs

  6. 75 FR 34374 - Safety Zone; Stockton Ports Baseball Club/City of Stockton, 4th of July Fireworks Display...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Stockton Ports Baseball Club/City of... Ports Baseball Club and the City of Stockton will sponsor the Stockton Ports Baseball Club/City of... Ports Baseball Club/City of Stockton 4th of July Fireworks Display, Stockton, CA. (a) Location....

  7. A Cross-Cultural Study on Meaning and the Nature of Children's Experiences in Australian and French Swimming Clubs

    ERIC Educational Resources Information Center

    Light, Richard

    2010-01-01

    This article reports on a study conducted in Australia and France that inquired into the meaning and the nature of children's experiences of being in swimming clubs with a focus on the positive aspects of membership that keep them in their clubs. Three-month long case studies were conducted in a club in Australia and in a club in France, employing…

  8. Sexy ladies sexing ladies: women as consumers in strip clubs.

    PubMed

    Wosick-Correa, Kassia R; Joseph, Lauren J

    2008-01-01

    Recent shifts in the consumer base of the sex industry have involved greater female attendance in strip clubs. This article examines how strip clubs and dancers incorporate female patrons into a sexualized space traditionally designed for men by identifying three interactional processes: passing over, sidestaging, and tailoring. We suggest dancers pass over women because they perceive female patron behavior to include resistance to "buying the game" and spending patterns that diverge from male customers. Drawing on Goffman's dramaturgical analysis, we suggest the dynamic relationship between dancer and female patron involves what we term sidestaging, which refers to both dancers' disclosure and how the club's spatial organization inhibits the construction of women as customers through sharing gendered spaces, such as the bathroom. We argue that when a dancer tailors her lap dance for a female patron, she succeeds in acknowledging the female customer's sexual subjectivity and potential same-sex desires by providing an individualized avenue for exploring an erotic experience. Finally, we discuss data implications for understanding how same-sex desire and sexual identity operate in an environment that eroticizes the female form, and how the strip club becomes a potential space for engaging in same-sex eroticism that includes elements of play. PMID:18686149

  9. The Morehouse College Glee Club: History and Recent Highlights.

    ERIC Educational Resources Information Center

    Morrow, David

    1987-01-01

    The history of the Morehouse College Glee Club, founded around 1911 at the Black college, is highlighted by appearances before such notables as Franklin D. Roosevelt, Martin Luther King, Jr., Haile Selassie, Jimmy Carter, and Benjamin E. Mays and performances with people such as Robert Shaw, Leontyne Price, Diahann Carroll, Maynard Jackson, Billy…

  10. Bears, Trolls, and Pagemasters: Learning about Learners in Book Clubs.

    ERIC Educational Resources Information Center

    Frank, Carolyn R.; Dixon, Carol N.; Brandts, Lois R.

    2001-01-01

    Illustrates how in one particular second-grade classroom students had opportunities for learning the academic and social content of literature while simultaneously engaging in the processes and practices of reading. Focuses on the kinds of opportunities offered to students in their involvement in Book Clubs and how those opportunities occur when…

  11. Trailblazers, Stargazers. Program Guide for the Texas Reading Club, 1988.

    ERIC Educational Resources Information Center

    Noe, Marie

    This guide outlines the suggested program for 1988 for the Texas Reading Club, an activity sponsored cooperatively by local libraries and the Texas State Library to encourage children and their parents to read and use the library. The general theme, "Trailblazers, Stargazers," focuses on people who do new things, go new places, experiment,…

  12. Marshall Amateur Radio Club experiment (MARCE) post flight data analysis

    NASA Technical Reports Server (NTRS)

    Rupp, Charles C.

    1987-01-01

    The Marshall Amateur Radio Club Experiment (MARCE) data system, the data recorded during the flight of STS-61C, the manner in which the data was reduced to engineering units, and the performance of the student experiments determined from the data are briefly described.

  13. Rich-club organization of the newborn human brain

    PubMed Central

    Ball, Gareth; Aljabar, Paul; Zebari, Sally; Tusor, Nora; Arichi, Tomoki; Merchant, Nazakat; Robinson, Emma C.; Ogundipe, Enitan; Rueckert, Daniel; Edwards, A. David; Counsell, Serena J.

    2014-01-01

    Combining diffusion magnetic resonance imaging and network analysis in the adult human brain has identified a set of highly connected cortical hubs that form a “rich club”—a high-cost, high-capacity backbone thought to enable efficient network communication. Rich-club architecture appears to be a persistent feature of the mature mammalian brain, but it is not known when this structure emerges during human development. In this longitudinal study we chart the emergence of structural organization in mid to late gestation. We demonstrate that a rich club of interconnected cortical hubs is already present by 30 wk gestation. Subsequently, until the time of normal birth, the principal development is a proliferation of connections between core hubs and the rest of the brain. We also consider the impact of environmental factors on early network development, and compare term-born neonates to preterm infants at term-equivalent age. Though rich-club organization remains intact following premature birth, we reveal significant disruptions in both in cortical–subcortical connectivity and short-distance corticocortical connections. Rich club organization is present well before the normal time of birth and may provide the fundamental structural architecture for the subsequent emergence of complex neurological functions. Premature exposure to the extrauterine environment is associated with altered network architecture and reduced network capacity, which may in part account for the high prevalence of cognitive problems in preterm infants. PMID:24799693

  14. Argonne Director Eric Isaacs addresses the National Press Club

    ScienceCinema

    Eric Isaccs

    2010-01-08

    Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

  15. Invent the Future--READ! 2000 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Bass, Martha; Davis, Robin Works; Harris, Marlive; Marcum, Paul

    The Texas Reading Club is designed to encourage youth to read for pleasure and to promote library usage.A statewide theme is selected each year that emphasizes ways in which reading expands young minds and encourages children to use their imaginations. The year 2000's theme, "Invent the future! READ!," emphasizes ways in which reading expands…

  16. Imaginary Indians: Representations of Native Americans in Scholastic Reading Club

    ERIC Educational Resources Information Center

    Chaudhri, Amina; Schau, Nicole

    2016-01-01

    Scholastic Reading Clubs are a popular and inexpensive way for teachers to build classroom libraries and for parents to purchase books for their children. The books made accessible to children through the order forms are assumed to be suitable for young readers in terms of their content, popularity, currency, and curricular relevance.…

  17. The Environmental Message of Audubon and the Sierra Club Bulletin

    ERIC Educational Resources Information Center

    Hoesterey, John; Bowman, James S.

    1976-01-01

    This study attempted to determine the impact of environmental values on two periodicals: Audubon and the Sierra Club Bulletin. The two periodicals were analyzed for the period 1969-1974. Many conclusions are presented including that the Audubon Society may be undergoing an organizational change by becoming more politically oriented. (BT)

  18. Using Digital Classrooms to Conduct 4-H Club Meetings

    ERIC Educational Resources Information Center

    West, Patricia; Fuhrman, Nicholas E.; Morgan, A. Christian; Duncan, Dennis W.

    2012-01-01

    Using computer technology and digital classrooms to conduct 4-H Club meetings is an efficient way to continue delivering quality 4-H programming during times of limited resources and staff. Nineteen Junior and Senior 4-H'ers participated in seven digital classroom workshops using the Wimba Classroom application. These digital classroom…

  19. "Tipping" Teachers toward Change: Developing Leadership Characteristics through Book Club

    ERIC Educational Resources Information Center

    Klinker, JoAnn Franklin; Watson, Patricia A.; Furgerson, Paige; Halsey, Pamela; Janisch, Carole

    2010-01-01

    Teacher leadership is difficult because teachers often lack encouragement and opportunities to implement ideas that deliberately and strategically interact with and tap power structures in schools. In this study, a book club of university faculty and middle school teachers provided teacher leaders with a template for change around concepts…

  20. Extracurricular School Clubs: A Time for Fun and Learning

    ERIC Educational Resources Information Center

    Pence, Alicia R.; Dymond, Stacy K.

    2015-01-01

    Inclusion in school clubs affords students with severe disabilities learning opportunities as well as a natural context for addressing curricula. These learning opportunities expand the number of settings in which students can practice, master, and generalize skills associated with priority IEP objectives. Teaching skills within natural activities…

  1. Mission Possible: Spy a Book! 2003 Texas Reading Club Manual.

    ERIC Educational Resources Information Center

    Heard, Adriana Flores; Ingham, Donna; McDermott, Joe; Meyer, Sally; Parrish, Leila; Schill, Victor; Trevino, Rose

    The purpose of this manual for the 2003 Texas Reading Club, "Mission Possible: Spy a Book!" is to assist library staff who serve youth by suggesting ideas for programs that will attract children to the library. The following chapters are included: (1) Marketing, Cooperation and PR; (2) Serving Children with Disabilities; (3) Theme Songs; (4)…

  2. The Secret Club Project: Exploring Miscarriage through the Visual Arts.

    ERIC Educational Resources Information Center

    Seftel, Laura

    2001-01-01

    Examines art as a means to understand the physical and emotional loss of miscarriage. "The Secret Club Project," an innovative exhibit featuring 10 women artists' visual responses to miscarriage, is described. Rituals related to pregnancy loss are reviewed, as well as artists' and art therapists' use of the creative process to move through grief.…

  3. 8. INTERIOR VIEW OF CLUB HOUSE BEDROOM ON SOUTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR VIEW OF CLUB HOUSE BEDROOM ON SOUTHEAST CORNER OF HOTEL. BOAT HOUSE AND DOCK VISIBLE FROM WINDOW ON LEFT; SWAN FALLS POWER HOUSE AND CONSTRUCTION SITE VISIBLE FROM WINDOW ON RIGHT. CAMERA FACING WEST/NORTHWEST. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  4. "Space Capers." Texas Reading Club 1982: A Librarian's Planning Handbook.

    ERIC Educational Resources Information Center

    Rudd, Peggy Jemelka

    Originally designed as a summer program to be offered through the network of bookmobiles and rural public libraries in the state, the Texas Reading Club is now also promoted year round by school and institutional libraries to encourage young readers and to acquaint them with libraries and their services. A theme, formats and ideas, and basic…

  5. Boys and Girls Clubs in Public Housing. Final Research Report.

    ERIC Educational Resources Information Center

    Pope, Carl E.; And Others

    This report presents findings and recommendations resulting from the evaluation of programs implemented in 15 cities by the Boys and Girls Clubs of America. These programs were implemented to distribute variations on the "Weed and Seed" program and its provision of crime and drug prevention programs. The overall goal of Weed and Seed was to form…

  6. A Case Study of a Mother/Daughter Science Club.

    ERIC Educational Resources Information Center

    Chandler, Frances Tate; Parsons, Sharon

    This paper describes a case study of a Mother/Daughter Science Club which was established to explore the issue of adolescent girls' increasingly negative attitudes towards science and math. Data was collected on participants' (n=40, 20 pre-adolescent fifth-grade girls and their mothers) attitudes toward math and science through the use of…

  7. Tracking Club Sport Participation from Childhood to Early Adulthood

    ERIC Educational Resources Information Center

    Richards, Rosalina; Williams, Sheila; Poulton, Richie; Reeder, Anthony I.

    2007-01-01

    This study examined the strength of tracking sport participation from childhood to early adulthood among the Dunedin Multidisciplinary Health and Development Study cohort. Participation in sport, dance, or gymnastics as part of a club or group (outside of school) was assessed at ages 7, 9, 15, 18, and 21 years. In addition to the traditionally…

  8. Transnational Alliances: "La Clase Mágica--Nepohualtzitzin" Ethnomathematics Club

    ERIC Educational Resources Information Center

    Prieto, Linda; Claeys, Lorena; González, Everardo Lara

    2015-01-01

    This article exposes the ancient "Nepohualtzitzin" as an important contemporary mathematical tool. The design and development of "Nepohualtzitzin" Ethnomathematics Clubs (NECs) in predominantly Latina/o and low-income schools is also presented. NECs provide informal learning opportunities to develop and strengthen cultural…

  9. Kids Food CyberClub. Teacher's Guide. First Edition.

    ERIC Educational Resources Information Center

    Belyea, Monica

    This guide is designed to help teachers educate students to be healthier now and in the future. It presents fun, learner-centered activities about nutrition, food, hunger, and food sources. It offers an overview of each section of the Kids Food CyberClub web site, and classroom activities teachers can use to expand on information students will…

  10. Teens, Crime, and the Community in Boys & Girls Clubs.

    ERIC Educational Resources Information Center

    Carlson, Andrea

    Teens, Crime, and the Community (TCC) curriculum creates an awareness among teens of the crime problems facing our communities and how they affect our nation. It encourages youth to take responsibility for reducing crime and victimization, making schools and neighborhoods safer. Boys and Girls Clubs offer a variety of programs for youth, and TCC…

  11. Bullying 101: The Club Crew's Guide to Bullying Prevention

    ERIC Educational Resources Information Center

    PACER Center, 2013

    2013-01-01

    "Bullying 101" is the Club Crew's Guide to Bullying Prevention. A visually-friendly, age-appropriate, 16-page colorful guide for students to read or for parents to use when talking with children, this guide describes and explains what bullying is and is not, the roles of other students, and tips on what each student can do to prevent…

  12. 17. Interior of upper level (Turf Club level) of south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Interior of upper level (Turf Club level) of south and west additions to the Clubhouse. Camera pointed W. Stairs in foreground lead to the 'Gallery' room. Stairs in background lead to the 'Callahan' room. 'Broderick' room (not shown) is entered from south side of 'Gallery' room. (July 1993) - Longacres, Clubhouse & Additions, 1621 Southwest Sixteenth Street, Renton, King County, WA

  13. 27 CFR 31.41 - Clubs or similar organizations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Clubs or similar organizations. 31.41 Section 31.41 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS ALCOHOL BEVERAGE DEALERS Activities Subject to This Part Certain Organizations, Agencies, and Persons...

  14. Argonne Director Eric Isaacs addresses the National Press Club

    SciTech Connect

    Eric Isaccs

    2009-09-17

    Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

  15. YALA Journal, 1989.

    ERIC Educational Resources Information Center

    YALA Journal, 1989

    1989-01-01

    This annual publication of the Young Adult Learning Academy (YALA) presents the art and writing of students in YALA. (YALA provides educational services to young people who have dropped out of school, are between 16 and 24 years of age, and read below the eighth-grade level.) This journal reflects the authors' and artists' perceptions of what it…

  16. Decoupling the scholarly journal.

    PubMed

    Priem, Jason; Hemminger, Bradley M

    2012-01-01

    Although many observers have advocated the reform of the scholarly publishing system, improvements to functions like peer review have been adopted sluggishly. We argue that this is due to the tight coupling of the journal system: the system's essential functions of archiving, registration, dissemination, and certification are bundled together and siloed into tens of thousands of individual journals. This tight coupling makes it difficult to change any one aspect of the system, choking out innovation. We suggest that the solution is the "decoupled journal (DcJ)." In this system, the functions are unbundled and performed as services, able to compete for patronage and evolve in response to the market. For instance, a scholar might deposit an article in her institutional repository, have it copyedited and typeset by one company, indexed for search by several others, self-marketed over her own social networks, and peer reviewed by one or more stamping agencies that connect her paper to external reviewers. The DcJ brings publishing out of its current seventeenth-century paradigm, and creates a Web-like environment of loosely joined pieces-a marketplace of tools that, like the Web, evolves quickly in response to new technologies and users' needs. Importantly, this system is able to evolve from the current one, requiring only the continued development of bolt-on services external to the journal, particularly for peer review. PMID:22493574

  17. Collaborative Teaching in Journalism.

    ERIC Educational Resources Information Center

    Haber, Marian Wynne

    Recently, the Communication Department at the University of Texas at Arlington offered an innovative news editing course taught collaboratively by a journalism professor and an editor of the "Fort Worth Star-Telegram," a metropolitan daily newspaper. In 1990 the course was continued on the model describes by R. L. Gates (1989), and in this class…

  18. Parent's Journal. [Videotape Series].

    ERIC Educational Resources Information Center

    1999

    Parent's Journal is a set of 16 videotapes for parents of prenatal, infant, and toddler-age children, created by the Alaska Native Home Base Video Project of the Tlingit and Haida Head Start Program. This series offers culturally relevant solutions to the challenges of parenting, drawing on the life stories and experiences of capable mothers and…

  19. From Conference to Journal

    ERIC Educational Resources Information Center

    McCartney, Robert; Tenenberg, Josh

    2008-01-01

    Revising and extending conference articles for journal publication benefits both authors and readers. The new articles are more complete, and benefit from peer review, feedback from conference presentation, and greater editorial consistency. For those articles that are appropriate, we encourage authors to do this, and present two examples of such…

  20. JALT Journal, 2001.

    ERIC Educational Resources Information Center

    Fotos, Sandra, Ed.; Jungheim, Nicholas O., Ed.

    2001-01-01

    The two issues in this volume of the "JALT Journal" contain the following articles: "Comprehension and Production Practice in Grammar Instruction: Does Their Combined Use Facilitate Second Language Acquisition?" (Takeo Tanaka); "Professional Development and the JET Program: Insights and Solutions Based on the Sendai City Program" (Anthony Crooks);…

  1. Social Studies Journal, 2003.

    ERIC Educational Resources Information Center

    West, Leo R., Ed.

    2003-01-01

    This theme issue of the "Social Studies Journal" focuses on the worldwide conflict known in the United States as the French and Indian War (1754-1763). The volume is dedicated to examining the conflict in Pennsylvania. Western Pennsylvania became a battle-scarred landscape as the British and French, with their Native American allies, struggled for…

  2. The CATESOL Journal, 2001.

    ERIC Educational Resources Information Center

    Brinton, Donna, Ed.; Ching, Roberta, Ed.

    2001-01-01

    This journal contains the following articles: "Teachers' Perceptions of the Supports and Resources Needed to Prepare English Language Learners for the Future" (Douglas Fisher); "Exploring the Learning Styles of Russian-Speaking Students of English as a Second Language" (Ann C. Wintergerst and Andrea DeCapua); "New Voices in the Classroom:…

  3. Liberal Education and Journalism.

    ERIC Educational Resources Information Center

    Dressel, Paul L.

    A study of liberal education in undergraduate professional schools is presented. Eight types of professional schools were included: agriculture, business administration, education, engineering, journalism, music, nursing, and pharmacy. The study has been conducted along several lines. The first project consisted of the preparation of an extensive…

  4. Framing Journalism Education

    ERIC Educational Resources Information Center

    Abusharif, Ibrahim N.

    2014-01-01

    Examining the growth, incentives, and progress of overseas campuses of major American educational institutions is an important academic pursuit. To have a complete picture, one must also consider the impact these branch campuses are having on the lives of their students. The Northwestern University in Qatar's journalism program was invited to…

  5. Charting Journalism Degrees.

    ERIC Educational Resources Information Center

    Borden, Victor M. H.

    1998-01-01

    Data are presented on the numbers of African Americans, Hispanic Americans, Asian Americans, and total minority group members receiving associate, bachelor's, master's and doctoral degrees in journalism and mass communication in 1997-98. Colleges and universities graduating the most minorities are also ranked. (MSE)

  6. CACD Journal, 2000.

    ERIC Educational Resources Information Center

    Wickwire, Pat Nellor, Ed.

    2000-01-01

    This journal of the California Association for Counseling and Development attempts to identify the current issues of concern in the counseling field and share research to help improve the professional learning community. The articles in this issue include: "The Editor's Message" (Pat Nellor Wickwire); "The CACD President's Message" (Joseph Dear);…

  7. JALT Journal, 1998.

    ERIC Educational Resources Information Center

    JALT Journal, 1998

    1998-01-01

    This journal (published twice a year) is a publication of the Japan Association for Language Teaching (JALT), a nonprofit professional organization of language teachers dedicated to the improvement of language learning and teaching in Japan. JALT's publications and events serve as vehicles for the exchange of new ideas and techniques, and a means…

  8. JALT Journal, 1999.

    ERIC Educational Resources Information Center

    Fotos, Sandra, Ed.

    1999-01-01

    This journal (usually published twice a year) is a publication of the Japan Association for Language Teaching (JALT), a nonprofit professional organization of language teachers dedicated to the improvement of language learning and teaching in Japan. JALT's publications and events serve as vehicles for the exchange of new ideas and techniques, and…

  9. Launching Family Message Journals.

    ERIC Educational Resources Information Center

    Wollman-Bonilla, Julie

    This lesson introduces Family Message Journals, a tool for encouraging family involvement and supporting writing to reflect and learn. First and second graders are led into composing through demonstration, guided writing, and finally independent writing of messages that they will bring home for family to read and write a reply. During the three…

  10. Brazilian History through Journalism.

    ERIC Educational Resources Information Center

    Zaher, Celia Ribeiro; Varella, Maria Angelica

    This paper provides an overview of the beginnings of the newspaper in Brazil with information on the more significant titles and their role in the history of journalism and their impact on social change that occurred between the Imperial and Republican periods. Current collections at the National Library and legal deposit are discussed. It…

  11. Decoupling the scholarly journal

    PubMed Central

    Priem, Jason; Hemminger, Bradley M.

    2011-01-01

    Although many observers have advocated the reform of the scholarly publishing system, improvements to functions like peer review have been adopted sluggishly. We argue that this is due to the tight coupling of the journal system: the system's essential functions of archiving, registration, dissemination, and certification are bundled together and siloed into tens of thousands of individual journals. This tight coupling makes it difficult to change any one aspect of the system, choking out innovation. We suggest that the solution is the “decoupled journal (DcJ).” In this system, the functions are unbundled and performed as services, able to compete for patronage and evolve in response to the market. For instance, a scholar might deposit an article in her institutional repository, have it copyedited and typeset by one company, indexed for search by several others, self-marketed over her own social networks, and peer reviewed by one or more stamping agencies that connect her paper to external reviewers. The DcJ brings publishing out of its current seventeenth-century paradigm, and creates a Web-like environment of loosely joined pieces—a marketplace of tools that, like the Web, evolves quickly in response to new technologies and users' needs. Importantly, this system is able to evolve from the current one, requiring only the continued development of bolt-on services external to the journal, particularly for peer review. PMID:22493574

  12. JALT Journal, 2000.

    ERIC Educational Resources Information Center

    Fotos, Sandra, Ed.

    2000-01-01

    This journal (published twice a year) is a publication of the Japan Association for Language Teaching (JALT), a nonprofit professional organization of language teachers dedicated to the improvement of language learning and teaching in Japan. JALT's publications and events serve as vehicles for the exchange of new ideas and techniques, and a means…

  13. Reinvigorating Science Journals

    ERIC Educational Resources Information Center

    Bricker, Patricia

    2007-01-01

    Science-themed books are wonderful tools for emphasizing the importance of observation and journaling. They can also be used to effectively promote literacy skills in science. This article shares a selection of nature books and the ways teachers and students used them to engage in the process of scientific inquiry. (Contains 3 figures and 10…

  14. Existentialism in New Journalism.

    ERIC Educational Resources Information Center

    Dalmia, Shikha

    In 1977, John C. Merrill, a mass communication scholar, found that many scholars believed that the sixties movement of new journalism is in some way related to existentialism. To find this out, a study identified six main themes of the philosophy of existentialism (as espoused by Jean-Paul Sartre) and looked for the presence of these themes in the…

  15. The Journalism of Uncertainty.

    ERIC Educational Resources Information Center

    Patterson, Joye

    1979-01-01

    Science journalism is in a period of change from its prior position of reporting the pronouncements of scientists to one of challenging the conclusions of scientists and using multiple sources to comment on scientific discovery. It is necessary that educational institutions anticipate the need for competent scientific journalists. (RE)

  16. JALT Journal, 2002.

    ERIC Educational Resources Information Center

    Jungheim, Nicholas O., Ed.

    2002-01-01

    These two journal issues include the following articles: "Assistant Foreign Language Teachers in Japanese High Schools: Focus on the Hosting of Japanese Teachers" (Great Gorsuch); "Communicative Language Teaching (Organizational Effectiveness of Upper Secondary School English Language Departments and Their Commitment toward Communicative Language…

  17. What are Journals for?

    PubMed

    Rallison, S P

    2015-03-01

    'The secret is comprised in three words - work, finish, publish.' Michael Faraday There are many reasons doctors want to publish their work. For most at an early stage in their career, this may be to add a line to their curriculum vitae and advance their careers but for academics, publishing is an expectation. Many will believe they have something important to say, and wish to provoke debate and discussion; others wish to share knowledge and experiences, which in medicine can lead to a satisfying change in clinical practice. All serve to register one's idea and educate others. However, for some, the reason is as basic as money. As we celebrate the 350th anniversary of the first academic publication, perhaps we have come full circle when it comes to why people publish? Publishing is a flourishing business. There were approximately 28,100 active scholarly peer-reviewed journals in mid-2012, collectively publishing about 1.8-1.9 million articles per year. The number of articles published each year and the number of journals have both grown steadily for more than two centuries, by about 3% and 3.5% per year respectively. (1) Journals have a responsibility to refine and define information and act as a scientific filter. Many of us will receive daily invitations in our email inbox from eclectic and new journals that are likely to take anything - is the filter now too porous? But this industry is like any other commercial activity and the supply still far outstrips the demand. Perhaps the internet revolution has merely fuelled our hunger to publish more? The launch of this exciting and innovative series about publishing coincides with the 350th celebration of the publication of the first academic journal. In the age of social media, the first question is 'What are journals for?', which Simon Rallison sets out to answer. Simon is Director of Publications at the Physiological Society, and was previously a journal publisher with Earthscan, Springer and Blackwell. Writing is

  18. Experiencing aggression in clubs: social group and individual level predictors.

    PubMed

    Miller, Brenda A; Bourdeau, Beth; Johnson, Mark; Voas, Robert

    2015-05-01

    To examine the social drinking group's influence on the individual's experiences of physical or sexual aggression at clubs, data were collected from 368 groups (N = 986 individuals). Both group and individual level indicators were examined for impact on self-reports of physical and sexual aggression experiences while at the club. Recent aggressive experiences and perpetration, concerns for group safety, one's own plans and assessment of other group members' plans to drink to the point of intoxication, and personal characteristics were examined, using both individual and group indicators. At exit, participants reported experiencing physical aggression (12.3 %) and sexual aggression (12.6 %) at the club. Using generalized linear mixed modeling to account for nested data (club, event, and group), group level indicators predicted both the individual's physical and sexual aggression experiences. Especially for experiences of physical aggression, group effects are notable. Being in a group whose members recently experienced physical aggression increased the risk for the individual. Interestingly, groups that had higher levels of planned intoxication decreased risks of experiencing aggression, while a discrepancy in these intentions among group members increased the risks. Group effects were also noted for experiencing sexual aggression. High levels of prior experiences for sexual aggression in the group increased the risks for the individual during the event. Also, being in a group that is identified as having at least one member who is frequently drunk increases the risk for experiencing sexual aggression. These findings inform prevention strategies for young adults engaged in high-risk behaviors by targeting social drinking groups who frequent clubs. PMID:24838821

  19. Predictors of experiencing aggression in clubs: Beyond alcohol consumption

    PubMed Central

    Miller, Brenda A.; Bourdeau, Beth; Johnson, Mark; Voas, Robert

    2014-01-01

    To examine the social drinking group's influence on the individual's experiences of physical or sexual aggression at clubs, data were collected from 368 groups (N=986 individuals). Both group and individual level indicators were examined for impact on self-reports of physical and sexual aggression experiences while at the club. Recent aggressive experiences and perpetration, concerns for group safety, one's own plans and assessment of other group members' plans to drink to the point of intoxication, and personal characteristics were examined, using both individual and group indicators. At exit, participants reported experiencing physical aggression (12.3%) and sexual aggression (12.6%) at the club. Using generalized linear mixed modeling to account for nested data (club, event, and group), group level indicators predicted both the individual's physical and sexual aggression experiences. Especially for experiences of physical aggression, group effects are notable. Being in a group whose members recently experienced physical aggression, increased the risk for the individual. Interestingly, groups that had higher levels of planned intoxication decreased risks of experiencing aggression, while a discrepancy in these intentions among group members increased the risks. Group effects were also noted for experiencing sexual aggression. High levels of prior experiences for sexual aggression in the group increased the risks for the individual during the event. Also, being in a group that is identified as having at least one member who is frequently drunk, increases the risk for experiencing sexual aggression. These findings inform prevention strategies for young adults engaged in high risk behaviors by targeting social drinking groups who frequent clubs. PMID:24838821

  20. Three journal similarity metrics and their application to biomedical journals.

    PubMed

    D'Souza, Jennifer L; Smalheiser, Neil R

    2014-01-01

    In the present paper, we have created several novel journal similarity metrics. The MeSH odds ratio measures the topical similarity of any pair of journals, based on the major MeSH headings assigned to articles in MEDLINE. The second metric employed the 2009 Author-ity author name disambiguation dataset as a gold standard for estimating the author odds ratio. This gives a straightforward, intuitive answer to the question: Given two articles in PubMed that share the same author name (lastname, first initial), how does knowing only the identity of the journals (in which the articles were published) predict the relative likelihood that they are written by the same person vs. different persons? The article pair odds ratio detects the tendency of authors to publish repeatedly in the same journal, as well as in specific pairs of journals. The metrics can be applied not only to estimate the similarity of a pair of journals, but to provide novel profiles of individual journals as well. For example, for each journal, one can define the MeSH cloud as the number of other journals that are topically more similar to it than expected by chance, and the author cloud as the number of other journals that share more authors than expected by chance. These metrics for journal pairs and individual journals have been provided in the form of public datasets that can be readily studied and utilized by others. PMID:25536326

  1. The Writer's Journal: 40 Contemporary Writers and Their Journals.

    ERIC Educational Resources Information Center

    Bender, Sheila, Ed.

    This anthology presents excerpts from the journals of 40 of today's most noted writers, along with their comments on the role of journal-keeping in creating their art. Besides being generally instructional to other writers and a lesson in how to create a personal journal, the anthology is a look at writers in the midst of creating. It includes…

  2. Positioning Open Access Journals in a LIS Journal Ranking

    ERIC Educational Resources Information Center

    Xia, Jingfeng

    2012-01-01

    This research uses the h-index to rank the quality of library and information science journals between 2004 and 2008. Selected open access (OA) journals are included in the ranking to assess current OA development in support of scholarly communication. It is found that OA journals have gained momentum supporting high-quality research and…

  3. Linking Electronic Journals: Lessons from the Open Journal Project.

    ERIC Educational Resources Information Center

    Hitchcock, Steve; Carr, Les; Hall, Wendy; Harris, Steve; Probets, Steve; Evans, David; Brailsford, David

    1998-01-01

    Describes the Open Journal project, funded by the United Kingdom Electronic Libraries (eLib) program. Discusses aspects of publishing being transformed by the World Wide Web; Open Journal demonstrators and linking features and types; user responses; building better open journals; and post-project application plans of publishers. (Author/AEF)

  4. ASM Journals Eliminate Impact Factor Information from Journal Websites.

    PubMed

    Casadevall, Arturo; Bertuzzi, Stefano; Buchmeier, Michael J; Davis, Roger J; Drake, Harold; Fang, Ferric C; Gilbert, Jack; Goldman, Barbara M; Imperiale, Michael J; Matsumura, Philip; McAdam, Alexander J; Pasetti, Marcela F; Sandri-Goldin, Rozanne M; Silhavy, Thomas; Rice, Louis; Young, Jo-Anne H; Shenk, Thomas

    2016-01-01

    Many scientists attempt to publish their work in a journal with the highest possible journal impact factor (IF). Despite widespread condemnation of the use of journal IFs to assess the significance of published work, these numbers continue to be widely misused in publication, hiring, funding, and promotion decisions (1, 2). PMID:27408939

  5. Meet the APS Journal Editors

    NASA Astrophysics Data System (ADS)

    2016-05-01

    The Editors of the APS journals invite you to join them for conversation. The Editors will be available to answer questions, hear your ideas, and discuss any comments about the journals. All are welcome. Light refreshments will be served.

  6. Publishing corruption discussion: predatory journalism.

    PubMed

    Jones, James W; McCullough, Laurence B

    2014-02-01

    Dr Spock is a brilliant young vascular surgeon who is up for tenure next year. He has been warned by the chair of surgery that he needs to increase his list of publications to assure passage. He has recently had a paper reviewed by one of the top journals in his specialty, Journal X-special, with several suggestions for revision. He received an e-mail request for manuscript submission from a newly minted, open access, Journal of Vascular Disease Therapy, which promises a quick and likely favorable response for a fee. What should be done? A. Send the paper to another peer reviewed journal with the suggested revisions. B. Resubmit the paper to Journal X-special. C. Submit to the online journal as is to save time. D. Submit to the online journal and another regular journal. E. Look for another job. PMID:24461869

  7. Our World: Journaling in Space

    NASA Video Gallery

    Learn how famous explorers, scientists and even NASA use journals and science notebooks to record observations about Our World. See why journaling is important on the International Space Station to...

  8. Can laboratory tholins mimic the chemistry producing Titan's aerosols? A review in light of ACP experimental results

    NASA Astrophysics Data System (ADS)

    Coll, P.; Navarro-González, R.; Szopa, C.; Poch, O.; Ramírez, S. I.; Coscia, D.; Raulin, F.; Cabane, M.; Buch, A.; Israël, G.

    2013-03-01

    The first results obtained by the ACP experiment onboard Huygens probe revealed that the main products obtained after thermolysis of Titan's collected aerosols, were ammonia (NH3) and hydrogen cyanide (HCN). Titan's aerosols, and their laboratory analogues named tholins, have been the subject of experimental or theoretical studies during the last four decades. These studies have been mainly devoted to understanding their origin and formation mechanisms, their physical, chemical and optical properties, and their role in the radiative equilibrium of the satellite. Before the arrival of the Cassini-Huygens mission, the dense layer of aerosols hid many aspects of the satellite's surface and precious information about its composition. If Titan's aerosols have been in the eye and mind of planetary scientists during such a long time, it is not surprising that a literature survey displays a good quantity of papers on aerosol analogues. With aerosol analogues we mean any material produced in a terrestrial laboratory under conditions that try to represent those of Titan's atmosphere. We present here a study aimed to understand the particularities of aerosol analogues synthesized in different laboratories around the world in order to determine some of their most representative chemical fingerprints and in some cases, to perform a direct comparison of the volatiles produced after a thermal treatment done in conditions similar to the ones used by the ACP experiment. From the information collected, we propose a broad classification of aerosol analogues highlighting the materials that can be more representative of Titan's aerosols in terms of their content of organic volatiles. We identify the laboratory analogs that best suit the ACP results; such identification is of prime importance to correctly predict the optical properties of Titan's aerosol and to accurately estimate their contribution in radiative equilibrium models and/or to assess their role in chemical reactions of

  9. Journalism in a Free Society.

    ERIC Educational Resources Information Center

    Edwards, Verne E., Jr.

    Broadcast and print journalism are interrelated in this book's coverage of the functions and status of the "fourth estate". A first part discusses journalism's magnitude and significance, with separate chapters offering a profile of the press, a discussion of the people's need to know, and a brief history of American journalism. The second part…

  10. Monopoly Power and Electronic Journals.

    ERIC Educational Resources Information Center

    Meyer, Richard W.

    1997-01-01

    Rising periodical prices and lagging library budgets have many academics hoping that scholarly print journals will migrate to online versions. Examines economic factors shaping the electronic journal market, emerging new electronic journals, access versus ownership, consortial purchasing, self-maintained infrastructures, elimination of tenure and…

  11. Scholastic Journalism Education: Benchmark 1982.

    ERIC Educational Resources Information Center

    Shenton, Stephen G-M.; Smith, Anne

    Noting that no institution listed in "Accredited Journalism and Mass Communications Education, 1981-82" offers a scholastic journalism or secondary education sequence accredited by the American Council on Education in Journalism and Mass Communications, a study was conducted to examine the courses in the sequences that were offered at the…

  12. Evaluation of OAS Education Journals.

    ERIC Educational Resources Information Center

    Leavitt, Howard B.; And Others

    An in-depth evaluation of four Organization of American States educational journals is presented. The journals, published for distribution among Latin American countries, were "Tecnologia Educativa", "Curriculum", "Educacion de Adultors", and "La Educacion". Assessment was made of the journals' mandates, implementation procedures, and managerial…

  13. AVERA Introduces New Research Journal

    ERIC Educational Resources Information Center

    Magisos, Joel H.; Finch, Curtis R.

    1976-01-01

    The article announces the publication of a new journal by the American Vocational Education Research Association called the "Journal of Vocational Education Research." The journal is devoted to disseminating the results of original investigations in vocational education. Information on subscription and manuscript submission procedures is included.…

  14. Computerized Guides to Journal Selection.

    ERIC Educational Resources Information Center

    Rada, Roy; And Others

    1987-01-01

    Designed to characterize journals as part of the selection process for journals to be included in an information retrieval database, two studies used bibliometric techniques to examine patterns of publishing and topic patterns and coverage, and a third developed a rule-based system to evaluate the qualities of a journal. (CLB)

  15. Agronomy Journal Turns One Hundred

    Technology Transfer Automated Retrieval System (TEKTRAN)

    During 2008 we celebrate the centennial anniversary of Agronomy Journal. Many people have certainly been influenced in some way by the vast amount of science published during the 100-year existence of the journal. Within the 100 volumes of Agronomy Journal there are more than 29,087 authors who publ...

  16. Pursuing the journal mission.

    PubMed

    Norko, Michael A; Griffith, Ezra E H; Coleman, Jacquelyn T

    2014-01-01

    The mission of The Journal of the American Academy of Psychiatry and the Law, as articulated in its Instructions for Authors, is to be a forum for the exchange of multidisciplinary ideas and thoughtful and respectful scholarly analyses related to the theory and practice of forensic psychiatry. Recent refinements of The Journal's structure and policy can be understood as an effort to articulate a vision for emphasizing vibrant exchange of diverse scholarly activities and ideas expressing the highest levels of professionalism and concern for the ethics of forensic psychiatry and publishing. In this article, we explore the challenges encountered in realizing that vision, including managing the tone and level of discourse, creating structure without inhibiting creativity, demonstrating respect for persons in the use of case report material, expanding and guiding the utilization of peer review, promoting the new voices of authors with less writing experience, defining conflicts of interest for publishing purposes, and maintaining editorial independence in the context of serving organizational needs. We illustrate these challenges with recent experiences, explicating the decisions of the senior editors in an effort to be transparent about The Journal's processes and to encourage feedback from our readers about the adequacy of these practices. PMID:25187280

  17. Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor

    SciTech Connect

    Chemler, Joseph A.; Buchholz, Tonia J.; Geders, Todd W.; Akey, David L.; Rath, Christopher M.; Chlipala, George E.; Smith, Janet L.; Sherman, David H.

    2012-08-10

    Germicidin synthase (Gcs) from Streptomyces coelicolor is a type III polyketide synthase (PKS) with broad substrate flexibility for acyl groups linked through a thioester bond to either coenzyme A (CoA) or acyl carrier protein (ACP). Germicidin synthesis was reconstituted in vitro by coupling Gcs with fatty acid biosynthesis. Since Gcs has broad substrate flexibility, we directly compared the kinetic properties of Gcs with both acyl-ACP and acyl-CoA. The catalytic efficiency of Gcs for acyl-ACP was 10-fold higher than for acyl-CoA, suggesting a strong preference toward carrier protein starter unit transfer. The 2.9 {angstrom} germicidin synthase crystal structure revealed canonical type III PKS architecture along with an unusual helical bundle of unknown function that appears to extend the dimerization interface. A pair of arginine residues adjacent to the active site affect catalytic activity but not ACP binding. This investigation provides new and surprising information about the interactions between type III PKSs and ACPs that will facilitate the construction of engineered systems for production of novel polyketides.

  18. Expression of Vibrio harveyi Acyl-ACP Synthetase Allows Efficient Entry of Exogenous Fatty Acids into the Escherichia coli Fatty Acid and Lipid A Synthetic Pathways

    PubMed Central

    Jiang, Yanfang; Morgan-Kiss, Rachael M.; Campbell, John W.; Chan, Chi Ho; Cronan, John E.

    2010-01-01

    Although the Escherichia coli fatty acid synthesis (FAS) pathway is the best studied type II fatty acid synthesis system, a major experimental limitation has been the inability to feed intermediates into the pathway in vivo because exogenously-supplied free fatty acids are not efficiently converted to the acyl-acyl carrier protein (ACP) thioesters required by the pathway. We report that expression of Vibrio harveyi acyl-ACP synthetase (AasS), a soluble cytosolic enzyme that ligates free fatty acids to ACP to form acyl-ACPs, allows exogenous fatty acids to enter the E. coli fatty acid synthesis pathway. The free fatty acids are incorporated intact and can be elongated or directly incorporated into complex lipids by acyltransferases specific for acyl-ACPs. Moreover, expression of AasS strains and supplementation with the appropriate fatty acid restored growth to E. coli mutant strains that lack essential fatty acid synthesis enzymes. Thus, this strategy provides a new tool for circumventing the loss of enzymes essential for FAS function. PMID:20028080

  19. "In the Interest of the Colored Boys": Christopher J. Atkinson, William T. Coleman, and the Extension of Boys' Clubs Services to African-American Communities, 1906-1931

    ERIC Educational Resources Information Center

    Savage, Carter Julian

    2011-01-01

    This paper details how African-American boys' club workers, their Clubs as well as their service to African-American youth, gained legitimacy within the Boys' Club Federation, now Boys & Girls Clubs of America (BGCA). Specifically, it illustrates what facilitated a predominantly urban, northeastern organization to begin opening Clubs for…

  20. eLearning: A Review of Internet-Based Continuing Medical Education

    ERIC Educational Resources Information Center

    Wutoh, Rita; Boren, Suzanne Austin; Balas, E. Andrew

    2004-01-01

    Introduction: The objective was to review the effect of Internet-based continuing medical education (CME) interventions on physician performance and health care outcomes. Methods: Data sources included searches of MEDLINE (1966 to January 2004), CINAHL (1982 to December 2003), ACP Journal Club (1991 to July/August 2003), and the Cochrane Database…

  1. Demand-controlled ventilation of an entertainment club

    SciTech Connect

    Atkinson, G.V.

    1997-12-31

    Entertainment clubs, nightclubs, theaters, restaurants, and coliseums, with their highly variable occupancy rate, are excellent candidates for demand-controlled ventilation. The dynamic thermal requirements of both heating and cooling, coupled with the need to control indoor air quality because of the large number of patrons who also may be smoking during the highest occupancy, provide an opportunity to integrate the temperature controls with an indoor air quality control system. Significant energy savings may be realized by controlling the ventilation of outdoor air to match the heating, cooling, and humidity requirements as well as maintaining acceptable indoor air quality. This paper describes a demand-controlled ventilation system that was installed in an entertainment club in Boise, Idaho, using a multigas indoor air quality sensor to measure the level of indoor air pollutants, which, when combined with a mixed-air temperature sensor to provide economizer cooling, introduces outdoor air at a rate required to adequately ventilate the space.

  2. The Supernova Club: Bringing Space Science to Urban Youths

    NASA Astrophysics Data System (ADS)

    Sakimoto, P. J.; Pettit, R.; Balsara, D.; Garnavich, P.

    2008-06-01

    The Supernova Club is an experiment aimed at bringing space science to youths, almost all African Americans, from the most severely disadvantaged areas of the South Bend, Indiana, region. It leverages the National Youth Sports Program (NYSP) that, in Summer 2007, brought 100 children, ages 10-16 and living at or below the poverty level, to the Notre Dame campus for a 4-week non-residential summer program. Six contact hours of space science instruction were added to the core curriculum of nutrition, physical fitness, and academic study. At summer's end, 13 high interest/high potential youths were selected to form ``The Supernova Club''-a year-round, after-school, weekly follow-up program.

  3. Literature circles book club for science and language arts

    NASA Astrophysics Data System (ADS)

    Bombard, Britain

    Students from an urban middle school participated in a Science Book Club for one semester using the literature circles format. These students voluntarily attended twice weekly lunch meetings, reading books that followed their Grade 7 science classes. Groups of three to six participants read the same text, each performing rotating jobs to improve group discussions during meetings. When a group completed a book, participants created a presentation to share what they learned with the other groups in the club and the researcher/teacher. This research measured gains in science content knowledge and language arts skills focusing on reading comprehension, and literary response and analysis. Gains were measured using pre-existing district benchmarks. An ANCOVA showed that while no gains were found in science content knowledge, there were gains in language arts in the areas of reading comprehension and literary response and analysis.

  4. Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

    PubMed Central

    2013-01-01

    3-Oxo-acyl-acyl carrier protein (ACP) reductase (FabG) plays a key role in the bacterial fatty acid synthesis II system in pathogenic microorganisms, which has been recognized as a potential drug target. FabG catalyzes reduction of a 3-oxo-acyl-ACP intermediate during the elongation cycle of fatty acid biosynthesis. Here, we report gene deletion experiments that support the essentiality of this gene in P. aeruginosa and the identification of a number of small molecule FabG inhibitors with IC50 values in the nanomolar to low micromolar range and good physicochemical properties. Structural characterization of 16 FabG-inhibitor complexes by X-ray crystallography revealed that the compounds bind at a novel allosteric site located at the FabG subunit–subunit interface. Inhibitor binding relies primarily on hydrophobic interactions, but specific hydrogen bonds are also observed. Importantly, the binding cavity is formed upon complex formation and therefore would not be recognized by virtual screening approaches. The structure analysis further reveals that the inhibitors act by inducing conformational changes that propagate to the active site, resulting in a displacement of the catalytic triad and the inability to bind NADPH. PMID:24015914

  5. In silico analysis and modeling of ACP-MIP–PilQ chimeric antigen from Neisseria meningitidis serogroup B

    PubMed Central

    Gholami, Mehrdad; Salimi Chirani, Alireza; Moshiri, Mona; Sedighi, Mansour; Pournajaf, Abazar; Tohidfar, Masoud; Irajian, Gholamreza

    2015-01-01

    Background: Neisseria meningitidis, a life-threatening human pathogen with the potential to cause large epidemics, can be isolated from the nasopharynx of 5–15% of adults. The aim of the current study was to evaluate biophysical and biochemical properties and immunological aspects of chimeric acyl-carrier protein-macrophage infectivity potentiator protein-type IV pilus biogenesis protein antigen (ACP-MIP-PilQ) from N. meningitidis serogroup B strain. Methods: Biochemical properties and multiple alignments were predicted by appropriate web servers. Secondary molecular structures were predicted based on Chou and Fasman, Garnier-Osguthorpe-Robson, and Neural Network methods. Tertiary modeling elucidated conformational properties of the chimeric protein. Proteasome cleavage and transporter associated with antigen processing (TAP) binding sites, and T- and B-cell antigenic epitopes, were predicted using bioinformatic web servers. Results: Based on our in silico and immunoinformatics analyses, the ACP-MIP-PilQ protein (AMP) can induce high-level cross-strain bactericidal activity. In addition, several immune proteasomal cleavage sites were detected. The 22 epitopes associated with MHC class I and class II (DR) alleles were confirmed in the AMP. Thirty linear B-cell epitopes as antigenic regions were predicted from the full-length protein. Conclusion: All predicted properties of the AMP indicate it could be a good candidate for further immunological in vitro and in vivo studies. PMID:26989750

  6. Benzodiazepine dependence among multidrug users in the club scene

    PubMed Central

    Kurtz, Steven P.; Surratt, Hilary L.; Levi-Minzi, Maria A.; Mooss, Angela

    2011-01-01

    Background Benzodiazepines (BZs) are among the most frequently prescribed drugs with the potential for abuse. Young adults ages 18–29 report the highest rates of BZ misuse in the United States. The majority of club drug users are also in this age group, and BZ misuse is prevalent in the nightclub scene. BZ dependence, however, is not well documented. This paper examines BZ dependence and its correlates among multidrug users in South Florida’s nightclub scene. Methods Data were drawn from structured interviews with men and women (N=521) who reported regular attendance at large dance clubs and recent use of both club drugs and BZs. Results Prevalences of BZ-related problems were 7.9% for BZ dependence, 22.6% BZ abuse, and 25% BZ abuse and/or dependence. In bivariate logistic regression models, heavy cocaine use (OR 2.27; 95% CI 1.18, 4.38), severe mental distress (OR 2.63; 95% CI 1.33, 5.21), and childhood victimization history (OR 2.43; 95% CI 1.10, 5.38) were associated with BZ dependence. Heavy cocaine use (OR 2.14; 95% CI 1.10, 4.18) and severe mental distress (OR 2.16; 95% CI 1.07, 4.37) survived as predictors in the multivariate model. Discussion BZ misuse is widespread among multidrug users in the club scene, who also exhibit high levels of other health and social problems. BZ dependence appears to be more prevalent in this sample than in other populations described in the literature. Recommendations for intervention and additional research are described. PMID:21708434

  7. Algorithmic Procedure for Finding Semantically Related Journals.

    ERIC Educational Resources Information Center

    Pudovkin, Alexander I.; Garfield, Eugene

    2002-01-01

    Using citations, papers and references as parameters a relatedness factor (RF) is computed for a series of journals. Sorting these journals by the RF produces a list of journals most closely related to a specified starting journal. The method appears to select a set of journals that are semantically most similar to the target journal. The…

  8. SciTech Clubs for Girls. [Annual] technical report

    SciTech Connect

    Nogal, A.M.

    1993-02-01

    Since January 1992, 9 exhibits have been constructed by the SciTech Clubs for Girls, which involved 63 girls, ages 10 to 14. These exhibits are: Bubble Shapes by the St. Charles Cadette Girl Scout Troop No. 109. Density Games by the South Elgin Cadette Girl Scout Troop No. 132. Electric Fleas by the Warrenville Junior Girl Scout Troop No. 305. Energy vs. Power by the Aurora Junior Girl Scout Troop No. 242. The Organ Pipe by the Bartlett Junior Girl Scout Troop No. 107. Ohm`s Law by the Geneva Junior Girl Scout Troop No. 401. What is Gravity by the Pilsen YMCA girls. Insulation at Work by the Algonquin Junior Girl Scout Troop No. 303. Series vs. Parallel by the Leland Junior Girl Scout Troop No. 50. The report is a description of each exhibit and the group that built the exhibit. Each group had a minimum of 10 hours of contact time at SciTech with the SciTech Clubs for Girls Program Coordinator. All mentors are female. Each exhibit building experience includes a trip to the hardware store to purchase supplies. After the exhibit is complete, the girls receive certificates of achievement and a SciTech Club Patch.

  9. [Club drugs: old medicines as new party drugs].

    PubMed

    Abanades, Sergio; Peiró, Ana M; Farré, Magí

    2004-09-11

    During the last few years the term club drugs has been used for defining an heterogeneous group of chemical substances in permanent evolution, that are consumed for recreational purposes. These substances have been extensively used, firstly by the Rave culture and later by the so called Club culture. These movements are characterized by the search of amplified sensations, by means of the combination of electronic music, marathon dancing and substance abuse. After years with a predominating consumption of designer amphetamines in these groups, it seems that the use of another type of substances is increasing, fundamentally drugs with hallucinogenic effects. This review focus in four of these substances; ketamine, dextromethorphan, nitrous oxide and gamma-hydroxybutyric acid (GHB, liquid ecstasy), and includes a discussion of their pharmacology, recreational use, adverse effects and patient management. These drugs are, at he same time, drugs of abuse and medicines with concrete indications in therapeutics, with an important increase of their consumption in the last few years. The Rave and Club cultures are also described. PMID:15373979

  10. New NAS journal

    NASA Astrophysics Data System (ADS)

    In April 1984 the National Academy of Sciences (NAS) will begin publishing a new quarterly focusing on science policy. Written primarily for legislators, diplomats, corporate managers, security analysts, and other public policy analysts, the new journal will deal with such diverse topics as arms control, economic competition, social change, and health care.Original articles are expected to create a 120-page periodical that will discuss policy issues on a sophisticated but nonspecialist level, in a manner similar to that which Foreign Affairs uses to discuss U.S. foreign policy topics, according to NAS.

  11. New Journal Editors Appointed

    NASA Astrophysics Data System (ADS)

    Major, Barbara

    2009-11-01

    New editors have been appointed for Geophysical Research Letters (GRL), Journal of Geophysical Research (JGR)-Solid Earth, Reviews of Geophysics, JGR-Space Physics, Paleoceanography, and Tectonics. At GRL, new editors Noah Diffenbaugh (Stanford University, Stanford, Calif.), Paolo D’Odorico (University of Virginia, Charlottesville), Ruth Harris (U.S. Geological Survey (USGS), Menlo Park, Calif.), Wolfgang Knorr (University of Bristol, Bristol, UK), Geoffrey Tyndall (National Center for Atmospheric Research, Boulder, Colo.), and Michael Wysession (Washington University, St. Louis, Mo.) have joined Editor-in-Chief Eric Calais and other editors Margaret Chen, Fabio Florindo, Anne Müller, Nikolai Ostgaard, Eric Rignot, and Meric Srokosz.

  12. The Journal Microarrays

    PubMed Central

    Lin, Shu-Kun

    2011-01-01

    Our publishing company MDPI AG has its headquarters in Basel, Switzerland where there are thousands of scientists working in the laboratories of pharmaceutical companies and institutes including Novartis [1], F. Hoffmann-La Roche [2] and institutes affiliated with University of Basel [3]. In 1996, the first annual microplate conference MipTec was held in Basel, and the MipTec 2011 was held a few days ago in Basel [4]. I published a paper on microplate standardization presented at MipTec 1996 in MDPI’s longest-running journal Molecules [5-7]. [....

  13. Comparing the hydrology journals

    NASA Astrophysics Data System (ADS)

    McDonnell, Jeff

    How do the various water resources journals stack up? This question is frequently asked at scientific meetings, within promotion and tenure committees, and around graduate student lunch counters. Several years ago G. Dagan (Eos, June 20,1989) published a very useful report of findings by the Institute for Scientific Information (ISI), which publishes annual reviews of scientometric indices. I read his report just after receiving my Ph.D., and the numbers greatly influenced my choice of where to publish my dissertation. For those graduate students and water resources professionals who may benefit from the latest figures, I report my compilation of the 1995 impact factors from ISI.

  14. Reflective journaling: developing an online journal for distance education.

    PubMed

    Kessler, Penny D; Lund, Carole H

    2004-01-01

    Reflective journal writing can be a useful heuristic tool to foster critical thinking skills and develop reflective clinical practice in nursing. When combined with a distance education delivery format, the online journal helps to leverage the strengths of reflective learning with educational technology as well as provide a seamless record of learning outcomes across the curriculum. The authors discuss the incorporation of an online reflective journal into a distance education clinical course and provide guidelines for educators considering a similar approach. PMID:14726795

  15. The youth sports club as a health-promoting setting: An integrative review of research

    PubMed Central

    Quennerstedt, Mikael; Eriksson, Charli

    2013-01-01

    Aims: The aims of this review is to compile and identify key issues in international research about youth sports clubs as health-promoting settings, and then discuss the results of the review in terms of a framework for the youth sports club as a health-promoting setting. Methods: The framework guiding this review of research is the health-promoting settings approach introduced by the World Health Organization (WHO). The method used is the integrated review. Inclusion criteria were, first, that the studies concerned sports clubs for young people, not professional clubs; second, that it be a question of voluntary participation in some sort of ongoing organized athletics outside of the regular school curricula; third, that the studies consider issues about youth sports clubs in terms of health-promoting settings as described by WHO. The final sample for the review consists of 44 publications. Results: The review shows that youth sports clubs have plentiful opportunities to be or become health-promoting settings; however this is not something that happens automatically. To do so, the club needs to include an emphasis on certain important elements in its strategies and daily practices. The youth sports club needs to be a supportive and healthy environment with activities designed for and adapted to the specific age-group or stage of development of the youth. Conclusions: To become a health-promoting setting, a youth sports club needs to take a comprehensive approach to its activities, aims, and purposes. PMID:23349167

  16. Practical Ideas for Teaching Journalism.

    ERIC Educational Resources Information Center

    Bustrum, Dwight, Ed.; Hallenbeck, Carol, Ed.; Rittger, Alison, Ed.

    A "how-to" book for advisers looking for creative and contemporary ways to teach journalism, this book can be a single source for a journalism class or a supplement to any high school journalism text. The book concentrates on teaching methods as well as subject matter--it tells teachers what to do and how to do it, what to say and what to write on…

  17. Nineteenth Century Medical Journalism in Texas: With a Journal Checklist *

    PubMed Central

    Baird, Violet M.

    1972-01-01

    Texas medical journals prior to 1900 have been incompletely (sometimes incorrectly) recorded in periodical checklists. This paper attempts to provide a short account of the purposes and achievements of the more significant journals and to list all names and related name changes, in so far as it has been possible to do so. PMID:4559906

  18. Style in medical journals.

    PubMed Central

    Adams Smith, D E

    1983-01-01

    A study of medical journals from 1962 showed a constant preoccupation with style. Editors and contributors on both sides of the Atlantic revile unnecessary obscurity and complexity and the use of jargon, barbarisms, vogue words, and weak impersonal constructions. They bewail the pompous use of verbiage and the "medspeak" typified by acronyms and neologisms created by affixation. Suggestions for possible causes of poor medical style range from editorial demands for compression and a general ignorance of the principles of good writing to faulty logic and the subordination of communication to status seeking. The consequences of bad writing may include the fragmentation of knowledge, an increase in the importance of abstracting services, a trend towards free glossy medical newspapers, and, as remedial measures, workshops and courses in medical writing. Some implications for English language teachers working with foreign medical graduates and preclinical students are discussed. PMID:6414596

  19. Campylobacter jejuni fatty acid synthase II: Structural and functional analysis of [beta]-hydroxyacyl-ACP dehydratase (FabZ)

    SciTech Connect

    Kirkpatrick, Andrew S.; Yokoyama, Takeshi; Choi, Kyoung-Jae; Yeo, Hye-Jeong

    2009-08-14

    Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making FAS II enzymes excellent targets for antibiotics discovery. The {beta}-hydroxyacyl-ACP dehydratase (FabZ) catalyzes an essential step in the FAS II pathway. Here, we report the structure of Campylobacter jejuni FabZ (CjFabZ), showing a hexamer both in crystals and solution, with each protomer adopting the characteristic hot dog fold. Together with biochemical analysis of CjFabZ, we define the first functional FAS II enzyme from this pathogen, and provide a framework for investigation on roles of FAS II in C. jejuni virulence

  20. Cloning of Acyl-ACP Thioesterase FatA from Arachis hypogaea L. and Its Expression in Escherichia coli

    PubMed Central

    Chen, Gao; Peng, Zhen-ying; Shan, Lei; Xuan, Ning; Tang, Gui-ying; Zhang, Yan; Li, Lan; He, Qing-fang; Bi, Yu-ping

    2012-01-01

    In this study, a full-length cDNA of the acyl-ACP thioesterase, AhFatA, was cloned from developing seeds of Arachis hypogaea L. by 3′-RACE. Sequence analysis showed that the open reading frame encodes a peptide of 372 amino acids and has 50–70% identity with FatA from other plants. Real-time quantitative PCR analysis revealed that AhFatA was expressed in all tissues of A. hypogaea L., but most strongly in the immature seeds harvested at 60 days after pegging. Heterologous expression of AhFatA in Escherichia coli affected bacterial growth and changed the fatty acid profiles of the membrane lipid, resulting in directed accumulation towards palmitoleic acid and oleic acid. These results indicate that AhFatA is at least partially responsible for determining the high palmitoleic acid and oleic acid composition of E. coli. PMID:23093853

  1. X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv

    SciTech Connect

    Dyer, David H.; Lyle, Karen S.; Rayment, Ivan; Fox, Brian G.

    2010-07-13

    Genome sequencing showed that two proteins in Mycobacterium tuberculosis H37Rv contain the metal binding motif (D/E)X{sub 2}HX{sub {approx}100}(D/E)X{sub 2}H characteristic of the soluble diiron enzyme superfamily. These putative acyl-ACP desaturase genes desA1 and desA2 were cloned from genomic DNA and expressed in Escherichia coli BL21(DE3). DesA1 was found to be insoluble, but in contrast, DesA2 was a soluble protein amenable to biophysical characterization. Here, we report the 2.0 {angstrom} resolution X-ray structure of DesA2 determined by multiple anomalous dispersion (MAD) phasing from a Se-met derivative and refinement against diffraction data obtained on the native protein. The X-ray structure shows that DesA2 is a homodimeric protein with a four-helix bundle core flanked by five additional helices that overlay with 192 structurally equivalent amino acids in the structure of stearoyl-ACP {Delta}9 desaturase from castor plant with an rms difference 1.42 {angstrom}. In the DesA2 crystals, one metal (likely Mn from the crystallization buffer) was bound in high occupancy at the B-site of the conserved metal binding motif, while the A-site was not occupied by a metal ion. Instead, the amino group of Lys-76 occupied this position. The relationships between DesA2 and known diiron enzymes are discussed.

  2. Crystallization and preliminary X-ray crystallographic analysis of enoyl-ACP reductase III (FabL) from Bacillus subtilis

    SciTech Connect

    Kim, Kook-Han; Park, Joon Kyu; Ha, Byung Hak; Moon, Jin Ho; Kim, Eunice EunKyeong

    2007-03-01

    Enoyl-ACP reductase III (FabL) from B. subtilis has been overexpressed, purified and crystallized. The crystal belongs to space group P622, with unit-cell parameters a = b = 139.56, c = 62.75 Å, α = β = 90, γ = 120°, and data were collected to 2.5 Å resolution using synchrotron radiation. Enoyl-[acyl-carrier protein] reductase (enoyl-ACP reductase; ENR) is a key enzyme in type II fatty-acid synthase that catalyzes the last step in each elongation cycle. It has been considered as an antibiotic target since it is an essential enzyme in bacteria. However, recent studies indicate that some pathogens have more than one ENR. Bacillus subtilis is reported to have two ENRs, namely BsFabI and BsFabL. While BsFabI is similar to other FabIs, BsFabL shows very little sequence similarity and is NADPH-dependent instead of NADH-dependent as in the case of FabI. In order to understand these differences on a structural basis, BsFabL has been cloned, expressed and and crystallized. The crystal belongs to space group P622, with unit-cell parameters a = b = 139.56, c = 62.75 Å, α = β = 90, γ = 120° and one molecule of FabL in the asymmetric unit. Data were collected using synchrotron radiation (beamline 4A at the Pohang Light Source, Korea). The crystal diffracted to 2.5 Å resolution.

  3. Effect of a mutagenized acyl-ACP thioesterase FATA allele from sunflower with improved activity in tobacco leaves and Arabidopsis seeds.

    PubMed

    Moreno-Pérez, Antonio Javier; Venegas-Calerón, Mónica; Vaistij, Fabián E; Salas, Joaquin J; Larson, Tony R; Garcés, Rafael; Graham, Ian A; Martínez-Force, Enrique

    2014-03-01

    The substrate specificity of the acyl-acyl carrier protein (ACP) thioesterases significantly determines the type of fatty acids that are exported from plastids. Thus, designing acyl-ACP thioesterases with different substrate specificities or kinetic properties would be of interest for plant lipid biotechnology to produce oils enriched in specialty fatty acids. In the present work, the FatA thioesterase from Helianthus annuus was used to test the impact of changes in the amino acids present in the binding pocket on substrate specificity and catalytic efficiency. Amongst all the mutated enzymes studied, Q215W was especially interesting as it had higher specificity towards saturated acyl-ACP substrates and higher catalytic efficiency compared to wild-type H. annuus FatA. Null, wild type and high-efficiency alleles were transiently expressed in tobacco leaves to check their effect on lipid biosynthesis. Expression of active FatA thioesterases altered the composition of leaf triacylglycerols but did not alter total lipid content. However, the expression of the wild type and the high-efficiency alleles in Arabidopsis thaliana transgenic seeds resulted in a strong reduction in oil content and an increase in total saturated fatty acid content. The role and influence of acyl-ACP thioesterases in plant metabolism and their possible applications in lipid biotechnology are discussed. PMID:24327259

  4. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2007-2008 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2008

    2008-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its nine staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by …

  5. A comparison of surface roughness after micro abrasion of enamel with and without using CPP-ACP: An in vitro study

    PubMed Central

    Mathias, Jones; Kavitha, S; Mahalaxmi, S

    2009-01-01

    Aim: The aim of this study was to evaluate the surface roughness of enamel after micro abrasion with and without using remineralization agent, CPP-ACP (Casein Phosphopeptide-Amorphous Calcium Phosphate). Materials and Methods: Thirty freshly extracted anterior teeth were collected. The samples were randomly assigned to two study and one control group. Group A (n = 10) containing teeth in which only micro abrasion was done, Group B (n = 10) containing teeth in which CPP-ACP (G C Tooth Mousse) was applied after micro abrasion for a period of 30 days, once daily for three minutes and Group C (n = 10) in which no preparation was done and which acted as the control group. The samples were stored in artificial saliva and evaluated after 30 days, using surface profilometer. The results were tabulated and statistically analyzed. Results: According to the results of this study, a combination of the micro abrasion procedure and CPP-ACP application reduced the enamel surface roughness significantly, when compared to micro abrasion done alone. Conclusion: Application of CPP-ACP after micro abrasion procedure significantly reduces the enamel surface roughness thereby decreasing the risk of caries. PMID:20379436

  6. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2008-2009 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2009

    2009-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its eight staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  7. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2009-2010 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2010

    2010-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its five staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by Commissioners…

  8. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. Arizona Commission for Postsecondary Education (ACPE) Fiscal Year 2005-2006 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2006

    2006-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5-year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its seven staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  9. Enhanced free fatty acid production by codon-optimized Lactococcus lactis acyl-ACP thioesterase gene expression in Escherichia coli using crude glycerol.

    PubMed

    Lee, Sunhee; Park, Soohyun; Park, Chulhwan; Pack, Seung Pil; Lee, Jinwon

    2014-12-01

    Fatty acid production and composition are determined by the type of acyl-acyl carrier protein thioesterases (acyl-ACP TEs) expressed in Escherichia coli. Bacterial acyl-ACP TEs from Lactococcus lactis (SGJS47), Enterococcus faecalis (SGJS49), and Burkholderia cepacia (SGJS50) were codon-optimized and expressed in E. coli for enhanced fatty acid production. Samples were extracted at the lag, log, and stationary phases of cell growth, and gene expression levels of the codon optimized acy-ACP TEs as well as fatty acid production were monitored. At 24h after initiation of gene expression, the OPLlTE expression level and fatty acid production in SGJS47 increased up to 15.8-fold and 3.2-fold compared to the control and other recombinant strains, respectively. Additionally, in SGJS47, improvement in free fatty acid (FFA) composition, high-specificity production of short-chain fatty acids (C8, C10) and unsaturated fatty acids (C16:1) was achieved in crude glycerol medium condition. Compared with control strain, the percentage of FFAs (C8 and C10) was enhanced by approximately 16- to 21-fold, C16:1 FFA ratio increased approximately 18-fold. Observation of codon-optimized acyl-ACP TE genes expression level in E. coli may be useful for understanding mechanisms towards improving fatty acid production. Engineered strains have the potential to overproduce specific FFAs and thereby reduce the cost of fatty acid production by using industrially inexpensive carbon sources. PMID:25442943

  10. Morphological and metabolic changes in transgenic wheat with altered glycerol-3-phosphate acyltransferase or acyl-acyl carrier protein (ACP) thioesterase activities.

    PubMed

    Edlin, D A; Kille, P; Wilkinson, M D; Jones, H D; Harwood, J L

    2000-12-01

    We have transformed varieties of wheat with a Pisum sativum glycerol-3-phosphate acyltransferase gene, and also with an Arabidopsis thaliana acyl-ACP thioesterase gene. Morphological (growth, organelle development) and metabolic changes (fatty acid labelling of chloroplast and non-chloroplast lipids) have been observed in transgenics with altered gene expression for either enzyme. PMID:11171169

  11. Expanding Access and Increasing Success in Postsecondary Education for Arizonans. The Arizona Commission for Postsecondary Education (ACPE) 2006-2007 Annual Report

    ERIC Educational Resources Information Center

    Arizona Commission for Postsecondary Education, 2007

    2007-01-01

    The work of the Arizona Commission for Postsecondary Education (ACPE) is guided by a 5 year strategic plan. The purpose of the plan is to provide focus for the activity of this small agency and its eight staff members in order to increase productivity and impact in the areas of its statutory authority. The mission and goals were accepted by…

  12. Primary Journal Literature of Physics.

    ERIC Educational Resources Information Center

    Cooper, Marianne; Thayer, Candace W.

    Four hundred and ninety one primary journals covered by "Physics Abstracts" in 1965 have been studied and their basic characteristics analyzed in terms of sponsorship, distribution by country, language, frequency, and coverage by secondary services other than "Physics Abstracts," and the number of libraries holding each journal. (Author)

  13. Humanities Journals Confront Identity Crisis

    ERIC Educational Resources Information Center

    Howard, Jennifer

    2009-01-01

    Senior scholars, the A-list of academic publishing, seem to submit fewer unsolicited manuscripts to traditional humanities journals than they used to. The journal has become, with very few exceptions, the place where junior and midlevel scholars are placing their work. Technology and changing habits have called into question the nature of the…

  14. Alabama Counseling Association Journal, 1996.

    ERIC Educational Resources Information Center

    Farrell, R. Joel, II, Ed.

    1996-01-01

    This document consists of the two issues of the "Alabama Counseling Association Journal" published during 1996. The focus of the journal is on communicating ideas and information that will help counselors to implement the counseling role and develop the profession of counseling. Issue number 1 includes the following articles: "Commitment through…

  15. Japan Studies Association Journal, 1998.

    ERIC Educational Resources Information Center

    Speaker, Richard B., Jr., Ed.; Kawada, Louise Myers, Ed.

    1998-01-01

    This journal presents new perspectives and materials on Japan that are engaging, relatively jargon-free, and shaped so that their usefulness in a college classroom is readily apparent. The journal represents an example of the potential for genuine scholarship that lies within interdisciplinary studies. Articles are divided among three thematic…

  16. Astronomy & Astrophysics: an international journal

    NASA Astrophysics Data System (ADS)

    Bertout, C.

    2011-07-01

    After a brief historical introduction, we review the scope, editorial process, and production organization of A&A, one of the leading journals worldwide dedicated to publishing the results of astrophysical research. We then briefly discuss the economic model of the Journal and some current issues in scientific publishing.

  17. Local Evaluation of Chemistry Journals

    ERIC Educational Resources Information Center

    Kraus, Joseph R.; Hansen, Rachel

    2008-01-01

    This paper reports on the evaluation of local usage statistics of a specific set of chemistry journals at the University of Denver in Colorado, USA. The objective of the study is to demonstrate that commercial publishers in chemistry charge considerably more for their journals than those from the non-commercial sector. There are three variables…

  18. THE Journal's 2007 Innovators: 1

    ERIC Educational Resources Information Center

    T.H.E. Journal, 2007

    2007-01-01

    Through a variety of efforts large and small, across schools, districts, and even oceans, educators are making teaching and learning alive through the pioneering use of technology. Together, they are "T.H.E. Journal"'s class of 2007 Innovators. This article presents the class of 2007 Innovators along with their profiles. They are: (1) Edith…

  19. Abstract Journal Concept Being Examined

    ERIC Educational Resources Information Center

    Somerville, Brendan F.

    1972-01-01

    In order to control the information explosion, some European chemical groups are studying the idea of abandoning full publication in printed form of all primary journals and, in their place, substituting a new form of abstract journal combined with a microfilm record of full scientific papers. (Author/CP)

  20. The Urbanization of American Journalism.

    ERIC Educational Resources Information Center

    Nord, David Paul

    1992-01-01

    Discusses the changes in journalism occurring during the growth of private enterprise in the United States. Focuses on newspapers in Chicago and other midwestern cities. Describes Joseph Pulitzer's "New York World" as the culmination of the urbanization of U.S. journalism, recognizing the development of public interdependence in a private world.…

  1. Let Us Rank Journalism Programs

    ERIC Educational Resources Information Center

    Weber, Joseph

    2014-01-01

    Unlike law, business, and medical schools, as well as universities in general, journalism schools and journalism programs have rarely been ranked. Publishers such as "U.S. News & World Report," "Forbes," "Bloomberg Businessweek," and "Washington Monthly" do not pay them much mind. What is the best…

  2. Journalism and Institutional Review Boards

    ERIC Educational Resources Information Center

    Dash, Leon

    2007-01-01

    The author opposes any Institutional Review Boards (IRBs) overseeing the work of journalism professors and journalism students in any academic institution. He argues that the tendency for IRBs to require anonymity for persons interviewed immediately reduces the credibility of any journalistic story. The composition of an IRB is questioned on…

  3. Student Journal Writing in Science.

    ERIC Educational Resources Information Center

    Ediger, Marlow

    Journal writing in science can be productive and stress basic skills. Students need to be highly motivated to engage in journal writing, and since the world of science fascinates most learners, chances for motivation are good. The subject matter to be written about needs to relate directly to the ongoing unit of study. Dramatizations, both formal…

  4. Military Market Exclusive Club Or Major Market Opportunity?

    NASA Astrophysics Data System (ADS)

    Morrow, Dan

    1988-06-01

    The topic the title is Military Market - An Exclusive Club or Major Market Opportunity? I think it really depends on your specific product. I know a lot of people view the military as being an exclusive club. I think some of the people who have had the opportunity to see Morely Safer and the 60 Minutes crew come into their office and talk to them about 600 toilet seat really wish they weren't members of that exclusive club. But I have worked in the military area, where I am kind of complementing what Dr. Ionson had to present earlier, except I am kind of on the other side of the fence. I have been a defense contractor for 11 years, so I have a little bit different point of view than the government does. But a lot of what I am saying tends to be a near-term market kind of approach rather than a longer-term sort of product development kind of information. But there certainly is, you are right, a lot of money in the government. This year's military budget is about 290 billion dollars, on the order of $80 billion of that goes into buying things. So there is a lot of money out there. What I am going to be talking about today is how much of that money goes into lasers. I am going to try to quantify it and also give a little bit of a qualitative estimate of where the trends are going, what is going to be the next lasers to be bought.

  5. Journal Evaluation: Technical and Practical Issues.

    ERIC Educational Resources Information Center

    Rousseau, Ronald

    2002-01-01

    Provides an overview of journal evaluation indicators, highlighting strengths and weaknesses and their range of applicability. Topics include the definition of a quality journal; different notions of impact factors; citation models; electronic journals; ranking journals; possible biases in citation databases; and using the journal impact in…

  6. 78 FR 13086 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Job Clubs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ...; Job Clubs Study ACTION: Notice. SUMMARY: The Department of Labor (DOL), as part of its continuing... CFBNP@dol.gov . SUPPLEMENTARY INFORMATION: I. Background Over the past several decades, job search support groups, commonly referred to as ``job clubs'' have evolved into one of several...

  7. The Kids' Book Club: Lively Reading and Activities for Grades 1-3.

    ERIC Educational Resources Information Center

    Webber, Desiree; Shropshire, Sandy

    Children learn to love reading by sharing quality books. Intended for children's librarians, media specialists, teachers, day care providers, and parents, this book will make it easy and fun to conduct book club meetings with little preparation time. Everything needed to start a weekly book club at school or at the library is included--detailed…

  8. Lessons of Researcher-Teacher Co-Design of an Environmental Health Afterschool Club Curriculum

    ERIC Educational Resources Information Center

    Hundal, Savreen; Levin, Daniel M.; Keselman, Alla

    2014-01-01

    This paper addresses the impact of teachers' beliefs about argumentation and their community of practice framed views of teaching on co-designing an environmental health afterschool club curriculum with researchers. Our team collaborated with a group of four middle school teachers, asking them to co-design a club that would facilitate (1)…

  9. Self-Esteem Profile among the Female Futsal-Football Players at Jordanian Clubs

    ERIC Educational Resources Information Center

    Khasawneh, Aman

    2015-01-01

    This study aimed at identifying the level of physical and body self-esteem among the female futsal - football players at Jordanian clubs. The sample of the study was composed of (38) female players among the Jordanian clubs' players of futsal-football who were chosen randomly out of the study community, and the self-esteem scale was used,…

  10. A Leesburg, Virginia, Service Club Introduces Lithuanian Communities to American Institutions.

    ERIC Educational Resources Information Center

    Raflo, Alan

    1993-01-01

    Describes how Kiwanis club members in Leesburg, Virginia, organized a successful trip to two Lithuanian communities without government support. U.S. visitors spoke to Lithuanians about the role of small businesses and civic clubs in the United States. Possible outcomes of the trip include continuing connections between businesses and between…

  11. Engaging the Disengaged: Using Learning Clubs to Motivate Struggling Adolescent Readers and Writers

    ERIC Educational Resources Information Center

    Casey, Heather K.

    2008-01-01

    This article describes a seventh grade teacher's use of learning clubs to motivate struggling students to engage in literacy events and foster literacy development. The data suggests the evolution of these learning clubs in this teacher's classroom is organic, emerging in response to the unique literacy needs of the students in this urban setting.…

  12. Benefits of Job Clubs for Executive Job Seekers: A Tale of Hares and Tortoises

    ERIC Educational Resources Information Center

    Kondo, Christopher T.

    2009-01-01

    This qualitative research study compares the experiences of 2 groups of executive job seekers--job club members and nonmembers--through thematic analysis of open-ended interviews. The findings indicated that job club members benefited from group learning, increased accountability, networking opportunities, emotional support, helping other members,…

  13. A study on the relationship between commitment of club activity and vocational readiness among university students.

    PubMed

    Mizusawa, Takashi; Hochi, Yasuyuki; Mizuno, Motoki

    2012-01-01

    The purpose of this study was to clarify the relationship between commitment of club activities and the vocational readiness among juniors at university. In this study, organizational commitment questionnaire (Mowday, 1979) and vocational readiness scale (Wakabayashi, Goto, and Shinkai, 1983) were tested with 178 (120 men, 58 women) juniors at one physical education university in the metropolitan area. According to correlation analysis, the relation between commitment of club activities and the vocational readiness was positive significant correlation (r = .303, p < .01). Moreover, we executed t-test. As the combined results, this study provided the following three conclusions; 1) Vocational readiness score of students who belonged to the club were higher than that of other students. 2) Vocational readiness score of students who were committed to club activities were higher than that of students with low commitment to club activities. 3) Students who were committed to club activities tended to increase the score of vocational readiness. It was not able to be declared that there were positive influences of the club activities in university education from the viewpoint of vocational readiness acquisition. Therefore, it is necessary to consider what the club activities should be from the viewpoint of university student's career education. PMID:22317677

  14. Authentic Science Research in Elementary School After-School Science Clubs

    ERIC Educational Resources Information Center

    Feldman, Allan; Pirog, Kelly

    2011-01-01

    In this paper we report on teachers' and students' participation in authentic science research in out of school time science clubs at elementary schools. In the program four to five teachers worked alongside practicing scientists as part of their research groups. Each teacher facilitated a club with 10-15 students who, by extension, were members…

  15. The Washington Biologists' Field Club: Its Members and Its History (1900-2006)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This short paper is a review of book that outlines the 100-year history of the Washington Biologists' Field Club. The Club has had 267 members in its history from 1900-2006, several of which have been noted entomologists. Biographies (or autobiographies) are presented for each member, along with b...

  16. Comprehension Right from the Start: How To Organize and Manage Book Clubs for Young Readers.

    ERIC Educational Resources Information Center

    Marriott, Donna

    Noting that book clubs offer a balanced approach that respects the highly individualized nature of learning and utilizes guided reading, shared reading, listening, speaking, writing, and critical thinking skills, this book proposes how to organize and manage book clubs for young readers. The book provides suggestions on how to accomplish the…

  17. "The Text Opened My Eyes": A Book Club on Teaching Writing to ELLs

    ERIC Educational Resources Information Center

    Andrei, Elena; Ellerbe, Marcie; Cherner, Todd

    2015-01-01

    This qualitative study looked at a book club for US teachers in public schools focused on teaching writing to English language learners (ELLs). To guide the study, the central research questions were: (1) What are teachers' perceptions about a book club professional development experience?; and (2) How are teachers' views about second language…

  18. Attitudes of Overweight and Normal Weight Adults Regarding Exercise at a Health Club

    ERIC Educational Resources Information Center

    Miller, Wayne C.; Miller, Todd A.

    2010-01-01

    Objective: To compare attitudes of overweight (OW) and normal weight (NW) adults regarding health club exercise. Design: A 46-item survey (23 pairs of attitude/value statements) measured attitudes toward exercising at a health club 30 minutes, twice a week, for a month. Setting: Survey posted on surveymonkey.com. Respondents (men = 730, women =…

  19. The Clio Club: An Extracurricular Model for Elementary Social Studies Enrichment

    ERIC Educational Resources Information Center

    Morris, Ronald V.

    2005-01-01

    Each year, about 70 4th- and 5th-grade students from an elementary school in an Indiana urban area participate in an extracurricular social studies enrichment program called the Clio Club. Clio is derived from the Greek muse of history, and the club offers a variety of activities to help students discover and interpret social studies beyond the…

  20. The Women's National Press Club: Case Study in the Professionalization of Women Journalists.

    ERIC Educational Resources Information Center

    Beasley, Maurine H.

    The Women's National Press Club (WNPC) existed in Washington, D.C., from 1919 to 1971 primarily because the National Press Club (NPC) refused to admit women. The WNPC offered mutual support in the face of male hostility. Women were virtually cut off from news sources; 20 women had Capitol press gallery privileges in 1879, but they were effectively…

  1. 75 FR 23587 - Annual Seattle Yacht Club's “Opening Day” Marine Parade

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ..., 1989 issue of the Federal Register (54 FR 19167). Under the provisions of 33 CFR 100.1304, the... SECURITY Coast Guard 33 CFR Part 100 Annual Seattle Yacht Club's ``Opening Day'' Marine Parade AGENCY... Seattle Yacht Club's ``Opening Day'' Marine Parade from 8 a.m. through 6 p.m. on May 2, 2010. This...

  2. Evaluation of Students' Perceptions about Efficiency of Educational Club Practices in Primary Schools

    ERIC Educational Resources Information Center

    Gelen, Ismail; Onay, Ihsan; Varol, Volkan

    2014-01-01

    The purpose of this study is to examine the efficiency of "Educational Club Practices" that has been in Elementary School program since 2005-2006, by examining the attitudes of students about "Educational Club Practices". Sample was selected in two steps. First, stratified sampling was employed and then random sampling was…

  3. Self-Capacitating Activities of Mothers' Clubs of Primarily Indigenous Membership in Bolivia.

    ERIC Educational Resources Information Center

    Felty, Amelia Smith

    A case study was conducted of the organized, cooperative efforts of women in six communities in Bolivia. From December 1978 through January 1988, visits were made to women's organizations called "mothers' clubs." Effects of club membership on members, their families, and their communities were examined. A research review showed that: (1) women can…

  4. Book Clubs in Developmental Reading: Building Reading Comprehension, Fostering Reading Enjoyment, and Engaging Students

    ERIC Educational Resources Information Center

    Maldonado, Michele

    2012-01-01

    The use of book clubs in college developmental reading classes is an effective way to encourage reluctant readers to build and strengthen reading skills, foster reading enjoyment, and engage students. In addition, book clubs build a sense of community within the classroom as the students converse and share their interpretations of the reading…

  5. Conflict in a Sixth-Grade Book Club: The Impact of a Rule-Driven Discourse

    ERIC Educational Resources Information Center

    Hill, K. Dara

    2008-01-01

    This study examines unintended consequences during a 6th-grade book club discussion of Bette Bao Lord's (1984) In the Year of the Boar and Jackie Robinson. The participants modeled a book club discussion, otherwise known as the fish bowl, for a newly enrolled student. Unintended consequences occurred within the realm of deviating from the rules of…

  6. Experiential Learning for Preservice Teachers: Digital Book Clubs with Third Graders

    ERIC Educational Resources Information Center

    Stover, Katie; Yearta, Lindsay; Harris, Caroline

    2016-01-01

    This study explored how preservice teachers' knowledge and pedagogy is enhanced through participation of online book clubs with third graders. Qualitative data included pre/post interviews, reflection papers, and blog posts of book club conversations, which were all collected and analyzed. Holistic, in-depth exploration of the recurring themes and…

  7. Reading Lolita in Times of War: Women's Book Clubs and the Politics of Reception

    ERIC Educational Resources Information Center

    Burwell, Catherine

    2007-01-01

    In this article I argue that women's book clubs are significant sites for learning, dialogue and the accumulation of cultural capital, and that research on North American women's book clubs should be expanded to include studies of such groups' consumption of texts by and about women living in the Middle East. Using insights from transnational…

  8. Science Notes: The Clubbers' Guide--School Biology Clubs

    ERIC Educational Resources Information Center

    Howarth, Sue

    2014-01-01

    The STEM team at the University of Worcester support STEM activities in schools in Herefordshire and Worcestershire. Part of this help includes suggesting activities for STEM clubs. As the biologist on the team author, Sue Howarth was asked by teachers for ideas to use in biology clubs. This article was prompted by feedback that these ideas might…

  9. Empowering the Older Job Seeker: Experimental Evaluation of the Older Worker Job Club.

    ERIC Educational Resources Information Center

    Gray, Denis

    Because older job seekers have been shown to exhibit less job search motivation and competence than other groups, a job club program based on learning and self help principles was developed to empower the older job seeker. Of persons (N=48) who requested assistance from a local area agency on aging, half entered the job club program and half were…

  10. The Clio Club: An Extracurricular Model for Elementary Social Studies Enrichment

    ERIC Educational Resources Information Center

    Morris, Ronald Vaughan

    2008-01-01

    This article describes an extracurricular social studies enrichment program called the Clio Club. "Clio" is derived from the Greek muse of history, and the club offers a variety of activities to help students discover and interpret social studies beyond the traditional school hours. They meet after school and on weekends both at their public…

  11. Join a Club! Or a Team--Both Can Make Good Citizens

    ERIC Educational Resources Information Center

    Levine, Peter

    2016-01-01

    Sports participation in high school has positive effects on students' later civic engagement. But that is true of nearly all forms of extracurricular participation in high school--whether a group is explicitly civic (student government or a service club) or far removed from civic life (an academic club or a music group). Indeed, the civic…

  12. Mathematics Teachers' "Learning to Notice" in the Context of a Video Club

    ERIC Educational Resources Information Center

    van Es, Elizabeth A.; Sherin, Miriam Gamoran

    2008-01-01

    This study examines changes in teachers' thinking as they participated in a video club designed to help them learn to notice and interpret students' mathematical thinking. First, we investigate changes in teachers' talk about classroom video segments before and after participation in the video club. Second, we identify three paths along which…

  13. How Different Video Club Designs Support Teachers in "Learning to Notice"

    ERIC Educational Resources Information Center

    van Es, Elizabeth A.; Sherin, Miriam Gamoran

    2006-01-01

    Video is currently a key element of numerous professional development programs, yet relatively little is known about how video fosters changes in teachers' thinking. This study examines how a particular type of video-based professional development, namely video clubs, supports teacher development. Video clubs are professional development…

  14. "With Our Own Wings We Fly": Native American Women Clubs, 1899-1955

    ERIC Educational Resources Information Center

    Tetzloff, Lisa M.

    2007-01-01

    This article traces the history of Native American women clubs from 1899-1955. In its heyday in the early 1900s, the women's club movement attracted about two million participants nationwide. Excluded from higher education at the time, women were moved to create their own opportunities to learn, meeting regularly in small groups to study such…

  15. Private Satisfactions and Public Disorders: "Fight Club," Patriarchy, and the Politics of Masculine Violence.

    ERIC Educational Resources Information Center

    Giroux, Henry A.

    2001-01-01

    Analyzes the narrative structure of the film "Fight Club," addressing its critique of consumerism and its celebration of masculinity. Addresses the representational politics that structure the movie, especially its deeply conventional views of violence, gender relations, and masculinity. Considers the role that "Fight Club" and other cultural…

  16. No Limits--READ! Young Adult Reading Club and Programming Manual.

    ERIC Educational Resources Information Center

    Youngblood, Lisa

    This manual provides strategies for developing young adult collections, outlines a reading club designed specifically for young adults, suggests promotional ideas for the young adult reading club and young adult programming in general, and provides age-appropriate ideas for both formal and passive programming. Specific topics covered in the…

  17. Activist Literacies: An Analysis of the Literacy Practices of a School-Based Human Rights Club

    ERIC Educational Resources Information Center

    Collin, Ross

    2012-01-01

    In this article, I examine the literacy practices of a high school-based human rights club. I investigate how the group engages in certain kinds of textual production to sponsor and arrange advisory sessions (school-wide meetings between teachers and small groups of students). More specifically, I consider how the club adapts school genres to…

  18. Challenges in Offering Inner-City After-School Physical Activity Clubs

    ERIC Educational Resources Information Center

    Maljak, Kimberly; Garn, Alex; McCaughtry, Nate; Kulik, Noel; Martin, Jeffrey; Shen, Bo; Whalen, Laurel; Fahlman, Mariane

    2014-01-01

    Background: Offering physical activity clubs (PACs) for students in urban high schools can provide avenues for increased physical activity (PA); however, little is known about why some clubs are not successful. Purpose: The purpose of this qualitative study was to examine leaders' and students' perspectives on the challenges faced when…

  19. Atrial Septal Aneurysm Presenting as Clubbing without Clinically Apparent Cyanosis.

    PubMed

    Goyal, Laxmi Kant; Banerjee, S; Yadav, R N; Singh, Gajraj; Ganguli, Sujata; Isran, Rohit

    2015-09-01

    Atrial septal aneurysm (ASA) is a localised "saccular" deformity which protrudes to the right or the left atrium or on both sides. It is a rare, but well recognised cardiac abnormality. It is usually an incidental finding or may presents as atrial arrhythmias or arterial embolism. Though it is an acyanotic congenital heart disease but it may result in significant right to left shunt and cyanosis. We describe a patient of ASA with atrial septal defect who presented with clubbing and right to left shunt without clinically apparent cyanosis. PMID:27608873

  20. Preterm birth alters neonatal, functional rich club organization.

    PubMed

    Scheinost, Dustin; Kwon, Soo Hyun; Shen, Xilin; Lacadie, Cheryl; Schneider, Karen C; Dai, Feng; Ment, Laura R; Constable, R Todd

    2016-07-01

    Alterations in neural networks are associated with the cognitive difficulties of the prematurely born. Using functional magnetic resonance imaging, we analyzed functional connectivity for preterm (PT) and term neonates at term equivalent age. Specifically, we constructed whole-brain networks and examined rich club (RC) organization, a common construct among complex systems where important (or "rich") nodes connect preferentially to other important nodes. Both PT and term neonates showed RC organization with PT neonates exhibiting significantly reduced connections between these RC nodes. Additionally, PT neonates showed evidence of weaker functional segregation. Our results suggest that PT birth is associated with fundamental changes of functional organization in the developing brain. PMID:26341628

  1. Prominence and Control: The Weighted Rich-Club Effect

    NASA Astrophysics Data System (ADS)

    Opsahl, Tore; Colizza, Vittoria; Panzarasa, Pietro; Ramasco, José J.

    2008-10-01

    Complex systems are often characterized by large-scale hierarchical organizations. Whether the prominent elements, at the top of the hierarchy, share and control resources or avoid one another lies at the heart of a system’s global organization and functioning. Inspired by network perspectives, we propose a new general framework for studying the tendency of prominent elements to form clubs with exclusive control over the majority of a system’s resources. We explore associations between prominence and control in the fields of transportation, scientific collaboration, and online communication.

  2. The PIP training programme: building of ACP experts capacities in crop protection and food safety to support local companies to comply with EU regulations on pesticides residues.

    PubMed

    Schiffers, B C; Schubert, A; Schiffers, C; Fontaine, S; Gumusboga, N; Werner, B; Webb, M; Lugros, H; Stinglhamber, G

    2006-01-01

    Regulatory requirements, and in particular phytosanitary quality standards change rapidly. As ACP producers/exporters race to become more competitive, to keep their market share and to satisfay their customers' commercial demands (e.g. EUREP-GAP certification), the need for competent staff who are aware of the company's quality objectives and trained to follow instructions is crucial. Mastering sanitary quality is only possible if matched with a programme to build the skills of companies' human resources. The Pesticide Initiative Programme (PIP), mindful of the importance of making operators autonomous and of training them to monitor EU food safety regulations and technology on their own, has successfully developed a training programme while building a quality network of local/ACP service providers. By building the capacities of ACP experts and then securing their services as trainers, PIP also guarantees companies' access to expertise and the sustainability of their efforts to comply with new EU regulations. The training strategy developed by PIP rests on two pilars: instructor training and collective training. Instructor training consists in reinforcing the technical knowledge of local experts (agronomists, hygienists, etc.) by providing them with active teaching methods. Once the ACP experts have gained enough technical knowledge of the key areas of crop protection--mainly pesticides management--and food safety, and have demonstrated their capacity to train the technical staff of local companies, the PIP has carried out a collective training programme in 2004, 2005 and 2006. To date, more than 130 consultants covering about 15 ACP countries have received instructor training, and more than 700 people have participated in collective and in-company training sessions. PMID:17390771

  3. The Juneau County Inventors & Entrepreneurs Club Experience: Catch the Culture! Rural Research Report. Volume 21, Issue 4, Fall 2010

    ERIC Educational Resources Information Center

    Whipple, Terry

    2010-01-01

    Working from the premise that innovation and entrepreneurship will thrive if cultivated in a supportive environment, the Juneau County Economic Development Corporation (JCEDC) introduced a "club concept" as a key component of its strategic plan. The Wisconsin-based development corporation created the Inventors & Entrepreneurs Club (I&E Club) to…

  4. Factors Influencing Blount County, Tennessee Home Demonstration Club Members' Use of Consumer Credit. A Research Summary of a Graduate Study.

    ERIC Educational Resources Information Center

    Neas, Ethel Josephine; And Others

    A study was made of the use of consumer credit by Home Demonstration Club (HDC) members in Blount County, Tennessee, as a basis for planning educational programs. Data were secured by group interviews from 237 Home Demonstration Club members representing 24 clubs. The data were classified according to the members use of consumer credit: those who…

  5. Journals with Borders, Journals without Borders: Under-Representation of Asian Countries in Educational Research Journals

    ERIC Educational Resources Information Center

    Atkinson, Roger

    2013-01-01

    As "Australasian Journal of Educational Technology" (AJET) Production Editor, the author evaluates whether AJET is providing a fair and adequate representation for researchers in Asian countries, with particular reference to AJET's aspiration to be "a front ranked international journal with an Australasian character"…

  6. Rich Club Organization of Macaque Cerebral Cortex and Its Role in Network Communication

    PubMed Central

    Harriger, Logan; van den Heuvel, Martijn P.; Sporns, Olaf

    2012-01-01

    Graph-theoretical analysis of brain connectivity data has revealed significant features of brain network organization across a range of species. Consistently, large-scale anatomical networks exhibit highly nonrandom attributes including an efficient small world modular architecture, with distinct network communities that are interlinked by hub regions. The functional importance of hubs motivates a closer examination of their mutual interconnections, specifically to examine the hypothesis that hub regions are more densely linked than expected based on their degree alone, i.e. forming a central rich club. Extending recent findings of rich club topology in the cat and human brain, this report presents evidence for the existence of rich club organization in the cerebral cortex of a non-human primate, the macaque monkey, based on a connectivity data set representing a collation of numerous tract tracing studies. Rich club regions comprise portions of prefrontal, parietal, temporal and insular cortex and are widely distributed across network communities. An analysis of network motifs reveals that rich club regions tend to form star-like configurations, indicative of their central embedding within sets of nodes. In addition, rich club nodes and edges participate in a large number of short paths across the network, and thus contribute disproportionately to global communication. As rich club regions tend to attract and disperse communication paths, many of the paths follow a characteristic pattern of first increasing and then decreasing node degree. Finally, the existence of non-reciprocal projections imposes a net directional flow of paths into and out of the rich club, with some regions preferentially attracting and others dispersing signals. Overall, the demonstration of rich club organization in a non-human primate contributes to our understanding of the network principles underlying neural connectivity in the mammalian brain, and further supports the hypothesis that

  7. FUTURE OF DERMATOVENEREOLOGICAL JOURNALS1.

    PubMed

    Marinović, Branka

    2016-04-01

    Each year, during the Annual Meeting of the American Academy of Dermatology, there is a meeting of the Council of Dermatology Editors organized by Professor Larry Parish from Philadelphia. It is so nice to meet old friends there and make some new ones, but above all it is a very good platform to discuss the problems journals and their editors are facing today. Some of the topics we discussed during this year's meeting were the increasing number of case reports submitted to all dermatological journals, problems of plagiarism, the rising number of online journals, and the predatory policies quite often connected with them. There was also discussion on print vs online publication versions and on open access journals. It is always useful to discuss common problems, to realize that all journals have similar problems, and to exchange experiences in solving these problems. One of the problems all journals are facing is the increasing number of case reports being submitted, and their high rejection rate due to different reasons. Acta Dermatovenerologica Croatica is overloaded with case reports from many different countries around the world. Most of them are interesting, well prepared cases and could be a good way of exchanging experience between dermatologists. From my personal point of view, case reports are a very useful form of medical communication. For many years they were usually the first articles written by residents under the supervision of their mentors, and I think that all of us should insist on that in the future as well. But the problem is that it has become very difficult to find a journal willing to publish many case reports. Authors are trying to find a journal to publish their case reports in, sometimes sending them to many journals. Unfortunately, the rate of rejection of case reports is rising. And why? There are a few reasons for that, but probably one of the most important is that a high number of published case reports per issue of any journal

  8. Authorship policies of scientific journals

    PubMed Central

    Resnik, David B; Tyle, Ana M; Black, Jennifer R; Kissling, Grace

    2016-01-01

    We analysed the authorship policies of a random sample of 600 journals from the Journal Citation Reports database. 62.5% of the journals we sampled had an authorship policy. Having an authorship policy was positively associated with impact factor. Journals from the biomedical sciences and social sciences/humanities were more likely to have an authorship policy than journals from the physical sciences, engineering or mathematical sciences. Among journals with a policy, the most frequent type of policy was guidance on criteria for authorship (99.7%); followed by guidance on acknowledgments (97.3%); requiring that authors make substantial contributions to the research (94.7%); requiring that authors be accountable for the research as a whole (84.8%); guidance on changes in authorship (77.9%); requiring that authors give final approval to the manuscript (77.6%); requiring that authors draft or critically revise the manuscript (71.7%); providing guidance on corporate authorship (58.9%); prohibiting gift, guest or ghost authorship (31.7%); requiring authors to describe their contributions (5.3%); limiting the number of authors for some types of articles (4.0%) and requiring authors to be accountable for their part in the research (1.1%). None of the policies addressed equal contribution statements. Journals that do not have authorship policies should consider adopting or developing ones. PMID:26714812

  9. Authorship policies of scientific journals.

    PubMed

    Resnik, David B; Tyler, Ana M; Black, Jennifer R; Kissling, Grace

    2016-03-01

    We analysed the authorship policies of a random sample of 600 journals from the Journal Citation Reports database. 62.5% of the journals we sampled had an authorship policy. Having an authorship policy was positively associated with impact factor. Journals from the biomedical sciences and social sciences/humanities were more likely to have an authorship policy than journals from the physical sciences, engineering or mathematical sciences. Among journals with a policy, the most frequent type of policy was guidance on criteria for authorship (99.7%); followed by guidance on acknowledgments (97.3%); requiring that authors make substantial contributions to the research (94.7%); requiring that authors be accountable for the research as a whole (84.8%); guidance on changes in authorship (77.9%); requiring that authors give final approval to the manuscript (77.6%); requiring that authors draft or critically revise the manuscript (71.7%); providing guidance on corporate authorship (58.9%); prohibiting gift, guest or ghost authorship (31.7%); requiring authors to describe their contributions (5.3%); limiting the number of authors for some types of articles (4.0%) and requiring authors to be accountable for their part in the research (1.1%). None of the policies addressed equal contribution statements. Journals that do not have authorship policies should consider adopting or developing ones. PMID:26714812

  10. Baseline Testing of the Club Car Carryall With Asymmetric Ultracapacitors

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2003-01-01

    The NASA John H. Glenn Research Center initiated baseline testing of the Club Car Carryall with asymmetric ultracapacitors as a way to reduce pollution in industrial settings, reduce fossil fuel consumption, and reduce operating costs for transportation systems. The Club Car Carryall provides an inexpensive approach to advance the state of the art in electric vehicle technology in a practical application. The project transfers space technology to terrestrial use via non-traditional partners, and provides power system data valuable for future space applications. The work was done under the Hybrid Power Management (HPM) Program, which includes the Hybrid Electric Transit Bus (HETB). The Carryall is a state of the art, ground up, electric utility vehicle. A unique aspect of the project was the use of a state of the art, long life ultracapacitor energy storage system. Innovative features, such as regenerative braking through ultracapacitor energy storage, are planned. Regenerative braking recovers much of the kinetic energy of the vehicle during deceleration. The Carryall was tested with the standard lead acid battery energy storage system, as well as with an asymmetric ultracapacitor energy storage system. The report concludes that the Carryall provides excellent performance, and that the implementation of asymmetric ultracapacitors in the power system can provide significant performance improvements.

  11. Participation in a Video Club: Influences on Teachers and Teaching

    NASA Astrophysics Data System (ADS)

    Barnhart, Tara

    This dissertation examines the development of critical colleagueship among five secondary science teachers in a semester-long video club. The design of the video club was intended to promote a focus on student thinking and experimentation with elements of ambitious science teaching. Over time, participants sustained a focus on interpreting students' disciplinary thinking using evidence and began to problematize aspects of instruction related to making student thinking visible. Some participants attempted to change instruction to gain greater access to students' disciplinary thinking while others did not. Efforts to experiment with instructional practice appeared related to alignment between participants' learning goals and curricular contexts and the goals of the professional development design. Features such as framing activities, types of artifacts used, and facilitation, interacted differently over time to influence participant learning. Analysis revealed various tensions among the elements of the learning ecology that influenced participation. Findings from this study contribute to what is known about the importance of skilled facilitation as part of a learning ecology (Cobb, Confrey, diSessa, Lehrer, & Schauble, 2003) and has implications for the design of site-based professional development with secondary teachers.

  12. Tracking club sport participation from childhood to early adulthood.

    PubMed

    Richards, Rosalina; Williams, Sheila; Poulton, Richie; Reeder, Anthony I

    2007-12-01

    This study examined the strength of tracking sport participation from childhood to early adulthood among the Dunedin Multidisciplinary Health and Development Study cohort. Participation in sport, dance, or gymnastics as part of a club or group (outside of school) was assessed at ages 7, 9, 15, 18, and 21 years. In addition to the traditionally used correlation coefficients, summary statistics (intraclass correlations; ICC) from random effect models and stability coefficients from generalized estimating equations (GEE) were calculated using all the longitudinal data and controlling for the influence of covariates on tracking strength. Correlation coefficients revealed statistically significant tracking of club sport participation (7-21 years) at low levels (r = .07-0.28). The ICC summary statistic (0.23) was consistent with this, while the GEE suggested moderate tracking (0.59). The results of this study suggest that encouraging sport participation during childhood and adolescence may result in a modest increase in the likelihood of participation later in life. However, the substantial movement into and out of sport participation observed here and in other studies cautions against relying solely on sport promotion among youth as a strategy to promote lifelong participation. PMID:18274213

  13. Journaling: creating space for "I".

    PubMed

    Charles, Jennell P

    2010-01-01

    As nurses engaged in a caring profession, it is critical that we learn not only to care for others but also to care for ourselves. To care effectively for ourselves, we must create the space and time in which to do this. Journaling is one tool that scholars offer as a way to create this space. Although there is no clear consensus about the best techniques for journaling, there is evidence that journaling, as a reflective, meditative activity, can promote creativity, self-awareness, and personal development. PMID:21140872

  14. Increasing Opportunities for Older Youth in After-School Programs. A Report on the Experiences of Boys & Girls Clubs in Boston and New York City.

    ERIC Educational Resources Information Center

    Herrera, Carla; Arbreton, Amy J. A.

    Boys & Girls Clubs in New York City and Boston participated in a 3-year initiative to provide and enhance services to underserved teens. Researchers collected data via surveys of club members and staff; cost surveys of club administrators; interviews, focus groups, and observations at each club; and attendance information. Results indicated that…

  15. Journalism Program to Fill Gap

    ERIC Educational Resources Information Center

    Goodman, Henry

    1970-01-01

    The preparation of interested and well-trained individuals for service in editorial, advertising, and management positions on rural and small town newspapers is the intent of Sampson Technical Institute's 2-year pilot journalism program. (JO)

  16. EDITORIAL: Changes to the journal Changes to the journal

    NASA Astrophysics Data System (ADS)

    Zheludev, Nikolay I.

    2010-01-01

    It is a privilege to be Editor-in-Chief of Journal of Optics at this exciting time when the use of light spearheads the development of new technologies in telecommunications, green energy, manufacturing, medicine and defence, just to mention a few. These technological advances, seen by many as the next photonic technological revolution, are underpinned by fundamental and applied research in the following key directions: Nanophotonics and plasmonics Metamaterials and structured photonic materials Nonlinear and ultrafast optics Photonics at the life science interface Information and communication optics Integrated optics systems and devices Material processing with light Propagation, diffraction and scattering This is where Journal of Optics focuses its attention. This editorial marks the first issue of the journal published under the abbreviated name (shortened from Journal of Optics A: Pure and Applied Optics). The name change is just one of a series of changes introduced in the last year, along with the 8 subject sections listed above and the appointment of Section Editors. With the name change, we will also update the look of the journal by introducing colour cover images which will feature some of the most exciting research in the journal. We have retained many of the journal's original selling points: we are found in thousands of libraries around the world, and will continue our policy of free web access to all papers for 30 days after publication, ensuring broad and unrestricted dissemination of your research results. We will also continue our strong and well respected special issue and topical review programmes and we are always grateful to receive new suggestions for special issues or review articles. Along with the Editorial Board, I would like to thank the authors, referees and readers who have contributed to the success of Journal of Optics. The increasing quality and visibility of the journal, as demonstrated by the dramatic increase in its impact factor

  17. Further Enhancement of the Astronomy Club at the University of Arizona

    NASA Astrophysics Data System (ADS)

    Biddle, Lauren I.; Towner, A. P.; McGraw, A. M.; Walker-LaFollette, A.

    2013-06-01

    The University of Arizona Astronomy Club has progressed into what is now a thriving organization. The Astronomy Club has been successful in involving undergraduates in research and community outreach as well as building bonds between students. We have big plans for further development of the organization, while maintaining an exciting, informative, and enjoyable atmosphere for its members. One focus for the future of Astronomy Club is to develop a stronger professional presence within the astronomy department and community. In order to accomplish this goal, we will encourage member attendance at meetings such as the AAS and local talks given at Steward Observatory. Students will benefit from this learning more about subjects other than their own research. Students also benefit from social connections, and, to that end, we plan to continue and expand club social and outreach activities. Another advancement is the club web page, which provides both members, non-members, and the general public with useful resources such as programming guides, “how-to’s,” and links to online resources. A survey was distributed to the members of Astronomy Club to get feedback on how the organization can make their experience at the UofA both educational and fun. We have review the responses and make decisions based on what the members want. in activities is important to increase membership, maintain attendance, and sustain the club as a whole. The most important goal for the organization is that it will continue to evolve through years, long after the current members are graduated.

  18. [French medical journals since 1800].

    PubMed

    Tesnière, Valérie; Cantau, Alina

    2014-01-01

    French medical journals take the lead among the 1 385 titles of the statistical survey (15.4%). Efficient tool in communication, with an important publishing market, linked to the rise of medicine in the 19(th) century, prosperity of medical journals do not only mean rise of specialties. Monthly periodicals dominate quickly the publishing market which is also characterized by complex links between generalist and highly specialized medicine, public health and professional training. PMID:25311892

  19. An Overview and Analysis of Journal Operations, Journal Publication Patterns, and Journal Impact in School Psychology and Related Fields

    ERIC Educational Resources Information Center

    Floyd, Randy G.; Cooley, Kathryn M.; Arnett, James E.; Fagan, Thomas K.; Mercer, Sterett H.; Hingle, Christine

    2011-01-01

    This article describes the results of three studies designed to understand better the journal operations, publishing practices, and impact of school psychology journals in recent years. The first study presents the results of a survey focusing on journal operations and peer-review practices that was completed by 61 journal editors of school…

  20. Peer Feedback Enhances a "Journal Club" for Undergraduate Science Students That Develops Oral Communication and Critical Evaluation Skills

    ERIC Educational Resources Information Center

    Colthorpe, Kay; Chen, Xuebin; Zimbardi, Kirsten

    2014-01-01

    Effective science communication is one of the key skills undergraduates must achieve and is one of the threshold learning outcomes for Science (TLO 4.1). In addition, presenting published research to their peers allows students to critically evaluate scientific research (TLO 3.1) and develop a deeper appreciation for the link between experimental…