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Sample records for acquired preparedness model

  1. Longitudinal validation of the acquired preparedness model of drinking risk.

    PubMed

    Settles, Regan Fried; Cyders, Melissa; Smith, Gregory T

    2010-06-01

    This paper reports on the first longitudinal test of the Acquired Preparedness (AP) model of alcoholism risk, which holds that individual differences in key personality traits influence drinking behavior by influencing alcohol-related learning (Smith and Anderson, 2001). We studied 418 individuals making the transition to the independence of college across 3 longitudinal waves. Each of 2 longitudinal models predicting typical drinking quantity provided support for the AP process. In the first, drinking quantity at the end of the first year of college was predicted by positive urgency (the tendency to act rashly when experiencing extremely positive affect) at the start of college, and that predictive relationship appeared to have been mediated by expectancies that alcohol provides positive, arousing effects. In the second, drinking quantity was predicted by negative urgency (the tendency to act rashly when experiencing extremely negative affect) at the start of college, and that relationship appeared to have been mediated by the motive to drink alcohol to cope with subjective distress. PMID:20565146

  2. Testing the Acquired Preparedness Model: Predicting College Student Gambling Frequency and Symptomatology

    PubMed Central

    Ginley, Meredith K.; Whelan, James P.; Relyea, George, E.; Meyers, Andrew W.; Pearlson, Godfrey D.

    2014-01-01

    The acquired preparedness model posits that impulsivity influences the development of outcome expectancies that then influence the engagement in a specific risk taking behavior. The purpose of this study was to test the acquired preparedness model for gambling behavior of college students using a multidimensional approach to impulsivity. Employing a structural equation approach, it was predicted that a full mediational model that includes multiple dimensions of impulsivity and multiple outcome expectancies would predict gambling frequency and gambling symptomatology. Support was found for the acquired preparedness model in understanding why some college students gamble more frequently or problematically. Specifically, better model fit was found for the full mediational model that included outcome expectancies to predict both frequency and gambling symptomatology than the model that included the direct relation between impulsivity and gambling. PMID:24563083

  3. A Comprehensive Longitudinal Test of the Acquired Preparedness Model for Alcohol Use and Related Problems*

    PubMed Central

    Corbin, William R.; Iwamoto, Derek K.; Fromme, Kim

    2011-01-01

    Objective: According to the acquired preparedness model (APM), personality traits related to disinhibition (i.e., impulsivity and sensation seeking) may influence the learning process, contributing to individual differences in cognitions (e.g., expectations about outcomes) that may contribute to engagement in and consequences of risk behaviors, including alcohol use. Although there is strong support for the APM, longitudinal studies have involved short-term follow-ups, and the relevance of the APM for alcohol-related consequences has not been clearly established. Method: Participants were 2,245 (59.9% female) incoming freshmen who completed the first of eight web-based surveys during the summer before college matriculation. Structural equation modeling was used to test a comprehensive longitudinal APM for both alcohol use and related consequences. Multigroup models were used to examine measurement and structural invariance by gender. Results: Positive (but not negative) alcohol expectancies during freshman year of college partially mediated the relation between senior year of high school disinhibition and both alcohol use and related problems during the fourth year of college, and multigroup models suggested that the relationships proposed in the APM operated similarly for women and men. Conclusions: This study demonstrates the temporal relations proposed in the APM across a longer period (4 years) than in previous studies among a large sample of ethnically diverse students. Further, the results are the first to validate the APM with respect to drinking consequences while controlling for levels of alcohol use. The results lend support for brief interventions targeting positive alcohol expectancies, particularly for individuals high in trait disinhibition. PMID:21683042

  4. Disordered models of acquired dyslexia

    NASA Astrophysics Data System (ADS)

    Virasoro, M. A.

    We show that certain specific correlations in the probability of errors observed in dyslexic patients that are normally explained by introducing additional complexity in the model for the reading process are typical of any Neural Network system that has learned to deal with a quasiregular environment. On the other hand we show that in Neural Networks the more regular behavior does not become naturally the default behavior.

  5. Cross-cultural comparisons between the earthquake preparedness models of Taiwan and New Zealand.

    PubMed

    Jang, Li-Ju; Wang, Jieh-Jiuh; Paton, Douglas; Tsai, Ning-Yu

    2016-04-01

    Taiwan and New Zealand are both located in the Pacific Rim where 81 per cent of the world's largest earthquakes occur. Effective programmes for increasing people's preparedness for these hazards are essential. This paper tests the applicability of the community engagement theory of hazard preparedness in two distinct cultural contexts. Structural equation modelling analysis provides support for this theory. The paper suggests that the close fit between theory and data that is achieved by excluding trust supports the theoretical prediction that familiarity with a hazard negates the need to trust external sources. The results demonstrate that the hazard preparedness theory is applicable to communities that have previously experienced earthquakes and are therefore familiar with the associated hazards and the need for earthquake preparedness. The paper also argues that cross-cultural comparisons provide opportunities for collaborative research and learning as well as access to a wider range of potential earthquake risk management strategies. PMID:26282331

  6. The Development of a Multi-Level Model for Crisis Preparedness and Intervention in the Greek Educational System

    ERIC Educational Resources Information Center

    Hatzichristiou, Chryse; Issari, Philia; Lykitsakou, Konstantina; Lampropoulou, Aikaterini; Dimitropoulou, Panayiota

    2011-01-01

    This article proposes a multi-level model for crisis preparedness and intervention in the Greek educational system. It presents: a) a brief overview of leading models of school crisis preparedness and intervention as well as cultural considerations for contextually relevant crisis response; b) a description of existing crisis intervention…

  7. The meta-leadership summit for preparedness initiative: an innovative model to advance public health preparedness and response.

    PubMed

    Sobelson, Robyn K; Young, Andrea C; Marcus, Leonard J; Dorn, Barry C; Neslund, Verla S; McNulty, Eric J

    2013-12-01

    This article reports on the design, evaluation framework, and results from the Meta-Leadership Summit for Preparedness Initiative. The Meta-Leadership Summit for Preparedness was a 5-year initiative based on the premise that national preparedness and emergency response is not solely the responsibility of government. From 2006 to 2011, 36 Meta-Leadership Summits were delivered in communities across the country. Summits were customized, 10-hour leadership development, networking, and community action planning events. They included participation from targeted federal, state, local, nonprofit/philanthropic, and private sector leaders who are directly involved in decision making during a major community or state-wide emergency. A total of 4,971 government, nonprofit, and business leaders attended Meta-Leadership Summits; distribution of attendees by sector was balanced. Ninety-three percent of respondents reported the summit was a valuable use of time, 91% reported the overall quality as "good" or "outstanding," and 91% would recommend the summit to their colleagues. In addition, approximately 6 months after attending a summit, 80% of respondents reported that they had used meta-leadership concepts or principles. Of these, 93% reported that using meta-leadership concepts or principles had made a positive difference for them and their organizations. The Meta-Leadership Summit for Preparedness Initiative was a value-added opportunity for communities, providing the venue for learning the concepts and practice of meta-leadership, multisector collaboration, and resource sharing with the intent of substantively improving preparedness, response, and recovery efforts. PMID:24251597

  8. Modeling pandemic preparedness scenarios: health economic implications of enhanced pandemic vaccine supply.

    PubMed

    Medema, Jeroen K; Zoellner, York F; Ryan, James; Palache, Abraham M

    2004-07-01

    Influenza pandemic planning is a complex, multifactorial process, which involves public health authorities, regulatory authorities, academia and industry. It is further complicated by the unpredictability of the time of emergence and severity of the next pandemic and the effectiveness of influenza epidemic interventions. The complexity and uncertainties surrounding pandemic preparedness have so far kept the various stakeholders from joining forces and tackling the problem from its roots. We developed a mathematical model, which shows the tangible consequences of conceptual plans by linking possible pandemic scenarios to health economic outcomes of possible intervention strategies. This model helps to structure the discussion on pandemic preparedness and facilitates the translation of pandemic planning concepts to concrete plans. The case study for which the model has been used shows the current level of global pandemic preparedness in an assumed pandemic scenario, the health economic implications of enhanced pandemic vaccine supply and the importance of cell culture-based influenza vaccine manufacturing technologies as a tool for pandemic control. PMID:15163482

  9. Computational fluid dynamics modeling for emergency preparedness and response

    SciTech Connect

    Lee, R.L.; Albritton, J.R.; Ermak, D.L.; Kim, J.

    1995-02-01

    Computational fluid dynamics (CFD) has (CFD) has played an increasing in the improvement of atmospheric dispersion modeling. This is because many dispersion models are now driven by meteorological fields generated from CFD models or, in numerical weather prediction`s terminology, prognostic models. Whereas most dispersion models typically involve one or a few scalar, uncoupled equations, the prognostic equations are a set of highly-couple equations whose solution requires a significant level of computational power. Recent advances in computer hardware and software have enabled modestly-priced, high performance, workstations to exhibit the equivalent computation power of some mainframes. Thus desktop-class machines that were limited to performing dispersion calculations driven by diagnostic wind fields may now be used to calculate complex flows using prognostic CFD models. The Release and Advisory Capability (ARAC) program at Lawrence Livermore National Laboratory (LLNL) has, for the past several years, taken advantage of the improvements in hardware technology to develop a national emergency response capability based on executing diagnostic models on workstations. Diagnostic models that provide wind fields are, in general, simple to implement, robust and require minimal time for execution. Because these models typically contain little physics beyond mass-conservation, their performance is extremely sensitive to the quantity and quality of input meteorological data and, in spite of their utility, can be applied with confidence to only modestly complex flows. We are now embarking on a development program to incorporate prognostic models to generate, in real-time, the meteorological fields for the dispersion models. In contrast to diagnostic models, prognostic models are physically-based and are capable of incorporating many physical processes to treat highly complex flow scenarios.

  10. Computational fluid dynamics modeling for emergency preparedness & response

    SciTech Connect

    Lee, R.L.; Albritton, J.R.; Ermak, D.L.; Kim, J.

    1995-07-01

    Computational fluid dynamics (CFD) has played an increasing role in the improvement of atmospheric dispersion modeling. This is because many dispersion models are now driven by meteorological fields generated from CFD models or, in numerical weather prediction`s terminology, prognostic models. Whereas most dispersion models typically involve one or a few scalar, uncoupled equations, the prognostic equations are a set of highly-coupled, nonlinear equations whose solution requires a significant level of computational power. Until recently, such computer power could be found only in CRAY-class supercomputers. Recent advances in computer hardware and software have enabled modestly-priced, high performance, workstations to exhibit the equivalent computation power of some mainframes. Thus desktop-class machines that were limited to performing dispersion calculations driven by diagnostic wind fields may now be used to calculate complex flows using prognostic CFD models. The Atmospheric Release and Advisory Capability (ARAC) program at Lawrence Livermore National Laboratory (LLNL) has, for the past several years, taken advantage of the improvements in hardware technology to develop a national emergency response capability based on executing diagnostic models on workstations. Diagnostic models that provide wind fields are, in general, simple to implement, robust and require minimal time for execution. Such models have been the cornerstones of the ARAC operational system for the past ten years. Kamada (1992) provides a review of diagnostic models and their applications to dispersion problems. However, because these models typically contain little physics beyond mass-conservation, their performance is extremely sensitive to the quantity and quality of input meteorological data and, in spite of their utility, can be applied with confidence to only modestly complex flows.

  11. Disaster Preparedness.

    ERIC Educational Resources Information Center

    Brooks, Constance

    Most librarians know the importance of disaster preparedness. Many disasters could have been prevented altogether or have had reduced impact if institutions had been better prepared. This resource guide suggests how disaster preparedness can be achieved at cultural institutions. Twenty-three basic resource articles are presented to introduce…

  12. Emergency preparedness

    SciTech Connect

    Yanev, P.I.; Hom, S.; Kircher, C.A.; Bailey, N.D.

    1985-01-01

    These lecture notes include the following subject areas: (1) earthquake mitigation planning - general approach and in-house program; (2) seismic protection of equipment and non-structural systems; and (3) disaster preparedness and self help program. (ACR)

  13. A Model for Evaluating and Acquiring Educational Software in Psychology.

    ERIC Educational Resources Information Center

    Brown, Stephen W.; And Others

    This paper describes a model for evaluating and acquiring instructionally effective and cost effective educational computer software in university psychology departments. Four stages in evaluating the software are developed: (1) establishing departmental goals and objectives for educational use of computers; (2) inventorying and evaluating…

  14. Preparedness 101: Zombie Pandemic

    MedlinePlus

    ... Preparedness and Response Activities Public Health Preparedness Capabilities Cities Readiness Initiative Funding and Technical Assistance Healthcare Preparedness Subscribe to Receive Updates Planning Resources Communities Community Planning Framework for Healthcare Preparedness ...

  15. Epicutaneous model of community-acquired Staphylococcus aureus skin infections.

    PubMed

    Prabhakara, Ranjani; Foreman, Oded; De Pascalis, Roberto; Lee, Gloria M; Plaut, Roger D; Kim, Stanley Y; Stibitz, Scott; Elkins, Karen L; Merkel, Tod J

    2013-04-01

    Staphylococcus aureus is one of the most common etiological agents of community-acquired skin and soft tissue infection (SSTI). Although the majority of S. aureus community-acquired SSTIs are uncomplicated and self-clearing in nature, some percentage of these cases progress into life-threatening invasive infections. Current animal models of S. aureus SSTI suffer from two drawbacks: these models are a better representation of hospital-acquired SSTI than community-acquired SSTI, and they involve methods that are difficult to replicate. For these reasons, we sought to develop a murine model of community-acquired methicillin-resistant S. aureus SSTI (CA-MRSA SSTI) that can be consistently reproduced with a high degree of precision. We utilized this model to begin to characterize the host immune response to this type of infection. We infected mice via epicutaneous challenge of the skin on the outer ear pinna using Morrow-Brown allergy test needles coated in S. aureus USA300. When mice were challenged in this model, they developed small, purulent, self-clearing lesions with predictable areas of inflammation that mimicked a human infection. CFU in the ear pinna peaked at day 7 before dropping by day 14. The T(h)1 and T(h)17 cytokines gamma interferon (IFN-γ), interleukin-12 (IL-12) p70, tumor necrosis factor alpha (TNF-α), IL-17A, IL-6, and IL-21 were all significantly increased in the draining lymph node of infected mice, and there was neutrophil recruitment to the infection site. In vivo neutrophil depletion demonstrated that neutrophils play a protective role in preventing bacterial dissemination and fatal invasive infection. PMID:23381997

  16. Disaster Preparedness

    PubMed Central

    Achora, Susan; Kamanyire, Joy K.

    2016-01-01

    With the increasing global frequency of disasters, the call for disaster preparedness training needs to be reinforced. Nurses form the largest group of the healthcare workforce and are often on the frontline in disaster management. Therefore, nurses should be adequately equipped with the knowledge and skills to respond to disasters, starting from their pre-service training to their in-service professional training. However, the inclusion of disaster preparedness education in undergraduate nursing curricula is minimal in most countries. The purpose of this article is to highlight the current state of nursing education and training in disaster management, both generally and in Oman. The significance of disaster preparedness training and recommendations for its inclusion in nursing practice and education are also discussed. PMID:26909207

  17. Hurricane Preparedness

    MedlinePlus

    ... Edit Zip Code Edit Zip Code Shop the Red Cross Store Home Get Help Types of Emergencies Hurricane Preparedness Download the FREE Emergency App Find our Emergency App in the Apple Store or Google Play Aplicación de Emergencias - ahora ...

  18. Hurricane Preparedness

    MedlinePlus

    ... one app. Text GETEMERGENCY to 90999 or search "Red Cross Emergency" in the Apple App Store or Google Play Store . Prepare for Hurricanes Are You Ready for a Hurricane? Ruben Brown of the American Red Cross helps a family assemble a preparedness kit ...

  19. Acquiring neural signals for developing a perception and cognition model

    NASA Astrophysics Data System (ADS)

    Li, Wei; Li, Yunyi; Chen, Genshe; Shen, Dan; Blasch, Erik; Pham, Khanh; Lynch, Robert

    2012-06-01

    The understanding of how humans process information, determine salience, and combine seemingly unrelated information is essential to automated processing of large amounts of information that is partially relevant, or of unknown relevance. Recent neurological science research in human perception, and in information science regarding contextbased modeling, provides us with a theoretical basis for using a bottom-up approach for automating the management of large amounts of information in ways directly useful for human operators. However, integration of human intelligence into a game theoretic framework for dynamic and adaptive decision support needs a perception and cognition model. For the purpose of cognitive modeling, we present a brain-computer-interface (BCI) based humanoid robot system to acquire brainwaves during human mental activities of imagining a humanoid robot-walking behavior. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model. The BCI system consists of a data acquisition unit with an electroencephalograph (EEG), a humanoid robot, and a charge couple CCD camera. An EEG electrode cup acquires brainwaves from the skin surface on scalp. The humanoid robot has 20 degrees of freedom (DOFs); 12 DOFs located on hips, knees, and ankles for humanoid robot walking, 6 DOFs on shoulders and arms for arms motion, and 2 DOFs for head yaw and pitch motion. The CCD camera takes video clips of the human subject's hand postures to identify mental activities that are correlated to the robot-walking behaviors. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model.

  20. Proposing and Testing a Model to Explain Traits of Algebra Preparedness

    ERIC Educational Resources Information Center

    Venenciano, Linda; Heck, Ronald

    2016-01-01

    Early experiences with theoretical thinking and generalization in measurement are hypothesized to develop constructs we name here as logical reasoning and preparedness for algebra. Based on work of V. V. Davydov (1975), the Measure Up (MU) elementary grades experimental mathematics curriculum uses quantities of area, length, volume, and mass to…

  1. Model for preparedness of a public institution for a terrorist attack.

    PubMed

    Lifshitz, Izak; Adler, Jakov; Katz, Joseph

    2008-01-01

    Public institutions such as governmental facilities, hospitals, universities, and amusement parks may be targeted by terrorists using weapons of mass destruction due to their potential to cause large numbers of casualties. Consequentially, these institutions should be prepared to manage such an event by the development and implementation of specific preparedness guidelines for any conventional or unconventional terrorist attacks. In order to test the preparedness of such an institution for a chemical event, a large-scale drill focusing on the first medical team to respond was conducted. Some important lessons regarding the way the medical team operates and communicates were learned from this drill. Periodic drills should be performed in order to assess the practicality and applicability of these guidelines. PMID:19189617

  2. Using the Precaution Adoption Process model to describe a disaster preparedness intervention among low-income Latinos.

    PubMed

    Glik, Deborah C; Eisenman, David P; Zhou, Qiong; Tseng, Chi-Hong; Asch, Steven M

    2014-04-01

    Only 40-50% of households in the United States are currently disaster prepared. In this intervention study, respondent-driven sampling was used to select a sample (n = 187) of low income, Latino residents of Los Angeles County, randomly assigned into two treatment conditions: (i) household preparedness education received through 'promotora' (community health worker) led small group meetings, and (ii) household preparedness education received through print media. Weinstein's Precaution Adoption Process, a stage model appropriate for risk communication guided the intervention. Outcomes are conceptualized as stages of decision making linked to having disaster supplies and creating a family communication plan. Quantitative results showed a significant shift over time from awareness to action and maintenance stages for disaster communication plans and supplies in both study arms; however, the shift in stage for a communication plan for those in the 'platica' study arm was (P < 0.0001) than for those in the media arm. For changes in stage linked to disaster supplies, people in both media and 'platica' study arms improved at the same rate. Simple media-based communications may be sufficient to encourage disadvantaged households to obtain disaster supplies; however, adoption of the more complex disaster family communication requires interpersonal education. PMID:24399266

  3. Development of a resource modelling tool to support decision makers in pandemic influenza preparedness: The AsiaFluCap Simulator

    PubMed Central

    2012-01-01

    Background Health care planning for pandemic influenza is a challenging task which requires predictive models by which the impact of different response strategies can be evaluated. However, current preparedness plans and simulations exercises, as well as freely available simulation models previously made for policy makers, do not explicitly address the availability of health care resources or determine the impact of shortages on public health. Nevertheless, the feasibility of health systems to implement response measures or interventions described in plans and trained in exercises depends on the available resource capacity. As part of the AsiaFluCap project, we developed a comprehensive and flexible resource modelling tool to support public health officials in understanding and preparing for surges in resource demand during future pandemics. Results The AsiaFluCap Simulator is a combination of a resource model containing 28 health care resources and an epidemiological model. The tool was built in MS Excel© and contains a user-friendly interface which allows users to select mild or severe pandemic scenarios, change resource parameters and run simulations for one or multiple regions. Besides epidemiological estimations, the simulator provides indications on resource gaps or surpluses, and the impact of shortages on public health for each selected region. It allows for a comparative analysis of the effects of resource availability and consequences of different strategies of resource use, which can provide guidance on resource prioritising and/or mobilisation. Simulation results are displayed in various tables and graphs, and can also be easily exported to GIS software to create maps for geographical analysis of the distribution of resources. Conclusions The AsiaFluCap Simulator is freely available software (http://www.cdprg.org) which can be used by policy makers, policy advisors, donors and other stakeholders involved in preparedness for providing evidence based and

  4. Modeling Technology Preparedness as an Antecedent of Mathematic Pre-Service Teachers' Self Efficacy, Perceived Usefulness and Intention toward Use of Information Technology in Nigeria

    ERIC Educational Resources Information Center

    Shittu, Ahmed Tajudeen; Gambari, Amosa Isiaka; Gimba, W. Rahmatu; Ahmed, Hassan

    2016-01-01

    This study test a specified model of information technology (IT) preparedness as antecedent of pre-service teachers' self efficacy, perceived usefulness, and intention toward IT use for teaching in Nigeria. Survey method was employed for prosecuting the study. The participants of the study comprise of 200 pre-service teachers studying Mathematics…

  5. Legal Preparedness

    PubMed Central

    Courtney, Brooke; Hodge, James G.; Toner, Eric S.; Roxland, Beth E.; Penn, Matthew S.; Devereaux, Asha V.; Dichter, Jeffrey R.; Kissoon, Niranjan; Christian, Michael D.; Powell, Tia

    2015-01-01

    contribute to protecting hospitals and practitioners who act in good faith from liability. Finally, to address anticipated staffing shortages during severe and prolonged disasters and pandemics, governments should develop approaches to formally expand the availability of qualified health-care workers, such as through using official foreign medical teams. CONCLUSIONS As a fundamental element of health-care and public health emergency planning and preparedness, the law underlies critical aspects of disaster and pandemic responses. Effective responses require comprehensive advance planning efforts that include assessments of complex legal issues and authorities. Recent disasters have shown that although law is a critical response tool, it can also be used to hold health-care stakeholders who fail to appropriately plan for or respond to disasters and pandemics accountable for resulting patient or staff harm. Claims of liability from harms allegedly suffered during disasters and pandemics cannot be avoided altogether. However, appropriate planning and legal protections can help facilitate sound, consistent decision-making and support response participation among health-care entities and practitioners. PMID:25144203

  6. Financing hospital disaster preparedness.

    PubMed

    De Lorenzo, Robert A

    2007-01-01

    Disaster preparedness and response have gained increased attention in the United States as a result of terrorism and disaster threats. However, funding of hospital preparedness, especially surge capacity, has lagged behind other preparedness priorities. Only a small portion of the money allocated for national preparedness is directed toward health care, and hospitals receive very little of that. Under current policy, virtually the entire funding stream for hospital preparedness comes from general tax revenues. Medical payers (e.g., Medicare, Medicaid, and private insurance) directly fund little, if any, of the current bill. Funding options to improve preparedness include increasing the current federal grants allocated to hospitals, using payer fees or a tax to subsidize preparedness, and financing other forms of expansion capability, such as mobile hospitals. Alternatively, the status quo of marginal preparedness can be maintained. In any event, achieving higher levels of preparedness likely will take the combined commitment of the hospital industry, public and private payers, and federal, state, and local governments. Ultimately, the costs of preparedness will be borne by the public in the form of taxes, higher healthcare costs, or through the acceptance of greater risk. PMID:18087914

  7. Acquiring, Representing, and Evaluating a Competence Model of Diagnostic Strategy.

    ERIC Educational Resources Information Center

    Clancey, William J.

    This paper describes NEOMYCIN, a computer program that models one physician's diagnostic reasoning within a limited area of medicine. NEOMYCIN's knowledge base and reasoning procedure constitute a model of how human knowledge is organized and how it is used in diagnosis. The hypothesis is tested that such a procedure can be used to simulate both…

  8. The transitional medical model: an innovative methodology for a community's disease outbreak and pandemic preparedness and response plan.

    PubMed

    Rega, Paul; Bork, Christopher; Bisesi, Michael; Gold, Jeffrey; Burkholder-Allen, Kelly

    2010-01-01

    Infectious disease outbreaks, epidemics, and subsequent pandemics are not typical disasters in the sense that they often lack clearly delineated phases. As in any event that is biological in nature, its onset may be gradual with signs and symptoms that are so subtle that they go unrecognized, thus missing opportunities to invoke an early response and implement containment strategies. An infectious disease outbreak-whether caused by a novel virus, a particularly virulent influenza strain, or newly emerging or resistant bacteria with the capability of human-to-human transmission--can quickly degrade a community's healthcare infrastructure in advance of coordinated mitigation, preparation, and response activities. The Transitional Medical Model (TMM) was developed to aid communities with these crucial phases of disaster response as well as to assist with the initial steps within the recovery phase. The TMM is a methodology that provides a crosswalk between the routine operations and activities of a community's public health infrastructure with action steps associated with the mitigation, preparedness, response, and recovery phases of an infectious disease outbreak. PMID:20496640

  9. "Analyze, Acquire, Apply, and Write" as a New Learning Model in Science

    ERIC Educational Resources Information Center

    Choe, Jeong V.

    2015-01-01

    I have developed a new teaching and learning model called AAAW, which stand for Analyze, Acquire, Apply and Write. This model grows from action research and unique experience in teaching a biochemistry course to high school students who are talented in math and science. In this model, students first "Analyze" lab data to generate…

  10. Vested Interest theory and disaster preparedness.

    PubMed

    Miller, Claude H; Adame, Bradley J; Moore, Scott D

    2013-01-01

    Three studies were designed to extend a combination of vested interest theory (VI) and the extended parallel process model of fear appeals (EPPM) to provide formative research for creating more effective disaster preparedness social action campaigns. The aim was to develop an effective VI scale for assessing individual awareness and 'vestedness' relevant to disaster preparedness. Typical preparedness behaviours are discussed with emphasis on earthquakes and tornados in particular. Brief overviews of VI and the EPPM are offered, and findings are presented from three studies (one dealing with earthquakes, and two with tornados) conducted to determine the factor structure of the key VI components involved, and to develop and test subscales derived from the two theories. The paper finishes with a discussion of future research needs and suggestions on how the new subscales may be applied in the design and execution of more effective disaster preparedness campaigns. PMID:23050780

  11. Using the Precaution Adoption Process Model to Describe a Disaster Preparedness Intervention among Low-Income Latinos

    ERIC Educational Resources Information Center

    Glik, Deborah C.; Eisenman, David P.; Zhou, Qiong; Tseng, Chi-Hong; Asch, Steven M.

    2014-01-01

    Only 40-50% of households in the United States are currently disaster prepared. In this intervention study, respondent-driven sampling was used to select a sample (n = 187) of low income, Latino residents of Los Angeles County, randomly assigned into two treatment conditions: (i) household preparedness education received through…

  12. The Mobile Library and Staff Preparedness: Exploring Staff Competencies Using the Unified Theory of Acceptance and Use of Technology Model

    ERIC Educational Resources Information Center

    Saravani, Sarah-Jane; Haddow, Gaby

    2011-01-01

    This paper presents preliminary findings of a study investigating the current state of preparedness of staff at institutes of technology and TAFE libraries across Australia and New Zealand in relation to delivering services through mobile technologies. In particular, the skills, knowledge, and competencies of staff in relation to mobile…

  13. An Integrated Model of School Crisis Preparedness and Intervention. A Shared Foundation to Facilitate International Crisis Intervention

    ERIC Educational Resources Information Center

    Jimerson, Shane R.; Brock, Stephen E.; Pletcher, Sarah W.

    2005-01-01

    In an effort to promote the social and cognitive competence of youth, school psychologists must be prepared to address a multitude of contextual factors and life events that impact children's performance and adjustment in school and subsequent developmental trajectories. The domain of crisis preparedness and intervention has received increased…

  14. Toward Establishing the Validity of the Transformative Optimism Construct Measurement for Tsunami Preparedness: A Structural Equation Model for Visitors of the Pacific Northwest Coast

    ERIC Educational Resources Information Center

    Rios-Uribe, Carlos Andres

    2009-01-01

    Measurements of social constructs that evaluate natural hazard preparedness are important to decrease natural hazard vulnerability. Preparedness reduces natural hazard impacts and human vulnerability. Investment in education and education research contribute to human sustainable development and natural hazard preparedness. Faced with other needs,…

  15. 17. Introduction to preparedness.

    PubMed

    2014-05-01

    Preparedness is the aggregate of all measures and policies adopted before an event occurs that promotes mitigation of the damage caused by an event and minimises the dysfunction that could result from the damage. More specifically, it includes all planning and resources that are devoted to preventing deaths and morbidity and, thus, to the alleviation of human (individual and collective) suffering during and after the event has taken place. It consists of measures that individuals, a family, a community, locale, country, region, institution, and states maintain, at a particular time, to combat the potential deleterious effects of hazards. Preparedness includes the absorbing, buffering, and response capacities; it also has been called the resilience of the society at risk, to a hazard(s). As the level of preparedness increases, the vulnerability of the community at risk decreases. Preparedness is difficult to measure. The impact of preparedness measures cannot be realised until the next event occurs or it has been shown to be of benefit during disaster drills and exercises. Hence, investments in preparedness have been relatively meager worldwide. PMID:24785814

  16. Ceres model application for increasing preparedness to climate variability in agricultural planning

    NASA Astrophysics Data System (ADS)

    Popova, Z.; Kercheva, M.

    2003-04-01

    The paper should demonstrate how knowledge of climate variability and simulation analyses over 30 years could be used to study the vulnerability of maize and wheat ecosystems in the region of Sofia. The procedure of stepwise calibration and validation of agricultural simulation CERES-maize and CERES-wheat models was used at two fields of contrastive soil conditions (Chromic Luvisol and Vertisol). Lysimeters observations under "Chromic Luvisol-maize" combination enabled to test integrally the prediction capacity of CERES-maize, including water and nitrogen fluxes at the boundaries of this vulnerable system over "1.05.1997-1.10.1999" period. The role of soil, crop, climate and irrigation scheduling (under maize only) on drought consequences and groundwater pollution was quantified for four "soil-crop" combinations by CERES models. Four water supply treatments of maize were considered on both soils: one under rainfed conditions and three with varied irrigation application. Water application in initial, development, and mid season growth stages was scheduled by CROPWAT model at any day that soil matrix suction fell to 3.0-3.2 pF with one irrigation scenario and 2.4-2.6 pF with another one. The third drainage-controlling scenario was developed on the basis of 50-75% of the required irrigation depth by satisfying most sensible phases of maize. It was established that "Chromic Luvisol -maize - dry land" combination was associated with the greatest coefficient of variability of yields (Cv=42%) and drought frequency (75% of the years with yield losses more than 20%). Average yield losses in dry vegetation seasons were 60% of the productivity potential under sufficient soil moisture. As a consequence maize cultivation under these conditions was inefficient in 20% of the years when production expenses were greater than losses. Any irrigation practice, even the drainage controlling scenario, mitigated drought consequences on risky soils as Chromic Luvisol by reducing year

  17. Dynamic Linear Model Analysis of Optical Imaging Data Acquired from the Human Neocortex

    PubMed Central

    Lavine, Michael; Haglund, Michael M.; Hochman, Daryl W.

    2011-01-01

    The amount of light absorbed and scattered by neocortical tissue is altered by neuronal activity. Imaging of intrinsic optical signals (ImIOS), a technique for mapping these activity-evoked optical changes with an imaging detector, has the potential to be useful for both clinical and experimental investigations of the human neocortex. However, its usefulness for human studies is currently limited because intraoperatively acquired ImIOS data is noisy. To improve the reliability and usefulness of ImIOS for human studies, it is desirable to find appropriate methods for the removal of noise artifacts and its statistical analysis. Here we develop a Bayesian, dynamic linear modeling approach that appears to address these problems. A dynamic linear model (DLM) was constructed that included cyclic components to model the heartbeat and respiration artifacts, and a local linear component to model the activity-evoked response. The robustness of the model was tested on a set of ImIOS data acquired from the exposed cortices of six human subjects illuminated with either 535 nm or 660 nm light. The DLM adequately reduced noise artifacts in these data while reliably preserving their activity-evoked optical responses. To demonstrate how these methods might be used for intraoperative neurosurgical mapping, optical data acquired from a single human subject during direct electrical stimulation of the cortex were quantitatively analyzed. This example showed that the DLM can be used to provide quantitative information about human ImIOS data that is not available through qualitative analysis alone. PMID:21640137

  18. Emergency Preparedness Education: An Overview.

    ERIC Educational Resources Information Center

    Stoffel, Robert, Ed.; LaValla, Patrick, Ed.

    The book is a collection of emergency preparedness instruction materials. It starts with the first chapter of "Living Life's Emergencies" by Robert Stoffel and Patrick LaValla which introduces emergency preparedness education, focusing on six major components (human body management, defensive living, time lag, disaster and civil preparedness,…

  19. Investigation of the best model to characterize diffuse correlation spectroscopy measurements acquired directly on the brain

    NASA Astrophysics Data System (ADS)

    Verdecchia, K.; Diop, M.; St. Lawrence, K.

    2015-03-01

    Diffuse correlation spectroscopy (DCS) is a non-invasive optical technique capable of monitoring tissue perfusion changes, particularly in the brain. The normalized temporal intensity autocorrelation function generated by DCS is typically characterized by assuming that the movement of erythrocytes can be modeled as a Brownian diffusion-like process instead of the expected random flow model. Carp et al. [Biomedical Optics Express, 2011] proposed a hybrid model, referred to as the hydrodynamic diffusion model, to capture both the random ballistic and diffusive nature of erythrocyte motion. The purpose of this study was to compare how well the Brownian diffusion and the hydrodynamic diffusion models characterized DCS data acquired directly on the brain, avoiding the confounding effects of scalp and skull. Data were acquired from seven pigs during normocapnia (39.9 +/- 0.7 mmHg) and hypocapnia (22.1 +/- 1.6 mmHg) with the DCS fibers placed 7 mm apart, directly on the cerebral cortex. The hydrodynamic diffusion model was found to provide a consistently better fit to the autocorrelation functions compared to the Brownian diffusion model and was less sensitive to the chosen start and end time points used in the fitting. However, the decrease in cerebral blood flow from normocapnia to hypocapnia determined was similar for the two models (-42.6 +/- 8.6 % for the Brownian model and -42.2 +/- 10.2 % for the hydrodynamic model), suggesting that the latter is reasonable for monitoring flow changes.

  20. Capable of Suicide: A Functional Model of the Acquired Capability Component of the Interpersonal-Psychological Theory of Suicide

    ERIC Educational Resources Information Center

    Smith, Phillip N.; Cukrowicz, Kelly C.

    2010-01-01

    A functional model of the acquired capability for suicide, a component of Joiner's (2005) Interpersonal-Psychological Theory of Suicide, is presented. A component of Joiner's (2005) Interpersonal-Psychological Theory of Suicide a functional model of the acquired capability for suicide is presented. The model integrates the points discussed by…

  1. [A mathematical model for the chemical control of Aedes aegypti (Diptera: Culicidae) having acquired chemical resistance].

    PubMed

    Restrepo-Alape, Leonardo D; Toro-Zapata, Hernán D; Muñoz-Loaiza, Aníbal

    2010-12-01

    Dengue fever is a common vector-borne disease in tropical and subtropical areas. It is transmitted to humans by the bite of an infected female Aedes mosquito. Since no vaccines are currently available which can protect against infection, disease control relies on controlling the mosquito population. This work was aimed at modelling such mosquito's population dynamics regarding chemical control of the adult population and its acquired resistance to chemicals. The model was analysed by using classical dynamic system theory techniques and mosquito growth threshold was determined as this establishes when a particular population may prosper in the environment or when it is likely to disappear. A suitable chemical control strategy was developed from such threshold. Simulations were made in control and non-control scenarios; this determined the degree of control application effectiveness against different levels of acquired resistance. PMID:22030690

  2. Working Together for Preparedness

    ERIC Educational Resources Information Center

    Exceptional Parent, 2006

    2006-01-01

    This article presents an interview with Daniel W. Sutherland, Officer for Civil Rights & Civil Liberties, Department of Homeland Security, to discuss some of the Department's future goals related to emergency preparedness for people with special needs and to find out how citizens can help in that quest. This article also focuses on topics such as:…

  3. Tornado Preparedness Planning.

    ERIC Educational Resources Information Center

    National Oceanic and Atmospheric Administration (DOC), Rockville, MD. National Weather Service.

    This pamphlet contains a set of guidelines for community leaders interested in developing preparedness plans for tornadoes and severe thunderstorms. Included in the guide is a list of the types of officials and agencies which should be involved in planning meetings. A set of suggestions for developing a community communications network and…

  4. Imaging the urokinase plasminongen activator receptor in preclinical breast cancer models of acquired drug resistance.

    PubMed

    LeBeau, Aaron M; Sevillano, Natalia; King, Mandy L; Duriseti, Sai; Murphy, Stephanie T; Craik, Charles S; Murphy, Laura L; VanBrocklin, Henry F

    2014-01-01

    Subtype-targeted therapies can have a dramatic impact on improving the quality and quantity of life for women suffering from breast cancer. Despite an initial therapeutic response, cancer recurrence and acquired drug-resistance are commonplace. Non-invasive imaging probes that identify drug-resistant lesions are urgently needed to aid in the development of novel drugs and the effective utilization of established therapies for breast cancer. The protease receptor urokinase plasminogen activator receptor (uPAR) is a target that can be exploited for non-invasive imaging. The expression of uPAR has been associated with phenotypically aggressive breast cancer and acquired drug-resistance. Acquired drug-resistance was modeled in cell lines from two different breast cancer subtypes, the uPAR negative luminal A subtype and the uPAR positive triple negative subtype cell line MDA-MB-231. MCF-7 cells, cultured to be resistant to tamoxifen (MCF-7 TamR), were found to significantly over-express uPAR compared to the parental cell line. uPAR expression was maintained when resistance was modeled in triple-negative breast cancer by generating doxorubicin and paclitaxel resistant MDA-MB-231 cells (MDA-MB-231 DoxR and MDA-MB-231 TaxR). Using the antagonistic uPAR antibody 2G10, uPAR was imaged in vivo by near-infrared (NIR) optical imaging and (111)In-single photon emission computed tomography (SPECT). Tumor uptake of the (111)In-SPECT probe was high in the three drug-resistant xenografts (> 46 %ID/g) and minimal in uPAR negative xenografts at 72 hours post-injection. This preclinical study demonstrates that uPAR can be targeted for imaging breast cancer models of acquired resistance leading to potential clinical applications. PMID:24505235

  5. Towards Coordination Preparedness of Soft-Target Organisation

    NASA Astrophysics Data System (ADS)

    Uddin, Mohammed Shahadat; Hossain, Liaquat

    In this paper, we introduce a network enabled coordination model to examine the coordination preparedness of soft-target organisations such as common public access areas including transit hubs, schools, parks, and sports areas. It is apparent that little attention is given in recent research focusing on the use of network analysis as a way to explore coordination preparedness for this type of organisation. In this study, we emphasise this type of soft-target organisation and propose a model to examine the coordination preparedness to any disasters by testing hypothesis related to network relationship and coordination preparedness. We analyse the dataset entitled Preparedness of Large Retail Malls to Prevent and Respond to Terrorist Attack, 2004, which contains a total of 120 completed surveys of security directors of retail malls. The following questions form the basis of this study: What do soft-target organisations need to be better prepared to respond to disaster? How does network relationship between soft-target organisation and emergency agencies affect the coordination preparedness of soft-target organisation for disaster recovery? Which degree of centrality measure needs to be followed to measure network variables in order to analyse the coordination preparedness? Result shows that soft-target organisation with high level of network relationship with other emergency agencies are better prepared to disaster response. Using this result, the preparedness of a soft-target organisation might be judged for successfully participation in an actual emergency.

  6. Influences of Preparedness Knowledge and Beliefs on Household Disaster Preparedness.

    PubMed

    Thomas, Tracy N; Leander-Griffith, Michelle; Harp, Victoria; Cioffi, Joan P

    2015-01-01

    In response to concern about strengthening the nation's ability to protect its population and way of life (i.e., security) and ability to adapt and recover from emergencies (i.e., resilience), the President of the United States issued Presidential Policy Directive 8: National Preparedness (PPD-8) (1). Signed on March 30, 2011, PPD-8 is a directive for the U.S. Department of Homeland Security to coordinate a comprehensive campaign across government, private and nonprofit sectors, and individuals to build and sustain national preparedness. Despite efforts by the Federal Emergency Management Agency (FEMA) and other organizations to educate U.S. residents on becoming prepared, growth in specific preparedness behaviors, including actions taken in advance of a disaster to be better prepared to respond to and recover, has been limited (2). In 2012, only 52% of U.S. residents surveyed by FEMA reported having supplies for a disaster (2), a decline from 57% who reported having such supplies in 2009 (3). It is believed that knowledge influences behavior, and that attitudes and beliefs, which are correlated with knowledge, might also influence behavior (4). To determine the association between knowledge and beliefs and household preparedness, CDC analyzed baseline data from Ready CDC, a personal disaster preparedness intervention piloted among Atlanta- and Morgantown-based CDC staff members during 2013–2015. Compared with persons with basic preparedness knowledge, persons with advanced knowledge were more likely to have assembled an emergency kit (44% versus 17%), developed a written household disaster plan (9% versus 4%), and received county emergency alert notifications (63% versus 41%). Similarly, differences in household preparedness behaviors were correlated with beliefs about preparedness. Persons identified as having strong beliefs in the effectiveness of disaster preparedness engaged in preparedness behaviors at levels 7%–30% higher than those with weaker

  7. Transonic Dynamics Tunnel Force and Pressure Data Acquired on the HSR Rigid Semispan Model

    NASA Technical Reports Server (NTRS)

    Schuster, David M.; Rausch, Russ D.

    1999-01-01

    This report describes the aerodynamic data acquired on the High Speed Research Rigid Semispan Model (HSR-RSM) during NASA Langley Transonic Dynamics Tunnel (TDT) Test 520 conducted from 18 March to 4 April, 1996. The purpose of this test was to assess the aerodynamic character of a rigid high speed civil transport wing. The wing was fitted with a single trailing edge control surface which was both steadily deflected and oscillated during the test to investigate the response of the aerodynamic data to steady and unsteady control motion. Angle-of-attack and control surface deflection polars at subsonic, transonic and low-supersonic Mach numbers were obtained in the tunnel?s heavy gas configuration. Unsteady pressure and steady loads data were acquired on the wing, while steady pressures were measured on the fuselage. These data were reduced using a variety of methods, programs and computer systems. The reduced data was ultimately compiled onto a CD-ROM volume which was distributed to HSR industry team members in July, 1996. This report documents the methods used to acquire and reduce the data, and provides an assessment of the quality, repeatability, and overall character of the aerodynamic data measured during this test.

  8. Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy

    PubMed Central

    Das, Subhash K.; Wang, Wang; Zhabyeyev, Pavel; Basu, Ratnadeep; McLean, Brent; Fan, Dong; Parajuli, Nirmal; DesAulniers, Jessica; Patel, Vaibhav B.; Hajjar, Roger J.; Dyck, Jason R. B.; Kassiri, Zamaneh; Oudit, Gavin Y.

    2015-01-01

    Iron-overload cardiomyopathy is a prevalent cause of heart failure on a world-wide basis and is a major cause of mortality and morbidity in patients with secondary iron-overload and genetic hemochromatosis. We investigated the therapeutic effects of resveratrol in acquired and genetic models of iron-overload cardiomyopathy. Murine iron-overload models showed cardiac iron-overload, increased oxidative stress, altered Ca2+ homeostasis and myocardial fibrosis resulting in heart disease. Iron-overload increased nuclear and acetylated levels of FOXO1 with corresponding inverse changes in SIRT1 levels in the heart corrected by resveratrol therapy. Resveratrol, reduced the pathological remodeling and improved cardiac function in murine models of acquired and genetic iron-overload at varying stages of iron-overload. Echocardiography and hemodynamic analysis revealed a complete normalization of iron-overload mediated diastolic and systolic dysfunction in response to resveratrol therapy. Myocardial SERCA2a levels were reduced in iron-overloaded hearts and resveratrol therapy restored SERCA2a levels and corrected altered Ca2+ homeostasis. Iron-mediated pro-oxidant and pro-fibrotic effects in human and murine cardiomyocytes and cardiofibroblasts were suppressed by resveratrol which correlated with reduction in iron-induced myocardial oxidative stress and myocardial fibrosis. Resveratrol represents a clinically and economically feasible therapeutic intervention to reduce the global burden from iron-overload cardiomyopathy at early and chronic stages of iron-overload. PMID:26638758

  9. Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.

    PubMed

    Das, Subhash K; Wang, Wang; Zhabyeyev, Pavel; Basu, Ratnadeep; McLean, Brent; Fan, Dong; Parajuli, Nirmal; DesAulniers, Jessica; Patel, Vaibhav B; Hajjar, Roger J; Dyck, Jason R B; Kassiri, Zamaneh; Oudit, Gavin Y

    2015-01-01

    Iron-overload cardiomyopathy is a prevalent cause of heart failure on a world-wide basis and is a major cause of mortality and morbidity in patients with secondary iron-overload and genetic hemochromatosis. We investigated the therapeutic effects of resveratrol in acquired and genetic models of iron-overload cardiomyopathy. Murine iron-overload models showed cardiac iron-overload, increased oxidative stress, altered Ca(2+) homeostasis and myocardial fibrosis resulting in heart disease. Iron-overload increased nuclear and acetylated levels of FOXO1 with corresponding inverse changes in SIRT1 levels in the heart corrected by resveratrol therapy. Resveratrol, reduced the pathological remodeling and improved cardiac function in murine models of acquired and genetic iron-overload at varying stages of iron-overload. Echocardiography and hemodynamic analysis revealed a complete normalization of iron-overload mediated diastolic and systolic dysfunction in response to resveratrol therapy. Myocardial SERCA2a levels were reduced in iron-overloaded hearts and resveratrol therapy restored SERCA2a levels and corrected altered Ca(2+) homeostasis. Iron-mediated pro-oxidant and pro-fibrotic effects in human and murine cardiomyocytes and cardiofibroblasts were suppressed by resveratrol which correlated with reduction in iron-induced myocardial oxidative stress and myocardial fibrosis. Resveratrol represents a clinically and economically feasible therapeutic intervention to reduce the global burden from iron-overload cardiomyopathy at early and chronic stages of iron-overload. PMID:26638758

  10. Emergency preparedness in obstetrics.

    PubMed

    Haeri, Sina; Marcozzi, David

    2015-04-01

    During and after disasters, focus is directed toward meeting the immediate needs of the general population. As a result, the routine health care and the special needs of some vulnerable populations such as pregnant and postpartum women may be overlooked within a resource-limited setting. In the event of hazards such as natural disasters, manmade disasters, and terrorism, knowledge of emergency preparedness strategies is imperative for the pregnant woman and her family, obstetric providers, and hospitals. Individualized plans for the pregnant woman and her family should include knowledge of shelter in place, birth at home, and evacuation. Obstetric providers need to have a personal disaster plan in place that accounts for work responsibilities in case of an emergency and business continuity strategies to continue to provide care to their communities. Hospitals should have a comprehensive emergency preparedness program utilizing an "all hazards" approach to meet the needs of pregnant and postpartum women and other vulnerable populations during disasters. With lessons learned in recent tragedies such as Hurricane Katrina in mind, we hope this review will stimulate emergency preparedness discussions and actions among obstetric providers and attenuate adverse outcomes related to catastrophes in the future. PMID:25751222

  11. [Acquired dyslexias and dysgraphias under the prism of cognitive neuropsychology: a model for the Spanish language].

    PubMed

    Böhm, P; Diéguez-Vide, F; Peña-Casanova, J; Tainturier, M J; Lecours, A R

    2000-02-01

    The present paper discusses the different clinical manifestations of acquired disorders of reading and writing from a neurocognitive viewpoint. Based on a specific functional architecture of reading and writing--a cognitive model; presented as well--the different syndromes of acquired dyslexias and dysgraphias, that have been described in the specialized literature during the last 25 years, will be reviewed. The different pathologies are distributed along three different functional axes: a plurimodal component, including the semantic system, for the description of peripheric disorders of reading and writing; a lexical block which is justified by the findings in patients with surface dyslexia/dysgraphia; and a third, sublexical component, in order to illustrate the different functional impairments in phonological dyslexia/dysgraphia. Following the description of syndromes due to selective "functional lesions", we discuss deep dyslexia/dysgraphia, a syndrome due to multiple functional lesions. All of the syndromes will be justified and discussed with respect to the different components of the functional architecture presented and are based on cases of the literature and personal observations. Concluding remarks will evaluate the new insights gained by the presented functional arquitecture in relation to other cognitive models for the analysis of reading aloud and writing to dictation of single words. PMID:10769534

  12. A Convenient Cell Culture Model for CML Acquired Resistance Through BCR-ABL Mutations.

    PubMed

    Wang, Zhiqiang; Chen, WenYong

    2016-01-01

    Tyrosine kinase inhibitors (TKIs) are the effective treatments for chronic myeloid leukemia (CML). However, clinical resistance to TKIs that leads to patient relapse remains a challenge. Acquisition of BCR-ABL mutations is crucial in the resistance but the underlying molecular mechanisms are poorly understood. Here we describe a cell culture model for CML acquired resistance in which blast crisis CML cells undergo initial apoptosis upon treatment with therapeutically effective doses of TKIs, but the cells regrow quickly with development of resistance through BCR-ABL mutations. This model mimics the clinical process of acquisition of BCR-ABL mutations and will be an important tool to dissect molecular mechanisms of CML drug resistance and to explore strategies to overcome resistance. PMID:27581146

  13. Etiology matters – Genomic DNA Methylation Patterns in Three Rat Models of Acquired Epilepsy

    PubMed Central

    Dębski, Konrad J.; Pitkanen, Asla; Puhakka, Noora; Bot, Anna M.; Khurana, Ishant; Harikrishnan, KN; Ziemann, Mark; Kaspi, Antony; El-Osta, Assam; Lukasiuk, Katarzyna; Kobow, Katja

    2016-01-01

    This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA methylation changes independent of etiology. We investigated DNA methylation and gene expression in the hippocampal CA3/dentate gyrus fields at 3 months following epileptogenic injury in three experimental models of epilepsy: focal amygdala stimulation, systemic pilocarpine injection, or lateral fluid-percussion induced traumatic brain injury (TBI) in rats. In the models studies, DNA methylation and gene expression profiles distinguished controls from injured animals. We observed consistent increased methylation in gene bodies and hypomethylation at non-genic regions. We did not find a common methylation signature in all three different models and few regions common to any two models. Our data provide evidence that genome-wide alteration of DNA methylation signatures is a general pathomechanism associated with epileptogenesis and epilepsy in experimental animal models, but the broad pathophysiological differences between models (i.e. pilocarpine, amygdala stimulation, and post-TBI) are reflected in distinct etiology-dependent DNA methylation patterns. PMID:27157830

  14. Classifying Korean Adolescents' Career Preparedness

    ERIC Educational Resources Information Center

    Lee, In Heok; Rojewski, Jay W.; Hill, Roger B.

    2013-01-01

    Latent class analysis was used to examine the career preparation of 5,227 11th-grade Korean adolescents taken from the Korean Education Longitudinal Study of 2005 (KELS:2005). Three career preparedness groups were identified, to reflecting Skorikov's ("J Vocat Behav" 70:8-24, 2007) conceptualization of career preparedness: prepared, confused, and…

  15. A causal model of post-traumatic stress disorder: disentangling predisposed from acquired neural abnormalities.

    PubMed

    Admon, Roee; Milad, Mohammed R; Hendler, Talma

    2013-07-01

    Discriminating neural abnormalities into the causes versus consequences of psychopathology would enhance the translation of neuroimaging findings into clinical practice. By regarding the traumatic encounter as a reference point for disease onset, neuroimaging studies of post-traumatic stress disorder (PTSD) can potentially allocate PTSD neural abnormalities to either predisposing (pre-exposure) or acquired (post-exposure) factors. Based on novel research strategies in PTSD neuroimaging, including genetic, environmental, twin, and prospective studies, we provide a causal model that accounts for neural abnormalities in PTSD, and outline its clinical implications. Current data suggest that abnormalities within the amygdala and dorsal anterior cingulate cortex represent predisposing risk factors for developing PTSD, whereas dysfunctional hippocampal-ventromedial prefrontal cortex (vmPFC) interactions may become evident only after having developed the disorder. PMID:23768722

  16. First Experimental In Vivo Model of Enhanced Dengue Disease Severity through Maternally Acquired Heterotypic Dengue Antibodies

    PubMed Central

    Ng, Jowin Kai Wei; Zhang, Summer Lixin; Tan, Hwee Cheng; Yan, Benedict; Maria Martinez Gomez, Julia; Tan, Wei Yu; Lam, Jian Hang; Tan, Grace Kai Xin; Ooi, Eng Eong; Alonso, Sylvie

    2014-01-01

    Dengue (DEN) represents the most serious arthropod-borne viral disease. DEN clinical manifestations range from mild febrile illness to life-threatening hemorrhage and vascular leakage. Early epidemiological observations reported that infants born to DEN-immune mothers were at greater risk to develop the severe forms of the disease upon infection with any serotype of dengue virus (DENV). From these observations emerged the hypothesis of antibody-dependent enhancement (ADE) of disease severity, whereby maternally acquired anti-DENV antibodies cross-react but fail to neutralize DENV particles, resulting in higher viremia that correlates with increased disease severity. Although in vitro and in vivo experimental set ups have indirectly supported the ADE hypothesis, direct experimental evidence has been missing. Furthermore, a recent epidemiological study has challenged the influence of maternal antibodies in disease outcome. Here we have developed a mouse model of ADE where DENV2 infection of young mice born to DENV1-immune mothers led to earlier death which correlated with higher viremia and increased vascular leakage compared to DENV2-infected mice born to dengue naïve mothers. In this ADE model we demonstrated the role of TNF-α in DEN-induced vascular leakage. Furthermore, upon infection with an attenuated DENV2 mutant strain, mice born to DENV1-immune mothers developed lethal disease accompanied by vascular leakage whereas infected mice born to dengue naïve mothers did no display any clinical manifestation. In vitro ELISA and ADE assays confirmed the cross-reactive and enhancing properties towards DENV2 of the serum from mice born to DENV1-immune mothers. Lastly, age-dependent susceptibility to disease enhancement was observed in mice born to DENV1-immune mothers, thus reproducing epidemiological observations. Overall, this work provides direct in vivo demonstration of the role of maternally acquired heterotypic dengue antibodies in the enhancement of dengue

  17. Energy emergency preparedness

    SciTech Connect

    Barnes, B.K.; Rothkopf, M.H.

    1988-06-01

    Energy emergency preparedness is the special responsibility of the Deputy Assistant Secretary of Energy Emergencies within the Office of the Assistant Secretary for International Affairs and Energy Emergencies; though other Department of Energy (DOE) offices manage some aspects and DOE also coordinates emergency management with other federal departments. There are two basic objectives for energy emergency preparedness. The first of these, the economic stabilization objective, seeks to ease the impact of an energy supply disruption by facilitating a quick recovery and minimizing the disruption's economic consequences. The second is the mobilization support objective to ensure that there is adequate energy and fuel to support defense, defense industrial and critical civilian needs for energy and fuel. While all energy systems are vulnerable they vary in the degree of seriousness and the probability of a disruption. Oil is the most vulnerable, and will become increasingly so in the 1990's, as domestic and reliable foreign sources diminish and the United States relies more on imports from volatile Persian Gulf countries. Electric power is the next most vulnerable system, being open particularly to multi-site terrorist attack. This overview examines two highly connected organizations: the Office of Energy Emergencies (OEE) itself and the actual response organization, centering on the Energy Emergency Management System (EEMS). 38 refs., 10 figs.

  18. National Veterans Health Administration inpatient risk stratification models for hospital-acquired acute kidney injury

    PubMed Central

    Cronin, Robert M; VanHouten, Jacob P; Siew, Edward D; Eden, Svetlana K; Fihn, Stephan D; Nielson, Christopher D; Peterson, Josh F; Baker, Clifton R; Ikizler, T Alp; Speroff, Theodore

    2015-01-01

    Objective Hospital-acquired acute kidney injury (HA-AKI) is a potentially preventable cause of morbidity and mortality. Identifying high-risk patients prior to the onset of kidney injury is a key step towards AKI prevention. Materials and Methods A national retrospective cohort of 1,620,898 patient hospitalizations from 116 Veterans Affairs hospitals was assembled from electronic health record (EHR) data collected from 2003 to 2012. HA-AKI was defined at stage 1+, stage 2+, and dialysis. EHR-based predictors were identified through logistic regression, least absolute shrinkage and selection operator (lasso) regression, and random forests, and pair-wise comparisons between each were made. Calibration and discrimination metrics were calculated using 50 bootstrap iterations. In the final models, we report odds ratios, 95% confidence intervals, and importance rankings for predictor variables to evaluate their significance. Results The area under the receiver operating characteristic curve (AUC) for the different model outcomes ranged from 0.746 to 0.758 in stage 1+, 0.714 to 0.720 in stage 2+, and 0.823 to 0.825 in dialysis. Logistic regression had the best AUC in stage 1+ and dialysis. Random forests had the best AUC in stage 2+ but the least favorable calibration plots. Multiple risk factors were significant in our models, including some nonsteroidal anti-inflammatory drugs, blood pressure medications, antibiotics, and intravenous fluids given during the first 48 h of admission. Conclusions This study demonstrated that, although all the models tested had good discrimination, performance characteristics varied between methods, and the random forests models did not calibrate as well as the lasso or logistic regression models. In addition, novel modifiable risk factors were explored and found to be significant. PMID:26104740

  19. Emergency preparedness: one community's response.

    PubMed

    Glick, Doris F; Jerome-D'Emilia, Bonnie; Nolan, Mary Anne; Burke, Pamela

    2004-01-01

    Since 2001, our nations' leaders, the press, and the general public have looked to the health sector for leadership in addressing acts of terrorism. It has become urgent for health agencies and related public services to collaborate and for all health professionals to become knowledgeable about disaster preparedness. This article describes collaboration between the public health department, local hospitals and the school of nursing in one community, Charlottesville, Virginia, to address disaster preparedness. In this story about our community's emergency preparedness, the focus is both on preparation and the hope we will never need to utilize this knowledge. PMID:15596974

  20. Chronic beryllium disease: an updated model interaction between innate and acquired immunity.

    PubMed

    Sawyer, Richard T; Maier, Lisa A

    2011-02-01

    During the last decade, there have been concerted efforts to reduce beryllium (Be) exposure in the workplace and thereby reduce potential cases of this occupational lung disorder. Despite these efforts, it is estimated that there are at least one million Be-exposed individuals in the U.S. who are potentially at risk for developing chronic beryllium disease (CBD). Previously, we reviewed the current CBD literature and proposed that CBD represents a model interaction between innate and acquired immunity (Sawyer et al., Int Immunopharmacol 2:249-261, 2002). We closed this review with a section on "future directions" that identified key gaps in our understanding of the pathogenesis of CBD. In the intervening period, progress has been made to fill in some of these gaps, and the current review will provide an update on that progress. Based on recent findings, we provide a new hypothesis to explain how Be drives sustained chronic inflammation and granuloma formation in CBD leading to progressive compromised lung function in CBD patients. This paradigm has direct implications for our understanding of the development of an immune response to Be, but is also likely applicable to other immune-mediated lung diseases of known and unknown etiology. PMID:20981472

  1. Assessment of the best flow model to characterize diffuse correlation spectroscopy data acquired directly on the brain.

    PubMed

    Verdecchia, Kyle; Diop, Mamadou; Morrison, Laura B; Lee, Ting-Yim; St Lawrence, Keith

    2015-11-01

    Diffuse correlation spectroscopy (DCS) is a non-invasive optical technique capable of monitoring tissue perfusion. The normalized temporal intensity autocorrelation function generated by DCS is typically characterized by assuming that the movement of erythrocytes can be modeled as a Brownian diffusion-like process instead of by the expected random flow model. Recently, a hybrid model, referred to as the hydrodynamic diffusion model, was proposed, which combines the random and Brownian flow models. The purpose of this study was to investigate the best model to describe autocorrelation functions acquired directly on the brain in order to avoid confounding effects of extracerebral tissues. Data were acquired from 11 pigs during normocapnia and hypocapnia, and flow changes were verified by computed tomography perfusion (CTP). The hydrodynamic diffusion model was found to provide the best fit to the autocorrelation functions; however, no significant difference for relative flow changes measured by the Brownian and hydrodynamic diffusion models was observed. PMID:26600995

  2. Emergency preparedness for home healthcare providers.

    PubMed

    Ruder, Shirley

    2012-06-01

    Unfortunately, disasters occur. We cannot always know the effects ahead of time, but we do know that lives can be lost, property damaged, and public health and home care agencies may not be able to provide the normal standard of care. Studies have shown that disaster preparedness content is limited in U.S. nursing programs (). Given the magnitude of recent natural disasters, such as the Japanese earthquake and tsunami in 2011, these findings are alarming. The increasing demands on healthcare providers in response to emergencies force home healthcare clinicians to identify their roles and responsibilities in emergency preparedness. This article discusses 1 model of disaster response and the role of the home healthcare provider at each stage. It further guides home healthcare nurses in creating a personal and professional plan, enabling them to understand how to minimize the impact of disasters and address the needs of their patients and those close to them. PMID:21987023

  3. Cyber Security Domestic Preparedness Act

    THOMAS, 111th Congress

    Rep. Rodriguez, Ciro D. [D-TX-23

    2010-01-26

    01/28/2010 Referred to the Subcommittee on Emergency Communications, Preparedness, and Response. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. Experimental Space Shuttle Orbiter Studies to Acquire Data for Code and Flight Heating Model Validation

    NASA Technical Reports Server (NTRS)

    Wadhams, T. P.; Holden, M. S.; MacLean, M. G.; Campbell, Charles

    2010-01-01

    In an experimental study to obtain detailed heating data over the Space Shuttle Orbiter, CUBRC has completed an extensive matrix of experiments using three distinct models and two unique hypervelocity wind tunnel facilities. This detailed data will be employed to assess heating augmentation due to boundary layer transition on the Orbiter wing leading edge and wind side acreage with comparisons to computational methods and flight data obtained during the Orbiter Entry Boundary Layer Flight Experiment and HYTHIRM during STS-119 reentry. These comparisons will facilitate critical updates to be made to the engineering tools employed to make assessments about natural and tripped boundary layer transition during Orbiter reentry. To achieve the goals of this study data was obtained over a range of Mach numbers from 10 to 18, with flight scaled Reynolds numbers and model attitudes representing key points on the Orbiter reentry trajectory. The first of these studies were performed as an integral part of Return to Flight activities following the accident that occurred during the reentry of the Space Shuttle Columbia (STS-107) in February of 2003. This accident was caused by debris, which originated from the foam covering the external tank bipod fitting ramps, striking and damaging critical wing leading edge heating tiles that reside in the Orbiter bow shock/wing interaction region. During investigation of the accident aeroheating team members discovered that only a limited amount of experimental wing leading edge data existed in this critical peak heating area and a need arose to acquire a detailed dataset of heating in this region. This new dataset was acquired in three phases consisting of a risk mitigation phase employing a 1.8% scale Orbiter model with special temperature sensitive paint covering the wing leading edge, a 0.9% scale Orbiter model with high resolution thin-film instrumentation in the span direction, and the primary 1.8% scale Orbiter model with detailed

  5. A molecular model for the mechanism of acquired tamoxifen resistance in breast cancer

    PubMed Central

    Fan, Ping; Agboke, Fadeke A.; Cunliffe, Heather E.; Ramos, Pilar; Jordan, V. Craig

    2014-01-01

    Purpose: Estrogen (E2)-stimulated growth re-emerges after a c-Src inhibitor blocking E2-induced apoptosis. A resulting cell line, MCF-7:PF, is selected with features of functional estrogen receptor (ER) and over-expression of insulin-like growth factor-1 receptor beta (IGF-1Rβ). We addressed the question of whether the selective ER modulator (SERM), 4-hydroxytamoxifen (4-OHT) or other SERMs could target ER to prevent E2-stimulated growth in MCF-7:PF cells. Methods: Protein levels of receptors and signaling pathways were examined by immunoblotting. Expression of mRNA was measured through real-time RT-PCR. Recruitment of ER or nuclear receptor coactivator 3 (SRC3) to the promoter of ER-target gene was detected by chromatin-immunoprecipitation (ChIP). Results: 4-OHT and other SERMs stimulated cell growth in an ER-dependent manner. However, unlike E2, 4-OHT suppressed classical ER-target genes as does the pure antiestrogen ICI 182,780 (ICI). ChIP assay indicated that 4-OHT did not recruit ER or SRC3 to the promoter of ER-target gene, pS2. Paradoxically, 4-OHT reduced total IGF-1Rβ but increased phosphorylation of IGF-1Rβ. Mechanistic studies revealed that 4-OHT functioned as an agonist to enhance the non-genomic activity of ER and activate focal adhesion molecules to further increase phosphorylation of IGF-1Rβ. Disruption of membrane-associated signaling, IGF-1R and focal adhesion kinase (FAK), completely abolished 4-OHT-stimulated cell growth. Conclusions: This study is the first to recapitulate a cellular model in vitro of acquired tamoxifen resistance developed in athymic mice in vivo. Importantly, it provides a rationale that membrane-associated pathways may be valuable therapeutic targets for tamoxifen resistant patients in clinic. PMID:25204804

  6. Interventions based on the multiple connections model of reading for developmental dyslexia and acquired deep dyslexia.

    PubMed

    Berninger, V W; Lester, K; Sohlberg, M M; Mateer, C

    1991-01-01

    This paper deals with intervention strategies for developmental and acquired dyslexia. In Study 1 two alternative strategies for developmental surface dyslexia (dysfunctional connection between the whole word orthographic code and the phonetic or name code) were compared. In both the initial study and replication study, a modification of the selective reminding technique was superior to a traditional multisensory technique in beginning readers, presumably because it facilitated word finding or prelexical access to a phonetic code. In Study 2 an adolescent with acquired deep dyslexia (dysfunctional connection between letter and phonemic codes) who had had his angular gyrus (site of grapheme-phoneme correspondence) surgically removed, recovered reading function after a four-month phonemic analysis training program. Further research is needed to evaluate the efficacy of theory-based intervention strategies in children with developmental reading disorders unrelated to focal lesions and in adults with acquired reading disorders related to focal lesions. PMID:14589528

  7. Capable of Suicide: A Functional Model of the Acquired Capability Component of the Interpersonal-Psychological Theory of Suicide

    PubMed Central

    Smith, Phillip N.; Cukrowicz, Kelly C.

    2016-01-01

    The current review aims to present a functional model of the acquired capability for suicide; a component of Joiner’s (2005) Interpersonal-Psychological Theory of Suicide. This review is aimed at integrating the points discussed by Joiner into a unified and specific conceptualization of acquired capability. Additionally, we offer some points of elaboration; such as the interaction between specific diatheses with life events, the role of short-term bolstering of the capability for suicide, and how contextual factors moderate the experience of painful and provocative life events; thereby leading to fearlessness and pain insensitivity to the actions and ideas involved in suicide. PMID:20560748

  8. Words and Maps: Developmental Changes in Mental Models of Spatial Information Acquired from Descriptions and Depictions

    ERIC Educational Resources Information Center

    Uttal, David H.; Fisher, Joan A.; Taylor, Holly A.

    2006-01-01

    People acquire spatial information from many sources, including maps, verbal descriptions, and navigating in the environment. The different sources present spatial information in different ways. For example, maps can show many spatial relations simultaneously, but in a description, each spatial relation must be presented sequentially. The present…

  9. Maternal Modeling and the Acquisition of Fear and Avoidance in Toddlers: Influence of Stimulus Preparedness and Child Temperament

    ERIC Educational Resources Information Center

    Dubi, Kathrin; Rapee, Ronald M.; Emerton, Jane L.; Schniering, Carolyn A.

    2008-01-01

    The aim of the present study was to investigate the influence of maternal modeling on the acquisition of fear and avoidance towards fear-relevant and fear-irrelevant, novel stimuli in a sample of 71 toddlers. Children were shown a rubber snake or spider (fear-relevant objects) and a rubber mushroom or flower (fear-irrelevant objects), which were…

  10. "High Schools That Work" and College Preparedness: Measuring the Model's Impact on Mathematics and Science Pipeline Progression

    ERIC Educational Resources Information Center

    Miller, Luke C.; Mittleman, Joel

    2012-01-01

    The "High Schools That Work" school improvement initiative is the nation's largest comprehensive school reform model with over a thousand schools adopting its framework. The initiative's premise is that all students can meet the demands of a college preparatory curriculum if provided the right supports. Analyzing over a decade of data on student…

  11. Logic Modeling as a Tool to Prepare to Evaluate Disaster and Emergency Preparedness, Response, and Recovery in Schools

    ERIC Educational Resources Information Center

    Zantal-Wiener, Kathy; Horwood, Thomas J.

    2010-01-01

    The authors propose a comprehensive evaluation framework to prepare for evaluating school emergency management programs. This framework involves a logic model that incorporates Government Performance and Results Act (GPRA) measures as a foundation for comprehensive evaluation that complements performance monitoring used by the U.S. Department of…

  12. The National Atmospheric Release Advisory Center (NARAC) Modeling and Decision Support System for Radiological and Nuclear Emergency Preparedness and Response

    SciTech Connect

    Nasstrom, J S; Sugiyama, G; Baskett, R; Larsen, S; Bradley, M

    2005-04-01

    This paper describes the tools and services provided by the National Atmospheric Release Advisory Center (NARAC) at Lawrence Livermore National Laboratory (LLNL) for modeling the impacts of airborne hazardous materials. NARAC provides atmospheric plume modeling tools and services for chemical, biological, radiological, and nuclear airborne hazards. NARAC can simulate downwind effects from a variety of scenarios, including fires, industrial and transportation accidents, radiation dispersal device explosions, hazardous material spills, sprayers, nuclear power plant accidents, and nuclear detonations. NARAC collaborates with several government agencies and laboratories in order to accomplish its mission. The NARAC suite of software tools include simple stand-alone, local-scale plume modeling tools for end-user's computers, and Web- and Internet-based software to access advanced modeling tools and expert analyses from the national center at LLNL. Initial automated, 3-D predictions of plume exposure limits and protective action guidelines for emergency responders and managers are available from the center in 5-10 minutes. These can be followed immediately by quality-assured, refined analyses by 24 x 7 on-duty or on-call NARAC staff. NARAC continues to refine calculations using updated on-scene information, including measurements, until all airborne releases have stopped and the hazardous threats are mapped and impacts assessed. Model predictions include the 3-D spatial and time-varying effects of weather, land use, and terrain, on scales from the local to regional to global. Real-time meteorological data and forecasts are provided by redundant communications links to the U.S. National Oceanic and Atmospheric Administration (NOAA), U.S. Navy, and U.S. Air Force, as well as an in-house mesoscale numerical weather prediction model. NARAC provides an easy-to-use Geographical Information System (GIS) for display of plume predictions with affected population counts and

  13. Does Classroom Management Coursework Influence Pre-service Teachers' Perceived Preparedness or Confidence?

    ERIC Educational Resources Information Center

    O'Neill, Sue; Stephenson, Jennifer

    2012-01-01

    There has been conjecture that completing focused coursework units on classroom management during pre-service teacher preparation might lead to increased feelings of preparedness and confidence. This study reports the preparedness in managing specific problem behaviours, familiarity, and confidence in using management strategies and models of…

  14. Quality control of meteorological data for the chemical stockpile emergency preparedness program.

    SciTech Connect

    Liljegren, J.C.; Tschopp, S.; Rogers, K.; Wasmer, F.; Liljegren, L.; Myirski, M.; Decision and Information Sciences; U.S. Army Chemical Materials Agency

    2009-08-01

    The Chemical Stockpile Emergency Preparedness Program Meteorological Support Project ensures the accuracy and reliability of data acquired by meteorological monitoring stations located at seven U.S. Army chemical weapons depots where storage and weapons destruction (demilitarization) activities are ongoing. The data are delivered in real time to U.S. Army plume dispersion models, which are used to plan for and respond to a potential accidental release of a chemical weapons agent. The project provides maintenance, calibration, and audit services for the instrumentation; collection, automated screening, visual inspection, and analysis of the data; and problem reporting and tracking to carefully control the data quality. The resulting high-quality meteorological data enhance emergency response modeling and public safety.

  15. Acquired hyperpigmentations*

    PubMed Central

    Cestari, Tania Ferreira; Dantas, Lia Pinheiro; Boza, Juliana Catucci

    2014-01-01

    Cutaneous hyperpigmentations are frequent complaints, motivating around 8.5% of all dermatological consultations in our country. They can be congenital, with different patterns of inheritance, or acquired in consequence of skin problems, systemic diseases or secondary to environmental factors. The vast majority of them are linked to alterations on the pigment melanin, induced by different mechanisms. This review will focus on the major acquired hyperpigmentations associated with increased melanin, reviewing their mechanisms of action and possible preventive measures. Particularly prominent aspects of diagnosis and therapy will be emphasized, with focus on melasma, post-inflammatory hyperpigmentation, periorbital pigmentation, dermatosis papulosa nigra, phytophotodermatoses, flagellate dermatosis, erythema dyschromicum perstans, cervical poikiloderma (Poikiloderma of Civatte), acanthosis nigricans, cutaneous amyloidosis and reticulated confluent dermatitis PMID:24626644

  16. Assessing School Emergency Care Preparedness.

    ERIC Educational Resources Information Center

    Hale, Charles; Varnes, Jill

    A study assessed the emergency health care preparedness of a north central Florida public school district in light of seven criteria: (1) school policies regarding delivery of emergency health care; (2) identification of school personnel responsible for rendering emergency care; (3) training levels of emergency health care providers (first aid and…

  17. One Health and emergency preparedness.

    PubMed

    Stauffer, Kendra E; Conti, Lisa

    2014-11-01

    Emergencies such as hurricanes, floods and nuclear disasters do not just affect people and the environment; they also affect domestic animals. In this latest article in Veterinary Record's One Health series, Kendra Stauffer and Lisa Conti discuss how One Health considerations are being incorporated into emergency preparedness planning in the USA. PMID:25359746

  18. Earthquake Preparedness Checklist for Schools.

    ERIC Educational Resources Information Center

    1999

    A brochure provides a checklist highlighting the important questions and activities that should be addressed and undertaken as part of a school safety and preparedness program for earthquakes. It reminds administrators and other interested parties on what not to forget in preparing schools for earthquakes, such as staff knowledge needs, evacuation…

  19. Emergency Preparedness: Are You Ready?

    ERIC Educational Resources Information Center

    Harley, Lorraine

    2012-01-01

    Most Americans who consider emergency preparedness think of someone or another country attacking the United States. Most newspaper and televised accounts involve community leaders and policymakers preparing for a terrorist attack. However, anyone who operates a child care center, family child care home, or has children of her own, knows that…

  20. Principles of Emergency Preparedness Planning.

    ERIC Educational Resources Information Center

    Hindman, R. Eugene, Jr.

    1985-01-01

    Steps and considerations in developing an institutional plan for emergency preparedness are discussed, including delineation of internal and external responsibilities, warning systems, a means for activating the plan, a command headquarters, medical facilities, housing and food, internal and external communications, transportation, and testing and…

  1. Towards an Age-Dependent Transmission Model of Acquired and Sporadic Creutzfeldt-Jakob Disease

    PubMed Central

    de Pedro-Cuesta, Jesús; Mahillo-Fernandez, Ignacio; Calero, Miguel; Rábano, Alberto; Cruz, Mabel; Siden, Åke; Martínez-Martín, Pablo; Laursen, Henning; Ruiz-Tovar, María; Mølbak, Kåre

    2014-01-01

    Introduction Sporadic Creutzfeldt-Jakob disease (sCJD) might be transmitted by surgery. The purpose of this study was to investigate potential susceptibility to sCJD from surgery at juvenile age and in early adulthood. Methods From Danish and Swedish national registries we identified 167 definite and probable sCJD cases with onset from 1987 through 2003, and 835 age-, sex- and residence-matched controls along with their surgical histories. Main, anatomically or etiologically classified surgical procedures followed by a ≥20-year lag were analyzed using logistic regression, and stratified by age at first-registered surgical discharge. Results The risk of having a diagnosis of CJD depended strongly on age at first surgery with odds ratio (OR) of 12.80 (95% CI 2.56–64.0) in patients <30 years, 3.04 (95% 1.26–7.33) in 30–39 years, and 1.75 (95% CI 0.89–3.45) in ≥40 years, for anatomically classified surgical procedures. Similar figures were obtained for etiologically classified surgical procedures. Conclusions Risk of surgical-acquired sCJD depends on age at exposure; this pattern is similar to age-specific profiles reported for CJD accidentally transmitted by human pituitary-derived growth hormone and susceptibility curves for variant CJD estimated after adjustment for dietary exposure to bovine spongiform encephalopathy. There might be an age-at-exposure-related susceptibility to acquire all CJD forms, including sCJD from routine surgery. PMID:25279832

  2. Novice Teachers' Perceptions of Preparedness to Teach by Certification Route

    ERIC Educational Resources Information Center

    Wooten, Karen E.

    2009-01-01

    The purpose of this study was to examine the effects of certification route (traditional versus non-traditional) on second-year, core content area (English, mathematics, science, and social studies) high school teachers' perceptions of their preparedness to teach. The curricular model for teacher preparation proposed by Feiman-Nemser (2001) served…

  3. Modelling Temporal Stability of EPI Time Series Using Magnitude Images Acquired with Multi-Channel Receiver Coils

    PubMed Central

    Hutton, Chloe; Balteau, Evelyne; Lutti, Antoine; Josephs, Oliver; Weiskopf, Nikolaus

    2012-01-01

    In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR) of an EPI time series as a function of image SNR (SNR0). This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforward because it requires export and reconstruction of large amounts of k-space raw data and detailed, custom-made image reconstruction methods. Here we present a simple extension to the model that allows characterization of the temporal noise properties of EPI time series acquired with multi-channel receiver coils, and reconstructed with standard root-sum-of-squares combination, without the need for raw data or custom-made image reconstruction. The proposed extended model includes an additional parameter κ which reflects the impact of noise correlations between receiver channels on the data and scales an apparent image SNR (SNR′0) measured directly from root-sum-of-squares reconstructed magnitude images so that κ = SNR′0/SNR0 (under the condition of SNR0>50 and number of channels ≤32). Using Monte Carlo simulations we show that the extended model parameters can be estimated with high accuracy. The estimation of the parameter κ was validated using an independent measure of the actual SNR0 for non-accelerated phantom data acquired at 3T with a 32-channel receiver coil. We also demonstrate that compared to the original model the extended model results in an improved fit to human task-free non-accelerated fMRI data acquired at 7T with a 24-channel receiver coil. In particular, the extended model improves the prediction of low to medium tSNR values and so can play an important role in the optimization of high-resolution fMRI experiments at lower SNR levels. PMID:23284874

  4. Tsunami Preparedness in Washington (video)

    USGS Publications Warehouse

    2010-01-01

    Tsunamis are a constant threat to the coasts of our world. Although tsunamis are infrequent along the West coast of the United States, it is possible and necessary to prepare for potential tsunami hazards to minimize loss of life and property. Community awareness programs are important, as they strive to create an informed society by providing education and training. This video about tsunami preparedness in Washington distinguishes between a local tsunami and a distant event and focus on the specific needs of this region. It offers guidelines for correct tsunami response and community preparedness from local emergency managers, first-responders, and leading experts on tsunami hazards and warnings, who have been working on ways of making the tsunami affected regions safer for the people and communities on a long-term basis. This video was produced by the US Geological Survey (USGS) in cooperation with Washington Emergency Management Division (EMD) and with funding by the National Tsunami Hazard Mitigation Program.

  5. Tsunami Preparedness in Oregon (video)

    USGS Publications Warehouse

    Filmed and edited by: Loeffler, Kurt; Gesell, Justine

    2010-01-01

    Tsunamis are a constant threat to the coasts of our world. Although tsunamis are infrequent along the West coast of the United States, it is possible and necessary to prepare for potential tsunami hazards to minimize loss of life and property. Community awareness programs are important, as they strive to create an informed society by providing education and training. This video about tsunami preparedness in Oregon distinguishes between a local tsunami and a distant event and focus on the specific needs of this region. It offers guidelines for correct tsunami response and community preparedness from local emergency managers, first-responders, and leading experts on tsunami hazards and warnings, who have been working on ways of making the tsunami affected regions safer for the people and communities on a long-term basis. This video was produced by the US Geological Survey (USGS) in cooperation with Oregon Department of Geology and Mineral Industries (DOGAMI).

  6. An Academic-Government-Faith Partnership to Build Disaster Mental Health Preparedness and Community Resilience

    PubMed Central

    Semon, Natalie L.; Lating, Jeffrey M.; Everly, George S.; Perry, Charlene J.; Moore, Suzanne Straub; Mosley, Adrian M.; Thompson, Carol B.; Links, Jonathan M.

    2014-01-01

    Objectives Faculty and affiliates of the Johns Hopkins Preparedness and Emergency Response Research Center partnered with local health departments and faith-based organizations to develop a dual-intervention model of capacity-building for public mental health preparedness and community resilience. Project objectives included (1) determining the feasibility of the tri-partite collaborative concept; (2) designing, delivering, and evaluating psychological first aid (PFA) training and guided preparedness planning (GPP); and (3) documenting preliminary evidence of the sustainability and impact of the model. Methods We evaluated intervention effectiveness by analyzing pre- and post-training changes in participant responses on knowledge-acquisition tests administered to three urban and four rural community cohorts. Changes in percent of correct items and mean total correct items were evaluated. Criteria for model sustainability and impact were, respectively, observations of nonacademic partners engaging in efforts to advance post-project preparedness alliances, and project-attributable changes in preparedness-related practices of local or state governments. Results The majority (11 of 14) test items addressing technical or practical PFA content showed significant improvement; we observed comparable testing results for GPP training. Government and faith partners developed ideas and tools for sustaining preparedness activities, and numerous project-driven changes in local and state government policies were documented. Conclusions Results suggest that the model could be an effective approach to promoting public health preparedness and community resilience. PMID:25355980

  7. Mean-field thalamocortical modeling of longitudinal EEG acquired during intensive meditation training.

    PubMed

    Saggar, Manish; Zanesco, Anthony P; King, Brandon G; Bridwell, David A; MacLean, Katherine A; Aichele, Stephen R; Jacobs, Tonya L; Wallace, B Alan; Saron, Clifford D; Miikkulainen, Risto

    2015-07-01

    Meditation training has been shown to enhance attention and improve emotion regulation. However, the brain processes associated with such training are poorly understood and a computational modeling framework is lacking. Modeling approaches that can realistically simulate neurophysiological data while conforming to basic anatomical and physiological constraints can provide a unique opportunity to generate concrete and testable hypotheses about the mechanisms supporting complex cognitive tasks such as meditation. Here we applied the mean-field computational modeling approach using the scalp-recorded electroencephalogram (EEG) collected at three assessment points from meditating participants during two separate 3-month-long shamatha meditation retreats. We modeled cortical, corticothalamic, and intrathalamic interactions to generate a simulation of EEG signals recorded across the scalp. We also present two novel extensions to the mean-field approach that allow for: (a) non-parametric analysis of changes in model parameter values across all channels and assessments; and (b) examination of variation in modeled thalamic reticular nucleus (TRN) connectivity over the retreat period. After successfully fitting whole-brain EEG data across three assessment points within each retreat, two model parameters were found to replicably change across both meditation retreats. First, after training, we observed an increased temporal delay between modeled cortical and thalamic cells. This increase provides a putative neural mechanism for a previously observed reduction in individual alpha frequency in these same participants. Second, we found decreased inhibitory connection strength between the TRN and secondary relay nuclei (SRN) of the modeled thalamus after training. This reduction in inhibitory strength was found to be associated with increased dynamical stability of the model. Altogether, this paper presents the first computational approach, taking core aspects of physiology and

  8. Risk behavior-based model of the cubic growth of acquired immunodeficiency syndrome in the United States.

    PubMed Central

    Colgate, S A; Stanley, E A; Hyman, J M; Layne, S P; Qualls, C

    1989-01-01

    The cumulative number of cases of acquired immunodeficiency syndrome (AIDS) in the United States has grown as the cube of time rather than exponentially. We explain this by interactions involving partner choice and sexual frequency in a risk-behavior model with biased mixing. This leads to a saturation wave of infection moving from high- to low-risk groups. If this description is correct, then the decreasing growth rate of AIDS cases is not due to behavior changes; rather it is due to the intrinsic epidemiology of the disease. PMID:2543987

  9. Hurricane Preparedness and Control Plan

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This plan establishes policy and sets forth guidance, responsibilities and procedures utilized by Federal Electric Corp., communications department in support of the KSC Emergency Preparedness Plan, Annex A, Hurricane Control Plan (GP-355) dated 27 May 1971. This plan covers all FEC communications department personnel, facilities, and equipment situated at the Kennedy Space Center that are the responsibility of FEC contract NAS 10-4967.

  10. Health Informatics for Pediatric Disaster Preparedness Planning

    PubMed Central

    Burke, R.V.; Ryutov, T.; Neches, R.; Upperman, J.S.

    2010-01-01

    Objective 1. To conduct a review of the role of informatics in pediatric disaster preparedness using all medical databases. 2. To provide recommendations to improve pediatric disaster preparedness by the application of informatics. Methods A literature search was conducted using MEDLINE, CINHL and the Cochrane Library using the key words “children” AND “disaster preparedness and disaster” AND “informatics”. Results A total of 314 papers were initially produced by the search and eight that met the selection criteria were included in the review. Four themes emerged: tools for disaster preparedness, education, reunification and planning and response. Conclusion The literature pertaining to informatics and pediatric disaster preparedness is sparse and many gaps still persist. Current disaster preparedness tools focus on the general population and do not specifically address children. The most progress has been achieved in family reunification; however, the recommendations delineated are yet to be completed. PMID:23616840

  11. Modelling verbal aggression, physical aggression and inappropriate sexual behaviour after acquired brain injury

    PubMed Central

    James, Andrew I. W.; Böhnke, Jan R.; Young, Andrew W.; Lewis, Gary J.

    2015-01-01

    Understanding the underpinnings of behavioural disturbances following brain injury is of considerable importance, but little at present is known about the relationships between different types of behavioural disturbances. Here, we take a novel approach to this issue by using confirmatory factor analysis to elucidate the architecture of verbal aggression, physical aggression and inappropriate sexual behaviour using systematic records made across an eight-week observation period for a large sample (n = 301) of individuals with a range of brain injuries. This approach offers a powerful test of the architecture of these behavioural disturbances by testing the fit between observed behaviours and different theoretical models. We chose models that reflected alternative theoretical perspectives based on generalized disinhibition (Model 1), a difference between aggression and inappropriate sexual behaviour (Model 2), or on the idea that verbal aggression, physical aggression and inappropriate sexual behaviour reflect broadly distinct but correlated clinical phenomena (Model 3). Model 3 provided the best fit to the data indicating that these behaviours can be viewed as distinct, but with substantial overlap. These data are important both for developing models concerning the architecture of behaviour as well as for clinical management in individuals with brain injury. PMID:26136449

  12. The Effects of Exercise on Cognitive Recovery after Acquired Brain Injury in Animal Models: A Systematic Review

    PubMed Central

    Wogensen, Elise; Malá, Hana; Mogensen, Jesper

    2015-01-01

    The objective of the present paper is to review the current status of exercise as a tool to promote cognitive rehabilitation after acquired brain injury (ABI) in animal model-based research. Searches were conducted on the PubMed, Scopus, and psycINFO databases in February 2014. Search strings used were: exercise (and) animal model (or) rodent (or) rat (and) traumatic brain injury (or) cerebral ischemia (or) brain irradiation. Studies were selected if they were (1) in English, (2) used adult animals subjected to acquired brain injury, (3) used exercise as an intervention tool after inflicted injury, (4) used exercise paradigms demanding movement of all extremities, (5) had exercise intervention effects that could be distinguished from other potential intervention effects, and (6) contained at least one measure of cognitive and/or emotional function. Out of 2308 hits, 22 publications fulfilled the criteria. The studies were examined relative to cognitive effects associated with three themes: exercise type (forced or voluntary), timing of exercise (early or late), and dose-related factors (intensity, duration, etc.). The studies indicate that exercise in many cases can promote cognitive recovery after brain injury. However, the optimal parameters to ensure cognitive rehabilitation efficacy still elude us, due to considerable methodological variations between studies. PMID:26509085

  13. Emergency preparedness: addressing a residency training gap.

    PubMed

    Uddin, Sayeedha Ghori; Barnett, Daniel J; Parker, Cindy L; Links, Jonathan M; Alexander, Miriam

    2008-03-01

    As the importance of physician involvement and leadership in crisis preparedness is recognized, the literature suggests that few physicians are adequately trained to practice effectively in a large-scale crisis situation. A logical method for addressing the emergency preparedness training deficiency identified across several medical specialties is to include disaster and emergency preparedness training in residency curricula. In this article, the authors outline the development and implementation of an emergency preparedness curriculum for the Johns Hopkins General Preventive Medicine Residency (JHGPMR) from 2004 to 2006. The curriculum consists of two components. The first was developed for the academic year in the JHGPMR and includes didactic lectures, practical exercises to apply new knowledge, and an opportunity to integrate the knowledge and skills in a real-world exercise. The second, developed for the practicum year of the residency, includes Web-based lectures and online content and culminates in a tabletop preparedness exercise. Topics for both components include weapons of mass destruction, risk communication and personal preparedness, aspects of local emergency response planning, and mental health and psychological aspects of terrorism. On the basis of the emergency preparedness training gap that has been identified in the literature, and the success of the three-year experience in implementing a preparedness training curriculum in the JHGPMR, the authors recommend incorporation of competency-based emergency preparedness training for residencies of all specialties, and offer insights into how the described curriculum could be adapted for use in other residency settings. PMID:18316882

  14. Hospital Disaster Preparedness Tools: a Systematic Review

    PubMed Central

    Heidaranlu, Esmail; Ebadi, Abbas; Khankeh, Hamid Reza; Ardalan, Ali

    2015-01-01

    Aim: Evaluating hospital disaster preparedness is one the best ways for hospital accreditation. The aim of this study was to evaluate the quality of outcome measure that offer the level of measurement, reliability and validity that are known as the ‘ psychometric properties’ of the current hospital disaster preparedness tools. Methods: In total, 140 studies were retrieved. Studies which had been published from 2000 to 2014 and had used hospital disaster preparedness tools were appraised by using the PRISMA guideline. The content quality and the quality of the psychometric properties of the retrieved tools were assessed by using the World Health Organization Criteria for Hospital Preparedness as well as the COSMIN criteria. Findings: Only 33 studies met the inclusion criteria. In total, eleven hospital disaster preparedness tools had been used in these 33 studies. These tools mainly focused on evaluating structural and non-structural aspects of hospital preparedness and paid little attention, if any, to the key functional aspect. Conclusion: Given the paramount importance of evaluating hospital disaster preparedness and the weaknesses of current preparedness evaluation tools, valid and reliable tools should be developed by using experts’ knowledge and experience through the processes of tool development and psychometric evaluation. Keywords: Hospital preparedness, Measurement tool, Disaster, Systematic review PMID:26425401

  15. 76 FR 64960 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on November 1, 2011 in... INFORMATION: The role and functions of the Federal Radiological Preparedness Coordinating Committee...

  16. 77 FR 24213 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-23

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on May 3, 2012 in... role and functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC)...

  17. 75 FR 27563 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on June 3, 2010 in... the Federal Radiological Preparedness Coordinating Committee (FRPCC) are described in 44 CFR...

  18. 75 FR 56127 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee is holding a public meeting on September 28, 2010 in Arlington... . SUPPLEMENTARY INFORMATION: The role and functions of the Federal Radiological Preparedness...

  19. 77 FR 7597 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on February 24, 2012 in... . SUPPLEMENTARY INFORMATION: The role and functions of the Federal Radiological Preparedness...

  20. Bayesian framework for parametric bivariate accelerated lifetime modeling and its application to hospital acquired infections.

    PubMed

    Bilgili, D; Ryu, D; Ergönül, Ö; Ebrahimi, N

    2016-03-01

    Infectious diseases that can be spread directly or indirectly from one person to another are caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi. Infectious diseases remain one of the greatest threats to human health and the analysis of infectious disease data is among the most important application of statistics. In this article, we develop Bayesian methodology using parametric bivariate accelerated lifetime model to study dependency between the colonization and infection times for Acinetobacter baumannii bacteria which is leading cause of infection among the hospital infection agents. We also study their associations with covariates such as age, gender, apache score, antibiotics use 3 months before admission and invasive mechanical ventilation use. To account for singularity, we use Singular Bivariate Extreme Value distribution to model residuals in Bivariate Accelerated lifetime model under the fully Bayesian framework. We analyze a censored data related to the colonization and infection collected in five major hospitals in Turkey using our methodology. The data analysis done in this article is for illustration of our proposed method and can be applied to any situation that our model can be used. PMID:26394029

  1. A Cognitive Model of Acquiring Embodied Expertise Through Meta-cognitive Verbalization

    NASA Astrophysics Data System (ADS)

    Suwa, Masaki

    Based on the conjecture that acquisition of embodied expertise is a phenomenon that occurs through interactions among the learner's verbal thoughts, perception, physical movements and the surrounding environment, Suwa [2005b] has claimed the significance of dealing with subjective data such as verbalized thoughts in researches on embodied skills, and has advocated a theory on meta-cognitive verbalization. The present paper, based on the empirical findings in playing darts game, provides a cognitive model of embodied meta-cognitive verbalization. This model theorizes what kinds of cognitive processes involve embodied meta-cognitive verbalization, and how these processes change a learner's thoughts, perception, actions and self-awareness to those, and thereby promote acquisition of embodied expertise.

  2. The value of a UAV-acquired DEM for flood inundation mapping and modeling

    NASA Astrophysics Data System (ADS)

    Schumann, Guy J.-P.; Muhlhausen, Joseph; Andreadis, Konstantinos

    2016-04-01

    Remotely Piloted Systems also known as Unmanned Aerial Vehicle have rapidly developed as tools for remote sensing and mapping and publications referring to RPS remote sensing applications is increasing each year. In particular Structure from Motion (SfM), a relatively new photogrammetry approach has been documented for various applications. Some papers have focused on the accuracy of the output generated by SfM by validating relative and absolute accuracy using ground control points, others have looked at various applications. Yet we argue that a major aspect of SfM has been overlooked, its ability to generate highly accurate point cloud models without the use of ground control points. We demonstrate this by comparing with a LIDAR DEM, a dataset which has been transformative in flood inundation research and applications. Our results demonstrate that a point cloud collected using a RPS and a 16M pixel Bayer sensor camera using a rolling shutter can achieve a RMSE of 39 cm compared to LIDAR. We conclude that a SfM model is not only highly accurate but could complement LIDAR for floodplain mapping and modelling, especially in cases where smaller coverage is sufficient and LiDAR acquisition via airplane may be too costly or impractical.

  3. Stigma models: Testing hypotheses of how images of Nevada are acquired and values are attached to them

    SciTech Connect

    Jenkins-Smith, H.C.

    1994-12-01

    This report analyzes data from surveys on the effects that images associated with nuclear power and waste (i.e., nuclear images) have on people`s preference to vacation in Nevada. The analysis was stimulated by a model of imagery and stigma which assumes that information about a potentially hazardous facility generates signals that elicit negative images about the place in which it is located. Individuals give these images negative values (valences) that lessen their desire to vacation, relocate, or retire in that place. The model has been used to argue that the proposed Yucca Mountain high-level nuclear waste repository could elicit images of nuclear waste that would stigmatize Nevada and thus impose substantial economic losses there. This report proposes a revised model that assumes that the acquisition and valuation of images depend on individuals` ideological and cultural predispositions and that the ways in which new images will affect their preferences and behavior partly depend on these predispositions. The report tests these hypotheses: (1) individuals with distinct cultural and ideological predispositions have different propensities for acquiring nuclear images, (2) these people attach different valences to these images, (3) the variations in these valences are important, and (4) the valences of the different categories of images within an individual`s image sets for a place correlate very well. The analysis largely confirms these hypotheses, indicating that the stigma model should be revised to (1) consider the relevant ideological and cultural predispositions of the people who will potentially acquire and attach value to the image, (2) specify the kinds of images that previously attracted people to the host state, and (3) consider interactions between the old and potential new images of the place. 37 refs., 18 figs., 17 tabs.

  4. Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura.

    PubMed

    Deforche, Louis; Tersteeg, Claudia; Roose, Elien; Vandenbulcke, Aline; Vandeputte, Nele; Pareyn, Inge; De Cock, Elien; Rottensteiner, Hanspeter; Deckmyn, Hans; De Meyer, Simon F; Vanhoorelbeke, Karen

    2016-01-01

    Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy linked to a deficiency in the metalloprotease ADAMTS13. In the current study, a novel mouse model for acquired TTP was generated to facilitate development and validation of new therapies for this disease. Therefore, a large panel (n = 19) of novel anti-mouse ADAMTS13 (mADAMTS13) monoclonal antibodies (mAbs) of mouse origin was generated. Inhibitory anti-mADAMTS13 mAbs were identified using the FRETS-VWF73 assay. Four mAbs strongly inhibited mADAMTS13 activity in vitro (∼68-90% inhibition). Injecting a combination of 2 inhibitory mAbs (13B4 and 14H7, 1.25 mg/kg each) in Adamts13+/+ mice resulted in full inhibition of plasma ADAMTS13 activity (96 ± 4% inhibition, day 1 post injection), leading to the appearance of ultra-large von Willebrand factor (UL-VWF) multimers. Interestingly, the inhibitory anti-mADAMTS13 mAbs 13B4 and 14H7 were ideally suited to induce long-term ADAMTS13 deficiency in Adamts13+/+ mice. A single bolus injection resulted in full ex vivo inhibition for more than 7 days. As expected, the mice with the acquired ADAMTS13 deficiency did not spontaneously develop TTP, despite the accumulation of UL-VWF multimers. In line with the Adamts13-/- mice, TTP-like symptoms could only be induced when an additional trigger (rVWF) was administered. On the other hand, the availability of our panel of anti-mADAMTS13 mAbs allowed us to further develop a sensitive ELISA to detect ADAMTS13 in mouse plasma. In conclusion, a novel acquired TTP mouse model was generated through the development of inhibitory anti-mADAMTS13 mAbs. Consequently, this model provides new opportunities for the development and validation of novel treatments for patients with TTP. In addition, these newly developed inhibitory anti-mADAMTS13 mAbs are of great value to specifically study the role of ADAMTS13 in mouse models of thrombo-inflammatory disease. PMID:27479501

  5. Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura

    PubMed Central

    Deforche, Louis; Tersteeg, Claudia; Roose, Elien; Vandenbulcke, Aline; Vandeputte, Nele; Pareyn, Inge; De Cock, Elien; Rottensteiner, Hanspeter; Deckmyn, Hans; De Meyer, Simon F.; Vanhoorelbeke, Karen

    2016-01-01

    Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy linked to a deficiency in the metalloprotease ADAMTS13. In the current study, a novel mouse model for acquired TTP was generated to facilitate development and validation of new therapies for this disease. Therefore, a large panel (n = 19) of novel anti-mouse ADAMTS13 (mADAMTS13) monoclonal antibodies (mAbs) of mouse origin was generated. Inhibitory anti-mADAMTS13 mAbs were identified using the FRETS-VWF73 assay. Four mAbs strongly inhibited mADAMTS13 activity in vitro (∼68–90% inhibition). Injecting a combination of 2 inhibitory mAbs (13B4 and 14H7, 1.25 mg/kg each) in Adamts13+/+ mice resulted in full inhibition of plasma ADAMTS13 activity (96 ± 4% inhibition, day 1 post injection), leading to the appearance of ultra-large von Willebrand factor (UL-VWF) multimers. Interestingly, the inhibitory anti-mADAMTS13 mAbs 13B4 and 14H7 were ideally suited to induce long-term ADAMTS13 deficiency in Adamts13+/+ mice. A single bolus injection resulted in full ex vivo inhibition for more than 7 days. As expected, the mice with the acquired ADAMTS13 deficiency did not spontaneously develop TTP, despite the accumulation of UL-VWF multimers. In line with the Adamts13-/- mice, TTP-like symptoms could only be induced when an additional trigger (rVWF) was administered. On the other hand, the availability of our panel of anti-mADAMTS13 mAbs allowed us to further develop a sensitive ELISA to detect ADAMTS13 in mouse plasma. In conclusion, a novel acquired TTP mouse model was generated through the development of inhibitory anti-mADAMTS13 mAbs. Consequently, this model provides new opportunities for the development and validation of novel treatments for patients with TTP. In addition, these newly developed inhibitory anti-mADAMTS13 mAbs are of great value to specifically study the role of ADAMTS13 in mouse models of thrombo-inflammatory disease. PMID:27479501

  6. Derivation of a risk assessment model for hospital-acquired venous thrombosis: the NAVAL score.

    PubMed

    de Bastos, Marcos; Barreto, Sandhi M; Caiafa, Jackson S; Boguchi, Tânia; Silva, José Luiz Padilha; Rezende, Suely M

    2016-05-01

    Venous thrombosis (VT) is a preventable cause of death in hospitalized patients. The main strategy to decrease VT incidence is timely thromboprophylaxis in at-risk patients. We sought to evaluate the reliability of risk assessment model (RAM) data, the incremental usefulness of additional variables and the modelling of an adjusted score (the NAVAL score). We used the RAM proposed by Caprini for initial assessment. A 5 % systematic sample of data was independently reviewed for reliability. We evaluated the incremental usefulness of six variables for VT during the score modelling by logistic regression. We then assessed the NAVAL score for calibration, reclassification and discrimination performances. We observed 11,091 patients with 37 (0.3 %) VT events. Using the Caprini RAM, high-risk and moderate-risk patients were respectively associated with a 17.4 (95 % confidence interval [CI] 6.1-49.9) and 4.2 (95 % CI 1.6-11.0) increased VT risk compared with low-risk patients. Four independent variables were selected for the NAVAL score: "Age", "Admission clinic", "History of previous VT event" and "History of thrombophilia". The area under the receiver-operating-characteristic curve for the NAVAL score was 0.72 (95 % CI 0.63-0.81). The Net Reclassification Index (NRI) for the NAVAL score compared with the Caprini RAM was -0.1 (95 % CI -0.3 to 0.1; p = 0.28). We conclude that the NAVAL score is a simplified tool for the stratification of VT risk in hospitalized patients. With only four variables, it demonstrated good performance and discrimination, but requires external validation before clinical application. We also confirm that the Caprini RAM can effectively stratify VT risk in hospitalized patients in our population. PMID:26446587

  7. Assessment of intensive care unit‐acquired weakness in young and old mice: An E. coli septic peritonitis model

    PubMed Central

    Hoogland, Inge C.M.; Wieske, Luuk; Weber, Nina C.; Verhamme, Camiel; Schultz, Marcus J.; van Schaik, Ivo N.; Horn, Janneke

    2015-01-01

    ABSTRACT Introduction: There are few reports of in vivo muscle strength measurements in animal models of ICU‐acquired weakness (ICU‐AW). In this study we investigated whether the Escherichia coli (E. coli) septic peritonitis mouse model may serve as an ICU‐AW model using in vivo strength measurements and myosin/actin assays, and whether development of ICU‐AW is age‐dependent in this model. Methods: Young and old mice were injected intraperitoneally with E. coli and treated with ceftriaxone. Forelimb grip strength was measured at multiple time points, and the myosin/actin ratio in muscle was determined. Results: E. coli administration was not associated with grip strength decrease, neither in young nor in old mice. In old mice, the myosin/actin ratio was lower in E. coli mice at t = 48 h and higher at t = 72 h compared with controls. Conclusions: This E. coli septic peritonitis mouse model did not induce decreased grip strength. In its current form, it seems unsuitable as a model for ICU‐AW. Muscle Nerve 53: 127–133, 2016 PMID:26015329

  8. Cross-sectional survey of the disaster preparedness of nurses across the Asia-Pacific region.

    PubMed

    Usher, Kim; Mills, Jane; West, Caryn; Casella, Evan; Dorji, Passang; Guo, Aimin; Koy, Virya; Pego, George; Phanpaseuth, Souksavanh; Phouthavong, Olaphim; Sayami, Jamuna; Lak, Muy Seang; Sio, Alison; Ullah, Mohammad Mofiz; Sheng, Yu; Zang, Yuli; Buettner, Petra; Woods, Cindy

    2015-12-01

    Healthcare workers who have received disaster preparedness education are more likely to report a greater understanding of disaster preparedness. However, research indicates that current nursing curricula do not adequately prepare nurses to respond to disasters. This is the first study to assess Asia-Pacific nurses' perceptions about their level of disaster knowledge, skills, and preparedness. A cross-sectional survey was conducted with 757 hospital and community nurses in seven Asia-Pacific countries. Data were collected using the modified Disaster Preparedness Evaluation Tool. Participants were found to have overall low-to-moderate levels of disaster knowledge, skills and preparedness, wherein important gaps were identified. A majority of the variance in disaster preparedness scores was located at the level of the individual respondent, not linked to countries or institutions. Multilevel random effects modelling identified disaster experience and education as significant factors of positive perceptions of disaster knowledge, skills, and management. The first step toward disaster preparedness is to ensure frontline health workers are able to respond effectively to disaster events. The outcomes of this study have important policy and education implications. PMID:26245707

  9. The Earthquake Preparedness Task Force Report. Revised.

    ERIC Educational Resources Information Center

    Roybal-Allard, Lucille

    A report on Earthquake Preparedness presents California school districts with direction for complying with existing earthquake preparedness planning laws. It first contains two sets of recommendations. The first set requires state action and is presented to the Legislature for consideration. The second set consists of policy statements and…

  10. Rural Hospital Preparedness for Neonatal Resuscitation

    ERIC Educational Resources Information Center

    Jukkala, Angela; Henly, Susan J.; Lindeke, Linda

    2008-01-01

    Context: Neonatal resuscitation is a critical component of perinatal services in all settings. Purpose: To systematically describe preparedness of rural hospitals for neonatal resuscitation, and to determine whether delivery volume and level of perinatal care were associated with overall preparedness or its indicators. Methods: We developed the…

  11. 78 FR 54743 - National Preparedness Month, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... hundred and thirty- eighth. (Presidential Sig.) [FR Doc. 2013-21822 Filed 9-5-13; 8:45 am] Billing code... Documents#0;#0; ] Proclamation 9009 of August 30, 2013 National Preparedness Month, 2013 By the President of... communities' resilience. During National Preparedness Month, we refocus our efforts on readying ourselves,...

  12. 77 FR 55097 - National Preparedness Month, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... the two hundred and thirty-seventh. (Presidential Sig.) [FR Doc. 2012-22149 Filed 9-5-12; 11:15 am... Documents#0;#0; ] Proclamation 8854 of August 31, 2012 National Preparedness Month, 2012 By the President of..., emergencies and natural disasters have tested the fabric of our country. During National Preparedness...

  13. 76 FR 54917 - National Preparedness Month, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    .... (Presidential Sig.) [FR Doc. 2011-22768 Filed 9-1-11; 11:15 am] Billing code 3195-W1-P ... September 2, 2011 Part IV The President Proclamation 8700--National Preparedness Month, 2011 #0; #0; #0... Preparedness Month, 2011 By the President of the United States of America A Proclamation Whenever our...

  14. 75 FR 53563 - National Preparedness Month, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... Independence of the United States of America the two hundred and thirty-fifth. (Presidential Sig.) [FR Doc... Preparedness Month, 2010 By the President of the United States of America A Proclamation During National Preparedness Month, we stress the importance of strengthening the security and resiliency of our Nation...

  15. Promoting Regional Disaster Preparedness among Rural Hospitals

    ERIC Educational Resources Information Center

    Edwards, Janine C.; Kang, JungEun; Silenas, Rasa

    2008-01-01

    Context and Purpose: Rural communities face substantial risks of natural disasters but rural hospitals face multiple obstacles to preparedness. The objective was to create and implement a simple and effective training and planning exercise to assist individual rural hospitals to improve disaster preparedness, as well as to enhance regional…

  16. Rhode Island School Terrorist Attack Preparedness

    ERIC Educational Resources Information Center

    Dube, Michael W. M.

    2012-01-01

    This study examined the state of safety and terrorist attack preparedness in Rhode Island Schools as determined by Rhode Island school leader perceptions. The study is descriptive in nature as it gathers data to describe a particular event or situation. Using a researcher generated survey based on terrorist preparedness guidelines and suggestions…

  17. Undergraduate nursing students' preparedness to "go rural".

    PubMed

    Sedgwick, Monique G; Yonge, Olive

    2008-07-01

    This article reports on a theme emerging from a focused ethnography examining the professional socialization of undergraduate fourth year nursing students during a rural hospital preceptored clinical experience. Nursing students and preceptors geographically dispersed over a 640,000 square kilometer rural area participated in this study. Students report student preparedness for the rural hospital setting means to "know what you are getting into". Assisting nursing students to prepare for the rural hospital preceptorship facilitates a positive experience thus increasing the effectiveness of the preceptorship model of clinical teaching. Having a positive rural-based experience also has the potential for recruiting new staff. These preliminary findings suggest that student preparation for the rural hospital preceptorship includes cognitive and psychological preparation, as well as the acquisition of common advanced clinical skills. PMID:18031871

  18. Impact of emergency preparedness exercise on performance.

    PubMed

    Agboola, Foluso; McCarthy, Tara; Biddinger, Paul D

    2013-01-01

    The aim of this study was to investigate whether prior participation in preparedness exercises was predictive of better performance on objective measures of response. We conducted a statewide tabletop exercise that focused on a hazardous materials (HAZMAT) scenario and assessed performance using our developed evaluation tool. The evaluative score was analyzed in relation to the number of HAZMAT exercises in the past 3 years, participation in prior CHEMPACK-specific exercise, hospital size, teaching status of the hospital, preparedness training experience, and participants years of experience in preparedness activities. Hospitals that had participated in more exercises in the past 3 years performed significantly better than hospitals that had participated in fewer exercises. No significant differences were found between the performance of hospitals in relation to size, teaching status, preparedness training experience, and participants' years of experience in preparedness activities. Our results suggest that more frequent participation in exercises may result in improved overall response. PMID:23903400

  19. Tsunami Preparedness in California (videos)

    USGS Publications Warehouse

    Filmed and edited by: Loeffler, Kurt; Gesell, Justine

    2010-01-01

    Tsunamis are a constant threat to the coasts of our world. Although tsunamis are infrequent along the West coast of the United States, it is possible and necessary to prepare for potential tsunami hazards to minimize loss of life and property. Community awareness programs are important, as they strive to create an informed society by providing education and training. These videos about tsunami preparedness in California distinguish between a local tsunami and a distant event and focus on the specific needs of each region. They offer guidelines for correct tsunami response and community preparedness from local emergency managers, first-responders, and leading experts on tsunami hazards and warnings, who have been working on ways of making the tsunami affected regions safer for the people and communities on a long-term basis. These videos were produced by the U.S. Geological Survey (USGS) in cooperation with the California Emergency Management Agency (CalEMA) and Pacific Gas and Electric Company (PG&E).

  20. Pre-Clinical Models of Acquired Neonatal Seizures: Differential Effects of Injury on Function of Chloride Co-Transporters

    PubMed Central

    Kang, SK; Kadam, SD

    2014-01-01

    Hypoxic-ischemic encephalopathy [HIE] represents the most common acquired pathology associated with neonatal seizures. HIE-associated neonatal seizures are often difficult to control, due to their refractoriness to traditional anti-seizure agents. Developmentally regulated chloride gradients during early development make the neonatal brain more seizure-susceptible by depolarizing GABAAR-mediated currents, and therefore hindering inhibition by conventional anti-seizure drugs such as phenobarbital [PB] and benzodiazepines. Pharmaco-modulation of chloride co-transporters has become a current field of research in treating refractory neonatal seizures, and the basis of two clinical trials [NCT01434225; NCT00380531]. However, the recent termination of NEMO study [NCT01434225] on bumetanide, an NKCC1 antagonist, suggests that clinical utilization of bumetanide as an adjunct to treat neonatal seizures with PB may not be a viable option. Hence, re-evaluation of bumetanide as an adjunct through pre-clinical studies is warranted. Additionally, the model-specific variability in the efficacy of bumetanide in the pre-clinical models of neonatal seizures highlights the differential consequences of insults used to induce seizures in each pre-clinical model as worth exploration. Injury itself can significantly alter the function of chloride co-transporters, and therefore the efficacy of anti-seizure agents that follow. PMID:25590049

  1. States at Risk: America's Preparedness Report Card

    NASA Astrophysics Data System (ADS)

    Yu, R. M. S.; Strauss, B.; Kulp, S. A.; Bronzan, J.; Rodehorst, B.; Bhat, C.; Dix, B.; Savonis, M.; Wiles, R.

    2015-12-01

    Many states are already experiencing the costly impacts of extreme climate and weather events. The occurrence, frequency and intensity of these events may change under future climates. Preparing for these changes takes time, and state government agencies and communities need to recognize the risks they could potentially face and the response actions already undertaken. The States at Risk: America's Preparedness Report Card project is the first-ever study that quantifies five climate-change-driven hazards, and the relevant state government response actions in each of the 50 states. The changing characteristics of extreme heat, drought, wildfires, inland and coastal flooding were assessed for the baseline period (around year 2000) through the years 2030 and 2050 across all 50 states. Bias-corrected statistically-downscaled (BCSD) climate projections (Reclamation, 2013) and hydrology projections (Reclamation, 2014) from the Coupled Model Intercomparison Project phase 5 (CMIP5) under RCP8.5 were used. The climate change response action analysis covers five critical sectors: Transportation, Energy, Water, Human Health and Communities. It examined whether there is evidence that the state is taking action to (1) reduce current risks, (2) raise its awareness of future risks, (3) plan for adaptation to the future risks, and (4) implement specific actions to reduce future risks for each applicable hazards. Results from the two analyses were aggregated and translated into a rating system that standardizes assessments across states, which can be easily understood by both technical and non-technical audiences. The findings in this study not only serve as a screening tool for states to recognize the hazards they could potentially face as climate changes, but also serve as a roadmap for states to address the gaps in response actions, and to improve climate preparedness and resilience.

  2. Citizen preparedness for disasters: are current assumptions valid?

    PubMed

    Uscher-Pines, Lori; Chandra, Anita; Acosta, Joie; Kellermann, Arthur

    2012-06-01

    US government programs and communications regarding citizen preparedness for disasters rest on several untested, and therefore unverified, assumptions. We explore the assumptions related to citizen preparedness promotion and argue that in spite of extensive messaging about the importance of citizen preparedness and countless household surveys purporting to track the preparedness activities of individuals and households, the role individual Americans are being asked to play is largely based on conventional wisdom. Recommendations for conceptualizing and measuring citizen preparedness are discussed. PMID:22700027

  3. Nuclear plant emergency preparedness in Russia.

    PubMed

    Sullivan, Randolph L

    2009-11-01

    An international team of experts conducted a detailed operational review at the Volgodonsk nuclear power plant. The review was the first mission by an International Atomic Energy Agency Operational Safety Review Team to Russia in over a decade. The author reviewed the emergency preparedness program in detail. Emergency preparedness professionals in the West are largely unfamiliar with Russian nuclear plant emergency preparedness programs, and the legacy of Chernobyl may leave some doubt as to their efficacy. This article describes the program in some detail and compares some elements to programs in the United States. The author was favorably impressed with the state of nuclear plant emergency preparedness in the Russian Federation and identified program elements that should be considered for implementation elsewhere. PMID:19820472

  4. Nursing leadership in disaster preparedness and response.

    PubMed

    Knebel, Ann R; Toomey, Lauren; Libby, Mark

    2012-01-01

    Nurses serve as leaders in disaster preparedness and response at multiple levels: within their own homes and neighborhoods, at disaster scenes, and the workplace, which can vary from a health care facility, in the community, or at the state, national, or international level. This chapter provides an overview on theories of leadership with a historical context for nursing leadership; setting the context for nursing leadership in disaster preparedness and response. Although few research studies exist, there are numerous examples of nurses who provide leadership for disaster preparedness and response. To define the current state of the science, the research studies cited in this chapter are supplemented with case studies from particular disasters. The major finding of this review is that nursing leadership in disaster preparedness and response is a field of study that needs to be developed. PMID:24894051

  5. Revised Phylogeny and Novel Horizontally Acquired Virulence Determinants of the Model Soft Rot Phytopathogen Pectobacterium wasabiae SCC3193

    PubMed Central

    Koskinen, Patrik; Nokso-Koivisto, Jussi; Pasanen, Miia; Broberg, Martin; Plyusnin, Ilja; Törönen, Petri; Holm, Liisa; Pirhonen, Minna; Palva, E. Tapio

    2012-01-01

    Soft rot disease is economically one of the most devastating bacterial diseases affecting plants worldwide. In this study, we present novel insights into the phylogeny and virulence of the soft rot model Pectobacterium sp. SCC3193, which was isolated from a diseased potato stem in Finland in the early 1980s. Genomic approaches, including proteome and genome comparisons of all sequenced soft rot bacteria, revealed that SCC3193, previously included in the species Pectobacterium carotovorum, can now be more accurately classified as Pectobacterium wasabiae. Together with the recently revised phylogeny of a few P. carotovorum strains and an increasing number of studies on P. wasabiae, our work indicates that P. wasabiae has been unnoticed but present in potato fields worldwide. A combination of genomic approaches and in planta experiments identified features that separate SCC3193 and other P. wasabiae strains from the rest of soft rot bacteria, such as the absence of a type III secretion system that contributes to virulence of other soft rot species. Experimentally established virulence determinants include the putative transcriptional regulator SirB, two partially redundant type VI secretion systems and two horizontally acquired clusters (Vic1 and Vic2), which contain predicted virulence genes. Genome comparison also revealed other interesting traits that may be related to life in planta or other specific environmental conditions. These traits include a predicted benzoic acid/salicylic acid carboxyl methyltransferase of eukaryotic origin. The novelties found in this work indicate that soft rot bacteria have a reservoir of unknown traits that may be utilized in the poorly understood latent stage in planta. The genomic approaches and the comparison of the model strain SCC3193 to other sequenced Pectobacterium strains, including the type strain of P. wasabiae, provides a solid basis for further investigation of the virulence, distribution and phylogeny of soft rot

  6. Revised phylogeny and novel horizontally acquired virulence determinants of the model soft rot phytopathogen Pectobacterium wasabiae SCC3193.

    PubMed

    Nykyri, Johanna; Niemi, Outi; Koskinen, Patrik; Nokso-Koivisto, Jussi; Pasanen, Miia; Broberg, Martin; Plyusnin, Ilja; Törönen, Petri; Holm, Liisa; Pirhonen, Minna; Palva, E Tapio

    2012-01-01

    Soft rot disease is economically one of the most devastating bacterial diseases affecting plants worldwide. In this study, we present novel insights into the phylogeny and virulence of the soft rot model Pectobacterium sp. SCC3193, which was isolated from a diseased potato stem in Finland in the early 1980s. Genomic approaches, including proteome and genome comparisons of all sequenced soft rot bacteria, revealed that SCC3193, previously included in the species Pectobacterium carotovorum, can now be more accurately classified as Pectobacterium wasabiae. Together with the recently revised phylogeny of a few P. carotovorum strains and an increasing number of studies on P. wasabiae, our work indicates that P. wasabiae has been unnoticed but present in potato fields worldwide. A combination of genomic approaches and in planta experiments identified features that separate SCC3193 and other P. wasabiae strains from the rest of soft rot bacteria, such as the absence of a type III secretion system that contributes to virulence of other soft rot species. Experimentally established virulence determinants include the putative transcriptional regulator SirB, two partially redundant type VI secretion systems and two horizontally acquired clusters (Vic1 and Vic2), which contain predicted virulence genes. Genome comparison also revealed other interesting traits that may be related to life in planta or other specific environmental conditions. These traits include a predicted benzoic acid/salicylic acid carboxyl methyltransferase of eukaryotic origin. The novelties found in this work indicate that soft rot bacteria have a reservoir of unknown traits that may be utilized in the poorly understood latent stage in planta. The genomic approaches and the comparison of the model strain SCC3193 to other sequenced Pectobacterium strains, including the type strain of P. wasabiae, provides a solid basis for further investigation of the virulence, distribution and phylogeny of soft rot

  7. The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis.

    PubMed

    Gintant, G A; Limberis, J T; McDermott, J S; Wegner, C D; Cox, B F

    2001-05-01

    Torsade de pointes is a rare but potentially fatal ventricular arrhythmia associated with drug-induced delayed repolarization and prolongation of the QT interval. To determine if the arrhythmogenic potential of noncardiac drugs can be assessed in vitro, we evaluated the effects of 12 drugs on the action potential duration (APD) of cardiac Purkinje fibers and compared results with clinical observations. APD changes in canine and porcine fibers were evaluated under physiologic conditions (37 degrees C, [K+]0 = 4 mM) using standard microelectrode techniques. Six of seven drugs associated with QT prolongation or torsade de pointes in man (cisapride, erythromycin, grepafloxacin, moxifloxacin, sertindole, and sotalol) affected concentration-dependent prolongation of the APD in canine fibers during slow stimulation (2-s basic cycle length), attaining greater than 15% prolongation at high concentrations (> or = 10-fold clinically encountered plasma levels). Each of five drugs not linked clinically to QT prolongation and torsade de pointes (azithromycin, enalaprilat, fluoxetine, indomethacin, and pinacidil) failed to attain 15% prolongation, with fluoxetine, indomethacin, and pinacidil abbreviating the APD. Drugs eliciting the greatest prolongation also demonstrated prominent reverse rate-dependent effects. The antihistamine terfenadine (linked to dose-dependent QT prolongation and torsade de pointes clinically) only minimally prolonged the APD in canine and porcine fibers (and exerted no effect on midmyocardial fibers from left ventricular free wall) at supratherapeutic concentrations. On the basis of concentration-dependent APD prolongation and reverse rate-dependent effects, this Purkinje fiber model detects six of seven drugs linked clinically to acquired long QT syndrome and torsade de pointes, and clears each of five drugs not associated with repolarization abnormalities (overall 92% accuracy), validating the utility of this Purkinje fiber model in the preclinical

  8. Preparedness and response to bioterrorism.

    PubMed

    Spencer, R C; Lightfoot, N F

    2001-08-01

    As we enter the 21st century the threats of biological warfare and bioterrorism (so called asymmetric threats) appear to be more real than ever before. Historical evidence suggests that biological weapons have been used, with varying degrees of success, for many centuries. Despite the international agreements to ban such weapons, namely the 1925 Geneva Protocol and the 1975 Biological and Toxin Weapons Convention, there is no effective international mechanism for challenging either the development of biological weapons or their use. Advances in technology and the rise of fundamentalist terror groups combine to present a significant threat to western democracies. A timely and definitive response to this threat will require co-operation between governments on a scale never seen before. There is a need for proper planning, good communication between various health, home office, defence and intelligence agencies and sufficient financial support for a realistic state of preparedness. The Department of Health has produced guidelines for responding to real or suspected incidents and the Public Health Laboratory Service (PHLS) has produced detailed protocols to inform the actions required by microbiologists and consultants in communicable disease control. These protocols will be published on the Department of Health and PHLS web sites. PMID:11676515

  9. Conceptualizing and measuring community preparedness within public health preparedness and response: complexities and lessons learned.

    PubMed

    Kun, Karen E; Rose, Dale A; Morris, Thomas; Salter, Monique; Lamia, Tamara; Bhalakia, Amee; McLees, Anita W

    2014-01-01

    Since 2001, the Centers for Disease Control and Prevention's Public Health Emergency Preparedness cooperative agreement has supported state, territorial, and local public health departments in preparing for and responding to public health emergencies. This conceptual article describes complexities identified and lessons learned in developing community preparedness performance measures for the Centers for Disease Control and Prevention's public health preparedness program. Challenges arose in (a) defining community; (b) measuring meaningful community engagement; and (c) determining a strategy for collecting, aggregating, and analyzing data from diverse state, territorial, and local health departments. This article contributes to prior work describing conceptual challenges in developing standardized measures of performance at the federal level and suggests ways to potentially mitigate general performance measurement challenges as well as measurement complexities specific to community preparedness. It may be informative for those state, territorial, and local health departments currently implementing (or contemplating implementing) community preparedness activities and for individuals more generally engaged in performance measurement. PMID:24322842

  10. (Geo)Ethics. Step 1: Preparedness.

    NASA Astrophysics Data System (ADS)

    Marone, Eduardo

    2015-04-01

    Natural hazards have been defined in several ways in recent decades. Whatever your choice, it will be fine provided you consider that they are complex physical phenomena that expose a natural area to risk of loss of life, environmental degradation and property damages. In a time-line, one may divide the hazards, particularly those considered extremes, in a pre-event phase, the event itself and a post-event period. At this moment, I would like to promote an initial reflection by focusing in the geoethical behaviour scientists have to bear in mind accordingly to the particular characteristics of the pre-event phase, considering ethics as a way of systematizing, defending and recommending concepts of right and wrong conduct. In an accelerated world, where the pressure of the every day life gives us little room to exercise our mind to think in such apparent démodé issues as ethics, society, nature, responsibilities and duties, I would like to invite you to stop few minutes and reflect on the ethical implications of being a geoscientists dealing with natural hazards in the XXI century. The most dangerous hazards are those extreme events with a rapid onset (earthquakes, tsunamis, etc.). Thus far, science has not found effective ways to predict and reduce most natural hazards. If we are not capable to forecast or minimize the effect of an extreme event, geosciences, and scientists, are responsible of in deep risk assessments for areas that might be subject to natural hazards also contributing to preparedness of society. However, we have been working on that issues, but it seems we are not being as efficient as needed. On the risk analysis, which includes forecast models, we use to be too Cartesians, taking too much time in arriving to conclusions when a non clear cause-effect chain can be identified. It is our ethical duty to evaluate when to stop searching for causes when dealing with complex systems. The search for a specific cause for a given extreme natural event

  11. Direct pharmacological assessment of clinically acquired models as a strategy to overcome resistance to tyrosine kinase inhibitors

    PubMed Central

    Benes, Cyril H

    2015-01-01

    We have performed a study using cell lines established from biopsies of clinically resistant non-small cell lung cancers with the aim of discovering therapeutic strategies to overcome acquired resistance. Our results indicate that pharmacological assessment of tumor material might efficiently complement genetic profiling in the future path toward personalized medicine. PMID:27308520

  12. Direct pharmacological assessment of clinically acquired models as a strategy to overcome resistance to tyrosine kinase inhibitors.

    PubMed

    Benes, Cyril H

    2015-01-01

    We have performed a study using cell lines established from biopsies of clinically resistant non-small cell lung cancers with the aim of discovering therapeutic strategies to overcome acquired resistance. Our results indicate that pharmacological assessment of tumor material might efficiently complement genetic profiling in the future path toward personalized medicine. PMID:27308520

  13. Community preparedness for emergency: a cross-sectional survey of residents in Heilongjiang of China

    PubMed Central

    Xu, Weilan; Hao, Yanhua; Wu, Qunhong; Ning, Ning; You, Jia; Liu, Chaojie; Jiao, Mingli; Gao, Lijun; Kang, Zheng; Liang, Libo; Sun, Hong; Cui, Yu; Li, Ye; Han, Xiaonan; Fang, Xin; Zhao, Xiyan; Hu, Man; Ding, Ding; Gao, Hao; Lu, Jun

    2015-01-01

    Objective This article aims to identify factors that shape the knowledge, attitudes and behaviours of community residents in China's Heilongjiang province towards emergency preparedness. Findings of such a study may provide evidence to support the development of effective public risk communication strategies and education campaigns. Design A cross-sectional household questionnaire survey was conducted in Heilongjiang province in 2014. A stratified cluster sampling strategy was employed to select study participants. The questionnaires were administered using face-to-face interviews. 2800 questionnaires were completed, among which 2686 (95.9%) were considered valid for data analyses. A multivariate logistic regression model was adopted to identify the extent to which the independent variables were associated with emergency preparedness. Results Fewer than 5% respondents were well prepared for emergency. Over half (52%) of poorly prepared respondents did not know what to do in emergency; women (OR=1.691), higher household income (OR ranging from 1.666 to 2.117), previous experience with emergency (OR=1.552), higher levels of knowledge about emergency (OR=2.192), risk awareness (OR=1.531), self-efficacy (OR=1.796), as well as positive attitudes towards emergency preparedness (OR=2.265) were significant predictors for emergency preparedness. Neither educational attainment nor exposure to awareness-raising entered into the logic regression model as a significant predictor for emergency preparedness. Conclusions The level of emergency preparedness in Heilongjiang residents is very low, which is linked with poor knowledge and attitudes of the residents towards emergency preparedness. Future emergency awareness campaigns should be more focused and tailored to the needs of intended audience, taking into consideration of their usual source of information and knowledge in relation to emergency. PMID:26553829

  14. 75 FR 67807 - Pipeline Safety: Emergency Preparedness Communications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Communications AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA); DOT. ACTION: Notice... Hazardous Liquid and Gas Pipeline Systems. Subject: Emergency Preparedness Communications. Advisory: To... preparedness communications between pipeline operators and emergency responders. To ensure a prompt,...

  15. 76 FR 2131 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on January 20, 2011 in....greten@dhs.gov . SUPPLEMENTARY INFORMATION: The role and functions of the Federal...

  16. 77 FR 64562 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Draft Emergency Preparedness Frequently Asked Questions AGENCY: Nuclear Regulatory Commission... Commission (NRC) is making available for comment Emergency Preparedness (EP) frequently asked...

  17. 78 FR 52570 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Draft Emergency Preparedness Frequently Asked Questions AGENCY: Nuclear Regulatory Commission... Commission (NRC) is making available for comment Emergency Preparedness (EP) frequently asked...

  18. 78 FR 33862 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Draft Emergency Preparedness Frequently Asked Questions AGENCY: Nuclear Regulatory Commission... Commission (NRC) is making available for comment Emergency Preparedness (EP) frequently asked...

  19. Preparedness for Death and Adjustment to Bereavement among Caregivers of Recently Placed Nursing Home Residents

    PubMed Central

    Boerner, Kathrin; Klinger, Julie; Rosen, Jules

    2015-01-01

    Abstract Background: Preparedness for death as a predictor of post-bereavement adjustment has not been studied prospectively. Little is known about pre-death factors associated with feeling prepared prior to the death of a loved one. Objective: Our aim was to prospectively assess the role of preparedness for death as a predictor of post-bereavement adjustment in informal caregivers (CGs) who experienced the death of their loved one and to identify predictors and correlates of complicated grief, depression, and preparedness for death among informal CGs. Methods: We conducted a prospective, longitudinal study using data collected for a randomized trial testing the efficacy of an intervention for CGs of recently placed care recipients (CRs). Subjects were 217 informal CGs of care recipients recently placed in nursing homes, and they were followed for 18 months. CGs were assessed in person by certified interviewers at 6-month intervals. Eighty-nine CGs experienced the death of their loved one in the course of the study. Measurements used included preparedness for death, advance care planning (ACP), complicated grief, depression, and sociodemographic characteristics. Results: CGs who reported feeling more prepared for the death experienced lower levels of complicated grief post-bereavement. A multivariate ordinal logistic regression model showed that spouses as opposed to adult child CGs were less prepared for the death, depressed CGs were less prepared, and patients who engaged in ACP had CGs who felt more prepared. CR overt expressions about wanting to die was also related to higher levels of preparedness in the CG. Conclusions: We show prospectively that preparedness for death facilitates post-bereavement adjustment and identify factors associated with preparedness. ACP can be an effective means for preparing informal CGs for the death of their CRs. PMID:25469737

  20. The anatomical foundations of acquired reading disorders: a neuropsychological verification of the dual-route model of reading.

    PubMed

    Ripamonti, E; Aggujaro, S; Molteni, F; Zonca, G; Frustaci, M; Luzzatti, C

    2014-07-01

    In this study we investigated the neural correlates of acquired reading disorders through an anatomo-correlative procedure of the lesions of 59 focal brain damaged patients suffering from acquired surface, phonological, deep, undifferentiated dyslexia and pure alexia. Two reading tasks, one of words and nonwords and one of words with unpredictable stress position, were used for this study. We found that surface dyslexia was predominantly associated with left temporal lesions, while in phonological dyslexia the lesions overlapped in the left insula and the left inferior frontal gyrus (pars opercularis) and that pure alexia was associated with lesions in the left fusiform gyrus. A number of areas and white matter tracts, which seemed to involve processing along both the lexical and the sublexical routes, were identified for undifferentiated dyslexia. Two cases of deep dyslexia with relatively dissimilar anatomical correlates were studied, one compatible with Coltheart's right-hemisphere hypothesis (1980) whereas the other could be interpreted in the context of Morton and Patterson's (1980), multiply-damaged left-hemisphere hypothesis. In brief, the results of this study are only partially consistent with the current state of the art, and propose new and stimulating challenges; indeed, based on these results we suggest that different types of acquired dyslexia may ensue after different cortical damage, but white matter disconnection may play a crucial role in some cases. PMID:24815949

  1. Emotions, trust, and perceived risk: affective and cognitive routes to flood preparedness behavior.

    PubMed

    Terpstra, Teun

    2011-10-01

    Despite the prognoses of the effects of global warming (e.g., rising sea levels, increasing river discharges), few international studies have addressed how flood preparedness should be stimulated among private citizens. This article aims to predict Dutch citizens' flood preparedness intentions by testing a path model, including previous flood hazard experiences, trust in public flood protection, and flood risk perceptions (both affective and cognitive components). Data were collected through questionnaire surveys in two coastal communities (n= 169, n= 244) and in one river area community (n= 658). Causal relations were tested by means of structural equation modeling (SEM). Overall, the results indicate that both cognitive and affective mechanisms influence citizens' preparedness intentions. First, a higher level of trust reduces citizens' perceptions of flood likelihood, which in turn hampers their flood preparedness intentions (cognitive route). Second, trust also lessens the amount of dread evoked by flood risk, which in turn impedes flood preparedness intentions (affective route). Moreover, the affective route showed that levels of dread were especially influenced by citizens' negative and positive emotions related to their previous flood hazard experiences. Negative emotions most often reflected fear and powerlessness, while positive emotions most frequently reflected feelings of solidarity. The results are consistent with the affect heuristic and the historical context of Dutch flood risk management. The great challenge for flood risk management is the accommodation of both cognitive and affective mechanisms in risk communications, especially when most people lack an emotional basis stemming from previous flood hazard events. PMID:21477090

  2. Reducing losses from earthquakes through personal preparedness

    USGS Publications Warehouse

    Kockelman, W.J.

    1985-01-01

    A prerequisite to personal preparedness is familiarity with and concern about the other hazard-reduction phases. Strengthening the structure of the home, storing water, and showing family members how to shut off utility-supply lines are only a part of personal preparedness. Equally important are other phases such as picking up children from an evacuated school, securing heavy objects at the work palce as well as in the home, and retrofitting the commuter-highway overpasses needed to reunite a family. 

  3. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Industrial preparedness... ACQUISITION REGULATIONS SOLICITATIONS PROVISIONS AND CONTRACT CLAUSES 5152.208-9001 Industrial preparedness... contractor is designated a Limited Fee Planned Producer. Industrial Preparedness Planning (XXX 1989) (DEV)...

  4. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Industrial preparedness... ACQUISITION REGULATIONS SOLICITATIONS PROVISIONS AND CONTRACT CLAUSES 5152.208-9001 Industrial preparedness... contractor is designated a Limited Fee Planned Producer. Industrial Preparedness Planning (XXX 1989) (DEV)...

  5. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Industrial preparedness... ACQUISITION REGULATIONS SOLICITATIONS PROVISIONS AND CONTRACT CLAUSES 5152.208-9001 Industrial preparedness... contractor is designated a Limited Fee Planned Producer. Industrial Preparedness Planning (XXX 1989) (DEV)...

  6. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Industrial preparedness... ACQUISITION REGULATIONS SOLICITATIONS PROVISIONS AND CONTRACT CLAUSES 5152.208-9001 Industrial preparedness... contractor is designated a Limited Fee Planned Producer. Industrial Preparedness Planning (XXX 1989) (DEV)...

  7. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Industrial preparedness... ACQUISITION REGULATIONS SOLICITATIONS PROVISIONS AND CONTRACT CLAUSES 5152.208-9001 Industrial preparedness... contractor is designated a Limited Fee Planned Producer. Industrial Preparedness Planning (XXX 1989) (DEV)...

  8. 76 FR 35902 - Federal Radiological Preparedness Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... SECURITY Federal Emergency Management Agency Federal Radiological Preparedness Coordinating Committee... Radiological Preparedness Coordinating Committee (FRPCC) is holding a public meeting on July 11, 2011 in... Radiological Preparedness Coordinating Committee (FRPCC) are described in 44 CFR parts 351.10(a) and...

  9. 49 CFR 239.101 - Emergency preparedness plan.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Emergency preparedness plan. 239.101 Section 239.101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PASSENGER TRAIN EMERGENCY PREPAREDNESS Specific Requirements § 239.101 Emergency preparedness plan. (a)...

  10. 49 CFR 239.101 - Emergency preparedness plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Emergency preparedness plan. 239.101 Section 239.101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PASSENGER TRAIN EMERGENCY PREPAREDNESS Specific Requirements § 239.101 Emergency preparedness plan. (a)...

  11. Enhancing the Relevance of Incident Management Systems in Public Health Emergency Preparedness: A Novel Conceptual Framework.

    PubMed

    Bochenek, Richard; Grant, Moira; Schwartz, Brian

    2015-08-01

    We outline a conceptual framework developed to meet the needs of public health professionals in the province of Ontario for incident management system-related education and training. By using visual models, this framework applies a public health lens to emergency management, introducing concepts relevant to public health and thereby shifting the focus of emergency preparedness from a strict "doctrine" to a more dynamic and flexible approach grounded in the traditional principles of incident management systems. These models provide a foundation for further exploration of the theoretical foundations for public health emergency preparedness in practice. PMID:25991506

  12. Hospital-acquired pneumonia

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/000146.htm Hospital-acquired pneumonia To use the sharing features on this page, please enable JavaScript. Hospital-acquired pneumonia is an infection of the lungs ...

  13. Teaching Disaster Preparedness to Rural Communities in El Salvador.

    NASA Astrophysics Data System (ADS)

    Barton, T.

    2014-12-01

    Natural disasters are becoming more common around the world, and it is widely accepted that developing nations show the highest rates of vulnerability. It makes sense to focus preparedness and mitigation efforts in these countries. However, it is important to realize that different teaching styles are required for different cultures with varying education systems and classroom atmospheres. The pedagogical models we use in the US can't be directly exported. A realistic assessment of the situation seen during two years living and working in rural El Salvador is presented, along with methods used and lessons learned.

  14. Tuberculosis control: lessons for outbreak preparedness in correctional facilities.

    PubMed

    Parvez, Farah M; Lobato, Mark N; Greifinger, Robert B

    2010-07-01

    Correctional facilities typically house large numbers of persons in close and crowded conditions for long periods. Clusters of communicable diseases ranging from simple viral upper respiratory infections to more serious threats, such as tuberculosis (TB), infections with methicillin-resistant Staphylococcus aureus, and influenza, often emerge in these surroundings. The recent H1N1 influenza pandemic highlights the importance of outbreak prevention and containment preparedness, particularly in congregate settings. In this commentary, the authors propose that the TB control model can provide valuable lessons for infection control practitioners to prepare for, identify, investigate, and control outbreaks of communicable diseases to prevent transmission in correctional facilities and to the surrounding community. PMID:20466700

  15. Assessing public health emergency preparedness: concepts, tools, and challenges.

    PubMed

    Nelson, Christopher; Lurie, Nicole; Wasserman, Jeffrey

    2007-01-01

    Policymakers are increasingly seeking to determine whether the federal government's recent investments in public health preparedness have left the public health system better prepared to respond to large-scale public health emergencies. Yet, there remain questions about how to define "public health emergency preparedness," how much preparedness is enough, and how preparedness can be measured and assessed. This chapter identifies the key challenges associated with measuring public health preparedness and reviews approaches currently in use. We also identify some emerging measurement techniques that might help address some of these challenges. PMID:17129174

  16. Emergency Preparedness: Balancing Electrical Supply and Demand

    ERIC Educational Resources Information Center

    Rose, Mary Annette

    2006-01-01

    Integrating technology learning goals and activities with recent experiences created by natural disasters is a valuable motivational strategy. The newfound appreciation that exists for personal emergency preparedness generates unique and sustained interest in alternative energy technologies and conservation. As described in this article, an ice…

  17. Examining Preservice Teachers' Preparedness for Teaching Art

    ERIC Educational Resources Information Center

    Hudson, Peter; Hudson, Sue

    2007-01-01

    The Australian Federal Government's call for another teacher education inquiry aims to investigate preservice teacher preparedness for teaching. Art education was selected for this study as the teaching of art education in primary schools occurs in less than ideal conditions and may often be avoided by generalist primary teachers (Russell-Bowie,…

  18. Emergency Health Preparedness: Expectations for Teachers.

    ERIC Educational Resources Information Center

    Winkelman, Jack L.

    Specific issues relevant to the emergency health preparedness of schools and the key roles and expectations applicable to teachers are outlined. It is noted that, while issues of legal liability relevant to teachers are complex, teachers are expected to: (1) anticipate possible risk or harm involved in activities; (2) give adequate warning of…

  19. Disaster Preparedness: Guidelines for School Nurses

    ERIC Educational Resources Information Center

    Doyle, Janice; Loyacono, Thomas R.

    2007-01-01

    These guidelines help school nurses understand their role in preparing for disasters and major emergencies. The guidelines are suitable for planning for a variety of emergency and disaster situations. Disaster Preparedness Guidelines for School Nurses is based on the four phases of disaster management as defined by the Federal Emergency Management…

  20. MBA Students' Preparedness for Enterpreneurial Efforts

    ERIC Educational Resources Information Center

    Thandi, Harch; Sharma, Raj

    2004-01-01

    This is a survey of MBA students' preparedness for launching new business initiatives or other entrepreneurial activities. It explores the readiness of the MBA students, estimated on dimensions comprising knowledge, attitude, skills,experience, opportunity and networks. The variation of the postgraduate students' perceptions along these six…

  1. 77 FR 38248 - Passenger Train Emergency Preparedness

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... rule on passenger train emergency preparedness that was codified at 49 CFR part 239. See 63 FR 24629... evacuate passengers. See 73 FR 6369 (February 1, 2008). While this final rule did not make any changes to... existing requirements as well as create new requirements for passenger train emergency systems. See 77...

  2. Disaster Preparedness and the Cooperative Extension Service

    ERIC Educational Resources Information Center

    Black, Lynette

    2012-01-01

    This past decade has recorded an increase in catastrophic events that have led to dramatic changes for Americans. The wake of these disasters has resulted in many lessons being learned. These lessons have been captured by Homeland Security in the First Edition of the National Preparedness Goal. Extension is uniquely positioned to assist with…

  3. Teaching Disaster Preparedness in Geographic Education

    ERIC Educational Resources Information Center

    Fuhrmann, Sven; Stone, Lee D.; Casey, Melinda C.; Curtis, Mary D.; Doyle, Amber L.; Earle, Brian D.; Jones, Douglas D.; Rodriguez, Philip; Schermerhorn, Steven M.

    2008-01-01

    Extreme natural and human-made disasters can affect the lives of thousands of citizens. The only way we can prepare ourselves for such situations is to learn and establish basic survival strategies within our families and communities. This article explores how K-12 teachers could help educating children about disaster preparedness by utilizing…

  4. 33 CFR 101.300 - Preparedness communications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the AMS Plan. (b) Communication of threats. When the COTP is made aware of a threat that may cause a... MARITIME SECURITY MARITIME SECURITY: GENERAL Communication (Port-Facility-Vessel) § 101.300 Preparedness... plan under parts 104 or 105 of this subchapter affected by a change in the MARSEC Level must...

  5. Using quality improvement methods to improve public health emergency preparedness: PREPARE for Pandemic Influenza.

    PubMed

    Lotstein, Debra; Seid, Michael; Ricci, Karen; Leuschner, Kristin; Margolis, Peter; Lurie, Nicole

    2008-01-01

    Many public health departments seek to improve their capability to respond to large-scale events such as an influenza pandemic. Quality improvement (QI), a structured approach to improving performance, has not been widely applied in public health. We developed and tested a pilot QI collaborative to explore whether QI could help public health departments improve their pandemic preparedness. We demonstrated that this is a promising model for improving public health preparedness and may be useful for improving public health performance overall. Further efforts are needed, however, to encourage the robust implementation of QI in public health. PMID:18628274

  6. Advances in Monitoring, Modelling and Forecasting Volcanic Ash Plumes over the Past 5 Years and the Impact on Preparedness from the London VAAC Perspective

    NASA Astrophysics Data System (ADS)

    Lee, D. S.; Lisk, I.

    2015-12-01

    Hosted and run by the Met Office, the London VAAC (Volcanic Ash Advisory Centre) is responsible for issuing advisories on the location and likely dispersion of ash clouds originating from volcanoes in the North East Atlantic, primarily from Iceland. These advisories and additional guidance products are used by the civil aviation community to make decisions on airspace flight management. London VAAC has specialist forecasters who use a combination of volcano source data, satellite-based, ground-based and aircraft observations, weather forecast models and dispersion models. Since the eruption of the Icelandic volcano Eyjafjallajökull in 2010, which resulted in the decision by many northern European countries to impose significant restrictions on the use of their airspace, London VAAC has been active in further developing its volcanic ash monitoring, modelling and forecasting capabilities, collaborating with research organisations, industry, other VAACs, Meteorological Services and the Volcano Observatory in Iceland. It has been necessary to advance operational capabilities to address evolving requirements, including for more quantitative assessments of volcanic ash in the atmosphere. Here we summarise advances in monitoring, modelling and forecasting of volcanic ash plumes over the past 5 years from the London VAAC perspective, and the realization of science into operations. We also highlight the importance of collaborative activities, such as the 'VAAC Best Practice' Workshop, where information is exchanged between all nine VAACs worldwide on the operational practices in monitoring and forecasting volcanic ash, with the aim of working toward a more harmonized service for decision makers in the aviation community. We conclude on an evaluation of how better we are prepared for the next significant ash-rich Icelandic eruption, and the challenges still remaining.

  7. Learning Environment, Preparedness and Satisfaction in Osteopathy in Europe: The PreSS Study

    PubMed Central

    Luciani, Emanuele; van Dun, Patrick L. S.; Esteves, Jorge Eduardo; Lunghi, Christian; Petracca, Marco; Papa, Liria; Merdy, Olivier; Jäkel, Anne; Cerritelli, Francesco

    2015-01-01

    Objective 1) to assess the preparedness to practice and satisfaction in learning environment amongst new graduates from European osteopathic institutions; 2) to compare the results of preparedness to practice and satisfaction in learning environment between and within countries where osteopathy is regulated and where regulation is still to be achieved; 3) to identify possible correlations between learning environment and preparedness to practice. Method Osteopathic education providers of full-time education located in Europe were enrolled, and their final year students were contacted to complete a survey. Measures used were: Dundee Ready Educational Environment Measure (DREEM), the Association of American Medical Colleges (AAMC) and a demographic questionnaire. Scores were compared across institutions using one-way ANOVA and generalised linear model. Results Nine European osteopathic education institutions participated in the study (4 located in Italy, 2 in the UK, 1 in France, 1 in Belgium and 1 in the Netherlands) and 243 (77%) of their final-year students completed the survey. The DREEM total score mean was 121.4 (SEM: 1.66) whilst the AAMC was 17.58 (SEM:0.35). A generalised linear model found a significant association between not-regulated countries and total score as well as subscales DREEM scores (p<0.001). Learning environment and preparedness to practice were significantly positively correlated (r=0.76; p<0.01). Discussion A perceived higher level of preparedness and satisfaction was found amongst students from osteopathic institutions located in countries without regulation compared to those located in countries where osteopathy is regulated; however, all institutions obtained a ‘more positive than negative’ result. Moreover, in general, cohorts with fewer than 20 students scored significantly higher compared to larger student cohorts. Finally, an overall positive correlation between students’ preparedness and satisfaction were found across all

  8. The U.S. National Tsunami Hazard Mitigation Program: Successes in Tsunami Preparedness

    NASA Astrophysics Data System (ADS)

    Whitmore, P.; Wilson, R. I.

    2012-12-01

    Formed in 1995 by Congressional Action, the National Tsunami Hazards Mitigation Program (NTHMP) provides the framework for tsunami preparedness activities in the United States. The Program consists of the 28 U.S. coastal states, territories, and commonwealths (STCs), as well as three Federal agencies: the National Oceanic and Atmospheric Administration (NOAA), the Federal Emergency Management Agency (FEMA), and the United States Geological Survey (USGS). Since its inception, the NTHMP has advanced tsunami preparedness in the United States through accomplishments in many areas of tsunami preparedness: - Coordination and funding of tsunami hazard analysis and preparedness activities in STCs; - Development and execution of a coordinated plan to address education and outreach activities (materials, signage, and guides) within its membership; - Lead the effort to assist communities in meeting National Weather Service (NWS) TsunamiReady guidelines through development of evacuation maps and other planning activities; - Determination of tsunami hazard zones in most highly threatened coastal communities throughout the country by detailed tsunami inundation studies; - Development of a benchmarking procedure for numerical tsunami models to ensure models used in the inundation studies meet consistent, NOAA standards; - Creation of a national tsunami exercise framework to test tsunami warning system response; - Funding community tsunami warning dissemination and reception systems such as sirens and NOAA Weather Radios; and, - Providing guidance to NOAA's Tsunami Warning Centers regarding warning dissemination and content. NTHMP activities have advanced the state of preparedness of United States coastal communities, and have helped save lives and property during recent tsunamis. Program successes as well as future plans, including maritime preparedness, are discussed.

  9. Assessing and improving cross-border chemical incident preparedness and response across Europe.

    PubMed

    Stewart-Evans, James; Hall, Lisbeth; Czerczak, Slawomir; Manley, Kevin; Dobney, Alec; Hoffer, Sally; Pałaszewska-Tkacz, Anna; Jankowska, Agnieszka

    2014-11-01

    Good practices in emergency preparedness and response for chemical incidents include practices specific to the different functions of exposure assessment (e.g., within the monitoring function, the use of mobile monitoring equipment; within the modelling function, the use of rapid dispersion models with integrated mapping software) and generic practices to engage incident response stakeholders to maximise exposure assessment capabilities (e.g., sharing protocols and pre-prepared information and multi-agency training and exercising). Such practices can optimise cross-border collaboration. A wide range of practices have been implemented across MSs during chemical incident response, particularly during incidents that have cross-border and trans-boundary impacts. This paper proposes a self-assessment methodology to enable MSs, or organisations within MSs, to examine exposure assessment capabilities and communication pathways between exposure assessors and public health risk assessors. Where gaps exist, this methodology provides links to good practices that could improve response, communication and collaboration across local, regional and national borders. A fragmented approach to emergency preparedness for chemical incidents is a major obstacle to improving cross-border exposure assessment. There is no one existing body or structure responsible for all aspects of chemical incident preparedness and response in the European Union. Due to the range of different organisations and networks involved in chemical incident response, emergency preparedness needs to be drawn together. A number of recommendations are proposed, including the use of networks of experts which link public health risk assessors with experts in exposure assessment, in order to coordinate and improve chemical incident emergency preparedness. The EU's recent Decision on serious cross-border threats to health aims to facilitate MSs' compliance with the International Health Regulations, which require

  10. Application of Behavioral Theories to Disaster and Emergency Health Preparedness: A Systematic Review

    PubMed Central

    Ejeta, Luche Tadesse; Ardalan, Ali; Paton, Douglas

    2015-01-01

    Background: Preparedness for disasters and emergencies at individual, community and organizational levels could be more effective tools in mitigating (the growing incidence) of disaster risk and ameliorating their impacts. That is, to play more significant roles in disaster risk reduction (DRR). Preparedness efforts focus on changing human behaviors in ways that reduce people’s risk and increase their ability to cope with hazard consequences. While preparedness initiatives have used behavioral theories to facilitate DRR, many theories have been used and little is known about which behavioral theories are more commonly used, where they have been used, and why they have been preferred over alternative behavioral theories. Given that theories differ with respect to the variables used and the relationship between them, a systematic analysis is an essential first step to answering questions about the relative utility of theories and providing a more robust evidence base for preparedness components of DRR strategies. The goal of this systematic review was to search and summarize evidence by assessing the application of behavioral theories to disaster and emergency health preparedness across the world. Methods: The protocol was prepared in which the study objectives, questions, inclusion and exclusion criteria, and sensitive search strategies were developed and pilot-tested at the beginning of the study. Using selected keywords, articles were searched mainly in PubMed, Scopus, Mosby’s Index (Nursing Index) and Safetylit databases. Articles were assessed based on their titles, abstracts, and their full texts. The data were extracted from selected articles and results were presented using qualitative and quantitative methods. Results: In total, 2040 titles, 450 abstracts and 62 full texts of articles were assessed for eligibility criteria, whilst five articles were archived from other sources, and then finally, 33 articles were selected. The Health Belief Model (HBM

  11. A Solutions Network for Disaster Preparedness and Response

    NASA Astrophysics Data System (ADS)

    Bhaduri, B.; Tuttle, M.; Fernandez, S.

    2008-05-01

    Careful planning and management strategies are essential for disaster preparedness and prevention and to the implementation of responses strategies when emergencies do occur. Disasters related to climate and weather extremes, such as hurricanes, floods, wildfires, blizzards, droughts, and tornadoes may have a period for watching and warning within which emergency preparedness measures can be taken to reduce risk to population and critical infrastructures. The ability to effectively address emergency preparedness and response operations is dependent upon a strong global spatial data infrastructure, and geospatial modeling and simulation capabilities that can complement the decision making process at various stages of disaster preparedness, response, and recovery. It is well understood that a strong linkage between data and analytical capabilities are nucleus to effective decision making ability and that disaster consequence management organizations should have access to the best available geospatial technical expertise, global and regional data sets, and modeling and analytical tools. However, such optimal combination of data assets and modeling expertise are often beyond the resources available internally within a single organization but can be accessed through external collaboration with other "Earth science community-of-practice" organizations. This provides an opportunity to develop a solutions network for disaster preparedness and response. However, our current capability and state of general practice in disaster consequence management is, for the most part, built around such networks that are not very well defined, often formed on an ad-hoc basis soon after a disaster, loosely coupled, and functions at less than desirable pace. We will illustrate this concept of a solutions network through the current functions of the Visualization and Modeling Working Group (VMWG) of the Department of Energy, to which multiple national laboratories and other federal agencies

  12. Promoting Career Preparedness and Intrinsic Work-Goal Motivation: RCT Intervention

    ERIC Educational Resources Information Center

    Salmela-Aro, Katariina; Mutanen, Pertti; Vuori, Jukka

    2012-01-01

    We examined the role of an in-company training program aimed at enhancing employees' intrinsic work-goal motivation by increasing their career preparedness in a randomized field experimental study. The program activities were implemented using an organization-level two-trainer model with trainers from the human resources management and…

  13. The Effect of Coping Knowledge on Emergency Preparedness in Elementary School Students

    ERIC Educational Resources Information Center

    Kim, Shin-Jeong; Kang, So-Ra; Lee, Seung-Hee; Kang, Kyung-Ah

    2014-01-01

    The purpose of this study was to examine the effect of coping knowledge for emergency preparedness in Korean elementary school students. A school-based coping education program was provided seven times to 271 fourth- and fifth-grade students in two urban schools by researchers with the school nurses. The Process Model of Stress and Coping and…

  14. Communications in Public Health Emergency Preparedness: A Systematic Review of the Literature

    PubMed Central

    Savoia, Elena; Viswanath, Kasisomayajula

    2013-01-01

    During a public health crisis, public health agencies engage in a variety of public communication efforts to inform the population, encourage the adoption of preventive behaviors, and limit the impact of adverse events. Given the importance of communication to the public in public health emergency preparedness, it is critical to examine the extent to which this field of study has received attention from the scientific community. We conducted a systematic literature review to describe current research in the area of communication to the public in public health emergency preparedness, focusing on the association between sociodemographic and behavioral factors and communication as well as preparedness outcomes. Articles were searched in PubMed and Embase and reviewed by 2 independent reviewers. A total of 131 articles were included for final review. Fifty-three percent of the articles were empirical, of which 74% were population-based studies, and 26% used information environment analysis techniques. None had an experimental study design. Population-based studies were rarely supported by theoretical models and mostly relied on a cross-sectional study design. Consistent results were reported on the association between population socioeconomic factors and public health emergency preparedness communication and preparedness outcomes. Our findings show the need for empirical research to determine what type of communication messages can be effective in achieving preparedness outcomes across various population groups. They suggest that a real-time analysis of the information environment is valuable in knowing what is being communicated to the public and could be used for course correction of public health messages during a crisis. PMID:24041193

  15. Emergency mitigation and preparedness in healthcare facilities.

    PubMed

    Paras, Emma; Schwartz, Robert M

    2013-01-01

    The city of Akron, Ohio, has four major healthcare facilities: Akron General Medical Center, Summa Akron City Hospital, Summa St. Thomas, and Akron Children's Hospital. These institutions have implemented the preparedness and mitigative strategies to prepare for hazards affecting the community. Because of the wide population these facilities serve, it is crucial that an effective emergency management (EM) system be in place at each hospital. Archival research and interviews with the emergency managers of each hospital examine the preparedness of these establishments for disasters. Strengths and weaknesses of the EM systems are also discussed and include recommendations on ways to improve shortcomings. This research demonstrates how EM is evolving and improving in one of the most important critical infrastructure of a community. PMID:24623110

  16. Raising risk preparedness through flood risk communication

    NASA Astrophysics Data System (ADS)

    Maidl, E.; Buchecker, M.

    2014-01-01

    During the last decade, most European countries have produced risk maps of natural hazards, but little is known about how to communicate these maps most effectively to the public. In October 2011, Zurich's local authorities informed owners of buildings located in the urban flood hazard area about potential flood damage, the probability of flood events and protection measures. The campaign was based on the assumptions that informing citizens increases their risk awareness and that citizens who are aware of risks are more likely to undertake appropriate actions to protect themselves and their property. This study is intended as a contribution to a better understanding the factors influencing flood risk preparedness, with a special focus on the effects of such a one-way risk communication strategy. We conducted a standardized mail survey of 1500 property owners in the hazard areas in Zurich. The questionnaire comprised items measuring respondents' risk awareness, risk preparedness, flood experience, information seeking behaviour, knowledge about flood risk, evaluation of the information material, risk acceptance, kind of property owned, attachment to the property, trust in local authorities, and socio-demographic variables. Multivariate data analysis revealed that the average level of risk awareness and preparedness was low, but our results confirmed that the campaign had a statistically significant effect on the level of preparedness. The main factors influencing the respondents' intention to prepare for a flood were the extent to which they evaluated the information material positively and their risk awareness. Those who had never taken any interest in floods previously were less likely to read the material. For future campaigns, we therefore recommend repeated communication of relevant information tailored to the needs of the target population.

  17. Raising risk preparedness by flood risk communication

    NASA Astrophysics Data System (ADS)

    Maidl, E.; Buchecker, M.

    2015-07-01

    During the last decade, most European countries have produced hazard maps of natural hazards, but little is known about how to communicate these maps most efficiently to the public. In October 2011, Zurich's local authorities informed owners of buildings located in the urban flood hazard zone about potential flood damage, the probability of flood events and protection measures. The campaign was based on the assumptions that informing citizens increases their risk awareness and that citizens who are aware of risks are more likely to undertake actions to protect themselves and their property. This study is intended as a contribution to better understand the factors that influence flood risk preparedness, with a special focus on the effects of such a one-way risk communication strategy. We conducted a standardized mail survey of 1500 property owners in the hazard zones in Zurich (response rate main survey: 34 %). The questionnaire included items to measure respondents' risk awareness, risk preparedness, flood experience, information-seeking behaviour, knowledge about flood risk, evaluation of the information material, risk acceptance, attachment to the property and trust in local authorities. Data about the type of property and socio-demographic variables were also collected. Multivariate data analysis revealed that the average level of risk awareness and preparedness was low, but the results confirmed that the campaign had a statistically significant effect on the level of preparedness. The main influencing factors on the intention to prepare for a flood were the extent to which respondents evaluated the information material positively as well as their risk awareness. Respondents who had never taken any previous interest in floods were less likely to read the material. For future campaigns, we therefore recommend repeated communication that is tailored to the information needs of the target population.

  18. South Carolina Area Health Education Consortium Disaster Preparedness and Response Training Network: an emerging partner in preparedness training.

    PubMed

    Kennedy, Beth; Carson, Deborah Stier; Garr, David

    2009-03-01

    The South Carolina Area Health Education Consortium (SC AHEC) was funded in 2003 to train healthcare professionals in disaster preparedness and response. During the 5 years of funding, its Disaster Preparedness and Response Training Network evolved from disaster awareness training to competency-based instruction and performance assessment. With funding from the assistant secretary for preparedness and response (ASPR), a project with implications for national dissemination was developed to evaluate 2 aspects of preparedness training for community-based healthcare professionals. The SC AHEC designed disaster preparedness curricula and lesson plans, using a consensus-building technique, and then (1) distributed sample curricula and resources through the national Area Health Education Center system to assess an approach for providing preparedness training and (2) delivered a standardized preparedness curriculum to key influential thought leaders from 4 states to evaluate the effectiveness and acceptability of the curriculum. As a result of this project, the SC AHEC recommends that preparedness training for community-based practitioners needs to be concise and professionally relevant. It should be integrated into existing healthcare professions education programs and continuing education offerings. The project also demonstrated that although AHECs may be interested and well suited to incorporate preparedness training as part of their mission, more work needs to be done if they are to assume a prominent role in disaster preparedness training. PMID:19202395

  19. Differences Between US and UK Adults in Stroke Preparedness

    PubMed Central

    Ford, Gary A.; Morgenstern, Lewis B.; White, Martin; Sniehotta, Falko F.; Mackintosh, Joan E.; Gellert, Paul; Skolarus, Lesli E.

    2015-01-01

    Background and Purpose— Although time-dependent treatment is available, most people delay contacting emergency medical services for stroke. Given differences in the healthcare system and public health campaigns, exploring between-country differences in stroke preparedness may identify novel ways to increase acute stroke treatment. Methods— A survey was mailed to population-based samples in Ingham County, Michigan, US (n=2500), and Newcastle upon Tyne, UK (n=2500). Surveys included stroke perceptions and stroke/nonstroke scenarios to assess recognition and response to stroke. Between-country differences and associations with stroke preparedness were examined using t tests and linear mixed models. Results— Overall response rate was 27.4%. The mean age of participants was 55 years, and 58% were female. US participants were better in recognizing stroke (70% versus 63%, d=0.27) and were more likely to call emergency medical services (55% versus 52%, d=0.11). After controlling for demographics and comorbidities, US participants remained more likely to recognize stroke but were not more likely to respond appropriately. A greater belief that medical treatment can help with stroke and understanding of stroke was associated with improved stroke recognition and response. Conclusions— Overall, stroke recognition and response were moderate. US participants were modestly better at recognizing stroke, although there was little difference in response to stroke. Future stroke awareness interventions could focus more on stroke outcome expectations and developing a greater understanding of stroke among the public. PMID:26419968

  20. Acquired reactive perforating collagenosis.

    PubMed

    Basak, P Y; Turkmen, C

    2001-01-01

    Acquired perforating disorder has been recognized as an uncommon distinct dermatosis in which altered collagen is eliminated through the epidermis. Several disorders accompanied by itching and scratching were reported to be associated with reactive perforating collagenosis. A 67-year-old white woman diagnosed as acquired reactive perforating collagenosis with poorly controlled diabetes mellitus and congestive cardiac failure is presented. PMID:11525959

  1. The use of the WGM2012 gravity model to acquire gravimetric data necessary for the reduction of geodetic observations

    NASA Astrophysics Data System (ADS)

    Olszak, Tomasz; Barlik, Marcin

    2014-05-01

    World Gravity Model WGM2012 is the first release of high resolution description inter alia Bouguer and free-air gravity anomaly. It has been created by the Bureau Gravimétrique International (BGI) on base of EGM2008 geopotential model and high resolution topographic model. The poster provides an assessment of the WGM2012 gravity data sources for use in the reduction of geodetic observations. For reductions of geodetic observations onto geoid and ellipsoid (eg. astronomical coordinates, deflections of the vertical, astronomical azimuth and linear measurements) it is necessary a knowledge of the gravity field parameters. Also, in the leveling network it is necessary to collect such information to calculate the normal (or orthometric) correction. The study compared terrestrial data from the Polish National Geological Institute including anomalies and data from the WGM2012 model in the context of using model gravity data to issues related to geodesic reductions.

  2. Exploring the Predictors of Organizational Preparedness for Natural Disasters.

    PubMed

    Sadiq, Abdul-Akeem; Graham, John D

    2016-05-01

    There is an extensive body of research on the determinants of disaster preparedness at the individual and household levels. The same cannot be said for the organizational level. Hence, the purpose of this study is to shed light on the predictors of organizational preparedness for natural disasters. Since leaders of organizations have an incentive to overstate their level of preparedness and because surveys of organizational leaders suffer from selection bias and low response rates, we take the novel approach of interviewing employees about the organizations that employ them. Using an online survey, we collected information from a national sample of 2,008 U.S. employees and estimated the predictors of preparedness at the organizational level. We find, among other results, that organization size (facility level) is a consistent predictor of preparedness at the organizational level. We conclude with policy recommendations and outline an agenda for future research on organizational preparedness for natural disasters. PMID:26332326

  3. Vested interest, disaster preparedness, and strategic campaign message design.

    PubMed

    Adame, Bradley J; Miller, Claude H

    2015-01-01

    In recent years, the United States has recognized an increasing need for individual-level disaster preparedness, with federal, state, and local government agencies finding only limited success in instituting campaign-based disaster preparedness programs. Extant research indicates Americans generally remain poorly informed and badly unprepared for imminent disasters. Vested interest theory (Crano, 1997) is presented as a framework for designing and testing the effectiveness of television-based disaster preparedness campaign messages. High- and low-vested versions of an extant control message are compared to assess message efficacy as indicated by behavioral intentions, message acceptance, and preparedness related attitudes. Results indicate television-based video public service announcements manipulated with subtle message variations can be effective at influencing critical preparedness-related attitudes. The high-vested condition performed significantly better than the low-vested and control conditions for both behavioral intentions and perceptions of self-efficacy, two vitally important outcome variables associated with disaster preparedness. PMID:24837442

  4. Downsizer - A Graphical User Interface-Based Application for Browsing, Acquiring, and Formatting Time-Series Data for Hydrologic Modeling

    USGS Publications Warehouse

    Ward-Garrison, Christian; Markstrom, Steven L.; Hay, Lauren E.

    2009-01-01

    The U.S. Geological Survey Downsizer is a computer application that selects, downloads, verifies, and formats station-based time-series data for environmental-resource models, particularly the Precipitation-Runoff Modeling System. Downsizer implements the client-server software architecture. The client presents a map-based, graphical user interface that is intuitive to modelers; the server provides streamflow and climate time-series data from over 40,000 measurement stations across the United States. This report is the Downsizer user's manual and provides (1) an overview of the software design, (2) installation instructions, (3) a description of the graphical user interface, (4) a description of selected output files, and (5) troubleshooting information.

  5. Diphtheria Toxin- and GFP-Based Mouse Models of Acquired Hypoparathyroidism and Treatment With a Long-Acting Parathyroid Hormone Analog.

    PubMed

    Bi, Ruiye; Fan, Yi; Lauter, Kelly; Hu, Jing; Watanabe, Tomoyuki; Cradock, Jim; Yuan, Quan; Gardella, Thomas; Mannstadt, Michael

    2016-05-01

    Hypoparathyroidism (HP) arises most commonly from parathyroid (PT) gland damage associated with neck surgery, and is typically treated with oral calcium and active vitamin D. Such treatment effectively increases levels of serum calcium (sCa), but also brings risk of hypercalciuria and renal damage. There is thus considerable interest in using PTH or PTH analogs to treat HP. To facilitate study of this disease and the assessment of new treatment options, we developed two mouse models of acquired HP, and used them to assess efficacy of PTH(1-34) as well as a long-acting PTH analog (LA-PTH) in regulating blood calcium levels. In one model, we used PTHcre-iDTR mice in which the diphtheria toxin (DT) receptor (DTR) is selectively expressed in PT glands, such that systemic DT administration selectively ablates parathyroid cells. For the second model, we generated GFP-PT mice in which green fluorescent protein (GFP) is selectively expressed in PT cells, such that parathyroidectomy (PTX) is facilitated by green fluorescence of the PT glands. In the PTHcre-iDTR mice, DT injection (2 × 5 μg/kg, i.p.) resulted in moderate yet consistent reductions in serum PTH and sCa levels. The more severe hypoparathyroid phenotype was observed in GFP-PT mice following GFP-guided PTX surgery. In each model, a single subcutaneous injection of LA-PTH increased sCa levels more effectively and for a longer duration (>24 hours) than did a 10-fold higher dose of PTH(1-34), without causing excessive urinary calcium excretion. These new mouse models thus faithfully replicate two degrees of acquired HP, moderate and severe, and may be useful for assessing potential new modes of therapy. © 2015 American Society for Bone and Mineral Research. PMID:26678919

  6. Semivariogram functions usage for a surface modeling with kriging method using data acquired with GNSS satellite method

    NASA Astrophysics Data System (ADS)

    Pająk, Katarzyna; Glazer, Anna

    2013-04-01

    The subject of the paper is creating a land surface representation in the form of DTM (digital terrain model), widely used in many areas nowadays - from the environment protection through engineering projects to the innovative military applications. The aim of the paper is to present the possibilities of using geostatistical interpolation method - kriging in the process of generating digital terrain models. Kriging interpolation begins with the analysis of spatial data structures, figured with the means of so-called. semivariogram. The semivariogram is used in the estimation of an unknown variable, which is the height in the DTM. A hypothesis connected with the theoretical semivariogram selection on the interpolation accuracy was verified, and thus also the accuracy of the resulting terrain model. The size of this effect was determined with two parameters: the kriging variance and root-mean-square error (RMS). The accuracy of the surface modeling is based on, inter alia, the nature of the study area. The method has been used for a DTM geostatistical construction based on source data that came from RTK GNSS satellite measurements.

  7. Animal models of Central Diabetes Insipidus: Human relevance of acquired beyond hereditary syndromes and the role of oxytocin.

    PubMed

    Bernal, Antonio; Mahía, Javier; Puerto, Amadeo

    2016-07-01

    The aim of this study was to review different animal models of Central Diabetes Insipidus, a neurobiological syndrome characterized by the excretion of copious amounts of diluted urine (polyuria), a consequent water intake (polydipsia), and a rise in the serum sodium concentration (hypernatremia). In rodents, Central Diabetes Insipidus can be caused by genetic disorders (Brattleboro rats) but also by various traumatic/surgical interventions, including neurohypophysectomy, pituitary stalk compression, hypophysectomy, and median eminence lesions. Regardless of its etiology, Central Diabetes Insipidus affects the neuroendocrine system that secretes arginine vasopressin, a neurohormone responsible for antidiuretic functions that acts trough the renal system. However, most Central Diabetes Insipidus models also show disorders in other neurobiological systems, specifically in the secretion of oxytocin, a neurohormone involved in body sodium excretion. Although the hydromineral behaviors shown by the different Central Diabetes Insipidus models have usually been considered as very similar, the present review highlights relevant differences with respect to these behaviors as a function of the individual neurobiological systems affected. Increased understanding of the relationship between the neuroendocrine systems involved and the associated hydromineral behaviors may allow appropriate action to be taken to correct these behavioral neuroendocrine deficits. PMID:27118135

  8. Acquired Cystic Kidney Disease

    MedlinePlus

    ... a kidney transplant or blood-filtering treatments called dialysis. The cysts are more likely to develop in people who are on kidney dialysis. The chance of developing acquired cystic kidney disease ...

  9. Hospital-acquired pneumonia

    MedlinePlus

    ... tends to be more serious than other lung infections because: People in the hospital are often very sick and cannot fight off ... prevent pneumonia. Most hospitals have programs to prevent hospital-acquired infections.

  10. Computational representation and hemodynamic characterization of in vivo acquired severe stenotic renal artery geometries using turbulence modeling.

    PubMed

    Kagadis, George C; Skouras, Eugene D; Bourantas, George C; Paraskeva, Christakis A; Katsanos, Konstantinos; Karnabatidis, Dimitris; Nikiforidis, George C

    2008-06-01

    The present study reports on computational fluid dynamics in the case of severe renal artery stenosis (RAS). An anatomically realistic model of a renal artery was reconstructed from CT scans, and used to conduct CFD simulations of blood flow across RAS. The recently developed shear stress transport (SST) turbulence model was pivotally applied in the simulation of blood flow in the region of interest. Blood flow was studied in vivo under the presence of RAS and subsequently in simulated cases before the development of RAS, and after endovascular stent implantation. The pressure gradients in the RAS case were many orders of magnitude larger than in the healthy case. The presence of RAS increased flow resistance, which led to considerably lower blood flow rates. A simulated stent in place of the RAS decreased the flow resistance at levels proportional to, and even lower than, the simulated healthy case without the RAS. The wall shear stresses, differential pressure profiles, and net forces exerted on the surface of the atherosclerotic plaque at peak pulse were shown to be of relevant high distinctiveness, so as to be considered potential indicators of hemodynamically significant RAS. PMID:17714975

  11. Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.

    PubMed

    Liu, Shi-Jie; Zheng, Ping; Wright, David K; Dezsi, Gabi; Braine, Emma; Nguyen, Thanh; Corcoran, Niall M; Johnston, Leigh A; Hovens, Christopher M; Mayo, Jamie N; Hudson, Matthew; Shultz, Sandy R; Jones, Nigel C; O'Brien, Terence J

    2016-07-01

    There are no treatments in clinical practice known to mitigate the neurobiological processes that convert a healthy brain into an epileptic one, a phenomenon known as epileptogenesis. Downregulation of protein phosphatase 2A, a protein that causes the hyperphosphorylation of tau, is implicated in neurodegenerative diseases commonly associated with epilepsy, such as Alzheimer's disease and traumatic brain injury. Here we used the protein phosphatase 2A activator sodium selenate to investigate the role of protein phosphatase 2A in three different rat models of epileptogenesis: amygdala kindling, post-kainic acid status epilepticus, and post-traumatic epilepsy. Protein phosphatase 2A activity was decreased, and tau phosphorylation increased, in epileptogenic brain regions in all three models. Continuous sodium selenate treatment mitigated epileptogenesis and prevented the biochemical abnormalities, effects which persisted after drug withdrawal. Our studies indicate that limbic epileptogenesis is associated with downregulation of protein phosphatase 2A and the hyperphosphorylation of tau, and that targeting this mechanism with sodium selenate is a potential anti-epileptogenic therapy. PMID:27289302

  12. 75 FR 42448 - Board of Scientific Counselors, Coordinating Office for Terrorism Preparedness and Emergency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... Office for Terrorism Preparedness and Emergency Response; Notice of Charter Amendment This gives notice... Scientific Counselors, Coordinating Office for Terrorism Preparedness and Emergency Response, Department...

  13. Evaluation of Structure from Motion Software to Create 3D Models of Late Nineteenth Century Great Lakes Shipwrecks Using Archived Diver-Acquired Video Surveys

    NASA Astrophysics Data System (ADS)

    Mertes, J.; Thomsen, T.; Gulley, J.

    2014-12-01

    Here we demonstrate the ability to use archived video surveys to create photorealistic 3D models of submerged archeological sites. We created 3D models of two nineteenth century Great Lakes shipwrecks using diver-acquired video surveys and Structure from Motion (SfM) software. Models were georeferenced using archived hand survey data. Comparison of hand survey measurements and digital measurements made using the models demonstrate that spatial analysis produces results with reasonable accuracy when wreck maps are available. Error associated with digital measurements displayed an inverse relationship to object size. Measurement error ranged from a maximum of 18 % (on 0.37 m object) and a minimum of 0.56 % (on a 4.21 m object). Our results demonstrate SfM can generate models of large maritime archaeological sites that for research, education and outreach purposes. Where site maps are available, these 3D models can be georeferenced to allow additional spatial analysis long after on-site data collection.

  14. Integrating Local, National, and International Stakeholders in Outbreak Preparedness in Developing Countries: Conclusions from a Conference in Mbeya, Tanzania.

    PubMed

    Froeschl, Guenter; Ntinginya, Nyanda Elias; Sangare, Anthony; Lawala, Paul; Mangu, Chacha; Dobler, Gerhard; Heinrich, Norbert; Flach, Britta; Nsojo, Anthony; Lennemann, Tessa

    2016-01-01

    A conference called "Outbreaks in Tanzania-Are We Prepared?" was held in Mbeya, Tanzania, on September 14 and 15, 2015, accompanied by a training workshop on infection prevention and control for local stakeholders from September 16 to 18, 2015. The objective of the conference was to revisit past disease epidemics and to reflect on the current status of surveillance and outbreak preparedness in Tanzania, including an overview of agents relevant to biosecurity. The conference brought together national authorities of Tanzania, regional public health representatives, people from research and academic institutions, and international stakeholders. Key findings of the event were: (1) although national frameworks for surveillance and preparedness exist, their implementation presents challenges, and local health structures need support in implementation; (2) the ability to identify and properly manage infectious diseases of public health concern is crucial in empowering the local health workforce to contribute to surveillance measures, which in turn allows for realistic risk assessments and management algorithms; and (3) in settings of limited resources, research activities acquire an additional responsibility toward national surveillance and capacity building and should be integrated into national epidemic preparedness plans. This event was the first of its kind in Tanzania, facilitating direct discussion among regional, zonal, national, and international stakeholders on surveillance and outbreak preparedness. The conference's conclusions are relevant to strengthening health systems in other low- and middle-income countries. PMID:26836445

  15. MC32 tumor cells acquire Ag-specific CTL resistance through the loss of CEA in a colon cancer model

    PubMed Central

    Lee, Sang-Yeul; Sin, Jeong-Im

    2015-01-01

    We previously reported that MC32 cells resist carcinoembryonic antigen (CEA) DNA vaccination by losing their antigen presentation to Ag-specific CTLs in the context of MHC class I antigens in a colon cancer therapeutic model. In this study, we selected 2 tumor cells, MC32-S2–2 and MC32-S4–2, which have the ability to form tumors in CEA DNA vaccine-immunized mice. Wild type MC32 cells grew significantly less in CEA-immunized mice (with Ag-specific CTL lytic activity) than in control mice (with no Ag-specific CTL lytic activity). However, MC32-S2–2 and MC32-S4–2 cells grew at a similar rate in both control and CEA-immunized mice, confirming their resistant status against CEA DNA vaccination. MC32-S2–2 and MC32-S4–2 cells were not susceptible to lysis by CEA-specific CD8+ T cells. Moreover, when MC32-S2–2 and MC32-S4–2 cells were used as stimulating agents of CEA-specific immune cells for IFN-γ production, these cells failed to stimulate the induction of Ag-specific IFN-γ, suggesting a loss of tumor cell recognition by Ag-specific immune cells. However, MC32-S2–2 and MC32-S4–2 cells expressed MHC class I antigens in a manner similar to that of wild type MC32 cells. Finally, Western blot assay confirmed that in MC32-S2–2 and MC32-S4–2 cells, CEA expression remained absent but mouse CEA was expressed. Taken together, these data show that MC32 cells may also be able to achieve resistance to CEA-specific CTLs by antigen loss in this model. PMID:25902414

  16. Sandia National Laboratories approach to emergency preparedness

    SciTech Connect

    Galegar, F.H.; Yourick, P.D.; Ross, S.A.

    1997-12-31

    Sandia National Laboratories is located on Kirtland AFB on Albuquerque, NM. The Air Force Base proper covers about 74 square miles in which SNL maintains 5 technical areas and the Coyote Test Field. These SNL areas add up to about 18,000 acres. However, SNL has other locations where we conduct corporate emergency planning: Kauai Test Facility (at Pacific Missile Range Facility in Kauai, Hawaii), and the Tonopah Test Range (Nevada). SNL/California located in Livermore has an independent emergency preparedness organization for their emergency planning activities.

  17. Preparedness 3.0: Addressing the Future.

    PubMed

    Benjamin, Georges C

    2015-12-01

    The last 14 years has taught us that that we are facing a new reality; a reality in which public health emergencies are a common occurrence. Today, we live in a world with dangerous people without state sponsorship who are an enormous threat to our safety; one where emerging and reemerging infectious diseases are waiting to break out; a world where the benefits of globalization in trade, transportation, and social media brings threats to our communities faster and with a greater risk than ever before. Even climate change has entered into the preparedness equation, bringing with it the forces of nature in the form of extreme weather and its complications. PMID:26545197

  18. An Incident Management Preparedness and Coordination Toolkit

    SciTech Connect

    Koch, Daniel B; Payne, Patricia W

    2012-01-01

    Although the use of Geographic Information Systems (GIS) by centrally-located operations staff is well established in the area of emergency response, utilization by first responders in the field is uneven. Cost, complexity, and connectivity are often the deciding factors preventing wider adoption. For the past several years, Oak Ridge National Laboratory (ORNL) has been developing a mobile GIS solution using free and open-source software targeting the needs of front-line personnel. Termed IMPACT, for Incident Management Preparedness and Coordination Toolkit, this ORNL application can complement existing GIS infrastructure and extend its power and capabilities to responders first on the scene of a natural or man-made disaster.

  19. State Health Policy for Terrorism Preparedness

    PubMed Central

    Ziskin, Leah Z.; Harris, Drew A.

    2007-01-01

    State health policy for terrorism preparedness began before the terrorist attacks on September 11, 2001, but was accelerated after that day. In a crisis atmosphere after September 11, the states found their policies changing rapidly, greatly influenced by federal policies and federal dollars. In the 5 years since September 11, these state health policies have been refined. This refinement has included a restatement of the goals and objectives of state programs, the modernization of emergency powers statutes, the education and training of the public health workforce, and a preparation of the health care system to better care for victims of disasters, including acts of terrorism. PMID:17666689

  20. Teaching Activities for Defensive Living and Emergency Preparedness. Education Modules.

    ERIC Educational Resources Information Center

    Peterson, Grit, Ed.; And Others

    Designed for teaching a generalized program in emergency preparedness education, the eight units of the manual can be used together or alone in any course that teaches human response to emergency preparedness or in physical education, recreation, health, biology, physiology, or science classes. The guide includes an introduction and seven major…

  1. 44 CFR 208.22 - Preparedness Cooperative Agreement process.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Preparedness Cooperative Agreement process. 208.22 Section 208.22 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE NATIONAL URBAN SEARCH AND RESCUE RESPONSE SYSTEM Preparedness Cooperative Agreements...

  2. Public health preparedness: a systems‐level approach

    PubMed Central

    Moore, Spencer; Mawji, Al; Shiell, Alan; Noseworthy, Tom

    2007-01-01

    Public health and emergency preparedness have become central concepts in the current restructuring of various regional‐, national‐ and global‐level public health and emergency management agencies and systems. In this article, a glossary of the most important terms and concepts currently pertaining to public health preparedness is provided with a focus on systems‐level and organisational issues. PMID:17372286

  3. Making Connections: A Network Approach to University Disaster Preparedness

    ERIC Educational Resources Information Center

    Stein, Catherine H.; Vickio, Craig J.; Fogo, Wendy R.; Abraham, Kristen M.

    2007-01-01

    A network approach to disaster preparedness in university settings is described. Basic network concepts relevant for disaster preparedness and methods for analyzing network data without complex mathematics are presented. A case study of campus mental health and academic units at a midwestern university is presented to illustrate the practical…

  4. Confidence and Preparedness to Teach: Conflicting Perspectives from Multiple Stakeholders

    ERIC Educational Resources Information Center

    Carter, Pamala J.; Cowan, Kay W.

    2013-01-01

    This article, "Confidence and Preparedness to Teach" is a quantitative study that examines the level of preparedness for the classroom of fifty-seven student teachers. The student teachers, their cooperating teachers, and the professor-in-residence who monitored the placement completed a twenty-four item survey that rated the prospective…

  5. Presidential Perspectives of Crisis Preparedness at Christian Higher Education Institutions

    ERIC Educational Resources Information Center

    Burrell, Stacy M.; Heiselt, April K.

    2012-01-01

    Crises, whether human or natural, occur on all college campuses. Extensive research has been conducted on crisis preparedness at four-year, nondenominational institutions. This study examined crisis preparedness at Christian institutions of higher education. The study examined the perspectives of presidents of Christian institutions of higher…

  6. 78 FR 32535 - National Hurricane Preparedness Week, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... Independence of the United States of America the two hundred and thirty- seventh. (Presidential Sig.) [FR Doc... May 30, 2013 Part II The President Proclamation 8986--National Hurricane Preparedness Week, 2013... 3-- #0;The President ] Proclamation 8986 of May 24, 2013 National Hurricane Preparedness Week,...

  7. 77 FR 32877 - National Hurricane Preparedness Week, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... United States of America the two hundred and thirty-sixth. (Presidential Sig.) [FR Doc. 2012-13515 Filed...#0;#0; ] Proclamation 8830 of May 25, 2012 National Hurricane Preparedness Week, 2012 By the... Preparedness Week, we rededicate ourselves to preventing loss of life and damage to property by...

  8. 75 FR 29389 - National Hurricane Preparedness Week, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... of America the two hundred and thirty-fourth. (Presidential Sig.) [FR Doc. 2010-12753 Filed 5-25-10... Preparedness Week, 2010 By the President of the United States of America A Proclamation Each year during... National Hurricane Preparedness Week, I urge individuals, families, communities, and businesses to...

  9. ROBO1, a tumor suppressor and critical molecular barrier for localized tumor cells to acquire invasive phenotype: Study in African-American and Caucasian prostate cancer models

    PubMed Central

    Parray, Aijaz; Siddique, Hifzur R.; Kuriger, Jacquelyn K.; Mishra, Shrawan K.; Rhim, Johng S.; Nelson, Heather H.; Aburatani, Hiroyuki; Konety, Badrinath R.; Koochekpour, Shahriar; Saleem, Mohammad

    2015-01-01

    High-risk populations exhibit early transformation of localized prostate cancer (CaP) disease to metastasis which results in the mortality of such patients. The paucity of knowledge about the molecular mechanism involved in acquiring of metastatic behavior by primary tumor cells and non-availability of reliable phenotype-discriminating biomarkers are stumbling blocks in the management of CaP disease. Here, we determine the role and translational relevance of ROBO1 (an organogenesis-associated gene) in human CaP. Employing CaP-progression models and prostatic tissues of Caucasian and African-American patients, we show that ROBO1 expression is localized to cell-membrane and significantly lost in primary and metastatic tumors. While Caucasians exhibited similar ROBO1 levels in primary and metastatic phenotype, a significant difference was observed between tumor phenotypes in African-Americans. Epigenetic assays identified promoter methylation of ROBO1 specific to African-American metastatic CaP cells. Using African-American CaP models for further studies, we show that ROBO1 negatively regulates motility and invasiveness of primary CaP cells, and its loss causes these cells to acquire invasive trait. To understand the underlying mechanism, we employed ROBO1-expressing/ROBO1-C2C3-mutant constructs, immunoprecipitation, confocal-microscopy and luciferase-reporter techniques. We show that ROBO1 through its interaction with DOCK1 (at SH3-SH2-domain) controls the Rac-activation. However, loss of ROBO1 results in Rac1-activation which in turn causes E-Cadherin/β-catenin cytoskeleton destabilization and induction of cell migration. We suggest that ROBO1 is a predictive biomarker that has potential to discriminate among CaP types, and could be exploited as a molecular target to inhibit the progression of disease as well as treat metastasis in high-risk populations such as African-Americans. PMID:24752651

  10. Community-acquired pneumonia.

    PubMed

    Falguera, M; Ramírez, M F

    2015-11-01

    This article not only reviews the essential aspects of community-acquired pneumonia for daily clinical practice, but also highlights the controversial issues and provides the newest available information. Community-acquired pneumonia is considered in a broad sense, without excluding certain variants that, in recent years, a number of authors have managed to delineate, such as healthcare-associated pneumonia. The latter form is nothing more than the same disease that affects more frail patients, with a greater number of risk factors, both sharing an overall common approach. PMID:26186969

  11. Cross-sector leadership development for preparedness.

    PubMed

    Potter, Margaret A; Burns, Helen K; Barron, Gerald; Grofebert, Alice; Bednarz, G Daniel

    2005-01-01

    After fall 2001, scientists and professionals recognized the importance of integrating public health with traditional first-response professions in planning and training for disasters. However, operationalizing this approach among professionals in the field confronted barriers that were both inter-cultural and jurisdictional. The Pennsylvania Preparedness Leadership Institute (PPLI) is a collaboration of the Pennsylvania Department of Health and the University of Pittsburgh Center for Public Health Preparedness. Team members are recruited from public health, emergency medicine, emergency management, hospitals, and public safety agencies from each of nine multi-county regions in Pennsylvania. Each team takes on a year-long project that addresses a strategic problem as a focus for capacity-building within its region. Unexpectedly during PPLI's first year in operation, a hepatitis-A outbreak tested whether one regional team could successfully mount the necessary integrated response. This experience, as well as the planned evaluation for PPLI, demonstrated both the successful processes and the positive impact of this integrated leadership training initiative. PMID:16025714

  12. Preparedness for AIDS vaccine trials in India.

    PubMed

    Excler, Jean-Louis; Kochhar, Sonali; Kapoor, Sushma; Das, Sweta; Bahri, Jyoti; Ghosh, Meenakshi Datta; Ganguly, N K; Nayyar, Anjali; Chataway, Mark

    2008-06-01

    India bears a heavy disease burden of HIV/AIDS infected and affected people. A safe, effective and accessible preventive AIDS vaccine, used along with other preventive interventions, is urgently needed to stem the epidemic. This review highlights the extensive preparedness activities undertaken from 2002 by the International AIDS Vaccine Initiative (IAVI), its Indian government and non government partners with the Indian scientific, political, media and community stakeholders and the capacity building process, before the conduct of the first ever AIDS vaccine trials in India in early 2005. Issues addressed included mistrust of clinical research due to past history of some unethical trials, transparency, community involvement, stigma and discrimination, provision for care and treatment of participants, informed consent, gender considerations, approval process, and operational aspects. The strong political support along with preparedness activities led to the successful conduct of AIDS vaccine trials enrolling equitably healthy women and men from all sections of society. This has paved the way for future vaccine trials in the country. PMID:18765870

  13. A Newly Developed Fluorescence Model for C2H6 v5 and Application to Cometary Spectra Acquired with NIRSPEC at Keck II

    NASA Technical Reports Server (NTRS)

    Radeva, Yana L.; Mumma, Michael J.; Villanueva, Geronimo L.; A?Hearn, Michael F.

    2011-01-01

    Accurate rotational temperatures are essential for extracting production rates for parent volatiles in comets. Two strong bands of ethane (v7 at 2985.39/cm and v5 at 2895.67/cm) are seen in infrared cometary spectra, but the Q-branches of v7 are not resolved by current instruments and cannot provide an accurate rotational temperature with current models.We developed a fluorescence model for the C2H6 v5 band that can be used to derive a rotational temperature.We applied our C2H6 5 model to high-resolution infrared spectra of the comets C/2004 Q2 Machholz and C/2000 WM1 (LINEAR), acquired with the Near-infrared Echelle Spectrograph on the Keck II telescope. We demonstrate agreement among the rotational temperatures derived from C2H6 v5 and other species, and between mixing ratios derived from C2H6 v5 and C2H6 v7. As a symmetric hydrocarbon, C2H6 is observed only in the infrared, and it is now the fifth molecule (along with H2O, HCN, CO, and H2CO) for which we can derive a reliable rotational temperature from cometary infrared spectra.

  14. Acquired Brain Injury Program.

    ERIC Educational Resources Information Center

    Schwartz, Stacey Hunter

    This paper reviews the Acquired Brain Injury (ABI) Program at Coastline Community College (California). The ABI Program is a two-year, for-credit educational curriculum designed to provide structured cognitive retraining for adults who have sustained an ABI due to traumatic (such as motor vehicle accident or fall) or non-traumatic(such as…

  15. Acquired von Willebrand disease.

    PubMed

    Petrini, P

    1999-05-01

    Acquired von Willebrand disease (AvWD) is a syndrome that has clinical and laboratory features similar to hereditary vWD. In contrast to the latter it occurs in patients without a family history of previous bleeding tendency. PMID:23401904

  16. Acquired resistance to mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models

    PubMed Central

    Eberlein, Catherine A.; Stetson, Daniel; Markovets, Aleksandra A.; Al-Kadhimi, Katherine J.; Lai, Zhongwu; Fisher, Paul R.; Meador, Catherine B.; Spitzler, Paula; Ichihara, Eiki; Ross, Sarah J.; Ahdesmaki, Miika J.; Ahmed, Ambar; Ratcliffe, Laura E.; Christey O’Brien, Elizabeth L.; Barnes, Claire H.; Brown, Henry; Smith, Paul D.; Dry, Jonathan R.; Beran, Garry; Thress, Kenneth S.; Dougherty, Brian; Pao, William; Cross, Darren A. E.

    2015-01-01

    Resistance to targeted EGFR inhibitors is likely to develop in EGFR mutant lung cancers. Early identification of innate or acquired resistance mechanisms to these agents is essential to direct development of future therapies. We describe the detection of heterogeneous mechanisms of resistance within populations of EGFR mutant cells (PC9 and/or NCI-H1975) with acquired resistance to current and newly developed EGFR TKIs including AZD9291. We report the detection of NRAS mutations, including a novel E63K mutation, and a gain of copy number of WT NRAS or WT KRAS in cell populations resistant to gefitinib, afatinib, WZ4002 or AZD9291. Compared to parental cells, a number of resistant cell populations were more sensitive to inhibition by the MEK inhibitor selumetinib (AZD6244; ARRY-142886) when treated in combination with the originating EGFR inhibitor. In vitro, a combination of AZD9291 with selumetinib prevented emergence of resistance in PC9 cells and delayed resistance in NCI-H1975 cells. In vivo, concomitant dosing of AZD9291 with selumetinib caused regression of AZD9291-resistant tumours in an EGFRm/T790M transgenic model. Our data support the use of a combination of AZD9291 with a MEK inhibitor to delay or prevent resistance to AZD9291 in EGFRm and/or EGFRm/T790M tumours. Further, these findings suggest that NRAS modifications in tumour samples from patients who have progressed on current or EGFR inhibitors in development may support subsequent treatment with a combination of EGFR and MEK inhibition. PMID:25870145

  17. Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.

    PubMed

    Eberlein, Catherine A; Stetson, Daniel; Markovets, Aleksandra A; Al-Kadhimi, Katherine J; Lai, Zhongwu; Fisher, Paul R; Meador, Catherine B; Spitzler, Paula; Ichihara, Eiki; Ross, Sarah J; Ahdesmaki, Miika J; Ahmed, Ambar; Ratcliffe, Laura E; O'Brien, Elizabeth L Christey; Barnes, Claire H; Brown, Henry; Smith, Paul D; Dry, Jonathan R; Beran, Garry; Thress, Kenneth S; Dougherty, Brian; Pao, William; Cross, Darren A E

    2015-06-15

    Resistance to targeted EGFR inhibitors is likely to develop in EGFR-mutant lung cancers. Early identification of innate or acquired resistance mechanisms to these agents is essential to direct development of future therapies. We describe the detection of heterogeneous mechanisms of resistance within populations of EGFR-mutant cells (PC9 and/or NCI-H1975) with acquired resistance to current and newly developed EGFR tyrosine kinase inhibitors, including AZD9291. We report the detection of NRAS mutations, including a novel E63K mutation, and a gain of copy number of WT NRAS or WT KRAS in cell populations resistant to gefitinib, afatinib, WZ4002, or AZD9291. Compared with parental cells, a number of resistant cell populations were more sensitive to inhibition by the MEK inhibitor selumetinib (AZD6244; ARRY-142886) when treated in combination with the originating EGFR inhibitor. In vitro, a combination of AZD9291 with selumetinib prevented emergence of resistance in PC9 cells and delayed resistance in NCI-H1975 cells. In vivo, concomitant dosing of AZD9291 with selumetinib caused regression of AZD9291-resistant tumors in an EGFRm/T790M transgenic model. Our data support the use of a combination of AZD9291 with a MEK inhibitor to delay or prevent resistance to AZD9291 in EGFRm and/or EGFRm/T790M tumors. Furthermore, these findings suggest that NRAS modifications in tumor samples from patients who have progressed on current or EGFR inhibitors in development may support subsequent treatment with a combination of EGFR and MEK inhibition. PMID:25870145

  18. 33 CFR 203.21 - Disaster preparedness responsibilities of non-Federal interests.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Disaster preparedness... DISASTER PROCEDURES Disaster Preparedness § 203.21 Disaster preparedness responsibilities of non-Federal interests. Disaster preparedness is a basic tenet of State and local responsibility. Assistance...

  19. 33 CFR 203.21 - Disaster preparedness responsibilities of non-Federal interests.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Disaster preparedness... DISASTER PROCEDURES Disaster Preparedness § 203.21 Disaster preparedness responsibilities of non-Federal interests. Disaster preparedness is a basic tenet of State and local responsibility. Assistance...

  20. 33 CFR 203.21 - Disaster preparedness responsibilities of non-Federal interests.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Disaster preparedness... DISASTER PROCEDURES Disaster Preparedness § 203.21 Disaster preparedness responsibilities of non-Federal interests. Disaster preparedness is a basic tenet of State and local responsibility. Assistance...

  1. The Common Ground Preparedness Framework: A Comprehensive Description of Public Health Emergency Preparedness

    PubMed Central

    Theadore, Fred; Jellison, James B.

    2012-01-01

    Currently, public health emergency preparedness (PHEP) is not well defined. Discussions about public health preparedness often make little progress, for lack of a shared understanding of the topic. We present a concise yet comprehensive framework describing PHEP activities. The framework, which was refined for 3 years by state and local health departments, uses terms easily recognized by the public health workforce within an information flow consistent with the National Incident Management System. To assess the framework's completeness, strengths, and weaknesses, we compare it to 4 other frameworks: the RAND Corporation's PREPARE Pandemic Influenza Quality Improvement Toolkit, the National Response Framework's Public Health and Medical Services Functional Areas, the National Health Security Strategy Capabilities List, and the Centers for Disease Control and Prevention's PHEP Capabilities. PMID:22397343

  2. The common ground preparedness framework: a comprehensive description of public health emergency preparedness.

    PubMed

    Gibson, P Joseph; Theadore, Fred; Jellison, James B

    2012-04-01

    Currently, public health emergency preparedness (PHEP) is not well defined. Discussions about public health preparedness often make little progress, for lack of a shared understanding of the topic. We present a concise yet comprehensive framework describing PHEP activities. The framework, which was refined for 3 years by state and local health departments, uses terms easily recognized by the public health workforce within an information flow consistent with the National Incident Management System. To assess the framework's completeness, strengths, and weaknesses, we compare it to 4 other frameworks: the RAND Corporation's PREPARE Pandemic Influenza Quality Improvement Toolkit, the National Response Framework's Public Health and Medical Services Functional Areas, the National Health Security Strategy Capabilities List, and the Centers for Disease Control and Prevention's PHEP Capabilities. PMID:22397343

  3. Salient beliefs about earthquake hazards and household preparedness.

    PubMed

    Becker, Julia S; Paton, Douglas; Johnston, David M; Ronan, Kevin R

    2013-09-01

    Prior research has found little or no direct link between beliefs about earthquake risk and household preparedness. Furthermore, only limited work has been conducted on how people's beliefs influence the nature and number of preparedness measures adopted. To address this gap, 48 qualitative interviews were undertaken with residents in three urban locations in New Zealand subject to seismic risk. The study aimed to identify the diverse hazard and preparedness-related beliefs people hold and to articulate how these are influenced by public education to encourage preparedness. The study also explored how beliefs and competencies at personal, social, and environmental levels interact to influence people's risk management choices. Three main categories of beliefs were found: hazard beliefs; preparedness beliefs; and personal beliefs. Several salient beliefs found previously to influence the preparedness process were confirmed by this study, including beliefs related to earthquakes being an inevitable and imminent threat, self-efficacy, outcome expectancy, personal responsibility, responsibility for others, and beliefs related to denial, fatalism, normalization bias, and optimistic bias. New salient beliefs were also identified (e.g., preparedness being a "way of life"), as well as insight into how some of these beliefs interact within the wider informational and societal context. PMID:23339741

  4. Academic-community partnerships for sustainable preparedness and response systems.

    PubMed

    Isakov, Alexander; O'Neal, Patrick; Prescott, John; Stanley, Joan; Herrmann, Jack; Dunlop, Anne

    2014-01-01

    Academic institutions possess tremendous resources that could be important for community disaster response and preparedness activities. In-depth exploration of the role of academic institutions in community disaster response has elicited information about particular academic resources leveraged for and essential to community preparedness and response; factors that contribute to the decision-making process for partner engagement; and facilitators of and barriers to sustainable collaborations from the perspectives of academic institutions, public health and emergency management agencies, and national association and agency leaders. The Academic-Community Partnership Project of the Emory University Preparedness and Emergency Response Research Center in collaboration with the Association of Schools of Public Health convened an invitational summit which included leadership from the National Association of County and City Health Officials, Association of State and Territorial Health Officials, Directors of Public Health Preparedness, Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response, CDC Office of Public Health Preparedness and Response, Association of Schools of Public Health, Association of American Medical Colleges, Association of Academic Health Centers, American Association of Colleges of Nursing, Council of State and Territorial Epidemiologists, and American Association of Poison Control Centers. From this convention, emerged recommendations for building and sustaining academic-public health-community collaborations for preparedness locally and regionally. PMID:25068939

  5. Investigating factors for disaster preparedness among residents of Kuala Lumpur

    NASA Astrophysics Data System (ADS)

    Mohammad-pajooh, E.; Aziz, K. Ab.

    2014-05-01

    The review of past researches discussed that factors such as climate change and movement toward urbanization will result in more frequent and severe disasters in the near future (Yasuhara et al., 2011). Flash flood is the most common type of disaster that residents of Kuala Lumpur (KL) come across, thus in this study, it was desired to discover the factors affecting preparedness among residents of KL as well as assessing the variation of individual preparedness among residents. With the aid of SPSS analysis, the reliability of data, correlation and regression analysis between the investigated factors and disaster preparedness were obtained. According to this research it was found that level of preparedness of residents of KL is still below average; majority of social demographic indicators such as income, education, age, and property ownership showed significant contribution to the variation of disaster preparedness among the residents. For instance men were much more prepared in comparison to women; residents with high level of income and education had also significantly higher preparedness compared to those with low level of income and education. Race was the only factor that differs from the findings of previous studies; since race does not affect the preparedness.

  6. Preparedness of orthopaedic surgeons for modern battlefield surgery.

    PubMed

    Kearney, Sean P; Bluman, Eric M; Lonergan, Keith T; Arrington, Edward D; Ficke, James R

    2012-09-01

    Over 220 U.S. Army orthopaedic surgeons have deployed during the Global War on Terrorism (GWOT). This study documents the orthopaedic procedures performed during the GWOT and identifies training that prepared surgeons for deployment. It reveals deficiencies in surgeons' preparedness and intends to improve predeployment training. All surgeons deployed during the GWOT from 2001 to 2007 were surveyed. Questions fit 4 general categories: deployment demographics, medical and surgical experiences, predeployment preparation, and self-perceived preparedness during deployment. Response rate was 70%. Surgeons averaged 138 adult operative cases and 26 pediatric cases per deployment. All surgeons performed irrigation and debridement, 94% external fixation, 93% amputations, 89% arthrotomies, 86% open reduction and internal fixation, and 76% soft-tissue coverage procedures. Residency and fellowship contributed most to surgeon preparedness for deployment. Surgeons generally reported high levels of preparedness, but nearly 1 in 6 reported low levels of medical, surgical and physical preparedness. More reported low levels of mental preparedness. Soft-tissue coverage was the most frequently reported surgical deficiency. This study documents the number and types of orthopaedic procedures performed during the GWOT and identifies the self-perceived preparedness deficiencies of surgeons in a combat environment. Improvements in predeployment training are needed to better prepare surgeons for managing battlefield causalities. PMID:23025135

  7. Molecular modeling, dynamics studies and virtual screening of Fructose 1, 6 biphosphate aldolase-II in community acquired- methicillin resistant Staphylococcus aureus (CA-MRSA).

    PubMed

    Yadav, Pramod Kumar; Singh, Gurmit; Gautam, Budhayash; Singh, Satendra; Yadav, Madhu; Srivastav, Upasana; Singh, Brijendra

    2013-01-01

    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged as a nosocomial pathogen to the community which commonly causes skin and soft-tissue infections (SSTIs). This strain (MW2) has now become resistant to the most of the beta-lactam antibiotics; therefore it is the urgent need to identify the novel drug targets. Recently fructose 1,6 biphosphate aldolase-II (FBA) has been identified as potential drug target in CA-MRSA. The FBA catalyses the retro-ketolic cleavage of fructose-1,6-bisphosphate (FBP) to yield dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P) in glycolytic pathway. In the present research work the 3D structure of FBA was predicted using the homology modeling method followed by validation. The molecular dynamics simulation (MDS) of the predicted model was carried out using the 2000 ps time scale and 1000000 steps. The MDS results suggest that the modeled structure is stable. The predicted model of FBA was used for virtual screening against the NCI diversity subset-II ligand databases which contain 1364 compounds. Based on the docking energy scores, it was found that top four ligands i.e. ZINC01690699, ZINC13154304, ZINC29590257 and ZINC29590259 were having lower energy scores which reveal higher binding affinity towards the active site of FBA. These ligands might act as potent inhibitors for the FBA so that the menace of antimicrobial resistance in CA-MRSA can be conquered. However, pharmacological studies are required to confirm the inhibitory activity of these ligands against the FBA in CA-MRSA. PMID:23423142

  8. Theoretical perspectives on public communication preparedness for terrorist attacks.

    PubMed

    Wray, Ricardo J; Kreuter, Matthew W; Jacobsen, Heather; Clements, Bruce; Evans, R Gregory

    2004-01-01

    The experience of federal health authorities in responding to the mailed anthrax attacks in the Fall of 2001 sheds light on the challenges of public information dissemination in emergencies. Lessons learned from the Fall of 2001 have guided more recent efforts related to crisis communication and preparedness goals. This article applies theories and evidence from the field of communication to provide an orientation to how public health communication can best contribute to the preparedness effort. This theoretical orientation provides a framework to systematically assess current recommendations for preparedness communication. PMID:15596970

  9. LONG-TERM EARTHQUAKE PREPAREDNESS IN CHARLESTON, SOUTH CAROLINA.

    USGS Publications Warehouse

    Gori, P.L.; Greene, M.R.

    1986-01-01

    The Charleston, South Carolina, area offers a unique opportunity to conduct studies that give insight into the implementation of policy for long-term earthquake preparedness at the local level. Research by Greene and Gori documented the low state of preparedness in 1981. Recent studies show that earthquake preparedness activities are now occurring in Charleston. Since 1981, increased national attention has been used by local citizens in Charleston to overcome political, informational, social, organizational, and economic barriers which tend to retard the adoption and implementation of earthquake mitigation policies.

  10. Emergency preparedness: school nurses leading the way.

    PubMed

    Flaherty, Elizabeth A

    2013-07-01

    Nurses are trained to think in terms of the nursing process, which encompasses the five steps of assessment, diagnosis, outcomes/planning, implementation, and evaluation. Cities and towns have developed emergency plans based on the "all-hazards" approach. School district plans are also formulated based on the all-hazards approach of hazard mitigation, preparedness, response, and recovery, which mirrors the nursing process. Individual school efforts focus on thesefourprinciples to facilitate development of a comprehensive plan for each school. Utilizing the principles of education, collaboration, resource utilization, leadership, and advocacy throughout the evolution of an updated and functional plan allows for an inclusive and adaptable plan. Like the nursing process, these steps are not separate and distinct, but a continuous process. PMID:23937000

  11. Radiological emergency: Malaysian preparedness and response.

    PubMed

    Yusof, Mohd Abd Wahab; Ali, Hamrah Mohd

    2011-07-01

    Planning and preparation in advance for radiological emergencies can help to minimise potential public health and environmental threats if and when an actual emergency occurs. During the planning process, emergency response organisations think through how they would respond to each type of incident and the resources that will be needed. In Malaysia, planning, preparation for and response to radiological emergencies involve many parties. In the event of a radiological emergency and if it is considered a disaster, the National Security Council, the Atomic Energy Licensing Board and the Malaysian Nuclear Agency (Nuclear Malaysia) will work together with other federal agencies, state and local governments, first responders and international organisations to monitor the situation, contain the release, and clean up the contaminated site. Throughout the response, these agencies use their protective action guidelines. This paper discusses Malaysian preparedness for, and response to, any potential radiological emergency. PMID:21729940

  12. Acquired von Willebrand disease.

    PubMed

    Kumar, Shaji; Pruthi, Rajiv K; Nichols, William L

    2002-02-01

    Acquired von Willebrand disease (AvWD) is a relatively rare acquired bleeding disorder that usually occurs in elderly patients, in whom its recognition may be delayed. Patients usually present predominantly with mucocutaneous bleeding, with no previous history of bleeding abnormalities and no clinically meaningful family history. Various underlying diseases have been associated with AvWD, most commonly hematoproliferative disorders, including monoclonal gammopathies, lymphoproliferative disorders, and myeloproliferative disorders. The pathogenesis of AvWD remains incompletely understood but includes autoantibodies directed against the von Willebrand factor (vWF), leading to a more rapid clearance from the circulation or interference with its function, adsorption of vWF by tumor cells, and nonimmunologic mechanisms of destruction. Laboratory evaluation usually reveals a pattern of prolonged bleeding time and decreased levels of vWF antigen, ristocetin cofactor activity, and factor VIII coagulant activity consistent with a diagnosis of vWD. Acquired vWD is distinguished from the congenital form by age at presentation, absence of a personal and family history of bleeding disorders, and, often, presence of a hematoproliferative or autoimmune disorder. The severity of the bleeding varies considerably among patients. Therapeutic options include desmopressin and certain factor VIII concentrates that also contain vWF. Successful treatment of the associated illness can reverse the clinical and laboratory manifestations. Intravenous immunoglobulins have also shown some efficacy in the management of AvWD, especially cases associated with monoclonal gammopathies. Awareness of AvWD is essential for diagnosis and appropriate management. PMID:11838652

  13. Applying behavioral science to workforce challenges in the public health emergency preparedness system.

    PubMed

    McCabe, O Lee; DiClemente, Carlo C; Links, Jonathan M

    2012-01-01

    When disasters and other broad-scale public health emergencies occur in the United States, they often reveal flaws in the pre-event preparedness of those individuals and agencies charged with responsibility for emergency response and recovery activities. A significant contributor to this problem is the unwillingness of some public health workers to participate in the requisite planning, training, and response activities to ensure quality preparedness. The thesis of this article is that there are numerous, empirically supported models of behavior change that hold potential for motivating role-appropriate behavior in public health professionals. The models that are highlighted here for consideration and prospective adaptation to the public health emergency preparedness system (PHEPS) are the Transtheoretical Model of Intentional Behavior Change (TTM) and Motivational Interviewing (MI). Core concepts in TTM and MI are described, and specific examples are offered to illustrate the relevance of the frameworks for understanding and ameliorating PHEPS-based workforce problems. Finally, the requisite steps are described to ensure the readiness of organizations to support the implementation of the ideas proposed. PMID:22916453

  14. Consequences of cell-to-cell P-glycoprotein transfer on acquired multidrug resistance in breast cancer: a cell population dynamics model

    PubMed Central

    2011-01-01

    Background Cancer is a proliferation disease affecting a genetically unstable cell population, in which molecular alterations can be somatically inherited by genetic, epigenetic or extragenetic transmission processes, leading to a cooperation of neoplastic cells within tumoural tissue. The efflux protein P-glycoprotein (P-gp) is overexpressed in many cancer cells and has known capacity to confer multidrug resistance to cytotoxic therapies. Recently, cell-to-cell P-gp transfers have been shown. Herein, we combine experimental evidence and a mathematical model to examine the consequences of an intercellular P-gp trafficking in the extragenetic transfer of multidrug resistance from resistant to sensitive cell subpopulations. Methodology and Principal Findings We report cell-to-cell transfers of functional P-gp in co-cultures of a P-gp overexpressing human breast cancer MCF-7 cell variant, selected for its resistance towards doxorubicin, with the parental sensitive cell line. We found that P-gp as well as efflux activity distribution are progressively reorganized over time in co-cultures analyzed by flow cytometry. A mathematical model based on a Boltzmann type integro-partial differential equation structured by a continuum variable corresponding to P-gp activity describes the cell populations in co-culture. The mathematical model elucidates the population elements in the experimental data, specifically, the initial proportions, the proliferative growth rates, and the transfer rates of P-gp in the sensitive and resistant subpopulations. Conclusions We confirmed cell-to-cell transfer of functional P-gp. The transfer process depends on the gradient of P-gp expression in the donor-recipient cell interactions, as they evolve over time. Extragenetically acquired drug resistance is an additional aptitude of neoplastic cells which has implications in the diagnostic value of P-gp expression and in the design of chemotherapy regimens. Reviewers This article was reviewed by

  15. A model-based approach for detection of runways and other objects in image sequences acquired using an on-board camera

    NASA Technical Reports Server (NTRS)

    Kasturi, Rangachar; Devadiga, Sadashiva; Tang, Yuan-Liang

    1994-01-01

    This research was initiated as a part of the Advanced Sensor and Imaging System Technology (ASSIST) program at NASA Langley Research Center. The primary goal of this research is the development of image analysis algorithms for the detection of runways and other objects using an on-board camera. Initial effort was concentrated on images acquired using a passive millimeter wave (PMMW) sensor. The images obtained using PMMW sensors under poor visibility conditions due to atmospheric fog are characterized by very low spatial resolution but good image contrast compared to those images obtained using sensors operating in the visible spectrum. Algorithms developed for analyzing these images using a model of the runway and other objects are described in Part 1 of this report. Experimental verification of these algorithms was limited to a sequence of images simulated from a single frame of PMMW image. Subsequent development and evaluation of algorithms was done using video image sequences. These images have better spatial and temporal resolution compared to PMMW images. Algorithms for reliable recognition of runways and accurate estimation of spatial position of stationary objects on the ground have been developed and evaluated using several image sequences. These algorithms are described in Part 2 of this report. A list of all publications resulting from this work is also included.

  16. A model-based approach for detection of runways and other objects in image sequences acquired using an on-board camera

    NASA Astrophysics Data System (ADS)

    Kasturi, Rangachar; Devadiga, Sadashiva; Tang, Yuan-Liang

    1994-08-01

    This research was initiated as a part of the Advanced Sensor and Imaging System Technology (ASSIST) program at NASA Langley Research Center. The primary goal of this research is the development of image analysis algorithms for the detection of runways and other objects using an on-board camera. Initial effort was concentrated on images acquired using a passive millimeter wave (PMMW) sensor. The images obtained using PMMW sensors under poor visibility conditions due to atmospheric fog are characterized by very low spatial resolution but good image contrast compared to those images obtained using sensors operating in the visible spectrum. Algorithms developed for analyzing these images using a model of the runway and other objects are described in Part 1 of this report. Experimental verification of these algorithms was limited to a sequence of images simulated from a single frame of PMMW image. Subsequent development and evaluation of algorithms was done using video image sequences. These images have better spatial and temporal resolution compared to PMMW images. Algorithms for reliable recognition of runways and accurate estimation of spatial position of stationary objects on the ground have been developed and evaluated using several image sequences. These algorithms are described in Part 2 of this report. A list of all publications resulting from this work is also included.

  17. Probabilistic risk assessment support of emergency preparedness at the Savannah River Site

    SciTech Connect

    O'Kula, K.R.; Baker, W.H.; Simpkins, A.A.; Taylor, R.P. ); Wagner, K.C.; Amos, C.N. )

    1992-01-01

    Integration of the Probabilistic Risk Assessment (PRA) for K Reactor operation into related technical areas at the Savannah River Site (SRS) includes coordination with several onsite organizations responsible for maintaining and upgrading emergency preparedness capabilities. Major functional categories of the PRA application are scenario development and source term algorithm enhancement. Insights and technologies from the SRS PRA have facilitated development of: (1) credible timelines for scenarios; (2) algorithms tied to plant instrumentation to provide best-estimate source terms for dose projection; and (3) expert-system logic models to implement informed counter-measures to assure onsite and offsite safety following accidental releases. The latter methodology, in particular, is readily transferable to other reactor and non-reactor facilities at SRS and represents a distinct advance relative to emergency preparedness capabilities elsewhere in the DOE complex.

  18. Probabilistic risk assessment support of emergency preparedness at the Savannah River Site

    SciTech Connect

    O`Kula, K.R.; Baker, W.H.; Simpkins, A.A.; Taylor, R.P.; Wagner, K.C.; Amos, C.N.

    1992-12-31

    Integration of the Probabilistic Risk Assessment (PRA) for K Reactor operation into related technical areas at the Savannah River Site (SRS) includes coordination with several onsite organizations responsible for maintaining and upgrading emergency preparedness capabilities. Major functional categories of the PRA application are scenario development and source term algorithm enhancement. Insights and technologies from the SRS PRA have facilitated development of: (1) credible timelines for scenarios; (2) algorithms tied to plant instrumentation to provide best-estimate source terms for dose projection; and (3) expert-system logic models to implement informed counter-measures to assure onsite and offsite safety following accidental releases. The latter methodology, in particular, is readily transferable to other reactor and non-reactor facilities at SRS and represents a distinct advance relative to emergency preparedness capabilities elsewhere in the DOE complex.

  19. Insuring against earthquakes: simulating the cost-effectiveness of disaster preparedness.

    PubMed

    de Hoop, Thomas; Ruben, Ruerd

    2010-04-01

    Ex-ante measures to improve risk preparedness for natural disasters are generally considered to be more effective than ex-post measures. Nevertheless, most resources are allocated after an event in geographical areas that are vulnerable to natural disasters. This paper analyses the cost-effectiveness of ex-ante adaptation measures in the wake of earthquakes and provides an assessment of the future role of private and public agencies in disaster risk management. The study uses a simulation model approach to evaluate consumption losses after earthquakes under different scenarios of intervention. Particular attention is given to the role of activity diversification measures in enhancing disaster preparedness and the contributions of (targeted) microcredit and education programmes for reconstruction following a disaster. Whereas the former measures are far more cost-effective, missing markets and perverse incentives tend to make ex-post measures a preferred option, thus occasioning underinvestment in ex-ante adaptation initiatives. PMID:20002709

  20. Emergency preparedness at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    SciTech Connect

    Skipper, M.N.

    1990-03-01

    Emergency preparedness for industry was commonly believed to be an essential responsibility on the part of management. Therefore, this study was conducted to research and accumulate information and data on emergency preparedness at Oak Ridge National Laboratory (ORNL). The objective of this study was to conduct a thorough evaluation of emergency preparedness knowledge among employees to determine if they were properly informed or if they needed more training. Also, this study was conducted to provide insight to management as to what their responsibility was concerning this training. To assess employee emergency preparedness knowledge, a questionnaire was developed and administered to 100 employees at ORNL. The data was analyzed using frequencies and percentages of response and was displayed through the use of graphs within the report. 22 refs., 22 figs.

  1. 78 FR 72122 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Commission (NRC) is making available for comment Emergency Preparedness Frequently Asked Question (EPFAQ) No... Library at http://www.nrc.gov/reading-rm/adams.html . To begin the search, select ``ADAMS Public...

  2. [Acquired von Willebrand syndrome].

    PubMed

    Franchini, Massimo

    2006-01-01

    Acquired von Willebrand syndrome (aVWS) is a rare, but probably underestimated, bleeding disorder that mimics the congenital form of von Willebrand disease (VWD) in terms of laboratory findings and clinical presentation. However, unlike congenital VWD, it arises in individuals with no personal or family history of bleeding. AVWS occurs in association with a variety of underlying disorders, including lymphoproliferative disorders, myeloproliferative disorders and cardiovascular diseases. The main pathogenic, clinical, laboratory and therapeutic aspects of this syndrome are concisely reported in this review. PMID:16913181

  3. Disaster preparedness: institutional capacity building in the Americas.

    PubMed

    Poncelet, J L; de Ville de Goyet, C

    1996-01-01

    Latin American and Caribbean countries are prone to natural, technological and "complex" disasters. This vulnerability to catastrophic events led the region to undertake the long journey away from an ad hoc response towards institutional preparedness and, more recently, to disaster prevention and mitigation. This article attempts to outline the definitions and basic principles of institutional emergency preparedness, including reliance on the more effective use of existing resources, rather than establishment of special stockpiles and equipment; the critical importance of general participation and awareness; and the interrelationship of the health sector with others and the potential for leadership. How to assess the level of preparedness is discussed. Stress is placed on the fact that preparedness is traditionally confused with the existence of a written disaster plan. Preparedness should be seen as a never-ending, complex process that can only be assessed through an in-depth review of coordination, planning, training and logistic elements. There is also a fundamental distinction between preparedness, i.e., "getting ready to respond" and disaster prevention/mitigation, which aims to reduce the health impact. The latter calls for the collaboration of engineers, architects, planners and economists with the health sector. It is illustrated by the regional initiative in the Americas to reduce the physical vulnerability of hospitals to earthquakes and hurricanes. In spite of the encouraging achievements, much remains to be done. Weak areas include preparedness for technological disasters, and a true inter-country preventive approach to common disasters across borders. Electronic communications through the Internet will also help to suppress borders and boundaries, contributing to a truly collective approach to emergency preparedness and disaster relief coordination. PMID:9170234

  4. The danger of declining funds: Public Health Preparedness in NYC.

    PubMed

    Marquez, Monica; Patel, Prachee; Raphael, Marisa; Morgenthau, Beth Maldin

    2009-09-01

    Since 2001, the New York City Department of Health and Mental Hygiene (NYC DOHMH) has built a strong public health preparedness foundation, made possible in large part by funding from the Public Health Emergency Preparedness (PHEP) Cooperative Agreement provided by the Centers for Disease Control and Prevention. While this funding has allowed NYC DOHMH to make great progress in areas such as all-hazards planning, risk communication, disease surveillance, and lab capacity, the erosion of federal preparedness dollars for all-hazards preparedness has the potential to reverse these gains. Since the initiation of the PHEP grant in 2002, PHEP funding has steadily declined nationwide. Specifically, the total federal allocation has decreased approximately 20%, from $862,777,000 in 2005 to $688,914,546 in 2009. With city and state budgets at an all-time low, federal funding cuts will have a significant impact on public health preparedness programs nationwide. In this time of strict budgetary constraints, the nation would be better served by strategically awarding federal preparedness funds to areas at greatest risk. The absence of risk-based funding in determining PHEP grant awards leaves the nation's highest-risk areas, like New York City, with insufficient resources to prepare for and respond to public health emergencies. This article examines the progress New York City has made and what is at stake as federal funding continues to wane. PMID:19821753

  5. Peer-mentored preparedness (PM-Prep): a new disaster preparedness program for adults living independently in the community.

    PubMed

    Eisenman, David Paul; Bazzano, Alicia; Koniak-Griffin, Deborah; Tseng, Chi-Hong; Lewis, Mary-Ann; Lamb, Kerry; Lehrer, Danise

    2014-02-01

    The authors studied a health promotion program called PM-Prep (Peer-Mentored Prep), which was designed to improve disaster preparedness among adults living independently in the community. PM-Prep consists of four 2-hour classes co-taught by a health educator and peer-mentors. Adults were randomly assigned to an experimental arm or a wait-list control arm. Earthquake safety knowledge and preparedness supplies were assessed prior to the intervention and at 1 month after the intervention (N  =  82). Adults in the experimental arm significantly increased preparedness by 19 percentage points, from 56% to 75% completed (p < .0001), and improved their knowledge by 8 percentage points, from 79% to 87% correct (p  =  .001). This is the first peer-mentored, targeted, and tailored disaster preparedness program tested with this population. PMID:24635691

  6. Preparedness and Emergency Response Research Centers: Using a Public Health Systems Approach to Improve All-Hazards Preparedness and Response

    PubMed Central

    Leinhos, Mary; Williams-Johnson, Mildred

    2014-01-01

    In 2008, at the request of the Centers for Disease Control and Prevention (CDC), the Institute of Medicine (IOM) prepared a report identifying knowledge gaps in public health systems preparedness and emergency response and recommending near-term priority research areas. In accordance with the Pandemic and All-Hazards Preparedness Act mandating new public health systems research for preparedness and emergency response, CDC provided competitive awards establishing nine Preparedness and Emergency Response Research Centers (PERRCs) in accredited U.S. schools of public health. The PERRCs conducted research in four IOM-recommended priority areas: (1) enhancing the usefulness of public health preparedness and response (PHPR) training, (2) creating and maintaining sustainable preparedness and response systems, (3) improving PHPR communications, and (4) identifying evaluation criteria and metrics to improve PHPR for all hazards. The PERRCs worked closely with state and local public health, community partners, and advisory committees to produce practice-relevant research findings. PERRC research has generated more than 130 peer-reviewed publications and nearly 80 practice and policy tools and recommendations with the potential to significantly enhance our nation's PHPR to all hazards and that highlight the need for further improvements in public health systems. PMID:25355970

  7. Preparedness for Pandemics: Does Variation Among States Affect the Nation as a Whole?

    PubMed Central

    Potter, Margaret A.; Brown, Shawn T.; Lee, Bruce Y.; Grefenstette, John; Keane, Christopher R.; Lin, Chyongchiou J.; Quinn, Sandra C.; Stebbins, Samuel; Sweeney, Patricia M.; Burke, Donald S.

    2013-01-01

    Objective Since states’ public health systems differ as to pandemic preparedness, this study explored whether such heterogeneity among states could affect the nation’s overall influenza rate. Design The CDC produced a uniform set of scores on a 100-point scale from its 2008 national evaluation of state preparedness to distribute materiel from the Strategic National Stockpile (SNS). This study used these SNS scores to represent each state’s relative preparedness to distribute influenza vaccine in a timely manner and assumed that “optimal” vaccine distribution would reach at least 35% of the state’s population within 4 weeks. The scores were used to determine the timing of vaccine distribution for each state: each 10-point decrement of score below 90 added an additional delay increment to the distribution time. Setting and Participants A large-scale agent-based computational model simulated an influenza pandemic in the U.S. population. In this synthetic population each individual or agent had an assigned household, age, workplace or school destination, daily commute, and domestic inter-city air travel patterns. Main Outcome Measures Simulations compared influenza case rates both nationally and at the state level under three scenarios: no vaccine distribution (baseline), optimal vaccine distribution in all states, and vaccine distribution time modified according to state-specific SNS score. Results Between optimal and SNS-modified scenarios, attack rates rose not only in low-scoring states but also in high-scoring states, demonstrating an inter-state spread of infections. Influenza rates were sensitive to variation of the SNS-modified scenario (delay increments of 1-day versus 5-days), but the inter-state effect remained. Conclusions The effectiveness of a response activity such as vaccine distribution could benefit from national standards and preparedness funding allocated in part to minimize inter-state disparities. PMID:22473116

  8. Continuous administration of bevacizumab plus capecitabine, even after acquired resistance to bevacizumab, restored anti-angiogenic and antitumor effect in a human colorectal cancer xenograft model.

    PubMed

    Iwai, Toshiki; Sugimoto, MasamichI; Harada, Suguru; Yorozu, Keigo; Kurasawa, Mitsue; Yamamoto, Kaname

    2016-08-01

    Vascular endothelial growth factor (VEGF)-neutralizing therapy with bevacizumab has become increasingly important for treating colorectal cancer. It was demonstrated that second-line chemotherapy together with bevacizumab after disease progression (PD) on first-line therapy including bevacizumab showed clinical benefits in metastatic colorectal and breast cancers (ML18147 trial, TANIA trial). One of the rationales for these trials was that the refractoriness to first-line therapy is caused by resistance to not so much bevacizumab as to the chemotherapeutic agents. Nevertheless, resistance to bevacizumab cannot be ruled out because VEGF-independent angiogenesis has been reported to be a mechanism of resistance to anti-VEGF therapy. In this study, we used a xenograft model with the human colon cancer HT-29 cells to investigate the mechanisms underlying the effect of continued administration of bevacizumab plus capecitabine even after resistance to bevacizumab was acquired. The combination of capecitabine plus bevacizumab exhibited significantly stronger antitumor and anti-angiogenic activities than did monotherapy with either agent. Capecitabine treatment significantly increased the intratumoral VEGF level compared with the control group; however, the combination with bevacizumab neutralized the VEGF. Among angiogenic factors other than VEGF, intratumoral galectin-3, which reportedly promotes angiogenesis both dependent on, and independently of VEGF, was significantly decreased in the capecitabine group and the combination group compared with the control group. In an in vitro experiment, 5-fluorouracil (5-FU), an active metabolite of capecitabine, inhibited galectin-3 production by HT-29 cells. These results suggested that capecitabine has a dual mode of action: namely, inhibition of tumor cell growth and inhibition of galectin-3 production by tumor cells. Thus, capecitabine and bevacizumab may work in a mutually complementary manner in tumor angiogenesis inhibition

  9. Continuous administration of bevacizumab plus capecitabine, even after acquired resistance to bevacizumab, restored anti-angiogenic and antitumor effect in a human colorectal cancer xenograft model

    PubMed Central

    Iwai, Toshiki; Sugimoto, Masamichi; Harada, Suguru; Yorozu, Keigo; Kurasawa, Mitsue; Yamamoto, Kaname

    2016-01-01

    Vascular endothelial growth factor (VEGF)-neutralizing therapy with bevacizumab has become increasingly important for treating colorectal cancer. It was demonstrated that second-line chemotherapy together with bevacizumab after disease progression (PD) on first-line therapy including bevacizumab showed clinical benefits in metastatic colorectal and breast cancers (ML18147 trial, TANIA trial). One of the rationales for these trials was that the refractoriness to first-line therapy is caused by resistance to not so much bevacizumab as to the chemotherapeutic agents. Nevertheless, resistance to bevacizumab cannot be ruled out because VEGF-independent angiogenesis has been reported to be a mechanism of resistance to anti-VEGF therapy. In this study, we used a xenograft model with the human colon cancer HT-29 cells to investigate the mechanisms underlying the effect of continued administration of bevacizumab plus capecitabine even after resistance to bevacizumab was acquired. The combination of capecitabine plus bevacizumab exhibited significantly stronger antitumor and anti-angiogenic activities than did monotherapy with either agent. Capecitabine treatment significantly increased the intratumoral VEGF level compared with the control group; however, the combination with bevacizumab neutralized the VEGF. Among angiogenic factors other than VEGF, intratumoral galectin-3, which reportedly promotes angiogenesis both dependent on, and independently of VEGF, was significantly decreased in the capecitabine group and the combination group compared with the control group. In an in vitro experiment, 5-fluorouracil (5-FU), an active metabolite of capecitabine, inhibited galectin-3 production by HT-29 cells. These results suggested that capecitabine has a dual mode of action: namely, inhibition of tumor cell growth and inhibition of galectin-3 production by tumor cells. Thus, capecitabine and bevacizumab may work in a mutually complementary manner in tumor angiogenesis inhibition

  10. AIDS: acquired immunodeficiency syndrome *

    PubMed Central

    Gilmore, N.J.; Beaulieu, R.; Steben, M.; Laverdière, M.

    1992-01-01

    Acquired immunodeficiency syndrome, or AIDS, is a new illness that occurs in previously healthy individuals. It is characterized by immunodeficiency, opportunistic infections and unusual malignant diseases. Life-threatening single or multiple infections with viruses, mycobacteria, fungi or protozoa are common. A rare neoplasm, Kaposi's sarcoma, has developed in approximately one third of patients with AIDS. More than 800 cases of AIDS have been reported in North America, over 24 of them in Canada. The majority of patients are male homosexuals, although AIDS has also developed in abusers of intravenously administered drugs, Haitian immigrants, individuals with hemophilia, recipients of blood transfusions, prostitutes, and infants, spouses and partners of patients with AIDS. The cause of AIDS is unknown, but the features are consistent with an infectious process. Early diagnosis can be difficult owing to the nonspecific symptoms and signs of the infections and malignant diseases. Therefore, vigilance by physicians is of the utmost importance. PMID:1544049

  11. Community-acquired pneumonia.

    PubMed

    Polverino, E; Torres Marti, A

    2011-02-01

    Despite the remarkable advances in antibiotic therapies, diagnostic tools, prevention campaigns and intensive care, community-acquired pneumonia (CAP) is still among the primary causes of death worldwide, and there have been no significant changes in mortality in the last decades. The clinical and economic burden of CAP makes it a major public health problem, particularly for children and the elderly. This issue provides a clinical overview of CAP, focusing on epidemiology, economic burden, diagnosis, risk stratification, treatment, clinical management, and prevention. Particular attention is given to some aspects related to the clinical management of CAP, such as the microbial etiology and the available tools to achieve it, the usefulness of new and old biomarkers, and antimicrobial and other non-antibiotic adjunctive therapies. Possible scenarios in which pneumonia does not respond to treatment are also analyzed to improve clinical outcomes of CAP. PMID:21242952

  12. Acquired Porphyria Cutanea Tarda

    PubMed Central

    Koval, Andrew; Danby, C. W. E.; Petermann, H.

    1965-01-01

    Currently, the porphyrias are classified in four main groups: congenital porphyria, acute intermittent porphyria, porphyria cutanea tarda hereditaria, and porphyria cutanea tarda symptomatica. The acquired form of porphyria (porphyria cutanea tarda symptomatica) occurs in older males and is nearly always associated with chronic alcoholism and hepatic cirrhosis. The main clinical changes are dermatological, with excessive skin fragility and photosensitivity resulting in erosions and bullae. Biochemically, high levels of uroporphyrin are found in the urine and stools. Treatment to date has been symptomatic and usually unsuccessful. A case of porphyria cutanea tarda symptomatica is presented showing dramatic improvement of both the skin lesions and porphyrin levels in urine and blood following repeated phlebotomy. Possible mechanisms of action of phlebotomy on porphyria cutanea tarda symptomatica are discussed. ImagesFig. 1Fig. 2 PMID:14341652

  13. [ICU acquired neuromyopathy].

    PubMed

    Gueret, G; Guillouet, M; Vermeersch, V; Guillard, E; Talarmin, H; Nguyen, B-V; Rannou, F; Giroux-Metges, M-A; Pennec, J-P; Ozier, Y

    2013-09-01

    ICU acquired neuromyopathy (IANM) is the most frequent neurological pathology observed in ICU. Nerve and muscle defects are merged with neuromuscular junction abnormalities. Its physiopathology is complex. The aim is probably the redistribution of nutriments and metabolism towards defense against sepsis. The main risk factors are sepsis, its severity and its duration of evolution. IANM is usually diagnosed in view of difficulties in weaning from mechanical ventilation, but electrophysiology may allow an earlier diagnosis. There is no curative therapy, but early treatment of sepsis, glycemic control as well as early physiotherapy may decrease its incidence. The outcomes of IANM are an increase in morbi-mortality and possibly long-lasting neuromuscular abnormalities as far as tetraplegia. PMID:23958176

  14. Forecasting disease risk for increased epidemic preparedness in public health

    NASA Technical Reports Server (NTRS)

    Myers, M. F.; Rogers, D. J.; Cox, J.; Flahault, A.; Hay, S. I.

    2000-01-01

    Emerging infectious diseases pose a growing threat to human populations. Many of the world's epidemic diseases (particularly those transmitted by intermediate hosts) are known to be highly sensitive to long-term changes in climate and short-term fluctuations in the weather. The application of environmental data to the study of disease offers the capability to demonstrate vector-environment relationships and potentially forecast the risk of disease outbreaks or epidemics. Accurate disease forecasting models would markedly improve epidemic prevention and control capabilities. This chapter examines the potential for epidemic forecasting and discusses the issues associated with the development of global networks for surveillance and prediction. Existing global systems for epidemic preparedness focus on disease surveillance using either expert knowledge or statistical modelling of disease activity and thresholds to identify times and areas of risk. Predictive health information systems would use monitored environmental variables, linked to a disease system, to be observed and provide prior information of outbreaks. The components and varieties of forecasting systems are discussed with selected examples, along with issues relating to further development.

  15. Forecasting Disease Risk for Increased Epidemic Preparedness in Public Health

    PubMed Central

    Myers, M.F.; Rogers, D.J.; Cox, J.; Flahault, A.; Hay, S.I.

    2011-01-01

    Emerging infectious diseases pose a growing threat to human populations. Many of the world’s epidemic diseases (particularly those transmitted by intermediate hosts) are known to be highly sensitive to long-term changes in climate and short-term fluctuations in the weather. The application of environmental data to the study of disease offers the capability to demonstrate vector–environment relationships and potentially forecast the risk of disease outbreaks or epidemics. Accurate disease forecasting models would markedly improve epidemic prevention and control capabilities. This chapter examines the potential for epidemic forecasting and discusses the issues associated with the development of global networks for surveillance and prediction. Existing global systems for epidemic preparedness focus on disease surveillance using either expert knowledge or statistical modelling of disease activity and thresholds to identify times and areas of risk. Predictive health information systems would use monitored environmental variables, linked to a disease system, to be observed and provide prior information of outbreaks. The components and varieties of forecasting systems are discussed with selected examples, along with issues relating to further development. PMID:10997211

  16. Risk management of international trade: emergency preparedness.

    PubMed

    Torres, A; David, M J; Bowman, Q P

    2002-12-01

    Emergency preparedness and management are among the most important and critical issues facing animal health in the world today. The goals of a country for an animal health emergency management (AHEM) system should include the following: --being prepared to detect and manage an outbreak of a foreign animal disease --preventing the introduction of foreign and emerging animal pathogens --having an appropriate response system for control and eradication of the disease --having a system for recovery from animal health emergencies, including natural disasters. An AHEM system can no longer be limited to a single organisation within a country. In the event of a serious threat to the animal agriculture of a country, broader and more comprehensive participation is required. If not properly planned for, animal health emergencies can rapidly become national disasters. Therefore, it is essential that the central government of a country work towards these goals through partnerships with other Federal and State/Provincial/District organisations, academic institutions and national animal industries. PMID:12523689

  17. Emergency Nurses’ Requirements for Disaster Preparedness

    PubMed Central

    Seyedin, Hesam; Abbasi Dolatabadi, Zahra; Rajabifard, Fatemeh

    2015-01-01

    Background: Natural and man-made disasters affect people, communities, and health systems. Nurses play a key role in the health system and must be prepared for appropriate response in disasters. Objectives: This study was done to assess the current knowledge of nurses in emergency departments for disaster preparedness. Patients and Methods: This cross-sectional study was conducted on 110 emergency nurses working in teaching hospitals affiliated to Iran University of Medical Sciences, Tehran, Iran. A questionnaire was used to collect data and the data were then analyzed using descriptive and inferential statistics with SPSS software version 16.0. Results: Based on the findings, most of the participants (64.5%) were aged 30 - 39 years old. 84% of the cases were female and 97.3% had a bachelor’s degree. The average perceived knowledge of nurses was 2.43 ± 1.01. The nurses had the highest familiarity with triage and lowest knowledge in epidemiology and decision-making. Conclusions: Lack knowledge of nurses regarding response to disaster situations indicates inefficiencies in the current system. Therefore, it is recommended to organize more workshops, annual training courses, and maneuvers based on staff needs and formulate continuous education courses for nurses. PMID:26839868

  18. InaSAFE applications in disaster preparedness

    NASA Astrophysics Data System (ADS)

    Pranantyo, Ignatius Ryan; Fadmastuti, Mahardika; Chandra, Fredy

    2015-04-01

    Disaster preparedness activities aim to reduce the impact of disasters by being better prepared to respond when a disaster occurs. In order to better anticipate requirements during a disaster, contingency planning activities can be undertaken prior to a disaster based on a realistic disaster scenario. InaSAFE is a tool that can inform this process. InaSAFE is a free and open source software that estimates the impact to people and infrastructure from potential hazard scenarios. By using InaSAFE, disaster managers can develop scenarios of disaster impacts (people and infrastructures affected) to inform their contingency plan and emergency response operation plan. While InaSAFE provides the software framework exposure data and hazard data are needed as inputs to run this software. Then InaSAFE can be used to forecast the impact of the hazard scenario to the exposure data. InaSAFE outputs include estimates of the number of people, buildings and roads are affected, list of minimum needs (rice and clean water), and response checklist. InaSAFE is developed by Indonesia's National Disaster Management Agency (BNPB) and the Australian Government, through the Australia-Indonesia Facility for Disaster Reduction (AIFDR), in partnership with the World Bank - Global Facility for Disaster Reduction and Recovery (GFDRR). This software has been used in many parts of Indonesia, including Padang, Maumere, Jakarta, and Slamet Mountain for emergency response and contingency planning.

  19. Situational awareness in public health preparedness settings

    NASA Astrophysics Data System (ADS)

    Mirhaji, Parsa; Michea, Yanko F.; Zhang, Jiajie; Casscells, Samuel W.

    2005-05-01

    September 11 2001 attacks and following Anthrax mailings introduced emergent need for developing technologies that can distinguish between man made and natural incidents in the public health level. With this objective in mind, government agencies started a funding effort to foster the design, development and implementation of such systems on a wide scale. But the outcomes have not met the expectations set by the resources invested. Multiple elements explain this phenomenon: As it has been frequent with technology, introduction of new surveillance systems to the workflow equation has occurred without taking into consideration the need for understanding and inclusion of deeper personal, psychosocial, organizational and methodological concepts. The environment, in which these systems are operating, is complex, highly dynamic, uncertain, risky, and subject to intense time pressures. Such 'difficult' environments are very challenging to the human as a decision maker. In this paper we will challenge these systems from the perspective of human factors design. We will propose employment of systematic situational awareness research for design and implementation of the next generation public health preparedness infrastructures. We believe that systems designed based on results of such analytical definition of the domain enable public health practitioners to effectively collect the most important cues from the environment, process, interpret and understand the information in the context of organizational objectives and immediate tasks at hand, and use that understanding to forecast the short term and long term impact of the events in the safety and well being of the community.

  20. MERS coronavirus: data gaps for laboratory preparedness.

    PubMed

    de Sousa, Rita; Reusken, Chantal; Koopmans, Marion

    2014-01-01

    Since the emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in 2012, many questions remain on modes of transmission and sources of virus. In outbreak situations, especially with emerging organisms causing severe human disease, it is important to understand the full spectrum of disease, and shedding kinetics in relation to infectivity and the ability to transmit the microorganism. Laboratory response capacity during the early stages of an outbreak focuses on development of virological and immunological methods for patient diagnosis, for contact tracing, and for epidemiological studies into sources, modes of transmission, identification of risk groups, and animal reservoirs. However, optimal use of this core public health laboratory capacity requires a fundamental understanding of kinetics of viral shedding and antibody response, of assay validation and of interpretation of test outcomes. We reviewed available data from MERS-CoV case reports, and compared this with data on kinetics of shedding and immune response from published literature on other human coronaviruses (hCoVs). We identify and discuss important data gaps, and biases that limit the laboratory preparedness to this novel disease. Public health management will benefit from standardised reporting of methods used, details of test outcomes by sample type, sampling date, in relation to symptoms and risk factors, along with the currently reported demographic, clinical and epidemiological findings. PMID:24286807

  1. The "Zurich E-Learning Certificate": A Role Model for the Acquirement of eCompetence for Academic Staff and an Example of a Practical Implementation

    ERIC Educational Resources Information Center

    Volk, Benno; Keller, Stefan Andreas

    2010-01-01

    Since 2002 the "Zurich E-Learning Certificate" offers lecturers and academic staff from the three main universities in Zurich the possibility to take part in a professional development program which supports the acquirement of eCompetence. The program is the result of a cooperation between the University of Zurich (UZH), the Swiss Federal…

  2. Progress of vaccine and drug development for Ebola preparedness

    PubMed Central

    2015-01-01

    Since the first case of Ebola virus disease (EVD) in Guinea was reported in March 2014 by World Health Organization (WHO), the outbreak has continued through the year and the total number of 19,065 patients was reported as the confirmed or suspected in the EVD-affected countries. Among the cases, 7,388 patients were reported death by 19 December. Currently, available therapeutics to treat the infected patients or vaccines to prevent people from infection is not developed yet while viral diagnostic methods were already developed and firmly established in a lot of countries as a first step for the preparedness of Ebola outbreak. Some potential therapeutic materials including ZMapp were supplied and the treated people got over the EVD. Several candidates of vaccines also were investigated their efficacy in animal models by National Institute of Health (NIH) and Department of Defense, and they are processing of clinical tests in West Africa aiming to finish the development by the 2015. Vaccine and therapeutic development is essential to stop the EVD outbreak in West Africa, also to protect the world from the risk which can be generated by potential spread of Ebola virus. PMID:25648233

  3. Perceived coping & concern predict terrorism preparedness in Australia

    PubMed Central

    2012-01-01

    Background In the aftermath of major terrorist incidents research shows population shifts towards protective behaviours, including specific preparedness and avoidance responses. Less is known about individual preparedness in populations with high assumed threat but limited direct exposure, such as Australia. In this study we aimed to determine whether individuals with high perceived coping and higher concern would show greater preparedness to respond to terrorism threats. Methods Adults in New South Wales (NSW) completed terrorism perception and response questions as part of computer assisted telephone interviews (CATI) in 2010 (N=2038). Responses were weighted against the NSW population. Multiple logistic regression analyses were conducted to evaluate the relationship between personal coping/concern factors and terrorism-related preparedness and avoidance behaviours, and to control for potential confounders such as socio-demographic and threat perception factors. Results Increased vigilance for suspicious behaviours was the most commonly reported behavioural response to perceived terrorism threat. Multivariate analyses showed that the factor combination of high perceived coping and higher concern was the most consistent predictor of terrorism preparedness behaviours and evacuation intentions, including increased vigilance (Adjusted Odd Ratios (AOR)=2.07, p=0.001) learning evacuation plans (AOR=1.61, p=0.05), establishing emergency contact plans (AOR=2.73, p<0.001), willingness to evacuate homes (AOR=2.20, p=0.039), and willingness to evacuate workplaces or public facilities (AOR=6.19, p=0.015) during potential future incidents. Conclusion The findings of this study suggest that terrorism preparedness behaviours are strongly associated with perceived high coping but that this relationship is also mediated by personal concerns relating to this threat. Cognitive variables such as coping self-efficacy are increasingly targeted as part of natural hazard preparedness

  4. Radiation protection issues on preparedness and response for a severe nuclear accident: experiences of the Fukushima accident.

    PubMed

    Homma, T; Takahara, S; Kimura, M; Kinase, S

    2015-06-01

    Radiation protection issues on preparedness and response for a severe nuclear accident are discussed in this paper based on the experiences following the accident at Fukushima Daiichi nuclear power plant. The criteria for use in nuclear emergencies in the Japanese emergency preparedness guide were based on the recommendations of International Commission of Radiological Protection (ICRP) Publications 60 and 63. Although the decision-making process for implementing protective actions relied heavily on computer-based predictive models prior to the accident, urgent protective actions, such as evacuation and sheltering, were implemented effectively based on the plant conditions. As there were no recommendations and criteria for long-term protective actions in the emergency preparedness guide, the recommendations of ICRP Publications 103, 109, and 111 were taken into consideration in determining the temporary relocation of inhabitants of heavily contaminated areas. These recommendations were very useful in deciding the emergency protective actions to take in the early stages of the Fukushima accident. However, some suggestions have been made for improving emergency preparedness and response in the early stages of a severe nuclear accident. PMID:25915551

  5. Developing a consensus framework and risk profile for agents of opportunity in academic medical centers: implications for public health preparedness.

    PubMed

    Farmer, Brenna M; Nelson, Lewis S; Graham, Margaret E; Bendzans, Carly; McCrillis, Aileen M; Portelli, Ian; Zhang, Meng; Goldberg, Judith; Rosenberg, Sheldon D; Goldfrank, Lewis R; Tunik, Michael

    2010-12-01

    Agents of opportunity (AO) in academic medical centers (AMC) are defined as unregulated or lightly regulated substances used for medical research or patient care that can be used as "dual purpose" substances by terrorists to inflict damage upon populations. Most of these agents are used routinely throughout AMC either during research or for general clinical practice. To date, the lack of careful regulations for AOs creates uncertain security conditions and increased malicious potential. Using a consensus-based approach, we collected information and opinions from staff working in an AMC and 4 AMC-affiliated hospitals concerning identification of AO, AO attributes, and AMC risk and preparedness, focusing on AO security and dissemination mechanisms and likely hospital response. The goal was to develop a risk profile and framework for AO in the institution. Agents of opportunity in 4 classes were identified and an AO profile was developed, comprising 16 attributes denoting information critical to preparedness for AO misuse. Agents of opportunity found in AMC present a unique and vital gap in public health preparedness. Findings of this project may provide a foundation for a discussion and consensus efforts to determine a nationally accepted risk profile framework for AO. This foundation may further lead to the implementation of appropriate regulatory policies to improve public health preparedness. Agents of opportunity modeling of dissemination properties should be developed to better predict AO risk. PMID:21149234

  6. Emerging and exotic zoonotic disease preparedness and response in the United States - coordination of the animal health component.

    PubMed

    Levings, Randall L

    2012-09-01

    For the response to a zoonotic disease outbreak to be effective, animal health authorities and disease specialists must be involved. Animal health measures are commonly directed at known diseases that threaten the health of animals and impact owners. The measures have long been applied to zoonotic diseases, including tuberculosis and brucellosis, and can be applied to emerging diseases. One Health (veterinary, public, wildlife and environmental health) and all-hazards preparedness work have done much to aid interdisciplinary understanding and planning for zoonotic diseases, although further improvements are needed. Actions along the prevention, preparedness, response and recovery continuum should be considered. Prevention of outbreaks consists largely of import controls on animals and animal products and biosecurity. Preparedness includes situational awareness, research, tool acquisition, modelling, training and exercises, animal movement traceability and policy development. Response would include detection systems and specialized personnel, institutions, authorities, strategies, methods and tools, including movement control, depopulation and vaccination if available and appropriate. The specialized elements would be applied within a general (nationally standardized) system of response. Recovery steps begin with continuity of business measures during the response and are intended to restore pre-event conditions. The surveillance for novel influenza A viruses in swine and humans and the preparedness for and response to the recent influenza pandemic illustrate the cooperation possible between the animal and public health communities. PMID:22958252

  7. Ebola preparedness in the Western Pacific Region, 2014

    PubMed Central

    Pavlin, Boris; Squires, Raynal C.; Chinnayah, Thilaka; Konings, Frank; Lee, Chin-Kei; Ailan, Li

    2015-01-01

    West Africa is currently experiencing the largest outbreak of Ebola virus disease (EVD) in history with intense transmission in several affected countries. For non-affected countries, the best protective measures are adequate levels of preparedness including vigilant surveillance to detect cases early and well prepared health systems to ensure rapid containment of the virus and to avoid further spread. The World Health Organization Regional Office for the Western Pacific recently conducted two activities: a web-based EVD preparedness survey and an EVD simulation exercise to determine the overall level of EVD preparedness in the Region. The survey and exercise together demonstrate there is a good overall level of preparedness for a potential imported case of EVD in the Western Pacific Region. However, several areas still require further strengthening before the Region can efficiently and effectively respond to potential EVD events, including laboratory testing arrangements; clinical management and infection prevention and control; and public health intervention measures, particularly at points of entry. Importantly, the survey and exercise also highlight the unique situation in Pacific island countries and emphasize that special considerations are needed to better support these countries in EVD preparedness. PMID:25960926

  8. Disaster preparedness: an investigation on motivation and barriers.

    PubMed

    Dorasamy, Magiswary; Raman, Murali; Marimuthu, Maran; Kaliannan, Maniam

    2013-01-01

    This article presents a preliminary investigation on the motivations for and the barriers that hinder preparedness toward disasters in a community. Survey questionnaires were distributed to local individuals in the nine districts of Selangor state in Malaysia. A total of 402 usable questionnaires were analyzed. The initial findings revealed that community members are motivated for disaster preparedness mainly for family safety reason. However, generally they do not know how to be prepared. This article concludes by highlighting the importance of knowledge and information in community preparedness. This research is limited to one state in Malaysia. However, the chosen state has a large effect on the Malaysian gross domestic product; hence, lack of preparedness poses a critical risk to its large population. This study on motivation and barriers for disaster preparedness is intended to increase the effectiveness of community readiness as a whole toward major disasters such as landslide and flood. The result of this study is valuable to the scientific community within the disaster management domain, the government agencies for policy and strategy formulations, and the local community to preempt, deal with, and ultimately survive disasters. This research aims to ensure that the community is continuously prepared and able to meet the evolving needs of the individual citizen as the nation strives toward promoting a knowledgeable society. PMID:24623112

  9. Ebola preparedness in the Western Pacific Region, 2014.

    PubMed

    Zhen, Xu; Pavlin, Boris; Squires, Raynal C; Chinnayah, Thilaka; Konings, Frank; Lee, Chin-Kei; Ailan, Li

    2015-01-01

    West Africa is currently experiencing the largest outbreak of Ebola virus disease (EVD) in history with intense transmission in several affected countries. For non-affected countries, the best protective measures are adequate levels of preparedness including vigilant surveillance to detect cases early and well prepared health systems to ensure rapid containment of the virus and to avoid further spread. The World Health Organization Regional Office for the Western Pacific recently conducted two activities: a web-based EVD preparedness survey and an EVD simulation exercise to determine the overall level of EVD preparedness in the Region. The survey and exercise together demonstrate there is a good overall level of preparedness for a potential imported case of EVD in the Western Pacific Region. However, several areas still require further strengthening before the Region can efficiently and effectively respond to potential EVD events, including laboratory testing arrangements; clinical management and infection prevention and control; and public health intervention measures, particularly at points of entry. Importantly, the survey and exercise also highlight the unique situation in Pacific island countries and emphasize that special considerations are needed to better support these countries in EVD preparedness. PMID:25960926

  10. Evaluation of a Tabletop Emergency Preparedness Exercise for Pharmacy Students.

    PubMed

    Pate, Adam; Bratberg, Jeffrey P; Robertson, Courtney; Smith, Gregory

    2016-04-25

    Objective. To describe the implementation and effect of an emergency preparedness laboratory activity on student knowledge, willingness to participate in emergency preparedness training, current level of preparedness, and the importance of a pharmacist's role in disaster response. Design. Second-year pharmacy students in the infectious disease module participated in a laboratory activity based on a basic disaster response tabletop exercise format. Three case-based scenarios involving infectious diseases were created by participating faculty members. Assessment. Surveys before and after the laboratory were used to assess the activity's effect on student knowledge, willingness to participate in emergency preparedness training, current level of preparedness, and the importance of a pharmacist's role in disaster response. In addition, the postsurvey assessed student perceptions of the activity's success at accomplishing faculty-specified outcomes from Appendix B of the Accreditation Council for Pharmacy Education's (ACPE) Standards. Conclusion. Implementation of an emergency response laboratory activity may improve overall students' knowledge of, confidence in, and understanding of their role as pharmacists in an emergency response, while incorporating a variety of skills and knowledge outcomes. PMID:27170821

  11. Evaluation of a Tabletop Emergency Preparedness Exercise for Pharmacy Students

    PubMed Central

    Bratberg, Jeffrey P.; Robertson, Courtney; Smith, Gregory

    2016-01-01

    Objective. To describe the implementation and effect of an emergency preparedness laboratory activity on student knowledge, willingness to participate in emergency preparedness training, current level of preparedness, and the importance of a pharmacist’s role in disaster response. Design. Second-year pharmacy students in the infectious disease module participated in a laboratory activity based on a basic disaster response tabletop exercise format. Three case-based scenarios involving infectious diseases were created by participating faculty members. Assessment. Surveys before and after the laboratory were used to assess the activity’s effect on student knowledge, willingness to participate in emergency preparedness training, current level of preparedness, and the importance of a pharmacist’s role in disaster response. In addition, the postsurvey assessed student perceptions of the activity’s success at accomplishing faculty-specified outcomes from Appendix B of the Accreditation Council for Pharmacy Education’s (ACPE) Standards. Conclusion. Implementation of an emergency response laboratory activity may improve overall students’ knowledge of, confidence in, and understanding of their role as pharmacists in an emergency response, while incorporating a variety of skills and knowledge outcomes. PMID:27170821

  12. Financial burden of emergency preparedness on an urban, academic hospital.

    PubMed

    Petinaux, Bruno

    2009-01-01

    This study assessed the direct human resource costs of a hospital's emergency preparedness planning (in 2005) by surveying participants retrospectively. Forty participants (74% of the identified population) were surveyed. Using the self-reported hourly salary of the participant, a direct salary cost was calculated for each participant. The population was 40% male and 60% female; 65% had a graduate degree or higher; 65% were administrators; 35% were clinicians; and 50% reported that their job description included a reference to emergency planning activities. All participants spent a combined total of 3,654.25 hours on emergency preparedness activities, including 20.1% on personal education/training; 11.6% on educating other people; 39.3% on paperwork or equipment maintenance; 22.2% on attendance at meetings; 5.6% on drill participation; and <1% on other activities. Considering the participants' hourly salary, direct personal costs spent on emergency preparedness activities at the institution totaled US$232,417.Ten percent, all of whom were physicians, reported no compensation for their emergency preparedness efforts at the hospital level. As much as these results illustrate the strong commitment of the institution to its community, they represent a heavy burden in light of the often unfunded mandate of emergency preparedness planning that a hospital may incur. Such responsibility is carried to some extent by all hospitals. PMID:20066636

  13. Design of the national health security preparedness index.

    PubMed

    Uzun Jacobson, Evin; Inglesby, Tom; Khan, Ali S; Rajotte, James C; Burhans, Robert L; Slemp, Catherine C; Links, Jonathan M

    2014-01-01

    The importance of health security in the United States has been highlighted by recent emergencies such as the H1N1 influenza pandemic, Superstorm Sandy, and the Boston Marathon bombing. The nation's health security remains a high priority today, with federal, state, territorial, tribal, and local governments, as well as nongovernment organizations and the private sector, engaging in activities that prevent, protect, mitigate, respond to, and recover from health threats. The Association of State and Territorial Health Officials (ASTHO), through a cooperative agreement with the Centers for Disease Control and Prevention (CDC) Office of Public Health Preparedness and Response (OPHPR), led an effort to create an annual measure of health security preparedness at the national level. The collaborative released the National Health Security Preparedness Index (NHSPI(™)) in December 2013 and provided composite results for the 50 states and for the nation as a whole. The Index results represent current levels of health security preparedness in a consistent format and provide actionable information to drive decision making for continuous improvement of the nation's health security. The overall 2013 National Index result was 7.2 on the reported base-10 scale, with areas of greater strength in the domains of health surveillance, incident and information management, and countermeasure management. The strength of the Index relies on the interdependencies of the many elements in health security preparedness, making the sum greater than its parts. Moving forward, additional health security-related disciplines and measures will be included alongside continued validation efforts. PMID:24896305

  14. Near-misses and future disaster preparedness.

    PubMed

    Dillon, Robin L; Tinsley, Catherine H; Burns, William J

    2014-10-01

    Disasters garner attention when they occur, and organizations commonly extract valuable lessons from visible failures, adopting new behaviors in response. For example, the United States saw numerous security policy changes following the September 11 terrorist attacks and emergency management and shelter policy changes following Hurricane Katrina. But what about those events that occur that fall short of disaster? Research that examines prior hazard experience shows that this experience can be a mixed blessing. Prior experience can stimulate protective measures, but sometimes prior experience can deceive people into feeling an unwarranted sense of safety. This research focuses on how people interpret near-miss experiences. We demonstrate that when near-misses are interpreted as disasters that did not occur and thus provide the perception that the system is resilient to the hazard, people illegitimately underestimate the danger of subsequent hazardous situations and make riskier decisions. On the other hand, if near-misses can be recognized and interpreted as disasters that almost happened and thus provide the perception that the system is vulnerable to the hazard, this will counter the basic "near-miss" effect and encourage mitigation. In this article, we use these distinctions between resilient and vulnerable near-misses to examine how people come to define an event as either a resilient or vulnerable near-miss, as well as how this interpretation influences their perceptions of risk and their future preparedness behavior. Our contribution is in highlighting the critical role that people's interpretation of the prior experience has on their subsequent behavior and in measuring what shapes this interpretation. PMID:24773610

  15. Promoting public health legal preparedness for emergencies: review of current trends and their relevance in light of the Ebola crisis

    PubMed Central

    Cohen, Odeya; Feder-Bubis, Paula; Bar-Dayan, Yaron; Adini, Bruria

    2015-01-01

    Background Public health legal preparedness (PHLP) for emergencies is a core component of the health system response. However, the implementation of health legal preparedness differs between low- and middle-income countries (LMIC) and developed countries. Objective This paper examines recent trends regarding public health legal preparedness for emergencies and discusses its role in the recent Ebola outbreak. Design A rigorous literature review was conducted using eight electronic databases as well as Google Scholar. The results encompassed peer-reviewed English articles, reports, theses, and position papers dating from 2011 to 2014. Earlier articles concerning regulatory actions were also examined. Results The importance of PHLP has grown during the past decade and focuses mainly on infection–disease scenarios. Amid LMICs, it mostly refers to application of international regulations, whereas in developed states, it focuses on independent legislation and creation of conditions optimal to promoting an effective emergency management. Among developed countries, the United States’ utilisation of health legal preparedness is the most advanced, including the creation of a model comprising four elements: law, competencies, information, and coordination. Only limited research has been conducted in this field to date. Nevertheless, in both developed and developing states, studies that focused on regulations and laws activated in health systems during emergencies, identified inconsistency and incoherence. The Ebola outbreak plaguing West Africa since 2014 has global implications, challenges and paralleling results, that were identified in this review. Conclusions The review has shown the need to broaden international regulations, to deepen reciprocity between countries, and to consider LMICs health capacities, in order to strengthen the national health security. Adopting elements of the health legal preparedness model is recommended. PMID:26449204

  16. Acute Acquired Concomitant Esotropia

    PubMed Central

    Chen, Jingchang; Deng, Daming; Sun, Yuan; Shen, Tao; Cao, Guobin; Yan, Jianhua; Chen, Qiwen; Ye, Xuelian

    2015-01-01

    Abstract Acute acquired concomitant esotropia (AACE) is a rare, distinct subtype of esotropia. The purpose of this retrospective study was to describe the clinical characteristics and discuss the classification and etiology of AACE. Charts from 47 patients with AACE referred to our institute between October 2010 and November 2014 were reviewed. All participants underwent a complete medical history, ophthalmologic and orthoptic examinations, and brain and orbital imaging. Mean age at onset was 26.6 ± 12.2 years. Of the 18 cases with deviations ≤ 20 PD, 16 presented with diplopia at distance and fusion at near vision at the onset of deviation; differences between distance and near deviations were < 8 PD; all cases except one were treated with prism and diplopia resolved. Of the 29 cases with deviations > 20 PD, 5 were mild hypermetropic with age at onset between 5 and 19 years, 16 were myopic, and 8 were emmetropic with age at onset > 12 years; 24 were surgically treated and 5 cases remained under observation; all 24 cases achieved normal retinal correspondence or fusion or stereopsis on postoperative day 1 in synoptophore; in 23 cases diplopia or visual confusion resolved postoperatively. Of the 47 cases, brain and orbital imaging in 2 cases revealed a tumor in the cerebellopontine angle and 1 case involved spinocerebellar ataxia as revealed by genetic testing. AACE in this study was characterized by a sudden onset of concomitant nonaccommodative esotropia with diplopia or visual confusion at 5 years of age or older and the potential for normal binocular vision. We suggest that AACE can be divided into 2 subgroups consisting of patients with relatively small versus large angle deviations. Coexisting or underlying neurological diseases were infrequent in AACE. PMID:26705210

  17. Birth Preparedness and Complication Readiness among Pregnant Women in Duguna Fango District, Wolayta Zone, Ethiopia

    PubMed Central

    2015-01-01

    Background Birth Preparedness and Complication Readiness is a strategy to promote the timely use of skilled maternal and neonatal care, especially during childbirth, based on the theory that preparing for childbirth and being ready for complications reduces delays in obtaining this care. Objective This study was conducted to assess birth preparedness and complication readiness and its associated factors among pregnant woman in Duguna Fango District in Wolayta Zone, South Ethiopia. Methods A community based cross-sectional study was conducted in 2013, on a sample of 578 pregnant women. Data were collected using pre-tested and structured questionnaire. The collected data were analyzed by SPSS for windows version 16.0. The women were asked whether they followed the desired five steps while pregnant: identified a trained birth attendant, identified a health facility, arranged for transport, identified blood donor and saved money for emergency. Taking at least three steps was considered being well-prepared. Results Among 578 pregnant women only one tenth (10.7%) of pregnant women identified skilled provider. Only 103 (18.1%) arranged transportation to health facility. Two hundred forty eight (43.6%) identified health facility for delivery and/or for obstetric emergencies. more than half (54.1%) of families saved money for incurred costs of delivery and emergency if needed. only few 17(3%) identified potential blood donor in case of emergency. Two hundred sixty four (46.4%) of the respondents reported that they intended to deliver at home, and more than half (53.6) planned to deliver at health facilities. Overall less than one fifth 18.3% of pregnant women were well prepared. The adjusted multivariate model showed that significant predictors for being well-prepared were maternal availing of antenatal services (AOR = 2.95, 95% CI: 1.62–5.37), being pregnant for the first time (AOR = 3.37, 95% CI: 1.45–7.82), having knowledge of at least two danger signs during

  18. Acquiring a Second Language for School.

    ERIC Educational Resources Information Center

    Collier, Virginia P.

    1995-01-01

    This report offers a conceptual model for use with language minority children who are entering a new school when they must acquire the language of the majority student population. The model has four development components or processes: sociocultural, linguistic, academic, and cognitive. These four components are described in detail. Research is…

  19. 3 CFR 8854 - Proclamation 8854 of August 31, 2012. National Preparedness Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... our preparedness for disasters of all types—from cyber incidents and acts of terrorism to tornadoes... preparedness and observe this month by working together to enhance our national security, resilience,...

  20. 75 FR 18214 - Board of Scientific Counselors, Coordinating Office for Terrorism Preparedness and Emergency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... Office for Terrorism Preparedness and Emergency Response (BSC, COTPER) \\1\\ \\1\\ The Coordinating Office for Terrorism Preparedness and Emergency Response has been renamed and is now the Office of...

  1. 76 FR 58466 - Request for Comments on World Health Organization Pandemic Influenza Preparedness Framework

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... influenza preparedness via the Federal Register on September 14, 2010; 75 FR 55776-55777. The Department of... International Trade Administration Request for Comments on World Health Organization Pandemic Influenza... the World Health Organization Pandemic Influenza Preparedness Framework (...

  2. 44 CFR 352.22 - Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... NUCLEAR POWER PLANTS: EMERGENCY PREPAREDNESS PLANNING Federal Participation § 352.22 Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC). Under 44 CFR part 351, the role of...

  3. 44 CFR 352.22 - Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... NUCLEAR POWER PLANTS: EMERGENCY PREPAREDNESS PLANNING Federal Participation § 352.22 Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC). Under 44 CFR part 351, the role of...

  4. 16 CFR 801.2 - Acquiring and acquired persons.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... confer control of X and therefore will file as an acquiring person. Because A held the plant prior to the... within two persons, “A” and “B.” Under this section, if V is to acquire corporation X, both “A” and “B... person. Examples: 1. Assume that person “Q” will acquire voting securities of corporation X held by...

  5. 16 CFR 801.2 - Acquiring and acquired persons.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... confer control of X and therefore will file as an acquiring person. Because A held the plant prior to the... within two persons, “A” and “B.” Under this section, if V is to acquire corporation X, both “A” and “B... person. Examples: 1. Assume that person “Q” will acquire voting securities of corporation X held by...

  6. The pitfalls of bioterrorism preparedness: the anthrax and smallpox experiences.

    PubMed

    Cohen, Hillel W; Gould, Robert M; Sidel, Victor W

    2004-10-01

    Bioterrorism preparedness programs have contributed to death, illness, and waste of public health resources without evidence of benefit. Several deaths and many serious illnesses have resulted from the smallpox vaccination program; yet there is no clear evidence that a threat of smallpox exposure ever existed. The anthrax spores released in 2001 have been linked to secret US military laboratories-the resultant illnesses and deaths might not have occurred if those laboratories were not in operation. The present expansion of bioterrorism preparedness programs will continue to squander health resources, increase the dangers of accidental or purposeful release of dangerous pathogens, and further undermine efforts to enforce international treaties to ban biological and chemical weapons. The public health community should acknowledge the substantial harm that bioterrorism preparedness has already caused and develop mechanisms to increase our public health resources and to allocate them to address the world's real health needs. PMID:15451727

  7. 44 CFR 352.22 - Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Federal Radiological Preparedness Coordinating Committee (FRPCC). Under 44 CFR part 351, the role of the... Radiological Preparedness Coordinating Committee (FRPCC). 352.22 Section 352.22 Emergency Management and... and local governments in their radiological emergency planning and preparedness activities. Under...

  8. 44 CFR 352.22 - Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Federal Radiological Preparedness Coordinating Committee (FRPCC). Under 44 CFR part 351, the role of the... Radiological Preparedness Coordinating Committee (FRPCC). 352.22 Section 352.22 Emergency Management and... and local governments in their radiological emergency planning and preparedness activities. Under...

  9. 44 CFR 352.22 - Functions of the Federal Radiological Preparedness Coordinating Committee (FRPCC).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Federal Radiological Preparedness Coordinating Committee (FRPCC). Under 44 CFR part 351, the role of the... Radiological Preparedness Coordinating Committee (FRPCC). 352.22 Section 352.22 Emergency Management and... and local governments in their radiological emergency planning and preparedness activities. Under...

  10. 33 CFR 203.21 - Disaster preparedness responsibilities of non-Federal interests.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Disaster preparedness..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE EMERGENCY EMPLOYMENT OF ARMY AND OTHER RESOURCES, NATURAL DISASTER PROCEDURES Disaster Preparedness § 203.21 Disaster preparedness responsibilities of...

  11. 76 FR 77235 - Board of Scientific Counselors, Office of Public Health Preparedness and Response: Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Public Health Preparedness and Response: Notice of Charter Renewal This gives notice under the Federal... of Public Health Preparedness and Response, Centers for Disease Control and Prevention (CDC... Scientific Counselors, Office of Public Health Preparedness and Response, CDC, HHS, 1600 Clifton Road...

  12. 78 FR 69682 - Board of Scientific Counselors, Office of Public Health Preparedness and Response: Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... Public Health Preparedness and Response: Notice of Charter Renewal This gives notice under the Federal... of Public Health Preparedness and Response, Centers for Disease Control and Prevention (CDC... Scientific Counselors, Office of Public Health Preparedness and Response, CDC, HHS, 1600 Clifton Road,...

  13. 78 FR 15369 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal..., Office of Public Health Preparedness and Response (OPHPR), concerning strategies and goals for the... following topics: Public Health Preparedness and Response Policy Updates; improving critical...

  14. Critical Event Preparedness and Response: Keynote Address to the 2006 Sloan Research Workshop by Jon Links

    ERIC Educational Resources Information Center

    Moore, Janet C.

    2008-01-01

    At the intersection of online education and preparedness, Johns Hopkins University's (JHU) Center for Public Health Preparedness provides all-hazards preparedness and response training for public health and public safety professionals. This report comes from Jonathan Links' keynote address to the Sloan Summer Research Workshop in Baltimore,…

  15. 3 CFR 8679 - Proclamation 8679 of May 20, 2011. National Hurricane Preparedness Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Hurricane Preparedness Week, 2011 8679 Proclamation 8679 Presidential Documents Proclamations Proclamation 8679 of May 20, 2011 Proc. 8679 National Hurricane Preparedness Week, 2011By the President of the United States of America A Proclamation National Hurricane Preparedness Week highlights the importance...

  16. Incident Management Preparedness and Coordination Toolkit

    2013-04-01

    As with many professions, safety planners and first responders tend to be specialists in certain areas. To be truly useful, tools should be tailored to meet their specific needs. Thus, general software suites aimed at the professional geographic information system (GIS) community might not be the best solution for a first responder with little training in GIS terminology and techniques. On the other hand, commonly used web-based map viewers may not have the capability tomore » be customized for the planning, response, and recovery (PR&R) mission. Data formats should be open and foster easy information flow among local, state, and federal partners. Tools should be free or low-cost to address real-world budget constraints at the local level. They also need to work both with and without a network connection to be robust. The Incident Management Preparedness and Coordination Toolkit (IMPACT) can satisfy many of these needs while working in harmony with established systems at the local, state, and federal levels. The IMPACT software framework, termed the Geospatial Integrated Problem Solving Environment (GIPSE), organizes tasks, tools, and resources for the end user. It uses the concept of software wizards to both customize and extend its functionality. On the Tasks panel are a number of buttons used to initiate various operations. Similar to macros, these task buttons launch scripts that utilize the full functionality of the underlying foundational components such as the SQL spatial database and ORNL-developed map editor. The user is presented with a series of instruction pages which are implemented with HTML for interactivity. On each page are links which initiate specific actions such as creating a map showing various features. Additional tasks may be quickly programmed and added to the panel. The end user can customize the graphical interface to faciltate its use during an emergency. One of the major components of IMPACT is the ORNL Geospatial Viewer (OGV). It is

  17. Incident Management Preparedness and Coordination Toolkit

    SciTech Connect

    Koch, Daniel B.

    2013-04-01

    As with many professions, safety planners and first responders tend to be specialists in certain areas. To be truly useful, tools should be tailored to meet their specific needs. Thus, general software suites aimed at the professional geographic information system (GIS) community might not be the best solution for a first responder with little training in GIS terminology and techniques. On the other hand, commonly used web-based map viewers may not have the capability to be customized for the planning, response, and recovery (PR&R) mission. Data formats should be open and foster easy information flow among local, state, and federal partners. Tools should be free or low-cost to address real-world budget constraints at the local level. They also need to work both with and without a network connection to be robust. The Incident Management Preparedness and Coordination Toolkit (IMPACT) can satisfy many of these needs while working in harmony with established systems at the local, state, and federal levels. The IMPACT software framework, termed the Geospatial Integrated Problem Solving Environment (GIPSE), organizes tasks, tools, and resources for the end user. It uses the concept of software wizards to both customize and extend its functionality. On the Tasks panel are a number of buttons used to initiate various operations. Similar to macros, these task buttons launch scripts that utilize the full functionality of the underlying foundational components such as the SQL spatial database and ORNL-developed map editor. The user is presented with a series of instruction pages which are implemented with HTML for interactivity. On each page are links which initiate specific actions such as creating a map showing various features. Additional tasks may be quickly programmed and added to the panel. The end user can customize the graphical interface to faciltate its use during an emergency. One of the major components of IMPACT is the ORNL Geospatial Viewer (OGV). It is used to

  18. 16 CFR 801.2 - Acquiring and acquired persons.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... acquired person is the pre-acquisition ultimate parent entity of the entity. (ii) The value of an... directors of B. A is deemed to be acquiring all of the assets of B as a result. (g) Transfers of patent... transfer of patent rights covered by this paragraph constitutes an asset acquisition; and (3) Patent...

  19. Associative Learning Through Acquired Salience

    PubMed Central

    Treviño, Mario

    2016-01-01

    Most associative learning studies describe the salience of stimuli as a fixed learning-rate parameter. Presumptive saliency signals, however, have also been linked to motivational and attentional processes. An interesting possibility, therefore, is that discriminative stimuli could also acquire salience as they become powerful predictors of outcomes. To explore this idea, we first characterized and extracted the learning curves from mice trained with discriminative images offering varying degrees of structural similarity. Next, we fitted a linear model of associative learning coupled to a series of mathematical representations for stimulus salience. We found that the best prediction, from the set of tested models, was one in which the visual salience depended on stimulus similarity and a non-linear function of the associative strength. Therefore, these analytic results support the idea that the net salience of a stimulus depends both on the items' effective salience and the motivational state of the subject that learns about it. Moreover, this dual salience model can explain why learning about a stimulus not only depends on the effective salience during acquisition but also on the specific learning trajectory that was used to reach this state. Our mathematical description could be instrumental for understanding aberrant salience acquisition under stressful situations and in neuropsychiatric disorders like schizophrenia, obsessive-compulsive disorder, and addiction. PMID:26793078

  20. Associative Learning Through Acquired Salience.

    PubMed

    Treviño, Mario

    2015-01-01

    Most associative learning studies describe the salience of stimuli as a fixed learning-rate parameter. Presumptive saliency signals, however, have also been linked to motivational and attentional processes. An interesting possibility, therefore, is that discriminative stimuli could also acquire salience as they become powerful predictors of outcomes. To explore this idea, we first characterized and extracted the learning curves from mice trained with discriminative images offering varying degrees of structural similarity. Next, we fitted a linear model of associative learning coupled to a series of mathematical representations for stimulus salience. We found that the best prediction, from the set of tested models, was one in which the visual salience depended on stimulus similarity and a non-linear function of the associative strength. Therefore, these analytic results support the idea that the net salience of a stimulus depends both on the items' effective salience and the motivational state of the subject that learns about it. Moreover, this dual salience model can explain why learning about a stimulus not only depends on the effective salience during acquisition but also on the specific learning trajectory that was used to reach this state. Our mathematical description could be instrumental for understanding aberrant salience acquisition under stressful situations and in neuropsychiatric disorders like schizophrenia, obsessive-compulsive disorder, and addiction. PMID:26793078

  1. A new method of exercising pandemic preparedness through an interactive simulation and visualization.

    PubMed

    Araz, Ozgur M; Jehn, Megan; Lant, Timothy; Fowler, John W

    2012-06-01

    As seen in the spring 2009 A/H1N1 influenza outbreak, influenza pandemics can have profound social, legal and economic effects. This experience has also made the importance of public health preparedness exercises more evident. Universities face unique challenges with respect to pandemic preparedness due to their dense student populations, location within the larger community and frequent student/faculty international travel. Depending on the social structure of the community, different mitigation strategies should be applied for decreasing the severity and transmissibility of the disease. To this end, Arizona State University has developed a simulation model and tabletop exercise that facilitates decision-maker interactions around emergency-response scenarios. This simulation gives policy makers the ability to see the real-time impact of their decisions. Therefore, tabletop exercises with computer simulations are developed to practice these decisions, which can possibly give opportunities for practicing better policy implementations. This paper introduces a new method of designing and performing table-top exercises for pandemic influenza via state-of-the-art technologies including system visualization and group decision making with a supporting simulation model. The presented exercise methodology can increase readiness for a pandemic through the support of computer and information technologies and the survey results that we include in this paper certainly support this result. The video scenarios and the computer simulation model make the exercise appear very compelling and real, which makes this presented method of exercising different than the other table-top exercises in the literature. Finally, designing a pandemic preparedness exercise with supporting technologies can help identifying the communication gaps between responsible authorities and advance the table-top exercising methodology. PMID:20960052

  2. Generic tsunami scenarios for disasters and early warning preparedness

    NASA Astrophysics Data System (ADS)

    Guillande, Richard; Gardi, Annalisa; Valencia, Nathalia; Salaün, Tugdual

    2010-05-01

    The implementation of the tsunami early warning systems in the NE Atlantic and Mediterranean regions will occur in countries with no preparedness and very little knowledge of potentially affected coastal zones by the various tsunami sources. The final link to coastal communities will be sirens to distribute in the concerned areas. The SCHEMA project aims at elaboration of a generic method to consider various parameters of a particular tsunami scenario. A scenario corresponds to a specific source with a given magnitude or intensity. Since we do not consider only the remote sources with possibilities of warning, local earthquake and submarine landslides are also translated in scenarios to allow the civil protections, municipalities and local stakeholders to assess cases with no real warning possibility, where life will be saved by self evacuation in nearby shelter areas or buildings. The specific temporal dimension of tsunami phenomenon is considered. Oceanic propagation time, expected duration of dangerous waves and wavelength are taken into account with their level of uncertainties. Scenarios are presented by maps and layouts with various information: inundation extension, submersion depth, receding sea limit, currents velocity or modulus of flow, modeled damage level to buildings, affected networks and lifelines. Variable dimensions such as residing or working population, by hour of the day and by season are also considered. Secondary vulnerability factors which may increase damage level to buildings are added (potentially floating objects which may turn into projectiles). The potential evacuation routes and obstacles are represented to support installation of warning networks and definition of shelters as well as evacuation routes. The scenarios are calculated using accurate digital bathymetric and topographic model with less than 10 m ground resolution allowing a very detailed mapping. This accuracy is especially important for scenarios with moderate waves for

  3. Children Acquire Emotion Categories Gradually

    ERIC Educational Resources Information Center

    Widen, Sherri C.; Russell, James A.

    2008-01-01

    Some accounts imply that basic-level emotion categories are acquired early and quickly, whereas others imply that they are acquired later and more gradually. Our study examined this question for fear, happiness, sadness, and anger in the context of children's categorization of emotional facial expressions. Children (N=168, 2-5 years) first labeled…

  4. Transportation radiological emergency preparedness: STAR 95 Exercise final report

    SciTech Connect

    1998-05-12

    Emergency response for a transportation accident involving radiological materials, while not inherently difficult, presents a challenge for several reasons. These accidents, although they can occur anywhere, are rare. Also, although the health consequences are usually slight, accidents involving radioactive materials generally cause a great deal of concern, both for the emergency responders and the general public. How can communities be prepared for an event that requires some technical knowledge, but is so rare that it will never occur in most areas, without expending an effort disproportionate to the actual risk? How can one appropriately deal with an event that may cause excessive public concern? These questions are at the heart of the preparedness issues this program addressed. The overall goal of the Transportation Emergency Preparedness Program was to establish the framework for a coordinated response by all levels of government to a transportation accident involving radioactive material. The Program involved both preparedness activities and the development, conduct and evaluation of a field exercise in Saratoga County, New York. This Report concentrates on the functional activities, lessons learned, recommendations, and action plans for improving preparedness and response to a transportation accident involving radioactive materials.

  5. Green paper on bio-preparedness--general comments.

    PubMed

    Sirbu, Manuela

    2010-01-01

    The Commission's Green Paper on Bio-preparedness represents an important signal that the European Commission is actively involved in, working on issues related to bio-preparedness across all Member States and the international Community. In 2006, the Commission held two seminars on European Bio Preparedness and a workshop on Transport and Traceability of Bio materials. The results and recommendations emerging from these discussions have been inserted in this Green Paper. The document intends to stimulate a debate within and between the Member States and to launch a process of consultation on how to reduce biological risks and to enhance preparedness and response. All the national authorities responsible for risk prevention and response, human, animal and plant health, customs, civil protection, law enforcement authorities, the military, bio-industry, epidemiological and health communities, academic institutions and bioresearch institutes are therefore called to be involved, to contribute and to improve the ability of the EU to prevent, respond to and recover from a biological incident or deliberate criminal activity. PMID:21254743

  6. Earthquake Preparedness 101: Planning Guidelines for Colleges and Universities.

    ERIC Educational Resources Information Center

    California Governor's Office, Sacramento.

    This publication is a guide for California colleges and universities wishing to prepare for earthquakes. An introduction aimed at institutional leaders emphasizes that earthquake preparedness is required by law and argues that there is much that can be done to prepare for earthquakes. The second section, addressed to the disaster planner, offers…

  7. Disaster Preparedness Resource Guide for Child Welfare Agencies

    ERIC Educational Resources Information Center

    Berne, Rebecca

    2009-01-01

    This guide offers best practices for disaster management at child welfare agencies. Its recommendations are firmly rooted in published disaster-related research and the advice of human service and preparedness experts. It is not a reinvention of disaster management--much quality work has been done in this field--but a synthesis of experts'…

  8. Multicultural Education Knowledgebase, Attitudes and Preparedness for Diversity

    ERIC Educational Resources Information Center

    Wasonga, Teresa A.

    2005-01-01

    Purpose: The paper aims to investigate the effect of multicultural knowledgebase on attitudes and feelings of preparedness to teach children from diverse backgrounds among pre-service teachers. Currently issues of multicultural education have been heightened by the academic achievement gap and emphasis on standardized test-scores as the indicator…

  9. Disaster Preparedness for University/Community Transit Systems

    ERIC Educational Resources Information Center

    Robinson, Geary Lynn

    2011-01-01

    Public transportation, with its open access, creates an opportunity for masses of people to be hurt while using transit services during human-made or natural disasters. This dissertation reviews the body of academic and professional literature and recent disaster events to characterize the current state of preparedness for disasters affecting…

  10. Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

    SciTech Connect

    Blanchard, A.

    2000-02-28

    This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program.

  11. Characterization of emergency preparedness at DOE contractor facilities

    SciTech Connect

    Gillings, J.C.; Murphy, B.L.; Corbit, C.D.; MacLellan, J.A.; Essig, T.H.; Higby, D.P.; Hooker, C.D.; Laughlin, G.J.; Stoetzel, G.A.; Swinth, K.L.

    1984-07-01

    A study of emergency preparedness capabilities at DOE facilities was initiated following the incident at the Three Mile Island (TMI) Nuclear Power Station. It was designed to parallel but expand on a study on emergency preparedness instrumentation that was conducted in 1970 by Pacific Northwest Laboratory. The 1970 survey findings led to the publication of four reports on performance criteria for radiological emergency instrumentation. Three of these reports - BNWL-1635 (Selby et al. 1972), BNWL-1742 (Anderson et al. 1974) and BNWL-1857 (Andersen et al. 1976) - addressed the criteria for emergency instrumentation at reactors, mixed oxide fuel fabrication plants, and fuel reprocessing plants, respectively. The fourth report, BNWL-1991 (Bramson et al. 1976), addressed evaluation testing and calibration methodology for these instruments. This report is presented in three parts. Part One is a review of the BNWL documents to determine whether they are applicable to state-of-the-art instrument capabilities. The Appendix to Part One provides a comparison between the instrument performance criteria established in BNWL-1991 to applicable American National Standards Institute (ANSI) standards for portable survey and contamination meters, installed radiation and area monitors, effluent monitors, calibration techniques, criticality detection systems, alarm systems, and direct reading dosimeters. Part Two compares the 1970 survey results with the 1980 survey results to identify trends in emergency preparedness. Part Three is a discussion of the results of the 1980 emergency preparedness survey and the supporting data for each of the 15 modules. 8 references. (ACR)

  12. Assessing Student Teaching Experiences: Teacher Candidates' Perceptions of Preparedness

    ERIC Educational Resources Information Center

    Lee, Joohi; Tice, Kathleen; Collins, Denise; Brown, Amber; Smith, Cleta; Fox, Jill

    2012-01-01

    The purpose of this study is to investigate the effectiveness of student teaching experiences by measuring teacher candidates' perceptions of their preparedness. The participants were 130 teacher candidates who had completed their student teaching as part of a program preparing them to teach children in pre-K through grade 4. Teacher candidates…

  13. College Students' Perceptions of College Preparedness

    ERIC Educational Resources Information Center

    Matteson, Star

    2013-01-01

    As educational leaders struggle to meet state and federal mandates, many students graduate from high school without the skills necessary to meet the demands of a college education. Guided by the tenets of constructivism, this qualitative case study explored college students' perceptions of their college preparedness through math, science, and…

  14. Perceived Academic Preparedness of First-Generation Latino College Students

    ERIC Educational Resources Information Center

    Boden, Karen

    2011-01-01

    First-generation Latino college students may be characterized as underprepared for college. Research points to low performance on placement tests. However, students may not perceive themselves as academically underprepared for college. This study explored first-generation Latino students' perceptions of their academic preparedness. Seven students…

  15. Does Gender Matter? University Library Access and Career Preparedness

    ERIC Educational Resources Information Center

    Smith, Daniella

    2015-01-01

    The purpose of this exploratory study was to examine how the gender of distance learning students related to variables such as the perception of the availability of library resources, technology available at home and work, technology provided by a university for distance learning, and career preparedness. A total of 166 master's students in the…

  16. Preparedness to Implement Wellness Strategies: Perceptions of School Counselors

    ERIC Educational Resources Information Center

    Burnett, Tena

    2012-01-01

    The purpose of this study is to survey school counselors to determine their knowledge and perceived preparedness to implement wellness strategies in school counseling programs. Wellness plans are a requirement for thousands of public school districts in the United States. There are no established standards for the training of school counselors in…

  17. Teachers, Schools and Using Evidence: Considerations of Preparedness

    ERIC Educational Resources Information Center

    Parr, Judy M.; Timperley, Helen S.

    2008-01-01

    Despite assessment being viewed as integral to practice, there are questions about schools' preparedness to engage in this process. Data from three studies conducted in New Zealand primary schools explore whether use of student achievement data is part of the professional canon or skill set. (1) When implementing new literacy materials, evidence…

  18. Disaster Preparedness Manual and Workbook for Pennsylvania Libraries and Archives.

    ERIC Educational Resources Information Center

    Swan, Elizabeth, Ed.; And Others

    This document suggests components for a sound disaster plan for libraries and archives. The planning process includes four steps which are covered in this manual: educating the staff about disaster preparedness literature; planning to prevent disasters; preparing to respond to an emergency and minimize its effects; and planning how to restore…

  19. 77 FR 25504 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... COMMISSION Draft Emergency Preparedness Frequently Asked Questions AGENCY: Nuclear Regulatory Commission... asked questions (EPFAQs). These EPFAQs will be used to provide clarification of guidance documents... Frequently Asked Questions is available electronically under ADAMS Accession Number ML12108A151, and it...

  20. Alternative Certification Programs & Pre-Service Teacher Preparedness

    ERIC Educational Resources Information Center

    Koehler, Adrie; Feldhaus, Charles Robert; Fernandez, Eugenia; Hundley, Stephen

    2013-01-01

    This explanatory sequential mixed methods research study investigated motives and purpose exhibited by professionals transitioning from careers in science, technology, engineering and math (STEM) to secondary education. The study also analyzed personal perceptions of teaching preparedness, and explored barriers to successful teaching. STEM career…

  1. The importance of establishing a national health security preparedness index.

    PubMed

    Lumpkin, John R; Miller, Yoon K; Inglesby, Tom; Links, Jonathan M; Schwartz, Angela T; Slemp, Catherine C; Burhans, Robert L; Blumenstock, James; Khan, Ali S

    2013-03-01

    Natural disasters, infectious disease epidemics, terrorism, and major events like the nuclear incident at Fukushima all pose major potential challenges to public health and security. Events such as the anthrax letters of 2001, Hurricanes Katrina, Irene, and Sandy, severe acute respiratory syndrome (SARS) and West Nile virus outbreaks, and the 2009 H1N1 influenza pandemic have demonstrated that public health, emergency management, and national security efforts are interconnected. These and other events have increased the national resolve and the resources committed to improving the national health security infrastructure. However, as fiscal pressures force federal, state, and local governments to examine spending, there is a growing need to demonstrate both what the investment in public health preparedness has bought and where gaps remain in our nation's health security. To address these needs, the Association of State and Territorial Health Officials (ASTHO), through a cooperative agreement with the Centers for Disease Control and Prevention (CDC) Office of Public Health Preparedness and Response (PHPR), is creating an annual measure of health security and preparedness at the national and state levels: the National Health Security Preparedness Index (NHSPI). PMID:23506403

  2. A Disaster Preparedness Plan for Small Public Libraries, 2002.

    ERIC Educational Resources Information Center

    Haines, Jan, Comp.

    The State Library of Ohio designed this disaster preparedness plan to assist small libraries in gathering information that will be invaluable in the event of an emergency. This plan, which focuses on fire and water disaster prevention, is devoted to using simple and inexpensive measures to prevent a disaster or to lessen its effect. The plan…

  3. 42 CFR 485.727 - Condition of participation: Disaster preparedness.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Condition of participation: Disaster preparedness. 485.727 Section 485.727 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION CONDITIONS OF PARTICIPATION: SPECIALIZED PROVIDERS Conditions of Participation for...

  4. Academic Preparedness of First-Generation College Students: Different Perspectives

    ERIC Educational Resources Information Center

    Atherton, Matthew C.

    2014-01-01

    As student populations continue to become more diversified, institutions must understand students' academic preparedness to better serve them. A significant amount of research and literature focuses on experiences of students whose parents had little or no college education. Although these first-generation students have much in common with…

  5. Primary Teacher Trainees Preparedness to Teach Science: A Gender Perspective

    ERIC Educational Resources Information Center

    Mutisya, Sammy M.

    2015-01-01

    The purpose of this study was to determine Primary Teacher Education (PTE) Trainees' perceptions regarding their preparedness to teach science in primary schools. A descriptive survey research design was used and stratified proportionate random sampling techniques used to select 177 males and 172 females. The study found out that more male trainee…

  6. A Study of Terrorism Emergency Preparedness Policies in School Districts

    ERIC Educational Resources Information Center

    Umoh, Emmanuel

    2013-01-01

    The threat of terrorism is a concern in public facilities including schools. This study focused on school districts in a southwestern state. Terrorism emergency preparedness policies are well-documented as measures to protect students and staff in school districts from terrorism threats and vulnerabilities. However, those threats and…

  7. The Culturally Responsive Teacher Preparedness Scale: An Exploratory Study

    ERIC Educational Resources Information Center

    Hsiao, Yun-Ju

    2015-01-01

    The purpose of this study was to investigate the competencies of culturally responsive teaching and construct a Culturally Responsive Teacher Preparedness Scale (CRTPS) for the use of teacher preparation programs and preservice teachers. Competencies listed in the scale were identified through literature reviews and input from experts. The…

  8. 76 FR 30491 - National Hurricane Preparedness Week, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... thirty-fifth. (Presidential Sig.) [FR Doc. 2011-13166 Filed 5-24-11; 11:15 am] Billing code 3195-W1-P ... May 25, 2011 Part III The President Proclamation 8679--National Hurricane Preparedness Week, 2011 Proclamation 8680--National Safe Boating Week, 2011 Proclamation 8681--Armed Forces Day, 2011 Proclamation...

  9. School Security and Crisis Preparedness: Make It Your Business.

    ERIC Educational Resources Information Center

    Trump, Kenneth S.

    1999-01-01

    The top five security risks in today's schools include aggressive behavior, weapons possession or use, drug trafficking, gangs, and "stranger danger." Home-made bomb threats are common. This article also discusses security system costs, risk-reduction frameworks, security assessments, crisis-preparedness guidelines, and security-related staffing.…

  10. Public School Nurses' Preparedness for a Hearing Aid Monitoring Program.

    ERIC Educational Resources Information Center

    Johnson, Carole E.; And Others

    1992-01-01

    This investigation surveyed public school nurses' (n=30) preparedness to participate in a hearing aid monitoring program. Results indicated some deficiencies in nurses' exposure to, knowledge of, and basic skill level with hearing aids, hearing aid batteries, and ear molds. (Author/DB)

  11. How Did Light Acquire a Velocity?

    ERIC Educational Resources Information Center

    Lauginie, Pierre

    2013-01-01

    We discuss how light acquired a velocity through history, from the ancient Greeks to the early modern era. Combining abstract debates, models of light, practical needs, planned research and chance, this history illustrates several key points that should be brought out in science education.

  12. Disaster Response and Preparedness Application: Emergency Environmental Response Tool (EERT)

    NASA Technical Reports Server (NTRS)

    Smoot, James; Carr, Hugh; Jester, Keith

    2003-01-01

    In 2000, the National Aeronautics and Space Administration (NASA) Environmental Office at the John C. Stennis Space Center (SSC) developed an Environmental Geographic Information Systems (EGIS) database. NASA had previously developed a GIS database at SSC to assist in the NASA Environmental Office's management of the Center. This GIS became the basis for the NASA-wide EGIS project, which was proposed after the applicability of the SSC database was demonstrated. Since its completion, the SSC EGIS has aided the Environmental Office with noise pollution modeling, land cover assessment, wetlands delineation, environmental hazards mapping, and critical habitat delineation for protected species. At SSC, facility management and safety officers are responsible for ensuring the physical security of the facilities, staff, and equipment as well as for responding to environmental emergencies, such as accidental releases of hazardous materials. All phases of emergency management (planning, mitigation, preparedness, and response) depend on data reliability and system interoperability from a variety of sources to determine the size and scope of the emergency operation. Because geospatial data are now available for all NASA facilities, it was suggested that this data could be incorporated into a computerized management information program to assist facility managers. The idea was that the information system could improve both the effectiveness and the efficiency of managing and controlling actions associated with disaster, homeland security, and other activities. It was decided to use SSC as a pilot site to demonstrate the efficacy of having a baseline, computerized management information system that ultimately was referred to as the Emergency Environmental Response Tool (EERT).

  13. Knowledge, awareness, and preparedness unlinked in layperson

    NASA Astrophysics Data System (ADS)

    Oki, S.; Nakayachi, K.

    2012-12-01

    take action for disaster prevention. Examinees are 200 high school and undergraduate students who do not major in Earth science. We first gave them information of basic knowledge such as tectonic backgrounds of Japan and the latest research outcomes such as long-term evaluation of large earthquake occurrence or the strong ground motion, and then asked what they felt. The results show that neither the basic knowledge nor the latest research outcomes motivate examinees to take action for the disaster prevention or even to give awareness. We then showed them the movies of the past earthquake disasters and some episodes who had lost their loved ones from the recent earthquakes, and asked the same question. As psychology implies, this information made examinees feel dread and they became aware of the risks lie ahead. But still, they did not mention what to do to prevent the tragedy. In the presentation, we would like to show the difficulty to make people take action to protect their lives from earthquake disasters. We also show peoples' preparedness/unpreparedness with the information released by a Japanese research group in the late January saying the possibility of metropolitan Tokyo earthquake being 70% in this coming 4-year.

  14. Assessment of Hospital Pharmacy Preparedness for Mass Casualty Events

    PubMed Central

    Awad, Nadia I.; Cocchio, Craig

    2015-01-01

    Objectives: To assess the preparedness of hospital pharmacies in New Jersey to provide pharmaceutical services in mass casualty scenarios. Methods: An electronic cross-sectional survey was developed to assess the general knowledge of available resources and attitudes toward the preparedness of the pharmacy department. Results: Out of 60 invitations to participate, 18 surveys (30%) were completed. Respondents practiced at community hospitals (12, 66.6%) with no trauma center designation (11, 67.4%) that served more than 500 licensed beds (five, 29.4%). Six respondents (35.3%) indicated that 75,000 to 100,000 patients visited their emergency departments annually. Seventeen sites (94.4%) reported the existence of an institutional disaster preparedness protocol; 10 (55.5%) indicated that there is a specific plan for the pharmacy department. Most respondents (10, 55.5%) were unsure whether their hospitals had an adequate supply of analgesics, rapid sequence intubation agents, vasopressors, antiemetics, respiratory medications, ophthalmics, oral antimicrobials, and chemical-weapon-specific antidotes. Five (27.7%) agreed that the pharmacy disaster plan included processes to ensure care for patients already hospitalized, and four (22.2%) agreed that the quantity of medication was adequate to treat patients and hospital employees if necessary. Medication stock and quantities were determined based on national or international guidelines at three (16.6%) institutions surveyed. Conclusion: This survey demonstrates a lack of general consensus regarding hospital pharmacy preparedness for mass casualty scenarios despite individualized institutional protocols for disaster preparedness. Standardized recommendations from government and/or professional pharmacy organizations should be developed to guide the preparation of hospital pharmacy departments for mass casualty scenarios. PMID:25859121

  15. Peer-Mentored Preparedness (PM-Prep): A New Disaster Preparedness Program for Adults Living Independently in the Community

    ERIC Educational Resources Information Center

    Eisenman, David Paul; Bazzano, Alicia; Koniak-Griffin, Deborah; Tseng, Chi-hong; Lewis, Mary-Ann; Lamb, Kerry; Lehrer, Danise

    2014-01-01

    The authors studied a health promotion program called PM-Prep (Peer-Mentored Prep), which was designed to improve disaster preparedness among adults living independently in the community. PM-Prep consists of four 2-hour classes co-taught by a health educator and peer-mentors. Adults were randomly assigned to an experimental arm or a wait-list…

  16. Towards an Integrated Flood Preparedness and Response: Centralized Data Access, Analysis, and Visualization

    NASA Astrophysics Data System (ADS)

    Demir, I.; Krajewski, W. F.

    2014-12-01

    Recent advances in internet and cyberinfrastucture technologies have provided the capability to understand the hydrological and meteorological systems at space and time scales that are critical for making accurate understanding and prediction of flooding, and emergency preparedness. A novel example of a cyberinfrastructure platform for flood preparedness and response is the Iowa Flood Center's Iowa Flood Information System (IFIS). IFIS is a one-stop web-platform to access community-based flood conditions, forecasts, visualizations, inundation maps and flood-related data, information, and applications. An enormous volume of real-time observational data from a variety of sensors and remote sensing resources (radars, rain gauges, stream sensors, etc.) and complex flood inundation models are staged on a user-friendly maps environment that is accessible to the general public. IFIS has developed into a very successful tool used by agencies, decision-makers, and the general public throughout Iowa to better understand their local watershed and their personal and community flood risk, and to monitor local stream and river levels. IFIS helps communities make better-informed decisions on the occurrence of floods, and alerts communities in advance to help minimize flood damages. IFIS is widely used by general public in Iowa and the Midwest region with over 120,000 unique users, and became main source of information for many newspapers and TV stations in Iowa. IFIS has features for general public to improve emergency preparedness, and for decision makers to support emergency response and recovery efforts. IFIS is also a great platform for educators and local authorities to educate students and public on flooding with games, easy to use interactive environment, and data rich system.

  17. Canine rabies in Australia: a review of preparedness and research needs.

    PubMed

    Sparkes, J; Fleming, P J S; Ballard, G; Scott-Orr, H; Durr, S; Ward, M P

    2015-06-01

    Australia is unique as a populated continent in that canine rabies is exotic, with only one likely incursion in 1867. This is despite the presence of a widespread free-ranging dog population, which includes the naturalized dingo, feral domestic dogs and dingo-dog cross-breeds. To Australia's immediate north, rabies has recently spread within the Indonesian archipelago, with outbreaks occurring in historically free islands to the east including Bali, Flores, Ambon and the Tanimbar Islands. Australia depends on strict quarantine protocols to prevent importation of a rabid animal, but the risk of illegal animal movements by fishing and recreational vessels circumventing quarantine remains. Predicting where rabies will enter Australia is important, but understanding dog population dynamics and interactions, including contact rates in and around human populations, is essential for rabies preparedness. The interactions among and between Australia's large populations of wild, free-roaming and restrained domestic dogs require quantification for rabies incursions to be detected and controlled. The imminent risk of rabies breaching Australian borders makes the development of disease spread models that will assist in the deployment of cost-effective surveillance, improve preventive strategies and guide disease management protocols vitally important. Here, we critically review Australia's preparedness for rabies, discuss prevailing assumptions and models, identify knowledge deficits in free-roaming dog ecology relating to rabies maintenance and speculate on the likely consequences of endemic rabies for Australia. PMID:24934203

  18. Preparedness Perceptions, Sociodemographic Characteristics, and Level of Household Preparedness for Public Health Emergencies: Behavioral Risk Factor Surveillance System, 2006-2010.

    PubMed

    DeBastiani, Summer D; Strine, Tara W; Vagi, Sara J; Barnett, Daniel J; Kahn, Emily B

    2015-01-01

    Our objective was to inform state and community interventions focused on increasing household preparedness by examining the association between self-reported possession of household disaster preparedness items (ie, a 3-day supply of food and water, a written evacuation plan, and a working radio and flashlight) and perceptions of household preparedness on a 3-point scale from "well prepared" to "not at all prepared." Data were analyzed from 14 states participating in a large state-based telephone survey: the 2006-2010 Behavioral Risk Factor Surveillance System (BRFSS) (n = 104,654). Only 25.3% of the population felt they were well prepared, and only 12.3% had all 5 of the recommended items. Fewer than half the households surveyed had 4 or more of the recommended preparedness items (34.1%). Respondents were more likely to report their households were well prepared as the number of preparedness items possessed by their household increased. Risk factors for having no preparedness items were: younger age, being female, lower levels of education, and requesting the survey to be conducted in Spanish. To increase household disaster preparedness, more community-based preparedness education campaigns targeting vulnerable populations, such as those with limited English abilities and lower reading levels, are needed. PMID:26348094

  19. Re-inventing prevention? - An evaluation of tools for strengthening private preparedness for floods and heavy rains

    NASA Astrophysics Data System (ADS)

    Rohland, Stefanie; Pfurtscheller, Clemens; Seebauer, Sebastian

    2016-04-01

    Keywords: private preparedness, property protection, flood, heavy rains, Transtheoretical Model, evaluation of methods and tools Experiences in Europe and Austria from coping with numerous floods and heavy rain events in recent decades point to room for improvement in reducing damages and adverse effects. One of the emerging issues is private preparedness, which has only received punctual attention in Austria until now. Current activities to promote property protection are, however, not underpinned by a long-term strategy, thus minimizing their cumulative effect. While printed brochures and online information are widely available, innovative information services, tailored to and actively addressing specific target groups, are thin on the ground. This project reviews (national as well as international) established approaches, with a focus on German-speaking areas, checking their long-term effectiveness with the help of expert workshops and an empirical analysis of survey data. The Transtheoretical Model (Prochaska, 1977) serves as the analytical framework: We assign specific tools to distinct stages of behavioural change. People's openness to absorb risk information or their willingness to engage in private preparedness depend on an incremental process of considering, appraising, introducing and finally maintaining preventive actions. Based on this stage-specific perspective and the workshop results, gaps of intervention are identified to define best-practice examples and recommendations that can be realized within the prevailing legislative and organizational framework at national, regional and local level in Austria.

  20. Seismological investigation of the National Data Centre Preparedness Exercise 2013

    NASA Astrophysics Data System (ADS)

    Gestermann, Nicolai; Hartmann, Gernot; Ross, J. Ole; Ceranna, Lars

    2015-04-01

    The Comprehensive Nuclear-Test-Ban Treaty (CTBT) prohibits all kinds of nuclear explosions conducted on Earth - underground, underwater or in the atmosphere. The verification regime of the CTBT is designed to detect any treaty violation. While the data of the International Monitoring System (IMS) is collected, processed and technically analyzed at the International Data Centre (IDC) of the CTBT-Organization, National Data Centres (NDC) of the member states provide interpretation and advice to their government concerning suspicious detections. The NDC Preparedness Exercises (NPE) are regularly performed dealing with fictitious treaty violations to practice the combined analysis of CTBT verification technologies. These exercises should help to evaluate the effectiveness of analysis procedures applied at NDCs and the quality, completeness and usefulness of IDC products for example. The exercise trigger of NPE2013 is a combination of a tempo-spatial indication pointing to a certain waveform event and simulated radionuclide concentrations generated by forward Atmospheric Transport Modelling based on a fictitious release. For the waveform event the date (4 Sept. 2013) is given and the region is communicated in a map showing the fictitious state of "Frisia" at the Coast of the North Sea in Central Europe. The potential connection between the waveform and radionuclide evidence remains unclear for exercise participants. The verification task was to identify the waveform event and to investigate potential sources of the radionuclide findings. The final question was whether the findings are CTBT relevant and justify a request for On-Site-Inspection in "Frisia". The seismic event was not included in the Reviewed Event Bulletin (REB) of the IDC. The available detections from the closest seismic IMS stations lead to a epicenter accuracy of about 24 km which is not sufficient to specify the 1000 km2 inspection area in case of an OSI. With use of data from local stations and

  1. Assessment of Emergency Preparedness Modules in Introductory Pharmacy Practice Experiences

    PubMed Central

    von Waldner, Trina; McEwen, Deanna W.; White, Catherine A.

    2016-01-01

    Objective. To determine the impact of emergency preparedness simulations in mass triage and mass dispensing on student pharmacist performance and perceived competency when assuming pharmacist roles in disaster situations. Design. Second-year student pharmacists (144) completed two 3-hour simulations focusing on mass triage and mass dispensing. The mass triage simulation consisted of virtual and live victims to be triaged and assigned a transport order. In the mass dispensing simulation, students assumed patient and pharmacist roles in a point-of-dispensing exercise for influenza. Assessment. For the mass triage simulation, students were challenged most by determining which patients could wait for emergency care but did well assessing those who required immediate or minimal care (83% and 64% correct, respectively). During the mass dispensing simulation, students performed screening and dispensing functions with accuracy rates of 88% and 90%, respectively. Conclusion. Student pharmacists performed well in screening and dispensing functions, but struggled with mass casualty triage during emergency preparedness simulations. PMID:27073276

  2. Assessment of Emergency Preparedness Modules in Introductory Pharmacy Practice Experiences.

    PubMed

    Hannings, Ashley N; von Waldner, Trina; McEwen, Deanna W; White, Catherine A

    2016-03-25

    Objective. To determine the impact of emergency preparedness simulations in mass triage and mass dispensing on student pharmacist performance and perceived competency when assuming pharmacist roles in disaster situations. Design. Second-year student pharmacists (144) completed two 3-hour simulations focusing on mass triage and mass dispensing. The mass triage simulation consisted of virtual and live victims to be triaged and assigned a transport order. In the mass dispensing simulation, students assumed patient and pharmacist roles in a point-of-dispensing exercise for influenza. Assessment. For the mass triage simulation, students were challenged most by determining which patients could wait for emergency care but did well assessing those who required immediate or minimal care (83% and 64% correct, respectively). During the mass dispensing simulation, students performed screening and dispensing functions with accuracy rates of 88% and 90%, respectively. Conclusion. Student pharmacists performed well in screening and dispensing functions, but struggled with mass casualty triage during emergency preparedness simulations. PMID:27073276

  3. Exploring nursing students' level of preparedness for disaster response.

    PubMed

    Schmidt, Cheryl K; Davis, Jennifer M; Sanders, Jenna L; Chapman, Laura A; Cisco, Mary Catherine; Hady, Arlene R

    2011-01-01

    This descriptive study explores students' perceptions of personal and program preparedness for disasters. Participants in this online survey included 1,348 nursing students from every state plus Guam, Puerto Rico, and theVirgin Islands. The study explored three questions: a) the level of preparedness, including learning about different types of disasters, preparing disaster plans, creating disaster kits, and participating in community disaster response efforts; b) the impact of disasters on nursing students; and c) strategies to assist nursing students during disasters. Results indicated that nursing students throughout the country are generally not well prepared for disasters. Nurse educators need to develop strategies to prepare their students for disasters. The American Red Cross provides templates for organizations, including colleges and universities, to prepare their campuses for emergencies. Faculty need to collaborate with staff and students to develop and implement plans appropriate for their programs. PMID:22235694

  4. An academic approach to climate change emergency preparedness.

    PubMed

    Trask, Jeffrey A

    To achieve effective emergency management and business continuity, all hazards should be considered during the planning and preparedness process. In recent years, several new hazards have attracted the attention of Emergency Management and Business Continuity practitioners. Climate change presents a unique challenge. Practitioners must rely on historical data combined with scientific projections to guide their planning and preparedness efforts. This article examines how an academic institution's emergency management programme can plan successfully for this hazard by focusing on best practices in the area of building cross-departmental and cross-jurisdictional relationships. Examples of scientific data related to the hazard of climate change will be presented along with the latest guidance from the Federal Emergency Management Agency encouraging the planning for future hazards. The article presents a functional exercise in which this hazard was prominently featured, and presents testimony from subject matter experts. Recommendations for emergency management and business continuity programmes are so provided. PMID:26642169

  5. The WOMED model of benign thyroid disease: Acquired magnesium deficiency due to physical and psychological stressors relates to dysfunction of oxidative phosphorylation

    PubMed Central

    Moncayo, Roy; Moncayo, Helga

    2014-01-01

    Background The aim of this study was to discern whether a relation between biochemical parameters, sonography and musculoskeletal data exists in cases of hyperthyroidism and whether they are modifiable through supplementation with selenomethionine and magnesium citrate as well as by acupuncture and manual medicine methods. Results A direct correlation between whole blood selenium and serum magnesium was found in subjects without thyroid disease and in menopausal women while it was reversed in cases of thyroid diseases as well as in patients with depression, infection, and in infertile women. Vascularization indices were elevated in cases of newly diagnosed benign thyroid diseases. Musculoskeletal changes i.e. lateral tension and idiopathic moving toes, as well as situations of physical and psychological stress and minor trauma and infection led to an increase of vascularization. Magnesium levels correlated negatively with these two conditions. The supplementation brought a reduction of the vascularization indices and reduced the incidence of idiopathic moving toes. Treatment of lateral tension required manual medicine methods and acupuncture (gastrocnemius). A small subgroup of patients showed a further reduction of hyper-vascularization after receiving coenzyme Q10. Conclusions We interpret the elevated thyroid vascularization and low magnesium levels as signs of an inflammatory process related to the musculoskeletal changes. Improvement of thyroid function and morphology can be achieved after correcting the influence of stressors together with the supplementation regime. We hypothesize that the central biochemical event in thyroid disease is that of an acquired, altered mitochondrial function due to deficiency of magnesium, selenium, and coenzyme Q10. PMID:26675817

  6. Guidelines to improve airport preparedness against chemical and biological terrorism.

    SciTech Connect

    Edwards, Donna M.; Price, Phillip N.; Gordon, Susanna P.; Gadgil, Ashok

    2005-05-01

    Guidelines to Improve Airport Preparedness Against Chemical and Biological Terrorism is a 100-page document that makes concrete recommendations on improving security and assessing vulnerable areas and helps its readers understand the nature of chemical and biological attacks. The report has been turned over to Airports Council International (ACI) and the American Association of Airport Executives (AAAE), two organizations that together represent the interests of thousands of airport personnel and facilities in the U.S. and around the world.

  7. A baseline assessment of emergency planning and preparedness in Italian universities.

    PubMed

    Marincioni, Fausto; Fraboni, Rita

    2012-04-01

    Besides offering teaching and research services, schools and universities also must provide for the safety and security of their employees, students, and visitors. This paper describes emergency preparedness in a sample of Italian universities. In particular it examines risk perception within a specific professional category (university safety and security officers) in a specific cultural context (Italy). In addition, it discusses the transposition and implementation in a European Union (EU) member state of EU Council Directive 89/391/EEC of 12 June 1989, on the introduction of measures to encourage improvements in the safety and health of workers. The findings highlight heterogeneous and fragmented emergency management models within the Italian university system, underlining the need for a stricter framework of standardised safety protocols and emergency management guidelines. The study also points out that enhancing emergency planning and preparedness in Italian universities entails increasing safety leadership, employee engagement and individual responsibility for safety and security; essentially, it necessitates improving the culture of risk prevention. PMID:21995686

  8. State of the art in risk analysis of workforce criticality influencing disaster preparedness for interdependent systems.

    PubMed

    Santos, Joost R; Herrera, Lucia Castro; Yu, Krista Danielle S; Pagsuyoin, Sheree Ann T; Tan, Raymond R

    2014-06-01

    The objective of this article is to discuss a needed paradigm shift in disaster risk analysis to emphasize the role of the workforce in managing the recovery of interdependent infrastructure and economic systems. Much of the work that has been done on disaster risk analysis has focused primarily on preparedness and recovery strategies for disrupted infrastructure systems. The reliability of systems such as transportation, electric power, and telecommunications is crucial in sustaining business processes, supply chains, and regional livelihoods, as well as ensuring the availability of vital services in the aftermath of disasters. There has been a growing momentum in recognizing workforce criticality in the aftermath of disasters; nevertheless, significant gaps still remain in modeling, assessing, and managing workforce disruptions and their associated ripple effects to other interdependent systems. The workforce plays a pivotal role in ensuring that a disrupted region continues to function and subsequently recover from the adverse effects of disasters. With this in mind, this article presents a review of recent studies that have underscored the criticality of workforce sectors in formulating synergistic preparedness and recovery policies for interdependent infrastructure and regional economic systems. PMID:24593287

  9. PRIORITIZATION OF PEDIATRIC CBRNE DISASTER PREPAREDNESS EDUCATION AND TRAINING NEEDS

    PubMed Central

    Siegel, David; Strauss-Riggs, Kandra; Needle, Scott

    2014-01-01

    Children are the members of our population who are most vulnerable to the effects of a chemical, biological, radiological, nuclear or explosive (CBRNE) attack. It has been over 12 years since 9/11 and the majority of clinicians who would be providing care to children in the event of another attack still lack the requisite disaster preparedness training. The purpose of this report is to provide an overview of the recent developments that will enable the affordable creation of key CBRNE educational and just in time material. In 2011, the National Center for Disaster Medicine and Public Health (NCDMPH) convened a pediatric disaster preparedness conference. Much of the initial groundwork for development of a pediatric disaster preparedness curriculum, including the identification of target audiences and requisite role specific CBRNE curriculum content, was the product of this conference. Much of the needed pediatric education and training content for the diagnosis and treatment of the injurious effects of CBRNE has recently been both developed and well vetted. Bringing together these efforts in an educational program will result in a workforce that is better trained and prepared to address the needs of children impacted by these types of disasters. PMID:25587241

  10. Perceptions of older people on disaster response and preparedness.

    PubMed

    Duggan, Seana; Deeny, Pat; Spelman, Ruth; Vitale, Catherine T

    2010-03-01

    Most disasters occur in developing countries but in the last decade due to the increasing threat of floods, air disasters and terrorist threat, disaster response and preparedness is a growing global concern. Due to an ageing population across the world, older people now constitute a significant proportion of those at risk from disasters. This paper reports on a qualitative study carried out in Sri Lanka and in the United States where a group of older people were asked about aspects of disaster response and preparedness. The group from Sri Lanka (n=9) who had direct experience of the 2004 Indian Ocean Tsunami were asked how they perceived international aid relief and a group of white Caucasians from East Coast USA (n=8) were asked about disaster preparedness. Findings indicate that both groups had similar issues albeit that they were looking at different phases of the disaster cycle and from different cultural perspectives. Both groups identified issues related to, protecting the rights of the older person and preventing loss of independence in responding and preparing for a disaster, mistrust of government and access to resources and all expressed strong feelings of self-responsibility. PMID:20925760

  11. Demographic Determinants of Disaster Preparedness Behaviors Amongst Tehran Inhabitants, Iran

    PubMed Central

    Najafi, Mehdi; Ardalan, Ali; Akbarisari, Ali; Noorbala, Ahmad Ali; Jabbari, Hossain

    2015-01-01

    Background: Tehran is vulnerable to natural hazards, especially earthquakes. Disaster preparedness behaviors (DPB) are measures that can mitigate the adverse consequences of disasters. Demographic factors affect DPB, however, the role of some of these factors is not still clear. By understanding these effects, disaster specialists could design interventions toward specific demographics. In the present study, we aimed to investigate demographic determinants of DPB. Methods: This cross-sectional survey was conducted in August 2014. The target population included inhabitants of Tehran who were 18 years or older. A total of 1250 participants were selected randomly and interviewed using a standardized questionnaire. Results: Results of our study showed that monthly income level, previous disaster experience, residential district and occupation are demographic factors that influence DPB significantly. However, disaster preparedness was not affected by gender, educational level, number of household members, home type, home ownership and being the head of household. Conclusion: To promote DPB in Tehran, disaster specialists should focus on improving DPB in low-income and unemployed people, and individuals who live in high risk districts, especially in those who have not experienced disasters. Key words: Disaster, Preparedness behavior, Demographic determinants.     PMID:26767148

  12. Raising Awareness and Preparedness to Earthquake and Tsunami Risk

    NASA Astrophysics Data System (ADS)

    Custódio, Susana; Mata, Isabel; Silveira, Graça; Matias, Luis

    2014-05-01

    In the field of natural risks, awareness and preparedness are deeply rooted on education and outreach (EO). In this presentation we will review of a series of EO activities carried out in Portugal over the last years with the goals of increasing the awareness and preparedness of the population to earthquake and tsunami risk. Portugal is a country with a long history of destructive earthquakes, which includes the largest historical earthquake of Europe: the 1755 great Lisbon earthquake, a landmark in the history of seismology. However, recurrence times between large earthquakes are long, resulting on widespread unconsciousness of earthquake and tsunami risk, most noticeable on younger people who never experienced strong earthquakes. Over the past years we developed a series of EO activities with the aims of increasing the scientific understanding of solid Earth dynamics and promoting risk adequate behaviors. These activities have been extremely well received by the public, encouraging us to pursue efforts in this field. Different activities were devised for students in 1) kindergarten and primary school; 2) highschool; 3) pre-university; 4) university. Specific activities were developed for teachers. Other activities aimed at reaching the general public. We found that the balance between preparedness and scientific contents of the activities had to very adaptable to the specific public. In this presentation we will summarize the activities developed for each type of public, their rationale, the public's reaction, and we will share the lessons learned from our rewarding experience.

  13. A framework for assessing e-health preparedness.

    PubMed

    Wickramasinghe, Nilmini S; Fadlalla, Adam M A; Geisler, Elie; Schaffer, Jonathan L

    2005-01-01

    Whilst healthcare is the biggest service industry on the globe, it has yet to realise the full potential of the e-business revolution in the form of e-health. This is due to many reasons including the fact that the healthcare industry is faced with many complex challenges in trying to deliver cost-effective, high-value, accessible healthcare and has traditionally been slow to embrace new business techniques and technologies. Given that e-health, to a great extent, is a macro level concern that has far reaching micro level implications, this paper firstly develops a framework to assess a country's preparedness with respect to embracing e-health (the application of e-commerce to healthcare) and from this an e-health preparedness grid to facilitate the assessment of any e-health initiative. Taken together, the integrative framework and preparedness grid provide useful and necessary tools to enable successful e-health initiatives to ensue by helping country and/or an organisation within a country to identify and thus address areas that require further attention in order for it to undertake a successful e-health initiative. PMID:18048213

  14. National Alliance for Radiation Readiness: Leveraging Partnerships to Increase Preparedness.

    PubMed

    Blumenstock, James S; Allen, Meredith

    2016-02-01

    The National Alliance for Radiation Readiness (NARR) is an alliance of 16 national member organizations that have banded together to serve as the collective "voice of health" in radiological preparedness through: • participation in national dialogues on radiological emergency issues; • provision of thoughtful feedback on documents, policies, and guidelines; and • convening of partners to raise awareness of and resolve radiological emergency issues. NARR benefits from the intersection and interaction of public health, radiation control, healthcare, and emergency management professionals--all with an interest in bolstering the nation's preparedness for a radiological or nuclear incident. NARR is able to provide a unique perspective on radiological and nuclear preparedness by creating multi-disciplinary workgroups to develop guidance, recommendations, and provide subject matter feedback. NARR aims to build response and recovery capacity and capabilities by supporting the sharing of resources and tools, including technical methods and information through the development of an online clearinghouse. NARR also aims to identify and disseminate best practices, as well as define and educate on the roles and responsibilities of local, state, and federal government and the numerous agencies involved with the response to a radiological emergency. PMID:26717184

  15. US Civilian Smallpox Preparedness and Response Program, 2003.

    PubMed

    Strikas, Raymond A; Neff, Linda J; Rotz, Lisa; Cono, Joanne; Knutson, Donna; Henderson, Joseph; Orenstein, Walter A

    2008-03-15

    Variola virus, the cause of smallpox disease, has been deemed a possible bioterrorism agent. Since November 2001, federal, state, and local public health partners implemented activities to prepare for a possible smallpox outbreak. The Centers for Disease Control and Prevention (CDC) produced and delivered training and educational materials for smallpox preparedness in many formats, developed detailed smallpox vaccine information statements about vaccine contraindications and vaccination site care, and established mechanisms to monitor and respond to adverse events after smallpox vaccination. The last included enhancements to the Vaccine Adverse Event Reporting System, a pregnancy registry for inadvertently vaccinated pregnant women, and a Clinician Telephone Information Line to collect reports about adverse events. The civilian responder vaccination program was conducted with rigorous safety procedures, and few historically recognized adverse events were observed. However, myocarditis and/or pericarditis was newly recognized as an adverse event caused by the New York City Board of Health vaccinia vaccine strain. This smallpox preparedness program put into place a number of measures to advance the United States' readiness for a smallpox outbreak that have assisted in preparedness for other threats. PMID:18284355

  16. Evidence of the effectiveness of health sector preparedness in disaster response: the example of four earthquakes.

    PubMed

    Bissell, Richard A; Pinet, Luis; Nelson, Matthew; Levy, Matthew

    2004-01-01

    In this article, evidence that health sector preparedness improves response performance in disasters was examined. Case fatality and survival data were compared for four earthquakes, in relation to health sector emergency preparedness levels. Vast differences in performance were found. The two California systems, with a high preparedness index, had low case fatality rates (about one death per 100 injuries). Kobe, Japan, with mixed levels of preparedness, had 31 deaths per 100 injuries, and Armenia (low preparedness index) had 167. Public health and health sector preparedness made a significant difference in the ability to respond effectively to meet patient needs in disasters, although it is only one of several factors that determine the health outcome of disaster victims. PMID:15596966

  17. Theory-based approaches to understanding public emergency preparedness: implications for effective health and risk communication.

    PubMed

    Paek, Hye-Jin; Hilyard, Karen; Freimuth, Vicki; Barge, J Kevin; Mindlin, Michele

    2010-06-01

    Recent natural and human-caused disasters have awakened public health officials to the importance of emergency preparedness. Guided by health behavior and media effects theories, the analysis of a statewide survey in Georgia reveals that self-efficacy, subjective norm, and emergency news exposure are positively associated with the respondents' possession of emergency items and their stages of emergency preparedness. Practical implications suggest less focus on demographics as the sole predictor of emergency preparedness and more comprehensive measures of preparedness, including both a person's cognitive stage of preparedness and checklists of emergency items on hand. We highlight the utility of theory-based approaches for understanding and predicting public emergency preparedness as a way to enable more effective health and risk communication. PMID:20574880

  18. Disaster preparedness: what training do our interns receive during medical school?

    PubMed

    Jasper, Edward; Berg, Katherine; Reid, Matthew; Gomella, Patrick; Weber, Danielle; Schaeffer, Arielle; Crawford, Albert; Mealey, Kathleen; Berg, Dale

    2013-01-01

    Disaster preparedness training is a critical component of medical student education. Despite recent natural and man-made disasters, there is no national consensus on a disaster preparedness curriculum. The authors designed a survey to assess prior disaster preparedness training among incoming interns at an academic teaching hospital. In 2010, the authors surveyed incoming interns (n = 130) regarding the number of hours of training in disaster preparedness received during medical school, including formal didactic sessions and simulation, and their level of self-perceived proficiency in disaster management. Survey respondents represented 42 medical schools located in 20 states. Results demonstrated that 47% of interns received formal training in disaster preparedness in medical school; 64% of these training programs included some type of simulation. There is a need to improve the level of disaster preparedness training in medical school. A national curriculum should be developed with aspects that promote knowledge retention. PMID:23341470

  19. Transportation Emergency Preparedness Program Plan, U.S. Department of Energy Region 6

    SciTech Connect

    Marsha Keister

    2010-04-01

    The United States Department of Energy (DOE) Region 6 Transportation Emergency Preparedness Program Plan (TEPP Plan) operates within the framework of the DOE emergency management system for developing, coordinating, and directing emergency planning, preparedness, and readiness assurance activities for radiological transportation incidents. The DOE Region 6 TEPP Plan is a narrative description of the DOE Transportation Emergency Preparedness Program activities, training and technical assistance provided to states and tribes along DOE's transportation corridors in DOE Region 6.

  20. Opperational Systems for Emergency Preparedness and Response

    SciTech Connect

    Sugiyama, G; Nasstrom, J S; Baskett, R

    2003-11-10

    Operational systems predict the consequences of atmospheric releases of hazardous materials for real-time emergency response, pre-event planning, and post-incident assessment. Such systems provide federal, state, and local agencies, emergency planners and responders, public health officials, military personnel, and other users with critical information on which to base life-and-death decisions on safe zones for siting of incident command posts, sheltering-in-place or evacuation advisories, the need for protective equipment, and the utilization of hospital and health care resources. A range of operational modeling capabilities is required to support different types of release events, distance scales, and response times. Fast-response deployable models are used to perform hazard assessments and initial response functions, and can serve as a backup when connections to a reach-back center are not available. Higher-fidelity three-dimensional dispersion models, coupled to real-time observational data and numerical weather prediction model output, are used for real-time response and support expert quality-assured predictions and refined assessments. Computational fluid dynamics models, which explicitly resolve urban structures, are used for high fidelity applications including vulnerability analyses and planning studies. This paper will briefly discuss the types and capabilities of models used or under development for emergency response systems, customer products, supporting data, and a few representative examples of operational systems. Some selected research priorities are summarized in the final sections.

  1. Building performance-based accountability with limited empirical evidence: performance measurement for public health preparedness.

    PubMed

    Shelton, Shoshana R; Nelson, Christopher D; McLees, Anita W; Mumford, Karen; Thomas, Craig

    2013-08-01

    Efforts to respond to performance-based accountability mandates for public health emergency preparedness have been hindered by a weak evidence base linking preparedness activities with response outcomes. We describe an approach to measure development that was successfully implemented in the Centers for Disease Control and Prevention Public Health Emergency Preparedness Cooperative Agreement. The approach leverages insights from process mapping and experts to guide measure selection, and provides mechanisms for reducing performance-irrelevant variation in measurement data. Also, issues are identified that need to be addressed to advance the science of measurement in public health emergency preparedness. PMID:24229520

  2. Acquired Equivalence Changes Stimulus Representations

    ERIC Educational Resources Information Center

    Meeter, M.; Shohamy, D.; Myers, C. E.

    2009-01-01

    Acquired equivalence is a paradigm in which generalization is increased between two superficially dissimilar stimuli (or antecedents) that have previously been associated with similar outcomes (or consequents). Several possible mechanisms have been proposed, including changes in stimulus representations, either in the form of added associations or…

  3. Proposing a New Conceptual Model and an Exemplar Measure Using Health Information: Technology to Examine the Impact of Relational Nurse Continuity on Hospital-Acquired Pressure Ulcers.

    PubMed

    Stifter, Janet; Yao, Yingwei; Lopez, Karen Dunn; Khokhar, Ashfaq; Wilkie, Diana J; Keenan, Gail M

    2015-01-01

    The influence of the staffing variable relational nurse continuity on patient outcomes has been rarely studied and with inconclusive results. Multiple definitions and an absence of systematic methods for measuring the influence of continuity have resulted in its exclusion from nurse-staffing studies and conceptual models. We present a new conceptual model and an innovative use of health information technology to measure relational nurse continuity and to demonstrate the potential for bringing the results of big data science back to the bedside. Understanding the power of big data to address critical clinical issues may foster a new direction for nursing administration theory development. PMID:26244480

  4. An Assessment of State Board of Pharmacy Legal Documents for Public Health Emergency Preparedness.

    PubMed

    Ford, Heath; Trent, Shane; Wickizer, Stephen

    2016-03-25

    Objective. To estimate pharmaceutical emergency preparedness of US states and commonwealth territories. Methods. A quantitative content analysis was performed to evaluate board of pharmacy legal documents (ie, statutes, rules, and regulations) for the presence of the 2006 Rules for Public Health Emergencies (RPHE) from the National Association of Boards of Pharmacy's (NABP) Model Pharmacy Practice Act. Results. The median number of state-adopted RPHE was one, which was significantly less than the hypothesized value of four. Rule Two, which recommended policies and procedures for reporting disasters, was adopted significantly more than other RPHE. Ten states incorporated language specific to public health emergency refill dispensing, and among these, only six allowed 30-day refill quantities. Conclusion. Based on the 2006 NABP model rules, it does not appear that states are prepared to expedite an effective pharmaceutical response during a public health emergency. Boards of pharmacy should consider adding the eight RPHE to their state pharmacy practice acts. PMID:27073273

  5. An Assessment of State Board of Pharmacy Legal Documents for Public Health Emergency Preparedness

    PubMed Central

    Trent, Shane; Wickizer, Stephen

    2016-01-01

    Objective. To estimate pharmaceutical emergency preparedness of US states and commonwealth territories. Methods. A quantitative content analysis was performed to evaluate board of pharmacy legal documents (ie, statutes, rules, and regulations) for the presence of the 2006 Rules for Public Health Emergencies (RPHE) from the National Association of Boards of Pharmacy’s (NABP) Model Pharmacy Practice Act. Results. The median number of state-adopted RPHE was one, which was significantly less than the hypothesized value of four. Rule Two, which recommended policies and procedures for reporting disasters, was adopted significantly more than other RPHE. Ten states incorporated language specific to public health emergency refill dispensing, and among these, only six allowed 30-day refill quantities. Conclusion. Based on the 2006 NABP model rules, it does not appear that states are prepared to expedite an effective pharmaceutical response during a public health emergency. Boards of pharmacy should consider adding the eight RPHE to their state pharmacy practice acts. PMID:27073273

  6. MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process.

    PubMed

    Yuan, Jinxian; Huang, Hao; Zhou, Xin; Liu, Xi; Ou, Shu; Xu, Tao; Li, Ruohan; Ma, Limin; Chen, Yangmei

    2016-01-01

    Increasing evidence suggests that epilepsy is the result of synaptic reorganization and pathological excitatory loop formation in the central nervous system; however, the mechanisms that regulate this process are not well understood. We proposed that microRNA-132 (miR-132) and p250GAP might play important roles in this process by activating the downstream Rho GTPase family. We tested this hypothesis using a magnesium-free medium-induced epileptic model of cultured hippocampal neurons. We investigated whether miR-132 regulates GTPase activity through p250GAP and found that Cdc42 was significantly activated in our experimental model. Silencing miR-132 inhibited the electrical excitability level of cultured epileptic neurons, whereas silencing p250GAP had an opposite effect. In addition, we verified the effect of miR-132 in vivo and found that silencing miR-132 inhibited the aberrant formation of dendritic spines and chronic spontaneous seizure in a lithium-pilocarpine-induced epileptic mouse model. Finally, we confirmed that silencing miR-132 has a neuroprotective effect on cultured epileptic neurons; however, this effect did not occur through the p250GAP pathway. Generally, silencing miR-132 may suppress spontaneous seizure activity through the miR-132/p250GAP/Cdc42 pathway by regulating the morphology and electrophysiology of dendritic spines; therefore, miR-132 may serve as a potential target for the development of antiepileptic drugs. PMID:27579184

  7. Type of visual feedback during practice influences the precision of the acquired internal model of a complex visuo-motor transformation.

    PubMed

    Sülzenbrück, Sandra; Heuer, Herbert

    2011-01-01

    This study investigated the influence of the type of visual feedback during practice with a complex visuo-motor transformation of a sliding two-sided lever on the acquisition of an internal model of the transformation. Three groups of participants, who practised with different types of visual feedback, were compared with regard to movement accuracy, curvature and movement time. One group had continuous visual feedback during practice and two groups were presented terminal visual feedback, either only the end position of the movement or the end position together with the trajectory of the cursor. Results showed that continuous visual feedback led to more precise movement end positions during practice than terminal visual feedback, but to less precise movements during open-loop tests. This finding indicates that terminal visual feedback supports the development of a precise internal model of a new visuo-motor transformation. However, even terminal feedback of the cursor trajectory during practice did not result in an internal model, which includes appropriate curvatures of hand movements. STATEMENT OF RELEVANCE: This paper presents results on the influence of type of visual feedback on learning the complex motor skill of controlling a sliding lever. These findings contribute to the conceptual basis of optimised training procedures for the acquisition of sensori-motor skills required for the mastery of instruments utilised in minimally invasive surgery. PMID:21181587

  8. MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process

    PubMed Central

    Huang, Hao; Zhou, Xin; Liu, Xi; Xu, Tao; Ma, Limin

    2016-01-01

    Increasing evidence suggests that epilepsy is the result of synaptic reorganization and pathological excitatory loop formation in the central nervous system; however, the mechanisms that regulate this process are not well understood. We proposed that microRNA-132 (miR-132) and p250GAP might play important roles in this process by activating the downstream Rho GTPase family. We tested this hypothesis using a magnesium-free medium-induced epileptic model of cultured hippocampal neurons. We investigated whether miR-132 regulates GTPase activity through p250GAP and found that Cdc42 was significantly activated in our experimental model. Silencing miR-132 inhibited the electrical excitability level of cultured epileptic neurons, whereas silencing p250GAP had an opposite effect. In addition, we verified the effect of miR-132 in vivo and found that silencing miR-132 inhibited the aberrant formation of dendritic spines and chronic spontaneous seizure in a lithium-pilocarpine-induced epileptic mouse model. Finally, we confirmed that silencing miR-132 has a neuroprotective effect on cultured epileptic neurons; however, this effect did not occur through the p250GAP pathway. Generally, silencing miR-132 may suppress spontaneous seizure activity through the miR-132/p250GAP/Cdc42 pathway by regulating the morphology and electrophysiology of dendritic spines; therefore, miR-132 may serve as a potential target for the development of antiepileptic drugs. PMID:27579184

  9. A No-Notice Drill of Hospital Preparedness in Responding to Ebola Virus Disease in Taiwan.

    PubMed

    Hsu, Shih-Min; Chien, Li-Jung; Tseng, Shu-Hui; Kuo, Steve H S

    2015-01-01

    The Ebola virus was first discovered in 1976, but the outbreak of Ebola virus disease that began in Guinea, West Africa, in December 2013 shocked the world. It is the largest and most severe epidemic of Ebola virus disease to date. The US Centers for Disease Control and Prevention confirmed that inadequate implementation of the policy of acquiring travel history led to a delay in identifying the first imported Ebola virus disease case. The Taiwan Centers for Disease Control developed a no-notice drill that used a simulated patient to assess hospitals' emergency preparedness capacity in responding to Ebola virus disease. Despite the fact that regular inspection shows that more than 90% of regional hospitals and medical centers inquired about patients' travel history, occupation, contact history, and cluster information, the no-notice drill revealed that more than 40% of regional hospitals and medical centers failed to ask emergency room patients about these factors. Therefore, to assist in inquiries about travel history, occupation, contact history, and cluster information in emergency triage and outpatient settings, the Taiwan CDC revised the criteria for hospital infection control inspection. It requested that hospitals issue appropriate reminders and implement process control mechanisms to block diagnostic processes in instances in which healthcare workers do not inquire about travel history, occupation, contact history, and cluster information. Furthermore, the Taiwan CDC will continue no-notice inspections in order to strengthen hospitals' infection control measures and reduce the risk of infectious disease transmission in the healthcare system. PMID:26381373

  10. A Conceptual Framework to Measure Systems’ Performance during Emergency Preparedness Exercises

    PubMed Central

    Savoia, Elena; Agboola, Foluso; Biddinger, Paul D.

    2014-01-01

    Large-scale public health emergencies require a sophisticated, coordinated response involving multiple entities to protect health and minimize suffering. However, the rarity of such emergencies presents a barrier to gathering observational data about the effectiveness of the public health response before such events occur. For this reason, public health practitioners increasingly have relied on simulated emergencies, known as “exercises” as proxies to test their emergency capabilities. However, the formal evaluation of performance in these exercises, historically has been inconsistent, and there is little research to describe how data acquired from simulated emergencies actually support conclusions about the quality of the public health emergency response system. Over the past six years, we have designed and evaluated more than seventy public health emergency exercises, collaborating with public health agencies, hospitals and others to test a wide variety of systems and their capabilities. Using the data and experience that we gathered, we have developed a conceptual framework that describes the essential elements necessary to consider when applying performance measurement science to public health emergency exercises. We suggest that this framework may assist practitioners and researchers who wish to better measure performance in exercises and to improve public health emergency preparedness. PMID:25233015

  11. Strategy for NMR metabolomic analysis of urine in mouse models of obesity--from sample collection to interpretation of acquired data.

    PubMed

    Pelantová, Helena; Bugáňová, Martina; Anýž, Jiří; Železná, Blanka; Maletínská, Lenka; Novák, Daniel; Haluzík, Martin; Kuzma, Marek

    2015-11-10

    The mouse model of monosodium glutamate induced obesity was used to examine and consequently optimize the strategy for analysis of urine samples by NMR spectroscopy. A set of nineteen easily detectable metabolites typical in obesity-related studies was selected. The impact of urine collection protocol, choice of (1)H NMR pulse sequence, and finally the impact of the normalization method on the detected concentration of selected metabolites were investigated. We demonstrated the crucial effect of food intake and diurnal rhythms resulting in the choice of a 24-hour fasting collection protocol as the most convenient for tracking obesity-induced increased sensitivity to fasting. It was shown that the Carr-Purcell-Meiboom-Gill (CPMG) experiment is a better alternative to one-dimensional nuclear Overhauser enhancement spectroscopy (1D-NOESY) for NMR analysis of mouse urine due to its ability to filter undesirable signals of proteins naturally present in rodent urine. Normalization to total spectral area provided comparable outcomes as did normalization to creatinine or probabilistic quotient normalization in the CPMG-based model. The optimized approach was found to be beneficial mainly for low abundant metabolites rarely monitored due to their overlap by strong protein signals. PMID:26263053

  12. Are short-term focused training courses on a phantom model using porcine gall bladder useful for trainees in acquiring basic laparoscopic skills?

    PubMed

    Bansal, Virinder Kumar; Panwar, Rajesh; Misra, Mahesh C; Bhattacharjee, Hemanga K; Jindal, Vikas; Loli, Athiko; Goswami, Amit; Krishna, Asuri; Tamang, Tseten

    2012-04-01

    The best training method in laparoscopic surgery has not been defined. We evaluated the efficacy of laparoscopic skills acquisition in a short-term focused program. Two hundred fifty-six participants undergoing training on a phantom model were divided into 2 groups. Group 1 had no exposure and group 2 had performed a few laparoscopic surgeries. Acquisition of laparoscopic skills was assessed by operation time and the modified Global Operative Assessment of Laparoscopic Skills (GOALS) scale. A questionnaire was sent to the participants after 3 to 6 months for assessment of impact of training. There was a statistically significant improvement in the assessed parameters and in the mean score of all 5 domains of GOALS. The participants in group 2 performed better than those in group 1 in the first case. The difference between both the groups disappeared after the training. Participants who responded to the questionnaire felt that training helped them in improving their performance in the operation theater. PMID:22487631

  13. Survival transcriptome in the coenzyme Q10 deficiency syndrome is acquired by epigenetic modifications: a modelling study for human coenzyme Q10 deficiencies

    PubMed Central

    Fernández-Ayala, Daniel J M; Guerra, Ignacio; Jiménez-Gancedo, Sandra; Cascajo, Maria V; Gavilán, Angela; DiMauro, Salvatore; Hirano, Michio; Briones, Paz; Artuch, Rafael; De Cabo, Rafael; Salviati, Leonardo; Navas, Plácido

    2013-01-01

    Objectives Coenzyme Q10 (CoQ10) deficiency syndrome is a rare condition that causes mitochondrial dysfunction and includes a variety of clinical presentations as encephalomyopathy, ataxia and renal failure. First, we sought to set up what all have in common, and then investigate why CoQ10 supplementation reverses the bioenergetics alterations in cultured cells but not all the cellular phenotypes. Design Modelling study This work models the transcriptome of human CoQ10 deficiency syndrome in primary fibroblast from patients and study the genetic response to CoQ10 treatment in these cells. Setting Four hospitals and medical centres from Spain, Italy and the USA, and two research laboratories from Spain and the USA. Participants Primary cells were collected from patients in the above centres. Measurements We characterised by microarray analysis the expression profile of fibroblasts from seven CoQ10-deficient patients (three had primary deficiency and four had a secondary form) and aged-matched controls, before and after CoQ10 supplementation. Results were validated by Q-RT-PCR. The profile of DNA (CpG) methylation was evaluated for a subset of gene with displayed altered expression. Results CoQ10-deficient fibroblasts (independently from the aetiology) showed a common transcriptomic profile that promotes cell survival by activating cell cycle and growth, cell stress responses and inhibiting cell death and immune responses. Energy production was supported mainly by glycolysis while CoQ10 supplementation restored oxidative phosphorylation. Expression of genes involved in cell death pathways was partially restored by treatment, while genes involved in differentiation, cell cycle and growth were not affected. Stably demethylated genes were unaffected by treatment whereas we observed restored gene expression in either non-methylated genes or those with an unchanged methylation pattern. Conclusions CoQ10 deficiency induces a specific transcriptomic profile that promotes

  14. Acquired causes of intestinal malabsorption.

    PubMed

    van der Heide, F

    2016-04-01

    This review focuses on the acquired causes, diagnosis, and treatment of intestinal malabsorption. Intestinal absorption is a complex process that depends on many variables, including the digestion of nutrients within the intestinal lumen, the absorptive surface of the small intestine, the membrane transport systems, and the epithelial absorptive enzymes. Acquired causes of malabsorption are classified by focussing on the three phases of digestion and absorption: 1) luminal/digestive phase, 2) mucosal/absorptive phase, and 3) transport phase. Most acquired diseases affect the luminal/digestive phase. These include short bowel syndrome, extensive small bowel inflammation, motility disorders, and deficiencies of digestive enzymes or bile salts. Diagnosis depends on symptoms, physical examination, and blood and stool tests. There is no gold standard for the diagnosis of malabsorption. Further testing should be based on the specific clinical context and the suspected underlying disease. Therapy is directed at nutritional support by enteral or parenteral feeding and screening for and supplementation of deficiencies in vitamins and minerals. Early enteral feeding is important for intestinal adaptation in short bowel syndrome. Medicinal treatment options for diarrhoea in malabsorption include loperamide, codeine, cholestyramine, or antibiotics. PMID:27086886

  15. Ebola virus disease surveillance and response preparedness in northern Ghana

    PubMed Central

    Adokiya, Martin N.; Awoonor-Williams, John K.

    2016-01-01

    Background The recent Ebola virus disease (EVD) outbreak has been described as unprecedented in terms of morbidity, mortality, and geographical extension. It also revealed many weaknesses and inadequacies for disease surveillance and response systems in Africa due to underqualified staff, cultural beliefs, and lack of trust for the formal health care sector. In 2014, Ghana had high risk of importation of EVD cases. Objective The objective of this study was to assess the EVD surveillance and response system in northern Ghana. Design This was an observational study conducted among 47 health workers (district directors, medical, disease control, and laboratory officers) in all 13 districts of the Upper East Region representing public, mission, and private health services. A semi-structured questionnaire with focus on core and support functions (e.g. detection, confirmation) was administered to the informants. Their responses were recorded according to specific themes. In addition, 34 weekly Integrated Disease Surveillance and Response reports (August 2014 to March 2015) were collated from each district. Results In 2014 and 2015, a total of 10 suspected Ebola cases were clinically diagnosed from four districts. Out of the suspected cases, eight died and the cause of death was unexplained. All the 10 suspected cases were reported, none was confirmed. The informants had knowledge on EVD surveillance and data reporting. However, there were gaps such as delayed reporting, low quality protective equipment (e.g. gloves, aprons), inadequate staff, and lack of laboratory capacity. The majority (38/47) of the respondents were not satisfied with EVD surveillance system and response preparedness due to lack of infrared thermometers, ineffective screening, and lack of isolation centres. Conclusion EVD surveillance and response preparedness is insufficient and the epidemic is a wake-up call for early detection and response preparedness. Ebola surveillance remains a neglected public

  16. Toxicological aspects of preparedness and aftercare for chemical-incidents.

    PubMed

    Schwenk, Michael; Kluge, Stefan; Jaroni, Hanswerner

    2005-10-30

    The threat of using chemical warfare agents still exists despite the 1993 Chemical Weapons Convention. Preparedness for attacks with chemical agents has become an important issue of national security programs. It can be anticipated that toxicologists will be increasingly involved in preparedness programs of their institutions and of the government, no matter whether they work in agencies, industry or universities. Toxicologists must get prepared to give fast and reliable advice in the case of an attack, a sabotage or an accident with release of toxic chemicals. They should be familiar with the principles of hazard management and with incident command structures and cooperate with first responders of other organizations involved such as fire department and medical emergency teams already in the planning phase. In the emergency planning phase, toxicologists are expected to help identifying possible hazards. Moreover, they consult public health services with regard to toxicosurveillance and advice hospitals regarding antidotes, decontamination procedures and shelters. They may be involved in the procurement of antidotes and of protective equipment and will support qualified analytical laboratories. In the response phase, toxicologists must be ready to gain and to interpret analytical data, to support the medical care of poisoned victims and to provide repeated risk assessment reports. This requires an on-scene access to databases and registries. The aftercare phase includes the identification of exposed persons, mapping of contaminated areas, organization of decontamination measures and the release of areas. A medical study may be initiated to observe long-term health effects. Good cooperation between regulatory and clinical toxicologists, specific education of toxicologist in the field of chemical emergencies and regular trainings are essential elements of good preparedness. PMID:16118031

  17. Partnered disaster preparedness: lessons learned from international events.

    PubMed

    Born, Christopher T; Cullison, Thomas R; Dean, Jeffrey A; Hayda, Roman A; McSwain, Norman; Riddles, Lawrence M; Shimkus, Albert J

    2011-01-01

    Military, governmental, and civilian agencies routinely respond to disasters around the world, including large-scale mass casualty events such as the earthquake in Pakistan in 2005, Hurricane Katrina in the United States in 2005, and the earthquake in Haiti in 2010. Potential exists for improved coordination of medical response between civilian and military sectors and for the creation of a planned and practiced interface. Disaster preparedness could be enhanced with more robust disaster education for civilian responders; creation of a database of precredentialed, precertified medical specialists; implementation of a communication bridge; and the establishment of agreements between military and civilian medical/surgical groups in advance of major catastrophic events. PMID:21304048

  18. General Household Emergency Preparedness: A Comparison Between Veterans and Nonveterans

    PubMed Central

    Der-Martirosian, Claudia; Strine, Tara; Atia, Mangwi; Chu, Karen; Mitchell, Michael N.; Dobalian, Aram

    2015-01-01

    Background Despite federal and local efforts to educate the public to prepare for major emergencies, many US households remain unprepared for such occurrences. United States Armed Forces veterans are at particular risk during public health emergencies as they are more likely than the general population to have multiple health conditions. Methods This study compares general levels of household emergency preparedness between veterans and nonveterans by focusing on seven surrogate measures of household emergency preparedness (a 3-day supply of food, water, and prescription medications, a battery-operated radio and flashlight, a written evacuation plan, and an expressed willingness to leave the community during a mandatory evacuation). This study used data from the 2006 through 2010 Behavioral Risk Factor Surveillance System (BRFSS), a state representative, random sample of adults aged 18 and older living in 14 states. Results The majority of veteran and nonveteran households had a 3-day supply of food (88% vs 82%, respectively) and prescription medications (95% vs 89%, respectively), access to a working, battery-operated radio (82% vs 77%, respectively) and flashlight (97% vs 95%, respectively), and were willing to leave the community during a mandatory evacuation (91% vs 96%, respectively). These populations were far less likely to have a 3-day supply of water (61% vs 52%, respectively) and a written evacuation plan (24% vs 21%, respectively). After adjusting for various sociodemographic covariates, general health status, and disability status, households with veterans were significantly more likely than households without veterans to have 3-day supplies of food, water, and prescription medications, and a written evacuation plan; less likely to indicate that they would leave their community during a mandatory evacuation; and equally likely to have a working, battery-operated radio and fiashlight. Conclusion These findings suggest that veteran households appear to be

  19. Addressing Society's Preparedness for the Approaching Solar Maximum

    NASA Astrophysics Data System (ADS)

    Tretkoff, Ernie

    2010-07-01

    As the next solar maximum approaches, increased solar activity could damage technology on which society relies, with potentially serious consequences for national security, aviation, emergency response, communications, navigation, spacecraft, and electric power grids. To discuss the state of preparedness, describe recent progress, and address future needs, approximately 200 researchers and stakeholders from government agencies, academia, and industry, including international participants, met in June at the 2010 Space Weather Enterprise Forum in Washington, D. C. The conference's theme was "Building an informed and resilient society—The decade ahead."

  20. 10 CFR Appendix E to Part 50 - Emergency Planning and Preparedness for Production and Utilization Facilities

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Emergency Planning and Preparedness for Production and Utilization Facilities E Appendix E to Part 50 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Pt. 50, App. E Appendix E to Part 50—Emergency Planning and Preparedness for Production and...

  1. Saudi EMS Students' Perception of and Attitudes toward Their Preparedness for Disaster Management

    ERIC Educational Resources Information Center

    Alrazeeni, Daifallah

    2015-01-01

    Background: Disasters led not only to the loss of life and destruction of public infrastructures, but also resulted in consequent healthcare delivery concerns. Disaster preparedness is considered one of the key steps in emergency management. EMS students had very scanty knowledge, attitude and practices about disaster preparedness and mitigation.…

  2. 3 CFR 9009 - Proclamation 9009 of August 30, 2013. National Preparedness Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9009 of August 30, 2013. National Preparedness Month, 2013 9009 Proclamation 9009 Presidential Documents Proclamations Proclamation 9009 of August 30, 2013 Proc. 9009 National Preparedness Month, 2013By the President of the United States of America A Proclamation Time and again,...

  3. 3 CFR 8986 - Proclamation 8986 of May 24, 2013. National Hurricane Preparedness Week, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8986 of May 24, 2013. National Hurricane Preparedness Week, 2013 8986 Proclamation 8986 Presidential Documents Proclamations Proclamation 8986 of May 24, 2013 Proc. 8986 National Hurricane Preparedness Week, 2013By the President of the United States of America A Proclamation Last...

  4. 78 FR 79081 - Medicare and Medicaid Programs; Emergency Preparedness Requirements for Medicare and Medicaid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ...This proposed rule would establish national emergency preparedness requirements for Medicare- and Medicaid-participating providers and suppliers to ensure that they adequately plan for both natural and man-made disasters, and coordinate with federal, state, tribal, regional, and local emergency preparedness systems. It would also ensure that these providers and suppliers are adequately......

  5. Ready for University? A Cross-National Study of Students' Perceived Preparedness for University

    ERIC Educational Resources Information Center

    Jansen, Ellen P. W. A.; van der Meer, Jacques

    2012-01-01

    Students' preparedness for higher education is seen as one of the main factors affecting first-year attrition or study success. In this paper we report on a cross-national study in which students' preparedness for university was measured "before" students commenced their study at a university in New Zealand or in the Netherlands. This…

  6. The "Uncanny" Character of Race: An Exploration of UK Preparedness through Youth Performance

    ERIC Educational Resources Information Center

    Chakrabarty, Namita

    2011-01-01

    Performance is a key tool in emergency preparedness and the rehearsal of professional response, simultaneously raising questions about the practice of cultural assumptions in this context. Usually the actors in preparedness exercises are civil servants who perform the work of the nihilistic imagination in often-apocalyptic fictional scenarios,…

  7. Comparison of School Counselors and School Social Workers: Performance of Tasks and Perceived Preparedness

    ERIC Educational Resources Information Center

    Feldman, Matthew

    2010-01-01

    This study compares the professional roles of school counselors and school social workers in terms of the frequency of performing various practice tasks, feelings of preparedness to perform various practice tasks, discrepancies between frequency of task performance and feelings of preparedness to perform said tasks, and factors that may affect…

  8. 76 FR 18221 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10 (a) (2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  9. 77 FR 37410 - Board of Scientific Counselors, Office of Public Health Preparedness and Response; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Public Health Preparedness and Response; Meeting In accordance with section 10 (a) (2) of the Federal... Prevention (CDC), and the Director, Office of Public Health Preparedness and Response (OPHPR), concerning... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  10. 77 FR 20823 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH...

  11. 78 FR 40743 - Board of Scientific Counselors, Office of Public Health Preparedness and Response, Board of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... Public Health Preparedness and Response, Board of Scientific Counselors (BSC OPHPR) In accordance with... Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response (OPHPR... Address Contact Person for More Information: Marquita Black, Office of Science and Public Health...

  12. 76 FR 76416 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  13. 76 FR 53474 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10 (a)(2) of the Federal..., Office of Public Health Preparedness and Response (OPHPR), concerning strategies and goals for the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  14. Natural Hazard Preparedness in an Auckland Community: Child and Community Perceptions

    ERIC Educational Resources Information Center

    Bolton, Patricia; Dirks, Kim; Neuwelt, Pat

    2014-01-01

    Community engagement in natural hazard preparedness is crucial to ensure sustainable initiatives. Children are important members of communities, and can actively contribute to community preparedness. This article presents research undertaken with 11- to 12-year-old students from a school in Auckland, New Zealand, and leaders associated with the…

  15. The Difficult Transition? Teaching, Research, Service: Examining the Preparedness of Communication Faculty Entering the Academe

    ERIC Educational Resources Information Center

    Whitfield, Toni Selena; Hickerson, Corey

    2013-01-01

    This study, based on a survey of graduate students seeking employment, examines the categories and levels of preparedness of new professors/instructors as they enter academe. Preparedness was examined in several ways--specifically knowledge about higher education requirements and their preparation for teaching, advising, and service in the field…

  16. Practitioners' & LIS Students' Perceptions on Preparedness in the New York Metropolitan Area

    ERIC Educational Resources Information Center

    Creel, Stacy L.; Pollicino, Elizabeth B.

    2012-01-01

    This paper discusses the results of a study that focused on the perceived preparedness of recent graduates. Fifty-five St. John's University MLS students surveyed 348 practitioners in public libraries (181) and school libraries (167) concerning perceived preparedness of recent MLS graduates for the realities of working in libraries. The overriding…

  17. Emergency Preparedness as Public Pedagogy: The Absent-Presence of Race in "Preparing for Emergencies"

    ERIC Educational Resources Information Center

    Preston, John; Avery, Barry; Chakrabarty, Namita; Edmonds, Casey

    2011-01-01

    Emergency preparedness can be considered to be a form of lifelong learning and public pedagogy with implications for race equality. The paper is based on an ESRC project "Preparedness pedagogies and race: an interdisciplinary approach" considering the policy process around the construction of the "Preparing for Emergencies" (PFE) campaign. This…

  18. 3 CFR 8830 - Proclamation 8830 of May 25, 2012. National Hurricane Preparedness Week, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Hurricane Preparedness Week, 2012 8830 Proclamation 8830 Presidential Documents Proclamations Proclamation 8830 of May 25, 2012 Proc. 8830 National Hurricane Preparedness Week, 2012By the President of the United States of America A Proclamation Every year, hurricanes put communities at risk of...

  19. 3 CFR 8523 - Proclamation 8523 of May 20, 2010. National Hurricane Preparedness Week, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Hurricane Preparedness Week, 2010 8523 Proclamation 8523 Presidential Documents Proclamations Proclamation 8523 of May 20, 2010 Proc. 8523 National Hurricane Preparedness Week, 2010By the President of the United States of America A Proclamation Each year during hurricane season, Americans living in...

  20. 3 CFR 8700 - Proclamation 8700 of August 31, 2011. National Preparedness Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8700 of August 31, 2011. National... August 31, 2011 Proc. 8700 National Preparedness Month, 2011By the President of the United States of... sectors. Individuals also play a vital role in securing our country. The National Preparedness...

  1. A Study of Emergency Preparedness of U.S. Colleges and Universities

    ERIC Educational Resources Information Center

    Connolly, Maureen

    2011-01-01

    This study provides a framework for institutions of higher education to measure to what extent their emergency preparedness plans align with the National Response Framework (NRF). The author used alignment with the five principles of the NRF as a proxy to measure emergency preparedness at colleges and universities and to answer the following…

  2. Situated Preparedness: The Negotiation of a Future Catastrophic Earthquake in a California University

    ERIC Educational Resources Information Center

    Baker, Natalie Danielle

    2013-01-01

    This dissertation examines disaster preparedness as engaged at a large university in southern California using inductive research and grounded theory data collection and analysis methods. The thesis consists of three parts, all addressing the problem of disaster preparedness as enacted in this at-risk context. I use in-depth interviews, archival…

  3. Experiences of final year nursing students in their preparedness to become registered nurses.

    PubMed

    Carlson, S; Kotzé, W J; van Rooyen, D

    2005-11-01

    The objectives of this study were: firstly, to explore and describe the experiences of final year nursing students relating to how they experience their preparedness to fulfil the role of professional nurse; secondly, to explore and describe the experiences of novice professional nurses in the role of professional nurse; finally, to generate a model which will assist the final year nursing student to become a professional nurse. A theory-generative, qualitative, explorative, descriptive and contextual research design was utilized to reach the objectives of the study. Results indicated that final year nursing students experience a lack of confidence to take on the responsibilities of professional nursing. The results are displayed in table form and discussed in the article. This abstract forms part of a bigger study that addresses the professional maturity of the novice professional nurse for the practice of nursing. PMID:16450561

  4. Use of simulated patients and reflective video analysis to assess occupational therapy students' preparedness for fieldwork.

    PubMed

    Giles, Amanda K; Carson, Nancy E; Breland, Hazel L; Coker-Bolt, Patty; Bowman, Peter J

    2014-01-01

    Educators must determine whether occupational therapy students are adequately prepared for Level II fieldwork once they have successfully completed the didactic portion of their coursework. Although studies have shown that students regard the use of video cameras and simulated patient encounters as useful tools for assessing professional and clinical behaviors, little has been published in the occupational therapy literature regarding the practical application of simulated patients or reflective video analysis. We describe a model for a final Comprehensive Practical Exam that uses both simulated patients and reflective video analysis to assess student preparedness for Level II fieldwork, and we report on student perceptions of these instructional modalities. We provide recommendations for designing, implementing, and evaluating simulated patient experiences in light of existing educational theory. PMID:25397940

  5. Flash Mob Science - Increasing Seismic Hazard Awareness and Preparedness in Oregon

    NASA Astrophysics Data System (ADS)

    Hoffman, J. S.; Lownsbery, D. S.

    2015-12-01

    Living in a region of imminent threat of a magnitude-9.0 (M­­­w ≈ ­9) earthquake is a daily reality for the millions of people predicted to be directly affected by a full rupture of the Cascadia Subduction Zone (CSZ), a fault line extending for hundreds of miles off the western coast of North America. Many coastal residents and visitors will also be affected by the tsunami caused by the rupture. How can the scientific community effectively communicate with those who are unaware of the threat and unprepared to respond? We are studying the effects of a novel approach to science outreach we have called Flash Mob Science. You have probably seen examples of flash mobs staging dynamic musical and dance routines to unsuspecting audiences. Similarly, Flash Mob Science takes the challenging (and often avoided) topic of earthquake and tsunami awareness and preparedness to unsuspecting audiences. However, Flash Mob Science seeks to move beyond having an audience of observers by engaging others as participants who enact important roles in an unfolding drama. We simulate the effects of seismic and tsunami events (e.g., prolonged surface shaking, falling debris, repeated tsunami surges) and model best practices in response (e.g., "Drop, Cover, Hold On" and moving quickly to high ground). True to the general flash mob model, when the Cascadia event inevitably does occur, it will come suddenly, and everyone affected will unavoidably be involved as actors in a real-life drama of immense scale. We seek to embed the learning of basic understandings and practices for an actual Cascadia event in a very small-scale, memorable, and sometimes even humorous, dramatization. We present here the lessons we have learned in the background, planning, and implementation of Flash Mob Science. We highlight the successes, limitations, and preliminary results evaluating the effectiveness of this outreach in developing learners' understandings and preparedness in an Oregon community affected by

  6. State of Virtual Reality Based Disaster Preparedness and Response Training

    PubMed Central

    Hsu, Edbert B.; Li, Yang; Bayram, Jamil D.; Levinson, David; Yang, Samuel; Monahan, Colleen

    2013-01-01

    The advent of technologically-based approaches to disaster response training through Virtual Reality (VR) environments appears promising in its ability to bridge the gaps of other commonly established training formats. Specifically, the immersive and participatory nature of VR training offers a unique realistic quality that is not generally present in classroom-based or web-based training, yet retains considerable cost advantages over large-scale real-life exercises and other modalities and is gaining increasing acceptance. Currently, numerous government departments and agencies including the U.S. Department of Homeland Security (DHS), the Centers for Disease Control and Prevention (CDC) as well as academic institutions are exploring the unique advantages of VR-based training for disaster preparedness and response. Growing implementation of VR-based training for disaster preparedness and response, conducted either independently or combined with other training formats, is anticipated. This paper reviews several applications of VR-based training in the United States, and reveals advantages as well as potential drawbacks and challenges associated with the implementation of such training platform. PMID:23653102

  7. The zombie thermographer apocalypse preparedness 101: zombie thermographer pandemic

    NASA Astrophysics Data System (ADS)

    Colbert, Fred

    2013-05-01

    Fact: The U.S Government Centers for Disease Control and Prevention (CDC), Office of Public Health Preparedness and Response, rather remarkably has dedicated part of their web site to" Zombie Preparedness". See: http://www.cdc.gov/phpr/zombies.htm for more information. This is a tongue-incheek campaign with messages to engage audiences with the hazards of unpreparedness. The CDC director, U.S. Assistant Surgeon General Ali S. Khan (RET), MD, MPH notes, "If you are generally well equipped to deal with a zombie apocalypse you will be prepared for a hurricane, pandemic, earthquake, or terrorist attack. Make a plan, and be prepared!" (CDC Website, April 26th, 2013). Today we can make an easy comparison between the humor that the CDC is bringing to light, and what is actually happening in the Thermographic Industry. It must be acknowledge there are "Zombie Thermographers" out there. At times, it can be observed from the sidelines as a pandemic apocalypse attacking the credibility and legitimacy of the science and the industry that so many have been working to advance for over 30 years. This paper outlines and explores the trends currently taking place, the very real risks to facility plant, property, and human life as a result, and the strategies to overcome these problems.

  8. Tabletop scenarios for realism in bioterrorism and threat preparedness.

    PubMed

    Abraham, Rachel T; Walls, Richard T; Fischer, Mark; Markovic-Reed, Sandra; Solovieva, Tatiana I; Russell, Floyd K; Ducatman, Alan M

    2012-01-01

    Five realistic tabletop scenarios were designed to facilitate threat preparedness training of Medical, Public Health, Nursing, Emergency Services, Mental Health, Allied Health, and Pharmacy personnel. Training scenarios were (1) student contaminates lettuce (Act) in a state university with Shigella sonnei (Agent), (2) dismissed athlete contaminates ice (Act) at the basketball tournament with Escherichia coli (Agent), (3) workers fail to report abandoned backpacks (Act) at a state fair that contain smallpox virus (Agent), (4) terrorists expose county residents (Act) to Pneumonic plague bacterium (Agent), and (5) infected birds expose field-trip participants (Act) to Avian influenza virus (Agent). Evaluation of the tabletops yielded positive ratings of educational outcomes in these domains: well-structured, organized, plausible, realistic, engaging, on-target, useful, and multidisciplinary. Attendees with previous blended-learning courses on bioterrorism and threat preparedness enhanced performance in the tabletop exercises. Evaluative data indicated a new level of competence and self-confidence about being part of a coordinated, local-level, interdisciplinary response. PMID:23472535

  9. Perceptions of disaster preparedness among older people in South Korea.

    PubMed

    Yoo, Myoungran; Lee, Mijung; Tullmann, Dorothy

    2016-03-01

    Older people are a major vulnerable population. During disasters, given their physical frailty, lower social status, loss of medications and medical care, the vulnerability of older people increases. The purpose of this study was to examine the perceptions of older people in Korea on various aspects of disaster preparedness to better understand their special needs and to facilitate appropriate disaster planning. The study was qualitative and used focus group interviews with 12 older people in one major city and one rural area of South Korea. Four themes were identified by the analysis of the interviews: defenceless state, reality of accepting limitations, strong will to live, importance of disaster preparedness governmental efforts for the older people. Findings indicated that preparation of shelters and transportation was critical to help older people survive in times of disasters and suggested that there should be active involvement of the government in terms of disaster planning, managing and preparing older people for disasters. In addition, healthy older people can be assets to disaster relief efforts by providing practical and emotional support for the most fragile older people. Older people can also provide knowledge of their special needs to the government to improve their disaster response policy. PMID:26179452

  10. A Counter-IED Preparedness Methodology for Large Event Planning

    SciTech Connect

    Payne, Patricia W; Koch, Daniel B

    2011-01-01

    Since 2009, Oak Ridge National Laboratory (ORNL) has been involved in a project sponsored by the Department of Homeland Security Science and Technology Directorate aimed at improving preparedness against Improvised Explosive Devices (IED) at large sporting events. Led by the University of Southern Mississippi (USM) as part of the Southeast Region Research Initiative, the project partners have been developing tools and methodologies for use by security personnel and first responders at sports stadiums. ORNL s contribution has been to develop an automated process to gather and organize disparate data that is usually part of an organization s security plan. The organized data informs a table-top exercise (TTX) conducted by USM using additional tools developed by them and their subcontractors. After participating in several pilot TTXs, patterns are beginning to emerge that would enable improvements to be formulated to increase the level of counter-IED preparedness. This paper focuses on the data collection and analysis process and shares insights gained to date.

  11. Public health preparedness and response capacity inventory validity study.

    PubMed

    Costich, Julia Field; Scutchfield, F Douglas

    2004-01-01

    The Centers for Disease Control and Prevention's Public Health Practice Program Office has issued a Public Health Preparedness and Response Capacity Inventory to help state and local public health systems assess their progress towards achievement of the critical capacities and benchmarks specified in the federal Supplemental Funds for Public Health Preparedness and Response for Bioterrorism. The criterion validity of the capacity inventory was assessed by comparing selected state and local agency responses with documentation provided by the agencies to corroborate their answers. Content validity assessment took the form of a mailed survey that also identified the most important questions from the perspective of a separate set of state and local officials. Responses generally upheld the validity of the capacity inventory, although circumstantial threats to validity were identified in the testing process. The instrument's use has been reported to the Centers for Disease Control and Prevention by approximately half the states and over 800 local public health entities. An interactive electronic version includes a scoring mechanism that allows agencies to judge progress towards the critical capacities and benchmarks over time. PMID:15253518

  12. Mental health and psychosocial support aspects in disaster preparedness: Nepal.

    PubMed

    Acharya, Lumeshor; Upadhya, Kapil Dev; Kortmann, Frank

    2006-12-01

    To improve mental health care in Nepal, a National Mental Health Policy, Strategy and Plan of Action was approved by the Government in 1997. Nepal has high vulnerability to natural disasters compounded by a prolonged violent civil conflict affecting almost all districts of the country. Floods, landslides and earthquakes are the most regularly occurring disasters in Nepal. There is a Health Sector Emergency and Disaster Response Plan of the Ministry of Health, but mental health and psychosocial relief is not adequately addressed in this plan. In 2003 guidelines on best public health practices in emergencies for district health workers was developed in which the minimum standard and indicators include aspects of mental and social aspects of health. The experience of the complex emergency in April 2005 showed that in general the emergency preparedness plan has not been prepared well enough, but on the other hand the health system was able to cope quite well because of past training. Further strengthening of the mental health and psychosocial aspects of disaster preparedness is strongly recommended. PMID:17162702

  13. Bioterrorism preparedness and response in European public health institutes.

    PubMed

    Coignard, B

    2001-11-01

    The terrorist attacks on 11 September 2001 and the deliberate release of anthrax in the United States had consequences for public health not only there, but also in Europe. Europe's public health systems had to manage numerous postal materials possibly contaminated with anthrax. Our survey aimed to document the response of European public health institutes to recent bioterrorist events to identify the gaps that need to be addressed; 18 institutes from 16 countries participated in this Euroroundup. Bioterrorist threats in Europe were hoaxes only, and should be considered as a "preparedness exercise" from which three lessons can be drawn. Firstly, because of inadequate preparedness planning and funding arrangements, Europe was not ready in October 2001 to respond to bioterrorism. Secondly, although European institutes reacted quickly and adapted their priorities to a new type of threat, they need adequate and sustained support from national governments to maintain their overall capacity. Thirdly, the recent crisis demonstrated the need for increased investment in epidemiology training programmes and the establishment of a technical coordination unit for international surveillance and outbreak response in the European Union. PMID:11891386

  14. Preparedness for a smallpox pandemic in Japan: public health perspectives.

    PubMed

    Nishiyama, Yasumasa; Matsukuma, Susumu; Matsumura, Takuya; Kanatani, Yasuhiro; Saito, Tomoya

    2015-04-01

    Smallpox is an acute, febrile, contagious disease caused by the Variola virus, which is a member of the Poxviridae family. Until the 1970s, smallpox had been a pandemic disease for more than 3000 years, endemic in tropical and developing areas and periodically epidemic worldwide. The World Health Organization declared smallpox to be completely eradicated in 1980 as the result of global vaccination efforts. At that time, all routine vaccination programs were terminated, given the success of thismonumental eradication. Although smallpox remains fully eradicated, uncertainty exists regarding the possibility of recurrent smallpox outbreaks. At the end of the Cold War, concerns regarding unstable international security and the feasibility of terrorism with weapons of mass destruction have been highlighted. The potential threat of intentional release of smallpox has forced regional health authorities to reconsider their political landscape and create preparedness plans to protect the community in the event of biological attacks. Here we present current countermeasures to this biological threat in Japan and discuss methods for strengthening public health preparedness both domestically and internationally. These methods include infection control, vaccination policy, and international partnerships to help deter or contain a contagious smallpox pandemic. PMID:26060873

  15. Tsunami Preparedness Along the U.S. West Coast (video)

    USGS Publications Warehouse

    Filmed and edited by: Loeffler, Kurt; Gesell, Justine

    2010-01-01

    Tsunamis are a constant threat to the coasts of our world. Although tsunamis are infrequent along the West coast of the United States, it is possible and necessary to prepare for potential tsunami hazards to minimize loss of life and property. Community awareness programs are important, as they strive to create an informed society by providing education and training. This video about tsunami preparedness along the West coast distinguishes between a local tsunami and a distant event and focuses on the specific needs of each region. It offers guidelines for correct tsunami response and community preparedness from local emergency managers, first-responders, and leading experts on tsunami hazards and warnings, who have been working on ways of making the tsunami affected regions safer for the people and communities on a long-term basis. This video was produced by the US Geological Survey (USGS) in cooperation with the California Emergency Management Agency (CalEMA), Oregon Department of Geology and Mineral Industries (DOGAMI), Washington Emergency Management Division (EMD), Marin Office of Emergency Services, and Pacific Gas and Electric (PG&E).

  16. [Preparedness of health system in Israel for mass emergencies].

    PubMed

    Navrátil, Václav; Navrátil, Leoš

    2015-01-01

    The vast number of outbreaks of tension on the planet shows that it is impossible to underestimate the preparation level of population protection in emergencies. The possibility of a terrorist attack, including the use of particularly toxic or biological substances cannot be excluded or totally prevented at this point. In fact, there may not only be a terrorist attack. Rampant population migration increases the risk of the transmission of infectious diseases, even to considerable distances from the states where the epidemiological situation might not be completely under control. The current state of the Czech healthcare system in terms of preparedness for mass emergencies is insufficient and requires prompt correction, though not through hastily adopted measures. Ideally, looking into the success of the Israeli preparedness system, where the public has been exposed to high levels of threat from a variety of causes for decades, could greatly aid the Czech Republic in moving forward effectively. The number of victims of terrorist attacks there outpaces 10000, a fact that shows Israel is experienced in responding to emergency incidents. PMID:26311029

  17. Barriers to Disaster Preparedness among Medical Special Needs Populations

    PubMed Central

    Meyer, Leslie; Vatcheva, Kristina; Castellanos, Stephanie; Reininger, Belinda

    2015-01-01

    A medical special needs (MSN) assessment was conducted among 3088 respondents in a hurricane prone area. The sample was female (51.7%), Hispanic (92.9%), aged >45 years (51%), not insured for health (59.2%), and with an MSN (33.2%). Barriers to preparedness were characterized for all households, including those with inhabitants reporting MSN ranging from level 0 (mild) to level 4 (most severe). Multivariable logistic regression tested associations between hurricane preparedness and barriers to evacuation by level of MSN. A significant interaction effect between number of evacuation barriers and MSN was found. Among households that reported individuals with level 0 MSN, the odds of being unprepared increased 18% for each additional evacuation barrier [OR = 1.18, 95% CI (1.08, 1.30)]. Among households that reported individuals with level 1 MSN, the odds of being unprepared increased 29% for each additional evacuation barrier [OR = 1.29, 95% CI (1.11, 1.51)]. Among households that reported individuals with level 3 MSN, the odds of being unprepared increased 68% for each additional evacuation barrier [OR = 1.68, 95% CI (1.21, 1.32)]. MSN alone did not explain the probability of unpreparedness, but rather MSN in the presence of barriers helped explain unpreparedness. PMID:26389107

  18. Revisiting blood transfusion preparedness: experience from the Bam earthquake response.

    PubMed

    Abolghasemi, Hassan; Radfar, Mohammad H; Tabatabaee, Morteza; Hosseini-Divkolayee, Nasim S; Burkle, Frederick M

    2008-01-01

    Blood transfusion plays a critical role in the provision of medical care for disasters due to man-made and natural hazards. Although the short-term increase in blood donations following national disasters is well-documented, some aspects of blood transfusion during disasters remain under study. The 2003 earthquake in Bam, Iran resulted in the death of >29,000 people and injured 23,000. In total, 108,985 blood units were donated, but only 21,347 units (23%) actually were distributed to hospitals around the country. Kerman Province, the site of the disaster, received 1,231 (1.3%) of the donated units in the first four days after the disaster. The Bam experience revealed crucial missteps in the development of a post-event strategy for blood product management, and led to the development of a detailed disaster preparedness and response plan that addresses issues of donation, distribution, communication, transportation, and coordination. The current plan requires the Iranian Blood Transfusion Organization to convene a disaster task force immediately as the main coordinator of all disaster preparedness and response activities. PMID:19189607

  19. Avian influenza and pandemic influenza preparedness in Hong Kong.

    PubMed

    Lam, Ping Yan

    2008-06-01

    Avian influenza A H5N1 continues to be a major threat to global public health as it is a likely candidate for the next influenza pandemic. To protect public health and avert potential disruption to the economy, the Hong Kong Special Administrative Region Government has committed substantial effort in preparedness for avian and pandemic influenza. Public health infrastructures for emerging infectious diseases have been developed to enhance command, control and coordination of emergency response. Strategies against avian and pandemic influenza are formulated to reduce opportunities for human infection, detect pandemic influenza timely, and enhance emergency preparedness and response capacity. Key components of the pandemic response include strengthening disease surveillance systems, updating legislation on infectious disease prevention and control, enhancing traveller health measures, building surge capacity, maintaining adequate pharmaceutical stockpiles, and ensuring business continuity during crisis. Challenges from avian and pandemic influenza are not to be underestimated. Implementing quarantine and social distancing measures to contain or mitigate the spread of pandemic influenza is problematic in a highly urbanised city like Hong Kong as they involved complex operational and ethical issues. Sustaining effective risk communication campaigns during interpandemic times is another challenge. Being a member of the global village, Hong Kong is committed to contributing its share of efforts and collaborating with health authorities internationally in combating our common public health enemy. PMID:18618061

  20. The public health dashboard: a surveillance model for bioterrorism preparedness.

    PubMed

    Foldy, Seth L; Biedrzycki, Paul A; Baker, Bevan K; Swain, Geoffrey R; Howe, Donna S; Gieryn, Douglas; Barthell, Edward N; Pemble, Kim R

    2004-01-01

    The City of Milwaukee Health Department piloted a short-term, near real-time syndromic surveillance and communication tool by using an existing secure regional Internet infrastructure. Voluntary, active syndromic case reporting by hospital Emergency Departments was combined with other data streams, including clinical laboratory reports of communicable disease, hospital emergency room diversions, ambulance runs, medical examiner reports of unusual or suspicious deaths, poison control and nursing hotline call volumes, and pharmacy over-the-counter sales. These data were aggregated into a "Surveillance Dashboard" format that was used to communicate community syndromic health trends to hospitals, Emergency Departments, and other providers using a secure Internet technology. Emergency Departments at 8 area hospitals reported a total of 314 cases meeting syndromic criteria from 26,888 patient encounters. Participants were satisfied with data entry and communications. All participating Emergency Departments received e-mail and text pager alerts sent by the Milwaukee Health Department. No unexplained findings or suggestions of an early outbreak were reported through syndrome surveillance for the 4-week duration of the project. Similar surveillance and communications systems could provide multiple benefits to Emergency Department workflow and management, as well as to public health and emergency response. PMID:15253519

  1. Perioperatively acquired disorders of coagulation

    PubMed Central

    Grottke, Oliver; Fries, Dietmar; Nascimento, Bartolomeu

    2015-01-01

    Purpose of review To provide an overview of acquired coagulopathies that can occur in various perioperative clinical settings. Also described are coagulation disturbances linked to antithrombotic medications and currently available strategies to reverse their antithrombotic effects in situations of severe hemorrhage. Recent findings Recent studies highlight the link between low fibrinogen and decreased fibrin polymerization in the development of acquired coagulopathy. Particularly, fibrin(ogen) deficits are observable after cardiopulmonary bypass in cardiac surgery, on arrival at the emergency room in trauma patients, and with ongoing bleeding after child birth. Regarding antithrombotic therapy, although new oral anticoagulants offer the possibility of efficacy and relative safety compared with vitamin K antagonists, reversal of their anticoagulant effect with nonspecific agents, including prothrombin complex concentrate, has provided conflicting results. Specific antidotes, currently being developed, are not yet licensed for clinical use, but initial results are promising. Summary Targeted hemostatic therapy aims to correct coagulopathies in specific clinical settings, and reduce the need for allogeneic transfusions, thus preventing massive transfusion and its deleterious outcomes. Although there are specific guidelines for reversing anticoagulation in patients treated with antiplatelet agents or warfarin, there is currently little evidence to advocate comprehensive recommendations to treat drug-induced coagulopathy associated with new oral anticoagulants. PMID:25734869

  2. Foodborne listeriosis acquired in hospitals.

    PubMed

    Silk, Benjamin J; McCoy, Morgan H; Iwamoto, Martha; Griffin, Patricia M

    2014-08-15

    Listeriosis is characterized by bacteremia or meningitis. We searched for listeriosis case series and outbreak investigations published in English by 2013, and assessed the strength of evidence for foodborne acquisition among patients who ate hospital food. We identified 30 reports from 13 countries. Among the case series, the median proportion of cases considered to be hospital-acquired was 25% (range, 9%-67%). The median number of outbreak-related illnesses considered to be hospital-acquired was 4.0 (range, 2-16). All patients were immunosuppressed in 18 of 24 (75%) reports with available data. Eight outbreak reports with strong evidence for foodborne acquisition in a hospital implicated sandwiches (3 reports), butter, precut celery, Camembert cheese, sausage, and tuna salad (1 report each). Foodborne acquisition of listeriosis among hospitalized patients is well documented internationally. The number of listeriosis cases could be reduced substantially by establishing hospital policies for safe food preparation for immunocompromised patients and by not serving them higher-risk foods. PMID:24846635

  3. The National Data Centre Preparedness Exercise NPE 2012 - Waveform data analysis results

    NASA Astrophysics Data System (ADS)

    Gestermann, Nicolai; Hartmann, Gernot; Ross, Ole; Ceranna, Lars; Bönnemann, Christian

    2013-04-01

    The National Data Centre Preparedness Exercises simulate a fictitious violation of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) and are conducted by NDCs (National Data Centres) for NDCs with the aim to increase the awareness and preparedness of their duties. These exercises are regularly performed with different scenarios and key aspects. They help to evaluate the effectiveness of procedures applied at NDCs, as well as the quality, completeness, and usefulness of IDC (International Data Centre) products. The NPE 2012 has been organized and coordinated by the control team at the German NDC on behalf of the remaining NDCs and with support from the CTBT- Organization. A seismic event from REB (Reviewed Event Bulletin) was selected as an internal source of a fictitious release of iodine and radioxenon. Additionally, xenon releases at two background sources were included. The exercise started with the notification of hypothetical radionuclide concentrations detected at IMS stations (International Monitoring System. The internal release scenario was kept undisclosed for participants during the exercise. Therefore one main task of the exercise was the identification of the seismic source event. Atmospheric Transport Modeling in backward mode was required to confine the possible source region and find candidate waveform events from REB. The analysis of xenon isotopic ratios gives additional information about the source characteristics and the event timing. Seismological characteristics of the remaining candidate events was investigated in detail and combined with associated infrasound detections to discriminate between natural seismic events and explosions. Spectral behaviors and source characteristics derived from seismic recordings at IMS stations were compared with events from various clusters associated with mining activities. Individual analysis steps are presented and challenges towards possible source identification for the NPE 2012 as well.

  4. Broadly protective adenovirus-based multivalent vaccines against highly pathogenic avian influenza viruses for pandemic preparedness.

    PubMed

    Vemula, Sai V; Ahi, Yadvinder S; Swaim, Anne-Marie; Katz, Jacqueline M; Donis, Ruben; Sambhara, Suryaprakash; Mittal, Suresh K

    2013-01-01

    Recurrent outbreaks of H5, H7 and H9 avian influenza viruses in domestic poultry accompanied by their occasional transmission to humans have highlighted the public health threat posed by these viruses. Newer vaccine approaches for pandemic preparedness against these viruses are needed, given the limitations of vaccines currently approved for H5N1 viruses in terms of their production timelines and the ability to induce protective immune responses in the absence of adjuvants. In this study, we evaluated the feasibility of an adenovirus (AdV)-based multivalent vaccine approach for pandemic preparedness against H5, H7 and H9 avian influenza viruses in a mouse model. Replication-defective AdV vectors expressing hemagglutinin (HA) from different subtypes and nucleoprotein (NP) from one subtype induced high levels of humoral and cellular immune responses and conferred protection against virus replication following challenge with H5, H7 and H9 avian influenza virus subtypes. Inclusion of HA from the 2009 H1N1 pandemic virus in the vaccine formulation further broadened the vaccine coverage. Significantly high levels of HA stalk-specific antibodies were observed following immunization with the multivalent vaccine. Inclusion of NP into the multivalent HA vaccine formulation resulted in the induction of CD8 T cell responses. These results suggest that a multivalent vaccine strategy may provide reasonable protection in the event of a pandemic caused by H5, H7, or H9 avian influenza virus before a strain-matched vaccine can be produced. PMID:23638099

  5. Increasing awareness and preparedness by an exhibition and studying the effect of visuals

    NASA Astrophysics Data System (ADS)

    Charrière, Marie; Bogaard, Thom; Malet, Jean-Philippe; Mostert, Erik

    2013-04-01

    Damages caused by natural hazards can be reduced not only by protection, management and intervention activities, but also by information and communication to improve awareness and preparedness of local communities and tourists. Risk communication is particularly crucial for mountainous areas, such as the Ubaye Valley (France), as they are affected by multiple hazards and are particularly sensitive to the potential effects of climate and socio-economic changes which may increase the risk associated with natural hazards significantly. An exhibition is a powerful tool to communicate with the general public. It allows1: (1) targeting specific audiences, (2) transmitting technical and scientific knowledge using a suitable language, (3) anchoring the collective memory of past events, (4) visualize and emotionalize the topic of natural hazards, (5) strengthening the communication between peers, and (6) highlighting local resources and knowledge. In addition to these theoretical advantages, an exhibition may fulfill the requirements of a community. In the Ubaye Valley (France), this tool was proposed by the stakeholders themselves to increase awareness and preparedness of the general public. To meet this demand, the exhibition was designed following three general topics: (1) the natural phenomena and their potential consequences on the elements at risk, (2) the management and protection measures (individual and collective) and (3) the evolution of events and knowledge throughout past up to the present and the anticipation of the future situations. Besides being a real risk communication practice, this exhibition will be the setting for an extensive research project studying the effect of the use of visualization tools on the awareness and preparedness of a community. A wide range of visuals (photos, videos, maps, models, animations, multimedia, etc.) will present many dimensions of locally occurring natural hazards and risk problems. The aim of the research is (1) to

  6. Acquired immunodeficiency syndrome: neuroradiologic findings.

    PubMed

    Kelly, W M; Brant-Zawadzki, M

    1983-11-01

    Central nervous system complications depicted by CT in ten patients with acquired immunodeficiency syndrome are described. Three patients had multifocal intra-axial enhancing lesions representing atypical brain abscesses (two with toxoplasmosis, one with candidiasis). A fourth patient with multifocal "ring" lesions whose biopsy was interpreted as suggestive of toxoplasmosis responded poorly to treatment. Following his death three months later of Pneumocystis carinii pneumonia, autopsy revealed primary intracerebral immunoblastic lymphoma. One patient had Kaposi sarcoma involving the right frontal lobe (seen as an enhancing mass on the CT scan). CT findings in the remaining five patients revealed mild to moderate enlargement of cerebrospinal fluid spaces (including ventricles and basal cisternae) as a result of cryptococcal meningitis in three patients and "aseptic" meningitis in two. The two patients in whom early biopsy confirmed toxoplasmosis responded well to anti-infective therapy, resulting in dramatic clinical recoveries. PMID:6622693

  7. Bejel: acquirable only in childhood?

    PubMed

    Rothschild, Bruce M; Rothschild, Christine; Naples, Virginia; Billard, Michel; Panero, Barbara

    2006-10-01

    Bejel clearly has a long history in the Middle East and the Sudan, but was it transmitted to Europe? As the major manifestation of bejel is presence of periosteal reaction in 20-40% of afflicted populations, absence of significant population frequency of periosteal reaction in Europe would exclude that diagnosis. Examination of skeletal populations from continental Europe revealed no significant periosteal reaction at the time of and immediately subsequent to the Crusades. Thus, there is no evidence for bejel in Europe, in spite of clear contact (the mechanism of bejel transmission in children) between warring groups, at least during the Crusades. This supports the hypothesis that bejel is a childhood-acquired disease and apparently cannot be contracted in adulthood. PMID:17049474

  8. Lymphoma in acquired generalized lipodystrophy.

    PubMed

    Brown, Rebecca J; Chan, Jean L; Jaffe, Elaine S; Cochran, Elaine; DePaoli, Alex M; Gautier, Jean-Francois; Goujard, Cecile; Vigouroux, Corinne; Gorden, Phillip

    2016-01-01

    Acquired generalized lipodystrophy (AGL) is a rare disease thought to result from autoimmune destruction of adipose tissue. Peripheral T-cell lymphoma (PTCL) has been reported in two AGL patients. We report five additional cases of lymphoma in AGL, and analyze the role of underlying autoimmunity and recombinant human leptin (metreleptin) replacement in lymphoma development. Three patients developed lymphoma during metreleptin treatment (two PTCL and one ALK-positive anaplastic large cell lymphoma), and two developed lymphomas (mycosis fungoides and Burkitt lymphoma) without metreleptin. AGL is associated with high risk for lymphoma, especially PTCL. Autoimmunity likely contributes to this risk. Lymphoma developed with or without metreleptin, suggesting metreleptin does not directly cause lymphoma development; a theoretical role of metreleptin in lymphoma progression remains possible. For most patients with AGL and severe metabolic complications, the proven benefits of metreleptin on metabolic disease will likely outweigh theoretical risks of metreleptin in lymphoma development or progression. PMID:25864863

  9. Emergency Preparedness in the 10-Mile Emergency Planning Zone Surrounding Nuclear Power Plants

    PubMed Central

    Adalja, Amesh A.; Sell, Tara Kirk; Ravi, Sanjana J.; Minton, Katie; Morhard, Ryan

    2015-01-01

    Objectives Each of the nuclear power plants in the US is encircled by an Emergency Planning Zone (EPZ). Within each EPZ, government officials, utility professionals, emergency managers, and public health practitioners collectively conduct extensive planning, exercises, and outreach to better protect their communities in the event of a nuclear accident. Our objective was to conduct a cross-sectional study of off-site public health preparedness within EPZs to better understand the dynamics of nuclear preparedness and uncover lessons for all-hazards preparedness. Methods Using a qualitative, interview-based method, we consulted 120 county emergency managers, state health preparedness officers, state radiation health officials, and industry officials from 17 EPZs in ten different states. Results Interviewees reflected that EPZ emergency preparedness is generally robust, results from strong public-private partnership between nuclear plants and emergency management agencies, and enhances all-hazard preparedness. However, there exist a few areas which merit further study and improvement. These areas include cross-state coordination, digital public communication, and optimizing the level of public education within EPZs. Conclusions This first-of-its-kind study provides a cross-sectional snapshot of emergency preparedness in the 10-mile EPZ surrounding nuclear power plants. PMID:26692825

  10. The Study to Improve Tsunami Preparedness Education in Turkey

    NASA Astrophysics Data System (ADS)

    Sakamoto, Mayumi; Tanırcan, Gülüm; Kaneda, Yoshiyuki; Puskulcu, Seyhun; Kumamoto, Kunihiko

    2016-04-01

    Compared to its long history on disastrous earthquakes, disaster education history in Turkey is rather short. It has just started with an initiative of Disaster Preparedness Education Unit of Bogazici University (BU/DPEU) after 1999 Kocaeli Earthquake. Training modules and materials on disaster preparedness were prepared both for students, teachers and community. Regarding to the school education, the Ministry of National Education (MoNE) reformed their education plan in 2003, and disaster education became one of eight focused components for primary-middle education. In 2011-2014 MoNE had conducted "School-based Disaster Education Project" in collaboration with Japan International Cooperation Agency (JICA). The majority of the school education materials focus more on earthquake and there are very few education programs on tsunami. Within the MarDiM (Earthquake and Tsunami Disaster Mitigation in the Marmara Region and Disaster Education in Turkey) project between Turkey and Japan a multidisciplinary engineering research as well as development of disaster education, tsunami education booklet and video were newly developed in 2015. In order to investigate students' knowledge natural disasters and disaster preparedness with focus on tsunami, a questionnaire based survey was conducted. The survey aims to clarify following questions: 1) how students obtain natural disaster information, 2) how students prepare for natural disaster, 3) knowledge on tsunami (hazard mechanism, evacuation behavior, historical disaster). The study was conducted by BU/DPEU in 2015 and 375 students answered the questionnaire. Results showed that students have more interest on earthquake, flood, tsunami and landslide followed it. Most students have heard about tsunami and the school is a key resource of their information. They know relatively well about tsunami mechanism, however, they have less knowledge on tsunami evacuation behavior and tsunami history in Turkey. In order to let students have

  11. Art of Disaster Preparedness in European Union: a Survey on the Health Systems

    PubMed Central

    Djalali, Ahmadreza; Della Corte, Francesco; Foletti, Marco; Ragazzoni, Luca; Ripoll Gallardo, Alba; Lupescu, Olivera; Arculeo, Chris; von Arnim, Götz; Friedl, Tom; Ashkenazi, Michael; Fischer, Philipp; Hreckovski, Boris; Khorram-Manesh, Amir; Komadina, Radko; Lechner, Konstanze; Patru, Cristina; Burkle, Frederick M.; Ingrassia, Pier Luigi

    2014-01-01

    Introduction: Naturally occurring and man-made disasters have been increasing in the world, including Europe, over the past several decades. Health systems are a key part of any community disaster management system. The success of preparedness and prevention depends on the success of activities such as disaster planning, organization and training. The aim of this study is to evaluate health system preparedness for disasters in the 27 European Union member countries. Method: A cross-sectional analysis study was completed between June-September 2012. The checklist used for this survey was a modified from the World Health Organization toolkit for assessing health-system capacity for crisis management. Three specialists from each of the 27 European Union countries were included in the survey. Responses to each survey question were scored and the range of preparedness level was defined as 0-100%, categorized in three levels as follows: Acceptable; Transitional; or Insufficient. Results: Response rate was 79.1%. The average level of disaster management preparedness in the health systems of 27 European Union member states was 68% (Acceptable). The highest level of preparedness was seen in the United Kingdom, Luxemburg, and Lithuania. Considering the elements of disaster management system, the highest level of preparedness score was at health information elements (86%), and the lowest level was for hospitals, and educational elements (54%). Conclusion: This survey study suggests that preparedness level of European Union countries in 2012 is at an acceptable level but could be improved. Elements such as hospitals and education and training suffer from insufficient levels of preparedness. The European Union health systems need a collective strategic plan, as well as enough resources, to establish a comprehensive and standardized disaster management strategy plan. A competency based training curriculum for managers and first responders is basic to accomplishing this goal

  12. 7 CFR 926.10 - Acquire.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.10 Acquire. Acquire means to obtain cranberries by any means whatsoever for the purpose of handling cranberries....

  13. 7 CFR 926.10 - Acquire.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.10 Acquire. Acquire means to obtain cranberries by any means whatsoever for the purpose of handling cranberries....

  14. 7 CFR 926.10 - Acquire.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.10 Acquire. Acquire means to obtain cranberries by any means whatsoever for the purpose of handling cranberries....

  15. 7 CFR 926.10 - Acquire.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.10 Acquire. Acquire means to obtain cranberries by any means whatsoever for the purpose of handling cranberries....

  16. After 9/11: priority focus areas for bioterrorism preparedness in hospitals.

    PubMed

    Murphy, Jenifer K

    2004-01-01

    Following the terrorist attacks of September 11, 2001, bioterrorism preparedness was a priority in hospitals, but it did not remain a priority. As a result, hospitals are still unprepared to deal with the effects of a bioterrorist attack. The government has provided initial funding to state and local governments for bioterrorism preparedness; however, much of this money has yet to reach hospitals. With the inadequate funding available to hospitals, four initial measures must be focused on. These focus areas are community involvement, hospital staff education, information technology and disease surveillance improvement, and additional equipment and staff acquisition. Hospitals should also make bioterrorism-preparedness planning a regional effort. PMID:15328657

  17. Coping With Client Death: How Prepared Are Home Health Aides and What Characterized Preparedness?

    PubMed Central

    van Riesenbeck, Isabelle; Boerner, Kathrin; Barooah, Adrita; Burack, Orah R.

    2016-01-01

    This study explored the experiences of 80 home health aides (HHAs) whose client died within the last two months. Data collection involved comprehensive semi-structured in-person interviews to try to better understand characteristics of HHAs and their clients associated with preparedness for death. Among those, personal end-of-life (EOL) care preferences of HHAs and having knowledge of preferences and decisions regarding client’s EOL care showed significant links to preparedness. Findings suggest that HHAs’ preparedness for client death could be enhanced both by addressing their personal views on EOL care and by providing more information about the client’s EOL care plans. PMID:26496432

  18. Stakeholders' experiences with US hospital emergency preparedness--Part 2.

    PubMed

    Cagliuso, Nicholas V

    This study examined, via qualitative phenomenology, important stakeholders' experiences with US hospital emergency preparedness, finding that their experiences varied from positive and effective to frustrating, time-consuming and inefficient. The findings centred on four themes: the importance of funding; collaboration, communication and coordination; the role of government; and hospital leadership buy-in. Together, these findings suggest that issues such as a lack of performance metrics, insufficient funding, inadequate surge capacity, confusing federal guidelines and accreditation requirements and an overall lack of coordination in hospitals' abilities to manage emergency incidents continue to plague the US healthcare system. Exploring, and now understanding, these experiences can support the field in maintaining elements that work and recognising and applying solutions to its short-comings. This is the second of two papers on the subject, the first of which appeared in a previous issue of this journal, examining the study's methodological approach, data analysis, main results and implications for practice. PMID:26591933

  19. Preparedness for Threat of Chikungunya in the Pacific

    PubMed Central

    Hoy, Damian; Horwood, Paul F.; Ropa, Berry; Hancock, Thane; Guillaumot, Laurent; Rickart, Keith; Frison, Pascal; Pavlin, Boris; Souares, Yvan

    2014-01-01

    Chikungunya virus (CHIKV) caused significant outbreaks of illness during 2005–2007 in the Indian Ocean region. Chikungunya outbreaks have also occurred in the Pacific region, including in Papua New Guinea in 2012; New Caledonia in April 2013; and Yap State, Federated States of Micronesia, in August 2013. CHIKV is a threat in the Pacific, and the risk for further spread is high, given several similarities between the Pacific and Indian Ocean chikungunya outbreaks. Island health care systems have difficulties coping with high caseloads, which highlights the need for early multidisciplinary preparedness. The Pacific Public Health Surveillance Network has developed several strategies focusing on surveillance, case management, vector control, laboratory confirmation, and communication. The management of this CHIKV threat will likely have broad implications for global public health. PMID:25062306

  20. Updates on disaster preparedness and progress in disaster relief.

    PubMed

    Pollak, Andrew N; Born, Christopher T; Kamal, Robin N; Adashi, Eli Y

    2012-01-01

    Immediately after the January 2010 earthquake in Haiti, many private citizens, governmental and nongovernmental organizations, and medical associations struggled to mount an effective humanitarian aid response. The experiences of these groups have led to changes at their institutions regarding disaster preparedness and response to future events. One of the main challenges in a humanitarian medical response to a disaster is determining when to end response efforts and return responsibility for delivery of medical care back to the host nation. For such a transition to occur, the host nation must have the capacity to deliver medical care. In Haiti, minimal capacity to deliver such care existed before the earthquake, making subsequent transition difficult. If successful, several initiatives proposed to improve disaster response and increase surgical capacity in Haiti could be deployed to other low- and middle-income countries. PMID:22865138

  1. Pharmacy Leader’s Role in Hospital Emergency Preparedness Planning

    PubMed Central

    Bell, Christopher; Daniel, Sarah

    2014-01-01

    The Director’s Forum column is designed to guide pharmacy leaders in establishing patient-centered services in hospitals and health systems. Environmental disasters and terrorist attacks demonstrate that it is imperative for both a hospital and community to have an emergency preparedness plan. The goal of this article is to provide health-system pharmacy leaders with a practical approach in developing an emergency operations plan (EOP) that can be activated in the event of a disaster. Pharmacy leaders should (1) review government and community disaster responses and understand the movement of drug supply for each response, (2) create a pharmacy disaster plan, (3) list the essential medications and determine their inventory levels, and (4) establish a staff training program to enhance understanding and implementation of the EOP. If successfully developed and executed, a hospital pharmacy department’s EOP has a high rating of success in meeting patient-centered needs in the unforeseen event of a disaster PMID:24958947

  2. Southern state radiological emergency preparedness and response agencies

    SciTech Connect

    Not Available

    1988-11-01

    This Report provides information on the state agencies assigned to radioactive materials transportation incidents in 16 Southern States Energy Board member states. For each, the report lists the agencies with primary authority for preparedness and response, their responsibilities and personnel within the agencies who can offer additional information on their radioactive materials transportation programs. The report also lists each state's emergency team members and its laboratory and analytical capabilities. Finally, the governor's designee for receiving advance notification of high-level radioactive materials and spent fuel shipments under 10 CFR Parts 71 and 73 of the US Nuclear Regulatory Commission's regulations is listed for each state. Part 71 requires prenotification for large quantity radioactive waste shipments. Part 73 addresses prenotification for spent nuclear reactor fuel shipments.

  3. Southern state radiological emergency preparedness and response agencies

    SciTech Connect

    Not Available

    1988-11-01

    This Report provides information on the state agencies assigned to radioactive materials transportation incidents in 16 Southern States Energy Board member states. For each, the report lists the agencies with primary authority for preparedness and response, their responsibilities and personnel within the agencies who can offer additional information on their radioactive materials transportation programs. The report also lists each state`s emergency team members and its laboratory and analytical capabilities. Finally, the governor`s designee for receiving advance notification of high-level radioactive materials and spent fuel shipments under 10 CFR Parts 71 and 73 of the US Nuclear Regulatory Commission`s regulations is listed for each state. Part 71 requires prenotification for large quantity radioactive waste shipments. Part 73 addresses prenotification for spent nuclear reactor fuel shipments.

  4. Safety and emergency preparedness considerations for geotechnical field operations

    SciTech Connect

    Wemple, R.P.

    1989-04-01

    The GEO Energy Technology Department at Sandia National Laboratories is involved in several remote-site drilling and/or experimental operations each year. In 1987, the Geothermal Research Division of the Department developed a general set of Safe Operating Procedures (SOPs) that could be applied to a variety of projects. This general set is supplemented by site-specific SOPs as needed. Effective field operations require: integration of safety and emergency preparedness planning with overall project planning, training of field personnel and inventorying of local emergency support resources, and, developing a clear line of responsibility and authority to enforce the safety requirements. Copies of SOPs used in recent operations are included as examples of working documents for the reader.

  5. Public health preparedness for chemical incidents in Europe.

    PubMed

    Kello, Dinko

    2003-06-01

    In response to the attack of 11 September 2001 on the USA, World Health Organization (WHO), Regional Office for Europe took immediate steps in order to be able to assist countries in case of a terrorist attack. Among other things, WHO organised a series of different consultations with international organisations, government representatives and experts in order to assess the state of preparedness at the national and international levels, to identify the main problems and to make recommendations. The problems were addressed in the context of possible public health consequences, regardless of whether such an incident derived from a deliberate act or a naturally occurring event. This overview gives a brief account of presentation made at the European Union "First Civil Protection Forum", which was held in Brussels in November 2002, and which served as a basis for defining the EU priorities and actions to make Europe a safer place to live. PMID:14679666

  6. Hospital preparedness for possible nonconventional casualties: an Israeli experience.

    PubMed

    Schreiber, Shaul; Yoeli, Naomi; Paz, Gedalia; Barbash, Gabriel I; Varssano, David; Fertel, Nurit; Hassner, Avi; Drory, Margalit; Halpern, Pinchas

    2004-01-01

    Since 9/11, hospitals and health authorities have been preparing medical response in case of various mass terror attacks. The experience of Tel Aviv Sourasky Medical Center in treating suicide-bombing mass casualties served, in the time leading up to the war in Iraq, as a platform for launching a preparedness program for possible attacks with biological and chemical agents of mass destruction. Adapting Quarantelli's criteria on disaster mitigation to the "microinfrastructure" of the hospital, and including human behavior experts, we attempted to foster an interactive emergency management process that would deal with contingencies stemming from the potential hazards of chemical and biological (CB) weapons. The main objective of our work was to encourage an organization-wide communication network that could effectively address the contingent hazards unique to this unprecedented situation. A stratified assessment of needs, identification of unique dangers to first responders, and assignment of team-training sessions paved the way for program development. Empowerment through leadership and resilience training was introduced to emergency team leaders of all disciplines. Focal subject matters included proactive planning, problem-solving, informal horizontal and vertical communication, and coping through stress-management techniques. The outcome of this process was manifested in an "operation and people" orientation supporting a more effective and compatible emergency management. The aim of article is to describe this process and to point toward the need for a broad-spectrum view in such circumstances. Unlike military units, the civilian hospital staff at risk, expected to deal with CB casualties, requires adequate personal consideration to enable effective functioning. Issues remain to be addressed in the future. We believe that collaboration and sharing of knowledge, information, and expertise beyond the medical realm is imperative in assisting hospitals to expedite

  7. Planning guidance for the Chemical Stockpile Emergency Preparedness Program

    SciTech Connect

    Shumpert, B.L.; Watson, A.P.; Sorensen, J.H.

    1995-02-01

    This planning guide was developed under the direction of the U.S. Army and the Federal Emergency Management Agency (FEMA) which jointly coordinate and direct the development of the Chemical Stockpile Emergency Preparedness Program (CSEPP). It was produced to assist state, local, and Army installation planners in formulating and coordinating plans for chemical events that may occur at the chemical agent stockpile storage locations in the continental United States. This document provides broad planning guidance for use by both on-post and off-post agencies and organizations in the development of a coordinated plan for responding to chemical events. It contains checklists to assist in assuring that all important aspects are included in the plans and procedures developed at each Chemical Stockpile Disposal Program (CSDP) location. The checklists are supplemented by planning guidelines in the appendices which provide more detailed guidance regarding some issues. The planning guidance contained in this document will help ensure that adequate coordination between on-post and off-post planners occurs during the planning process. This planning guide broadly describes an adequate emergency planning base that assures that critical planning decisions will be made consistently at every chemical agent stockpile location. This planning guide includes material drawn from other documents developed by the FEMA, the Army, and other federal agencies with emergency preparedness program responsibilities. Some of this material has been developed specifically to meet the unique requirements of the CSEPP. In addition to this guidance, other location-specific documents, technical studies, and support studies should be used as needed to assist in the planning at each of the chemical agent stockpile locations to address the specific hazards and conditions at each location.

  8. Identification and analysis of obstacles in bioterrorism preparedness and response

    NASA Astrophysics Data System (ADS)

    Sincavage, Suzanne Michele

    The focus of this study was to identify and analyze the obstacles to bioterrorism preparedness and response facing emergency management agencies and public authorities. In order to establish the limits of this discussion, the obstacles will examine a combined conceptual framework of public health, environmental security and social response. The interdisciplinary characteristics of this framework are ideal for addressing the issue of bioterrorism because of its simultaneous impact, which encompasses the complex interrelationships that pertain to public health and national security and social response. Based on a review of literature, the obstacles presented range from the absence of an effective surveillance system for biological terrorism related diseases to the inadequate training of first responders in bioterrorism preparedness and the difficult challenges of a mass casualty situation and the intense pressures associated with the crisis response. Furthermore, the impending reality of bioterrorism will further illustrate a close examination of the characteristics and management of three major biowarfare agents---anthrax, plague and smallpox. Finally, to provide a realistic understanding of the impact of bioterrorism, three case studies of actual events and two hypothetical scenarios will be discussed. Specifically, the discussion will provide the following three unconventional terrorist attacks: the recent anthrax attacks of 2001, the Aum Shinrikyo's attack of the Tokyo subway in 1995, and the Rajneeshees' use of salmonella poisoning in 1994. The inclusion of the hypothetical scenarios of two massive outbreaks of smallpox and anthrax will be presented to illuminate the seriousness and magnitude of the threat of bioterrorism and the probable consequences of failing to overcome the obstacles presented in this study. The importance of this research cannot be overemphasized, the threat is undeniably serious, and the potential for biological agents to cause devastating

  9. Acquired immune deficiency syndrome (AIDS).

    PubMed

    1987-02-01

    The International Planned Parenthood Medical Advisory Panel has developed recommendations to assist family planning associations in playing a more active role in the prevention and control of acquired immunodeficiency syndrome (AIDS). Of primary importance is an effective program of information and education aimed at communicating the following facts: AIDS is a fatal disease for which there is no cure; AIDS is spread by sexual intercourse, contaminated blood, and contaminated needles; an infected woman can transmit AIDS to her fetus during pregnancy; a monogamous sexual relationship is the surest way to avoid AIDS infection; condom use is good protection; an infected person can look and feel well, yet still be able to transmit the AIDS virus; and AIDS is not spread by ordinary contact with an infected person. Family planning associations should include information on AIDS in all existing IEC projects, as well as develop new materials. Among the target audiences for IEC activities are family planning workers, family planning clients, and the general public including youth, teachers, parents, employers, and national leaders. Special attention should be given to high-risk groups such as homosexual and bisexual men, hemophiliacs, male and female prostitutes, clients of sexually transmitted disease clinics, people with many sexual partners, illegal users of intravenous drugs, and the sexual partners of those in any of these groups. Wide promotion of condom use is a priority activity for family planning organizations. PMID:12340977

  10. Infections Acquired in the Garden.

    PubMed

    Cunha, Cheston B; Cunha, Burke A

    2015-10-01

    Gardening is a wonderful pastime, and the garden is a very peaceful place to enjoy one's vacation. However, the garden may be a treacherous place for very young or compromised hosts when one takes into account the infectious potential residing in the soil, as well as the insect vectors on plants and animals. Even normal hosts may acquire a variety of infections from the soil, animals, or animal-related insect bites. The location of the garden, its natural animal and insect inhabitants, and the characteristics of the soil play a part in determining its infectious potential. The most important factor making the garden an infectious and dangerous place is the number and interaction of animals, whether they are pets or wild, that temporarily use the garden for part of their daily activities. The clinician should always ask about garden exposure, which will help in eliminating the diagnostic possibilities for the patient. The diagnostic approach is to use epidemiological principles in concert with clinical clues, which together should suggest a reasonable list of diagnostic possibilities. Organ involvement and specific laboratory tests help further narrow the differential diagnosis and determine the specific tests necessary to make a definitive diagnosis. PMID:26542044

  11. Emergency Preparedness with People Who Sign: Toward the whole community approach.

    PubMed

    Cripps, Jody H; Cooper, Sheryl B; Austin, Elizabeth N

    2016-01-01

    The concept of the "whole community" involves including everyone in the community in preparing for emergencies, including members of often-overlooked groups. Deaf people who sign are one example of this type of group. An innovative model based on the whole community approach, Emergency Preparedness with People Who Sign (EPPS), is introduced in this article. This model focuses on members of the deaf community directly training first responders using a variety of techniques for effective communication and cultural understanding to achieve safety for all. This model was developed and field tested by a university Deaf Studies program through student service-learning activities and faculty involvement including on-site role-playing. Through the reciprocal awareness training for both professionals and community members, deaf individuals become actively empowered to participate in developing culturally and linguistically sensitive public safety services. Response to the concurrent training of first responders and deaf community members has been positive, and it is hoped that this model can be replicated with deaf people and first responders in other locations, as well as with other often-overlooked groups. PMID:27108919

  12. School nurse online emergency preparedness training: an analysis of knowledge, skills, and confidence.

    PubMed

    Elgie, Robert; Sapien, Robert; Fullerton, Lynne; Moore, Brian

    2010-10-01

    The objective of this study was to evaluate the effectiveness of a computer-assisted emergency preparedness course for school nurses. Participants from a convenience sample (52) of school nurses from New Mexico were randomly assigned to intervention or control groups in an experimental after-only posttest design. Intervention group participants completed 15 online emergency preparedness training modules followed by posttests, and control group participants completed the posttests without taking the training modules. Tests measured emergency preparedness with written exams, confidence surveys, and skills performance in videotaped scenarios; the videotaped scenarios were scored by Pediatric Emergency Medicine physicians blinded to whether the participants were in the intervention or control group. The intervention group participants scored significantly higher in tests of knowledge and skills than control group participants. Confidence Survey scores did not differ significantly. The online training modules are a valuable resource for improving school nurse emergency preparedness knowledge and skills but may not affect participants' confidence. PMID:20501914

  13. 78 FR 39304 - Agency Information Collection Activities: Proposed Collection; Comment Request; FEMA Preparedness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Proposed Collection; Comment Request; FEMA Preparedness Grants: Operation Stonegarden (OPSG) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency, as part of...

  14. Preparedness of Hospitals in North of Iran to Deal With Disasters

    PubMed Central

    Amiri, Mohammad; Chaman, Reza; Raei, Mehdi; Nasrollahpour Shirvani, Seiyed Davoud; Afkar, Abolhasan

    2013-01-01

    Introduction Preparedness of hospital has a major impact on their optimal and satisfactory performance. This study aimed to investigate the preparedness of the hospitals to deal with disasters. Case Presentation This cross-sectional study was carried in 2011 and all of the hospitals which were located in the northern areas of Iran were investigated through the census method. The data collection instruments were self-administered Managers’ Awareness Questionnaire (40 items) and a 141-item checklist. The mean percentage score of hospitals in management of the unanticipated disasters program in the hospital was good. The mean score of managers’ awareness of the hospital status was moderate. With the increase in managers’ awareness, the preparedness of the hospitals significantly increased (r = 0.73, P < 0.001). Conclusions The findings showed the moderate preparedness of the hospitals in the Northern provinces to deal with disasters. PMID:24349752

  15. 78 FR 66938 - Board of Scientific Counselors, Office of Public Health Preparedness and Response, Board of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... Public Health Preparedness and Response, Board of Scientific Counselors (BSC OPHPR) Cancellation This... More Information: Marquita Black, Executive Assistant, Office of Science and Public Health Practice... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  16. 75 FR 26773 - Public Readiness and Emergency Preparedness Act Countermeasures Injury Compensation Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Public Readiness and Emergency Preparedness... CICP administers the compensation program authorized by the Public Readiness and Emergency...

  17. 77 FR 59001 - Fee for Services To Support FEMA's Offsite Radiological Emergency Preparedness Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... SECURITY Federal Emergency Management Agency Fee for Services To Support FEMA's Offsite Radiological Emergency Preparedness Program AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) is establishing a fiscal year (FY) 2014 hourly rate...

  18. 75 FR 19985 - Fee for Services To Support FEMA's Offsite Radiological Emergency Preparedness Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... SECURITY Federal Emergency Management Agency Fee for Services To Support FEMA's Offsite Radiological Emergency Preparedness Program AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) has established a fiscal year (FY) 2010 hourly rate...

  19. Unveiling the Truth about Nurses' Personal Preparedness for Disaster Response: A Pilot Study.

    PubMed

    Nash, Tracy Jeanne

    2015-01-01

    Although nurses are essential caregivers in disaster response, many are not prepared personally to report to the workplace during disaster situations. An online disaster preparedness education intervention to support personal readiness is described in this pilot study. PMID:26863707

  20. The role of information technology in emergency preparedness by local health departments: a literature review.

    PubMed

    Nguh, Jonas

    2014-01-01

    Ever since the terrorist attacks of 9/11, the federal government increased funding for emergency preparedness. However, the literature continues to document several areas of weaknesses in public health emergency management by local health departments (LHD). This literature review discusses the role of information technology (IT) for emergency preparedness by LHDs. The focus areas for this review include evaluating the strategic management of IT by LHD, evaluation of the adoption and implementation of IT in emergency management, and assessing LHD's capacity and capability for emergency preparedness. Findings reveal that LHDs face significant challenges in the utilization of IT for emergency preparedness purposes such as weak capacity and capabilities, lack of structured planning and program implementation, and limited resources. Implications from this review include the development of "best practices," increased funding for IT infrastructure, and the establishment of strategic management framework for IT initiatives. PMID:25069026

  1. Building community resilience: business preparedness lessons in the case of Adapazarı, Turkey.

    PubMed

    Orhan, Ezgi

    2016-01-01

    The lack of attention paid to businesses in disaster management systems from the standpoint of state policies hampers efforts to build community resilience. This paper examines, therefore, the extent of business preparedness for disasters. Empirical research was conducted in Adapazarı, Turkey, 13 years after the İzmit earthquake, which struck the northwest of the country on 17 August 1999, claiming the lives of some 17,000 people. For the study, 232 firms were selected to inquire about their preparedness before and after the event. It is hypothesised that business preparedness is influenced by the following set of variables: business size; business sector; business age; financial condition prior to the disaster; occupancy tenure; market range; education level; and previous disaster experience. In line with the findings of the research, a policy framework is constructed to rationalise the allocation of resources for building resilience at the aggregate level by facilitating business preparedness. PMID:26271477

  2. The connections place: a job preparedness program for individuals with borderline personality disorder.

    PubMed

    Elliott, Beth; Konet, Richard J

    2014-01-01

    This article describes a pilot project that provided a job preparedness program specifically designed for individuals who suffer from borderline personality disorder (BPD). The program called "The Connections Place" or "TCP" was based on a 16-week curriculum that focused on both helping individuals with BPD overcome emotional barriers to employment and preparing these individuals to enter/reenter the work world. Ninety clients were enrolled in the pilot project that was conducted over three and one-half years. Almost all participants (n = 54) who completed at least 1 month of the program made significant strides in the following areas: obtained employment or achieved a similar goal (48 %), notably improved their job preparedness (22 %), or made some/limited progress toward job preparedness (26 %). These preliminary findings support the potential effectiveness of job preparedness programs targeted to individuals with BPD. PMID:23408295

  3. HNS-MS : Improving Member States preparedness to face an HNS pollution of the Marine System

    NASA Astrophysics Data System (ADS)

    Legrand, Sebastien; Le Floch, Stéphane; Aprin, Laurent; Parthenay, Valérie; Donnay, Eric; Parmentier, Koen; Ovidio, Fabrice; Schallier, Ronny; Poncet, Florence; Chataing, Sophie; Poupon, Emmanuelle; Hellouvry, Yann-Hervé

    2016-04-01

    When dealing with a HNS pollution incident, one of the priority requirements is the identification of the hazard and an assessment of the risk posed to the public and responder safety, the environment and socioeconomic assets upon which a state or coastal community depend. The primary factors which determine the safety, environmental and socioeconomic impact of the released substance(s) relate to their physico-chemical properties and fate in the environment. Until now, preparedness actions at various levels have primarily aimed at classifying the general environmental or public health hazard of an HNS, or at performing a risk analysis of HNS transported in European marine regions. Operational datasheets have been (MIDSIS-TROCS) or are being (MAR-CIS) developed collating detailed, substance-specific information for responders and covering information needs at the first stage of an incident. However, contrary to oil pollution preparedness and response tools, only few decision-support tools used by Member State authorities (Coastguard agencies or other) integrate 3D models that are able to simulate the drift, fate and behaviour of HNS spills in the marine environment. When they do, they usually consider simplified or steady-state environmental conditions. Moreover, the above-mentioned available HNS information is currently not sufficiently detailed or not suitably classified to be used as an input for an advanced HNS support decision tool. HNS-MS aims at developing a 'one-stop shop' integrated HNS decision-support tool that is able to predict the drift, behaviour and Fate of HNS spills under realistic environmental conditions and at providing key product information - drawing upon and in complement to existing studies and databases - to improve the understanding and evaluation of a HNS spill situation in the field and the environmental and safety-related issues at stake. The 3D HNS drift and fate model and decision-support tool will also be useful at the preparedness

  4. Clinicopathological associations of acquired erythroblastopenia

    PubMed Central

    Gunes, Gursel; Malkan, Umit Yavuz; Yasar, Hatime Arzu; Eliacik, Eylem; Haznedaroglu, Ibrahim Celalettin; Demiroglu, Haluk; Sayinalp, Nilgun; Aksu, Salih; Etgul, Sezgin; Aslan, Tuncay; Goker, Hakan; Ozcebe, Osman Ilhami; Buyukasik, Yahya

    2015-01-01

    Introduction: Acquired erythroblastopenia (AE) is a rare clinical situation. It is characterized by the reduction of erythroid precursors in the bone marrow together with the low reticulocyte counts in the peripheral blood. Background: Main secondary causes of AE are drugs, Parvovirus B19 and other infectious reasons, lymphoid and myeloid neoplasia, autoimmune diseases, thymoma and pregnancy. The aim of this study is to assess the frequencies and clinical associations of AE via analyzing 12340 bone marrow samples in a retrospective manner. Material and method: Bone marrow aspirations which were obtained from patients who applied to Hacettepe University Hematology Clinic between 2002 and 2013, were analyzed retrospectively. Results: Thirty four erythroblastopenia cases were found. Patients ranged in age from 16 to 80 years with a median of 38 years. Fifteen patients were men (44%) and nineteen were women (56%). In these patients, detected causes of erythroblastopenia were MDS, idiopathic pure red cell aplasia (PRCA), parvovirus infection, post chemotherapy aplasia, plasma proliferative diseases, copper deficiency due to secondary amyloidosis, fever of unknown origin, hemophagocytic syndrome, enteric fever and legionella pneumonia. We found that between those reasons the most common causes of erythroblastopenia are MDS (17.7%) and idiopathic PRCA (17.7%). Discussion: As a result, erythroblastopenia in the bone marrow may be an early sign of MDS. In those AE cases possibility of being MDS must be kept in mind as it can be mistaken for PRCA. Conclusion: To conclude, in adults MDS without excess blast is one of the most common causes of erythroblastopenia in clinical practice and in case of erythroblastopenia the presence of MDS should be investigated. PMID:26885236

  5. Surface Sampler Arm Acquiring Sample

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Operation of the surface sampler in obtaining Martian soil for Viking 2's molecular analysis experiment last Saturday (September 25) was closely monitored by one of the Lander cameras because of the precision required in trenching the small area--8 by 9 inches-surrounded by rocks. Dubbed 'Bonneville Salt Flats,' the exposure of thin crust appeared unique in contrast with surrounding materials and became a prime target for organic analysis in spite of potential hazards. Large rock in foreground is 8 inches high. At left, the sampler scoop has touched the surface, missing the rock at upper left by a comfortable 6 inches, and the backhoe has penetrated the surface about one-half inch. The scoop was then pulled back to sample the desired point and (second photo) the backhoe furrowed the surface pulling a piece of thin crust toward the spacecraft. The initial touchdown and retraction sequence was used to avoid a collision between a rock in the shadow of the arm and a plate joining the arm and scoop. The rock was cleared by 2 to 3 inches. The third picture was taken 8 minutes after the scoop touched the surface and shows that the collector head has acquired a quantity of soil. With surface sampler withdrawn (right), the foot-long trench is seen between the rocks. The trench is three inches wide and about 1 1/2 to 2 inches deep. The scoop reached to within 3 inches of the rock at far end of trench. Penetration appears to have left a cavernous opening roofed by the crust and only about one inch of undisturbed crust separates the deformed surface and the rock.

  6. Hospital Nurse Staffing and Public Health Emergency Preparedness: Implications for Policy

    PubMed Central

    McHugh, Matthew D.

    2010-01-01

    Hospital restructuring policies and an impending nursing workforce shortage have threatened the nation’s emergency preparedness. Current emergency response plans rely on sources of nurses that are limited and overestimated. A national investment in nursing education and workforce infrastructure, as well as incentives for hospitals to efficiently maximize nurse staffing, are needed to ensure emergency preparedness in the United States. This review highlights the challenges of maintaining hospital nursing surge capacity and policy implications of a nursing shortage. PMID:20840714

  7. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND... Statements of Smaller Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired....

  8. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND...-06 Real estate operations acquired or to be acquired. If, during the period for which...

  9. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND...-06 Real estate operations acquired or to be acquired. If, during the period for which...

  10. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND...-06 Real estate operations acquired or to be acquired. If, during the period for which...

  11. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND... Statements of Smaller Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired....

  12. Co-Evolution of Social Learning and Evolutionary Preparedness in Dangerous Environments.

    PubMed

    Lindström, Björn; Selbing, Ida; Olsson, Andreas

    2016-01-01

    Danger is a fundamental aspect of the lives of most animals. Adaptive behavior therefore requires avoiding actions, objects, and environments associated with danger. Previous research has shown that humans and non-human animals can avoid such dangers through two types of behavioral adaptions, (i) genetic preparedness to avoid certain stimuli or actions, and (ii) social learning. These adaptive mechanisms reduce the fitness costs associated with danger but still allow flexible behavior. Despite the empirical prevalence and importance of both these mechanisms, it is unclear when they evolve and how they interact. We used evolutionary agent-based simulations, incorporating empirically based learning mechanisms, to clarify if preparedness and social learning typically both evolve in dangerous environments, and if these mechanisms generally interact synergistically or antagonistically. Our simulations showed that preparedness and social learning often co-evolve because they provide complimentary benefits: genetic preparedness reduced foraging efficiency, but resulted in a higher rate of survival in dangerous environments, while social learning generally came to dominate the population, especially when the environment was stochastic. However, even in this case, genetic preparedness reliably evolved. Broadly, our results indicate that the relationship between preparedness and social learning is important as it can result in trade-offs between behavioral flexibility and safety, which can lead to seemingly suboptimal behavior if the evolutionary environment of the organism is not taken into account. PMID:27487079

  13. Interdisciplinary approach to all-hazards preparedness: are you ready? How do we know?

    PubMed

    Levy, Leonard A; Rokusek, Cecilia F; Bragg, Sally M; Howell, James T

    2009-03-01

    The Center for Bioterrorism and All-Hazards Preparedness (CBAP) at Nova Southeastern University College of Osteopathic Medicine is part of the National Education Strategy Team supported by the Assistant Secretary for Preparedness and Response. It developed and implemented an extensive interdisciplinary community-focused, all-hazards preparedness program as a template for use nationally. CBAP provides discipline-customized education and training experiences in emergency and disaster preparedness using multiple formats. In addition to addressing competencies that all responders must have, the CBAP National Education Strategy Team has special emphasis areas in personal planning, vulnerable and hard-to-reach populations, the employment of "cells" in the community, evidence-based evaluation including a unique casualty objective-structured clinical examination, use of student and faculty and Medical Reserve Corps volunteers, all-hazards preparedness aimed at school children, and programs addressing campus violence. CBAP emphasizes that all-hazards preparedness is an academic discipline that necessitates those trained have periodic updates to maintain their currency. PMID:19202400

  14. Preparedness for Natural Disasters Among Older US Adults: A Nationwide Survey

    PubMed Central

    Rubenstein, Linda M.; Wallace, Robert B.

    2015-01-01

    Objectives. We sought to determine natural disaster preparedness levels among older US adults and assess factors that may adversely affect health and safety during such incidents. Methods. We sampled adults aged 50 years or older (n = 1304) from the 2010 interview survey of the Health and Retirement Study. The survey gathered data on general demographic characteristics, disability status or functional limitations, and preparedness-related factors and behaviors. We calculated a general disaster preparedness score by using individual indicators to assess overall preparedness. Results. Participant (n = 1304) mean age was 70 years (SD = 9.3). Only 34.3% reported participating in an educational program or reading materials about disaster preparation. Nearly 15% reported using electrically powered medical devices that might be at risk in a power outage. The preparedness score indicated that increasing age, physical disability, and lower educational attainment and income were independently and significantly associated with worse overall preparedness. Conclusions. Despite both greater vulnerability to disasters and continuous growth in the number of older US adults, many of the substantial problems discovered are remediable and require attention in the clinical, public health, and emergency management sectors of society. PMID:26313052

  15. Preparedness for Natural Disasters Among Older US Adults: A Nationwide Survey

    PubMed Central

    Rubenstein, Linda M.; Wallace, Robert B.

    2014-01-01

    Objectives. We sought to determine natural disaster preparedness levels among older US adults and assess factors that may adversely affect health and safety during such incidents. Methods. We sampled adults aged 50 years or older (n = 1304) from the 2010 interview survey of the Health and Retirement Study. The survey gathered data on general demographic characteristics, disability status or functional limitations, and preparedness-related factors and behaviors. We calculated a general disaster preparedness score by using individual indicators to assess overall preparedness. Results. Participant (n = 1304) mean age was 70 years (SD = 9.3). Only 34.3% reported participating in an educational program or reading materials about disaster preparation. Nearly 15% reported using electrically powered medical devices that might be at risk in a power outage. The preparedness score indicated that increasing age, physical disability, and lower educational attainment and income were independently and significantly associated with worse overall preparedness. Conclusions. Despite both greater vulnerability to disasters and continuous growth in the number of older US adults, many of the substantial problems discovered are remediable and require attention in the clinical, public health, and emergency management sectors of society. PMID:24432877

  16. Co-Evolution of Social Learning and Evolutionary Preparedness in Dangerous Environments

    PubMed Central

    Lindström, Björn; Selbing, Ida; Olsson, Andreas

    2016-01-01

    Danger is a fundamental aspect of the lives of most animals. Adaptive behavior therefore requires avoiding actions, objects, and environments associated with danger. Previous research has shown that humans and non-human animals can avoid such dangers through two types of behavioral adaptions, (i) genetic preparedness to avoid certain stimuli or actions, and (ii) social learning. These adaptive mechanisms reduce the fitness costs associated with danger but still allow flexible behavior. Despite the empirical prevalence and importance of both these mechanisms, it is unclear when they evolve and how they interact. We used evolutionary agent-based simulations, incorporating empirically based learning mechanisms, to clarify if preparedness and social learning typically both evolve in dangerous environments, and if these mechanisms generally interact synergistically or antagonistically. Our simulations showed that preparedness and social learning often co-evolve because they provide complimentary benefits: genetic preparedness reduced foraging efficiency, but resulted in a higher rate of survival in dangerous environments, while social learning generally came to dominate the population, especially when the environment was stochastic. However, even in this case, genetic preparedness reliably evolved. Broadly, our results indicate that the relationship between preparedness and social learning is important as it can result in trade-offs between behavioral flexibility and safety, which can lead to seemingly suboptimal behavior if the evolutionary environment of the organism is not taken into account. PMID:27487079

  17. A culture of tsunami preparedness and applying knowledge from recent tsunamis affecting California

    NASA Astrophysics Data System (ADS)

    Miller, K. M.; Wilson, R. I.

    2012-12-01

    It is the mission of the California Tsunami Program to ensure public safety by protecting lives and property before, during, and after a potentially destructive or damaging tsunami. In order to achieve this goal, the state has sought first to use finite funding resources to identify and quantify the tsunami hazard using the best available scientific expertise, modeling, data, mapping, and methods at its disposal. Secondly, it has been vital to accurately inform the emergency response community of the nature of the threat by defining inundation zones prior to a tsunami event and leveraging technical expertise during ongoing tsunami alert notifications (specifically incoming wave heights, arrival times, and the dangers of strong currents). State scientists and emergency managers have been able to learn and apply both scientific and emergency response lessons from recent, distant-source tsunamis affecting coastal California (from Samoa in 2009, Chile in 2010, and Japan in 2011). Emergency managers must understand and plan in advance for specific actions and protocols for each alert notification level provided by the NOAA/NWS West Coast/Alaska Tsunami Warning Center. Finally the state program has provided education and outreach information via a multitude of delivery methods, activities, and end products while keeping the message simple, consistent, and focused. The goal is a culture of preparedness and understanding of what to do in the face of a tsunami by residents, visitors, and responsible government officials. We provide an update of results and findings made by the state program with support of the National Tsunami Hazard Mitigation Program through important collaboration with other U.S. States, Territories and agencies. In 2009 the California Emergency Management Agency (CalEMA) and the California Geological Survey (CGS) completed tsunami inundation modeling and mapping for all low-lying, populated coastal areas of California to assist local jurisdictions on

  18. Method for distributed object communications based on dynamically acquired and assembled software components

    NASA Technical Reports Server (NTRS)

    Sundermier, Amy (Inventor)

    2002-01-01

    A method for acquiring and assembling software components at execution time into a client program, where the components may be acquired from remote networked servers is disclosed. The acquired components are assembled according to knowledge represented within one or more acquired mediating components. A mediating component implements knowledge of an object model. A mediating component uses its implemented object model knowledge, acquired component class information and polymorphism to assemble components into an interacting program at execution time. The interactions or abstract relationships between components in the object model may be implemented by the mediating component as direct invocations or indirect events or software bus exchanges. The acquired components may establish communications with remote servers. The acquired components may also present a user interface representing data to be exchanged with the remote servers. The mediating components may be assembled into layers, allowing arbitrarily complex programs to be constructed at execution time.

  19. Risk Perception and the Psychology of Natural Hazard Preparedness

    NASA Astrophysics Data System (ADS)

    Thompson, K. J.; Weber, E. U.

    2014-12-01

    In the preparedness phase of the disaster cycle, willingness to invest resources in prevention and mitigation doesn't depend only on quantitative judgments of the probability of a disaster. People also evaluate the risks of situations in qualitative ways. Psychological studies of risk perception have shown that risk attitudes toward everyday technologies and activities (e.g., electric power, air travel, smoking) can be mapped onto two orthogonal dimensions: how unknown the risks seem, and how dread or severe they feel. Previously, this psychometric approach to risk perception has focused mostly on man-made risks (e.g., Fischhoff et al. 1978, Slovic 1987). In this paper we examine how natural hazards fit into the established unknown/dread risk space. Hazards that are high on the unknown dimension of risk tend to be perceived as having effects that are unknown to science and to the exposed, uncontrollable, and new. Hazards that rank high on the dread/severity dimension are seen as immediate, catastrophic, highly dreaded on a gut level, new, and likely to be fatal. Perceived risk tends to be highest for hazards that are both high on the dread dimension and low on the unknown dimension. We find that weather-related hazards rank lowest on both dimensions: blizzards, heat waves, hailstorms, fog, and ice storms are all feel very known and not particularly dread. The exception for this group is hurricanes and tornadoes, which are viewed as more similar to geophysical hazards and mass movements: high on dread, though not particularly unknown. Two notable outliers are climate change and sea-level rise, which are both considered very unknown (higher than any other natural hazard save sinkholes), and not at all dread (less dread even than fog and dust storms). But when compared with perceptions of technological hazards, nearly every natural hazard ranks as more dread than any technology or activity, including nuclear power. Man-made hazards fall with technologies, rather than

  20. Dealing with Natural Disasters: Preparedness versus Post-Event Response

    NASA Astrophysics Data System (ADS)

    Sitar, N.

    2015-12-01

    Management or mitigation of natural disasters is comprised of two distinct elements: disaster preparedness and disaster response. Fundamentally disasters fall into two categories: 1) those whose timing can be predicted and evaluated in advance, such as hurricanes, floods, tsunamis, or even sea level rise; and 2) those that can be anticipated based on analysis, but their exact timing is unknown, such as earthquakes and landslides. Consequently, the type of response and options available for scientific and engineering consultation are fundamentally different. The common aspects of all natural disasters is that there is evidence of past events either historical or geologic, or both. Thus, given past evidence, scientists and engineers have an opportunity to recommend and guide development and implementation of long term or permanent mitigation measures, such as improving the resiliency of the infrastructure and emergency preparedness. However, the appropriate mitigation measures are very much a function of the type of event. Severe atmospheric events, such as hurricanes, typically can be predicted several days in advance and scientists and engineers have a role in guiding preparation of specific additional, temporary, mitigation measures and selective evacuation, as appropriate. In contrast, while earthquake potential of a given region may be well recognized, the actual timing of the event is an unknown and, consequently, the primary defense is in developing sufficiently resilient infrastructure which can be enhanced with early warning systems. Similarly, the type of damage caused by flooding, e.g. hurricane and tsunami, is significantly different from the type of damage caused by an earthquake in that flooding damage is pervasive affecting large contiguous areas wiping out all infrastructure whereas earthquake or landslide damage tends to be clustered with many elements of infrastructure remaining fully or somewhat operable. This distinction is very important when it

  1. Communicating Tsunami Preparedness Through the Lessons Learned by Survivors

    NASA Astrophysics Data System (ADS)

    Kerlow, I.

    2015-12-01

    Often times science communication is reactive and it minimizes the perceptions of the general public. The Tsunami of New Dreams is a film with the testimonies of survivors of the 2004 Indian Ocean tsunami in Banda Aceh and Aceh Besar in West Sumatra, Indonesia. Production of the film spanned over five years and dozens of interviews, and is based on a unique geographic, demographic and experiential sampling of the local population. This documentary feature film underscores the importance of Earth science and science communication in building sustainable communities. The film is a lesson in survival and sustainability, and it provides a simple but powerful testimony of what to do and what not to do before and during a tsunami. The film also highlights the direct relationship that exists between disaster survival rates and the knowledge of basic Earth science and preparedness facts. We hope that the human stories presented in the film will serve as a strong motivator for general audiences to learn about natural hazards, preparedness, and Earth science. These engaging narratives can touch the minds and hearts of general audiences much faster than technical lectures in a classroom. Some of the testimonies are happy and others are sad, but they all present the wide range of beliefs that influenced the outcomes of the natural disaster. The interviews with survivors are complemented with unique archival footage of the tsunami and unique footage of daily life in Aceh. Hand-drawn illustrations are used to recreate what survivors did immediately after the earthquake, and during the extreme moments when they faced the tsunami waves. Animated visuals, maps and diagrams enhance the understanding of earthquake and tsunami dynamics. The film is a production of the Earth Observatory of Singapore (EOS) in collaboration with the International Center for Aceh and Indian Ocean Studies (ICAIOS) in Banda Aceh, Indonesia. The film is scheduled for release in late 2015. This is a unique

  2. Acquired tracheoesophageal fistula in infancy and childhood.

    PubMed

    Szold, A; Udassin, R; Seror, D; Mogle, P; Godfrey, S

    1991-06-01

    Acquired tracheoesophageal fistula (TEF) is a rare entity in the pediatric age group. We report two pediatric patients with acquired TEF caused by shells of pistachio nuts. In both patients the primary operation did not resolve the problem and a second intervention for recurrent fistula was needed. The special nature of acquired TEF, particularly the one described herein, requires delayed surgical intervention and meticulous separation of the respiratory and alimentary tracts by an intercostal muscle flap. PMID:1941455

  3. Acquired stuttering due to recurrent anaplastic astrocytoma

    PubMed Central

    Peters, Katherine B; Turner, Scott

    2013-01-01

    Acquired (neurogenic) stuttering is a rare phenomenon seen after cerebral infarction or brain injury. Aetiology of this symptom is unclear, but recent evidence supports that it is a disturbance in the left hemispheric neural network involving the interplay between the cortex and basal ganglia. We present the case of a patient who develops acquired stuttering after a recurrence of a right temporoparietal anaplastic astrocytoma (WHO grade III). We also review other cases of acquired stuttering and known anatomical correlates. PMID:24252834

  4. Identifying and tracking plumes affected by an ocean breeze in support of emergency preparedness

    SciTech Connect

    Schwartz, P.E.

    1989-01-01

    To better support emergency preparedness, General Public Utilities (GPU) Nuclear has investigated the frequency of occurrence of the mesoscale ocean breeze at the Oyster Creek Nuclear Generating Station (OCNGS). Through the analysis of the horizontal wind direction and temperature patterns, simple identification of the ocean breeze along with a plume tracking procedure has been developed and incorporated into the site's emergency plant to better safeguard the public with sophisticated protective action measures in case of a nonroutine release. The ocean breeze will frequently produce wind trajectory fields within the plant's emergency planning zone that are different from the normal gradient wind flow. This could greatly alter proper protective action measures since most utilities employ straight-line trajectory air dispersion models. Knowledge of the existence of the ocean breeze and the location of the ocean breeze front become important in the results generated from the straight-line Gaussian dose calculation methodology and in the further development of a more complex dose assessment model. This paper describes the verification and existence of the sea breeze phenomenon and the incorporation of its effects into the OCNGS emergency plan.

  5. Risk communications and the Chemical Stockpile Emergency Preparedness Program

    SciTech Connect

    Vogt, B.M.

    1995-12-31

    One of the greater challenges the Army faces is effectively dealing with the concerns of the public, local officials and the news media on the disposal of aging chemical agents. This paper describes the method developed for the Chemical Stockpile Emergency Preparedness Program (CSEPP). The purpose was to provide a fairly comprehensive document on risk communication research and recommended practices as they related to the CSEPP. Using the communications perspective suggested by Covello and colleagues, the existing practices of communicating risk information about chemical weapons and the associated efforts in emergency planning, storage and eventual disposal are described. Risk communication problems specific to the CSEPP are then examined and described via scenarios. A framework is developed that distinguishes between the major components of risk communication, flow and intent. Within this framework, the research and recommendations are summarized as to direction of flow -- dialogue, or two-way interaction, versus monologue, or one-way communication -- and that of intent -- exchange versus persuasion. The findings and recommendations are synthesized and related to risk events for the CSEPP as posited in the scenarios.

  6. Tropical storm and hurricane recovery and preparedness strategies.

    PubMed

    Goodwin, Bradford S; Donaho, John C

    2010-01-01

    The goal of this article is to present lessons learned from the devastating effects of two specific natural disasters in Texas: Tropical Storm Allison, which flooded Houston in June 2001, and Hurricane Ike, which caused severe damage in Galveston in September 2008. When a disaster is predictable, good predisaster planning can help to save animals lives. However, as disasters are usually not predictable and tend not to follow a script, that plan needs to be easily adaptable and flexible. It should address all aspects of the program and include an evacuation strategy for the animals, data backup, and identification of emergency equipment such as generators and communication systems. Media communication must also be considered as the general public may become emotional about animal-related issues; adverse attention and public scrutiny can be expected if animals die. The psychological impact of the disaster on the lives of those it directly affects may require attention and accommodation in the postdisaster recovery period. Following an overview of each disaster we describe plans for recovery, impacts on research, business continuity programs, and planning and preparation strategies developed against future natural disasters. Long-term planning includes building design as an important factor in protecting both the animals and the research equipment. Lessons learned include successful responses, evaluation for improvements, and preparedness plans and procedures to guard against future disaster-related destruction or loss of facilities, research programs, and animal lives. PMID:20375433

  7. Stakeholders' experiences with US hospital emergency preparedness: Part 1.

    PubMed

    Cagliuso, Nicholas V

    This study examined, via qualitative pheno-menology, important stakeholders' experiences with US hospital emergency preparedness, finding that their experiences varied from positive and effective to frustrating, time-consuming and inefficient. The findings centred on four themes: the importance of funding; collaboration, communication and coordination; the government's role; and hospital leadership buy-in. Together, these findings suggest that issues such as a lack of performance metrics, insufficient funding, inadequate surge capacity, confusing federal guidelines and accreditation requirements and an overall lack of coordination in hospitals' abilities to manage emergency incidents continue to plague the US healthcare system. Exploring and understanding these experiences can support the field in maintaining elements that work and recognising and applying solutions to its shortcomings. This is the first of two papers on the subject, providing background on the topic, the study's purpose, research design and a review of salient literature. The second paper, in a forthcoming issue of this journal, will examine the study's methodological approach, data analysis, main results and implications for practice. PMID:25416377

  8. Improving Emergency Preparedness System Readiness through Simulation and Interprofessional Education

    PubMed Central

    Rambeck, Joan H.; Snyder, Annamay

    2014-01-01

    We applied emerging evidence in simulation science to create a curriculum in emergency response for health science students and professionals. Our research project was designed to (1) test the effectiveness of specific immersive simulations, (2) create reliable assessment tools for emergency response and team communication skills, and (3) assess participants' retention and transfer of skills over time. We collected both quantitative and qualitative data about individual and team knowledge, skills, and attitudes. Content experts designed and pilot-tested scaled quantitative tools. Qualitative evaluations administered immediately after simulations and longitudinal surveys administered 6–12 months later measured student participants' individual perceptions of their confidence, readiness for emergency response, and transfer of skills to their day-to-day experience. Results from 312 participants enrolled in nine workshops during a 24-month period indicated that the 10-hour curriculum is efficient (compared with larger-scale or longer training programs) and effective in improving skills. The curriculum may be useful for public health practitioners interested in addressing public health emergency preparedness competencies and Institute of Medicine research priority areas. PMID:25355984

  9. Improving emergency preparedness system readiness through simulation and interprofessional education.

    PubMed

    Miller, Jane Lindsay; Rambeck, Joan H; Snyder, Annamay

    2014-01-01

    We applied emerging evidence in simulation science to create a curriculum in emergency response for health science students and professionals. Our research project was designed to (1) test the effectiveness of specific immersive simulations, (2) create reliable assessment tools for emergency response and team communication skills, and (3) assess participants' retention and transfer of skills over time. We collected both quantitative and qualitative data about individual and team knowledge, skills, and attitudes. Content experts designed and pilot-tested scaled quantitative tools. Qualitative evaluations administered immediately after simulations and longitudinal surveys administered 6-12 months later measured student participants' individual perceptions of their confidence, readiness for emergency response, and transfer of skills to their day-to-day experience. Results from 312 participants enrolled in nine workshops during a 24-month period indicated that the 10-hour curriculum is efficient (compared with larger-scale or longer training programs) and effective in improving skills. The curriculum may be useful for public health practitioners interested in addressing public health emergency preparedness competencies and Institute of Medicine research priority areas. PMID:25355984

  10. Bio-threat preparedness: Need for a paradigm shift

    PubMed Central

    Jindal, A.K.; Roy, Kaushik

    2014-01-01

    India of late has been vulnerable to Chemical, Biological, Radiological and Nuclear (CBRN) threat, on account of its unique geographic position. Biological threat is an imminent threat in the hands of a terrorist. The public health system of our country is overburdened due to its present role and bio-attack response is not a priority area. This paper suggests that as the prime focus is on the CR and N threats in the integrated CBRN preparedness strategy and that specialized and technical forces are needed to deal with a bio-threat; hence there is a need for a paradigm shift in policy. The emerging field of bio-threat needs to be delinked from the joint family of ‘CBRN’, with consequent structural and functional changes. A separate specialized cadre needs to be formed for dealing with bio-threat, created from the pool of doctors and non-medical scientists from the AFMS and the DRDO. Structural changes are needed in the organization, to bring in the resources of NCDC, New Delhi for enhanced disease surveillance capacity and creation of a bio-threat mitigation node in the AFMC, Pune. PMID:24843207

  11. U.S. preparedness for severe storms questioned

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    Doug Hill, chief meteorologist for WJLA-TV in Washington, D.C., recalled the broadcast news coverage of two supercell thunderstorms that swept through the region on September 24, producing three tornadoes and causing two fatalities. Hill said that only one local radio station which airs his forecasts activated the federal emergency alert system to immediately notify the public about the tornadoes, and added that there should be some changes in requirements. “Somehow, broadcast stations have to get the idea that these warnings and requests to activate [the alerts] are not done [just] for fun,” he said.Hill was among several experts appearing at an October 11 congressional hearing, “Weatherproofing the U.S.: Are We Prepared for Severe Storms?” The hearing, which was held by the U.S. House of Representatives' Science Committee, included testimony about the nation's emergency preparedness in dealing with several types of severe weather: tornadoes, hurricanes, and wind storms.

  12. Emergency preparedness for newborn screening and genetic services.

    PubMed

    Pass, Kenneth A; Thoene, Jess; Watson, Michael S

    2009-06-01

    Patients identified in newborn screening programs can be among the most vulnerable during a disaster due to their need to have prompt diagnosis and medical management. Recent disasters have challenged the ability of newborn screening programs to maintain the needed continuity during emergency situations. This has significant implications for the newborn screening laboratories, the diagnostic confirmation providers, and the patients who either require diagnosis or maintenance of their therapeutic interventions. In 2007, the National Coordinating Center (NCC) for the Regional Genetics and Newborn Screening Collaboratives (RCs) sponsored a meeting involving representatives of the Regional Genetics and Newborn Screening Collaborative Groups, state newborn screening programs, providers of diagnosis and confirmation services, manufacturers of equipment, medical foods, and other treatments used in patients identified in newborn screening programs, and individuals from agencies involved in disaster response including the National Disaster Medical Service, the Centers for Disease Control and Prevention, the Emergency Management Assistance Compact, the Federal Emergency Management Agency, and others. In addition to developing contingency plans for newborn screening, we have considered other uses of genetics as it is used in DNA-based kinship identification of mass casualties. The meeting resulted in the description of a wide range of issues facing newborn screening programs, provider groups, and patients for which emergency preparedness development is needed in order that appropriate response is enabled. PMID:19444127

  13. Preparedness and Mitigation Systems for Asian Tsunami-Type Hazards

    NASA Astrophysics Data System (ADS)

    Aswathanarayana, U.

    2005-03-01

    The devastating impact of the 26 December 2004 Indian Ocean tsunami (also known as the Asian tsunami) on coastal communities has been widely reported in the media. The tsunami has so traumatized the public that governments are under pressure to spend vast amounts of money for warning and protective measures against the tsunamis. It should not, however, be forgotten that tsunamis are comparatively rare events, and consequently the expenditure on preparedness should be commensurate with the probability of risk. It is safe to state that the probability of an equally powerful tsunami being triggered at around the same location in the next few decades is low (http://www.msnbc.msn.com/id/6759529/site/newsweek/), for two reasons: (1) The repeat time for Sumatran-type subduction zone earthquakes is typically 200-300 years; and (2) the tsunami of 26 December was rendered so powerful because of the sudden release of the stress energy that accumulated over a long period of time in the area. This does not, however, preclude less powerful tsunamis from being set off in the future at this or other locations in the Sumatran belt.

  14. Using Computer Games to Communicate Prevention and Preparedness Concepts

    NASA Astrophysics Data System (ADS)

    Kerlow, I.

    2012-12-01

    Earth Girl: The Natural Disaster Fighter is a digital game about a girl who can save her family and friends from natural hazards. The scenario and game play are inspired by the challenges faced by communities living in the Asian regions prone to earthquakes, tsunamis, flooding and volcano hazards. This paper focuses on the interdisciplinary issues and development, the user testing and refinement process and a brief demonstration of the final product. The Earth Girl game is meant to help players, particularly pre-teens worldwide, to gain a better understanding of natural hazards through imaginative and fun game play. The game offers three levels of side-scrolling action, plus factual information in the form of quizzes to enhance the players' knowledge. The correct answers provide players with extra health and/or super-powers. The game was developed in English, Indonesian, Japanese and Chinese. It runs on any Flash-enabled browser and has been successfully user-tested in Southeast Asia with positive results and feedback.Earth Girl, a game of preparedness and survival

  15. Ecological model of disaster management.

    PubMed

    Beaton, Randal; Bridges, Elizabeth; Salazar, Mary K; Oberle, Mark W; Stergachis, Andy; Thompson, Jack; Butterfield, Patricia

    2008-11-01

    The ecological model of disaster management provides a framework to guide occupational health nurses who are developing disaster management programs.This ecological model assumes that disaster planning, preparedness, response, and recovery occur at various levels of the organization. These nested, increasingly complex organizational levels include individual and family, workplace, community, state, tribal, federal, and global levels. The ecological model hypothesizes that these levels interact and these dynamic interactions determine disaster planning, preparedness, response, and recovery outcomes. In addition to the features of the hazard or disaster, it is also assumed that parallel disaster planning, preparedness, and response elements, logistical challenges, and flexibility, sustainability, and rehabilitation elements occur at each level of the ecological model. Finally, the model assumes that evaluation of response and recovery efforts should inform future planning and preparedness efforts. PMID:19051571

  16. Acquired Surface Dyslexia: The Evidence from Hebrew.

    ERIC Educational Resources Information Center

    Birnboim, Smadar

    1995-01-01

    Investigates the symptoms of acquired surface dyslexia in Hebrew. Four acquired surface dyslexic adults were compared with eight normal second graders in terms of reading strategy. Homophones and homographs were a major source of difficulty for native Hebrew surface dyslexic readers; the normal second graders used a non-lexical strategy. (45…

  17. Acquiring and Managing Electronic Journals. ERIC Digest.

    ERIC Educational Resources Information Center

    Curtis, Donnelyn; Yue, Paoshan

    Electronic journals are both a blessing and a curse for libraries. To be meaningful in the current information environment--to meet users' ever-increasing demands--libraries must acquire as many appropriate full text resources as possible, as quickly as possible, and make them easy to use. This Digest provides tips for acquiring and providing…

  18. Acquired Zinc Deficiency in an Adult Female

    PubMed Central

    Saritha, Mohanan; Gupta, Divya; Chandrashekar, Laxmisha; Thappa, Devinder M; Rajesh, Nachiappa G

    2012-01-01

    Acrodermatitis enteropathica is an autosomal recessive inherited disorder of zinc absorption. Acquired cases are reported occasionally in patients with eating disorders or Crohn's disease. We report a 24-year-old housewife with acquired isolated severe zinc deficiency with no other comorbidities to highlight the rare occurrence of isolated nutritional zinc deficiency in an otherwise normal patient. PMID:23248371

  19. Acquired prosopagnosia: structural basis and processing impairments.

    PubMed

    Davies-Thompson, Jodie; Pancaroglu, Raika; Barton, Jason

    2014-01-01

    Cognitive models propose a hierarchy of parallel processing stages in face perception, and functional neuroimaging shows a network of regions involved in face processing. Reflecting this, acquired prosopagnosia is not a single entity but a family of disorders with different anatomic lesions and different functional deficits. One classic distinction is between an apperceptive variant, in which there is impaired perception of facial structure, and an associative/amnestic variant, in which perception is relatively intact, with subsequent problems matching perception to facial memories, because of either disconnection or loss of those memories. These disorders also have to be distinguished from people-specific amnesia, a multimodal impairment, and prosop-anomia, in which familiarity with faces is preserved but access to names is disrupted. These different disorders can be conceived as specific deficits at different processing stages in cognitive models, and suggests that these functional stages may have distinct neuroanatomic substrates. It remains to be seen whether a similar anatomic and functional variability is present in developmental prosopagnosia. PMID:24389150

  20. Acquired hemophilia masked by warfarin therapy.

    PubMed

    Kantor, R; Mayan, H; Puritz, L; Varon, D; Farfel, Z

    2000-03-01

    People without hemophilia but with autoantibodies specifically directed against the procoagulant activity of factor VIII are known to have acquired hemophilia. The bleeding diathesis in these patients is often severe and life-threatening. The definite laboratory diagnosis of this disorder includes demonstration of low factor VIII levels in plasma with a high titer of factor VIII inhibitors, but the initial suspicion for its presence should rise in view of a prolonged partial thromboblastin time (PTT) and a normal prothrombin time associated with an acquired bleeding disorder. Oral anticoagulant treatment is known to prolong PTT as well, and the merger of these 2 situations may cause delayed diagnosis of acquired hemophilia with devastating consequences. We describe here the first reported case of acquired hemophilia diagnosed in a patient treated with warfarin. In such patients prolonged PTT may be ascribed to warfarin therapy rather than to acquired hemophilia, thus causing a dangerous delay in diagnosis. PMID:10746834