Science.gov

Sample records for act caa requires

  1. A historical overview of the development of manganese (Mn) pharmacokinetic data under Section 211(b) of the Clean Air Act (CAA)

    EPA Science Inventory

    Abstract for Manganese 2016A historical overview of the development of manganese (Mn) pharmacokinetic data under Section 211(b) of the Clean Air Act (CAA)William K BoyesBackground. In the 1990’s, the use of methylcyclopentadienyl manganese tricarbonyl (MMT) as an octane-enh...

  2. State Implementation Plans; General Preamble & Lead (Pb) Addendum for the Implementation of Title I of the Clean Air Act (CAA) Amendments of 1990 (57 FR 13498 & 58 FR 67748)

    EPA Pesticide Factsheets

    This page contains a copy of the 1993 & 1993 Federal Register publications of the State Implementation Plans (SIPs); General Preamble & Lead (Pb) Addendum for the Implementation of Title I of the Clean Air Act (CAA) Amendments of 1990.

  3. 76 FR 29688 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... State meets the requirements of section 110(a)(1) and (2) of the Clean Air Act (CAA) for the National... March 27, 2008 (73 FR 16205), and one dated December 21, 2009. EPA does not propose to act on the State...: (i) The words or initials Act or CAA mean or refer to the Clean Air Act, unless the context...

  4. 76 FR 28707 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... SIP meets the requirements of Sections 110(a)(1) and (2) of the Clean Air Act (CAA) for the National..., 2008 which was determined to be complete on March 27, 2008 (73 FR 16205). EPA does not propose to act...: (i) The words or initials Act or CAA mean or refer to the Clean Air Act, unless the context...

  5. 29 CFR 457.10 - CSRA; FSA; CAA; LMRDA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT GENERAL Meaning of Terms as Used in This Chapter § 457.10 CSRA; FSA; CAA; LMRDA. CSRA means the Civil... Accountability Act of 1995; LMRDA means the Labor-Management Reporting and Disclosure Act of 1959, as amended....

  6. 77 FR 6044 - Approval and Promulgation of Implementation Plans; Oregon: Infrastructure Requirements for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... 110(a)(1) and (2) of the Clean Air Act (CAA) for the National Ambient Air Quality Standards (NAAQS... Act (CAA) for the National Ambient Air Quality Standards (NAAQS) promulgated for ozone on July 18... EPA intends to act on at a later time. This action also does not address the requirements of...

  7. CAA for Jet Noise Physics

    NASA Technical Reports Server (NTRS)

    Mankbadi, Reda

    2001-01-01

    Dr. Mankbadi summarized recent CAA results. Examples of the effect of various boundary condition schemes on the computed acoustic field, for a point source in a uniform flow, were shown. Solutions showing the impact of inflow excitations on the result were also shown. Results from a large eddy simulation, using a fourth-order MacCormack scheme with a Smagorinsky sub-grid turbulence model, were shown for a Mach 2.1 unheated jet. The results showed that the results were free from spurious modes. Results were shown for a Mach 1.4 jet using LES in the near field and the Kirchhoff method for the far field. Predicted flow field characteristics were shown to be in good agreement with data and predicted far field directivities were shown to be in qualitative agree with experimental measurements.

  8. CERCLA compliance with other laws manual: Summary and Part 2. CAA, TSCA, and other statutes. Fact sheet (Final)

    SciTech Connect

    Not Available

    1990-04-01

    The fact sheet provides a guide to Chapters 2 and 3 of Part II of the CERCLA Compliance With Other Laws Manual. The sixth in a series, this fact sheet focuses on CERCLA compliance with the Clean Air Act (CAA), the Toxic Substances Control Act (TSCA), and the Federal Insecticide, Fungicide, and Rodenticide Act. In addition, it discusses other statutes that set standards for radioactive wastes, mining wastes, and other resource protection statutes that are potential Applicable or Relevant and Appropriate Requirements (ARARs) for CERCLA actions.

  9. 25 CFR 273.54 - Privacy Act requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Privacy Act requirements. 273.54 Section 273.54 Indians... Privacy Act requirements. (a) When a contractor operates a system of records to accomplish a Bureau function, the contractor shall comply with subpart D of 43 CFR part 2 which implements the Privacy Act (5...

  10. 25 CFR 273.54 - Privacy Act requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Privacy Act requirements. 273.54 Section 273.54 Indians... Privacy Act requirements. (a) When a contractor operates a system of records to accomplish a Bureau function, the contractor shall comply with subpart D of 43 CFR part 2 which implements the Privacy Act (5...

  11. 25 CFR 273.54 - Privacy Act requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Privacy Act requirements. 273.54 Section 273.54 Indians... Privacy Act requirements. (a) When a contractor operates a system of records to accomplish a Bureau function, the contractor shall comply with subpart D of 43 CFR part 2 which implements the Privacy Act (5...

  12. 25 CFR 273.54 - Privacy Act requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Privacy Act requirements. 273.54 Section 273.54 Indians... Privacy Act requirements. (a) When a contractor operates a system of records to accomplish a Bureau function, the contractor shall comply with subpart D of 43 CFR part 2 which implements the Privacy Act (5...

  13. 25 CFR 273.54 - Privacy Act requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Privacy Act requirements. 273.54 Section 273.54 Indians... Privacy Act requirements. (a) When a contractor operates a system of records to accomplish a Bureau function, the contractor shall comply with subpart D of 43 CFR part 2 which implements the Privacy Act (5...

  14. Plainer Legal Language: Definitions and Requirements in Acts.

    ERIC Educational Resources Information Center

    Jordan, Michael P.

    1994-01-01

    Explores some of the stylistic complexities of definitions and requirements in a Canadian provincial act. Generates and justifies 15 recommendations for creating a plainer legal language in acts. (SR)

  15. Clean Air Act Requirements and History

    EPA Pesticide Factsheets

    In 1970 congress designed the Clean Air Act to combat a variety of air pollution problems, and to tackle emerging pollution threats such as public health, national welfare, toxic air pollutants, acid rain, protection of the ozone layer, and regional haze.

  16. 75 FR 18043 - Combating Noncompliance With Recovery Act Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ... Memorandum of April 6, 2010--Combating Noncompliance With Recovery Act Reporting Requirements #0; #0; #0... Noncompliance With Recovery Act Reporting Requirements Memorandum for the Heads of Executive Departments and Agencies My Administration is committed to transparency in tracking recovery dollars and to elimination...

  17. Streamlining CAA compliance plans yields added benefits

    SciTech Connect

    Miller, D.A. )

    1993-02-01

    A common approach to compliance with air emissions standards at some facilities consists of correcting deficiencies noted by regulators during their annual or semi-annual visits without developing long-term compliance plans. Many times, plant officials do not know which regulations apply to their sources. Industry no longer can afford to depend on such hit-or-miss compliance strategies. Under the CAA Amendments, EPA is empowerd to issue field citations of $5,000 per day for each violation, and monetary penalties can reach millions of dollars and be accompanied by prison sentences up to 15 years. Developing a plant-wide emissions compliance plan is one of the best ways to minimize future compliance liabilities. Data collected for such plans typically are stored in a computerized database, which also can be used in other compliance activities.

  18. 30 CFR 252.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR parts 251 and 551 (Geological and Geophysical Explorations of the Outer Continental...

  19. 30 CFR 252.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR parts 251 and 551 (Geological and Geophysical Explorations of the Outer Continental...

  20. 30 CFR 552.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR part 551 (Geological and Geophysical Explorations of the Outer Continental Shelf)....

  1. 30 CFR 552.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR part 551 (Geological and Geophysical Explorations of the Outer Continental Shelf)....

  2. 30 CFR 252.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR parts 251 and 551 (Geological and Geophysical Explorations of the Outer Continental...

  3. 30 CFR 552.6 - Freedom of Information Act requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... contained in 43 CFR part 2 (Records and Testimony), the requirements of the Act, and the regulations...) and 30 CFR part 551 (Geological and Geophysical Explorations of the Outer Continental Shelf)....

  4. Infrastructure Task Force National Environmental Policy Act Requirements - February 2011

    EPA Pesticide Factsheets

    This document summarizes in a matrix format the federal regulations requirements and guidance for complying with the National Environmental Policy Act for the Infrastructure Task Force federal partner agencies.

  5. Second Computational Aeroacoustics (CAA) Workshop on Benchmark Problems

    NASA Technical Reports Server (NTRS)

    Tam, C. K. W. (Editor); Hardin, J. C. (Editor)

    1997-01-01

    The proceedings of the Second Computational Aeroacoustics (CAA) Workshop on Benchmark Problems held at Florida State University are the subject of this report. For this workshop, problems arising in typical industrial applications of CAA were chosen. Comparisons between numerical solutions and exact solutions are presented where possible.

  6. 40 CFR 51.126 - Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline vapor recovery requirements. 51.126 Section 51... Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline vapor...

  7. Pollution prevention requirements in United States environmental laws

    SciTech Connect

    Thurber, J.; Sherman, P.

    1995-09-01

    This section discusses federal legal authority to require pollution prevention. It presents an overview of the authority to implement pollution prevention that exists in the following major environmental statutes: the Pollution Prevent Act (PPA); the Resource Conservation and Recovery Act (RCRA); the Clean Air Act (CAA); the Clean Water Act (CWA); the Toxic Substances Control Act (TSCA); the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).

  8. Clean Air Act requirements for trace-metals information

    SciTech Connect

    Pahl, D.; Hunt, W.; Evans, G.

    1992-01-01

    The Clean Air Act Amendments of 1990 have expanded the requirements for trace metal and air toxics information in urban areas and added new requirements for this information in rural areas and ecosystems. Specific provisions germane to trace metals and other air toxics compounds are found in Title III, Section 112 and in Title IX, Section 901. In response to these provisions, the United States Environmental Protection Agency (EPA) plans to conduct research in atmospheric monitoring networks in urban areas, in the Great Lakes watershed, and in regional components of a national Clean Air Act status and trends network.

  9. Compliance with the Clean Air Act Title VI Stratospheric Ozone Protection Program requirements at U.S. DOE Oak Ridge Reservation Facilities

    SciTech Connect

    Humphreys, M.P.; Atkins, E.M.

    1999-07-01

    The Title VI Stratospheric Ozone Protection Program of the Clean Air Act (CAA) requires promulgation of regulations to reduce and prevent damage to the earth's protective ozone layer. Regulations pursuant to Title VI of the CAA are promulgated in the Code of Federal Regulations (CFR) at Title 40 CFR, Part 822. The regulations include ambitious production phaseout schedules for ozone depleting substances (ODS) including chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), halons, carbon tetrachloride, and methyl chloroform under 40 CFR 82, Subpart A. The regulations also include requirements for recycling and emissions reduction during the servicing of refrigeration equipment and technician certification requirements under Subpart F; provisions for servicing of motor vehicle air conditioners under Subpart B; a ban on nonessential products containing Class 1 ODS under Subpart C; restrictions on Federal procurement of ODS under Subpart D; labeling of products using ODS under Subpart E; and the Significant New Alternatives Policy Program under Subpart G. This paper will provide details of initiatives undertaken at US Department of Energy (DOE) Oak Ridge Reservation (ORR) Facilities for implementation of requirements under the Title VI Stratospheric Ozone Protection Program. The Stratospheric Ozone Protection Plans include internal DOE requirements for: (1) maintenance of ODS inventories; (2) ODS procurement practices; (3) servicing of refrigeration and air conditioning equipment; (4) required equipment modifications or replacement; (5) technician certification training; (6) labeling of products containing ODS; (7) substitution of chlorinated solvents; and (8) replacement of halon fire protection systems. The plans also require establishment of administrative control systems which assure that compliance is achieved and maintained as the regulations continue to develop and become effective.

  10. Implementation of the Clean Air Act, Title V operating permit program requirements for the U.S. DOE Oak Ridge Reservation facilities

    SciTech Connect

    Humphreys, M.P.

    1998-12-31

    Title V of the Clean Air Act (CAA) establishes a new permit program requiring major sources and sources subject to Title III (Hazardous Air Pollutants) to obtain a state operating permit. Historically, most states have issued operating permits for individual emission units. Under the Title V permit program, a single permit will be issued for all of the emission units at the facility much like the current National Pollutant Discharge Elimination System (NPDES) permit program. The permit will specify all reporting, monitoring, and record-keeping requirements for the facility. Sources required to obtain permits include (a) major sources that emit 100 tons per year or more of any criteria air contaminant, (b) any source subject to the HAP provisions of Title III, (c) any source subject to the acid rain provisions of Title IV, (d) any source subject to New Source Performance Standards, and (e) any source subject to new source review under the nonattainment or Prevention of Significant Deterioration provisions. The State of Tennessee Title V Operating Permit Program was approved by EPA on August 28, 1996. This paper will provide details of initiatives underway at US Department of Energy (DOE) Oak Ridge Reservation (ORR) Facilities for implementation of requirements under the Title V Operating Permit Program. The ORR encompasses three DOE Facilities: the Y-12 Plant, Oak Ridge National Laboratory (ORNL), and the East Tennessee Technology Park (ETTP). The Y-12 Plant manufactures component parts for the national nuclear weapons program; the ORNL is responsible for research and development activities including nuclear engineering, engineering technologies, and the environmental sciences; and the ETTP conducts a variety of research and development activities and is the home of a mixed waste incinerator. Each of the three DOE Facilities is considered a major source under Title V of the CAA.

  11. Benchmark Solutions for Computational Aeroacoustics (CAA) Code Validation

    NASA Technical Reports Server (NTRS)

    Scott, James R.

    2004-01-01

    NASA has conducted a series of Computational Aeroacoustics (CAA) Workshops on Benchmark Problems to develop a set of realistic CAA problems that can be used for code validation. In the Third (1999) and Fourth (2003) Workshops, the single airfoil gust response problem, with real geometry effects, was included as one of the benchmark problems. Respondents were asked to calculate the airfoil RMS pressure and far-field acoustic intensity for different airfoil geometries and a wide range of gust frequencies. This paper presents the validated that have been obtained to the benchmark problem, and in addition, compares them with classical flat plate results. It is seen that airfoil geometry has a strong effect on the airfoil unsteady pressure, and a significant effect on the far-field acoustic intensity. Those parts of the benchmark problem that have not yet been adequately solved are identified and presented as a challenge to the CAA research community.

  12. Required reading. Federal Disabilities Act increases litigation risks for providers.

    PubMed

    O'Hare, P K; Schmidt, W T

    1991-04-01

    The Americans with Disabilities Act of 1990 (ADA) is considered the most sweeping civil rights legislation since the Civil Rights Act of 1964. The two parts of the ADA that apply most directly to healthcare providers are the prohibitions on employment discrimination and the requirements for provision of services to persons with disabilities. The ADA states that a person's disability should not be an adverse factor in employment decisions. Employers must make "reasonable accommodations" to the qualified person's known impairment so that person can perform his or her job more easily. The ADA also prohibits private entities from discriminating against persons with disabilities in the full and equal enjoyment of services (i.e., "public accommodations"). Providers will have an affirmative duty to remove (in existing buildings) architectural elements proven to be barriers to persons with disabilities. Public access requirements apply to new building construction as well. Healthcare providers must also install wheelchair lifts in shuttle bus systems they operate. Healthcare providers, both as employers and providers of public services, now have just a matter of months in which to respond to these new requirements. Planning efforts to ensure compliance should begin immediately.

  13. 78 FR 8273 - Approval of Air Quality Implementation Plans; Navajo Nation; Regional Haze Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ...The Environmental Protection Agency (EPA) is proposing a source-specific federal implementation plan (FIP) requiring the Navajo Generating Station (NGS), located on the Navajo Nation, to reduce emissions of oxides of nitrogen (NOX) under the Best Available Retrofit Technology (BART) provision of the Clean Air Act (CAA or Act) in order to reduce visibility impairment resulting from......

  14. Fourth Computational Aeroacoustics (CAA) Workshop on Benchmark Problems

    NASA Technical Reports Server (NTRS)

    Dahl, Milo D. (Editor)

    2004-01-01

    This publication contains the proceedings of the Fourth Computational Aeroacoustics (CAA) Workshop on Benchmark Problems. In this workshop, as in previous workshops, the problems were devised to gauge the technological advancement of computational techniques to calculate all aspects of sound generation and propagation in air directly from the fundamental governing equations. A variety of benchmark problems have been previously solved ranging from simple geometries with idealized acoustic conditions to test the accuracy and effectiveness of computational algorithms and numerical boundary conditions; to sound radiation from a duct; to gust interaction with a cascade of airfoils; to the sound generated by a separating, turbulent viscous flow. By solving these and similar problems, workshop participants have shown the technical progress from the basic challenges to accurate CAA calculations to the solution of CAA problems of increasing complexity and difficulty. The fourth CAA workshop emphasized the application of CAA methods to the solution of realistic problems. The workshop was held at the Ohio Aerospace Institute in Cleveland, Ohio, on October 20 to 22, 2003. At that time, workshop participants presented their solutions to problems in one or more of five categories. Their solutions are presented in this proceedings along with the comparisons of their solutions to the benchmark solutions or experimental data. The five categories for the benchmark problems were as follows: Category 1:Basic Methods. The numerical computation of sound is affected by, among other issues, the choice of grid used and by the boundary conditions. Category 2:Complex Geometry. The ability to compute the sound in the presence of complex geometric surfaces is important in practical applications of CAA. Category 3:Sound Generation by Interacting With a Gust. The practical application of CAA for computing noise generated by turbomachinery involves the modeling of the noise source mechanism as a

  15. 77 FR 30555 - Notice of Lodging of Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... of Lodging of Consent Decree Under the Clean Air Act Notice is hereby given that on May 16, 2012, a proposed Consent Decree in United States et al. v. Questar Gas Management Co., Civil Action No. 2:08-cv... the CAA, 42 U.S.C. 7661-7661f and 40 CFR part 71. The proposed consent decree would require QEPFS...

  16. 75 FR 49947 - Notice of Lodging of Proposed Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... of Lodging of Proposed Consent Decree Under the Clean Air Act Notice is hereby given that on August 6, 2010, a proposed Consent Decree in United States v. Premix, Inc., Civil Action No. 1:10-cv- 01732-DAP... Section 114 of the CAA, 33 U.S.C. 7414. Under the proposed Consent Decree, Premix is required to...

  17. Nonattainment and Ozone Transport Region (OTR) SIP Requirements

    EPA Pesticide Factsheets

    The Clean Air Act (CAA) requires a group of northeast states, which make up the Ozone Transport Region (OTR), to submit a SIP and install a certain level of controls for the pollutants that form ozone, even if they meet ozone standards.

  18. 76 FR 15308 - Completion of the Requirement To Promulgate Emission Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... AGENCY Completion of the Requirement To Promulgate Emission Standards AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces that EPA has completed the emission...) of the Clean Air Act (CAA) requires that, by November 15, 2000, EPA promulgate emission standards...

  19. Third Computational Aeroacoustics (CAA) Workshop on Benchmark Problems

    NASA Technical Reports Server (NTRS)

    Dahl, Milo D. (Editor)

    2000-01-01

    The proceedings of the Third Computational Aeroacoustics (CAA) Workshop on Benchmark Problems cosponsored by the Ohio Aerospace Institute and the NASA Glenn Research Center are the subject of this report. Fan noise was the chosen theme for this workshop with representative problems encompassing four of the six benchmark problem categories. The other two categories were related to jet noise and cavity noise. For the first time in this series of workshops, the computational results for the cavity noise problem were compared to experimental data. All the other problems had exact solutions, which are included in this report. The Workshop included a panel discussion by representatives of industry. The participants gave their views on the status of applying computational aeroacoustics to solve practical industry related problems and what issues need to be addressed to make CAA a robust design tool.

  20. Hybrid CFD/CAA Modeling for Liftoff Acoustic Predictions

    NASA Technical Reports Server (NTRS)

    Strutzenberg, Louise L.; Liever, Peter A.

    2011-01-01

    This paper presents development efforts at the NASA Marshall Space flight Center to establish a hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) simulation system for launch vehicle liftoff acoustics environment analysis. Acoustic prediction engineering tools based on empirical jet acoustic strength and directivity models or scaled historical measurements are of limited value in efforts to proactively design and optimize launch vehicles and launch facility configurations for liftoff acoustics. CFD based modeling approaches are now able to capture the important details of vehicle specific plume flow environment, identifY the noise generation sources, and allow assessment of the influence of launch pad geometric details and sound mitigation measures such as water injection. However, CFD methodologies are numerically too dissipative to accurately capture the propagation of the acoustic waves in the large CFD models. The hybrid CFD/CAA approach combines the high-fidelity CFD analysis capable of identifYing the acoustic sources with a fast and efficient Boundary Element Method (BEM) that accurately propagates the acoustic field from the source locations. The BEM approach was chosen for its ability to properly account for reflections and scattering of acoustic waves from launch pad structures. The paper will present an overview of the technology components of the CFD/CAA framework and discuss plans for demonstration and validation against test data.

  1. 78 FR 54252 - Information Collection; American Recovery and Reinvestment Act-Reporting Requirements-One Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ...; American Recovery and Reinvestment Act-- Reporting Requirements--One Time Reporting Requirements for Prime... concerning the American Recovery and Reinvestment Act--Reporting Requirements--One Time Reporting... Requirements-- One Time Reporting Requirements for Prime Contractors, by any of the following...

  2. NASA's Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia

    2003-01-01

    Marshall Space Flight Center (MSFC) was selected as the Principal Center for review of Clean Air Act (CAA) regulations. The CAA Principal Center is tasked to: 1) Provide centralized support to NASA/HDQ Code JE for the management and leadership of NASA's CAA regulation review process; 2) Identify potential impact from proposed CAA regulations to NASA program hardware and supporting facilities. The Shuttle Environmental Assurance Initiative, one of the responsibilities of the NASA CAA Working Group (WG), is described in part of this viewgraph presentation.

  3. 29 CFR 1977.3 - General requirements of section 11(c) of the Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false General requirements of section 11(c) of the Act. 1977.3... WILLIAMS-STEIGER OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 General § 1977.3 General requirements of section 11(c) of the Act. Section 11(c) provides in general that no person shall discharge or in...

  4. 17 CFR 23.440 - Requirements for swap dealers acting as advisors to Special Entities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Requirements for swap dealers acting as advisors to Special Entities. 23.440 Section 23.440 Commodity and Securities Exchanges....440 Requirements for swap dealers acting as advisors to Special Entities. (a) Acts as an advisor to...

  5. 17 CFR 23.440 - Requirements for swap dealers acting as advisors to Special Entities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Requirements for swap dealers acting as advisors to Special Entities. 23.440 Section 23.440 Commodity and Securities Exchanges....440 Requirements for swap dealers acting as advisors to Special Entities. (a) Acts as an advisor to...

  6. Cluster Ion Spectrometry (CIS) Data Archiving in the CAA

    NASA Astrophysics Data System (ADS)

    Dandouras, I. S.; Barthe, A.; Penou, E.; Brunato, S.; Reme, H.; Kistler, L. M.; Blagau, A.; Facsko, G.; Kronberg, E.; Laakso, H. E.

    2009-12-01

    The Cluster Active Archive (CAA) aims at preserving the four Cluster spacecraft data, so that they are usable in the long-term by the scientific community as well as by the instrument team PIs and Co-Is. This implies that the data are filed together with the descriptive and documentary elements making it possible to select and interpret them. The CIS (Cluster Ion Spectrometry) experiment is a comprehensive ionic plasma spectrometry package onboard the four Cluster spacecraft, capable of obtaining full three-dimensional ion distributions (about 0 to 40 keV/e) with a time resolution of one spacecraft spin (4 sec) and with mass-per-charge composition determination. The CIS package consists of two different instruments, a Hot Ion Analyser (HIA) and a time-of-flight ion Composition Distribution Function (CODIF) analyser. For the archival of the CIS data a multi-level approach has been adopted. The CAA archival includes processed raw data (Level 1 data), moments of the ion distribution functions (Level 2 data), and calibrated high-resolution data in a variety of physical units (Level 3 data). The latter are 3-D ion distribution functions and 2-D pitch-angle distributions. In addition, a software package has been developed to allow the CAA user to interactively calculate partial or total moments of the ion distributions. Instrument cross-calibration has been an important activity in preparing the data for archival. The CIS data archive includes also experiment documentation, graphical products for browsing through the data, and data caveats. In addition, data quality indexes are under preparation, to help the user. Given the complexity of an ion spectrometer, and the variety of its operational modes, each one being optimised for a different magnetospheric region or measurement objective, consultation of the data caveats by the end user will always be a necessary step in the data analysis.

  7. 75 FR 75692 - Manufactured Home Construction and Safety Standards Act Reporting Requirements; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-06

    ... URBAN DEVELOPMENT Manufactured Home Construction and Safety Standards Act Reporting Requirements; Notice... Safety Standards Reporting Requirements. OMB Control Number, if applicable: 2502-0253. Description of the... Housing, HUD. ACTION: Notice. SUMMARY: The proposed information collection requirement described...

  8. NASA Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia; Munafo, Paul M. (Technical Monitor)

    2002-01-01

    The Clean Air Act (CAA) regulations have greatly impacted materials and processes utilized in the manufacture of aerospace hardware. Code JE/ NASA's Environmental Management Division at NASA Headquarters recognized the need for a formal, Agency-wide review process of CAA regulations. Marshall Space Flight Center (MSFC) was selected as the 'Principal Center for Review of Clean Air Act Regulations'. This presentation describes the centralized support provided by MSFC for the management and leadership of NASA's CAA regulation review process.

  9. CAA amendments` Title III could mean `future shock` to U.S. industry competitiveness

    SciTech Connect

    Rocco, V.A.

    1995-06-01

    While the regulated community awaits congressional action that could alter the government`s role in environmental protection and enforcement, the stipulations of existing regulations continue to unfold. Attention is focused on upcoming permitting deadlines imposed by the Clean Air Act Amendments of 1990, due by November for most facilities, and on products and strategies for air pollution control. Unless Congress adopts the unlikely strategy of rolling back all environmental regulations, the obligations on industry imposed by the CAA Amendments will continue to set forth a formidable compliance task. The Amendments ``created a complex maze of new and dramatically altered regulatory programs that will influence how US industry must operate well into the next century.`` This article provides an overview and guidelines for complying with the new rules.

  10. 20 CFR 667.300 - What are the reporting requirements for Workforce Investment Act programs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false What are the reporting requirements for Workforce Investment Act programs? 667.300 Section 667.300 Employees' Benefits EMPLOYMENT AND TRAINING... INVESTMENT ACT Reporting Requirements § 667.300 What are the reporting requirements for Workforce...

  11. 47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...

  12. 47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...

  13. 47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...

  14. 47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...

  15. 47 CFR 80.163 - Operator requirements of the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Operator requirements of the Bridge-to-Bridge... Requirements § 80.163 Operator requirements of the Bridge-to-Bridge Act. Each ship subject to the Bridge-to-Bridge Act must have on board a radio operator who holds a restricted radiotelephone operator permit...

  16. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Bridge-to-Bridge Act. 80... RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch...

  17. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch requirements of the Communications Act... (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.305 Watch requirements of the Communications Act and the...

  18. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Bridge-to-Bridge Act. 80... RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch...

  19. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Bridge-to-Bridge Act. 80... RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch...

  20. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch requirements of the Communications Act... (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.305 Watch requirements of the Communications Act and the...

  1. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Bridge-to-Bridge Act. 80... RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch...

  2. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch requirements of the Communications Act... (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.305 Watch requirements of the Communications Act and the...

  3. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Bridge-to-Bridge Act. 80... RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch...

  4. Antioxidant activity of puha (Sonchus oleraceus L.) as assessed by the cellular antioxidant activity (CAA) assay.

    PubMed

    McDowell, Arlene; Thompson, Scott; Stark, Mirjam; Ou, Zong-Quan; Gould, Kevin S

    2011-12-01

    There is considerable interest in antioxidant dietary components that can be protective against degenerative diseases in humans. Puha (Sonchus oleraceus L.) is a rich source of polyphenols, and exhibits strong antioxidant activity as measured by the 2,2-diphenylpicrylhydrazyl (DPPH) assay. However, the potential of puha to protect against degenerative diseases requires that low molecular weight antioxidants (LMWA) are absorbed by, and active in, human cells. The cellular antioxidant activity (CAA) assay was used to investigate the antioxidant activity of puha leaf extracts. Preparation methods of freezing and freeze-drying reduced the total polyphenolic content compared with fresh puha, but did not affect the LMWA potential as determined by the DPPH assay. The IC(50) values were 0.012 ± 0.003 mg/mL and 0.010 ± 0.005 mg/mL for freeze-dried and fresh puha leaves, respectively. Using the CAA assay, it was shown that LMWAs from foliar extracts of puha were effectively absorbed into HepG2 cells, and exerted antioxidant activity at levels comparable to those of extracts from blueberry fruits, the much-touted antioxidant superfood. Methylene blue staining of HepG2 cells indicated that puha extracts were not cytotoxic at concentrations below 100 mg DW/mL. The data indicate the potential of puha as a nutraceutical supplement for human health.

  5. 75 FR 22805 - Submission for OMB Review; American Recovery and Reinvestment Act-One-Time Reporting Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ...; American Recovery and Reinvestment Act--One-Time Reporting Requirements for Prime Contractors AGENCIES... Recovery and Reinvestment Act--One-time Reporting Requirements for Prime Contractors published in...

  6. A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes

    PubMed Central

    Hildebrandt, Emily R; Cheng, Michael; Zhao, Peng; Kim, June H; Wells, Lance; Schmidt, Walter K

    2016-01-01

    The modifications occurring to CaaX proteins have largely been established using few reporter molecules (e.g. Ras, yeast a-factor mating pheromone). These proteins undergo three coordinated COOH-terminal events: isoprenylation of the cysteine, proteolytic removal of aaX, and COOH-terminal methylation. Here, we investigated the coupling of these modifications in the context of the yeast Ydj1p chaperone. We provide genetic, biochemical, and biophysical evidence that the Ydj1p CaaX motif is isoprenylated but not cleaved and carboxylmethylated. Moreover, we demonstrate that Ydj1p-dependent thermotolerance and Ydj1p localization are perturbed when alternative CaaX motifs are transplanted onto Ydj1p. The abnormal phenotypes revert to normal when post-isoprenylation events are genetically interrupted. Our findings indicate that proper Ydj1p function requires an isoprenylatable CaaX motif that is resistant to post-isoprenylation events. These results expand on the complexity of protein isoprenylation and highlight the impact of post-isoprenylation events in regulating the function of Ydj1p and perhaps other CaaX proteins. DOI: http://dx.doi.org/10.7554/eLife.15899.001 PMID:27525482

  7. 75 FR 232 - Finding of Failure To Submit Certain State Implementation Plans Required for the 1-Hour Ozone NAAQS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ... Ozone NAAQS AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The EPA is... Implementation Plans (SIPs) for three ozone nonattainment areas to satisfy certain requirements of the Clean Air Act (CAA) for the 1-hour ozone National Ambient Air Quality Standards (NAAQS). To accompany...

  8. CAA for Jet Noise Physics: Issues and Recent Progress

    NASA Technical Reports Server (NTRS)

    Mankbadi, Reda

    2001-01-01

    Dr. Mankbadi summarized recent CAA results. Examples of the effect of various boundary condition schemes on the computed acoustic field, for a point source in a uniform flow, were shown. Solutions showing the impact of inflow excitations on the result were also shown. Results from a large eddy simulation, using a fourth-order MacCormack scheme with a Smagorinsky sub-grid turbulence model, were shown for a Mach 2.1 unheated jet. The results showed that the results were free from spurious modes. Results were shown for a Mach 1.4 jet using LES in the near field and the Kirchhoff method for the far field. Predicted flow field characteristics were shown to be in good agreement with data and predicted far field directivities were shown to be in qualitative agree with experimental measurements.

  9. Two-Year College Compliance with the Notice Requirements of the Campus Security Act.

    ERIC Educational Resources Information Center

    Callaway, Robert L.; Gehring, Donald D.; Douthett, Tracy J.

    2000-01-01

    Investigates if two-year colleges are complying with the notice requirement of the Campus Security Act by providing everyone requesting admission information a summary of the contents of their security report. Finds that only slightly more than 6% of the two-year colleges surveyed met the notice requirement of the Campus Security Act. (VWC)

  10. 77 FR 13617 - Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-07

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements AGENCY: U.S. Customs and Border Protection (CBP), Department of... concerning the Customs Modernization Act Recordkeeping Requirements. This request for comment is being...

  11. 5 CFR 1830.2 - Requirements for making Privacy Act requests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Requirements for making Privacy Act requests. 1830.2 Section 1830.2 Administrative Personnel OFFICE OF SPECIAL COUNSEL PRIVACY § 1830.2 Requirements for making Privacy Act requests. (a) How made and addressed. A request for OSC records under...

  12. 5 CFR 1830.2 - Requirements for making Privacy Act requests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Requirements for making Privacy Act requests. 1830.2 Section 1830.2 Administrative Personnel OFFICE OF SPECIAL COUNSEL PRIVACY § 1830.2 Requirements for making Privacy Act requests. (a) How made and addressed. A request for OSC records under...

  13. 5 CFR 1830.2 - Requirements for making Privacy Act requests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Requirements for making Privacy Act requests. 1830.2 Section 1830.2 Administrative Personnel OFFICE OF SPECIAL COUNSEL PRIVACY § 1830.2 Requirements for making Privacy Act requests. (a) How made and addressed. A request for OSC records under...

  14. 15 CFR 930.37 - Consistency determinations and National Environmental Policy Act (NEPA) requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Consistency determinations and National Environmental Policy Act (NEPA) requirements. 930.37 Section 930.37 Commerce and Foreign Trade... National Environmental Policy Act (NEPA) requirements. A Federal agency may use its NEPA documents as...

  15. 28 CFR 55.22 - Requirements of section 5 of the Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Requirements of section 5 of the Act. 55.22 Section 55.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) IMPLEMENTATION OF THE PROVISIONS OF THE VOTING RIGHTS ACT REGARDING LANGUAGE MINORITY GROUPS Preclearance § 55.22 Requirements...

  16. 28 CFR 55.22 - Requirements of section 5 of the Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Requirements of section 5 of the Act. 55.22 Section 55.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) IMPLEMENTATION OF THE PROVISIONS OF THE VOTING RIGHTS ACT REGARDING LANGUAGE MINORITY GROUPS Preclearance § 55.22 Requirements...

  17. The enforcement provisions of the Clean Air Act - not the same old Section 113

    SciTech Connect

    Benthul, H.R.

    1996-08-01

    The Clean Air Act ({open_quotes}CAA{close_quotes}) of 1990 was in many respects a major overhaul of the previous versions of the Clean Air Act although it retained most of the preexisting major programs such as the basic National Ambient Air Quality Standards ({open_quotes}NAAQS{close_quotes}) scheme, PSD, new source performance standards, regulation of toxic air pollutants, and the like. The 1990 Act strengthened the enforcement provisions of the Act by enhancing the enforcement powers of the Environmental Protection Agency ({open_quotes}EPA{close_quotes}) of {section}113. For example, the criminal enforcement provisions of {section}113 are expanded both in the range of punishment and in the kinds of activities which are subject to criminal enforcement. Moreover, the Act now contains a number of additional enforcement provisions in addition to those found in {section}113. The purpose of this paper is to discuss both the {section}113 provision and as well, identify those enforcement provisions found outside {section}113. The latter provisions will be taken up first and addressed by Titles of the Act. The discussion of specific sections and subsections of the CAA are necessarily brief and in the nature of highlighting of particular features; like the rest of the CAA, careful reading and analysis is a requirement for full understanding.

  18. Title III List of Lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and Section 112(r) of the Clean Air Act, as amended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990

    SciTech Connect

    1996-12-01

    This consolidated chemical list includes chemicals subject to reporting requirements under Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), also known as the Emergency Planning and Community Right-to-Know Act (EPCRA) and chemicals listed under Section 112(r) of Title III of the Clean Air Act (CAA) Amendments of 1990. This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 314 or SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. It also will also help firms determine whether they will be subject to accident prevention regulations under CAA section 112(r).

  19. 82 FR 4594 - Accidental Release Prevention Requirements: Risk Management Programs Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2017-01-13

    ... to improve chemical process safety, assist local emergency authorities in planning for and responding... environment from chemical hazards through advancement of process safety management based on lessons learned. 2... CFR 1910.119 Process Safety Management (PSM) standard were authorized in the CAA Amendments of...

  20. 48 CFR 352.237-72 - Crime Control Act-requirement for background checks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Crime Control Act... and Clauses 352.237-72 Crime Control Act—requirement for background checks. As prescribed in 337.103-70(c), the Contracting Officer shall insert the following clause: Crime Control Act of...

  1. 48 CFR 352.237-72 - Crime Control Act-requirement for background checks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Crime Control Act... and Clauses 352.237-72 Crime Control Act—requirement for background checks. As prescribed in 337.103-70(c), the Contracting Officer shall insert the following clause: Crime Control Act of...

  2. 48 CFR 352.237-72 - Crime Control Act-requirement for background checks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Crime Control Act... and Clauses 352.237-72 Crime Control Act—requirement for background checks. As prescribed in 337.103-70(c), the Contracting Officer shall insert the following clause: Crime Control Act of...

  3. 48 CFR 352.237-72 - Crime Control Act-requirement for background checks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Crime Control Act... and Clauses 352.237-72 Crime Control Act—requirement for background checks. As prescribed in 337.103-70(c), the Contracting Officer shall insert the following clause: Crime Control Act of...

  4. 29 CFR 4.117 - Work subject to requirements of Walsh-Healey Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Work subject to requirements of Walsh-Healey Act. 4.117 Section 4.117 Labor Office of the Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Specific Exclusions § 4.117 Work subject...

  5. 32 CFR 505.14 - Recordkeeping requirements under the Privacy Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Recordkeeping requirements under the Privacy Act. 505.14 Section 505.14 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.14 Recordkeeping...

  6. 78 FR 32547 - Loan Originator Compensation Requirements Under the Truth in Lending Act (Regulation Z...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... PROTECTION 12 CFR Part 1026 RIN 3170-AA37 Loan Originator Compensation Requirements Under the Truth in... Compensation Requirements under the Truth in Lending Act (Regulation Z) Final Rule, issued on January 20, 2013...\\ One of these final rules was the Loan Originator Compensation Requirements Under the Truth in...

  7. The Clean Air Act`s enforcement ace: An overview of EPA`s credible evidence rule

    SciTech Connect

    Paul, P.J.

    1997-12-31

    The 1990 Clean Air Act ({open_quotes}CAA{close_quotes}) amendments included numerous provisions directing EPA to require owners or operators to conduct enhanced monitoring and to make compliance certifications. These provisions contained in both those Title V (Operating Permits) and Title VII (Enforcement) of those amendments. Section 503(b)(2) of the amended CAA requires at least annual certifications of compliance with permit requirements and prompt reporting of any deviations from such requirements. Section 114(a)(3) of the CAA requires EPA to promulgate rules on enhanced monitoring and compliance certifications. On October 23, 1993, EPA proposed its {open_quotes}enhanced monitoring{close_quotes} rule. The enhanced monitoring proposal also included the Conceptual approach of using {open_quotes}presumptively credible evidence{close_quotes} in enforcement actions. Further, this proposal also would have allowed the use of {open_quotes}credible evidence,{close_quotes} other than reference or compliance test data to establish noncompliance in an enforcement action. In approximately three weeks, EPA is scheduled to republish as a final rule, the credible evidence provisions of the original enhanced monitoring rule with apparently minor revisions. This paper briefly summarizes the history, status, and likely impact EPA`s {open_quotes}any credible evidence{close_quotes} ({open_quotes}ACE{close_quotes}) rule.

  8. PRN 93-5: Labeling Requirements of the Clean Air Act

    EPA Pesticide Factsheets

    A regulation under the Clean Air Act requires a warning statement on products (including pesticide products) manufactured with or containing Class I ozone-depleting substances, including chlorofluorocarbons, methyl chloroform and carbon tetrachloride.

  9. 32 CFR 505.14 - Recordkeeping requirements under the Privacy Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... under the Privacy Act. (a) AR 25-400-2, The Army Records Information Management System (ARIMS). To maintain privacy records are required by the Army Records Information Management System (ARIMS) to...

  10. 32 CFR 505.14 - Recordkeeping requirements under the Privacy Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... under the Privacy Act. (a) AR 25-400-2, The Army Records Information Management System (ARIMS). To maintain privacy records are required by the Army Records Information Management System (ARIMS) to...

  11. 32 CFR 505.14 - Recordkeeping requirements under the Privacy Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... under the Privacy Act. (a) AR 25-400-2, The Army Records Information Management System (ARIMS). To maintain privacy records are required by the Army Records Information Management System (ARIMS) to...

  12. 32 CFR 505.14 - Recordkeeping requirements under the Privacy Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... under the Privacy Act. (a) AR 25-400-2, The Army Records Information Management System (ARIMS). To maintain privacy records are required by the Army Records Information Management System (ARIMS) to...

  13. Report: Leaking Underground Storage Tank Recovery Act Grants Contained Requirements but Priority Lists Need More Oversight

    EPA Pesticide Factsheets

    Report #11-R-0018, November 22, 2010. While the Recovery Act grants we reviewed contained most of the requirements specified in Agency regulations and guidance, there were three management control deficiencies with these grants.

  14. An optimized spectral difference scheme for CAA problems

    NASA Astrophysics Data System (ADS)

    Gao, Junhui; Yang, Zhigang; Li, Xiaodong

    2012-05-01

    In the implementation of spectral difference (SD) method, the conserved variables at the flux points are calculated from the solution points using extrapolation or interpolation schemes. The errors incurred in using extrapolation and interpolation would result in instability. On the other hand, the difference between the left and right conserved variables at the edge interface will introduce dissipation to the SD method when applying a Riemann solver to compute the flux at the element interface. In this paper, an optimization of the extrapolation and interpolation schemes for the fourth order SD method on quadrilateral element is carried out in the wavenumber space through minimizing their dispersion error over a selected band of wavenumbers. The optimized coefficients of the extrapolation and interpolation are presented. And the dispersion error of the original and optimized schemes is plotted and compared. An improvement of the dispersion error over the resolvable wavenumber range of SD method is obtained. The stability of the optimized fourth order SD scheme is analyzed. It is found that the stability of the 4th order scheme with Chebyshev-Gauss-Lobatto flux points, which is originally weakly unstable, has been improved through the optimization. The weak instability is eliminated completely if an additional second order filter is applied on selected flux points. One and two dimensional linear wave propagation analyses are carried out for the optimized scheme. It is found that in the resolvable wavenumber range the new SD scheme is less dispersive and less dissipative than the original scheme, and the new scheme is less anisotropic for 2D wave propagation. The optimized SD solver is validated with four computational aeroacoustics (CAA) workshop benchmark problems. The numerical results with optimized schemes agree much better with the analytical data than those with the original schemes.

  15. CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.

    PubMed

    Courdavault, Vincent; Thiersault, Martine; Courtois, Martine; Gantet, Pascal; Oudin, Audrey; Doireau, Pierre; St-Pierre, Benoit; Giglioli-Guivarc'h, Nathalie

    2005-04-01

    CaaX-prenyltransferases (CaaX-PTases) catalyse the covalent attachment of isoprenyl groups to conserved cysteine residues located at the C-terminal CaaX motif of a protein substrate. This post-translational modification is required for the function and/or subcellular localization of some transcription factors and components of signal transduction and membrane trafficking machinery. CaaX-PTases, including protein farnesyltransferase (PFT) and type-I protein geranylgeranyltransferase (PGGT-I), are heterodimeric enzymes composed of a common alpha subunit and a specific beta subunit. We have established RNA interference cell lines targeting the beta subunits of PFT and PGGT-I, respectively, in the Catharanthus roseus C20D cell line, which synthesizes monoterpenoid indole alkaloids in response to auxin depletion from the culture medium. In both types of RNAi cell lines, expression of a subset of genes involved in the early stage of monoterpenoid biosynthetic pathway (ESMB genes), including the MEP pathway, is strongly decreased. The role of CaaX-PTases in ESMB gene regulation was confirmed by using the general prenyltransferase inhibitor s-perillyl alcohol (SP) and the specific PFT inhibitor Manumycin A on the wild type line. Furthermore, supplementation of SP inhibited cells with monoterpenoid intermediates downstream of the steps encoded by the ESMB genes restores monoterpenoid indole alkaloids biosynthesis. We conclude that protein targets for both PFT and PGGT-I are required for the expression of ESMB genes and monoterpenoid biosynthesis in C. roseus, this represents a non previously described role for protein prenyltransferase in plants.

  16. 21 CFR 21.71 - Disclosure of records in Privacy Act Record Systems; accounting required.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Systems; accounting required. 21.71 Section 21.71 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... Record Systems to Persons Other Than the Subject Individual § 21.71 Disclosure of records in Privacy Act Record Systems; accounting required. (a) Except as provided in § 21.70, a record about an individual...

  17. 24 CFR 5.212 - Compliance with the Privacy Act and other requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Compliance with the Privacy Act and other requirements. 5.212 Section 5.212 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Disclosure...

  18. 47 CFR 20.15 - Requirements under Title II of the Communications Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CARRIER SERVICES COMMERCIAL MOBILE SERVICES § 20.15 Requirements under Title II of the Communications Act. (a) Commercial mobile radio services providers, to the extent applicable, must comply with sections... mobile radio service providers are not required to: (1) File with the Commission copies of...

  19. 48 CFR 52.204-11 - American Recovery and Reinvestment Act-Reporting Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Reinvestment Act-Reporting Requirements. 52.204-11 Section 52.204-11 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.204-11 American Recovery and Reinvestment Act—Reporting Requirements. As prescribed in 4.1502, insert the following clause: American Recovery and Reinvestment...

  20. 48 CFR 52.204-11 - American Recovery and Reinvestment Act-Reporting Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Reinvestment Act-Reporting Requirements. 52.204-11 Section 52.204-11 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.204-11 American Recovery and Reinvestment Act—Reporting Requirements. As prescribed in 4.1502, insert the following clause: American Recovery and Reinvestment...

  1. 48 CFR 52.204-11 - American Recovery and Reinvestment Act-Reporting Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Reinvestment Act-Reporting Requirements. 52.204-11 Section 52.204-11 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.204-11 American Recovery and Reinvestment Act—Reporting Requirements. As prescribed in 4.1502, insert the following clause: American Recovery and Reinvestment...

  2. 20 CFR 667.300 - What are the reporting requirements for Workforce Investment Act programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR ADMINISTRATIVE PROVISIONS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT...? (a) General. All States and other direct grant recipients must report financial, participant, and... requirements, it must describe those reporting requirements in its State WIA plan. (c) Financial reports....

  3. 24 CFR 5.212 - Compliance with the Privacy Act and other requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Compliance with the Privacy Act and other requirements. 5.212 Section 5.212 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Disclosure...

  4. Emergency Planning and Community Right-to-Know Act (EPCRA) requirements. CERCLA Information Brief

    SciTech Connect

    Dailey, R.

    1993-10-01

    The Emergency Planning and Community Right-to-Know Act (EPCRA), also known as Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), requires regulated facilities to publicly disclose information about the chemicals they store, use, dispose of, or release. The information is used to encourage and support emergency planning for responding to chemical accidents and to provide local governments and the public with information about possible chemical hazards in their communities.

  5. Public Notice Distribution List for CAA Permits, Region 4

    EPA Pesticide Factsheets

    Clean Air Act public notice notification list - subscription form. Currently this is for EPA Region 4 states Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina and Tennessee

  6. 20 CFR 670.420 - Are there any special requirements for enrollment related to the Military Selective Service Act?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... enrollment related to the Military Selective Service Act? 670.420 Section 670.420 Employees' Benefits... there any special requirements for enrollment related to the Military Selective Service Act? (a) Yes... of the Military Selective Service Act (50 U.S.C. App. 451 et seq.) if required; and (b) When a...

  7. 76 FR 14275 - Regulations Issued Under the Export Grape and Plum Act; Revision to the Minimum Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... Service 7 CFR Part 35 Regulations Issued Under the Export Grape and Plum Act; Revision to the Minimum... requirements under the Export Grape and Plum Act. This rule changes the minimum bunch weight requirement for... under authority of the Export Grape and Plum Act, as amended (7 U.S.C. 591-599), hereinafter referred...

  8. 18 CFR Appendix A to Part 380 - Minimum Filing Requirements for Environmental Reports Under the Natural Gas Act

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Requirements for Environmental Reports Under the Natural Gas Act A Appendix A to Part 380 Conservation of Power... Filing Requirements for Environmental Reports Under the Natural Gas Act Environmental Reports Under the Natural Gas Act. Resource Report 1—General Project Description 1. Provide a detailed description...

  9. 21 CFR 108.19 - Establishment of requirements for exemption from section 404 of the act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Establishment of requirements for exemption from section 404 of the act. 108.19 Section 108.19 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EMERGENCY PERMIT CONTROL...

  10. 21 CFR 108.19 - Establishment of requirements for exemption from section 404 of the act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Establishment of requirements for exemption from section 404 of the act. 108.19 Section 108.19 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EMERGENCY PERMIT CONTROL...

  11. 21 CFR 108.19 - Establishment of requirements for exemption from section 404 of the act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Establishment of requirements for exemption from section 404 of the act. 108.19 Section 108.19 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EMERGENCY PERMIT CONTROL...

  12. 21 CFR 108.19 - Establishment of requirements for exemption from section 404 of the act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Establishment of requirements for exemption from section 404 of the act. 108.19 Section 108.19 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EMERGENCY PERMIT CONTROL...

  13. 45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Reporting requirement of the Ethics in Government Act of 1978. 73.735-901 Section 73.735-901 Public Welfare Department of Health and Human Services... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who...

  14. 45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Reporting requirement of the Ethics in Government Act of 1978. 73.735-901 Section 73.735-901 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who...

  15. 45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Reporting requirement of the Ethics in Government Act of 1978. 73.735-901 Section 73.735-901 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who...

  16. 45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Reporting requirement of the Ethics in Government Act of 1978. 73.735-901 Section 73.735-901 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who...

  17. 45 CFR 73.735-901 - Reporting requirement of the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Reporting requirement of the Ethics in Government Act of 1978. 73.735-901 Section 73.735-901 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... Government Ethics; (6) Department Ethics Counselor; and (7) Deputy Ethics Counselors. An employee who...

  18. 76 FR 33413 - Proposed Renewal Without Change; Comment Request; Nine Bank Secrecy Act Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Financial Crimes Enforcement Network Proposed Renewal Without Change; Comment Request; Nine Bank Secrecy Act... be submitted to: Financial Crimes Enforcement Network, P.O. Box 39, Vienna, VA 22183, Attention: BSA... Requirements Comments.'' FOR FURTHER INFORMATION CONTACT: Financial Crimes Enforcement Network,...

  19. 77 FR 27787 - Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements AGENCY: U.S. Customs and Border Protection, Department of Homeland.... SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of Homeland Security will...

  20. 21 CFR 21.71 - Disclosure of records in Privacy Act Record Systems; accounting required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Disclosure of records in Privacy Act Record Systems; accounting required. 21.71 Section 21.71 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... sufficient historical or other value to warrant its continued preservation by the U.S. Government, or to...

  1. 21 CFR 21.71 - Disclosure of records in Privacy Act Record Systems; accounting required.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Disclosure of records in Privacy Act Record Systems; accounting required. 21.71 Section 21.71 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... sufficient historical or other value to warrant its continued preservation by the U.S. Government, or to...

  2. 21 CFR 21.71 - Disclosure of records in Privacy Act Record Systems; accounting required.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Disclosure of records in Privacy Act Record Systems; accounting required. 21.71 Section 21.71 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... sufficient historical or other value to warrant its continued preservation by the U.S. Government, or to...

  3. 21 CFR 21.71 - Disclosure of records in Privacy Act Record Systems; accounting required.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Disclosure of records in Privacy Act Record Systems; accounting required. 21.71 Section 21.71 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... sufficient historical or other value to warrant its continued preservation by the U.S. Government, or to...

  4. 47 CFR 20.15 - Requirements under Title II of the Communications Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CARRIER SERVICES COMMERCIAL MOBILE RADIO SERVICES § 20.15 Requirements under Title II of the Communications Act. (a) Commercial mobile radio services providers, to the extent applicable, must comply with....814 and 43.21 of this chapter; except that commercial radio service providers that offer...

  5. 76 FR 41434 - Removal of Certain Requirements Related to the Prescription Drug Marketing Act; Opportunity for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 203 Removal of Certain Requirements Related to the Prescription Drug Marketing Act; Opportunity for Public Comment AGENCY: Food and Drug Administration, HHS. ACTION: Proposed rule. SUMMARY: The Food and Drug Administration (FDA) is proposing...

  6. The Reasonable Accommodation Requirements of Section 504 of the Rehabilitation Act.

    ERIC Educational Resources Information Center

    Wenkart, Ronald D.

    1990-01-01

    The reasonable accommodation requirements of Section 504 of the Rehabilitation Act of 1973 have recently been applied to public schools. Among the rulings were the provision of a sign language interpreter to hearing-impaired parents and the allowance of a service dog onto a school campus. (MLF)

  7. EVALUATION OF A PROTOCOL FOR DRINKING WATER TREATMENT DATA REQUIRED BY THE FOOD QUALITY PROTECTION ACT

    EPA Science Inventory

    Under the Food Quality Protection Act (FQPA), the USEPA Office of Pesticide Programs (OPP) considers drinking water as a route for pesticide exposure in its human health risk assessments, and may require data on the fate of a pesticide in drinking water be supplied to OPP by the ...

  8. 48 CFR 952.226-72 - Energy Policy Act subcontracting goals and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.226-72 Energy Policy Act subcontracting goals and reporting requirements. As... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Energy Policy...

  9. 48 CFR 952.226-72 - Energy Policy Act subcontracting goals and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.226-72 Energy Policy Act subcontracting goals and reporting requirements. As... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Energy Policy...

  10. 21 CFR 108.19 - Establishment of requirements for exemption from section 404 of the act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Establishment of requirements for exemption from section 404 of the act. 108.19 Section 108.19 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION EMERGENCY PERMIT CONTROL...

  11. 7 CFR 3575.40 - Equal opportunity and Fair Housing Act requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Equal opportunity and Fair Housing Act requirements. 3575.40 Section 3575.40 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GENERAL Community Programs Guaranteed Loans § 3575.40...

  12. 7 CFR 3575.40 - Equal opportunity and Fair Housing Act requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Equal opportunity and Fair Housing Act requirements. 3575.40 Section 3575.40 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GENERAL Community Programs Guaranteed Loans § 3575.40...

  13. Electrochemical dechlorination of chloroacetic acids (CAAs) using hemoglobin-loaded carbon nanotube electrode.

    PubMed

    Li, Yu-Ping; Cao, Hong-Bin; Zhang, Yi

    2006-04-01

    Hemoglobin (Hb) was immobilized on carbon nanotube (CNT) electrode to catalyze the dechlorination of chloroacetic acids (CAAs), and the electrocatalytic behaviors of the Hb-loaded electrode for the dechlorination of trichloroacetic acid (TCAA) were studied by cyclic voltammetry and constant-potential electrolysis technique. An Hb-loaded packed-bed flow reactor was also constructed for bioelectrocatalytic dechloriantion of CAAs from drinking water. The results showed that the reduced heme of Hb immobilized on CNT electrode was easily regenerated, and Hb exhibited a stable and high activity for reductive dechlorination of CAAs with significant lowering of overpotential. TCAA could be reduced at -0.450 V (vs. saturated calomel electrode (SCE)) with catalysis of Hb-loaded electrode and its dechlorination was stepwise, following the pathway of TCAA-->dichloroacetic acid (DCAA)-->monochloroacetic acid (MCAA)-->acetic acid. It was also found that all CAAs, e.g., TCAA, DCAA and MCAA, could be dechlorinated completely at -0.450 V. The removal of 30.0 mM TCAA and DCAA is ca. 40% and 31%, respectively, with electrolysis for 100 min at -0.600 V (vs. SCE) using the Hb-loaded packed-bed flow reactor. The dechlorination activities of CAAs follow the decreasing order: TCAA>DCAA>MCAA, and the average current efficiency is over 90%.

  14. Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplements.

    PubMed

    Wolfe, Kelly L; Liu, Rui Hai

    2007-10-31

    A cellular antioxidant activity (CAA) assay for quantifying the antioxidant activity of phytochemicals, food extracts, and dietary supplements has been developed. Dichlorofluorescin is a probe that is trapped within cells and is easily oxidized to fluorescent dichlorofluorescein (DCF). The method measures the ability of compounds to prevent the formation of DCF by 2,2'-azobis(2-amidinopropane) dihydrochloride (ABAP)-generated peroxyl radicals in human hepatocarcinoma HepG2 cells. The decrease in cellular fluorescence when compared to the control cells indicates the antioxidant capacity of the compounds. The antioxidant activities of selected phytochemicals and fruit extracts were evaluated using the CAA assay, and the results were expressed in micromoles of quercetin equivalents per 100 micromol of phytochemical or micromoles of quercetin equivalents per 100 g of fresh fruit. Quercetin had the highest CAA value, followed by kaempferol, epigallocatechin gallate (EGCG), myricetin, and luteolin among the pure compounds tested. Among the selected fruits tested, blueberry had the highest CAA value, followed by cranberry > apple = red grape > green grape. The CAA assay is a more biologically relevant method than the popular chemistry antioxidant activity assays because it accounts for some aspects of uptake, metabolism, and location of antioxidant compounds within cells.

  15. 77 FR 16785 - Approval and Promulgation of Implementation Plans; Alaska: Infrastructure Requirements for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... 110(a)(1) and (2) of the Clean Air Act (CAA) for the National Ambient Air Quality Standard (NAAQS... Clean Air Act (CAA) for the National Ambient Air Quality Standard (NAAQS) promulgated for ozone on July..., 2008 ozone NAAQS, and 2008 lead NAAQS which EPA intends to act on at a later time. This action...

  16. 77 FR 21702 - Approval and Promulgation of Implementation Plans; Idaho: Infrastructure Requirements for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ...)(1) and (2) of the Clean Air Act (CAA) for the National Ambient Air Quality Standard (NAAQS... (2) of the Clean Air Act (CAA) for the National Ambient Air Quality Standard (NAAQS) promulgated for... NAAQS which EPA intends to act on at a later time. EPA is also proposing to approve portions of a...

  17. The actin gene ACT1 is required for phagocytosis, motility, and cell separation of Tetrahymena thermophila.

    PubMed

    Williams, Norman E; Tsao, Che-Chia; Bowen, Josephine; Hehman, Gery L; Williams, Ruth J; Frankel, Joseph

    2006-03-01

    A previously identified Tetrahymena thermophila actin gene (C. G. Cupples and R. E. Pearlman, Proc. Natl. Acad. Sci. USA 83:5160-5164, 1986), here called ACT1, was disrupted by insertion of a neo3 cassette. Cells in which all expressed copies of this gene were disrupted exhibited intermittent and extremely slow motility and severely curtailed phagocytic uptake. Transformation of these cells with inducible genetic constructs that contained a normal ACT1 gene restored motility. Use of an epitope-tagged construct permitted visualization of Act1p in the isolated axonemes of these rescued cells. In ACT1Delta mutant cells, ultrastructural abnormalities of outer doublet microtubules were present in some of the axonemes. Nonetheless, these cells were still able to assemble cilia after deciliation. The nearly paralyzed ACT1Delta cells completed cleavage furrowing normally, but the presumptive daughter cells often failed to separate from one another and later became reintegrated. Clonal analysis revealed that the cell cycle length of the ACT1Delta cells was approximately double that of wild-type controls. Clones could nonetheless be maintained for up to 15 successive fissions, suggesting that the ACT1 gene is not essential for cell viability or growth. Examination of the cell cortex with monoclonal antibodies revealed that whereas elongation of ciliary rows and formation of oral structures were normal, the ciliary rows of reintegrated daughter cells became laterally displaced and sometimes rejoined indiscriminately across the former division furrow. We conclude that Act1p is required in Tetrahymena thermophila primarily for normal ciliary motility and for phagocytosis and secondarily for the final separation of daughter cells.

  18. 2 CFR 176.190 - Award term-Wage rate requirements under Section 1606 of the Recovery Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... RECOVERY AND REINVESTMENT ACT OF 2009, PUBLIC LAW 111-5 Wage Rate Requirements Under Section 1606 of the American Recovery and Reinvestment Act of 2009 § 176.190 Award term—Wage rate requirements under Section... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Award term-Wage rate requirements...

  19. 75 FR 17919 - Submission for OMB Review; American Recovery and Reinvestment Act-One-time Reporting Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ...; American Recovery and Reinvestment Act--One-time Reporting Requirements for Prime Contractors AGENCY... collection requirement concerning the American Recovery and Reinvestment Act--One-time Reporting Requirements... information on those who are to respond, through the use of appropriate technological collection techniques...

  20. Intramolecular triple helix as a model for regular polyribonucleotide (CAA)(n).

    PubMed

    Efimov, Alexander V; Spirin, Alexander S

    2009-10-09

    The regular (CAA)(n) polyribonucleotide, as well as the omega leader sequence containing (CAA)-rich core, have recently been shown to form cooperatively melted and compact structures. In this report, we propose a structural model for the (CAA)(n) sequence in which the polyribonucleotide chain is folded upon itself, so that it forms an intramolecular triple helix. The triple helix is stabilized by hydrogen bonding between bases thus forming coplanar triads, and by stacking interactions between the base triads. A distinctive feature of the proposed triple helix is that it does not contain the canonical double-helix elements. The difference from the known triple helices is that Watson-Crick hydrogen bond pairings do not take place in the interactions between the bases within the base triads.

  1. 78 FR 54828 - Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for the 1997 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ...EPA is proposing to partially approve and partially disapprove State Implementation Plan (SIP) submissions from the State of Wyoming to demonstrate that the SIP meets the infrastructure requirements of the Clean Air Act (CAA) for the National Ambient Air Quality Standards (NAAQS) promulgated for particulate matter less than or equal to 2.5 micrometers ([mu]m) in diameter (PM2.5) on......

  2. 78 FR 54484 - Notice of Lodging of Consent Decree Under the Clean Air Act (CAA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... request and payment of reproduction costs. Please mail your request and payment to: Consent Decree Library... $14.00 (25 cents per page reproduction cost) payable to the United States Treasury. Maureen...

  3. 20 CFR 667.250 - What requirements relate to the enforcement of the Military Selective Service Act?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the Military Selective Service Act? 667.250 Section 667.250 Employees' Benefits EMPLOYMENT AND... enforcement of the Military Selective Service Act? The requirements relating to the enforcement of the Military Selective Service Act are found at WIA section 189(h)....

  4. 75 FR 77561 - Regulations Issued Under the Export Grape and Plum Act; Revision to the Minimum Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Grape and Plum Act; Revision to the Minimum Requirements AGENCY: Agricultural Marketing Service, USDA... under the Export Grape and Plum Act. The proposed action would change the minimum bunch weight...: This proposed rule is issued under authority of the Export Grape and Plum Act, as amended (7 U.S.C....

  5. 77 FR 56565 - Independent Review of Applications Required by the Healthy, Hunger-Free Kids Act of 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Applications Required by the Healthy, Hunger-Free Kids Act of 2010 AGENCY: Food and Nutrition Service, USDA. ACTION: Proposed rule. SUMMARY: In accordance with Section 304 of the Healthy, Hunger-Free Kids Act of... APEC and RORA and the Department, the Healthy, Hunger-Free Kids Act of 2010, Public Law 111-296,...

  6. 77 FR 33635 - Amendment to the Bank Secrecy Act Regulations-Requirement That Clerks of Court Report Certain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ... Financial Crimes Enforcement Network 31 CFR Part 1010 RIN 1506-AB17 Amendment to the Bank Secrecy Act Regulations--Requirement That Clerks of Court Report Certain Currency Transactions AGENCY: Financial Crimes... Financial Transactions Reporting Act of 1970, as amended by the USA PATRIOT Act of 2001 and...

  7. Risk Management Programs under Clean Air Act Section 112(r): Guidance for Implementing Agencies

    EPA Pesticide Factsheets

    Accidental release prevention programs under section 112(r) of the Clean Air Act (CAA) are related to and build on activities under the Emergency Planning and Community Right-to-Know Act, and Occupational Safety and Health Administration standards.

  8. The Health Insurance Portability and Accountability Act: security and privacy requirements.

    PubMed

    Tribble, D A

    2001-05-01

    The security and privacy requirements of the Health Insurance Portability and Accountability Act of 1996 (HIPAA) and their implications for pharmacy are discussed. HIPAA was enacted to improve the portability of health care insurance for persons leaving jobs. A section of the act encourages the use of electronic communications for health care claims adjudication, mandates the use of new standard code sets and transaction sets, and establishes the need for regulations to protect the security and privacy of individually identifiable health care information. Creating these regulations became the task of the Department of Health and Human Services. Regulations on security have been published for comment. Regulations on privacy and the definition of standard transaction sets and code sets are complete. National identifiers for patients, providers, and payers have not yet been established. The HIPAA regulations on security and privacy will require that pharmacies adopt policies and procedures that limit access to health care information. Existing pharmacy information systems may require upgrading or replacement. Costs of implementation nationwide are estimated to exceed $8 billion. The health care community has two years from the finalization of each regulation to comply with that regulation. The security and privacy requirements of HIPAA will require pharmacies to review their practices regarding the storage, use, and disclosure of protected health care information.

  9. Requirements and impacts of the Federal Facility Compliance Act on the Department of Energy

    SciTech Connect

    Chang, L.; Tripp, S.C.

    1993-03-01

    The Federal Facilities Compliance Act (FFCA, the Act) was signed into law on October 6, 1992, primarily as a means of waiving sovereign immunity for federal facilities with respect to requirements under the Resource Conservation and Recovery Act. DOE`s implementation of the FFCA will have significant effects on current and future DOE waste management operations. DOE will need to rethink its strategy in the area of future compliance agreements to ensure commitments and deliverables are made consistent throughout the different DOE facilities. Several types of agreements that address mixed waste land disposal restriction (LDR) compliance have already been signed by both DOE and the regulators. These agreements are in place at the Hanford Reservation, the Savannah River Site, the Oak Ridge Reservation (Oak Ridge National Laboratory, K-25, Y-12), and the Paducah Gaseous Diffusion Plant. The Rocky Flats Agreement is now being renegotiated. Los Alamos National Laboratory, Sandia/Albuquerque National Laboratory, Lawrence Livermore National Laboratory, and Idaho National Engineering Laboratory agreements are in progress. Major components of the FFCA include provisions on: sovereign immunity waiver; cost reimbursements; mixed waste requirements, including inventory reports on mixed waste and treatment capacity and technologies; and plans for the development of treatment capacities and technologies. Each of these components is discussed within this paper.

  10. CFD-CAA Coupled Calculations of a Tandem Cylinder Configuration to Assess Facility Installation Effects

    NASA Technical Reports Server (NTRS)

    Redonnet, Stephane; Lockard, David P.; Khorrami, Mehdi R.; Choudhari, Meelan M.

    2011-01-01

    This paper presents a numerical assessment of acoustic installation effects in the tandem cylinder (TC) experiments conducted in the NASA Langley Quiet Flow Facility (QFF), an open-jet, anechoic wind tunnel. Calculations that couple the Computational Fluid Dynamics (CFD) and Computational Aeroacoustics (CAA) of the TC configuration within the QFF are conducted using the CFD simulation results previously obtained at NASA LaRC. The coupled simulations enable the assessment of installation effects associated with several specific features in the QFF facility that may have impacted the measured acoustic signature during the experiment. The CFD-CAA coupling is based on CFD data along a suitably chosen surface, and employs a technique that was recently improved to account for installed configurations involving acoustic backscatter into the CFD domain. First, a CFD-CAA calculation is conducted for an isolated TC configuration to assess the coupling approach, as well as to generate a reference solution for subsequent assessments of QFF installation effects. Direct comparisons between the CFD-CAA calculations associated with the various installed configurations allow the assessment of the effects of each component (nozzle, collector, etc.) or feature (confined vs. free jet flow, etc.) characterizing the NASA LaRC QFF facility.

  11. 40 CFR 59.1 - Final determinations under Section 183(e)(3)(C) of the CAA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... COMMERCIAL PRODUCTS General § 59.1 Final determinations under Section 183(e)(3)(C) of the CAA. This section identifies the consumer and commercial product categories for which EPA has determined that CTGs will be... paneling coatings; (h) Industrial cleaning solvents; (i) Paper, film, and foil coatings; (j)...

  12. Modeling Requirements for Simulating the Effects of Extreme Acts of Terrorism: A White Paper

    SciTech Connect

    Allen, M.; Hiebert-Dodd, K.; Marozas, D.; Paananen, O.; Pryor, R.J.; Reinert, R.K.

    1998-10-01

    This white paper presents the initial requirements for developing a new computer model for simulating the effects of extreme acts of terrorism in the United States. General characteristics of the model are proposed and the level of effort to prepare a complete written description of the model, prior to coding, is detailed. The model would simulate the decision processes and interactions of complex U. S. systems engaged in responding to and recovering from four types of terrorist incidents. The incident scenarios span the space of extreme acts of terrorism that have the potential to affect not only the impacted area, but also the entire nation. The model would be useful to decision-makers in assessing and analyzing the vulnerability of the nation's complex infrastructures, in prioritizing resources to reduce risk, and in planning strategies for immediate response and for subsequent recovery from terrorist incidents.

  13. EPCRA/CERCLA/CAA §112(r) Consolidated List of Lists – March 2015 Version

    EPA Pesticide Factsheets

    List of Lists was prepared to help firms handling chemicals determine, for a specific chemical, whether they may be subject to the following reporting requirements under Emergency Planning and Community Right-to-Know, CERCLA, and Clean Air Act.

  14. Implementing the Affordable Care Act: Revisiting the ACA's Essential Health Benefits Requirements.

    PubMed

    Giovannelli, Justin; Lucia, Kevin W; Corlette, Sabrina

    2014-10-01

    The Affordable Care Act broadens and strengthens the health insurance benefits available to consumers by requiring insurers to provide coverage of a minimum set of medical services known as "essential health benefits." Federal officials implemented this reform using transitional policies that left many important decisions to the states, while pledging to reassess that approach in time for the 2016 coverage year. This issue brief examines how states have exercised their options under the initial federal essential health benefits framework. We find significant variation in how states have developed their essential health benefits packages, including their approaches to benefit substitution and coverage of habilitative services. Federal regulators should use insurance company data describing enrollees' experiences with their coverage--information called for under the law's delayed transparency requirements--to determine whether states' differing strategies are producing the coverage improvements promised by reform.

  15. 75 FR 44163 - Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ...-AB07 Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of... clarify conditions for industry compliance with the P&S Act and provide for a fairer market place. DATES... fairer market place. We have received comments asking for an extension of the comment period, and...

  16. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009) (a... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal...

  17. Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans.

    PubMed

    Cadiñanos, Juan; Schmidt, Walter K; Fueyo, Antonio; Varela, Ignacio; López-Otín, Carlos; Freije, José M P

    2003-03-15

    Post-translational processing of proteins such as the Ras GTPases, which contain a C-terminal CaaX motif (where C stands for cysteine, a for aliphatic and X is one of several amino acids), includes prenylation, proteolytic removal of the C-terminal tripeptide and carboxy-methylation of the isoprenyl-cysteine residue. In the present study, we report the presence of two distinct CaaX-proteolytic activities in membrane extracts from Caenorhabditis elegans, which are sensitive to EDTA and Tos-Phe-CH(2)Cl (tosylphenylalanylchloromethane; 'TPCK') respectively. A protein similar to the mammalian and yeast farnesylated-proteins converting enzyme-1 (FACE-1)/Ste24p CaaX metalloprotease, encoded by a hypothetical gene (CeFACE-1/C04F12.10) found in C. elegans chromosome I, probably accounts for the EDTA-sensitive activity. An orthologue of FACE-2/Rce1p, the enzyme responsible for the proteolytic maturation of Ras oncoproteins and other prenylated substrates, probably accounts for the Tos-Phe-CH(2)Cl-sensitive activity, even though the gene for FACE-2/Rce1 has not been previously identified in this model organism. We have identified a previously overlooked gene in C. elegans chromosome V, which codes for a 266-amino-acid protein (CeFACE-2) with 30% sequence identity to human FACE-2/Rce1. We show that both CeFACE-1 and CeFACE-2 have the ability to promote production of the farnesylated yeast pheromone a -factor in vivo and to cleave a farnesylated peptide in vitro. These results indicate that CeFACE-1 and CeFACE-2 are bona fide CaaX proteases and support the evolutionary conservation of this proteolytic system in eukaryotes.

  18. Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans.

    PubMed Central

    Cadiñanos, Juan; Schmidt, Walter K; Fueyo, Antonio; Varela, Ignacio; López-Otín, Carlos; Freije, José M P

    2003-01-01

    Post-translational processing of proteins such as the Ras GTPases, which contain a C-terminal CaaX motif (where C stands for cysteine, a for aliphatic and X is one of several amino acids), includes prenylation, proteolytic removal of the C-terminal tripeptide and carboxy-methylation of the isoprenyl-cysteine residue. In the present study, we report the presence of two distinct CaaX-proteolytic activities in membrane extracts from Caenorhabditis elegans, which are sensitive to EDTA and Tos-Phe-CH(2)Cl (tosylphenylalanylchloromethane; 'TPCK') respectively. A protein similar to the mammalian and yeast farnesylated-proteins converting enzyme-1 (FACE-1)/Ste24p CaaX metalloprotease, encoded by a hypothetical gene (CeFACE-1/C04F12.10) found in C. elegans chromosome I, probably accounts for the EDTA-sensitive activity. An orthologue of FACE-2/Rce1p, the enzyme responsible for the proteolytic maturation of Ras oncoproteins and other prenylated substrates, probably accounts for the Tos-Phe-CH(2)Cl-sensitive activity, even though the gene for FACE-2/Rce1 has not been previously identified in this model organism. We have identified a previously overlooked gene in C. elegans chromosome V, which codes for a 266-amino-acid protein (CeFACE-2) with 30% sequence identity to human FACE-2/Rce1. We show that both CeFACE-1 and CeFACE-2 have the ability to promote production of the farnesylated yeast pheromone a -factor in vivo and to cleave a farnesylated peptide in vitro. These results indicate that CeFACE-1 and CeFACE-2 are bona fide CaaX proteases and support the evolutionary conservation of this proteolytic system in eukaryotes. PMID:12487630

  19. 77 FR 28790 - Medical Loss Ratio Requirements Under the Patient Protection and Affordable Care Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... Protection and Affordable Care Act AGENCY: Centers for Medicare & Medicaid Services (CMS), HHS. ACTION: Final... Care Act (Pub. L. 111-148) was enacted on March 23, 2010; the Health Care and Education Reconciliation... collectively as the Affordable Care Act. The Affordable Care Act reorganizes, amends, and adds to...

  20. 129Xe nuclear magnetic resonance studies of xenon in zeolite CaA

    NASA Astrophysics Data System (ADS)

    Jameson, Cynthia J.; Jameson, A. Keith; Gerald, Rex, II; de Dios, Angel C.

    1992-02-01

    The average 129Xe nuclear magnetic resonance (NMR) chemical shift for xenon atoms in alpha cages of zeolite CaA is observed in a single peak dependent on xenon loading (=0.5-8.9 Xe atoms/alpha cage) and temperature (240-360 K). The general increase of the shift with increasing average number of xenon atoms per alpha cage is shown to be due largely to the changing distribution of occupancies with increasing , coupled with increasing increments in the chemical shifts of Xen with increasing n. Except at the highest loadings, the results obtained for xenon in CaA are predicted nicely on the basis of δav(T)=(1/)Σnnδn(T)Pn (,T), where the fractions Pn of alpha cages containing n Xe atoms are imported from the Pn measured in xenon in zeolite NaA. The high loading data in CaA are interpreted in terms of contributions to the average 129Xe chemical shifts associated with xenon atoms in the window positions.

  1. Electron transfer kinetics of caa3 oxidase from Bacillus stearothermophilus: a hypothesis for thermophilicity.

    PubMed Central

    Giuffrè, A; Watmough, N J; Giannini, S; Brunori, M; Konings, W N; Greenwood, C

    1999-01-01

    The O2 reaction and the reverse electron transfer of the thermophilic caa3 terminal oxidase of Bacillus stearothermophilus have been studied by laser flash-photolysis. The results show that both reactions, although studied at a temperature of 20 degreesC, far from the optimal temperature of > 60 degreesC for caa3, follow a kinetic behavior essentially identical to that observed with the electrostatic complex between mammalian cyt c and cyt c oxidase. In the O2 reaction cyt a and cyt a3 are very quickly oxidized; cyt a is then re-reduced via CuA, whereas cyt c oxidation is apparently rate-limited by the oxidation of CuA. Upon photodissociation of the mixed valence-CO caa3, reverse electron transfer from the binuclear center to cyt a3+ (tau1 = 3 micros) and CuA2+ (tau2 = 64 micros) is observed, while cyt c is not reduced by any detectable level. These results seem to rule out accounting for enzymatic thermophilicity by altered kinetics of intramolecular electron transfer involving the cyt center in the reduced configuration, which is very fast. On the basis of these results and previous data, we propose that thermophilicity involves an increased activation barrier for the reduction of cyt a3-CuB in the configuration typical of the oxidized site. PMID:9876155

  2. Mixed Waste Integrated Program: Demonstrating technologies to meet the requirements of the Federal Facility Compliance Act

    SciTech Connect

    Berry, J.B.

    1994-07-01

    Mixed waste is defined as ``waste contaminated with chemically hazardous [governed by the Resource Conservation and Recovery Act (RCRA)] and radioactive species [governed by US Department of energy (DOE) orders].`` The Mixed Waste Integrated Program (MWIP) is responding to the need for DOE mixed-waste treatment technologies tat meet these dual regulatory requirements. MWIP is developing emerging and innovative treatment technologies to determine process feasibility. Technology demonstrations of fixed-hearth plasma arc and vitrification systems will be used to determine whether these processes are superior to existing technologies in reducing risk, minimizing life-cycle cost, and improving process performance. MWIP also provides a forum for stakeholder and customer involvement in the technology development process.

  3. Title III list of lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and section 112(r) of the Clean Air Act, as amended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990

    SciTech Connect

    Not Available

    1994-06-01

    The consolidated chemical list includes chemicals subject to reporting requirements under Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), also known as the Emergency Planning and Community Right-to-Know Act (EPCRA), and chemicals listed under section 112(r) of Title III the Clean Air Act (CAA) Amendments of 1990. This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 313 of SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. Separate lists are also provided of Resource Conservation and Recovery Act (RCRA) waste streams and unlisted hazardous wastes, and of radionuclides reportable under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). These lists should be used as reference tool, not as a definitive source of compliance information. The chemicals on the consolidated list are ordered by Chemical Abstract Service (CAS) registry number. Categories of chemicals, which do not have CAS registry numbers, but which are cited under CERCLA, EPCRA section 313, and the CAA, are placed at the end of the list. More than one chemical name may be listed for one CAS number, because the same chemical may appear on different lists under different names.

  4. The caa(3) terminal oxidase of Rhodothermus marinus lacking the key glutamate of the D-channel is a proton pump.

    PubMed

    Pereira, M M; Verkhovskaya, M L; Teixeira, M; Verkhovsky, M I

    2000-05-30

    The thermohalophilic bacterium Rhodothermus marinus expresses a caa(3)-type dioxygen reductase as one of its terminal oxidases. The subunit I amino acid sequence shows the presence of all the essential residues of the D- and K-proton channels, defined in most heme-copper oxidases, with the exception of the key glutamate residue located in the middle of the membrane dielectric (E278 in Paracoccus denitrificans). On the basis of homology modeling studies, a tyrosine residue (Y256, R. marinus numbering) has been proposed to act as a functional substitute [Pereira, M. M., Santana, M., Soares, C. M., Mendes, J., Carita, J. N., Fernandes, A. S., Saraste, M., Carrondo, M. A., and Teixeira, M. (1999) Biochim. Biophys. Acta 1413, 1-13]. Here, R. marinus caa(3) oxidase was reconstituted in liposomes and shown to operate as a proton pump, translocating protons from the cytoplasmic side of the bacterial inner membrane to the periplasmatic space with a stoichiometry of 1H(+)/e(-), as in the case in heme-copper oxidases that contain the glutamate residue. Possible mechanisms of proton transfer in the D-channel with the participation of the tyrosine residue are discussed. The observation that the tyrosine residue is conserved in several other members of the heme-copper oxidase superfamily suggests a common alternative mode of action for the D-channel.

  5. 40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm...

  6. 40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm...

  7. 40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm...

  8. Microcomputer Integrated Library System (MILS). The Online Integrated Technical Information Center System at US Army Concepts Analysis Agency (CAA).

    DTIC Science & Technology

    1986-09-01

    Integrated Library System (MILS) 1. Attached is "Microcomputer Integrated Library System (MILS), a technical paper on some recent work accomplished...8217 irectorate War"w~umIFT 77 MTT-ZF . - ~ ~ MILS: THE ONLINE INTEGRATED TECHNICAL STUDY CAA INFORMATION CENTER SYSTEM AT CAASMMR sm’ 0A CAA-TP-8610 THE...REASON FOR PERFORMING THE STUDY was to determine the most efficient and effective method of evolving from a two-system (manual and batch) environ- ment

  9. 78 FR 46549 - Approval and Promulgation of Implementation Plans; Idaho: State Board Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... infrastructure requirements of the CAA for the 1997 ozone National Ambient Air Quality ] Standards (NAAQS). If... revised NAAQS for ozone.\\1\\ This action triggered a requirement for states to submit an infrastructure SIP...), which requires that infrastructure SIPs meet the requirements of CAA section 128, and that we...

  10. 45 CFR 150.207 - Procedure for determining that a State fails to substantially enforce PHS Act requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States Are Failing To Substantially... enforce PHS Act requirements. Sections 150.209 through 150.219 describe the procedures CMS follows...

  11. 45 CFR 150.207 - Procedure for determining that a State fails to substantially enforce PHS Act requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for Determining Whether States Are Failing To Substantially... enforce PHS Act requirements. Sections 150.209 through 150.219 describe the procedures CMS follows...

  12. 75 FR 17918 - Submission for OMB Review; American Recovery and Reinvestment Act-One-Time Reporting Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ...; American Recovery and Reinvestment Act--One-Time Reporting Requirements for First-Tier Subcontractors...--One-time Reporting Requirements for First-tier Subcontractors. A request for public comments was... technological collection techniques or other forms of information technology. DATES: Submit comments on...

  13. Notification: Evaluation of Enforcement Decree Compliance for Selected Clean Air Act Sources

    EPA Pesticide Factsheets

    Project #OPE-FY14-0016, May 22, 2014. The Office of Inspector General (OIG) plans to begin the preliminary research phase of an evaluation of enforcement decree compliance for selected Clean Air Act (CAA) sources.

  14. Lone Star Industries, Inc. (Buzzi), Clean Air Act Settlement

    EPA Pesticide Factsheets

    Buzzi agreed to invest approximately $1 million in pollution control technology that will protect public health and resolve violations of the CAA. The settlement requires that Buzzi spend approximately $1.7 million on an environmental mitigation project

  15. Intergovernmental relations inherent in the Energy Management Partnership Act: a workshop on information requirements

    SciTech Connect

    Hoop, W.J.; Edelson, E.

    1980-02-01

    This paper summarizes the results of the first of three workshops that were planned to assess the information needed by the Office of Conservation and Solar Energy (CS) to effectively evaluate the pending Energy Management Partnership Act (EMPA); the workshop concentrated on issues of the EMPA hierarchical partnership. The approach utilized offers two major benefits to CS. First, by considering the problem of program evaluation while EMPA is still in the planning stage, this study identifies any baseline information that should be collected prior to implementation of EMPA, and also provides CS with the opportunity to include evaluation considerations in the operating guidelines for the program. Second, by identifying the potential problems and benefits inherent in EMPA and then identifying the information necessary to evaluate these problems and benefits, information requirements tied to the reasons for needing that information are generated, rather than a long unrelated laundry list of information requirements. Drafting of EMPA is not yet complete. When the term EMPA is used here, it refers to a set of bills that are presently being melded together. The original EMPA bill, which originated in DOE, was designed to expand the role of state and local governments in achieving national energy goals. Specifically, EMPA would provide a total of $110 million annually to state and local governments over a five year period to (1) develop an overall state energy plan, (2) consolidate three existing federal energy grant programs, (3) allow the secretary to fund directly innovative projects at the local level, and (4) provide additional assistance to states to cover the administrative costs of existing energy programs. Other bills, which may be passed in conjuncttion with EMPA or incorporated into EMPA, place additional emphasis on the local level by allocating as much as $400 million annually to local governments.

  16. Cluster Ion Spectrometry (CIS) Data in the Cluster Active Archive (CAA)

    NASA Astrophysics Data System (ADS)

    Dandouras, I.; Barthe, A.; Penou, E.; Brunato, S.; Rème, H.; Kistler, L. M.; Bavassano-Cattaneo, M. B.; Blagau, A.

    The Cluster Active Archive (CAA) aims at preserving the four Cluster spacecraft data, so that they are usable in the long-term by the scientific community as well as by the instrument team PIs and Co-Is. This implies that the data are filed together with the descriptive and documentary elements making it possible to select and interpret them. The CIS (Cluster Ion Spectrometry) experiment is a comprehensive ionic plasma spectrometry package onboard the four Cluster spacecraft, capable of obtaining full three-dimensional ion distributions (about 0-40 keV/e) with a time resolution of one spacecraft spin (4 s) and with mass-per-charge composition determination. The CIS package consists of two different instruments, a Hot Ion Analyser (HIA) and a time-of-flight ion Composition Distribution Function (CODIF) analyser, plus a sophisticated dual-processor based instrument control and data processing system (DPS). For the archival of the CIS data a multi-level approach has been adopted. The CAA archival includes processed raw data (Level 1 data), moments of the ion distribution functions (Level 2 data), and calibrated high-resolution data in a variety of physical units (Level 3 data). The latter are 3-D ion distribution functions. In addition, a software package has been developed to allow the CAA user to interactively calculate partial or total moments of the ion distributions. The CIS data archive includes also experiment documentation, graphical products for browsing through the data, and data caveats. Given the complexity of an ion spectrometer, and the variety of its operational modes, each one being optimised for a different magnetospheric region or measurement objective, consultation of the data caveats by the end user will always be a necessary step in the data analysis.

  17. 75 FR 55663 - Requirements for Federal Funding Accountability and Transparency Act Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-14

    ... services of a third party to help in designing public service announcements or developing educational... that allows the public to find, review, and submit comments on documents that agencies have published... of Public Law 110-252, hereafter referred to as ``the Transparency Act'' or ``the Act'')....

  18. 48 CFR 952.226-72 - Energy Policy Act subcontracting goals and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the Small Business Act (15 U.S.C. 632), that are owned and controlled by individuals who are both socially and economically disadvantaged within the meaning of section 8(d) of the Small Business Act (15 U... paragraph (b) of this clause shall be included as an addendum to Standard Form (SF) 294,...

  19. 48 CFR 952.226-72 - Energy Policy Act subcontracting goals and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the Small Business Act (15 U.S.C. 632), that are owned and controlled by individuals who are both socially and economically disadvantaged within the meaning of section 8(d) of the Small Business Act (15 U... included as an addendum to Standard Form (SF) 294, Subcontracting Report for Individual Contracts,...

  20. MEETING THE REQUIREMENTS OF THE U.S. SAFE DRINKING WATER ACT: THE ROLE OF TECHNOLOGY

    EPA Science Inventory

    The passage of the U.S. Safe Drinking Water Act (SDWA) in 1974 has had a major impact on the way water is treated and delivered in the United States. The Act established national drinking water regulations for more than 170,000 public drinking water systems serving over 250 mill...

  1. Relationship of cytochrome caa sub 3 from Thermus thermophilus to other heme- and copper-containing terminal oxidases

    SciTech Connect

    Mather, M.W.; Springer, P.; Fee, J.A.

    1990-01-01

    Cytochrome oxidases are a key component of the energy metabolism of most aerobic organisms from mammals to bacteria. They are the final enzyme of the membrane associated respiratory chain responsible for converting the chemical energy of reduced substrates to a transmembrane electrochemical potential, which issused by the cell for a wide variety of energy-requiring processes. The most widely studied oxidase is the cytochrome c oxidase of the mammalian mitochondrion. This complex, integral membrane protein contains 13 subunits and four canonical metal centers: heme center a and a{sub 3}; copper centers CU{sub A} and CU{sub B}. It is responsible for electron transfer from reduced chytochrome c to dioxygen with the concomitant reduction of dioxygen to water and the coupled vectorial transfer of protons across the mitochondrial membrane. In this communication we will describe preliminary results of DNA sequencing experiments with the cytochrome caa{sub 3} oxidase, initially undertaken to determine the nature of the subunits of this oxidase and shed light on the distribution of the metal centers. We will speculate on oxidase gene and protein structures and evolutionary relationships in the light of these results and recent sequencing results from other groups. 47 refs., 4 figs., 1 tab.

  2. Infrared and SEM analyses of polyethyleneglycol-400 adsorbed on zeolites NaA, CaA, NaX and NaY

    NASA Astrophysics Data System (ADS)

    Öztürk, Nuri; Ucun, Fatih; Didem Muhtar, A.; Bahçeli, Semiha

    2009-03-01

    The adsorption of polyethyleneglycol-400 (PEG-400) on zeolites NaA, CaA, NaX and NaY have been investigated by using FT-IR spectroscopy and scanning electron microscopic (SEM) analyses. The spectral data have indicated that the source of adsorption of the PEG-400 on the mentioned zeolites is the interaction between the (OH) group of the liquid adsorbent and the surface silanol groups of the zeolites by means of a hydrogen bond. Shortly, the PEG binds with the silanol groups through the hydrogen bonding where the ethereal oxygen acts as a hydrogen bond accepter. A part of the PEG molecule remains adsorbed on the surface and the rest part remains protruded. So, the most of the silanol groups on the zeolites are masked by the PEG-400.

  3. Least-Squares Spectral Element Solutions to the CAA Workshop Benchmark Problems

    NASA Technical Reports Server (NTRS)

    Lin, Wen H.; Chan, Daniel C.

    1997-01-01

    This paper presents computed results for some of the CAA benchmark problems via the acoustic solver developed at Rocketdyne CFD Technology Center under the corporate agreement between Boeing North American, Inc. and NASA for the Aerospace Industry Technology Program. The calculations are considered as benchmark testing of the functionality, accuracy, and performance of the solver. Results of these computations demonstrate that the solver is capable of solving the propagation of aeroacoustic signals. Testing of sound generation and on more realistic problems is now pursued for the industrial applications of this solver. Numerical calculations were performed for the second problem of Category 1 of the current workshop problems for an acoustic pulse scattered from a rigid circular cylinder, and for two of the first CAA workshop problems, i. e., the first problem of Category 1 for the propagation of a linear wave and the first problem of Category 4 for an acoustic pulse reflected from a rigid wall in a uniform flow of Mach 0.5. The aim for including the last two problems in this workshop is to test the effectiveness of some boundary conditions set up in the solver. Numerical results of the last two benchmark problems have been compared with their corresponding exact solutions and the comparisons are excellent. This demonstrates the high fidelity of the solver in handling wave propagation problems. This feature lends the method quite attractive in developing a computational acoustic solver for calculating the aero/hydrodynamic noise in a violent flow environment.

  4. Maintaining Student Records and Meeting Confidentiality Requirements under the Family Education Rights and Privacy Act (FERPA), Individuals with Disability Education Act (IDEA), Section 504 of the Rehabilitation Act (504). A Primer for Educators

    ERIC Educational Resources Information Center

    Copenhaver, John

    2006-01-01

    An important federal statute impacting student records is the Family Educational Rights and Privacy Act (FERPA), enacted to ensure student/parent access to education records and to limit disclosures to others for unauthorized purposes. FERPA Regulations set forth the basic federal records retention and destruction requirements. The records of…

  5. 2 CFR 176.50 - Award term-Reporting and registration requirements under section 1512 of the Recovery Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Award term-Reporting and registration requirements under section 1512 of the Recovery Act. 176.50 Section 176.50 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET...

  6. 2 CFR 176.50 - Award term-Reporting and registration requirements under section 1512 of the Recovery Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Award term-Reporting and registration requirements under section 1512 of the Recovery Act. 176.50 Section 176.50 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET...

  7. 2 CFR 176.50 - Award term-Reporting and registration requirements under section 1512 of the Recovery Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Award term-Reporting and registration requirements under section 1512 of the Recovery Act. 176.50 Section 176.50 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET...

  8. 75 FR 35338 - Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ..., USDA. ACTION: Proposed rule. SUMMARY: The Department of Agriculture (USDA), Grain Inspection, Packers..., the P&S Act imposes a variety of more specific limitations and requirements. In particular, it... also sets forth procedures for enforcement actions before the Secretary \\13\\ and private...

  9. 16 CFR 803.30 - Formal and informal interpretations of requirements under the Act and the rules.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Formal and informal interpretations of requirements under the Act and the rules. 803.30 Section 803.30 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST...

  10. 16 CFR 803.30 - Formal and informal interpretations of requirements under the Act and the rules.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Formal and informal interpretations of requirements under the Act and the rules. 803.30 Section 803.30 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST...

  11. 16 CFR 803.30 - Formal and informal interpretations of requirements under the Act and the rules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Formal and informal interpretations of requirements under the Act and the rules. 803.30 Section 803.30 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST...

  12. 16 CFR 803.30 - Formal and informal interpretations of requirements under the Act and the rules.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Formal and informal interpretations of requirements under the Act and the rules. 803.30 Section 803.30 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST...

  13. 16 CFR 803.30 - Formal and informal interpretations of requirements under the Act and the rules.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Formal and informal interpretations of requirements under the Act and the rules. 803.30 Section 803.30 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST...

  14. 2 CFR 176.50 - Award term-Reporting and registration requirements under section 1512 of the Recovery Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Award term-Reporting and registration requirements under section 1512 of the Recovery Act. 176.50 Section 176.50 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS Reserved AWARD TERMS FOR...

  15. 2 CFR 176.50 - Award term-Reporting and registration requirements under section 1512 of the Recovery Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Award term-Reporting and registration requirements under section 1512 of the Recovery Act. 176.50 Section 176.50 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET...

  16. 2 CFR 176.190 - Award term-Wage rate requirements under Section 1606 of the Recovery Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Award term-Wage rate requirements under Section 1606 of the Recovery Act. 176.190 Section 176.190 Grants and Agreements OFFICE OF MANAGEMENT AND... are in excess of $2,000 for construction, alteration or repair (including painting and decorating)....

  17. 15 CFR 744.11 - License requirements that apply to entities acting contrary to the national security or foreign...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Secretary of State as having repeatedly provided support for acts of international terrorism. (3... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false License requirements that apply to... Section 744.11 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade...

  18. Clean Air Act: Senate mulls revision bill

    SciTech Connect

    Fairley, P.

    1995-12-13

    Senator Lauch Faircloth (R., NC) has circulated a draft summary of possible revisions of the Clean Air Act (CAA). Chemical industry sources say the proposal would provide some regulatory relief but fear that supporting Faircloth could jeopardize their relationship with EPA. Faircloth`s proposal addresses various controversial aspect of CAA`s Title V permit program including the monitoring and permit modification provisions. The proposal would also define a facility`s {open_quotes}potential to emit,{close_quotes} upon which Title V permits are based. In the past year EPA has substantially revised its Title V program to address complaints from industry, the states, and Congress that the monitoring and modification provisions were too burdensome.

  19. 40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified...

  20. 40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified...

  1. 40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified...

  2. 40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified...

  3. 40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified...

  4. 75 FR 67719 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... take final action under section 110(k) of the Act on Imperial County Air Pollution Control District... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency... section 113(g) of the Clean Air Act, as amended (CAA or the Act), 42 U.S.C. 7413(g), notice is...

  5. Report: EPA Relying on Existing Clean Air Act Regulations to Reduce Atmospheric Deposition to the Chesapeake Bay and its Watershed

    EPA Pesticide Factsheets

    Report #2007-P-00009, February 28, 2007. EPA’s Chesapeake Bay Program Office is relying on anticipated nitrogen deposition reductions from Clean Air Act (CAA) regulations already issued by EPA, combined with other non-air sources' anticipated reductions.

  6. Notification: Background Investigation Services EPA’s Efforts to Incorporate Environmental Justice Into Clean Air Act Inspections for Air Toxics

    EPA Pesticide Factsheets

    Project #OPE-FY14-0017, March 7, 2014. The OIG plans to begin the preliminary research phase of an evaluation of the EPA's efforts to incorporate environmental justice into Clean Air Act (CAA) inspections for air toxics.

  7. Implementation of the Methamphetamine Anti-Proliferation Act; thresholds for retailers and for distributors required to submit mail order reports; changes to mail order reporting requirements. Final rule.

    PubMed

    2003-10-07

    This regulation implements the new threshold requirements and mail order reporting requirements of the Methamphetamine Anti-Proliferation Act of 2000 (MAPA), which was enacted on October 17, 2000. DEA is amending its regulations to reduce the thresholds for pseudoephedrine and phenylpropanolamine for retail distributors and for distributors required to submit mail order reports. Also, DEA is amending its regulations to require mail order reports for certain export transactions. DEA is codifying exemptions from the mail order reporting requirements for certain distributions to nonregulated persons and certain export transactions. This rule is consistent with the intent of MAPA to prevent the diversion of drug products to the clandestine manufacture of methamphetamine and amphetamine, and simultaneously reduce the industry reporting burden.

  8. Legal requirements for donating and retaining organs: the Human Tissue Act.

    PubMed

    Griffith, Richard

    2006-10-01

    The Human Tissue Act 2004 came into force on 1 September 2006 and introduced significant changes in the way human body parts, tissue and organs are removed, stored and used. The Act seeks to remedy the poor availability of organs for transplant caused in part by laws that date back to the 17th Century and to right the concerns raised by the Liverpool Children's Inquiry that revealed widespread retention of organs by hospitals without permission. In this article Richard Griffith describes how consent is now the driving force underpinning such activity and how the wishes of the patient remain paramount even after death. He also outlines how the Human Tissue Authority will licence and inspect activities involving human tissue under the Act and discuss how the new law will affect district nurse practice.

  9. Department of Defense Requirements in the Superfund Amendments and Reauthorization Act.

    DTIC Science & Technology

    This report outlines Superfund Amendments and Reauthorization Act (SARA) effects on the Office of the Secretary of Defense (OSD) in general and...personnel. The report gives reporting guidance to DoD installations. Keywords: Installation restoration program, CERCLA (Comprehensive Environmental

  10. Workforce Investment Act: Better Guidance Needed To Address Concerns over New Requirements. Report to Congressional Requesters.

    ERIC Educational Resources Information Center

    Nilsen, Sigurd R.

    In an effort to assess what progress states and localities are making in implementation of the Workforce Investment Act (WIA) of 1998, a study identified three issues of particular concern: (1) mandatory partners' participation in the one-stops; (2) job seekers' ability to receive enhanced choices for training; and (3) private-sector participation…

  11. [High voltage objects and radiocommunication investments in view of requirements of the environmental protection act].

    PubMed

    Szuba, Marek

    2006-01-01

    This paper presents the most important elements of the localization procedure of high voltage overhead lines and substations and radiocommunication objects which are the source of electromagnetic fields. These fields are perceived as a major threat to human health. The point of departure to make a choice of investments is the special classification of technical installations described in one of the executive directive issued by virtue of the Environmental Protection Act. This special executive directive enumerates a lot of technical objects (installation), classified in the group of investments which have significant impact on the environment and some objects which could be classified in this group. For all this technical installations (e.g., overhead high voltage power lines) the provisions of the Environmental Protection Act impose an obligation to take particular steps to assure transparency of the environmental protection procedures, transborder procedures and the protection of areas included in the Natura 2000 network.

  12. Energy Security Requires Diversity: An Argument for The Defense Production Act Title III Biofuel Initiative

    DTIC Science & Technology

    2013-06-19

    the United States . 125 The President is further authorized to ensure that critical components, critical technology items, essential materials , and...plant mass that is not part of human diet and is not cultivated or is a byproduct of cultivated (for example forest woody biomass , corn stover...security. The United States Navy has taken the lead in this charge by proposing the Defense Production Act (DPA) Title III Biofuel Initiative to

  13. Rocky Flats CAAS System Recalibrated, Retested, and Analyzed to Install in the Criticality Experiments Facility at the Nevada Test Site

    SciTech Connect

    Kim, S; Heinrichs, D; Biswas, D; Huang, S; Dulik, G; Scorby, J; Boussoufi, M; Liu, B; Wilson, R

    2009-05-27

    Neutron detectors and control panels transferred from the Rocky Flats Plant (RFP) were recalibrated and retested for redeployment to the CEF. Testing and calibration were successful with no failure to any equipment. Detector sensitivity was tested at a TRIGA reactor, and the response to thermal neutron flux was satisfactory. MCNP calculated minimum fission yield ({approx} 2 x 10{sup 15} fissions) was applied to determine the thermal flux at selected detector positions at the CEF. Thermal flux levels were greater than 6.39 x 10{sup 6} (n/cm{sup 2}-sec), which was about four orders of magnitude greater than the minimum alarm flux. Calculations of detector survivable distances indicate that, to be out of lethal area, a detector needs to be placed greater than 15 ft away from a maximum credible source. MCNP calculated flux/dose results were independently verified by COG. CAAS calibration and the testing confirmed that the RFP CAAS system is performing its functions as expected. New criteria for the CAAS detector placement and 12-rad zone boundaries at the CEF are established. All of the CAAS related documents and hardware have been transferred from LLNL to NSTec for installation at the CEF high bay areas.

  14. An IR Study of Benzoyl Chloride Adsorbed on KA, NaA, and CaA Zeolites

    NASA Astrophysics Data System (ADS)

    Bardakçı, B.; Bahçeli, Semiha

    2005-09-01

    Infrared spectroscopy has been used to investigate the adsorption of liquid benzoyl chloride on A-type zeolites. The data show that at room temperature the Fermi resonance phenomenon occurs in the adsorption on KA, NaA and CaA zeolites which are little acidic aluminosilicates.

  15. 40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification...

  16. A modular Human Exposure Model (HEM) framework to characterize near-field chemical exposure in LCIA and CAA

    EPA Science Inventory

    Life Cycle Impact Analysis (LCIA) has proven to be a valuable tool for systematically comparing processes and products, and has been proposed for use in Chemical Alternatives Analysis (CAA). The exposure assessment portion of the human health impact scores of LCIA has historicall...

  17. Amine-Appended Hierarchical Ca-A Zeolite for Enhancing CO2 /CH4 Selectivity of Mixed-Matrix Membranes.

    PubMed

    Nguyen, Tien Hoa; Gong, Heqing; Lee, Siew Siang; Bae, Tae-Hyun

    2016-10-18

    An amine-appended hierarchical Ca-A zeolite that can selectively capture CO2 was synthesized and incorporated into inexpensive membrane polymers, in particular polyethylene oxide and Matrimid, to design mixed-matrix membranes with high CO2 /CH4 selectivities. Binary mixture permeation testing reveals that amine-appended mesoporous Ca-A is highly effective in improving CO2 /CH4 selectivity of polymeric membranes. In particular, the CO2 /CH4 selectivity of the polyethylene oxide membrane increases from 15 to 23 by incorporating 20 wt % amine-appended Ca-A zeolite. Furthermore, the formation of filler/polymer interfacial defects, which is typically found in glassy polymer-zeolite pairs, is inhibited owing to the interaction between the amine groups on the external surface of zeolites and polymer chains. Our results suggest that the amine-appended hierarchial Ca-A, which was utilized in membrane fabrication for the first time, is a good filler material for fabricating a CO2 -selective mixed-matrix membrane with defect-free morphology.

  18. 40 CFR 62.14480 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... an operating permit under title V of the Clean Air Act and implementing regulations? 62.14480 Section... the Clean Air Act and implementing regulations? This subpart requires you to obtain an operating permit under title V of the Clean Air Act and implementing regulations (“title V permit”) unless you...

  19. 40 CFR 62.14480 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act and...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... an operating permit under title V of the Clean Air Act and implementing regulations? 62.14480 Section... the Clean Air Act and implementing regulations? This subpart requires you to obtain an operating permit under title V of the Clean Air Act and implementing regulations (“title V permit”) unless you...

  20. 40 CFR 62.14480 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act and...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... an operating permit under title V of the Clean Air Act and implementing regulations? 62.14480 Section... the Clean Air Act and implementing regulations? This subpart requires you to obtain an operating permit under title V of the Clean Air Act and implementing regulations (“title V permit”) unless you...

  1. 40 CFR 62.14480 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act and...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... an operating permit under title V of the Clean Air Act and implementing regulations? 62.14480 Section... the Clean Air Act and implementing regulations? This subpart requires you to obtain an operating permit under title V of the Clean Air Act and implementing regulations (“title V permit”) unless you...

  2. 40 CFR 62.14480 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act and...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... an operating permit under title V of the Clean Air Act and implementing regulations? 62.14480 Section... the Clean Air Act and implementing regulations? This subpart requires you to obtain an operating permit under title V of the Clean Air Act and implementing regulations (“title V permit”) unless you...

  3. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.). 801.6 Section 801.6 Parks... National Environmental Policy Act (42 U.S.C. 4321 et seq.). The National Historic Preservation Act and...

  4. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.). 801.6 Section 801.6 Parks... National Environmental Policy Act (42 U.S.C. 4321 et seq.). The National Historic Preservation Act and...

  5. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.). 801.6 Section 801.6 Parks... National Environmental Policy Act (42 U.S.C. 4321 et seq.). The National Historic Preservation Act and...

  6. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.). 801.6 Section 801.6 Parks, Forests... Environmental Policy Act (42 U.S.C. 4321 et seq.). The National Historic Preservation Act and the...

  7. 36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.). 801.6 Section 801.6 Parks... National Environmental Policy Act (42 U.S.C. 4321 et seq.). The National Historic Preservation Act and...

  8. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an... having a loudspeaker and a radiotelephone auto alarm must be used to keep the continuous watch on 2182...

  9. 78 FR 4725 - Escrow Requirements Under the Truth in Lending Act (Regulation Z)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... requirement for small creditors that operate predominately in rural or underserved areas. Specifically, to be... disclosure would have been required to be given three business days before consummation of a mortgage... business days before consummation or cancellation of the existing escrow account, as applicable....

  10. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and... the bridge-to-bridge frequency and a VTS frequency. (c) Each vessel of the United States...

  11. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  12. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  13. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  14. 48 CFR 52.225-24 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements....225-24 Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act...: Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American...

  15. 48 CFR 52.225-24 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements....225-24 Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act...: Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American...

  16. 48 CFR 52.225-24 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements....225-24 Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act...: Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American...

  17. 48 CFR 52.225-24 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements....225-24 Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act...: Notice of Required Use of American Iron, Steel, and Manufactured Goods—Buy American...

  18. Health promotion research and practice require sound policy analysis models: the case of Quebec's Tobacco Act.

    PubMed

    Breton, Eric; Richard, Lucie; Gagnon, France; Jacques, Marie; Bergeron, Pierre

    2008-12-01

    In this paper we illustrate how policy analysis models can deepen our understanding of the challenges facing health promoters advocating for policy change. Specifically we describe the factors underpinning the adoption of Québec's Tobacco Act (1998) and the role played by actors from governmental public health agencies (GPHAs). Data were collected through interviews (n=39), newspapers articles (n=569) and documents (n > 200) from GPHAs, NGOs, the Québec National Assembly, and opponents to the legislative measures. Data collection and analysis were based on Sabatier and Jenkins-Smith's Advocacy Coalition Framework (1999) and Lemieux's theorization of coalition structuring (1998). We explain the adoption of the Act by: (1) the broad recognition within the policy elite of the main parameters of tobacco use (i.e. lethality, addictive properties, and legitimacy of governmental intervention), (2) the impacts of a series of events (e.g. cigarette contraband crisis) that enabled tobacco control advocates to influence public debates, and the governmental agenda, (3) the critical contribution of a coalition of GPHAs pooling resources to address both the sanitary and economic aspects of the legislation while countering the opposition's strategy, and (4) the failure of the opponents to present an unified voice on the definition of the tobacco policy. This study illustrates the merits of applying a policy-change model to grasp the complexity of the process. Our findings call for the development of permanent policy analysis capabilities within public health agencies and for a broader scrutiny of the non-health-related dimensions of policy debates.

  19. 77 FR 18266 - Notice of Lodging of Consent Decree Under the Resource Conservation and Recovery Act and Clean...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... of Lodging of Consent Decree Under the Resource Conservation and Recovery Act and Clean Air Act... compliance with the Resource Conservation and Recovery Act (``RCRA'') and the Clean Air Act (``CAA''). The... be addressed to the Assistant Attorney General, Environment and Natural Resources Division,...

  20. 75 FR 74048 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA'' or the ``Act''), 42 U.S.C. 7413(g), notice is... CONTACT: Winifred Okoye, Air and Radiation Law Office (2344A), Office of General Counsel,...

  1. 75 FR 75672 - Proposed Settlement Agreement, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-06

    ... AGENCY Proposed Settlement Agreement, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency... accordance with section 113(g) of the Clean Air Act, as amended (``CAA'' or the ``Act''), 42 U.S.C. 7413(g... amended complaint alleging that EPA failed to perform nondiscretionary duties under the Clean Air...

  2. 77 FR 41186 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-12

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... Clean Air Act, as amended ``CAA'' or the ``Act'', notice is hereby given of a proposed consent decree to... above. FOR FURTHER INFORMATION CONTACT: Stephanie L. Hogan, Air and Radiation Law Office (2344A),...

  3. 76 FR 75545 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA'' or the ``Act''), 42 U.S.C. 7413(g), notice is... above. FOR FURTHER INFORMATION CONTACT: Jan Tierney, Air and Radiation Law Office (2344A), Office...

  4. 75 FR 22786 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA'' or the ``Act''), 42 U.S.C. 7413(g), notice is... be mailed to the mailing address above. FOR FURTHER INFORMATION CONTACT: Amy Branning, Air...

  5. 77 FR 4320 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... Valley Unified Air Pollution Control District (the ``District''), and that EPA found complete on December... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA'' or the ``Act''), 42 U.S.C. 7413(g), notice...

  6. A novel cis-acting element required for DNA damage-inducible expression of yeast DIN7

    SciTech Connect

    Yoshitani, Ayako; Yoshida, Minoru; Ling Feng

    2008-01-04

    Din7 is a DNA damage-inducible mitochondrial nuclease that modulates the stability of mitochondrial DNA (mtDNA) in Saccharomyces cerevisiae. How DIN7 gene expression is regulated, however, has remained largely unclear. Using promoter sequence alignment, we found a highly conserved 19-bp sequence in the promoter regions of DIN7 and NTG1, which encodes an oxidative stress-inducible base-excision-repair enzyme. Deletion of the 19-bp sequence markedly reduced the hydroxyurea (HU)-enhanced DIN7 promoter activity. In addition, nuclear fractions prepared from HU-treated cells were used in in vitro band shift assays to reveal the presence of currently unidentified trans-acting factor(s) that preferentially bound to the 19-bp region. These results suggest that the 19-bp sequence is a novel cis-acting element that is required for the regulation of DIN7 expression in response to HU-induced DNA damage.

  7. Early Warning Report: Use of Contractors to Conduct Clean Air Act Risk Management Program Inspections in Certain States Goes Against Court Decisions

    EPA Pesticide Factsheets

    Report #12-P-0376, March 28, 2012. The OIG is currently evaluating whether the EPA has adequate management controls for ensuring the effectiveness of its Clean Air Act (CAA) Section 112(r) risk management program inspections.

  8. 48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... offers. The offeror shall include the information and applicable supporting data required by paragraphs... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  9. 48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... offers. The offeror shall include the information and applicable supporting data required by paragraphs... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  10. 48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... offers. The offeror shall include the information and applicable supporting data required by paragraphs... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  11. 75 FR 44893 - Pipeline Posting Requirements Under Section 23 of the Natural Gas Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ....\\48\\ If, however, the obligation to update previously posted data goes beyond supplying missing data... regulations requiring major non-interstate pipelines to post daily scheduled volume information and other data... Deadline for Future Major Non-Interstate 33 Pipelines D. Confidentiality of Data to be Posted by Major...

  12. 61 FR 31668 - Accidental Release Prevention Requirements: Risk Management Programs Under Clean Air Act Section...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-06-20

    ... compliance with the prevention requirements under OSHA's Process Safety Management Standard. Processes that... history of accidental releases and processes already complying with OSHA's Process Safety Management... applies to all processes subject to the OSHA Process Safety Management (PSM) standard (29 CFR...

  13. Electron transfer dynamics of Rhodothermus marinus caa3 cytochrome c domains on biomimetic films.

    PubMed

    Molinas, Maria F; De Candia, Ariel; Szajnman, Sergio H; Rodríguez, Juan B; Martí, Marcelo; Pereira, Manuela; Teixeira, Miguel; Todorovic, Smilja; Murgida, Daniel H

    2011-10-28

    The subunit II of the caa(3) oxygen reductase from Rhodothermus marinus contains, in addition to the Cu(A) center, a c-type heme group in the cytochrome c domain (Cyt-D) that is the putative primary electron acceptor of the enzyme. In this work we have combined surface-enhanced resonance Raman (SERR) spectroelectrochemistry, molecular dynamics (MD) simulations and electron pathway calculations to assess the most likely interaction domains and electron entry/exit points of the truncated Cyt-D of subunit II in the reactions with its electron donor, HiPIP and electron acceptor, Cu(A). The results indicate that the transient interaction between Cyt-D and HiPIP relies upon a delicate balance of hydrophobic and polar contacts for establishing an optimized electron transfer pathway that involves the exposed edge of the heme group and guaranties efficient inter-protein electron transfer on the nanosecond time scale. The reorganization energy of ca. 0.7 eV was determined by time-resolved SERR spectroelectrochemistry. The intramolecular electron transfer pathway in integral subunit II from Cyt-D to the Cu(A) redox center most likely involves the iron ligand histidine 20 as an electron exit point in Cyt-D.

  14. Guidance On Enforcement of PSD Requirements Under the Clean Air Act

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. Requirement to Publish All Significant Final Actions Under Title I of The Clean Air Act

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Impacts & Compliance Implementation Plans & Required Deviations for Toxic Substance Control Act (TSCA) Regulation of Double Shell Tanks (DST)

    SciTech Connect

    MULKEY, C.H.

    2000-08-22

    In May 2000, the U.S. Department of Energy, Office of River Protection (DOE-ORP) and the U.S. Environmental Protection Agency (EPA) held meetings regarding the management of polychlorinated biphenyls (PCBs) in the Hanford tank waste. It was decided that the radioactive waste currently stored in the double-shell tanks (DSTs) contain waste which will become subject to the Toxic Substance Control Act (TSCA) (40 CFR 761). As a result, DOE-ORP directed the River Protection Project tank farm contractor (TFC) to prepare plans for managing the PCB inventory in the DSTs. Two components of the PCB management plans are this assessment of the operational impacts of TSCA regulation and the identifications of deviations from TSCA that are required to accommodate tank farm unique limitations. This plan provides ORP and CH2M HILL Hanford Group, Inc. (CHG) with an outline of TSCA PCB requirements and their applicability to tank farm activities, and recommends a compliance/implementation approach. Where strict compliance is not possible, the need for deviations from TSCA PCB requirements is identified. The purpose of assembling this information is to enhance the understanding of PCB management requirements, identify operational impacts and select impact mitigation strategies. This information should be useful in developing formal agreements with EPA where required.

  17. 49 CFR Appendix A to Part 228 - Requirements of the Hours of Service Act: Statement of Agency Policy and Interpretation

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... event than an “unavoidable accident or Act of God” under section 5(d) of the Act. Example: The crew of a... of his duties as a trainman. Casualties, Unavoidable Accidents, Acts of God. Section 5(d) of the Act... accident or the Act of God; nor where the delay was the result of a cause not known to the carrier or...

  18. 49 CFR Appendix A to Part 228 - Requirements of the Hours of Service Act: Statement of Agency Policy and Interpretation

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... event than an “unavoidable accident or Act of God” under section 5(d) of the Act. Example: The crew of a... of his duties as a trainman. Casualties, Unavoidable Accidents, Acts of God. Section 5(d) of the Act... accident or the Act of God; nor where the delay was the result of a cause not known to the carrier or...

  19. Ninety-day waiting period limitation and technical amendments to certain health coverage requirements under the Affordable Care Act. Final rule.

    PubMed

    2014-02-24

    These final regulations implement the 90-day waiting period limitation under section 2708 of the Public Health Service Act, as added by the Patient Protection and Affordable Care Act (Affordable Care Act), as amended, and incorporated into the Employee Retirement Income Security Act of 1974 and the Internal Revenue Code. These regulations also finalize amendments to existing regulations to conform to Affordable Care Act provisions. Specifically, these rules amend regulations implementing existing provisions such as some of the portability provisions added by the Health Insurance Portability and Accountability Act of 1996 (HIPAA) because those provisions of the HIPAA regulations have become superseded or require amendment as a result of the market reform protections added by the Affordable Care Act.

  20. Safe Drinking Water Act (SDWA) Resources and FAQs ...

    EPA Pesticide Factsheets

    ECHO, Enforcement and Compliance History Online, provides compliance and enforcement information for approximately 800,000 EPA-regulated facilities nationwide. ECHO includes permit, inspection, violation, enforcement action, and penalty information about facilities regulated under the Clean Air Act (CAA) Stationary Source Program, Clean Water Act (CWA) National Pollutant Elimination Discharge System (NPDES), and/or Resource Conservation and Recovery Act (RCRA). Information also is provided on surrounding demographics when available.

  1. EPA, California Notify Volkswagen of Additional Clean Air Act Violations

    EPA Pesticide Factsheets

    WASHINGTON - Today, EPA is issuing a second notice of violation (NOV) of the Clean Air Act (CAA) to Volkswagen AG, Audi AG and Volkswagen Group of America, Inc. This NOV is also being issued to Porsche AG and Porsche Cars North America. These five c

  2. 40 CFR 62.15395 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... an operating permit under title V of the Clean Air Act? 62.15395 Section 62.15395 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... require me to obtain an operating permit under title V of the Clean Air Act? Yes. If you are subject...

  3. 40 CFR 62.15395 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... an operating permit under title V of the Clean Air Act? 62.15395 Section 62.15395 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... require me to obtain an operating permit under title V of the Clean Air Act? Yes. If you are subject...

  4. 40 CFR 62.15395 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... an operating permit under title V of the Clean Air Act? 62.15395 Section 62.15395 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... require me to obtain an operating permit under title V of the Clean Air Act? Yes. If you are subject...

  5. 40 CFR 62.15395 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... an operating permit under title V of the Clean Air Act? 62.15395 Section 62.15395 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... require me to obtain an operating permit under title V of the Clean Air Act? Yes. If you are subject...

  6. 40 CFR 62.15395 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... an operating permit under title V of the Clean Air Act? 62.15395 Section 62.15395 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... require me to obtain an operating permit under title V of the Clean Air Act? Yes. If you are subject...

  7. The Education Requirement of the U.S. Immigration Reform and Control Act of 1986: A Case Study of Ineffective Language Planning.

    ERIC Educational Resources Information Center

    Huss, Susan

    An analysis of the Immigration Reform and Control Act of 1986 (IRCA), which requires basic English language proficiency and knowledge of United States history and civics of illegal aliens seeking permanent residency status, suggests that the Act is an example of poor language planning. The analysis has three components. First, the legalization…

  8. 45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Ethics in Government Act except: (i) Doctors, dentists and allied medical specialists performing services... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare DEPARTMENT... Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in...

  9. 45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Ethics in Government Act except: (i) Doctors, dentists and allied medical specialists performing services... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare DEPARTMENT... Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in...

  10. 45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Ethics in Government Act except: (i) Doctors, dentists and allied medical specialists performing services... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare DEPARTMENT... Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in...

  11. 45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Ethics in Government Act except: (i) Doctors, dentists and allied medical specialists performing services... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare Department... Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in...

  12. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M. ); Hemenway, A. )

    1991-01-01

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  13. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M.; Hemenway, A.

    1991-12-31

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  14. The cellulose synthase 3 (CesA3) gene of oomycetes: structure, phylogeny and influence on sensitivity to carboxylic acid amide (CAA) fungicides.

    PubMed

    Blum, Mathias; Gamper, Hannes A; Waldner, Maya; Sierotzki, Helge; Gisi, Ulrich

    2012-04-01

    Proper disease control is very important to minimize yield losses caused by oomycetes in many crops. Today, oomycete control is partially achieved by breeding for resistance, but mainly by application of single-site mode of action fungicides including the carboxylic acid amides (CAAs). Despite having mostly specific targets, fungicidal activity can differ even in species belonging to the same phylum but the underlying mechanisms are often poorly understood. In an attempt to elucidate the phylogenetic basis and underlying molecular mechanism of sensitivity and tolerance to CAAs, the cellulose synthase 3 (CesA3) gene was isolated and characterized, encoding the target site of this fungicide class. The CesA3 gene was present in all 25 species included in this study representing the orders Albuginales, Leptomitales, Peronosporales, Pythiales, Rhipidiales and Saprolegniales, and based on phylogenetic analyses, enabled good resolution of all the different taxonomic orders. Sensitivity assays using the CAA fungicide mandipropamid (MPD) demonstrated that only species belonging to the Peronosporales were inhibited by the fungicide. Molecular data provided evidence, that the observed difference in sensitivity to CAAs between Peronosporales and CAA tolerant species is most likely caused by an inherent amino acid configuration at position 1109 in CesA3 possibly affecting fungicide binding. The present study not only succeeded in linking CAA sensitivity of various oomycetes to the inherent CesA3 target site configuration, but could also relate it to the broader phylogenetic context.

  15. 76 FR 66285 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ...-fired boiler; (IV) CAA section 112(j) for air toxics; and (V) PSD ] requirements in regard to carbon dioxide (CO 2 ) emissions. On September 29, 2011, the Administrator issued an Administrative Order...

  16. 75 FR 39014 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA''), 42 U.S.C. 7413(g), notice is hereby given of a... mailing address above. FOR FURTHER INFORMATION CONTACT: Mark Kataoka, Air and Radiation Law Office...

  17. 77 FR 46757 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA''), notice is hereby given of a proposed consent... INFORMATION CONTACT: David Orlin, Air and Radiation Law Office (2344A), Office of General Counsel,...

  18. 77 FR 65684 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA''), notice is hereby given of a proposed consent... Amended Complaint alleging that EPA failed to perform nondiscretionary duties under the Clean Air...

  19. 78 FR 26028 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA''), notice is hereby given of a proposed consent... Dakota, and Utah with regard to the 2006 PM 2.5 National Ambient Air Quality Standard (``NAAQS'')....

  20. 75 FR 54873 - Proposed Settlement Agreement, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed Settlement Agreement, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency... accordance with section 113(g) of the Clean Air Act, as amended (``CAA''), 42 U.S.C. 7413(g), notice...

  1. 77 FR 66978 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Proposed Consent Decree, Clean Air Act Citizen Suit AGENCY: Environmental Protection Agency (EPA... section 113(g) of the Clean Air Act, as amended (``CAA''), notice is hereby given of a proposed...

  2. 40 CFR 62.14830 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... an operating permit under title V of the Clean Air Act? 62.14830 Section 62.14830 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... Requirements § 62.14830 Does this subpart require me to obtain an operating permit under title V of the...

  3. 40 CFR 62.14830 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... an operating permit under title V of the Clean Air Act? 62.14830 Section 62.14830 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... Requirements § 62.14830 Does this subpart require me to obtain an operating permit under title V of the...

  4. 40 CFR 62.14830 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... an operating permit under title V of the Clean Air Act? 62.14830 Section 62.14830 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... Requirements § 62.14830 Does this subpart require me to obtain an operating permit under title V of the...

  5. 40 CFR 62.14830 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... an operating permit under title V of the Clean Air Act? 62.14830 Section 62.14830 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... Requirements § 62.14830 Does this subpart require me to obtain an operating permit under title V of the...

  6. 40 CFR 62.14830 - Does this subpart require me to obtain an operating permit under title V of the Clean Air Act?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... an operating permit under title V of the Clean Air Act? 62.14830 Section 62.14830 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF... Requirements § 62.14830 Does this subpart require me to obtain an operating permit under title V of the...

  7. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... destination, you must use the U.S. flag air carrier service unless such use would extend your travel time... the U.S. by 2 or more; or (2) Extend your travel time by at least 6 hours or more; or (3) Require a... Fly America Act requirements apply when I travel between the United States and another country?...

  8. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... or more; or (b) Extend your travel time by 6 hours or more; or (c) Require a connecting time of 4... Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL...

  9. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... or more; or (b) Extend your travel time by 6 hours or more; or (c) Require a connecting time of 4... Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL...

  10. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... destination, you must use the U.S. flag air carrier service unless such use would extend your travel time... the U.S. by 2 or more; or (2) Extend your travel time by at least 6 hours or more; or (3) Require a... Fly America Act requirements apply when I travel between the United States and another country?...

  11. No Child Left Behind Act: Improved Accessibility to Education's Information Could Help States Further Implement Teacher Qualification Requirements. Report to Congressional Requesters. GAO-06-25

    ERIC Educational Resources Information Center

    Shaul, Marnie S.

    2005-01-01

    This GAO report examines response of 47 states to the No Child Left Behind Act (NCLBA) of 2001 that established qualification requirements for teachers of core academic subjects that must meet by the end of the 2005-2006 school year. With the deadline approaching for all teachers to meet the requirements, GAO was asked to examine the following:…

  12. 48 CFR 52.225-22 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-22 Section 52... Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following provision: Notice of Required Use of American Iron, Steel,...

  13. 48 CFR 52.225-22 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-22 Section 52... Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following provision: Notice of Required Use of American Iron, Steel,...

  14. 48 CFR 52.225-22 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-22 Section 52... Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following provision: Notice of Required Use of American Iron, Steel,...

  15. 48 CFR 52.225-22 - Notice of Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... American Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-22 Section 52... Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following provision: Notice of Required Use of American Iron, Steel,...

  16. [Justification of repeated animal experiments and determination of the required number of animals according to the German Animal Protection Act].

    PubMed

    Schneider, Berthold

    2009-01-01

    The repetition of animal experiments requires justification according to the German Animal Protection Act (Tierschutzgesetz). On the other hand, repetition of experiments is considered necessary for the improvement of the precision and reliability of the results. In this paper it is shown that such improvement is not achieved by a repetition of the experiment but by repeated inclusion of animals into the experiment. The more animals are included, the more precisely and reliably the results can be generalized to further situations. The number of animals necessary for a proposed precision can be determined with statistical methods. The basic ideas are explained in the paper and demonstrated with two examples. In long term experiments the precision can be improved, if all experimental conditions are applied within temporally homogenous blocks to few animals and the blocks are repeated till the necessary number of animals is reached (block experiments). By sequential interim analyses, where at each analysis on the basis of all available data a decision on continuation or conclusion of the experiment is drawn, a further reduction of the number of animals can be achieved. These methods are discussed in the paper. Repetitions of total animal experiments are justified, if there exist legitimate doubts on the soundness of the published results or if in so called ring-experiments the variability of the results between different laboratories should be investigated.

  17. BACT analysis under the Clean Air Act's PCD program

    SciTech Connect

    Simms, P.; Walke, J.

    2006-11-15

    Before a company may build a new major industrial source of air pollution, or make modifications to an existing major source in the USA it must apply for and receive a Clean Air Act (CAA) Prevention of Significant Deterioration (PSD) permit. State environmental agencies typically issue such permits, either under state law or by exercising delegated authority to implement the federal PSD program. To fully comply with the CAA, the emissions limits identified as BACT must incorporate consideration of more than just add-on emissions control technology, they must also reflect appropriate considerations of fuel quality (e.g. low-sulfur coal) and process changes (e.g. advanced combustion techniques) as a means of controlling emissions, and must consider the other environmental and public welfare benefits of the identified emissions control options. Several states including New Mexico and Illinois have already determined that innovated technologies, such as Integrated Gasification Combined Cycle (IGCC), must be considered in connection with the BACT analysis for new coal-fired power plants. Even the notion that BACT is categorically limited in scope to the general type of facility proposed is contrary to EPA precedent. For example, the Environmental Appeals Board (EAB) has explained that permitting authorities retain the discretion under the definition of BACT to require dramatically different facility designs (e.g. a natural gas plant instead of a coal-fired power plant). The best advice for any permit applicant is to include in the BACT analysis a careful and honest examination of better performing alternative processes and/or innovative combustion techniques and to aggressively pursue such options wherever feasible. 17 refs.

  18. A Standard Analysis Method (SAM) for the automated analysis of polychlorinated biphenyls (PCBs) in soils using the chemical analysis automation (CAA) paradigm: Validation and performance

    SciTech Connect

    Rzeszutko, C.; Johnson, C.R.; Monagle, M.; Klatt, L.N.

    1997-11-01

    The Chemical Analysis Automation (CAA) program is developing a standardized modular automation strategy for chemical analysis. In this automation concept, analytical chemistry is performed with modular building blocks that correspond to individual elements of the steps in the analytical process. With a standardized set of behaviors and interactions, these blocks can be assembled in a plug-and-play manner into a complete analysis system. These building blocks, which are referred to as Standard laboratory Modules (SLM), interface to a host control system that orchestrates the entire analytical process, from sample preparation through data interpretation. The integrated system is called a Standard Analysis Method (SAM). A SAM for the automated determination of polychlorinated biphenyls (PCBs) in soils, assembled in a mobile laboratory, is undergoing extensive testing and validation. The SAM consists of the following SLMs: a four-channel Soxhlet extractor, a high-volume concentration, a column clean-up, a gas chromatography, a PCB data-interpretation module, a robot, and a human-computer interface. The SAM is configured to meet the requirements specified in the US Environmental Protection Agency`s (EPA) SW-846 methods 3541/3620A/8082 for the analysis of PCBs in soils. The PCB SAM will be described along with the developmental test plan. Performance data obtained during developmental testing will also be discussed.

  19. A standard analysis method (SAM) for the automated analysis of polychlorinated biphenyls (PCBs) in soils using the chemical analysis automation (CAA) paradigm: validation and performance

    SciTech Connect

    Rzeszutko, C.; Johnson, C.R.; Monagle, M.; Klatt, L.N.

    1997-10-01

    The Chemical Analysis Automation (CAA) program is developing a standardized modular automation strategy for chemical analysis. In this automation concept, analytical chemistry is performed with modular building blocks that correspond to individual elements of the steps in the analytical process. With a standardized set of behaviors and interactions, these blocks can be assembled in a `plug and play` manner into a complete analysis system. These building blocks, which are referred to as Standard Laboratory Modules (SLM), interface to a host control system that orchestrates the entire analytical process, from sample preparation through data interpretation. The integrated system is called a Standard Analysis Method (SAME). A SAME for the automated determination of Polychlorinated Biphenyls (PCB) in soils, assembled in a mobile laboratory, is undergoing extensive testing and validation. The SAME consists of the following SLMs: a four channel Soxhlet extractor, a High Volume Concentrator, column clean up, a gas chromatograph, a PCB data interpretation module, a robot, and a human- computer interface. The SAME is configured to meet the requirements specified in U.S. Environmental Protection Agency`s (EPA) SW-846 Methods 3541/3620A/8082 for the analysis of pcbs in soils. The PCB SAME will be described along with the developmental test plan. Performance data obtained during developmental testing will also be discussed.

  20. Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

    NASA Technical Reports Server (NTRS)

    Liever, Peter A.; West, Jeffrey S.

    2016-01-01

    A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

  1. Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

    NASA Technical Reports Server (NTRS)

    Liever, Peter A.; West, Jeffrey S.; Harris, Robert E.

    2016-01-01

    A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate Discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured mesh Discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

  2. 40 CFR 52.353 - Section 110(a)(2) infrastructure requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... provides the state of Colorado's SIP provisions for meeting the requirements of CAA Section 110(a)(1) and (2) relevant to the 1997 8-hour ozone NAAQS. The State's 1997 Ozone Infrastructure SIP is...

  3. 40 CFR 52.353 - Section 110(a)(2) infrastructure requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... provides the state of Colorado's SIP provisions for meeting the requirements of CAA Section 110(a)(1) and (2) relevant to the 1997 8-hour ozone NAAQS. The State's 1997 Ozone Infrastructure SIP is...

  4. 49 CFR Appendix A to Part 228 - Requirements of the Hours of Service Act: Statement of Agency Policy and Interpretation

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: Statement of Agency Policy and Interpretation A Appendix A to Part 228 Transportation Other Regulations... Service Act: Statement of Agency Policy and Interpretation First enacted in 1907, the Hours of Service Act... or operation of trains. Employees who perform this type of service commonly include...

  5. ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle

    PubMed Central

    1994-01-01

    As part of our ongoing efforts to understand the functional role of vertebrate centractins, we have identified a new member of the actin- related family of proteins in the yeast Saccharomyces cerevisiae using a PCR-based approach. Consistent with the current nomenclature for actin-related proteins in yeast, we propose to denote this locus ACT3. The primary amino acid sequence of Act3p is most similar to canine and human alpha-centractin (73% similarity/54% identity). The sequence of a genomic clone indicates ACT3 lies adjacent to and is transcribed convergently with respect to FUR1 on chromosome VIII. Molecular genetic analysis indicates ACT3 is represented by a single gene from which the corresponding mRNA is expressed at a low level compared to ACT1. Tetrad analysis of heterozygotes harboring a TRP1 replacement of the ACT3- coding region indicates ACT3 is nonessential for growth under normal conditions and at extremes of temperature and osmolarity. However, growth at 14 degrees C indicates a spindle orientation defect similar to phenotypes recently described for yeast harboring mutations in actin, tubulin, or cytoplasmic dynein. Taken together, our data suggest that ACT3 is the S. cerevisiae homologue of vertebrate centractins. PMID:7929558

  6. Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism.

    PubMed Central

    Singer, J D; Manning, B M; Formosa, T

    1996-01-01

    We have developed a genetic screen of the yeast Saccharomyces cerevisiae to identify genes that act to coordinate DNA replication so that each part of the genome is copied exactly once per cell cycle. A mutant was recovered in this screen that accumulates aberrantly high DNA contents but does not complete a second round of synthesis. The mutation principally responsible for this phenotype is in the DOA4 gene, which encodes a ubiquitin hydrolase, one of several yeast genes that encode enzymes that can remove the signalling polypeptide ubiquitin hydrolase, one of several yeast genes that encode enzymes that can remove the signaling polypeptide ubiquitin from its covalently linked conjugated forms. DOA4 is nonessential, and deleting this gene causes uncoordinated replication. Overreplication does not occur in cells with limiting amounts of Cdc7 protein kinase, suggesting that entry into S phase is required for this phenotype. The DNA formed in doa4 mutants is not highly unusual in the sense that mitotic recombination rates are normal, implying that a high level of repair is not induced. The temperature sensitivity of doa4 mutations is partially suppressed by extra copies of the polyubiquitin gene UB14, but overreplication still occurs in the presence of this suppressor. Mutations in DOA4 cause loss of the free ubiquitin pool in cells under heat stress conditions, and extra copies of UB14 restore this pool without restoring coordination of replication. We conclude that a ubiquitin-mediated signaling event directly involving the ubiquitin hydrolase encoded by DOA4 is needed in S. cerevisiae to prevent uncoordinated DNA replication. PMID:8657109

  7. 20 CFR 652.209 - What are the requirements under the Act for providing reemployment services and other activities...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FUNCTIONING OF STATE EMPLOYMENT SERVICES Wagner-Peyser Act Services in a One-Stop Delivery System Environment... part of the One-Stop delivery system, must provide reemployment services to UI claimants for whom...

  8. 24 CFR 1000.42 - Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable? 1000.42 Section 1000.42 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF...

  9. 24 CFR 1000.42 - Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable? 1000.42 Section 1000.42 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF...

  10. 24 CFR 1000.42 - Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable? 1000.42 Section 1000.42 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF...

  11. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  12. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  13. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  14. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family...

  15. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family...

  16. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family...

  17. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family...

  18. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family...

  19. The Education Requirement of the U.S. Immigration Reform and Control Act of 1986: A Case Study of Ineffective Language Planning.

    ERIC Educational Resources Information Center

    Huss, Susan

    1990-01-01

    Under the 1986 Immigration Reform Act, illegal aliens could fulfill English, history, and civics knowledge requirements by attending instructional programs. Because the goal was to grant these aliens residency before foreign nationals applying under other programs, not to help individuals achieve English competency, the language policy has been…

  20. 48 CFR 52.225-21 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-21 Section 52.225... of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following clause: Required Use of American Iron, Steel, and...

  1. 48 CFR 52.225-23 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements. 52....225-23 Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction... American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials Under Trade...

  2. 48 CFR 52.225-23 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements. 52....225-23 Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction... American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials Under Trade...

  3. 48 CFR 52.225-21 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-21 Section 52.225... of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following clause: Required Use of American Iron, Steel, and...

  4. 48 CFR 52.225-23 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements. 52....225-23 Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction... American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials Under Trade...

  5. 48 CFR 52.225-21 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-21 Section 52.225... of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following clause: Required Use of American Iron, Steel, and...

  6. 48 CFR 52.225-21 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials. 52.225-21 Section 52.225... of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials. As prescribed in 25.1102(e), insert the following clause: Required Use of American Iron, Steel, and...

  7. 48 CFR 52.225-23 - Required Use of American Iron, Steel, and Manufactured Goods-Buy American Act-Construction...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Iron, Steel, and Manufactured Goods-Buy American Act-Construction Materials Under Trade Agreements. 52....225-23 Required Use of American Iron, Steel, and Manufactured Goods—Buy American Act—Construction... American Iron, Steel, and Manufactured Goods—Buy American Act—Construction Materials Under Trade...

  8. Standard Compliance: Guidelines to Help State and Alternative Fuel Provider Fleets Meet Their Energy Policy Act Requirements, 10 CFR Part 490 (Book)

    SciTech Connect

    Not Available

    2012-04-01

    This guidebook addresses the primary requirements of the Alternative Fuel Transportation Program to help state and alternative fuel provider fleets comply with the Energy Policy Act via the Standard Compliance option. It also addresses the topics that covered fleets ask about most frequently.

  9. Standard Compliance: Guidelines to Help State and Alternative Fuel Provider Fleets Meet Their Energy Policy Act Requirements, 10 CFR Part 490 (Book)

    SciTech Connect

    Not Available

    2014-03-01

    This guidebook addresses the primary requirements of the Alternative Fuel Transportation Program to help state and alternative fuel provider fleets comply with the Energy Policy Act via the Standard Compliance option. It also addresses the topics that covered fleets ask about most frequently.

  10. 24 CFR 1000.42 - Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable? 1000.42 Section 1000.42 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF...

  11. 45 CFR 73.735-902 - Reporting requirements for certain employees not covered by the Ethics in Government Act of 1978.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... covered by the Ethics in Government Act of 1978. 73.735-902 Section 73.735-902 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION STANDARDS OF CONDUCT Reporting Financial Interests § 73.735-902 Reporting requirements for certain employees not covered by the Ethics in...

  12. Early detection of circulating anodic antigen (CAA) in a case of acute schistosomiasis mansoni with Katayama fever.

    PubMed

    Gundersen, S G; Ravn, J; Haagensen, I

    1992-01-01

    A 34-year-old male developed acute Katayama fever with fever, diarrhoea, joint pains, headache, urticarial rash and eosinophilia 18 days after falling into and spending 15 min in the water during water-skiing in the outlet of the Volta river. Low anti-schistosomal antibody titres were found by the immunofluorescence assay after 4 weeks, and the first Schistosoma mansoni eggs were found in faeces after 6 weeks. Both symptoms and eosinophilia increased the first days after treatment with oxamniquine, after which he improved gradually. Examination of frozen sera by the newly developed Magnetic Beads Antigen Capture-EIA (MBAC-EIA) later demonstrated a peak in schistosomal circulating anodic antigen (CAA) levels of diagnostic significance already 4 weeks after he was infected.

  13. Changes to EPCRA, CERCLA, CAA 112(r) Consolidated List of Lists – March 2015

    EPA Pesticide Factsheets

    Changes include adding to the explanation for applying TPQs for EHS that are molten solids or solids in solution, reinstated TRI reporting requirements for hydrogen sulfide, and updated radionuclides list.

  14. RCRA special study on waste definitions: Sites that require additional consideration prior to NPL proposal under the Superfund Amendments and Reauthorization Act. Directive

    SciTech Connect

    Not Available

    1987-03-10

    The purposes of this memo are to discuss Sections 105(g) and 125 of the Superfund Amendments and Reauthorization Act of 1986 (SARA) and, to the extent now possible, to outline the scope of these provisions by providing appropriate definitions. Both of these sections require that, until the Hazard Ranking System (HRS) is revised, the Agency evaluate additional data for sites at which 'special wastes,' as defined under the Resource Conservation and Recovery Act (RCRA), are present in significant quantities before these sites are proposed for the NPL.

  15. 75 FR 27580 - Notice of Lodging of Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... proposed Consent Decree (``Decree'') in United States v. The Pep Boys--Manny, Moe & Jack, and Baja, Inc.... EPA''), sought penalties and injunctive relief under the Clean Air Act (``CAA'') against The Pep Boys... of Justice, Washington, DC 20044-7611, and should refer to United States v. The Pep Boys--Manny,...

  16. 76 FR 22918 - Notice of Lodging of Consent Decree Pursuant to the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... and injunctive relief for violations of the Clean Air Act (``CAA'') by Terra Industries Inc. (``Terra... States and State Co-Plaintiffs a civil penalty of $625,000 and implement injunctive relief at all nine of... District of Iowa, Hach Building Suite 400, 401 First St. SE, Cedar Rapids, IA 52401-1825. The...

  17. 12 CFR 1026.36 - Prohibited acts or practices and certain requirements for credit secured by a dwelling.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., 12 U.S.C. 5102 et seq.), its implementing regulations (12 CFR part 1007 or part 1008), and State SAFE... System, as applicable) pursuant to section 19 of the Federal Deposit Insurance Act (FDIA), 12 U.S.C. 1829...), 12 U.S.C. 1785(d), or the Farm Credit Administration pursuant to section 5.65(d) of the Farm...

  18. 49 CFR Appendix A to Part 228 - Requirements of the Hours of Service Act: Statement of Agency Policy and Interpretation

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF SERVICE OF RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Pt. 228, App. A... excess service could not have been avoided. Sleeping Quarters. Under the 1976 amendments to the Act it is unlawful for any common carrier to provide sleeping quarters for persons covered by the Hours of...

  19. 15 CFR 744.11 - License requirements that apply to entities acting contrary to the national security or foreign...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... entities acting contrary to the national security or foreign policy interests of the United States. 744.11... national security or foreign policy interests of the United States. BIS may impose foreign policy export... of being or becoming involved in activities that are contrary to the national security or...

  20. 15 CFR 744.11 - License requirements that apply to entities acting contrary to the national security or foreign...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... entities acting contrary to the national security or foreign policy interests of the United States. 744.11... national security or foreign policy interests of the United States. BIS may impose foreign policy export... of being or becoming involved in activities that are contrary to the national security or...

  1. 2 CFR 176.190 - Award term-Wage rate requirements under Section 1606 of the Recovery Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the Davis-Bacon and related Acts. Regulations in 29 CFR 5.5 instruct agencies concerning application of the standard Davis-Bacon contract clauses set forth in that section. Federal agencies providing...-Bacon contract clauses found in 29 CFR 5.5(a) are incorporated in any resultant covered contracts...

  2. 2 CFR 176.190 - Award term-Wage rate requirements under Section 1606 of the Recovery Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the Davis-Bacon and related Acts. Regulations in 29 CFR 5.5 instruct agencies concerning application of the standard Davis-Bacon contract clauses set forth in that section. Federal agencies providing...-Bacon contract clauses found in 29 CFR 5.5(a) are incorporated in any resultant covered contracts...

  3. 2 CFR 176.190 - Award term-Wage rate requirements under Section 1606 of the Recovery Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Davis-Bacon and related Acts. Regulations in 29 CFR 5.5 instruct agencies concerning application of the standard Davis-Bacon contract clauses set forth in that section. Federal agencies providing...-Bacon contract clauses found in 29 CFR 5.5(a) are incorporated in any resultant covered contracts...

  4. Cross-talk between Aβ and endothelial SSAO/VAP-1 accelerates vascular damage and Aβ aggregation related to CAA-AD.

    PubMed

    Solé, Montse; Miñano-Molina, Alfredo J; Unzeta, Mercedes

    2015-02-01

    An association between semicarbazide-sensitive amine oxidase (SSAO) and cerebral amyloid angiopathy (CAA) related to Alzheimer's disease (AD) has been largely postulated. Increased SSAO activity and expression have been detected in cerebrovascular tissue and plasma of AD patients, colocalizing with cerebrovascular amyloid-beta (Aβ) deposits. As an enzyme, SSAO metabolizes primary amines generating hydrogen peroxide, ammonia, and aldehydes. The ability of these products to generate oxidative stress, to enhance the advanced glycation end-product generation, to promote the Aβ aggregation in vitro, and to induce apoptosis supports its role in CAA-related vascular pathology. However, whether the SSAO increase constitutes a cause or it is a consequence of the pathologic process has not been elucidated so far. To set up the nature of this relationship, vascular cell models expressing SSAO were treated with different Aβ forms, simulating the CAA conditions in vitro. It was found that the presence of the vasculotropic Dutch-mutated Aβ1-40 increases (Aβ1-40 D) the SSAO-dependent toxicity, which is accompanied by an increase of SSAO protein availability in endothelial cell membranes. In addition, SSAO enhances Aβ1-40 D and Aβ1-42 deposition on vascular cells by both activity-dependent and -independent mechanisms. Thus, we provide evidences indicating that Aβ itself could be one of the factors inducing SSAO increase in AD, enhancing its toxic effect, and inducing the vascular dysfunction and, in turn, that SSAO stimulates Aβ deposition on the vascular walls, thereby contributing to the CAA-AD progression. Therefore, molecules inhibiting SSAO could provide an alternative treatment for preventing/delaying the progress of CAA-AD-associated vasculopathy.

  5. 15 CFR 744.11 - License requirements that apply to entities acting contrary to the national security or foreign...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., and set license application review policy based on the criteria in this section. Such requirements... that entry in addition to any other applicable review policy stated elsewhere in the EAR. (b) Criteria... party to be listed and the failure to produce a complete, accurate and useful check is required,...

  6. 15 CFR Supplement No. 1 to Part 730 - Information Collection Requirements Under the Paperwork Reduction Act: OMB Control Numbers

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Information Collection Requirements... requirements for the Bureau of Industry and Security by the Office of Management and Budget (OMB), pursuant...

  7. 15 CFR Supplement No. 1 to Part 730 - Information Collection Requirements Under the Paperwork Reduction Act: OMB Control Numbers

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND... 15 Commerce and Foreign Trade 2 2012-01-01 2012-01-01 false Information Collection Requirements... requirements for the Bureau of Industry and Security by the Office of Management and Budget (OMB), pursuant...

  8. 15 CFR Supplement No. 1 to Part 730 - Information Collection Requirements Under the Paperwork Reduction Act: OMB Control Numbers

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Information Collection Requirements... requirements for the Bureau of Industry and Security by the Office of Management and Budget (OMB), pursuant...

  9. ICASE/LaRC Workshop on Benchmark Problems in Computational Aeroacoustics (CAA)

    NASA Technical Reports Server (NTRS)

    Hardin, Jay C. (Editor); Ristorcelli, J. Ray (Editor); Tam, Christopher K. W. (Editor)

    1995-01-01

    The proceedings of the Benchmark Problems in Computational Aeroacoustics Workshop held at NASA Langley Research Center are the subject of this report. The purpose of the Workshop was to assess the utility of a number of numerical schemes in the context of the unusual requirements of aeroacoustical calculations. The schemes were assessed from the viewpoint of dispersion and dissipation -- issues important to long time integration and long distance propagation in aeroacoustics. Also investigated were the effect of implementation of different boundary conditions. The Workshop included a forum in which practical engineering problems related to computational aeroacoustics were discussed. This discussion took the form of a dialogue between an industrial panel and the workshop participants and was an effort to suggest the direction of evolution of this field in the context of current engineering needs.

  10. Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene.

    PubMed Central

    Li, Y; Shen, R F; Tsai, S Y; Woo, S L

    1988-01-01

    The human alpha-1-antitrypsin (AAT) gene is expressed in the liver, and its deficiency causes pulmonary emphysema. We have demonstrated that its 5'-flanking region contains cis-acting elements capable of directing proper transcription in the presence of rat liver nuclear extract. The in vitro transcription system is tissue-specific in that the AAT promoter is functional in nuclear extracts prepared from the liver but not from HeLa cells. Experiments in which rat liver and HeLa nuclear extracts were mixed suggested the presence of a specific activator(s) in hepatocytes rather than a repressor(s) in nonproducing cells. Two protected regions were detected in the promoter by DNase I footprinting analysis with rat liver nuclear extracts. Region one spanned -78 to -52 and region two spanned -125 to -100 in the 5'-flanking sequence of the gene. By gel retardation assays with synthetic oligonucleotides, at least two distinct liver nuclear factors were identified, HNF-1 and HNF-2 (hepatocyte nuclear factors), which bound specifically to the first and second region, respectively. We present evidence that HNF-1 and HNF-2 are positively acting, tissue-specific transcription factors that regulate hepatic expression of the human AAT gene. Images PMID:3263567

  11. North Carolina's Implementation of Visibility Impact Assessment Requirements for New Major Stationary Sources and Major Modifications Subject to Clean Air Act Prevention of Significant Deterioration Requirements

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  12. National School Lunch Program and School Breakfast Program: Eliminating Applications Through Community Eligibility as Required by the Healthy, Hunger-Free Kids Act of 2010. Final rule.

    PubMed

    2016-07-29

    This final rule establishes requirements for State agencies, local educational agencies, and schools operating the Community Eligibility Provision, a reimbursement option that allows the service of school meals to all children at no-cost in high poverty schools without collecting household applications. By eliminating the household application process and streamlining meal counting and claiming procedures through the Community Eligibility Provision, local educational agencies may substantially reduce administrative burden related to operating the National School Lunch and School Breakfast Programs. This rule codifies many requirements that were implemented through policy guidance following enactment of the Healthy, Hunger-Free Kids Act of 2010, as well as provisions of the proposed rule. These requirements will result in consistent, national implementation of the Community Eligibility Provision.

  13. Direct Loan System Requirements: Checklist for Reviewing Systems under the Federal Financial Management Improvement Act. Financial Management Series.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Accounting and Information Management Div.

    This checklist reflects the requirements of the revised Direct Loan System of the Joint Financial Management Improvement Program to assist agencies in implementing and monitoring their direct loan system and to help managers and auditors review their direct loan systems to determine if they comply with the Federal Financial Management Improvement…

  14. 76 FR 76874 - Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... packers, swine contractors and live poultry dealers to retain records justifying differential pricing... ``justify'' a price differential in such a case. Agency Response: The final regulations will require no such... suggested the exact date of re-delivery following suspension may be impossible to determine. They said...

  15. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  16. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  17. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  18. 18 CFR Appendix A to Part 380 - Minimum Filing Requirements for Environmental Reports Under the Natural Gas Act

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...)). 6. Describe construction and restoration methods. (§ 380.12(c)(6)). 7. Identify the permits required for construction across surface waters. (§ 380.12(c)(9)). 8. Provide the names and address of all...). (§§ 380.12(c)(10)) Resource Report 2—Water Use and Quality 1. Identify all perennial surface...

  19. 18 CFR Appendix A to Part 380 - Minimum Filing Requirements for Environmental Reports Under the Natural Gas Act

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...)). 6. Describe construction and restoration methods. (§ 380.12(c)(6)). 7. Identify the permits required for construction across surface waters. (§ 380.12(c)(9)). 8. Provide the names and address of all...). (§§ 380.12(c)(10)) Resource Report 2—Water Use and Quality 1. Identify all perennial surface...

  20. 18 CFR Appendix A to Part 380 - Minimum Filing Requirements for Environmental Reports Under the Natural Gas Act

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...)). 6. Describe construction and restoration methods. (§ 380.12(c)(6)). 7. Identify the permits required for construction across surface waters. (§ 380.12(c)(9)). 8. Provide the names and address of all...). (§§ 380.12(c)(10)) Resource Report 2—Water Use and Quality 1. Identify all perennial surface...

  1. 15 CFR 744.11 - License requirements that apply to entities acting contrary to the national security or foreign...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... section by adding an entity to the Entity List (Supp. No. 4 to this part) with a reference to this section and by stating on the Entity List the license requirements and license application review policy that apply to that entity. BIS may remove an entity from the Entity List if it is no longer engaged in...

  2. Regulated expression of mammalian histone H4 genes in vivo requires a trans-acting transcription factor.

    PubMed Central

    Capasso, O; Heintz, N

    1985-01-01

    Mouse L cells containing integrated copies of a human histone H4 gene have been obtained by cotransfection with the herpesvirus thymidine kinase gene. Nuclease S1 assays of RNA from several independent cell lines show that the expression of the introduced H4 gene is regulated during the cell cycle. One of these cell lines (line 6-8) contains more than 60 human H4 gene copies per haploid genome and does not express the endogenous mouse histone H4 mRNA. In contrast, the expression of the mouse H2a and H3 mRNAs in this cell line is not perturbed. In cell revertants that have lost the majority of the human H4 gene copies, the expression of the mouse H4 mRNA is restored, demonstrating that the mouse genes remain functional although not expressed. The rate of transcription of the histone H4 genes in clone 6-8 is at least 10-fold greater than that of the parental cell line and it is regulated during traversal of the cell cycle. These results show that the expression of mammalian histone H4 genes involves both a trans-acting transcriptional regulatory factor and an H4-specific activity. We propose that cell cycle regulation of histone gene expression may be effected through subtype-specific transcriptional regulatory proteins. Images PMID:3862085

  3. Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression

    SciTech Connect

    Wek, R.C.; Ramirez, M.; Jackson, B.M.; Hinnebusch, A.G. )

    1990-06-01

    GCN4 is a transcriptional activator of amino acid-biosynthetic genes in the yeast {ital Saccharomyces cerevisiae}. GCN2, a translational activator of {ital GCN4} expression, contains a domain homologous to the catalytic subunit of eukaryotic protein kinases. Substitution of a highly conserved lysine residue in the kinase domain abolished GCN2 regulatory function in vivo and its ability to autophosphorylate in vitro, indicating that GCN2 acts as a protein kinase in stimulating {ital GCN4} expression. Elevated {ital GCN2} gene dosage led to depression of {ital GCN4} under nonstarvation conditions; however, the authors found that {ital GCN2} mRNA and protein levels did not increase in wild-type cells in response to amino acid starvation. Therefore, it appears that GCN2 protein kinase function is stimulated postranslationally in amino acid-starved cells. Three dominant-constitutive {ital GCN2} point mutations were isolated that led to derepressed {ital GCN4} expression under nonstarvation conditions. Two of the {ital GCN2}(Con) mutations mapped in the kinase domain itself. The third mapped just downstream from a carboxyl-terminal segment homologous to histidyl-tRNA synthetase (HisRS), which the authors suggest might function to detect uncharged tRNA in amino acid-starved cells and activate the adjacent protein kinase moiety.

  4. The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription

    PubMed Central

    Bonnet, Jacques; Wang, Chen-Yi; Baptista, Tiago; Vincent, Stéphane D.; Hsiao, Wei-Chun; Stierle, Matthieu; Kao, Cheng-Fu; Tora, László

    2014-01-01

    The SAGA (Spt–Ada–Gcn5 acetyltransferase) coactivator complex contains distinct chromatin-modifying activities and is recruited by DNA-bound activators to regulate the expression of a subset of genes. Surprisingly, recent studies revealed little overlap between genome-wide SAGA-binding profiles and changes in gene expression upon depletion of subunits of the complex. As indicators of SAGA recruitment on chromatin, we monitored in yeast and human cells the genome-wide distribution of histone H3K9 acetylation and H2B ubiquitination, which are respectively deposited or removed by SAGA. Changes in these modifications after inactivation of the corresponding enzyme revealed that SAGA acetylates the promoters and deubiquitinates the transcribed region of all expressed genes. In agreement with this broad distribution, we show that SAGA plays a critical role for RNA polymerase II recruitment at all expressed genes. In addition, through quantification of newly synthesized RNA, we demonstrated that SAGA inactivation induced a strong decrease of mRNA synthesis at all tested genes. Analysis of the SAGA deubiquitination activity further revealed that SAGA acts on the whole transcribed genome in a very fast manner, indicating a highly dynamic association of the complex with chromatin. Thus, our study uncovers a new function for SAGA as a bone fide cofactor for all RNA polymerase II transcription. PMID:25228644

  5. Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae.

    PubMed Central

    Trueblood, C E; Ohya, Y; Rine, J

    1993-01-01

    Two protein prenyltransferase enzymes, farnesyltransferase (FTase) and geranylgeranyltransferase-I (GGTase-I), catalyze the covalent attachment of a farnesyl or geranylgeranyl lipid group to the cysteine of a CaaX sequence (cysteine [C], two aliphatic amino acids [aa], and any amino acid [X]. In vitro studies reported here confirm previous reports that CaaX proteins with a C-terminal serine are farnesylated by FTase and those with a C-terminal leucine are geranylgeranylated by GGTase-I. In addition, we found that FTase can farnesylate CaaX proteins with a C-terminal leucine and can transfer a geranylgeranyl group to some CaaX proteins. Genetic data indicate that FTase and GGTase-I have the same substrate preferences in vivo as in vitro and also show that each enzyme can prenylate some of the preferred substrates of the other enzyme in vivo. Specifically, the viability of yeast cells lacking FTase is due to prenylation of Ras proteins by GGTase-I. Although this GGTase-I dependent prenylation of Ras is sufficient for growth, it is not sufficient for mutationally activated Ras proteins to exert deleterious effects on growth. The dependence of the activated Ras phenotype on FTase can be bypassed by replacing the C-terminal serine with leucine. This altered form of Ras appears to be prenylated by both GGTase-I and FTase, since it produces an activated phenotype in a strain lacking either FTase or GGTase-I. Yeast cells can grow in the absence of GGTase-I as long as two essential substrates are overexpressed, but their growth is slow. Such strains are dependent on FTase for viability and are able to grow faster when FTase is overproduced, suggesting that FTase can prenylate the essential substrates of GGTase-I when they are overproduced. Images PMID:8321228

  6. 78 FR 13645 - Notice of Public Meetings for the Draft Environmental Impact Statement and Draft Clean Air Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... Air Act General Conformity Determination for U.S. Navy F-35C West Coast Homebasing AGENCY: Department...) General Conformity Regulations (40 CFR part 93, subpart B), the DoN has prepared a Draft CAA General Conformity Determination, which is included in the Draft EIS, to address air emission impacts associated...

  7. 75 FR 22400 - Clean Air Act Operating Permit Program; Petition To Object to Title V Permit for Wheelabrator...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Baltimore, L.P., Baltimore City, MD AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of final action. SUMMARY: Pursuant to section 505(b)(2) of the Clean Air Act (CAA), the EPA Administrator signed... Wheelabrator Baltimore, L.P. for its facility located in Baltimore City, Maryland. This order constitutes...

  8. Qualification Requirement Perceptions of the United States Army Acquisition Workforce Since Implementation of the Defense Acquisition Workforce Improvement Act (DAWIA)

    DTIC Science & Technology

    2013-12-01

    much like a self-licking ice cream cone. Certification requirements are changed way too often with seemingly no valid reason to do so. The...Although asked in the survey, this survey seems to support a DAU self-licking ice cream cone theme. DAU is ok; not great. A lot of money is poured...Sciences 0 Mathemat ics 0 Psychology 0 Educat ion 0 Health 0 V isual & Performing Arts 0 Communications & Journalism 0 Language & Literature 0

  9. Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding.

    PubMed

    Nishimura, Akiyuki; Linder, Maurine E

    2013-04-01

    Membrane localization of Rho GTPases is essential for their biological functions and is dictated in part by a series of posttranslational modifications at a carboxyl-terminal CaaX motif: prenylation at cysteine, proteolysis of the aaX tripeptide, and carboxymethylation. The fidelity and variability of these CaaX processing steps are uncertain. The brain-specific splice variant of Cdc42 (bCdc42) terminates in a CCIF sequence. Here we show that brain Cdc42 undergoes two different types of posttranslational modification: classical CaaX processing or novel tandem prenylation and palmitoylation at the CCaX cysteines. In the dual lipidation pathway, bCdc42 was prenylated, but it bypassed proteolysis and carboxymethylation to undergo modification with palmitate at the second cysteine. The alternative postprenylation processing fates were conserved in the GTPases RalA and RalB and the phosphatase PRL-3, proteins terminating in a CCaX motif. The differentially modified forms of bCdc42 displayed functional differences. Prenylated and palmitoylated brain Cdc42 did not interact with RhoGDIα and was enriched in the plasma membrane relative to the classically processed form. The alternative processing of prenylated CCaX motif proteins by palmitoylation or by endoproteolysis and methylation expands the diversity of signaling GTPases and enables another level of regulation through reversible modification with palmitate.

  10. Isolation of ubiquinol oxidase from Paracoccus denitrificans and resolution into cytochrome bc1 and cytochrome c-aa3 complexes.

    PubMed

    Berry, E A; Trumpower, B L

    1985-02-25

    An enzyme complex with ubiquinol-cytochrome c oxidoreductase, cytochrome c oxidase, and ubiquinol oxidase activities was purified from a detergent extract of the plasma membrane of aerobically grown Paracoccus denitrificans. This ubiquinol oxidase consists of seven polypeptides and contains two b cytochromes, cytochrome c1, cytochrome aa3, and a previously unreported c-type cytochrome. This c-type cytochrome has an apparent Mr of 22,000 and an alpha absorption maximum at 552 nm. Retention of this c cytochrome through purification presumably accounts for the independence of ubiquinol oxidase activity on added cytochrome c. Ubiquinol oxidase can be separated into a 3-subunit bc1 complex, a 3-subunit c-aa3 complex, and a 57-kDa polypeptide. This, together with detection of covalently bound heme and published molecular weights of cytochrome c1 and the subunits of cytochrome c oxidase, allows tentative identification of most of the subunits of ubiquinol oxidase with the prosthetic groups present. Ubiquinol oxidase contains cytochromes corresponding to those of the mitochondrial bc1 complex, cytochrome c oxidase complex, and a bound cytochrome c. Ubiquinol-cytochrome c oxidoreductase activity of the complex is inhibited by inhibitors of the mitochondrial bc1 complex. Thus it seems likely that the pathway of electron transfer through the bc1 complex of ubiquinol oxidase is similar to that through the mitochondrial bc1 complex. The number of polypeptides present is less than half the number in the corresponding mitochondrial complexes. This structural simplicity may make ubiquinol oxidase from P. denitrificans a useful system with which to study the mechanisms of electron transfer and energy transduction in the bc1 and cytochrome c oxidase sections of the respiratory chain.

  11. Raffinose Family Oligosaccharides Act As Galactose Stores in Seeds and Are Required for Rapid Germination of Arabidopsis in the Dark

    PubMed Central

    Gangl, Roman; Tenhaken, Raimund

    2016-01-01

    Raffinose synthase 5 (AtRS5, At5g40390) was characterized from Arabidopsis as a recombinant enzyme. It has a far higher affinity for the substrates galactinol and sucrose than any other raffinose synthase previously reported. In addition raffinose synthase 5 is also working as a galactosylhydrolase, degrading galactinol, and raffinose under certain conditions. Together with raffinose synthase 4, which is predominantly a stachyose synthase, both enzymes contribute to the raffinose family oligosaccharide (RFO) accumulation in seeds. A double knockout in raffinose synthase 4 and raffinose synthase 5 (ΔAtRS4,5) was generated, which is devoid of RFOs in seeds. Unstressed leaves of 4 week old ΔAtRS4,5 plants showed drastically 23.8-fold increased concentrations of galactinol. Unexpectedly, raffinose appeared again in drought stressed ΔAtRS4,5 plants, but not under other abiotic stress conditions. Drought stress leads to novel transcripts of raffinose synthase 6 suggesting that this isoform is a further stress inducible raffinose synthase in Arabidopsis. ΔAtRS4,5 seeds showed a 5 days delayed germination phenotype in darkness and an elevated expression of the transcription factor phytochrome interacting factor 1 (AtPIF1) target gene AtPIF6, being a repressor of germination. This prolonged dormancy is not seen during germination in the light. Exogenous galactose partially promotes germination of ΔAtRS4,5 seeds in the dark suggesting that RFOs act as a galactose store and repress AtPIF6 transcripts. PMID:27507985

  12. Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; policies, requirements, and administrative procedures; delay of effective date. Final rule; delay of effective date.

    PubMed

    2004-02-23

    The Food and Drug Administration (FDA) is further delaying, until December 1, 2006, the effective date of certain requirements of a final rule published in the Federal Register of December 3, 1999 (64 FR 67720). In the Federal Register of May 3, 2000 (65 FR 25639), the agency delayed until October 1, 2001, the effective date of certain requirements in the final rule relating to wholesale distribution of prescription drugs by distributors that are not authorized distributors of record, and distribution of blood derivatives by entities that meet the definition of a "health care entity" in the final rule. The agency further delayed the effective date of these requirements in three subsequent Federal Register notices. Most recently, in the Federal Register of January 31, 2003 (68 FR 4912), FDA delayed the effective date until April 1, 2004. This action further delays the effective date of these requirements until December 1, 2006. The final rule implements the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA), and the Food and Drug Administration Modernization Act of 1997 (the Modernization Act). The agency is taking this action to address concerns about the requirements in the final rule raised by affected parties. As explained in the SUPPLEMENTARY INFORMATION section, FDA is working with stakeholders through its counterfeit drug initiative to facilitate widespread, voluntary adoption of track and trace technologies that will generate a de facto electronic pedigree, including prior transaction history back to the original manufacturer, as a routine course of business. If this technology is widely adopted, it is expected to help fulfill the pedigree requirements of the PDMA and obviate or resolve many of the concerns that have been raised with respect to the final rule by ensuring that an electronic pedigree travels with a drug product at all times. Therefore, it is necessary to delay the effective date of Sec

  13. Policy Decisions With Regard To The Applicability Of The Clean Air Act Requirements To The Strategic Petroleum Reserve

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. CAA: Computer Assisted Athletics.

    ERIC Educational Resources Information Center

    Hall, John H.

    Computers have been used in a variety of applications for athletics since the late 1950's. These have ranged from computer-controlled electric scoreboards to computer-designed pole vaulting poles. Described in this paper are a computer-based athletic injury reporting system and a computer-assisted football scouting system. The injury reporting…

  15. cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

    PubMed Central

    Thompson, C B; Wang, C Y; Ho, I C; Bohjanen, P R; Petryniak, B; June, C H; Miesfeldt, S; Zhang, L; Nabel, G J; Karpinski, B

    1992-01-01

    The recent definition of a consensus DNA binding sequence for the Ets family of transcription factors has allowed the identification of potential Ets binding sites in the promoters and enhancers of many inducible T-cell genes. In the studies described in this report, we have identified two potential Ets binding sites, EBS1 and EBS2, which are conserved in both the human and murine interleukin-2 enhancers. Within the human enhancer, these two sites are located within the previously defined DNase I footprints, NFAT-1 and NFIL-2B, respectively. Electrophoretic mobility shift and methylation interference analyses demonstrated that EBS1 and EBS2 are essential for the formation of the NFAT-1 and NFIL-2B nuclear protein complexes. Furthermore, in vitro mutagenesis experiments demonstrated that inducible interleukin-2 enhancer function requires the presence of either EBS1 or EBS2. Two well-characterized Ets family members, Ets-1 and Ets-2, are reciprocally expressed during T-cell activation. Surprisingly, however, neither of these proteins bound in vitro to EBS1 or EBS2. We therefore screened a T-cell cDNA library under low-stringency conditions with a probe from the DNA binding domain of Ets-1 and isolated a novel Ets family member, Elf-1. Elf-1 contains a DNA binding domain that is nearly identical to that of E74, the ecdysone-inducible Drosophila transcription factor required for metamorphosis (hence the name Elf-1, for E74-like factor 1). Elf-1 bound specifically to both EBS1 and EBS2 in electrophoretic mobility shift assays. It also bound to the purine-rich CD3R element from the human immunodeficiency virus type 2 long terminal repeat, which is required for inducible virus expression in response to signalling through the T-cell receptor. Taken together, these results demonstrate that multiple Ets family members with apparently distinct DNA binding specificities regulate differential gene expression in resting and activated T cells. Images PMID:1545787

  16. The Implications of ACTS Technology on the Requirements of Rain Attenuation Modeling for Communication System Specification and Analysis at 30/20 GHz and Beyond

    NASA Technical Reports Server (NTRS)

    Manning, Robert M.

    1996-01-01

    The advent of the use of the Ka-Band for space communications, coupled with the introduction of digital modulation techniques as well as multiple-beam methodology for satellites, has deemed it necessary to reassess the plethora of rain attenuation prediction models in use. The Advanced Communication Technology Satellite (ACTS) Project, undertaken by the National Aeronautics and Space Administration in 1983, offered such challenges to rain attenuation prediction modeling. Up to 1983, no such single modeling formalism existed that could fill such requirements. Not even the work done by the NASA Propagation Experimenters (NAPEX) Group had envisioned such requirements, so no dynamic Ka-Band data existed from which one could draw conclusions. In this paper, the basic rudiments of what has become to be known as the 'ACTS Rain Attenuation Prediction Model' will be presented. The concept of rain fade mitigation control availability will be introduced. A new evaluation is then presented for the performance of satellite communication systems, in particular, those to be operating within the Ka-Band and above, that will necessarily employ some type of dynamic rain fade mitigation procedure.

  17. Final Requirements--School Improvement Grants--Title I of the Elementary and Secondary Education Act of 1965. Final Rule. Federal Register, Part IV, Department of Education, 34 CFR Chapter II

    ERIC Educational Resources Information Center

    National Archives and Records Administration, 2015

    2015-01-01

    The Assistant Secretary for Elementary and Secondary Education adopts final requirements for the School Improvement Grants (SIG) program, authorized under section 1003(g) of title I of the Elementary and Secondary Education Act of 1965, as amended (ESEA). These final requirements make changes to the current SIG program requirements and implement…

  18. 75 FR 78267 - Notice of Lodging of Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ..., a proposed Consent Decree in United States of America and the Commonwealth of Kentucky v. Logan... V permit provisions of the CAA, 42 U.S.C. 7661a(a), occurring at Logan Aluminum's Russellville, Kentucky secondary aluminum facility. The proposed Consent Decree requires Logan Aluminum to perform...

  19. cis-acting DNA regulatory elements, including the retinoic acid response element, are required for tissue specific laminin B1 promoter/lacZ expression in transgenic mice.

    PubMed

    Sharif, K A; Li, C; Gudas, L J

    2001-05-01

    The LAMB1 gene encodes the laminin beta1 subunit of laminin, an extracellular matrix protein. Using several transgenic mouse lines containing various lengths of the LAMB1 promoter driving lacZ reporter gene expression, regions of LAMB1 promoter that contain cis-acting DNA regulatory element(s) have been identified. The 3.9LAMB1betagal transgene is expressed in various tissues during development. LAMB1 transgene expression is observed in a selective set of nephrons of the neonatal and adult kidneys. The cis-acting DNA regulatory elements responsible for LAMB1 transgene expression in ovaries and in juvenile kidneys are present between -'1.4 and -0.7 kb relative to the transcription start site, while those of adult kidneys are located between -2.5 and -1.4 kb. The LAMB1 transgene is also expressed in the epididymis of 1 week old transgenic mice. Mutation of the retinoic acid response element (RARE) in the context of the 3.9LAMB1betagal transgene results in loss of LAMB1 transgene expression in all tissues. Thus, sequences between -2.5 and -0.7 kb plus the RARE are required for appropriate expression of the LAMB1 transgene in mice.

  20. 78 FR 55993 - Revisions to Reporting and Recordkeeping Requirements, and Proposed Confidentiality...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... facilities. 325110 Ethylene production facilities. 325182 Carbon black production facilities. Petroleum and... abbreviations are used in this document. BAMM Best Available Monitoring Methods CAA Clean Air Act CO 2 carbon... ton CKD produced). ] P Hydrogen Production Name and annual quantity (metric tons) of each...

  1. Meeting the Tobacco Cessation Coverage Requirement of the Patient Protection and Affordable Care Act: State Smoking Cessation Quitlines and Cost Sharing

    PubMed Central

    Bailey, Linda; Leischow, Scott J.

    2015-01-01

    Objectives. We explored whether various key stakeholders considered cost sharing with state telephone-based tobacco cessation quitlines, because including tobacco cessation services as part of the required essential health benefits is a new requirement of the Patient Protection and Affordable Care Act (ACA). Methods. We analyzed qualitative data collected from interviews conducted in April and May of 2014 with representatives of state health departments, quitline service providers, health plans, and insurance brokers in 4 US states. Results. State health departments varied in the strategies they considered the role their state quitline would play in meeting the ACA requirements. Health plans and insurance brokers referred to state quitlines because they were perceived as effective and free, but in 3 of the 4 states, the private stakeholder groups did not consider cost sharing. Conclusions. If state health departments are going to initiate cost-sharing agreements with private insurance providers, then they will need to engage a broad array of stakeholders and will need to overcome the perception that state quitline services are free. PMID:26447918

  2. The Slicer Activity of ARGONAUTE1 Is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis[OPEN

    PubMed Central

    Marchais, Antonin; Poulsen, Christian; Hauptmann, Judith; Meister, Gunter

    2016-01-01

    ARGONAUTE1 (AGO1) mediates posttranscriptional silencing by microRNAs (miRNAs) and short interfering RNAS (siRNAs). AGO1-catalyzed RNA cleavage (slicing) represses miRNA targets, but current models also highlight the roles of slicing in formation of siRNAs and siRNA-AGO1 complexes. miRNA-guided slicing is required for biogenesis of phased, trans-acting siRNAs (tasiRNAs), whose cleaved precursor fragments are converted to double-stranded RNA by RNA-dependent RNA polymerase 6 (RDR6). In addition, unwinding of duplex siRNA bound to AGO1 requires passenger strand cleavage in vitro. In this study, we analyze how mutation of four metal ion-coordinating residues of Arabidopsis thaliana AGO1 affects slicer activity in vitro and siRNA function in vivo. We show that while all four residues are required for slicer activity, they do not contribute equally to catalysis. Moreover, passenger strand cleavage is required for assembly of active AGO1-siRNA complexes in vivo, and many AGO1-bound siRNAs are trimmed in the absence of slicer activity. Remarkably, seedlings defective in AGO1 slicer activity produce abundant siRNAs from tasiRNA loci in vivo. These siRNAs depend on RDR6 and SUPPRESSOR OF GENE SILENCING3, but unlike wild-type tasiRNAs, they are unphased. These results demonstrate that slicing is solely required for phase definition of tasiRNAs, and they strongly support recruitment of RDR6 by AGO1 rather than by cleavage fragments. PMID:27354557

  3. A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.

    PubMed

    2016-04-01

    The above article from European Journal of Neuroscience, published online on 5 March 2013 in Wiley Online Library (http://onlinelibrary.wiley.com/doi/10.1111/ejn.12162/full), has been retracted by agreement between the Editors-in-Chief, Paul Bolam and John Foxe, the authors and John Wiley & Sons Ltd. The retraction has been agreed as Dr Phillip Barber has informed the publisher that he had seen neither the original data nor any version of the manuscript, and had not been involved in the work reported. A subsequent Institutional investigation found evidence of misconduct on the part of the submitting author. Reference Wang, L.-M., Wang, Y.-J., Cui, M., Luo, W.-J., Wang, X.-J., Barber, P.A. & Chen, Z.-Y. (2013) A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.

  4. Tanker navigation safety standards: Tanker navigation safety research baseline: A study required by section 4111(b)(9) of the Oil Pollution Act of 1990. Final report

    SciTech Connect

    1996-12-31

    The Oil Pollution Act of 1990 directed the Secretary of Transportation to review and incorporate the results of past studies, including studies by the Coast Guard and Office of Technology Assessment (OTA). This literature search and review focuses on materials pertinent to determining or evaluating current and/or `best` practices, and not on the adequacy of current statutes or regulations. In addition, it is not the intention of the report to assess best practices (e.g., suggest the appropriate crew sizes or what navigation equipment should be required on tankers), but to establish the baseline for future study of best practices. The report does not provide answers to new analytical quations, but presents the status of research so that questions addressed previoulsy will not be duplicated by future studies.

  5. Requiring E-VERIFI Act

    THOMAS, 113th Congress

    Sen. Coburn, Tom [R-OK

    2013-08-01

    08/01/2013 Read twice and referred to the Committee on Finance. (All Actions) Notes: For further action, see H.R.2775, which became Public Law 113-46 on 10/17/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. EPA, California Notify Volkswagen of Clean Air Act Violations / Carmaker allegedly used software that circumvents emissions testing for certain air pollutants

    EPA Pesticide Factsheets

    WASHINGTON -- Today, EPA is issuing a notice of violation (NOV) of the Clean Air Act (CAA) to Volkswagen AG, Audi AG, and Volkswagen Group of America, Inc. (collectively referred to as Volkswagen). The NOV alleges that four-cylinder Volkswagen and A

  7. Guidance for federal facilities on release notification requirements under CERCLA and SARA Title 3

    SciTech Connect

    Not Available

    1990-11-01

    The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA or Superfund''), as amended, creates a framework for Federal involvement in response to and cleanup of hazardous substance releases. Although many of its provisions deal with cleanup, liability, and compensation associated with inactive or abandoned hazardous waste sites, equally important parts of CERCLA address the reporting of and response to releases of hazardous substances as they occur. The statute establishes a list of hazardous substances,'' of which there are currently 727. The CERCLA list contains hazardous substances identified under other statutes, including the Clean Water Act (CWS), the Clean Air Act (CAA), and the Resource Conservation and Recovery Act (RCRA). CERCLA also contains a provision authorizing the Administrator of the US Environmental Protection Agency (EPA) to add substances to the list that when released into the environment may present substantial danger to the public health or welfare or the environment...'' EPA is providing this guidance document so that Federal facilities may better understand the CERCLA and SARA Title 3 release notification requirements. The information is presented in a variety of formats, including questions and answers, fact sheets, scenarios, and a flowchart. A glossary of key terms also has been included in this document. 5 figs.

  8. Comparison of the Effects of the US Clean Air Act and of Smoking Prevention and Cessation Efforts on the Risk of Acute Myelogenous Leukemia

    PubMed Central

    Liu, Yan; Wu, Felicia; Lioy, Paul

    2011-01-01

    Objectives. We used 2 approaches based on published information to compare the impacts on leukemia incidence and benzene exposure of the 1990 US Clean Air Act (CAA) amendments and smoking prevention and cessation efforts. Methods. We extrapolated leukemia mortality related to community air pollution levels and to cigarette smoking from data from the US Environmental Protection Agency and the US Surgeon General. We also estimated relative decline in total exposures to benzene (a known human leukemogen) owing to the CAA amendments and to smoking prevention and cessation efforts. Results. We estimated that because of the CAA, there will be approximately 300 fewer leukemia deaths in the United States during the period 2000 through 2020. During the closest comparable period (1987–2007), we estimated that decline in cigarette smoking led to 7120 fewer leukemia deaths, of which 1282 to 3702 were attributable to benzene. Similarly, the decline in smoking led to about a tenfold greater decrease in total-population benzene exposure than did the 1990 CAA amendments. Conclusions. Both the CAA and smoking cessation activities contribute to a decrease in leukemia incidence. Smoking cessation activities have had a greater effect in the past. PMID:22021318

  9. Chromosomal position effects reveal different cis-acting requirements for rDNA transcription and sex chromosome pairing in Drosophila melanogaster.

    PubMed Central

    Briscoe, A; Tomkiel, J E

    2000-01-01

    In Drosophila melanogaster, the rDNA loci function in ribosome biogenesis and nucleolar formation and also as sex chromosome pairing sites in male meiosis. These activities are not dependent on the heterochromatic location of the rDNA, because euchromatic transgenes are competent to form nucleoli and restore pairing to rDNA-deficient X chromosomes. These transgene studies, however, do not address requirements for the function of the endogenous rDNA loci within the heterochromatin. Here we describe two chromosome rearrangements that disrupt rDNA functions. Both rearrangements are translocations that cause an extreme bobbed visible phenotype and XY nondisjunction and meiotic drive in males. However, neither rearrangement interacts with a specific Y chromosome, Ymal(+), that induces male sterility in combination with rDNA deletions. Molecular studies show that the translocations are not associated with gross rearrangements of the rDNA repeat arrays. Rather, suppression of the bobbed phenotypes by Y heterochromatin suggests that decreased rDNA function is caused by a chromosomal position effect. While both translocations affect rDNA transcription, only one disrupts meiotic XY pairing, indicating that there are different cis-acting requirements for rDNA transcription and rDNA-mediated meiotic pairing. PMID:10880481

  10. State of competition in gasoline marketing. The effects of refiner operation at retail (a study required by Title III of the Petroleum Marketing Practices Act)

    SciTech Connect

    Delaney, J.B.; Fenili, R.N.

    1980-05-01

    Title III of the Petroleum Marketing Practices Act requires the Secretary of Energy to report to the Congress on the extent to which producers, refiners, and other suppliers of motor fuel subsidize the sale of such fuel at retail or wholesale with profits obtained from other operations. This is Part I of the report required under that Title. It addresses a number of questions relating to the central issue - the state of competition in the gasoline marketing industry. Part II of the report, to be issued this fall, will discuss the subpoenaed documents of nine integrated companies, and will contain recommendations for action, if deemed necessary. The basic thrust of Part I is an examination of three issues: (1) Are integrated refiners subsidizing their company operated gasoline retail outlets; (2) Are integrated refiners moving gasoline away from their branded dealer network into their own retail outlets; and (3) Are integrated refiners manipulating the allocation system in favor of their own retail outlets to the detriment of other gasoline marketers. At a series of regional hearings, independent marketers charged that integrated refiners were engaging in each of these practices. In essence, integrated refiners were portrayed as using unfair or illegal competitive practices which would ultimately lead to their domination of retail gasoline markets. This report addresses each allegation, after providing a historical and theoretical framework for today's debate.

  11. Simultaneous detection of Hb constant spring (α142, TAA>CAA, α2) and the α2 IVS-I donor site (-TGAGG) deletion by a simple polymerase chain reaction-based method in Iran.

    PubMed

    Akhavan-Niaki, Haleh; Banihashemi, Ali; Mostafazadeh, Amrollah; Kholghi Oskooei, Vahid; Azizi, Mandana; Youssefi Kamangar, Reza; Elmi, Maryam Mitra

    2012-01-01

    Hb Constant Spring (Hb CS, codon 142, TAA>CAA, α2) (HBA2:c.427T>C) and α2 IVS-I donor site (GAGGTGAGG>GAGG - - - - -) (HBA2:c.95+2_95+6delTGAGG) are nondeletional α-thalassemia (α-thal) mutations found all over the world. Identification of α-thal genotypes in at-risk couples for severe anemia or in highly heterogeneous populations requires rapid, accurate and cost-effective genotyping methods. In this study, a pair of primers were used to specifically amplify an 883 bp fragment from the α2-globin gene in order to simultaneously identify these two mutations by a PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) method. We determined the genotypic frequencies of Hb CS and the α2 IVS-I donor site mutations after amplification and enzymatic digestion with Tru9I in 238 northern Iranian samples referred for α-thal testing. Hb CS and the α2 IVS-I donor site mutations accounted for 21 (8.8%) and 29 (12.2%) of the nondeletional cases. This genotyping assay has proven to be a rapid, reliable and useful diagnostic tool for simultaneous detection of these two anomalies for genetic counseling or further prenatal diagnosis.

  12. In vitro- and in vivo-generated defective RNAs of satellite panicum mosaic virus define cis-acting RNA elements required for replication and movement.

    PubMed

    Qiu, W; Scholthof, K B

    2000-03-01

    Satellite panicum mosaic virus (SPMV) depends on its helper virus, panicum mosaic virus (PMV), to provide trans-acting proteins for replication and movement. The 824-nucleotide (nt) genome of SPMV possesses an open reading frame encoding a 17.5-kDa capsid protein (CP), which is shown to be dispensable for SPMV replication. To localize cis-acting RNA elements required for replication and movement, a comprehensive set of SPMV cDNA deletion mutants was generated. The results showed that the 263-nt 3' untranslated region (UTR) plus 73 nt upstream of the CP stop codon and the first 16 nt in the 5' UTR are required for SPMV RNA amplification and/or systemic spread. A region from nt 17 to 67 within the 5' UTR may have an accessory role in RNA accumulation, and a fragment bracketing nt 68 to 104 appears to be involved in the systemic movement of SPMV RNA in a host-dependent manner. Unexpectedly, defective RNAs (D-RNAs) accumulated de novo in millet plants coinfected with PMV and either of two SPMV mutants: SPMV-91, which is incapable of expressing the 17.5-kDa CP, and SPMV-GUG, which expresses low levels of the 17.5-kDa CP. The D-RNA derived from SPMV-91 was isolated from infected plants and used as a template to generate a cDNA clone. RNA transcripts derived from this 399-nt cDNA replicated and moved in millet plants coinoculated with PMV. The characterization of this D-RNA provided a biological confirmation that the critical RNA domains identified by the reverse genetic strategy are essential for SPMV replication and movement. The results additionally suggest that a potential "trigger" for spontaneous D-RNA accumulation may be associated with the absence or reduced accumulation of the 17.5-kDa SPMV CP. This represents the first report of a D-RNA associated with a satellite virus.

  13. Deeming Tobacco Products To Be Subject to the Federal Food, Drug, and Cosmetic Act, as Amended by the Family Smoking Prevention and Tobacco Control Act; Restrictions on the Sale and Distribution of Tobacco Products and Required Warning Statements for Tobacco Products. Final rule.

    PubMed

    2016-05-10

    The Food and Drug Administration (FDA) is issuing this final rule to deem products meeting the statutory definition of "tobacco product,'' except accessories of the newly deemed tobacco products, to be subject to the Federal Food, Drug, and Cosmetic Act (the FD&C Act), as amended by the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act). The Tobacco Control Act provides FDA authority to regulate cigarettes, cigarette tobacco, roll-your-own tobacco, smokeless tobacco, and any other tobacco products that the Agency by regulation deems to be subject to the law. With this final rule, FDA is extending the Agency's "tobacco product'' authorities in the FD&C Act to all other categories of products that meet the statutory definition of "tobacco product" in the FD&C Act, except accessories of such newly deemed tobacco products. This final rule also prohibits the sale of "covered tobacco products" to individuals under the age of 18 and requires the display of health warnings on cigarette tobacco, roll-your own tobacco, and covered tobacco product packages and in advertisements. FDA is taking this action to reduce the death and disease from tobacco products. In accordance with the Tobacco Control Act, we consider and intend the extension of our authorities over tobacco products and the various requirements and prohibitions established by this rule to be severable.

  14. ACT and College Success

    ERIC Educational Resources Information Center

    Bleyaert, Barbara

    2010-01-01

    What is the relationship between ACT scores and success in college? For decades, admissions policies in colleges and universities across the country have required applicants to submit scores from a college entrance exam, most typically the ACT (American College Testing) or SAT (Scholastic Aptitude Test). This requirement suggests that high school…

  15. Cell division genes ftsQAZ in Escherichia coli require distant cis-acting signals upstream of ddlB for full expression.

    PubMed

    Flärdh, K; Palacios, P; Vicente, M

    1998-10-01

    A transcriptional reporter fusion has been introduced into the chromosomal ftsZ locus in such a way that all transcription that normally reaches ftsZ can be monitored. The new Phi(ftsZ-lacZ ) fusion yields four times more beta-galactosidase activity than a ddlB-ftsQAZ-lacZ fusion on a lambda prophage vector. A strongly polar ddlB ::Omega insertion prevents contributions from signals upstream of the ftsQAZ promoters and decreases transcription of the chromosomal Phi(ftsZ-lacZ ) fusion by 66%, demonstrating that around two-thirds of total ftsZ transcription require cis-acting elements upstream of ddlB. We suggest that those elements are distant promoters, and thus that the cell division and cell wall synthesis genes in the dcw gene cluster are to a large extent co-transcribed. The ddlB ::Omega insertion is lethal unless additional copies of ftsQA are provided or a compensatory decrease in FtsZ synthesis is made. This shows that ddlB is a dispensable gene, and reinforces the critical role of the FtsA/FtsZ ratio in septation. Using the new reporter fusion, it is demonstrated that ftsZ expression is not autoregulated.

  16. A particular DNA structure is required for the function of a cis-acting component of the Epstein-Barr virus OriLyt origin of replication.

    PubMed Central

    Portes-Sentis, S; Sergeant, A; Gruffat, H

    1997-01-01

    OriLyt, thecis-acting element of Epstein-Barr virus lytic origin of replication, consists of upstream and downstream components. The upstream component plays a dual role in transcription and replication. The downstream component contains a homopurine-homopyrimidine sequence which forms an H palindrome. We show that the downstream component can adopt a triple helix structure in vitro, that the 5' border of the homopyrimidine sequence is sensitive to P1 nuclease when carried by a supercoiled plasmid and that an oligonucleotide complementary to the homopyrimidine strand is taken up by a plasmid carrying the OriLyt H palindrome. We also show that all mutations which alter the H palindrome impair both oligonucleotide uptake and OriLyt-dependent replication. Interestingly, compensatory mutations which restore an H palindrome also restore oligonucleotide uptake by the mutated plasmids and their OriLyt-dependent replication. Thus, there is a strong correlation between the inability of the OriLyt H palindrome to form a non-B-DNA structure in vitro and impairment of OriLyt-dependent replication. This suggests that the presence of a non-B-DNA structure in the OriLyt downstream component is required for OriLyt-dependent replication. PMID:9060428

  17. RIG-I is required for VSV-induced cytokine production by murine glia and acts in combination with DAI to initiate responses to HSV-1.

    PubMed

    Crill, Emma K; Furr-Rogers, Samantha R; Marriott, Ian

    2015-12-01

    A defining feature of viral central nervous system (CNS) infection is the rapid onset of severe neuroinflammation. However, the mechanisms underlying glial responses to replicative neurotropic viruses are only now becoming apparent with the discovery of a number of cytosolic sensors for viral nucleic acids. We have described the expression by murine and human glial cells of two disparate pattern recognition receptors, retinoic acid inducible gene-I (RIG-I) and DNA-dependent activator of interferon regulatory factors (DAI), receptors for viral RNA and DNA moieties, respectively. In the present study, we demonstrate the functional significance of RIG-I expression in primary murine microglia and astrocytes. Our data indicate that murine glial immune responses to a model neurotropic RNA virus, vesicular stomatitis virus, are RIG-I dependent and independent of levels of DAI expression or RNA polymerase III activity. In contrast, maximal glial inflammatory and antiviral responses to the DNA virus herpes simplex virus-1 (HSV-1) are dependent on the expression of both RIG-I and DAI, and require RNA polymerase III activity. These findings indicate that the RNA sensor, RIG-I, acts in parallel with DAI in an RNA polymerase III-dependent manner to initiate glial responses to HSV-1. We therefore suggest that RIG-I plays a significant role in the detection of both RNA and DNA pathogens by microglia and astrocytes.

  18. cis-acting sequences required for expression of the divergently transcribed Drosophila melanogaster Sgs-7 and Sgs-8 glue protein genes.

    PubMed Central

    Hofmann, A; Garfinkel, M D; Meyerowitz, E M

    1991-01-01

    The Sgs-7 and Sgs-8 glue genes at 68C are divergently transcribed and are separated by 475 bp. Fusion genes with Adh or lacZ coding sequences were constructed, and the expression of these genes, with different amounts of upstream sequences present, was tested by a transient expression procedure and by germ line transformation. A cis-acting element for both genes is located asymmetrically in the intergenic region between -211 and -43 bp relative to Sgs-7. It is required for correct expression of both genes. This element can confer the stage- and tissue-specific expression pattern of glue genes on a heterologous promoter. An 86-bp portion of the element, from -133 to -48 bp relative to Sgs-7, is shown to be capable of enhancing the expression of a truncated and therefore weakly expressed Sgs-3 fusion gene. Recently described common sequence motifs of glue gene regulatory elements (T. Todo, M. Roark, K. Vijay Raghavan, C. A. Mayeda, and E.M. Meyerowitz, Mol. Cell. Biol. 10:5991-6002, 1990) are located within this 86-bp region. PMID:1903838

  19. 40 CFR 52.1394 - Section 110(a)(2) infrastructure requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Section 110(a)(2) infrastructure requirements. 52.1394 Section 52.1394 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... provisions which meet the requirements of CAA section 110(a)(1) and (2), elements (A), (B), (C) with...

  20. 77 FR 21913 - Approval and Promulgation of State Implementation Plans; Hawaii; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... NAAQS for fine particulate matter (PM 2.5 ). Section 110(a) of the CAA requires that each State adopt... AGENCY 40 CFR Part 52 Approval and Promulgation of State Implementation Plans; Hawaii; Infrastructure Requirements for the 1997 8-Hour Ozone and the 1997 and 2006 Fine Particulate Matter National Ambient...

  1. 78 FR 73442 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; State Boards Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... Plan (SIP). The SIP revision addresses the State Boards' requirements for all criteria pollutants of the National Ambient Air Quality Standards (NAAQS). EPA is approving this SIP revision in accordance... SIPs to comply with the requirements regarding State Boards. Section 110(a)(2)(E)(ii) of the CAA...

  2. 20 CFR 652.207 - How does a State meet the requirement for universal access to services provided under the Act?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ESTABLISHMENT AND FUNCTIONING OF STATE EMPLOYMENT... physical center, staff funded under the Act must provide core and applicable intensive services...

  3. 20 CFR 652.207 - How does a State meet the requirement for universal access to services provided under the Act?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ESTABLISHMENT AND FUNCTIONING OF STATE EMPLOYMENT... physical center, staff funded under the Act must provide core and applicable intensive services...

  4. Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency.

    PubMed

    Parsons, Barbara L; Delongchamp, Robert R; Beland, Frederick A; Heflich, Robert H

    2006-01-01

    DNA mismatch repair (MMR) deficiencies result in increased frequencies of spontaneous mutation and tumor formation. In the present study, we tested the hypothesis that a chemically-induced mutational response would be greater in a mouse with an MMR-deficiency than in the MMR-proficient mouse models commonly used to assay for chemical carcinogenicity. To accomplish this, the induction of H-ras codon 61 CAA-->AAA mutation was examined in Pms2 knockout mice (Pms2-/-, C57BL/6 background) and sibling wild-type mice (Pms2+/+). Groups of five or six neonatal male mice were treated with 0.3 micromol 4-aminobiphenyl (4-ABP) or the vehicle control, dimethylsulfoxide. Eight months after treatment, liver DNAs were isolated and analysed for levels of H-ras codon 61 CAA-->AAA mutation using allele-specific competitive blocker-PCR. In Pms2-proficient and Pms2-deficient mice, 4-ABP treatment caused an increase in mutant fraction (MF) from 1.65x10(-5) to 2.91x10(-5) and from 3.40x10(-5) to 4.70x10(-5), respectively. Pooling data from 4-ABP-treated and control mice, the approximately 2-fold increase in MF observed in Pms2-deficient as compared with Pms2-proficient mice was statistically significant (P=0.0207) and consistent with what has been reported previously in terms of induction of G:C-->T:A mutation in a Pms2-deficient background. Pooling data from both genotypes, the increase in H-ras MF in 4-ABP-treated mice, as compared with control mice, did not reach the 95% confidence level of statistical significance (P=0.0606). The 4-ABP treatment caused a 1.76-fold and 1.38-fold increase in average H-ras MF in Pms2-proficient and Pms2-deficient mice, respectively. Furthermore, the levels of induced mutation in Pms2-proficient and Pms2-deficient mice were nearly identical (1.26x10(-5) and 1.30x10(-5), respectively). We conclude that Pms2-deficiency does not result in an amplification of the H-ras codon 61 CAA-->AAA mutational response induced by 4-ABP.

  5. Determination of upstream boundary points on southeastern Washington streams and rivers under the requirements of the Shoreline Management Act of 1971

    USGS Publications Warehouse

    Higgins, Johnna L.

    2003-01-01

    Regulation of the shorelines of the State of Washington, as mandated by the Shoreline Management Act of 1971, requires knowledge of the locations on streams and river reaches where specific regulatory criteria are satisfied. The U.S. Geological Survey conducted a study in 1971 to determine the upstream boundary points of these reaches for many of the State's streams and rivers. Updated upstream boundary points were determined in the current study for all the streams and rivers in southeastern Washington that fall under the jurisdiction of the Shoreline Management Act of 1971. Upstream boundary point locations where the mean annual discharge equals 20 cubic feet per second were determined for 149 streams. In addition, upstream boundary point locations where the mean annual discharge equals 200 cubic feet per second or the drainage area equals 300 square miles were determined for 22 rivers. Boundary point locations were determined by application of multiple-linear-regression equations that relate mean annual discharge to drainage area and mean annual precipitation. Southeastern Washington was divided into five hydrologically distinct regions, and a separate regression equation was developed for each region. The regression equations are based on data for gaging stations with at least 10 years of record. The number of stations in the regression analysis for each of the five regions ranged from 5 to 33. The coefficient of determination, R2, of the regression equations ranged from 0.953 to 0.997. The equation for the Upper Yakima region had the lowest standard error, ranging from -7 to +9 percent for a regression estimate of 20 cubic feet per second. The equation for the Columbia Basin to Palouse region had the highest standard error, ranging from -36 to +55 percent for a regression estimate of 20 cubic feet per second. The approximate error in the location of an upstream boundary point can be calculated using the variables mean annual precipitation of the basin upstream

  6. Privacy Act

    EPA Pesticide Factsheets

    Learn about the Privacy Act of 1974, the Electronic Government Act of 2002, the Federal Information Security Management Act, and other information about the Environmental Protection Agency maintains its records.

  7. 24 CFR 1000.42 - Are the requirements of section 3 of the Housing and Urban Development Act of 1968 applicable?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Development Act of 1968 (12 U.S.C. 1701u) and HUD's implementing regulations in 24 CFR part 135, to the... Indian Self-Determination and Education Assistance Act (25 U.S.C. 450e(b)). Section 3 provides job... with section 101(k) of NAHASDA. (d) Applicability. For purposes of section 3, NAHASDA funding...

  8. FT-IR Spectroscopic Study of 1,5-Pentanedithiol and 1,6-Hexanedithiol Adsorbed on NaA, CaA and NaY Zeolites

    NASA Astrophysics Data System (ADS)

    Öztürk, Nuri; Çırak, Çağrı; Bahçeli, Semiha

    2005-09-01

    The adsorption of 1,5-pentanedithiol (1,5-PDT) and 1,6-hexanedithiol (1,6-HDT) in liquid phases on NaA (or 4A-type), CaA (or 5A-type) and NaY zeolites has been studied by using infrared spectroscopy. From the IR spectra it is found that the peak positions of the symmetric as well as the antisymmetric modes of the methylene (CH2) groups are observed at almost the same band values for the title dithiolates adsorbed on the A-type and NaY zeolites. On the other hand, the weak SH stretching vibration, observed for all samples, can be attributed to the sulphure atoms of 1,5-PDT and 1,6-HDT coordinatively adsorbed on cationic sites of the zeolites.

  9. Overcoming Geometry-Induced Stiffness with IMplicit-Explicit (IMEX) Runge-Kutta Algorithms on Unstructured Grids with Applications to CEM, CFD, and CAA

    NASA Technical Reports Server (NTRS)

    Kanevsky, Alex

    2004-01-01

    My goal is to develop and implement efficient, accurate, and robust Implicit-Explicit Runge-Kutta (IMEX RK) methods [9] for overcoming geometry-induced stiffness with applications to computational electromagnetics (CEM), computational fluid dynamics (CFD) and computational aeroacoustics (CAA). IMEX algorithms solve the non-stiff portions of the domain using explicit methods, and isolate and solve the more expensive stiff portions using implicit methods. Current algorithms in CEM can only simulate purely harmonic (up to lOGHz plane wave) EM scattering by fighter aircraft, which are assumed to be pure metallic shells, and cannot handle the inclusion of coatings, penetration into and radiation out of the aircraft. Efficient MEX RK methods could potentially increase current CEM capabilities by 1-2 orders of magnitude, allowing scientists and engineers to attack more challenging and realistic problems.

  10. The Kentucky Civil Rights Act: Explanation, the Act, Regulations.

    ERIC Educational Resources Information Center

    Kentucky State Commission on Human Rights, Frankfort.

    The Kentucky Civil Rights Act, introduced on January 4, 1966, enacted January 27, 1966 and effective July 1, 1966 is said to meet the requirements of the Federal Civil Rights Act of 1964. In 1968, the Act was amended to prohibit housing discrimination. In 1972, the coverage of the Act was extended to prohibit employment discrimination because of…

  11. Comprehensive Enforcement Action, Federal Court Filings Require R.I. State Government to Reduce Pollution and Resolve Longstanding Clean Water Act Violations

    EPA Pesticide Factsheets

    US has taken comprehensive enforcement action to resolve several years of significant noncompliance by the RIDOT with its obligations under the federal Clean Water Act and the permit that governs day-to-day operations of its stormwater drainage systems.

  12. Elementary and Secondary Education Act: Potential Effects of Changing Comparability Requirements. Report to the Chairman, Committee on Health, Education, Labor, and Pensions, U.S. Senate. GAO-11-258

    ERIC Educational Resources Information Center

    Scott, George A.

    2011-01-01

    For fiscal year 2010, Congress appropriated $14.5 billion for Title I, Part A of the Elementary and Secondary Education Act of 1965 (ESEA), which funds services to students in schools with high concentrations of students from low-income families. Title I, Part A includes several fiscal requirements, which are designed to prevent local school…

  13. Report: EPA Office of Inspector General’s Report on Reducing Fraud, Waste, and Abuse in the Small Business Innovative Research Program, as Required by the National Defense Authorization Act for Fiscal Year 2012, Pub. L. 112-81 (2012)

    EPA Pesticide Factsheets

    September 28, 2012. The EPA OIG is required by Section 5143 of the NDA Act for Fiscal Year 201 2, Pub. L. No. 112-81 (2012), to report on reducing vulnerability to fraud, waste and abuse in the Small Business Innovative Research (SBIR) program.

  14. 40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Provisions for Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and... with a 1-hour ozone design value equal to or greater than 0.121 ppm at the time the Administrator...

  15. 40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Provisions for Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and... with a 1-hour ozone design value equal to or greater than 0.121 ppm at the time the Administrator...

  16. 78 FR 46514 - Approval and Promulgation of Implementation Plans; Oregon: Infrastructure Requirements for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... provisions of the Oregon SIP are adequate to satisfy the above-mentioned infrastructure elements required by... meet the following CAA section 110(a)(2) infrastructure elements for the 1997 PM 2.5 , 2006 PM 2.5... regulations address operational and work practice standards, fuel burning equipment and fuel sulfur...

  17. 40 CFR 52.1833 - Section 110(a)(2) infrastructure requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Section 110(a)(2) infrastructure requirements. 52.1833 Section 52.1833 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... the 1997 and 2006 PM2.5 NAAQS: CAA section 110(a)(2)(A), (B), (C) with respect to minor NSR and...

  18. Title III list of lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and section 112(r) of the Clean Air Act, as ammended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990, April 1995

    SciTech Connect

    1995-04-01

    This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 313 of SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. It will also help firms determine whether they will be subject to accident prevention regulations under CAA section 112(r). Separate lists are also provided of Resource Conservation and Recovery Act (RCRA) waste streams and unlisted hazardous wastes, and of radionuclides reportable under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). These lists should be used as a reference tool, not as a definitive source of compliance information.

  19. Air permitting at military installations: Applying the EPA guidance for CAA major source determinations at DOD facilities

    SciTech Connect

    Bowers, T.L. Jr.

    1997-12-31

    On August 2, 1996, the Environmental Protection Agency issued guidance to its regional offices concerning Clean Air Act major source determinations for military installations. Congress traditionally targeted permitting efforts at major sources of air pollution to focus controls on the larger emitters. Many regulations depend on whether a source is major or not. The Title I New Source Review (NSR) program, the Title III Air Toxics program, and the Title V Operating Permits program all use major source as a differentiating point for regulations. The Prevention of Significant Deterioration rules (1980) are the basis of the definition used by NSR, Title V, and Air Toxics. The rules define major source as an emissions source or sources under common control, grouped by Standard Industrial Classification (SIC) code, and located on continuous or adjacent property. In addition, support facilities are grouped with another facility if >50% of the output of the support facility directly supplies the source. EPA Region III made a major source determination for Virginia at Fort Belvoir, grouping all pollutant emitting activities within the fenceline together. Prior to this determination, permit authorities had the discretion to determine the grouping of functions within the fenceline. Military Installations contain a diverse group of activities such as industrial operations, training ranges, dry cleaners, housing areas, and food establishments. The responsibility and control are also diverse and can be controlled by military, contractor, and leased services. This paper will provide methods which facilities and their contractors can use when negotiating permits with their permitting authority. The principal methods are to use separate control to separate Military Services or leased activities, and to use functionally distinct groupings other than SIC 97 (National Security) to classify activities at military installations.

  20. Sex Discrimination and Hair-Length Requirements Under Title VII of the Civil Rights Act of 1964 -- the Long and Short of It

    ERIC Educational Resources Information Center

    Golden, H. Bruce

    1974-01-01

    Since the passage of Title VII of the Civil Rights Act of 1964, an employer's rights to establish dress and appearance standards for employees has been challenged with increasing frequency as a discriminatory employment practice based upon sex. The majority of such cases have concerned the right of male employees to wear their hair as long as that…

  1. A Study of the Experiences of Alternatively Certified Special Education Teachers Related to the Requirements of the No Child Left Behind Act of 2001

    ERIC Educational Resources Information Center

    Veale, Natasha W.

    2010-01-01

    A No Child Left Behind Act of 2001 Title II audit found the state of North Carolina out of compliance with the definition of teacher quality for secondary special education teachers. The state specific Praxis exam and the Highly Objective, Uniform State Standard of Evaluation these teachers completed to earn certification to teach subject area…

  2. Report: U.S. Chemical Safety and Hazard Investigation Board Complied With Reporting Requirements of the Improper Payments Elimination and Recovery Act

    EPA Pesticide Factsheets

    Report #13-P-0177, March 12, 2013. CSB is fully compliant with the reporting requirements of IPERA, which require all agencies to periodically review all programs and activities that may be susceptible to significant improper payments.

  3. 76 FR 24421 - Approval and Promulgation of Air Quality Implementation Plans; New Mexico; Section 110(a)(2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Clean Air Act (CAA or Act) that address the infrastructure elements specified in the CAA section 110(a... under section 110 and part C of the Act. DATES: Comments must be received on or before June 1, 2011.... Background A. What are the National Ambient Air Quality Standards? Section 109 of the Act requires EPA...

  4. 76 FR 29680 - Approval and Disapproval and Promulgation of State Implementation Plan Revisions; Infrastructure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... that the SIP meets the requirements of Sections 110(a)(1) and (2) of the Clean Air Act (CAA) for the... December 7, 2007 and December 10, 2009. EPA does not propose to act on the State's May 25, 2007 submission...: (i) The words or initials Act or CAA mean or refer to the Clean Air Act, unless the context...

  5. 20 CFR 652.210 - What are the Act's requirements for administration of the work test and assistance to UI claimants?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... appropriate to facilitate their earliest return to work; (2) UI claimants requiring assistance in seeking work... administration of the work test and assistance to UI claimants? 652.210 Section 652.210 Employees' Benefits... requirements for administration of the work test and assistance to UI claimants? (a) State UI law or...

  6. Guidance on Developing Fee Programs Required by Clean Air Act Section 185 for the 1997 1-hour Ozone National Ambient Air Quality Standards (NAAQS)

    EPA Pesticide Factsheets

    This January 2010 memorandum provides additional guidance on fee collection programs for the 1997 1-hour ozone NAAQS, which are required as anti-backsliding measures during transition to the 1997 8-hour ozone standard.

  7. Applying the Clean Air Act to municipal solid waste landfills

    SciTech Connect

    Heitz, D.R.; Romzick, P.G.

    1998-12-31

    On March 12, 1996, the EPA promulgated the new Source Performance Standards (NSPS) for Municipal Solid Waste (MSW) Landfills, the first federal air regulation specifically for MSW landfills. Landfills subject to this regulation which exceeded the threshold design capacity also became subject to the Title V operating permit program. This began the application of the Clean Air Act (CAA) to most of these nontraditional air sources. Unlike landfills, typical air sources have easily defined input capacities that correspond to potential emissions while the process creates a product or output. All these concepts are difficult and confusing to apply to MSW landfills. Applicability of the following CAA regulations are specifically addressed in this paper: NSPS for MSW landfills; new Source Review (NSR)/Prevention of Significant Deterioration (PSD); landfill Maximum Achievable Control Technologies (MACT); 112(g) Modification of Major Sources of Hazardous Air Pollutants (HAP); 112(r) Accidental Release Prevention; and Title V. Along with summarizing the potential applicability of each, the main issues are presented along with the current information on the regulations.

  8. 78 FR 17403 - No FEAR Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ... AGENCY No FEAR Act Notice AGENCY: Federal Housing Finance Agency. ACTION: Notice. SUMMARY: The Federal... and Federal Employee Antidiscrimination and Retaliation Act of 2002, which is now known as the No FEAR Act (No FEAR Act), (Pub. L. 107-174). One purpose of the No FEAR Act is to require that...

  9. [Complementary to notification required by the national Protection against Infection Act. State-specific mandatory infectious disease notification in Saxony-Anhalt].

    PubMed

    Oppermann, H; Thriene, B; Zaumseil, S

    2005-09-01

    In May 1991 a decree supplementing the federal Epidemic Law concerning the mandatory notification of communicable diseases was implemented by the Ministry of Health in Saxony-Anhalt. This was updated and newly implemented in 1997. With implementation of the national Protection against Infection Act in 2001 further amendment of the state regulation (published in April 2005) be came necessary. The following diseases or laboratory evidence of the underlying pathogens, respectively, will now be notifiable with inclusion of the affected individual's name: aseptic meningitis, mumps, rubella, varicella, epidemickera to conjunctivitis, pertussis, and pneumococcal meningitis. The possibility of preventing further spread of the pathogen to others though immediate implementation of preventive measures by the public health service justifies notification of the individual's name. Furthermore, the epidemiological situation is to be monitored and evaluated. This also applies to Lyme disease, which will be anonymously notifiable. Particular emphasis is placed on vaccine-preventable diseases in the state regulation for mandatory notification in Saxony-Anhalt, since priority is placed on attaining the health goal "age-appropriate vaccination status in over 90% of the population". The state-specific notification regulation of Saxony-Anhalt has worked well in preventing and controlling communicable diseases. It is a source of reliable data, which may be helpful in the discussion regarding the amendment of the Protection against Infection Act. Non-anonymous notification should be enforced nationally at least for all vaccine-preventable diseases for which a post-exposure vaccination is recommended by the Standing Committee on Vaccination (STIKO).

  10. 76 FR 28934 - Approval and Disapproval and Promulgation of State Implementation Plan Revisions; Infrastructure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... that the SIP meets the requirements of sections 110(a)(1) and (2) of the Clean Air Act (CAA) for the..., 2009. EPA does not propose to act on the State's November 28, 2007 and December 22, 2009, submissions... giving meaning to certain words or initials as follows: (i) The words or initials Act or CAA mean...

  11. 75 FR 64773 - Study Required by Section 989G(b) of the Dodd-Frank Act Regarding Compliance With Section 404(b...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... financial reporting,\\8\\ and the January 2009 Guidance on Monitoring Internal Control Systems,\\9\\ have... with respect to a company's internal control over financial reporting. The required study will not... management's responsibility for reporting on the effectiveness of internal control over financial...

  12. Acting Atoms.

    ERIC Educational Resources Information Center

    Farin, Susan Archie

    1997-01-01

    Describes a fun game in which students act as electrons, protons, and neutrons. This activity is designed to help students develop a concrete understanding of the abstract concept of atomic structure. (DKM)

  13. Clean Air Act 1990 Amendments

    SciTech Connect

    Stensvaag, J.M.

    1991-01-01

    This book is an analysis of the 1990 Amendments to the Clean Air Act that includes compliance requirements, the new operating permit system, the enhanced enforcement provisions and criminal penalties, potential for citizen enforcement, and the increased reporting requirements. Also analyzed are the new defenses such as permit compliance and protection of employees acting within the direction of employers.

  14. The application of genetic information for regulatory standard setting under the clean air act: a decision-analytic approach.

    PubMed

    Cullen, Alison C; Corrales, Mark A; Kramer, C Bradley; Faustman, Elaine M

    2008-08-01

    In 2002, the U.S. Environmental Protection Agency (EPA) released an "Interim Policy on Genomics," stating a commitment to developing guidance on the inclusion of genetic information in regulatory decision making. This statement was followed in 2004 by a document exploring the potential implications. Genetic information can play a key role in understanding and quantifying human susceptibility, an essential step in many of the risk assessments used to shape policy. For example, the federal Clean Air Act (CAA) requires EPA to set National Ambient Air Quality Standards (NAAQS) for criteria pollutants at levels to protect even sensitive populations from adverse health effects with an adequate margin of safety. Asthmatics are generally regarded as a sensitive population, yet substantial research gaps in understanding genetic susceptibility and disease have hindered quantitative risk analysis. This case study assesses the potential role of genomic information regarding susceptible populations in the NAAQS process for fine particulate matter (PM(2.5)) under the CAA. In this initial assessment, we model the contribution of a single polymorphism to asthma risk and mortality risk; however, multiple polymorphisms and interactions (gene-gene and gene-environment) are known to play key roles in the disease process. We show that the impact of new information about susceptibility on estimates of population risk or average risk derived from large epidemiological studies depends on the circumstances. We also suggest that analysis of a single polymorphism, or other risk factor such as health status, may or may not change estimates of individual risk enough to alter a particular regulatory decision, but this depends on specific characteristics of the decision and risk information. We also show how new information about susceptibility in the context of the NAAQS for PM(2.5) could have a large impact on the estimated distribution of individual risk. This would occur if a group were

  15. 77 FR 34898 - Approval and Promulgation of Implementation Plans; Mississippi; 110(a)(1) and (2) Infrastructure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ...) and (2) of the Clean Air Act (CAA or the Act) for the 1997 annual and 2006 24-hour fine particulate... comply with the requirements respecting State Boards pursuant to section 128 of the Act, and...

  16. 77 FR 62452 - Approval and Promulgation of Implementation Plans; State of Arizona; Prevention of Air Pollution...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... Air Pollution Emergency Episodes AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule... address the requirements regarding air pollution emergency episodes in Clean Air Act (CAA or Act). DATES... Arizona to address the requirements regarding air pollution emergency episodes in CAA section...

  17. 75 FR 42130 - Notice of Lodging of Consent Decree Under the Clean Air Act; Clean Water Act; Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ...''); Clean Water Act, 33 U.S.C. 1311 to 1387 (``CWA''); Resource Conservation and Recovery Act (``RCRA''), 42... of Lodging of Consent Decree Under the Clean Air Act; Clean Water Act; Resource Conservation and Recovery Act; Safe Drinking Water Act; Toxic Substances Control Act; and the Reporting Requirements of...

  18. National School Lunch Program and School Breakfast Program: Nutrition Standards for All Foods Sold in School as Required by the Healthy, Hunger-Free Kids Act of 2010. Final rule and interim final rule.

    PubMed

    2016-07-29

    This rule adopts as final, with some modifications, the National School Lunch Program and School Breakfast Program regulations set forth in the interim final rule published in the Federal Register on June 28, 2013. The requirements addressed in this rule conform to the provisions in the Healthy, Hunger-Free Kids Act of 2010 regarding nutrition standards for all foods sold in schools, other than food sold under the lunch and breakfast programs. Most provisions of this final rule were implemented on July 1, 2014, a full year subsequent to publication of the interim final rule. This was in compliance with section 208 of the Healthy, Hunger-Free Kids Act of 2010, which required that State and local educational agencies have at least one full school year from the date of publication of the interim final rule to implement the competitive food provisions. Based on comments received on the interim final rule and implementation experience, this final rule makes a few modifications to the nutrition standards for all foods sold in schools implemented on July 1, 2014. In addition, this final rule codifies specific policy guidance issued after publication of the interim rule. Finally, this rule retains the provision related to the standard for total fat as interim and requests further comment on this single standard.

  19. PUNCTATE VASCULAR EXPRESSION1 Is a Novel Maize Gene Required for Leaf Pattern Formation That Functions Downstream of the Trans-Acting Small Interfering RNA Pathway1[C][W][OA

    PubMed Central

    Zhang, Xiaolan; Douglas, Ryan N.; Strable, Josh; Lee, Michelle; Buckner, Brent; Janick-Buckner, Diane; Schnable, Patrick S.; Timmermans, Marja C.P.; Scanlon, Michael J.

    2012-01-01

    The maize (Zea mays) gene RAGGED SEEDLING2-R (RGD2-R) encodes an ARGONAUTE7-like protein required for the biogenesis of trans-acting small interfering RNA, which regulates the accumulation of AUXIN RESPONSE FACTOR3A transcripts in shoots. Although dorsiventral polarity is established in the narrow and cylindrical leaves of rgd2-R mutant plants, swapping of adaxial/abaxial epidermal identity occurs and suggests a model wherein RGD2 is required to coordinate dorsiventral and mediolateral patterning in maize leaves. Laser microdissection-microarray analyses of the rgd2-R mutant shoot apical meristem identified a novel gene, PUNCTATE VASCULAR EXPRESSION1 (PVE1), that is down-regulated in rgd2-R mutant apices. Transcripts of PVE1 provide an early molecular marker for vascular morphogenesis. Reverse genetic analyses suggest that PVE1 functions during vascular development and in mediolateral and dorsiventral patterning of maize leaves. Molecular genetic analyses of PVE1 and of rgd2-R;pve1-M2 double mutants suggest a model wherein PVE1 functions downstream of RGD2 in a pathway that intersects and interacts with the trans-acting small interfering RNA pathway. PMID:22669891

  20. In vitro transcription of a Drosophila U1 small nuclear RNA gene requires TATA box-binding protein and two proximal cis-acting elements with stringent spacing requirements.

    PubMed Central

    Zamrod, Z; Tyree, C M; Song, Y; Stumph, W E

    1993-01-01

    Transcription of a Drosophila U1 small nuclear RNA gene was functionally analyzed in cell extracts derived from 0- to 12-h embryos. Two promoter elements essential for efficient initiation of transcription in vitro by RNA polymerase II were identified. The first, termed PSEA, is located between positions -41 and -61 relative to the transcription start site, is crucial for promoter activity, and is the dominant element for specifying the transcription initiation site. PSEA thus appears to be functionally homologous to the proximal sequence element of vertebrate small nuclear RNA genes. The second element, termed PSEB, is located at positions -25 to -32 and is required for an efficient level of transcription initiation because mutation of PSEB, or alteration of the spacing between PSEA and PSEB, severely reduced transcriptional activity relative to that of the wild-type promoter. Although the PSEB sequence does not have any obvious sequence similarity to a TATA box, conversion of PSEB to the canonical TATA sequence dramatically increased the efficiency of the U1 promoter and simultaneously relieved the requirement for the upstream PSEA. Despite these effects, introduction of the TATA sequence into the U1 promoter had no effect on the choice of start site or on the RNA polymerase II specificity of the promoter. Finally, evidence is presented that the TATA box-binding protein is required for transcription from the wild-type U1 promoter as well as from the TATA-containing U1 promoter. Images PMID:8355718

  1. Balancing Act

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2007-01-01

    For some administrators and planners, designing and building education facilities may sometimes seem like a circus act--trying to project a persona of competence and confidence while juggling dozens of issues. Meanwhile, the audience--students, staff members and taxpayers--watch and wait with anticipation in hopes of getting what they paid for and…

  2. In vivo RNA localization of I factor, a non-LTR retrotransposon, requires a cis-acting signal in ORF2 and ORF1 protein

    PubMed Central

    del Carmen Seleme, Maria; Disson, Olivier; Robin, Stéphanie; Brun, Christine; Teninges, Danielle; Bucheton, Alain

    2005-01-01

    According to the current model of non-LTR retrotransposon (NLR) mobilization, co-expression of the RNA transposition intermediate, and the proteins it encodes (ORF1p and ORF2p), is a requisite for the formation of cytoplasmic ribonucleoprotein complexes which contain necessary elements to complete a retrotransposition cycle later in the nucleus. To understand these early processes of NLR mobilization, here we analyzed in vivo the protein and RNA expression patterns of the I factor, a model NLR in Drosophila. We show that ORF1p and I factor RNA, specifically produced during transposition, are co-expressed and tightly co-localize with a specific pattern (Loc+) exclusively in the cytoplasm of germ cells permissive for retrotransposition. Using an ORF2 mutated I factor, we show that ORF2p plays no role in the Loc+ patterning. With deletion derivatives of an I factor we define an RNA localization signal required to display the Loc+ pattern. Finally, by complementation experiments we show that ORF1p is necessary for the efficient localization of I factor RNA. Our data suggest that ORF1p is involved in proper folding and stabilization of I factor RNA for efficient targeting, through Loc+ patterning, to the nuclear neighborhood where downstream steps of the retrotransposition process occur. PMID:15687386

  3. Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos

    PubMed Central

    Medley, Jeffrey C.; Kabara, Megan M.; Stubenvoll, Michael D.; DeMeyer, Lauren E.

    2017-01-01

    ABSTRACT Centrosomes are the primary microtubule-organizing centers that orchestrate microtubule dynamics during the cell cycle. The correct number of centrosomes is pivotal for establishing bipolar mitotic spindles that ensure accurate segregation of chromosomes. Thus, centrioles must duplicate once per cell cycle, one daughter per mother centriole, the process of which requires highly coordinated actions among core factors and modulators. Protein phosphorylation is shown to regulate the stability, localization and activity of centrosome proteins. Here, we report the function of Casein kinase II (CK2) in early Caenorhabditis elegans embryos. The catalytic subunit (KIN-3/CK2α) of CK2 localizes to nuclei, centrosomes and midbodies. Inactivating CK2 leads to cell division defects, including chromosome missegregation, cytokinesis failure and aberrant centrosome behavior. Furthermore, depletion or inhibiting kinase activity of CK2 results in elevated ZYG-1 levels at centrosomes, restoring centrosome duplication and embryonic viability to zyg-1 mutants. Our data suggest that CK2 functions in cell division and negatively regulates centrosome duplication in a kinase-dependent manner. PMID:27881437

  4. The USA PATRIOT Act.

    ERIC Educational Resources Information Center

    Minow, Mary; Coyle, Karen; Kaufman, Paula

    2002-01-01

    Explains the USA PATRIOT (Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism) Act, passed after the September 11 terrorist attacks, and its implications for libraries and patron records. Considers past dealings with the FBI; court orders; search warrants; wiretaps; and subpoenas. Includes:…

  5. 24 CFR 570.614 - Architectural Barriers Act and the Americans with Disabilities Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Architectural Barriers Act and the... GRANTS Other Program Requirements § 570.614 Architectural Barriers Act and the Americans with Disabilities Act. (a) The Architectural Barriers Act of 1968 (42 U.S.C. 4151-4157) requires certain Federal...

  6. 2009 Strategic Plan for Autism Spectrum Disorder Research. NIH Publication No. 09-7465

    ERIC Educational Resources Information Center

    Interagency Autism Coordinating Committee, 2009

    2009-01-01

    In response to the heightened societal concern over autism spectrum disorder (ASD), Congress passed the Combating Autism Act (CAA) of 2006 (P.L. 109-416). Through this Act, Congress intended to rapidly increase, accelerate the pace and improve coordination of scientific discovery in ASD research. The CAA requires the Interagency Autism…

  7. Arts Require Timely Service (ARTS) Act

    THOMAS, 111th Congress

    Rep. Berman, Howard L. [D-CA-28

    2009-03-30

    04/27/2009 Referred to the Subcommittee on Immigration, Citizenship, Refugees, Border Security, and International Law. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  8. Medical Waste Act. Requires physician compliance.

    PubMed

    Chadzynki, L

    1991-07-01

    In Michigan, the medical care community has a long history of carefully managing infectious medical wastes within their facilities to control communicable diseases. Never the less, concerns have surfaced about health risks posed by medical waste because of the notoriety of reported incidents of improperly disposed medical waste that led to the promulgation of emergency rules and now permanent statutes. As the environment reemerges as a national issue, the proper disposal of medical waste remains, at the very least, a highly visible and volatile part of this nation's solid waste crisis. To better develop appropriate controls for dealing with regulated medical waste, we will need to work together. Journal articles such as this provide an important opportunity to share and more forward our understanding of this problem so that we may all enjoy a safer and better environment. Proper handling and disposal of medical waste will remain a public issue as long as wastes believed to be of medical origin are found on beaches or at unauthorized storage or disposal locations. Hence, compliance with the regulations for the handling, storing, treating, transporting and ultimate disposal of regulated medical waste by providers of health care in Michigan must be observed.

  9. Clean Water Act Analytical Methods

    EPA Pesticide Factsheets

    EPA publishes laboratory analytical methods (test procedures) that are used by industries and municipalities to analyze the chemical, physical and biological components of wastewater and other environmental samples required by the Clean Water Act.

  10. 7 CFR 926.2 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE DATA COLLECTION, REPORTING AND RECORDKEEPING REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.2 Act. Act...

  11. 75 FR 62613 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... securities (ABS) to perform a review of the assets underlying the ABS and disclose information relating to... 15E(s)(4)(A) of the Exchange Act as added by Section 932 of the Act, which requires an ABS issuer...

  12. Information on the Interstate Transport Good Neighbor Provision for the 2012 Fine Particulate Matter (PM) National Ambient Air Quality Standards (NAAQS) under Clean Air Act (CAA) Section 110(a)(2)(D)(i)(I)

    EPA Pesticide Factsheets

    The purpose of this March 2016 memorandum is to provide information to EPA regional offices and states as they develop and review SIPs that address the interstate transport Good Neighbor provision as it pertains to the PM2.5 NAAQS

  13. 76 FR 13944 - Approval and Promulgation of Air Quality Implementation Plans; State of California; Regional Haze...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... (CAA or ``Act'') and EPA's rules that require states to prevent any future and remedy any existing..., and (c) interfere with measures required under Part C of the CAA to prevent significant deterioration... transport. The SIP must prevent sources in the state from emitting pollutants in amounts which will:...

  14. 78 FR 21281 - Approval and Promulgation of Implementation Plans; State of Missouri; Infrastructure SIP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ...EPA is proposing action on four Missouri State Implementation Plan (SIP) submissions. First, EPA is proposing to approve portions of two SIP submissions from the State of Missouri addressing the applicable requirements of Clean Air Act (CAA) for the 1997 and 2006 National Ambient Air Quality Standards (NAAQS) for fine particulate matter (PM2.5). The CAA requires that each state......

  15. Comparison of sodium naphthenate and air-ionization corona discharge as surface treatments for the ethylene-tetrafluoroethylene polymer (ETFE) to improve adhesion between ETFE and acrylonitrile-butadiene-styrene polymer (ABS) in the presence of a cyanoacrylate adhesive (CAA)

    NASA Astrophysics Data System (ADS)

    Lucía Johanning-Solís, Ana; Stradi-Granados, Benito A.

    2014-09-01

    This study compares two ethylene-tetrafluoroethylene (ETFE) surface activation treatments, namely chemical attack with a solution of sodium naphthenate and plasma erosion via air-ionization corona discharge in order to improve the adhesive properties of the ETFE. An experimental design was prepared for both treatments in order to assess the effect of the treatment characteristics on the tensile load needed to break the bond between the ETFE and the acrylonitrile-butadiene-styrene polymer (ABS) formed with a cyanoacrylate adhesive (CAA) applied between them. The reason for the selection of this problem is that both polymers are frequently used in the biomedical industry for their properties, and they need to be joined firmly in biomedical devices, and the cyanoacrylate adhesive is the adhesive traditionally used for fluoropolymers, in this case the ETFE, and the same CAA has also shown good adhesion with ABS. However, the strength of the bond for the triplet ETFE-CAA-ABS has not been reported and the improvement of the strength of the bond with surface treatments is not found in scholarly journals for modern medical devices such as stents and snares. Both treatments were compared based on the aforementioned design of experiments. The case where ETFE receives no surface treatment serves as the reference. The results indicated that the three factors evaluated (initial drying of the material, temperature of the chemical bath, and immersion time), and their interactions have no significant effect over the tensile load at failure (tensile strength) of the adhesive bond being evaluated. For the air-ionization corona discharge treatment, two factors were evaluated: discharge exposition time and air pressure. The results obtained from this experimental design indicate that there is no significant difference between the levels of the factors evaluated. These results were unexpected as the ranges used were representative of the maximum ranges permissible in manufacturing

  16. European Transportation Requirements for the Backhaul of Personnel/Cargo (ETRANS) Study

    DTIC Science & Technology

    1991-09-01

    G044) .A45: 𔃼. K -Kill D45: (F1) +±400D6 E45: (FI) +E40Ot6 F45: (FI) +F& O *F6 G45: (Ft) +t;i40G6 H45: (FI) WSUM(0&5..GOY) 1-11--3 CAA-SR-91-11 A46...aQPpo• o ••d 92-03846 for" pliblic IeQ,21•:.e cl d ’iala; itsSdishibutl-i b rl ia iteel.m• III$ 11- . . .- DISCLAIMER The findings of this report are...REQUIREMENTS FOR THE BACKHAUL SUDYCAAF O PERSONNEL/CARGO (ETRANS) CAA-SR-91-11 SsrA,• "STUDY THE REASON FOR PERFORMING THE STUDY was to determine if

  17. 3 CFR - Freedom of Information Act

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Heads of Executive Departments and Agencies A democracy requires accountability, and... disinfectants.” In our democracy, the Freedom of Information Act (FOIA), which encourages accountability...

  18. 75 FR 29 - Privacy Act, Government in the Sunshine Act, Freedom of Information Act (“FOIA”), and Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... Information Act (``FOIA''), and Federal Election Campaign Act (``FECA'') Rules; Corrections AGENCY: Federal..., 5 U.S.C. 552, and the Federal Election Campaign Act (``FECA'') of 1971, as amended, 2 U.S.C. 431, et... requirements. 11 CFR Part 104 Campaign funds, Political committees and parties, Reporting and...

  19. 16 CFR 305.4 - Prohibited acts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING RULEâ) General § 305.4 Prohibited acts... part with a marking, label, hang tag, or energy fact sheet which conforms to the provisions of the Act... or render illegible any marking or label required to be provided with such product by this part....

  20. 75 FR 57330 - Community Reinvestment Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... Office of Thrift Supervision Community Reinvestment Act AGENCY: Office of Thrift Supervision (OTS... collection. Title of Proposal: Community Reinvestment Act. OMB Number: 1550-0012. Form Number: N/A. Description: The Community Reinvestment Act regulation requires the OTS, as well as the Office of...

  1. 75 FR 7312 - No FEAR Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... No FEAR Act Notice Summary: 5 CFR part 724.202 requires that each Federal agency provide notice to... notice in the Federal Register. No FEAR Act Notice On May 15, 2002, Congress enacted the Notification and Federal Employee Antidiscrimination and Retaliation Act of 2002, which is now known as the No FEAR...

  2. 77 FR 27532 - No FEAR Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... FOR AFGHANISTAN RECONSTRUCTION No FEAR Act Notice AGENCY: Special Inspector General for Afghanistan... Reconstruction's (SIGAR) ``No FEAR Act Notice'' Federal Register publication obligations, as required by the... FEAR) Act and by the Office of Personnel Management implementing regulations at 5 CFR 724.202, to...

  3. 75 FR 61994 - Privacy Act; Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... Office of the Secretary 31 CFR Part 1 RIN 1505-AC25 Privacy Act; Implementation AGENCY: Office of Foreign... requirements of the Privacy Act of 1974, as amended, the Department of the Treasury is amending its regulations... records by revising the number and title of the Privacy Act system of records for which an exemption...

  4. 76 FR 71293 - Privacy Act; Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ... Office of the Secretary 31 CFR Part 1 RIN 1505-AC37 Privacy Act; Implementation AGENCY: Office of the Secretary, Treasury. ACTION: Proposed rule. SUMMARY: In accordance with the requirements of the Privacy Act... Identification Number Records'' from certain provisions of the Privacy Act. DATES: Comments must be received...

  5. An analysis of candidates for addition to the Clean Air Act list of hazardous air pollutants.

    PubMed

    Lunder, Sonya; Woodruff, Tracey J; Axelrad, Daniel A

    2004-02-01

    There are 188 air toxics listed as hazardous air pollutants (HAPs) in the Clean Air Act (CAA), based on their potential to adversely impact public health. This paper presents several analyses performed to screen potential candidates for addition to the HAPs list. We analyzed 1086 HAPs and potential HAPs, including chemicals regulated by the state of California or with emissions reported to the Toxics Release Inventory (TRI). HAPs and potential HAPs were ranked by their emissions to air, and by toxicity-weighted (tox-wtd) emissions for cancer and noncancer, using emissions information from the TRI and toxicity information from state and federal agencies. Separate consideration was given for persistent, bioaccumulative toxins (PBTs), reproductive or developmental toxins, and chemicals under evaluation for regulation as toxic air contaminants in California. Forty-four pollutants were identified as candidate HAPs based on three ranking analyses and whether they were a PBT or a reproductive or developmental toxin. Of these, nine qualified in two or three different rankings (ammonia [NH3], copper [Cu], Cu compounds, nitric acid [HNO3], N-methyl-2-pyrrolidone, sulfuric acid [H2SO4], vanadium [V] compounds, zinc [Zn], and Zn compounds). This analysis suggests further evaluation of several pollutants for possible addition to the CAA list of HAPs.

  6. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.205-1 SAFETY Act Considerations. (a) SAFETY Act applicability. Requiring activities should review requirements to identify potential technologies that...

  7. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.205-1 SAFETY Act Considerations. (a) SAFETY Act applicability. Requiring activities should review requirements to identify potential technologies that...

  8. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.205-1 SAFETY Act Considerations. (a) SAFETY Act applicability. Requiring activities should review requirements to identify potential technologies that...

  9. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.205-1 SAFETY Act Considerations. (a) SAFETY Act applicability. Requiring activities should review requirements to identify potential technologies that...

  10. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.205-1 SAFETY Act Considerations. (a) SAFETY Act applicability. Requiring activities should review requirements to identify potential technologies that...

  11. 75 FR 22804 - Submission for OMB Review; American Recovery and Reinvestment Act-One-Time Reporting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ...; American Recovery and Reinvestment Act--One-Time Reporting, Compensation Requirements AGENCIES: Department... Recovery and Reinvestment Act--One-time Reporting, Compensation Requirements published in the...

  12. Program management assessment of Federal Facility Compliance Agreement regarding CAA-40 C.F.R. Part 61, Subpart H at the Los Alamos National Laboratory

    SciTech Connect

    1997-01-01

    An assessment of Los Alamos National Laboratory`s management system related to facility compliance with an element of the Clean Air Act was performed under contract by a team from Northern Arizona University. More specifically, a Federal Facilities Compliance Agreement (FFCA) was established in 1996 to bring the Laboratory into compliance with emissions standards of radionuclides, commonly referred to as Rad/NESHAP. In the fall of 1996, the four-person team of experienced environmental managers evaluated the adequacy of relevant management systems to implement the FFCA provisions. The assessment process utilized multiple procedures including document review, personnel interviews and re-interviews, and facility observations. The management system assessment was completed with a meeting among team members, Laboratory officials and others on November 1, 1996 and preparation of an assessment report.

  13. Navigation and vessel inspection circular No. 1-81. Guidance for enforcement of the requirements of the Port and Tanker Safety Act of 1978 (PTSA) pertaining to SBT, CBT, COW, IGS, steering gear, and navigation equipment for tank vessels. Final report

    SciTech Connect

    1981-02-18

    The purpose of this NVC and its enclosures is to provide guidance and information pertaining to: Enforcement of the Requirements of the Port and Tanker Safety Act of 1978 (PTSA) Pertaining to SBT, CBT, COW systems, IGS, Steering Gear, and Navigation Equipment for Tank Vessels.

  14. Response to Question Regarding the Use of the Growth Allowance Contained in Part D SIPs Under the CAA for Areas Included in the Post 1987 SIP Call

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  15. Applicability of Section 169 of the CAA (PSD) in Respect to the Control of Hydrogen Sulfide Emissions from New Geothermal Power Plants in California

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. A Novel Proteinase, SNOWY COTYLEDON4, Is Required for Photosynthetic Acclimation to Higher Light Intensities in Arabidopsis1[W

    PubMed Central

    Albrecht-Borth, Verónica; Kauss, Dominika; Fan, Dayong; Hu, Yuanyuan; Collinge, Derek; Marri, Shashikanth; Liebers, Monique; Apel, Klaus; Pfannschmidt, Thomas; Chow, Wah S.; Pogson, Barry J.

    2013-01-01

    Excess light can have a negative impact on photosynthesis; thus, plants have evolved many different ways to adapt to different light conditions to both optimize energy use and avoid damage caused by excess light. Analysis of the Arabidopsis (Arabidopsis thaliana) mutant snowy cotyledon4 (sco4) revealed a mutation in a chloroplast-targeted protein that shares limited homology with CaaX-type endopeptidases. The SCO4 protein possesses an important function in photosynthesis and development, with point mutations rendering the seedlings and adult plants susceptible to photooxidative stress. The sco4 mutation impairs the acclimation of chloroplasts and their photosystems to excess light, evidenced in a reduction in photosystem I function, decreased linear electron transfer, yet increased nonphotochemical quenching. SCO4 is localized to the chloroplasts, which suggests the existence of an unreported type of protein modification within this organelle. Phylogenetic and yeast complementation analyses of SCO4-like proteins reveal that SCO4 is a member of an unknown group of higher plant-specific proteinases quite distinct from the well-described CaaX-type endopeptidases RAS Converting Enzyme1 (RCE1) and zinc metallopeptidase STE24 and lacks canonical CaaX activity. Therefore, we hypothesize that SCO4 is a novel endopeptidase required for critical protein modifications within chloroplasts, influencing the function of proteins involved in photosynthesis required for tolerance to excess light. PMID:23940253

  17. 75 FR 58389 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One Time Reporting Requirements for Prime Contractors AGENCY: Department of Defense (DOD), General Services... American Recovery and Reinvestment Act-Reporting Requirements--One Time Reporting Requirements for...

  18. The Indian Child Welfare Act.

    ERIC Educational Resources Information Center

    Steward, Katy Jo

    The Indian Child Welfare Act of 1978 (I.C.W.A.) is federal legislation which preempts state law whenever Indian children may be removed from their families. The I.C.W.A. permits Indian tribal courts to decide the future of Indian children, establishes minimum federal standards for removal of Indian children from their families, requires that…

  19. Community Environmental Response Facilitation Act

    EPA Pesticide Factsheets

    To amend the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 to require the Federal Government, before termination of Federal activities on any real property owned by the Government, to identify real property where no hazardous substance was stored, released, or disposed of.

  20. Severe and rapidly progressing cognitive phenotype in a SCA17-family with only marginally expanded CAG/CAA repeats in the TATA-box binding protein gene: A case report

    PubMed Central

    2012-01-01

    Background The autosomal dominant spinocerebellar ataxias (SCAs) confine a group of rare and heterogeneous disorders, which present with progressive ataxia and numerous other features e.g. peripheral neuropathy, macular degeneration and cognitive impairment, and a subset of these disorders is caused by CAG-repeat expansions in their respective genes. The diagnosing of the SCAs is often difficult due to the phenotypic overlap among several of the subtypes and with other neurodegenerative disorders e.g. Huntington’s disease. Case presentation We report a family in which the proband had rapidly progressing cognitive decline and only subtle cerebellar symptoms from age 42. Sequencing of the TATA-box binding protein gene revealed a modest elongation of the CAG/CAA-repeat of only two repeats above the non-pathogenic threshold of 41, confirming a diagnosis of SCA17. Normally, repeats within this range show reduced penetrance and result in a milder disease course with slower progression and later age of onset. Thus, this case presented with an unusual phenotype. Conclusions The current case highlights the diagnostic challenge of neurodegenerative disorders and the need for a thorough clinical and paraclinical examination of patients presenting with rapid cognitive decline to make a precise diagnosis on which further genetic counseling and initiation of treatment modalities can be based. PMID:22889412

  1. OIeylamine; Testing Requirements

    EPA Pesticide Factsheets

    EPA is issuing a final rule under section 4(a) of the Toxic Substances Control Act (TSCA) requiring manufacturers and processors of oleylamine (9-octadecenylamine or ODA, CAS Number 112-90—3) to test this chemical.

  2. ACTS broadband aeronautical experiment

    NASA Technical Reports Server (NTRS)

    Abbe, Brian S.; Jedrey, Thomas C.; Estabrook, Polly; Agan, Martin J.

    1993-01-01

    In the last decade, the demand for reliable data, voice, and video satellite communication links between aircraft and ground to improve air traffic control, airline management, and to meet the growing demand for passenger communications has increased significantly. It is expected that in the near future, the spectrum required for aeronautical communication services will grow significantly beyond that currently available at L-band. In anticipation of this, JPL is developing an experimental broadband aeronautical satellite communications system that will utilize NASA's Advanced Communications Technology Satellite (ACTS) as a satellite of opportunity and the technology developed under JPL's ACTS Mobile Terminal (AMT) Task to evaluate the feasibility of using K/Ka-band for these applications. The application of K/Ka-band for aeronautical satellite communications at cruise altitudes is particularly promising for several reasons: (1) the minimal amount of signal attenuation due to rain; (2) the reduced drag due to the smaller K/Ka-band antennas (as compared to the current L-band systems); and (3) the large amount of available bandwidth. The increased bandwidth available at these frequencies is expected to lead to significantly improved passenger communications - including full-duplex compressed video and multiple channel voice. A description of the proposed broadband experimental system will be presented including: (1) applications of K/Ka-band aeronautical satellite technology to U.S. industry; (2) the experiment objectives; (3) the experiment set-up; (4) experimental equipment description; and (5) industrial participation in the experiment and the benefits.

  3. 45 CFR 2543.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Resource Conservation and Recovery Act. 2543.16... OTHER NON-PROFIT ORGANIZATIONS Pre-Award Requirements § 2543.16 Resource Conservation and Recovery Act. Under the Act Resource Conservation and Recovery Act (42 U.S.C. 6962), any State agency or agency of...

  4. 45 CFR 2543.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Resource Conservation and Recovery Act. 2543.16... OTHER NON-PROFIT ORGANIZATIONS Pre-Award Requirements § 2543.16 Resource Conservation and Recovery Act. Under the Act Resource Conservation and Recovery Act (42 U.S.C. 6962), any State agency or agency of...

  5. 45 CFR 2543.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Resource Conservation and Recovery Act. 2543.16... OTHER NON-PROFIT ORGANIZATIONS Pre-Award Requirements § 2543.16 Resource Conservation and Recovery Act. Under the Act Resource Conservation and Recovery Act (42 U.S.C. 6962), any State agency or agency of...

  6. 45 CFR 2543.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Resource Conservation and Recovery Act. 2543.16... OTHER NON-PROFIT ORGANIZATIONS Pre-Award Requirements § 2543.16 Resource Conservation and Recovery Act. Under the Act Resource Conservation and Recovery Act (42 U.S.C. 6962), any State agency or agency of...

  7. 45 CFR 2543.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Resource Conservation and Recovery Act. 2543.16... OTHER NON-PROFIT ORGANIZATIONS Pre-Award Requirements § 2543.16 Resource Conservation and Recovery Act. Under the Act Resource Conservation and Recovery Act (42 U.S.C. 6962), any State agency or agency of...

  8. 78 FR 63877 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Infrastructure...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ...; Infrastructure Requirements for the 2010 Nitrogen Dioxide National Ambient Air Quality Standards AGENCY... elements of the Clean Air Act (CAA), necessary to implement, maintain, and enforce the 2010 nitrogen... Environmental protection, Air pollution control, Incorporation by reference, Nitrogen dioxide, Reporting...

  9. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT...) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Contracts (Appalachian Contracts) § 633.211 Implementation of the Clean Air Act and the Federal...

  10. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT...) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Contracts (Appalachian Contracts) § 633.211 Implementation of the Clean Air Act and the Federal...

  11. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT...) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Contracts (Appalachian Contracts) § 633.211 Implementation of the Clean Air Act and the Federal...

  12. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT...) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Contracts (Appalachian Contracts) § 633.211 Implementation of the Clean Air Act and the Federal...

  13. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT...) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Contracts (Appalachian Contracts) § 633.211 Implementation of the Clean Air Act and the Federal...

  14. Policy implications of genetic information on regulation under the Clean Air Act: the case of particulate matter and asthmatics.

    PubMed

    Kramer, C Bradley; Cullen, Alison C; Faustman, Elaine M

    2006-03-01

    The U.S. Clean Air Act (CAA) explicitly guarantees the protection of sensitive human subpopulations from adverse health effects associated with air pollution exposure. Identified subpopulations, such as asthmatics, may carry multiple genetic susceptibilities to disease onset and progression and thus qualify for special protection under the CAA. Scientific advances accelerated as a result of the groundbreaking Human Genome Project enable the quantification of genetic information that underlies such human variability in susceptibility and the cellular mechanisms of disease. In epidemiology and regulatory toxicology, genetic information can more clearly elucidate human susceptibility essential to risk assessment, such as in support of air quality regulation. In an effort to encourage the incorporation of genomic information in regulation, the U.S. Environmental Protection Agency (EPA) has issued an Interim Policy on Genomics. Additional research strategy and policy documents from the National Academy of Science, the U.S. EPA, and the U.S. Department of Health and Human Services further promote the expansion of asthma genetics research for human health risk assessment. Through a review of these government documents, we find opportunities for the inclusion of genetic information in the regulation of air pollutants. In addition, we identify sources of information in recent scientific research on asthma genetics relevant to regulatory standard setting. We conclude with recommendations on how to integrate these approaches for the improvement of regulatory health science and the prerequisites for inclusion of genetic information in decision making.

  15. 16 CFR 301.2 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.2 General requirements. (a) Each and every fur... with the requirements of the act and rules and regulations. (b) Each and every fur shall be invoiced in conformity with the requirements of the act and rules and regulations. (c) Any advertising of fur products...

  16. 16 CFR 301.2 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.2 General requirements. (a) Each and every fur... with the requirements of the act and rules and regulations. (b) Each and every fur shall be invoiced in conformity with the requirements of the act and rules and regulations. (c) Any advertising of fur products...

  17. 16 CFR 301.2 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.2 General requirements. (a) Each and every fur... with the requirements of the act and rules and regulations. (b) Each and every fur shall be invoiced in conformity with the requirements of the act and rules and regulations. (c) Any advertising of fur products...

  18. 16 CFR 301.2 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.2 General requirements. (a) Each and every fur... with the requirements of the act and rules and regulations. (b) Each and every fur shall be invoiced in conformity with the requirements of the act and rules and regulations. (c) Any advertising of fur products...

  19. 16 CFR 301.2 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.2 General requirements. (a) Each and every fur... with the requirements of the act and rules and regulations. (b) Each and every fur shall be invoiced in conformity with the requirements of the act and rules and regulations. (c) Any advertising of fur products...

  20. 49 CFR 19.16 - Resource Conservation and Recovery Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Resource Conservation and Recovery Act. 19.16 Section 19.16 Transportation Office of the Secretary of Transportation UNIFORM ADMINISTRATIVE REQUIREMENTS... ORGANIZATIONS Pre-Award Requirements § 19.16 Resource Conservation and Recovery Act. Under the Act, any...