Science.gov

Sample records for act ipa assignment

  1. Demand Assignment in the ACTS LBR System

    NASA Technical Reports Server (NTRS)

    White, Lawrence W.; Palmer, Larry C.

    1990-01-01

    On the Advanced Communications Technology Satellite (ACTS) being developed at NASA Lewis, low-burst-rate (LBR) traffic stations will access the ACTS multibeam package via two hopping beams that can be directed at certain areas in the continental U.S. An onboard baseband processor (BBP) demodulates uplink traffic, switches it between uplink and downlink beams at baseband, and then remodulates it for retransmission at 20 GHz. This study describes the demand-assigned operation of the ACTS LBR system, where the onboard switch is remote from both traffic stations and master control station (MCS). Network control uses inbound and outbound orderwire channels and a BBP control channel, allowing the MCS to coordinate assignment of individual 64-kb/s spacecraft channels. Models are developed to simulate the dynamics of the assignment process and verify the call blocking behavior, to predict control channel loads, and to evaluate algorithms for burst time plan rearrangement.

  2. The IPA appointment as a professional-development learning platform

    NASA Astrophysics Data System (ADS)

    Koepke, Mark

    2011-10-01

    Federal agencies make most of their Intergovernmental Personnel Act (IPA) mobility assignments with academia in order to bring personnel with specialized experience into the federal government. Federal detailing and non-federal contracting are also used as programmatic needs arise. In this poster, an IPA mobility assignment in the DOE Office of Fusion Energy Sciences (FES) is described that took place from August 2009 to August 2011. The title of the assignment was Senior Scientific Coordinator and the range of responsibility was extensive. The timing of the assignment coincided with significant personnel changes at the senior management level within DOE and this worked to the benefit of the strategic planning nature of the assignment. The implementation of the recommendations of the Physics 2010: Plasma Science NRC report will be outlined. The positive outcomes from the IPA experience will be put into the context of suggesting that university professors could find intellectual stimulation and professional reward, while serving the plasma physics community, by participating in an IPA. This work supported by the U.S. Dept. of Energy.

  3. IPAS Implementation Handbook

    ERIC Educational Resources Information Center

    Brooks, D. Christopher

    2014-01-01

    While the use of analytics to promote student success is gaining in popularity, basic questions about what IPAS is and the issues institutions face during implementation and integration. The "IPAS Implementation Handbook" catalogs the experiences, observations, and practical advice from 19 institutions engaged in IPAS implementation…

  4. 7 CFR 12.34 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12.34 Agriculture Office of the Secretary of Agriculture HIGHLY ERODIBLE LAND AND WETLAND CONSERVATION Wetland Conservation § 12.34 Paperwork Reduction Act assigned number. The information collection requirements contained in this regulation (7 CFR part 12) have been approved by the Office of Management...

  5. 7 CFR 12.34 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12.34 Agriculture Office of the Secretary of Agriculture HIGHLY ERODIBLE LAND AND WETLAND CONSERVATION Wetland Conservation § 12.34 Paperwork Reduction Act assigned number. The information collection requirements contained in this regulation (7 CFR part 12) have been approved by the Office of Management...

  6. 7 CFR 12.34 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12.34 Agriculture Office of the Secretary of Agriculture HIGHLY ERODIBLE LAND AND WETLAND CONSERVATION Wetland Conservation § 12.34 Paperwork Reduction Act assigned number. The information collection requirements contained in this regulation (7 CFR part 12) have been approved by the Office of Management...

  7. 7 CFR 12.34 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12.34 Agriculture Office of the Secretary of Agriculture HIGHLY ERODIBLE LAND AND WETLAND CONSERVATION Wetland Conservation § 12.34 Paperwork Reduction Act assigned number. The information collection requirements contained in this regulation (7 CFR part 12) have been approved by the Office of Management...

  8. 7 CFR 12.34 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12.34 Agriculture Office of the Secretary of Agriculture HIGHLY ERODIBLE LAND AND WETLAND CONSERVATION Wetland Conservation § 12.34 Paperwork Reduction Act assigned number. The information collection requirements contained in this regulation (7 CFR part 12) have been approved by the Office of Management...

  9. 7 CFR 1580.602 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Paperwork Reduction Act assigned number. 1580.602 Section 1580.602 Agriculture Regulations of the Department of Agriculture (Continued) FOREIGN AGRICULTURAL SERVICE, DEPARTMENT OF AGRICULTURE TRADE ADJUSTMENT ASSISTANCE FOR FARMERS § 1580.602 Paperwork...

  10. 7 CFR 1150.187 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Miscellaneous § 1150.187 Paperwork Reduction Act assigned number. The..., 1150.172, 1150.202, 1150.204, 1150.205, 1150.211 and 1150.273 of these regulations (7 CFR Part...

  11. 7 CFR 1150.187 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Miscellaneous § 1150.187 Paperwork Reduction Act assigned number. The..., 1150.172, and 1150.273 of these regulations (7 CFR part 1150) have been approved by the Office...

  12. 7 CFR 1150.187 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Miscellaneous § 1150.187 Paperwork Reduction Act assigned number. The..., 1150.172, and 1150.273 of these regulations (7 CFR part 1150) have been approved by the Office...

  13. 7 CFR 1150.187 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Miscellaneous § 1150.187 Paperwork Reduction Act assigned number. The..., 1150.172, and 1150.273 of these regulations (7 CFR part 1150) have been approved by the Office...

  14. 3 CFR - Assignment of Reporting Function Under the American Recovery and Reinvestment Act of 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... by the Constitution and the laws of the United States, including section 301 of title 3, United... 3 The President 1 2010-01-01 2010-01-01 false Assignment of Reporting Function Under the American... 15, 2009 Assignment of Reporting Function Under the American Recovery and Reinvestment Act......

  15. 46 CFR 167.01-20 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS General Provisions § 167.01-20 OMB control numbers assigned... of Management and Budget (OMB) pursuant to the Paperwork Reduction Act of 1980 (44 U.S.C. 3501 et seq... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  16. 27 CFR 19.1010 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false OMB control numbers... Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Paperwork Reduction Act § 19.1010 OMB control numbers assigned pursuant to the Paperwork...

  17. 46 CFR 540.91 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Reduction Act. 540.91 Section 540.91 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... that agencies display a current control number assigned by the Director of the Office of Management and Budget (OMB) for each agency information collection requirement: Section Current OMB Control No....

  18. 46 CFR 540.91 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Reduction Act. 540.91 Section 540.91 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... that agencies display a current control number assigned by the Director of the Office of Management and Budget (OMB) for each agency information collection requirement: Section Current OMB Control No....

  19. 46 CFR 540.91 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Reduction Act. 540.91 Section 540.91 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... that agencies display a current control number assigned by the Director of the Office of Management and Budget (OMB) for each agency information collection requirement: Section Current OMB Control No....

  20. 46 CFR 540.91 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Reduction Act. 540.91 Section 540.91 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... that agencies display a current control number assigned by the Director of the Office of Management and Budget (OMB) for each agency information collection requirement: Section Current OMB Control No....

  1. 46 CFR 540.91 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Reduction Act. 540.91 Section 540.91 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... that agencies display a current control number assigned by the Director of the Office of Management and Budget (OMB) for each agency information collection requirement: Section Current OMB Control No....

  2. 7 CFR 28.165 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... assigned to information collection requirements of the Office of Management and Budget contained in 7 CFR part 28 under the Paperwork Reduction Act of 1980. (b) Display. 7 CFR sections where identified and... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE...

  3. 46 CFR 401.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Reduction Act. 401.105 Section 401.105 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE REGULATIONS General § 401.105 OMB control numbers assigned pursuant to the... collection requirement. (b) Display. 46 CFR part of section where identified or described Current OMB...

  4. 7 CFR 28.165 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... assigned to information collection requirements of the Office of Management and Budget contained in 7 CFR part 28 under the Paperwork Reduction Act of 1980. (b) Display. 7 CFR sections where identified and... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE...

  5. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Director of OMB for each agency information collection requirement. (b) Display. 18 CFR part or section... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and...

  6. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Director of OMB for each agency information collection requirement. (b) Display. 18 CFR part or section... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and...

  7. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Director of OMB for each agency information collection requirement. (b) Display. 18 CFR part or section... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and...

  8. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Director of OMB for each agency information collection requirement. (b) Display. 18 CFR part or section... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and...

  9. 46 CFR 50.01-20 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 50.01-20 Section 50.01-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... for each approved agency information collection requirement. (b) Display. 46 CFR Part or Section...

  10. 46 CFR 25.01-5 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 25.01-5 Section 25.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY UNINSPECTED... requirement. (b) Display. 46 CFR part or section where identified or described Current OMB control No. §...

  11. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Management and Budget contained in 27 CFR Part 25 under the Paperwork Reduction Act of 1980, Pub. L. 96-511... sections in 27 CFR Part 25: §§ 25.23, 25.25, 25.52, 25.61, 25.62, 25.64, 25.66, 25.67, 25.68, 25.71, 25.72... control number 1512-0052. OMB control number 1512-0052 is assigned to the following sections in 27...

  12. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Management and Budget contained in 27 CFR Part 25 under the Paperwork Reduction Act of 1980, Pub. L. 96-511... sections in 27 CFR Part 25: §§ 25.23, 25.25, 25.52, 25.61, 25.62, 25.64, 25.66, 25.67, 25.68, 25.71, 25.72... control number 1512-0052. OMB control number 1512-0052 is assigned to the following sections in 27...

  13. 14 CFR 11.201 - Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROCEDURES Paperwork Reduction Act Control Numbers § 11.201 Office of Management and Budget (OMB) control... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act. 11.201 Section 11.201 Aeronautics and...

  14. 15 CFR 30.63 - Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... collection requirement. (b) Display. 15 CFR section whereidentified and described Current OMB control No... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act. 30.63 Section 30.63 Commerce and...

  15. 3 CFR - Assignment of Functions Under the National Defense Authorization Act for Fiscal Year 2010; the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Department of the Interior, Environment, and Related Agencies Appropriations Act, 2010 Presidential Documents..., 2010; and the Department of the Interior, Environment, and Related Agencies Appropriations Act, 2010... Department of the Interior, Environment, and Related Agencies Appropriations Act, 2010 (Public Law...

  16. 7 CFR 52.59 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1...

  17. 7 CFR 52.59 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1...

  18. Instructional Decision Making and IPAs: Assessing the Modes of Communication

    ERIC Educational Resources Information Center

    Kissau, Scott; Adams, Mary Jo

    2016-01-01

    Integrated Performance Assessments (IPAs) provide elementary, secondary, and postsecondary instructors with the opportunity to align standards-based foreign language instruction with assessment practices. While IPA guidelines make it clear that all three modes of communication are to be assessed, the limited body of research on IPAs provides few…

  19. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to... agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  20. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to... agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  1. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  2. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  3. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  4. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  5. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned... approved agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  6. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to... agency information collection requirement. (b) Display. 46 CFR part or section where identified...

  7. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or sectionwhere identified or...) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant...

  8. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or section where identified or...) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant...

  9. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or section where identified or...) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant...

  10. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or sectionwhere identified or...) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant...

  11. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or sectionwhere identified or...) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant...

  12. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or section where identified or...) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant...

  13. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... agency information collection requirement. (b) Display. 46 CFR part or section where identified or...) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant...

  14. The IPA--An Opportunity for Intergovernmental Understanding. Resource Paper No. 13.

    ERIC Educational Resources Information Center

    Anderson, Christine E.

    The Intergovernmental Personnel Act Program (IPA), begun in 1971, provides for the temporary exchange of personnel between federal executive agencies and states, local governments, institutions of higher education, and Indian tribal governments to do work of mutual benefit and concern. In the five years following the program's inception, more than…

  15. 7 CFR 52.59 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1 Regulations Governing Inspection and...

  16. 7 CFR 52.59 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1 Regulations Governing Inspection and...

  17. 7 CFR 1000.93 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Miscellaneous Provisions § 1000.93 OMB control number assigned... have been approved by the Office of Management and Budget (OMB) under the provisions of Title 44...

  18. 7 CFR 1000.93 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Miscellaneous Provisions § 1000.93 OMB control number assigned... have been approved by the Office of Management and Budget (OMB) under the provisions of Title 44...

  19. 7 CFR 1000.93 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Miscellaneous Provisions § 1000.93 OMB control number assigned... have been approved by the Office of Management and Budget (OMB) under the provisions of Title 44...

  20. 7 CFR 1000.93 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Miscellaneous Provisions § 1000.93 OMB control number assigned... have been approved by the Office of Management and Budget (OMB) under the provisions of Title 44...

  1. 46 CFR 535.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Reduction Act. 535.991 Section 535.991 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE... section 3507(a)(3) of the Paperwork Reduction Act, which requires that agencies display a current...

  2. 46 CFR 535.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Reduction Act. 535.991 Section 535.991 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE... section 3507(a)(3) of the Paperwork Reduction Act, which requires that agencies display a current...

  3. 46 CFR 535.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Reduction Act. 535.991 Section 535.991 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE... section 3507(a)(3) of the Paperwork Reduction Act, which requires that agencies display a current...

  4. 46 CFR 535.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Reduction Act. 535.991 Section 535.991 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE... section 3507(a)(3) of the Paperwork Reduction Act, which requires that agencies display a current...

  5. 46 CFR 535.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Reduction Act. 535.991 Section 535.991 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE... section 3507(a)(3) of the Paperwork Reduction Act, which requires that agencies display a current...

  6. 7 CFR 51.62 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT FRESH FRUITS... have been approved by the Office of Management and Budget (OMB) under the provisions of 44...

  7. Shigella IpaD has a dual role: signal transduction from the type III secretion system needle tip and intracellular secretion regulation.

    PubMed

    Roehrich, A Dorothea; Guillossou, Enora; Blocker, Ariel J; Martinez-Argudo, Isabel

    2013-02-01

    Type III secretion systems (T3SSs) are protein injection devices essential for the interaction of many Gram-negative bacteria with eukaryotic cells. While Shigella assembles its T3SS when the environmental conditions are appropriate for invasion, secretion is only activated after physical contact with a host cell. First, the translocators are secreted to form a pore in the host cell membrane, followed by effectors which manipulate the host cell. Secretion activation is tightly controlled by conserved T3SS components: the needle tip proteins IpaD and IpaB, the needle itself and the intracellular gatekeeper protein MxiC. To further characterize the role of IpaD during activation, we combined random mutagenesis with a genetic screen to identify ipaD mutant strains unable to respond to host cell contact. Class II mutants have an overall defect in secretion induction. They map to IpaD's C-terminal helix and likely affect activation signal generation or transmission. The Class I mutant secretes translocators prematurely and is specifically defective in IpaD secretion upon activation. A phenotypically equivalent mutant was found in mxiC. We show that IpaD and MxiC act in the same intracellular pathway. In summary, we demonstrate that IpaD has a dual role and acts at two distinct locations during secretion activation.

  8. 7 CFR 62.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INSPECTION ACT (CONTINUED) LIVESTOCK, MEAT, AND OTHER AGRICULTURAL COMMODITIES (QUALITY SYSTEMS VERIFICATION PROGRAMS) Quality Systems Verification Programs Definitions Miscellaneous § 62.400 OMB control number...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF...

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    Code of Federal Regulations, 2011 CFR

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    ... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905 through 998 under the Paperwork Reduction Act of 1995. (b) Display. 7 CFR part where identified and...-0149 922, Washington Apricots 0581-0095 923, Washington Sweet Cherries 0581-0133 924,...

  10. 7 CFR 900.601 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905 through 998 under the Paperwork Reduction Act of 1995. (b) Display. 7 CFR part where identified and...-0149 922, Washington Apricots 0581-0095 923, Washington Sweet Cherries 0581-0133 924,...

  11. 7 CFR 900.601 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

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    ... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905 through 998 under the Paperwork Reduction Act of 1995. (b) Display. 7 CFR part where identified and...-0149 922, Washington Apricots 0581-0095 923, Washington Sweet Cherries 0581-0133 924,...

  12. 7 CFR 900.601 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

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    ... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905 through 998 under the Paperwork Reduction Act of 1995. (b) Display. 7 CFR part where identified and...-0149 922, Washington Apricots 0581-0095 923, Washington Sweet Cherries 0581-0133 924,...

  13. 7 CFR 58.100 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

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    ... FOR GRADES OF DAIRY PRODUCTS 1 General Specifications for Dairy Plants Approved for USDA Inspection... 7 CFR part 58, subpart B, by the Office of Management and Budget pursuant to the Paperwork Reduction Act of 1980, Pub. L. 96-511. 7 CFR section where requirements are described Current OMB control No....

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    Code of Federal Regulations, 2011 CFR

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    ... collection requirements by the Office of Management and Budget contained in 7 CFR part 1250 pursuant to the Paperwork Reduction Act of 1980, Pub. L. 96-511. (b) Display. 7 CFR section where identified and described... (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS...

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    Code of Federal Regulations, 2013 CFR

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    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... requirements in 7 CFR part 58, subpart A, by the Office of Management and Budget pursuant to the...

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    Code of Federal Regulations, 2013 CFR

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    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... collection requirements in 7 CFR part 54, subpart C, by the Office of Management and Budget pursuant to...

  17. 76 FR 43729 - Notice of Random Assignment Study To Evaluate Workforce Investment Act Adult and Dislocated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... Adult and Dislocated Worker Programs; Request for Comment AGENCY: Employment and Training Administration... intensive services and training provided under the Workforce Investment Act (WIA) Adult and Dislocated... WIA Adult and Dislocated Worker programs will be required to participate in the study during a...

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    ... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905 through 998 under the Paperwork Reduction Act of 1995. (b) Display. 7 CFR part where identified and..., California Nectarines 0581-0072 917, California Pears and Peaches 0581-0080 920, California Kiwifruit...

  19. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

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    ... ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations... Management and Budget contained in 27 CFR Part 25 under the Paperwork Reduction Act of 1980, Pub. L. 96-511... sections in 27 CFR Part 25: §§ 25.23, 25.25, 25.52, 25.61, 25.62, 25.64, 25.66, 25.67, 25.68, 25.71,...

  20. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

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  1. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

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    ... ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Scope of Regulations... Management and Budget contained in 27 CFR Part 25 under the Paperwork Reduction Act of 1980, Pub. L. 96-511... sections in 27 CFR Part 25: §§ 25.23, 25.25, 25.52, 25.61, 25.62, 25.64, 25.66, 25.67, 25.68, 25.71,...

  2. 9 CFR 590.18 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

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    Code of Federal Regulations, 2014 CFR

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  5. How HMOs assess medical groups and IPAs.

    PubMed

    Penner, M

    1997-01-01

    California health maintenance organizations (HMOs) frequently capitate physician organizations--independent practice associations (IPAs) and multispecialty medical groups--to export their risk for professional and outpatient ancillary services. Physician organizations benefit when successful in managing the risk, and from having greater control over medical management decisions. HMOs carefully assess the physician organization's ability to manage capitated risk and provide high-quality care. HMOs gather information on the physician organization's finances, business relationships, physician compensation arrangements, credentialing, hospital relationships, ancillary contracts, procedures for 24-hour care, claims administration, member services, information systems for reporting and tracking utilization, and procedures for utilization/quality management. These data are analyzed to determine whether capitation contract negotiation should proceed. PMID:10166982

  6. Drafting and acting on feedback supports student learning when writing essay assignments.

    PubMed

    Freestone, Nicholas

    2009-06-01

    A diverse student population is a relatively recent feature of the higher education system in the United Kingdom. Consequently, it may be thought that more "traditional" types of assessment based around essay writing skills for science undergraduates may be of decreasing value and relevance to contemporary students. This article describes a study in which the process of feedback on, and associated redrafting of, an essay was closely supervised to improve essay writing skills and subsequent exam performance. The results of this study show that students can significantly improve their learning and academic performance, as assessed by final examination mark, by a process that more closely mimics a "real-world" situation of review and redrafting. Additionally, the data show that students benefit from feedback only when this is used appropriately by the student. The article also discusses the continuing importance and relevance of essay writing skills so that writing, and acting upon feedback to do with that writing, remains an integral part of the process of learning.

  7. 2. EAST ELEVATION OF IPA FACTORY; TWOSTORY SECTION BUILT IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. EAST ELEVATION OF IPA FACTORY; TWO-STORY SECTION BUILT IN 1892 AND PARTIALLY DESTROYED PARAPET SECTION BUILT CA. 1948. BRICK CHIMNEY ALSO BUILT CA. 1948. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  8. 3 CFR - Assignment of Function Under Section 601 of the American Recovery and Reinvestment Act of 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... me as President by the Constitution and the laws of the United States, including section 301 of title 3, United States Code, I hereby assign to you the function of the President under section 601, title... 3 The President 1 2010-01-01 2010-01-01 false Assignment of Function Under Section......

  9. Macrophage Apoptosis Triggered by IpaD from Shigella flexneri.

    PubMed

    Arizmendi, Olivia; Picking, William D; Picking, Wendy L

    2016-06-01

    Shigellosis, a potentially severe bacillary dysentery, is an infectious gastrointestinal disease caused by Shigella spp. Shigella invades the human colonic epithelium and avoids clearance by promoting apoptosis of resident immune cells in the gut. This process is dependent on the Shigella type III secretion system (T3SS), which injects effector proteins into target cells to alter their normal cellular functions. Invasion plasmid antigen D (IpaD) is a structural component that forms a complex at the tip of the T3SS apparatus needle. Recently, IpaD has also been shown to indirectly induce apoptosis in B lymphocytes. In this study, we explored the cytotoxicity profile during macrophage infection by Shigella and discovered that the pathogen induces macrophage cell death independent of caspase-1. Our results demonstrate that IpaD triggers apoptosis in macrophages through activation of host caspases accompanied by mitochondrial disruption. Additionally, we found that the IpaD N-terminal domain is necessary for macrophage killing and SipD, a structural homologue from Salmonella, was found to promote similar cytotoxicity. Together, these findings indicate that IpaD is a contributing factor to macrophage cell death during Shigella infection. PMID:27068089

  10. Macrophage Apoptosis Triggered by IpaD from Shigella flexneri.

    PubMed

    Arizmendi, Olivia; Picking, William D; Picking, Wendy L

    2016-06-01

    Shigellosis, a potentially severe bacillary dysentery, is an infectious gastrointestinal disease caused by Shigella spp. Shigella invades the human colonic epithelium and avoids clearance by promoting apoptosis of resident immune cells in the gut. This process is dependent on the Shigella type III secretion system (T3SS), which injects effector proteins into target cells to alter their normal cellular functions. Invasion plasmid antigen D (IpaD) is a structural component that forms a complex at the tip of the T3SS apparatus needle. Recently, IpaD has also been shown to indirectly induce apoptosis in B lymphocytes. In this study, we explored the cytotoxicity profile during macrophage infection by Shigella and discovered that the pathogen induces macrophage cell death independent of caspase-1. Our results demonstrate that IpaD triggers apoptosis in macrophages through activation of host caspases accompanied by mitochondrial disruption. Additionally, we found that the IpaD N-terminal domain is necessary for macrophage killing and SipD, a structural homologue from Salmonella, was found to promote similar cytotoxicity. Together, these findings indicate that IpaD is a contributing factor to macrophage cell death during Shigella infection.

  11. Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice.

    PubMed

    Heine, Shannon J; Franco-Mahecha, Olga L; Chen, Xiaotong; Choudhari, Shyamal; Blackwelder, William C; van Roosmalen, Maarten L; Leenhouts, Kees; Picking, Wendy L; Pasetti, Marcela F

    2015-08-01

    Shigella spp. are among the enteric pathogens with the highest attributable incidence of moderate-to-severe diarrhea in children under 5 years of age living in endemic areas. There are no vaccines available to prevent this disease. In this work, we investigated a new Shigella vaccine concept consisting of nonliving, self-adjuvanted, Lactococcus lactis bacterium-like particles (BLP) displaying Shigella invasion plasmid antigen (Ipa) B and IpaD and examined its immunogenicity and protective efficacy in adult and newborn/infant mice immunized via the nasal route. Unique advantages of this approach include the potential for broad protection due to the highly conserved structure of the Ipas and the safety and practicality of a probiotic-based mucosal/adjuvant delivery platform. Immunization of adult mice with BLP-IpaB and BLP-IpaD (BLP-IpaB/D) induced high levels of Ipa-specific serum IgG and stool IgA in a dose-dependent manner. Immune responses and protection were enhanced by BLP delivery. Vaccine-induced serum antibodies exhibited opsonophagocytic and cytotoxic neutralizing activity, and IpaB/D IgG titers correlated with increased survival post-challenge. Ipa-specific antibody secreting cells were detected in nasal tissue and lungs, as well as IgG in bronchoalveolar lavage. Bone marrow cells produced IpaB/D-specific antibodies and contributed to protection after adoptive transfer. The BLP-IpaB/D vaccine conferred 90% and 80% protection against S. flexneri and S. sonnei, respectively. Mice immunized with BLP-IpaB/D as newborns also developed IpaB and IpaD serum antibodies; 90% were protected against S. flexneri and 44% against S. sonnei. The BLP-IpaB/D vaccine is a promising candidate for safe, practical and potentially effective immunization of children against shigellosis.

  12. Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice.

    PubMed

    Heine, Shannon J; Franco-Mahecha, Olga L; Chen, Xiaotong; Choudhari, Shyamal; Blackwelder, William C; van Roosmalen, Maarten L; Leenhouts, Kees; Picking, Wendy L; Pasetti, Marcela F

    2015-08-01

    Shigella spp. are among the enteric pathogens with the highest attributable incidence of moderate-to-severe diarrhea in children under 5 years of age living in endemic areas. There are no vaccines available to prevent this disease. In this work, we investigated a new Shigella vaccine concept consisting of nonliving, self-adjuvanted, Lactococcus lactis bacterium-like particles (BLP) displaying Shigella invasion plasmid antigen (Ipa) B and IpaD and examined its immunogenicity and protective efficacy in adult and newborn/infant mice immunized via the nasal route. Unique advantages of this approach include the potential for broad protection due to the highly conserved structure of the Ipas and the safety and practicality of a probiotic-based mucosal/adjuvant delivery platform. Immunization of adult mice with BLP-IpaB and BLP-IpaD (BLP-IpaB/D) induced high levels of Ipa-specific serum IgG and stool IgA in a dose-dependent manner. Immune responses and protection were enhanced by BLP delivery. Vaccine-induced serum antibodies exhibited opsonophagocytic and cytotoxic neutralizing activity, and IpaB/D IgG titers correlated with increased survival post-challenge. Ipa-specific antibody secreting cells were detected in nasal tissue and lungs, as well as IgG in bronchoalveolar lavage. Bone marrow cells produced IpaB/D-specific antibodies and contributed to protection after adoptive transfer. The BLP-IpaB/D vaccine conferred 90% and 80% protection against S. flexneri and S. sonnei, respectively. Mice immunized with BLP-IpaB/D as newborns also developed IpaB and IpaD serum antibodies; 90% were protected against S. flexneri and 44% against S. sonnei. The BLP-IpaB/D vaccine is a promising candidate for safe, practical and potentially effective immunization of children against shigellosis. PMID:25776843

  13. 1. SOUTH AND WEST ELEVATION OF ILLINOIS PURE ALUMINUM (IPA) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. SOUTH AND WEST ELEVATION OF ILLINOIS PURE ALUMINUM (IPA) COMPANY FACTORY; SOUTH ELEVATION FACING ILLINOIS CENTRAL GULF RAILROAD TRACKS AND MAIN STREET. THE ONE-STORY BRICK BUILDING TO THE LEFT IS AN ABANDONED COMMONWEALTH EDISON COMPANY ELECTRICAL SUBSTATION. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  14. 3. SOUTH AND WEST ELEVATION OF IPA FACTORY; TWOSTORY SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. SOUTH AND WEST ELEVATION OF IPA FACTORY; TWO-STORY SECTION WITH BRICK PARAPET BUILT WITH FACTORY EXPANSION CA. 1948. GABLE ROOF SECTION IS PART OF ORIGINAL 1892 FACTORY. TO THE RIGHT IS AN ABANDONED (COMMONWEALTH EDISON) ELECTRICAL SUBSTATION. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

  15. An IPA-Embedded Model for Evaluating Creativity Curricula

    ERIC Educational Resources Information Center

    Chang, Chi-Cheng

    2014-01-01

    How to diagnose the effectiveness of creativity-related curricula is a crucial concern in the pursuit of educational excellence. This paper introduces an importance-performance analysis (IPA)-embedded model for curriculum evaluation, using the example of an IT project implementation course to assess the creativity performance deduced from student…

  16. N-terminus of IpaB provides a potential anchor to the Shigella type III secretion system tip complex protein IpaD.

    PubMed

    Dickenson, Nicholas E; Arizmendi, Olivia; Patil, Mrinalini K; Toth, Ronald T; Middaugh, C Russell; Picking, William D; Picking, Wendy L

    2013-12-10

    The type III secretion system (T3SS) is an essential virulence factor for Shigella flexneri , providing a conduit through which host-altering effectors are injected directly into a host cell to promote uptake. The type III secretion apparatus (T3SA) is composed of a basal body, external needle, and regulatory tip complex. The nascent needle is a polymer of MxiH capped by a pentamer of invasion plasmid antigen D (IpaD). Exposure to bile salts (e.g., deoxycholate) causes a conformational change in IpaD and promotes recruitment of IpaB to the needle tip. It has been proposed that IpaB senses contact with host cell membranes, recruiting IpaC and inducing full secretion of T3SS effectors. Although the steps of T3SA maturation and their external triggers have been identified, details of specific protein interactions and mechanisms have remained difficult to study because of the hydrophobic nature of the IpaB and IpaC translocator proteins. Here, we explored the ability for a series of soluble N-terminal IpaB peptides to interact with IpaD. We found that DOC is required for the interaction and that a region of IpaB between residues 11-27 is required for maximum binding, which was confirmed in vivo. Furthermore, intramolecular FRET measurements indicated that movement of the IpaD distal domain away from the protein core accompanied the binding of IpaB11-226. Together, these new findings provide important new insight into the interactions and potential mechanisms that define the maturation of the Shigella T3SA needle tip complex and provide a foundation for further studies probing T3SS activation.

  17. Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD.

    PubMed

    Heine, Shannon J; Diaz-McNair, Jovita; Martinez-Becerra, Francisco J; Choudhari, Shyamal P; Clements, John D; Picking, Wendy L; Pasetti, Marcela F

    2013-06-19

    Shigella spp. are food- and water-borne pathogens that cause shigellosis, a severe diarrheal and dysenteric disease that is associated with a high morbidity and mortality in resource-poor countries. No licensed vaccine is available to prevent shigellosis. We have recently demonstrated that Shigella invasion plasmid antigens (Ipas), IpaB and IpaD, which are components of the bacterial type III secretion system (TTSS), can prevent infection in a mouse model of intranasal immunization and lethal pulmonary challenge. Because they are conserved across Shigella spp. and highly immunogenic, these proteins are excellent candidates for a cross-protective vaccine. Ideally, such a vaccine could be administered to humans orally to induce mucosal and systemic immunity. In this study, we investigated the immunogenicity and protective efficacy of Shigella IpaB and IpaD administered orally with a double mutant of the Escherichia coli heat labile toxin (dmLT) as a mucosal adjuvant. We characterized the immune responses induced by oral vs. intranasal immunization and the protective efficacy using a mouse pulmonary infection model. Serum IgG and fecal IgA against IpaB were induced after oral immunization. These responses, however, were lower than those obtained after intranasal immunization despite a 100-fold dosage increase. The level of protection induced by oral immunization with IpaB and IpaD was 40%, while intranasal immunization resulted in 90% protective efficacy. IpaB- and IpaD-specific IgA antibody-secreting cells in the lungs and spleen and T-cell-derived IL-2, IL-5, IL-17 and IL-10 were associated with protection. These results demonstrate the immunogenicity of orally administered IpaB and IpaD and support further studies in humans.

  18. Novel Vinculin Binding Site of the IpaA Invasin of Shigella*♦

    PubMed Central

    Park, HaJeung; Valencia-Gallardo, Cesar; Sharff, Andrew; Van Nhieu, Guy Tran; Izard, Tina

    2011-01-01

    Internalization of Shigella into host epithelial cells, where the bacteria replicates and spreads to neighboring cells, requires a type 3 secretion system (T3SS) effector coined IpaA. IpaA binds directly to and activates the cytoskeletal protein vinculin after injection in the host cell cytosol, and this was previously thought to be directed by two amphipathic α-helical vinculin-binding sites (VBS) found in the C-terminal tail domain of IpaA. Here, we report a third VBS, IpaA-VBS3, that is located N-terminal to the other two VBSs of IpaA and show that one IpaA molecule can bind up to three vinculin molecules. Biochemical in vitro Shigella invasion assays and the 1.6 Å crystal structure of the vinculin·IpaA-VBS3 complex showed that IpaA-VBS3 is functionally redundant with the other two IpaA-VBSs in cell invasion and in activating the latent F-actin binding functions of vinculin. Multiple VBSs in IpaA are reminiscent of talin, which harbors 11 VBSs. However, most of the talin VBSs have low affinity and are buried in helix bundles, whereas all three of the VBSs of IpaA are high affinity, readily available, and in close proximity to each other in the IpaA structure. Although deletion of IpaA-VBS3 has no detectable effects on Shigella invasion of epithelial cells, deletion of all three VBSs impaired bacterial invasion to levels found in an ipaA null mutant strain. Thus, IpaA-directed mimicry of talin in activating vinculin occurs through three high affinity VBSs that are essential for Shigella pathogenesis. PMID:21525010

  19. Novel Vinculin Binding Site of the IpaA Invasin of Shigella

    SciTech Connect

    Park, HaJeung; Valencia-Gallardo, Cesar; Sharff, Andrew; Van Nhieu, Guy Tran; Izard, Tina

    2012-10-25

    Internalization of Shigella into host epithelial cells, where the bacteria replicates and spreads to neighboring cells, requires a type 3 secretion system (T3SS) effector coined IpaA. IpaA binds directly to and activates the cytoskeletal protein vinculin after injection in the host cell cytosol, and this was previously thought to be directed by two amphipathic {alpha}-helical vinculin-binding sites (VBS) found in the C-terminal tail domain of IpaA. Here, we report a third VBS, IpaA-VBS3, that is located N-terminal to the other two VBSs of IpaA and show that one IpaA molecule can bind up to three vinculin molecules. Biochemical in vitro Shigella invasion assays and the 1.6 {angstrom} crystal structure of the vinculin {center_dot} IpaA-VBS3 complex showed that IpaA-VBS3 is functionally redundant with the other two IpaA-VBSs in cell invasion and in activating the latent F-actin binding functions of vinculin. Multiple VBSs in IpaA are reminiscent of talin, which harbors 11 VBSs. However, most of the talin VBSs have low affinity and are buried in helix bundles, whereas all three of the VBSs of IpaA are high affinity, readily available, and in close proximity to each other in the IpaA structure. Although deletion of IpaA-VBS3 has no detectable effects on Shigella invasion of epithelial cells, deletion of all three VBSs impaired bacterial invasion to levels found in an ipaA null mutant strain. Thus, IpaA-directed mimicry of talin in activating vinculin occurs through three high affinity VBSs that are essential for Shigella pathogenesis.

  20. Characterization of a novel fusion protein from IpaB and IpaD of Shigella spp. and its potential as a pan-Shigella vaccine.

    PubMed

    Martinez-Becerra, Francisco J; Chen, Xiaotong; Dickenson, Nicholas E; Choudhari, Shyamal P; Harrison, Kelly; Clements, John D; Picking, William D; Van De Verg, Lillian L; Walker, Richard I; Picking, Wendy L

    2013-12-01

    Shigellosis is an important disease in the developing world, where about 90 million people become infected with Shigella spp. each year. We previously demonstrated that the type three secretion apparatus (T3SA) proteins IpaB and IpaD are protective antigens in the mouse lethal pulmonary model. In order to simplify vaccine formulation and process development, we have evaluated a vaccine design that incorporates both of these previously tested Shigella antigens into a single polypeptide chain. To determine if this fusion protein (DB fusion) retains the antigenic and protective capacities of IpaB and IpaD, we immunized mice with the DB fusion and compared the immune response to that elicited by the IpaB/IpaD combination vaccine. Purification of the DB fusion required coexpression with IpgC, the IpaB chaperone, and after purification it maintained the highly α-helical characteristics of IpaB and IpaD. The DB fusion also induced comparable immune responses and retained the ability to protect mice against Shigella flexneri and S. sonnei in the lethal pulmonary challenge. It also offered limited protection against S. dysenteriae challenge. Our results show the feasibility of generating a protective Shigella vaccine comprised of the DB fusion.

  1. Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip.

    PubMed

    Stensrud, Kenneth F; Adam, Philip R; La Mar, Cassandra D; Olive, Andrew J; Lushington, Gerald H; Sudharsan, Raghavi; Shelton, Naomi L; Givens, Richard S; Picking, Wendy L; Picking, William D

    2008-07-01

    Type III secretion (TTS) is an essential virulence function for Shigella flexneri that delivers effector proteins that are responsible for bacterial invasion of intestinal epithelial cells. The Shigella TTS apparatus (TTSA) consists of a basal body that spans the bacterial inner and outer membranes and a needle exposed at the pathogen surface. At the distal end of the needle is a "tip complex" composed of invasion plasmid antigen D (IpaD). IpaD not only regulates TTS, but is required for the recruitment and stable association of the translocator protein IpaB at the TTSA needle tip in the presence of deoxycholate or other bile salts. This phenomenon is not accompanied by induction of TTS or the recruitment of IpaC to the Shigella surface. We now show that IpaD specifically binds fluorescein-labeled deoxycholate and, based on energy transfer measurements and docking simulations, this interaction appears to occur where the N-terminal domain of IpaD meets its central coiled-coil, a region that may also be involved in needle-tip interactions. TTS is initiated as a series of distinct steps and that small molecules present in the bacterial milieu are capable of inducing the first step of TSS through interactions with the needle tip protein IpaD. Furthermore, the amino acids proposed to be important for deoxycholate binding by IpaD appear to have significant roles in regulating tip complex composition and pathogen entry into host cells.

  2. Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure.

    PubMed

    Barta, Michael L; Guragain, Manita; Adam, Philip; Dickenson, Nicholas E; Patil, Mrinalini; Geisbrecht, Brian V; Picking, Wendy L; Picking, William D

    2012-03-01

    Type III secretion (TTS) is an essential virulence factor for Shigella flexneri, the causative agent of shigellosis. The Shigella TTS apparatus (TTSA) is an elegant nanomachine that is composed of a basal body, an external needle to deliver effectors into human cells, and a needle tip complex that controls secretion activation. IpaD is at the tip of the nascent TTSA needle where it controls the first step of TTS activation. The bile salt deoxycholate (DOC) binds to IpaD to induce recruitment of the translocator protein IpaB into the maturing tip complex. We recently used spectroscopic analyses to show that IpaD undergoes a structural rearrangement that accompanies binding to DOC. Here, we report a crystal structure of IpaD with DOC bound and test the importance of the residues that make up the DOC binding pocket on IpaD function. IpaD binds DOC at the interface between helices α3 and α7, with concomitant movement in the orientation of helix α7 relative to its position in unbound IpaD. When the IpaD residues involved in DOC binding are mutated, some are found to lead to altered invasion and secretion phenotypes. These findings suggest that adoption of a DOC bound structural state for IpaD primes the Shigella TTSA for contact with host cells. The data presented here and in the studies leading up to this work provide the foundation for developing a model of the first step in Shigella TTS activation.

  3. Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure

    PubMed Central

    Barta, Michael L.; Guragain, Manita; Adam, Philip; Dickenson, Nicholas E.; Patil, Mrinalini; Geisbrecht, Brian V.; Picking, Wendy L.; Picking, William D.

    2011-01-01

    Type III secretion (TTS) is an essential virulence factor for Shigella flexneri, the causative agent of shigellosis. The Shigella TTS apparatus (TTSA) is an elegant nano-machine that is composed of a basal body, an external needle to deliver effectors into human cells, and a needle tip complex that controls secretion activation. IpaD is at the tip of the nascent TTSA needle where it controls the first step of TTS activation. The bile salt deoxycholate (DOC) binds to IpaD to induce recruitment of the translocator protein IpaB into the maturing tip complex. We recently used spectroscopic analyses to show that IpaD undergoes a structural rearrangement that accompanies binding to DOC. Here we report a crystal structure of IpaD with DOC bound and test the importance of the residues that make up the DOC binding pocket on IpaD function. IpaD binds DOC at the interface between helices α3 and α7, with concomitant movement in the orientation of helix α7 relative to its position in unbound IpaD. When the IpaD residues involved in DOC binding are mutated, some are found to lead to altered invasion and secretion phenotypes. These findings suggest that adoption of a DOC-bound structural state for IpaD primes the Shigella TTSA for contact with host cells. The data presented here and in the studies leading up to this work provide the foundation for developing a model of the first step in Shigella TTS activation. PMID:22423359

  4. Scalable and Cost-Effective Assignment of Mobile Crowdsensing Tasks Based on Profiling Trends and Prediction: The ParticipAct Living Lab Experience.

    PubMed

    Bellavista, Paolo; Corradi, Antonio; Foschini, Luca; Ianniello, Raffaele

    2015-01-01

    Nowadays, sensor-rich smartphones potentially enable the harvesting of huge amounts of valuable sensing data in urban environments, by opportunistically involving citizens to play the role of mobile virtual sensors to cover Smart City areas of interest. This paper proposes an in-depth study of the challenging technical issues related to the efficient assignment of Mobile Crowd Sensing (MCS) data collection tasks to volunteers in a crowdsensing campaign. In particular, the paper originally describes how to increase the effectiveness of the proposed sensing campaigns through the inclusion of several new facilities, including accurate participant selection algorithms able to profile and predict user mobility patterns, gaming techniques, and timely geo-notification. The reported results show the feasibility of exploiting profiling trends/prediction techniques from volunteers' behavior; moreover, they quantitatively compare different MCS task assignment strategies based on large-scale and real MCS data campaigns run in the ParticipAct living lab, an ongoing MCS real-world experiment that involved more than 170 students of the University of Bologna for more than one year. PMID:26263985

  5. Scalable and Cost-Effective Assignment of Mobile Crowdsensing Tasks Based on Profiling Trends and Prediction: The ParticipAct Living Lab Experience

    PubMed Central

    Bellavista, Paolo; Corradi, Antonio; Foschini, Luca; Ianniello, Raffaele

    2015-01-01

    Nowadays, sensor-rich smartphones potentially enable the harvesting of huge amounts of valuable sensing data in urban environments, by opportunistically involving citizens to play the role of mobile virtual sensors to cover Smart City areas of interest. This paper proposes an in-depth study of the challenging technical issues related to the efficient assignment of Mobile Crowd Sensing (MCS) data collection tasks to volunteers in a crowdsensing campaign. In particular, the paper originally describes how to increase the effectiveness of the proposed sensing campaigns through the inclusion of several new facilities, including accurate participant selection algorithms able to profile and predict user mobility patterns, gaming techniques, and timely geo-notification. The reported results show the feasibility of exploiting profiling trends/prediction techniques from volunteers’ behavior; moreover, they quantitatively compare different MCS task assignment strategies based on large-scale and real MCS data campaigns run in the ParticipAct living lab, an ongoing MCS real-world experiment that involved more than 170 students of the University of Bologna for more than one year. PMID:26263985

  6. Scalable and Cost-Effective Assignment of Mobile Crowdsensing Tasks Based on Profiling Trends and Prediction: The ParticipAct Living Lab Experience.

    PubMed

    Bellavista, Paolo; Corradi, Antonio; Foschini, Luca; Ianniello, Raffaele

    2015-07-30

    Nowadays, sensor-rich smartphones potentially enable the harvesting of huge amounts of valuable sensing data in urban environments, by opportunistically involving citizens to play the role of mobile virtual sensors to cover Smart City areas of interest. This paper proposes an in-depth study of the challenging technical issues related to the efficient assignment of Mobile Crowd Sensing (MCS) data collection tasks to volunteers in a crowdsensing campaign. In particular, the paper originally describes how to increase the effectiveness of the proposed sensing campaigns through the inclusion of several new facilities, including accurate participant selection algorithms able to profile and predict user mobility patterns, gaming techniques, and timely geo-notification. The reported results show the feasibility of exploiting profiling trends/prediction techniques from volunteers' behavior; moreover, they quantitatively compare different MCS task assignment strategies based on large-scale and real MCS data campaigns run in the ParticipAct living lab, an ongoing MCS real-world experiment that involved more than 170 students of the University of Bologna for more than one year.

  7. Convergent Evolution in the Assembly of Polyubiquitin Degradation Signals by the Shigella flexneri IpaH9.8 Ligase*

    PubMed Central

    Edwards, Daniel J.; Streich, Frederick C.; Ronchi, Virginia P.; Todaro, Dustin R.; Haas, Arthur L.

    2014-01-01

    The human pathogen Shigella flexneri subverts host function and defenses by deploying a cohort of effector proteins via a type III secretion system. The IpaH family of 10 such effectors mimics ubiquitin ligases but bears no sequence or structural homology to their eukaryotic counterpoints. Using rates of 125I-polyubiquitin chain formation as a functional read out, IpaH9.8 displays V-type positive cooperativity with respect to varying concentrations of its Ubc5B∼125I-ubiquitin thioester co-substrate in the nanomolar range ([S]½ = 140 ± 32 nm; n = 1.8 ± 0.1) and cooperative substrate inhibition at micromolar concentrations ([S]½ = 740 ± 240 nm; n = 1.7 ± 0.2), requiring ordered binding to two functionally distinct sites per subunit. The isosteric substrate analog Ubc5BC85S-ubiquitin oxyester acts as a competitive inhibitor of wild-type Ubc5B∼125I-ubiquitin thioester (Ki = 117 ± 29 nm), whereas a Ubc5BC85A product analog shows noncompetitive inhibition (Ki = 2.2 ± 0.5 μm), consistent with the two-site model. Re-evaluation of a related IpaH3 crystal structure (PDB entry 3CVR) identifies a symmetric dimer consistent with the observed cooperativity. Genetic disruption of the predicted IpaH9.8 dimer interface reduces the solution molecular weight and significantly ablates the kcat but not [S]½ for polyubiquitin chain formation. Other studies demonstrate that cooperativity requires the N-terminal leucine-rich repeat-targeting domain and is transduced through Phe395. Additionally, these mechanistic features are conserved in a distantly related SspH2 Salmonella enterica ligase. Kinetic parallels between IpaH9.8 and the recently revised mechanism for E6AP/UBE3A (Ronchi, V. P., Klein, J. M., and Haas, A. L. (2013) E6AP/UBE3A ubiquitin ligase harbors two E2∼ubiquitin binding sites. J. Biol. Chem. 288, 10349–10360) suggest convergent evolution of the catalytic mechanisms for prokaryotic and eukaryotic ligases. PMID:25342744

  8. Single amino acid substitutions on the needle tip protein IpaD increased Shigella virulence.

    PubMed

    Meghraoui, Alaeddine; Schiavolin, Lionel; Allaoui, Abdelmounaaïm

    2014-07-01

    Infection of colonic epithelial cells by Shigella is associated with the type III secretion system, which serves as a molecular syringe to inject effectors into host cells. This system includes an extracellular needle used as a conduit for secreted proteins. Two of these proteins, IpaB and IpaD, dock at the needle tip to control secretion and are also involved in the insertion of a translocation pore into host cell membrane allowing effector delivery. To better understand the function of IpaD, we substituted thirteen residues conserved among homologous proteins in other bacterial species. Generated variants were tested for their ability to surface expose IpaB and IpaD, to control secretion, to insert the translocation pore, and to invade host cells. In addition to a first group of seven ipaD variants that behaved similarly to the wild-type strain, we identified a second group with mutations V314D and I319D that deregulated secretion of all effectors, but remained fully invasive. Moreover, we identified a third group with mutations Y153A, T161D, Q165L and Y276A, that exhibited increased levels of translocators secretion, pore formation, and cell entry. Altogether, our results offer a better understanding of the role of IpaD in the control of Shigella virulence.

  9. Nondestructive Induced Residual Stress Assessment in Superalloy Turbine Engine Components Using Induced Positron Annihilation (IPA)

    SciTech Connect

    Rideout, C. A.; Ritchie, S. J.; Denison, A.

    2007-03-21

    Induced Positron Analysis (IPA) has demonstrated the ability to nondestructively quantify shot peening/surface treatments and relaxation effects in single crystal superalloys, steels, titanium and aluminum with a single measurement as part of a National Science Foundation SBIR program and in projects with commercial companies. IPA measurement of surface treatment effects provides a demonstrated ability to quantitatively measure initial treatment effectiveness along with the effect of operationally induced changes over the life of the treated component. Use of IPA to nondestructively quantify surface and subsurface residual stresses in turbine engine materials and components will lead to improvements in current engineering designs and maintenance procedures.

  10. The IPA and the American Psychoanalytic Association: a perspective on the regional association agreement.

    PubMed

    Wallerstein, R S

    1998-06-01

    Ever since 1938 the American Psychoanalytic Association has had a special autonomous relationship within the IPA accorded to no other component organisation. This Regional Association status has had two main features: (1) total internal control over training standards and membership criteria, with no accountability to the IPA; and (2) an 'exclusive franchise', so that the IPA was barred from recognising any other component within the United States. This unique Regional Association status reflected the resolution at the time (1938) of the long-standing controversy between the IPA and the American over the issue of 'lay analysis', and remained unaltered for half a century until, with the resolution of the 3 1/2-year long law-suit against the American (and secondarily against the IPA) in 1988, the Regional Association agreement was modified (but not totally abrogated) by the American's giving up the 'exclusive franchise' aspect (thus permitting IPA recognition of psychoanalytic groups in the US organised outside the American), but still retaining its internal full control over training and membership. The meanings and consequences for psychoanalysis of this special status of the American are explored.

  11. Self-Chaperoning of the Type III Secretion System needle tip proteins IpaD and BipD

    PubMed Central

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Olive, Andrew; Deane, Janet E.; Birket, Susan; Field, Terry; Picking, William D.; Blocker, Ariel; Galyov, Edouard E.; Picking, Wendy L.; Lea, Susan M.

    2007-01-01

    Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths of millions worldwide, acting as key virulence elements in diseases ranging from plague to typhoid fever. The T3SS is composed of a basal body, which traverses both bacterial membranes, and an external needle through which effector proteins are secreted. We report multiple crystal structures of two proteins that sit at the tip of the needle and are essential for virulence; IpaD from Shigella flexneri and BipD from Burkholderia pseudomallei. The structures reveal that the N-terminal domains of the molecules are intra-molecular chaperones that prevent premature oligomerization, as well as sharing structural homology with proteins involved in eukaryotic actin rearrangement. Crystal packing has allowed us to construct a model for the tip complex that is supported by mutations designed using the structure. PMID:17077085

  12. Bile salts stimulate recruitment of IpaB to the Shigella flexneri surface, where it colocalizes with IpaD at the tip of the type III secretion needle.

    PubMed

    Olive, Andrew J; Kenjale, Roma; Espina, Marianela; Moore, David S; Picking, Wendy L; Picking, William D

    2007-05-01

    Shigella flexneri uses its type III secretion apparatus (TTSA) to deliver invasins into human cells. This TTSA possesses an external needle with IpaD at its tip. We now show that deoxycholate promotes the stable recruitment of IpaB to the needle tip without inducing a rapid burst of type III secretion. The maintenance of IpaB at the needle tip requires a stable association of IpaD with the Shigella surface. This is the first demonstration of a translocator protein being stably associated with the TTSA needle.

  13. Molecular cloning and biologically active production of IpaD N-terminal region.

    PubMed

    Hesaraki, Mahdi; Saadati, Mojtaba; Honari, Hossein; Olad, Gholamreza; Heiat, Mohammad; Malaei, Fatemeh; Ranjbar, Reza

    2013-07-01

    Shigella is known as pathogenic intestinal bacteria in high dispersion and pathogenic bacteria due to invasive plasmid antigen (Ipa). So far, a number of Ipa proteins have been studied to introduce a new candidate vaccine. Here, for the first time, we examined whether the N-terminal region of IpaD(72-162) could be a proper candidate for Shigella vaccine. Initially, the DNA sequence coding N-terminal region was isolated by PCR from Shigella dysenteriae type I and cloned into pET-28a expression vector. Then, the heterologous protein was expressed, optimized and purified by affinity Ni-NTA column. Western blot analysis using, His-tag and IpaD(72-162) polyclonal antibodies, confirmed the purity and specificity of the recombinant protein, respectively. Subsequently, the high immunogenicity of the antigen was shown by ELISA. The results of the sereny test in Guinea pigs showed that IpaD(72-162) provides a protective system against Shigella flexneri 5a and S. dysenteriae type I.

  14. Space Data Systems Applications in the iPAS Pathfinder Laboratory

    NASA Technical Reports Server (NTRS)

    Rich, Tom

    2013-01-01

    The iPAS is an integrated hardware/software test and evaluation environment, in support of current and future spacecraft development The iPAS has two main elements. A common avionics, hardware, and software architecture that can be applied over various missions. A common testbed framework that supports integrated hardware/software testing for a variety of applications. The iPAS includes the following (non-flight qualified) components: Core Flight Software (from GSFC). Commercially available Proton and S950 Flight Computer boards. Power and propulsion systems based on representative flight hardware. A realistic flight deck based on the Multi-Purpose Crew Vehicle (MPCV), including realistic flight controls and displays. A Space Data System based on CCSDS protocols.

  15. 32 CFR 37.660 - What else must I specify concerning audits of for-profit participants by IPAs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false What else must I specify concerning audits of....660 What else must I specify concerning audits of for-profit participants by IPAs? If your expenditure-based TIA provides for audits of a for-profit participant by an IPA, you also must specify: (a)...

  16. 32 CFR 37.660 - What else must I specify concerning audits of for-profit participants by IPAs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false What else must I specify concerning audits of....660 What else must I specify concerning audits of for-profit participants by IPAs? If your expenditure-based TIA provides for audits of a for-profit participant by an IPA, you also must specify: (a)...

  17. MxiA, MxiC and IpaD Regulate Substrate Selection and Secretion Mode in the T3SS of Shigella flexneri

    PubMed Central

    Shen, Da-Kang; Blocker, Ariel J.

    2016-01-01

    Type III secretion systems (T3SSs) are central virulence devices for many Gram-negative bacterial pathogens of humans, animals & plants. Upon physical contact with eukaryotic host cells, they translocate virulence-mediating proteins, known as effectors, into them during infection. T3SSs are gated from the outside by host-cell contact and from the inside via two cytoplasmic negative regulators, MxiC and IpaD in Shigella flexneri, which together control the effector secretion hierarchy. Their absence leads to premature and increased secretion of effectors. Here, we investigated where and how these regulators act. We demonstrate that the T3SS inner membrane export apparatus protein MxiA plays a role in substrate selection. Indeed, using a genetic screen, we identified two amino acids located on the surface of MxiA’s cytoplasmic region (MxiAC) which, when mutated, upregulate late effector expression and, in the case of MxiAI674V, also secretion. The cytoplasmic region of MxiA, but not MxiAN373D and MxiAI674V, interacts directly with the C-terminus of MxiC in a two-hybrid assay. Efficient T3S requires a cytoplasmic ATPase and the proton motive force (PMF), which is composed of the ΔΨ and the ΔpH. MxiA family proteins and their regulators are implicated in utilization of the PMF for protein export. However, our MxiA point mutants show similar PMF utilisation to wild-type, requiring primarily the ΔΨ. On the other hand, lack of MxiC or IpaD, renders the faster T3S seen increasingly dependent on the ΔpH. Therefore, MxiA, MxiC and IpaD act together to regulate substrate selection and secretion mode in the T3SS of Shigella flexneri. PMID:27171191

  18. MxiA, MxiC and IpaD Regulate Substrate Selection and Secretion Mode in the T3SS of Shigella flexneri.

    PubMed

    Shen, Da-Kang; Blocker, Ariel J

    2016-01-01

    Type III secretion systems (T3SSs) are central virulence devices for many Gram-negative bacterial pathogens of humans, animals & plants. Upon physical contact with eukaryotic host cells, they translocate virulence-mediating proteins, known as effectors, into them during infection. T3SSs are gated from the outside by host-cell contact and from the inside via two cytoplasmic negative regulators, MxiC and IpaD in Shigella flexneri, which together control the effector secretion hierarchy. Their absence leads to premature and increased secretion of effectors. Here, we investigated where and how these regulators act. We demonstrate that the T3SS inner membrane export apparatus protein MxiA plays a role in substrate selection. Indeed, using a genetic screen, we identified two amino acids located on the surface of MxiA's cytoplasmic region (MxiAC) which, when mutated, upregulate late effector expression and, in the case of MxiAI674V, also secretion. The cytoplasmic region of MxiA, but not MxiAN373D and MxiAI674V, interacts directly with the C-terminus of MxiC in a two-hybrid assay. Efficient T3S requires a cytoplasmic ATPase and the proton motive force (PMF), which is composed of the ΔΨ and the ΔpH. MxiA family proteins and their regulators are implicated in utilization of the PMF for protein export. However, our MxiA point mutants show similar PMF utilisation to wild-type, requiring primarily the ΔΨ. On the other hand, lack of MxiC or IpaD, renders the faster T3S seen increasingly dependent on the ΔpH. Therefore, MxiA, MxiC and IpaD act together to regulate substrate selection and secretion mode in the T3SS of Shigella flexneri.

  19. Intradermal delivery of Shigella IpaB and IpaD type III secretion proteins: kinetics of cell recruitment and antigen uptake, mucosal and systemic immunity, and protection across serotypes.

    PubMed

    Heine, Shannon J; Diaz-McNair, Jovita; Andar, Abhay U; Drachenberg, Cinthia B; van de Verg, Lillian; Walker, Richard; Picking, Wendy L; Pasetti, Marcela F

    2014-02-15

    Shigella is one of the leading pathogens contributing to the vast pediatric diarrheal disease burden in low-income countries. No licensed vaccine is available, and the existing candidates are only partially effective and serotype specific. Shigella type III secretion system proteins IpaB and IpaD, which are conserved across Shigella spp., are candidates for a broadly protective, subunit-based vaccine. In this study, we investigated the immunogenicity and protective efficacy of IpaB and IpaD administered intradermally (i.d.) with a double-mutant of the Escherichia coli heat-labile enterotoxin (dmLT) adjuvant using microneedles. Different dosage levels of IpaB and IpaD, with or without dmLT, were tested in mice. Vaccine delivery into the dermis, recruitment of neutrophils, macrophages, dendritic cells, and Langerhans cells, and colocalization of vaccine Ag within skin-activated APC were demonstrated through histology and immunofluorescence microscopy. Ag-loaded neutrophils, macrophages, dendritic cells, and Langerhans cells remained in the tissue at least 1 wk. IpaB, IpaD, and dmLT-specific serum IgG- and IgG-secreting cells were produced following i.d. immunization. The protective efficacy was 70% against Shigella flexneri and 50% against Shigella sonnei. Similar results were obtained when the vaccine was administered intranasally, with the i.d. route requiring 25-40 times lower doses. Distinctively, IgG was detected in mucosal secretions; secretory IgA, as well as mucosal and systemic IgA Ab-secreting cells, were seemingly absent. Vaccine-induced T cells produced IFN-γ, IL-2, TNF-α, IL-17, IL-4, IL-5, and IL-10. These results demonstrate the potential of i.d. vaccination with IpaB and IpaD to prevent Shigella infection and support further studies in humans.

  20. Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells

    PubMed Central

    Kuželová, Kateřina; Grebeňová, Dana; Holoubek, Aleš; Röselová, Pavla; Obr, Adam

    2014-01-01

    P21-activated kinases (PAKs) are involved in the regulation of multiple processes including cell proliferation, adhesion and migration. However, the current knowledge about their function is mainly based on results obtained in adherent cell types. We investigated the effect of group I PAK inhibition using the compound IPA-3 in a variety of human leukemic cell lines (JURL-MK1, MOLM-7, K562, CML-T1, HL-60, Karpas-299, Jurkat, HEL) as well as in primary blood cells. IPA-3 induced cell death with EC50 ranging from 5 to more than 20 μM. Similar range was found for IPA-3-mediated dephosphorylation of a known PAK downstream effector, cofilin. The cell death was associated with caspase-3 activation, PARP cleavage and apoptotic DNA fragmentation. In parallel, 20 μM IPA-3 treatment induced rapid and marked decrease of the cell adhesivity to fibronectin. Per contra, partial reduction of PAK activity using lower dose IPA-3 or siRNA resulted in a slight increase in the cell adhesivity. The changes in the cell adhesivity were also studied using real-time microimpedance measurement and by interference reflection microscopy. Significant differences in the intracellular IPA-3 level among various cell lines were observed indicating that an active mechanism is involved in IPA-3 transport. PMID:24664099

  1. Induction of Necrosis in Human Neutrophils by Shigella flexneri Requires Type III Secretion, IpaB and IpaC Invasins, and Actin Polymerization

    PubMed Central

    François, Mathias; Le Cabec, Véronique; Dupont, Marie-Ange; Sansonetti, Philippe J.; Maridonneau-Parini, Isabelle

    2000-01-01

    Infection by Shigella flexneri is characterized by infiltration of neutrophils in the intestinal mucosa and by a strong inflammatory reaction. Although neutrophils are constitutively programmed to die by apoptosis, we show that isolated human neutrophils undergo necrosis 2 h after infection with virulent S. flexneri strain M90T but not with the virulence plasmid-cured strain BS176. This was demonstrated by the release of azurophil granule proteins concomitant with the release of lactate dehydrogenase (LDH), disruption of the plasma membrane, and absence of DNA fragmentation. Mutants with the mxiD1 gene, coding for an essential component of the secretion type III machinery, or the genes coding for IpaB or IpaC invasins deleted were not cytotoxic. Neutrophil necrosis occurred independently of the bacterial ability to leave phagosomes, and it involved actin polymerization, as the addition of cytochalasin D after phagocytosis of Shigella inhibited the release of LDH. In conclusion, Shigella kills neutrophils by necrosis, a process characterized by the release of tissue-injurious granular proteins. This probably contributes to disruption of the epithelial barrier, leading to the dysentery observed in shigellosis and allowing Shigella to enter its host cells. PMID:10678940

  2. ACT: Acting Out Central Theme.

    ERIC Educational Resources Information Center

    Kise, Joan Duff

    1982-01-01

    The author describes ACT (Acting Out Central Theme), a method for dealing with psychomotor, cognitive, and affective domains in slow readers. The ACT approach involves three sessions which focus on discussion of a theme such as friendship, presentaton of the theme as a skit, and assignment of topics to individual students. (SW)

  3. Dynamics of Composite Haldane Spin Chains in IPA-CuCl3

    SciTech Connect

    Masuda, Takatsugu; Zheludev, Andrey I; Manaka, H.; Regnault, L.-P.; Chung, J.-H.; Qiu, Y.

    2006-01-01

    Magnetic excitations in the quasi-one-dimensional antiferromagnet IPA-CuCl{sub 3} are studied by cold neutron inelastic scattering. Strongly dispersive gap excitations are observed. Contrary to previously proposed models, the system is best described as an asymmetric quantum spin ladder. The observed spectrum is interpreted in terms of composite Haldane spin chains. The key difference from actual S = 1 chains is a sharp cutoff of the single-magnon spectrum at a certain critical wave vector.

  4. Extraction of glucomannan of porang tuber (Amorphophallus onchophillus) by using IPA

    NASA Astrophysics Data System (ADS)

    Wardhani, Dyah Hesti; Nugroho, Fatoni; Muslihuddin, Mohammad

    2015-12-01

    Amorphophallus oncophyllus also known as porang tuber is a local tuber rich of glucomannan. Due to the unique rheological and the gelling properties, glucomannan is widely employed as emulsifier and stabilizer and has been approved as a food additive by the U.S. Food and Drug Administration (FDA). Isolation method of glucomannan from the tuber affects the mannan properties which in turn influence the scope of the applications. Ethanol solution combined with thermal treatment is commonly applied to purify glucomannan. However, the Amorphophallus sp also contains ˜0.2 mg b-carotenes/100 g dry weight, an impurities which difficult to be removed by ethanol-2 propyl alcohol (IPA) is more effective to remove undesirable components of glucomannan including carotenes compared to ethanol. This research objective was to study the effect of extraction time, temperature, IPA concentration, and ratio of solvent and flour on purification of glucomannan of A. onchophillus. Glucomannan content, starch content and viscosity were determined after the extraction. The highest glucomannan concentration was obtained at extraction by using 80% IPA and ratio of solvent/sample 8:1 (ml/g) for 4 h at 75°C. This condition gave 72.8% glucomannan and 2.69% starch with 4,300 cPs viscosity.

  5. Conformational changes in IpaD from Shigella flexneri upon binding bile salts provide insight into the second step of type III secretion.

    PubMed

    Dickenson, Nicholas E; Zhang, Lingling; Epler, Chelsea R; Adam, Philip R; Picking, Wendy L; Picking, William D

    2011-01-18

    Shigella flexneri uses its type III secretion apparatus (TTSA) to inject host-altering proteins into targeted eukaryotic cells. The TTSA is composed of a basal body and an exposed needle with invasion plasmid antigen D (IpaD) forming a tip complex that controls secretion. The bile salt deoxycholate (DOC) stimulates recruitment of the translocator protein IpaB into the maturing TTSA needle tip complex. This process appears to be triggered by a direct interaction between DOC and IpaD. Fluorescence spectroscopy and NMR spectroscopy are used here to confirm the DOC-IpaD interaction and to reveal that IpaD conformational changes upon DOC binding trigger the appearance of IpaB at the needle tip. Förster resonance energy transfer between specific sites on IpaD was used here to identify changes in distances between IpaD domains as a result of DOC binding. To further explore the effects of DOC binding on IpaD structure, NMR chemical shift mapping was employed. The environments of residues within the proposed DOC binding site and additional residues within the "distal" globular domain were perturbed upon DOC binding, further indicating that conformational changes occur within IpaD upon DOC binding. These events are proposed to be responsible for the recruitment of IpaB at the TTSA needle tip. Mutation analyses combined with additional spectroscopic analyses confirm that conformational changes in IpaD induced by DOC binding contribute to the recruitment of IpaB to the S. flexneri TTSA needle tip. These findings lay the foundation for determining how environmental factors promote TTSA needle tip maturation prior to host cell contact.

  6. Liposome-mediated delivery of the p21 activated kinase-1 (PAK-1) inhibitor IPA-3 limits prostate tumor growth in vivo.

    PubMed

    Al-Azayzih, Ahmad; Missaoui, Wided N; Cummings, Brian S; Somanath, Payaningal R

    2016-07-01

    P21 activated kinases-1 (PAK-1) is implicated in various diseases. It is inhibited by the small molecule 'inhibitor targeting PAK1 activation-3' (IPA-3), which is highly specific but metabolically unstable. To address this limitation we encapsulated IPA-3 in sterically stabilized liposomes (SSL). SSL-IPA-3 averaged 139nm in diameter, polydispersity index (PDI) of 0.05, and a zeta potential of -28.1, neither of which changed over 14days; however, the PDI increased to 0.139. Analysis of liposomal IPA-3 levels demonstrated good stability, with 70% of IPA-3 remaining after 7days. SSL-IPA-3 inhibited prostate cancer cell growth in vitro with comparable efficacy to free IPA-3. Excitingly, only a 2day/week dose of SSL-IPA-3 was needed to inhibit the growth of prostate xenografts in vivo, while a similar dose of free IPA-3 was ineffective. These data demonstrate the development and clinical utility of a novel liposomal formulation for the treatment of prostate cancer.

  7. [Regulation of autophagy on dendritic cells during rat liver regeneration by IPA].

    PubMed

    Qiwen, Wang; Wei, Jin; Cuifang, Chang; Cunshuan, Xu

    2015-03-01

    To understand the mechanism underlying autophagy in regulating dendritic cells during rat liver regeneration, we used the method of percoll density gradient centrifugation combined with immunomagnetic bead to isolate dendritic cells, the Rat Genome 230 2.0 Array to determine the expression changes of autophagy-related genes, and Ingenuity Pathway Analysis 9.0 (IPA) to determine the autophagy activities. The results indicated that LC3, BECN1, ATG7 and SQSTM1 genes had significant expression changes during rat liver regeneration. There were 593 genes related to autophagy, among which 210 genes were identified as significant. We also showed that the activity of autophagy was enhanced in the priming phase and teminal phase of liver regeneration, weakened in the proliferative stage by comparative analysis method of IPA. The autophagy-related physiological activities mainly included RNA expression, RNA transcription, cell differentiation and proliferation, involving in PPARα/RXRα activation, acute phase response signaling, TREM1 signaling, IL-6 signaling, IL-8 signaling and IL-1 signaling, whose activities were increased or decreased in liver regeneration. Cluster analysis found that P53 and AMPK signaling participated in the regulation of dendritic cells autophagy, with AMPK signaling in the priming phase of liver regeneration, and both signaling pathways in the terminal phase. We conclude that dendritic cells autophagy played an important role in initiation of the immune response in priming phase and depletion of dendritic cells in late phase during rat liver regeneration.

  8. 28 CFR 100.13 - Directly assignable costs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., COMMUNICATIONS ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.13 Directly assignable costs. (a) A cost is directly assignable to the CALEA compliance effort if it is a plant cost incurred specifically to meet...

  9. Ultrastructural analysis of IpaD at the tip of the nascent MxiH type III secretion apparatus of Shigella flexneri.

    PubMed

    Epler, Chelsea R; Dickenson, Nicholas E; Bullitt, Esther; Picking, Wendy L

    2012-06-29

    Shigella flexneri is a Gram-negative enteric pathogen that is the predominant cause of bacillary dysentery. Shigella uses a type III secretion system to deliver effector proteins that alter normal target cell functions to promote pathogen invasion. The type III secretion apparatus (T3SA) consists of a basal body, an extracellular needle, and a tip complex that is responsible for delivering effectors into the host cell cytoplasm. IpaD [Ipa (invasion plasmid antigen)] is the first protein to localize to the T3SA needle tip, where it prevents premature effector secretion and serves as an environmental sensor for triggering recruitment of the translocator protein IpaB to the needle tip. Thus, IpaD would be expected to form a stable structure whose overall architecture supports its functions. It is not immediately obvious from the published IpaD crystal structure (Protein Data Bank ID 2j0o) how a multimer of IpaD would be incorporated at the tip of the first static T3SA intermediate, nor what its functional role would be in building a mature T3SA. Here, we produce three-dimensional reconstructions from transmission electron microscopy images of IpaD localized at the Shigella T3SA needle tip for comparison to needle tips from a Shigella ipaD-null mutant. The results demonstrate that IpaD resides as a homopentamer at the needle tip of the T3SA. Furthermore, comparison to tips assembled from the distal domain IpaD(Δ192-267) mutation shows that IpaD adopts an elongated conformation that facilitates its ability to control type III secretion and stepwise assembly of the T3SA needle tip complex.

  10. Assignments That Work.

    ERIC Educational Resources Information Center

    Hashimoto, I.

    1986-01-01

    Suggests, on a humorous note, a game-plan for assignment justification and elaboration that utilizes, in a constructive and professional manner, the best of what is known about assignment-making. (EL)

  11. Study of the Gray Scale, Polychromatic, Distortion Invariant Neural Networks Using the Ipa Model.

    NASA Astrophysics Data System (ADS)

    Uang, Chii-Maw

    Research in the optical neural network field is primarily motivated by the fact that humans recognize objects better than the conventional digital computers and the massively parallel inherent nature of optics. This research represents a continuous effort during the past several years in the exploitation of using neurocomputing for pattern recognition. Based on the interpattern association (IPA) model and Hamming net model, many new systems and applications are introduced. A gray level discrete associative memory that is based on object decomposition/composition is proposed for recognizing gray-level patterns. This technique extends the processing ability from the binary mode to gray-level mode, and thus the information capacity is increased. Two polychromatic optical neural networks using color liquid crystal television (LCTV) panels for color pattern recognition are introduced. By introducing a color encoding technique in conjunction with the interpattern associative algorithm, a color associative memory was realized. Based on the color decomposition and composition technique, a color exemplar-based Hamming net was built for color image classification. A shift-invariant neural network is presented through use of the translation invariant property of the modulus of the Fourier transformation and the hetero-associative interpattern association (IPA) memory. To extract the main features, a quadrantal sampling method is used to sampled data and then replace the training patterns. Using the concept of hetero-associative memory to recall the distorted object. A shift and rotation invariant neural network using an interpattern hetero-association (IHA) model is presented. To preserve the shift and rotation invariant properties, a set of binarized-encoded circular harmonic expansion (CHE) functions at the Fourier domain is used as the training set. We use the shift and symmetric properties of the modulus of the Fourier spectrum to avoid the problem of centering the CHE

  12. 75 FR 7266 - Roaring Fork Valley Physicians I.P.A.; Analysis of the Agreement Containing Consent Order to Aid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... Roaring Fork Valley Physicians I.P.A.; Analysis of the Agreement Containing Consent Order to Aid Public.... Comments should refer to ``Roaring Fork Valley, File No. 061 0172'' to facilitate the organization of... release describing it. A comment filed in paper form should include the ``Roaring Fork Valley, File...

  13. Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

    PubMed Central

    Suzuki, Shiho; Mimuro, Hitomi; Kim, Minsoo; Ogawa, Michinaga; Ashida, Hiroshi; Toyotome, Takahito; Franchi, Luigi; Suzuki, Masato; Sanada, Takahito; Suzuki, Toshihiko; Tsutsui, Hiroko; Núñez, Gabriel; Sasakawa, Chihiro

    2014-01-01

    When nucleotide-binding oligomerization domain–like receptors (NLRs) sense cytosolic-invading bacteria, they induce the formation of inflammasomes and initiate an innate immune response. In quiescent cells, inflammasome activity is tightly regulated to prevent excess inflammation and cell death. Many bacterial pathogens provoke inflammasome activity and induce inflammatory responses, including cell death, by delivering type III secreted effectors, the rod component flagellin, and toxins. Recent studies indicated that Shigella deploy multiple mechanisms to stimulate NLR inflammasomes through type III secretion during infection. Here, we show that Shigella induces rapid macrophage cell death by delivering the invasion plasmid antigen H7.8 (IpaH7.8) enzyme 3 (E3) ubiquitin ligase effector via the type III secretion system, thereby activating the NLR family pyrin domain-containing 3 (NLRP3) and NLR family CARD domain-containing 4 (NLRC4) inflammasomes and caspase-1 and leading to macrophage cell death in an IpaH7.8 E3 ligase-dependent manner. Mice infected with Shigella possessing IpaH7.8, but not with Shigella possessing an IpaH7.8 E3 ligase-null mutant, exhibited enhanced bacterial multiplication. We defined glomulin/flagellar-associated protein 68 (GLMN) as an IpaH7.8 target involved in IpaH7.8 E3 ligase-dependent inflammasome activation. This protein originally was identified through its association with glomuvenous malformations and more recently was described as a member of a Cullin ring ligase inhibitor. Modifying GLMN levels through overexpression or knockdown led to reduced or augmented inflammasome activation, respectively. Macrophages stimulated with lipopolysaccharide/ATP induced GLMN puncta that localized with the active form of caspase-1. Macrophages from GLMN+/− mice were more responsive to inflammasome activation than those from GLMN+/+ mice. Together, these results highlight a unique bacterial adaptation that hijacks inflammasome activation via

  14. Identification of the bile salt binding site on ipad from Shigella flexneri and the influence of ligand binding on IpaD structure

    SciTech Connect

    Barta, Michael L.; Guragain, Manita; Adam, Philip; Dickenson, Nicholas E.; Patil, Mrinalini; Geisbrecht, Brian V.; Picking, Wendy L.; Picking, William D.

    2012-10-25

    Type III secretion (TTS) is an essential virulence factor for Shigella flexneri, the causative agent of shigellosis. The Shigella TTS apparatus (TTSA) is an elegant nano-machine that is composed of a basal body, an external needle to deliver effectors into human cells, and a needle tip complex that controls secretion activation. IpaD is at the tip of the nascent TTSA needle where it controls the first step of TTS activation. The bile salt deoxycholate (DOC) binds to IpaD to induce recruitment of the translocator protein IpaB into the maturing tip complex. We recently used spectroscopic analyses to show that IpaD undergoes a structural rearrangement that accompanies binding to DOC. Here, we report a crystal structure of IpaD with DOC bound and test the importance of the residues that make up the DOC binding pocket on IpaD function. IpaD binds DOC at the interface between helices {alpha}3 and {alpha}7, with concomitant movement in the orientation of helix {alpha}7 relative to its position in unbound IpaD. When the IpaD residues involved in DOC binding are mutated, some are found to lead to altered invasion and secretion phenotypes. These findings suggest that adoption of a DOC-bound structural state for IpaD primes the Shigella TTSA for contact with host cells. The data presented here and in the studies leading up to this work provide the foundation for developing a model of the first step in Shigella TTS activation.

  15. The Failed Writing Assignment.

    ERIC Educational Resources Information Center

    Swyt, Wendy

    1995-01-01

    Discusses an unsuccessful English 101 writing assignment in which students were asked to analyze a Gary Larson cartoon. Examines critically the type of assignment that seeks to address and incorporate the student writer's "local knowledge" of cultural texts, while at the same time containing what counts as knowledge within limited parameters of…

  16. Use of IPA to demonstrate loss of forest interior birds from isolated woodlots

    USGS Publications Warehouse

    Robbins, C.S.; Boone, D.D.; Purroy, F.J.

    1983-01-01

    'Empleo de indices puntuales de abundancia (IPA) para demostrar la perdida de aves forestales en bosques aislados'. En Maryland, E.U., se seleccionaron bloques boscosos de diferente superficie, divididos en seis clase de tamano (2,8-6 ha, 7-14, 20-30, 34-80, 105-1300, mayores de 4000 ha). En estas ?islas' forestales fue programado un conjunto de muestreos puntuales con estas caracteristicas: 1) Cada punto se visito tres veces. 2) En cada visita se hicieron cuatro censos consecutivos de 5 minutos de duracion, empleando diferentes simbolos para machos cantores, adultos no cantores, aves en vuelo y aves inmaduras. 3) Los conteos se hicieron en tres epocas: final de Mayo, mitad de Junio y final de Junio. 4) Se dividio el tiempo de censo en tres priodos horarios: 5,15-6,30 ; 6,30-8; 8-9,30 hrs. 5) Los puntos se agruparon en co juntos de 4 a 9, considerando que un conjunto es el nlimero que un observador puede cubrir por manana. 6) La vegetacion fue descrita exhaustivamente en cuanto composicion y fisionomla. El principal objetivo que se busca consiste en conocer los requisitos areales de ciertas especies de bosque muy sensibles a la fragmentacion del habitat. Puede observarse (Figura 1) que una serie de migrantes de largo alcance se asientan en relacion con el aumento de la superficie del rodal arbo1ado, sabre todo en macizos de 4.000 o mas hectareas. Sin embargo, las especies sedentarias (Fig. 2) tienen pauta de presencia irregular en funcion del area, forestal, con tendencia a presentarse menos en los bosques mas extensos, Dryocopus pileatus, por excepcion, reacciona negativamente al pequeno tamano de la parcela arbolado, prefiriendo bosques grandes. Parecida respuesta da tambien Sitta carolinensis. Aunque se sabe poco de las exigencias areales de las aves forestales americanas, el metodo de los IPA resulta muy adecuado para esta clase de investigacion de tanto interes en gestion ambiental, posibilitando colectar gran cantidad de datos comparables en un periodo de

  17. Between chaos and petrification: a summary of the Fifth IPA Conference of Training Analysts.

    PubMed

    Wallerstein, R S

    1993-02-01

    The Fifth IPA Conference of Training Analysts was devoted to the problems in the integration of different theoretical and clinical perspectives in the formation of psychoanalysts, the dialectical tensions between rigidity and stultification on the one hand, and a chaotic 'anything goes' on the other. Seven presentations, from the three major geographical regions and representing a range of theoretical perspectives, though drawing upon common and shared clinical and training experiences, were widely divergent in both their descriptions and their prescriptions. The presentations by Janice de Saussure of Geneva, by Charles Kligerman of Chicago, by Marcio de Freitas Giovanetti of São Paulo, Raquel Zak de Goldstein of Buenos Aires, André Green of Paris, José Infante of Chile and André Lussier of Montreal, are arrayed along a spectrum from the most conservative to the most sweepingly radical critique of our organisations and our practices; what is shared by these seven quite disparate presentations from so many ideologically and geographically diverse quarters is a widespread dissatisfaction with so many aspects of, and so many consequences of, the operation or our extant tripartite training structure bequeathed to us by Eitingon and his colleagues almost 75 years ago and hardly changed at all ever since. PMID:8454399

  18. Between chaos and petrification: a summary of the Fifth IPA Conference of Training Analysts.

    PubMed

    Wallerstein, R S

    1993-02-01

    The Fifth IPA Conference of Training Analysts was devoted to the problems in the integration of different theoretical and clinical perspectives in the formation of psychoanalysts, the dialectical tensions between rigidity and stultification on the one hand, and a chaotic 'anything goes' on the other. Seven presentations, from the three major geographical regions and representing a range of theoretical perspectives, though drawing upon common and shared clinical and training experiences, were widely divergent in both their descriptions and their prescriptions. The presentations by Janice de Saussure of Geneva, by Charles Kligerman of Chicago, by Marcio de Freitas Giovanetti of São Paulo, Raquel Zak de Goldstein of Buenos Aires, André Green of Paris, José Infante of Chile and André Lussier of Montreal, are arrayed along a spectrum from the most conservative to the most sweepingly radical critique of our organisations and our practices; what is shared by these seven quite disparate presentations from so many ideologically and geographically diverse quarters is a widespread dissatisfaction with so many aspects of, and so many consequences of, the operation or our extant tripartite training structure bequeathed to us by Eitingon and his colleagues almost 75 years ago and hardly changed at all ever since.

  19. iPAS: AES Flight System Technology Maturation for Human Spaceflight

    NASA Technical Reports Server (NTRS)

    Othon, William L.

    2014-01-01

    In order to realize the vision of expanding human presence in space, NASA will develop new technologies that can enable future crewed spacecraft to go far beyond Earth orbit. These technologies must be matured to the point that future project managers can accept the risk of incorporating them safely and effectively within integrated spacecraft systems, to satisfy very challenging mission requirements. The technologies must also be applied and managed within an operational context that includes both on-board crew and mission support on Earth. The Advanced Exploration Systems (AES) Program is one part of the NASA strategy to identify and develop key capabilities for human spaceflight, and mature them for future use. To support this initiative, the Integrated Power Avionics and Software (iPAS) environment has been developed that allows engineers, crew, and flight operators to mature promising technologies into applicable capabilities, and to assess the value of these capabilities within a space mission context. This paper describes the development of the integration environment to support technology maturation and risk reduction, and offers examples of technology and mission demonstrations executed to date.

  20. The International University Courses on Permafrost (IUCP): an IPY Education Initiative From the International Permafrost Association (IPA)

    NASA Astrophysics Data System (ADS)

    Prick, A.; Christiansen, H. H.

    2006-12-01

    Worldwide, only very few dedicated permafrost courses exist at university level today. This significantly limits the development of new permafrost researchers. Therefore, the International Permafrost Association (IPA) has developed an overview of International University Courses on Permafrost (IUCP), as part of its participation in the IPY. This polar-related educational program covers cross-cutting activities of the four core IPY-IPA endorsed cluster projects that constitute the IPY Permafrost Programme: Permafrost Observatory Project: A Contribution to the Thermal State of Permafrost (TSP; Project 50); Antarctic and sub-Antarctic Permafrost, Periglacial and Soil Environments (ANTPAS; Project 33); Arctic Circumpolar Coastal Observatory Network (ACCO-Net; Project 90); Carbon Pools in Permafrost Regions (CAPP; Project 373). The IUCP collects information about existing and new IPY permafrost courses worldwide, to encourage a broad international student participation in the existing courses. All courses dealing with permafrost and periglacial geomorphology within the science and engineering disciplines and organized in 2007 to 2009 in both hemispheres qualify for IUCP. Some courses are exclusively field-based and take place in various polar regions, offering students a unique opportunity to gather field experience. Other courses are theoretical and classroom-based or include only limited time in the field. All course levels are taken into account, from undergraduate to doctorate level; the IPA also encourages young professional participation in the IUCP. IPA- IPY education coordinators in each country are providing relevant information. IUCP course information is presented on the IPA webpage. The use of web resource and search tools allow easy access to course contents. The IUCP course numbers by countries as by August 2006 is: Argentina (1), Belgium (1), Canada (29), China (11), Denmark (1), France (2), Japan (7), Mongolia (1), Netherlands (4), New Zealand (1

  1. Designing Cyber-Assignments.

    ERIC Educational Resources Information Center

    Drogemuller, Richard

    1997-01-01

    Recommends that teachers prevent plagiarism by structuring research assignments so that copying material from references is very difficult. Suggests that teachers be specific, select relevant topics, and insist on full referencing. (DDR)

  2. My Favorite Assignment.

    ERIC Educational Resources Information Center

    Post, Robert E.; Johnson, Jack E.

    1982-01-01

    Presents two assignments that show (1) how George Orwell's "Politics and the English Language" can be applied to business writing and (2) how structured student-teacher conferences can generate enthusiasm for oral expression in a business communication course. (AEA)

  3. Personal Writing Assignments.

    ERIC Educational Resources Information Center

    Connors, Robert J.

    1987-01-01

    Examines one element of rhetorical history--the sorts of subjects teachers have assigned students and their change from objective, centripetal writing tasks to subjective, centrifugal tasks. Documents the historical evolution of rhetorical tradition. (AEW)

  4. Functional insights into the Shigella type III needle tip IpaD in secretion control and cell contact.

    PubMed

    Schiavolin, Lionel; Meghraoui, Alaeddine; Cherradi, Youness; Biskri, Latéfa; Botteaux, Anne; Allaoui, Abdelmounaaïm

    2013-04-01

    Type III secretion apparatus (T3SA) are complex nanomachines that insert a translocation pore into the host cell membrane through which effector proteins are injected into the cytosol. In Shigella, the pore is inserted by a needle tip complex that also controls secretion. IpaD is the key protein that rules the composition of the tip complex before and upon cell contact or Congo red (CR) induction. However, how IpaD is involved in secretion control and translocon insertion remains not fully understood. Here, we report the phenotypic analysis of 20 10-amino acids deletion variants all along the coiled-coil and the central domains of IpaD (residues 131-332). Our results highlight three classes of T3S phenotype; (i) wild-type secretion, (ii) constitutive secretion of all classes of effectors, and (iii) constitutive secretion of translocators and early effectors, but not of late effectors. Our data also suggest that the composition of the tip complex defines both the T3SA inducibility state and late effectors secretion. Finally, we shed light on a new aspect regarding the contact of the needle tip with cell membrane by uncoupling the Shigella abilities to escape macrophage vacuole, and to insert the translocation pore or to invade non-phagocytic cells.

  5. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Assignment of Rights to Benefits § 433.146 Rights assigned; assignment method. (a) Except as specified...

  6. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Assignment of Rights to Benefits § 433.146 Rights assigned; assignment method. (a) Except as specified...

  7. Modelling Focused Learning in Role Assignment.

    ERIC Educational Resources Information Center

    Matessa, Michael; Anderson, John R.

    2000-01-01

    ACT-R is a theory of cognition that is capable of learning the relative usefulness of alternative rules. A model using this implicit procedural learning mechanism is described that explains results from a concept formation task created by McDonald and MacWhinney (1991), a role assignment created by Blackwell (1995), and a new role assignment…

  8. 24 CFR 221.770 - Assignment option.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES LOW COST AND... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Assignment option. 221.770 Section 221.770 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  9. 24 CFR 221.255 - Assignment option.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES LOW COST AND MODERATE INCOME MORTGAGE INSURANCE-SAVINGS CLAUSE Contract Rights and Obligations-Low Cost Homes § 221.255... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Assignment option. 221.255...

  10. 24 CFR 221.770 - Assignment option.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES LOW COST AND... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.770 Section 221.770 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  11. 24 CFR 221.255 - Assignment option.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES LOW COST AND MODERATE INCOME MORTGAGE INSURANCE-SAVINGS CLAUSE Contract Rights and Obligations-Low Cost Homes § 221.255... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.255...

  12. 5 CFR 334.106 - Requirement for written agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TEMPORARY ASSIGNMENTS UNDER THE INTERGOVERNMENTAL PERSONNEL ACT (IPA) § 334.106 Requirement for written..., Indian tribal government, institution of higher education, or other eligible organization must enter...

  13. Principals Make Assignments Matter

    ERIC Educational Resources Information Center

    Dougherty, Eleanor

    2013-01-01

    The inner-city high school in Washington, DC, that Guillaume Gendre joined as an assistant principal had a modest reputation for achievement but was nevertheless challenged to raise expectations for student work. In other schools, Gendre had used assignments--a specific kind of instructional task in which students are charged to think about an…

  14. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... services under 34 CFR 361.42, the EN or State VR agency acting as an EN may ask the PM to take your ticket... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting...

  15. Gain weighted eigenspace assignment

    NASA Technical Reports Server (NTRS)

    Davidson, John B.; Andrisani, Dominick, II

    1994-01-01

    This report presents the development of the gain weighted eigenspace assignment methodology. This provides a designer with a systematic methodology for trading off eigenvector placement versus gain magnitudes, while still maintaining desired closed-loop eigenvalue locations. This is accomplished by forming a cost function composed of a scalar measure of error between desired and achievable eigenvectors and a scalar measure of gain magnitude, determining analytical expressions for the gradients, and solving for the optimal solution by numerical iteration. For this development the scalar measure of gain magnitude is chosen to be a weighted sum of the squares of all the individual elements of the feedback gain matrix. An example is presented to demonstrate the method. In this example, solutions yielding achievable eigenvectors close to the desired eigenvectors are obtained with significant reductions in gain magnitude compared to a solution obtained using a previously developed eigenspace (eigenstructure) assignment method.

  16. 28 CFR 100.13 - Directly assignable costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., COMMUNICATIONS ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.13 Directly assignable costs. (a) A cost is... projects, business units, or cost objectives of the carrier shall not be charged to the CALEA...

  17. Pathways to assignment of payees.

    PubMed

    Rosen, Marc I; Ablondi, Karen; Black, Anne C; Serowik, Kristin L; Rowe, Michael

    2014-04-01

    How clients come to be assigned representative payees and/or conservators to manage their funds is not well understood. We compared clients assigned a payee during a clinical trial of a money management-based intervention to those not assigned payees and examined antecedents to payee assignment. One year after randomization, significantly more clients assigned to the advisor teller money manager (ATM) money management intervention were assigned payees than participants in the control condition (10 of 47 vs. 2 of 43; p = .02); those assigned payees had lower baseline GAF scores and participated more in study therapies. Several ATM clients were assigned payees after third parties paid more attention to clients' finances, and others after having negotiated storage of their funds with the ATM money manager during the study. Assignment of payees appears to be influenced by whether third parties critically attend to how clients' manage funds and by clients' receptiveness to having a payee.

  18. Antidepressant-like and anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa).

    PubMed

    Zhang, Li-Ming; Zhao, Nan; Guo, Wen-Zhi; Jin, Zeng-Liang; Qiu, Zhi-Kun; Chen, Hong-Xia; Xue, Rui; Zhang, You-Zhi; Yang, Ri-Fang; Li, Yun-Feng

    2014-06-01

    It has been demonstrated that the translocator protein (18 kDa) (TSPO) plays an important role in stress-response and stress-related disorders, such as anxiety and depression, by affecting the production of neurosteroids, supporting the potential use of selective TSPO ligands as antidepressant or anxiolytic drugs. N-ethyl-N-(2-pyridinylmethyl)- 2-(3,4-ichlorophenyl)- 7-methylimidazo [1,2-a] pyridine-3-acetamide hydrochloride (YL-IPA08), a novel TSPO ligand that has been synthesized at our institute, exerted a high affinity for TSPO in a crude mitochondrial fraction prepared from rat cerebellum but exhibited only a negligible affinity for the central benzodiazepine receptor. As expected, YL-IPA08 incubation with the cultured rat astrocyte cells increased the pregnenolone and progesterone concentration from the cultured medium. Moreover, YL-IPA08 produced significant antidepressant-like and anxiolytic-like effects in a series of mouse and rat behavior models. In addition, the antidepressant-like behavior of YL-IPA08 was totally blocked by the TSPO antagonist PK11195 in a tail suspension test, and the anxiolytic effect was blocked by PK11195 but not by a CBR antagonist in the elevated plus-maze test. Furthermore, compared with the CBR agonist diazepam, YL-IPA08 had no myorelaxant effects and did not affect the motor coordination, memory or hexobarbitone-induced sleep in mice. Overall, these results indicate that YL-IPA08 is a more potent and selective TSPO ligand, which exerts antidepressant-like and anxiolytic-like effects on behaviors that are mediated by TSPO but does not cause the side effects that are typically associated with conventional benzodiazepines.

  19. Involving Students in Assignment Evaluation.

    ERIC Educational Resources Information Center

    Rademacher, Joyce A.

    2000-01-01

    The first part of this article explains the connection between planning, presenting, and evaluating assignments for students who demonstrate ineffective assignment completion strategies. The second part offers specific guidelines for teaching students to check their own finished assignments according to a set of quality work criteria. (Contains…

  20. Structural Case Assignment in Korean

    ERIC Educational Resources Information Center

    Koak, Heeshin

    2012-01-01

    In this dissertation, I aim to provide a theory on the distribution of structural Case in Korean. I propose the following Structural Case Assignment Hypothesis (SCAH) regarding the assignment of structural Case: "Structural Case is assigned by phase heads (C: nominative; v: accusative) to every argument in the c-command domain of the phase…

  1. Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion.

    PubMed

    Mounier, Joëlle; Boncompain, Gaëlle; Senerovic, Lidija; Lagache, Thibault; Chrétien, Fabrice; Perez, Franck; Kolbe, Michael; Olivo-Marin, Jean-Christophe; Sansonetti, Philippe J; Sauvonnet, Nathalie

    2012-09-13

    Shigella infection causes destruction of the human colonic epithelial barrier. The Golgi network and recycling endosomes are essential for maintaining epithelial barrier function. Here we show that Shigella epithelial invasion induces fragmentation of the Golgi complex with consequent inhibition of both secretion and retrograde transport in the infected host cell. Shigella induces tubulation of the Rab11-positive compartment, thereby affecting cell surface receptor recycling. The molecular process underlying the observed damage to the Golgi complex and receptor recycling is a massive redistribution of plasma membrane cholesterol to the sites of Shigella entry. IpaB, a virulence factor of Shigella that is known to bind cholesterol, is necessary and sufficient to induce Golgi fragmentation and reorganization of the recycling compartment. Shigella infection-induced Golgi disorganization was also observed in vivo, suggesting that this mechanism affecting the sorting of cell surface molecules likely contributes to host epithelial barrier disruption associated with Shigella pathogenesis.

  2. 32 CFR Appendix C to Part 37 - What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs? C Appendix C to Part 37 National Defense Department... INVESTMENT AGREEMENTS Pt. 37, App. C Appendix C to Part 37—What Is the Desired Coverage for Periodic...

  3. 32 CFR Appendix C to Part 37 - What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs? C Appendix C to Part 37 National Defense Department... INVESTMENT AGREEMENTS Pt. 37, App. C Appendix C to Part 37—What Is the Desired Coverage for Periodic...

  4. 32 CFR Appendix C to Part 37 - What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs? C Appendix C to Part 37 National Defense Department... INVESTMENT AGREEMENTS Pt. 37, App. C Appendix C to Part 37—What Is the Desired Coverage for Periodic...

  5. 32 CFR 37.675 - Must I report when I enter into a TIA allowing a for-profit firm to use an IPA?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Must I report when I enter into a TIA allowing a for-profit firm to use an IPA? 37.675 Section 37.675 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Affecting Participants'...

  6. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

    PubMed Central

    Wang, Yiming; Gratzke, Christian; Tamalunas, Alexander; Wiemer, Nicolas; Ciotkowska, Anna; Rutz, Beata; Waidelich, Raphaela; Strittmatter, Frank; Liu, Chunxiao; Stief, Christian G.; Hennenberg, Martin

    2016-01-01

    Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients’ adherence is particularly low to combination therapies of 5α-reductase inhibitors and α1-adrenoceptor antagonists, which are supposed to target contraction and growth simultaneously. Consequently, molecular etiology of benign prostatic hyperplasia (BPH) and new compounds interfering with smooth muscle contraction or growth in the prostate are of high interest. Here, we studied effects of p21-activated kinase (PAK) inhibitors (FRAX486, IPA3) in hyperplastic human prostate tissues, and in stromal cells (WPMY-1). In hyperplastic prostate tissues, PAK1, -2, -4, and -6 may be constitutively expressed in catecholaminergic neurons, while PAK1 was detected in smooth muscle and WPMY-1 cells. Neurogenic contractions of prostate strips by electric field stimulation were significantly inhibited by high concentrations of FRAX486 (30 μM) or IPA3 (300 μM), while noradrenaline- and phenylephrine-induced contractions were not affected. FRAX486 (30 μM) inhibited endothelin-1- and -2-induced contractions. In WPMY-1 cells, FRAX486 or IPA3 (24 h) induced concentration-dependent (1–10 μM) degeneration of actin filaments. This was paralleled by attenuation of proliferation rate, being observed from 1 to 10 μM FRAX486 or IPA3. Cytotoxicity of FRAX486 and IPA3 in WPMY-1 cells was time- and concentration-dependent. Stimulation of WPMY-1 cells with endothelin-1 or dihydrotestosterone, but not noradrenaline induced PAK phosphorylation, indicating PAK activation by endothelin-1. Thus, PAK inhibitors may inhibit neurogenic and endothelin-induced smooth muscle contractions in the hyperplastic human prostate, and growth of stromal cells. Targeting prostate smooth muscle contraction and stromal growth at once by a single compound is principally possible, at least under

  7. Balanced input-output assignment

    NASA Technical Reports Server (NTRS)

    Gawronski, W.; Hadaegh, F. Y.

    1989-01-01

    Actuator/sensor locations and balanced representations of linear systems are considered for a given set of controllability and observability grammians. The case of equally controlled and observed states is given special attention. The assignability of grammians is examined, and the conditions for their existence are presented, along with several algorithms for their determination. Although an arbitrary positive semidefinite matrix is not always assignable, the identity grammian is shown to be always assignable. The results are extended to the case of flexible structures.

  8. Automated protein NMR resonance assignments.

    PubMed

    Wan, Xiang; Xu, Dong; Slupsky, Carolyn M; Lin, Guohui

    2003-01-01

    NMR resonance peak assignment is one of the key steps in solving an NMR protein structure. The assignment process links resonance peaks to individual residues of the target protein sequence, providing the prerequisite for establishing intra- and inter-residue spatial relationships between atoms. The assignment process is tedious and time-consuming, which could take many weeks. Though there exist a number of computer programs to assist the assignment process, many NMR labs are still doing the assignments manually to ensure quality. This paper presents (1) a new scoring system for mapping spin systems to residues, (2) an automated adjacency information extraction procedure from NMR spectra, and (3) a very fast assignment algorithm based on our previous proposed greedy filtering method and a maximum matching algorithm to automate the assignment process. The computational tests on 70 instances of (pseudo) experimental NMR data of 14 proteins demonstrate that the new score scheme has much better discerning power with the aid of adjacency information between spin systems simulated across various NMR spectra. Typically, with automated extraction of adjacency information, our method achieves nearly complete assignments for most of the proteins. The experiment shows very promising perspective that the fast automated assignment algorithm together with the new score scheme and automated adjacency extraction may be ready for practical use. PMID:16452794

  9. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE FISCAL ADMINISTRATION Third Party...

  10. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE FISCAL ADMINISTRATION Third Party...

  11. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE FISCAL ADMINISTRATION Third Party...

  12. Key Words in Instruction Assignment.

    ERIC Educational Resources Information Center

    Callison, Daniel

    2000-01-01

    Discusses library-based assignments for information literacy and suggests the focus needs to change from information location to information use. Topics include online searching; reporting facts; more thoughtful research projects to develop skills; pitfalls of library assignments; and how to make information sources play a secondary role. (LRW)

  13. 7 CFR 1230.91 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... recordkeeping requirements contained in this subpart have been approved by the Office of Management and...

  14. 7 CFR 1260.316 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have...

  15. 7 CFR 1260.316 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have...

  16. 7 CFR 1260.316 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have...

  17. 7 CFR 1260.316 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have...

  18. 7 CFR 1260.316 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE... the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have...

  19. An Assignment Sequence for Underprepared Writers.

    ERIC Educational Resources Information Center

    Nimmo, Kristi

    2000-01-01

    Presents a sequenced writing assignment on shopping to aid basic writers. Describes a writing assignment focused around online and mail-order shopping. Notes steps in preparing for the assignment, the sequence, and discusses responses to the assignments. (SC)

  20. Node assignment in heterogeneous computing

    NASA Technical Reports Server (NTRS)

    Som, Sukhamoy

    1993-01-01

    A number of node assignment schemes, both static and dynamic, are explored for the Algorithm to Architecture Mapping Model (ATAMM). The architecture under consideration consists of heterogeneous processors and implements dataflow models of real-time applications. Terminology is developed for heterogeneous computing. New definitions are added to the ATAMM for token and assignment classifications. It is proved that a periodic execution is possible for dataflow graphs. Assignment algorithms are developed and proved. A design procedure is described for satisfying an objective function in an heterogeneous architecture. Several examples are provided for illustration.

  1. Patients’ Experience of therapeutic footwear whilst living at risk of neuropathic diabetic foot ulceration: an interpretative phenomenological analysis (IPA)

    PubMed Central

    2014-01-01

    Background Previous work has found that people with diabetes do not wear their therapeutic footwear as directed, but the thinking behind this behaviour is unclear. Adherence to therapeutic footwear advice must improve in order to reduce foot ulceration and amputation risk in people with diabetes and neuropathy. Therefore this study aimed to explore the psychological influences and personal experiences behind the daily footwear selection of individuals with diabetes and neuropathy. Methods An interpretative phenomenological analysis (IPA) approach was used to explore the understanding and experience of therapeutic footwear use in people living at risk of diabetic neuropathic foot ulceration. This study benefited from the purposive selection of a small sample of four people and used in-depth semi structured interviews because it facilitated the deep and detailed examination of personal thoughts and feelings behind footwear selection. Findings Four overlapping themes that interact to regulate footwear choice emerged from the analyses: a) Self-perception dilemma; resolving the balance of risk experienced by people with diabetes and neuropathy day to day, between choosing to wear footwear to look and feel normal and choosing footwear to protect their feet from foot ulceration; b) Reflective adaption; The modification and individualisation of a set of values about footwear usage created in the minds of people with diabetes and neuropathy; c) Adherence response; The realignment of footwear choice with personal values, to reinforce the decision not to change behaviour or bring about increased footwear adherence, with or without appearance management; d) Reality appraisal; A here and now appraisal of the personal benefit of footwear choice on emotional and physical wellbeing, with additional consideration to the preservation of therapeutic footwear. Conclusion For some people living at risk of diabetic neuropathic foot ulceration, the decision whether or not to wear

  2. Expert systems for personnel assignment

    SciTech Connect

    Hardee, J.L.; Liepins, G.

    1986-01-01

    In order to reduce stress on assignment personnel (detailers) and ensure maximum fairness and consistency in the Navy's personnel assignment process, The Navy Military Personnel Command (NMPC) has begun to explore the potential use of expert systems to supplement current manual and computerized distribution methods. The Detailer's Assistant expert system is being developed to improve the detailers' ability to satisfy the needs of their constituents and Navy management. An initial prototype of the Detailer's Assistant is now being evaluated. Numerous upgrades and extensions should lead to an operational system in the near future. Further development to a production system will involve additional research in machine learning, intelligent database methods, and cooperating expert systems.

  3. 22 CFR Exhibit B to Part 204 - Assignment

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of ___, ___ the “Guaranty”), between the Lender and the United States of America, acting through the... payment to the undersigned as of the date hereof. By Name Title Dated Accepted: UNITED STATES OF AMERICA.... B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in...

  4. 22 CFR Exhibit B to Part 204 - Assignment

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of ___, ___ the “Guaranty”), between the Lender and the United States of America, acting through the... payment to the undersigned as of the date hereof. By Name Title Dated Accepted: UNITED STATES OF AMERICA.... B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in...

  5. 22 CFR Exhibit B to Part 204 - Assignment

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of ___, ___ the “Guaranty”), between the Lender and the United States of America, acting through the... payment to the undersigned as of the date hereof. By Name Title Dated Accepted: UNITED STATES OF AMERICA.... B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in...

  6. 22 CFR Exhibit B to Part 204 - Assignment

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of ___, ___ the “Guaranty”), between the Lender and the United States of America, acting through the... payment to the undersigned as of the date hereof. By Name Title Dated Accepted: UNITED STATES OF AMERICA.... B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in...

  7. 22 CFR Exhibit B to Part 204 - Assignment

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of ___, ___ the “Guaranty”), between the Lender and the United States of America, acting through the... payment to the undersigned as of the date hereof. By Name Title Dated Accepted: UNITED STATES OF AMERICA.... B Exhibit B to Part 204—Assignment The undersigned, being the registered owner of a Note in...

  8. 48 CFR 552.232-23 - Assignment of Claims.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... following is substituted therefor: In order to prevent confusion and delay in making payment, the Contractor..., including any Federal lending agency, under the provisions of the Assignment of Claims Act, as amended, 31 U.S.C. 3727, 41 U.S.C. 15 (hereinafter referred to as “the Act”), all amounts due or to become...

  9. 48 CFR 52.232-23 - Assignment of Claims.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... described in the preceding sentence. (b) Any assignment or reassignment authorized under the Act and this... writing. (End of clause) Alternate I (APR 1984). If a no-setoff commitment is to be included in the contract (see 32.801 and 32.803(d)), add the following sentence at the end of paragraph (a) of the...

  10. Co-administration of rIpaB domain of Shigella with rGroEL of S. Typhi enhances the immune responses and protective efficacy against Shigella infection

    PubMed Central

    Chitradevi, Sekar Tamil Selvi; Kaur, Gurpreet; Uppalapati, Sivaramakrishna; Yadav, Anandprakash; Singh, Dependrapratap; Bansal, Anju

    2015-01-01

    Shigella species cause severe bacillary dysentery in humans and are associated with high morbidity and mortality. The Invasion plasmid antigen (IpaB) protein, which is conserved across all Shigella spp., induces macrophage cell death and is required to invade host cells. The present study evaluates the immunogenicity and protective efficacy of the recombinant (r) domain region of IpaB (rIpaB) of S. flexneri. rIpaB was administered either alone or was co-administered with the rGroEL (heat shock protein 60) protein from S. Typhi as an adjuvant in a mouse model of intranasal immunization. The IpaB domain region (37 kDa) of S. flexneri was amplified from an invasion plasmid, cloned, expressed in BL21 Escherichia coli cells and purified. Immunization with the rIpaB domain alone stimulated both humoral and cell-mediated immune responses. Furthermore, robust antibody (IgG, IgA) and T-cell responses were induced when the rIpaB domain was co-administered with rGroEL. Antibody isotyping revealed higher IgG1 and IgG2a antibody titers and increased interferon-gamma (IFN-γ) secretion in the co-administered group. Immunization of mice with the rIpaB domain alone protected 60%–70% of the mice from lethal infection by S. flexneri, S. boydii and S. sonnei, whereas co-administration with rGroEL increased the protective efficacy to 80%–85%. Organ burden and histopathological studies also revealed a significant reduction in lung infection in the co-immunized mice compared with mice immunized with the rIpaB domain alone. This study emphasizes that the co-administration of the rIpaB domain and rGroEL protein improves immune responses in mice and increases protective efficacy against Shigella infection. This is also the first report to evaluate the potential of the GroEL (Hsp 60) protein of S. Typhi as an adjuvant molecule, thereby overcoming the need for commercial adjuvants. PMID:25640657

  11. Some remarks on assignment maps

    NASA Astrophysics Data System (ADS)

    Masillo, F.; Scolarici, G.; Solombrino, L.

    2011-01-01

    We study the properties of general linear assignment maps, showing that positivity axiom can be suitably relaxed, and propose a new class of dynamical maps (generalized dynamics). A puzzling result, arising in such a context in quantum information theory, is also discussed.

  12. Who Benefits from Homework Assignments?

    ERIC Educational Resources Information Center

    Ronning, Marte

    2011-01-01

    Using Dutch data on pupils in elementary school this paper is the first empirical study to analyze whether assigning homework has a heterogeneous impact on pupil achievement. Addressing potential biases by using a difference-in-difference approach, I find that the test score gap is larger in classes where everybody gets homework than in classes…

  13. The Year of Secret Assignments

    ERIC Educational Resources Information Center

    Moriarty, Jaclyn

    2004-01-01

    The path to "novelist" was a convoluted one for Moriarty, who began writing fiction as doctoral student at Cambridge University. Her interest in young adults stems from an appreciation for the "troubles, strengths, and surprises of that age group." Now, in a uniquely formatted book titled "The Year of Secret Assignments," we peek inside the mind…

  14. Managing Large Volumes of Assignments

    ERIC Educational Resources Information Center

    Park, James; Hagen, John, Jr.

    2005-01-01

    In spring 2003, the Distance Education Network (DEN), Viterbi School of Engineering at the University of Southern California (USC), had 860 students and more than 1,000 enrollments in 70 courses toward 10 different degrees. Typically, for assignments in engineering courses, professors require students to show how their answers are derived so that…

  15. Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice Using a CRISPR/Cas9 System

    PubMed Central

    Li, Meiru; Li, Xiaoxia; Zhou, Zejiao; Wu, Pingzhi; Fang, Maichun; Pan, Xiaoping; Lin, Qiupeng; Luo, Wanbin; Wu, Guojiang; Li, Hongqing

    2016-01-01

    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated (Cas) systems have been successfully used as efficient tools for genome editing in a variety of species. We used the CRISPR/Cas9 system to mutate the Gn1a (Os01g0197700), DEP1 (Os09g0441900), GS3 (Os03g0407400), and IPA1 (Os08g0509600) genes of rice cultivar Zhonghua 11, genes which have been reported to function as regulators of grain number, panicle architecture, grain size and plant architecture, respectively. Analysis of the phenotypes and frequencies of edited genes in the first generation of transformed plants (T0) showed that the CRISPR/Cas9 system was highly efficient in inducing targeted gene editing, with the desired genes being edited in 42.5% (Gn1a), 67.5% (DEP1), 57.5% (GS3), and 27.5% (IPA1) of the transformed plants. The T2 generation of the gn1a, dep1, and gs3 mutants featured enhanced grain number, dense erect panicles, and larger grain size, respectively. Furthermore, semi-dwarf, and grain with long awn, phenotypes were observed in dep1 and gs3 mutants, respectively. The ipa1 mutants showed two contrasting phenotypes, having either fewer tillers or more tillers, depending on the changes induced in the OsmiR156 target region. In addition, we found that mutants with deletions occurred more frequently than previous reports had indicated and that off-targeting had taken place in highly similar target sequences. These results proved that multiple regulators of important traits can be modified in a single cultivar by CRISPR/Cas9, and thus facilitate the dissection of complex gene regulatory networks in the same genomic background and the stacking of important traits in cultivated varieties. PMID:27066031

  16. Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system

    SciTech Connect

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Deane, Janet E.; Birket, Susan; Picking, William D.; Blocker, Ariel; Picking, Wendy L.; Lea, Susan M.

    2006-09-01

    IpaD, the putative needle-tip protein of the S. flexneri type III secretion system, has been crystallized in a variety of crystal forms using in-drop proteolysis. Native and selenomethionine-labelled data collection and preliminary analyses are reported. IpaD, the putative needle-tip protein of the Shigella flexneri type III secretion system, has been overexpressed and purified. Crystals were grown of the native protein in space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 55.9, b = 100.7, c = 112.0 Å, and data were collected to 2.9 Å resolution. Analysis of the native Patterson map revealed a peak at 50% of the origin on the Harker section v = 0.5, suggesting twofold non-crystallographic symmetry parallel to the b crystallographic axis. As attempts to derivatize or grow selenomethionine-labelled protein crystals failed, in-drop proteolysis was used to produce new crystal forms. A trace amount of subtilisin Carlsberg was added to IpaD before sparse-matrix screening, resulting in the production of several new crystal forms. This approach produced SeMet-labelled crystals and diffraction data were collected to 3.2 Å resolution. The SeMet crystals belong to space group C2, with unit-cell parameters a = 139.4, b = 45.0, c = 99.5 Å, β = 107.9°. An anomalous difference Patterson map revealed peaks on the Harker section v = 0, while the self-rotation function indicates the presence of a twofold noncrystallographic symmetry axis, which is consistent with two molecules per asymmetric unit.

  17. Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice Using a CRISPR/Cas9 System.

    PubMed

    Li, Meiru; Li, Xiaoxia; Zhou, Zejiao; Wu, Pingzhi; Fang, Maichun; Pan, Xiaoping; Lin, Qiupeng; Luo, Wanbin; Wu, Guojiang; Li, Hongqing

    2016-01-01

    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated (Cas) systems have been successfully used as efficient tools for genome editing in a variety of species. We used the CRISPR/Cas9 system to mutate the Gn1a (Os01g0197700), DEP1 (Os09g0441900), GS3 (Os03g0407400), and IPA1 (Os08g0509600) genes of rice cultivar Zhonghua 11, genes which have been reported to function as regulators of grain number, panicle architecture, grain size and plant architecture, respectively. Analysis of the phenotypes and frequencies of edited genes in the first generation of transformed plants (T0) showed that the CRISPR/Cas9 system was highly efficient in inducing targeted gene editing, with the desired genes being edited in 42.5% (Gn1a), 67.5% (DEP1), 57.5% (GS3), and 27.5% (IPA1) of the transformed plants. The T2 generation of the gn1a, dep1, and gs3 mutants featured enhanced grain number, dense erect panicles, and larger grain size, respectively. Furthermore, semi-dwarf, and grain with long awn, phenotypes were observed in dep1 and gs3 mutants, respectively. The ipa1 mutants showed two contrasting phenotypes, having either fewer tillers or more tillers, depending on the changes induced in the OsmiR156 target region. In addition, we found that mutants with deletions occurred more frequently than previous reports had indicated and that off-targeting had taken place in highly similar target sequences. These results proved that multiple regulators of important traits can be modified in a single cultivar by CRISPR/Cas9, and thus facilitate the dissection of complex gene regulatory networks in the same genomic background and the stacking of important traits in cultivated varieties.

  18. Fleet Assignment Using Collective Intelligence

    NASA Technical Reports Server (NTRS)

    Antoine, Nicolas E.; Bieniawski, Stefan R.; Kroo, Ilan M.; Wolpert, David H.

    2004-01-01

    Product distribution theory is a new collective intelligence-based framework for analyzing and controlling distributed systems. Its usefulness in distributed stochastic optimization is illustrated here through an airline fleet assignment problem. This problem involves the allocation of aircraft to a set of flights legs in order to meet passenger demand, while satisfying a variety of linear and non-linear constraints. Over the course of the day, the routing of each aircraft is determined in order to minimize the number of required flights for a given fleet. The associated flow continuity and aircraft count constraints have led researchers to focus on obtaining quasi-optimal solutions, especially at larger scales. In this paper, the authors propose the application of this new stochastic optimization algorithm to a non-linear objective cold start fleet assignment problem. Results show that the optimizer can successfully solve such highly-constrained problems (130 variables, 184 constraints).

  19. Fleet Assignment Using Collective Intelligence

    NASA Technical Reports Server (NTRS)

    Antoine, Nicolas E.; Bieniawski, Stefan R.; Kroo, Ilan M.; Wolpert, David H.

    2004-01-01

    Airline fleet assignment involves the allocation of aircraft to a set of flights legs in order to meet passenger demand, while satisfying a variety of constraints. Over the course of the day, the routing of each aircraft is determined in order to minimize the number of required flights for a given fleet. The associated flow continuity and aircraft count constraints have led researchers to focus on obtaining quasi-optimal solutions, especially at larger scales. In this paper, the authors propose the application of an agent-based integer optimization algorithm to a "cold start" fleet assignment problem. Results show that the optimizer can successfully solve such highly- constrained problems (129 variables, 184 constraints).

  20. 5 CFR 870.901 - Assignments permitted.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) FEDERAL EMPLOYEES' GROUP LIFE INSURANCE PROGRAM Assignments of Life Insurance § 870.901..., and compensationers. (2) An individual may assign ownership of all life insurance under this part.../she must assign all the insurance; an individual cannot assign only a portion of the coverage....

  1. 31 CFR 306.76 - Fiduciaries acting as a unit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Fiduciaries acting as a unit. 306.76.... SECURITIES Assignments by or in Behalf of Trustees and Similar Fiduciaries § 306.76 Fiduciaries acting as a... to act as a unit for any public or private trust estate may be assigned for any...

  2. 31 CFR 306.76 - Fiduciaries acting as a unit.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Fiduciaries acting as a unit. 306.76.... SECURITIES Assignments by or in Behalf of Trustees and Similar Fiduciaries § 306.76 Fiduciaries acting as a... to act as a unit for any public or private trust estate may be assigned for any...

  3. Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system

    PubMed Central

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Deane, Janet E.; Birket, Susan; Picking, William D.; Blocker, Ariel; Picking, Wendy L.; Lea, Susan M.

    2006-01-01

    IpaD, the putative needle-tip protein of the Shigella flexneri type III secretion system, has been overexpressed and purified. Crystals were grown of the native protein in space group P212121, with unit-cell parameters a = 55.9, b = 100.7, c = 112.0 Å, and data were collected to 2.9 Å resolution. Analysis of the native Patterson map revealed a peak at 50% of the origin on the Harker section v = 0.5, suggesting twofold non-crystallographic symmetry parallel to the b crystallographic axis. As attempts to derivatize or grow selenomethionine-labelled protein crystals failed, in-drop proteolysis was used to produce new crystal forms. A trace amount of subtilisin Carlsberg was added to IpaD before sparse-matrix screening, resulting in the production of several new crystal forms. This approach produced SeMet-labelled crystals and diffraction data were collected to 3.2 Å resolution. The SeMet crystals belong to space group C2, with unit-cell parameters a = 139.4, b = 45.0, c = 99.5 Å, β = 107.9°. An anomalous difference Patterson map revealed peaks on the Harker section v = 0, while the self-rotation function indicates the presence of a twofold noncrystallographic symmetry axis, which is consistent with two molecules per asymmetric unit. PMID:16946465

  4. 20 CFR 10.423 - May compensation payments be assigned to, or attached by, creditors?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... beneficiary to assign his or her claim is null and void. However, pursuant to provisions of the Social Security Act, 42 U.S.C. 659, and regulations issued by the Office of Personnel Management (OPM) at 5...

  5. 20 CFR 10.423 - May compensation payments be assigned to, or attached by, creditors?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... beneficiary to assign his or her claim is null and void. However, pursuant to provisions of the Social Security Act, 42 U.S.C. 659, and regulations issued by the Office of Personnel Management (OPM) at 5...

  6. Vibrational assignments of 2-iodopyridine

    NASA Astrophysics Data System (ADS)

    Sortur, Veenasangeeta; Yenagi, Jayashree; Tonannavar, J.

    2008-02-01

    A review of the vibrational assignments for 2-iodopyridine has been proposed based on the FT-Raman (3500-50 cm -1) and IR (4000-400 cm -1) spectral measurements. Equilibrium geometries and vibrational frequencies have been computed from a variety of electronic structure methods: the ab initio (RHF), six DFT (BLYP, BP86, B3LYP, B3P86, B3PW91 and SVWN) and MP2 methods using 3-21G*, LANL2DZ and DGDZVP basis sets. A normal coordinate analysis has been carried out: the normal modes and their couplings are characterized in terms of potential energy distributions (PEDs). The comparison of assignments for pyridine and halopyridines shows that several of the normal modes arise from coupled vibrations in 2-iodopyridine. The BP86 and B3LYP methods with LANL2DZ basis set have performed reasonably well in reproducing the observed spectra, demonstrating that the LANL2DZ basis set (with effective core potential representations of electrons near the nuclei for post-third row atoms) is suitable for 2-iodopyridine.

  7. Assignment Choice, Effort, and Assignment Completion: Does Work Ethic Predict Those Who Choose Higher-Effort Assignments?

    ERIC Educational Resources Information Center

    Parkhurst, John T.; Fleisher, Matthew S.; Skinner, Christopher H.; Woehr, David J.; Hawthorn-Embree, Meredith L.

    2011-01-01

    After completing the Multidimensional Work-Ethic Profile (MWEP), 98 college students were given a 20-problem math computation assignment and instructed to stop working on the assignment after completing 10 problems. Next, they were allowed to choose to finish either the partially completed assignment that had 10 problems remaining or a new…

  8. The Mechanism Design Approach to Student Assignment

    ERIC Educational Resources Information Center

    Pathak, Parag A.

    2011-01-01

    The mechanism design approach to student assignment involves the theoretical, empirical, and experimental study of systems used to allocate students into schools around the world. Recent practical experience designing systems for student assignment has raised new theoretical questions for the theory of matching and assignment. This article reviews…

  9. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused...

  10. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused...

  11. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused...

  12. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused...

  13. Assigning Homework to Couples and Families

    ERIC Educational Resources Information Center

    Dattilio, Frank M.; Dickson, Jan

    2007-01-01

    Homework assignments, or "out-of-session assignments," have gained popularity among couple and family therapists due to their potential to solidify the work achieved during the course of therapy and to help clients take responsibility for their own change. Homework assignments also serve as a testing ground in therapy to determine what works and…

  14. 7 CFR 1437.104 - Assigned production.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Assigned production. 1437.104 Section 1437.104... Determining Yield Coverage Using Actual Production History § 1437.104 Assigned production. (a) When determining losses under this section, assigned production will be used to offset the loss of production...

  15. 31 CFR 337.5 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Assignments. 337.5 Section 337.5... ADMINISTRATION DEBENTURES Certificated Debentures § 337.5 Assignments. (a) If the registered payee, or an assignee holding a certificated debenture under proper assignment from the registered payee, desires...

  16. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Work assignments. 548.17 Section 548.17... PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the religious tenets of an inmate's faith are violated or jeopardized by a particular work assignment,...

  17. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Work assignments. 548.17 Section 548.17... PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the religious tenets of an inmate's faith are violated or jeopardized by a particular work assignment,...

  18. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Work assignments. 548.17 Section 548.17... PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the religious tenets of an inmate's faith are violated or jeopardized by a particular work assignment,...

  19. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Work assignments. 548.17 Section 548.17... PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the religious tenets of an inmate's faith are violated or jeopardized by a particular work assignment,...

  20. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Work assignments. 548.17 Section 548.17... PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the religious tenets of an inmate's faith are violated or jeopardized by a particular work assignment,...

  1. 47 CFR 74.802 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Frequency assignment. 74.802 Section 74.802... Frequency assignment. (a) Frequencies within the following bands may be assigned for use by low power... MHz. All zones 113 km (70 miles) (c) Specific frequency operation is required when operating...

  2. 47 CFR 74.802 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignment. 74.802 Section 74.802... Frequency assignment. (a) Frequencies within the following bands may be assigned for use by low power... MHz. All zones 113 km (70 miles) (c) Specific frequency operation is required when operating...

  3. 47 CFR 80.509 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Frequency assignment. 80.509 Section 80.509... MARITIME SERVICES Private Coast Stations and Marine Utility Stations § 80.509 Frequency assignment. Frequencies assignable to private coast stations and marine utility stations are listed in subpart H....

  4. 47 CFR 74.802 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignment. 74.802 Section 74.802... Frequency assignment. (a) Frequencies within the following bands may be assigned for use by low power... MHz. All zones 113 km (70 miles) (c) Specific frequency operation is required when operating...

  5. 47 CFR 80.509 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Frequency assignment. 80.509 Section 80.509... MARITIME SERVICES Private Coast Stations and Marine Utility Stations § 80.509 Frequency assignment. Frequencies assignable to private coast stations and marine utility stations are listed in subpart H....

  6. 47 CFR 80.509 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Frequency assignment. 80.509 Section 80.509... MARITIME SERVICES Private Coast Stations and Marine Utility Stations § 80.509 Frequency assignment. Frequencies assignable to private coast stations and marine utility stations are listed in subpart H....

  7. 47 CFR 80.509 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Frequency assignment. 80.509 Section 80.509... MARITIME SERVICES Private Coast Stations and Marine Utility Stations § 80.509 Frequency assignment. Frequencies assignable to private coast stations and marine utility stations are listed in subpart H....

  8. 47 CFR 80.509 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Frequency assignment. 80.509 Section 80.509... MARITIME SERVICES Private Coast Stations and Marine Utility Stations § 80.509 Frequency assignment. Frequencies assignable to private coast stations and marine utility stations are listed in subpart H....

  9. 47 CFR 74.802 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignment. 74.802 Section 74.802... Frequency assignment. (a) Frequencies within the following bands may be assigned for use by low power... MHz. All zones 113 km (70 miles) (c) Specific frequency operation is required when operating...

  10. Lexical Stress Assignment in Italian Developmental Dyslexia

    ERIC Educational Resources Information Center

    Paizi, Despina; Zoccolotti, Pierluigi; Burani, Cristina

    2011-01-01

    Stress assignment to Italian polysyllabic words is unpredictable, because stress is neither marked nor predicted by rule. Stress assignment, especially to low frequency words, has been reported to be a function of stress dominance and stress neighbourhood. Two experiments investigate stress assignment in sixth-grade, skilled and dyslexic, readers.…

  11. [IPA secretary and patron--Freud's patient, financial administrator and friend. Anton von Freund's letters to Sigmund Freud (1916-1919)].

    PubMed

    Huppke, Andrea; Schröter, Michael

    2011-01-01

    Although the letters, of which numerous and lengthy excerpts are presented in this paper, have repeatedly been used by scholars, they have so far remained unpublished. There are 45 items, written between 4. 1. 1916 and 13. 7. 1919. They indicate a passionate transference to Freud, unfolding against the background of two Hungarian revolutions. After suffering a relapse of his cancer, v. Freund had several stretches of analysis with Freud. While he was better, he established two major funds: one of them allowing the foundation of the psychoanalytic publishing house, the other destined to sponsor a psychoanalytic clinic in Budapest. V. Freund helped organize the Budapest IPA congress, became a member of the "secret committee" and started to actively conduct analyses. Freud was very attached to him and felt deeply shaken by the inexorable progression of v. Freund's disease and then death in January 1920.

  12. Integrated assignment and path planning

    NASA Astrophysics Data System (ADS)

    Murphey, Robert A.

    2005-11-01

    A surge of interest in unmanned systems has exposed many new and challenging research problems across many fields of engineering and mathematics. These systems have the potential of transforming our society by replacing dangerous and dirty jobs with networks of moving machines. This vision is fundamentally separate from the modern view of robotics in that sophisticated behavior is realizable not by increasing individual vehicle complexity, but instead through collaborative teaming that relies on collective perception, abstraction, decision making, and manipulation. Obvious examples where collective robotics will make an impact include planetary exploration, space structure assembly, remote and undersea mining, hazardous material handling and clean-up, and search and rescue. Nonetheless, the phenomenon driving this technology trend is the increasing reliance of the US military on unmanned vehicles, specifically, aircraft. Only a few years ago, following years of resistance to the use of unmanned systems, the military and civilian leadership in the United States reversed itself and have recently demonstrated surprisingly broad acceptance of increasingly pervasive use of unmanned platforms in defense surveillance, and even attack. However, as rapidly as unmanned systems have gained acceptance, the defense research community has discovered the technical pitfalls that lie ahead, especially for operating collective groups of unmanned platforms. A great deal of talent and energy has been devoted to solving these technical problems, which tend to fall into two categories: resource allocation of vehicles to objectives, and path planning of vehicle trajectories. An extensive amount of research has been conducted in each direction, yet, surprisingly, very little work has considered the integrated problem of assignment and path planning. This dissertation presents a framework for studying integrated assignment and path planning and then moves on to suggest an exact

  13. Library-Based Assignments That Enrich the Business Communication Course.

    ERIC Educational Resources Information Center

    Hiemstra, Kathleen M.

    2002-01-01

    Reviews the benefits of library work (and some cautions) before describing four assignments that exploit library resources: a business report assignment; a professional journal assignment; a style manual format assignment; and an international business communication assignment. (SG)

  14. 16 CFR 301.40 - Item number or mark to be assigned to each fur product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... fur product. 301.40 Section 301.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.40 Item number or mark to be assigned to each fur product. (a) For the purpose of identification, each...

  15. 16 CFR 301.40 - Item number or mark to be assigned to each fur product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... fur product. 301.40 Section 301.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.40 Item number or mark to be assigned to each fur product. (a) For the purpose of identification, each...

  16. 16 CFR 301.40 - Item number or mark to be assigned to each fur product.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... fur product. 301.40 Section 301.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.40 Item number or mark to be assigned to each fur product. (a) For the purpose of identification, each...

  17. 16 CFR 301.40 - Item number or mark to be assigned to each fur product.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... fur product. 301.40 Section 301.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.40 Item number or mark to be assigned to each fur product. (a) For the purpose of identification, each...

  18. 16 CFR 301.40 - Item number or mark to be assigned to each fur product.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... fur product. 301.40 Section 301.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER FUR PRODUCTS LABELING ACT Regulations § 301.40 Item number or mark to be assigned to each fur product. (a) For the purpose of identification, each...

  19. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of Government-assigned serial numbers. It is DoD policy that contractors apply Government-assigned serial numbers, such as tail... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Policy for assignment...

  20. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of Government-assigned serial numbers. It is DoD policy that contractors apply Government-assigned serial numbers, such as tail... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Policy for assignment...

  1. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of Government-assigned serial numbers. It is DoD policy that contractors apply Government-assigned serial numbers, such as tail... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy for assignment...

  2. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of Government-assigned serial numbers. It is DoD policy that contractors apply Government-assigned serial numbers, such as tail... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Policy for assignment...

  3. 48 CFR 211.274-5 - Policy for assignment of Government-assigned serial numbers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Using and Maintaining Requirements Documents 211.274-5 Policy for assignment of Government-assigned serial numbers. It is DoD policy that contractors apply Government-assigned serial numbers, such as tail... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Policy for assignment...

  4. An Investigation of the Partial-Assignment Completion Effect on Students' Assignment Choice Behavior

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Skinner, Christopher H.; Parkhurst, John; Conley, Elisha

    2011-01-01

    This study was designed to investigate the partial assignment completion effect. Seventh-grade students were given a math assignment. After working for 5 min, they were interrupted and their partially completed assignments were collected. About 20 min later, students were given their partially completed assignment and a new, control assignment…

  5. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator...

  6. Absolute Points for Multiple Assignment Problems

    ERIC Educational Resources Information Center

    Adlakha, V.; Kowalski, K.

    2006-01-01

    An algorithm is presented to solve multiple assignment problems in which a cost is incurred only when an assignment is made at a given cell. The proposed method recursively searches for single/group absolute points to identify cells that must be loaded in any optimal solution. Unlike other methods, the first solution is the optimal solution. The…

  7. Scaling Preference Data for Program Assignments.

    ERIC Educational Resources Information Center

    Carifio, James

    The present study devised a computerized assignment-by-preference algorithm for a ninth-grade exploratory curriculum. The problem addressed was one of maximally mapping all students into 8 of 12 vocational programs in terms of their preferences for studying each of the programs and the assignment restrictions established by the school. To minimize…

  8. 25 CFR 214.18 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Assignments. 214.18 Section 214.18 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF OSAGE RESERVATION LANDS, OKLAHOMA, FOR MINING, EXCEPT OIL AND GAS § 214.18 Assignments. Approved leases or any interest therein...

  9. 25 CFR 214.18 - Assignments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Assignments. 214.18 Section 214.18 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF OSAGE RESERVATION LANDS, OKLAHOMA, FOR MINING, EXCEPT OIL AND GAS § 214.18 Assignments. Approved leases or any interest therein...

  10. 25 CFR 214.18 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Assignments. 214.18 Section 214.18 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF OSAGE RESERVATION LANDS, OKLAHOMA, FOR MINING, EXCEPT OIL AND GAS § 214.18 Assignments. Approved leases or any interest therein...

  11. 25 CFR 214.18 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Assignments. 214.18 Section 214.18 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF OSAGE RESERVATION LANDS, OKLAHOMA, FOR MINING, EXCEPT OIL AND GAS § 214.18 Assignments. Approved leases or any interest therein...

  12. Using Cognitive Science to Assign Test Weights.

    ERIC Educational Resources Information Center

    Bhaskar, R.; Dillard, Jesse F.

    1983-01-01

    Description of an objective method for assigning weights to questions on examinations includes discussions of classical test theory, knowledge organization, and how task analysis can be used to identify knowledge elements required to solve specific problems, rank them, and assign objective weights to exam questions using a Pareto distribution (7…

  13. 32 CFR 241.3 - Assignment authority.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.3 Assignment authority. The Secretary of Defense may with the agreement, of the private sector organization concerned, arrange for the temporary assignment of a DoD employee to a private sector organization or accept...

  14. Detecting Plagiarism in MS Access Assignments

    ERIC Educational Resources Information Center

    Singh, Anil

    2013-01-01

    Assurance of individual effort from students in computer-based assignments is a challenge. Due to digitization, students can easily use a copy of their friend's work and submit it as their own. Plagiarism in assignments puts students who cheat at par with those who work honestly and this compromises the learning evaluation process. Using a…

  15. 7 CFR 623.19 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Assignments. 623.19 Section 623.19 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES EMERGENCY WETLANDS RESERVE PROGRAM § 623.19 Assignments. Any participant...

  16. 7 CFR 1467.17 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1467.17 Section 1467.17 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS WETLANDS RESERVE PROGRAM § 1467.17 Assignments. Any...

  17. Effects of Individualized Assignments on Biology Achievement.

    ERIC Educational Resources Information Center

    Kremer, Philip L.

    1983-01-01

    Compared detailed (favoring field dependence and induction) and nondetailed (favoring field dependence and deduction) assignments on biology achievement of grade 10 male students (N=95) over a seven-month period. Detailed assignments, employing pictorial and verbal block diagrams and high structure, significantly enhanced learning among some…

  18. 7 CFR 623.19 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Assignments. 623.19 Section 623.19 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES EMERGENCY WETLANDS RESERVE PROGRAM § 623.19 Assignments. Any participant...

  19. 7 CFR 625.17 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Assignments. 625.17 Section 625.17 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE WATER RESOURCES HEALTHY FORESTS RESERVE PROGRAM § 625.17 Assignments. Any person entitled to...

  20. 33 CFR 401.61 - Assigned frequencies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Assigned frequencies. 401.61 Section 401.61 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT... frequencies. The Seaway stations operate on the following assigned VHF frequencies: 156.8 MHz—(channel...

  1. 33 CFR 401.61 - Assigned frequencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Assigned frequencies. 401.61 Section 401.61 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT... frequencies. The Seaway stations operate on the following assigned VHF frequencies: 156.8 MHz—(channel...

  2. 33 CFR 401.61 - Assigned frequencies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Assigned frequencies. 401.61 Section 401.61 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT... frequencies. The Seaway stations operate on the following assigned VHF frequencies: 156.8 MHz—(channel...

  3. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Frequency assignment. 74.1202 Section 74.1202... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... stations. The application must be specific with regard to the frequency requested. Only one output...

  4. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... channel. Editorial Note: For Federal Register citations affecting § 78.18, see the List of CFR Sections... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service...

  5. 47 CFR 74.103 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignment. 74.103 Section 74.103....103 Frequency assignment. (a) Frequencies allocated to broadcasting and the various categories of auxiliary stations, in the FCC's Table of Frequency Allocations (Part 2 of this chapter), may be...

  6. 47 CFR 74.502 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignment. 74.502 Section 74.502... § 74.502 Frequency assignment. (a) Except as provided in NG30, broadcast auxiliary stations licensed as... Frequency Allocations. These stations will be protected from possible interference caused by new users...

  7. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Frequency assignment. 74.402 Section 74.402....402 Frequency assignment. Operation on all channels listed in this section (except: frequencies 26.07 MHz, 26.11 MHz, and 26.45 MHz, and frequencies listed in paragraphs (a)(4) and (c)(1) of this...

  8. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Frequency assignment. 74.1202 Section 74.1202... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... stations. The application must be specific with regard to the frequency requested. Only one output...

  9. 47 CFR 74.103 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Frequency assignment. 74.103 Section 74.103....103 Frequency assignment. (a) Frequencies allocated to broadcasting and the various categories of auxiliary stations, in the FCC's Table of Frequency Allocations (Part 2 of this chapter), may be...

  10. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignment. 74.1202 Section 74.1202... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... stations. The application must be specific with regard to the frequency requested. Only one output...

  11. 47 CFR 74.502 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignment. 74.502 Section 74.502... § 74.502 Frequency assignment. (a) Except as provided in NG30, broadcast auxiliary stations licensed as... Frequency Allocations. These stations will be protected from possible interference caused by new users...

  12. 33 CFR 401.61 - Assigned frequencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Assigned frequencies. 401.61 Section 401.61 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT... frequencies. The Seaway stations operate on the following assigned VHF frequencies: 156.8 MHz—(channel...

  13. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignment. 74.1202 Section 74.1202... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... stations. The application must be specific with regard to the frequency requested. Only one output...

  14. 47 CFR 74.502 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignment. 74.502 Section 74.502... § 74.502 Frequency assignment. (a) Except as provided in NG30, broadcast auxiliary stations licensed as... Frequency Allocations. These stations will be protected from possible interference caused by new users...

  15. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignment. 74.402 Section 74.402....402 Frequency assignment. Operation on all channels listed in this section (except: frequencies 26.07 MHz, 26.11 MHz, and 26.45 MHz, and frequencies listed in paragraphs (a)(4) and (c)(1) of this...

  16. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignment. 74.1202 Section 74.1202... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... stations. The application must be specific with regard to the frequency requested. Only one output...

  17. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... channel. Editorial Note: For Federal Register citations affecting § 78.18, see the List of CFR Sections... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service...

  18. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignment. 74.402 Section 74.402....402 Frequency assignment. Operation on all channels listed in this section (except: frequencies 26.07 MHz, 26.11 MHz, and 26.45 MHz, and frequencies listed in paragraphs (a)(4) and (c)(1) of this...

  19. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignment. 74.402 Section 74.402....402 Frequency assignment. Operation on all channels listed in this section (except: frequencies 26.07 MHz, 26.11 MHz, and 26.45 MHz, and frequencies listed in paragraphs (a)(4) and (c)(1) of this...

  20. 47 CFR 74.103 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Frequency assignment. 74.103 Section 74.103....103 Frequency assignment. (a) Frequencies allocated to broadcasting and the various categories of auxiliary stations, in the FCC's Table of Frequency Allocations (Part 2 of this chapter), may be...

  1. 33 CFR 401.61 - Assigned frequencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Assigned frequencies. 401.61 Section 401.61 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT... frequencies. The Seaway stations operate on the following assigned VHF frequencies: 156.8 MHz—(channel...

  2. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Frequency assignment. 74.402 Section 74.402....402 Frequency assignment. Operation on all channels listed in this section (except: frequencies 26.07 MHz, 26.11 MHz, and 26.45 MHz, and frequencies listed in paragraphs (a)(4) and (c)(1) of this...

  3. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator...

  4. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator...

  5. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator...

  6. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator...

  7. Individualized Assignments in an Experimental Psychology Course.

    ERIC Educational Resources Information Center

    Hovancik, John R.

    1984-01-01

    A computer is used to individualize student assignments in statistics. The principal benefit of individualized activities is that they emphasize decision-making processes rather than correct answers. Students in an individualized assignment group scored higher on an examination than those in a comparison group. (RM)

  8. Online Discussion Assignments Improve Students' Class Preparation

    ERIC Educational Resources Information Center

    Lineweaver, Tara T.

    2010-01-01

    To increase the number of students who read the text before class and to promote student interaction centering on text material, I developed an online discussion assignment as a required component of a cognitive psychology course. Across 2 studies, this assignment had a limited effect on examination performance, but students completing online…

  9. Using Guided Assignments To Teach Literature.

    ERIC Educational Resources Information Center

    Beach, Richard; And Others

    This document provides a rationale (theory) and some models (application) to help secondary teachers develop their own "guided assignments"--road maps which offer young readers structured assistance in reading literature. The guide's first section provides a theoretical framework and blueprint for guided assignments. It begins by explaining the…

  10. Stress Assignment in Reading Italian Polysyllabic Pseudowords

    ERIC Educational Resources Information Center

    Sulpizio, Simone; Arduino, Lisa S.; Paizi, Despina; Burani, Cristina

    2013-01-01

    In 4 naming experiments we investigated how Italian readers assign stress to pseudowords. We assessed whether participants assign stress following distributional information such as stress neighborhood (the proportion and number of existent words sharing orthographic ending and stress pattern) and whether such distributional information affects…

  11. 7 CFR 1415.16 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Assignments. 1415.16 Section 1415.16 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS GRASSLANDS RESERVE PROGRAM § 1415.16 Assignments. (a)...

  12. 7 CFR 1415.16 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Assignments. 1415.16 Section 1415.16 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS GRASSLANDS RESERVE PROGRAM § 1415.16 Assignments. (a)...

  13. 7 CFR 1415.16 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Assignments. 1415.16 Section 1415.16 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS GRASSLANDS RESERVE PROGRAM § 1415.16 Assignments. (a)...

  14. 7 CFR 1415.16 - Assignments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Assignments. 1415.16 Section 1415.16 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS GRASSLANDS RESERVE PROGRAM § 1415.16 Assignments. (a)...

  15. 7 CFR 1415.16 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1415.16 Section 1415.16 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS GRASSLANDS RESERVE PROGRAM § 1415.16 Assignments. (a)...

  16. 37 CFR 3.56 - Conditional assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Conditional assignments. 3.56 Section 3.56 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording §...

  17. 37 CFR 3.56 - Conditional assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Conditional assignments. 3.56 Section 3.56 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording §...

  18. 37 CFR 3.56 - Conditional assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Conditional assignments. 3.56 Section 3.56 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording §...

  19. 37 CFR 3.56 - Conditional assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Conditional assignments. 3.56 Section 3.56 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording §...

  20. 37 CFR 3.56 - Conditional assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Conditional assignments. 3.56 Section 3.56 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording §...

  1. An Individualized Observation Assignment in Professional Preparation.

    ERIC Educational Resources Information Center

    Chapman, Nancy L.

    This paper describes an assignment designed to improve undergraduate physical education students' observational skills through skill analysis in volleyball. Early in the term, students are videotaped while performing two major volleyball skills. After several weeks of instruction on various volleyball skills, students complete the assignment which…

  2. Gapminder: An AP Human Geography Lab Assignment

    ERIC Educational Resources Information Center

    Keller, Kenneth H.

    2012-01-01

    This lesson is designed as a lab assignment for Advanced Placement (AP) Human Geography students wherein they use the popular Gapminder web site to compare levels of development in countries from different world regions. For this lesson, it is important for the teacher to practice with Gapminder before giving the assignment to students. (Contains…

  3. Juggling Act

    ERIC Educational Resources Information Center

    Rudalevige, Andrew

    2009-01-01

    Two education bills from George W. Bush's first term are long overdue for reauthorization. One, of course, is the No Child Left Behind Act (NCLB), passed in late 2001. The other is the Education Sciences Reform Act (ESRA), which in November 2002 replaced the Office of Educational Research and Improvement (OERI) with a new Institute of Education…

  4. Root produced DHZR-, ZR- and IPA-like cytokinins in xylem sap in relation to coppice shoot initiation and growth in cloned trees of Betula pubescens.

    PubMed

    Rinne, P; Saarelainen, A

    1994-10-01

    Six-year-old cloned Betula pubescens Ehrh. trees, grown outdoors at 65 degrees 01' N, were cut on six dates during the growing season to study coppice shoot development in relation to root-produced cytokinin-like compounds. Bleeding sap was collected over timed intervals for two days after cutting, and endogenous cytokinin-like compounds were measured by ELISA assay in HPLC-purified fractions of xylem sap. Initiation and development of coppice shoots on the clonally propagated plants were comparable to those in seedlings. Coppice shoot initiation was affected by the time of cutting, diminishing significantly after June. Of the cytokinin-like compounds detected in the xylem sap, zeatin riboside-like (ZR) compounds were present in the highest concentrations, and the concentrations of dihydrozeatin riboside-like (DHZR) and isopentenyladenoside-like (IPA) compounds were approximately one third and one eighth of the ZR concentrations, respectively. The concentration of cytokinin-like compounds was positively correlated with xylem sap flow rate. The export of cytokinin-like compounds, especially DHZR- and ZR-types, was positively correlated with the initiation and elongation rate of coppice shoots, the number of lateral branches, and the radial growth of the more slowly growing coppice shoots. The export of cytokinin-like compounds collected immediately after cutting may represent the basal value for each tree. This value is probably affected by the size and activity of the root system and may be a relevant estimate for predicting the success of coppicing.

  5. Optimal processor assignment for pipeline computations

    NASA Technical Reports Server (NTRS)

    Nicol, David M.; Simha, Rahul; Choudhury, Alok N.; Narahari, Bhagirath

    1991-01-01

    The availability of large scale multitasked parallel architectures introduces the following processor assignment problem for pipelined computations. Given a set of tasks and their precedence constraints, along with their experimentally determined individual responses times for different processor sizes, find an assignment of processor to tasks. Two objectives are of interest: minimal response given a throughput requirement, and maximal throughput given a response time requirement. These assignment problems differ considerably from the classical mapping problem in which several tasks share a processor; instead, it is assumed that a large number of processors are to be assigned to a relatively small number of tasks. Efficient assignment algorithms were developed for different classes of task structures. For a p processor system and a series parallel precedence graph with n constituent tasks, an O(np2) algorithm is provided that finds the optimal assignment for the response time optimization problem; it was found that the assignment optimizing the constrained throughput in O(np2log p) time. Special cases of linear, independent, and tree graphs are also considered.

  6. Automated Assignment of Proposals to Reviewers

    NASA Technical Reports Server (NTRS)

    Kantak, Anil; Kantak, Anil

    2006-01-01

    A computer program automates the process of selecting unbiased peer reviewers of research proposals submitted to NASA. Heretofore, such selection has been performed by manual searching of two large databases subject to a set of assignment rules. One database lists proposals and proposers; the other database lists potential reviewers. The manual search takes an average of several weeks per proposal. In contrast, the present software can perform the selection in seconds. The program begins by selecting one entry from each database, then applying the assignment rules to this pair of entries. If and only if all the assignment rules are satisfied, the chosen reviewer is assigned to the chosen proposal. The assignment rules enforced by the program are (1) a maximum allowable number of proposals assigned to a single reviewer; (2) a maximum allowable number of reviewers assigned to a single proposal; (3) if the proposing team includes a member affiliated with an industry, then the reviewer must not be affiliated with any industry; and (4) the reviewer must not be a member of the proposing team or affiliated with the same institution as that of a member of the proposing team.

  7. 20 CFR 332.6 - Standing by for and laying over between regularly assigned trips or tours of duty.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT MILEAGE OR WORK RESTRICTIONS AND STAND-BY OR LAY-OVER RULES § 332.6 Standing by for and laying over between regularly assigned trips or tours of...

  8. 42 CFR 23.7 - What must an entity agree to do before the assignment is made?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES PERSONNEL NATIONAL HEALTH SERVICE CORPS Assignment of National Health Service Corps Personnel § 23... purposes of section 334 of the Act, each National Health Service Corps site must enter into an agreement... provided by assigned National Health Service Corps personnel; (2) Take reasonable......

  9. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... Who Are Using a Ticket The Extension Period § 411.220 What if my ticket is no longer assigned to an EN or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an...

  10. 20 CFR 670.460 - What restrictions are there on the assignment of eligible applicants for nonresidential...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of eligible applicants for nonresidential enrollment in Job Corps? 670.460 Section 670.460 Employees... WORKFORCE INVESTMENT ACT Recruitment, Eligibility, Screening, Selection and Assignment, and Enrollment § 670.460 What restrictions are there on the assignment of eligible applicants for nonresidential...

  11. 31 CFR 306.40 - Execution of assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the presence of an individual authorized to certify assignments. All assignments must be made on the... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Execution of assignments. 306.40.... SECURITIES Assignments of Registered Securities-General § 306.40 Execution of assignments. The assignment...

  12. ACT Test

    MedlinePlus

    ... this page helpful? Also known as: ACT; Activated Coagulation Time Formal name: Activated Clotting Time Related tests: ... in the blood called platelets and proteins called coagulation factors are activated in a sequence of steps ...

  13. Acting Atoms.

    ERIC Educational Resources Information Center

    Farin, Susan Archie

    1997-01-01

    Describes a fun game in which students act as electrons, protons, and neutrons. This activity is designed to help students develop a concrete understanding of the abstract concept of atomic structure. (DKM)

  14. A New Gimmick for Assigning Absolute Configuration.

    ERIC Educational Resources Information Center

    Ayorinde, F. O.

    1983-01-01

    A five-step procedure is provided to help students in making the assignment absolute configuration less bothersome. Examples for both single (2-butanol) and multi-chiral carbon (3-chloro-2-butanol) molecules are included. (JN)

  15. Shakespearean Drama: A Pair of Writing Assignments.

    ERIC Educational Resources Information Center

    Kory, Fern

    1996-01-01

    Describes two writing assignments that may be used to make Shakespeare more approachable and understandable: first a paraphrase of a passage, and second a memo to an actor interpreting the same passage. (TB)

  16. Quantum probability assignment limited by relativistic causality

    PubMed Central

    Han, Yeong Deok; Choi, Taeseung

    2016-01-01

    Quantum theory has nonlocal correlations, which bothered Einstein, but found to satisfy relativistic causality. Correlation for a shared quantum state manifests itself, in the standard quantum framework, by joint probability distributions that can be obtained by applying state reduction and probability assignment that is called Born rule. Quantum correlations, which show nonlocality when the shared state has an entanglement, can be changed if we apply different probability assignment rule. As a result, the amount of nonlocality in quantum correlation will be changed. The issue is whether the change of the rule of quantum probability assignment breaks relativistic causality. We have shown that Born rule on quantum measurement is derived by requiring relativistic causality condition. This shows how the relativistic causality limits the upper bound of quantum nonlocality through quantum probability assignment. PMID:26971717

  17. 12 CFR 345.28 - Assigned ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... been considered as part of the bank's lending performance. In connection with any type of lending... Procedures Act; and (v) Violations of the Truth in Lending Act provisions regarding a consumer's right...

  18. 12 CFR 25.28 - Assigned ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... connection with any type of lending activity described in § 25.22(a), evidence of discriminatory or other... Settlement Procedures Act; and (v) Violations of the Truth in Lending Act provisions regarding a...

  19. Unifying Temporal and Structural Credit Assignment Problems

    NASA Technical Reports Server (NTRS)

    Agogino, Adrian K.; Tumer, Kagan

    2004-01-01

    Single-agent reinforcement learners in time-extended domains and multi-agent systems share a common dilemma known as the credit assignment problem. Multi-agent systems have the structural credit assignment problem of determining the contributions of a particular agent to a common task. Instead, time-extended single-agent systems have the temporal credit assignment problem of determining the contribution of a particular action to the quality of the full sequence of actions. Traditionally these two problems are considered different and are handled in separate ways. In this article we show how these two forms of the credit assignment problem are equivalent. In this unified frame-work, a single-agent Markov decision process can be broken down into a single-time-step multi-agent process. Furthermore we show that Monte-Carlo estimation or Q-learning (depending on whether the values of resulting actions in the episode are known at the time of learning) are equivalent to different agent utility functions in a multi-agent system. This equivalence shows how an often neglected issue in multi-agent systems is equivalent to a well-known deficiency in multi-time-step learning and lays the basis for solving time-extended multi-agent problems, where both credit assignment problems are present.

  20. Stress assignment in reading Italian polysyllabic pseudowords.

    PubMed

    Sulpizio, Simone; Arduino, Lisa S; Paizi, Despina; Burani, Cristina

    2013-01-01

    In 4 naming experiments we investigated how Italian readers assign stress to pseudowords. We assessed whether participants assign stress following distributional information such as stress neighborhood (the proportion and number of existent words sharing orthographic ending and stress pattern) and whether such distributional information affects naming speed. Experiments 1 and 2 tested how readers assign stress to pseudowords. The results showed that participants assign stress on the basis of the pseudowords' stress neighborhood, but only when this orthographic/phonological information is widely represented in the lexicon. Experiments 3 and 4 tested the naming speed of pseudowords with different stress patterns. Participants were faster in reading pseudowords with antepenultimate than with penultimate stress. The effect was not driven by distributional information, but it was related to the stage of articulation planning. Overall, the experiments showed that, under certain conditions, readers assign stress using orthographic/phonological distributional information. However, the distributional information does not speed up pseudoword naming, which is affected by stress computation at the level of the articulation planning of the stimulus. It is claimed that models of reading aloud and speech production should be merged at the level of phonological encoding, when segmental and metrical information are assembled and articulation is planned.

  1. 5 CFR 870.902 - Making an assignment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) FEDERAL EMPLOYEES' GROUP LIFE INSURANCE PROGRAM Assignments of Life Insurance § 870.902 Making an assignment. (a) To assign insurance, an insured individual must complete an approved assignment form. Only... intent to irrevocably assign all ownership of the insurance. The form must also be witnessed and...

  2. Medicare Accountable Care Organizations: Beneficiary Assignment Update.

    PubMed

    Vaughn, Thomas; MacKinney, A Clinton; Mueller, Keith J; Ullrich, Fred; Zhu, Xi

    2016-06-01

    This brief updates Brief No. 2014-3 and explains changes in the Centers for Medicare & Medicaid Services (CMS) Accountable Care Organization (ACO) regulations issued in June 2015 pertaining to beneficiary assignment for Medicare Shared Savings Program ACOs. Overall, the regulatory changes are intended to (1) encourage ACOs to participate in two-sided risk contracts, (2) increase the likelihood that beneficiaries are assigned to the physician (and ACO) from whom they receive most of their primary care services, and (3) make it easier for Federally Qualified Health Centers (FQHCs) and Rural Health Clinics (RHCs) to participate in ACOs. Understanding ACO beneficiary assignment policies is critical for ACO in managing their panel of ACO providers and beneficiaries. PMID:27416650

  3. From course assignment paper to publishable manuscript.

    PubMed

    Rew, Lynn

    2012-12-01

    Both undergraduate and graduate nursing students are expected to write numerous papers in their educational programs; however, most of these papers are never published. Many students and faculty lack the skills needed to convert a course assignment paper to a publishable manuscript. The purpose of this article is to describe 10 steps that can transform a course assignment paper into a publishable manuscript. These steps include outlining, clarifying the topic, clearly stating the purpose, identifying an appropriate audience, revising with faculty's feedback, querying journal editors, revising to conform to journal's author guidelines, requesting and responding to peer feedback, and finally editing and proofreading prior to submitting the manuscript. Faculty members are encouraged to make writing assignments that students can then convert to publishable manuscripts. Such publications form an essential cornerstone of professional holistic nursing.

  4. Nursing assignment patterns and patient outcomes.

    PubMed

    Sandhu, B; Kerouac, S; Duquette, A; Turchon, S

    1992-01-01

    This article analyzes nursing assignment patterns and patient outcomes critically and comprehensively. Synthesizing empirical data over the past eight years, patient outcomes such as patient satisfaction, and quality of care were examined in association with the main nursing assignment patterns encountered in the literature: case, functional, team, primary and modular. The research results examined do not clearly delineate one assignment pattern or another and it remains illusive, from this analysis, to answer the question most often asked of administrators: "What type of organizational mode would best contribute to the quality of care?" However, this analysis should lead towards decisional impetus for the implementation of new systems of delivery of care, in the present context of limited resources and nursing shortage.

  5. The Airport Gate Assignment Problem: A Survey

    PubMed Central

    Ghaleb, Mageed A.; Salem, Ahmed M.

    2014-01-01

    The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area. PMID:25506074

  6. Medicare Accountable Care Organizations: Beneficiary Assignment Update.

    PubMed

    Vaughn, Thomas; MacKinney, A Clinton; Mueller, Keith J; Ullrich, Fred; Zhu, Xi

    2016-06-01

    This brief updates Brief No. 2014-3 and explains changes in the Centers for Medicare & Medicaid Services (CMS) Accountable Care Organization (ACO) regulations issued in June 2015 pertaining to beneficiary assignment for Medicare Shared Savings Program ACOs. Overall, the regulatory changes are intended to (1) encourage ACOs to participate in two-sided risk contracts, (2) increase the likelihood that beneficiaries are assigned to the physician (and ACO) from whom they receive most of their primary care services, and (3) make it easier for Federally Qualified Health Centers (FQHCs) and Rural Health Clinics (RHCs) to participate in ACOs. Understanding ACO beneficiary assignment policies is critical for ACO in managing their panel of ACO providers and beneficiaries.

  7. Writing Assignments that Promote Active Learning

    NASA Astrophysics Data System (ADS)

    Narayanan, M.

    2014-12-01

    Encourage students to write a detailed, analytical report correlating classroom discussions to an important historical event or a current event. Motivate students interview an expert from industry on a topic that was discussed in class. Ask the students to submit a report with supporting sketches, drawings, circuit diagrams and graphs. Propose that the students generate a complete a set of reading responses pertaining to an assigned topic. Require each student to bring in one comment or one question about an assigned reading. The assignment should be a recent publication in an appropriate journal. Have the students conduct a web search on an assigned topic. Ask them to generate a set of ideas that can relate to classroom discussions. Provide the students with a study guide. The study guide should provide about 10 or 15 short topics. Quiz the students on one or two of the topics. Encourage the students to design or develop some creative real-world examples based on a chapter discussed or a topic of interest. Require that students originate, develop, support and defend a viewpoint using a specifically assigned material. Make the students practice using or utilizing a set of new technical terms they have encountered in an assigned chapter. Have students develop original examples explaining the different terms. Ask the students to select one important terminology from the previous classroom discussions. Encourage the students to explain why they selected that particular word. Ask them to talk about the importance of the terminology from the point of view of their educational objectives and future career. Angelo, T. A. (1991). Ten easy pieces: Assessing higher learning in four dimensions. In T. A. Angelo (Ed.), Classroom research: Early lessons from success (pp. 17-31). New Directions for Teaching and Learning, No. 46. San Francisco: Jossey-Bass.

  8. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Will FDA assign me a registration number? 1271.27 Section 1271.27 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN...

  9. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Will FDA assign me a registration number? 1271.27 Section 1271.27 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN...

  10. 24 CFR 220.252 - Forbearance of foreclosure and assignment of mortgage.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Forbearance of foreclosure and assignment of mortgage. 220.252 Section 220.252 Housing and Urban Development Regulations Relating to...

  11. 24 CFR 220.252 - Forbearance of foreclosure and assignment of mortgage.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Forbearance of foreclosure and assignment of mortgage. 220.252 Section 220.252 Housing and Urban Development Regulations Relating to...

  12. 24 CFR 220.252 - Forbearance of foreclosure and assignment of mortgage.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Forbearance of foreclosure and assignment of mortgage. 220.252 Section 220.252 Housing and Urban Development Regulations Relating to...

  13. 24 CFR 220.252 - Forbearance of foreclosure and assignment of mortgage.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Forbearance of foreclosure and assignment of mortgage. 220.252 Section 220.252 Housing and Urban Development Regulations Relating to...

  14. 24 CFR 220.252 - Forbearance of foreclosure and assignment of mortgage.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Forbearance of foreclosure and assignment of mortgage. 220.252 Section 220.252 Housing and Urban Development Regulations Relating to...

  15. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Will FDA assign me a registration number? 1271.27... (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will...

  16. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Will FDA assign me a registration number? 1271.27... (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will...

  17. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Will FDA assign me a registration number? 1271.27... (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will...

  18. Co-Teachers and Parents' Perceptions of Shortened Assignments for Learning Disabled Students

    ERIC Educational Resources Information Center

    Gutierrez, Yxstian

    2013-01-01

    The Individual with Disabilities in Education Act (IDEA) 2007, a federal special education law, states that students with disabilities requiring special education services can use accommodations or adaptations of the curriculum to access the general education curriculum. A shortened assignment, as an accommodation, can help learning disabled…

  19. OptAssign--A Web-Based Tool for Assigning Students to Groups

    ERIC Educational Resources Information Center

    Meyer, David

    2009-01-01

    A frequent task in educational settings is to assign students to groups based on stated preferences for some projects or topics. This paper introduces a web-based tool supporting both the work flow of collecting student data and the group formation. The latter is based on finding optimal solutions to suitable mathematical assignment problems,…

  20. Context in an Interdisciplinary Algebra Writing Assignment

    ERIC Educational Resources Information Center

    Staats, Susan; Batteen, Chris

    2009-01-01

    Teaching mathematics in real-word contexts is a strategy to make math relevant for undergraduate students. However, very little research exists on students' methods of integrating contextual and mathematical knowledge through writing. This study uses an interdisciplinary writing assignment to investigate the relationship between students' written…

  1. 7 CFR 1430.218 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1430.218 Section 1430.218 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS Milk Income Loss Contract Program §...

  2. Nursing Students Respond to a Computer Assignment.

    ERIC Educational Resources Information Center

    Stamler, Lynnette Leeseberg; Thomas, Barbara; McMahon, Sharon

    1999-01-01

    Nursing students learned to send e-mail, use discussion lists, search the Internet, and critique Web sites while completing an assignment. Evaluation by 44 of 56 students showed they increased their computer literacy; most thought the skills were more relevant to their education than to their future practice. (SK)

  3. On Online Assignments in a Calculus Class

    ERIC Educational Resources Information Center

    Jungic, Veselin; Kent, Deborah; Menz, Petra

    2012-01-01

    In this paper, we describe our experience with the creation and utilization of online assignments for several calculus classes at Simon Fraser University (SFU). We present our findings regarding available software by considering the needs and perspectives of the instructors, students, and administrators. We provide a list of questions that guide…

  4. A Literature Assignment with a Civic Emphasis.

    ERIC Educational Resources Information Center

    Brough, Barbara L.

    1989-01-01

    Describes how students wrestled with an assignment that asked them to name their heroes or heroines, compare them to "Beowulf," and defend their choices in writing and class discussion. Tells how students gained insight into their community and the ways in which people make it better. (MG)

  5. Assigning Publication Credit in Collaborative Research.

    ERIC Educational Resources Information Center

    Bridgwater, Carol Austin; And Others

    Publication credit has taken on great significance with the advent of an increasingly competitive academic job market and the decline in federal funds for psychological research. Policies regarding assignment of publication credit help to mold the careers of academic psychologists. A sample of psychologists was asked to endorse what they…

  6. A Hierarchy of Russian Writing Assignments.

    ERIC Educational Resources Information Center

    Rosengramt, Sandra F.

    1985-01-01

    Examines the implications of the ACTFL Provisional Proficiency Guidelines for the writing curriculum. Argues that the functions identified in the guidelines should be practices in writing as well as in speech. Discusses error correction techniques and presents examples of writing assignments in Russian that elicit advanced-level functions. (SED)

  7. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  8. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  9. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  10. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common...

  11. School Assignment, School Choice and Social Mobility

    ERIC Educational Resources Information Center

    Burgess, Simon; Briggs, Adam

    2010-01-01

    We estimate the chances of poor and non-poor children getting places in good schools, analysing the relationship between poverty, location and school assignment. Our dataset allows us to measure location and distance very precisely. The simple unconditional difference in probabilities of attending a good school is substantial. We run an analysis…

  12. Politics, Internet Assignments, and Civic Knowledge.

    ERIC Educational Resources Information Center

    May, Vaughn

    2000-01-01

    Describes how one professor of American government fights the apathy and cynicism of college students toward politics by using the Internet to help students more fairly appraise the workings of the American political system. One assignment has students research and manage a particular public policy initiative through visits to Web sites…

  13. Assigning Grammatical Gender during Word Production

    ERIC Educational Resources Information Center

    Holmes, Virginia M.; Segui, Juan

    2006-01-01

    The present study was designed to examine the processes by which grammatical gender is assigned during word production. French words varied in strength of sublexical cues, based on whether the word ending was typical for one gender rather than neutral about gender, and lexical cues, derived from the associated definite article being uninformative…

  14. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....25 GHz band must demonstrate that the applicant has exhausted all spectrum available to it in the 12... assigned the band of frequencies from 12.70 to 13.20 GHz. This band is shared with the Fixed-Satellite... narrow band signals. Group D Channels Designation Channel boundaries (GHz) Alternate channel...

  15. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....25 GHz band must demonstrate that the applicant has exhausted all spectrum available to it in the 12... assigned the band of frequencies from 12.70 to 13.20 GHz. This band is shared with the Fixed-Satellite... narrow band signals. Group D Channels Designation Channel boundaries (GHz) Alternate channel...

  16. A Photographic Assignment for Abstract Algebra

    ERIC Educational Resources Information Center

    Warrington, Gregory S.

    2009-01-01

    We describe a simple photographic assignment appropriate for an abstract algebra (or other) course. Students take digital pictures around campus of various examples of symmetry. They then classify these pictures according to which of the 17 plane symmetry groups they belong. (Contains 2 figures.)

  17. Democratization of Learning through Thematic Assignment

    ERIC Educational Resources Information Center

    Medellu, Christophil S.; Lumingkewas, S.; Walangitan, J. F.

    2015-01-01

    This article describes the results of research on learning democratization in Sangihe. This study is the first year of a five-year plan. Long-term goal of this research is to create the democratic science learning in schools. Democratic learning model was developed through thematic assignment, involving the participation of parents and…

  18. 20 CFR 61.404 - Assignments; creditors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Assignments; creditors. 61.404 Section 61.404 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY, DISABILITY, DEATH, OR ENEMY DETENTION OF EMPLOYEES OF CONTRACTORS WITH THE UNITED STATES CLAIMS...

  19. Teaching Historical Analysis through Creative Writing Assignments

    ERIC Educational Resources Information Center

    Peterson, Janine Larmon; Graham, Lea

    2015-01-01

    Incorporating creative writing exercises in history courses can heighten students' critical reading and analytical skills in an active learning model. We identify and define two types of possible assignments that use model texts as their locus: centripetal, which focuses on specific context and disciplinary terms, and centrifugal, which address…

  20. Payload flight assignments: NASA mixed fleet

    NASA Technical Reports Server (NTRS)

    Starkey, Norman

    1993-01-01

    This mixed fleet manifest, which serves as the baseline for planning purposes, includes payload flight assignments for the Space Shuttle through FY 1995 and NASA expendable launch vehicle (EVL) missions through FY 1999. The FY 1996-1999 Shuttle manifest planning is omitted pending Space Station redesign. Also included in this document are a list of previous flights, payload requests, and payload/acronyms.

  1. Writing Assignments Based on Literary Works.

    ERIC Educational Resources Information Center

    Matthews, Dorothy, Ed.

    1985-01-01

    The literature selections serving as the basis for writing assignments in the articles in this journal issue range from time-honored English classics ("Beowulf,""Sir Gawain and the Green Knight") and American standards ("A Farewell to Arms,""The Scarlet Letter") to contemporary fiction. The articles deal with works by women writers (Shirley…

  2. 44 CFR 295.14 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Assignments. 295.14 Section 295.14 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Bringing a Claim Under the CGFAA §...

  3. 44 CFR 295.14 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Assignments. 295.14 Section 295.14 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Bringing a Claim Under the CGFAA §...

  4. Generalised Assignment Matrix Methodology in Linear Programming

    ERIC Educational Resources Information Center

    Jerome, Lawrence

    2012-01-01

    Discrete Mathematics instructors and students have long been struggling with various labelling and scanning algorithms for solving many important problems. This paper shows how to solve a wide variety of Discrete Mathematics and OR problems using assignment matrices and linear programming, specifically using Excel Solvers although the same…

  5. 7 CFR 1430.218 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Assignments. 1430.218 Section 1430.218 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS Milk Income Loss Contract Program §...

  6. 7 CFR 1430.218 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Assignments. 1430.218 Section 1430.218 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS Milk Income Loss Contract Program §...

  7. Repeatable Writing Assignments to Enhance Student Writing.

    ERIC Educational Resources Information Center

    Wiebold, W. J.; And Others

    1990-01-01

    Discussed is the use of two short writing assignments and a peer review system in an undergraduate agronomy course to improve writing skills and the learning of agronomic principles. Provided is a course description and procedures used in the course. Student evaluation in the course is reviewed. (CW)

  8. Assignment Of Finite Elements To Parallel Processors

    NASA Technical Reports Server (NTRS)

    Salama, Moktar A.; Flower, Jon W.; Otto, Steve W.

    1990-01-01

    Elements assigned approximately optimally to subdomains. Mapping algorithm based on simulated-annealing concept used to minimize approximate time required to perform finite-element computation on hypercube computer or other network of parallel data processors. Mapping algorithm needed when shape of domain complicated or otherwise not obvious what allocation of elements to subdomains minimizes cost of computation.

  9. 33 CFR 20.201 - Assignment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Assignment. 20.201 Section 20.201 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL RULES OF PRACTICE, PROCEDURE, AND EVIDENCE FOR FORMAL ADMINISTRATIVE PROCEEDINGS OF THE COAST GUARD Administrative Law...

  10. Assigning cause for sudden unexpected infant death.

    PubMed

    Hunt, Carl E; Darnall, Robert A; McEntire, Betty L; Hyma, Bruce A

    2015-06-01

    We have reached a conundrum in assigning cause of death for sudden unexpected infant deaths. We summarize the discordant perspectives and approaches and how they have occurred, and recommend a pathway toward improved consistency. This lack of consistency affects pediatricians and other health care professionals, scientific investigators, medical examiners and coroners, law enforcement agencies, families, and support or advocacy groups. We recommend that an interdisciplinary international committee be organized to review current approaches for assigning cause of death, and to identify a consensus strategy for improving consistency. This effort will need to encompass intrinsic risk factors or infant vulnerability in addition to known environmental risk factors including unsafe sleep settings, and must be sufficiently flexible to accommodate a progressively expanding knowledge base. PMID:25634430

  11. Optimum frequency assignment for satellite SCPC systems

    NASA Astrophysics Data System (ADS)

    Okinaka, H.; Yasuda, Y.; Hirata, Y.

    A technique for deriving a quasi-optimum solution for IM-minimum channel allocation for single-level SCPC systems is presented. Two types of IM products are considered as the dominant components in an RF band. The third order IM product is proportional to the product of the power of concerned carriers, allowing a weighting function to be defined for calculating the IM noise. An IM minimum channel allocation technique can then be used to reduce the IM noise occurring in the carrier slots through frequency assignment. The worst carrier is automatically deleted with an initial channel allocation and the process is iterated until the maximum noise reduction is obtained. The first two or three carriers are assigned to unused frequency slots with low noise. The method is also viable when dealing with a larger number of carriers.

  12. 38 CFR 19.3 - Assignment of proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Assignment of proceedings... Assignment of proceedings. (a) Assignment. The Chairman may assign a proceeding instituted before the Board, including any motion, to an individual Member or to a panel of three or more Members for adjudication...

  13. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Work assignments. 1552.211... Work assignments. As prescribed in 1511.011-74, insert the following contract clause in cost-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a)...

  14. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Work assignments. 1552.211... Work assignments. As prescribed in 1511.011-74, insert the following contract clause in cost-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a)...

  15. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Work assignments. 1552.211... Work assignments. As prescribed in 1511.011-74, insert the following contract clause in cost-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a)...

  16. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Work assignments. 1552.211... Work assignments. As prescribed in 1511.011-74, insert the following contract clause in cost-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a)...

  17. 12 CFR 228.28 - Assigned ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... In connection with any type of lending activity described in § 228.22(a), evidence of discriminatory... 8 of the Real Estate Settlement Procedures Act; and (v) Violations of the Truth in Lending...

  18. Replicating and Extending Research on the Partial Assignment Completion Effect: Is Sunk Cost Related to Partial Assignment Completion Strength?

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Taylor, Emily P.; Skinner, Christopher H.; Parkhurst, John; Nalls, Meagan L.

    2014-01-01

    After students acquire a skill, mastery often requires them to choose to engage in assigned academic activities (e.g., independent seatwork, and homework). Although students may be more likely to choose to work on partially completed assignments than on new assignments, the partial assignment completion (PAC) effect may not be very powerful. The…

  19. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PUBLIC DEBT GENERAL REGULATIONS GOVERNING U.S. SECURITIES Assignments by or in Behalf of Individuals § 306.56 Assignment of securities registered in the names of or assigned to two or more persons. (a... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Assignment of securities...

  20. Act resilient.

    PubMed

    Joseph, Genie; Bice-Stephens, Wynona

    2014-01-01

    Attendees have reported changing from being fearful to serene, from listless to energized, from disengaged to connected, and becoming markedly less anxious in a few weeks. Anecdotally, self-reported stress levels have been reduced by over 50% after just one class. Attendees learn not to be afraid of their feelings by working with emotions in a playful manner. When a person can act angry, but separate himself from his personal story, the emotional energy exists in a separate form that is not attached to specific events, and can be more easily dealt with and neutralized. Attendees are taught to "take out the emotional trash" through expressive comedy. They become less intimated by their own emotional intensity and triggers as they learn how even metaphorical buckets of anger, shame, guilt and hurt can be emotionally emptied. The added benefit is that this is accomplished without the disclosure of personal information of the requirement to reexperience past pain which can trigger its own cascade of stress. PMID:24706248

  1. Assigned value improves memory of proper names.

    PubMed

    Festini, Sara B; Hartley, Alan A; Tauber, Sarah K; Rhodes, Matthew G

    2013-01-01

    Names are more difficult to remember than other personal information such as occupations. The current research examined the influence of assigned point value on memory and metamemory judgements for names and occupations to determine whether incentive can improve recall of proper names. In Experiment 1 participants studied face-name and face-occupation pairs assigned 1 or 10 points, made judgements of learning, and were given a cued recall test. High-value names were recalled more often than low-value names. However, recall of occupations was not influenced by value. In Experiment 2 meaningless nonwords were used for both names and occupations. The name difficulty disappeared, and value influenced recall of both names and occupations. Thus value similarly influenced names and occupations when meaningfulness was held constant. In Experiment 3 participants were required to use overt rote rehearsal for all items. Value did not boost recall of high-value names, suggesting that differential processing could not be implemented to improve memory. Thus incentives may improve memory for proper names by motivating people to engage in selective rehearsal and effortful elaborative processing.

  2. Assigning functional meaning to digital circuits

    SciTech Connect

    Eckmann, S.T.; Chisholm, G.H.

    1997-07-01

    During computer-aided design, the problem of how to determine the logical function of a digital circuit arises in many contexts. For example, assigning functional meaning to a circuit is a fundamental operation in both reverse engineering and implementation validation. This report describes such a determination by discussing how a higher-level functional representation is constructed from a detailed circuit description (i.e., a gate-level netlist, which is a list of logic gates and their interconnections). The approach used involves transforming parts of the netlist into a functional representation and then manipulating this representation. Two types of functional representations are described: (1) a mathematical representation based on the logical operators ``exor`` and ``and`` and (2) a directed acyclic graph representation based on binary decision trees. Each representation provides a canonical form of the logical function being implemented (i.e., a form that is independent of implementation details). Such forms, however, have a well-known problem associated with the ordering of inputs: for each order, a unique form exists. A solution to this problem is given for both representations. Experimental results that demonstrate the use of these representations in the process of assigning functional meaning to a circuit are provided. The report also identifies and discusses issues critical to the performance required of this fundamental operation.

  3. Approximate algorithms for partitioning and assignment problems

    NASA Technical Reports Server (NTRS)

    Iqbal, M. A.

    1986-01-01

    The problem of optimally assigning the modules of a parallel/pipelined program over the processors of a multiple computer system under certain restrictions on the interconnection structure of the program as well as the multiple computer system was considered. For a variety of such programs it is possible to find linear time if a partition of the program exists in which the load on any processor is within a certain bound. This method, when combined with a binary search over a finite range, provides an approximate solution to the partitioning problem. The specific problems considered were: a chain structured parallel program over a chain-like computer system, multiple chain-like programs over a host-satellite system, and a tree structured parallel program over a host-satellite system. For a problem with m modules and n processors, the complexity of the algorithm is no worse than O(mnlog(W sub T/epsilon)), where W sub T is the cost of assigning all modules to one processor and epsilon the desired accuracy.

  4. Pay Equity Act, 19 May 1989.

    PubMed

    1989-01-01

    This document contains major provisions of the 1989 Pay Equity Act of the Province of New Brunswick, Canada. This Act implements pay equity to public service employees. The Act sets out the conditions which may prevail and cause differences in pay between a female-dominated class and a male-dominated class. These include a formal seniority system which does not discriminate on the basis of gender, a temporary employee training assignment, a merit pay plan that does not discriminate, a gender-neutral reevaluation process to down-grade a position, or a temporary increase in pay due to a skills shortage. The Act provides that comparisons be made between female-dominated classes and male-dominated classes in terms of pay on an hourly basis and the value of the work performed. No employee is to have pay reduced in order to implement this Act.

  5. Development, social norms, and assignment to task

    PubMed Central

    Fafchamps, Marcel

    2011-01-01

    Economic development involves a structural transformation in the way people are allocated to tasks. There is a shift from self-provision to market exchange, facilitating specialization. There is also a shift from self-employment to wage employment in large firms and organizations, driven by innovation and increasing returns to scale. Changes in allocation mechanisms require changes in norms and attitudes. Because different labor assignment domains coexist, conflicts arise among norms that apply to different domains, possibly resulting in dysfunctional outcomes. I argue that religion, humanism, and schools have all played an important historical role in fostering the changes in social norms and attitudes that are needed to accompany structural changes in the way economies allocate workers to tasks. PMID:22198757

  6. Y(4260) and possible charmonium assignment

    SciTech Connect

    Llanes-Estrada, Felipe J.

    2005-08-01

    The newly reported Y(4260) becomes the second most massive state in the charmonium family. We argue that it displaces the {psi}(4415) as the (largely) 4s vector charmonium state, recall s-d wave interference to explain the lack of a signal in e{sup -}e{sup +}{yields}hadrons and suggest some further study avenues that can exclude exotic meson assignments. The absence of a J/{psi}KK mode can be understood, beyond phase space suppression, to be a consequence of chiral symmetry. We also provide a model calculation in this sector showing that, although forcing the fit somewhat (which suggests a small sea quark wave function component), the state can be incorporated in a standard scheme.

  7. A multistage linear array assignment problem

    NASA Technical Reports Server (NTRS)

    Nicol, David M.; Shier, D. R.; Kincaid, R. K.; Richards, D. S.

    1988-01-01

    The implementation of certain algorithms on parallel processing computing architectures can involve partitioning contiguous elements into a fixed number of groups, each of which is to be handled by a single processor. It is desired to find an assignment of elements to processors that minimizes the sum of the maximum workloads experienced at each stage. This problem can be viewed as a multi-objective network optimization problem. Polynomially-bounded algorithms are developed for the case of two stages, whereas the associated decision problem (for an arbitrary number of stages) is shown to be NP-complete. Heuristic procedures are therefore proposed and analyzed for the general problem. Computational experience with one of the exact problems, incorporating certain pruning rules, is presented with one of the exact problems. Empirical results also demonstrate that one of the heuristic procedures is especially effective in practice.

  8. Rationalization of some genetic anticodonic assignments

    NASA Technical Reports Server (NTRS)

    Lacey, J. C., Jr.; Hall, L. M.; Mullins, D. W., Jr.

    1985-01-01

    The hydrophobicity of most amino acids correlates well with that of their anticodon nucleotides, with Trp, Tyr, Ile, and Ser being the exceptions to this rule. Using previous data on hydrophobicity and binding constants, and new data on rates of esterification of polyadenylic acid with several N-acetylaminoacyl imidazolides, several of the anticodon assignments are rationalized. Chemical reasons are shown supporting the idea of the inclusion of the Ile in the catalog of biological amino acids late in the evolution, through a mutation of the existing tRNA and its aminoacyl-tRNA-synthetase. It was found that an addition of hexane increases the incorporation of hydrophobic Ac-Phe into poly-A, in support of the Fox (1965) and Oparin (1965) emphasis on the biogenetic importance of phase-separated systems.

  9. 27 CFR 17.4 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false OMB control numbers... ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DRAWBACK ON TAXPAID DISTILLED SPIRITS USED IN MANUFACTURING NONBEVERAGE PRODUCTS General Provisions § 17.4 OMB control numbers...

  10. 16 CFR 1.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...(all numbers begin with 3084-) 16 CFR part where the information collection requirement is located (or.... 0025 453. 0068 306. 0069 305. 0085 12 CFR part 205; 12 CFR part 1005. 0086 12 CFR part 213; 12 CFR part 1013. 0087 12 CFR part 202; 12 CFR part 1002. 0088 12 CFR part 226; 12 CFR part 1026. 0094 309....

  11. 7 CFR 35.60 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Withholding Certificates § 35.60...

  12. 7 CFR 33.60 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE...

  13. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false OMB control numbers... Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES OMB CONTROL...

  14. 7 CFR 1404.9 - OMB Control Numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES... information collection requirements contained in this part have been approved by the Office of Management...

  15. 3 CFR - Assignment of Reporting Functions Under the Supplemental Appropriations Act, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Secretary of State the Secretary of Defense the Attorney General the Director of National Intelligence By the authority vested in me as President by the Constitution and the laws of the United States, including section 301 of title 3, United States Code, I......

  16. 75 FR 69126 - Proposed Information Collection Request (ICR) for the Workforce Investment Act Random Assignment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Security Administration, Temporary Assistance for Needy Families Program, and/or the Supplemental Nutrition... attainment of education credentials, labor market outcomes, and family self- sufficiency. 3. WIA Service...

  17. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... requirement. (b) Display. CFR part or section where the information collection requirement is located Current OMB control number (all numbers begin with 0648-) 15 CFR Part 908 -0025 Part 911 -0157 917.11 -0008....9 -0141 Part 960, subpart B -0174 Part 970 -0145 Part 971 -0170 Part 981 -0144 50 CFR 216.22...

  18. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... requirement. (b) Display. CFR part or section where the information collection requirement is located Current OMB control number (all numbers begin with 0648-) 15 CFR Part 908 -0025 Part 911 -0157 917.11 -0008....9 -0141 Part 960, subpart B -0174 Part 970 -0145 Part 971 -0170 Part 981 -0144 50 CFR 216.22...

  19. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... requirement. (b) Display. CFR part or section where the information collection requirement is located Current OMB control number (all numbers begin with 0648-) 15 CFR Part 908 -0025 Part 911 -0157 917.11 -0008....9 -0141 Part 960, subpart B -0174 Part 970 -0145 Part 971 -0170 Part 981 -0144 50 CFR 216.22...

  20. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... requirement. (b) Display. CFR part or section where the information collection requirement is located Current OMB control number (all numbers begin with 0648-) 15 CFR Part 908 -0025 Part 911 -0157 917.11 -0008....9 -0141 Part 960, subpart B -0174 Part 970 -0145 Part 971 -0170 Part 981 -0144 50 CFR 216.22...

  1. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... requirement. (b) Display. CFR part or section where the information collection requirement is located Current OMB control number (all numbers begin with 0648-) 15 CFR Part 908 -0025 Part 911 -0157 917.11 -0008....9 -0141 Part 960, subpart B -0174 Part 970 -0145 Part 971 -0170 Part 981 -0144 50 CFR 216.22...

  2. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... Form U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  3. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... Form U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  4. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  5. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... Form U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  6. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  7. 7 CFR 1207.534 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF... part have been approved by the Office of Management and Budget (OMB) under the provisions of 44...

  8. 7 CFR 46.47 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF... by the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and...

  9. 7 CFR 1230.120 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF... recordkeeping requirements contained in this part have been approved by the Office of Management and Budget...

  10. 7 CFR 35.60 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY... contained in this part have been approved by the Office of Management and Budget (OMB) under the...

  11. 7 CFR 46.47 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF... by the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and...

  12. 7 CFR 46.47 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF... by the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and...

  13. 7 CFR 1207.534 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF... part have been approved by the Office of Management and Budget (OMB) under the provisions of 44...

  14. 7 CFR 46.47 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF... by the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and...

  15. 7 CFR 46.47 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF... by the Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and...

  16. 77 FR 5850 - Notice of Random Assignment Study To Evaluate Workforce Investment Act Adult and Dislocated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ... evaluation study period. On July 21, 2011 (76 FR 43729-43731), the Department solicited comments concerning... commenter correctly points out, the activities labeled as core, intensive, and training vary by LWIA... customers are trained. However, a study of the impacts of training in Europe finds that the magnitude of...

  17. Solving multiconstraint assignment problems using learning automata.

    PubMed

    Horn, Geir; Oommen, B John

    2010-02-01

    This paper considers the NP-hard problem of object assignment with respect to multiple constraints: assigning a set of elements (or objects) into mutually exclusive classes (or groups), where the elements which are "similar" to each other are hopefully located in the same class. The literature reports solutions in which the similarity constraint consists of a single index that is inappropriate for the type of multiconstraint problems considered here and where the constraints could simultaneously be contradictory. This feature, where we permit possibly contradictory constraints, distinguishes this paper from the state of the art. Indeed, we are aware of no learning automata (or other heuristic) solutions which solve this problem in its most general setting. Such a scenario is illustrated with the static mapping problem, which consists of distributing the processes of a parallel application onto a set of computing nodes. This is a classical and yet very important problem within the areas of parallel computing, grid computing, and cloud computing. We have developed four learning-automata (LA)-based algorithms to solve this problem: First, a fixed-structure stochastic automata algorithm is presented, where the processes try to form pairs to go onto the same node. This algorithm solves the problem, although it requires some centralized coordination. As it is desirable to avoid centralized control, we subsequently present three different variable-structure stochastic automata (VSSA) algorithms, which have superior partitioning properties in certain settings, although they forfeit some of the scalability features of the fixed-structure algorithm. All three VSSA algorithms model the processes as automata having first the hosting nodes as possible actions; second, the processes as possible actions; and, third, attempting to estimate the process communication digraph prior to probabilistically mapping the processes. This paper, which, we believe, comprehensively reports the

  18. Improving load balance with flexibly assignable tasks

    SciTech Connect

    Pinar, Ali; Hendrickson, Bruce

    2003-09-09

    In many applications of parallel computing, distribution ofthe data unambiguously implies distribution of work among processors. Butthere are exceptions where some tasks can be assigned to one of severalprocessors without altering the total volume of communication. In thispaper, we study the problem of exploiting this flexibility in assignmentof tasks to improve load balance. We first model the problem in terms ofnetwork flow and use combinatorial techniques for its solution. Ourparametric search algorithms use maximum flow algorithms for probing on acandidate optimal solution value. We describe two algorithms to solve theassignment problem with \\logW_T and vbar P vbar probe calls, w here W_Tand vbar P vbar, respectively, denote the total workload and number ofproce ssors. We also define augmenting paths and cuts for this problem,and show that anyalgorithm based on augmenting paths can be used to findan optimal solution for the task assignment problem. We then consideracontinuous version of the problem, and formulate it as a linearlyconstrained optimization problem, i.e., \\min\\|Ax\\|_\\infty,\\; {\\rms.t.}\\;Bx=d. To avoid solving an intractable \\infty-norm optimization problem,we show that in this case minimizing the 2-norm is sufficient to minimizethe \\infty-norm, which reduces the problem to the well-studiedlinearly-constrained least squares problem. The continuous version of theproblem has the advantage of being easily amenable to parallelization.Our experiments with molecular dynamics and overlapped domaindecomposition applications proved the effectiveness of our methods withsignificant improvements in load balance. We also discuss how ourtechniques can be enhanced for heterogeneous systems.

  19. Assigning Priorities for Fixed Priority Preemption Threshold Scheduling

    PubMed Central

    2015-01-01

    Preemption threshold scheduling (PTS) enhances real-time schedulability by controlling preemptiveness of tasks. This benefit of PTS highly depends on a proper algorithm that assigns each task feasible scheduling attributes, which are priority and preemption threshold. Due to the existence of an efficient optimal preemption threshold assignment algorithm that works with fully assigned priority orderings, we need an optimal priority assignment algorithm for PTS. This paper analyzes the inefficiency or nonoptimality of the previously proposed optimal priority assignment algorithms for PTS. We develop theorems for exhaustively but safely pruning infeasible priority orderings while assigning priorities to tasks for PTS. Based on the developed theorems, we correct the previously proposed optimal priority assignment algorithm for PTS. We also propose a performance improved optimal priority assignment algorithm for PTS proving its optimality. The empirical evaluation results clearly show the effectiveness of the proposed algorithm. PMID:26688828

  20. A Linear Programming Model for Assigning Students to Attendance Centers.

    ERIC Educational Resources Information Center

    Ontjes, Robert L.

    A linear programing model and procedures for optimal assignment of students to attendance centers are presented. An example of the use of linear programing for the assignment of students to attendance centers in a particular school district is given. (CK)

  1. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television...

  2. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television...

  3. 7 CFR 1404.3 - Payments which may be assigned.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF AGRICULTURE GENERAL REGULATIONS AND POLICIES ASSIGNMENT OF PAYMENTS § 1404.3 Payments which may be assigned. Except as otherwise provided in this part or in individual program regulations, contracts...

  4. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television...

  5. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television...

  6. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television...

  7. Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course.

    PubMed

    Mynlieff, Michelle; Manogaran, Anita L; St Maurice, Martin; Eddinger, Thomas J

    2014-01-01

    Writing assignments, including note taking and written recall, should enhance retention of knowledge, whereas analytical writing tasks with metacognitive aspects should enhance higher-order thinking. In this study, we assessed how certain writing-intensive "interventions," such as written exam corrections and peer-reviewed writing assignments using Calibrated Peer Review and including a metacognitive component, improve student learning. We designed and tested the possible benefits of these approaches using control and experimental variables across and between our three-section introductory biology course. Based on assessment, students who corrected exam questions showed significant improvement on postexam assessment compared with their nonparticipating peers. Differences were also observed between students participating in written and discussion-based exercises. Students with low ACT scores benefited equally from written and discussion-based exam corrections, whereas students with midrange to high ACT scores benefited more from written than discussion-based exam corrections. Students scored higher on topics learned via peer-reviewed writing assignments relative to learning in an active classroom discussion or traditional lecture. However, students with low ACT scores (17-23) did not show the same benefit from peer-reviewed written essays as the other students. These changes offer significant student learning benefits with minimal additional effort by the instructors.

  8. Understanding Test-Type Assignment: Why Do Special Educators Make Unexpected Test-Type Assignments?

    ERIC Educational Resources Information Center

    Cho, Hyun-Jeong; Kingston, Neal

    2014-01-01

    We interviewed special educators (a) whose students with disabilities (SWDs) were proficient on the 2008 general education assessment but were assigned to the 2009 alternate assessment based on modified achievement standards (AA-MAS), and (b) whose students with mild disabilities took the 2008 alternate assessment based on alternate achievement…

  9. Assignment Choice: Do Students Choose Briefer Assignments or Finishing What They Started?

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Skinner, Christopher H.; Parkhurst, John; O'Neil, Michael; Conley, Elisha

    2010-01-01

    Academic skill development requires engagement in effortful academic behaviors. Although students may be more likely to choose to engage in behaviors that require less effort, they also may be motivated to complete assignments that they have already begun. Seventh-grade students (N = 88) began a mathematics computation worksheet, but were stopped…

  10. A practical guide to making patient assignments in acute care.

    PubMed

    Cathro, Heather

    2013-01-01

    Charge nurses have integral roles in healthcare organizations. Making patient assignments is an important charge nurse role that lacks theoretical support and practical guidelines. Based on a concept analysis of the charge nurse role, the author looks at a theory-gap analysis regarding how patient assignments are made and proposes a framework to guide the process of patient assignments. PMID:23232175

  11. 46 CFR 42.09-1 - Assignment of load lines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Assignment of load lines. 42.09-1 Section 42.09-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Load Line Assignments and Surveys-General Requirements § 42.09-1 Assignment of load lines....

  12. 29 CFR 2700.50 - Assignment of Judges.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Assignment of Judges. 2700.50 Section 2700.50 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.50 Assignment of Judges. Judges shall be assigned cases in rotation as far as practicable....

  13. 29 CFR 2700.50 - Assignment of Judges.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Assignment of Judges. 2700.50 Section 2700.50 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.50 Assignment of Judges. Judges shall be assigned cases in rotation as far as practicable....

  14. 29 CFR 2700.50 - Assignment of Judges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Assignment of Judges. 2700.50 Section 2700.50 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.50 Assignment of Judges. Judges shall be assigned cases in rotation as far as practicable....

  15. 29 CFR 2700.50 - Assignment of Judges.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Assignment of Judges. 2700.50 Section 2700.50 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.50 Assignment of Judges. Judges shall be assigned cases in rotation as far as practicable....

  16. 29 CFR 2700.50 - Assignment of Judges.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Assignment of Judges. 2700.50 Section 2700.50 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.50 Assignment of Judges. Judges shall be assigned cases in rotation as far as practicable....

  17. 34 CFR 682.508 - Assignment of a loan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Federal Guaranteed Student Loan Programs § 682.508 Assignment of a loan. (a) General. A Federal GSL loan may not be assigned... 34 Education 4 2011-07-01 2011-07-01 false Assignment of a loan. 682.508 Section 682.508...

  18. 34 CFR 682.508 - Assignment of a loan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Federal Guaranteed Student Loan Programs § 682.508 Assignment of a loan. (a) General. A Federal GSL loan may not be assigned... 34 Education 4 2013-07-01 2013-07-01 false Assignment of a loan. 682.508 Section 682.508...

  19. 34 CFR 682.508 - Assignment of a loan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Federal Guaranteed Student Loan Programs § 682.508 Assignment of a loan. (a) General. A Federal GSL loan may not be assigned... 34 Education 4 2012-07-01 2012-07-01 false Assignment of a loan. 682.508 Section 682.508...

  20. 34 CFR 682.508 - Assignment of a loan.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Federal Guaranteed Student Loan Programs § 682.508 Assignment of a loan. (a) General. A Federal GSL loan may not be assigned except to another... 34 Education 3 2010-07-01 2010-07-01 false Assignment of a loan. 682.508 Section 682.508...

  1. Assessment of a Diversity Assignment in a PR Principles Course

    ERIC Educational Resources Information Center

    Gallicano, Tiffany Derville; Stansberry, Kathleen

    2012-01-01

    This study assesses an assignment for incorporating diversity into the principles of public relations course. The assignment is tailored to the challenges of using an active learning approach in a large lecture class. For the assignment, students write a goal, objectives, strategies, an identification of tactics, and evaluation plans for either…

  2. 4 CFR 3.1 - Appointment, promotion, and assignment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Appointment, promotion, and assignment. 3.1 Section 3.1 Accounts GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL SYSTEM EMPLOYMENT § 3.1 Appointment, promotion, and assignment. Employees of GAO shall be appointed, promoted and assigned solely on the basis of merit...

  3. Social Studies Textbooks and the Teaching of Assigned Writing.

    ERIC Educational Resources Information Center

    Donlan, Dan

    This paper initially presents the results of several studies concerning the kind of writing assigned by social studies teachers and the kind of writing assigned by social studies textbooks. The second part of this paper describes several things social studies teachers using textbook writing assignments might do to clarify for students what is…

  4. 42 CFR 405.912 - Assignment of appeal rights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Assignment of appeal rights. 405.912 Section 405..., Reconsiderations, and Appeals Under Original Medicare (Part A and Part B) § 405.912 Assignment of appeal rights. (a... assignment of appeal rights from the beneficiary for that item or service. (b) Who may not be an assignee....

  5. 5 CFR 870.1207 - Designations, assignments, and court orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Option B, that assignment remains in effect. (2) If an individual with ported coverage wishes to make an assignment, he/she must submit the form to the Portability Office. (3) If an individual with ported coverage... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Designations, assignments, and...

  6. Science Textbooks and the Teaching of Assigned Writing.

    ERIC Educational Resources Information Center

    Donlan, Dan

    This paper initially presents the results of several studies concerning what kind of writing science teachers assign and what kind of writing science textbooks assign. By far, reporting was the most popular type of writing assigned in the surveyed textbooks, although other types of writing were in evidence. Exposition tended to take three forms:…

  7. Mathematics Textbooks and the Teaching of Assigned Writing.

    ERIC Educational Resources Information Center

    Donlan, Dan

    This paper initially presents the results of several studies concerning what kind of writing mathematics teachers assign and what kind of writing mathematics textbooks assign. By far, report-research was the most popular type of writing assigned in the surveyed textbooks. The types of reports students were asked to write include biography,…

  8. 7 CFR 762.160 - Assignment of guarantee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of the loan. The holder must assign the guaranteed portion back to the original lender if requested... AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.160 Assignment of guarantee. (a) The following general requirements apply to assigning guaranteed loans: (1) Subject to Agency concurrence, the...

  9. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement....

  10. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement....

  11. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement....

  12. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement....

  13. 48 CFR 1511.011-74 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Work assignments. 1511.011... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS 1511.011-74 Work assignments. The Contracting Officer shall insert the contract clause at 1552.211-74, Work Assignments, in cost-reimbursement type term...

  14. Learning through Writing: Teaching Critical Thinking Skills in Writing Assignments

    ERIC Educational Resources Information Center

    Cavdar, Gamze; Doe, Sue

    2012-01-01

    Traditional writing assignments often fall short in addressing problems in college students' writing as too often these assignments fail to help students develop critical thinking skills and comprehension of course content. This article reports the use of a two-part (staged) writing assignment with postscript as a strategy for improving critical…

  15. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... literacy program by § 544.71. (a) Appointment. (1) An inmate who does not meet the literacy requirement may be assigned to a grade 4 position contingent upon the inmate's continued enrollment in the...

  16. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... literacy program by § 544.71. (a) Appointment. (1) An inmate who does not meet the literacy requirement may be assigned to a grade 4 position contingent upon the inmate's continued enrollment in the...

  17. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... literacy program by § 544.71. (a) Appointment. (1) An inmate who does not meet the literacy requirement may be assigned to a grade 4 position contingent upon the inmate's continued enrollment in the...

  18. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... literacy program by § 544.71. (a) Appointment. (1) An inmate who does not meet the literacy requirement may be assigned to a grade 4 position contingent upon the inmate's continued enrollment in the...

  19. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... literacy program by § 544.71. (a) Appointment. (1) An inmate who does not meet the literacy requirement may be assigned to a grade 4 position contingent upon the inmate's continued enrollment in the...

  20. A new algorithm for reliable and general NMR resonance assignment.

    PubMed

    Schmidt, Elena; Güntert, Peter

    2012-08-01

    The new FLYA automated resonance assignment algorithm determines NMR chemical shift assignments on the basis of peak lists from any combination of multidimensional through-bond or through-space NMR experiments for proteins. Backbone and side-chain assignments can be determined. All experimental data are used simultaneously, thereby exploiting optimally the redundancy present in the input peak lists and circumventing potential pitfalls of assignment strategies in which results obtained in a given step remain fixed input data for subsequent steps. Instead of prescribing a specific assignment strategy, the FLYA resonance assignment algorithm requires only experimental peak lists and the primary structure of the protein, from which the peaks expected in a given spectrum can be generated by applying a set of rules, defined in a straightforward way by specifying through-bond or through-space magnetization transfer pathways. The algorithm determines the resonance assignment by finding an optimal mapping between the set of expected peaks that are assigned by definition but have unknown positions and the set of measured peaks in the input peak lists that are initially unassigned but have a known position in the spectrum. Using peak lists obtained by purely automated peak picking from the experimental spectra of three proteins, FLYA assigned correctly 96-99% of the backbone and 90-91% of all resonances that could be assigned manually. Systematic studies quantified the impact of various factors on the assignment accuracy, namely the extent of missing real peaks and the amount of additional artifact peaks in the input peak lists, as well as the accuracy of the peak positions. Comparing the resonance assignments from FLYA with those obtained from two other existing algorithms showed that using identical experimental input data these other algorithms yielded significantly (40-142%) more erroneous assignments than FLYA. The FLYA resonance assignment algorithm thus has the

  1. A Bayesian approach to simultaneously quantify assignments and linguistic uncertainty

    SciTech Connect

    Chavez, Gregory M; Booker, Jane M; Ross, Timothy J

    2010-10-07

    Subject matter expert assessments can include both assignment and linguistic uncertainty. This paper examines assessments containing linguistic uncertainty associated with a qualitative description of a specific state of interest and the assignment uncertainty associated with assigning a qualitative value to that state. A Bayesian approach is examined to simultaneously quantify both assignment and linguistic uncertainty in the posterior probability. The approach is applied to a simplified damage assessment model involving both assignment and linguistic uncertainty. The utility of the approach and the conditions under which the approach is feasible are examined and identified.

  2. Integrating environmental isoscapes for spatiotemporal assignment

    NASA Astrophysics Data System (ADS)

    Bowen, G.; Bataille, C.; Kennedy, C.; Zhang, T.; West, J.

    2012-04-01

    Numerous case studies in the ecological and forensic fields have illustrated the potential utility of light stable isotopes as tracers of the geographic origin of biological materials. However, a number of critical challenges continue to limit the application of these tools, among them (1) limitations to our knowledge of isotopic values expected for materials formed at particular locations and times, (2) uncertainty in our understanding of the interplay between temporal and spatial variation in the isotope 'signature' transferred to isotopic materials, and (3) lack of robust, widely used models for quantitative statistical assessment of spatiotemporal origin and associated uncertainty. In order to acknowledge and address each of these limitations, we present new models and analysis of spatiotemporal variation in the stable isotope ratios of hydrogen, oxygen, and strontium in the environment, representing three isotope systems with strong and complementary potential for provenancing applications. We demonstrate a statistical framework for the integration of these isoscapes in assignment problems and describe how this toolkit has been made broadly accessible through the IsoMAP web-GIS portal.

  3. Efficient Credit Assignment through Evaluation Function Decomposition

    NASA Technical Reports Server (NTRS)

    Agogino, Adrian; Turner, Kagan; Mikkulainen, Risto

    2005-01-01

    Evolutionary methods are powerful tools in discovering solutions for difficult continuous tasks. When such a solution is encoded over multiple genes, a genetic algorithm faces the difficult credit assignment problem of evaluating how a single gene in a chromosome contributes to the full solution. Typically a single evaluation function is used for the entire chromosome, implicitly giving each gene in the chromosome the same evaluation. This method is inefficient because a gene will get credit for the contribution of all the other genes as well. Accurately measuring the fitness of individual genes in such a large search space requires many trials. This paper instead proposes turning this single complex search problem into a multi-agent search problem, where each agent has the simpler task of discovering a suitable gene. Gene-specific evaluation functions can then be created that have better theoretical properties than a single evaluation function over all genes. This method is tested in the difficult double-pole balancing problem, showing that agents using gene-specific evaluation functions can create a successful control policy in 20 percent fewer trials than the best existing genetic algorithms. The method is extended to more distributed problems, achieving 95 percent performance gains over tradition methods in the multi-rover domain.

  4. Reference databases for taxonomic assignment in metagenomics.

    PubMed

    Santamaria, Monica; Fosso, Bruno; Consiglio, Arianna; De Caro, Giorgio; Grillo, Giorgio; Licciulli, Flavio; Liuni, Sabino; Marzano, Marinella; Alonso-Alemany, Daniel; Valiente, Gabriel; Pesole, Graziano

    2012-11-01

    Metagenomics is providing an unprecedented access to the environmental microbial diversity. The amplicon-based metagenomics approach involves the PCR-targeted sequencing of a genetic locus fitting different features. Namely, it must be ubiquitous in the taxonomic range of interest, variable enough to discriminate between different species but flanked by highly conserved sequences, and of suitable size to be sequenced through next-generation platforms. The internal transcribed spacers 1 and 2 (ITS1 and ITS2) of the ribosomal DNA operon and one or more hyper-variable regions of 16S ribosomal RNA gene are typically used to identify fungal and bacterial species, respectively. In this context, reliable reference databases and taxonomies are crucial to assign amplicon sequence reads to the correct phylogenetic ranks. Several resources provide consistent phylogenetic classification of publicly available 16S ribosomal DNA sequences, whereas the state of ribosomal internal transcribed spacers reference databases is notably less advanced. In this review, we aim to give an overview of existing reference resources for both types of markers, highlighting strengths and possible shortcomings of their use for metagenomics purposes. Moreover, we present a new database, ITSoneDB, of well annotated and phylogenetically classified ITS1 sequences to be used as a reference collection in metagenomic studies of environmental fungal communities. ITSoneDB is available for download and browsing at http://itsonedb.ba.itb.cnr.it/.

  5. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision,...

  6. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision,...

  7. 12 CFR Appendix Ms-2 to Part 1024 - Notice of Assignment, Sale, or Transfer of Servicing Rights

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Notice of Assignment, Sale, or Transfer of Servicing Rights MS Appendix MS-2 to Part 1024 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION REAL ESTATE SETTLEMENT PROCEDURES ACT (REGULATION X) Pt. 1024, App. MS-2 Appendix MS-2 to Part...

  8. 12 CFR Appendix Ms-2 to Part 1024 - Notice of Assignment, Sale, or Transfer of Servicing Rights

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Notice of Assignment, Sale, or Transfer of Servicing Rights MS Appendix MS-2 to Part 1024 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION REAL ESTATE SETTLEMENT PROCEDURES ACT (REGULATION X) Pt. 1024, App. MS-2 Appendix MS-2 to Part...

  9. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision,...

  10. Why the Rhetoric of CS Programming Assignments Matters

    NASA Astrophysics Data System (ADS)

    Wolfe, Joanna

    2004-06-01

    Despite the multiple potential benefits of asking students working on programming tasks to consider human factors, most programming assignments narrowly focus on technical details and requirements. Female students in particular may be attracted to assignments that emphasize human as well as technical factors. To assess how students respond to changes in the rhetorical presentation of programming instructions, 81 students completed questionnaires evaluating different assignment instructions. Students generally perceived assignments emphasizing real-world contexts and users as more motivating and enjoyable to program than those that did not emphasize human factors. Moreover, when asked what makes a "good" programming assignment, over half of the students volunteered that they looked for assignments stressing a real-world purpose, use or application.

  11. 46 CFR 2.85-1 - Assignment of load lines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Assignment of load lines. 2.85-1 Section 2.85-1 Shipping... Lines § 2.85-1 Assignment of load lines. Most U.S. vessels, and foreign vessels in U.S. waters are required to have load line assignments in accordance with 46 U.S.C. Chapter 51. The load lines marks,...

  12. A New Secondary Structure Assignment Algorithm Using Cα Backbone Fragments

    PubMed Central

    Cao, Chen; Wang, Guishen; Liu, An; Xu, Shutan; Wang, Lincong; Zou, Shuxue

    2016-01-01

    The assignment of secondary structure elements in proteins is a key step in the analysis of their structures and functions. We have developed an algorithm, SACF (secondary structure assignment based on Cα fragments), for secondary structure element (SSE) assignment based on the alignment of Cα backbone fragments with central poses derived by clustering known SSE fragments. The assignment algorithm consists of three steps: First, the outlier fragments on known SSEs are detected. Next, the remaining fragments are clustered to obtain the central fragments for each cluster. Finally, the central fragments are used as a template to make assignments. Following a large-scale comparison of 11 secondary structure assignment methods, SACF, KAKSI and PROSS are found to have similar agreement with DSSP, while PCASSO agrees with DSSP best. SACF and PCASSO show preference to reducing residues in N and C cap regions, whereas KAKSI, P-SEA and SEGNO tend to add residues to the terminals when DSSP assignment is taken as standard. Moreover, our algorithm is able to assign subtle helices (310-helix, π-helix and left-handed helix) and make uniform assignments, as well as to detect rare SSEs in β-sheets or long helices as outlier fragments from other programs. The structural uniformity should be useful for protein structure classification and prediction, while outlier fragments underlie the structure–function relationship. PMID:26978354

  13. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... assigned to two or more persons in the alternative, for example, “John B. Smith or Mrs. Mary J. Smith” or “John B. Smith or Mrs. Mary J. Smith or the survivor,” may be assigned by one of them at maturity or... the names of or assigned to two or more persons jointly, for example, “John B. Smith and Mrs. Mary...

  14. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... assigned to two or more persons in the alternative, for example, “John B. Smith or Mrs. Mary J. Smith” or “John B. Smith or Mrs. Mary J. Smith or the survivor,” may be assigned by one of them at maturity or... the names of or assigned to two or more persons jointly, for example, “John B. Smith and Mrs. Mary...

  15. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... assigned to two or more persons in the alternative, for example, “John B. Smith or Mrs. Mary J. Smith” or “John B. Smith or Mrs. Mary J. Smith or the survivor,” may be assigned by one of them at maturity or... the names of or assigned to two or more persons jointly, for example, “John B. Smith and Mrs. Mary...

  16. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... assigned to two or more persons in the alternative, for example, “John B. Smith or Mrs. Mary J. Smith” or “John B. Smith or Mrs. Mary J. Smith or the survivor,” may be assigned by one of them at maturity or... the names of or assigned to two or more persons jointly, for example, “John B. Smith and Mrs. Mary...

  17. 47 CFR 22.813 - Technical channel pair assignment criteria.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Technical channel pair assignment criteria. 22.813 Section 22.813 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER....813 Technical channel pair assignment criteria. The rules in this section establish...

  18. Nonrandom Assignment in ANCOVA: The Alternate Ranks Design

    ERIC Educational Resources Information Center

    Dalton, Starrett; Overall, John E.

    1977-01-01

    A specific form of nonrandom assignment to treatment groups, the "alternate ranks" design, was investigated. This design eliminates the possibility of a correlation between the covariate and the treatment, and rules out experimenter bias in assignment of subjects to groups. (Editor)

  19. On the Use of Writing Assignments in Intermediate Microeconomic Theory

    ERIC Educational Resources Information Center

    O'Neill, Patrick B.

    2009-01-01

    A typical writing assignment in upper level required courses is a term paper. However many economics majors, particularly those in business schools, need to develop skill at writing shorter pieces. In this paper I describe numerous examples of shorter writing assignments that I have incorporated into an Intermediate Microeconomic Theory course.…

  20. Students' Evaluation of Writing Assignments in an Abnormal Psychology Course.

    ERIC Educational Resources Information Center

    Procidano, Mary E.

    1991-01-01

    Presents a study in which students in an abnormal psychology class rated the usefulness of drafts for two writing assignments. Reports that a research proposal was more effective than a case study in generating interest in psychology and opportunity for creativity. Concludes that writing assignments should reflect important aspects of a…

  1. 44 CFR 323.5 - Assignment of resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Assignment of resources. 323.5... HOMELAND SECURITY PREPAREDNESS GUIDANCE ON PRIORITY USE OF RESOURCES IN IMMEDIATE POST ATTACK PERIOD (DMO-4) § 323.5 Assignment of resources. Resources required for essential uses, including manpower, will...

  2. 44 CFR 323.5 - Assignment of resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Assignment of resources. 323... OF HOMELAND SECURITY PREPAREDNESS GUIDANCE ON PRIORITY USE OF RESOURCES IN IMMEDIATE POST ATTACK PERIOD (DMO-4) § 323.5 Assignment of resources. Resources required for essential uses, including...

  3. 44 CFR 323.5 - Assignment of resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Assignment of resources. 323... OF HOMELAND SECURITY PREPAREDNESS GUIDANCE ON PRIORITY USE OF RESOURCES IN IMMEDIATE POST ATTACK PERIOD (DMO-4) § 323.5 Assignment of resources. Resources required for essential uses, including...

  4. 48 CFR 208.7006 - Coordinated acquisition assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... assignments. 208.7006 Section 208.7006 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Coordinated Acquisition 208.7006 Coordinated acquisition assignments. See PGI 208.7006 for coordinated...

  5. Exploring Mathematics outside the Classroom through the Field Trip Assignment

    ERIC Educational Resources Information Center

    Munakata, Mika

    2005-01-01

    This article describes the Field Trip Assignment, which was developed for a mathematics modeling course for prospective teachers. The objective of the assignment was to motivate students to make connections between mathematics and real-life phenomena while considering how to make those connections explicit to their future students. For the Field…

  6. Automating Formative and Summative Feedback for Individualised Assignments

    ERIC Educational Resources Information Center

    Hamilton, Ian Robert

    2009-01-01

    Purpose: The purpose of this paper is to report on the rationale behind the use of a unique paper-based individualised accounting assignment, which automated the provision to students of immediate formative and timely summative feedback. Design/methodology/approach: As students worked towards completing their assignment, the package provided…

  7. 42 CFR 425.402 - Basic assignment methodology.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Basic assignment methodology. 425.402 Section 425.402 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES....402 Basic assignment methodology. (a) CMS employs the following step-wise methodology to...

  8. 42 CFR 425.402 - Basic assignment methodology.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Basic assignment methodology. 425.402 Section 425.402 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES....402 Basic assignment methodology. (a) CMS employs the following step-wise methodology to...

  9. 42 CFR 425.402 - Basic assignment methodology.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Basic assignment methodology. 425.402 Section 425.402 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES....402 Basic assignment methodology. (a) CMS employs the following step-wise methodology to...

  10. 14 CFR 1245.109 - Assignment of title to NASA.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title...

  11. 14 CFR 1245.109 - Assignment of title to NASA.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title...

  12. 14 CFR 1245.109 - Assignment of title to NASA.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title...

  13. 14 CFR 1245.109 - Assignment of title to NASA.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title...

  14. 76 FR 34658 - The Internet Assigned Numbers Authority (IANA) Functions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... of Inquiry, Request for Comments on the Internet Assigned Numbers Authority (IANA) Functions, 76 FR 10569 (Feb. 25, 2011), available at http://www.ntia.doc.gov/frnotices/2011/fr_ianafunctionsnoi_02252011... National Telecommunications and Information Administration The Internet Assigned Numbers Authority...

  15. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements....

  16. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements....

  17. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements....

  18. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements....

  19. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements....

  20. 46 CFR 44.05-20 - Conditions of assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... be made for freeing decks of water, the slots are to be located so as to have maximum efficacy. (b... to satisfy the assigning authority that no unusual hazards will be experienced. (c) Self-propelled barges. The conditions of assignment for self-propelled cargo barges carrying cargo under decks shall...