Sample records for act nuclear indemnification

  1. 14 CFR 15.113 - Indemnification agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Indemnification agreements. 15.113 Section... Federal Aviation Act of 1958 § 15.113 Indemnification agreements. (a) Upon a finding of the Administrator... States Department of Justice, the FAA will promptly enter into an indemnification agreement providing for...

  2. 14 CFR 15.113 - Indemnification agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Indemnification agreements. 15.113 Section... Federal Aviation Act of 1958 § 15.113 Indemnification agreements. (a) Upon a finding of the Administrator... States Department of Justice, the FAA will promptly enter into an indemnification agreement providing for...

  3. 14 CFR 15.113 - Indemnification agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Indemnification agreements. 15.113 Section... Federal Aviation Act of 1958 § 15.113 Indemnification agreements. (a) Upon a finding of the Administrator... States Department of Justice, the FAA will promptly enter into an indemnification agreement providing for...

  4. 78 FR 56868 - Adjustment of Indemnification for Inflation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... subsection 170d. of the Atomic Energy Act of 1954 (AEA), 42 U.S.C. 2210d., commonly known as the Price... DEPARTMENT OF ENERGY Adjustment of Indemnification for Inflation AGENCY: Office of General Counsel, U.S Department of Energy. ACTION: Notice of adjusted indemnification amount. SUMMARY: The Department...

  5. 17 CFR 229.510 - (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities. 229.510 Section 229.510 Commodity and...-REGULATION S-K Registration Statement and Prospectus Provisions § 229.510 (Item 510) Disclosure of Commission...

  6. 17 CFR 229.510 - (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities. 229.510 Section 229.510 Commodity and...-REGULATION S-K Registration Statement and Prospectus Provisions § 229.510 (Item 510) Disclosure of Commission...

  7. 17 CFR 229.510 - (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false (Item 510) Disclosure of Commission position on indemnification for Securities Act liabilities. 229.510 Section 229.510 Commodity and...-REGULATION S-K Registration Statement and Prospectus Provisions § 229.510 (Item 510) Disclosure of Commission...

  8. 32 CFR 174.15 - Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993. 174.15 Section 174.15 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CLOSURES AND REALIGNMENT REVITALIZING BASE CLOSURE COMMUNITIES AND ADDRESSING IMPACTS OF REALIGNMENT...

  9. 32 CFR 174.15 - Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993. 174.15 Section 174.15 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CLOSURES AND REALIGNMENT REVITALIZING BASE CLOSURE COMMUNITIES AND ADDRESSING IMPACTS OF REALIGNMENT...

  10. 32 CFR 174.15 - Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993. 174.15 Section 174.15 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CLOSURES AND REALIGNMENT REVITALIZING BASE CLOSURE COMMUNITIES AND ADDRESSING IMPACTS OF REALIGNMENT...

  11. 32 CFR 174.15 - Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993. 174.15 Section 174.15 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CLOSURES AND REALIGNMENT REVITALIZING BASE CLOSURE COMMUNITIES AND ADDRESSING IMPACTS OF REALIGNMENT...

  12. 32 CFR 174.15 - Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Indemnification under Section 330 of the National Defense Authorization Act for Fiscal Year 1993. 174.15 Section 174.15 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CLOSURES AND REALIGNMENT REVITALIZING BASE CLOSURE COMMUNITIES AND ADDRESSING IMPACTS OF REALIGNMENT...

  13. 14 CFR 15.113 - Indemnification agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15.113 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL... States Department of Justice, the FAA will promptly enter into an indemnification agreement providing for... reasonable attorney fees at a rate not to exceed that permitted under the Equal Access to Justice Act (5 U.S...

  14. 14 CFR 15.113 - Indemnification agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15.113 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL... States Department of Justice, the FAA will promptly enter into an indemnification agreement providing for... reasonable attorney fees at a rate not to exceed that permitted under the Equal Access to Justice Act (5 U.S...

  15. 12 CFR 1710.20 - Indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Indemnification. 1710.20 Section 1710.20 Banks and Banking OFFICE OF FEDERAL HOUSING ENTERPRISE OVERSIGHT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SAFETY AND SOUNDNESS CORPORATE GOVERNANCE Indemnification § 1710.20 Indemnification. (a) Safety...

  16. 48 CFR 950.7003 - Nuclear hazards indemnity.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Nuclear hazards indemnity... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7003 Nuclear hazards indemnity. (a) Section 170d. of the Atomic Energy Act, as amended, requires...

  17. 48 CFR 950.7003 - Nuclear hazards indemnity.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Nuclear hazards indemnity... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7003 Nuclear hazards indemnity. (a) Section 170d. of the Atomic Energy Act, as amended, requires...

  18. 48 CFR 950.7003 - Nuclear hazards indemnity.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Nuclear hazards indemnity... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7003 Nuclear hazards indemnity. (a) Section 170d. of the Atomic Energy Act, as amended, requires...

  19. 48 CFR 950.7003 - Nuclear hazards indemnity.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Nuclear hazards indemnity... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7003 Nuclear hazards indemnity. (a) Section 170d. of the Atomic Energy Act, as amended, requires...

  20. 48 CFR 950.7003 - Nuclear hazards indemnity.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Nuclear hazards indemnity... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7003 Nuclear hazards indemnity. (a) Section 170d. of the Atomic Energy Act, as amended, requires...

  1. 10 CFR 770.9 - What conditions apply to DOE indemnification of claims against a person or entity based on the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770.9 What conditions apply to... transfer of real property for economic development contains an indemnification provision, the person or... indemnification agreement if DOE determines that indemnification is essential for the purpose of facilitating...

  2. 12 CFR 701.33 - Reimbursement, insurance, and indemnification of officials and employees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... relevant provisions of the Model Business Corporation Act. A Federal credit union that elects to provide indemnification shall specify whether it will follow the relevant state law or the Model Business Corporation Act... Business Corporation Act, as specified. A charter or bylaw amendment must be approved by the National...

  3. 12 CFR 701.33 - Reimbursement, insurance, and indemnification of officials and employees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... relevant provisions of the Model Business Corporation Act. A Federal credit union that elects to provide indemnification shall specify whether it will follow the relevant state law or the Model Business Corporation Act... extent such insurance is permitted by the applicable state law or the Model Business Corporation Act. (4...

  4. 7 CFR 2201.31 - Indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Indemnification. 2201.31 Section 2201.31 Agriculture Regulations of the Department of Agriculture (Continued) LOCAL TELEVISION LOAN GUARANTEE BOARD LOCAL TELEVISION LOAN GUARANTEE PROGRAM-PROGRAM REGULATIONS Loan Guarantees § 2201.31 Indemnification. (a) The...

  5. 36 CFR 292.70 - Indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Indemnification. 292.70 Section 292.70 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Other Provisions § 292.70 Indemnification. The owner...

  6. 36 CFR 292.70 - Indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Indemnification. 292.70 Section 292.70 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Other Provisions § 292.70 Indemnification. The owner...

  7. 36 CFR 292.70 - Indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Indemnification. 292.70 Section 292.70 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Other Provisions § 292.70 Indemnification. The owner...

  8. 7 CFR 1.501 - Policy on employee indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Policy on employee indemnification. 1.501 Section 1.501 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Policy With Regard to Indemnification of Department of Agriculture Employees § 1.501 Policy on employee indemnification...

  9. 48 CFR 950.7006 - Statutory nuclear hazards indemnity agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Statutory nuclear hazards... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7006 Statutory nuclear hazards indemnity agreement. (a) The contract clause contained in 952...

  10. 48 CFR 950.7006 - Statutory nuclear hazards indemnity agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Statutory nuclear hazards... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7006 Statutory nuclear hazards indemnity agreement. (a) The contract clause contained in 952...

  11. 48 CFR 950.7006 - Statutory nuclear hazards indemnity agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Statutory nuclear hazards... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7006 Statutory nuclear hazards indemnity agreement. (a) The contract clause contained in 952...

  12. 48 CFR 950.7006 - Statutory nuclear hazards indemnity agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Statutory nuclear hazards... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7006 Statutory nuclear hazards indemnity agreement. (a) The contract clause contained in 952...

  13. 48 CFR 950.7006 - Statutory nuclear hazards indemnity agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Statutory nuclear hazards... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7006 Statutory nuclear hazards indemnity agreement. (a) The contract clause contained in 952...

  14. 12 CFR 704.20 - Limitations on golden parachute and indemnification payments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AFFECTING CREDIT UNIONS CORPORATE CREDIT UNIONS § 704.20 Limitations on golden parachute and indemnification... Employee Retirement Income Security Act of 1974, as amended (29 U.S.C. 1002(1)), or other usual and... corporate credit union either: (A) Recognizes compensation expense and accrues a liability for the benefit...

  15. 14 CFR 1274.941 - Insurance and indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Insurance and indemnification. 1274.941 Section 1274.941 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE... insurance for, or indemnification of, developers of experimental aerospace vehicles. Insurance and...

  16. 5 CFR 911.104 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Procedures for requesting an indemnification agreement. 911.104 Section 911.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... INDEMNIFICATION § 911.104 Procedures for requesting an indemnification agreement. When requesting an...

  17. 5 CFR 911.104 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Procedures for requesting an indemnification agreement. 911.104 Section 911.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... INDEMNIFICATION § 911.104 Procedures for requesting an indemnification agreement. When requesting an...

  18. 5 CFR 911.104 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Procedures for requesting an indemnification agreement. 911.104 Section 911.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... INDEMNIFICATION § 911.104 Procedures for requesting an indemnification agreement. When requesting an...

  19. 5 CFR 911.104 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Procedures for requesting an indemnification agreement. 911.104 Section 911.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... INDEMNIFICATION § 911.104 Procedures for requesting an indemnification agreement. When requesting an...

  20. 5 CFR 911.104 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Procedures for requesting an indemnification agreement. 911.104 Section 911.104 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... INDEMNIFICATION § 911.104 Procedures for requesting an indemnification agreement. When requesting an...

  1. 5 CFR 911.103 - Eligibility for indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Eligibility for indemnification. 911.103 Section 911.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.103 Eligibility...

  2. 5 CFR 911.105 - Terms of indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Terms of indemnification. 911.105 Section 911.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.105 Terms of...

  3. 5 CFR 911.103 - Eligibility for indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Eligibility for indemnification. 911.103 Section 911.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.103 Eligibility...

  4. 5 CFR 911.103 - Eligibility for indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Eligibility for indemnification. 911.103 Section 911.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.103 Eligibility...

  5. 5 CFR 911.105 - Terms of indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Terms of indemnification. 911.105 Section 911.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.105 Terms of...

  6. 5 CFR 911.105 - Terms of indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Terms of indemnification. 911.105 Section 911.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.105 Terms of...

  7. 5 CFR 911.103 - Eligibility for indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Eligibility for indemnification. 911.103 Section 911.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.103 Eligibility...

  8. 5 CFR 911.103 - Eligibility for indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Eligibility for indemnification. 911.103 Section 911.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.103 Eligibility...

  9. 5 CFR 911.105 - Terms of indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Terms of indemnification. 911.105 Section 911.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.105 Terms of...

  10. 5 CFR 911.105 - Terms of indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Terms of indemnification. 911.105 Section 911.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.105 Terms of...

  11. 32 CFR 516.32 - Requests for indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Individual Liability § 516.32 Requests for indemnification. (a) Policy...

  12. 32 CFR 516.32 - Requests for indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

  13. 32 CFR 516.32 - Requests for indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

  14. 32 CFR 516.32 - Requests for indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

  15. 32 CFR 516.32 - Requests for indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Requests for indemnification. 516.32 Section 516.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES... allied papers. (c) Supervisory and SJA procedures. The request for indemnification will be submitted...

  16. 48 CFR 235.070 - Indemnification against unusually hazardous risks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Indemnification against unusually hazardous risks. 235.070 Section 235.070 Federal Acquisition Regulations System DEFENSE... DEVELOPMENT CONTRACTING 235.070 Indemnification against unusually hazardous risks. ...

  17. 12 CFR 7.2014 - Indemnification of institution-affiliated parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Indemnification of institution-affiliated parties. 7.2014 Section 7.2014 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Corporate Practices § 7.2014 Indemnification of institution-affiliated...

  18. 75 FR 51986 - Convention on Supplementary Compensation for Nuclear Damage Contingent Cost Allocation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... period also supports DOE's interest in obtaining detailed and comprehensive commentary from nuclear suppliers and other interested stakeholders. DOE is hereby extending the comment period to October 27, 2010...- Anderson Act indemnification. The NOI requested public comment from interested persons regarding specific...

  19. 12 CFR 239.40 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Indemnification of directors, officers and employees. 239.40 Section 239.40 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification...

  20. 12 CFR 239.40 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Indemnification of directors, officers and employees. 239.40 Section 239.40 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification...

  1. 12 CFR 239.40 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Indemnification of directors, officers and employees. 239.40 Section 239.40 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification...

  2. 48 CFR 627.203 - Patent indemnification of Government by contractor.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Patent indemnification of Government by contractor. 627.203 Section 627.203 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents 627.203 Patent indemnification of...

  3. 48 CFR 627.203 - Patent indemnification of Government by contractor.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Patent indemnification of Government by contractor. 627.203 Section 627.203 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patents 627.203 Patent indemnification of...

  4. 48 CFR 250.104-3-70 - Indemnification under contracts involving both research and development and other work.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... contracts involving both research and development and other work. 250.104-3-70 Section 250.104-3-70 Federal... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 250.104-3-70 Indemnification under contracts involving both research and development and other work. When...

  5. 7 CFR 1980.308 - Full faith and credit and indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 14 2013-01-01 2013-01-01 false Full faith and credit and indemnification. 1980.308... Full faith and credit and indemnification. (a) Full faith and credit. The loan note guarantee constitutes an obligation supported by the full faith and credit of the United States and is incontestable...

  6. 7 CFR 1980.308 - Full faith and credit and indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false Full faith and credit and indemnification. 1980.308... Full faith and credit and indemnification. (a) Full faith and credit. The loan note guarantee constitutes an obligation supported by the full faith and credit of the United States and is incontestable...

  7. 7 CFR 1980.308 - Full faith and credit and indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Full faith and credit and indemnification. 1980.308... Full faith and credit and indemnification. (a) Full faith and credit. The loan note guarantee constitutes an obligation supported by the full faith and credit of the United States and is incontestable...

  8. 48 CFR 1850.403-1 - Indemnification requests. (NASA supplements paragraph (a))

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Indemnification requests. (NASA supplements paragraph (a)) 1850.403-1 Section 1850.403-1 Federal Acquisition Regulations System... Residual Powers 1850.403-1 Indemnification requests. (NASA supplements paragraph (a)) (a) Contractor...

  9. 48 CFR 1850.403-1 - Indemnification requests. (NASA supplements paragraph (a))

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Indemnification requests. (NASA supplements paragraph (a)) 1850.403-1 Section 1850.403-1 Federal Acquisition Regulations System... Residual Powers 1850.403-1 Indemnification requests. (NASA supplements paragraph (a)) (a) Contractor...

  10. 7 CFR 1726.255 - Prior approved contract modifications related to indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES... indemnification. (a) As an alternative to the indemnification provision required in RUS standard construction..., indemnify, and hold harmless Owner and Owner's directors, officers, and employees from all claims, causes of...

  11. 7 CFR 1726.255 - Prior approved contract modifications related to indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES... indemnification. (a) As an alternative to the indemnification provision required in RUS standard construction..., indemnify, and hold harmless Owner and Owner's directors, officers, and employees from all claims, causes of...

  12. 7 CFR 1726.255 - Prior approved contract modifications related to indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES... indemnification. (a) As an alternative to the indemnification provision required in RUS standard construction..., indemnify, and hold harmless Owner and Owner's directors, officers, and employees from all claims, causes of...

  13. 7 CFR 1726.255 - Prior approved contract modifications related to indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES... indemnification. (a) As an alternative to the indemnification provision required in RUS standard construction..., indemnify, and hold harmless Owner and Owner's directors, officers, and employees from all claims, causes of...

  14. 34 CFR 60.2 - What procedures apply to requests for indemnification?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DEPARTMENT OF EDUCATION EMPLOYEES § 60.2 What procedures apply to requests for indemnification? (a) When an employee of the Department of Education becomes aware that an action has been filed against the employee in... 34 Education 1 2010-07-01 2010-07-01 false What procedures apply to requests for indemnification...

  15. 13 CFR 302.19 - Indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Indemnification. 302.19 Section 302.19 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE... permitted by law, a Recipient shall indemnify and hold EDA harmless from any liability that EDA may incur...

  16. 36 CFR 228.110 - Indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Indemnification. 228.110 Section 228.110 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE MINERALS Oil... United States for: (a) Injury, loss or damage, including fire suppression costs, which the United States...

  17. 47 CFR 76.108 - Indemnification contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Indemnification contracts. 76.108 Section 76.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... indemnify a cable system for liability resulting from failure to delete programming in accordance with the...

  18. 47 CFR 76.108 - Indemnification contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indemnification contracts. 76.108 Section 76.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... indemnify a cable system for liability resulting from failure to delete programming in accordance with the...

  19. 47 CFR 76.125 - Indemnification contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Indemnification contracts. 76.125 Section 76.125 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... programming in accordance with the provisions of this Subpart unless the licensee has a reasonable basis for...

  20. 47 CFR 76.125 - Indemnification contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indemnification contracts. 76.125 Section 76.125 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... programming in accordance with the provisions of this Subpart unless the licensee has a reasonable basis for...

  1. 48 CFR 1850.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Special procedures for unusually hazardous or nuclear risks. 1850.104-3 Section 1850.104-3 Federal Acquisition Regulations System... nuclear risks. (a) Indemnification requests. (1) Contractor indemnification requests must be submitted to...

  2. 48 CFR 1850.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Special procedures for unusually hazardous or nuclear risks. 1850.104-3 Section 1850.104-3 Federal Acquisition Regulations System... nuclear risks. (a) Indemnification requests. (1) Contractor indemnification requests must be submitted to...

  3. 10 CFR 770.9 - What conditions apply to DOE indemnification of claims against a person or entity based on the...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false What conditions apply to DOE indemnification of claims... pollutant or contaminant attributable to DOE? 770.9 Section 770.9 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770.9 What conditions apply to...

  4. 10 CFR 770.9 - What conditions apply to DOE indemnification of claims against a person or entity based on the...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false What conditions apply to DOE indemnification of claims... pollutant or contaminant attributable to DOE? 770.9 Section 770.9 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770.9 What conditions apply to...

  5. 12 CFR 239.31 - Indemnification; employment contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Indemnification; employment contracts. 239.31 Section 239.31 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.31...

  6. 12 CFR 239.31 - Indemnification; employment contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Indemnification; employment contracts. 239.31 Section 239.31 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.31...

  7. 12 CFR 239.31 - Indemnification; employment contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Indemnification; employment contracts. 239.31 Section 239.31 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.31...

  8. 10 CFR 770.10 - When must a person or entity, who wishes to contest a DOE denial of request for indemnification...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false When must a person or entity, who wishes to contest a DOE denial of request for indemnification of a claim, begin legal action? 770.10 Section 770.10 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770...

  9. 10 CFR 770.10 - When must a person or entity, who wishes to contest a DOE denial of request for indemnification...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false When must a person or entity, who wishes to contest a DOE denial of request for indemnification of a claim, begin legal action? 770.10 Section 770.10 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770...

  10. 10 CFR 770.10 - When must a person or entity, who wishes to contest a DOE denial of request for indemnification...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false When must a person or entity, who wishes to contest a DOE denial of request for indemnification of a claim, begin legal action? 770.10 Section 770.10 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770...

  11. 10 CFR 770.10 - When must a person or entity, who wishes to contest a DOE denial of request for indemnification...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false When must a person or entity, who wishes to contest a DOE denial of request for indemnification of a claim, begin legal action? 770.10 Section 770.10 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770...

  12. 10 CFR 770.10 - When must a person or entity, who wishes to contest a DOE denial of request for indemnification...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false When must a person or entity, who wishes to contest a DOE denial of request for indemnification of a claim, begin legal action? 770.10 Section 770.10 Energy DEPARTMENT OF ENERGY TRANSFER OF REAL PROPERTY AT DEFENSE NUCLEAR FACILITIES FOR ECONOMIC DEVELOPMENT § 770...

  13. 32 CFR 99.5 - Eligibility for indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Eligibility for indemnification. 99.5 Section 99.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND... history record information to the DoD, OPM, or CIA. (b) A State or locality is also eligible for an...

  14. 32 CFR 99.9 - Terms of indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Terms of indemnification. 99.9 Section 99.9 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA for the purposes...

  15. 32 CFR 99.9 - Terms of indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Terms of indemnification. 99.9 Section 99.9 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA for the purposes...

  16. 32 CFR 99.5 - Eligibility for indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Eligibility for indemnification. 99.5 Section 99.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND... history record information to the DoD, OPM, or CIA. (b) A State or locality is also eligible for an...

  17. 32 CFR 99.9 - Terms of indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Terms of indemnification. 99.9 Section 99.9 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA for the purposes...

  18. 32 CFR 99.5 - Eligibility for indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Eligibility for indemnification. 99.5 Section 99.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND... history record information to the DoD, OPM, or CIA. (b) A State or locality is also eligible for an...

  19. 32 CFR 99.9 - Terms of indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Terms of indemnification. 99.9 Section 99.9 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA for the purposes...

  20. 32 CFR 99.9 - Terms of indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Terms of indemnification. 99.9 Section 99.9 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA for the purposes...

  1. 32 CFR 99.5 - Eligibility for indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Eligibility for indemnification. 99.5 Section 99.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND... history record information to the DoD, OPM, or CIA. (b) A State or locality is also eligible for an...

  2. 32 CFR 99.5 - Eligibility for indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Eligibility for indemnification. 99.5 Section 99.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND... history record information to the DoD, OPM, or CIA. (b) A State or locality is also eligible for an...

  3. 48 CFR 231.205-19 - Insurance and indemnification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

  4. 48 CFR 231.205-19 - Insurance and indemnification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

  5. 48 CFR 231.205-19 - Insurance and indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

  6. 48 CFR 231.205-19 - Insurance and indemnification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

  7. 48 CFR 231.205-19 - Insurance and indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

  8. 42 CFR 422.212 - Limitations on provider indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Limitations on provider indemnification. 422.212 Section 422.212 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Relationships With Providers § 422.212...

  9. 37 CFR 104.32 - Procedure for requesting indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Procedure for requesting indemnification. 104.32 Section 104.32 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK... the circumstances of the incident giving rise to the court action or proceeding. (b)(1) An employee...

  10. 12 CFR 7.2014 - Indemnification of institution-affiliated parties.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... reasonable and consistent with the requirements of 12 U.S.C. 1828(k) and the implementing regulations thereunder. The term “institution-affiliated party” has the same meaning as set forth at 12 U.S.C. 1813(u... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Indemnification of institution-affiliated...

  11. 12 CFR 7.2014 - Indemnification of institution-affiliated parties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... reasonable and consistent with the requirements of 12 U.S.C. 1828(k) and the implementing regulations thereunder. The term “institution-affiliated party” has the same meaning as set forth at 12 U.S.C. 1813(u... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Indemnification of institution-affiliated...

  12. 12 CFR 7.2014 - Indemnification of institution-affiliated parties.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... reasonable and consistent with the requirements of 12 U.S.C. 1828(k) and the implementing regulations thereunder. The term “institution-affiliated party” has the same meaning as set forth at 12 U.S.C. 1813(u... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Indemnification of institution-affiliated...

  13. 48 CFR 235.070-1 - Indemnification under research and development contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... research and development contracts. 235.070-1 Section 235.070-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.070-1 Indemnification under research and development contracts. (a...

  14. 12 CFR 145.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... paragraph (b) of this section is subject to and qualified by 12 U.S.C. 1821(k). ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Indemnification of directors, officers and employees. 145.121 Section 145.121 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY...

  15. 12 CFR 145.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... paragraph (b) of this section is subject to and qualified by 12 U.S.C. 1821(k). ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Indemnification of directors, officers and employees. 145.121 Section 145.121 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY...

  16. 12 CFR 145.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... paragraph (b) of this section is subject to and qualified by 12 U.S.C. 1821(k). ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Indemnification of directors, officers and employees. 145.121 Section 145.121 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY...

  17. 32 CFR 99.7 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Procedures for requesting an indemnification agreement. 99.7 Section 99.7 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA; and (b) Append to...

  18. 32 CFR 99.7 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Procedures for requesting an indemnification agreement. 99.7 Section 99.7 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA; and (b) Append to...

  19. 32 CFR 99.7 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Procedures for requesting an indemnification agreement. 99.7 Section 99.7 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA; and (b) Append to...

  20. 32 CFR 99.7 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Procedures for requesting an indemnification agreement. 99.7 Section 99.7 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA; and (b) Append to...

  1. 32 CFR 99.7 - Procedures for requesting an indemnification agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Procedures for requesting an indemnification agreement. 99.7 Section 99.7 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... prohibiting the disclosure of criminal history record information to the DoD, OPM, or CIA; and (b) Append to...

  2. 12 CFR 545.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... qualified by 12 U.S.C. 1821(k). [54 FR 49492, Nov. 30, 1989, as amended at 56 FR 59866, Nov. 26, 1991; 60 FR... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Indemnification of directors, officers and employees. 545.121 Section 545.121 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE...

  3. 12 CFR 545.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... qualified by 12 U.S.C. 1821(k). [54 FR 49492, Nov. 30, 1989, as amended at 56 FR 59866, Nov. 26, 1991; 60 FR... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Indemnification of directors, officers and employees. 545.121 Section 545.121 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE...

  4. 12 CFR 545.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... qualified by 12 U.S.C. 1821(k). [54 FR 49492, Nov. 30, 1989, as amended at 56 FR 59866, Nov. 26, 1991; 60 FR... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Indemnification of directors, officers and employees. 545.121 Section 545.121 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE...

  5. 12 CFR 545.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... qualified by 12 U.S.C. 1821(k). [54 FR 49492, Nov. 30, 1989, as amended at 56 FR 59866, Nov. 26, 1991; 60 FR... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Indemnification of directors, officers and employees. 545.121 Section 545.121 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE...

  6. 12 CFR 545.121 - Indemnification of directors, officers and employees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... qualified by 12 U.S.C. 1821(k). [54 FR 49492, Nov. 30, 1989, as amended at 56 FR 59866, Nov. 26, 1991; 60 FR... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Indemnification of directors, officers and employees. 545.121 Section 545.121 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE...

  7. 34 CFR 60.1 - What are the policies of the Department regarding indemnification?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DEPARTMENT OF EDUCATION EMPLOYEES § 60.1 What are the policies of the Department regarding indemnification? (a)(1) The Department of Education may indemnify, in whole or in part, an employee for any verdict, judgment, or other monetary award rendered against the employee if— (i) The conduct giving rise to the...

  8. 34 CFR 60.1 - What are the policies of the Department regarding indemnification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., judgment, or other monetary award rendered against the employee if— (i) The conduct giving rise to the... (ii) The indemnification is in the interest of the United States, as determined by the Secretary. (2... giving rise to the personal damage claim occurred within the scope of employment; and (ii) The settlement...

  9. 78 FR 80382 - Federal Acquisition Regulation; Terms of Service and Open-Ended Indemnification and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ..., Sequence 1] RIN 9000-AM45 Federal Acquisition Regulation; Terms of Service and Open-Ended Indemnification... Acquisition Regulation (FAR) to address concerns raised in an opinion from the U.S. Department of Justice (DOJ... acquisitions for social media applications. DATES: Effective: December 31, 2013. FOR FURTHER INFORMATION...

  10. Insurance and indemnification implications of future space projects

    NASA Technical Reports Server (NTRS)

    O'Brien, John E.

    1987-01-01

    NASA options regarding insurance and indemnification policies as they relate to NASA customers and contractors are described. The foundation for the discussion is the way in which NASA is planning to return the Space Shuttle fleet to safe flight as well as current U.S. policy concerning future uses of the Shuttle fleet. Issues discussed include: the nature of the Shuttle manifest; the policy regarding property damage or destruction; insurance against liability to third parties; the reduction of the scope of the risk to be insured; NASA as the insurer; a sharing arrangement between the user and NASA; and contractors and subcontractors involved in Shuttle operations.

  11. 48 CFR 950.7009 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Fees. 950.7009 Section 950.7009 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Nuclear Indemnification of DOE Contractors 950.7009 Fees. No fee will...

  12. Causation's nuclear future: applying proportional liability to the Price-Anderson Act.

    PubMed

    O'Connell, William D

    2014-11-01

    For more than a quarter century, public discourse has pushed the nuclear-power industry in the direction of heavier regulation and greater scrutiny, effectively halting construction of new reactors. By focusing on contemporary fear of significant accidents, such discourse begs the question of what the nation's court system would actually do should a major nuclear incident cause radiation-induced cancers. Congress's attempt to answer that question is the Price-Anderson Act, a broad statute addressing claims by the victims of a major nuclear accident. Lower courts interpreting the Act have repeatedly encountered a major stumbling block: it declares that judges must apply the antediluvian preponderance-of-the-evidence logic of state tort law, even though radiation science insists that the causes of radiation-induced cancers are more complex. After a major nuclear accident, the Act's paradoxically outdated rules for adjudicating "causation" would make post-incident compensation unworkable. This Note urges that nuclear-power-plant liability should not turn on eighteenth-century tort law. Drawing on modern scientific conclusions regarding the invariably "statistical" nature of cancer, this Note suggests a unitary federal standard for the Price-Anderson Act--that a defendant be deemed to have "caused" a plaintiff's injury in direct proportion to the increased risk of harm the defendant has imposed. This "proportional liability" rule would not only fairly evaluate the costs borne by injured plaintiffs and protect a reawakening nuclear industry from the prospect of bank-breaking litigation, but would prove workable with only minor changes to the Price-Anderson Act's standards of "injury" and "fault."

  13. 10 CFR 770.9 - What conditions apply to DOE indemnification of claims against a person or entity based on the...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... entity requesting indemnification for a particular claim must: (1) Notify the Field Office Manager in... Office Manager, or such other DOE official as the Field Office Manager designates, with evidence or proof of the claim; (3) Furnish the Field Office Manager, or such other DOE official as the Field Office...

  14. 10 CFR 770.9 - What conditions apply to DOE indemnification of claims against a person or entity based on the...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... entity requesting indemnification for a particular claim must: (1) Notify the Field Office Manager in... Office Manager, or such other DOE official as the Field Office Manager designates, with evidence or proof of the claim; (3) Furnish the Field Office Manager, or such other DOE official as the Field Office...

  15. Science, Society, and America's Nuclear Waste: The Nuclear Waste Policy Act, Unit 3. Teacher Guide. Second Edition.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 3 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to identify the key elements of the United States' nuclear waste dilemma and introduce the Nuclear Waste Policy Act and the role of the…

  16. 46 CFR 287.2 - Scope of section 511 of the Act and the regulations in this part.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... regulations prescribed in this part— (1) Apply to gain realized from the sale or loss of vessels, earnings... nonrecognition, for income and excess-profits tax purposes, of the gain realized from the sale or indemnification.... It also permits the accumulation of the proceeds of such sales or indemnification and of certain...

  17. 46 CFR 287.2 - Scope of section 511 of the Act and the regulations in this part.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... regulations prescribed in this part— (1) Apply to gain realized from the sale or loss of vessels, earnings... nonrecognition, for income and excess-profits tax purposes, of the gain realized from the sale or indemnification.... It also permits the accumulation of the proceeds of such sales or indemnification and of certain...

  18. 46 CFR 287.2 - Scope of section 511 of the Act and the regulations in this part.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... regulations prescribed in this part— (1) Apply to gain realized from the sale or loss of vessels, earnings... nonrecognition, for income and excess-profits tax purposes, of the gain realized from the sale or indemnification.... It also permits the accumulation of the proceeds of such sales or indemnification and of certain...

  19. 26 CFR 2.1-2 - Scope of section 511 of the Act and the regulations in this part.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... prescribed in this part— (i) Apply to gain realized from the sale or loss of vessels, earnings from the... and excess-profits tax purposes, of the gain realized from the sale or indemnification for loss of... permits the accumulation of the proceeds of such sales or indemnification and of certain earnings without...

  20. 26 CFR 2.1-2 - Scope of section 511 of the Act and the regulations in this part.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... prescribed in this part— (i) Apply to gain realized from the sale or loss of vessels, earnings from the... and excess-profits tax purposes, of the gain realized from the sale or indemnification for loss of... permits the accumulation of the proceeds of such sales or indemnification and of certain earnings without...

  1. Fast-acting nuclear reactor control device

    DOEpatents

    Kotlyar, Oleg M.; West, Phillip B.

    1993-01-01

    A fast-acting nuclear reactor control device for moving and positioning a fety control rod to desired positions within the core of the reactor between a run position in which the safety control rod is outside the reactor core, and a shutdown position in which the rod is fully inserted in the reactor core. The device employs a hydraulic pump/motor, an electric gear motor, and solenoid valve to drive the safety control rod into the reactor core through the entire stroke of the safety control rod. An overrunning clutch allows the safety control rod to freely travel toward a safe position in the event of a partial drive system failure.

  2. An Act of Scientific Creativity: Meitner, Frisch, and Nuclear Fission

    NASA Astrophysics Data System (ADS)

    Stuewer, Roger H.

    2002-04-01

    The dominant event that lay in the background to Werner Heisenberg's fateful meeting with Niels Bohr in occupied Copenhagen in September 1941 was the discovery and interpretation of nuclear fission three years earlier. Michael Frayn has explored that meeting in his play "Copenhagen" in an act of extraordinary literary creativity. In this talk I will explore Lise Meitner's and Otto Robert Frisch's interpretation of nuclear fission as an act of extraordinary scientific creativity. My aim is to understand historically how it was possible for Meitner and Frisch, and only Meitner and Frisch, to arrive at their interpretation as they talked and walked in the snow in the small Swedish village of Kungälv over the Christmas holidays in December 1938. This will require us to examine the history of the liquid-drop model of the nucleus over the preceding decade, from George Gamow's conception of that model in 1928, through Heisenberg and Carl Friedrich von Weizsäcker's extension of it between 1933 and 1936, and finally through Bohr's use of it in his theory of the compound nucleus between 1936 and 1938. We will see how Meitner and Frisch combined their different knowledge of these developments creatively to arrive at their momentous interpretation of nuclear fission.

  3. 13 CFR 114.101 - What do these regulations cover?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CLAIMS UNDER THE FEDERAL TORT CLAIMS ACT AND REPRESENTATION AND INDEMNIFICATION OF SBA EMPLOYEES... property, personal injury, or death arising from the negligent or wrongful act or omission of any SBA...

  4. Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein.

    PubMed

    Ariumi, Yasuo; Ego, Takeshi; Kaida, Atsushi; Matsumoto, Mikiko; Pandolfi, Pier Paolo; Shimotohno, Kunitada

    2003-03-20

    Several viruses target cellular promyelocytic leukemia (PML)-nuclear bodies (PML-NBs) to induce their disruption, marked morphological changes in these structures or the relocation to PML-NB components to the cytoplasm of infected cells. PML conversely interferes with viral replication. We demonstrate that PML acts as a coactivator for the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein without direct binding. Tax was identified within interchromatin granule clusters (IGCs)/RNA splicing bodies (SBs), not PML-NBs; Tax expression did not affect PML-NB formation. Moreover, PML and CBP/p300 cooperatively activated Tax-mediated HTLV-1-LTR-dependent gene expression. Interestingly, two PML mutants, PML-RAR and PMLDelta216-331, which fail to form PML-NBs, could also coactivate Tax-mediated trans-acting function but had no effect on retinoic acid receptor (RAR)- or p53-dependent gene expression. In contrast, SMRT (silencing mediator for retinoic acid and thyroid hormone receptors), a nuclear corepressor found within the matrix-associated deacetylase (MAD) nuclear body, relocalized into Tax-associated nuclear bodies upon coexpression with Tax. SMRT coactivated the trans-acting function of Tax through direct binding. Coexpression of SMRT and PML resulted in an additive activation of Tax trans-acting function. Thus, crosstalk between distinct nuclear bodies may control Tax function.

  5. Financial protection against nuclear hazards: thirty years' experience under the Price-Anderson Act

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rockett, L.R.; Hayn, I.

    1984-01-01

    The purpose of this study is to evaluate the operation of the Price-Anderson Act in the light of the last 10 years' experience and the changes that have occurred during that period both in the law and regulations and in the nuclear and insurance industries, and to provide an independent analysis of various proposals to extend or amend the Act prior to its 1987 expiration. The report does not analyze the impact of the Silkwood v. Kerr McGee Corp. decision. The five chapters cover historical background, financial protection under the Price-Anderson Act and in the absence of the Act, fundamentalmore » policy issues, and alternative proposals.« less

  6. 13 CFR 114.103 - Who may file a claim?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... THE FEDERAL TORT CLAIMS ACT AND REPRESENTATION AND INDEMNIFICATION OF SBA EMPLOYEES Administrative.... Death The executor, administrator, or legal representative of the decedent's estate, or any other person...

  7. 77 FR 63221 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... experiments on a locker insert to put into an experimental locker on board the ISS. The Space Act Agreement.... This has been true for indemnification of claims brought by employees. See, e.g., Howard Univ. v. Good...

  8. 75 FR 21605 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... depth federal safety management and oversight policies being developed by DOE and NNSA for defense... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... in the Sunshine Act'' (5 U.S.C. 552b), notice is hereby given of the Defense Nuclear Facilities...

  9. An overview of the draft for the amendment of 'nuclear materials and radioactive waste management act'

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huan Lin; Tai-Wei Lan; Min-Tsang Chang

    2013-07-01

    The 'Nuclear Materials and Radioactive Waste Management Act' (NMRWMA) in Taiwan has been in use since 2002. To promote further administrative efficiency and improve regulatory capacity, an amendment of the act has been initiated by the Atomic Energy Council (AEC). It is now being reviewed by outside experts and related communities so as to include the best understanding of risk management factors. For the future decommissioning challenges of nuclear facilities, the act is also being amended to comply with the regulatory requirements of the decommissioning mandates. Currently the Taiwan government is conducting government reorganization, and AEC will be reformed butmore » will remain as an independent regulatory body. AEC will then be capable of improving the regulatory capacity for facilitating licensing and inspection, ensuring operational safety, environmental protection and public involvement, and giving a more flexible administrative discretion, such as expending the margin of penalty. The amendment is also required to provide a formal legal basis for the Nuclear Backend Fund, and to mandate the waste producers to take responsibility for any final debt repayment. In addition, this amendment promotes measures to prevent accidents or emergencies concerning radioactive materials and facilities and procedures to reduce the impact and effect of any unexpected events. Furthermore, this amendment intends to implement the concept of information transparency and public participation so as to meet the public needs. Finally, radioactive waste final disposal tasks have to be completed by waste producers under the supervision of the AEC. (authors)« less

  10. 36 CFR 292.70 - Indemnification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and severally liable in accordance with Federal and State laws for indemnifying the United States for... incurred from fire suppression efforts, and environmental response actions and cleanup and abatement costs... operation. This includes acts or omissions covered by Federal, State, and local pollution control and...

  11. 36 CFR 292.70 - Indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and severally liable in accordance with Federal and State laws for indemnifying the United States for... incurred from fire suppression efforts, and environmental response actions and cleanup and abatement costs... operation. This includes acts or omissions covered by Federal, State, and local pollution control and...

  12. 10 CFR 1304.103 - Privacy Act inquiries.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... writing may be sent to: Privacy Act Officer, U.S. Nuclear Waste Technical Review Board, 2300 Clarendon... NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... contains a record pertaining to him or her may file a request in person or in writing, via the internet, or...

  13. Financial protection against nuclear hazards: thirty years' experience under the Price-Anderson Act

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1984-01-01

    Supplementing earlier reports on ways to provide financial protection against the potential hazards involved in the production of nuclear energy by analyzing the issues raised in the Silkwood v. Kerr-McGee Corporation decision, the author explores the impact of the case on the availability of funds to compensate the public and any increased exposure of the nuclear industry or the federal government to public liability. She concludes that the decision will have a significant impact on the day-to-day administration of claims, and could lead to higher premiums. The court would have to determine the priority given to claims in the eventmore » of a catastrophic accident, in which case the only significant impact would be under amendments to the Price-Anderson Act which resulted in elimination of its coverage or a substantial increase in or elimination of the limitation on liability.« less

  14. 78 FR 49262 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Meeting AGENCY: Defense Nuclear Facilities... given of the Defense Nuclear Facilities Safety Board's (Board) public meeting and hearing described... associated with continued operation of aging defense nuclear [[Page 49263

  15. 76 FR 26716 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Meeting AGENCY: Defense Nuclear Facilities... Defense Nuclear Facilities Safety Board's (Board) public meeting and hearing. FEDERAL REGISTER CITATIONS... Defense Nuclear Facilities Safety Board, Public Hearing Room, 625 Indiana Avenue, NW., Suite 300...

  16. 78 FR 4393 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... given of the Defense Nuclear Facilities Safety Board's (Board) public meeting and hearing described... Session II, the Board will receive testimony concerning safety at Pantex defense nuclear facilities. The...

  17. 77 FR 479 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... of the Defense Nuclear Facilities Safety Board's (Board) public hearing and meeting described below... Nuclear Facilities Safety Board, 625 Indiana Avenue NW., Suite 700, Washington, DC 20004-2901, (800) 788...

  18. 77 FR 48970 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... given of the Defense Nuclear Facilities Safety Board's (Board) public meeting and hearing described... (NNSA) efforts to mitigate risks to public and worker safety posed by aging defense nuclear facilities...

  19. 10 CFR 8.2 - Interpretation of Price-Anderson Act, section 170 of the Atomic Energy Act of 1954.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Interpretation of Price-Anderson Act, section 170 of the Atomic Energy Act of 1954. 8.2 Section 8.2 Energy NUCLEAR REGULATORY COMMISSION INTERPRETATIONS § 8.2... in Nuclear Energy 75 (1959). In the testimony before the Joint Committee last year, Professor Samuel...

  20. 10 CFR 8.2 - Interpretation of Price-Anderson Act, section 170 of the Atomic Energy Act of 1954.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Interpretation of Price-Anderson Act, section 170 of the Atomic Energy Act of 1954. 8.2 Section 8.2 Energy NUCLEAR REGULATORY COMMISSION INTERPRETATIONS § 8.2... in Nuclear Energy 75 (1959). In the testimony before the Joint Committee last year, Professor Samuel...

  1. 76 FR 11764 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... Defense Nuclear Facilities Safety Board's public hearing and meeting described below. Interested persons... the matters to be considered. TIME AND DATE OF MEETING: 9 a.m., March 31, 2011. PLACE: Defense Nuclear...

  2. Consequences of Regional Scale Nuclear Conflicts and Acts of Individual Nuclear Terrorism

    NASA Astrophysics Data System (ADS)

    Toon, O. B.; Turco, R. P.; Robock, A.; Bardeen, C.; Oman, L.; Stenchikov, G. L.

    2006-12-01

    The number of nuclear warheads in the world has fallen by about a factor of three since its peak in 1986. However, the potential exists for numerous regional nuclear arms races, and for a significant expansion in the number of nuclear weapons states. Eight countries are known to have nuclear weapons, 2 are constructing them, and an additional 32 nations already have the fissile material needed to build weapons if they so desire. Population and economic activity worldwide are congregated to an increasing extent in "megacities", which are ideal targets for nuclear weapons. We find that low yield weapons, which new nuclear powers are likely to construct, can produce 100 times as many fatalities and 100 times as much smoke from fires per kt yield as high-yield weapons, if they are targeted at city centers. A single low-yield nuclear detonation in an urban center could lead to more fatalities, in some cases by orders of magnitude, than have occurred in major historical conflicts. A regional war between the smallest current nuclear states involving 100 15-kt explosions (less than 0.1% of the explosive yield of the current global nuclear arsenal) could produce direct fatalities comparable to all of those worldwide in World War II (WW-II), or to those once estimated for a "counterforce" nuclear war between the superpowers. Portions of megacities attacked with nuclear devices or exposed to fallout of long-lived isotopes, through armed conflict or terrorism, would likely be abandoned indefinitely, with severe national and international implications. Smoke from urban firestorms in a regional war might induce significant climatic and ozone anomalies on global scales. While there are many uncertainties in the issues we discuss here, the major uncertainties are the type and scale of conflict that might occur. Each of these potential hazards deserves careful analysis by governments worldwide advised by a broad section of the world scientific community, as well as widespread

  3. 75 FR 56080 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... Facilities Safety Board's public hearing and meeting. FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: 75... INFORMATION: Brian Grosner, General Manager, Defense Nuclear Facilities Safety Board, 625 Indiana Avenue, NW...

  4. 75 FR 47236 - Golden Parachute and Indemnification Payments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... affairs of an insured credit union, or required to cease and desist from or take any affirmative action... desist from or take an affirmative action described in section 206 of the Federal Credit Union Act, 12 U... affirmative action described in section 206 of the Act (12 U.S.C.1786) with respect to the credit union. (2...

  5. 77 FR 59022 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0002] Sunshine Act Meeting AGENCY HOLDING THE MEETINGS: Nuclear Regulatory Commission. DATE: Weeks of September 24, October 1, 8, 15, 22, 29, 2012. [[Page 59023... of the Nuclear Materials Users and Decommissioning and Low-Level Waste Business Lines (Public Meeting...

  6. 38 CFR 14.667 - Claims payable.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... incident to the employee's service and his or her possession of the property was reasonable, useful, or... States. (4) Was not caused wholly or partly by the negligent act of claimant, the claimant's agent, or employee, and that the claimant has no right to indemnification for the loss or damage from other than the...

  7. 38 CFR 14.667 - Claims payable.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... incident to the employee's service and his or her possession of the property was reasonable, useful, or... States. (4) Was not caused wholly or partly by the negligent act of claimant, the claimant's agent, or employee, and that the claimant has no right to indemnification for the loss or damage from other than the...

  8. 38 CFR 14.667 - Claims payable.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... incident to the employee's service and his or her possession of the property was reasonable, useful, or... States. (4) Was not caused wholly or partly by the negligent act of claimant, the claimant's agent, or employee, and that the claimant has no right to indemnification for the loss or damage from other than the...

  9. 38 CFR 14.667 - Claims payable.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... incident to the employee's service and his or her possession of the property was reasonable, useful, or... States. (4) Was not caused wholly or partly by the negligent act of claimant, the claimant's agent, or employee, and that the claimant has no right to indemnification for the loss or damage from other than the...

  10. 38 CFR 14.667 - Claims payable.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... incident to the employee's service and his or her possession of the property was reasonable, useful, or... States. (4) Was not caused wholly or partly by the negligent act of claimant, the claimant's agent, or employee, and that the claimant has no right to indemnification for the loss or damage from other than the...

  11. 77 FR 13158 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0002] Sunshine Act Meeting Notice DATE: Weeks of March 5...-11-2 (Feb. 15, 2011), Docket No. 50-443-LR (Tentative) b. Entergy Nuclear Generation Co. and Entergy Nuclear Operations, Inc. (Pilgrim Nuclear Power Station), Commonwealth of Massachusetts' Notice of Appeal...

  12. 10 CFR 1304.103 - Privacy Act inquiries.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Privacy Act inquiries. 1304.103 Section 1304.103 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... Clarendon Blvd., Suite 1300; Arlington, VA. Requests should be marked “Privacy Act Request” on each page of...

  13. 10 CFR 1304.103 - Privacy Act inquiries.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Privacy Act inquiries. 1304.103 Section 1304.103 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... Clarendon Blvd., Suite 1300; Arlington, VA. Requests should be marked “Privacy Act Request” on each page of...

  14. 10 CFR 1304.103 - Privacy Act inquiries.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Privacy Act inquiries. 1304.103 Section 1304.103 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... Clarendon Blvd., Suite 1300; Arlington, VA. Requests should be marked “Privacy Act Request” on each page of...

  15. 10 CFR 1304.103 - Privacy Act inquiries.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Privacy Act inquiries. 1304.103 Section 1304.103 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... Clarendon Blvd., Suite 1300; Arlington, VA. Requests should be marked “Privacy Act Request” on each page of...

  16. 76 FR 17627 - Sunshine Act Meeting Postponed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-30

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Meeting Postponed AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Notice of public meeting postponement. SUMMARY: The Defense Nuclear Facilities Safety Board (Board) published a document in the Federal Register of March 3, 2011 (76 FR 11764...

  17. 77 FR 14007 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Meeting Notice Federal Register CITATION OF... THE MEETING: The Defense Nuclear Facilities Safety Board (Board) is expanding the matters to be.../ resolution of safety and technical issues across the defense nuclear facilities complex. Since this panel...

  18. 77 FR 18271 - Notice of Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    .... Affirmation Session (Public Meeting) (Tentative) a. FirstEnergy Nuclear Operating Co. (Davis-Besse Nuclear... NUCLEAR REGULATORY COMMISSION [NRC-2012-0002] Notice of Sunshine Act Meeting DATE: Weeks of March....m. Briefing on the Final Report of the Blue Ribbon Commission on America's Nuclear Future (Public...

  19. 10 CFR 1304.113 - Privacy Act training.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

  20. 10 CFR 1304.113 - Privacy Act training.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

  1. 10 CFR 1304.113 - Privacy Act training.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

  2. 10 CFR 1304.113 - Privacy Act training.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

  3. 10 CFR 1304.113 - Privacy Act training.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

  4. 75 FR 43495 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities..., structures, and components, and (5) safety-related design aspects of new facilities or modifications of existing facilities needed to deliver high-level waste feed. The Board will be prepared to accept any other...

  5. 77 FR 64835 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... NUCLEAR REGULATORY COMMISSION Sunshine Act Meeting AGENCY HOLDING THE MEETINGS: Nuclear Regulatory... webcast live at the Web address--www.nrc.gov. 9:30 a.m. Strategic Programmatic Overview of the Spent Fuel Storage and Transportation and Fuel Facilities Business Lines (Public Meeting) (Contact: Kevin Mattern...

  6. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

    PubMed

    Wacker, Stephan Armin; Alvarado, Cristobal; von Wichert, Götz; Knippschild, Uwe; Wiedenmann, Jörg; Clauss, Karen; Nienhaus, Gerd Ulrich; Hameister, Horst; Baumann, Bernd; Borggrefe, Tilman; Knöchel, Walter; Oswald, Franz

    2011-01-05

    The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear translocation of the Notch intracellular domain (NICD). In the nucleus, NICD binds to the recombination signal sequence-binding protein J (RBP-J)/CBF-1 transcription factor to induce expression of Notch target genes. Here, we report the identification and functional characterization of RBP-J interacting and tubulin associated (RITA) (C12ORF52) as a novel RBP-J/CBF-1-interacting protein. RITA is a highly conserved 36 kDa protein that, most interestingly, binds to tubulin in the cytoplasm and shuttles rapidly between cytoplasm and nucleus. This shuttling RITA exports RBP-J/CBF-1 from the nucleus. Functionally, we show that RITA can reverse a Notch-induced loss of primary neurogenesis in Xenopus laevis. Furthermore, RITA is able to downregulate Notch-mediated transcription. Thus, we propose that RITA acts as a negative modulator of the Notch signalling pathway, controlling the level of nuclear RBP-J/CBF-1, where its amounts are limiting.

  7. 77 FR 1089 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0002] Sunshine Act Meetings AGENCY: Agency Holding the Meetings: Nuclear Regulatory Commission DATES: Week of January 9, 2012. Place: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland. Status: Public and Closed. Additional Items To Be Considered: Week of January 9, 2012 Wednesday,...

  8. Swap Data Repository and Clearinghouse Indemnification Correction Act of 2012

    THOMAS, 112th Congress

    Rep. Dold, Robert J. [R-IL-10

    2012-03-21

    House - 05/09/2012 Reported (Amended) by the Committee on Financial Services. H. Rept. 112-471, Part I. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. Swap Data Repository and Clearinghouse Indemnification Correction Act of 2013

    THOMAS, 113th Congress

    Rep. Crawford, Eric A. "Rick" [R-AR-1

    2013-02-15

    Senate - 06/13/2013 Received in the Senate and Read twice and referred to the Committee on Agriculture, Nutrition, and Forestry. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  10. Cytokinin stabilizes WUSCHEL by acting on the protein domains required for nuclear enrichment and transcription.

    PubMed

    Snipes, Stephen A; Rodriguez, Kevin; DeVries, Aaron E; Miyawaki, Kaori N; Perales, Mariano; Xie, Mingtang; Reddy, G Venugopala

    2018-04-01

    Concentration-dependent transcriptional regulation and the spatial regulation of transcription factor levels are poorly studied in plant development. WUSCHEL, a stem cell-promoting homeodomain transcription factor, accumulates at a higher level in the rib meristem than in the overlying central zone, which harbors stem cells in the shoot apical meristems of Arabidopsis thaliana. The differential accumulation of WUSCHEL in adjacent cells is critical for the spatial regulation and levels of CLAVATA3, a negative regulator of WUSCHEL transcription. Earlier studies have revealed that DNA-dependent dimerization, subcellular partitioning and protein destabilization control WUSCHEL protein levels and spatial accumulation. Moreover, the destabilization of WUSCHEL may also depend on the protein concentration. However, the roles of extrinsic spatial cues in maintaining differential accumulation of WUS are not understood. Through transient manipulation of hormone levels, hormone response patterns and analysis of the receptor mutants, we show that cytokinin signaling in the rib meristem acts through the transcriptional regulatory domains, the acidic domain and the WUSCHEL-box, to stabilize the WUS protein. Furthermore, we show that the same WUSCHEL-box functions as a degron sequence in cytokinin deficient regions in the central zone, leading to the destabilization of WUSCHEL. The coupled functions of the WUSCHEL-box in nuclear retention as described earlier, together with cytokinin sensing, reinforce higher nuclear accumulation of WUSCHEL in the rib meristem. In contrast a sub-threshold level may expose the WUSCHEL-box to destabilizing signals in the central zone. Thus, the cytokinin signaling acts as an asymmetric spatial cue in stabilizing the WUSCHEL protein to lead to its differential accumulation in neighboring cells, which is critical for concentration-dependent spatial regulation of CLAVATA3 transcription and meristem maintenance. Furthermore, our work shows that

  11. Nuclear Energy Policy

    DTIC Science & Technology

    2007-07-12

    Nuclear Waste Storage Act of 2007. Requires commercial nuclear power plants to transfer spent fuel from pools to dry storage ...enrichment, spent fuel recycling (also called reprocessing), and other fuel cycle facilities that could be used to produce nuclear weapons materials...that had used the leased fuel , along with supplies of fresh nuclear fuel , according to the GNEP concept; see [http://www.gnep.energy.gov].

  12. Nuclear regulatory legislation: 102d Congress. Volume 1, No. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-10-01

    This document is a compilation of nuclear regulatory legislation and other relevant material through the 102d Congress, 2d Session. This compilation has been prepared for use as a resource document, which the NRC intends to update at the end of every Congress. The contents of NUREG-0980 include: The Atomic Energy Act of 1954, as amended; Energy Reorganization Act of 1974, as amended, Uranium Mill Tailings Radiation Control Act of 1978; Low-Level Radioactive Waste Policy Act; Nuclear Waste Policy Act of 1982; and NRC Authorization and Appropriations Acts. Other materials included are statutes and treaties on export licensing, nuclear non-proliferation, andmore » environmental protection.« less

  13. Nuclear regulatory legislation, 102d Congress. Volume 2, No. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-10-01

    This document is a compilation of nuclear regulatory legislation and other relevant material through the 102d Congress, 2d Session. This compilation has been prepared for use as a resource document, which the NRC intends to update at the end of every Congress. The contents of NUREG-0980 include The Atomic Energy Act of 1954, as amended; Energy Reorganization Act of 1974, as amended, Uranium Mill Tailings Radiation Control Act of 1978; Low-Level Radioactive Waste Policy Act; Nuclear Waste Policy Act of 1982; and NRC Authorization and Appropriations Acts. Other materials included are statutes and treaties on export licensing, nuclear non-proliferation, andmore » environmental protection.« less

  14. State regulation of nuclear power and national energy policy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moeller, J.W.

    1992-12-31

    In April 1983 and January 1984, the United States Supreme Court rendered two decisions that redefined the metes and bounds of federal preemption of commercial nuclear power plant regulation. In Pacific Gas & Electric Co. v. State Energy Resources Conservation and Development Commission (PG&E), the court decided that the Atomic Energy Act of 1954, as amended (the Act), did not preempt a California state law that established a moratorium on commercial nuclear power plant construction. In Silkwood v. Kerr-McGee Corporation, the Court also decided that the Act did not preempt a claim for damages under state tort law for radiologicalmore » injuries suffered in a nuclear fuel facility regulated by the United States Nuclear Regulatory Commission (NRC). The two decisions redefined the extent of federal preemption, under the Act and other federal law, of nuclear plant regulation as well as the extend of state regulation of nuclear plants. In the eight years since PG&E and Silkwood, numerous other developments have eroded further the breadth of federal preemption of commercial nuclear power plant regulation. This Article explores the developments, since PG&E and Silkwood, that have expanded further the scope of state and local regulation of commercial nuclear power plants. Specifically, the Article first identifies the extent of state and local participation in nuclear power regulation provided by the Act and other federal loan relevant to commercial nuclear power. Second, it discusses in detail the PG&E and Silkwood decisions. The Article also considers the impact of seven specific developments on the legislative implementation of a national energy policy that contemplates a role for nuclear power.« less

  15. 10 CFR 8.4 - Interpretation by the General Counsel: AEC jurisdiction over nuclear facilities and materials...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... over nuclear facilities and materials under the Atomic Energy Act. 8.4 Section 8.4 Energy NUCLEAR... nuclear facilities and materials under the Atomic Energy Act. (a) By virtue of the Atomic Energy Act of... Atomic Energy Act of 1954 sets out a pattern for licensing and regulation of certain nuclear materials...

  16. 10 CFR 8.4 - Interpretation by the General Counsel: AEC jurisdiction over nuclear facilities and materials...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... over nuclear facilities and materials under the Atomic Energy Act. 8.4 Section 8.4 Energy NUCLEAR... nuclear facilities and materials under the Atomic Energy Act. (a) By virtue of the Atomic Energy Act of... Atomic Energy Act of 1954 sets out a pattern for licensing and regulation of certain nuclear materials...

  17. 10 CFR 8.4 - Interpretation by the General Counsel: AEC jurisdiction over nuclear facilities and materials...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... over nuclear facilities and materials under the Atomic Energy Act. 8.4 Section 8.4 Energy NUCLEAR... nuclear facilities and materials under the Atomic Energy Act. (a) By virtue of the Atomic Energy Act of... Atomic Energy Act of 1954 sets out a pattern for licensing and regulation of certain nuclear materials...

  18. Defense Threat Reduction Agency > Home > DTRA No Fear Act Reporting

    Science.gov Websites

    FOIA Electronic Reading Room Privacy Impact Assessment DTRA No Fear Act Reporting Nuclear Test Personnel Review NTPR Fact Sheets NTPR Radiation Dose Assessment Documents US Atmospheric Nuclear Test History Documents US Underground Nuclear Test History Reports NTPR Radiation Exposure Reports Enewetak

  19. 78 FR 41835 - Inflation Adjustments to the Price-Anderson Act Financial Protection Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0... Price-Anderson Act Financial Protection Regulations AGENCY: Nuclear Regulatory Commission. ACTION: Final rule. SUMMARY: The Atomic Energy Act of 1954, as amended (AEA), requires the U.S. Nuclear Regulatory...

  20. Atmospheric effects and societal consequences of regional scale nuclear conflicts and acts of individual nuclear terrorism

    NASA Astrophysics Data System (ADS)

    Toon, O. B.; Turco, R. P.; Robock, A.; Bardeen, C.; Oman, L.; Stenchikov, G. L.

    2007-04-01

    We assess the potential damage and smoke production associated with the detonation of small nuclear weapons in modern megacities. While the number of nuclear warheads in the world has fallen by about a factor of three since its peak in 1986, the number of nuclear weapons states is increasing and the potential exists for numerous regional nuclear arms races. Eight countries are known to have nuclear weapons, 2 are constructing them, and an additional 32 nations already have the fissile material needed to build substantial arsenals of low-yield (Hiroshima-sized) explosives. Population and economic activity worldwide are congregated to an increasing extent in megacities, which might be targeted in a nuclear conflict. We find that low yield weapons, which new nuclear powers are likely to construct, can produce 100 times as many fatalities and 100 times as much smoke from fires per kt yield as previously estimated in analyses for full scale nuclear wars using high-yield weapons, if the small weapons are targeted at city centers. A single "small" nuclear detonation in an urban center could lead to more fatalities, in some cases by orders of magnitude, than have occurred in the major historical conflicts of many countries. We analyze the likely outcome of a regional nuclear exchange involving 100 15-kt explosions (less than 0.1% of the explosive yield of the current global nuclear arsenal). We find that such an exchange could produce direct fatalities comparable to all of those worldwide in World War II, or to those once estimated for a "counterforce" nuclear war between the superpowers. Megacities exposed to atmospheric fallout of long-lived radionuclides would likely be abandoned indefinitely, with severe national and international implications. Our analysis shows that smoke from urban firestorms in a regional war would rise into the upper troposphere due to pyro-convection. Robock et al. (2007) show that the smoke would subsequently rise deep into the stratosphere due

  1. Atmospheric effects and societal consequences of regional scale nuclear conflicts and acts of individual nuclear terrorism

    NASA Astrophysics Data System (ADS)

    Toon, O. B.; Turco, R. P.; Robock, A.; Bardeen, C.; Oman, L.; Stenchikov, G. L.

    2006-11-01

    We assess the potential damage and smoke production associated with the detonation of small nuclear weapons in modern megacities. While the number of nuclear warheads in the world has fallen by about a factor of three since its peak in 1986, the number of nuclear weapons states is increasing and the potential exists for numerous regional nuclear arms races. Eight countries are known to have nuclear weapons, 2 are constructing them, and an additional 32 nations already have the fissile material needed to build substantial arsenals of low-yield (Hiroshima-sized) explosives. Population and economic activity worldwide are congregated to an increasing extent in megacities, which might be targeted in a nuclear conflict. Our analysis shows that, per kiloton of yield, low yield weapons can produce 100 times as many fatalities and 100 times as much smoke from fires as high-yield weapons, if they are targeted at city centers. A single "small'' nuclear detonation in an urban center could lead to more fatalities, in some cases by orders of magnitude, than have occurred in the major historical conflicts of many countries. We analyze the likely outcome of a regional nuclear exchange involving 100 15-kt explosions (less than 0.1% of the explosive yield of the current global nuclear arsenal). We find that such an exchange could produce direct fatalities comparable to all of those worldwide in World War II, or to those once estimated for a "counterforce'' nuclear war between the superpowers. Megacities exposed to atmospheric fallout of long-lived radionuclides would likely be abandoned indefinitely, with severe national and international implications. Our analysis shows that smoke from urban firestorms in a regional war would rise into the upper troposphere due to pyro-convection. Robock et al. (2006) show that the smoke would subsequently rise deep into the stratosphere due to atmospheric heating, and then might induce significant climatic anomalies on global scales.We also

  2. 10 CFR 1304.112 - Notification of systems of Privacy Act records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Notification of systems of Privacy Act records. 1304.112 Section 1304.112 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.112 Notification of systems of Privacy Act records. (a) Public notice. On November 22, 1996, the Board published a...

  3. 10 CFR 1304.112 - Notification of systems of Privacy Act records.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Notification of systems of Privacy Act records. 1304.112 Section 1304.112 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.112 Notification of systems of Privacy Act records. (a) Public notice. On November 22, 1996, the Board published a...

  4. 10 CFR 1304.112 - Notification of systems of Privacy Act records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Notification of systems of Privacy Act records. 1304.112 Section 1304.112 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.112 Notification of systems of Privacy Act records. (a) Public notice. On November 22, 1996, the Board published a...

  5. 10 CFR 1304.112 - Notification of systems of Privacy Act records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Notification of systems of Privacy Act records. 1304.112 Section 1304.112 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.112 Notification of systems of Privacy Act records. (a) Public notice. On November 22, 1996, the Board published a...

  6. 10 CFR 1304.112 - Notification of systems of Privacy Act records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Notification of systems of Privacy Act records. 1304.112 Section 1304.112 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.112 Notification of systems of Privacy Act records. (a) Public notice. On November 22, 1996, the Board published a...

  7. 12 CFR 7.2014 - Indemnification of institution-affiliated parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., or the relevant provisions of the Model Business Corporation Act (1984, as amended 1994, and as... parties. (a) Administrative proceedings or civil actions initiated by Federal banking agencies. A national... agency, a national bank may indemnify an institution-affiliated party for damages and expenses, including...

  8. 10 CFR 1304.104 - Privacy Act records maintained by the Board.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Privacy Act records maintained by the Board. 1304.104 Section 1304.104 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.104 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an individual as...

  9. 10 CFR 1304.104 - Privacy Act records maintained by the Board.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Privacy Act records maintained by the Board. 1304.104 Section 1304.104 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.104 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an individual as...

  10. 10 CFR 1304.104 - Privacy Act records maintained by the Board.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Privacy Act records maintained by the Board. 1304.104 Section 1304.104 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.104 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an individual as...

  11. 10 CFR 1304.104 - Privacy Act records maintained by the Board.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Privacy Act records maintained by the Board. 1304.104 Section 1304.104 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.104 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an individual as...

  12. 10 CFR 1304.104 - Privacy Act records maintained by the Board.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Privacy Act records maintained by the Board. 1304.104 Section 1304.104 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.104 Privacy Act records maintained by the Board. (a) The Board shall maintain only such information about an individual as...

  13. 77 FR 67809 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). Federal Advisory Committee Act requires that public notice of these...

  14. Renewable and Nuclear Energy: an International Study of Students' Beliefs About, and Willingness to Act, in Relation to Two Energy Production Scenarios

    NASA Astrophysics Data System (ADS)

    Skamp, Keith; Boyes, Eddie; Stanisstreet, Martin; Rodriguez, Manuel; Malandrakis, Georgios; Fortner, Rosanne; Kilinc, Ahmet; Taylor, Neil; Chhokar, Kiran; Dua, Shweta; Ambusaidi, Abdullah; Cheong, Irene; Kim, Mijung; Yoon, Hye-Gyoung

    2017-07-01

    Renewable and nuclear energy are two plausible alternatives to fossil fuel-based energy production. This study reports students' beliefs about the usefulness of these two options in reducing global warming and their willingness to undertake actions that would encourage their uptake. Using a specially designed questionnaire, students' (n > 12,000; grades 6 to 10) responses were obtained from 11 countries. Links between their beliefs about these energy options and their willingness to act were quantified using a range of novel derived indices: significant differences between beliefs and willingness to act were found across the various counties. One derived index, the Potential Effectiveness of Education, measures the extent to which enhancing a person's belief in the effectiveness of an action might increase their willingness to undertake that action: this indicated that education may impact willingness to act in some countries more than others. Interpretations are proffered for the reported differences between countries including whether the extent of students' concern about global warming had impacted their decisions and whether cultural attributes had any influence. Pedagogical ways forward are related to the findings.

  15. Interactions of trans-acting factor(s) with the estradiol response element and nuclear factor 1 of the vitellogenin II gene of Japanese quail.

    PubMed

    Gupta, S; Upadhayay, R; Kanungo, M S

    1996-08-01

    This study was directed at achieving an understanding of the mechanisms by which steroid hormones control the synthesis of vitellogenin (VTG) protein in the liver of the Japanese quail. Northern hybridization shows that administration of estradiol alone or with progesterone stimulates the synthesis of VTG mRNA. Gel mobility shift assay of DNA fragments containing the ERE and NF 1 shows that estradiol alone or with progesterone increases the levels of nuclear proteins that bind to these cis-acting elements of the promoter of the VTG gene. The cooperative effect of the two hormones seen at the level of expression of the VTG gene may be due to protein-protein interactions of trans-acting factors that bind to ERE and NF 1.

  16. 75 FR 67351 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Office of Nuclear Energy, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770...

  17. 78 FR 29125 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Office of Nuclear Energy, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). Federal Advisory Committee Act (Pub. L. 94-463, 86 Stat. 770) requires...

  18. 76 FR 67717 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770...

  19. 75 FR 13269 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat. 770...

  20. 77 FR 26274 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). The Federal Advisory Committee Act (Pub. Law 92-463, 86 Stat. 770...

  1. 78 FR 70932 - Nuclear Energy Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... DEPARTMENT OF ENERGY Nuclear Energy Advisory Committee AGENCY: Office of Nuclear Energy, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Nuclear Energy Advisory Committee (NEAC). The Federal Advisory Committee Act (Public Law No. 94-463, 86 Stat. 770...

  2. The America COMPETES Act and the FY2009 Budget

    DTIC Science & Technology

    2008-10-17

    Junior Investigator, Nuclear Physics Outstanding Junior Investigator, Fusion Energy Sciences Plasma Physics Junior Faculty Development; Advanced...Instrumentation Fellowships, and the Fusion Energy Sciences Graduate Fellowships.20 The DOE Summer Institutes authorization in the act is $20 million in FY2009...corresponds to pre-existing High Energy Physics Outstanding Junior Investigator, Nuclear Physics Outstanding Junior Investigator, Fusion Energy Sciences Plasma

  3. 48 CFR 1850.104-70 - Lead NASA installation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Lead NASA installation... Actions 1850.104-70 Lead NASA installation. (a) Contractors applying for indemnification shall determine which NASA installation has the highest dollar amount of contracts for which indemnification is...

  4. 48 CFR 1850.104-70 - Lead NASA installation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Lead NASA installation... Actions 1850.104-70 Lead NASA installation. (a) Contractors applying for indemnification shall determine which NASA installation has the highest dollar amount of contracts for which indemnification is...

  5. 48 CFR 1850.104-70 - Lead NASA installation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Lead NASA installation... Actions 1850.104-70 Lead NASA installation. (a) Contractors applying for indemnification shall determine which NASA installation has the highest dollar amount of contracts for which indemnification is...

  6. 76 FR 19774 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... FEDERAL MARITIME COMMISSION Sunshine Act Meeting AGENCY HOLDING THE MEETING: Federal Maritime Commission. TIME AND DATE: April 13, 2011--10 a.m. PLACE: 800 North Capitol Street, NW., First Floor Hearing... on Situation at the Fukushima Nuclear Power Plant in Japan. 2. Staff Review and Recommendation...

  7. Psychomotor developmental delay and epilepsy in an offspring of father-daughter incest: quantification of the causality probability.

    PubMed

    Schmidtke, Jörg; Krawczak, Michael

    2010-09-01

    A 20-year-old offspring of father-daughter incest, who has been suffering from serious psychomotoric health problems since early childhood, is seeking financial compensation under the German federal act of victim indemnification. For her appeal to be valid, the probability X that the incest was causal for her disorder must exceed 50%. Based upon the available medical records, we show that this is indeed the case and that X is even likely to exceed 65%, thereby rendering the victim's claim scientifically and legally justified.

  8. 75 FR 28075 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0002] Sunshine Act Notice DATES: Weeks of May 17, 24, 31, June, 7, 14, 21, 2010. PLACE: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland..., 2010. Week of May 24, 2010--Tentative Thursday, May 27, 2010 9:30 a.m. Briefing on the Results of the...

  9. 75 FR 44072 - Export and Import of Nuclear Equipment and Material; Updates and Clarifications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... Energy Act. Retransfers of special nuclear material produced through the use of U.S.-obligated material... the Atomic Energy Act that apply to imports of special nuclear, source or byproduct material are... NUCLEAR REGULATORY COMMISSION 10 CFR Part 110 [NRC-2008-0567] RIN 3150-AI16 Export and Import of...

  10. Nuclear energy center site survey reactor plant considerations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harty, H.

    The Energy Reorganization Act of 1974 required the Nuclear Regulatory Commission (NRC) to make a nuclear energy center site survey (NECSS). Background information for the NECSS report was developed in a series of tasks which include: socioeconomic inpacts; environmental impact (reactor facilities); emergency response capability (reactor facilities); aging of nuclear energy centers; and dry cooled nuclear energy centers.

  11. Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor α Activation.

    PubMed

    Benoit, Thibaut; Valera, Marie-Cecile; Fontaine, Coralie; Buscato, Melissa; Lenfant, Francoise; Raymond-Letron, Isabelle; Tremollieres, Florence; Soulie, Michel; Foidart, Jean-Michel; Game, Xavier; Arnal, Jean-Francois

    2017-11-01

    The genitourinary syndrome of menopause has a negative impact on quality of life of postmenopausal women. The treatment of vulvovaginal atrophy includes administration of estrogens. However, oral estrogen treatment is controversial because of its potential risks on venous thrombosis and breast cancer. Estetrol (E4) is a natural estrogen synthesized exclusively during pregnancy by the human fetal liver and initially considered as a weak estrogen. However, E4 was recently evaluated in phase 1 to 2 clinical studies and found to act as an oral contraceptive in combination with a progestin, without increasing the level of coagulation factors. We recently showed that E4 stimulates uterine epithelial proliferation through nuclear estrogen receptor (ER) α, but failed to elicit endothelial responses. Herein, we first evaluated the morphological and functional impacts of E4 on the vagina of ovariectomized mice, and we determined the molecular mechanism mediating these effects. Vaginal epithelial proliferation and lubrication after stimulation were found to increase after E4 chronic treatment. Using a combination of pharmacological and genetic approaches, we demonstrated that these E4 effects on the vagina are mediated by nuclear ERα activation. Altogether, we demonstrate that the selective activation of nuclear ERα is both necessary and sufficient to elicit functional and structural effects on the vagina, and therefore E4 appears promising as a therapeutic option to improve vulvovaginal atrophy. Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  12. 22 CFR 123.20 - Nuclear related controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Nuclear related controls. 123.20 Section 123.20... DEFENSE ARTICLES § 123.20 Nuclear related controls. (a) The provisions of this subchapter do not apply to... of Energy or the Nuclear Regulatory Commission pursuant to the Atomic Energy Act of 1954, as amended...

  13. 22 CFR 123.20 - Nuclear related controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Nuclear related controls. 123.20 Section 123.20... DEFENSE ARTICLES § 123.20 Nuclear related controls. (a) The provisions of this subchapter do not apply to... of Energy or the Nuclear Regulatory Commission pursuant to the Atomic Energy Act of 1954, as amended...

  14. 22 CFR 123.20 - Nuclear related controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Nuclear related controls. 123.20 Section 123.20... DEFENSE ARTICLES § 123.20 Nuclear related controls. (a) The provisions of this subchapter do not apply to... of Energy or the Nuclear Regulatory Commission pursuant to the Atomic Energy Act of 1954, as amended...

  15. 22 CFR 123.20 - Nuclear related controls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Nuclear related controls. 123.20 Section 123.20... DEFENSE ARTICLES § 123.20 Nuclear related controls. (a) The provisions of this subchapter do not apply to... of Energy or the Nuclear Regulatory Commission pursuant to the Atomic Energy Act of 1954, as amended...

  16. 32 CFR Appendix A to Part 291 - Freedom of Information Act Request (DNA Form 524)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Freedom of Information Act Request (DNA Form 524... OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE NUCLEAR AGENCY (DNA) FREEDOM OF INFORMATION ACT PROGRAM Pt. 291, App. A Appendix A to Part 291—Freedom of Information Act Request (DNA Form...

  17. 32 CFR Appendix A to Part 291 - Freedom of Information Act Request (DNA Form 524)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Freedom of Information Act Request (DNA Form 524... OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE NUCLEAR AGENCY (DNA) FREEDOM OF INFORMATION ACT PROGRAM Pt. 291, App. A Appendix A to Part 291—Freedom of Information Act Request (DNA Form...

  18. 32 CFR Appendix A to Part 291 - Freedom of Information Act Request (DNA Form 524)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Freedom of Information Act Request (DNA Form 524... OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE NUCLEAR AGENCY (DNA) FREEDOM OF INFORMATION ACT PROGRAM Pt. 291, App. A Appendix A to Part 291—Freedom of Information Act Request (DNA Form...

  19. 32 CFR Appendix A to Part 291 - Freedom of Information Act Request (DNA Form 524)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Freedom of Information Act Request (DNA Form 524... OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE NUCLEAR AGENCY (DNA) FREEDOM OF INFORMATION ACT PROGRAM Pt. 291, App. A Appendix A to Part 291—Freedom of Information Act Request (DNA Form...

  20. 32 CFR Appendix A to Part 291 - Freedom of Information Act Request (DNA Form 524)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Freedom of Information Act Request (DNA Form 524... OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE NUCLEAR AGENCY (DNA) FREEDOM OF INFORMATION ACT PROGRAM Pt. 291, App. A Appendix A to Part 291—Freedom of Information Act Request (DNA Form...

  1. 77 FR 51791 - DOE/NSF Nuclear Science Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... DEPARTMENT OF ENERGY DOE/NSF Nuclear Science Advisory Committee AGENCY: Department of Energy.../NSF Nuclear Science Advisory Committee (NSAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86... on scientific priorities within the field of basic nuclear science research. Tentative Agenda: Agenda...

  2. 75 FR 6651 - DOE/NSF Nuclear Science Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... DEPARTMENT OF ENERGY DOE/NSF Nuclear Science Advisory Committee AGENCY: Department of Energy.../NSF Nuclear Science Advisory Committee (NSAC). Federal Advisory Committee Act (Pub. L. 92- 463, 86... on scientific priorities within the field of basic nuclear science research. Tentative Agenda: Agenda...

  3. 15 CFR 742.3 - Nuclear nonproliferation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

  4. 15 CFR 742.3 - Nuclear nonproliferation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

  5. 15 CFR 742.3 - Nuclear nonproliferation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

  6. 15 CFR 742.3 - Nuclear nonproliferation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

  7. 15 CFR 742.3 - Nuclear nonproliferation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.3 Nuclear nonproliferation. (a) License requirements. Section 309(c) of the Nuclear Non-Proliferation Act of 1978 requires BIS to identify items subject to the EAR that could be of...

  8. The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPAR{gamma}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Gwang Sik; Lee, Gha Young; Nedumaran, Balachandar

    2008-05-30

    DAX-1 is an atypical nuclear receptor (NR) which functions primarily as a transcriptional corepressor of other NRs via heterodimerization. Peroxisome proliferator-activated receptor (PPAR) {gamma} is a ligand-dependent NR which performs a key function in adipogenesis. In this study, we evaluated a novel cross-talk mechanism between DAX-1 and PPAR{gamma}. Transient transfection assays demonstrated that DAX-1 inhibits the transactivity of PPAR{gamma} in a dose-dependent manner. DAX-1 directly competed with the PPAR{gamma} coactivator (PGC)-1{alpha} for binding to PPAR{gamma}. Endogenous levels of DAX-1 were significantly lower in differentiated 3T3-L1 adipocytes as compared to preadipocytes. Using a retroviral expression system, we demonstrated that DAX-1 overexpressionmore » downregulates the expression of PPAR{gamma} target genes, resulting in an attenuation of adipogenesis in 3T3-L1 cells. Our results suggest that DAX-1 acts as a corepressor of PPAR{gamma} and performs a potential function in the regulation of PPAR{gamma}-mediated cellular differentiation.« less

  9. 78 FR 68868 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0001] Sunshine Act Meeting Notice DATES: Week of November... Management and Personnel Issues (Closed--Ex. 2 and 6) * * * * * *The schedule for Commission meetings is subject to change on short notice. To verify the status of meetings, call (recording)--301-415- 1292...

  10. 78 FR 70598 - Sunshine Act Meetings Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0001] Sunshine Act Meetings Notice DATES: Weeks of..., Rockville, Maryland. STATUS: Public and Closed. Week of November 25, 2013 There are no meetings scheduled for the week of November 25, 2013. Week of December 2, 2013--Tentative There are no meetings scheduled...

  11. 76 FR 31945 - DOE/NSF Nuclear Science Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... DEPARTMENT OF ENERGY DOE/NSF Nuclear Science Advisory Committee AGENCY: Department of Energy.../NSF Nuclear Science Advisory Committee (NSAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86... the field of basic nuclear science research. Tentative Agenda: Agenda will include discussions of the...

  12. 78 FR 12044 - DOE/NSF Nuclear Science Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... DEPARTMENT OF ENERGY DOE/NSF Nuclear Science Advisory Committee AGENCY: Office of Science... Nuclear Science Advisory Committee (NSAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat... Energy and the National Science Foundation on scientific priorities within the field of basic nuclear...

  13. 78 FR 72931 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0001] Sunshine Act Meeting Notice DATES: Weeks of December..., Rockville, Maryland. STATUS: Public and Closed. Week of December 2, 2013 There are no meetings scheduled for the week of December 2, 2013. Week of December 9, 2013--Tentative There are no meetings scheduled for...

  14. 78 FR 79021 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0001] Sunshine Act Meeting Notice DATES: Weeks of December... meetings scheduled for the week of December 30, 2013. Week of January 6, 2014--Tentative Monday, January 6... to Dry Casks (Public Meeting) (Contact: Kevin Witt, 301-415-2145). This meeting will be webcast live...

  15. 78 FR 67344 - Sunshine Act Meeting; New Time and Date of Proceeding

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Meeting; New Time and Date of Proceeding AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Notice of Public Meeting and Hearing; New Time... the postponement in the Federal Register due to the shutdown. The Board has now decided on a new time...

  16. History of nuclear technology development in Japan

    NASA Astrophysics Data System (ADS)

    Yamashita, Kiyonobu

    2015-04-01

    Nuclear technology development in Japan has been carried out based on the Atomic Energy Basic Act brought into effect in 1955. The nuclear technology development is limited to peaceful purposes and made in a principle to assure their safety. Now, the technologies for research reactors radiation application and nuclear power plants are delivered to developing countries. First of all, safety measures of nuclear power plants (NPPs) will be enhanced based on lesson learned from TEPCO Fukushima Daiichi NPS accident.

  17. History of nuclear technology development in Japan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yamashita, Kiyonobu, E-mail: yamashita.kiyonobu@jaea.go.jp; General Advisor Nuclear HRD Centre, Japan Atomic Energy Agency, TOKAI-mura, NAKA-gun, IBARAKI-ken, 319-1195

    2015-04-29

    Nuclear technology development in Japan has been carried out based on the Atomic Energy Basic Act brought into effect in 1955. The nuclear technology development is limited to peaceful purposes and made in a principle to assure their safety. Now, the technologies for research reactors radiation application and nuclear power plants are delivered to developing countries. First of all, safety measures of nuclear power plants (NPPs) will be enhanced based on lesson learned from TEPCO Fukushima Daiichi NPS accident.

  18. 78 FR 69462 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0001] Sunshine Act Meeting Notice DATE: Weeks of November...--Tentative There are no meetings scheduled for the week of November 25, 2013. Week of December 2, 2013--Tentative There are no meetings scheduled for the week of December 2, 2013. Week of December 9, 2013...

  19. Dissipatively Stabilized Quantum Sensor Based on Indirect Nuclear-Nuclear Interactions

    NASA Astrophysics Data System (ADS)

    Chen, Q.; Schwarz, I.; Plenio, M. B.

    2017-07-01

    We propose to use a dissipatively stabilized nitrogen vacancy (NV) center as a mediator of interaction between two nuclear spins that are protected from decoherence and relaxation of the NV due to the periodical resets of the NV center. Under ambient conditions this scheme achieves highly selective high-fidelity quantum gates between nuclear spins in a quantum register even at large NV-nuclear distances. Importantly, this method allows for the use of nuclear spins as a sensor rather than a memory, while the NV spin acts as an ancillary system for the initialization and readout of the sensor. The immunity to the decoherence and relaxation of the NV center leads to a tunable sharp frequency filter while allowing at the same time the continuous collection of the signal to achieve simultaneously high spectral selectivity and high signal-to-noise ratio.

  20. DoD Nuclear Weapons Personnel Reliability Assurance

    DTIC Science & Technology

    2016-04-27

    destructive power, and the potential consequences of an accident or unauthorized act. Assured nuclear weapons safety, security, and control remain of...DOD INSTRUCTION 5210.42 DOD NUCLEAR WEAPONS PERSONNEL RELIABILITY ASSURANCE Originating Component: Office of the Under Secretary of...from the DoD Issuances Website at http://www.dtic.mil/whs/directives. Reissues and renames: DoD Instruction 5210.42, “ Nuclear Weapons Personnel

  1. 3 CFR - Certifications Pursuant to Section 104 of the United States-India Nuclear Cooperation Approval...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act Regarding the Safeguards Agreement Between India and the International Atomic Energy Agency Presidential Documents Other Presidential... of the United States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act...

  2. Nuclear Forensics: A Methodology Applicable to Nuclear Security and to Non-Proliferation

    NASA Astrophysics Data System (ADS)

    Mayer, K.; Wallenius, M.; Lützenkirchen, K.; Galy, J.; Varga, Z.; Erdmann, N.; Buda, R.; Kratz, J.-V.; Trautmann, N.; Fifield, K.

    2011-09-01

    Nuclear Security aims at the prevention and detection of and response to, theft, sabotage, unauthorized access, illegal transfer or other malicious acts involving nuclear material. Nuclear Forensics is a key element of nuclear security. Nuclear Forensics is defined as a methodology that aims at re-establishing the history of nuclear material of unknown origin. It is based on indicators that arise from known relationships between material characteristics and process history. Thus, nuclear forensics analysis includes the characterization of the material and correlation with production history. To this end, we can make use of parameters such as the isotopic composition of the nuclear material and accompanying elements, chemical impurities, macroscopic appearance and microstructure of the material. In the present paper, we discuss the opportunities for attribution of nuclear material offered by nuclear forensics as well as its limitations. Particular attention will be given to the role of nuclear reactions. Such reactions include the radioactive decay of the nuclear material, but also reactions with neutrons. When uranium (of natural composition) is exposed to neutrons, plutonium is formed, as well as 236U. We will illustrate the methodology using the example of a piece of uranium metal that dates back to the German nuclear program in the 1940's. A combination of different analytical techniques and model calculations enables a nuclear forensics interpretation, thus correlating the material characteristics with the production history.

  3. Malaysian public perception towards nuclear power energy-related issues

    NASA Astrophysics Data System (ADS)

    Misnon, Fauzan Amin; Hu, Yeoh Siong; Rahman, Irman Abd.; Yasir, Muhamad Samudi

    2017-01-01

    Malaysia had considered nuclear energy as an option for future electricity generation during the 9th Malaysia Development Plan. Since 2009, Malaysia had implemented a number of important preparatory steps towards this goal, including the establishment of Nuclear Power Corporation of Malaysia (MNPC) as first Nuclear Energy Programme Implementing Organization (NEPIO) in Malaysia. In light of the establishment of MNPC, the National Nuclear Policy was formulated in 2010 and a new comprehensive nuclear law to replace the existing Atomic Energy Licensing Act (Act 304) is currently in the pipeline. Internationally, public acceptance is generally used to gauge the acceptance of nuclear energy by the public whenever a government decides to engage in nuclear energy. A public survey was conducted in between 14 March 2016 to 10 May 2016 focusing on the Malaysian public acceptance and perception towards the implementation of nuclear energy in Malaysia. The methodology of this research was aim on finding an overview of the general knowledge, public-relation recommendation, perception and acceptance of Malaysian towards the nuclear power development program. The combination of information gathered from this study can be interpreted as an indication of the complexity surrounding the development of nuclear energy and its relationship with the unique background of Malaysian demography. This paper will focus mainly on energy-related section in the survey in comparison with nuclear energy.

  4. Occupational exposure assessment: Practices in Malaysian nuclear agency

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarowi, S. Muhd, E-mail: suzie@nuclearmalaysia.gov.my; Ramli, S. A.; Kontol, K. Mohamad

    Malaysian Nuclear Agency (Nuclear Malaysia) is the leading agency in introducing and promoting the application of nuclear science technology in Malaysia. The agency provides major nuclear facilities purposely for research and commercialisation such as reactor, irradiation plants and radioisotope production laboratory. When dealing with ionizing radiation, there is an obligatory requirement to monitor and assess the radiation exposure to the workers. The personal dose of radiation workers were monitored monthly by assessing their Thermoluminescence Dosimeter (TLD) dose reading. This paper will discuss the current practice in managing, assessing, record keeping and reporting of the occupational exposure in Nuclear Malaysia includingmore » the Health Physic Group roles and challenges. The statistics on occupational radiation exposure of monitored workers working in different fields in Nuclear Malaysia from 2011 - 2013 will also be presented. The results show that the null hypothesis (H{sub 0}) was accepted which the means of every populations are all equal or not differ significantly. This hypothesis states that the dose exposure received by the radiation workers in Nuclear Malaysia is similar and there were no significant changes from 2011 to 2013. The radiation monitoring programme correlate with the requirement of our national law, the Atomic Energy Licensing Act 1984 (Act 304)« less

  5. Occupational exposure assessment: Practices in Malaysian nuclear agency

    NASA Astrophysics Data System (ADS)

    Sarowi, S. Muhd; Ramli, S. A.; Kontol, K. Mohamad; Rahman, N. A. H. Abd.

    2016-01-01

    Malaysian Nuclear Agency (Nuclear Malaysia) is the leading agency in introducing and promoting the application of nuclear science technology in Malaysia. The agency provides major nuclear facilities purposely for research and commercialisation such as reactor, irradiation plants and radioisotope production laboratory. When dealing with ionizing radiation, there is an obligatory requirement to monitor and assess the radiation exposure to the workers. The personal dose of radiation workers were monitored monthly by assessing their Thermoluminescence Dosimeter (TLD) dose reading. This paper will discuss the current practice in managing, assessing, record keeping and reporting of the occupational exposure in Nuclear Malaysia including the Health Physic Group roles and challenges. The statistics on occupational radiation exposure of monitored workers working in different fields in Nuclear Malaysia from 2011 - 2013 will also be presented. The results show that the null hypothesis (H₀) was accepted which the means of every populations are all equal or not differ significantly. This hypothesis states that the dose exposure received by the radiation workers in Nuclear Malaysia is similar and there were no significant changes from 2011 to 2013. The radiation monitoring programme correlate with the requirement of our national law, the Atomic Energy Licensing Act 1984 (Act 304).

  6. Nuclear and radiological Security: Introduction.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, James Christopher

    Nuclear security includes the prevention and detection of, and response to, theft, sabotage, unauthorized access, illegal transfer, or other malicious acts involving nuclear or other radioactive substances or their associated facilities. The presentation begins by discussing the concept and its importance, then moves on to consider threats--insider threat, sabotage, diversion of materials--with considerable emphasis on the former. The intrusion at Pelindaba, South Africa, is described as a case study. The distinction between nuclear security and security of radiological and portable sources is clarified, and the international legal framework is touched upon. The paper concludes by discussing the responsibilities of themore » various entities involved in nuclear security.« less

  7. Report to Congress on the Indemnification of Contractors Performing Environmental Restoration

    DTIC Science & Technology

    1993-11-01

    munitions dating from World War I. This led true if the contractor is uninsured or has inadequate to the discovery that this residential area had once...application of this authority to the Pab. L. 8545 , 𔄁he National Defemse Contracts Act" specific circumstances of an environmental restoration I contracting

  8. 10 CFR Appendix C to Part 73 - Nuclear Power Plant Safeguards Contingency Plans

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Nuclear Power Plant Safeguards Contingency Plans C Appendix C to Part 73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND... sabotage relating to special nuclear material or nuclear facilities licensed under the Atomic Energy Act of...

  9. 10 CFR Appendix C to Part 73 - Nuclear Power Plant Safeguards Contingency Plans

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Nuclear Power Plant Safeguards Contingency Plans C Appendix C to Part 73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND... sabotage relating to special nuclear material or nuclear facilities licensed under the Atomic Energy Act of...

  10. Catholic doctrine and nuclear dogmatics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paradise, S.I.

    The bishops' pastoral letter challenging US nuclear strategy is based on the moral doctrine of a just war and post-World War II anti-Communist developments within the church. They advocate non-violence and active pursuit of peace, but retain the just war theory. They interpret nuclear deterrence as morally flawed and a driving force in the arms race, but they offer a moral loophole by advocating only bilateral and verifiable disarmament. The controversy centers on how quickly Christians are obligated to act. 9 references. (DCK)

  11. Analysis of the transient response of nuclear spins in GaAs with/without nuclear magnetic resonance

    NASA Astrophysics Data System (ADS)

    Rasly, Mahmoud; Lin, Zhichao; Yamamoto, Masafumi; Uemura, Tetsuya

    2016-05-01

    As an alternative to studying the steady-state responses of nuclear spins in solid state systems, working within a transient-state framework can reveal interesting phenomena. The response of nuclear spins in GaAs to a changing magnetic field was analyzed based on the time evolution of nuclear spin temperature. Simulation results well reproduced our experimental results for the transient oblique Hanle signals observed in an all-electrical spin injection device. The analysis showed that the so called dynamic nuclear polarization can be treated as a cooling tool for the nuclear spins: It works as a provider to exchange spin angular momentum between polarized electron spins and nuclear spins through the hyperfine interaction, leading to an increase in the nuclear polarization. In addition, a time-delay of the nuclear spin temperature with a fast sweep of the external magnetic field produces a possible transient state for the nuclear spin polarization. On the other hand, the nuclear magnetic resonance acts as a heating tool for a nuclear spin system. This causes the nuclear spin temperature to jump to infinity: i.e., the average nuclear spins along with the nuclear field vanish at resonant fields of 75As, 69Ga and 71Ga, showing an interesting step-dip structure in the oblique Hanle signals. These analyses provide a quantitative understanding of nuclear spin dynamics in semiconductors for application in future computation processing.

  12. Nuclear Fabrication Consortium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levesque, Stephen

    2013-04-05

    This report summarizes the activities undertaken by EWI while under contract from the Department of Energy (DOE) Office of Nuclear Energy (NE) for the management and operation of the Nuclear Fabrication Consortium (NFC). The NFC was established by EWI to independently develop, evaluate, and deploy fabrication approaches and data that support the re-establishment of the U.S. nuclear industry: ensuring that the supply chain will be competitive on a global stage, enabling more cost-effective and reliable nuclear power in a carbon constrained environment. The NFC provided a forum for member original equipment manufactures (OEM), fabricators, manufacturers, and materials suppliers to effectivelymore » engage with each other and rebuild the capacity of this supply chain by : Identifying and removing impediments to the implementation of new construction and fabrication techniques and approaches for nuclear equipment, including system components and nuclear plants. Providing and facilitating detailed scientific-based studies on new approaches and technologies that will have positive impacts on the cost of building of nuclear plants. Analyzing and disseminating information about future nuclear fabrication technologies and how they could impact the North American and the International Nuclear Marketplace. Facilitating dialog and initiate alignment among fabricators, owners, trade associations, and government agencies. Supporting industry in helping to create a larger qualified nuclear supplier network. Acting as an unbiased technology resource to evaluate, develop, and demonstrate new manufacturing technologies. Creating welder and inspector training programs to help enable the necessary workforce for the upcoming construction work. Serving as a focal point for technology, policy, and politically interested parties to share ideas and concepts associated with fabrication across the nuclear industry. The report the objectives and summaries of the Nuclear Fabrication

  13. 77 FR 27113 - Export and Import of Nuclear Equipment and Material; Export of International Atomic Energy Agency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-09

    ... relations, Nuclear materials, Nuclear power plants and reactors, Reporting and recordkeeping requirements... Reorganization Act sec. 201 (42 U.S.C. 5841; Solar, Wind, Waste, and Geothermal Power Act of 1990 sec. 5 (42 U.S... security of the United States. Because this rule involves a foreign affairs function of the United States...

  14. Security culture for nuclear facilities

    NASA Astrophysics Data System (ADS)

    Gupta, Deeksha; Bajramovic, Edita

    2017-01-01

    Natural radioactive elements are part of our environment and radioactivity is a natural phenomenon. There are numerous beneficial applications of radioactive elements (radioisotopes) and radiation, starting from power generation to usages in medical, industrial and agriculture applications. But the risk of radiation exposure is always attached to operational workers, the public and the environment. Hence, this risk has to be assessed and controlled. The main goal of safety and security measures is to protect human life, health, and the environment. Currently, nuclear security considerations became essential along with nuclear safety as nuclear facilities are facing rapidly increase in cybersecurity risks. Therefore, prevention and adequate protection of nuclear facilities from cyberattacks is the major task. Historically, nuclear safety is well defined by IAEA guidelines while nuclear security is just gradually being addressed by some new guidance, especially the IAEA Nuclear Security Series (NSS), IEC 62645 and some national regulations. At the overall level, IAEA NSS 7 describes nuclear security as deterrence and detection of, and response to, theft, sabotage, unauthorized access, illegal transfer or other malicious acts involving nuclear, other radioactive substances and their associated facilities. Nuclear security should be included throughout nuclear facilities. Proper implementation of a nuclear security culture leads to staff vigilance and a high level of security posture. Nuclear security also depends on policy makers, regulators, managers, individual employees and members of public. Therefore, proper education and security awareness are essential in keeping nuclear facilities safe and secure.

  15. The ACT Vision Mission Study Simulation Effort

    NASA Astrophysics Data System (ADS)

    Wunderer, C. B.; Kippen, R. M.; Bloser, P. F.; Boggs, S. E.; McConnell, M. L.; Hoover, A.; Oberlack, U.; Sturner, S.; Tournear, D.; Weidenspointner, G.; Zoglauer, A.

    2004-12-01

    The Advanced Compton Telescope (ACT) has been selected by NASA for a one-year "Vision Mission" study. The main goal of this study is to determine feasible instrument configurations to achieve ACT's sensitivity requirements, and to give recommendations for technology development. Space-based instruments operating in the energy range of nuclear lines are subject to complex backgrounds generated by cosmic-ray interactions and diffuse gamma rays; typically measurements are significantly background-dominated. Therefore accurate, detailed simulations of the background induced in different ACT configurations, and exploration of event selection and reconstruction techniques for reducing these backgrounds, are crucial to determining both the capabilities of a given instrument configuration and the technology enhancements that would result in the most significant performance improvements. The ACT Simulation team has assembled a complete suite of tools that allows the generation of particle backgrounds for a given orbit (based on CREME96), their propagation through any instrument and spacecraft geometry (using MGGPOD) - including delayed photon emission from instrument activation - as well as the event selection and reconstruction of Compton-scatter events in the given detectors (MEGAlib). The package can deal with polarized photon beams as well as e.g. anticoincidence shields. We will report on the progress of the ACT simulation effort and the suite of tools used. We thank Elena Novikova at NRL for her contributions, and NASA for support of this research.

  16. Financial protection against nuclear hazards: implications of the Supreme Court's decision in Silkwood

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rockett, L.R.

    1985-01-01

    The study evaluates the operation of the Price-Anderson Act in the light of 10 years of experience and the changes that have occurred during the period in the law and regulations and in the nuclear and insurance industries. It provides an independent analysis of various proposals to extend or amend the Act prior to its 1987 expiration. The five chapters deal with historical background and scope, financial protection under the Act, financial protection without the Act, legislative goals and issues, and alternative proposals. The report concludes that no scheme can fully satisfy all of the criteria, bu a careful balancingmore » will depend upon congressional decision on the extent to which federal policy should encourage continued participation by private industry in the nuclear field. Selected footnotes follow each chapter.« less

  17. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Attacks and destructive acts by enemies of the United States; and defense activities. 50.13 Section 50.13 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... the effects of (a) attacks and destructive acts, including sabotage, directed against the facility by...

  18. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Attacks and destructive acts by enemies of the United States; and defense activities. 50.13 Section 50.13 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... the effects of (a) attacks and destructive acts, including sabotage, directed against the facility by...

  19. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Attacks and destructive acts by enemies of the United States; and defense activities. 50.13 Section 50.13 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... the effects of (a) attacks and destructive acts, including sabotage, directed against the facility by...

  20. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Attacks and destructive acts by enemies of the United States; and defense activities. 50.13 Section 50.13 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... the effects of (a) attacks and destructive acts, including sabotage, directed against the facility by...

  1. Analysis of the transient response of nuclear spins in GaAs with/without nuclear magnetic resonance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rasly, Mahmoud; Lin, Zhichao; Yamamoto, Masafumi

    As an alternative to studying the steady-state responses of nuclear spins in solid state systems, working within a transient-state framework can reveal interesting phenomena. The response of nuclear spins in GaAs to a changing magnetic field was analyzed based on the time evolution of nuclear spin temperature. Simulation results well reproduced our experimental results for the transient oblique Hanle signals observed in an all-electrical spin injection device. The analysis showed that the so called dynamic nuclear polarization can be treated as a cooling tool for the nuclear spins: It works as a provider to exchange spin angular momentum between polarizedmore » electron spins and nuclear spins through the hyperfine interaction, leading to an increase in the nuclear polarization. In addition, a time-delay of the nuclear spin temperature with a fast sweep of the external magnetic field produces a possible transient state for the nuclear spin polarization. On the other hand, the nuclear magnetic resonance acts as a heating tool for a nuclear spin system. This causes the nuclear spin temperature to jump to infinity: i.e., the average nuclear spins along with the nuclear field vanish at resonant fields of {sup 75}As, {sup 69}Ga and {sup 71}Ga, showing an interesting step-dip structure in the oblique Hanle signals. These analyses provide a quantitative understanding of nuclear spin dynamics in semiconductors for application in future computation processing.« less

  2. Miniaturized nuclear battery

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adler, K.; Ducommun, G.

    1976-01-20

    The invention relates to a miniaturized nuclear battery, consisting of several in series connected cells, wherein each cell contains a support which acts as positive pole and which supports on one side a ..beta..-emitter, above said emitter is a radiation resisting insulation layer which is covered by an absorption layer, above which is a collector layer, and wherein the in series connected calls are disposed in an airtight case.

  3. Mediator-dependent Nuclear Receptor Functions

    PubMed Central

    Chen, Wei; Roeder, Robert

    2011-01-01

    As gene-specific transcription factors, nuclear hormone receptors are broadly involved in many important biological processes. Their function on target genes requires the stepwise assembly of different coactivator complexes that facilitate chromatin remodeling and subsequent preinitiation complex (PIC) formation and function. Mediator has proved to be a crucial, and general, nuclear receptor-interacting coactivator, with demonstrated functions in transcription steps ranging from chromatin remodeling to subsequent PIC formation and function. Here we discuss (i) our current understanding of pathways that nuclear receptors and other interacting cofactors employ to recruit Mediator to target gene enhancers and promoters, including conditional requirements for the strong NR-Mediator interactions mediated by the NR AF2 domain and the MED1 LXXLLL motifs and (ii) mechanisms by which Mediator acts to transmit signals from enhancer-bound nuclear receptors to the general transcription machinery at core promoters to effect PIC formation and function. PMID:21854863

  4. Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration

    PubMed Central

    Bernis, Cyril; Swift-Taylor, Beth; Nord, Matthew; Carmona, Sarah; Chook, Yuh Min; Forbes, Douglass J.

    2014-01-01

    The nuclear import receptors importin β and transportin play a different role in mitosis: both act phenotypically as spatial regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclusively around chromatin. Importin β is known to act by repressing assembly factors in regions distant from chromatin, whereas RanGTP produced on chromatin frees factors from importin β for localized assembly. The mechanism of transportin regulation was unknown. Diametrically opposed models for transportin action are as follows: 1) indirect action by RanGTP sequestration, thus down-regulating release of assembly factors from importin β, and 2) direct action by transportin binding and inhibiting assembly factors. Experiments in Xenopus assembly extracts with M9M, a superaffinity nuclear localization sequence that displaces cargoes bound by transportin, or TLB, a mutant transportin that can bind cargo and RanGTP simultaneously, support direct inhibition. Consistently, simple addition of M9M to mitotic cytosol induces microtubule aster assembly. ELYS and the nucleoporin 107–160 complex, components of mitotic kinetochores and nuclear pores, are blocked from binding to kinetochores in vitro by transportin, a block reversible by M9M. In vivo, 30% of M9M-transfected cells have spindle/cytokinesis defects. We conclude that the cell contains importin β and transportin “global positioning system”or “GPS” pathways that are mechanistically parallel. PMID:24478460

  5. 3 CFR - Delegation of Certain Functions Under Section 204(c) of the United States-India Nuclear...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) of the United States-India Nuclear Cooperation Approval and Nonproliferation Enhancement Act (Public... Delegation of Certain Functions Under Section 204(c) of the United States-India Nuclear Cooperation Approval... the President by section 204(c) of the United States-India Nuclear Cooperation Approval and...

  6. 76 FR 3678 - Board Meeting: February 16, 2011-Las Vegas, NV, the U.S. Nuclear Waste Technical Review Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: February 16, 2011--Las Vegas, NV, the U.S. Nuclear Waste Technical Review Board Will Meet To Discuss DOE Activities Related to Managing Spent Nuclear...-203, Nuclear Waste Policy Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will...

  7. Impact of the deployment schedule of fast breeding reactors in the frame of French act for nuclear materials and radioactive waste management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Le Mer, J.; Garzenne, C.; Lemasson, D.

    In the frame of the French Act of June 28, 2006 on 'a sustainable management of nuclear materials and radioactive waste' EDF R and D assesses various research scenarios of transition between the actual French fleet and a Generation IV fleet with a closed fuel cycle where plutonium is multi-recycled. The basic scenarios simulate a deployment of 60 GWe of Sodium-cooled Fast Reactors (SFRs) in two steps: one third from 2040 to 2050 and the rest from 2080 to 2100 (scenarios 2040). These research scenarios assume that SFR technology will be ready for industrial deployment in 2040. One of themore » many sensitivity analyses that EDF, as a nuclear power plant operator, must evaluate is the impact of a delay of SFR technology in terms of uranium consumptions, plutonium needs and fuel cycle utilities gauging. The sensitivity scenarios use the same assumptions as scenarios 2040 but they simulate a different transition phase: SFRs are deployed in one step between 2080 and 2110 (scenarios 2080). As the French Act states to conduct research on minor actinides (MA) management, we studied different options for 2040 and 2080 scenarios: no MA transmutation, americium transmutation in heterogeneous mode based on americium Bearing Blankets (AmBB) in SFRs and all MA transmutation in heterogeneous mode based on MA Bearing Blankets (MABB). Moreover, we studied multiple parameters that could impact the deployment of these reactors (SFR load factor, increase of the use of MOX in Light Water Reactors, increase of the cooling time in spent nuclear fuel storage...). Each scenario has been computed with the EDF R and D fuel cycle simulation code TIRELIRE-STRATEGIE and optimized to meet various fuel cycle constraints such as using the reprocessing facility with long period of constant capacity, keeping the temporary stored mass of plutonium and MA under imposed limits, recycling older assemblies first... These research scenarios show that the transition from the current PWR fleet to an

  8. Taking a stand against nuclear proliferation: the pediatrician's role.

    PubMed

    Newman, Thomas B

    2008-05-01

    Nuclear weapons pose a grave threat to the health of children. The Nuclear Nonproliferation Treaty, which for almost 40 years has limited the spread of nuclear weapons, is in danger of unraveling. At the 2000 Nuclear Nonproliferation Treaty Review Conference, 180 countries, including the United States, agreed on 13 practical steps to implement Article VI of the treaty, which calls for nuclear disarmament. However, the United States has acted in contravention of several of those disarmament steps, with announced plans to develop new nuclear weapons and to maintain a large nuclear arsenal for decades to come. Pediatricians, working individually and through organizations such as the American Academy of Pediatrics and International Physicians for the Prevention of Nuclear War, can educate the public and elected officials regarding the devastating and irremediable effects of nuclear weapons on children and the need for policies that comply with and strengthen the Nuclear Nonproliferation Treaty, rather than undermining it. For the children of the world, our goal must be a nuclear weapons convention (similar to the chemical and biological weapons conventions) that would prohibit these weapons globally.

  9. 76 FR 32994 - Nine Mile Point 3 Nuclear Project, LLC and Unistar Nuclear Operating Services, LLC; Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... December 1, 2009, UniStar Nuclear Energy (UNE), which is acting on behalf of the COL applicants Nine Mile... impacted by this exemption. Special Circumstances Special circumstances, in accordance with 10 CFR 50.12(a... exemption from 10 CFR 50.71(e)(3)(iii) exist. Eligibility for Categorical Exclusion From Environmental...

  10. Nuclear Terrorism: The Possibilities, Probable Consequences, and Preventive Strategies.

    ERIC Educational Resources Information Center

    Totten, Michael

    1986-01-01

    This article explores the possibility of terrorist acts against nuclear power stations. It includes information on reactor security, public policy, and alternative courses of action deemed to increase public safety and cost efficiency. (JDH)

  11. 77 FR 6131 - Memorandum of Understanding Between the U.S. Nuclear Regulatory Commission and the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    .... Background Nuclear Regulatory Commission Pursuant to Section 103 of the Atomic Energy Act of 1954, as amended... NUCLEAR REGULATORY COMMISSION DEPARTMENT OF HOMELAND SECURITY [NRC-2012-0015] Memorandum of Understanding Between the U.S. Nuclear Regulatory Commission and the Department of Homeland Security Regarding...

  12. Advertising the atom: federal promotion of nuclear power, 1953-1984

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, M.

    The public relations strategies of the Atomic Energy Commission (AEC) and the nuclear power industry reveal both public and official perceptions of nuclear power and the social uses of technology in general during the first 15 years after passage of the Atomic Energy Act of 1954. The relation between nuclear promotion and regulation also helps explain the environmental crisis of the 1969-1984 years. Project Plowshare coincides roughly with the early promotional years, and provides a case study of the relation of regulatory standards to promotion in AEC policymaking. The author examines the environmentalists challenge to nuclear power that emerged inmore » 1969 alongside government and industry response. He concludes with an assessment of the present state of federal nuclear power policy and of the nuclear power industry.« less

  13. 78 FR 4879 - Nine Mile Point 3 Nuclear Project, LLC and UniStar Nuclear Operating Services, LLC Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... Analysis Report (FSAR). On December 1, 2009, UniStar Nuclear Energy (UNE), acting on behalf of the COL... Exclusion From Environmental Review With respect to the exemption's impact on the quality of the human... relation to security issues. Therefore, the common defense and security is not impacted by this exemption...

  14. Distinct roles for key karyogamy proteins during yeast nuclear fusion.

    PubMed

    Melloy, Patricia; Shen, Shu; White, Erin; Rose, Mark D

    2009-09-01

    During yeast mating, cell fusion is followed by the congression and fusion of the two nuclei. Proteins required for nuclear fusion are found at the surface (Prm3p) and within the lumen (Kar2p, Kar5p, and Kar8p) of the nuclear envelope (NE). Electron tomography (ET) of zygotes revealed that mutations in these proteins block nuclear fusion with different morphologies, suggesting that they act in different steps of fusion. Specifically, prm3 zygotes were blocked before formation of membrane bridges, whereas kar2, kar5, and kar8 zygotes frequently contained them. Membrane bridges were significantly larger and occurred more frequently in kar2 and kar8, than in kar5 mutant zygotes. The kinetics of NE fusion in prm3, kar5, and kar8 mutants, measured by live-cell fluorescence microscopy, were well correlated with the size and frequency of bridges observed by ET. However the kar2 mutant was defective for transfer of NE lumenal GFP, but not diffusion within the lumen, suggesting that transfer was blocked at the NE fusion junction. These observations suggest that Prm3p acts before initiation of outer NE fusion, Kar5p may help dilation of the initial fusion pore, and Kar2p and Kar8p act after outer NE fusion, during inner NE fusion.

  15. An emerging link between LIM domain proteins and nuclear receptors.

    PubMed

    Sala, Stefano; Ampe, Christophe

    2018-06-01

    Nuclear receptors are ligand-activated transcription factors that partake in several biological processes including development, reproduction and metabolism. Over the last decade, evidence has accumulated that group 2, 3 and 4 LIM domain proteins, primarily known for their roles in actin cytoskeleton organization, also partake in gene transcription regulation. They shuttle between the cytoplasm and the nucleus, amongst other as a consequence of triggering cells with ligands of nuclear receptors. LIM domain proteins act as important coregulators of nuclear receptor-mediated gene transcription, in which they can either function as coactivators or corepressors. In establishing interactions with nuclear receptors, the LIM domains are important, yet pleiotropy of LIM domain proteins and nuclear receptors frequently occurs. LIM domain protein-nuclear receptor complexes function in diverse physiological processes. Their association is, however, often linked to diseases including cancer.

  16. The defective nuclear lamina in Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient and inhibits nuclear localization of Ubc9.

    PubMed

    Kelley, Joshua B; Datta, Sutirtha; Snow, Chelsi J; Chatterjee, Mandovi; Ni, Li; Spencer, Adam; Yang, Chun-Song; Cubeñas-Potts, Caelin; Matunis, Michael J; Paschal, Bryce M

    2011-08-01

    The mutant form of lamin A responsible for the premature aging disease Hutchinson-Gilford progeria syndrome (termed progerin) acts as a dominant negative protein that changes the structure of the nuclear lamina. How the perturbation of the nuclear lamina in progeria is transduced into cellular changes is undefined. Using patient fibroblasts and a variety of cell-based assays, we determined that progerin expression in Hutchinson-Gilford progeria syndrome inhibits the nucleocytoplasmic transport of several factors with key roles in nuclear function. We found that progerin reduces the nuclear/cytoplasmic concentration of the Ran GTPase and inhibits the nuclear localization of Ubc9, the sole E2 for SUMOylation, and of TPR, the nucleoporin that forms the basket on the nuclear side of the nuclear pore complex. Forcing the nuclear localization of Ubc9 in progerin-expressing cells rescues the Ran gradient and TPR import, indicating that these pathways are linked. Reducing nuclear SUMOylation decreases the nuclear mobility of the Ran nucleotide exchange factor RCC1 in vivo, and the addition of SUMO E1 and E2 promotes the dissociation of RCC1 and Ran from chromatin in vitro. Our data suggest that the cellular effects of progerin are transduced, at least in part, through reduced function of the Ran GTPase and SUMOylation pathways.

  17. 10 CFR 8.1 - Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel. 8.1 Section 8.1 Energy NUCLEAR REGULATORY COMMISSION INTERPRETATIONS § 8.1 Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General...

  18. 10 CFR 8.1 - Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel. 8.1 Section 8.1 Energy NUCLEAR REGULATORY COMMISSION INTERPRETATIONS § 8.1 Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General...

  19. 10 CFR 8.1 - Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General Counsel. 8.1 Section 8.1 Energy NUCLEAR REGULATORY COMMISSION INTERPRETATIONS § 8.1 Interpretation of section 152 of the Atomic Energy Act of 1954; opinion of the General...

  20. 75 FR 61228 - Board Meeting: Technical Lessons Gained From High-Level Nuclear Waste Disposal Efforts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: Technical Lessons Gained From High-Level... Waste Policy Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will meet in Dulles... of Energy on technical issues and to review the technical validity of DOE activities related to...

  1. Vital area identification for U.S. Nuclear Regulatory Commission nuclear power reactor licensees and new reactor applicants.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whitehead, Donnie Wayne; Varnado, G. Bruce

    2008-09-01

    U.S. Nuclear Regulatory Commission nuclear power plant licensees and new reactor applicants are required to provide protection of their plants against radiological sabotage, including the placement of vital equipment in vital areas. This document describes a systematic process for the identification of the minimum set of areas that must be designated as vital areas in order to ensure that all radiological sabotage scenarios are prevented. Vital area identification involves the use of logic models to systematically identify all of the malicious acts or combinations of malicious acts that could lead to radiological sabotage. The models available in the plant probabilisticmore » risk assessment and other safety analyses provide a great deal of the information and basic model structure needed for the sabotage logic model. Once the sabotage logic model is developed, the events (or malicious acts) in the model are replaced with the areas in which the events can be accomplished. This sabotage area logic model is then analyzed to identify the target sets (combinations of areas the adversary must visit to cause radiological sabotage) and the candidate vital area sets (combinations of areas that must be protected against adversary access to prevent radiological sabotage). Any one of the candidate vital area sets can be selected for protection. Appropriate selection criteria will allow the licensee or new reactor applicant to minimize the impacts of vital area protection measures on plant safety, cost, operations, or other factors of concern.« less

  2. Anthropology for the nuclear age

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mandelbaum, D.G.

    An anthropological approach to preparing for a turning point in the nuclear age as a result of a large-scale accident or act of terrorism suggests three areas for preliminary study: institutional changes that would reinforce international structures to be more effective in preserving the peace and would redirect military institutions toward that end; cultural changes that would deal with the fears and perceptions of citizens within each nation to find new ways of communication and conflict resolution, but keeping in mind the major class, religious, regional, and ethnic groupings; and global forces that would deal with population pressures. These preliminarymore » studies would need revision after the nuclear event to incorporate the new circumstances. 15 references.« less

  3. Making a Lasting Impression: Recovery Act Reporting At Hanford - 12528

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tebrugge, Kimberly; Disney, Maren

    The award of American Recovery and Reinvestment Act funding came with an unprecedented request for transparency to showcase to the American public how the stimulus funding was being put to work to achieve the goals put forth by the U.S. Government. At the U.S. Department of Energy Hanford Site, this request manifested in a contract requirement to provide weekly narrative, photos and video to highlight Recovery Act-funded projects. For DOE contractor CH2M HILL Plateau Remediation Company (CH2M HILL), the largest recipient of Hanford's funding, the reporting mechanism evolved into a communications tool for documenting the highly technical cleanup, then effectivelymore » sharing that story with the DOE and its varying stakeholder audiences. The report set the groundwork for building a streaming narrative of week-by-week progress. With the end of the Recovery Act, CH2M HILL is applying lessons learned from this stringent, transparent reporting process to its long-term reporting and communications of the progress being made in nuclear decommissioning at Hanford. (authors)« less

  4. 76 FR 14699 - Southern Nuclear Operating Company; Notice of Availability of Application for a Combined License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... NUCLEAR REGULATORY COMMISSION [Docket Nos. 52-025 and 52-026; NRC-2008-0252] Southern Nuclear... Atomic Energy Act and Title 10 of the Code of Federal Regulations (10 CFR) Part 52, ``Licenses... of 10 CFR Part 52. The information submitted by the applicant includes certain administrative...

  5. 76 FR 16645 - Southern Nuclear Operating Company; Notice of Availability of Application for a Combined License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... NUCLEAR REGULATORY COMMISSION [Docket Nos. 52-025 and 52-026; NRC-2008-0252] Southern Nuclear... Atomic Energy Act and Title 10 of the Code of Federal Regulations (10 CFR) Part 52, ``Licenses... of 10 CFR Part 52. The information submitted by the applicant includes certain administrative...

  6. Regulatory experience in applying a radiological environmental protection framework for existing and planned nuclear facilities.

    PubMed

    Mihok, S; Thompson, P

    2012-01-01

    Frameworks and methods for the radiological protection of non-human biota have been evolving rapidly at the International Commission on Radiological Protection and through various European initiatives. The International Atomic Energy Agency has incorporated a requirement for environmental protection in the latest revision of its Basic Safety Standards. In Canada, the Canadian Nuclear Safety Commission has been legally obligated to prevent unreasonable risk to the environment since 2000. Licensees have therefore been meeting generic legal requirements to demonstrate adequate control of releases of radioactive substances for the protection of both people and biota for many years. In the USA, in addition to the generic requirements of the Environmental Protection Agency and the Nuclear Regulatory Commission, Department of Energy facilities have also had to comply with specific dose limits after a standard assessment methodology was finalised in 2002. Canadian regulators developed a similar framework for biota dose assessment through a regulatory assessment under the Canadian Environmental Protection Act in the late 1990s. Since then, this framework has been applied extensively to satisfy legal requirements under the Canadian Environmental Assessment Act and the Nuclear Safety and Control Act. After approximately a decade of experience in applying these methods, it is clear that simple methods are fit for purpose, and can be used for making regulatory decisions for existing and planned nuclear facilities. Copyright © 2012. Published by Elsevier Ltd.

  7. Government Performance and Results Act: Performance plan FY 1999, U.S. Nuclear Regulatory Commission. Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fuches, J.L.

    1998-02-01

    The Nuclear Regulatory Commission`s (NRC) strategic plan [NUREG-1614, Vol. 1, September 1997] establishes a strategic framework that will guide future decision-making and will help the NRC continue to meet its responsibility for protecting public health and safety, promoting the common defense and security, and protecting the environment. This performance plan complements the agency`s strategic plan by setting annual goals with measurable target levels of performance for FY 1999, as required by the Government Performance and Results Act. No significant contribution was made to the preparation of the performance plan by any non-Federal entity. However, a contractor was used to helpmore » facilitate discussions and resolution of issues. Within six months after the close of FY 1999, the NRC will submit to the President and the Congress a report on program performance for FY 1999. This performance report will review the success of the agency in achieving the performance goals established for FY 1999. Where those goals have been achieved, the underlying assumptions and strategies will be examined to ensure that continued applicability is warranted in the future. If any of the FY 1999 performance goals are not met, the agency will conduct a thorough analysis of why it did not meet the goal and the actions necessary to meet-the goal in the future. One result of this analysis will be the documentation of plans and schedules for achieving the established performance goal. If the analysis should indicate that the performance goal is impractical or infeasible, the performance report will document why that is the case and what action is recommended.« less

  8. Plant nuclear hormone receptors: a role for small molecules in protein-protein interactions.

    PubMed

    Lumba, Shelley; Cutler, Sean; McCourt, Peter

    2010-01-01

    Plant hormones are a group of chemically diverse small molecules that direct processes ranging from growth and development to biotic and abiotic stress responses. Surprisingly, genome analyses suggest that classic animal nuclear hormone receptor homologs do not exist in plants. It now appears that plants have co-opted several protein families to perceive hormones within the nucleus. In one solution to the problem, the hormones auxin and jasmonate (JA) act as “molecular glue” that promotes protein-protein interactions between receptor F-boxes and downstream corepressor targets. In another solution, gibberellins (GAs) bind and elicit a conformational change in a novel soluble receptor family related to hormone-sensitive lipases. Abscisic acid (ABA), like GA, also acts through an allosteric mechanism involving a START-domain protein. The molecular identification of plant nuclear hormone receptors will allow comparisons with animal nuclear receptors and testing of fundamental questions about hormone function in plant development and evolution.

  9. The Human Cloning Prohibition Act of 2001: vagueness and federalism.

    PubMed

    Swartz, Jonathan S

    2002-01-01

    On July 31, 2001, the U.S. House of Representatives passed The Human Cloning Prohibition Act of 2001. The legislation proposes a complete ban on somatic cell nuclear transfer to create cloned human embryos; it threatens transgressors with criminal punishment and civil fines. House Bill 2505 is the first human cloning prohibition to pass either chamber of Congress. This note argues that the bill is unconstitutionally vague and inconsistent with the Supreme Court's recent Commerce Clause jurisprudence.

  10. Natural compounds regulate energy metabolism by the modulating the activity of lipid-sensing nuclear receptors.

    PubMed

    Goto, Tsuyoshi; Kim, Young-Il; Takahashi, Nobuyuki; Kawada, Teruo

    2013-01-01

    Obesity causes excess fat accumulation in various tissues, most notoriously in the adipose tissue, along with other insulin-responsive organs such as skeletal muscle and the liver, which predisposes an individual to the development of metabolic abnormalities. The molecular mechanisms underlying obesity-induced metabolic abnormalities have not been completely elucidated; however, in recent years, the search for therapies to prevent the development of obesity and obesity-associated metabolic disorders has increased. It is known that several nuclear receptors, when activated by specific ligands, regulate carbohydrate and lipid metabolism at the transcriptional level. The expression of lipid metabolism-related enzymes is directly regulated by the activity of various nuclear receptors via their interaction with specific response elements in promoters of those genes. Many natural compounds act as ligands of nuclear receptors and regulate carbohydrate and lipid metabolism by regulating the activities of these nuclear receptors. In this review, we describe our current knowledge of obesity, the role of lipid-sensing nuclear receptors in energy metabolism, and several examples of food factors that act as agonists or antagonists of nuclear receptors, which may be useful for the management of obesity and the accompanying energy metabolism abnormalities. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. The Yeast Nuclear Pore Complex and Transport Through It

    PubMed Central

    Aitchison, John D.; Rout, Michael P.

    2012-01-01

    Exchange of macromolecules between the nucleus and cytoplasm is a key regulatory event in the expression of a cell’s genome. This exchange requires a dedicated transport system: (1) nuclear pore complexes (NPCs), embedded in the nuclear envelope and composed of proteins termed nucleoporins (or “Nups”), and (2) nuclear transport factors that recognize the cargoes to be transported and ferry them across the NPCs. This transport is regulated at multiple levels, and the NPC itself also plays a key regulatory role in gene expression by influencing nuclear architecture and acting as a point of control for various nuclear processes. Here we summarize how the yeast Saccharomyces has been used extensively as a model system to understand the fundamental and highly conserved features of this transport system, revealing the structure and function of the NPC; the NPC’s role in the regulation of gene expression; and the interactions of transport factors with their cargoes, regulatory factors, and specific nucleoporins. PMID:22419078

  12. Nuclear Receptor Coactivator Function in Reproductive Physiology and Behavior

    PubMed Central

    Molenda, Heather A.; Kilts, Caitlin P.; Allen, Rachel L.; Tetel, Marc J.

    2009-01-01

    Gonadal steroid hormones act throughout the body to elicit changes in gene expression that result in profound effects on reproductive physiology and behavior. Steroid hormones exert many of these effects by binding to their respective intracellular receptors, which are members of a nuclear receptor superfamily of transcriptional activators. A variety of in vitro studies indicate that nuclear receptor coactivators are required for efficient transcriptional activity of steroid receptors. Many of these coactivators are found in a variety of steroid hormone-responsive reproductive tissues, including the reproductive tract, mammary gland, and brain. While many nuclear receptor coactivators have been investigated in vitro, we are only now beginning to understand their function in reproductive physiology and behavior. In this review, we discuss the general mechanisms of action of nuclear receptor coactivators in steroid-dependent gene transcription. We then review some recent and exciting findings on the function of nuclear receptor coactivators in steroid-dependent brain development and reproductive physiology and behavior. PMID:12855594

  13. Resolving Past Liabilities for Future Reduction in Greenhouse Gases; Nuclear Energy and the Outstanding Federal Liability of Spent Nuclear Fuel

    NASA Astrophysics Data System (ADS)

    Donohue, Jay

    This thesis will: (1) examine the current state of nuclear power in the U.S.; (2) provide a comparison of nuclear power to both existing alternative/renewable sources of energy as well as fossil fuels; (3) dissect Standard Contracts created pursuant to the National Waste Policy Act (NWPA), Congress' attempt to find a solution for Spent Nuclear Fuel (SNF), and the designation of Yucca Mountain as a repository; (4) the anticipated failure of Yucca Mountain; (5) explore WIPP as well as attempts to build a facility on Native American land in Utah; (6) examine reprocessing as a solution for SNF used by France and Japan; and, finally, (7) propose a solution to reduce GHG's by developing new nuclear energy plants with financial support from the U.S. government and a solution to build a storage facility for SNF through the sitting of a repository based on a "bottom-up" cooperative federalism approach.

  14. Nuclear Lipids in the Nervous System: What they do in Health and Disease.

    PubMed

    Garcia-Gil, Mercedes; Albi, Elisabetta

    2017-02-01

    In the last 20 years it has been widely demonstrated that cell nucleus contains neutral and polar lipids localized in nuclear membranes, nucleoli, nuclear matrix and chromatin. Nuclear lipids may show specific organization forming nuclear lipid microdomains and have both structural and functional roles. Depending on their localization, nuclear lipids play different roles such as the regulation of nuclear membrane and nuclear matrix fluidity but they also can act as platforms for vitamin and hormone function, for active chromatin anchoring, and for the regulation of gene expression, DNA duplication and transcription. Crosstalk among different kinds of lipid signalling pathways influence the physiopathology of numerous cell types. In neural cells the nuclear lipids are involved in cell proliferation, differentiation, inflammation, migration and apoptosis. Abnormal metabolism of nuclear lipids might be closely associated with tumorigenesis and neurodegenerative diseases such as Alzheimer disease and Parkinson disease among others.

  15. The Defective Nuclear Lamina in Hutchinson-Gilford Progeria Syndrome Disrupts the Nucleocytoplasmic Ran Gradient and Inhibits Nuclear Localization of Ubc9▿

    PubMed Central

    Kelley, Joshua B.; Datta, Sutirtha; Snow, Chelsi J.; Chatterjee, Mandovi; Ni, Li; Spencer, Adam; Yang, Chun-Song; Cubeñas-Potts, Caelin; Matunis, Michael J.; Paschal, Bryce M.

    2011-01-01

    The mutant form of lamin A responsible for the premature aging disease Hutchinson-Gilford progeria syndrome (termed progerin) acts as a dominant negative protein that changes the structure of the nuclear lamina. How the perturbation of the nuclear lamina in progeria is transduced into cellular changes is undefined. Using patient fibroblasts and a variety of cell-based assays, we determined that progerin expression in Hutchinson-Gilford progeria syndrome inhibits the nucleocytoplasmic transport of several factors with key roles in nuclear function. We found that progerin reduces the nuclear/cytoplasmic concentration of the Ran GTPase and inhibits the nuclear localization of Ubc9, the sole E2 for SUMOylation, and of TPR, the nucleoporin that forms the basket on the nuclear side of the nuclear pore complex. Forcing the nuclear localization of Ubc9 in progerin-expressing cells rescues the Ran gradient and TPR import, indicating that these pathways are linked. Reducing nuclear SUMOylation decreases the nuclear mobility of the Ran nucleotide exchange factor RCC1 in vivo, and the addition of SUMO E1 and E2 promotes the dissociation of RCC1 and Ran from chromatin in vitro. Our data suggest that the cellular effects of progerin are transduced, at least in part, through reduced function of the Ran GTPase and SUMOylation pathways. PMID:21670151

  16. Bubblers Speed Nuclear Waste Processing at SRS

    ScienceCinema

    None

    2018-05-23

    At the Department of Energy's Savannah River Site, American Recovery and Reinvestment Act funding has supported installation of bubbler technology and related enhancements in the Defense Waste Processing Facility (DWPF). The improvements will accelerate the processing of radioactive waste into a safe, stable form for storage and permit expedited closure of underground waste tanks holding 37 million gallons of liquid nuclear waste.

  17. The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, Extradenticle, and suppresses eye development in Drosophila

    PubMed Central

    Pai, Chi-Yun; Kuo, Tung-Sheng; Jaw, Thomas J.; Kurant, Estee; Chen, Cheng-Tse; Bessarab, Dmitri A.; Salzberg, Adi; Sun, Y. Henry

    1998-01-01

    The Extradenticle (Exd) protein in Drosophila acts as a cofactor to homeotic proteins. Its nuclear localization is regulated. We report the cloning of the Drosophila homothorax (hth) gene, a homolog of the mouse Meis1 proto-oncogene that has a homeobox related to that of exd. Comparison with Meis1 finds two regions of high homology: a novel MH domain and the homeodomain. In imaginal discs, hth expression coincides with nuclear Exd. hth and exd also have virtually identical, mutant clonal phenotypes in adults. These results suggest that hth and exd function in the same pathway. We show that hth acts upstream of exd and is required and sufficient for Exd protein nuclear localization. We also show that hth and exd are both negative regulators of eye development; their mutant clones caused ectopic eye formation. Targeted expression of hth, but not of exd, in the eye disc abolished eye development completely. We suggest that hth acts with exd to delimit the eye field and prevent inappropriate eye development. PMID:9450936

  18. Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture

    PubMed Central

    Ding, Zhao-Ying; Huang, Yu-Cheng; Lee, Myong-Chol; Tseng, Min-Jen; Chi, Ya-Hui

    2017-01-01

    Linker of nucleoskeleton and cytoskeleton (LINC) complexes spanning the nuclear envelope (NE) contribute to nucleocytoskeletal force transduction. A few NE proteins have been found to regulate the LINC complex. In this study, we identify one, Kuduk (Kud), which can reside at the outer nuclear membrane and is required for the development of Drosophila melanogaster ovarian follicles and NE morphology of myonuclei. Kud associates with LINC complex components in an evolutionarily conserved manner. Loss of Kud increases the level but impairs functioning of the LINC complex. Overexpression of Kud suppresses NE targeting of cytoskeleton-free LINC complexes. Thus, Kud acts as a quality control mechanism for LINC-mediated nucleocytoskeletal connections. Genetic data indicate that Kud also functions independently of the LINC complex. Overexpression of the human orthologue TMEM258 in Drosophila proved functional conservation. These findings expand our understanding of the regulation of LINC complexes and NE architecture. PMID:28716842

  19. National Environmental Policy Act Hazards Assessment for the TREAT Alternative

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boyd D. Christensen; Annette L. Schafer

    2013-11-01

    This document provides an assessment of hazards as required by the National Environmental Policy Act for the alternative of restarting the reactor at the Transient Reactor Test (TREAT) facility by the Resumption of Transient Testing Program. Potential hazards have been identified and screening level calculations have been conducted to provide estimates of unmitigated dose consequences that could be incurred through this alternative. Consequences considered include those related to use of the TREAT Reactor, experiment assembly handling, and combined events involving both the reactor and experiments. In addition, potential safety structures, systems, and components for processes associated with operating TREAT andmore » onsite handling of nuclear fuels and experiments are listed. If this alternative is selected, a safety basis will be prepared in accordance with 10 CFR 830, “Nuclear Safety Management,” Subpart B, “Safety Basis Requirements.”« less

  20. National Environmental Policy Act Hazards Assessment for the TREAT Alternative

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christensen, Boyd D.; Schafer, Annette L.

    2014-02-01

    This document provides an assessment of hazards as required by the National Environmental Policy Act for the alternative of restarting the reactor at the Transient Reactor Test (TREAT) facility by the Resumption of Transient Testing Program. Potential hazards have been identified and screening level calculations have been conducted to provide estimates of unmitigated dose consequences that could be incurred through this alternative. Consequences considered include those related to use of the TREAT Reactor, experiment assembly handling, and combined events involving both the reactor and experiments. In addition, potential safety structures, systems, and components for processes associated with operating TREAT andmore » onsite handling of nuclear fuels and experiments are listed. If this alternative is selected, a safety basis will be prepared in accordance with 10 CFR 830, “Nuclear Safety Management,” Subpart B, “Safety Basis Requirements.”« less

  1. Privacy Act

    EPA Pesticide Factsheets

    Learn about the Privacy Act of 1974, the Electronic Government Act of 2002, the Federal Information Security Management Act, and other information about the Environmental Protection Agency maintains its records.

  2. Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase.

    PubMed

    dos Santos, Marcos Tadeu; Trindade, Daniel Maragno; Gonçalves, Kaliandra de Almeida; Bressan, Gustavo Costa; Anastassopoulos, Filipe; Yunes, José Andres; Kobarg, Jörg

    2011-01-01

    Human stanniocalcin-1 (STC1) is a glycoprotein that has been implicated in different physiological process, including angiogenesis, apoptosis and carcinogenesis. Here we identified STC1 as a putative molecular marker for the leukemic bone marrow microenvironment and identified new interacting protein partners for STC1. Seven selected interactions retrieved from yeast two-hybrid screens were confirmed by GST-pull down assays in vitro. The N-terminal region was mapped to be the region that mediates the interaction with cytoplasmic, mitochondrial and nuclear proteins. STC1 interacts with SUMO-1 and several proteins that have been shown to be SUMOylated and localized to SUMOylation related nuclear bodies. Although STC1 interacts with SUMO-1 and has a high theoretical prediction score for a SUMOylation site, endogenous co-immunoprecipitation and in vitro SUMOylation assays with the purified recombinant protein could not detect STC1 SUMOylation. However, when we tested STC1 for SUMO E3 ligase activity, we found in an in vitro assay, that it significantly increases the SUMOylation of two other proteins. Confocal microscopic subcellular localization studies using both transfected cells and specific antibodies for endogenous STC1 revealed a cytoplasmic and nuclear deposition, the latter in the form of some specific dot-like substructure resembling SUMOylation related nuclear bodies. Together, these findings suggest a new role for STC1 in SUMOylation pathways, in nuclear bodies.

  3. 76 FR 47613 - Board Meeting: September 13-14, 2011-Salt Lake City, UT; the U.S. Nuclear Waste Technical Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... NUCLEAR WASTE TECHNICAL REVIEW BOARD Board Meeting: September 13-14, 2011--Salt Lake City, UT; the U.S. Nuclear Waste Technical Review Board Will Meet To Discuss DOE Plans for Used Fuel Disposition R... Amendments Act of 1987, the U.S. Nuclear Waste Technical Review Board will hold a public meeting in Salt Lake...

  4. Endothelial nuclear lamina is not required for glucocorticoid receptor nuclear import but does affect receptor-mediated transcription activation.

    PubMed

    Nayebosadri, Arman; Ji, Julie Y

    2013-08-01

    The lamina serves to maintain the nuclear structure and stiffness while acting as a scaffold for heterochromatin and many transcriptional proteins. Its role in endothelial mechanotransduction, specifically how nuclear mechanics impact gene regulation under shear stress, is not fully understood. In this study, we successfully silenced lamin A/C in bovine aortic endothelial cells to determine its role in both glucocorticoid receptor (GR) nuclear translocation and glucocorticoid response element (GRE) transcriptional activation in response to dexamethasone and shear stress. Nuclear translocation of GR, an anti-inflammatory nuclear receptor, in response to dexamethasone or shear stress (5, 10, and 25 dyn/cm(2)) was observed via time-lapse cell imaging and quantified using a Bayesian image analysis algorithm. Transcriptional activity of the GRE promoter was assessed using a dual-luciferase reporter plasmid. We found no dependence on nuclear lamina for GR translocation from the cytoplasm into the nucleus. However, the absence of lamin A/C led to significantly increased expression of luciferase under dexamethasone and shear stress induction as well as changes in histone protein function. PCR results for NF-κB inhibitor alpha (NF-κBIA) and dual specificity phosphatase 1 (DUSP1) genes further supported our luciferase data with increased expression in the absence of lamin. Our results suggest that absence of lamin A/C does not hinder passage of GR into the nucleus, but nuclear lamina is important to properly regulate GRE transcription. Nuclear lamina, rather than histone deacetylase (HDAC), is a more significant mediator of shear stress-induced transcriptional activity, while dexamethasone-initiated transcription is more HDAC dependent. Our findings provide more insights into the molecular pathways involved in nuclear mechanotransduction.

  5. Endothelial nuclear lamina is not required for glucocorticoid receptor nuclear import but does affect receptor-mediated transcription activation

    PubMed Central

    Nayebosadri, Arman

    2013-01-01

    The lamina serves to maintain the nuclear structure and stiffness while acting as a scaffold for heterochromatin and many transcriptional proteins. Its role in endothelial mechanotransduction, specifically how nuclear mechanics impact gene regulation under shear stress, is not fully understood. In this study, we successfully silenced lamin A/C in bovine aortic endothelial cells to determine its role in both glucocorticoid receptor (GR) nuclear translocation and glucocorticoid response element (GRE) transcriptional activation in response to dexamethasone and shear stress. Nuclear translocation of GR, an anti-inflammatory nuclear receptor, in response to dexamethasone or shear stress (5, 10, and 25 dyn/cm2) was observed via time-lapse cell imaging and quantified using a Bayesian image analysis algorithm. Transcriptional activity of the GRE promoter was assessed using a dual-luciferase reporter plasmid. We found no dependence on nuclear lamina for GR translocation from the cytoplasm into the nucleus. However, the absence of lamin A/C led to significantly increased expression of luciferase under dexamethasone and shear stress induction as well as changes in histone protein function. PCR results for NF-κB inhibitor alpha (NF-κBIA) and dual specificity phosphatase 1 (DUSP1) genes further supported our luciferase data with increased expression in the absence of lamin. Our results suggest that absence of lamin A/C does not hinder passage of GR into the nucleus, but nuclear lamina is important to properly regulate GRE transcription. Nuclear lamina, rather than histone deacetylase (HDAC), is a more significant mediator of shear stress-induced transcriptional activity, while dexamethasone-initiated transcription is more HDAC dependent. Our findings provide more insights into the molecular pathways involved in nuclear mechanotransduction. PMID:23703529

  6. The Trilateral Force: The Atlantic Alliance and the Future of Nuclear Weapons Strategy

    DTIC Science & Technology

    2013-12-03

    Western World, Atlantic Council (2013), 46. s Paul Bracken, The Second Nuclear Age: Strategy, Danger, and the New Power Politics (New York: Times...Studies Institute (2013); Paul Bracken, "The Bomb Returns for a Second Act," Foreign Policy Research Institute E- Notes, November (2012). 11 David...Commission Report: Modernizing US. Nuclear Strategy, Force Structure and Posture, Global Zero (2012), 6. 27 Dana Johnson, et al., "Triad, Dyad, Monad

  7. Millimeter wave detection of nuclear radiation: an alternative detection mechanism.

    PubMed

    Gopalsami, N; Chien, H T; Heifetz, A; Koehl, E R; Raptis, A C

    2009-08-01

    We present a nuclear radiation detection mechanism using millimeter waves as an alternative to conventional detection. It is based on the concept that nuclear radiation causes ionization of air and that if we place a dielectric material near the radiation source, it acts as a charge accumulator of the air ions. We have found that millimeter waves can interrogate the charge cloud on the dielectric material remotely. This concept was tested with a standoff millimeter wave system by monitoring the charge levels on a cardboard tube placed in an x-ray beam.

  8. Confronting Emergent Nuclear-Armed Regional Adversaries: Prospects for Neutralization, Strategies for Escalation Management

    DTIC Science & Technology

    2015-01-01

    might find multiple ways to blur the nuclear threshold if pushed to acts of desperation. Instead of expending all of its weapons in one suicidal ...the temptation (and any allied pressure) to punish the enemy or add demands that would significantly exceed the status quo ante bellum. Ultimately...multiple options at their disposal if pushed to acts of desperation. Instead of expending all of their weapons in one suicidal spasm, a savvy

  9. Commercial Nuclear Reprocessing in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sherrill, Charles Leland; Balatsky, Galya Ivanovna

    2015-09-09

    The short presentation outline: Reprocessing Overview; Events leading up to Carter’s Policy; Results of the decision; Policy since Nuclear Nonproliferation Act. Conclusions reached: Reprocessing ban has become an easy and visible fix to the public concern about proliferation, but has not completely stopped proliferation; and, Reprocessing needs to become detached from political considerations, so technical research can continue, regardless of the policy decisions we decide to take.

  10. 13 CFR 107.115 - 1940 Act and 1980 Act Companies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false 1940 Act and 1980 Act Companies. 107.115 Section 107.115 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Qualifying for an SBIC License Organizing An Sbic § 107.115 1940 Act and 1980 Act...

  11. 9 CFR 55.2 - Payment of indemnity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.2 Payment of indemnity. The Administrator is...

  12. 9 CFR 55.2 - Payment of indemnity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.2 Payment of indemnity. The Administrator is...

  13. 9 CFR 55.4 - Disinfection of premises, conveyances, and materials.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.4 Disinfection of...

  14. 9 CFR 55.5 - Presentation of claims for indemnity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.5 Presentation of claims for...

  15. 9 CFR 55.5 - Presentation of claims for indemnity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.5 Presentation of claims for...

  16. 9 CFR 55.5 - Presentation of claims for indemnity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.5 Presentation of claims for...

  17. 9 CFR 55.2 - Payment of indemnity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.2 Payment of indemnity. The Administrator is...

  18. 9 CFR 55.2 - Payment of indemnity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.2 Payment of indemnity. The Administrator is...

  19. 9 CFR 55.4 - Disinfection of premises, conveyances, and materials.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.4 Disinfection of...

  20. 9 CFR 55.5 - Presentation of claims for indemnity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.5 Presentation of claims for...

  1. 9 CFR 55.5 - Presentation of claims for indemnity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.5 Presentation of claims for...

  2. 9 CFR 55.2 - Payment of indemnity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.2 Payment of indemnity. The Administrator is...

  3. 9 CFR 55.4 - Disinfection of premises, conveyances, and materials.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.4 Disinfection of...

  4. NUCLEAR REACTOR

    DOEpatents

    Miller, H.I.; Smith, R.C.

    1958-01-21

    This patent relates to nuclear reactors of the type which use a liquid fuel, such as a solution of uranyl sulfate in ordinary water which acts as the moderator. The reactor is comprised of a spherical vessel having a diameter of about 12 inches substantially surrounded by a reflector of beryllium oxide. Conventionnl control rods and safety rods are operated in slots in the reflector outside the vessel to control the operation of the reactor. An additional means for increasing the safety factor of the reactor by raising the ratio of delayed neutrons to prompt neutrons, is provided and consists of a soluble sulfate salt of beryllium dissolved in the liquid fuel in the proper proportion to obtain the result desired.

  5. Sabotage at Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Purvis, James W.

    1999-07-21

    Recently there has been a noted worldwide increase in violent actions including attempted sabotage at nuclear power plants. Several organizations, such as the International Atomic Energy Agency and the US Nuclear Regulatory Commission, have guidelines, recommendations, and formal threat- and risk-assessment processes for the protection of nuclear assets. Other examples are the former Defense Special Weapons Agency, which used a risk-assessment model to evaluate force-protection security requirements for terrorist incidents at DOD military bases. The US DOE uses a graded approach to protect its assets based on risk and vulnerability assessments. The Federal Aviation Administration and Federal Bureau of Investigationmore » conduct joint threat and vulnerability assessments on high-risk US airports. Several private companies under contract to government agencies use formal risk-assessment models and methods to identify security requirements. The purpose of this paper is to survey these methods and present an overview of all potential types of sabotage at nuclear power plants. The paper discusses emerging threats and current methods of choice for sabotage--especially vehicle bombs and chemical attacks. Potential consequences of sabotage acts, including economic and political; not just those that may result in unacceptable radiological exposure to the public, are also discussed. Applicability of risk-assessment methods and mitigation techniques are also presented.« less

  6. Nuclear Mitochondrial DNA Activates Replication in Saccharomyces cerevisiae

    PubMed Central

    Chatre, Laurent; Ricchetti, Miria

    2011-01-01

    The nuclear genome of eukaryotes is colonized by DNA fragments of mitochondrial origin, called NUMTs. These insertions have been associated with a variety of germ-line diseases in humans. The significance of this uptake of potentially dangerous sequences into the nuclear genome is unclear. Here we provide functional evidence that sequences of mitochondrial origin promote nuclear DNA replication in Saccharomyces cerevisiae. We show that NUMTs are rich in key autonomously replicating sequence (ARS) consensus motifs, whose mutation results in the reduction or loss of DNA replication activity. Furthermore, 2D-gel analysis of the mrc1 mutant exposed to hydroxyurea shows that several NUMTs function as late chromosomal origins. We also show that NUMTs located close to or within ARS provide key sequence elements for replication. Thus NUMTs can act as independent origins, when inserted in an appropriate genomic context or affect the efficiency of pre-existing origins. These findings show that migratory mitochondrial DNAs can impact on the replication of the nuclear region they are inserted in. PMID:21408151

  7. Nuclear mitochondrial DNA activates replication in Saccharomyces cerevisiae.

    PubMed

    Chatre, Laurent; Ricchetti, Miria

    2011-03-08

    The nuclear genome of eukaryotes is colonized by DNA fragments of mitochondrial origin, called NUMTs. These insertions have been associated with a variety of germ-line diseases in humans. The significance of this uptake of potentially dangerous sequences into the nuclear genome is unclear. Here we provide functional evidence that sequences of mitochondrial origin promote nuclear DNA replication in Saccharomyces cerevisiae. We show that NUMTs are rich in key autonomously replicating sequence (ARS) consensus motifs, whose mutation results in the reduction or loss of DNA replication activity. Furthermore, 2D-gel analysis of the mrc1 mutant exposed to hydroxyurea shows that several NUMTs function as late chromosomal origins. We also show that NUMTs located close to or within ARS provide key sequence elements for replication. Thus NUMTs can act as independent origins, when inserted in an appropriate genomic context or affect the efficiency of pre-existing origins. These findings show that migratory mitochondrial DNAs can impact on the replication of the nuclear region they are inserted in.

  8. Lessons learned from the post-emergency TABLETOP exercise in Baton Rouge, Louisiana, on August 28 and September 18, 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1991-07-01

    On August 28 and September 18, 1990, Gulf States Utilities, the States of Louisiana and Mississippi, five local parishes, six Federal agencies, and the American Nuclear Insurers participated in a post-emergency TABLETOP exercise in Baton Rouge, Louisiana. The purpose of the exercise was to examine the post-emergency roles, responsibilities, and resources of utility, State, local, Federal and insurance organizations in response to a hypothetical accident at the River Bend Station in Louisiana resulting in a significant release of radiation to the environment. In pursuit of this goal, five major focus areas were addressed: (1) ingestion pathway response; (2) reentry, relocationmore » and return; (3) decontamination of recovery; (4) indemnification of financial losses; and (5) deactivation of the emergency response. This report documents the lessons learned from that exercise.« less

  9. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.

    PubMed

    Wang, Wei-jia; Wang, Yuan; Chen, Hang-zi; Xing, Yong-zhen; Li, Feng-wei; Zhang, Qian; Zhou, Bo; Zhang, Hong-kui; Zhang, Jie; Bian, Xue-li; Li, Li; Liu, Yuan; Zhao, Bi-xing; Chen, Yan; Wu, Rong; Li, An-zhong; Yao, Lu-ming; Chen, Ping; Zhang, Yi; Tian, Xu-yang; Beermann, Friedrich; Wu, Mian; Han, Jiahuai; Huang, Pei-qiang; Lin, Tianwei; Wu, Qiao

    2014-02-01

    Autophagy is linked to cell death, yet the associated mechanisms are largely undercharacterized. We discovered that melanoma, which is generally resistant to drug-induced apoptosis, can undergo autophagic cell death with the participation of orphan nuclear receptor TR3. A sequence of molecular events leading to cellular demise is launched by a specific chemical compound, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, newly acquired from screening a library of TR3-targeting compounds. The autophagic cascade comprises TR3 translocation to mitochondria through interaction with the mitochondrial outer membrane protein Nix, crossing into the mitochondrial inner membrane through Tom40 and Tom70 channel proteins, dissipation of mitochondrial membrane potential by the permeability transition pore complex ANT1-VDAC1 and induction of autophagy. This process leads to excessive mitochondria clearance and irreversible cell death. It implicates a new approach to melanoma therapy through activation of a mitochondrial signaling pathway that integrates a nuclear receptor with autophagy for cell death.

  10. Dynamic Assembly of Brambleberry Mediates Nuclear Envelope Fusion during Early Development

    PubMed Central

    Abrams, Elliott W.; Zhang, Hong; Marlow, Florence L.; Kapp, Lee; Lu, Sumei; Mullins, Mary C.

    2012-01-01

    Summary To accommodate the large cells following zygote formation, early blastomeres employ modified cell divisions. Karyomeres are one such modification, a mitotic intermediate wherein individual chromatin masses are surrounded by nuclear envelope, which then fuse to form a single mononucleus. We identified brambleberry, a maternal-effect zebrafish mutant that disrupts karyomere fusion resulting in formation of multiple micronuclei. brambleberry is a previously unannotated gene homologous to Kar5p, which participates in nuclear fusion in yeast. We demonstrate that Brambleberry is required for pronuclear fusion following fertilization in zebrafish. As karyomeres form, Brambleberry localizes to the nuclear envelope with prominent puncta evident near karyomere-karyomere interfaces corresponding to membrane fusion sites. Our studies identify the first factor acting in karyomere fusion and suggest that specialized proteins are necessary for proper nuclear division in large dividing blastomeres. PMID:22863006

  11. 48 CFR 970.5226-2 - Workforce restructuring under section 3161 of the National Defense Authorization Act for fiscal...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... a change in workforce at a Department of Energy Defense Nuclear Facility is necessary, the... under section 3161 of the National Defense Authorization Act for fiscal year 1993. 970.5226-2 Section... and Operating Contracts 970.5226-2 Workforce restructuring under section 3161 of the National Defense...

  12. Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.

    PubMed

    Fung, Ho Yee Joyce; Fu, Szu-Chin; Chook, Yuh Min

    2017-03-10

    Nuclear export receptor CRM1 binds highly variable nuclear export signals (NESs) in hundreds of different cargoes. Previously we have shown that CRM1 binds NESs in both polypeptide orientations (Fung et al., 2015). Here, we show crystal structures of CRM1 bound to eight additional NESs which reveal diverse conformations that range from loop-like to all-helix, which occupy different extents of the invariant NES-binding groove. Analysis of all NES structures show 5-6 distinct backbone conformations where the only conserved secondary structural element is one turn of helix that binds the central portion of the CRM1 groove. All NESs also participate in main chain hydrogen bonding with human CRM1 Lys568 side chain, which acts as a specificity filter that prevents binding of non-NES peptides. The large conformational range of NES backbones explains the lack of a fixed pattern for its 3-5 hydrophobic anchor residues, which in turn explains the large array of peptide sequences that can function as NESs.

  13. 75 FR 36535 - Freedom of Information Act, Privacy Act of 1974; Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... Freedom of Information Act (FOIA) and its regulations concerning the Privacy Act of 1974 (Privacy Act). It..., Privacy Act of 1974; Implementation AGENCY: Department of the Treasury. ACTION: Final rule; correcting... the Privacy Act. In addition, that document revised the list of Treasury offices and bureaus found...

  14. 76 FR 64115 - Privacy Act of 1974; Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-092)] Privacy Act of 1974; Privacy Act... retirement of one Privacy Act system of records notice. SUMMARY: In accordance with the Privacy Act of 1974, NASA is giving notice that it proposes to cancel the following Privacy Act system of records notice...

  15. 75 FR 743 - Freedom of Information Act, Privacy Act of 1974; Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-06

    ... of Information Act (FOIA) and its regulations concerning the Privacy Act of 1974 (Privacy Act). It..., Privacy Act of 1974; Implementation AGENCY: Department of the Treasury. ACTION: Final rule. SUMMARY: This... implement the Privacy Act. In addition, the document revises the list of Treasury offices and bureaus found...

  16. 48 CFR 970.5226-2 - Workforce restructuring under section 3161 of the National Defense Authorization Act for fiscal...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... workforce at a Department of Energy Defense Nuclear Facility is necessary, the contractor agrees to (1... under section 3161 of the National Defense Authorization Act for fiscal year 1993. 970.5226-2 Section... and Operating Contracts 970.5226-2 Workforce restructuring under section 3161 of the National Defense...

  17. 48 CFR 970.5226-2 - Workforce restructuring under section 3161 of the National Defense Authorization Act for fiscal...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... workforce at a Department of Energy Defense Nuclear Facility is necessary, the contractor agrees to (1... under section 3161 of the National Defense Authorization Act for fiscal year 1993. 970.5226-2 Section... and Operating Contracts 970.5226-2 Workforce restructuring under section 3161 of the National Defense...

  18. 48 CFR 970.5226-2 - Workforce restructuring under section 3161 of the National Defense Authorization Act for fiscal...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... workforce at a Department of Energy Defense Nuclear Facility is necessary, the contractor agrees to (1... under section 3161 of the National Defense Authorization Act for fiscal year 1993. 970.5226-2 Section... and Operating Contracts 970.5226-2 Workforce restructuring under section 3161 of the National Defense...

  19. 48 CFR 970.5226-2 - Workforce restructuring under section 3161 of the National Defense Authorization Act for fiscal...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... workforce at a Department of Energy Defense Nuclear Facility is necessary, the contractor agrees to (1... under section 3161 of the National Defense Authorization Act for fiscal year 1993. 970.5226-2 Section... and Operating Contracts 970.5226-2 Workforce restructuring under section 3161 of the National Defense...

  20. Uncovering many-body correlations in nanoscale nuclear spin baths by central spin decoherence

    PubMed Central

    Ma, Wen-Long; Wolfowicz, Gary; Zhao, Nan; Li, Shu-Shen; Morton, John J.L.; Liu, Ren-Bao

    2014-01-01

    Central spin decoherence caused by nuclear spin baths is often a critical issue in various quantum computing schemes, and it has also been used for sensing single-nuclear spins. Recent theoretical studies suggest that central spin decoherence can act as a probe of many-body physics in spin baths; however, identification and detection of many-body correlations of nuclear spins in nanoscale systems are highly challenging. Here, taking a phosphorus donor electron spin in a 29Si nuclear spin bath as our model system, we discover both theoretically and experimentally that many-body correlations in nanoscale nuclear spin baths produce identifiable signatures in decoherence of the central spin under multiple-pulse dynamical decoupling control. We demonstrate that under control by an odd or even number of pulses, the central spin decoherence is principally caused by second- or fourth-order nuclear spin correlations, respectively. This study marks an important step toward studying many-body physics using spin qubits. PMID:25205440

  1. Tumour suppressor TRIM33 targets nuclear β-catenin degradation

    PubMed Central

    Xue, Jianfei; Chen, Yaohui; Wu, Yamei; Wang, Zhongyong; Zhou, Aidong; Zhang, Sicong; Lin, Kangyu; Aldape, Kenneth; Majumder, Sadhan; Lu, Zhimin; Huang, Suyun

    2014-01-01

    Aberrant activation of β-catenin in the nucleus has been implicated in a variety of human cancers but the fate of nuclear β-catenin is unknown. Here we demonstrate that tripartite motif-containing protein 33 (TRIM33), acting as an E3 ubiquitin ligase, reduces the abundance of nuclear β-catenin protein. TRIM33-mediated β-catenin is destabilized and is GSK-3β or β-TrCP independent. TRIM33 interacts with and ubiquitylates nuclear β-catenin. Moreover, protein kinase Cδ, which directly phosphorylates β-catenin at Ser715, is required for the TRIM33–β-catenin interaction. The function of TRIM33 in suppressing tumour cell proliferation and brain tumour development depends on TRIM33-promoted β-catenin degradation. In human glioblastoma specimens, endogenous TRIM33 levels are inversely correlated with β-catenin. In summary, our findings identify TRIM33 as a tumour suppressor that can abolish tumour cell proliferation and tumorigenesis by degrading nuclear β-catenin. This work suggests a new therapeutic strategy against human cancers caused by aberrant activation of β-catenin. PMID:25639486

  2. Autophagy mediates degradation of nuclear lamina.

    PubMed

    Dou, Zhixun; Xu, Caiyue; Donahue, Greg; Shimi, Takeshi; Pan, Ji-An; Zhu, Jiajun; Ivanov, Andrejs; Capell, Brian C; Drake, Adam M; Shah, Parisha P; Catanzaro, Joseph M; Ricketts, M Daniel; Lamark, Trond; Adam, Stephen A; Marmorstein, Ronen; Zong, Wei-Xing; Johansen, Terje; Goldman, Robert D; Adams, Peter D; Berger, Shelley L

    2015-11-05

    Macroautophagy (hereafter referred to as autophagy) is a catabolic membrane trafficking process that degrades a variety of cellular constituents and is associated with human diseases. Although extensive studies have focused on autophagic turnover of cytoplasmic materials, little is known about the role of autophagy in degrading nuclear components. Here we report that the autophagy machinery mediates degradation of nuclear lamina components in mammals. The autophagy protein LC3/Atg8, which is involved in autophagy membrane trafficking and substrate delivery, is present in the nucleus and directly interacts with the nuclear lamina protein lamin B1, and binds to lamin-associated domains on chromatin. This LC3-lamin B1 interaction does not downregulate lamin B1 during starvation, but mediates its degradation upon oncogenic insults, such as by activated RAS. Lamin B1 degradation is achieved by nucleus-to-cytoplasm transport that delivers lamin B1 to the lysosome. Inhibiting autophagy or the LC3-lamin B1 interaction prevents activated RAS-induced lamin B1 loss and attenuates oncogene-induced senescence in primary human cells. Our study suggests that this new function of autophagy acts as a guarding mechanism protecting cells from tumorigenesis.

  3. 48 CFR 50.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... identifying the risks insured against and the coverage extended to persons or property, or both; (C) Dollar... unusually hazardous or nuclear risks. 50.104-3 Section 50.104-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT...

  4. Understanding the Value of a Computer Emergency Response Capability for Nuclear Security

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gasper, Peter Donald; Rodriguez, Julio Gallardo

    The international nuclear community has a great understanding of the physical security needs relating to the prevention, detection, and response of malicious acts associated with nuclear facilities and radioactive material. International Atomic Energy Agency (IAEA) Nuclear Security Recommendations (INFCIRC_225_Rev 5) outlines specific guidelines and recommendations for implementing and maintaining an organization’s nuclear security posture. An important element for inclusion into supporting revision 5 is the establishment of a “Cyber Emergency Response Team (CERT)” focused on the international communities cybersecurity needs to maintain a comprehensive nuclear security posture. Cybersecurity and the importance of nuclear cybersecurity require that there be a specificmore » focus on developing an International Nuclear CERT (NS-CERT). States establishing contingency plans should have an understanding of the cyber threat landscape and the potential impacts to systems in place to protect and mitigate malicious activities. This paper will outline the necessary components, discuss the relationships needed within the international community, and outline a process by which the NS-CERT identifies, collects, processes, and reports critical information in order to establish situational awareness (SA) and support decision-making« less

  5. ACTS Experiments Program

    NASA Technical Reports Server (NTRS)

    Schertler, R. J.

    1986-01-01

    An overview of the ACTS Experiments Program is presented. ACTS is being developed and will flight test the advanced technologies associated with: a Ka-band multibeam antenna, onboard signal processing and switching as well as laser communications. A nominal 3 yr experiments program is planned. Through the experiments program, the capabilities of the ACTS system will be made available to U.S. industry, university and government experimenters to test, prove the feasibility and evaluate the key ACTS system technologies. Communication modes of operation using the baseband processor and microwave switch matrix are presented, along with the antenna coverage pattern. Potential experiment categories are also presented and briefly discussed. An overall schedule of activities associated with the experiments program is outlined. Results of the ACTS Experiments Program will provide information vital to successful industry implementation of ACTS technology in a future operational system.

  6. 75 FR 21368 - South Carolina Electric and Gas Acting for Itself and as an Agent for South Carolina Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... NUCLEAR REGULATORY COMMISSION [Docket No. 52-027 and 52-028; NRC-2008-0441] South Carolina Electric and Gas Acting for Itself and as an Agent for South Carolina Public Service Authority (Also Referred to as Santee Cooper) Notice of Availability of the Draft Environmental Impact Statement for the...

  7. Nuclear security policy in the context of counter-terrorism in Cambodia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khun, Vuthy, E-mail: vuthy.khun@gmail.com; Wongsawaeng, Doonyapong

    The risk of nuclear or dirty bomb attack by terrorists is one of the most urgent and threatening danger. The Cambodian national strategy to combat weapons of mass destruction (WMD) depicts a layered system of preventive measures ranging from securing materials at foreign sources to interdicting weapons or nuclear or other radioactive materials at ports, border crossings, and within the Cambodian institutions dealing with the nuclear security to manage the preventive programs. The aim of this study is to formulate guidance, to identify scenario of threat and risk, and to pinpoint necessary legal frameworks on nuclear security in the contextmore » of counterterrorism based on the International Atomic Energy Agency nuclear security series. The analysis of this study is guided by theoretical review, the review of international laws and politics, by identifying and interpreting applicable rules and norms establishing the nuclear security regime and how well enforcement of the regime is carried out and, what is the likelihood of the future reform might be. This study will examine the existing national legal frameworks of Cambodia in the context of counterterrorism to prevent acts of nuclear terrorism and the threat of a terrorist nuclear attack within the Cambodia territory. It will shed light on departmental lanes of national nuclear security responsibility, and provide a holistic perspective on the needs of additional resources and emphasis regarding nuclear security policy in the context of counterterrorism in Cambodia.« less

  8. Nuclear security policy in the context of counter-terrorism in Cambodia

    NASA Astrophysics Data System (ADS)

    Khun, Vuthy; Wongsawaeng, Doonyapong

    2016-01-01

    The risk of nuclear or dirty bomb attack by terrorists is one of the most urgent and threatening danger. The Cambodian national strategy to combat weapons of mass destruction (WMD) depicts a layered system of preventive measures ranging from securing materials at foreign sources to interdicting weapons or nuclear or other radioactive materials at ports, border crossings, and within the Cambodian institutions dealing with the nuclear security to manage the preventive programs. The aim of this study is to formulate guidance, to identify scenario of threat and risk, and to pinpoint necessary legal frameworks on nuclear security in the context of counterterrorism based on the International Atomic Energy Agency nuclear security series. The analysis of this study is guided by theoretical review, the review of international laws and politics, by identifying and interpreting applicable rules and norms establishing the nuclear security regime and how well enforcement of the regime is carried out and, what is the likelihood of the future reform might be. This study will examine the existing national legal frameworks of Cambodia in the context of counterterrorism to prevent acts of nuclear terrorism and the threat of a terrorist nuclear attack within the Cambodia territory. It will shed light on departmental lanes of national nuclear security responsibility, and provide a holistic perspective on the needs of additional resources and emphasis regarding nuclear security policy in the context of counterterrorism in Cambodia.

  9. Nuclear speckles: molecular organization, biological function and role in disease

    PubMed Central

    Galganski, Lukasz; Urbanek, Martyna O.

    2017-01-01

    Abstract The nucleoplasm is not homogenous; it consists of many types of nuclear bodies, also known as nuclear domains or nuclear subcompartments. These self-organizing structures gather machinery involved in various nuclear activities. Nuclear speckles (NSs) or splicing speckles, also called interchromatin granule clusters, were discovered as sites for splicing factor storage and modification. Further studies on transcription and mRNA maturation and export revealed a more general role for splicing speckles in RNA metabolism. Here, we discuss the functional implications of the localization of numerous proteins crucial for epigenetic regulation, chromatin organization, DNA repair and RNA modification to nuclear speckles. We highlight recent advances suggesting that NSs facilitate integrated regulation of gene expression. In addition, we consider the influence of abundant regulatory and signaling proteins, i.e. protein kinases and proteins involved in protein ubiquitination, phosphoinositide signaling and nucleoskeletal organization, on pre-mRNA synthesis and maturation. While many of these regulatory proteins act within NSs, direct evidence for mRNA metabolism events occurring in NSs is still lacking. NSs contribute to numerous human diseases, including cancers and viral infections. In addition, recent data have demonstrated close relationships between these structures and the development of neurological disorders. PMID:28977640

  10. S. 1626: This Act may be cited as the Mickey Leland Minority Economic Impact Revitalization Act. Introduced in the Senate of the United States, One Hundredth First Congress, First Session, September 14, 1989

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-01-01

    S. 1626 is a bill to establish within the Office of Minority Economic Impact of the Department of Energy (DOE) programs involving loans and grants to enhance the development and operation of minority business enterprises with respect to energy-related business, to amend the Nuclear Waste Policy Act of 1982 to permit the investment of certain funds in the Minority Bank Deposit Program of the Department of the Treasury, and for other purposes.

  11. The Lancet Countdown on health benefits from the UK Climate Change Act: a modelling study for Great Britain.

    PubMed

    Williams, Martin L; Lott, Melissa C; Kitwiroon, Nutthida; Dajnak, David; Walton, Heather; Holland, Mike; Pye, Steve; Fecht, Daniela; Toledano, Mireille B; Beevers, Sean D

    2018-05-01

    Climate change poses a dangerous and immediate threat to the health of populations in the UK and worldwide. We aimed to model different scenarios to assess the health co-benefits that result from mitigation actions. In this modelling study, we combined a detailed techno-economic energy systems model (UK TIMES), air pollutant emission inventories, a sophisticated air pollution model (Community Multi-scale Air Quality), and previously published associations between concentrations and health outcomes. We used four scenarios and focused on the air pollution implications from fine particulate matter (PM 2·5 ), nitrogen dioxide (NO 2 ) and ozone. The four scenarios were baseline, which assumed no further climate actions beyond those already achieved and did not meet the UK's Climate Change Act (at least an 80% reduction in carbon dioxide equivalent emissions by 2050 compared with 1990) target; nuclear power, which met the Climate Change Act target with a limited increase in nuclear power; low-greenhouse gas, which met the Climate Change Act target without any policy constraint on nuclear build; and a constant scenario that held 2011 air pollutant concentrations constant until 2050. We predicted the health and economic impacts from air pollution for the scenarios until 2050, and the inequalities in exposure across different socioeconomic groups. NO 2 concentrations declined leading to 4 892 000 life-years saved for the nuclear power scenario and 7 178 000 life-years saved for the low-greenhouse gas scenario from 2011 to 2154. However, the associations that we used might overestimate the effects of NO 2 itself. PM 2·5 concentrations in Great Britain are predicted to decrease between 42% and 44% by 2050 compared with 2011 in the scenarios that met the Climate Change Act targets, especially those from road traffic and off-road machinery. These reductions in PM 2·5 are tempered by a 2035 peak (and subsequent decline) in biomass (wood burning), and by a large

  12. 75 FR 64717 - Convention on Supplementary Compensation for Nuclear Damage Contingent Cost Allocation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... development of regulations pertaining to section 934, of the Energy Independence and Security Act of 2007... international supplementary fund in the event of certain nuclear incidents. The NOI provided a September 27... particular, its obligation to contribute to an international supplementary fund in the event of certain...

  13. 76 FR 67763 - Privacy Act of 1974; Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-109)] Privacy Act of 1974; Privacy Act... proposed revisions to an existing Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration is issuing public...

  14. Australian Secondary Students' Views About Global Warming: Beliefs About Actions, and Willingness to Act

    NASA Astrophysics Data System (ADS)

    Boyes, Edward; Skamp, Keith; Stanisstreet, Martin

    2009-11-01

    A 44-item questionnaire was constructed to determine secondary students’ views about how useful various specific actions might be at reducing global warming, their willingness to undertake the various actions, and the extent to which these two might be linked. Responses ( n = 500) were obtained from students in years 7 to 10 in three schools in NSW, Australia. For some pro-environmental actions, the degree to which students professed a willingness to act was greater than might be expected from the extent to which they believed the action to be useful. Such actions are those that involve minimal inconvenience such as switching off un-used electrical appliances, or those that are becoming well embedded in social practice, such as recycling. For other pro-environmental actions, the degree to which students were willing to act seemed less than might be expected, given the extent to which they believed the action to be useful. Actions concerning personal transport, such as buying smaller cars or using public rather than private transport, and obtaining more electricity from nuclear power stations, fell into this category. Here, there are disincentives to acting in a pro-environmental manner relating to personal inconvenience, or concern about nuclear power. The data were also explored to determine the strength of the relationships, for each action, between students’ professed willingness to act and their belief that an action would be effective. This suggested a measure of the potential effectiveness of education about that action. For some actions, this relationship was weak; in such cases, altering belief about the usefulness of the action might not be expected to produce major changes in behaviour. Issues concerning public transport were of this type; clearly, for issues such as these, other approaches and/or inducements may be needed to persuade people to adopt pro-environmental behaviour patterns. For other actions the relationship was stronger, so that in

  15. Tidal Disruption Events from Eccentric Nuclear Disks

    NASA Astrophysics Data System (ADS)

    Wernke, Heather N.; Madigan, Ann-Marie

    2018-04-01

    Stars that get too close to a supermassive black hole are in danger of being tidally disrupted. Stellar two-body relaxation is commonly assumed to be the main driver of these events. Recent work has shown, however, that secular gravitational torques from eccentric nuclear disks can push stars to extreme eccentricities at much higher rates than predicted by two-body relaxation. This work did not include the effects of general relativity, however, which could quench secular torques via rapid apsidal precession. Here we show that, for a star in danger of disruption, general relativity acts on a timescale of less than an orbital period. This short timescale means that general relativity does not have enough time to have a major effect on the orbit. When driven by secular torques from eccentric nuclear disks, tidal disruption event rates are not affected by general relativity.

  16. Areas for US-India civilian nuclear cooperation to prevent/mitigate radiological events.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Balachandran, Gopalan; Forden, Geoffrey Ethan

    2013-01-01

    Over the decades, India and the United States have had very little formal collaboration on nuclear issues. Partly this was because neither country needed collaboration to make progress in the nuclear field. But it was also due, in part, to the concerns both countries had about the others intentions. Now that the U.S.-India Deal on nuclear collaboration has been signed and the Hyde Act passed in the United States, it is possible to recognize that both countries can benefit from such nuclear collaboration, especially if it starts with issues important to both countries that do not touch on strategic systems.more » Fortunately, there are many noncontroversial areas for collaboration. This study, funded by the U.S. State Department, has identified a number of areas in the prevention of and response to radiological incidents where such collaboration could take place.« less

  17. Searching for nuclear export elements in hepatitis D virus RNA.

    PubMed

    Freitas, Natália; Cunha, Celso

    2013-08-12

    To search for the presence of cis elements in hepatitis D virus (HDV) genomic and antigenomic RNA capable of promoting nuclear export. We made use of a well characterized chloramphenicol acetyl-transferase reporter system based on plasmid pDM138. Twenty cDNA fragments corresponding to different HDV genomic and antigenomic RNA sequences were inserted in plasmid pDM138, and used in transfection experiments in Huh7 cells. The relative amounts of HDV RNA in nuclear and cytoplasmic fractions were then determined by real-time polymerase chain reaction and Northern blotting. The secondary structure of the RNA sequences that displayed nuclear export ability was further predicted using a web interface. Finally, the sensitivity to leptomycin B was assessed in order to investigate possible cellular pathways involved in HDV RNA nuclear export. Analysis of genomic RNA sequences did not allow identifying an unequivocal nuclear export element. However, two regions were found to promote the export of reporter mRNAs with efficiency higher than the negative controls albeit lower than the positive control. These regions correspond to nucleotides 266-489 and 584-920, respectively. In addition, when analyzing antigenomic RNA sequences a nuclear export element was found in positions 214-417. Export mediated by the nuclear export element of HDV antigenomic RNA is sensitive to leptomycin B suggesting a possible role of CRM1 in this transport pathway. A cis-acting nuclear export element is present in nucleotides 214-417 of HDV antigenomic RNA.

  18. On the unification of nuclear-structure theory: A response to Bortignon and Broglia

    NASA Astrophysics Data System (ADS)

    Cook, Norman D.

    2016-09-01

    Nuclear-structure theory is unusual among the diverse fields of quantum physics. Although it provides a coherent description of all known isotopes on the basis of a quantum-mechanical understanding of nucleon states, nevertheless, in the absence of a fundamental theory of the nuclear force acting between nucleons, the prediction of all ground-state and excited-state nuclear binding energies is inherently semi-empirical. I suggest that progress can be made by returning to the foundational work of Eugene Wigner from 1937, where the mathematical symmetries of nucleon states were first defined. Those symmetries were later successfully exploited in the development of the independent-particle model ( IPM ˜ shell model , but the geometrical implications noted by Wigner were neglected. Here I review how the quantum-mechanical, but remarkably easy-to-understand geometrical interpretation of the IPM provides constraints on the parametrization of the nuclear force. The proposed "geometrical IPM" indicates a way forward toward the unification of nuclear-structure theory that Bortignon and Broglia have called for.

  19. Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export.

    PubMed

    Behrens, Ryan T; Aligeti, Mounavya; Pocock, Ginger M; Higgins, Christina A; Sherer, Nathan M

    2017-02-01

    HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functional fluorescently tagged Rev fusion protein as a platform to study the effects of modulating Rev NES identity, number, position, or strength on Rev subcellular trafficking, viral RNA nuclear export, and infectious virion production. We found that Rev activity was remarkably tolerant of diverse NES sequences, including supraphysiological NES (SNES) peptides that otherwise arrest CRM1 transport complexes at nuclear pores. Rev's ability to tolerate a SNES was both position and multimerization dependent, an observation consistent with a model wherein Rev self-association acts to transiently mask the NES peptide(s), thereby biasing Rev's trafficking into the nucleus. Combined imaging and functional assays also indicated that NES masking underpins Rev's well-known tendency to accumulate at the nucleolus, as well as Rev's capacity to activate optimal levels of late viral gene expression. We propose that Rev multimerization and NES masking regulates Rev's trafficking to and retention within the nucleus even prior to RNA binding. HIV-1 infects more than 34 million people worldwide causing >1 million deaths per year. Infectious virion production is activated by the essential viral Rev protein that mediates nuclear export of intron-bearing late-stage viral mRNAs. Rev's shuttling into and out of the nucleus is regulated by the antagonistic activities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear export signal (NES). How Rev and related viral proteins balance strong import and export activities in order to achieve optimal levels of viral gene expression is incompletely understood. We provide evidence that multimerization provides a mechanism by which Rev transiently masks its NES peptide

  20. Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export

    PubMed Central

    Behrens, Ryan T.; Aligeti, Mounavya; Pocock, Ginger M.; Higgins, Christina A.

    2016-01-01

    ABSTRACT HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functional fluorescently tagged Rev fusion protein as a platform to study the effects of modulating Rev NES identity, number, position, or strength on Rev subcellular trafficking, viral RNA nuclear export, and infectious virion production. We found that Rev activity was remarkably tolerant of diverse NES sequences, including supraphysiological NES (SNES) peptides that otherwise arrest CRM1 transport complexes at nuclear pores. Rev's ability to tolerate a SNES was both position and multimerization dependent, an observation consistent with a model wherein Rev self-association acts to transiently mask the NES peptide(s), thereby biasing Rev's trafficking into the nucleus. Combined imaging and functional assays also indicated that NES masking underpins Rev's well-known tendency to accumulate at the nucleolus, as well as Rev's capacity to activate optimal levels of late viral gene expression. We propose that Rev multimerization and NES masking regulates Rev's trafficking to and retention within the nucleus even prior to RNA binding. IMPORTANCE HIV-1 infects more than 34 million people worldwide causing >1 million deaths per year. Infectious virion production is activated by the essential viral Rev protein that mediates nuclear export of intron-bearing late-stage viral mRNAs. Rev's shuttling into and out of the nucleus is regulated by the antagonistic activities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear export signal (NES). How Rev and related viral proteins balance strong import and export activities in order to achieve optimal levels of viral gene expression is incompletely understood. We provide evidence that multimerization provides a mechanism by which Rev transiently masks

  1. White Paper on Nuclear Data Needs and Capabilities for Basic Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Batchelder, J.; Kawano, T.; Kelley, J.

    Reliable nuclear structure and reaction data represent the fundamental building blocks of nuclear physics and astrophysics research, and are also of importance in many applications. There is a continuous demand for high-quality updates of the main nuclear physics databases via the prompt compilation and evaluation of the latest experimental and theoretical results. The nuclear physics research community benefits greatly from comprehensive, systematic and up-to-date reviews of the experimentally determined nuclear properties and observables, as well as from the ability to rapidly access these data in user-friendly forms. Such credible databases also act as a bridge between science, technology, and societymore » by making the results of basic nuclear physics research available to a broad audience of users, and hence expand the societal utilization of nuclear science. Compilation and evaluation of nuclear data has deep roots in the history of nuclear science research, as outlined in Appendix 1. They have an enormous impact on many areas of science and applications, as illustrated in Figure 2 for the Evaluated Nuclear Structure Data File (ENSDF) database. The present workshop concentrated on the needs of the basic nuclear science community for data and capabilities. The main role of this community is to generate and use data in order to understand the basic nuclear forces and interactions that are responsible for the existence and the properties of all nuclides and, as a consequence, to gain knowledge about the origins, evolution and structure of the universe. Thus, the experiments designed to measure a wealth of nuclear properties towards these fundamental scientific goals are typically performed from within this community.« less

  2. Child Welfare Act and Child Custody and Right of Access Act. Finland.

    ERIC Educational Resources Information Center

    Utriainen, Sirpa, Ed.

    The two major articles of child welfare legislation in Finland are the Child Welfare Act of 1983 and the Child Custody and Right of Access Act of 1983. These new acts are part of a reform of social legislation and services providing increased flexibility and effectiveness in protecting Finnish children's health and happiness. The Acts attach…

  3. Nuclear Regulatory Commission Issuances. Opinions and decisions of the Nuclear Regulatory Commission with selected orders: July 1, 1992--December 31, 1992, Volume 36, Pages 1--396

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-31

    This is the thirty-sixth volume of issuances (1-396) of the Nuclear Regulatory Commission and its Atomic Safety and Licensing Boards, Administrative Law Judges, and Office Directors. It covers the period from July 1, 1992-December 31, 1992. Atomic Safety and Licensing Boards are authorized by Section 191 of the Atomic Energy Act of 1954. These Boards, comprised of three members conduct adjudicatory hearings on applications to construct and operate nuclear power plants and related facilities and issue initial decisions which, subject to internal review and appellate procedures, become the final Commission action with respect to those applications. Boards are drawn frommore » the Atomic Safety and Licensing Board Panel, comprised of lawyers, nuclear physicists and engineers, environmentalists, chemists, and economists. The Atomic Energy Commission first established Licensing Boards in 1962 and the Panel in 1967.« less

  4. Nuclear Forensics: Report of the AAAS/APS Working Group

    NASA Astrophysics Data System (ADS)

    Tannenbaum, Benn

    2008-04-01

    This report was produced by a Working Group of the American Physical Society's Program on Public Affairs in conjunction with the American Association for the Advancement of Science Center for Science, Technology and Security Policy. The primary purpose of this report is to provide the Congress, U.S. government agencies and other institutions involved in nuclear forensics with a clear unclassified statement of the state of the art of nuclear forensics; an assessment of its potential for preventing and identifying unattributed nuclear attacks; and identification of the policies, resources and human talent to fulfill that potential. In the course of its work, the Working Group observed that nuclear forensics was an essential part of the overall nuclear attribution process, which aims at identifying the origin of unidentified nuclear weapon material and, in the event, an unidentified nuclear explosion. A credible nuclear attribution capability and in particular nuclear forensics capability could deter essential participants in the chain of actors needed to smuggle nuclear weapon material or carry out a nuclear terrorist act and could also encourage states to better secure such materials and weapons. The Working Group also noted that nuclear forensics result would take some time to obtain and that neither internal coordination, nor international arrangements, nor the state of qualified personnel and needed equipment were currently enough to minimize the time needed to reach reliable results in an emergency such as would be caused by a nuclear detonation or the intercept of a weapon-size quantity of material. The Working Group assesses international cooperation to be crucial for forensics to work, since the material would likely come from inadequately documented foreign sources. In addition, international participation, if properly managed, could enhance the credibility of the deterrent effect of attribution. Finally the Working Group notes that the U.S. forensics

  5. Draft environmental assessment: Lavender Canyon site, Utah. Nuclear Waste Policy Act (Section 112). [Contains glossary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1984-12-01

    In February 1983, the US Department of Energy (DOE) identified the Lavender Canyon site in Utah, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Lavender Canyon site and the eight other potentially acceptable sites h

  6. The future of high-level nuclear waste disposal, state sovereignty and the tenth amendment: Nevada v. Watkins

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swazo, S.

    The federal government`s monopoly over America`s nuclear energy production began during World War II with the birth of the Atomic Age. During the next thirty years, nuclear waste inventories increased with minor congressional concern. In the early 1970s, the need for federal legislation to address problems surrounding nuclear waste regulation, along with federal efforts to address these problems, became critical. Previous federal efforts had completely failed to address nuclear waste disposal. In 1982, Congress enacted the Nuclear Waste Policy Act (NWPA) to deal with issues of nuclear waste management and disposal, and to set an agenda for the development ofmore » two national high-level nuclear waste repositories. This article discusses the legal challenge to the NWPA in the Nevada v. Watkins case. This case illustrates the federalism problems faced by the federal government in trying to site the nation`s only high-level nuclear waste repository within a single state.« less

  7. Forgetting ACT UP

    ERIC Educational Resources Information Center

    Juhasz, Alexandra

    2012-01-01

    When ACT UP is remembered as the pinnacle of postmodern activism, other forms and forums of activism that were taking place during that time--practices that were linked, related, just modern, in dialogue or even opposition to ACT UP's "confrontational activism"--are forgotten. In its time, ACT UP was embedded in New York City, and a…

  8. DEACTIVATION AND DECOMMISSIONING ENVIRONMENTAL STRATEGY FOR THE PLUTONIUM FINISHING PLANT COMPLEX, HANFORD NUCLEAR RESERVATION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hopkins, A.M.; Heineman, R.; Norton, S.

    Maintaining compliance with environmental regulatory requirements is a significant priority in successful completion of the Plutonium Finishing Plant (PFP) Nuclear Material Stabilization (NMS) Project. To ensure regulatory compliance throughout the deactivation and decommissioning of the PFP complex, an environmental regulatory strategy was developed. The overall goal of this strategy is to comply with all applicable environmental laws and regulations and/or compliance agreements during PFP stabilization, deactivation, and eventual dismantlement. Significant environmental drivers for the PFP Nuclear Material Stabilization Project include the Tri-Party Agreement; the Resource Conservation and Recovery Act of 1976 (RCRA); the Comprehensive Environmental Response, Compensation and Liability Actmore » of 1980 (CERCLA); the National Environmental Policy Act of 1969 (NEPA); the National Historic Preservation Act (NHPA); the Clean Air Act (CAA), and the Clean Water Act (CWA). Recent TPA negotiation s with Ecology and EPA have resulted in milestones that support the use of CERCLA as the primary statutory framework for decommissioning PFP. Milestones have been negotiated to support the preparation of Engineering Evaluations/Cost Analyses for decommissioning major PFP buildings. Specifically, CERCLA EE/CA(s) are anticipated for the following scopes of work: Settling Tank 241-Z-361, the 232-Z Incinerator, , the process facilities (eg, 234-5Z, 242, 236) and the process facility support buildings. These CERCLA EE/CA(s) are for the purpose of analyzing the appropriateness of the slab-on-grade endpoint Additionally, agreement was reached on performing an evaluation of actions necessary to address below-grade structures or other structures remaining after completion of the decommissioning of PFP. Remaining CERCLA actions will be integrated with other Central Plateau activities at the Hanford site.« less

  9. Role of nuclear bodies in apoptosis signalling.

    PubMed

    Krieghoff-Henning, Eva; Hofmann, Thomas G

    2008-11-01

    Promyelocytic leukemia nuclear bodies (PML NBs) are dynamic macromolecular multiprotein complexes that recruit and release a plethora of proteins. A considerable number of PML NB components play vital roles in apoptosis, senescence regulation and tumour suppression. The molecular basis by which PML NBs control these cellular responses is still just beginning to be understood. In addition to PML itself, numerous further tumour suppressors including transcriptional regulator p53, acetyl transferase CBP (CREB binding protein) and protein kinase HIPK2 (homeodomain interacting protein kinase 2) are recruited to PML NBs in response to genotoxic stress or oncogenic transformation and drive the senescence and apoptosis response by regulating p53 activity. Moreover, in response to death-receptor activation, PML NBs may act as nuclear depots that release apoptotic factors, such as the FLASH (FLICE-associated huge) protein, to amplify the death signal. PML NBs are also associated with other nuclear domains including Cajal bodies and nucleoli and share apoptotic regulators with these domains, implying crosstalk between NBs in apoptosis regulation. In conclusion, PML NBs appear to regulate cell death decisions through different, pathway-specific molecular mechanisms.

  10. Underground nuclear power station using self-regulating heat-pipe controlled reactors

    DOEpatents

    Hampel, Viktor E.

    1989-01-01

    A nuclear reactor for generating electricity is disposed underground at the bottom of a vertical hole that can be drilled using conventional drilling technology. The primary coolant of the reactor core is the working fluid in a plurality of thermodynamically coupled heat pipes emplaced in the hole between the heat source at the bottom of the hole and heat exchange means near the surface of the earth. Additionally, the primary coolant (consisting of the working flud in the heat pipes in the reactor core) moderates neutrons and regulates their reactivity, thus keeping the power of the reactor substantially constant. At the end of its useful life, the reactor core may be abandoned in place. Isolation from the atmosphere in case of accident or for abandonment is provided by the operation of explosive closures and mechanical valves emplaced along the hole. This invention combines technology developed and tested for small, highly efficient, space-based nuclear electric power plants with the technology of fast-acting closure mechanisms developed and used for underground testing of nuclear weapons. This invention provides a nuclear power installation which is safe from the worst conceivable reactor accident, namely, the explosion of a nuclear weapon near the ground surface of a nuclear power reactor.

  11. Freedom Of Information Act

    Science.gov Websites

    Web Site Freedom of Information Act Sign In Freedom of Information Act Header Search this site ... Search Freedom of Information Act Introduction to FOIA Making A Request Points of Contact FOIA Reports Reading Room Frequently Asked Questions FOIA Links Privacy Act Requests Freedom Of Information (FOIA) &

  12. Cyber Norms for Civilian Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spirito, Christopher

    The international community agrees that the safe operation of civilian nuclear infrastructure is in every population’s best interest. One challenge each government must address is defining and agreeing to a set of acceptable norms of behavior in cyberspace as they relate to these facilities. The introduction of digital systems and networking technologies into these environments has led to the possibility that control and supporting computer systems are now accessible and exploitable, especially where interconnections to global information and communications technology (ICT) networks exist. The need for norms of behavior in cyberspace includes what is expected of system architects and cybermore » defenders as well as adversaries who should abide by rules of engagement even while conducting acts that violate national and international laws. The goal of this paper is to offer three behavioral cyber norms to improve the overall security of the ICT and Operational Technology (OT) networks and systems that underlie the operations of nuclear facilities. These norms of behavior will be specifically defined with the goals of reducing the threats associated to the theft of nuclear materials, accidental release of radiation and sabotage of nuclear processes. These norms would also include instances where an unwitting attacker or intelligence collection entity inadvertently makes their way into a nuclear facility network or system and can recognize they are in a protected zone and an approach to ensuring that these zones are not exploitable by bad actors to place their sensitive cyber effect delivery systems.« less

  13. The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc

    PubMed Central

    Warnhoff, Kurt; Roh, Hyun C.; Kocsisova, Zuzana; Tan, Chieh-Hsiang; Morrison, Andrew; Croswell, Damari; Schneider, Daniel L.; Kornfeld, Kerry

    2017-01-01

    Nuclear receptors were originally defined as endocrine sensors in humans, leading to the identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear receptors have no known ligand, suggesting new ligand classes remain to be discovered. Furthermore, nuclear receptors are encoded in the genomes of primitive organisms that lack endocrine signaling, suggesting the primordial function may have been environmental sensing. Here we describe a novel Caenorhabditis elegans nuclear receptor, HIZR-1, that is a high zinc sensor in an animal and the master regulator of high zinc homeostasis. The essential micronutrient zinc acts as a HIZR-1 ligand, and activated HIZR-1 increases transcription of genes that promote zinc efflux and storage. The results identify zinc as the first inorganic molecule to function as a physiological ligand for a nuclear receptor and direct environmental sensing as a novel function of nuclear receptors. PMID:28095401

  14. ACT Reporting Category Interpretation Guide: Version 1.0. ACT Working Paper 2016 (05)

    ERIC Educational Resources Information Center

    Powers, Sonya; Li, Dongmei; Suh, Hongwook; Harris, Deborah J.

    2016-01-01

    ACT reporting categories and ACT Readiness Ranges are new features added to the ACT score reports starting in fall 2016. For each reporting category, the number correct score, the maximum points possible, the percent correct, and the ACT Readiness Range, along with an indicator of whether the reporting category score falls within the Readiness…

  15. Speech-Act and Text-Act Theory: "Theme-ing" in Freshman Composition.

    ERIC Educational Resources Information Center

    Horner, Winifred B.

    In contrast to a speech-act theory that is limited by a simple speaker/hearer relationship, a text-act theory of written language allows for the historical or personal context of a writer and reader, both in the written work itself and in the act of reading. This theory can be applied to theme writing, essay examinations, and revision in the…

  16. Evidence against the nuclear in situ binding of arsenicals-oxidative stress theory of arsenic carcinogenesis

    EPA Science Inventory

    A large amount of evidence suggests that arsenicals act via oxidative stress in causing cancer in humans and experimental animals. It is possible that arsenicals could bind in situ close to nuclear DNA followed by Haber-Weiss type oxidative DNA damage. Therefore, we tested this...

  17. The role of the health physicist in nuclear security.

    PubMed

    Waller, Edward J; van Maanen, Jim

    2015-04-01

    Health physics is a recognized safety function in the holistic context of the protection of workers, members of the public, and the environment against the hazardous effects of ionizing radiation, often generically designated as radiation protection. The role of the health physicist as protector dates back to the Manhattan Project. Nuclear security is the prevention and detection of, and response to, criminal or intentional unauthorized acts involving or directed at nuclear material, other radioactive material, associated facilities, or associated activities. Its importance has become more visible and pronounced in the post 9/11 environment, and it has a shared purpose with health physics in the context of protection of workers, members of the public, and the environment. However, the duties and responsibilities of the health physicist in the nuclear security domain are neither clearly defined nor recognized, while a fundamental understanding of nuclear phenomena in general, nuclear or other radioactive material specifically, and the potential hazards related to them is required for threat assessment, protection, and risk management. Furthermore, given the unique skills and attributes of professional health physicists, it is argued that the role of the health physicist should encompass all aspects of nuclear security, ranging from input in the development to implementation and execution of an efficient and effective nuclear security regime. As such, health physicists should transcend their current typical role as consultants in nuclear security issues and become fully integrated and recognized experts in the nuclear security domain and decision making process. Issues regarding the security clearances of health physics personnel and the possibility of insider threats must be addressed in the same manner as for other trusted individuals; however, the net gain from recognizing and integrating health physics expertise in all levels of a nuclear security regime far

  18. The Role of the Health Physicist in Nuclear Security

    PubMed Central

    Waller, Edward J.; van Maanen, Jim

    2015-01-01

    Abstract Health physics is a recognized safety function in the holistic context of the protection of workers, members of the public, and the environment against the hazardous effects of ionizing radiation, often generically designated as radiation protection. The role of the health physicist as protector dates back to the Manhattan Project. Nuclear security is the prevention and detection of, and response to, criminal or intentional unauthorized acts involving or directed at nuclear material, other radioactive material, associated facilities, or associated activities. Its importance has become more visible and pronounced in the post 9/11 environment, and it has a shared purpose with health physics in the context of protection of workers, members of the public, and the environment. However, the duties and responsibilities of the health physicist in the nuclear security domain are neither clearly defined nor recognized, while a fundamental understanding of nuclear phenomena in general, nuclear or other radioactive material specifically, and the potential hazards related to them is required for threat assessment, protection, and risk management. Furthermore, given the unique skills and attributes of professional health physicists, it is argued that the role of the health physicist should encompass all aspects of nuclear security, ranging from input in the development to implementation and execution of an efficient and effective nuclear security regime. As such, health physicists should transcend their current typical role as consultants in nuclear security issues and become fully integrated and recognized experts in the nuclear security domain and decision making process. Issues regarding the security clearances of health physics personnel and the possibility of insider threats must be addressed in the same manner as for other trusted individuals; however, the net gain from recognizing and integrating health physics expertise in all levels of a nuclear security regime

  19. International training course on nuclear materials accountability for safeguards purposes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1980-12-01

    The two volumes of this report incorporate all lectures and presentations at the International Training Course on Nuclear Materials Accountability and Control for Safeguards Purposes, held May 27-June 6, 1980, at the Bishop's Lodge near Santa Fe, New Mexico. The course, authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, was developed to provide practical training in the design, implementation, and operation of a National system of nuclear materials accountability and control that satisfies both National and IAEA International safeguards objectives. Volume I, covering the firstmore » week of the course, presents the background, requirements, and general features of material accounting and control in modern safeguard systems. Volume II, covering the second week of the course, provides more detailed information on measurement methods and instruments, practical experience at power reactor and research reactor facilities, and examples of operating state systems of accountability and control.« less

  20. Nuclear spin relaxation of methane in solid xenon

    NASA Astrophysics Data System (ADS)

    Sugimoto, Takeru; Arakawa, Ichiro; Yamakawa, Koichiro

    2018-03-01

    Nuclear spin relaxation of methane in solid xenon has been studied by infrared spectroscopy. From the analysis of the temporal changes of the rovibrational peaks, the rates of the nuclear spin relaxation of I = 2 ← 1 correlated to the rotational relaxation of J = 0 ← 1 were obtained at temperatures of 5.1-11.5 K. On the basis of the temperature dependence of the relaxation rate, the activation energy of the indirect two-phonon process was determined to be 50 ± 6 K, which is in good agreement with the rotational transition energies of J = 2 ← 1 and J = 3 ← 1. Taking into account this result and the spin degeneracy, we argue that the lowest J = 3 level in which the I = 1 and I = 2 states are degenerate acts as the intermediate point of the indirect process.

  1. 76 FR 64114 - Privacy Act of 1974; Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ....C. 2473 (2003); Federal Records Act, 44 U.S.C. 3101 (2003); Chief Financial Officers Act of 1990 205.... ADDRESSES: Patti F. Stockman, Privacy Act Officer, Office of the Chief Information Officer, National... Information Officer. NASA 10CFMR SYSTEM NAME: Core Financial Management Records. SECURITY CLASSIFICATION: This...

  2. The Library Systems Act and Rules for Administering the Library Systems Act.

    ERIC Educational Resources Information Center

    Texas State Library, Austin. Library Development Div.

    This document contains the Texas Library Systems Act and rules for administering the Library Systems Act. Specifically, it includes the following documents: Texas Library Systems Act; Summary of Codes;Texas Administrative Code: Service Complaints and Protest Procedure; Criteria For Texas Library System Membership; and Certification Requirements…

  3. The dermatology acting internship.

    PubMed

    Stephens, John B; Raimer, Sharon S; Wagner, Richard F

    2011-07-15

    Acting internships are an important component of modern day medical school curriculum. Several specialties outside of internal medicine now offer acting internship experiences to fourth year medical students. We have found that a dermatology acting internship is a valuable experience for fourth year medical students who are interested in pursuing a residency in dermatology. Our experience with the dermatology acting internship over the 2010-2011 academic year is described.

  4. CBP70, a glycosylated nuclear lectin.

    PubMed

    Rousseau, C; Felin, M; Doyennette-Moyne, M A; Sève, A P

    1997-09-01

    Some years ago, a lectin designated CBP70 that recognized glucose (Glc) but had a stronger affinity for N-acetylglucosamine (GlcNAc), was first isolated from HL60 cell nuclei. Recently, a cytoplasmic form of this lectin was described, and one 82 kDa nuclear ligand was characterized for the nuclear CBP70. In the present study, the use of Pronase digestion and the trifluoromethanesulphonic acid (TFMS) procedure strongly suggest that the nuclear and the cytoplasmic CBP70 have a same 23 kDa polypeptide backbone and, consequently, could be the same protein. In order to know the protein better and to obtain the best recombinant possible in the future, the post-translational modification of the nuclear and cytoplasmic CBP70 was analyzed in terms of glycosylation. Severals lines of evidence indicate that both forms of CBP70 are N- and O-glycosylated. Surprisingly, this glycosylation pattern differs between the two forms, as revealed by beta-elimination, hydrazinolysis, peptide-N-glycosydase F (PNGase F), and TFMS reactions. The two preparations were analyzed by affinity chromatography on immobilized lectins [Ricinus communis-l agglutinin (RCA-I), Arachis hypogaea agglutinin (PNA), Galanthus nivalis agglutinin (GNA), and wheat germ agglutinin (WGA)] and by lectin-blotting analysis Sambucus nigra agglutinin (SNA), Maackia amurensis agglutinin (MAA), Lotus tetragonolobus (Lotus), succinylated-WGA, and Psathyrella velutina agglutinin (PVA)]. Both forms of CBP70 have the following sugar moities: terminal beta Gal residues, Gal beta 1-3 GalNAc, Man alpha 1-3 Man, sialic acid alpha 2-6 linked to Gal or GalNAc; and sialic acid alpha 2-3 linked to Gal. However, only nuclear CBP70 have terminal GlcNAc and alpha-L-fucose residues. All these data are consistent with the fact that different glycosylation pattern found for each form of CBP70 might act as a complementary signal for cellular targeting.

  5. 46 CFR 540.3 - Proof of financial responsibility, when required.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Proof of financial responsibility, when required. 540.3... COMMERCE PASSENGER VESSEL FINANCIAL RESPONSIBILITY Proof of Financial Responsibility, Bonding and Certification of Financial Responsibility for Indemnification of Passengers for Nonperformance of Transportation...

  6. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality of...

  7. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality of...

  8. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality of...

  9. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality of...

  10. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality of...

  11. An underground nuclear power station using self-regulating heat-pipe controlled reactors

    DOEpatents

    Hampel, V.E.

    1988-05-17

    A nuclear reactor for generating electricity is disposed underground at the bottom of a vertical hole that can be drilled using conventional drilling technology. The primary coolant of the reactor core is the working fluid in a plurality of thermodynamically coupled heat pipes emplaced in the hole between the heat source at the bottom of the hole and heat exchange means near the surface of the earth. Additionally, the primary coolant (consisting of the working fluid in the heat pipes in the reactor core) moderates neutrons and regulates their reactivity, thus keeping the power of the reactor substantially constant. At the end of its useful life, the reactor core may be abandoned in place. Isolation from the atmosphere in case of accident or for abandonment is provided by the operation of explosive closures and mechanical valves emplaced along the hole. This invention combines technology developed and tested for small, highly efficient, space-based nuclear electric power plants with the technology of fast- acting closure mechanisms developed and used for underground testing of nuclear weapons. This invention provides a nuclear power installation which is safe from the worst conceivable reactor accident, namely, the explosion of a nuclear weapon near the ground surface of a nuclear power reactor. 5 figs.

  12. ACT Average Composite by State: 2000 ACT-Tested Graduates.

    ERIC Educational Resources Information Center

    American Coll. Testing Program, Iowa City, IA.

    This table contains average composite scores by state for high school graduates who took the ACT Assessment in 2000. For each state the percentage of graduates taking the ACT Assessment and the average composite score are given, with the same information for those who completed the recommended core curriculum and those who did not, as well as for…

  13. Seal welded cast iron nuclear waste container

    DOEpatents

    Filippi, Arthur M.; Sprecace, Richard P.

    1987-01-01

    This invention identifies methods and articles designed to circumvent metallurgical problems associated with hermetically closing an all cast iron nuclear waste package by welding. It involves welding nickel-carbon alloy inserts which are bonded to the mating plug and main body components of the package. The welding inserts might be bonded in place during casting of the package components. When the waste package closure weld is made, the most severe thermal effects of the process are restricted to the nickel-carbon insert material which is far better able to accommodate them than is cast iron. Use of nickel-carbon weld inserts should eliminate any need for pre-weld and post-weld heat treatments which are a problem to apply to nuclear waste packages. Although the waste package closure weld approach described results in a dissimilar metal combination, the relative surface area of nickel-to-iron, their electrochemical relationship, and the presence of graphite in both materials will act to prevent any galvanic corrosion problem.

  14. Lipid partitioning at the nuclear envelope controls membrane biogenesis

    PubMed Central

    Barbosa, Antonio Daniel; Sembongi, Hiroshi; Su, Wen-Min; Abreu, Susana; Reggiori, Fulvio; Carman, George M.; Siniossoglou, Symeon

    2015-01-01

    Partitioning of lipid precursors between membranes and storage is crucial for cell growth, and its disruption underlies pathologies such as cancer, obesity, and type 2 diabetes. However, the mechanisms and signals that regulate this process are largely unknown. In yeast, lipid precursors are mainly used for phospholipid synthesis in nutrient-rich conditions in order to sustain rapid proliferation but are redirected to triacylglycerol (TAG) stored in lipid droplets during starvation. Here we investigate how cells reprogram lipid metabolism in the endoplasmic reticulum. We show that the conserved phosphatidate (PA) phosphatase Pah1, which generates diacylglycerol from PA, targets a nuclear membrane subdomain that is in contact with growing lipid droplets and mediates TAG synthesis. We find that cytosol acidification activates the master regulator of Pah1, the Nem1-Spo7 complex, thus linking Pah1 activity to cellular metabolic status. In the absence of TAG storage capacity, Pah1 still binds the nuclear membrane, but lipid precursors are redirected toward phospholipids, resulting in nuclear deformation and a proliferation of endoplasmic reticulum membrane. We propose that, in response to growth signals, activation of Pah1 at the nuclear envelope acts as a switch to control the balance between membrane biogenesis and lipid storage. PMID:26269581

  15. 7 CFR 63.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) NATIONAL SHEEP INDUSTRY IMPROVEMENT CENTER... Development Act, 7 U.S.C. 2008j, as amended by section 11009 of the Food, Conservation, and Energy Act of 2008...

  16. The road to Yucca Mountain—Evolution of nuclear waste disposal in the United States

    USGS Publications Warehouse

    Stuckless, John S.; Levich, Robert A.

    2016-01-01

    The generation of electricity by nuclear power and the manufacturing of atomic weapons have created a large amount of spent nuclear fuel and high-level radioactive waste. There is a world-wide consensus that the best way to protect mankind and the environment is to dispose of this waste in a deep geologic repository. Initial efforts focused on salt as the best medium for disposal, but the heat generated by the radioactive waste led many earth scientists to examine other rock types. In 1976, the director of the U.S. Geological Survey (USGS) wrote to the U.S. Energy Research and Development Administration (ERDA), predecessor agency of the U.S. Department of Energy (DOE), suggesting that there were several favorable environments at the Nevada Test Site (NTS), and that the USGS already had extensive background information on the NTS. Later, in a series of communications and one publication, the USGS espoused the favorability of the thick unsaturated zone. After the passage of the Nuclear Waste Policy Act (1982), the DOE compiled a list of nine favorable sites and settled on three to be characterized. In 1987, as the costs of characterizing three sites ballooned, Congress amended the Nuclear Waste Policy Act directing the DOE to focus only on Yucca Mountain in Nevada, with the proviso that if anything unfavorable was discovered, work would stop immediately. The U.S. DOE, the U.S. DOE national laboratories, and the USGS developed more than 100 detailed plans to study various earth-science aspects of Yucca Mountain and the surrounding area, as well as materials studies and engineering projects needed for a mined geologic repository. The work, which cost more than 10 billion dollars and required hundreds of man-years of work, culminated in a license application submitted to the U.S. Nuclear Regulatory Commission (NRC) in 2008.

  17. NUCLEAR INCIDENT CAPABILITIES, KNOWLEDGE & ENABLER LEVERAGING

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kinney, J.; Newman, J.; Goodwyn, A.

    2011-04-18

    The detonation of a 10 Kiloton Improvised Nuclear Device (IND) is a serious scenario that the United States must be prepared to address. The likelihood of a single nuclear bomb exploding in a single city is greater today than at the height of the Cold War. Layered defenses against domestic nuclear terrorism indicate that our government continues to view the threat as credible. The risk of such an event is further evidenced by terrorists desire to acquire nuclear weapons. The act of nuclear terrorism, particularly an act directed against a large population center in the United States, will overwhelm themore » capabilities of many local and state governments to respond, and will seriously challenge existing federal response capabilities. A 10 Kiloton IND detonation would cause total infrastructure damage in a 3-mile radius and levels of radiation spanning out 3,000 square miles. In a densely populated urban area, the anticipated casualties would be in excess of several hundred thousand. Although there would be enormous loss of life, housing and infrastructure, an IND detonation is a recoverable event. We can reduce the risk of these high-consequence, nontraditional threats by enhancing our nuclear detection architecture and establishing well planned and rehearsed plans for coordinated response. It is also important for us to identify new and improved ways to foster collaboration regarding the response to the IND threat to ensure the demand and density of expertise required for such an event is postured and prepared to mobilize, integrate, and support a myriad of anticipated challenges. We must be prepared to manage the consequences of such an event in a deliberate manner and get beyond notions of total devastation by adopting planning assumptions around survivability and resiliency. Planning for such a scenario needs to be decisive in determining a response based on competencies and desired outcomes. It is time to synthesize known threats and plausible consequences

  18. Human cytomegalovirus DNA polymerase catalytic subunit pUL54 possesses independently acting nuclear localization and ppUL44 binding motifs.

    PubMed

    Alvisi, Gualtiero; Ripalti, Alessandro; Ngankeu, Apollinaire; Giannandrea, Maila; Caraffi, Stefano G; Dias, Manisha M; Jans, David A

    2006-10-01

    The catalytic subunit of human cytomegalovirus (HCMV) DNA polymerase pUL54 is a 1242-amino-acid protein, whose function, stimulated by the processivity factor, phosphoprotein UL44 (ppUL44), is essential for viral replication. The C-terminal residues (amino acids 1220-1242) of pUL54 have been reported to be sufficient for ppUL44 binding in vitro. Although believed to be important for functioning in the nuclei of infected cells, no data are available on either the interaction of pUL54 with ppUL44 in living mammalian cells or the mechanism of pUL54 nuclear transport and its relationship with that of ppUL44. The present study examines for the first time the nuclear import pathway of pUL54 and its interaction with ppUL44 using dual color, quantitative confocal laser scanning microscopy on live transfected cells and quantitative gel mobility shift assays. We showed that of two nuclear localization signals (NLSs) located at amino acids 1153-1159 (NLSA) and 1222-1227 (NLSB), NLSA is sufficient to confer nuclear localization on green fluorescent protein (GFP) by mediating interaction with importin alpha/beta. We also showed that pUL54 residues 1213-1242 are sufficient to confer ppUL44 binding abilities on GFP and that pUL54 and ppUL44 can be transported to the nucleus as a complex. Our work thus identified distinct sites within the HCMV DNA polymerase, which represent potential therapeutic targets and establishes the molecular basis of UL54 nuclear import.

  19. Ion-induced nuclear radiotherapy

    DOEpatents

    Horn, K.M.; Doyle, B.L.

    1996-08-20

    Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue. 25 figs.

  20. Ion-induced nuclear radiotherapy

    DOEpatents

    Horn, Kevin M.; Doyle, Barney L.

    1996-01-01

    Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue.

  1. ACT-R Electronic Bookshelf: An Adaptive System To Support Learning ACT-R on the Web.

    ERIC Educational Resources Information Center

    Brusilovsky, Peter; Anderson, John

    This paper describes the electronic ACT-R Bookshelf, a system which supports learning ACT-R, a well-known theory in the field of cognitive psychology, over the World Wide Web. ACT-R Bookshelf is a collection of electronic books on various aspects of ACT-R. The primary role of ACT-R Bookshelf is to serve as a 24-hour information resource for…

  2. ACTS data center

    NASA Technical Reports Server (NTRS)

    Syed, Ali; Vogel, Wolfhard J.

    1993-01-01

    Viewgraphs on ACTS Data Center status report are included. Topics covered include: ACTS Data Center Functions; data flow overview; PPD flow; RAW data flow; data compression; PPD distribution; RAW Data Archival; PPD Audit; and data analysis.

  3. Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access.

    PubMed

    Uzer, Gunes; Bas, Guniz; Sen, Buer; Xie, Zhihui; Birks, Scott; Olcum, Melis; McGrath, Cody; Styner, Maya; Rubin, Janet

    2018-06-06

    βcatenin acts as a primary intracellular signal transducer for mechanical and Wnt signaling pathways to control cell function and fate. Regulation of βcatenin in the cytoplasm has been well studied but βcatenin nuclear trafficking and function remains unclear. In a previous study we showed that, in mesenchymal stem cells (MSC), mechanical blockade of adipogenesis relied on inhibition of βcatenin destruction complex element GSK3β (glycogen synthase kinase 3β) to increase nuclear βcatenin as well as the function of Linker of Cytoskeleton and Nucleoskeleton (LINC) complexes, suggesting that these two mechanisms may be linked. Here we show that shortly after inactivation of GSK3β due to either low intensity vibration (LIV), substrate strain or pharmacologic inhibition, βcatenin associates with the nucleoskeleton, defined as the insoluble nuclear fraction that provides structure to the integrated nuclear envelope, nuclear lamina and chromatin. Co-depleting LINC elements Sun-1 and Sun-2 interfered with both nucleoskeletal association and nuclear entry of βcatenin, resulting in decreased nuclear βcatenin levels. Our findings reveal that the insoluble structural nucleoskeleton actively participates in βcatenin dynamics. As the cytoskeleton transmits applied mechanical force to the nuclear surface to influence the nucleoskeleton and its LINC mediated interaction, our results suggest a pathway by which LINC mediated connectivity may play a role in signaling pathways that depend on nuclear access of βcatenin. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. 46 CFR 540.7 - Evidence of financial responsibility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Evidence of financial responsibility. 540.7 Section 540... PASSENGER VESSEL FINANCIAL RESPONSIBILITY Proof of Financial Responsibility, Bonding and Certification of Financial Responsibility for Indemnification of Passengers for Nonperformance of Transportation § 540.7...

  5. 5 CFR 911.102 - General definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false General definitions. 911.102 Section 911.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.102 General definitions. In...

  6. 5 CFR 911.102 - General definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false General definitions. 911.102 Section 911.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.102 General definitions. In...

  7. 5 CFR 911.102 - General definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false General definitions. 911.102 Section 911.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.102 General definitions. In...

  8. 5 CFR 911.102 - General definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false General definitions. 911.102 Section 911.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.102 General definitions. In...

  9. 5 CFR 911.102 - General definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false General definitions. 911.102 Section 911.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.102 General definitions. In...

  10. Privacy Act Statement

    EPA Pesticide Factsheets

    Any information you provide to the Environmental Protection Agency’s (EPA) Suspension and Debarment Program will be governed by the Privacy Act and will be included in the EPA Debarment and Suspension Files, a Privacy Act system of records.

  11. Recovery Act Milestones

    ScienceCinema

    Rogers, Matt

    2018-05-11

    Every 100 days, the Department of Energy is held accountable for a progress report on the American Recovery and Reinvestment Act. Update at 200 days, hosted by Matt Rogers, Senior Advisor to Secretary Steven Chu for Recovery Act Implementation.

  12. Recovery Act Milestones

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rogers, Matt

    2009-01-01

    Every 100 days, the Department of Energy is held accountable for a progress report on the American Recovery and Reinvestment Act. Update at 200 days, hosted by Matt Rogers, Senior Advisor to Secretary Steven Chu for Recovery Act Implementation.

  13. Orphan Nuclear Receptors as Targets for Drug Development

    PubMed Central

    Mukherjee, Subhajit

    2012-01-01

    Orphan nuclear receptors regulate diverse biological processes. These important molecules are ligand-activated transcription factors that act as natural sensors for a wide range of steroid hormones and xenobiotic ligands. Because of their importance in regulating various novel signaling pathways, recent research has focused on identifying xenobiotics targeting these receptors for the treatment of multiple human diseases. In this review, we will highlight these receptors in several physiologic and pathophysiologic actions and demonstrate how their functions can be exploited for the successful development of newer drugs. PMID:20372994

  14. The British Climate Change Act: a critical evaluation and proposed alternative approach

    NASA Astrophysics Data System (ADS)

    Pielke, Roger A., Jr.

    2009-04-01

    This paper evaluates the United Kingdom's Climate Change Act of 2008 in terms of the implied rates of decarbonization of the UK economy for a short-term and a long-term target established in law. The paper uses the Kaya identity to structure the evaluation, employing both a bottom up approach (based on projections of future UK population, economic growth, and technology) and a top down approach (deriving implied rates of decarbonization consistent with the targets and various rates of projected economic growth). Both approaches indicate that the UK economy would have to achieve annual rates of decarbonization in excess of 4 or 5%. To place these numbers in context, the UK would have to achieve the 2006 carbon efficiency of France by about 2015, a level of effort comparable to the building of about 30 new nuclear power plants, displacing an equivalent amount of fossil energy. The paper argues that the magnitude of the task implied by the UK Climate Change Act strongly suggests that it is on course to fail, and discusses implications.

  15. Chemical nuclear polarization effects in photoreactions of 1,4-diazabicyclo[2.2.2]octane with carbonyl-containing compounds

    NASA Astrophysics Data System (ADS)

    Porkhun, V. I.; Rakhimov, A. I.

    2012-11-01

    Elementary acts of the photoreaction of diamine with 2,6-diphenyl- p-benzoquinone are determined from the effects of chemical nuclear polarization effects. Hydrogen atom transfer is shown to occur in two stages with the participation of a radical ion pair.

  16. Russia`s Great Game in a nuclear South Asia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pilat, J.F.; Taylor, T.T.

    1998-12-31

    Lost in the noise of Pakistan`s nuclear weapon tests in the western Baluchistan desert on 28 and 30 May was a surprising diplomatic move by Russia. On 23 May, Russia became the first state to express its willingness to recognize India as a nuclear-weapon state, provided that India commits itself to the international nonproliferation regime. Russia`s Ambassador to India, Albert Chernyshev, stated in the days after the Indian but before the Pakistani nuclear tests that ``India proclaimed itself a nuclear weapons power. One now hopes that India will behave as a nuclear weapons power by acting responsibly. Every nuclear weaponsmore » state has some rights. But for getting recognition it must have some obligations. Once it is ready to show these obligations by joining the nonproliferation regime, its recognition as a nuclear weapons power will follow.`` Russia`s Great Game in South Asia in pursuit of short-term economic and other interests appears to be a serious obstacle on the path to dealing effectively with the South Asian nuclear crisis. Grave damage to security, stability and nonproliferation has already resulted from India`s and Pakistan`s actions, but the situation does not have to spiral out of control. It is imperative that the international community respond appropriately to this challenge. The international community is at a crossroads and Russia`s actions will be critical. Will it be willing to go beyond the narrow economic and political calculations reflected in its diplomatic posturing, and take actions that will serve its long-term interests by bridging differences with other great powers in order to demonstrate to India that it has not chosen the right path. If Russia decides it can gain from India`s current, perilous path and blocks or otherwise frustrates appropriate responses, the nuclear danger on the subcontinent will escalate and the global regimes to promote nonproliferation and to ban testing will be seriously, perhaps fatally, weakened with

  17. Magnetic Imaging: a New Tool for UK National Nuclear Security

    NASA Astrophysics Data System (ADS)

    Darrer, Brendan J.; Watson, Joe C.; Bartlett, Paul; Renzoni, Ferruccio

    2015-01-01

    Combating illicit trafficking of Special Nuclear Material may require the ability to image through electromagnetic shields. This is the case when the trafficking involves cargo containers. Thus, suitable detection techniques are required to penetrate a ferromagnetic enclosure. The present study considers techniques that employ an electromagnetic based principle of detection. It is generally assumed that a ferromagnetic metallic enclosure will effectively act as a Faraday cage to electromagnetic radiation and therefore screen any form of interrogating electromagnetic radiation from penetrating, thus denying the detection of any eventual hidden material. In contrast, we demonstrate that it is actually possible to capture magnetic images of a conductive object through a set of metallic ferromagnetic enclosures. This validates electromagnetic interrogation techniques as a potential detection tool for National Nuclear Security applications.

  18. Magnetic Imaging: a New Tool for UK National Nuclear Security

    PubMed Central

    Darrer, Brendan J.; Watson, Joe C.; Bartlett, Paul; Renzoni, Ferruccio

    2015-01-01

    Combating illicit trafficking of Special Nuclear Material may require the ability to image through electromagnetic shields. This is the case when the trafficking involves cargo containers. Thus, suitable detection techniques are required to penetrate a ferromagnetic enclosure. The present study considers techniques that employ an electromagnetic based principle of detection. It is generally assumed that a ferromagnetic metallic enclosure will effectively act as a Faraday cage to electromagnetic radiation and therefore screen any form of interrogating electromagnetic radiation from penetrating, thus denying the detection of any eventual hidden material. In contrast, we demonstrate that it is actually possible to capture magnetic images of a conductive object through a set of metallic ferromagnetic enclosures. This validates electromagnetic interrogation techniques as a potential detection tool for National Nuclear Security applications. PMID:25608957

  19. Magnetic imaging: a new tool for UK national nuclear security.

    PubMed

    Darrer, Brendan J; Watson, Joe C; Bartlett, Paul; Renzoni, Ferruccio

    2015-01-22

    Combating illicit trafficking of Special Nuclear Material may require the ability to image through electromagnetic shields. This is the case when the trafficking involves cargo containers. Thus, suitable detection techniques are required to penetrate a ferromagnetic enclosure. The present study considers techniques that employ an electromagnetic based principle of detection. It is generally assumed that a ferromagnetic metallic enclosure will effectively act as a Faraday cage to electromagnetic radiation and therefore screen any form of interrogating electromagnetic radiation from penetrating, thus denying the detection of any eventual hidden material. In contrast, we demonstrate that it is actually possible to capture magnetic images of a conductive object through a set of metallic ferromagnetic enclosures. This validates electromagnetic interrogation techniques as a potential detection tool for National Nuclear Security applications.

  20. 7 CFR 1260.128 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BEEF PROMOTION AND RESEARCH Beef Promotion and Research Order Definitions § 1260.128 Act. Act means the Beef Promotion and Research Act of 1985, Title XVI, Subtitle A of the Food Security Act of 1985, Pub. L. 99-198 and any amendments thereto. ...

  1. Postage for the messenger: Designating routes for Nuclear mRNA Export

    PubMed Central

    Natalizio, Barbara J.; Wente, Susan R.

    2013-01-01

    Transcription of messenger(m) RNA occurs in the nucleus, making the translocation of mRNA across the nuclear envelope (NE) boundary a critical determinant of proper gene expression and cell survival. A major mRNA export route occurs via the NXF1-dependent pathway through the nuclear pore complexes (NPCs) embedded in the NE. However, recent findings have discovered new evidence supporting the existence of multiple mechanisms for crossing the NE, including both NPC-mediated and NE budding-mediated pathways. An analysis of the trans-acting factors and cis components that define these pathways reveals shared elements as well as mechanistic differences. We review here the current understanding of the mechanisms that characterize each pathway and highlight the determinants that influence mRNA transport fate. PMID:23583578

  2. Development and characterization of a long-acting nanoformulated abacavir prodrug.

    PubMed

    Singh, Dhirender; McMillan, JoEllyn; Hilaire, James; Gautam, Nagsen; Palandri, Diana; Alnouti, Yazen; Gendelman, Howard E; Edagwa, Benson

    2016-08-01

    A myristoylated abacavir (ABC) prodrug was synthesized to extend drug half-life and bioavailability. Myristoylated ABC (MABC) was made by esterifying myristic acid to the drug's 5-hydroxy-cyclopentene group. Chemical composition, antiretroviral activity, cell uptake and retention and cellular trafficking of free MABC and poloxamer nanoformulations of MABC were assessed by proton nuclear magnetic resonance and tested in human monocyte-derived macrophages. Pharmacokinetics of ABC and nanoformulated MABC were evaluated after intramuscular injection into mice. MABC antiretroviral activity in monocyte-derived macrophages was comparable to native drug. Encasement of MABC into poloxamer nanoparticles extended drug bioavailability for 2 weeks. MABC synthesis and encasement in polymeric nanoformulations improved intracellular drug accumulation and demonstrate translational potential as part of a long-acting antiretroviral regimen.

  3. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums in...

  4. Forty-Year Anniversary of Louisiana's Medical Malpractice Act, Act 817 of 1975.

    PubMed

    Palmisano, Donald J

    2015-01-01

    Here we are at the 40th anniversary of the passage of the 1975 Medical Malpractice Act, Act 817.2 How time flies! Act 817 of 1975 lives and the Louisiana State Supreme Court has ruled the current law, a total cap on all damages with its 1984 amendment for unlimited future medical payments as incurred (La. Act 435 of 19843), constitutional in the Butler case previously cited in the 20-year anniversary article (reprinted in this issue of the Journal). Louisiana's law was voted into law prior to California's famous medical liability law.4 For another great triumph, see Texas and its success in 2003.5 Three different laws; three proven long-term successes.

  5. The C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT Domain

    PubMed Central

    Yang, Yinshan; Labesse, Gilles; Carrère-Kremer, Séverine; Esteves, Kevin; Kremer, Laurent

    2012-01-01

    MgtC is a virulence factor of unknown function important for survival inside macrophages in several intracellular bacterial pathogens, including Mycobacterium tuberculosis. It is also involved in adaptation to Mg2+ deprivation, but previous work suggested that MgtC is not a Mg2+ transporter. In this study, we demonstrated that the amount of the M. tuberculosis MgtC protein is not significantly increased by Mg2+ deprivation. Members of the MgtC protein family share a conserved membrane N-terminal domain and a more divergent cytoplasmic C-terminal domain. To get insights into MgtC functional and structural organization, we have determined the nuclear magnetic resonance (NMR) structure of the C-terminal domain of M. tuberculosis MgtC. This structure is not affected by the Mg2+ concentration, indicating that it does not bind Mg2+. The structure of the C-terminal domain forms a βαββαβ fold found in small molecule binding domains called ACT domains. However, the M. tuberculosis MgtC ACT domain differs from canonical ACT domains because it appears to lack the ability to dimerize and to bind small molecules. We have shown, using a bacterial two-hybrid system, that the M. tuberculosis MgtC protein can dimerize and that the C-terminal domain somehow facilitates this dimerization. Taken together, these results indicate that M. tuberculosis MgtC does not have an intrinsic function related to Mg2+ uptake or binding but could act as a regulatory factor based on protein-protein interaction that could be facilitated by its ACT domain. PMID:22984256

  6. Defense Infrastructure: Greater Management Emphasis Needed to Increase the Services’ Use of Expanded Leasing Authority

    DTIC Science & Technology

    2002-06-01

    other issues. In addition, a DOD official stated that the services could capitalize on their historic property by marketing the property to the film ... industry , which could generate substantial revenue. The Department’s report and service officials stated that environmental indemnification (i.e., to

  7. 78 FR 80367 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-72; Introduction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...-ended, unrestricted indemnification clause. This rule clarified for the public that an End User License... and nonbinding against the Government and Government- authorized end-users. The rule contained a new... application of the World Trade Organization Government Procurement Agreement and the Free Trade Agreements as...

  8. 5 CFR 911.101 - Scope and purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Scope and purpose. 911.101 Section 911.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.101 Scope and purpose. (a...

  9. 5 CFR 911.101 - Scope and purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Scope and purpose. 911.101 Section 911.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.101 Scope and purpose. (a...

  10. 5 CFR 911.101 - Scope and purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Scope and purpose. 911.101 Section 911.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.101 Scope and purpose. (a...

  11. 5 CFR 911.101 - Scope and purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Scope and purpose. 911.101 Section 911.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.101 Scope and purpose. (a...

  12. 5 CFR 911.101 - Scope and purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Scope and purpose. 911.101 Section 911.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 911.101 Scope and purpose. (a...

  13. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  14. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  15. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  16. 17 CFR 230.484 - Undertaking required in certain registration statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... statement is prepared on a form available solely to investment companies registered under the investment... and an undertaking in substantially the following form: Insofar as indemnification for liability..., suit or proceeding) is asserted by such director, officer or controlling person in connection with the...

  17. 36 CFR 228.110 - Indemnification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... United States for: (a) Injury, loss or damage, including fire suppression costs, which the United States incurs as a result of the operations; and (b) Payments made by the United States in satisfaction of claims, demands or judgments for an injury, loss or damage, including fire suppression costs, which...

  18. Overview of U.S. nuclear launch safety approval process, supporting launch vehicle databook and probabilistic risk assessment methods

    NASA Technical Reports Server (NTRS)

    Reinhart, L. E.

    2001-01-01

    This paper provides an overview of the U.S. space nuclear power system launch approval process as defined by the two separate requirements of the National Environmental Policy Act (NEPA) and Presidential Directive/National Security Council Memorandum No. 25 (PD/NSC-25).

  19. 12 CFR 741.214 - Report of crime or catastrophic act and Bank Secrecy Act compliance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Report of crime or catastrophic act and Bank Secrecy Act compliance. 741.214 Section 741.214 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... Unions § 741.214 Report of crime or catastrophic act and Bank Secrecy Act compliance. Any credit union...

  20. Reducing Risk for the Next Generation Nuclear Plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John M. Beck II; Harold J. Heydt; Emmanuel O. Opare

    2010-07-01

    The Next Generation Nuclear Plant (NGNP) Project, managed by the Idaho National Laboratory (INL), is directed by the Energy Policy Act of 2005, to research, develop, design, construct, and operate a prototype forth generation nuclear reactor to meet the needs of the 21st Century. As with all large projects developing and deploying new technologies, the NGNP has numerous risks that need to be identified, tracked, mitigated, and reduced in order for successful project completion. A Risk Management Plan (RMP) was created to outline the process the INL is using to manage the risks and reduction strategies for the NGNP Project.more » Integral to the RMP is the development and use of a Risk Management System (RMS). The RMS is a tool that supports management and monitoring of the project risks. The RMS does not only contain a risk register, but other functionality that allows decision makers, engineering staff, and technology researchers to review and monitor the risks as the project matures.« less

  1. 77 FR 34179 - Freedom of Information Act and Privacy Act Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... disclosure in FOIA decision making. This Final Rule parallels the procedures currently used by other agencies... Freedom of Information Act and Privacy Act Procedures AGENCY: Special Inspector General for Afghanistan... information from the Special Inspector General for Afghanistan Reconstruction under the Freedom of Information...

  2. Nuclear translocation of the cytoskeleton-associated protein, smALP, upon induction of skeletal muscle differentiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cambier, Linda; Pomies, Pascal, E-mail: pascal.pomies@crbm.cnrs.fr

    2011-06-17

    Highlights: {yields} The cytoskeleton-associated protein, smALP, is expressed in differentiated skeletal muscle. {yields} smALP is translocated from the cytoplasm to the nucleus of C2C12 myoblasts upon induction of myogenesis. {yields} The differentiation-dependent nuclear translocation of smALP occurs in parallel with the nuclear accumulation of myogenin. {yields} The LIM domain of smALP is essential for the nuclear accumulation of the protein. {yields} smALP might act in the nucleus to control some critical aspect of the muscle differentiation process. -- Abstract: The skALP isoform has been shown to play a critical role in actin organization and anchorage within the Z-discs of skeletalmore » muscles, but no data is available on the function of the smALP isoform in skeletal muscle cells. Here, we show that upon induction of differentiation a nuclear translocation of smALP from the cytoplasm to the nucleus of C2C12 myoblasts, concomitant to an up-regulation of the protein expression, occurs in parallel with the nuclear accumulation of myogenin. Moreover, we demonstrate that the LIM domain of smALP is essential for the nuclear translocation of the protein.« less

  3. Transportin mediates nuclear entry of DNA in vertebrate systems.

    PubMed

    Lachish-Zalait, Aurelie; Lau, Corine K; Fichtman, Boris; Zimmerman, Ella; Harel, Amnon; Gaylord, Michelle R; Forbes, Douglass J; Elbaum, Michael

    2009-10-01

    Delivery of DNA to the cell nucleus is an essential step in many types of viral infection, transfection, gene transfer by the plant pathogen Agrobacterium tumefaciens and in strategies for gene therapy. Thus, the mechanism by which DNA crosses the nuclear pore complex (NPC) is of great interest. Using nuclei reconstituted in vitro in Xenopus egg extracts, we previously studied DNA passage through the nuclear pores using a single-molecule approach based on optical tweezers. Fluorescently labeled DNA molecules were also seen to accumulate within nuclei. Here we find that this import of DNA relies on a soluble protein receptor of the importin family. To identify this receptor, we used different pathway-specific cargoes in competition studies as well as pathway-specific dominant negative inhibitors derived from the nucleoporin Nup153. We found that inhibition of the receptor transportin suppresses DNA import. In contrast, inhibition of importin beta has little effect on the nuclear accumulation of DNA. The dependence on transportin was fully confirmed in assays using permeabilized HeLa cells and a mammalian cell extract. We conclude that the nuclear import of DNA observed in these different vertebrate systems is largely mediated by the receptor transportin. We further report that histones, a known cargo of transportin, can act as an adaptor for the binding of transportin to DNA.

  4. Protein quality control at the inner nuclear membrane

    PubMed Central

    Khmelinskii, Anton; Blaszczak, Ewa; Pantazopoulou, Marina; Fischer, Bernd; Omnus, Deike J.; Le Dez, Gaëlle; Brossard, Audrey; Gunnarsson, Alexander; Barry, Joseph D.; Meurer, Matthias; Kirrmaier, Daniel; Boone, Charles; Huber, Wolfgang; Rabut, Gwenaël; Ljungdahl, Per O.; Knop, Michael

    2015-01-01

    The nuclear envelope is a double membrane that separates the nucleus from the cytoplasm. The inner nuclear membrane (INM) functions in essential nuclear processes including chromatin organization and regulation of gene expression1. The outer nuclear membrane is continuous with the endoplasmic reticulum (ER) and is the site of membrane protein synthesis. Protein homeostasis in this compartment is ensured by ER-associated protein degradation (ERAD) pathways that in yeast involve the integral membrane E3 ubiquitin ligases Hrd1 and Doa10 operating with the E2 ubiquitin-conjugating enzymes Ubc6 and Ubc72,3. However, little is known regarding protein quality control at the INM. Here we describe a protein degradation pathway at the INM mediated by the Asi complex consisting of the RING domain proteins Asi1 and Asi34. We report that the As complex functions together with the ubiquitin conjugating enzymes Ubc6andUbc7to degrade soluble and integral membrane proteins. Genetic evidence suggest that the Asi ubiquitin ligase defines a pathway distinct from but complementary to ERAD. Using unbiased screening with a novel genome-wide yeast library based on a tandem fluorescent protein timer (tFT)5, we identify more than 50 substrates of the Asi, Hrd1 and Doa10 E3 ubiquity ligases. We show that the Asi ubiquitin ligase is involved in degradation of mislocalised integral membrane proteins, thus acting to maintain and safeguard the identity of the INM. PMID:25519137

  5. ACTS propagation terminal update

    NASA Technical Reports Server (NTRS)

    Stutzman, Warren L.; Pratt, Tim

    1992-01-01

    The activities at Virginia Polytechnic Institute and State University in preparation for the February 1993 launch of ACTS are summarized. ACTS propagation terminals (APT) are being constructed to receive the 20 and 27.5 GHz ACTS beacon signals. Total power radiometers operating at the same frequencies are integrated into the terminal for use in level setting. Recent progress and plans for APT's are reported.

  6. Nuclear Disaster Preparedness Act

    THOMAS, 112th Congress

    Rep. Engel, Eliot L. [D-NY-17

    2011-05-03

    House - 05/04/2011 Referred to the Subcommittee on Economic Development, Public Buildings and Emergency Management. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  7. Nuclear Disaster Preparedness Act

    THOMAS, 113th Congress

    Rep. Engel, Eliot L. [D-NY-16

    2013-04-24

    House - 04/25/2013 Referred to the Subcommittee on Economic Development, Public Buildings and Emergency Management. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  8. Nuclear Power 2021 Act

    THOMAS, 112th Congress

    Sen. Bingaman, Jeff [D-NM

    2011-03-08

    Senate - 08/30/2011 Placed on Senate Legislative Calendar under General Orders. Calendar No. 137. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. Nuclear Power 2021 Act

    THOMAS, 111th Congress

    Sen. Bingaman, Jeff [D-NM

    2009-11-20

    Senate - 09/27/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 600. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  10. Nuclear Family Priority Act

    THOMAS, 111th Congress

    Rep. Gingrey, Phil [R-GA-11

    2009-02-04

    House - 03/16/2009 Referred to the Subcommittee on Immigration, Citizenship, Refugees, Border Security, and International Law. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. 78 FR 40515 - Privacy Act of 1974; Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-071] Privacy Act of 1974; Privacy Act System of Records AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Privacy... training associated with [[Page 40516

  12. Nuclear inertia and the decay modes of superheavy nuclei

    NASA Astrophysics Data System (ADS)

    Poenaru, D. N.; Gherghescu, R. A.; Greiner, Walter

    2013-10-01

    Superheavy nuclei produced up to now decay mainly by α emission and spontaneous fission. For atomic numbers larger than 121 cluster decay has a good chance to compete. While calculated α decay half-lives are in agreement with experimental data within one order of magnitude and cluster decay experiments are also very well accounted for, the discrepancy between theory and experiment can be as high as ten orders of magnitude for spontaneous fission. We analyze some ways of improving the accuracy: using a semiempirical formula for α decay and changing the parameters of analytical superasymmetric fission and of the universal curve for cluster decay. For spontaneous fission we act on nuclear dynamics based on potential barriers computed by the macroscopic-microscopic method and employing various nuclear inertia variation laws. Applications are illustrated for 284Cn and Z = 118-124 even-even parent nuclei. Communicated by Steffen Bass

  13. VIS/ACT: The next episode

    NASA Technical Reports Server (NTRS)

    Maney, Tucker; Hamburger, Henry

    1993-01-01

    VIS/ACT is a multi-media educational system for aircrew coordination training (ACT). Students view video segments, answer questions that are adjusted to individual performance, and engage in related activities. Although the system puts the student in a reactive critiquing role, it has proved effective in improving performance on active targeted ACT skills, in group simulation tasks. VIS/ACT itself is the product of coordination among three Navy agencies.

  14. Savannah River Site nuclear materials management plan FY 2017-2031

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Magoulas, V.

    The purpose of the Nuclear Materials Management Plan (herein referred to as “this Plan”) is to integrate and document the activities required to disposition the legacy and/or surplus Enriched Uranium (EU) and Plutonium (Pu) and other nuclear materials already stored or anticipated to be received by facilities at the Department of Energy (DOE) Savannah River Site (SRS) as well as the activities to support the DOE Tritium mission. It establishes a planning basis for EU and Pu processing operations in Environmental Management Operations (EMO) facilities through the end of their program missions and for the tritium through the National Nuclearmore » Security Administration (NNSA) Defense Programs (DP) facilities. Its development is a joint effort among the Department of Energy - Savannah River (DOE-SR), DOE – Environmental Management (EM), NNSA Office of Material Management and Minimization (M3), NNSA Savannah River Field Office (SRFO), and the Management and Operations (M&O) contractor, Savannah River Nuclear Solutions, LLC (SRNS). Life-cycle program planning for Nuclear Materials Stabilization and Disposition and the Tritium Enterprise may use this Plan as a basis for the development of the nuclear materials disposition scope and schedule. This Plan assumes full funding to accomplish the required project and operations activities. It is recognized that some aspects of this Plan are pre decisional with regard to National Environmental Policy Act (NEPA); in such cases new NEPA actions will be required.« less

  15. 9 CFR 55.7 - Claims not allowed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.7 Claims not allowed. (a) The Department will not... owner in violation of a law or regulation administered by the Secretary regarding animal disease, or in...

  16. 9 CFR 55.7 - Claims not allowed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.7 Claims not allowed. (a) The Department will not... owner in violation of a law or regulation administered by the Secretary regarding animal disease, or in...

  17. 9 CFR 55.7 - Claims not allowed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.7 Claims not allowed. (a) The Department will not... owner in violation of a law or regulation administered by the Secretary regarding animal disease, or in...

  18. 9 CFR 55.7 - Claims not allowed.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.7 Claims not allowed. (a) The Department will not... owner in violation of a law or regulation administered by the Secretary regarding animal disease, or in...

  19. 9 CFR 55.7 - Claims not allowed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES CONTROL OF CHRONIC WASTING DISEASE Chronic Wasting Disease Indemnification Program § 55.7 Claims not allowed. (a) The Department will not... owner in violation of a law or regulation administered by the Secretary regarding animal disease, or in...

  20. 24 CFR 18.1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... has been filed against the employee in his or her individual capacity as a result of conduct taken... charged in their individual capacities). (e) The employee may, thereafter, request indemnification to... personal damage claim, is contingent upon the availability of appropriated funds of the Department that are...

  1. [Judicial or administrative settlement of medical malpractice claims. Update on medical liability].

    PubMed

    Crégut, P

    2012-03-01

    Settlement of medical malpractice claims was radically changed by the Kouchner Law that set up a rapid, effective system of indemnification. Victims can choose between conventional court proceedings and a non-judicial conciliation procedure. Choice between the two processes depends on the circumstances of the case.

  2. 10 CFR 140.7 - Fees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... thousand kilowatts of thermal capacity authorized in the license; (ii) For indemnification from $399 million to $300 million inclusive, a fee of $24 per year per thousand kilowatts of thermal capacity... $18 per year per thousand kilowatts of thermal capacity authorized in the license; (iv) For...

  3. 10 CFR 140.7 - Fees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... thousand kilowatts of thermal capacity authorized in the license; (ii) For indemnification from $399 million to $300 million inclusive, a fee of $24 per year per thousand kilowatts of thermal capacity... $18 per year per thousand kilowatts of thermal capacity authorized in the license; (iv) For...

  4. 10 CFR 140.7 - Fees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... thousand kilowatts of thermal capacity authorized in the license; (ii) For indemnification from $399 million to $300 million inclusive, a fee of $24 per year per thousand kilowatts of thermal capacity... $18 per year per thousand kilowatts of thermal capacity authorized in the license; (iv) For...

  5. 10 CFR 140.7 - Fees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... thousand kilowatts of thermal capacity authorized in the license; (ii) For indemnification from $399 million to $300 million inclusive, a fee of $24 per year per thousand kilowatts of thermal capacity... $18 per year per thousand kilowatts of thermal capacity authorized in the license; (iv) For...

  6. 10 CFR 140.7 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... thousand kilowatts of thermal capacity authorized in the license; (ii) For indemnification from $399 million to $300 million inclusive, a fee of $24 per year per thousand kilowatts of thermal capacity... $18 per year per thousand kilowatts of thermal capacity authorized in the license; (iv) For...

  7. 14 CFR 1274.916 - Liability and risk of loss.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Liability and risk of loss. 1274.916 Section 1274.916 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS..., or indemnification of, developers of experimental aerospace vehicles. Liability and Risk of Loss July...

  8. 12 CFR 239.41 - Employment contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Employment contracts. 239.41 Section 239.41 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification; Employment Contracts § 239.41...

  9. 12 CFR 239.41 - Employment contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Employment contracts. 239.41 Section 239.41 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification; Employment Contracts § 239.41...

  10. 12 CFR 239.41 - Employment contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Employment contracts. 239.41 Section 239.41 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Indemnification; Employment Contracts § 239.41...

  11. Defense Nuclear Facilities Safety Board: Improvements Needed to Strengthen Internal Control and Promote Transparency

    DTIC Science & Technology

    2015-01-01

    results of those steps. GAO reviewed relevant federal laws, regulations , and guidance; analyzed DNFSB documents, including records of internal...agencies’ regulations on Sunshine Act meetings.11 We also interviewed a representative of the Sunlight Foundation, an organization focused on...Secretary’s role as operator and regulator of DOE’s defense nuclear facilities—to ensure adequate protection of public health and safety at these

  12. 10 CFR 2.103 - Action on applications for byproduct, source, special nuclear material, facility and operator...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... State Materials and Environmental Management Programs, or Director, Office of Nuclear Material Safety... Reorganization Act, and this chapter, he will issue a license. If the license is for a facility, or for receipt... operations area under parts 60 or 63 of this chapter, or if it is to receive and possess high-level...

  13. Progress on Cleaning Up the Only Commercial Nuclear Fuel Reprocessing Facility to Operate in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jackson, T. J.; MacVean, S. A.; Szlis, K. A.

    2002-02-26

    This paper describes the progress on cleanup of the West Valley Demonstration Project (WVDP), an environmental management project located south of Buffalo, NY. The WVDP was the site of the only commercial nuclear fuel reprocessing facility to have operated in the United States (1966 to 1972). Former fuel reprocessing operations generated approximately 600,000 gallons of liquid high-level radioactive waste stored in underground tanks. The U.S. Congress passed the WVDP Act in 1980 (WVDP Act) to authorize cleanup of the 220-acre facility. The facility is unique in that it sits on the 3,345-acre Western New York Nuclear Service Center (WNYNSC), whichmore » is owned by New York State through the New York State Energy Research and Development Authority (NYSERDA). The U.S. Department of Energy (DOE) has overall responsibility for the cleanup that is authorized by the WVDP Act, paying 90 percent of the WVDP costs; NYSERDA pays 10 percent. West Valley Nuclear Services Company (WVNSCO) is the management contractor at the WVDP. This paper will provide a description of the many accomplishments at the WVDP, including the pretreatment and near completion of vitrification of all the site's liquid high-level radioactive waste, a demonstration of technologies to characterize the remaining material in the high-level waste tanks, the commencement of decontamination and decommissioning (D&D) activities to place the site in a safe configuration for long-term site management options, and achievement of several technological firsts. It will also include a discussion of the complexities involved in completing the WVDP due to the various agency interests that require integration for future cleanup decisions.« less

  14. 75 FR 42130 - Notice of Lodging of Consent Decree Under the Clean Air Act; Clean Water Act; Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... DEPARTMENT OF JUSTICE Notice of Lodging of Consent Decree Under the Clean Air Act; Clean Water Act; Resource Conservation and Recovery Act; Safe Drinking Water Act; Toxic Substances Control Act; and the Reporting Requirements of the Emergency Planning and Community Right-To-Know Act and the Comprehensive Environmental Response, Compensation, and...

  15. The Nuclear Power/Nuclear Weapons Connection.

    ERIC Educational Resources Information Center

    Totten, Sam; Totten, Martha Wescoat

    1985-01-01

    Once they have nuclear power, most countries will divert nuclear materials from commercial to military programs. In excerpts from the book "Facing the Danger" (by Totten, S. and M. W., Crossing Press, 1984), five anti-nuclear activists explain how and why they have been addressing the nuclear connection. (RM)

  16. Development and characterization of a long-acting nanoformulated abacavir prodrug

    PubMed Central

    Singh, Dhirender; McMillan, JoEllyn; Hilaire, James; Gautam, Nagsen; Palandri, Diana; Alnouti, Yazen; Gendelman, Howard E; Edagwa, Benson

    2016-01-01

    Aim: A myristoylated abacavir (ABC) prodrug was synthesized to extend drug half-life and bioavailability. Methods: Myristoylated ABC (MABC) was made by esterifying myristic acid to the drug's 5-hydroxy-cyclopentene group. Chemical composition, antiretroviral activity, cell uptake and retention and cellular trafficking of free MABC and poloxamer nanoformulations of MABC were assessed by proton nuclear magnetic resonance and tested in human monocyte-derived macrophages. Pharmacokinetics of ABC and nanoformulated MABC were evaluated after intramuscular injection into mice. Results: MABC antiretroviral activity in monocyte-derived macrophages was comparable to native drug. Encasement of MABC into poloxamer nanoparticles extended drug bioavailability for 2 weeks. Conclusion: MABC synthesis and encasement in polymeric nanoformulations improved intracellular drug accumulation and demonstrate translational potential as part of a long-acting antiretroviral regimen. PMID:27456759

  17. 7 CFR 1215.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means the Popcorn Promotion, Research, and Consumer Information Act of 1995, Subtitle E of Title V of the...

  18. 7 CFR 1215.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means the Popcorn Promotion, Research, and Consumer Information Act of 1995, Subtitle E of Title V of the...

  19. 7 CFR 1215.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means the Popcorn Promotion, Research, and Consumer Information Act of 1995, Subtitle E of Title V of the...

  20. 7 CFR 1215.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means the Popcorn Promotion, Research, and Consumer Information Act of 1995, Subtitle E of Title V of the...

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