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Sample records for act program regulation

  1. 76 FR 10527 - Regulatory Flexibility Act: Section 610 Review of National Organic Program Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... Organic Program Regulations AGENCY: Agricultural Marketing Service, USDA. ACTION: Review and request for... National Organic Program (NOP) regulations (7 CFR part 205). This review will be conducted under criteria... Specialist, National Organic Program, USDA-AMS-NOP, 1400 Independence Ave., SW., Room 2646-So., Ag Stop...

  2. Guidance for applicants for state wellhead protection program assistance funds under the Safe Drinking Water Act. Appendix C. Wellhead Protection Program-applicable regulations

    SciTech Connect

    Not Available

    1987-06-01

    Appendix C is a companion document to the Guidance for Applicants for State Wellhead Protection Assistance Funds Under the Safe Drinking Water Act to explain EPA regulations applicable to the Wellhead Protection Program (WHP) and the assistance application form needed to request a program grant. These two documents are used to develop approvable assistance applications and to administer properly the funds awarded under the WHP program.

  3. Missouri State Plan for Special Education: Regulations Implementing Part C of the Individuals with Disabilities Education Act First Steps Program

    ERIC Educational Resources Information Center

    Nicastro, Chris L.

    2010-01-01

    The State of Missouri has adopted the definitions in 34 Code of Federal Regulations (CFR) 303.5-303.24 of the Part C regulations and selected terms as defined in 34 CFR 77.1 and 74.3 for use in implementing the State's early intervention program. The Department of Elementary and Secondary Education (DESE) is the lead agency responsible for…

  4. Biomass Program Recovery Act Factsheet

    SciTech Connect

    2010-03-01

    The Biomass Program has awarded about $718 million in American Recovery and Reinvestment Act (Recovery Act) funds. The projects the Program is supporting are intended to: Accelerate advanced biofuels research, development, and demonstration; Speed the deployment and commercialization of advanced biofuels and bioproducts; Further the U.S. bioindustry through market transformation and creating or saving a range of jobs.

  5. Overview of the ACT program

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr.

    1992-01-01

    NASA's Advanced Composites Program (ACT) was initiated in 1988. A National Research Announcement was issued to solicit innovative ideas that could significantly contribute to development and demonstration of an integrated technology data base and confidence level that permits cost-effective use of composite primary structures in transport aircraft. Fifteen contracts were awarded by the Spring of 1989 and the participants include commercial and military airframe manufacturers, materials developers and suppliers, universities, and government laboratories. The program approach is to develop materials, structural mechanics methodology, design concepts, and fabrication procedures that offer the potential to make composite structures cost-effective compared to aluminum structure. Goals for the ACT program included 30-50 percent weight reduction, 20-25 percent acquisition cost reduction, and provided the scientific basis for predicting materials and structures performance. This paper provides an overview of the ACT program status, plans, and selected technical accomplishments. Sixteen additional papers, which provide more detailed information on the research and development accomplishments, are contained in this publication.

  6. 75 FR 61035 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... Education loan program; or (2) any private education loan as defined in the Truth in Lending Act, including... expenses,'' each of which is defined in the HEOA in the context of the Truth in Lending Act (TILA). Section... the Truth in Lending Act, as added by section 1011 of the HEOA. In turn, the HEOA defines a...

  7. 75 FR 37287 - Privacy Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... / Tuesday, June 29, 2010 / Rules and Regulations#0;#0; ] RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD 4 CFR Part 200 RIN 0430-AA03 Privacy Act Regulations AGENCY: Recovery Accountability and Transparency Board ACTION: Final rule. SUMMARY: The Recovery Accountability and Transparency Board (Board) amends...

  8. Missouri State Plan for Special Education: Regulations Implementing Part C of the Individuals with Disabilities Education Act First Steps Program. Revised

    ERIC Educational Resources Information Center

    Nicastro, Chris L.

    2012-01-01

    The State of Missouri has adopted the definitions in 34 Code of Federal Regulations (CFR) 303.5-303.24 of the Part C regulations and selected terms as defined in 34 CFR 77.1 and 74.3 for use in implementing the State's early intervention program. The Department of Elementary and Secondary Education (DESE) is the lead agency responsible for…

  9. Title I, Higher Education Act Program Abstracts.

    ERIC Educational Resources Information Center

    Miller, Lorna M., Ed.

    The 1979 edition of the Title I, Higher Education Act Program Abstracts is presented. Directed toward state Title I, HEA administrators, the program abstracts are made available in order to encourage nationwide program replication of those tested and evaluated programs that have been conducted with Title I support by institutions of higher…

  10. 75 FR 82217 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... Joint Final Rule The agencies' CRA regulations establish CRA performance standards for small and... between the standards used to evaluate savings associations and the standards used to evaluate banks. 72... Procedure Act (APA), an agency may, for good cause, find (and incorporate the finding and a brief...

  11. 76 FR 79529 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... of the Joint Final Rule The agencies' CRA regulations establish CRA performance standards for small... the Administrative Procedure Act (APA), an agency may, for good cause, find (and incorporate the.... Under 5 U.S.C. 553(d)(3) of the APA, the required publication or service of a substantive rule shall...

  12. 77 FR 75521 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ... CFR Part 228 FEDERAL DEPOSIT INSURANCE CORPORATION 12 CFR Part 345 RIN 3064-AD90 Community... agencies) are amending their Community Reinvestment Act (CRA) regulations to adjust the asset-size..., 2013. FOR FURTHER INFORMATION CONTACT: OCC: Margaret Hesse, Special Counsel, Community and Consumer...

  13. 78 FR 18473 - Army Privacy Act Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... Department of the Army 32 CFR Part 505 Army Privacy Act Program AGENCY: Department of the Army, DoD. ACTION... Litigation Division when complaints citing the Privacy Act are filed in order to correct the mailing address in Sec. 505.12. The address for notifying the Army Litigation Division of cases citing the...

  14. NASA's Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia

    2003-01-01

    Marshall Space Flight Center (MSFC) was selected as the Principal Center for review of Clean Air Act (CAA) regulations. The CAA Principal Center is tasked to: 1) Provide centralized support to NASA/HDQ Code JE for the management and leadership of NASA's CAA regulation review process; 2) Identify potential impact from proposed CAA regulations to NASA program hardware and supporting facilities. The Shuttle Environmental Assurance Initiative, one of the responsibilities of the NASA CAA Working Group (WG), is described in part of this viewgraph presentation.

  15. 75 FR 63425 - Regulations Implementing the Longshore and Harbor Workers' Compensation Act: Recreational Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... of Workers' Compensation Programs 20 CFR Part 701 RIN 1240-AA02 Regulations Implementing the Longshore and Harbor Workers' Compensation Act: Recreational Vessels AGENCY: Office of Workers' Compensation... Workers' Compensation Programs (OWCP) is republishing the Notice of Proposed Rulemaking entitled...

  16. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  17. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  18. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  19. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  20. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  1. 78 FR 17176 - Federal Acquisition Regulation; Defense Base Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... Federal Acquisition Regulation; Defense Base Act AGENCIES: Department of Defense (DoD), General Services... Act as extended by the Defense Base Act. DATES: Interested parties should submit written comments to... Act as extended by the Defense Base Act. II. Discussion and Analysis The Defense Base Act of...

  2. The Kentucky Civil Rights Act: Explanation, the Act, Regulations.

    ERIC Educational Resources Information Center

    Kentucky State Commission on Human Rights, Frankfort.

    The Kentucky Civil Rights Act, introduced on January 4, 1966, enacted January 27, 1966 and effective July 1, 1966 is said to meet the requirements of the Federal Civil Rights Act of 1964. In 1968, the Act was amended to prohibit housing discrimination. In 1972, the coverage of the Act was extended to prohibit employment discrimination because of…

  3. The French Space Operations Act: Technical Regulations

    NASA Astrophysics Data System (ADS)

    Lazare, B.

    2013-12-01

    The French Space Operations Act (FSOA) [1] stipulates that one of the National Technical Regulations' prime objectives is to protect people, property, public health and the environment. Compliance with these Technical Regulations has been mandatory since 10 December, 2010 for space operations by French space operators and for space operations conducted on French territory. The space safety requirements and regulations governing procedures are based on national and international best practices and experience. A critical design review of the space system and procedures shall be carried out by applicant space operators, in order to verify compliance with the Technical Regulations. An independent technical assessment of the operation is delegated to CNES. The principles applied when drafting the Technical Regulations are as follows: requirements must, as far as possible, establish the rules according to the objective to be obtained, rather than how it is to be achieved; requirements must give preference to international standards recognised as being state of the art; requirements must take previous experience into account. The Technical Regulations are divided into three sections covering requirements common to the launch, control and return of a space object. A special section will cover specific rules to be applied at the Guiana Space Centre. The main topics addressed by the Technical Regulations are: operator safety management system; study of risks to people, property, public health and the Earth's environment; impact study on the outer space environment: space debris generated by the operation; planetary protection. The first version of the Technical Regulations [2], issued in March 2011, is dedicated to unmanned space systems.

  4. Environmental Guidance Program Reference Book: Marine Protection, Research, and Sanctuaries Act and Marine Mammal Protection Act. Revision 3

    SciTech Connect

    Not Available

    1988-01-31

    Two laws governing activities in the marine environment are considered in this Reference Book. The Marine Protection, Research, and Sanctuaries Act (MPRSA, P.L. 92-532) regulates ocean dumping of waste, provides for a research program on ocean dumping, and provides for the designation and regulation of marine sanctuaries. The Marine Mammal Protection Act (MMPA, P.L. 92-522) establishes a federal program to protect and manage marine mammals. The Fishery Conservation and Management Act (FCMA, P.L. 94-265) establishes a program to regulate marine fisheries resources and commercial marine fishermen. Because the Department of Energy (DOE) is not engaged in any activities that could be classified as fishing under FCMA, this Act and its regulations have no implications for the DOE; therefore, no further consideration of this Act is given within this Reference Book. The requirements of the MPRSA and the MMPA are discussed in terms of their implications for the DOE.

  5. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  6. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  7. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  8. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  9. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  10. 76 FR 43585 - Bank Secrecy Act Regulations; Definitions and Other Regulations Relating to Money Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... Regulations; Definitions and Other Regulations Relating to Money Services Businesses AGENCY: Treasury... Proposed Rulemaking, Definitions and Other Regulations Relating to Money Services Businesses, 74 FR 22129... to the Bank Secrecy Act Regulations-- Definitions and Other Regulations Relating to Money...

  11. Regulations Under the Americans With Disabilities Act; Genetic Information Nondiscrimination Act. Final rule.

    PubMed

    2016-05-17

    The Equal Employment Opportunity Commission (EEOC or Commission) is issuing its final rule to amend the regulations and interpretive guidance implementing Title I of the Americans with Disabilities Act (ADA) to provide guidance on the extent to which employers may use incentives to encourage employees to participate in wellness programs that ask them to respond to disability-related inquiries and/or undergo medical examinations. This rule applies to all wellness programs that include disability-related inquiries and/or medical examinations whether they are offered only to employees enrolled in an employer-sponsored group health plan, offered to all employees regardless of whether they are enrolled in such a plan, or offered as a benefit of employment by employers that do not sponsor a group health plan or group health insurance. Published elsewhere in this issue of the Federal Register, the EEOC also issued a final rule to amend the regulations implementing Title II of the Genetic Information Nondiscrimination Act (GINA) that addresses the extent to which employers may offer incentives for an employee's spouse to participate in a wellness program.

  12. 75 FR 5166 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration... regarding protections for such persons. The Privacy Act, as amended, regulates the use of computer matching... denying a person's benefits or payments. B. SSA Computer Matches Subject to the Privacy Act We have...

  13. Safe drinking water act: Amendments, regulations and standards

    SciTech Connect

    Calabrese, E.J.; Gilbert, C.E.; Pastides, H.

    1989-01-01

    This book approaches the topic of safe drinking water by communicating how the EPA has responded to the mandates of Congress. Chapter 1 summarizes what is and will be involved in achieving safe drinking water. Chapter 2 describes the historical development of drinking water regulations. Chapter 3 summarizes the directives of the Safe Drinking Water Act Amendments of 1986. Chapters 4 through 9 discuss each phase of the regulatory program in turn. Specific problems associated with volatile organic chemicals, synthetic organics, inorganic chemicals, and microbiological contaminants are assessed in Chapter 4 and 5. The unique characteristics of radionuclides and their regulation are treated in Chapter 6. The disinfection process and its resultant disinfection by-products are presented in Chapter 7. The contaminant selection process and the additional contaminants to be regulated by 1989 and 1991 and in future years are discussed in Chapters 8 and 9. EPA's Office of Drinking Water's Health Advisory Program is explained in Chapter 10. The record of public water system compliance with the primary drinking water regulations is detailed in Chapter 11. Chapter 12 offers a nongovernmental perspective on the general quality of drinking water and how this is affected by a wide range of drinking water treatment technologies. Separate abstracts are processed for 5 chapters in this book for inclusion in the appropriate data bases.

  14. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2), use the following clause: Buy American Act and Balance...

  15. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American Act and...

  16. 32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false DoD Freedom of Information Act Program Components F Appendix F to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE... REGULATION Pt. 286, App. F Appendix F to Part 286—DoD Freedom of Information Act Program Components Office...

  17. 32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false DoD Freedom of Information Act Program Components F Appendix F to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE... REGULATION Pt. 286, App. F Appendix F to Part 286—DoD Freedom of Information Act Program Components Office...

  18. NASA Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia; Munafo, Paul M. (Technical Monitor)

    2002-01-01

    The Clean Air Act (CAA) regulations have greatly impacted materials and processes utilized in the manufacture of aerospace hardware. Code JE/ NASA's Environmental Management Division at NASA Headquarters recognized the need for a formal, Agency-wide review process of CAA regulations. Marshall Space Flight Center (MSFC) was selected as the 'Principal Center for Review of Clean Air Act Regulations'. This presentation describes the centralized support provided by MSFC for the management and leadership of NASA's CAA regulation review process.

  19. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM 12... Reserve System. ACTION: Final rule. SUMMARY: The Board of Governors of the Federal Reserve System (Board... to consult with the Board's Employee Assistance Program counselor to determine whether the...

  20. The McKinney Act: A Program Guide.

    ERIC Educational Resources Information Center

    Interagency Council on the Homeless.

    This publication is a guide to programs created by the Stewart B. McKinney Homeless Assistance Act of 1987. An opening section describes the McKinney Act itself and the agency that developed the guide. The bulk of the publication lists and describes 24 McKinney Act programs grouped under the following headings: (1) education and training programs;…

  1. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the Program Fraud Civil Remedies Act of 1986 (31 U.S.C. 3801-U.S.C. 3831) which provides for civil penalties...

  2. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the Program Fraud Civil Remedies Act of 1986 (31 U.S.C. 3801-U.S.C. 3831) which provides for civil penalties...

  3. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the Program Fraud Civil Remedies Act of 1986 (31 U.S.C. 3801-U.S.C. 3831) which provides for civil penalties...

  4. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the Program Fraud Civil Remedies Act of 1986 (31 U.S.C. 3801-U.S.C. 3831) which provides for civil penalties...

  5. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the Program Fraud Civil Remedies Act of 1986 (31 U.S.C. 3801-U.S.C. 3831) which provides for civil penalties...

  6. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  7. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  8. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  9. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  10. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  11. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  12. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  13. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  14. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  15. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  16. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  17. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  18. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  19. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  20. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  1. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  2. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  3. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  4. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  5. 75 FR 20298 - Privacy Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... effectively compile investigatory material to prevent and detect fraud, waste, and abuse and perform its other... records, ``RATB--11--RATB Investigative Files'' and ``RATB--12--RATB Fraud Hotline Program Files... the RATB Fraud Hotline Program Files (RATB--12) system of records from the following provisions of 5...

  6. 78 FR 79283 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... CRA purposes by the OCC, Board, and FDIC on August 2, 2005, effective September 1, 2005. 70 FR 44256... Act (HMDA). 70 FR 12148 (Mar. 11, 2005). See 12 U.S.C. 2808; 12 CFR 203.2(e)(1). On March 22, 2007... other federal banking agencies in its CRA rule previously set forth at 12 CFR 563e. 72 FR 13429 (Mar....

  7. 78 FR 15733 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department of... Act of 1974; Computer Matching Program between the Department of Homeland Security/U.S. Citizenship...: This document provides notice of the existence of a computer matching program between the Department...

  8. 78 FR 15734 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department of... Act of 1974; Computer Matching Program between the Department of Homeland Security/U.S. Citizenship... document provides notice of the existence of a computer matching program between the Department of...

  9. 78 FR 15732 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department of... Act of 1974; Computer Matching Program between the Department of Homeland Security/U.S. Citizenship... provides notice of the existence of a computer matching program between the Department of Homeland...

  10. 78 FR 15731 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department of... Act of 1974; Computer Matching Program between the Department of Homeland Security/U.S. Citizenship... the existence of a computer matching program between the Department of Homeland...

  11. 78 FR 15730 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: U.S. Citizenship...: Privacy Act of 1974; Computer Matching Program between the Department of Homeland Security, U.S... notice of the existence of a computer matching program between the Department of Homeland Security,...

  12. 78 FR 16564 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Office of Personnel Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Office of Personnel Management... Privacy Act We have taken action to ensure that all of our computer matching programs comply with the... the Computer Matching and Privacy Protection Act of 1998, and the regulations and guidance...

  13. 75 FR 36270 - Appraisal Subcommittee; Appraiser Regulation; Privacy Act Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... INSTITUTIONS EXAMINATION COUNCIL 12 CFR Part 1102 Appraisal Subcommittee; Appraiser Regulation; Privacy Act Implementation AGENCY: Appraisal Subcommittee of the Federal Financial Institutions Examination Council...-7577 or alice@asc.gov ; Appraisal Subcommittee; 1401 H Street, NW., Suite 760, Washington, DC...

  14. 77 FR 57043 - Regulations Under the Fur Products Labeling Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ...The Federal Trade Commission proposes to amend its Regulations under the Fur Products Labeling Act to update its Fur Products Name Guide, provide more labeling flexibility, incorporate recently enacted Truth in Fur Labeling Act provisions, and eliminate unnecessary requirements. The Commission does not propose changing or providing alternatives to the required name on labels for nyctereutes......

  15. 77 FR 74347 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... GENERAL ON INTEGRITY AND EFFICIENCY 5 CFR Chapter XCVIII Freedom of Information Act Regulations AGENCY... implement the Freedom of Information Act (FOIA). The final rule describes the policies and procedures for... provide the procedures and guidelines under which CIGIE will implement the Freedom of Information...

  16. 77 FR 66539 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... CONCILIATION SERVICE 29 CFR Part 1401 RIN 3076-AA06 Freedom of Information Act Regulations AGENCY: Federal... Mediation and Conciliation Service (FMCS) rules relating to the Freedom of Information Act (FOIA). The final... Administrative practice and procedure, Freedom of information. For the reasons stated in the preamble,...

  17. 75 FR 79278 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... services by financial institutions that support, enable, or facilitate projects or activities that meet the... Program (NSP). The final rule provides favorable CRA consideration of such activities that, pursuant to... geographies in NSP target areas designated as ``areas of greatest need.'' Covered activities are...

  18. 77 FR 43639 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA..., SSA, as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy... persons. The Privacy Act, as amended, regulates the use of computer matching by Federal agencies...

  19. 77 FR 54943 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA..., SSA, as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy... persons. The Privacy Act, as amended, regulates the use of computer matching by Federal agencies...

  20. 77 FR 75362 - Government in the Sunshine Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... From the Federal Register Online via the Government Publishing Office EQUAL EMPLOYMENT OPPORTUNITY COMMISSION 29 CFR Part 1612 Government in the Sunshine Act Regulations CFR Correction 0 In Title 29 of the Code of Federal Regulations, Parts 900 to 1899, revised as of July 1, 2012, on page 266, in Sec....

  1. National Weatherization Assistance Program Characterization Describing the Recovery Act Period

    SciTech Connect

    Tonn, Bruce Edward; Rose, Erin M.; Hawkins, Beth A.

    2015-10-01

    This report characterizes the U.S. Department of Energy s Weatherization Assistance Program (WAP) during the American Recovery and Reinvestment Act of 2009 (Recovery Act) period. This research was one component of the Recovery Act evaluation of WAP. The report presents the results of surveys administered to Grantees (i.e., state weatherization offices) and Subgrantees (i.e., local weatherization agencies). The report also documents the ramp up and ramp down of weatherization production and direct employment during the Recovery Act period and other challenges faced by the Grantees and Subgrantees during this period. Program operations during the Recovery Act (Program Year 2010) are compared to operations during the year previous to the Recovery Act (Program Year 2008).

  2. 76 FR 11435 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ACTION: Notice--Computer... to the Computer Matching and Privacy Protection Act of 1988, Public Law 100-503, the Computer... (OMB) guidance on the conduct of computer matching programs, notice is hereby given of the renewal...

  3. 78 FR 21713 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  4. 78 FR 38724 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department of... Act of 1974; Computer Matching Program between the Department of Homeland Security/U.S. Citizenship... provides notice of the existence of a Computer Matching Agreement that establishes a computer...

  5. 78 FR 50146 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  6. 76 FR 47299 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  7. 75 FR 54966 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  8. 77 FR 56824 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ACTION: Notice. Overview Information: Privacy Act of 1974; Computer Matching Program between the U.S. Department of Education and the... Naturalization Service SUMMARY: This document provides notice of the continuation of a computer matching...

  9. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of Payments Program Certificate. Buy American Act—Balance of Payments Program Certificate (DEC 2009)...

  10. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American and Balance...

  11. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American and Balance...

  12. Report: EPA Relying on Existing Clean Air Act Regulations to Reduce Atmospheric Deposition to the Chesapeake Bay and its Watershed

    EPA Pesticide Factsheets

    Report #2007-P-00009, February 28, 2007. EPA’s Chesapeake Bay Program Office is relying on anticipated nitrogen deposition reductions from Clean Air Act (CAA) regulations already issued by EPA, combined with other non-air sources' anticipated reductions.

  13. 20 CFR 626.4 - Table of contents for the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....601Applied VST budgeting. Subpart G—Experimental, Research, and Demonstration Projects 638.710Experimental, research, and demonstration projects. Subpart H—Administrative Provisions 638.800Program management. 638..., DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.4 Table...

  14. Evaluating Federal Social Programs: An Uncertain Act.

    ERIC Educational Resources Information Center

    Levitan, Sar A.; Wurzburg, Gregory K.

    This study of the federal government's evaluation of social programs indicates that it is virtually impossible to establish a bias-free, valid, and reliable system of inquiry to determine the effects of social programs. Divided into five chapters, the document examines the aspirations and limitations of evaluations, methodology, evaluation in the…

  15. 77 FR 38610 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ACTION: Notice--Computer... document provides notice of the continuation of the computer matching program between the Departments of... of Defense and the Department of Education created a computer matching program. The purpose of...

  16. 75 FR 69988 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ] ACTION: Notice--Computer... Department of Education implemented a computer matching program. The 18-month computer matching agreement... announce the continued operation of the computer matching program and to provide certain...

  17. 77 FR 75499 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Matching Program. SUMMARY: Notice is hereby given that the Department of Veterans Affairs (VA) intends to conduct a recurring computer matching program. This will match personnel...

  18. 76 FR 1410 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Defense Manpower Data Center (DMDC), DoD. ACTION: Notice of a Computer Matching Program. SUMMARY: Subsection (e)(12) of the Privacy... or revised computer matching program by the matching agency for public comment. The Department...

  19. 20 CFR 668.870 - What is “program income” and how is it regulated in the INA program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What is âprogram incomeâ and how is it regulated in the INA program? 668.870 Section 668.870 Employees' Benefits EMPLOYMENT AND TRAINING... ACT Administrative Requirements § 668.870 What is “program income” and how is it regulated in the...

  20. 77 FR 49849 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Office of Child Support...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Office of Child Support... above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988... persons. The Privacy Act, as amended, regulates the use of computer matching by Federal agencies...

  1. 75 FR 32833 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Office of Personnel Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Office of Personnel Management... the provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer... regarding protections for such persons. The Privacy Act, as amended, regulates the use of computer...

  2. 75 FR 43579 - Privacy Act of 1974; Computer Matching Program Between the Office of Personnel Management and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program Between the Office of Personnel Management and... accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer Matching and Privacy... individuals. The Privacy Act, as amended, regulates the use of computer matching by Federal agencies...

  3. 77 FR 24757 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match.... SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Public Law (Pub.... The Privacy Act, as amended, regulates the use of computer matching by Federal agencies when...

  4. 77 FR 38880 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Railroad Retirement Board (SSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Railroad Retirement Board (SSA... above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988.... The Privacy Act, as amended, regulates the use of computer matching by Federal agencies when...

  5. 78 FR 37875 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Bureau of the Fiscal Service...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Bureau of the Fiscal Service... regarding protections for such persons. The Privacy Act, as amended, regulates the use of computer matching..., or denying a person's benefits or payments. ] B. SSA Computer Matches Subject to the Privacy Act...

  6. 78 FR 6216 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Office of the Secretary 43 CFR Part 2 RIN 1093-AA15 Freedom of Information Act Regulations AGENCY: Office of the Secretary, Interior. ACTION: Final rule; correction. SUMMARY: This document...

  7. 76 FR 78977 - Real Estate Settlement Procedures Act (Regulation X)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... December 20, 2011 Part II Bureau of Consumer Financial Protection 12 CFR Part 1024 Real Estate Settlement... RIN 3170-AA06 Real Estate Settlement Procedures Act (Regulation X) AGENCY: Bureau of Consumer... Department of Housing and Urban Development's (HUD's) rulemaking authority for the Real Estate...

  8. 75 FR 53005 - Privacy Act of 1974, as amended; Notice of Computer Matching Program (Railroad Retirement Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Privacy Act of 1974, as amended; Notice of Computer Matching Program (Railroad Retirement Board and Social...-mail at tim.grant@rrb.gov . SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy... Register for all matching programs. The Privacy Act, as amended, regulates the use of computer matching...

  9. 75 FR 17788 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management. ACTION: Notice--computer matching between the Office of Personnel Management and the Social Security Administration. SUMMARY: In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the...

  10. 77 FR 74518 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management. ACTION: Notice--computer matching between the Office of Personnel Management and the Social Security Administration. SUMMARY: In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the...

  11. 78 FR 1275 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management. ACTION: Notice--computer matching between the Office of Personnel Management and the Social Security Administration (Computer Matching Agreement 1071). SUMMARY: In accordance with the Privacy Act of 1974 (5...

  12. 75 FR 31819 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management. AGENCY: Notice--computer matching between the Office of Personnel Management and the Social Security Administration. SUMMARY: In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the...

  13. 78 FR 35647 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management. ACTION: Notice of computer matching between the Office of Personnel Management and the Social Security... Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503), Office of Management and...

  14. 76 FR 24564 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Internal Revenue Service Privacy Act of 1974: Computer Matching Program AGENCY: Internal Revenue Service... Information to Federal, State and Local Agencies (DIFSLA) Computer Matching Program. DATES: Effective Date... copy of the applicable computer matching agreement at the address provided above. Purpose The...

  15. 78 FR 32711 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION... recurring computer-matching program matching Internal Revenue Service (IRS) Federal tax information with...

  16. 76 FR 50198 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... Privacy Act of 1974; Computer Matching Program AGENCY: Office of the Inspector General, U.S. Department of Education. ACTION: Notice of computer matching between the U.S. Department of Education and the U.S. Office... Management and Budget (OMB) ] guidelines on the conduct of computer matching programs, notice is hereby...

  17. 75 FR 33838 - National Environmental Policy Act; Scientific Balloon Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... Space Flight Center's Wallops Flight Facility, Wallops Island, VA 23337. Comments also may be submitted... Program Manager, NASA Goddard Space Flight Center's Wallops Flight Facility; telephone 757-824-2319; or... SPACE ADMINISTRATION National Environmental Policy Act; Scientific Balloon Program AGENCY:...

  18. 20 CFR 669.150 - How are regulations established for this program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false How are regulations established for this... LABOR NATIONAL FARMWORKER JOBS PROGRAM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Purpose and Definitions § 669.150 How are regulations established for this program? In developing regulations for...

  19. 44 CFR 7.912 - To what programs or activities does this regulation apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... activities does this regulation apply? 7.912 Section 7.912 Emergency Management and Assistance FEDERAL... Financial Assistance From FEMA General § 7.912 To what programs or activities does this regulation apply? (a) The Act and this regulation apply to each FEMA recipient and to each program or activity operated...

  20. Balancing act creating the right regulation for coal combustion waste

    SciTech Connect

    Manuel, J.

    2009-11-15

    The December 2008 collapse of a coal ash pond in Tennessee threw safe management of coal combustion waste (CCW) into the spotlight. Millions of tons of CCW are produced in the United States each year, and a large percentage of that is recycled. The US Environmental Protection Agency is pursuing a host of initiatives that could directly or indirectly affect the disposition of CCW. States, too, are taking a look at how they regulate CCW. Among the options is the possibility of regulating CCW under the Resource Conservation and Recovery Act, a move that could have far-reaching implications for both the recycling and the disposal of this waste.

  1. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of... Act—Balance of Payments Program Certificate (DEC 2009) (a) Definitions. “Commercially available...

  2. 78 FR 45513 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... of the computer matching program is to exchange personal data for purposes of identifying individuals... Internet at http://www.regulations.gov as they are received without change, including any personal.... The purpose of the computer matching program is to exchange personal data for purposes of...

  3. 20 CFR 668.870 - What is “program income” and how is it regulated in the INA program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false What is âprogram incomeâ and how is it regulated in the INA program? 668.870 Section 668.870 Employees' Benefits EMPLOYMENT AND TRAINING... WORKFORCE INVESTMENT ACT Administrative Requirements § 668.870 What is “program income” and how is...

  4. 75 FR 59780 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Railroad Retirement Board (RRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Railroad Retirement Board (RRB... as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection... persons. The Privacy Act, as amended, regulates the use of computer matching by Federal agencies...

  5. 76 FR 78483 - S.A.F.E. Mortgage Licensing Act (Regulations G & H)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... PROTECTION 12 CFR Part 1007 and 1008 RIN 3170-AA06 S.A.F.E. Mortgage Licensing Act (Regulations G & H) AGENCY... Enforcement for Mortgage Licensing Act (S.A.F.E. Act), the Bureau is publishing for public comment an interim final rule establishing a new Regulation G (S.A.F.E. Mortgage Licensing Act--Federal Registration...

  6. 48 CFR 52.222-13 - Compliance with Davis-Bacon and Related Act Regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-Bacon and Related Act Regulations. 52.222-13 Section 52.222-13 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.222-13 Compliance with Davis-Bacon and Related Act Regulations. As prescribed in 22.407(a), insert the following clause: Compliance With Davis-Bacon and Related Act...

  7. 48 CFR 52.222-13 - Compliance with Davis-Bacon and Related Act Regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-Bacon and Related Act Regulations. 52.222-13 Section 52.222-13 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.222-13 Compliance with Davis-Bacon and Related Act Regulations. As prescribed in 22.407(a), insert the following clause: Compliance With Davis-Bacon and Related Act...

  8. 48 CFR 52.222-13 - Compliance with Davis-Bacon and Related Act Regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-Bacon and Related Act Regulations. 52.222-13 Section 52.222-13 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.222-13 Compliance with Davis-Bacon and Related Act Regulations. As prescribed in 22.407(a), insert the following clause: Compliance With Davis-Bacon and Related Act...

  9. 48 CFR 52.222-13 - Compliance with Davis-Bacon and Related Act Regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-Bacon and Related Act Regulations. 52.222-13 Section 52.222-13 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.222-13 Compliance with Davis-Bacon and Related Act Regulations. As prescribed in 22.407(a), insert the following clause: Compliance With Davis-Bacon and Related Act...

  10. 75 FR 69009 - Acquisition Regulation: Socioeconomic Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Parts 919, 922, 923, 924, 925, 926, and 952 RIN 1991-AB87 Acquisition Regulation: Socioeconomic Programs... D--Socioeconomic Programs to conform it to the FAR. Changes are to DEAR parts 919, 922, 923, 925... in the introductory text to remove the ``.'' and adding in its place ``--''. 6. Subpart 922.6...

  11. 20 CFR 669.150 - How are regulations established for this program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false How are regulations established for this... LABOR (CONTINUED) NATIONAL FARMWORKER JOBS PROGRAM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Purpose and Definitions § 669.150 How are regulations established for this program? In developing...

  12. 20 CFR 669.150 - How are regulations established for this program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false How are regulations established for this... LABOR (CONTINUED) NATIONAL FARMWORKER JOBS PROGRAM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Purpose and Definitions § 669.150 How are regulations established for this program? In developing...

  13. Health Careers Opportunity Program (HCOP). Section 787 (Public Health Service Act). Program Guide.

    ERIC Educational Resources Information Center

    Department of Health and Human Services, Washington, DC.

    This document summarizes the requirements and guidelines for the Health Careers Opportunity Program (HCOP). This program is authorized by Section 787 of the Public Health Service Act to make grants to and contracts with postsecondary institutions to carry out programs which assist individuals from disadvantaged backgrounds to enter and graduate…

  14. Patient Protection and Affordable Care Act; establishment of exchanges and qualified health plans; Small Business Health Options Program. Final rule.

    PubMed

    2013-06-04

    This final rule implements provisions of the Patient Protection and Affordable Care Act and the Health Care and Education Reconciliation Act of 2010 (collectively referred to as the Affordable Care Act) related to the Small Business Health Options Program (SHOP). Specifically, this final rule amends existing regulations regarding triggering events and special enrollment periods for qualified employees and their dependents and implements a transitional policy regarding employees' choice of qualified health plans (QHPs) in the SHOP.

  15. 77 FR 43081 - Federal Acquisition Regulation; Information Collection; Buy American Act-Free Trade Agreements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... Regulation; Information Collection; Buy American Act--Free Trade Agreements--Israeli Trade Act Certificate... previously approved information collection requirement concerning the Buy American Act--Free Trade Agreements..., Buy American Act--Free Trade Agreements--Israeli Trade Act Certificate, by any of the...

  16. Adaptive Equilibrium Regulation: A Balancing Act in Two Timescales.

    PubMed

    Boker, Steven M

    2015-03-01

    An equilibrium involves a balancing of forces. Just as one maintains upright posture in standing or walking, many self-regulatory and interpersonal behaviors can be framed as a balancing act between an ever changing environment and within-person processes. The emerging balance between person and environment, the equilibria, are dynamic and adaptive in response to development and learning. A distinction is made between equilibrium achieved solely due to a short timescale balancing of forces and a longer timescale preferred equilibrium which we define as a state towards which the system slowly adapts. Together, these are developed into a framework that this article calls Adaptive Equilibrium Regulation (ÆR), which separates a regulatory process into two timescales: a faster regulation that automatically balances forces and a slower timescale adaptation process that reconfigures the fast regulation so as to move the system towards its preferred equilibrium when an environmental force persists over the longer timescale. This way of thinking leads to novel models for the interplay between multiple timescales of behavior, learning, and development.

  17. 75 FR 79964 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ...EPA is finalizing amendments to certain of the Renewable Fuel Standard program regulations that were published on March 26, 2010, and that took effect on July 1, 2010 (``the RFS2 regulations''). Following publication of the RFS2 regulations, promulgated in response to the requirements of the Energy Independence and Security Act of 2007, EPA discovered some technical errors and areas within the......

  18. 75 FR 26025 - Regulation of Fuels and Fuel Additives: Modifications to Renewable Fuel Standard Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ...EPA is taking direct final action to amend certain of the Renewable Fuel Standard program regulations published on March 26, 2010, that are scheduled to take effect on July 1, 2010 (the ``RFS2 regulations''). Following publication of the RFS2 regulations, promulgated in response to the requirements of the Energy Independence and Security Act of 2007, EPA discovered some technical errors and......

  19. Coastal Zone Management Act and related legislation: Revision 3. Environmental Guidance Program Reference Book

    SciTech Connect

    Not Available

    1993-10-15

    In recognition of the increasing pressures upon the nation`s coastal resources, Congress enacted the Coastal Zone Management Act in 1972. Its purpose is to encourage states to preserve, protect, develop, and, where possible, restore or enhance such valuable natural resources as wetlands, floodplains, estuaries, beaches, dunes, barrier islands, and coral reefs, as well as the fish and wildlife utilizing those habitats. A unique feature of the Act is that participation by states is voluntary. One key provision for encouraging states to participate is the availability of federal financial assistance to any coastal state or territory, including those on the Great Lakes, which is willing to develop and implement a comprehensive coastal management program. Additionally, the Coastal Barrier Resources Act (CBRA) was passed in 1983. This report contains the legislative history and statues associated with each Act. Regulations for implementation and other guidance are included.

  20. Weatherization and Intergovernmental Program - The State Energy Program and the American Recovery and Reinvestment Act

    SciTech Connect

    2010-06-01

    To help the nation weather the ongoing economic downturn and meet key energy goals, the State Energy Program (SEP) will invest $3.1 billion from the American Recovery and Reinvestment Act of 2009 (Recovery Act) for additional grants. These grants do not require matching state funds.

  1. A primer: Social Security Act programs to assist the disabled.

    PubMed

    This summary is designed for those who are unfamiliar with the many current features of federally sponsored disability and health programs under the Social Security Act, including the Social Security Disability Insurance (DI) program, the Supplemental Security Income (SSI) program, Medicare, and Medicaid. It provides an overview of the provisions and operations of the programs. Several SSA resources were consulted in compiling the material: Social Security Handbook (available at http://www.socialsecurity.gov/ OP_Home/handbook/handbook.html); Annual Statistical Supplement to the Social Security Bulletin, 2005 (available at http://www.socialsecurity.gov/policy/docs/statcomps/supplement/2005); Trends in the Social Security and Supplemental Security Income Disability Programs, by John Kearney and L. Scott Muller (available at http://www.socialsecurity.gov/policy/docs/chartbooks/disability trends); and Disability program sections of the Social Security Online Web pages (available at http://www.socialsecurity.gov/disability). This summary is intended to assist in understanding the features of these federal disability and health programs. The descriptions are intended for explanatory purposes and do not provide guidance in administrative or claimant actions.

  2. 78 FR 59751 - Transportation Infrastructure Financing and Innovation Act (TIFIA) Program; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... Office of the Secretary Transportation Infrastructure Financing and Innovation Act (TIFIA) Program... Infrastructure Financing and Innovation Act (TIFIA) program to pay the subsidy cost of supporting Federal credit...: Transportation Infrastructure Financing and Innovation Act program or TIFIA program. OMB Control Number:...

  3. Effect of the Family and Medical Leave Act on the operation of cafeteria plans. Final regulations.

    PubMed

    2001-10-17

    This document contains final regulations relating to cafeteria plans that reflect changes made by the Family and Medical Leave Act of 1993 (Act). The final regulations provide the public with guidance needed to comply with the Act and affect employees who participate in cafeteria plans.

  4. 78 FR 72057 - Rules and Regulations Under the Wool Products Labeling Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... CFR Part 300 Rules and Regulations Under the Wool Products Labeling Act AGENCY: Federal Trade... proposed amendments to the Rules and Regulations under the Wool Products Labeling Act of 1939 (``Wool Rules... Commission issued the Wool Rules to implement the Wool Products Labeling Act of 1939, 15 U.S.C. 68-68j....

  5. 77 FR 29982 - Federal Acquisition Regulation; Submission for OMB Review; Davis Bacon Act-Price Adjustment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... Regulation; Submission for OMB Review; Davis Bacon Act-Price Adjustment (Actual Method) AGENCY: Department of... previously approved information collection requirement concerning the Davis-Bacon Act price adjustment... Bacon Act-Price Adjustment (Actual Method), by any of the following methods: Regulations.gov :...

  6. 75 FR 24862 - Removing Regulations Implementing the Fish and Wildlife Conservation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... Wildlife Conservation Act AGENCY: Fish and Wildlife Service, Interior. ACTION: Proposed rule. SUMMARY: We... and Wildlife Conservation Act of 1980. The Act authorized financial and technical assistance to States... through 86. The regulations at part 83 implement the Fish and Wildlife Conservation Act of 1980 (16...

  7. 75 FR 33752 - Acquisition Regulation: Socioeconomic Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... Parts 919, 922, 923, 924, 925, 926, and 952 RIN 1991-AB87 Acquisition Regulation: Socioeconomic Programs... cause any significant expense for DOE or its contractors. Changes are proposed to DEAR parts 919, 922... remove the ``.'' and adding in its place ``--''. 6. Subpart 922.6 is removed and reserved. This...

  8. 20 CFR 626.4 - Table of contents for the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Table of contents for the Job Training..., DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.4 Table of contents for the Job Training Partnership Act regulations. The table of contents for the regulations...

  9. 29 CFR 2530.200a-2 - Treasury regulations for purposes of the Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Treasury regulations for purposes of the Act. 2530.200a-2... RETIREMENT INCOME SECURITY ACT OF 1974 RULES AND REGULATIONS FOR MINIMUM STANDARDS FOR EMPLOYEE PENSION BENEFIT PLANS Scope and General Provisions § 2530.200a-2 Treasury regulations for purposes of the...

  10. 29 CFR 1903.2 - Posting of notice; availability of the Act, regulations and applicable standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Posting of notice; availability of the Act, regulations and applicable standards. 1903.2 Section 1903.2 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL... § 1903.2 Posting of notice; availability of the Act, regulations and applicable standards. (a)(1)...

  11. 75 FR 58387 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One-Time Reporting, Compensation Requirements AGENCY: Department of Defense (DOD), General Services Administration... Recovery and Reinvestment Act-Reporting Requirements--One Time- Reporting, Compensation...

  12. 75 FR 58389 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One Time Reporting Requirements for Prime Contractors AGENCY: Department of Defense (DOD), General Services... American Recovery and Reinvestment Act-Reporting Requirements--One Time Reporting Requirements for...

  13. 75 FR 58388 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--Quarterly Reporting for Prime Contractors AGENCY: Department of Defense (DOD), General Services Administration (GSA... Recovery and Reinvestment Act--Quarterly Reporting for Prime Contractors. Public comments are...

  14. FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

    PubMed Central

    Zhao, Jonathan C.; Fong, Ka-Wing; Jin, Hong-Jian; Yang, Yeqing A; Kim, Jung; Yu, Jindan

    2016-01-01

    Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2, and AR crosstalk and regulate hormone-dependent gene expression in prostate cancer cells. ChIP-seq analysis revealed that FOXA1 reprograms both AR and GATA2 cistrome by preferably recruiting them to FKHD-containing genomic sites. By contrast, GATA2 is unable to shift AR or FOXA1 to GATA motifs. Rather, GATA2 co-occupancy enhances AR and FOXA1 binding to nearby ARE and FKHD sites, respectively. Similarly, AR increases, but not re-programs, GATA2 and FOXA1 cistromes. Concordantly, GATA2 and AR strongly enhance the transcriptional program of each other, whereas FOXA1 regulates GATA2- and AR-mediated gene expression in a context-dependent manner due to its reprogramming effects. Taken together, our data delineated for the first time the distinct mechanisms by which GATA2 and FOXA1 regulate AR cistrome and suggest that FOXA1 acts upstream of GATA2 and AR in determining hormone-dependent gene expression in prostate cancer. PMID:26751772

  15. PDCD10/CCM3 acts downstream of {gamma}-protocadherins to regulate neuronal survival.

    PubMed

    Lin, Chengyi; Meng, Shuxia; Zhu, Tina; Wang, Xiaozhong

    2010-12-31

    γ-Protocadherins (PCDH-γ) regulate neuronal survival in the vertebrate central nervous system. The molecular mechanisms of how PCDH-γ mediates this function are still not understood. In this study, we show that through their common cytoplasmic domain, different PCDH-γ isoforms interact with an intracellular adaptor protein named PDCD10 (programmed cell death 10). PDCD10 is also known as CCM3, a causative genetic defect for cerebral cavernous malformations in humans. Using RNAi-mediated knockdown, we demonstrate that PDCD10 is required for the occurrence of apoptosis upon PCDH-γ depletion in developing chicken spinal neurons. Moreover, overexpression of PDCD10 is sufficient to induce neuronal apoptosis. Taken together, our data reveal a novel function for PDCD10/CCM3, acting as a critical regulator of neuronal survival during development.

  16. Methods and Challenges Related to Implementing the New National School Lunch Program Regulations in Indiana

    ERIC Educational Resources Information Center

    Thiagarajah, Krisha; Getty, Victoria M.; Johnson, Hattie L.; Case, Megan; Herr, Susan J.

    2015-01-01

    Purpose/Objectives: The Healthy, Hunger-Free Kids Act of 2010 resulted in updated National School Lunch Program (NSLP) regulations from the U.S. Department of Agriculture. The purpose of this research was to investigate the approaches used by school foodservice managers and directors in Indiana in complying with the new regulations and to identify…

  17. 77 FR 19455 - Regulations Implementing the Byrd Amendments to the Black Lung Benefits Act: Determining Coal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ...This document contains proposed regulations implementing amendments to the Black Lung Benefits Act (BLBA or Act) made by the Patient Protection and Affordable Care Act (ACA). The ACA amended the BLBA in two ways. First, it revived a rebuttable presumption of total disability or death due to pneumoconiosis for certain claims. Second, it reinstituted derivative entitlement to benefits for......

  18. 76 FR 24027 - Federal Acquisition Regulation; Information Collection; Buy American Act Certificate

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... Regulation; Information Collection; Buy American Act Certificate AGENCY: Department of Defense (DOD), General... previously approved information collection requirement concerning the Buy American Act certificate. Public...-mail cecelia.davis@gsa.gov . SUPPLEMENTARY INFORMATION: A. Purpose The Buy American Act requires...

  19. 75 FR 14547 - Tribal Consultation on Draft Buy Indian Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of Indian Affairs 48 CFR Chapter 14 RIN 1076-AE95 Tribal Consultation on Draft Buy Indian Act... comments concerning draft regulations to implement the Buy Indian Act. See the SUPPLEMENTARY INFORMATION... implementation of the Buy Indian Act, 25 U.S.C. 47, which provides authority to set aside procurement...

  20. 77 FR 13328 - Federal Acquisition Regulation; Information Collection; Davis Bacon Act-Price Adjustment (Actual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... Regulation; Information Collection; Davis Bacon Act--Price Adjustment (Actual Method) AGENCY: Department of... previously approved information collection requirement concerning the Davis-Bacon Act price adjustment... comments identified by Information Collection 9000- 0154, Davis Bacon Act--Price Adjustment (Actual...

  1. 75 FR 3665 - Regulations under the Comprehensive Smokeless Tobacco Health Education Act; Termination of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ...The Federal Trade Commission (``FTC'' or ``Commission'') has terminated its rulemaking concerning a proposed amendment to its regulations (``smokeless tobacco regulations''), , implementing the Comprehensive Smokeless Tobacco Health Education Act of 1986 (``Smokeless Tobacco Act''). The proposed amendment expressly provided that sponsored racing vehicles and other event-related objects that......

  2. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Format of the Job Training Partnership Act regulations. 626.2 Section 626.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the...

  3. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Format of the Job Training Partnership Act regulations. 626.2 Section 626.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the...

  4. 76 FR 82117 - Regulations Implementing the Longshore and Harbor Workers' Compensation Act: Recreational Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ...This final rule contains regulations implementing amendments to the Longshore and Harbor Workers' Compensation Act (LHWCA) by the American Recovery and Reinvestment Act of 2009 (ARRA), relating to the exclusion of certain recreational-vessel workers from the LHWCA's definition of ``employee.'' These regulations clarify both the definition of ``recreational vessel'' and those circumstances......

  5. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Format of the Job Training Partnership Act regulations. 626.2 Section 626.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the...

  6. 78 FR 41835 - Inflation Adjustments to the Price-Anderson Act Financial Protection Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... Federal Regulations is sold by the Superintendent of Documents. #0;Prices of new books are listed in the... 3150-AJ25 Inflation Adjustments to the Price-Anderson Act Financial Protection Regulations AGENCY: Nuclear Regulatory Commission. ACTION: Final rule. SUMMARY: The Atomic Energy Act of 1954, as amended...

  7. 77 FR 234 - Rules and Regulations Under the Textile Fiber Products Identification Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ...; ] FEDERAL TRADE COMMISSION 16 CFR Part 303 Rules and Regulations Under the Textile Fiber Products... Rules and Regulations under the Textile Fiber Products Identification Act (``Textile Rules'').\\1\\ The... the Textile Rules to implement the Textile Fiber Products Identification Act, 15 U.S.C. 70-70k....

  8. 20 CFR 626.3 - Purpose, scope, and applicability of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Purpose, scope, and applicability of the Job Training Partnership Act regulations. 626.3 Section 626.3 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.3 Purpose, scope, and...

  9. 20 CFR 626.3 - Purpose, scope, and applicability of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Purpose, scope, and applicability of the Job Training Partnership Act regulations. 626.3 Section 626.3 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.3 Purpose, scope, and...

  10. 20 CFR 626.3 - Purpose, scope, and applicability of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Purpose, scope, and applicability of the Job Training Partnership Act regulations. 626.3 Section 626.3 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.3 Purpose, scope, and...

  11. 75 FR 41370 - Regulations Implementing the Freedom of Information Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ..., 121 Stat. 2524. The OPEN Government Act amended various FOIA administrative procedures, such as when... procedural rules, final Commission decisions since 1972, final administrative law judges' decisions since 1993, administrative law judges' decisions pending Commission review, strategic plans,...

  12. 76 FR 78121 - Fair Debt Collection Practices Act (Regulation F)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Financial Protection (Bureau), effective July 21, 2011.\\4\\ See sections 1061 and 1089 of the Dodd-Frank Act... Consumer Financial Protection Act of 2010. Public Law 111-203, section 1089(4); 15 U.S.C.1692l(d). II... Law 111-203, section 1089(1); 15 U.S.C. 1692o. B. Authority To Issue an Interim Final Rule...

  13. FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression.

    PubMed

    Zhao, J C; Fong, K-W; Jin, H-J; Yang, Y A; Kim, J; Yu, J

    2016-08-18

    Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2 and AR crosstalk and regulate hormone-dependent gene expression in prostate cancer cells. Chromatin immunoprecipitation sequencing analysis revealed that FOXA1 reprograms both AR and GATA2 cistrome by preferably recruiting them to FKHD-containing genomic sites. By contrast, GATA2 is unable to shift AR or FOXA1 to GATA motifs. Rather, GATA2 co-occupancy enhances AR and FOXA1 binding to nearby ARE and FKHD sites, respectively. Similarly, AR increases, but not reprograms, GATA2 and FOXA1 cistromes. Concordantly, GATA2 and AR strongly enhance the transcriptional program of each other, whereas FOXA1 regulates GATA2- and AR-mediated gene expression in a context-dependent manner due to its reprogramming effects. Taken together, our data delineated for the first time the distinct mechanisms by which GATA2 and FOXA1 regulate AR cistrome and suggest that FOXA1 acts upstream of GATA2 and AR in determining hormone-dependent gene expression in prostate cancer.

  14. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false EPA review of State Clean Air Act... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  15. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false EPA review of State Clean Air Act... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  16. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false EPA review of State Clean Air Act... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  17. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false EPA review of State Clean Air Act... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  18. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FEDERAL ASSISTANCE TRIBAL CLEAN AIR ACT AUTHORITY Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be disapproved because of failure to... 40 Protection of Environment 1 2010-07-01 2010-07-01 false EPA review of State Clean Air...

  19. 76 FR 18375 - Small Business Jobs Act: Eligible Loans for 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... ADMINISTRATION 13 CFR Part 120 Small Business Jobs Act: Eligible Loans for 504 Loan Program Debt Refinancing... Small Business Jobs Act. DATES: Effective Date: This document is effective April 4, 2011. FOR FURTHER... the Small Business Jobs Act (Jobs Act), Public Law 111-240, 124 Stat. 2504, only loans that...

  20. 77 FR 17143 - Medicaid Program; Eligiblity Changes Under the Affordable Care Act of 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ...This final rule implements several provisions of the Patient Protection and Affordable Care Act of 2010 and the Health Care and Education Reconciliation Act of 2010 (collectively referred to as the Affordable Care Act). The Affordable Care Act expands access to health insurance coverage through improvements to the Medicaid and Children's Health Insurance (CHIP) programs, the establishment of......

  1. ACT-CCREC Core Research Program: Study Questions and Design. ACT Working Paper Series. WP-2015-01

    ERIC Educational Resources Information Center

    Cruce, Ty M.

    2015-01-01

    This report provides a non-technical overview of the guiding research questions and research design for the ACT-led core research program conducted on behalf of the GEAR UP College and Career Readiness Evaluation Consortium (CCREC). The core research program is a longitudinal study of the effectiveness of 14 GEAR UP state grants on the academic…

  2. 78 FR 43261 - Transportation Infrastructure Financing and Innovation Act (TIFIA) Program; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... Office of the Secretary of Transportation Transportation Infrastructure Financing and Innovation Act... for the Transportation Infrastructure Financing and Innovation Act (TIFIA) program to pay the subsidy....gov . SUPPLEMENTARY INFORMATION: Title: Transportation Infrastructure Financing and Innovation...

  3. Risk Management Programs under Clean Air Act Section 112(r): Guidance for Implementing Agencies

    EPA Pesticide Factsheets

    Accidental release prevention programs under section 112(r) of the Clean Air Act (CAA) are related to and build on activities under the Emergency Planning and Community Right-to-Know Act, and Occupational Safety and Health Administration standards.

  4. 75 FR 12226 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ...; the Academic Competitiveness Grant Program; the National Science and Mathematics Access to Retain... Federal Family Education Loan Program; the William D. Ford Federal Direct Loan Program; the...

  5. 78 FR 32595 - Revision of Freedom of Information Act Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... practices with respect to FOIA. Finally, the rule would use current cost figures in calculating and charging... enacted by the OPEN Government Act of 2007, reflect developments in the case law, and include current cost... increased from that provided for under current Sec. 15.110(c). Duplication costs for media copies would...

  6. 75 FR 22320 - Regulations Implementing the Freedom of Information Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... deletion of materials under the FOIA on the responsive record. Second, as a result of the Chief FOIA...) to reflect the more detailed description of those duties set forth under the OPEN Government Act. 5 U... forth in paragraph (g) to include, where technically feasible, marking the exemption under which...

  7. 34 CFR 460.2 - What programs are authorized by the Adult Education Act?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS § 460.2 What programs are authorized by the Adult Education Act? The following programs are...

  8. 34 CFR 460.2 - What programs are authorized by the Adult Education Act?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS § 460.2 What programs are authorized by the Adult Education Act? The following programs are...

  9. 34 CFR 460.2 - What programs are authorized by the Adult Education Act?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS § 460.2 What programs are authorized by the Adult Education Act? The following programs are...

  10. 34 CFR 460.2 - What programs are authorized by the Adult Education Act?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS § 460.2 What programs are authorized by the Adult Education Act? The following programs are...

  11. Atomic Energy Act and Related Legislation. Environmental Guidance Program Reference Book: Revision 6

    SciTech Connect

    Not Available

    1992-09-01

    This report presents information related to the Atomic Energy Act and related legislation. Sections are presented pertaining to legislative history and statutes, implementing regulations, and updates.

  12. 75 FR 38684 - Federal Acquisition Regulation; FAR Case 2010-008, Recovery Act Subcontract Reporting Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... regulations it believes are necessary. OMB has determined that obtaining publicly reported jobs information at... Regulation; FAR Case 2010-008, Recovery Act Subcontract Reporting Procedures AGENCIES: Department of Defense... Defense Acquisition Regulations Council (Councils) have agreed on an interim rule amending the...

  13. 25 CFR 101.10 - Federal Reserve Regulation Z and Fair Credit Reporting Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Federal Reserve Regulation Z and Fair Credit Reporting Act... ACTIVITIES LOANS TO INDIANS FROM THE REVOLVING LOAN FUND § 101.10 Federal Reserve Regulation Z and Fair... subject to the provisions of Federal Reserve Regulation Z (Truth In Lending, 12 CFR part 226; Pub. L....

  14. 78 FR 8963 - Update of Existing Privacy Act-NASA Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ... SPACE ADMINISTRATION 14 CFR Part 1212 RIN 2700-AD86 Update of Existing Privacy Act--NASA Regulations... document contains corrections to the final regulations (NASA-2012-0005), which were published in the... Jennings, 202-358-0819. SUPPLEMENTARY INFORMATION: Background NASA's final regulations that published...

  15. Recovery Act - Sustainable Transportation: Advanced Electric Drive Vehicle Education Program

    SciTech Connect

    Caille, Gary

    2013-12-13

    The collective goals of this effort include: 1) reach all facets of this society with education regarding electric vehicles (EV) and plug–in hybrid electric vehicles (PHEV), 2) prepare a workforce to service these advanced vehicles, 3) create web–based learning at an unparalleled level, 4) educate secondary school students to prepare for their future and 5) train the next generation of professional engineers regarding electric vehicles. The Team provided an integrated approach combining secondary schools, community colleges, four–year colleges and community outreach to provide a consistent message (Figure 1). Colorado State University Ventures (CSUV), as the prime contractor, plays a key program management and co–ordination role. CSUV is an affiliate of Colorado State University (CSU) and is a separate 501(c)(3) company. The Team consists of CSUV acting as the prime contractor subcontracted to Arapahoe Community College (ACC), CSU, Motion Reality Inc. (MRI), Georgia Institute of Technology (Georgia Tech) and Ricardo. Collaborators are Douglas County Educational Foundation/School District and Gooru (www.goorulearning.org), a nonprofit web–based learning resource and Google spin–off.

  16. 75 FR 41788 - Amendment to the Bank Secrecy Act Regulations-Definitions and Other Regulations Relating to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Financial Crimes Enforcement Network 31 CFR Part 103 RIN 1506-AB07 Amendment to the Bank Secrecy Act Regulations--Definitions and Other Regulations Relating to Prepaid Access AGENCY: Financial Crimes Enforcement.... Steele, Deputy Director, Financial Crimes Enforcement Network. BILLING CODE 4810-02-P...

  17. 76 FR 30978 - Employment and Training Administration Program Year (PY) 2011 Workforce Investment Act (WIA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Workforce Investment Act (WIA) Section 167, National Farmworker Jobs Program (NFJP) Allocations AGENCY... PY 2011 for the WIA Title I Section 167 National Farmworker Jobs Program (NFJP) program. The NFJP... Applications (SGA) for the National Farmworker Jobs Program and the National Farmworker Jobs Program...

  18. 75 FR 32480 - Funding Opportunity: Affordable Care Act Medicare Beneficiary Outreach and Assistance Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ... Outreach and Assistance Program Funding for Title VI Native American Programs Purpose of Notice... Medicare Beneficiary Outreach and Assistance Program Funding for Title VI Native American Programs... Older Americans Act Title VI Native American program awardee. The purpose of these grants will be...

  19. 77 FR 56592 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... language and structure of the FOIA regulations in order to improve the Department's FOIA performance. More... detailed information about Department procedures for making FOIA requests and descriptions of the types of... possible about the specific records or types of records that you are seeking. This will assist the...

  20. Brightening up: the effect of the Physician Payment Sunshine Act on existing regulation of pharmaceutical marketing.

    PubMed

    Gorlach, Igor; Pham-Kanter, Genevieve

    2013-01-01

    With the passage of the Physician Payment Sunshine Act as part of the federal health care reform law, pharmaceutical manufacturers are now required to disclose a wide range of payments made by manufacturers to physicians. We review current state regulation of pharmaceutical marketing and consider how the federal sunshine provision will affect existing marketing regulation. We analyze the legal and practical implications of the Physician Payment Sunshine Act.

  1. 78 FR 54650 - Federal Acquisition Regulation; Information Collection American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... Regulation; Information Collection American Recovery and Reinvestment Act-Reporting Requirements--One-Time... requirement concerning the American Recovery and Reinvestment Act-Reporting Requirements--One Time Reporting... Requirements-- One Time Reporting for First-tier Subcontractors, by any of the following methods:...

  2. 78 FR 54648 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... Regulation; Information Collection; American Recovery and Reinvestment Act--Reporting Requirements--One-Time... requirement concerning the American Recovery and Reinvestment Act--Reporting Requirements--One Time-Reporting... Requirements-- One Time-Reporting, Compensation Requirements, by any of the following methods:...

  3. 78 FR 57808 - Rules and Regulations Under the Wool Products Labeling Act of 1939

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ...Based on comments received in response to its Advance Notice of Proposed Rulemaking, the Federal Trade Commission (the ``Commission'' or ``FTC'') proposes amending its rules and regulations under the Wool Products Labeling Act of 1939 (``Wool Rules'' or ``Rules'') to: conform to the requirements of the Wool Suit Fabric Labeling Fairness and International Standards Conforming Act, which revised......

  4. 75 FR 58390 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One-Time Reporting for First-Tier Subcontractors AGENCY: Department of Defense (DOD), General Services Administration... Reinvestment Act-Reporting Requirements--One-Time Reporting for First-Tier Subcontractors. Public comments...

  5. 76 FR 16977 - Regulations To Implement the Equal Employment Provisions of the Americans With Disabilities Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-25

    ...The Equal Employment Opportunity Commission (the Commission or the EEOC) issues its final revised Americans with Disabilities Act (ADA) regulations and accompanying interpretive guidance in order to implement the ADA Amendments Act of 2008. The Commission is responsible for enforcement of title I of the ADA, as amended, which prohibits employment discrimination on the basis of disability.......

  6. 78 FR 40196 - National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... SPACE ADMINISTRATION National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research... the Final Environmental Impact Statement (FEIS) for the NASA Sounding Rockets Program (SRP) at Poker... government agencies, and educational institutions have conducted suborbital rocket launches from the...

  7. The National Childhood Vaccine Injury Act. The National Vaccine Injury Compensation Program.

    ERIC Educational Resources Information Center

    Clark, Susan G.

    1995-01-01

    Reviews the National Childhood Vaccine Injury Act and the National Vaccine Injury Compensation Program to specifically address the injuries sustained through vaccination. The compensation program allows special education for children permanently injured by vaccines. Analyzes selected cases. (57 footnotes) (MLF)

  8. BACT analysis under the Clean Air Act's PCD program

    SciTech Connect

    Simms, P.; Walke, J.

    2006-11-15

    Before a company may build a new major industrial source of air pollution, or make modifications to an existing major source in the USA it must apply for and receive a Clean Air Act (CAA) Prevention of Significant Deterioration (PSD) permit. State environmental agencies typically issue such permits, either under state law or by exercising delegated authority to implement the federal PSD program. To fully comply with the CAA, the emissions limits identified as BACT must incorporate consideration of more than just add-on emissions control technology, they must also reflect appropriate considerations of fuel quality (e.g. low-sulfur coal) and process changes (e.g. advanced combustion techniques) as a means of controlling emissions, and must consider the other environmental and public welfare benefits of the identified emissions control options. Several states including New Mexico and Illinois have already determined that innovated technologies, such as Integrated Gasification Combined Cycle (IGCC), must be considered in connection with the BACT analysis for new coal-fired power plants. Even the notion that BACT is categorically limited in scope to the general type of facility proposed is contrary to EPA precedent. For example, the Environmental Appeals Board (EAB) has explained that permitting authorities retain the discretion under the definition of BACT to require dramatically different facility designs (e.g. a natural gas plant instead of a coal-fired power plant). The best advice for any permit applicant is to include in the BACT analysis a careful and honest examination of better performing alternative processes and/or innovative combustion techniques and to aggressively pursue such options wherever feasible. 17 refs.

  9. 78 FR 32364 - Magnuson-Stevens Act Provisions; Interjurisdictional Fisheries Act; Disaster Assistance Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... Management Act (MSA) and the Interjurisdictional Fisheries Act (IFA), NMFS (on behalf of the Secretary of... disaster assistance provisions of the MSA and the IFA through rulemaking and, thereby, ensure consistency... provisions of section 312(a) and 315 of the MSA and sections 308(b) and 308(d) of the IFA. Authority: 16...

  10. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... Transparency Act reporting requirements; and (2) That either: (i) Is issued on or after the effective date...

  11. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... are subject to Transparency Act reporting requirements; and (2) That either: (i) Is issued on or...

  12. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... are subject to Transparency Act reporting requirements; and (2) That either: (i) Is issued on or...

  13. 2 CFR 170.200 - Requirements for program announcements, regulations, and application instructions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Requirements for program announcements, regulations, and application instructions. 170.200 Section 170.200 Grants and Agreements Office of Management... Act reporting requirements; and (2) That either: (i) Is issued on or after the effective date of...

  14. 78 FR 19261 - Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... AGENCY Safe Drinking Water Act Sole Source Aquifer Program; Designation of Bainbridge Island, Washington.... SUMMARY: Notice is hereby given that pursuant to Section 1424(e) of the Safe Drinking Water Act, the... Section 1424(e) of the Safe Drinking Water Act (42 U.S.C. 300h3(e), Public Law 93-523 of December......

  15. 76 FR 63151 - Small Business Jobs Act: 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... Small Business Jobs Act: 504 Loan Program Debt Refinancing AGENCY: U.S. Small Business Administration... the Small Business Jobs Act of 2010, which authorizes projects approved for financing under Title V of... is not adopting this recommendation as the Small Business Jobs Act expressly provides that...

  16. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  17. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  18. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  19. 75 FR 75469 - Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-03

    ... Children's Health Insurance Program Reauthorization Act of 2009 (Pub. L. 111-3) amended title Xl of the... enacted the Children's Health Insurance Program Reauthorization Act (CHIPRA) of 2009 (Pub. L. 111-3... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  20. [Aliens Act regulations and consequences of inability to travel].

    PubMed

    Wollenweber, H-M

    2003-12-01

    The question as to whether a foreign national is (un)able to travel or not is often in the foreground of the decision-making process concerning a possible termination of their stay in the Federal Republic of Germany. Authorities responsible for aliens and administrative courts often require accredited medical reports to be able to decide whether inability to travel is actually the case. There are no clear legal criteria with regard to the definition of this term and an explicit provision by law is also missing. In cases where the decision has been made against inability to travel (i.e. a person is said to be able to travel), there may be considerable risks for the person concerned. Where the decision has been made in favour of inability to travel (i.e. the person is said to be unable to travel), a protective system based on the Aliens' Act takes effect. This article gives an overview of the legal consequences arising from a determined inability to travel; the legal difficulties with regard to the definition of this term; and the requirements to be made concerning clarity of a prognosis regarding possible risks. The pertinent legislation as well as opinions expressed in expert literature are presented.

  1. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  2. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  3. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  4. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  5. 77 FR 38717 - Updating Regulations Issued Under the Fair Labor Standards Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Wage and Hour Division 29 CFR Parts 531 and 553 Updating Regulations Issued Under the Fair Labor Standards Act CFR Correction In Title 29 of the Code of Federal Regulations, Parts 500 to 899, revised as of July...

  6. Learn about the EPA's Federal Technology Transfer Act Program

    EPA Pesticide Factsheets

    This act allows sharing Agency knowledge and expertise with outside partners through collaborative agreements and licensing. Potential partners can take advantage of opportunities to create or further develop solutions to environmental problems.

  7. 77 FR 12930 - Federal Acquisition Regulation: Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... 9000-AL88 Federal Acquisition Regulation: Socioeconomic Program Parity AGENCY: Department of Defense... parity and that contracting officers may exercise discretion when determining whether an acquisition will... Socioeconomic Programs Comment: One respondent noted that socioeconomic parity could not be implemented...

  8. Establishing a regulatory framework for a RCRA (Resource, Conservation, and Recovery Act) corrective action program

    SciTech Connect

    Krueger, J.W.

    1989-01-01

    Recently, the environmental community has become keenly aware of problems associated with integration of the demanding regulations that apply to environmental restoration activities. One can not attend an EPA-sponsored conference on Superfund without distracting questions concerning the Resource, Conservation, and Recovery Act (RCRA) and the applicability of the National Contingency Plan (NCP) to sites that do not qualify for the National Priorities List (NPL). In particular, the US Department of Energy (DOE) has been greatly criticized for its inability to define a comprehensive approach for cleaning up its hazardous waste sites. This article presents two decision flowcharts designed to resolve some of this confusion for DOE. The RCRA/CERCLA Integration Diagram can help the environmental manager determine which law applies and under what conditions, and the RCRA Corrective Action Decision Flowchart can guide the manager in determining which specific sections of RCRA apply to a RCRA-lead environmental restoration program. 13 refs.

  9. Title I--improving the academic achievement of the disadvantaged; Individuals with Disabilities Education Act (IDEA)--assistance to states for the education of children with disabilities. Final regulations.

    PubMed

    2007-04-09

    The Secretary amends the regulations governing programs administered under Title I of the Elementary and Secondary Education Act of 1965 (ESEA), as amended by the No Child Left Behind Act of 2001 (NCLB) (referred to in these regulations as the Title I program) and the regulations governing programs under Part B of the Individuals with Disabilities Education Act (IDEA) (referred to in these regulations as the IDEA program). These regulations provide States with additional flexibility regarding State, local educational agency (LEA), and school accountability for the achievement of a small group of students with disabilities whose progress is such that, even after receiving appropriate instruction, including special education and related services designed to address the students' individual needs, the students' individualized education program (IEP) teams (IEP Teams) are reasonably certain that the students will not achieve grade-level proficiency within the year covered by the students' IEPs.

  10. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program,...

  11. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program,...

  12. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program,...

  13. The Americans with Disabilities Act and Child Care Programs.

    ERIC Educational Resources Information Center

    Pardeck, John T.

    1997-01-01

    Discusses the major components of the Americans with Disabilities Act of 1990 applicable to day care facilities. Offers guidelines for admitting disabled children, and for determining whether an accommodation is reasonable or an unreasonable burden. Considers an ADA case involving discrimination against a diabetic child for insights into the…

  14. Environmental Guidance Program Reference Book: American Indian Religious Freedom Act

    SciTech Connect

    Not Available

    1987-11-01

    This Reference Book contains a copy of the American Indian Religious Freedom Act and guidance for DOE compliance with the statute. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically.

  15. A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size

    PubMed Central

    Kaplan, Daniel D.; Zimmermann, Gregor; Suyama, Kaye; Meyer, Tobias; Scott, Matthew P.

    2008-01-01

    Growth and body size are regulated by the CNS, integrating the genetic developmental program with assessments of an animal’s current energy state and environmental conditions. CNS decisions are transmitted to all cells of the animal by insulin/insulin-like signals. The molecular biology of the CNS growth control system has remained, for the most part, elusive. Here we identify NS3, a Drosophila nucleostemin family GTPase, as a powerful regulator of body size. ns3 mutants reach <60% of normal size and have fewer and smaller cells, but exhibit normal body proportions. NS3 does not act cell-autonomously, but instead acts at a distance to control growth. Rescue experiments were performed by expressing wild-type ns3 in many different cells of ns3 mutants. Restoring NS3 to only 106 serotonergic neurons rescued global growth defects. These neurons are closely apposed with those of insulin-producing neurons, suggesting possible communication between the two neuronal systems. In the brains of ns3 mutants, excess serotonin and insulin accumulate, while peripheral insulin pathway activation is low. Peripheral insulin pathway activation rescues the growth defects of ns3 mutants. The findings suggest that NS3 acts in serotonergic neurons to regulate insulin signaling and thus exert global growth control. PMID:18628395

  16. Multivariate Analyses of Urban Community College Student Performance on the ACT College Outcomes Measures Program Test.

    ERIC Educational Resources Information Center

    Kitabchi, Gloria

    This study examined the relationship and relative importance of selected variables to successful performance of urban community college students on the American College Testing Program (ACT) College Outcome Measures Program (COMP). The importance of age, race, gender, type of degree, program or major category, admissions criteria and ACT…

  17. 76 FR 56744 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, Department of Defense (DoD). ACTION: Notice of a computer matching program. SUMMARY... advance notice of any proposed or revised computer matching program by the matching agency for...

  18. 77 FR 34941 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, DoD. ACTION: Notice of a computer matching program. SUMMARY: Subsection (e)(12) of the... proposed or revised computer matching program by the matching agency for public comment. The DoD, as...

  19. 76 FR 77811 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-14

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, Department of Defense (DoD). ACTION: Notice of a Computer Matching Program. SUMMARY... advance notice of any proposed or revised computer matching program by the matching agency for...

  20. 77 FR 13388 - Treasury Inspector General for Tax Administration; Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... Treasury Inspector General for Tax Administration; Privacy Act of 1974: Computer Matching Program AGENCY... conduct of TIGTA's computer matching program. DATES: Effective Date: April 5, 2012. ADDRESSES: Comments or... Administration, (202) 622-4068. SUPPLEMENTARY INFORMATION: TIGTA's computer matching program assists in...

  1. 75 FR 8311 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, DoD. ACTION: Notice of a computer matching program. SUMMARY: Subsection (e)(12) of the... proposed or revised computer matching program by the matching agency for public comment. The DoD, as...

  2. 76 FR 50460 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, Department of Defense (DoD). ACTION: Notice of a Computer Matching Program. SUMMARY... advance notice of any proposed or revised computer matching program by the matching agency for...

  3. 78 FR 73851 - Privacy Act of 1974; Notice of a Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ... of the Secretary Privacy Act of 1974; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, DoD. ACTION: Notice of a computer matching program. SUMMARY: Subsection (e)(12) of the... proposed or revised computer matching program by the matching agency for public comment. The Department...

  4. Federal Register Notice: State Authorization To Regulate the Hazardous Components of Radioactive Mixed Wastes Under the Resource Conservation and Recovery Act

    EPA Pesticide Factsheets

    The Environmental Protection Agency (EPA) is today publishing a notice that in order to obtain and maintain authorization to administer and enforce a hazardous waste program pursuant to Subtitle C of the Resource Conservation and Recovery Act (RCRA), States must have authority to regulate the hazardous components of 'radioactive mixed wastes.

  5. Fact Sheet on the History of the Resource Conservation and Recovery Act (RCRA) Corrective Action Program

    EPA Pesticide Factsheets

    This fact sheet provides an overview of the main events that have shaped the current RCRA Corrective Action Program. It also provides a brief history of the statutory authorities, regulations, and policy that form the framework for the program.

  6. Child support enforcement program: paternity establishment and revision of child support enforcement program and audit regulations--Office of Child Support Enforcement. Final rule.

    PubMed

    1994-12-23

    This final rule contains provisions regarding both paternity establishment and the audit. The paternity establishment provisions implement the requirements of section 13721 of the Omnibus Budget Reconciliation Act of 1993 (OBRA '93) signed by the President on August 10, 1993, which amends title IV-D of the Social Security Act (the Act). These provisions require States to adopt procedures for a simple civil process for the voluntary acknowledgement of paternity, including early paternity establishment programs in hospitals. For paternity cases that remain contested, the statutory provisions require States to adopt a variety of procedures designed to streamline the paternity establishment process. These include the use of default orders, a presumption of paternity based on genetic test results, conditions for admission of genetic test results as evidence, and expedited decision-making processes for paternity cases in which title IV-D services are being provided. In addition, this final regulation amends the Child Support Enforcement program regulations governing the audit of State Child Support Enforcement (IV-D) programs and the imposition of financial penalties for failure to substantially comply with the requirements of title IV-D of the Act. This regulation specifies how audits will evaluate State compliance with the requirements set forth in title IV-D of the Act and Federal regulations, including requirements resulting from the Family Support Act of 1988 and section 13721 of OBRA '93. This final regulation also redefines substantial compliance to place greater focus on performance and streamlines Part 305 by removing unnecessary sections.

  7. 78 FR 18344 - Federal Acquisition Regulation; Submission for OMB Review; Buy American Act-Free Trade Agreements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Regulation; Submission for OMB Review; Buy American Act--Free Trade Agreements--Israeli Trade Act Certificate... previously approved information collection requirement concerning the Buy American Act--Free Trade Agreements... comments identified by Information Collection 9000- 0130, Buy American Act--Free Trade...

  8. Notification: EPA Oversight of Delegated State Resource Conservation and Recovery Act Programs

    EPA Pesticide Factsheets

    Project #OPE-FY16-0033, September 19, 2016. The EPA OIG plans to begin preliminary research on the EPA's oversight of authorized state hazardous waste programs that fall under the Resource Conservation and Recovery Act.

  9. 76 FR 21741 - Twenty-First Century Communications and Video Programming Accessibility Act; Announcement of Town...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... distribution program, and TRS contributions by VoIP providers, were deemed oral ex parte presentations in the... that the Commission has taken to obtain public feedback as it implements the Act. The Town Hall...

  10. 77 FR 61642 - National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... addressed to Joshua Bundick, Manager, Poker Flat Research Range EIS, NASA Goddard Space Flight Center's... SPACE ADMINISTRATION National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of availability...

  11. Terms and conditions for nonprofits in the Diesel Emissions Reduction Act (DERA) National Program

    EPA Pesticide Factsheets

    EPA has determined that all construction, alteration, and repair activity involving the following Diesel Emissions Reduction Act (DERA) projects is subject to DB. Use this T&C for nonprofits in the DERA National Program.

  12. 77 FR 74913 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... From the Federal Register Online via the Government Publishing Office SOCIAL SECURITY ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA)/Office of Personnel Management (OPM))--Match Number 1307 AGENCY: Social Security Administration....

  13. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  14. 20 CFR 667.300 - What are the reporting requirements for Workforce Investment Act programs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false What are the reporting requirements for Workforce Investment Act programs? 667.300 Section 667.300 Employees' Benefits EMPLOYMENT AND TRAINING... INVESTMENT ACT Reporting Requirements § 667.300 What are the reporting requirements for Workforce...

  15. 75 FR 69151 - Small Business Jobs Act: 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... ADMINISTRATION Small Business Jobs Act: 504 Loan Program Debt Refinancing AGENCY: U.S. Small Business... notice to announce the location, date, time and agenda for a meeting regarding the Small Business Jobs... Business Jobs Act (Pub. L. 111-240). The purpose of the meeting is for the SBA Office of...

  16. 78 FR 46256 - Security Program, Report of Suspected Crimes, Suspicious Transactions, Catastrophic Acts and Bank...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... From the Federal Register Online via the Government Publishing Office NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Part 748 Security Program, Report of Suspected Crimes, Suspicious Transactions, Catastrophic Acts and Bank Secrecy Act Compliance CFR Correction In Title 12 of the Code of Federal...

  17. Ten Years of the Workforce Investment Act (WIA): Interpreting the Research on WIA and Related Programs

    ERIC Educational Resources Information Center

    Decker, Paul T.; Berk, Jillian A.

    2011-01-01

    In 1998, President Clinton signed the federal Workforce Investment Act (WIA). Implemented in 2000, WIA replaced the Job Partnership Training Act (JTPA) as the primary federal job training program. Congress viewed WIA as a way to end "business as usual" in the workforce investment system. WIA aimed to transform the employment and training…

  18. LBR-2 Earth stations for the ACTS program

    NASA Technical Reports Server (NTRS)

    Oreilly, Michael; Jirberg, Russell; Spisz, Ernie

    1990-01-01

    The Low Burst Rate-2 (LBR-2) earth station being developed for NASA's Advanced Communications Technology Satellite (ACTS) is described. The LBR-2 is one of two earth station types that operate through the satellite's baseband processor. The LBR-2 is a small earth terminal (VSAT)-like earth station that is easily sited on a user's premises, and provides up to 1.792 megabits per second (MBPS) of voice, video, and data communications. Addressed here is the design of the antenna, the rf subsystems, the digital processing equipment, and the user interface equipment.

  19. Harvesting Social Change: A Peace Education Program in Three Acts

    ERIC Educational Resources Information Center

    Cann, Colette N.

    2012-01-01

    This article narrates the story of how a peace education program, over the course of a year, shifts from a more traditional form of peace education as conflict resolution skill building to a critical form of peace education. The path of this journey was neither straight nor direct; rather it meandered through an iteration of itself that actually…

  20. 77 FR 33547 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Centers for Medicare and Medicaid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Centers for Medicare and Medicaid... of the Privacy Act, as amended, this notice announces a new computer matching program that we will... Privacy Act We have taken action to ensure that all of our computer matching programs comply with...

  1. 76 FR 75799 - General Administrative Regulations; Mutual Consent Cancellation; Food Security Act of 1985...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... Consent Cancellation; Food Security Act of 1985, Implementation; Denial of Benefits; and Ineligibility for... remove Subpart C--General Administrative Regulations; Mutual Consent Cancellation and Subpart F--Food... quality of the human environment, health, or safety. Therefore, neither an Environmental Assessment nor...

  2. 78 FR 70515 - Petition To Promulgate Standards for Bears Under the Animal Welfare Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... Promulgate Standards for Bears Under the Animal Welfare Act Regulations AGENCY: Animal and Plant Health... transportation of all species of bears held in captivity except polar bears, for which there are already... pigs and hamsters, rabbits, nonhuman primates, and marine mammals (including polar bears), and...

  3. 77 FR 60620 - Update of Existing Privacy Act-NASA Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... From the Federal Register Online via the Government Publishing Office NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 14 CFR Part 1212 RIN 2700-AD86 Update of Existing Privacy Act--NASA Regulations AGENCY: National Aeronautics and Space Administration. ACTION: Direct final rule. SUMMARY: This...

  4. 76 FR 10234 - Amendment to the Bank Secrecy Act Regulations-Reports of Foreign Financial Accounts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ...FinCEN is issuing this final rule to amend the Bank Secrecy Act (BSA) regulations regarding reports of foreign financial accounts. The rule addresses the scope of the persons that are required to file reports of foreign financial accounts. The rule further specifies the types of accounts that are reportable, and provides filing relief in the form of exemptions for certain persons with......

  5. Impact of Clean Air Act Regulations on Nitrogen Fate and Transport in Neuse River Basin

    EPA Science Inventory

    This study investigated impacts of Clean Air Act Amendment (CAAA) NOx emissions regulations on the fate and transport of nitrogen for two watersheds in the Neuse River Basin, North Carolina, USA from 1990 to 2020. The Soil and Water Assessment Tool (SWAT) and the Community Multi-...

  6. The National Labor Relations Act and the Regulation of Public Employee Collective Bargaining

    ERIC Educational Resources Information Center

    McCann, Walter; Smiley, Stafford

    1976-01-01

    The arguments for and against federal assumption of the responsibility for regulating the relationship between public employers and public employees are analyzed. It is suggested that the National Labor Relations Act should be extended to include them, thereby imposing upon them a duty to bargain collectively. Available from: the Harvard…

  7. 76 FR 35963 - Disclosure of Information; Privacy Act Regulations; Notice and Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ...) Disclosure to federal financial institutions supervisory agencies and certain other agencies. The Director of... CORPORATION 12 CFR Parts 309 and 310 RIN 3064-AD83 Disclosure of Information; Privacy Act Regulations; Notice... disclosure of information and the PA, as amended. In taking this action the FDIC's goal is to avoid...

  8. 78 FR 32547 - Loan Originator Compensation Requirements Under the Truth in Lending Act (Regulation Z...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... PROTECTION 12 CFR Part 1026 RIN 3170-AA37 Loan Originator Compensation Requirements Under the Truth in... Compensation Requirements under the Truth in Lending Act (Regulation Z) Final Rule, issued on January 20, 2013...\\ One of these final rules was the Loan Originator Compensation Requirements Under the Truth in...

  9. 76 FR 20569 - Horse Protection Act; Petition for Amendments to Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... Society of the United States, the American Society for the Prevention of Cruelty to Animals, the American... Animal and Plant Health Inspection Service 9 CFR Part 11 Horse Protection Act; Petition for Amendments to Regulations AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We...

  10. 77 FR 4498 - Rules and Regulations Under the Wool Products Labeling Act of 1939

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ... meaning set forth in Sec. 303.12 of the Textile Rules. 16 CFR 300.1(k). \\6\\ Federal Trade Commission... ``trimmings'' in Sec. 300.1(k), which incorporates by reference Section 303.12 of the Textile Rules? If so....12 of the Rules and Regulations Under the Textile Fiber Products Identification Act (``Textile...

  11. 75 FR 40754 - Government in the Sunshine Act Regulations of the National Science Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION 45 CFR Part 614 RIN 3145-AA53 Government in the Sunshine Act Regulations of the National Science Board AGENCY: National Science Board (NSB), National Science Foundation (NSF). ACTION: Direct final...

  12. Rationing health protection: a proposal to exempt nuisance dust from US Clean Air Act regulations.

    PubMed

    Centner, Terence J; Colson, Gregory

    2013-03-15

    The US House of Representative has passed a bill called the "Farm Dust Regulation Prevention Act" (Dust Act) that would exempt most types of particulate matter (PM) in rural areas from the air quality controls of the US Clean Air Act. The Dust Act would markedly change the country's air quality standards. An examination of the proposed provisions shows that they would exempt non-combustion PM pollutants from mining, smelting, petroleum production, and power generation from existing air quality standards. Persons downwind from pollutants generated in rural areas could be exposed to concentrations of carcinogenic heavy metals, asbestos, and benzene known to adversely affect their health and ecological resources. Existing federal air quality standards based on science would be replaced by a flexible standard that rations health protection.

  13. Market effects of environmental regulation: coal, railroads, and the 1990 Clean Air Act

    SciTech Connect

    Busse, M.R.; Keohane, N.O.

    2007-01-01

    Many environmental regulations encourage the use of 'clean' inputs. When the suppliers of such an input have market power, environmental regulation will affect not only the quantity of the input used but also its price. We investigate the effect of the Title IV emissions trading program for sulfur dioxide on the market for low-sulfur coal. We find that the two railroads transporting coal were able to price discriminate on the basis of environmental regulation and geographic location. Delivered prices rose for plants in the trading program relative to other plants, and by more at plants near a low-sulfur coal source.

  14. Recovery Act. Development of a Model Energy Conservation Training Program

    SciTech Connect

    none,

    2012-07-05

    The overall objective of this project was to develop an updated model Energy Conservation training program for stationary engineers. This revision to the IUOE National Training Fund’s existing Energy Conservation training curriculum is designed to enable stationary engineers to incorporate essential energy management into routine building operation and maintenance tasks. The curriculum uses a blended learning approach that includes classroom, hands-on, computer simulation and web-based training in addition to a portfolio requirement for a workplace-based learning application. The Energy Conservation training program goal is development of a workforce that can maintain new and existing commercial buildings at optimum energy performance levels. The grant start date was July 6, 2010 and the project continued through September 30, 2012, including a three month non-funded extension.

  15. 43 CFR 1821.13 - What if the specific program regulations conflict with these regulations?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... conflict with these regulations? 1821.13 Section 1821.13 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) APPLICATION PROCEDURES General Information § 1821.13 What if the specific program regulations conflict...

  16. 76 FR 31317 - Privacy Act of 1974, as Amended; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... Privacy Act of 1974, as Amended; Computer Matching Program AGENCY: Department of Education. ACTION: Notice... Management and Budget (OMB) Final Guidance Interpreting the Provisions of Public Law 100-503, the Computer... I, notice is hereby given of the renewal of the computer matching program between the...

  17. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  18. 75 FR 77642 - Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA) Pediatric Quality Measures Program--Notice of Correction...

  19. The Impact of the Workforce Investment Act Training Program on Unemployment in Delaware

    ERIC Educational Resources Information Center

    Tormen, Francis T.

    2013-01-01

    Unemployment is a major social problem in a small East Coast county, with lack of work experience and few marketable skills serving as the contributing factors. The Workforce Investment Act (WIA) training program is a federal program implemented by the states to improve the occupational skills and the employability of the workforce. Scholars have…

  20. The Indian Education Act of 1972. Report of Progress for the Second Year of the Program.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC. Office of Indian Education.

    Program implementation under the American Indian Education Act of 1972 (IEA) is evaluated in this progress report via narrative and tabular data relative to the following: (1) Comparative Overview of 1973 and 1974 Title IV-IEA Programs (project funding, entitlement, and eligibility; grants and funding; Indian pupil enrollment; per pupil…

  1. 30 CFR 843.25 - Energy Policy Act enforcement in States with approved State programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Energy Policy Act enforcement in States with approved State programs. 843.25 Section 843.25 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL ENFORCEMENT § 843.25 Energy Policy...

  2. 30 CFR 843.25 - Energy Policy Act enforcement in States with approved State programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Energy Policy Act enforcement in States with approved State programs. 843.25 Section 843.25 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL ENFORCEMENT § 843.25 Energy Policy...

  3. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  4. 40 CFR 80.610 - What acts are prohibited under the diesel fuel sulfur program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... diesel fuel sulfur program? 80.610 Section 80.610 Protection of Environment ENVIRONMENTAL PROTECTION... What acts are prohibited under the diesel fuel sulfur program? No person shall— (a) Standard, dye... milligrams per liter of solvent yellow 124, except for 500 ppm sulfur diesel fuel produced or imported...

  5. 40 CFR 80.610 - What acts are prohibited under the diesel fuel sulfur program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... diesel fuel sulfur program? 80.610 Section 80.610 Protection of Environment ENVIRONMENTAL PROTECTION... What acts are prohibited under the diesel fuel sulfur program? No person shall— (a) Standard, dye... milligrams per liter of solvent yellow 124, except for 500 ppm sulfur diesel fuel sold, offered for...

  6. 40 CFR 80.610 - What acts are prohibited under the diesel fuel sulfur program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... diesel fuel sulfur program? 80.610 Section 80.610 Protection of Environment ENVIRONMENTAL PROTECTION... What acts are prohibited under the diesel fuel sulfur program? No person shall— (a) Standard, dye... milligrams per liter of solvent yellow 124, except for 500 ppm sulfur diesel fuel sold, offered for...

  7. 40 CFR 80.610 - What acts are prohibited under the diesel fuel sulfur program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... diesel fuel sulfur program? 80.610 Section 80.610 Protection of Environment ENVIRONMENTAL PROTECTION... What acts are prohibited under the diesel fuel sulfur program? No person shall— (a) Standard, dye... milligrams per liter of solvent yellow 124, except for 500 ppm sulfur diesel fuel produced or imported...

  8. An evaluation of the Adults and Children Together (ACT) Against Violence Parents Raising Safe Kids program.

    PubMed

    Portwood, Sharon G; Lambert, Richard G; Abrams, Lyndon P; Nelson, Ellissa Brooks

    2011-08-01

    This study evaluated the effectiveness of the Adults and Children Together (ACT) Against Violence Parents Raising Safe Kids program, developed by the American Psychological Association in collaboration with the National Association for the Education of Young Children, as an economical primary prevention intervention for child maltreatment. Using an experimental design with random assignment to groups, program impact on participating parents' knowledge, behavior, and attitudes compared to those of a comparison group of parents receiving standard community-based support services was examined. As hypothesized, the ACT Parents Raising Safe Kids program achieved positive results in several areas related to effective parenting, including a reduction in the use of harsh verbal and physical discipline and an increase in nurturing behavior. Positive results were observable both at the conclusion of the ACT program and at three-month follow-up. Results further indicated a positive impact on parent expectations and social support for those parents with the greatest need in these areas. Qualitative data collected through focus groups demonstrated that parents themselves perceived numerous benefits to the ACT program, including assistance in controlling their anger, learning and implementing better parenting and discipline strategies, and recognizing when their child's behavior is developmentally appropriate. Overall, findings suggest that the ACT Parents Raising Safe Kids program is a promising primary prevention strategy that can be implemented across diverse community settings.

  9. Emergency Immigration Education Act Programs. Summer ESL Welcome Program for Students of Limited English Proficiency, Summer Bilingual Program, Projects Omega, Wise, and Bell. Summer 1994. OER Report.

    ERIC Educational Resources Information Center

    Roman, Elliott M.

    The Emergency Immigration Education Act supported three distinct programs in New York City in the summer of 1994: (1) the Summer English as a Second Language (ESL) Welcome Program for Students of Limited English Proficiency; (2) the Summer Bilingual Program; and (3) Projects Omega, Wise, and Bell. The projects served 3,443 students in all. The…

  10. Industry invites regulation: the passage of the Pure Food and Drug Act of 1906.

    PubMed Central

    Barkan, I D

    1985-01-01

    Ending its 27-year stranglehold on proposals for federal pure food and drug legislation, Congress passed the Pure Food and Drug Act and its companion bill, the Meat Inspection Act, on June 30, 1906. An unprecedented convergence of consumer, scientific, and industrial support in 1906 prompted such action; most industries even planned for it, hoping regulation would restore the competitiveness of their products on weak foreign and domestic markets. The ways in which these interests converged, and the reasons therefore, suggest a change in their relationships to each other and with the federal government as America headed into the twentieth century. Images p21-a p21-b PMID:3881052

  11. Recovery Act: Training Program Development for Commercial Building Equipment Technicians

    SciTech Connect

    Leah Glameyer

    2012-07-12

    The overall goal of this project has been to develop curricula, certification requirements, and accreditation standards for training on energy efficient practices and technologies for commercial building technicians. These training products will advance industry expertise towards net-zero energy commercial building goals and will result in a substantial reduction in energy use. The ultimate objective is to develop a workforce that can bring existing commercial buildings up to their energy performance potential and ensure that new commercial buildings do not fall below their expected optimal level of performance. Commercial building equipment technicians participating in this training program will learn how to best operate commercial buildings to ensure they reach their expected energy performance level. The training is a combination of classroom, online and on-site lessons. The Texas Engineering Extension Service (TEEX) developed curricula using subject matter and adult learning experts to ensure the training meets certification requirements and accreditation standards for training these technicians. The training targets a specific climate zone to meets the needs, specialized expertise, and perspectives of the commercial building equipment technicians in that zone. The combination of efficient operations and advanced design will improve the internal built environment of a commercial building by increasing comfort and safety, while reducing energy use and environmental impact. Properly trained technicians will ensure equipment operates at design specifications. A second impact is a more highly trained workforce that is better equipped to obtain employment. Organizations that contributed to the development of the training program include TEEX and the Texas Engineering Experiment Station (TEES) (both members of The Texas A&M University System). TEES is also a member of the Building Commissioning Association. This report includes a description of the project

  12. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Are my HCT/P's regulated solely under section 361..., AND CELLULAR AND TISSUE-BASED PRODUCTS General Provisions § 1271.10 Are my HCT/P's regulated solely.../P is regulated solely under section 361 of the PHS Act and the regulations in this part if it...

  13. Prenatal Maternal Stress Programs Infant Stress Regulation

    ERIC Educational Resources Information Center

    Davis, Elysia Poggi; Glynn, Laura M.; Waffarn, Feizal; Sandman, Curt A.

    2011-01-01

    Objective: Prenatal exposure to inappropriate levels of glucocorticoids (GCs) and maternal stress are putative mechanisms for the fetal programming of later health outcomes. The current investigation examined the influence of prenatal maternal cortisol and maternal psychosocial stress on infant physiological and behavioral responses to stress.…

  14. 34 CFR 400.5 - Under what conditions may funds under the Act be used for the joint funding of programs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Under what conditions may funds under the Act be used for the joint funding of programs? 400.5 Section 400.5 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF...

  15. 34 CFR 400.5 - Under what conditions may funds under the Act be used for the joint funding of programs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Under what conditions may funds under the Act be used for the joint funding of programs? 400.5 Section 400.5 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF...

  16. 76 FR 14275 - Regulations Issued Under the Export Grape and Plum Act; Revision to the Minimum Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... Service 7 CFR Part 35 Regulations Issued Under the Export Grape and Plum Act; Revision to the Minimum... requirements under the Export Grape and Plum Act. This rule changes the minimum bunch weight requirement for... under authority of the Export Grape and Plum Act, as amended (7 U.S.C. 591-599), hereinafter referred...

  17. 77 FR 33635 - Amendment to the Bank Secrecy Act Regulations-Requirement That Clerks of Court Report Certain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ... Financial Crimes Enforcement Network 31 CFR Part 1010 RIN 1506-AB17 Amendment to the Bank Secrecy Act Regulations--Requirement That Clerks of Court Report Certain Currency Transactions AGENCY: Financial Crimes... Financial Transactions Reporting Act of 1970, as amended by the USA PATRIOT Act of 2001 and...

  18. 17 CFR 270.14a-1 - Use of notification pursuant to regulation E under the Securities Act of 1933.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of 1933 by a small business investment company operating under the Small Business Investment Act of... to regulation E under the Securities Act of 1933. 270.14a-1 Section 270.14a-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT...

  19. 78 FR 45842 - Amendments to the 2013 Mortgage Rules Under the Real Estate Settlement Procedure Act (Regulation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... From the Federal Register Online via the Government Publishing Office BUREAU OF CONSUMER FINANCIAL PROTECTION 12 CFR Parts 1024 and 1026 RIN 3170-AA37 Amendments to the 2013 Mortgage Rules Under the Real Estate Settlement Procedure Act (Regulation X) and the Truth in Lending Act (Regulation Z) Correction...

  20. 26 CFR 1.706-2T - Temporary regulations; question and answer under the Tax Reform Act of 1984.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Temporary regulations; question and answer under the Tax Reform Act of 1984. 1.706-2T Section 1.706-2T Internal Revenue INTERNAL REVENUE SERVICE...-2T Temporary regulations; question and answer under the Tax Reform Act of 1984. Question 1:...

  1. Allosteric ACTion: the varied ACT domains regulating enzymes of amino-acid metabolism.

    PubMed

    Lang, Eric J M; Cross, Penelope J; Mittelstädt, Gerd; Jameson, Geoffrey B; Parker, Emily J

    2014-12-01

    Allosteric regulation of enzyme activity plays important metabolic roles. Here we review the allostery of enzymes of amino-acid metabolism conferred by a discrete domain known as the ACT domain. This domain of 60-70 residues has a βαββαβ topology leading to a four-stranded β4β1β3β2 antiparallel sheet with two antiparallel helices on one face. Extensive sequence variation requires a combined sequence/structure/function analysis for identification of the ACT domain. Common features include highly varied modes of self-association of ACT domains, ligand binding at domain interfaces, and transmittal of allosteric signals through conformational changes and/or the manipulation of quaternary equilibria. A recent example illustrates the relatively facile adoption of this versatile module of allostery by gene fusion.

  2. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  3. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  4. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  5. 76 FR 39119 - Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of Housing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... URBAN DEVELOPMENT Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of... ED. SUMMARY: In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer... Program In accordance with the Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503),...

  6. 78 FR 70971 - Privacy Act of 1974, as Amended; Notice of Computer Matching Program (Railroad Retirement Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Privacy Act of 1974, as Amended; Notice of Computer Matching Program (Railroad Retirement Board--Office of... computer-matching program that expired on February 1, 2013. ] SUMMARY: As required by the Privacy Act of... the use of computer matching by Federal agencies when records contained in a Privacy Act System...

  7. 75 FR 53004 - Privacy Act of 1974, as Amended; Notice of Computer-Matching Program (Railroad Retirement Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Privacy Act of 1974, as Amended; Notice of Computer-Matching Program (Railroad Retirement Board--Office of... computer-matching program that expired on August 13, 2010. SUMMARY: As required by the Privacy Act of 1974... the use of computer-matching by Federal agencies when records contained in a Privacy Act System...

  8. 45 CFR 90.3 - What programs or activities does the Age Discrimination Act of 1975 cover?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Discrimination Act of 1975 cover? 90.3 Section 90.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... FINANCIAL ASSISTANCE General § 90.3 What programs or activities does the Age Discrimination Act of 1975 cover? (a) The Age Discrimination Act of 1975 applies to any program or activity receiving...

  9. New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination

    PubMed Central

    Wahls, Wayne P.; Davidson, Mari K.

    2012-01-01

    How do cells position the Spo11 (Rec12)-dependent initiation of meiotic recombination at hotspots? The mechanisms are poorly understood and a prevailing view is that they differ substantially between phylogenetic groups. However, recent work discovered that individual species have multiple different DNA sequence-specific, protein–DNA complexes that regulate (and are essential for the activation of) recombination hotspots. The cis-acting elements function combinatorially with documented examples of synergism, antagonism and redundancy. Furthermore, we provide evidence that all currently well-defined modules of this multifactorial, cis-acting regulation are conserved functionally between taxa whose latest common ancestor occurred more than 1 billion years ago. Functionally conserved components include the ATF/CREB-family heterodimer Atf1-Pcr1 and its CRE-like DNA site M26, the CCAAT-box-binding complex Php2-Php3-Php5 and the CCAAT-box, and the zinc-finger protein Rst2 and its Oligo-C motif. The newfound multiplicity, functional redundancy and conservation of cis-acting controls constitute a paradigm shift with broad implications. They provide compelling evidence that most meiotic recombination is, like transcription, regulated by sequence-specific protein–DNA complexes. And the new findings provide important mechanistic insight, such as a solution to the conundrum that Prdm9 is a ‘master regulator’ of—yet is dispensable for—hotspot activity in mammals. PMID:22904082

  10. Programmed Cell Death of Dendritic Cells in Immune Regulation

    PubMed Central

    Chen, Min; Wang, Jin

    2010-01-01

    Summary Programmed cell death is essential for the maintenance of lymphocyte homeostasis and immune tolerance. Dendritic cells (DCs), the most efficient antigen presenting cells, represent a small cell population in the immune system. However, DCs play major roles in the regulation of both innate and adaptive immune responses. Programmed cell death in DCs is essential for regulating DC homeostasis and consequently, the scope of immune responses. Interestingly, different DC subsets show varied turnover rates in vivo. The conventional DCs are relatively short-lived in most lymphoid organs, while plasmacytoid DCs are long-lived cells. Mitochondrion-dependent programmed cell death plays an important role in regulating spontaneous DC turnover. Antigen-specific T cells are also capable of killing DCs, thereby providing a mechanism for negative feedback regulation of immune responses. It has been shown that a surplus of DCs due to defects in programmed cell death leads to overactivation of lymphocytes and the onset of autoimmunity. Studying programmed cell death in DCs will shed light on the roles for DC turnover in the regulation of the duration and magnitude of immune responses in vivo, and in the maintenance of immune tolerance. PMID:20636805

  11. Federal privacy regulations and the provision of Early Hearing Detection and Intervention programs.

    PubMed

    Houston, K Todd; Behl, Diane D; White, Karl R; Forsman, Irene

    2010-08-01

    To be successful, Early Hearing Detection and Intervention (EHDI) programs require individually identifiable information about children to be shared among people who are responsible for screening, diagnosis, early intervention, family support, and medical home services. Pediatricians and other stakeholders in the EHDI process often point to federal laws that were passed to ensure privacy and confidentiality in health care and educational programs as major obstacles to achieving efficient and effective EHDI programs. In this article we summarize the provisions of 3 federal laws (the Health Insurance Portability and Accountability Act [HIPAA], the Family Education Rights and Privacy Act [FERPA], and Part C privacy regulations of the Individuals With Disabilities Education Act [IDEA]) that most directly affect information-sharing in EHDI programs. We suggest strategies for sharing the information needed to operate successful EHDI programs while remaining in compliance with these laws, including obtaining signed parental consent to share information between providers, including an option on the individual family services plan for parents to permit sharing of the plan with pediatricians and other providers, and giving copies of all relevant test results to parents to share with providers as they wish.

  12. Cooperation in USDA studies and evaluations, and full use of federal funds in nutrition assistance programs nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010, Public Law 111-296. Final Rule.

    PubMed

    2011-06-29

    This final rule incorporates into the regulations governing the Programs authorized under the Richard B. Russell National School Lunch Act (NSLA) and the Child Nutrition Act of 1966 (CNA) two nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010 (HHFK Act). The HHFK Act requires State and local cooperation in Department of Agriculture studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also amends the NSLA to stipulate that Federal funds must not be subject to State budget restrictions or limitations, including hiring freezes, work furloughs, and travel restrictions. This final rule amends regulations for the National School Lunch Program; the Special Milk Program for Children; the School Breakfast Program; the Summer Food Service Program; the Child and Adult Care Food Program; State Administrative Expense Funds ; the Special Supplemental Nutrition Program for Women, Infants and Children; and the WIC Farmers' Market Nutrition Program. These provisions will strengthen program integrity by ensuring that sufficient data is made available for studies and evaluations. Additionally, exempting Federal funds from State budgetary restrictions or limitations is intended to increase the ability of State agencies to administer USDA's nutrition assistance programs effectively.

  13. 75 FR 81831 - Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ...] [Page 81831] [FR Doc No: 2010-32686] DEPARTMENT OF AGRICULTURE Food and Nutrition Service 7 CFR Part 274 RIN 0584-AD48 Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update and Reorganization To Reflect the End of Coupon Issuance Systems AGENCY: Food and...

  14. 75 FR 18377 - Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... / Monday, April 12, 2010 / Rules and Regulations#0;#0; ] DEPARTMENT OF AGRICULTURE Food and Nutrition Service 7 CFR part 274 RIN 0584-AD48 Supplemental Nutrition Assistance Program, Regulation Restructuring... and Nutrition Service, USDA. ACTION: Direct final rule. SUMMARY: This direct final rule updates...

  15. 78 FR 29748 - Privacy Act of 1974; Computer Matching Program Between the Department of Education and the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... Privacy Act of 1974; Computer Matching Program Between the Department of Education and the Department of... program. In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer Matching... continuation of a computer matching program between the Department of Education and the Department of...

  16. ACT against Violence Parents Raising Safe Kids Program: Effects on Maltreatment-Related Parenting Behaviors and Beliefs

    ERIC Educational Resources Information Center

    Knox, Michele S.; Burkhart, Kimberly; Hunter, Kimberly E.

    2011-01-01

    The ACT Against Violence Parents Raising Safe Kids program (ACT-PRSK) is an interactive violence prevention program developed by the American Psychological Association for parents of young children. The program teaches and supports parents in the areas of child development, roots and consequences of violence, anger management for adults and…

  17. 75 FR 37456 - Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... URBAN DEVELOPMENT Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of... to administer the Green Retrofit Program (GRP) authorized by the Recovery Act. The legislation... Lists the Following Information Title of Proposal: Green Retrofit Program of Title XII of the...

  18. Industry's voluntary program: Community Awareness and Emergency Response Program and the Emergency Planning and Community Right-to-Know Act

    SciTech Connect

    Cooper, J.S. )

    1990-10-01

    This paper describes the chemical industry's Community Awareness and Emergency Response (CAER) Program, and voluntary and mandatory actions by the chemical industry to comply with the major environmental legislation. The chemical industry started the voluntary CAER Program soon after the Bhopal Disaster in 1984; it is coordinated through the Chemical Manufacturer's Association. This program, which began in March 1985, is a long-term industry commitment to develop a community outreach program and to improve local emergency response planning. The Congress of the United States began, in 1985, to consider proposals for mandatory programs. This led to enactment of the Superfund Amendments and Reauthorization Act of 1986, known as SARA. A portion of this Act, entitled Title III is also known as the Emergency Planning and Community Right-to-Know Act. Although this legislation has many mandatory requirements, it should be emphasized that a significant degree of voluntary industrial participation is needed if the purposes of the statute are to be achieved. Title III has created an intricate and still evolving system that ties together the EPA, industrial plant managers, state emergency response commissions, local emergency planning committees and fire departments with jurisdiction over the facility. Each of these groups has a different role and responsibilities but must work cooperatively with other participants. Because of the intricate network of participants, the magnitude of the information flow, and the continuing evolution of the system, unique public relations problems exist in order to comply with Title III.

  19. 75 FR 66245 - HUD Programs: Violence Against Women Act Conforming Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ...This final rule follows a November 28, 2008, interim rule that conformed HUD's regulations to those provisions of the Violence Against Women Act (VAWA), as enacted in January 2006, and subsequently amended in August 2006, that were determined to be self-implementing. VAWA provides statutory protections for victims of domestic violence, dating violence, sexual assault, and stalking. Such......

  20. Redox regulation in metabolic programming and inflammation.

    PubMed

    Griffiths, Helen R; Gao, Dan; Pararasa, Chathyan

    2017-02-12

    Energy metabolism and redox state are intrinsically linked. In order to mount an adequate immune response, cells must have an adequate and rapidly available energy resource to migrate to the inflammatory site, to generate reactive oxygen species using NADPH as a cofactor and to engulf bacteria or damaged tissue. The first responder cells of the innate immune response, neutrophils, are largely dependent on glycolysis. Neutrophils are relatively short-lived, dying via apoptosis in the process of bacterial killing through production of hypochlorous acid and release of extracellular NETs. Later on, the most prevalent recruited innate immune cells are monocytes. Their role is to complete a damage limitation exercise initiated by neutrophils and then, as re-programmed M2 macrophages, to resolve the inflammatory event. Almost twenty five years ago, it was noted that macrophages lose their glycolytic capacity and become anti-inflammatory after treatment with corticosteroids. In support of this we now understand that, in contrast to early responders, M2 macrophages are predominantly dependent on oxidative phosphorylation for energy. During early inflammation, polarisation towards M1 macrophages is dependent on NOX2 activation which, via protein tyrosine phosphatase oxidation and AKT activation, increases trafficking of glucose transporters to the membrane and consequently increases glucose uptake for glycolysis. In parallel, mitochondrial efficiency is likely to be compromised via nitrosylation of the electron transport chain. Resolution of inflammation is triggered by encounter with apoptotic membranes exposing oxidised phosphatidylserine that interact with the scavenger receptor, CD36. Downstream of CD36, activation of AMPK and PPARγ elicits mitochondrial biogenesis, arginase expression and a switch towards oxidative phosphorylation in the M2 macrophage. Proinflammatory cytokine production by M2 cells decreases, but anti-inflammatory and wound healing growth factor

  1. Interactions between Energy Efficiency Programs funded under the Recovery Act and Utility Customer-Funded Energy Efficiency Programs

    SciTech Connect

    Goldman, Charles A.; Stuart, Elizabeth; Hoffman, Ian; Fuller, Merrian C.; Billingsley, Megan A.

    2011-02-25

    Since the spring of 2009, billions of federal dollars have been allocated to state and local governments as grants for energy efficiency and renewable energy projects and programs. The scale of this American Reinvestment and Recovery Act (ARRA) funding, focused on 'shovel-ready' projects to create and retain jobs, is unprecedented. Thousands of newly funded players - cities, counties, states, and tribes - and thousands of programs and projects are entering the existing landscape of energy efficiency programs for the first time or expanding their reach. The nation's experience base with energy efficiency is growing enormously, fed by federal dollars and driven by broader objectives than saving energy alone. State and local officials made countless choices in developing portfolios of ARRA-funded energy efficiency programs and deciding how their programs would relate to existing efficiency programs funded by utility customers. Those choices are worth examining as bellwethers of a future world where there may be multiple program administrators and funding sources in many states. What are the opportunities and challenges of this new environment? What short- and long-term impacts will this large, infusion of funds have on utility customer-funded programs; for example, on infrastructure for delivering energy efficiency services or on customer willingness to invest in energy efficiency? To what extent has the attribution of energy savings been a critical issue, especially where administrators of utility customer-funded energy efficiency programs have performance or shareholder incentives? Do the new ARRA-funded energy efficiency programs provide insights on roles or activities that are particularly well-suited to state and local program administrators vs. administrators or implementers of utility customer-funded programs? The answers could have important implications for the future of U.S. energy efficiency. This report focuses on a selected set of ARRA-funded energy

  2. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M. ); Hemenway, A. )

    1991-01-01

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  3. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M.; Hemenway, A.

    1991-12-31

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  4. 78 FR 13298 - Notice of Retrospective Review of the Americans With Disabilities Act Regulations for Over-the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... Act Regulations for Over-the-Road Bus Operators; Request for Comments AGENCY: Office of the Secretary...) implementing regulations for over-the-road bus (OTRB) operators. The DOT will review regulations specified in... Stat. 327, 42 U.S.C. 225 and 611), which required the accessibility of new over-the-road buses...

  5. 78 FR 44685 - Amendments to the 2013 Mortgage Rules Under the Real Estate Settlement Procedures Act (Regulation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... Final Rule), 78 FR 6407 (Jan. 30, 2013). \\2\\ Mortgage Servicing Rules Under the Real Estate Settlement... Final Rules), 78 FR 10695 (Feb. 14, 2013) (Regulation X), 78 FR 10901 (Feb. 14, 2013) (Regulation Z). \\3\\ Amendments to the 2013 Escrows Final Rule under the Truth in Lending Act (Regulation Z), 78 FR 30739 (May...

  6. ACTS propagation experiment discussion: Ka-band propagation measurements using the ACTS propagation terminal and the CSU-CHILL and Space Communications Technology Center Florida propagation program

    NASA Technical Reports Server (NTRS)

    Bringi, V. N.; Chandrasekar, V.; Mueller, Eugene A.; Turk, Joseph; Beaver, John; Helmken, Henry F.; Henning, Rudy

    1993-01-01

    Papers on Ka-band propagation measurements using the ACTS propagation terminal and the Colorado State University CHILL multiparameter radar and on Space Communications Technology Center Florida Propagation Program are discussed. Topics covered include: microwave radiative transfer and propagation models; NASA propagation terminal status; ACTS channel characteristics; FAU receive only terminal; FAU terminal status; and propagation testbed.

  7. 76 FR 42769 - Privacy Act of 1974; Report of Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... income. VA will also match records of veterans receiving disability compensation at the 100 percent rate... use this information to adjust VA benefit payments as prescribed by law. The proposed matching program... provided in accordance with the provisions of the Privacy Act of 1974 as amended by Public Law...

  8. 76 FR 41246 - Pesticide Program Dialogue Committee, Pesticide Registration Improvement Act Process Improvement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... Registration Improvement Act (PRIA) Process Improvement Work Group. EPA plans to meet its ESA consultation... the PRIA Process Improvement Work Group continues the dialogue between EPA and interested stake...: The Pesticide Program Dialogue Committee (PPDC) provides a forum for a diverse group of stake...

  9. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Program Fraud Civil Remedies Act (PFCRA). 516.68 Section 516.68 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68...

  10. Job Training Partnership Act PY '91 Title II-A Program Review.

    ERIC Educational Resources Information Center

    McDaniel, Sue; Riley, Dee Ann

    Management information system (MIS) data about women's participation in Missouri's job training system funded under Title II-A of the Job Training Partnership Act (JTPA) in program year 1992 were analyzed. Analysis of data from Missouri's 15 service delivery areas (SDAs) established the following: 75% of the state's 4,598 female JTPA participants…

  11. Local Evaluation of Programs Funded under the Drug-Free Schools and Communities Act. Final Report.

    ERIC Educational Resources Information Center

    Tashjian, Michael D.; Elliott, Barbara

    In September 1993 the U.S. Department of Education (ED) released a handbook to assist school- and community-based practitioners in designing and conducting evaluations of drug- and violence-prevention programs funded under the Drug Free Schools and Communities Act (DFSCA). A study was undertaken to assess the level of customer satisfaction with…

  12. 77 FR 62469 - Defense Logistics Agency Freedom of Information Act Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... of the Secretary 32 CFR Part 300 Defense Logistics Agency 32 CFR Part 1285 RIN 0790-AI87 Defense Logistics Agency Freedom of Information Act Program AGENCY: Defense Logistics Agency, DoD. ACTION: Proposed rule. SUMMARY: The Defense Logistics Agency (DLA) proposes to revise and update its existing...

  13. Households Eligible for a National Farmworker Program Under the Comprehensive Employment and Training Act of 1973.

    ERIC Educational Resources Information Center

    Rowe, Gene; Smith, Leslie Whitener

    The report contains data pertaining to the number and distribution of U.S. farm wageworkers and their dependents who were eligible in 1973 for the national farmworker program under the 1973 Comprehensive Employment and Training Act's (CETA) Title III, Section 303 (a). Information is given by migratory status, ethnic group, earning, and region.…

  14. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT... of 1986. In the case of penalties assessed under part 355 of this chapter, an additional penalty...

  15. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT... of 1986. In the case of penalties assessed under part 355 of this chapter, an additional penalty...

  16. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT... of 1986. In the case of penalties assessed under part 355 of this chapter, an additional penalty...

  17. The Drug-Free Schools and Communities Act of 1986: Policy, Formation, Causation, and Program Implementation.

    ERIC Educational Resources Information Center

    Lark, Melody

    The Drug-Free Schools and Communities Act of 1986, the National Drug Control Strategy (1989-92), the Five-Year State Master Plan to Reduce Drug and Alcohol Abuse in California (1988-92), and the perspectives of education administrators (n=14) of drug prevention programs in select California public secondary schools (1994-95) were analyzed. The…

  18. Individuals with Disabilities Education Act's Early Childhood Programs: Powerful Vision and Pesky Details

    ERIC Educational Resources Information Center

    Hebbeler, Kathleen; Spiker, Donna; Kahn, Lynne

    2012-01-01

    National policy affects local practice in a variety of ways and through a variety of mechanisms. In this article, the authors examine what has been learned from Individuals With Disabilities Education Act's (IDEA) two early childhood (EC) programs about the power and limitations of policy as a lever to improve the lives of young children.…

  19. Job Training Partnership Act Handbook for DPI/JTPA 8% Programs. 1988-89.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Support Programs.

    This handbook has been developed to assist Job Training Partnership Act (JTPA) coordinators with the information and procedures required for successful implementation of the JTPA in North Carolina public schools. The following are covered: program objectives, job requirements, file checklists, outreach/recruitment, marketing activities, program…

  20. 76 FR 55125 - Finance, Budget & Program Committee Meeting of the Board of Directors; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Meeting of the Board of Directors; Sunshine Act TIME AND DATE: 2 p.m., Wednesday, September 7, 2011 PLACE: 1325 G Street, NW., Suite 800, Boardroom, Washington,...

  1. 78 FR 24438 - Board of Directors Finance, Budget & Program Committee: Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Board of Directors Finance, Budget & Program Committee: Sunshine Act Meeting TIME AND DATE: 1:00 p.m., Thursday, May 2, 2013. PLACE: 1325 G Street NW., Suite 800, Boardroom, Washington, DC...

  2. 77 FR 56238 - Finance, Budget & Program. Committee Meeting of the Board of Directors; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program. Committee Meeting of the Board of Directors; Sunshine Act TIME & DATE: 3 p.m., Thursday, September 20, 2012. PLACE: 1325 G Street NW., Suite 800, Boardroom, Washington,...

  3. 76 FR 67764 - Finance, Budget & Program Committee Board of Directors Meeting; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Board of Directors Meeting; Sunshine Act Time & Date: 10 a.m., Thursday, November 3, 2011. Place: 1325 G Street, NW., Suite 800, Boardroom, Washington, DC 20005....

  4. 78 FR 65716 - Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors TIME & DATE: 2:00 p.m., Thursday, November 7, 2013. PLACE: Telephonic Meeting. STATUS: Open. CONTACT...

  5. Rapid Feedback Evaluation of the Career Education Incentive Act Program. Phase II Technical Report.

    ERIC Educational Resources Information Center

    American Institutes for Research in the Behavioral Sciences, Palo Alto, CA.

    A rapid feedback evaluation of the federal career education incentive program was conducted to compile readily available information regarding the implementation of career education under the Career Education Incentive Act (PL 95-207). Attention was directed toward the activities and accomplishments of the four major actors in the career education…

  6. Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration

    PubMed Central

    Bernis, Cyril; Swift-Taylor, Beth; Nord, Matthew; Carmona, Sarah; Chook, Yuh Min; Forbes, Douglass J.

    2014-01-01

    The nuclear import receptors importin β and transportin play a different role in mitosis: both act phenotypically as spatial regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclusively around chromatin. Importin β is known to act by repressing assembly factors in regions distant from chromatin, whereas RanGTP produced on chromatin frees factors from importin β for localized assembly. The mechanism of transportin regulation was unknown. Diametrically opposed models for transportin action are as follows: 1) indirect action by RanGTP sequestration, thus down-regulating release of assembly factors from importin β, and 2) direct action by transportin binding and inhibiting assembly factors. Experiments in Xenopus assembly extracts with M9M, a superaffinity nuclear localization sequence that displaces cargoes bound by transportin, or TLB, a mutant transportin that can bind cargo and RanGTP simultaneously, support direct inhibition. Consistently, simple addition of M9M to mitotic cytosol induces microtubule aster assembly. ELYS and the nucleoporin 107–160 complex, components of mitotic kinetochores and nuclear pores, are blocked from binding to kinetochores in vitro by transportin, a block reversible by M9M. In vivo, 30% of M9M-transfected cells have spindle/cytokinesis defects. We conclude that the cell contains importin β and transportin “global positioning system”or “GPS” pathways that are mechanistically parallel. PMID:24478460

  7. Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration.

    PubMed

    Bernis, Cyril; Swift-Taylor, Beth; Nord, Matthew; Carmona, Sarah; Chook, Yuh Min; Forbes, Douglass J

    2014-04-01

    The nuclear import receptors importin β and transportin play a different role in mitosis: both act phenotypically as spatial regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclusively around chromatin. Importin β is known to act by repressing assembly factors in regions distant from chromatin, whereas RanGTP produced on chromatin frees factors from importin β for localized assembly. The mechanism of transportin regulation was unknown. Diametrically opposed models for transportin action are as follows: 1) indirect action by RanGTP sequestration, thus down-regulating release of assembly factors from importin β, and 2) direct action by transportin binding and inhibiting assembly factors. Experiments in Xenopus assembly extracts with M9M, a superaffinity nuclear localization sequence that displaces cargoes bound by transportin, or TLB, a mutant transportin that can bind cargo and RanGTP simultaneously, support direct inhibition. Consistently, simple addition of M9M to mitotic cytosol induces microtubule aster assembly. ELYS and the nucleoporin 107-160 complex, components of mitotic kinetochores and nuclear pores, are blocked from binding to kinetochores in vitro by transportin, a block reversible by M9M. In vivo, 30% of M9M-transfected cells have spindle/cytokinesis defects. We conclude that the cell contains importin β and transportin "global positioning system"or "GPS" pathways that are mechanistically parallel.

  8. ATH1 and KNAT2 proteins act together in regulation of plant inflorescence architecture.

    PubMed

    Li, Yang; Pi, Limin; Huang, Hai; Xu, Lin

    2012-02-01

    The inflorescence of flowering plants is a highly organized structure, not only contributing to plant reproductive processes, but also constituting an important part of the entire plant morphology. Previous studies have revealed that the class-I KNOTTED1-like homeobox (KNOX) genes BREVIPEDICELLUS (BP or KNAT1), KNAT2, and KNAT6 play essential roles in inflorescence architecture. Pedicel morphology is known to contribute greatly to inflorescence architecture, and BP negatively regulates KNAT2 and KNAT6 to ensure that pedicels have a normal upward-pointing orientation. These findings indicate that a genetic network exists in controlling pedicel orientation, but how this network functions in the developmental process remains elusive. Here it is reported that the ARABIDOPSIS THALIANA HOMEOBOX GENE1 (ATH1) gene, which belongs to the BELL1-like homeodomain gene family, is a new member participating in regulating pedicel orientation in the class-I KNOX network. In a genetic screening for suppressors of isoginchaku-2D, a gain-of-function ASYMMETRIC LEAVES2 mutant that displays downward-pointing pedicels, a suppressor mutant was obtained. Characterization of this mutant revealed that the mutation corresponds to ATH1. Genetic analysis indicated that ATH1 acts mainly in the KNAT2 pathway. Yeast two-hybrid and bimolecular fluorescence complementation assays demonstrated that ATH1 physically interacts with KNAT2. The data indicate that the ATH1-KNAT2 complex acts redundantly with KNAT6, both of which are negatively regulated by BP during pedicel development.

  9. The omniscient placenta: Metabolic and epigenetic regulation of fetal programming.

    PubMed

    Nugent, Bridget M; Bale, Tracy L

    2015-10-01

    Fetal development could be considered a sensitive period wherein exogenous insults and changes to the maternal milieu can have long-term impacts on developmental programming. The placenta provides the fetus with protection and necessary nutrients for growth, and responds to maternal cues and changes in nutrient signaling through multiple epigenetic mechanisms. The X-linked enzyme O-linked-N-acetylglucosamine transferase (OGT) acts as a nutrient sensor that modifies numerous proteins to alter various cellular signals, including major epigenetic processes. This review describes epigenetic alterations in the placenta in response to insults during pregnancy, the potential links of OGT as a nutrient sensor to placental epigenetics, and the implications of placental epigenetics in long-term neurodevelopmental programming. We describe the role of placental OGT in the sex-specific programming of hypothalamic-pituitary-adrenal (HPA) axis programming deficits by early prenatal stress as an example of how placental signaling can have long-term effects on neurodevelopment.

  10. The omniscient placenta: Metabolic and epigenetic regulation of fetal programming

    PubMed Central

    Nugent, Bridget M.; Bale, Tracy L.

    2015-01-01

    Fetal development could be considered a sensitive period wherein exogenous insults and changes to the maternal milieu can have long-term impacts on developmental programming. The placenta provides the fetus with protection and necessary nutrients for growth, and responds to maternal cues and changes in nutrient signaling through multiple epigenetic mechanisms. The X-linked enzyme O-linked-N-acetylglucosamine transferase (OGT) acts as a nutrient sensor that modifies numerous proteins to alter various cellular signals, including major epigenetic processes. This review describes epigenetic alterations in the placenta in response to insults during pregnancy, the potential links of OGT as a nutrient sensor to placental epigenetics, and the implications of placental epigenetics in long-term neurodevelopmental programming. We describe the role of placental OGT in the sex-specific programming of hypothalamic-pituitary-adrenal (HPA) axis programming deficits by early prenatal stress as an example of how placental signaling can have long-term effects on neurodevelopment. PMID:26368654

  11. Clean Water Act's Section 404 permit program enters its adolescence: an institutional and programmatic perspective

    SciTech Connect

    Blumm, M.C.

    1980-01-01

    Section 404 of the Clean Water Act deals with permit requirements and has become a major Federal regulatory program. The program's scope and procedures are reviewed, with emphasis given to the responsibilities of the agencies involved and the opportunities for discharging these duties with the maximum efficiency. Interagency and intergovernmental cooperation are crucial to the effectiveness of the broad ranging 404 program. The Environmental Protection Agency's role is seen as one of oversight and guidance, as well as issuing criteria and monitoring enforcement. The appropriate roles for other Federal and state agencies, state governments, Congress, and the public are outlined and also depend on cooperation for effective implementation. 333 references. (DCK)

  12. Identification of trans-acting factors regulating SamDC expression in Oryza sativa

    SciTech Connect

    Basu, Supratim; Roychoudhury, Aryadeep; Sengupta, Dibyendu N.

    2014-03-07

    Highlights: • Identification of cis elements responsible for SamDC expression by in silico analysis. • qPCR analysis of SamDC expression to abiotic and biotic stress treatments. • Detection of SamDC regulators using identified cis-elements as probe by EMSA. • Southwestern Blot analysis to predict the size of the trans-acting factors. - Abstract: Abiotic stress affects the growth and productivity of crop plants; to cope with the adverse environmental conditions, plants have developed efficient defense machinery comprising of antioxidants like phenolics and flavonoids, and osmolytes like polyamines. SamDC is a key enzyme in the polyamine biosynthesis pathway in plants. In our present communication we have done in silico analysis of the promoter region of SamDC to look for the presence of different cis-regulatory elements contributing to its expression. Based on the presence of different cis-regulatory elements we completed comparative analysis of SamDC gene expression in rice lamina of IR-29 and Nonabokra by qPCR in response to the abiotic stress treatments of salinity, drought, cold and the biotic stress treatments of ABA and light. Additionally, to explore the role of the cis-regulatory elements in regulating the expression of SamDC gene in plants we comparatively analyzed the binding of rice nuclear proteins prepared from IR-29 and Nonabokra undergoing various stress treatments. The intensity of the complex formed was low and inducible in IR-29 in contrast to Nonabokra. Southwestern blot analysis helped in predicting the size of the trans-acting factors binding to these cis-elements. To our knowledge this is the first report on the comprehensive analysis of SamDC gene expression in rice and identification of the trans-acting factors regulating its expression.

  13. 25 CFR 518.2 - Who will administer the self-regulation program for the Commission?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false Who will administer the self-regulation program for the... PROVISIONS SELF-REGULATION OF CLASS II GAMING § 518.2 Who will administer the self-regulation program for the Commission? The self-regulation program will be administered by the Office of Self-Regulation. The...

  14. ACT: a program for calculation of the changes in radiological source terms with time

    SciTech Connect

    Woolfolk, S.W.

    1985-08-12

    The program ACT calculates the source term activity from a set of initial activities as a function of discrete time steps. This calculation considers inbreeding of daughter products. ACT also calculates ''Probable Release'', which is the activity at a given time multiplied by both the fraction released and the probability of the release. The ''Probable Release'' not only assumes that the fraction released is a single step function with time, but that the probability of release is zero for a limited period and it can be described by the ''Wisconsin Regression'' function using time as the independent variable. Finally, the program calculates the time integrated sum of the ''Probable Release'' for each isotope. This program is intended to support analysis of releases from radioactive waste disposal sites such as those required by 40 CFR 191.

  15. 76 FR 14566 - Federal Acquisition Regulation; Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... 9000-AL88 Federal Acquisition Regulation; Socioeconomic Program Parity AGENCY: Department of Defense...), which became effective on February 4, 2011. SBA's rule provides parity for WOSBs with SBA's other small.... Section 1347 clarified that there is parity, rather than an order of precedence, and the purpose of...

  16. 76 FR 26220 - Federal Acquisition Regulation; Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 48 CFR Part 19 RIN 9000-AL88 Federal Acquisition Regulation; Socioeconomic Program Parity AGENCY: Department of Defense (DoD),...

  17. A care improvement program acting as a powerful learning environment to support nursing students learning facilitation competencies.

    PubMed

    Jukema, Jan S; Harps-Timmerman, Annelies; Stoopendaal, Annemiek; Smits, Carolien H M

    2015-11-01

    Change management is an important area of training in undergraduate nursing education. Successful change management in healthcare aimed at improving practices requires facilitation skills that support teams in attaining the desired change. Developing facilitation skills in nursing students requires formal educational support. A Dutch Regional Care Improvement Program based on a nationwide format of change management in healthcare was designed to act as a Powerful Learning Environment for nursing students developing competencies in facilitating change. This article has two aims: to provide comprehensive insight into the program components and to describe students' learning experiences in developing their facilitation skills. This Dutch Regional Care Improvement Program considers three aspects of a Powerful Learning Environment: self-regulated learning; problem-based learning; and complex, realistic and challenging learning tasks. These three aspects were operationalised in five distinct areas of facilitation: increasing awareness of the need for change; leadership and project management; relationship building and communication; importance of the local context; and ongoing monitoring and evaluation. Over a period of 18 months, 42 nursing students, supported by trained lecturer-coaches, took part in nine improvement teams in our Regional Care Improvement Program, executing activities in all five areas of facilitation. Based on the students' experiences, we propose refinements to various components of this program, aimed at strengthenin the learning environment. There is a need for further detailed empirical research to study the impact this kind of learning environment has on students developing facilitation competencies in healthcare improvement.

  18. The European "clinical trial" regulation; relationship with the Jardé Act: a Giens workshop.

    PubMed

    Lemaire, François; Marchenay, Brigitte; Chassany, Olivier; Barthélémy, Philippe; Bouzzagou, Mohamed; Comet, Denis; Delval, Cécile; Dubray, Claude; Fouret, Cécile; Frija-Orvoen, Elisabeth; Gambotti, Laetitia; Lamarque, Véronique; d'Orsay, Geneviève; Plattner, Valérie; Sibenaler, Claire; Roux, Jacques; Thoby, Frédérique

    2015-01-01

    In May 2014, the European Union Parliament and Council published a new regulation on clinical trials on medicinal products for human use, which is designed to replace Directive 2001/20/EC. It will not come into effect until 2016. Nevertheless, it is essential to examine its relationship with national legislation, i.e. the Jardé Act, whose implementation has been delayed pending publication of the European regulation. The Giens workshop identified and examined the various issues that this relationship is bound to raise. In particular, it looked at trial methodology assessment procedures, the working relationship between the French National Agency of Drug Safety and Health Products (Agence Nationale de Sécurité du Médicament et des Produits de Santé, ANSM) and ethics committees during the authorization application evaluation phase, review of post-authorization/registration studies on medicinal products and medical devices, and data transparency.

  19. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.

    PubMed

    Lettice, Laura A; Horikoshi, Taizo; Heaney, Simon J H; van Baren, Marijke J; van der Linde, Herma C; Breedveld, Guido J; Joosse, Marijke; Akarsu, Nurten; Oostra, Ben A; Endo, Naoto; Shibata, Minoru; Suzuki, Mikio; Takahashi, Eiichi; Shinka, Toshikatsu; Nakahori, Yutaka; Ayusawa, Dai; Nakabayashi, Kazuhiko; Scherer, Stephen W; Heutink, Peter; Hill, Robert E; Noji, Sumihare

    2002-05-28

    Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation breakpoint in a PPD patient and a transgenic insertion site in the polydactylous mouse mutant sasquatch (Ssq). The genetic lesions in both lie within the same respective intron of the LMBR1/Lmbr1 gene, which resides approximately 1 Mb away from Shh. Genetic analysis of Ssq reveals that the Lmbr1 gene is incidental to the phenotype and that the mutation directly interrupts a cis-acting regulator of Shh. This regulator is most likely the target for generating PPD mutations in human.

  20. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly

    PubMed Central

    Lettice, Laura A.; Horikoshi, Taizo; Heaney, Simon J. H.; van Baren, Marijke J.; van der Linde, Herma C.; Breedveld, Guido J.; Joosse, Marijke; Akarsu, Nurten; Oostra, Ben A.; Endo, Naoto; Shibata, Minoru; Suzuki, Mikio; Takahashi, Eiichi; Shinka, Toshikatsu; Nakahori, Yutaka; Ayusawa, Dai; Nakabayashi, Kazuhiko; Scherer, Stephen W.; Heutink, Peter; Hill, Robert E.; Noji, Sumihare

    2002-01-01

    Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation breakpoint in a PPD patient and a transgenic insertion site in the polydactylous mouse mutant sasquatch (Ssq). The genetic lesions in both lie within the same respective intron of the LMBR1/Lmbr1 gene, which resides ≈1 Mb away from Shh. Genetic analysis of Ssq reveals that the Lmbr1 gene is incidental to the phenotype and that the mutation directly interrupts a cis-acting regulator of Shh. This regulator is most likely the target for generating PPD mutations in human. PMID:12032320

  1. Public Health Service Act, Rural Physician Training Grant Program, definition of "underserved rural community." Interim final rule with request for comment.

    PubMed

    2010-05-26

    This interim final rule (IFR) with request for comment is meant to comply with the statutory directive to issue a regulation defining "underserved rural community" for purposes of the Rural Physician Training Grant Program in section 749B of the Public Health Service Act, as amended by the Patient Protection and Affordable Care Act of 2010. This IFR is technical in nature. It will not change grant or funding eligibility for any other grant program currently available through the Office of Rural Health Policy (ORHP) or HRSA. For purposes of the Rural Physician Training Grant Program only, HRSA has combined existing definitions of "underserved" and "rural" by using the definition of rural utilized by the ORHP Rural Health Grant programs and the definition of "underserved" established by HRSA's Office of Shortage Designation (OSD) in the Bureau of Health Professions (BHPr).

  2. 26 CFR 1.706-2T - Temporary regulations; question and answer under the Tax Reform Act of 1984.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Partners and Partnerships § 1.706-2T Temporary regulations; question and answer under the Tax Reform Act of 1984. Question...

  3. 75 FR 44163 - Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ...-AB07 Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of... clarify conditions for industry compliance with the P&S Act and provide for a fairer market place. DATES... fairer market place. We have received comments asking for an extension of the comment period, and...

  4. Knowledge of the animal welfare act and animal welfare regulations influences attitudes toward animal research.

    PubMed

    Metzger, Mitchell M

    2015-01-01

    Recent public-opinion polls indicate that Americans have shown a decline in support for animal experimentation, and several reports suggest a relationship between people's knowledge of animal welfare regulations and their attitudes toward animal research. Therefore, this study was designed to assess respondent's knowledge of several provisions in the Animal Welfare Act (AWA) and Animal Welfare Regulations (AWR), and determine whether exposure to elements of this legislation would influence an individual's attitudes toward the use of animals in research. A survey was used to assess knowledge of animal research regulations and attitudes toward animal research from a sample of individuals recruited through Amazon's Mechanical Turk crowdsourcing marketplace. Results from study 1 confirmed the hypothesis that respondents had little knowledge of various federal regulations that govern animal research activities. Data from study 2 revealed that exposure to elements of the AWA and AWR influenced participants' attitudes toward the use of animals in research. These results suggest that providing information to the general public about the AWA and AWR that protect laboratory animals from abuse and neglect may help alleviate concerns about using animals in research settings.

  5. ISO New England: Results of Ancillary Service Pilot Programs, Alternative Technology Regulation Pilot Program and Demand Response Reserves Pilot Program

    SciTech Connect

    Lowell, Jon; Yoshimura, Henry

    2011-10-26

    This PowerPoint presentation compares performance of pilot program assets and generation resources in alternative technology regulation and demand response reserves for flywheels and residential electric thermal storage.

  6. 76 FR 71417 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Law Enforcement Agencies (LEA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Law Enforcement Agencies (LEA... provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching... above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of...

  7. 75 FR 68396 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match... of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503),...

  8. 75 FR 62623 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Internal Revenue Service (IRS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Internal Revenue Service (IRS.... SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503), amended the Privacy Act (5 U.S.C. 552a) by describing the conditions under which computer...

  9. 78 FR 54875 - Privacy Act of 1974; Computer Matching Program Between the Department of Education (ED) and the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... Privacy Act of 1974; Computer Matching Program Between the Department of Education (ED) and the Social... Computer Matching and Privacy Protection Act of 1988, the Computer Matching and Privacy Protections... Computer Matching and Privacy Protection Act of 1988, published in the Federal Register on June 19,...

  10. 75 FR 35847 - Privacy Act of 1974, Computer Matching Program-U.S. Small Business Administration and U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... ADMINISTRATION Privacy Act of 1974, Computer Matching Program--U.S. Small Business Administration and U.S... (Agreement) pursuant to section (o) of the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100- 503), and as amended by the Computer...

  11. 76 FR 12398 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Bureau of the Public Debt (BPD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Bureau of the Public Debt (BPD... provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Public Law (Pub. L.)...

  12. 77 FR 32709 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Homeland Security...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Homeland Security... the provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer.... SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Public Law...

  13. 75 FR 67755 - Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of Housing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... URBAN DEVELOPMENT Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of... the Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503), and the Office of... accordance with the Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503), as amended,...

  14. 78 FR 3474 - Privacy Act of 1974; Computer Matching Program Between the Office Of Personnel Management and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program Between the Office Of Personnel Management and...). SUMMARY: In accordance with the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer Matching.... B. OPM Computer Matches Subject to the Privacy Act We have taken action to ensure that all of...

  15. 76 FR 12397 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Bureau of the Public Debt (BPD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Bureau of the Public Debt (BPD... provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Public Law (Pub. L.)...

  16. 78 FR 69925 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Bureau of the Fiscal Service...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Bureau of the Fiscal Service... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503), amended the Privacy Act (5 U.S.C. 552a) by describing the conditions under which computer matching...

  17. 77 FR 5009 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Duke...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... object to a Clean Air Act (Act) Title V operating permit for Duke Energy Indiana--Edwardsport Generating... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Duke Energy Indiana--Edwardsport Generating Station AGENCY: Environmental Protection Agency (EPA)....

  18. 76 FR 12730 - Clean Air Act Operating Permit Program; Objection to State Operating Permit for U.S. Steel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Clean Air Act Operating Permit Program; Objection to State Operating Permit for U.S. Steel-Granite.... Steel--Granite City Works (USS). Sections 307(b) and 505(b)(2) of the Clean Air Act (Act) provide that...

  19. 75 FR 39575 - Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of Housing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... Budget (OMB) Guidelines on the Conduct of Matching Programs (June 19, 1989, 54 FR 25818), and OMB... was issued under the authority of the Budget and Accounting Act of 1921, as amended; the Budget and Accounting Act of 1950, as amended; the Debt Collection Act of 1982, as amended; and, the Deficit...

  20. 75 FR 51154 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of the Treasury...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of the Treasury... of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Pub. L. 100-503),...

  1. 75 FR 7648 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Veterans Affairs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Veterans Affairs... INFORMATION: A. General The Computer Matching and Privacy Protection Act of 1988 (Public Law (Pub. L.) 100-503), amended the Privacy Act (5 U.S.C. 552a) by describing the conditions under which computer...

  2. Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR).

    PubMed

    Solomon, Oz; Oren, Shirley; Safran, Michal; Deshet-Unger, Naamit; Akiva, Pinchas; Jacob-Hirsch, Jasmine; Cesarkas, Karen; Kabesa, Reut; Amariglio, Ninette; Unger, Ron; Rechavi, Gideon; Eyal, Eran

    2013-05-01

    Alternative mRNA splicing is a major mechanism for gene regulation and transcriptome diversity. Despite the extent of the phenomenon, the regulation and specificity of the splicing machinery are only partially understood. Adenosine-to-inosine (A-to-I) RNA editing of pre-mRNA by ADAR enzymes has been linked to splicing regulation in several cases. Here we used bioinformatics approaches, RNA-seq and exon-specific microarray of ADAR knockdown cells to globally examine how ADAR and its A-to-I RNA editing activity influence alternative mRNA splicing. Although A-to-I RNA editing only rarely targets canonical splicing acceptor, donor, and branch sites, it was found to affect splicing regulatory elements (SREs) within exons. Cassette exons were found to be significantly enriched with A-to-I RNA editing sites compared with constitutive exons. RNA-seq and exon-specific microarray revealed that ADAR knockdown in hepatocarcinoma and myelogenous leukemia cell lines leads to global changes in gene expression, with hundreds of genes changing their splicing patterns in both cell lines. This global change in splicing pattern cannot be explained by putative editing sites alone. Genes showing significant changes in their splicing pattern are frequently involved in RNA processing and splicing activity. Analysis of recently published RNA-seq data from glioblastoma cell lines showed similar results. Our global analysis reveals that ADAR plays a major role in splicing regulation. Although direct editing of the splicing motifs does occur, we suggest it is not likely to be the primary mechanism for ADAR-mediated regulation of alternative splicing. Rather, this regulation is achieved by modulating trans-acting factors involved in the splicing machinery.

  3. ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing.

    PubMed

    Royo, Hélène; Prosser, Haydn; Ruzankina, Yaroslava; Mahadevaiah, Shantha K; Cloutier, Jeffrey M; Baumann, Marek; Fukuda, Tomoyuki; Höög, Christer; Tóth, Attila; de Rooij, Dirk G; Bradley, Allan; Brown, Eric J; Turner, James M A

    2013-07-01

    In mammals, homologs that fail to synapse during meiosis are transcriptionally inactivated. This process, meiotic silencing, drives inactivation of the heterologous XY bivalent in male germ cells (meiotic sex chromosome inactivation [MSCI]) and is thought to act as a meiotic surveillance mechanism. The checkpoint protein ATM and Rad3-related (ATR) localizes to unsynapsed chromosomes, but its role in the initiation and maintenance of meiotic silencing is unknown. Here we show that ATR has multiple roles in silencing. ATR first regulates HORMA (Hop1, Rev7, and Mad2) domain protein HORMAD1/2 phosphorylation and localization of breast cancer I (BRCA1) and ATR cofactors ATR-interacting peptide (ATRIP)/topoisomerase 2-binding protein 1 (TOPBP1) at unsynapsed axes. Later, it acts as an adaptor, transducing signaling at unsynapsed axes into surrounding chromatin in a manner that requires interdependence with mediator of DNA damage checkpoint 1 (MDC1) and H2AFX. Finally, ATR catalyzes histone H2AFX phosphorylation, the epigenetic event leading to gene inactivation. Using a novel genetic strategy in which MSCI is used to silence a chosen gene in pachytene, we show that ATR depletion does not disrupt the maintenance of silencing and that silencing comprises two phases: The first is dynamic and reversible, and the second is stable and irreversible. Our work identifies a role for ATR in the epigenetic regulation of gene expression and presents a new technique for ablating gene function in the germline.

  4. Confinement regulates complex biochemical networks: initiation of blood clotting by "diffusion acting".

    PubMed

    Shen, Feng; Pompano, Rebecca R; Kastrup, Christian J; Ismagilov, Rustem F

    2009-10-21

    This study shows that environmental confinement strongly affects the activation of nonlinear reaction networks, such as blood coagulation (clotting), by small quantities of activators. Blood coagulation is sensitive to the local concentration of soluble activators, initiating only when the activators surpass a threshold concentration, and therefore is regulated by mass transport phenomena such as flow and diffusion. Here, diffusion was limited by decreasing the size of microfluidic chambers, and it was found that microparticles carrying either the classical stimulus, tissue factor, or a bacterial stimulus, Bacillus cereus, initiated coagulation of human platelet-poor plasma only when confined. A simple analytical argument and numerical model were used to describe the mechanism for this phenomenon: confinement causes diffusible activators to accumulate locally and surpass the threshold concentration. To interpret the results, a dimensionless confinement number, Cn, was used to describe whether a stimulus was confined, and a Damköhler number, Da(2), was used to describe whether a subthreshold stimulus could initiate coagulation. In the context of initiation of coagulation by bacteria, this mechanism can be thought of as "diffusion acting", which is distinct from "diffusion sensing". The ability of confinement and diffusion acting to change the outcome of coagulation suggests that confinement should also regulate other biological "on" and "off" processes that are controlled by thresholds.

  5. 75 FR 18251 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Internal Revenue Service (IRS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Internal Revenue Service (IRS... computer matching program that is scheduled to expire on March 31, 2010. SUMMARY: In accordance with the provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer...

  6. 77 FR 6620 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/the States); Match 6000 and 6003

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ the States); Match 6000 and 6003 AGENCY: Social Security Administration (SSA). ACTION: Notice of a renewal of an existing computer... Privacy Act, as amended, this notice announces a renewal of an existing computer matching program that...

  7. 78 FR 71591 - Privacy Act of 1974; Computer Matching Program between the U.S. Department of Education (ED) and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... Privacy Act of 1974; Computer Matching Program between the U.S. Department of Education (ED) and the U.S..., the Computer Matching and Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989), and OMB... hereby given of the renewal of the computer matching program between the U.S. Department of Education...

  8. 77 FR 24756 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Department of Labor (DOL))--Match... Privacy Act, as amended, this notice announces a renewal of an existing computer matching program that we... Counsel, SSA, as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and...

  9. 78 FR 12128 - Privacy Act of 1974; Computer Matching Program (SSA/Department of the Treasury, Internal Revenue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... ADMINISTRATION Privacy Act of 1974; Computer Matching Program (SSA/Department of the Treasury, Internal Revenue... Privacy Act, (5 U.S.C. 552a), this notice announces a renewal of an existing computer matching program..., as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy...

  10. 78 FR 54629 - Fisheries of the Exclusive Economic Zone Off Alaska; American Fisheries Act, Amendment 80 Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... under the American Fisheries Act (AFA), the Aleutian Islands pollock fishery, the Amendment 80 trawl...-Stevens Act) to the AFA, Aleutian Islands pollock fishery, Amendment 80 Program, CDQ Program, and the... participation by people who are knowledgeable about the AFA, Aleutian Islands pollock fishery, Amendment 80,...

  11. 76 FR 3209 - West Los Angeles VA Medical Center Veterans Programs Enhancement Act of 1998; Draft Master Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ...This Federal Register Notice announces an opportunity for public comment on the West Los Angeles (WLA) Department of Veterans Affairs (VA) Medical Center Veterans Programs Enhancement Act of 1998 (VPEA) Draft Master Plan (hereinafter referred to as the ``Draft Master Plan.'' The purpose of this plan is to satisfy the legislative mandate of the Veterans Programs Enhancement Act of 1998......

  12. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-Bacon Act labor standards? 672.545 Section 672.545 Employees' Benefits EMPLOYMENT AND TRAINING..., Costs, and Limitations § 672.545 Are YouthBuild programs subject to the Davis-Bacon Act labor standards? (a) YouthBuild programs and grantees are subject to Davis-Bacon labor standards requirements...

  13. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-Bacon Act labor standards? 672.545 Section 672.545 Employees' Benefits EMPLOYMENT AND TRAINING..., Costs, and Limitations § 672.545 Are YouthBuild programs subject to the Davis-Bacon Act labor standards? (a) YouthBuild programs and grantees are subject to Davis-Bacon labor standards requirements...

  14. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-Bacon Act labor standards? 672.545 Section 672.545 Employees' Benefits EMPLOYMENT AND TRAINING..., Costs, and Limitations § 672.545 Are YouthBuild programs subject to the Davis-Bacon Act labor standards? (a) YouthBuild programs and grantees are subject to Davis-Bacon labor standards requirements...

  15. Sperm is epigenetically programmed to regulate gene transcription in embryos

    PubMed Central

    Teperek, Marta; Simeone, Angela; Gaggioli, Vincent; Miyamoto, Kei; Allen, George E.; Erkek, Serap; Kwon, Taejoon; Marcotte, Edward M.; Zegerman, Philip; Bradshaw, Charles R.; Peters, Antoine H.F.M.; Gurdon, John B.; Jullien, Jerome

    2016-01-01

    For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the existence of epigenetic marks on sperm genes, and there are no functional tests supporting the role of sperm epigenetic marking on embryonic gene expression. Here, we show that sperm is epigenetically programmed to regulate embryonic gene expression. By comparing the development of sperm- and spermatid-derived frog embryos, we show that the programming of sperm for successful development relates to its ability to regulate transcription of a set of developmentally important genes. During spermatid maturation into sperm, these genes lose H3K4me2/3 and retain H3K27me3 marks. Experimental removal of these epigenetic marks at fertilization de-regulates gene expression in the resulting embryos in a paternal chromatin-dependent manner. This demonstrates that epigenetic instructions delivered by the sperm at fertilization are required for correct regulation of gene expression in the future embryos. The epigenetic mechanisms of developmental programming revealed here are likely to relate to the mechanisms involved in transgenerational transmission of acquired traits. Understanding how parental experience can influence development of the progeny has broad potential for improving human health. PMID:27034506

  16. Environmental Guidance Program reference book: Toxic substances control act. Revision 7

    SciTech Connect

    1994-12-01

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  17. Toxic Substances Control Act. Environmental Guidance Program Reference Book: Revision 6

    SciTech Connect

    Not Available

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  18. Clean Water Act (excluding Section 404). Environmental guidance program reference book: Revision 6

    SciTech Connect

    Not Available

    1993-01-15

    This Reference Book contains a current copy of the Clean Water Act (excluding Section 404) and those regulations that implement the statutes and appear to be most relevant to US Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  19. PVREG - A photovoltaic voltage regulation investigation tool: Program reference manual

    SciTech Connect

    Garrett, D.L.; Sims, T.R.; Jones, R.A.; Jeter, S.M.

    1989-06-01

    This manual provides information for installing and maintaining the computer program PVREG, a program developed to study the impact of distributed photovoltaic systems on the voltage regulation of distribution systems. The manual describes installation on the Apollo workstation or the IBM PC-AT (or compatible), but the instructions and code description should be general enough to assist installation on other computers, also. The manual assumes that the user is well acquainted with the computer on which the program is to operate and with the operating system of that computer. The manual describes the program structure and models in detail and provides step-by-step installation instructions for both the Apollo and AT-compatible computers. 9 figs., 11 tabs.

  20. Congress has yet to act on key programs; HOPWA may take hit.

    PubMed

    1999-08-20

    The U.S. Congress went on recess without passing key HIV spending programs. Committees in both the House and the Senate delayed action on the Labor, Health and Human Services, and Education appropriations bill for fiscal 2000 until after the break. This bill covers 90 percent of discretionary HIV spending by the Federal government, including $1.4 billion for the Ryan White CARE Act and $1.8 billion for AIDS research at the National Institutes of Health. A $10 million spending cut for the Housing Opportunities for People with AIDS program was proposed. In addition, the House voted to prohibit the District of Columbia from spending any money to operate needle exchange programs. President Clinton has proposed $175.4 million in spending increases for discretionary HIV programs for the next fiscal year, which would be an increase of 3.2 percent over the current year.

  1. MecA Protein Acts as a Negative Regulator of Genetic Competence in Streptococcus mutans

    PubMed Central

    Tian, Xiao-Lin; Dong, Gaofeng; Liu, Tianlei; Gomez, Zubelda A.; Wahl, Astrid; Hols, Pascal

    2013-01-01

    Streptococcus mutans develops competence for genetic transformation through a complex network that receives inputs from at least two signaling peptides, competence-stimulating peptide (CSP) and sigX-inducing peptide (XIP). The key step of competence induction is the transcriptional activation of comX, which encodes an alternative sigma factor, SigX (σX), controlling the expression of late competence genes essential for DNA uptake and recombination. In this study, we provide evidence that MecA acts as a negative regulator in the posttranslational regulation of SigX in S. mutans. Using luxAB transcriptional reporter strains, we demonstrate that MecA represses the expression of late competence genes in S. mutans grown in a complex medium that is subpermissive for competence induction by CSP. The negative regulation of competence by MecA requires the presence of a functional SigX. Accordingly, inactivation of MecA results in a prolonged competence state of S. mutans under this condition. We have also found that the AAA+ protease ClpC displays a similar repressing effect on late competence genes, suggesting that both MecA and ClpC function coordinately to regulate competence in the same regulatory circuit in S. mutans. This suggestion is strongly supported by the results of bacterial two-hybrid assays, which demonstrate that MecA interacts with both SigX and ClpC, forming a ternary SigX-MecA-ClpC complex. Western blot analysis also confirms that inactivation of MecA or ClpC results in the intracellular accumulation of the SigX in S. mutans. Together, our data support the notion that MecA mediates the formation of a ternary SigX-MecA-ClpC complex that sequesters SigX and thereby negatively regulates genetic competence in S. mutans. PMID:24039267

  2. Women’s Educational Equity Act: A Review of Program Goals and Strategies Needed,

    DTIC Science & Technology

    1994-12-01

    This report responds to your request that we review the Department of Education’s Women’s Educational Equity Act (WEEA) Program. First authorized by... educational equity for women, (2) help educational institutions meet the requirements of title IX of the Education Amendments of 1972 prohibiting sex...discrimination in all educational institutions receiving federal funds, and (3) provide educational equity for women and girls who suffer multiple

  3. 46 CFR 391.1 - Scope of section 607 of the Act and the regulations in this part.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Scope of section 607 of the Act and the regulations in this part. 391.1 Section 391.1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS UNDER PUBLIC LAW 91-469 FEDERAL INCOME TAX ASPECTS OF THE CAPITAL CONSTRUCTION FUND § 391.1...

  4. Epithelial IL-1R2 acts as a homeostatic regulator during remission of ulcerative colitis

    PubMed Central

    Mora-Buch, R; Dotti, I; Planell, N; Calderón-Gómez, E; Jung, P; Masamunt, M C; Llach, J; Ricart, E; Batlle, E; Panés, J; Salas, A

    2016-01-01

    Ulcerative colitis (UC) is a chronic intestinal inflammatory disease that may undergo periods of activity followed by remission. We aimed to identify the endogenous regulatory mechanisms that may promote disease remission. Transcriptional and protein analysis of the intestinal mucosa revealed that the IL-1 decoy receptor, interleukin-1 receptor type 2 (IL1R2), was upregulated in remission compared with active UC and controls. We identified epithelial cells as being responsible for increased IL-1R2 production during remission. Expression of IL1R2 was negatively regulated by Wnt/beta-catenin signals in colonic crypts or epithelial stem cell cultures; accordingly, epithelial stem cells upregulated IL-1R2 upon differentiation. Blocking IL-1R2 in isolated colonic crypt cultures of UC patients in remission and T-cell cultures stimulated with biopsy supernatant from UC patients in remission boosted IL-1β-dependent production of inflammation-related cytokines. Finally, IL1R2 transcription was significantly lower in patients that relapsed during a 1-year follow-up period compared with those in endoscopic remission. Collectively, our results reveal that the IL-1/IL-1R2 axis is differentially regulated in the remitting intestinal mucosa of UC patients. We hypothesize that IL-1R2 in the presence of low concentrations of IL-1β may act locally as a regulator of intestinal homeostasis. PMID:26530134

  5. Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis

    PubMed Central

    Rogers, Edward M.; Spracklen, Andrew J.; Bilancia, Colleen G.; Sumigray, Kaelyn D.; Allred, S. Colby; Nowotarski, Stephanie H.; Schaefer, Kristina N.; Ritchie, Benjamin J.; Peifer, Mark

    2016-01-01

    Abelson family kinases (Abls) are key regulators of cell behavior and the cytoskeleton during development and in leukemia. Abl’s SH3, SH2, and tyrosine kinase domains are joined via a linker to an F-actin–binding domain (FABD). Research on Abl’s roles in cell culture led to several hypotheses for its mechanism of action: 1) Abl phosphorylates other proteins, modulating their activity, 2) Abl directly regulates the cytoskeleton via its cytoskeletal interaction domains, and/or 3) Abl is a scaffold for a signaling complex. The importance of these roles during normal development remains untested. We tested these mechanistic hypotheses during Drosophila morphogenesis using a series of mutants to examine Abl’s many cell biological roles. Strikingly, Abl lacking the FABD fully rescued morphogenesis, cell shape change, actin regulation, and viability, whereas kinase-dead Abl, although reduced in function, retained substantial rescuing ability in some but not all Abl functions. We also tested the function of four conserved motifs in the linker region, revealing a key role for a conserved PXXP motif known to bind Crk and Abi. We propose that Abl acts as a robust multidomain scaffold with different protein motifs and activities contributing differentially to diverse cellular behaviors. PMID:27385341

  6. Audit Report on "The Department of Energy's American Recovery and Reinvestment Act -- Florida State Energy Program"

    SciTech Connect

    2010-06-01

    The Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE) provides grants to states, territories, and the District of Columbia to support their energy priorities through the State Energy Program (SEP). The SEP provides Federal financial assistance to carry out energy efficiency and renewable energy projects that meet each state's unique energy needs while also addressing national goals such as energy security. Federal funding is based on a grant formula that takes into account population and energy consumption. The SEP emphasizes the state's role as the decision maker and administrator for the program. The American Recovery and Reinvestment Act of 2009 (Recovery Act) expanded the SEP, authorizing $3.1 billion in grants. Based on existing grant formulas and after reviewing state-level plans, EERE made awards to states. The State of Florida's Energy Office (Florida) was allocated $126 million - a 90-fold increase over Florida's average annual SEP grant of $1.4 million. Per the Recovery Act, this funding must be obligated by September 30, 2010, and spent by April 30, 2012. As of March 10, 2010, Florida had expended $13.2 million of the SEP Recovery Act funds. Florida planned to use its grant funds to undertake activities that would preserve and create jobs; save energy; increase renewable energy sources; and, reduce greenhouse gas emissions. To accomplish Recovery Act objectives, states could either fund new or expand existing projects. As a condition of the awards, EERE required states to develop and implement sound internal controls over the use of Recovery Act funds. Based on the significant increase in funding from the Recovery Act, we initiated this review to determine whether Florida had internal controls in place to provide assurance that the goals of the SEP and Recovery Act will be met and accomplished efficiently and effectively. We identified weaknesses in the implementation of SEP Recovery Act projects that have adversely impacted

  7. 75 FR 51420 - Removing Regulations Implementing the Fish and Wildlife Conservation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... Wildlife Conservation Act AGENCY: Fish and Wildlife Service, Interior. ACTION: Final rule. SUMMARY: We, the... Wildlife Conservation Act of 1980. The Act authorized financial and technical assistance to States to... Wildlife Conservation Act of 1980 (16 U.S.C. 2901-2911). This act authorized the Service to give...

  8. Environmental Guidance Program Reference Book: Endangered Species Act and the Fish and Wildlife Coordination Act. Revision 5

    SciTech Connect

    Not Available

    1989-01-01

    The Endangered Species Act and the Fish and Wildlife Coordination Act are major federal statutes designed to protect plant and animal resources from adverse effects due to development projects. Both Acts require consultation with wildlife authorities prior to committing resources to certain types of projects. The purposes and requirements of the two statutes are summarized in the following subsections. Also presented is a list of contacts in the regional and field offices of the US Fish and Wildlife Service.

  9. atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain

    NASA Technical Reports Server (NTRS)

    Hassan, B. A.; Bermingham, N. A.; He, Y.; Sun, Y.; Jan, Y. N.; Zoghbi, H. Y.; Bellen, H. J.

    2000-01-01

    Drosophila atonal (ato) is the proneural gene of the chordotonal organs (CHOs) in the peripheral nervous system (PNS) and the larval and adult photoreceptor organs. Here, we show that ato is expressed at multiple stages during the development of a lineage of central brain neurons that innervate the optic lobes and are required for eclosion. A novel fate mapping approach shows that ato is expressed in the embryonic precursors of these neurons and that its expression is reactivated in third instar larvae (L3). In contrast to its function in the PNS, ato does not act as a proneural gene in the embryonic brain. Instead, ato performs a novel function, regulating arborization during larval and pupal development by interacting with Notch.

  10. Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis.

    PubMed

    Le Goff, Emilie; Martinand-Mari, Camille; Martin, Marianne; Feuillard, Jérôme; Boublik, Yvan; Godefroy, Nelly; Mangeat, Paul; Baghdiguian, Stephen; Cavalli, Giacomo

    2015-08-14

    The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial expression domains of their target genes, particularly of Hox genes, starting from mid embryogenesis. The Enhancer of zeste [E(z)] PcG protein is the catalytic subunit of the PRC2 complex, which silences its targets via deposition of the H3K27me3 mark. Here, we studied the ascidian Ciona intestinalis counterpart of E(z). Ci-E(z) is detected by immunohistochemistry as soon as the 2- and 4-cell stages as a cytoplasmic form and becomes exclusively nuclear thereafter, whereas the H3K27me3 mark is detected starting from the gastrula stage and later. Morpholino invalidation of Ci-E(z) leads to the total disappearance of both Ci-E(z) protein and its H3K27me3 mark. Ci-E(z) morphants display a severe phenotype. Strikingly, the earliest defects occur at the 4-cell stage with the dysregulation of cell positioning and mitotic impairment. At later stages, Ci-E(z)-deficient embryos are affected by terminal differentiation defects of neural, epidermal and muscle tissues, by the failure to form a notochord and by the absence of caudal nerve. These major phenotypic defects are specifically rescued by injection of a morpholino-resistant Ci-E(z) mRNA, which restores expression of Ci-E(z) protein and re-deposition of the H3K27me3 mark. As observed by qPCR analyses, Ci-E(z) invalidation leads to the early derepression of tissue-specific developmental genes, whereas late-acting developmental genes are generally down-regulated. Altogether, our results suggest that Ci-E(z) plays a major role during embryonic development in Ciona intestinalis by silencing early-acting developmental genes in a Hox-independent manner.

  11. Extracellular calcium acts as a “third messenger” to regulate enzyme and alkaline secretion

    PubMed Central

    Caroppo, Rosa; Gerbino, Andrea; Fistetto, Gregorio; Colella, Matilde; Debellis, Lucantonio; Hofer, Aldebaran M.; Curci, Silvana

    2004-01-01

    It is generally assumed that the functional consequences of stimulation with Ca2+-mobilizing agonists are derived exclusively from the second messenger action of intracellular Ca2+, acting on targets inside the cells. However, during Ca2+ signaling events, Ca2+ moves in and out of the cell, causing changes not only in intracellular Ca2+, but also in local extracellular Ca2+. The fact that numerous cell types possess an extracellular Ca2+ “sensor” raises the question of whether these dynamic changes in external [Ca2+] may serve some sort of messenger function. We found that in intact gastric mucosa, the changes in extracellular [Ca2+] secondary to carbachol-induced increases in intracellular [Ca2+] were sufficient and necessary to elicit alkaline secretion and pepsinogen secretion, independent of intracellular [Ca2+] changes. These findings suggest that extracellular Ca2+ can act as a “third messenger” via Ca2+ sensor(s) to regulate specific subsets of tissue function previously assumed to be under the direct control of intracellular Ca2+. PMID:15240573

  12. 7 CFR 1940.328 - State Environmental Policy Acts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true State Environmental Policy Acts. 1940.328 Section 1940... (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL Environmental Program § 1940.328 State Environmental Policy Acts. (a) Numerous States have enacted environmental policy acts or regulations similar to...

  13. Preliminary Audit Report on "Management Controls over the Commonwealth of Virginia's Efforts to Implement the American Recovery and Reinvestment Act Weatherization Assistance Program"

    SciTech Connect

    2010-05-01

    the Recovery Act; (2) Reviewed documentation supporting sub-grantee requests for reimbursements to verify the accuracy of amounts charged; (3) Periodically reconciled amounts paid to sub-grantees to the actual cost to weatherize units; (4) Maintained vehicle and equipment inventories as required by Federal regulations and state and Federal program directives; and (5) Accurately reported Weatherization Program results to the Department. Exacerbating weaknesses in DHCD's financial controls, the Department's most recent program monitoring visit to Virginia, made in 2008 before passage of the Recovery Act, did not include a required financial review. Hence, the financial control weaknesses discussed above were not detected and had not been addressed. As described in this report, these control and reporting weaknesses increase the risk that Recovery Act objectives may not be achieved and that fraud, waste or abuse can occur and not be detected in this critically important program.

  14. Flavonoids act as negative regulators of auxin transport in vivo in arabidopsis

    NASA Technical Reports Server (NTRS)

    Brown, D. E.; Rashotte, A. M.; Murphy, A. S.; Normanly, J.; Tague, B. W.; Peer, W. A.; Taiz, L.; Muday, G. K.

    2001-01-01

    Polar transport of the plant hormone auxin controls many aspects of plant growth and development. A number of synthetic compounds have been shown to block the process of auxin transport by inhibition of the auxin efflux carrier complex. These synthetic auxin transport inhibitors may act by mimicking endogenous molecules. Flavonoids, a class of secondary plant metabolic compounds, have been suggested to be auxin transport inhibitors based on their in vitro activity. The hypothesis that flavonoids regulate auxin transport in vivo was tested in Arabidopsis by comparing wild-type (WT) and transparent testa (tt4) plants with a mutation in the gene encoding the first enzyme in flavonoid biosynthesis, chalcone synthase. In a comparison between tt4 and WT plants, phenotypic differences were observed, including three times as many secondary inflorescence stems, reduced plant height, decreased stem diameter, and increased secondary root development. Growth of WT Arabidopsis plants on naringenin, a biosynthetic precursor to those flavonoids with auxin transport inhibitor activity in vitro, leads to a reduction in root growth and gravitropism, similar to the effects of synthetic auxin transport inhibitors. Analyses of auxin transport in the inflorescence and hypocotyl of independent tt4 alleles indicate that auxin transport is elevated in plants with a tt4 mutation. In hypocotyls of tt4, this elevated transport is reversed when flavonoids are synthesized by growth of plants on the flavonoid precursor, naringenin. These results are consistent with a role for flavonoids as endogenous regulators of auxin transport.

  15. 78 FR 40541 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA)-Match Number 1014

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA)--Match Number 1014 AGENCY: Social Security Administration (SSA). ] ACTION: Notice of a renewal of an existing computer matching program that... amended, this notice announces a renewal of an existing computer matching program that we are...

  16. 76 FR 5235 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA Internal Match)-Match Number 1014

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA Internal Match)--Match Number 1014 AGENCY: Social Security Administration (SSA) ACTION: Notice of a new computer matching program. SUMMARY... computer matching program that we are conducting with ourselves. DATES: We will file a report of...

  17. 78 FR 69926 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Centers for Medicare & Medicaid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Centers for Medicare & Medicaid... renewal of an existing computer matching program that will expire on October 16, 2013. SUMMARY: In... computer matching program that we conduct with CMS. DATES: We will file a report of the subject...

  18. 76 FR 19757 - The Federal Student Aid Programs Under Title IV of the Higher Education Act of 1965, as Amended

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... Federal Student Aid Programs Under Title IV of the Higher Education Act of 1965, as Amended AGENCY... Assurance Program. SUMMARY: The Secretary of Education invites institutions of higher education that may wish to participate in the Quality Assurance Program, under section 487A(a) of the Higher Education...

  19. 75 FR 9012 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/U.S. Department of Health and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ U.S. Department of Health and... existing computer matching program that is scheduled to expire on March 19, 2010. SUMMARY: In accordance... computer matching program that we are currently conducting with OCSE. DATES: We will file a report of...

  20. Allowance trading under the Clean Air Act: Who should regulate, and when?

    SciTech Connect

    Lock, R.

    1993-07-01

    The goal of this paper is to explore how compliance with the Clean Air Act Amendments of 1990 (CAAA), especially Title IV and emission trading under it, will affect the current relationship between state and federal regulation. It is difficult, with the limited experience we have had under Title IV, to be definitive about or to be a very strong advocate of too many policy positions. What may be most helpful at this point is to identify where the difficult issues in state/federal relations might arise; and then to explore ways in which tensions might be either avoided or resolved. One anticipated conclusion is that a traditional regulatory mindset could be very destructive if applied to this new area of oversight without due sensitivity to what Congress is trying to achieve in Title IV. That concern pervaded the early legislative debates; and it persists today. Title IV presents some unique challenges to state regulators and will require some creative solutions and fresh thinking if the goals of Congress are to be realized and the full benefits that allowance trading can offer are to be reaped by electricity consumers. In the ultimate analysis, Title IV amounts to a massive internalization of the external costs imposed on society by acid rain deposition. (This places in serious question the notion of additional externality {open_quotes}adders{close_quotes} for sulfur dioxide (SO{sub 2}) and nitrous oxide (NO{sub x}) at the state level for utility supply planning purposes.) The whole point of Title IV is to give those directly charged with compliance, namely power producers, the maximum flexibility to pursue least-cost compliance solutions. Perhaps the biggest single factor in how well they do this will be how state regulators respond to their compliance and allowance trading initiatives.

  1. The implications of the ADA Amendments Act of 2008 for residency training program administration.

    PubMed

    Regenbogen, Alexandra; Recupero, Patricia R

    2012-01-01

    The Americans with Disabilities Act (ADA) is rarely invoked by medical residents in training. Dr. Martin Jakubowski, a family medicine resident with Asperger's disorder, was dismissed for communicating poorly with patients, peers, and supervisors and for issuing dangerous medical orders. In an attempt to become reinstated, he sued under the ADA (Jakubowski v. The Christ Hospital), arguing that the program had failed to make reasonable accommodation for his disability. The Sixth Circuit Court of Appeals ruled in favor of the hospital, finding that although the doctor was disabled under the ADA, he had failed to demonstrate that he was otherwise qualified for the position. This article comments on the ADA Amendments Act of 2008, the Equal Employment Opportunity Commission (EEOC) guidelines from 2011 and their application to medical residency training, and the Accreditation Council for Graduate Medical Education (ACGME) core competencies as essential job functions.

  2. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance...

  3. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance...

  4. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance...

  5. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance...

  6. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance...

  7. Montgomery County Public Schools Summer VIEW Program: A Transition-to-Work Program for Special Education Students Funded through the Job Training Partnership Act. Final Report.

    ERIC Educational Resources Information Center

    Meissner, Margit

    This paper presents the final report on the 1988 High School Vocational Interest Exploration Workshop (VIEW) program of the Montgomery County (Maryland) Public Schools. The 4-week summer program, funded through the Job Training Partnership Act, involved Level 4 special education students, aged 14 to 19. The program provided 1-week minicourses in…

  8. Environmental Guidance Program Reference Book: Comprehensive Environmentally Response, Compensation, and Liability Act

    SciTech Connect

    Not Available

    1991-12-31

    This Reference Book contains a current copy of the Comprehensive Environmental Response Compensation, and Liability Act and those regulations that implement the statute and appear to be most relevant to Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (FTS 896-2609 or Commercial 202/586-2609).

  9. Transcriptional programs regulated by both LEAFY and APETALA1 at the time of flower formation.

    PubMed

    Winter, Cara M; Yamaguchi, Nobutoshi; Wu, Miin-Feng; Wagner, Doris

    2015-09-01

    Two key regulators of the switch to flower formation and of flower patterning in Arabidopsis are the plant-specific helix-turn-helix transcription factor LEAFY (LFY) and the MADS box transcription factor APETALA1 (AP1). The interactions between these two transcriptional regulators are complex. AP1 is both a direct target of LFY and can act in parallel with LFY. Available genetic and molecular evidence suggests that LFY and AP1 together orchestrate the switch to flower formation and early events during flower morphogenesis by altering transcriptional programs. However, very little is known about target genes regulated by both transcription factors. Here, we performed a meta-analysis of public datasets to identify genes that are likely to be regulated by both LFY and AP1. Our analyses uncovered known and novel direct LFY and AP1 targets with a role in the control of onset of flower formation. It also identified additional families of proteins and regulatory pathways that may be under transcriptional control by both transcription factors. In particular, several of these genes are linked to response to hormones, to transport and to development. Finally, we show that the gibberellin catabolism enzyme ELA1, which was recently shown to be important for the timing of the switch to flower formation, is positively feedback-regulated by AP1. Our study contributes to the elucidation of the regulatory network that leads to formation of a vital plant organ system, the flower.

  10. Some impacts of the 1990 Clean Air Act and state clean-air regulations on the fertilizer industry

    SciTech Connect

    Breed, C.E.; Kerns, O.S.

    1992-12-01

    The Clean Air Act amendments of 1990 will intensify national efforts to reduce air pollution. They will have major impacts an governmental agencies and on industrial and commercial facilities throughout the country. As with other industries, it is essential for fertilizer dealers and producers to understand how these changes to the Clean Air Act can significantly change the way they do business. This paper is proffered as an overview of ways in which the 1990 amendments to the Clean Air Act may impact the fertilizer industry. The nonattainment, toxics, and permit provisions of the amended act will be three areas of particular concern to the fertilizer industry. Implementation of the new regulatory requirements of this legislation promises to be a long and onerous process for all concerned. However, it appears that state and local regulations may have a much more profound impact on the fertilizer industry than the new Clean Air Act.

  11. Some impacts of the 1990 Clean Air Act and state clean-air regulations on the fertilizer industry

    SciTech Connect

    Breed, C.E.; Kerns, O.S.

    1992-12-31

    The Clean Air Act amendments of 1990 will intensify national efforts to reduce air pollution. They will have major impacts on governmental agencies and on industrial and commercial facilities throughout the country. As with other industries, it is essential for fertilizer dealers and producers to understand how these changes to the Clean Air Act can significantly change the way they do business. This paper is proffered as an overview of ways in which the 1990 amendments to the Clean Air Act may impact the fertilizer industry. The nonattainment, toxics, and permit provisions of the amended act will be three areas of particular concern to the fertilizer industry. Implementation of the new regulatory requirements of this legislation promises to be a long and onerous process for all concerned. However, it appears that state and local regulations may have a much more profound impact on the fertilizer industry than the new Clean Air Act.

  12. 77 FR 72581 - Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ...The U.S. Office of Personnel Management (OPM) is issuing a proposed rule to implement the Multi-State Plan Program (MSPP). OPM is establishing the MSPP pursuant to the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act of 2010, referred to collectively as the Affordable Care Act. Through contracts with OPM, health insurance issuers will......

  13. 76 FR 32990 - Workforce Investment Act of 1998 (WIA); Notice of Incentive Funding Availability for Program Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... Employment and Training Administration Workforce Investment Act of 1998 (WIA); Notice of Incentive Funding Availability for Program Year (PY) 2009 Performance; Correction AGENCY: Employment and Training Administration, Labor. ACTION: Notice; correction. SUMMARY: The Employment and Training Administration (ETA)...

  14. Development of Stitched, Braided and Woven Composite Structures in the ACT Program and at Langley Research Center

    NASA Technical Reports Server (NTRS)

    Dow, Marvin B.; Dexter, H. Benson

    1997-01-01

    Summary results are presented from the research conducted on woven, braided, knitted and stitched (textile) composites at the Langley Research Center and under the NASA Advanced Composites Technology (ACT) Program in the period from 1985 to 1997. The report also includes an annotated bibliography of 270 U.S. publications on textile composites (with their abstracts). Two major research areas are discussed: (1) the general research in textile composites performed throughout the period under the direction of the Langley Research Center and (2) the development of textile composite aircraft structures by industry under the NASA ACT Program. The annotated bibliography is organized in three subsections: (1) general textiles R&D under the auspices of Langley, (2) ACT Program development of textile structural components, and (3) textiles research by individuals and organizations not associated with the ACT Program. An author index is provided for the reports and documents.

  15. 78 FR 23885 - Federal Seed Act Program; Request for Extension and Revision of a Currently Approved Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... Agricultural Marketing Service Federal Seed Act Program; Request for Extension and Revision of a Currently Approved Information Collection AGENCY: Agricultural Marketing Service, USDA. ACTION: Request for comments... announces the Agricultural Marketing Service's (AMS) intention to request approval, from the Office...

  16. 75 FR 29447 - Public Health Service Act, Rural Physician Training Grant Program, Definition of “Underserved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... 29447-29451] [FR Doc No: 2010-12557] DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 5a RIN 0906-AA86 Public Health Service Act, Rural Physician Training Grant Program, Definition of ``Underserved... 749B of the Public Health Service Act. Sec. 5a.3 Definition of Underserved Rural Community....

  17. 77 FR 42492 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for... of final order on petition to object to a state operating permit. SUMMARY: Pursuant to Clean Air Act... permit issued by the Kentucky Division for Air Quality (KDAQ) to Kentucky Syngas, LLC (KSG) for...

  18. 75 FR 63524 - Computer Matching and Privacy Protection Act of 1988; Report of Matching Program: RRB and State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Computer Matching and Privacy Protection Act of 1988; Report of Matching Program: RRB and State Medicare Agencies AGENCY: Railroad Retirement Board (RRB). ACTION: Notice of records used in computer matching... required by the Computer Matching and Privacy Protection Act of ] 1988, the RRB is issuing a public...

  19. 78 FR 37647 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Railroad Retirement Board (RRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Railroad Retirement Board (RRB... of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching..., as shown above. SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy...

  20. 78 FR 34678 - Privacy Act of 1974, as Amended; Notice of Computer Matching Program (Railroad Retirement Board...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... Privacy Act of 1974, as Amended; Notice of Computer Matching Program (Railroad Retirement Board and Social... Privacy Act of 1974, as amended, the RRB is issuing public notice of its renewal of an ongoing computer....grant@rrb.gov . SUPPLEMENTARY INFORMATION: A. General The Computer Matching and Privacy Protection...

  1. Developing a Performance Management System for a Federal Public Health Program: The Ryan White CARE ACT Titles I and II.

    ERIC Educational Resources Information Center

    Kates, Jennifer; Marconi, Katherine; Mannle, Thomas E., Jr.

    2001-01-01

    Describes an approach to introducing performance measurement into a large federal health program, the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act, in response to the government Performance and Results Act. Also discusses characteristics of the HIV/AIDS epidemic that present unique challenges for performance measurement. (SLD)

  2. Perceptions Re: Adequacy and Effectiveness of the JTPA and V.E. Perkins Act Programs in Illinois. Report 23.

    ERIC Educational Resources Information Center

    Black, Hartzel; And Others

    A study was conducted in Illinois to determine the perceptions of "grassroots" personnel who have responsibility for administering programs authorized under both the Job Training Partnership Act (JTPA) and the Carl D. Perkins Vocational Education Act. Questionnaires were mailed to regional delivery system directors, community college…

  3. 40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...

  4. 40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...

  5. 40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2348 National Highway Systems Designation Act Motor Vehicle Inspection..., 1999, the State of Utah submitted an evaluation of the Utah County inspection and maintenance...

  6. Retargeting a Dual-Acting sRNA for Multiple mRNA Transcript Regulation.

    PubMed

    Lahiry, Ashwin; Stimple, Samuel D; Wood, David W; Lease, Richard A

    2017-01-24

    Multitargeting small regulatory RNAs (sRNAs) represent a potentially useful tool for metabolic engineering applications. Natural multitargeting sRNAs govern bacterial gene expression by binding to the translation initiation regions of protein-coding mRNAs through base pairing. We designed an Escherichia coli based genetic system to create and assay dual-acting retargeted-sRNA variants. The variants can be assayed for coordinate translational regulation of two alternate mRNA leaders fused to independent reporter genes. Accordingly, we began with the well-characterized E. coli native DsrA sRNA. The merits of using DsrA include its well-characterized separation of function into two independently folded stem-loop domains, wherein alterations at one stem do not necessarily abolish activity at the other stem. Expression of the sRNA and each reporter mRNA was independently controlled by small inducer molecules, allowing precise quantification of the regulatory effects of each sRNA:mRNA interaction in vivo with a microtiter plate assay. Using this system, we semirationally designed DsrA variants screened in E. coli for their ability to regulate key mRNA leader sequences from the Clostridium acetobutylicum n-butanol synthesis pathway. To coordinate intervention at two points in a metabolic pathway, we created bifunctional sRNA prototypes by combining sequences from two singly retargeted DsrA variants. This approach constitutes a platform for designing sRNAs to specifically target arbitrary mRNA transcript sequences, and thus provides a generalizable tool for retargeting and characterizing multitarget sRNAs for metabolic engineering.

  7. 77 FR 11367 - Defense Federal Acquisition Regulation Supplement; Extension of the Test Program for Negotiation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... Regulation Supplement; Extension of the Test Program for Negotiation of Comprehensive Small Business... Acquisition Regulation Supplement to extend the program period for the DoD Test Program for Negotiation of...). Section 866 amends the DoD Test Program for Negotiation of Comprehensive Small Business...

  8. Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10). Environmental Guidance Program Reference Book, Revision 4

    SciTech Connect

    1992-03-01

    This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609).

  9. Recovery Act Education Programs: Funding Retained Teachers, but Education Could More Consistently Communicate Stabilization Monitoring Issues. Report to Congress. GAO-11-804

    ERIC Educational Resources Information Center

    Scott, George A.

    2011-01-01

    The American Recovery and Reinvestment Act of 2009 (Recovery Act) provided $70.3 billion for three education programs--the State Fiscal Stabilization Fund (SFSF); Title I, Part A of the Elementary and Secondary Education Act (Title I); and Individuals with Disabilities Education Act (IDEA), Part B. One goal of the Recovery Act was to save and…

  10. Pyrethroid mode(s) of action in the context of Food Quality Protection Act (FQPA) regulation.

    PubMed

    Gammon, Derek W; Leggett, Michael F; Clark, John M

    2011-04-13

    A Scientific Advisory Panel (SAP) in June 2009 concluded that a common mode of action existed for pyrethroids, with two subgroups. The purpose of this SAP was to advise the U.S. Environmental Protection Agency on the validity of regulation of pyrethroids as a single class under the Food Quality Protection Act of 1996. Two types of pyrethroid action were first described for clinical signs in the rat and clinical signs/nerve effects in the cockroach. In insects, Type I clinical signs correlate with repetitive firing in nerve axons, especially fine sensory axons. The Na(+) inward current is via a TTX-sensitive voltage-gated sodium channel (VGSC). Type II (α-CN) effects on VGSCs do not include repetitive firing following stimulation in these axons. Instead, Type II effects on VGSCs include prolonged Na(+) tail currents along with depolarization of nerve membrane. Other Type II effects have been measured on VG Ca(2+) and K(+) channels and VG and GABA-activated Cl(-) channels. In conclusion, in vivo pyrethroid effects in mammals should be linked with specific channel effects, allowing the use of specific clinical signs or ion channel effects for pyrethroid risk assessment.

  11. Impact of Clean Air Act Regulations on Nitrogen Fate and Transport in the Neuse River Basin

    NASA Astrophysics Data System (ADS)

    Gabriel, M. C.; Knightes, C. D.; Dennis, R. L.; Cooter, E. J.

    2012-12-01

    This study investigated impacts of Clean Air Act Amendment (CAAA) NOx emissions regulations on the fate and transport of nitrogen for two watersheds in the Neuse River Basin, North Carolina, USA from 1990 to 2020. The Soil and Water Assessment Tool (SWAT) and the Community Multi-scale Air Quality (CMAQ) modeling system were used. CMAQ simulated atmospheric chemical transport and nitrogen deposition. This data was entered into SWAT which simulated watershed hydrology and water quality. Two cases were investigated: one that incorporates CAAA regulatory emissions controls in CMAQ simulation (with) and a second case that does not (without). SWAT model results forecasted a 70% decrease in inorganic nitrogen discharge from the Little River watershed and a 50% decrease for the Nahunta watershed by 2020 under the emission control (with) scenario. Denitrification and plant nitrogen uptake played important roles in nitrogen discharge from each watershed. The nitrogen discharge response time following a change in atmospheric nitrogen deposition was 4 years for the Nahunta watershed and 2 years for the Little River watershed. The longer response time for Nahunta is primarily due to a higher percentage of soybean land cover (22.5% [Nahunta]; 1.6% [Little River]). Agricultural land covers had varied nitrogen response times to changes in atmospheric deposition, particularly for soybean, hay and corn. The studied watersheds retained >80% of all nitrogen delivered by agriculture fertilization, biological fixation and atmospheric deposition.

  12. Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity.

    PubMed

    Miah, Mohammad Alam; Byeon, Se Eun; Ahmed, Md Selim; Yoon, Cheol-Hee; Ha, Sang-Jun; Bae, Yong-Soo

    2013-09-01

    Early growth response gene 2 (Egr2), which encodes a zinc finger transcription factor, is rapidly and transiently induced in various cell types independently of de novo protein synthesis. Although a role for Egr2 is well established in T-cell development, Egr2 expression and its biological function in dendritic cells (DCs) have not yet been described. Here, we demonstrate Egr2 expression during DC development, and its role in DC-mediated immune responses. Egr2 is expressed in the later stage of DC development from BM precursor cells. Even at steady state, Egr2 is highly expressed in mouse splenic DCs. Egr2-knockdown (Egr2-KD) DCs showed increased levels of major histocompatability complex (MHC) class I and II and co-stimulatory molecules, and enhanced antigen uptake and migratory capacities. Furthermore, Egr2-KD abolished SOCS1 expression and signal transducer and activator of transcription 5 (STAT5) activation during DC development, probably resulting in the enhancement of IL-12 expression and Th1 immunogenicity of a DC vaccine. DC-mediated cytotoxic T lymphocyte (CTL) activation and antitumor immunity were significantly enhanced by Egr2-KD, and impaired by Egr2 overexpression in antigen-pulsed DC vaccines. These data suggest that Egr2 acts as an intrinsic negative regulator of DC immunogenicity and can be an attractive molecular target for DC vaccine development.

  13. Sulfur Dioxide Emissions and Market Effects under the Clean Air Act Acid Rain Program.

    PubMed

    Zipper, Carl E; Gilroy, Leonard

    1998-09-01

    The Clean Air Act Amendments of 1990 (CAAA90) established a national program to control sulfur dioxide (SO2) emissions from electricity generation. CAAA90's market-based approach includes trading and banking of Soumissions allowances. We analyzed data describing electric utility SO2 emissions in 1995, the first year of the program's Phase I, and market effects over the 1990-1995 period. Fuel switching and flue-gas desulfurization were the dominant means used in 1995 by targeted generators to reduce emissions to 51% of 1990 levels. Flue-gas desulfur-ization costs, emissions allowance prices, low-sulfur coal prices, and average sulfur contents of coals shipped to electric utilities declined over the 1990-1995 period. Projections indicate that 13-15 million allowances will have been banked during the program's Phase I, which ends in 1999, a quantity expected to last through the first decade of the program's stricter Phase II controls. In 1995, both allowance prices and SO2 emissions were below pre-CAAA90 expectations. The reduction of SO2 emissions beyond pre-CAAA90 expectations, combined with lower-than-expected allowance prices and declining compliance costs, can be viewed as a success for market-based environmental controls.

  14. 78 FR 79729 - Integrated Mortgage Disclosures Under the Real Estate Settlement Procedures Act (Regulation X...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...Sections 1098 and 1100A of the Dodd-Frank Wall Street Reform and Consumer Protection Act (Dodd-Frank Act) direct the Bureau to publish rules and forms that combine certain disclosures that consumers receive in connection with applying for and closing on a mortgage loan under the Truth in Lending Act and the Real Estate Settlement Procedures Act. Consistent with this requirement, the Bureau is......

  15. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES... objective intent; (3) The manufacture of the HCT/P does not involve the combination of the cells or tissues... not have a systemic effect and is not dependent upon the metabolic activity of living cells for...

  16. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES... objective intent; (3) The manufacture of the HCT/P does not involve the combination of the cells or tissues... not have a systemic effect and is not dependent upon the metabolic activity of living cells for...

  17. Intron retention as a component of regulated gene expression programs.

    PubMed

    Jacob, Aishwarya G; Smith, Christopher W J

    2017-04-08

    Intron retention has long been an exemplar of regulated splicing with case studies of individual events serving as models that provided key mechanistic insights into the process of splicing control. In organisms such as plants and budding yeast, intron retention is well understood as a major mechanism of gene expression regulation. In contrast, in mammalian systems, the extent and functional significance of intron retention have, until recently, remained greatly underappreciated. Technical challenges to the global detection and quantitation of transcripts with retained introns have often led to intron retention being overlooked or dismissed as "noise". Now, however, with the wealth of information available from high-throughput deep sequencing, combined with focused computational and statistical analyses, we are able to distinguish clear intron retention patterns in various physiological and pathological contexts. Several recent studies have demonstrated intron retention as a central component of gene expression programs during normal development as well as in response to stress and disease. Furthermore, these studies revealed various ways in which intron retention regulates protein isoform production, RNA stability and translation efficiency, and rapid induction of expression via post-transcriptional splicing of retained introns. In this review, we highlight critical findings from these transcriptomic studies and discuss commonalties in the patterns prevalent in intron retention networks at the functional and regulatory levels.

  18. Developing a state wellhead protection program: a user's guide to assist state agencies under the Safe Drinking Water Act

    SciTech Connect

    Roy, S.

    1988-07-01

    The 1986 Amendments to the Safe Drinking Water Act established a new Wellhead Protection (WHP) Program to protect ground water that supplies drinking water wells from sources of contamination. Under Section 1428 of the Act, each State must prepare a WHP program and submit it to EPA by June 19, 1989. Although the law requires that every State WHP program must contain specific elements, EPA recognizes that States should be allowed flexibility to tailor program details to best suit their individual needs. The document provides an overview of the major program requirements, presents major messages that a State should consider while developing a WHP program, and presents case-study examples to illustrate how a State might address each element of its WHP program.

  19. 76 FR 72878 - Financial Crimes Enforcement Network; Amendment to the Bank Secrecy Act Regulations-Imposition of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... Act Regulations--Imposition of Special Measure Against the Islamic Republic of Iran as a Jurisdiction... of FinCEN, found that reasonable grounds exist for concluding that the Islamic Republic of Iran...CEN has determined that reasonable grounds exist for concluding that the Islamic Republic of Iran is...

  20. 78 FR 63408 - Petition To Amend Animal Welfare Act Regulations To Prohibit Public Contact With Big Cats, Bears...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... Animal Welfare Act Regulations To Prohibit Public Contact With Big Cats, Bears, and Nonhuman Primates... exceptions, from coming into direct or physical contact with big cats, bears, or nonhuman primates of any age... big cats, bears, and nonhuman primates and the separation of such animals from their dams before...

  1. 76 FR 39007 - Native American Graves Protection and Repatriation Act Regulations- Definition of “Indian Tribe”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... and Repatriation Act Regulations-- Definition of ``Indian Tribe'' AGENCY: Office of the Secretary... definition of ``Indian tribe,'' because it is inconsistent with the statutory definition of that term. DATES... definition of ``Indian tribe'' into NAGPRA verbatim from the Indian Self Determination and...

  2. 75 FR 29526 - Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... No: 2010-12622] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [131 FERC ] 61,161; Docket No. RM93-11-000] Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual Change in the Producer Price Index for Finished Goods May 19, 2010. The...

  3. 76 FR 28966 - Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual Change in the Producer Price Index for Finished Goods The...

  4. 77 FR 29997 - Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual Change in the Producer Price Index for Finished Goods The...

  5. 78 FR 30296 - Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual Change in the Producer Price Index for Finished Goods The...

  6. 78 FR 30739 - Amendments to the 2013 Escrows Final Rule under the Truth in Lending Act (Regulation Z)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...) and Homeownership Counseling Amendments to the Real Estate Settlement Procedures Act (Regulation X... Appraisals Final Rule), 78 FR 7215 (Jan. 31, 2013); Mortgage Servicing Rules Under the Real Estate Settlement...). \\13\\ 73 FR 44522 (July 30, 2008). IV. Section-by-Section Analysis Section 1026.35 Requirements...

  7. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  8. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false States designated under paragraph 5(c) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... Designating Establishments With Operations Which Would Clearly Endanger the Public Health; Disposition...

  9. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  10. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  11. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false States designated under paragraph 5(c) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... Designating Establishments With Operations Which Would Clearly Endanger the Public Health; Disposition...

  12. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  13. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false States designated under paragraph 5(c) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... Designating Establishments With Operations Which Would Clearly Endanger the Public Health; Disposition...

  14. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  15. Self-Regulation Empowerment Program: A School-Based Program to Enhance Self-Regulated and Self-Motivated Cycles of Student Learning

    ERIC Educational Resources Information Center

    Cleary, Timothy J.; Zimmerman, Barry J.

    2004-01-01

    This article describes a training program, Self-Regulation Empowerment Program (SREP), that school professionals can use to empower adolescent students to engage in more positive, self-motivating cycles of learning. It is a two-part approach whereby self-regulated learning coaches (SRC) (a) use microanalytic assessment procedures to assess…

  16. Employee Retirement Income Security Act of 1974: rules and regulations for administration and enforcement; claims procedure. Pension and Welfare Benefits Administration, Labor. Final regulation.

    PubMed

    2000-11-21

    This document contains a final regulation revising the minimum requirements for benefit claims procedures of employee benefit plans covered by Title I of the Employee Retirement Income Security Act of 1974 (ERISA or the Act). The regulation establishes new standards for the processing of claims under group health plans and plans providing disability benefits and further clarifies existing standards for all other employee benefit plans. The new standards are intended to ensure more timely benefit determinations, to improve access to information on which a benefit determination is made, and to assure that participants and beneficiaries will be afforded a full and fair review of denied claims. When effective, the regulation will affect participants and beneficiaries of employee benefit plans, employers who sponsor employee benefit plans, plan fiduciaries, and others who assist in the provision of plan benefits, such as third-party benefits administrators and health service providers or health maintenance organizations that provide benefits to participants and beneficiaries of employee benefit plans.

  17. 75 FR 77607 - Privacy Act of 1974; Proposed New System of Records; Veterinary Medicine Loan Repayment Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Office of the Secretary Privacy Act of 1974; Proposed New System of Records; Veterinary Medicine Loan... of Agriculture system of records notice titled, ``Veterinary Medicine Loan Repayment Program Records... subject line of the message. Fax: (202) 401-7752. Mail: Gary Sherman; National Program Leader,...

  18. An Evaluation of Public School Participation in Comprehensive Employment and Training Act (CETA) Youth Programs in Utah's Bear River District.

    ERIC Educational Resources Information Center

    Lindholm, Michael; Jones, Roger C.

    This study evaluated the effectiveness of school district participation in CETA (Comprehensive Employment and Training Act) youth programs in Box Elder and Cache Counties, Utah, as well as the overall effectiveness of CETA youth programs administered by the Bear River Association of Governments. For three years, the Bear River Association of…

  19. 78 FR 73195 - Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... HUMAN SERVICES Centers for Medicare & Medicaid Services Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching Program Match No. 1312 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer...

  20. 77 FR 39748 - Computer Matching and Privacy Protection Act of 1988; Report of Matching Program: RRB and State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ...] [FR Doc No: 2012-16384] RAILROAD RETIREMENT BOARD Computer Matching and Privacy Protection Act of 1988...: Notice of a renewal of an existing computer matching program due to expire on August 12, 2012. SUMMARY..., information obtained from state agencies in ongoing computer matching programs regarding individuals...

  1. 78 FR 47336 - Privacy Act of 1974; Computer Matching Program Between the Department of Housing and Urban...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... URBAN DEVELOPMENT Privacy Act of 1974; Computer Matching Program Between the Department of Housing and Urban Development (HUD) and the Department of Health and Human Services (HHS): Matching Tenant Data in... attained by HUD through the matching program. The most recent renewal of the current matching...

  2. 77 FR 38611 - Privacy Act of 1974; System of Records-Study of Promising Features of Teacher Preparation Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Privacy Act of 1974; System of Records--Study of Promising Features of Teacher Preparation Programs AGENCY... Teacher Preparation Programs'' (18-13-29). The National Center for Education Evaluation and Regional... Abt Associates to conduct a rigorous study of the effect on student learning of teachers who...

  3. 40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (I/M) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised...

  4. 40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (I/M) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised...

  5. The ACT College Outcome Measurement Project: A New Tool for Summative Evaluation of Nontraditional Postsecondary Education Programs?

    ERIC Educational Resources Information Center

    Ward, Eric F.; Pringle, Robert A.

    The American College Testing Program (ACT) developed tests as a result of the College Outcome Measures Project (COMP). These instruments were intended for evaluation of nontraditional and traditional postsecondary education programs. They measure skills rather than information. The study was designed to check on several aspects of use of the COMP…

  6. Youth Programs and the Job Training Partnership Act. Developing Competency Standards: A Guide for Private Industry Council Members.

    ERIC Educational Resources Information Center

    Strumpf, Lori

    This guide is intended to assist Private Industry Council (PIC) members in developing competency standards for youth programs receiving Job Training Partnership Act (JTPA) funds. Discussed first are the benefits of competency standards to PICs and service delivery areas (SDAs). The various components of program standards (types of skills, skill…

  7. Title I of the Higher Education Act of 1965: A Study of Program Compliance with Congressional Intent.

    ERIC Educational Resources Information Center

    Senecal, Robert Joseph

    The study examined the compliance of programs funded under Title I of the Higher Education Act of 1965 with Congressional intent, and explored the nature of the relationships between the measures of compliance and selected organizational characteristics of participating colleges and universities. Eighty-two programs, funded during the fiscal year…

  8. Metropolitan Housing Desegregation: The Case for an Affirmative Program under Title VI of the Civil Rights Act of 1964.

    ERIC Educational Resources Information Center

    Levin, Arthur, J.; Silard, John

    A 1966 document reviews a number of issues about housing segregation, which are related to Title IV of the Civil Rights Act of 1964. Discussed in five sections are the displacement impact of major Federal construction programs, Federal assistance to private housing, metropolitan housing desegregation, affirmative programs for desegregation, and…

  9. AIDS Drug Assistance Programs: managers confront uncertainty and need to adapt as the Affordable Care Act kicks in.

    PubMed

    Martin, Erika G; Meehan, Terence; Schackman, Bruce R

    2013-06-01

    With the Affordable Care Act set to expand insurance coverage to millions more Americans next year, existing discretionary health programs that receive federal support might find themselves competing for funds as the health reform law is fully implemented. To assess the implications the Affordable Care Act might have for discretionary health programs, we focused on state AIDS Drug Assistance Programs, which provide free medications to low-income HIV patients. We conducted semistructured interviews with program managers from twenty-two states. Many of the managers predicted that their programs will change focus to provide "wrap-around services," such as helping newly insured clients finance out-of-pocket expenses, including copayments, deductibles, and premiums. Although program managers acknowledged that they must adapt to a changing environment, many said that they were overwhelmed by the complexity of the Affordable Care Act, and some expressed fear that state AIDS Drug Assistance Programs would be eliminated entirely. To remain viable, such programs must identify and justify the need for services in the context of the Affordable Care Act and receive sufficient political support and funding.

  10. 76 FR 28461 - Program Year 2011 Allotments and Grants: Workforce Investment Act, Wagner-Peyser Act, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ....19 Illinois 43,545,632 36,086,031 (7,459,601) -17.13 Indiana 19,697,136 16,043,006 (3,654,130) -18.55...,104,108 (1,123,492) -18.04 South Carolina 23,089,893 19,186,456 (3,903,437) -16.91 South Dakota 1,000... Partnership Act (JTPA) section 202(a)(3) (as amended by section 701 of the Job Training Reform Amendments...

  11. The Medical Library Assistance Act: An Analysis of the NLM Extramural Programs, 1965-1970 *

    PubMed Central

    Cummings, Martin M.; Corning, Mary E.

    1971-01-01

    The imbalance between medical library resources and information needs of the health professional led to a reexamination of the mandate for the National Library of Medicine. Legislation known as the Medical Library Assistance Act (MLAA) was passed in 1965 which enabled the NLM to (1) initiate programs to assist the nation's medical libraries and (2) develop a medical library network with the establishment of regional medical libraries to link the NLM with local institutions. The National Library of Medicine, through the MLAA, has made available $40.8 million to the medical library community under a competitive grant and contract mechanism for the period July 1965—June 1970. A total of 604 projects has been executed in resources, research and development, training, construction, regional medical libraries, publications, and special scientific projects. An assessment is given of each of these programs and their impact on both the National Library of Medicine and individual medical libraries. In the aggregate, these programs have significantly improved library and information services to the professional health user. The principal limitation has been inadequate funding to accomplish the level of originally stated objectives. PMID:5146762

  12. Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.

    PubMed

    Liu, Huarui; Strauss, Tamara J; Potts, Malia B; Cameron, Scott

    2006-02-01

    Hox genes are crucial determinants of cell fates and of body morphology of animals; mutations affecting these genes result in abnormal patterns of programmed cell death. How Hox genes regulate programmed cell death is an important and poorly understood aspect of normal development. In the nematode C. elegans, the Hox gene mab-5 is required for the programmed cell deaths of two lineally related cells generated in the P11 and P12 lineages. We show here that in the P11 lineage, a complex between MAB-5 and the Pbx homolog CEH-20 directly regulates transcription of the BH3 domain gene egl-1 to initiate programmed cell death; in the P12 lineage, mab-5 and ceh-20 apparently act indirectly to initiate programmed cell death. Direct regulation of programmed cell death may be an evolutionarily ancient and conserved function of Hox genes.

  13. A Study of the Education Professions Development Act Training Programs for Higher Education Personnel, Volume III: The EPDA V-E Training Programs. Final Report.

    ERIC Educational Resources Information Center

    Boyle, E.; Carlson, K.

    Volume III of a study of the Education Professions Development Act (EPDA) training programs for higher education personnel presents the second of a three-faceted approach to assess current needs. This document reviews the task of profiling EPDA V-E training programs to produce a small-scale information system. Section one reviews the profiling…

  14. Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis.

    PubMed

    Bhatia, Neha; Bozorg, Behruz; Larsson, André; Ohno, Carolyn; Jönsson, Henrik; Heisler, Marcus G

    2016-12-05

    The periodic formation of plant organs such as leaves and flowers gives rise to intricate patterns that have fascinated biologists and mathematicians alike for hundreds of years [1]. The plant hormone auxin plays a central role in establishing these patterns by promoting organ formation at sites where it accumulates due to its polar, cell-to-cell transport [2-6]. Although experimental evidence as well as modeling suggest that feedback from auxin to its transport direction may help specify phyllotactic patterns [7-12], the nature of this feedback remains unclear [13]. Here we reveal that polarization of the auxin efflux carrier PIN-FORMED 1 (PIN1) is regulated by the auxin response transcription factor MONOPTEROS (MP) [14]. We find that in the shoot, cell polarity patterns follow MP expression, which in turn follows auxin distribution patterns. By perturbing MP activity both globally and locally, we show that localized MP activity is necessary for the generation of polarity convergence patterns and that localized MP expression is sufficient to instruct PIN1 polarity directions non-cell autonomously, toward MP-expressing cells. By expressing MP in the epidermis of mp mutants, we further show that although MP activity in a single-cell layer is sufficient to promote polarity convergence patterns, MP in sub-epidermal tissues helps anchor these polarity patterns to the underlying cells. Overall, our findings reveal a patterning module in plants that determines organ position by orienting transport of the hormone auxin toward cells with high levels of MP-mediated auxin signaling. We propose that this feedback process acts broadly to generate periodic plant architectures.

  15. Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells

    PubMed Central

    Yu, Jenn-Yah; Reynolds, Steven H.; Hatfield, Steve D.; Shcherbata, Halyna R.; Fischer, Karin A.; Ward, Ellen J.; Long, Dang; Ding, Ye; Ruohola-Baker, Hannele

    2009-01-01

    Summary It is important to understand the regulation of stem cell division because defects in this process can cause altered tissue homeostasis or cancer. The cyclin-dependent kinase inhibitor Dacapo (Dap), a p21/p27 homolog, acts downstream of the microRNA (miRNA) pathway to regulate the cell cycle in Drosophila melanogaster germline stem cells (GSCs). Tissue-extrinsic signals, including insulin, also regulate cell division of GSCs. We report that intrinsic and extrinsic regulators intersect in GSC division control; the Insulin receptor (InR) pathway regulates Dap levels through miRNAs, thereby controlling GSC division. Using GFP-dap 3′UTR sensors in vivo, we show that in GSCs the dap 3′UTR is responsive to Dicer-1, an RNA endonuclease III required for miRNA processing. Furthermore, the dap 3′UTR can be directly targeted by miR-7, miR-278 and miR-309 in luciferase assays. Consistent with this, miR-278 and miR-7 mutant GSCs are partially defective in GSC division and show abnormal cell cycle marker expression, respectively. These data suggest that the GSC cell cycle is regulated via the dap 3′UTR by multiple miRNAs. Furthermore, the GFP-dap 3′UTR sensors respond to InR but not to TGF-β signaling, suggesting that InR signaling utilizes Dap for GSC cell cycle regulation. We further demonstrate that the miRNA-based Dap regulation may act downstream of InR signaling; Dcr-1 and Dap are required for nutrition-dependent cell cycle regulation in GSCs and reduction of dap partially rescues the cell cycle defect of InR-deficient GSCs. These data suggest that miRNA- and Dap-based cell cycle regulation in GSCs can be controlled by InR signaling. PMID:19336466

  16. Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells.

    PubMed

    Yu, Jenn-Yah; Reynolds, Steven H; Hatfield, Steve D; Shcherbata, Halyna R; Fischer, Karin A; Ward, Ellen J; Long, Dang; Ding, Ye; Ruohola-Baker, Hannele

    2009-05-01

    It is important to understand the regulation of stem cell division because defects in this process can cause altered tissue homeostasis or cancer. The cyclin-dependent kinase inhibitor Dacapo (Dap), a p21/p27 homolog, acts downstream of the microRNA (miRNA) pathway to regulate the cell cycle in Drosophila melanogaster germline stem cells (GSCs). Tissue-extrinsic signals, including insulin, also regulate cell division of GSCs. We report that intrinsic and extrinsic regulators intersect in GSC division control; the Insulin receptor (InR) pathway regulates Dap levels through miRNAs, thereby controlling GSC division. Using GFP-dap 3'UTR sensors in vivo, we show that in GSCs the dap 3'UTR is responsive to Dicer-1, an RNA endonuclease III required for miRNA processing. Furthermore, the dap 3'UTR can be directly targeted by miR-7, miR-278 and miR-309 in luciferase assays. Consistent with this, miR-278 and miR-7 mutant GSCs are partially defective in GSC division and show abnormal cell cycle marker expression, respectively. These data suggest that the GSC cell cycle is regulated via the dap 3'UTR by multiple miRNAs. Furthermore, the GFP-dap 3'UTR sensors respond to InR but not to TGF-beta signaling, suggesting that InR signaling utilizes Dap for GSC cell cycle regulation. We further demonstrate that the miRNA-based Dap regulation may act downstream of InR signaling; Dcr-1 and Dap are required for nutrition-dependent cell cycle regulation in GSCs and reduction of dap partially rescues the cell cycle defect of InR-deficient GSCs. These data suggest that miRNA- and Dap-based cell cycle regulation in GSCs can be controlled by InR signaling.

  17. Mixed Waste Integrated Program: Demonstrating technologies to meet the requirements of the Federal Facility Compliance Act

    SciTech Connect

    Berry, J.B.

    1994-07-01

    Mixed waste is defined as ``waste contaminated with chemically hazardous [governed by the Resource Conservation and Recovery Act (RCRA)] and radioactive species [governed by US Department of energy (DOE) orders].`` The Mixed Waste Integrated Program (MWIP) is responding to the need for DOE mixed-waste treatment technologies tat meet these dual regulatory requirements. MWIP is developing emerging and innovative treatment technologies to determine process feasibility. Technology demonstrations of fixed-hearth plasma arc and vitrification systems will be used to determine whether these processes are superior to existing technologies in reducing risk, minimizing life-cycle cost, and improving process performance. MWIP also provides a forum for stakeholder and customer involvement in the technology development process.

  18. 75 FR 60263 - Federal Acquisition Regulation; Offering a Construction Requirement-8(a) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Federal Acquisition Regulation; Offering a Construction Requirement--8(a) Program AGENCIES: Department of... Regulations Council (Councils) are issuing a final rule amending the Federal Acquisition Regulation (FAR) to revise FAR subpart 19.8, Contracting with the Small Business Administration (The 8(a) Program),...

  19. 20 CFR 668.140 - What WIA regulations apply to the INA program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false What WIA regulations apply to the INA program? 668.140 Section 668.140 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Purposes and Policies § 668.140 What WIA regulations apply to the INA program? (a) The regulations found...

  20. 20 CFR 668.140 - What WIA regulations apply to the INA program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What WIA regulations apply to the INA program? 668.140 Section 668.140 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Policies § 668.140 What WIA regulations apply to the INA program? (a) The regulations found in this...