Science.gov

Sample records for act program regulation

  1. 76 FR 10527 - Regulatory Flexibility Act: Section 610 Review of National Organic Program Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... regulations implementing the National Organic Program (NOP) were published December 21, 2000 (65 FR 80548... FR 14827), its schedule to review certain regulations, including the NOP regulations, under criteria... Organic Program Regulations AGENCY: Agricultural Marketing Service, USDA. ACTION: Review and request...

  2. Guidance for applicants for state wellhead protection program assistance funds under the Safe Drinking Water Act. Appendix C. Wellhead Protection Program-applicable regulations

    SciTech Connect

    Not Available

    1987-06-01

    Appendix C is a companion document to the Guidance for Applicants for State Wellhead Protection Assistance Funds Under the Safe Drinking Water Act to explain EPA regulations applicable to the Wellhead Protection Program (WHP) and the assistance application form needed to request a program grant. These two documents are used to develop approvable assistance applications and to administer properly the funds awarded under the WHP program.

  3. The ACTS propagation program

    NASA Technical Reports Server (NTRS)

    Chakraborty, Dayamoy; Davarian, Faramaz

    1991-01-01

    The purpose of the Advanced Communications Technology Satellite (ACTS) is to demonstrate the feasibility of the Ka-band (20 and 30 GHz) spectrum for satellite communications, as well as to help maintain U.S. leadership in satellite communications. ACTS incorporates such innovative schemes as time division multiple access (TDMA), microwave and baseband switching, onboard regeneration, and adaptive application of coding during rain-fade conditions. The success or failure of the ACTS experiment will depend on how accurately the rain-fade statistics and fade dynamics can be predicted in order to derive an appropriate algorithm that will combat weather vagaries, specifically for links with small terminals, such as very small aperture terminals (VSAT's) where the power margin is a premium. This article describes the planning process and hardware development program that will comply with the recommendations of the ACTS propagation study groups.

  4. Biomass Program Recovery Act Factsheet

    SciTech Connect

    2010-03-01

    The Biomass Program has awarded about $718 million in American Recovery and Reinvestment Act (Recovery Act) funds. The projects the Program is supporting are intended to: Accelerate advanced biofuels research, development, and demonstration; Speed the deployment and commercialization of advanced biofuels and bioproducts; Further the U.S. bioindustry through market transformation and creating or saving a range of jobs.

  5. Brn3a and Islet1 act epistatically to regulate the gene expression program of sensory differentiation.

    PubMed

    Dykes, Iain M; Tempest, Lynne; Lee, Su-In; Turner, Eric E

    2011-07-01

    The combinatorial expression of transcription factors frequently marks cellular identity in the nervous system, yet how these factors interact to determine specific neuronal phenotypes is not well understood. Sensory neurons of the trigeminal ganglion (TG) and dorsal root ganglia (DRG) coexpress the homeodomain transcription factors Brn3a and Islet1, and past work has revealed partially overlapping programs of gene expression downstream of these factors. Here we examine sensory development in Brn3a/Islet1 double knock-out (DKO) mice. Sensory neurogenesis and the formation of the TG and DRG occur in DKO embryos, but the DRG are dorsally displaced, and the peripheral projections of the ganglia are markedly disturbed. Sensory neurons in DKO embryos show a profound loss of all early markers of sensory subtypes, including the Ntrk neurotrophin receptors, and the runt-family transcription factors Runx1 and Runx3. Examination of global gene expression in the E12.5 DRG of single and double mutant embryos shows that Brn3a and Islet1 are together required for nearly all aspects of sensory-specific gene expression, including several newly identified sensory markers. On a majority of targets, Brn3a and Islet1 exhibit negative epistasis, in which the effects of the individual knock-out alleles are less than additive in the DKO. Smaller subsets of targets exhibit positive epistasis, or are regulated exclusively by one factor. Brn3a/Islet1 double mutants also fail to developmentally repress neurogenic bHLH genes, and in vivo chromatin immunoprecipitation shows that Islet1 binds to a known Brn3a-regulated enhancer in the neurod4 gene, suggesting a mechanism of interaction between these genes. PMID:21734270

  6. 13 CFR 108.30 - Amendments to Act and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Amendments to Act and regulations. 108.30 Section 108.30 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Introduction to Part 108 § 108.30 Amendments to Act and regulations. A...

  7. 75 FR 37287 - Privacy Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... April 19, 2010 (75 FR 20298) for a public comment period to end on June 18, 2010. This rule amends the... CFR Part 200 RIN 0430-AA03 Privacy Act Regulations AGENCY: Recovery Accountability and Transparency... regulations implementing the Privacy Act of 1974 (Privacy Act), Public Law 93-579, 5 U.S.C. 552a. This...

  8. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... Federal Register, 73 FR 25594, May 7, 2008. The proposed amendments: (1) Waived all copying fees in..., 73 FR 54595, September 22, 2008, certain portions of BGFRS-37 (Electronic Applications) may be exempt... CFR Part 261a Privacy Act of 1974; Privacy Act Regulation AGENCY: Board of Governors of the...

  9. 75 FR 20298 - Privacy Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ...,'' pursuant to the Privacy Act, as amended (74 FR 60302, Nov. 20, 2009). The Board received no comments on...; ] RECOVERY ACCOUNTABILITY AND TRANSPARENCY BOARD 4 CFR Part 200 RIN 0430-AA03 Privacy Act Regulations AGENCY... and Transparency Board (Board) proposes to amend the Board's regulations implementing the Privacy...

  10. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400.457 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the...

  11. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400.457 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the...

  12. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400.457 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the...

  13. Handbook for the ACT Career Planning Program.

    ERIC Educational Resources Information Center

    American Coll. Testing Program, Iowa City, IA. Research and Development Div.

    Prepared by the Research and Development Division of the American College Testing (ACT) Program, this handbook contains information pertaining to the ACT Career Planning Program, a guidance program for students considering and entering post-high school career education programs. The primary instrument of the Career Planning Program is a Career…

  14. Title I, Higher Education Act Program Abstracts.

    ERIC Educational Resources Information Center

    Miller, Lorna M., Ed.

    The 1979 edition of the Title I, Higher Education Act Program Abstracts is presented. Directed toward state Title I, HEA administrators, the program abstracts are made available in order to encourage nationwide program replication of those tested and evaluated programs that have been conducted with Title I support by institutions of higher…

  15. NASA's Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia

    2003-01-01

    Marshall Space Flight Center (MSFC) was selected as the Principal Center for review of Clean Air Act (CAA) regulations. The CAA Principal Center is tasked to: 1) Provide centralized support to NASA/HDQ Code JE for the management and leadership of NASA's CAA regulation review process; 2) Identify potential impact from proposed CAA regulations to NASA program hardware and supporting facilities. The Shuttle Environmental Assurance Initiative, one of the responsibilities of the NASA CAA Working Group (WG), is described in part of this viewgraph presentation.

  16. The French Space Operation Act: Technical Regulations

    NASA Astrophysics Data System (ADS)

    Trinchero, J. P.; Lazare, B.

    2010-09-01

    The French Space Operation Act(FSOA) stipulates that a prime objective of the National technical regulations is to protect people, property, public health and the environment. Compliance with these technical regulations is mandatory as of 10 December 2010 for space operations by French space operators and for space operations from French territory. The space safety requirements and regulations governing procedures are based on national and international best practices and experience. A critical design review of the space system and procedures shall be carried out by the applicant, in order to verify compliance with the Technical Regulations. An independent technical assessment of the operation is delegated to CNES. The principles applied when drafting technical regulations are as follows: requirements must as far as possible establish the rules according to the objective to be obtained, rather than how it is to be achieved; requirements must give preference to international standards recognised as being the state of the art; requirements must take previous experience into account. Technical regulations are divided into three sections covering common requirements for the launch, control and return of a space object. A dedicated section will cover specific rules to be applied at the Guiana Space Centre. The main topics addressed by the technical regulations are: operator safety management system; study of risks to people, property, public health and the Earth’s environment; impact study on the outer space environment: space debris generated by the operation; planetary protection.

  17. The French Space Operations Act: Technical Regulations

    NASA Astrophysics Data System (ADS)

    Lazare, B.

    2013-12-01

    The French Space Operations Act (FSOA) [1] stipulates that one of the National Technical Regulations' prime objectives is to protect people, property, public health and the environment. Compliance with these Technical Regulations has been mandatory since 10 December, 2010 for space operations by French space operators and for space operations conducted on French territory. The space safety requirements and regulations governing procedures are based on national and international best practices and experience. A critical design review of the space system and procedures shall be carried out by applicant space operators, in order to verify compliance with the Technical Regulations. An independent technical assessment of the operation is delegated to CNES. The principles applied when drafting the Technical Regulations are as follows: requirements must, as far as possible, establish the rules according to the objective to be obtained, rather than how it is to be achieved; requirements must give preference to international standards recognised as being state of the art; requirements must take previous experience into account. The Technical Regulations are divided into three sections covering requirements common to the launch, control and return of a space object. A special section will cover specific rules to be applied at the Guiana Space Centre. The main topics addressed by the Technical Regulations are: operator safety management system; study of risks to people, property, public health and the Earth's environment; impact study on the outer space environment: space debris generated by the operation; planetary protection. The first version of the Technical Regulations [2], issued in March 2011, is dedicated to unmanned space systems.

  18. 78 FR 17176 - Federal Acquisition Regulation; Defense Base Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... Federal Acquisition Regulation; Defense Base Act AGENCIES: Department of Defense (DoD), General Services... Act as extended by the Defense Base Act. DATES: Interested parties should submit written comments to... Act as extended by the Defense Base Act. II. Discussion and Analysis The Defense Base Act of...

  19. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  20. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  1. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  2. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  3. 48 CFR 752.225-9 - Buy American Act-Trade Agreements Act-Balance of Payments Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Buy American Act-Trade Agreements Act-Balance of Payments Program. 752.225-9 Section 752.225-9 Federal Acquisition Regulations... CLAUSES Texts of Provisions and Clauses 752.225-9 Buy American Act—Trade Agreements Act—Balance...

  4. Environmental Guidance Program Reference Book: Marine Protection, Research, and Sanctuaries Act and Marine Mammal Protection Act. Revision 3

    SciTech Connect

    Not Available

    1988-01-31

    Two laws governing activities in the marine environment are considered in this Reference Book. The Marine Protection, Research, and Sanctuaries Act (MPRSA, P.L. 92-532) regulates ocean dumping of waste, provides for a research program on ocean dumping, and provides for the designation and regulation of marine sanctuaries. The Marine Mammal Protection Act (MMPA, P.L. 92-522) establishes a federal program to protect and manage marine mammals. The Fishery Conservation and Management Act (FCMA, P.L. 94-265) establishes a program to regulate marine fisheries resources and commercial marine fishermen. Because the Department of Energy (DOE) is not engaged in any activities that could be classified as fishing under FCMA, this Act and its regulations have no implications for the DOE; therefore, no further consideration of this Act is given within this Reference Book. The requirements of the MPRSA and the MMPA are discussed in terms of their implications for the DOE.

  5. 78 FR 18473 - Army Privacy Act Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... Register (71 FR 46052), the Department of the Army issued a final rule. This final rule corrects the... Department of the Army 32 CFR Part 505 Army Privacy Act Program AGENCY: Department of the Army, DoD. ACTION: Final rule. SUMMARY: The Department of the Army is amending its rule on notification of the...

  6. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  7. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject...

  8. 48 CFR 1480.102 - Buy Indian Act acquisition regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Buy Indian Act acquisition... INDIAN AFFAIRS SUPPLEMENT ACQUISITIONS UNDER THE BUY INDIAN ACT General 1480.102 Buy Indian Act... the Buy Indian Act. (b) This part is under the direct oversight and control of the Chief...

  9. Impact of new regulations on training programs

    SciTech Connect

    Copenhaver, E.D.

    1987-09-01

    Safety and health training is creating a complex and overlapping training environment for all DOE contractors. Requirements stem from a variety of Federal and state regulations such as those from the Resource Conservation and Recovery Act (RCRA), the Superfund Amendments Reauthorization Act (SARA, whose training requirements are carried out by OSHA), Hazard Communication Act, and several substance-specific laws. The training requirements of these regulations and the trends toward overlapping the requirements of several laws are reviewed. Environment, safety and health training is offered by the technical staff members in the relevant disciplines and by our multi-discipline training group at ORNL. We are increasing our coordination of all such efforts to develop a more orderly overall program. We identified a team to work toward coordination of required technical training in environment, safety, and health by listing key opportunities for technical training modules and cross-qualification. The strategy for developing the training matrix is outlined. 13 figs.

  10. Regulations Under the Americans With Disabilities Act; Genetic Information Nondiscrimination Act. Final rule.

    PubMed

    2016-05-17

    The Equal Employment Opportunity Commission (EEOC or Commission) is issuing its final rule to amend the regulations and interpretive guidance implementing Title I of the Americans with Disabilities Act (ADA) to provide guidance on the extent to which employers may use incentives to encourage employees to participate in wellness programs that ask them to respond to disability-related inquiries and/or undergo medical examinations. This rule applies to all wellness programs that include disability-related inquiries and/or medical examinations whether they are offered only to employees enrolled in an employer-sponsored group health plan, offered to all employees regardless of whether they are enrolled in such a plan, or offered as a benefit of employment by employers that do not sponsor a group health plan or group health insurance. Published elsewhere in this issue of the Federal Register, the EEOC also issued a final rule to amend the regulations implementing Title II of the Genetic Information Nondiscrimination Act (GINA) that addresses the extent to which employers may offer incentives for an employee's spouse to participate in a wellness program. PMID:27192736

  11. Regulations Under the Americans With Disabilities Act; Genetic Information Nondiscrimination Act. Final rule.

    PubMed

    2016-05-17

    The Equal Employment Opportunity Commission (EEOC or Commission) is issuing its final rule to amend the regulations and interpretive guidance implementing Title I of the Americans with Disabilities Act (ADA) to provide guidance on the extent to which employers may use incentives to encourage employees to participate in wellness programs that ask them to respond to disability-related inquiries and/or undergo medical examinations. This rule applies to all wellness programs that include disability-related inquiries and/or medical examinations whether they are offered only to employees enrolled in an employer-sponsored group health plan, offered to all employees regardless of whether they are enrolled in such a plan, or offered as a benefit of employment by employers that do not sponsor a group health plan or group health insurance. Published elsewhere in this issue of the Federal Register, the EEOC also issued a final rule to amend the regulations implementing Title II of the Genetic Information Nondiscrimination Act (GINA) that addresses the extent to which employers may offer incentives for an employee's spouse to participate in a wellness program.

  12. The Final Regulations to the Carl D. Perkins Vocational and Applied Technology Education Act of 1990.

    ERIC Educational Resources Information Center

    American Vocational Association, Alexandria, VA.

    This publication presents the final regulations to the Carl D. Perkins Vocational and Applied Technology Education Act of 1990. The first section is an analysis of the regulations. This analysis compares the proposed regulations to the final version and explains the differences between the two and the potential impact on program administration.…

  13. Safe drinking water act: Amendments, regulations and standards

    SciTech Connect

    Calabrese, E.J.; Gilbert, C.E.; Pastides, H.

    1989-01-01

    This book approaches the topic of safe drinking water by communicating how the EPA has responded to the mandates of Congress. Chapter 1 summarizes what is and will be involved in achieving safe drinking water. Chapter 2 describes the historical development of drinking water regulations. Chapter 3 summarizes the directives of the Safe Drinking Water Act Amendments of 1986. Chapters 4 through 9 discuss each phase of the regulatory program in turn. Specific problems associated with volatile organic chemicals, synthetic organics, inorganic chemicals, and microbiological contaminants are assessed in Chapter 4 and 5. The unique characteristics of radionuclides and their regulation are treated in Chapter 6. The disinfection process and its resultant disinfection by-products are presented in Chapter 7. The contaminant selection process and the additional contaminants to be regulated by 1989 and 1991 and in future years are discussed in Chapters 8 and 9. EPA's Office of Drinking Water's Health Advisory Program is explained in Chapter 10. The record of public water system compliance with the primary drinking water regulations is detailed in Chapter 11. Chapter 12 offers a nongovernmental perspective on the general quality of drinking water and how this is affected by a wide range of drinking water treatment technologies. Separate abstracts are processed for 5 chapters in this book for inclusion in the appropriate data bases.

  14. NASA Principal Center for Review of Clean Air Act Regulations

    NASA Technical Reports Server (NTRS)

    Clark-Ingram, Marceia; Munafo, Paul M. (Technical Monitor)

    2002-01-01

    The Clean Air Act (CAA) regulations have greatly impacted materials and processes utilized in the manufacture of aerospace hardware. Code JE/ NASA's Environmental Management Division at NASA Headquarters recognized the need for a formal, Agency-wide review process of CAA regulations. Marshall Space Flight Center (MSFC) was selected as the 'Principal Center for Review of Clean Air Act Regulations'. This presentation describes the centralized support provided by MSFC for the management and leadership of NASA's CAA regulation review process.

  15. 48 CFR 1480.102 - Buy Indian Act acquisition regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Buy Indian Act acquisition... INDIAN AFFAIRS SUPPLEMENT ACQUISITIONS UNDER THE BUY INDIAN ACT Subpart 1480.1 General 1480.102 Buy... in implementing the Buy Indian Act. (b) This part is under the direct oversight and control of...

  16. 13 CFR 107.30 - Amendments to Act and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Amendments to Act and regulations. 107.30 Section 107.30 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Introduction to Part 107 § 107.30 Amendments to Act and regulations. A Licensee shall...

  17. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American Act and...

  18. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2), use the following clause: Buy American Act and Balance...

  19. 32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false DoD Freedom of Information Act Program Components F Appendix F to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE... REGULATION Pt. 286, App. F Appendix F to Part 286—DoD Freedom of Information Act Program Components Office...

  20. 32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false DoD Freedom of Information Act Program Components F Appendix F to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE... REGULATION Pt. 286, App. F Appendix F to Part 286—DoD Freedom of Information Act Program Components Office...

  1. 32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false DoD Freedom of Information Act Program Components F Appendix F to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE... REGULATION Pt. 286, App. F Appendix F to Part 286—DoD Freedom of Information Act Program Components Office...

  2. 77 FR 75521 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ... 1, 2005. 70 FR 44256 (Aug. 2, 2005). As explained in the SUPPLEMENTARY INFORMATION section of these... Home Mortgage Disclosure Act (HMDA). 70 FR 12148 (Mar. 11, 2005). See 12 U.S.C. 2808; 12 CFR 203.2(e)(1... the other federal banking agencies in its CRA rule set forth at 12 CFR part 563e. 72 FR 13429 (Mar....

  3. 75 FR 36270 - Appraisal Subcommittee; Appraiser Regulation; Privacy Act Implementation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... INSTITUTIONS EXAMINATION COUNCIL 12 CFR Part 1102 Appraisal Subcommittee; Appraiser Regulation; Privacy Act... (October 1998). List of Subjects in 12 CFR Part 1102 Administrative practice and procedure, Banks, banking... of the Code of Federal Regulations is amended as follows: PART 1102--APPRAISER REGULATION Subpart...

  4. 78 FR 79283 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... CRA purposes by the OCC, Board, and FDIC on August 2, 2005, effective September 1, 2005. 70 FR 44256... Act (HMDA). 70 FR 12148 (Mar. 11, 2005). See 12 U.S.C. 2808; 12 CFR 203.2(e)(1). On March 22, 2007... other federal banking agencies in its CRA rule previously set forth at 12 CFR 563e. 72 FR 13429 (Mar....

  5. 76 FR 79529 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... adopted for CRA purposes by the OCC, Board, and FDIC on August 2, 2005, effective September 1, 2005. 70 FR... Disclosure Act (HMDA). 70 FR 12148 (Mar. 22, 2007). See 12 U.S.C. 2808; 12 CFR 203.2(e)(1). On March 22, 2007... federal banking agencies in its CRA rule set forth at 12 CFR 563e. 72 FR 13429. Pursuant to the...

  6. 75 FR 19241 - Financial Crimes Enforcement Network; Amendment to the Bank Secrecy Act Regulations; Defining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... for Mutual Funds, 67 FR 21117 (April 29, 2002); Customer Identification Programs for Mutual Funds, 68 FR 25131 (May 9, 2003); Amendment to the Bank Secrecy Act Regulations--Requirement That Mutual Funds Report Suspicious Activity, 71 FR 26213 (May 4, 2006); Anti-Money Laundering Programs; Special...

  7. 75 FR 79278 - Community Reinvestment Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... United States Department of Housing and Urban Development (HUD) under the Neighborhood Stabilization.../communitydevelopment/programs/neighborhoodspg/arrafactsheet.cfm . \\5\\ 74 FR 21377 (May 7, 2009); 73 FR 58330 (Oct. 6... October 19, 2010. See 75 FR 64322 (Oct. 19, 2010). Section 2301(c) of HERA, as amended, establishes...

  8. 77 FR 56824 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ACTION: Notice. Overview Information: Privacy Act of 1974; Computer Matching Program between the U.S. Department of Education and...

  9. 45 CFR 1336.30 - Eligibility under sections 804 and 805 of the Native American Programs Act of 1974.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Native American Programs Act of 1974. 1336.30 Section 1336.30 Public Welfare Regulations Relating to... THE ADMINISTRATION FOR NATIVE AMERICANS, NATIVE AMERICAN PROGRAMS NATIVE AMERICAN PROGRAMS Native American Projects § 1336.30 Eligibility under sections 804 and 805 of the Native American Programs Act...

  10. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  11. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  12. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  13. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  14. 40 CFR 80.1358 - What acts are prohibited under the gasoline benzene program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gasoline benzene program? 80.1358 Section 80.1358 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Violations and Penalties § 80.1358 What acts are prohibited under the gasoline benzene program? No person shall—...

  15. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  16. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  17. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall:...

  18. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  19. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  20. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  1. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  2. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall:...

  3. Health education assistance loan program: Public Health Service. Final regulations.

    PubMed

    1981-01-27

    This rule amends regulations for the Health Education Assistance Loan (HEAL) Program, authorized by the PHS Act, by: (1) removing the prohibition against receipt of a HEAL loan during the same school year in which a student receives loans from other federally provided or assisted loan programs under part B of Title IV of the Higher Education Act of 1965, (2) establishing a more flexible definition of academic year, (3) raising the maximum amount which may be borrowed, (4) changing the maximum interest rate, and (5) redesignating the location of the regulations in the code of Federal Regulations (CFR).

  4. 77 FR 75362 - Government in the Sunshine Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... From the Federal Register Online via the Government Publishing Office EQUAL EMPLOYMENT OPPORTUNITY COMMISSION 29 CFR Part 1612 Government in the Sunshine Act Regulations CFR Correction 0 In Title 29 of the Code of Federal Regulations, Parts 900 to 1899, revised as of July 1, 2012, on page 266, in Sec....

  5. ACTS Project and Propagation Program Update

    NASA Technical Reports Server (NTRS)

    Bauer, Robert

    1996-01-01

    Spacecraft operations continue to be nominal and the sixth eclipse season completed. Battery reconditioning to be re-evaluated before the fall eclipse. Other topics covered include: Inclined orbit; Experiments program; Reorganizations; Program timeline; and propagation program status.

  6. National Weatherization Assistance Program Characterization Describing the Recovery Act Period

    SciTech Connect

    Tonn, Bruce Edward; Rose, Erin M.; Hawkins, Beth A.

    2015-10-01

    This report characterizes the U.S. Department of Energy s Weatherization Assistance Program (WAP) during the American Recovery and Reinvestment Act of 2009 (Recovery Act) period. This research was one component of the Recovery Act evaluation of WAP. The report presents the results of surveys administered to Grantees (i.e., state weatherization offices) and Subgrantees (i.e., local weatherization agencies). The report also documents the ramp up and ramp down of weatherization production and direct employment during the Recovery Act period and other challenges faced by the Grantees and Subgrantees during this period. Program operations during the Recovery Act (Program Year 2010) are compared to operations during the year previous to the Recovery Act (Program Year 2008).

  7. 76 FR 47299 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  8. 78 FR 50146 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  9. 78 FR 21713 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  10. 75 FR 54966 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... AFFAIRS Privacy Act of 1974: Computer Matching Program AGENCY: Department of Veterans Affairs. ACTION: Notice of Computer Match Program. SUMMARY: Pursuant to 5 U.S.C. 552a, the Privacy Act of 1974, as amended... is hereby given that the Department of Veterans Affairs (VA) intends to conduct a computer...

  11. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Proceedings under this section will be in accordance with subpart L of 7 CFR part 1, “Procedures Related to... 7 Agriculture 6 2010-01-01 2010-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the...

  12. 7 CFR 400.457 - Program Fraud Civil Remedies Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Proceedings under this section will be in accordance with subpart L of 7 CFR part 1, “Procedures Related to... 7 Agriculture 6 2014-01-01 2014-01-01 false Program Fraud Civil Remedies Act. 400.457 Section 400...-Compliance § 400.457 Program Fraud Civil Remedies Act. (a) This section is in accordance with the...

  13. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of Payments Program Certificate. Buy American Act—Balance of Payments Program Certificate (DEC 2009)...

  14. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American and Balance...

  15. 48 CFR 252.225-7001 - Buy American Act and Balance of Payments Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Balance of Payments Program. 252.225-7001 Section 252.225-7001 Federal Acquisition Regulations System... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7001 Buy American Act and Balance of Payments Program. As prescribed in 225.1101(2)(i), use the following clause: Buy American and Balance...

  16. 77 FR 4498 - Rules and Regulations Under the Wool Products Labeling Act of 1939

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ...: Miscellaneous Rules: Final Rule, 63 FR 71582 (Dec. 29, 1998). \\7\\ Federal Trade Commission: Rules and... and Request for Public Comment on the Federal Trade Commission's Regulatory Review Program, 76 FR...; ] FEDERAL TRADE COMMISSION 16 CFR Part 300 Rules and Regulations Under the Wool Products Labeling Act...

  17. 75 FR 41370 - Regulations Implementing the Freedom of Information Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ... amended. 75 FR 22320, Apr. 28, 2010. Interested persons were afforded an opportunity to participate in the... HEALTH REVIEW COMMISSION 29 CFR Part 2201 Regulations Implementing the Freedom of Information Act AGENCY: Occupational Safety and Health Review Commission. ACTION: Final rule. SUMMARY: The Occupational Safety...

  18. 76 FR 59071 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... follows: Authority: 50 U.S.C. 401-442; 50 U.S.C. 403a-403v; 5 U.S.C. 552; Executive Order 13392, 70 FR... From the Federal Register Online via the Government Publishing Office CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1900 Freedom of Information Act Regulations AGENCY: Central Intelligence Agency....

  19. 76 FR 45403 - Bank Secrecy Act Regulations-Definitions and Other Regulations Relating to Prepaid Access

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... regulations. See 75 FR 65806 (October 26, 2010) (Transfer and Reorganization of Bank Secrecy Act Regulations... Relating to Money Services Businesses, 74 FR 22129 (May 12, 2009), was issued before the Chapter X Final...), (c). \\16\\ 75 FR 36589. B. Prior Regulation of Stored Value In 1999, when FinCEN issued its final...

  20. 43 CFR 17.302 - To what programs or activities do these regulations apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... regulations apply to each DOI recipient and to each program or activity operated by the recipient which receives Federal financial assistance provided by DOI. (b) The Act and these regulations do not apply...

  1. 76 FR 24564 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... INFORMATION: The notice of the matching program was last published on August 15, 2008 at 73 FR 48021. Members... Internal Revenue Service Privacy Act of 1974: Computer Matching Program AGENCY: Internal Revenue Service... Information to Federal, State and Local Agencies (DIFSLA) Computer Matching Program. DATES: Effective...

  2. 78 FR 15734 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR..., 76 FR 58525 (September 21, 2011). ] MA-DUA will provide the following to DHS/USCIS: MA-DUA records... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department...

  3. 78 FR 15732 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12... of Records Notice, 76 FR 58525 (September 21, 2011). CA-DHCS will provide the following to DHS/USCIS... SECURITY Office of the Secretary Privacy Act of 1974; Computer Matching Program AGENCY: Department...

  4. Medical loss ratio regulation under the Affordable Care Act.

    PubMed

    Harrington, Scott E

    2013-01-01

    The minimum medical loss ratio (MLR) regulations in the Affordable Care Act guarantee that a specific percentage of health insurance premiums is spent on medical care and specified activities to improve health care quality. This paper analyzes the regulations' potential unintended consequences and incentive effects, including: higher medical costs and premiums for some insurers; less innovation to align consumer, provider, and health plan incentives, less consumer choice and increased market concentration; and the risk that insurers will pay rebates if claim costs are lower than projected when premiums are established, despite the regulations' permitted "credibility adjustments." The paper discusses modifications and alternatives to the MLR regulations to help achieve their stated goals with less potential for adverse effects. PMID:23720876

  5. 77 FR 74347 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... Information Act (FOIA) (U.S.C. 552) in the Federal Register. See 77 FR 42673, July 20, 2012. CIGIE provided..., Regulatory Planning and Review, 58 FR 51735. This regulation has not been reviewed by the Office of.... Authority: Pub. L. 110-409, 122 Stat. 4302; 5 U.S.C. App; E.O. 12600, 52 FR 23781, 3 CFR, 1987 Comp., p....

  6. 76 FR 35963 - Disclosure of Information; Privacy Act Regulations; Notice and Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... CORPORATION 12 CFR Parts 309 and 310 RIN 3064-AD83 Disclosure of Information; Privacy Act Regulations; Notice... for comments. SUMMARY: The Dodd-Frank Wall Street Reform and Consumer Protection Act (Act), abolished... Freedom of Information Act (FOIA) and Privacy Act (PA) regulations will not be enforced by the FDIC...

  7. 75 FR 33838 - National Environmental Policy Act; Scientific Balloon Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... Space Flight Center's Wallops Flight Facility, Wallops Island, VA 23337. Comments also may be submitted... Program Manager, NASA Goddard Space Flight Center's Wallops Flight Facility; telephone 757-824-2319; or... SPACE ADMINISTRATION National Environmental Policy Act; Scientific Balloon Program AGENCY:...

  8. 75 FR 17788 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ...) Guidelines on the Conduct of Matching Programs (54 FR 25818 published June 19, 1989), and OMB Circular No. A... file when required (71 FR 1796, January 11, 2006). OPM will provide SSA with an electronic finder file... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management....

  9. 75 FR 31819 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ...) Guidelines on the Conduct of Matching Programs (54 FR 25818 published June 19, 1989), and OMB Circular No. A...'' microfilm file when required (71 FR 1796, January 11, 2006). OPM will provide SSA with an electronic finder... MANAGEMENT Privacy Act of 1974; Computer Matching Program AGENCY: Office of Personnel Management....

  10. 76 FR 50198 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... on June 19, 1989 (54 FR 25818), and OMB Circular No. A-130, Transmittal Memorandum 4, Management of... FR 35342, June 29, 2006). 3. Authority for Conducting the Matching Program ED is authorized to... Privacy Act of 1974; Computer Matching Program AGENCY: Office of the Inspector General, U.S. Department...

  11. 77 FR 38610 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... FR 25818, June 19, 1989); and OMB Circular A-130: 1. Names of Participating Agencies The Department... Privacy Act of 1974; Computer Matching Program AGENCY: Department of Education. ACTION: Notice--Computer... document provides notice of the continuation of the computer matching program between the Departments...

  12. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of... Act—Balance of Payments Program Certificate (DEC 2009) (a) Definitions. “Commercially available...

  13. 59 FR- Food Stamp Program: Certification Provisions of the Mickey Leland Childhood Hunger Relief Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-08-30

    ... Parents Participating in Drug or Alcohol Treatment Programs Under section 3(i) of the Food Stamp Act, food... children living with residents of alcohol or drug treatment centers are not eligible if the center provides... regulation, there have been changes in some drug and alcohol treatment centers' policy regarding addicts...

  14. A Parallel Program Analysis Framework for the ACTS Toolkit

    SciTech Connect

    Allen D. Malony

    2002-06-21

    OAK 270 - The final report summarizes the technical progress achieved during the project. A Parallel Program Analysis Framework for the acts toolkit, referred to as the TAU project. Described are the results in four work areas: (1) creation of a performance system for integrated instrumentation, measurement, analysis and visualization. (2) development of a performance measurement system for parallel profiling and tracing (3) development of an advanced program analysis system to enable creation of source-based performance and programing tools (4) development of parallel program interaction technology for accessing, performance information and application data during execution.

  15. 7 CFR 800.7 - Information about the Service, Act, and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information about the Service, Act, and regulations... AGRICULTURE GENERAL REGULATIONS Administration § 800.7 Information about the Service, Act, and regulations. Information about the Grain Inspection, Packers and Stockyards Administration, Service, Act,...

  16. 78 FR 38724 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... eligible for benefits under the Temporary Assistance for Needy Families (TANF) program and Supplemental... Matching and Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12, 2000). Participating Agencies: The Department of Homeland...

  17. 78 FR 15730 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Provisions of Public Law 100-503, the Computer Matching and Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12, 2000). Participating... Systematic Alien Verification for Entitlements Program System of Records Notice, 76 FR 58525 (September...

  18. Adaptive Equilibrium Regulation: A Balancing Act in Two Timescales

    PubMed Central

    Boker, Steven M.

    2015-01-01

    An equilibrium involves a balancing of forces. Just as one maintains upright posture in standing or walking, many self-regulatory and interpersonal behaviors can be framed as a balancing act between an ever changing environment and within-person processes. The emerging balance between person and environment, the equilibria, are dynamic and adaptive in response to development and learning. A distinction is made between equilibrium achieved solely due to a short timescale balancing of forces and a longer timescale preferred equilibrium which we define as a state towards which the system slowly adapts. Together, these are developed into a framework that this article calls Adaptive Equilibrium Regulation (ÆR), which separates a regulatory process into two timescales: a faster regulation that automatically balances forces and a slower timescale adaptation process that reconfigures the fast regulation so as to move the system towards its preferred equilibrium when an environmental force persists over the longer timescale. This way of thinking leads to novel models for the interplay between multiple timescales of behavior, learning, and development. PMID:27066197

  19. 78 FR 23885 - Federal Seed Act Program; Request for Extension and Revision of a Currently Approved Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... Agricultural Marketing Service Federal Seed Act Program; Request for Extension and Revision of a Currently... collection 7 CFR part 201 for Federal Seed Act Labeling and Enforcement. DATES: Comments on this document... submitted online at www.regulations.gov or sent to Fawad S. Shah, Director, Seed Regulatory and...

  20. 77 FR 43081 - Federal Acquisition Regulation; Information Collection; Buy American Act-Free Trade Agreements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... Regulation; Information Collection; Buy American Act--Free Trade Agreements--Israeli Trade Act Certificate... previously approved information collection requirement concerning the Buy American Act--Free Trade Agreements..., Buy American Act--Free Trade Agreements--Israeli Trade Act Certificate, by any of the...

  1. 75 FR 32480 - Funding Opportunity: Affordable Care Act Medicare Beneficiary Outreach and Assistance Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ... HUMAN SERVICES Administration on Aging Funding Opportunity: Affordable Care Act Medicare Beneficiary...: Availability of funding opportunity announcement. Funding Opportunity Title/Program Name: Affordable Care Act... Protection and Affordable Care Act of 2010 (Affordable Care Act). Catalog of Federal Domestic...

  2. Health Careers Opportunity Program (HCOP). Section 787 (Public Health Service Act). Program Guide.

    ERIC Educational Resources Information Center

    Department of Health and Human Services, Washington, DC.

    This document summarizes the requirements and guidelines for the Health Careers Opportunity Program (HCOP). This program is authorized by Section 787 of the Public Health Service Act to make grants to and contracts with postsecondary institutions to carry out programs which assist individuals from disadvantaged backgrounds to enter and graduate…

  3. Coastal Zone Management Act and related legislation: Revision 3. Environmental Guidance Program Reference Book

    SciTech Connect

    Not Available

    1993-10-15

    In recognition of the increasing pressures upon the nation`s coastal resources, Congress enacted the Coastal Zone Management Act in 1972. Its purpose is to encourage states to preserve, protect, develop, and, where possible, restore or enhance such valuable natural resources as wetlands, floodplains, estuaries, beaches, dunes, barrier islands, and coral reefs, as well as the fish and wildlife utilizing those habitats. A unique feature of the Act is that participation by states is voluntary. One key provision for encouraging states to participate is the availability of federal financial assistance to any coastal state or territory, including those on the Great Lakes, which is willing to develop and implement a comprehensive coastal management program. Additionally, the Coastal Barrier Resources Act (CBRA) was passed in 1983. This report contains the legislative history and statues associated with each Act. Regulations for implementation and other guidance are included.

  4. Regulation of toxic pollutants under the Clean Water Act: EPA's ten-year rulemaking nears completion

    SciTech Connect

    Wyche, B.W.

    1983-01-01

    Whether it's footdragging, or compliance is impossible, the Environmental Protection Agency (EPA) usually fails to meet its deadlines for issuing regulations. The best-known case is probably EPA's 10-year struggle to establish regulatory controls on toxic pollutants under the Clean Water Act. The developmental process is reviewed from the initial statutory framework (enacted in 1948) and the effluent limitations amendments (legislated in 1972), through its litigation history, to an analysis of the federal district court's three substantive opinions delivered during 1982. The author considers the possibility of legislative intervention because deadlines for compliance have been issued but the regulations have not. He concludes that without Toxics Consent Decree litigation, the toxic pollutant control program might have become a reality. EPA's toxic pollutant control regulations as of April 1, 1983, are tabulated. 129 references, 4 tables.

  5. 7 CFR 868.10 - Information about the Service, Act, and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information about the Service, Act, and regulations... § 868.10 Information about the Service, Act, and regulations. Information about the Service, Act... INSPECTION, PACKERS AND STOCKYARD ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT...

  6. 77 FR 57199 - 2012 Real Estate Settlement Procedures Act (Regulation X) Mortgage Servicing Proposal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ...The Bureau of Consumer Financial Protection (the Bureau) is proposing to amend Regulation X, which implements the Real Estate Settlement Procedures Act of 1974 (RESPA) and the official interpretation of the regulation. The proposed amendments implement the Dodd-Frank Wall Street Reform and Consumer Protection Act (Dodd-Frank Act) provisions regarding mortgage loan servicing. Specifically, this......

  7. Weatherization and Intergovernmental Program - The State Energy Program and the American Recovery and Reinvestment Act

    SciTech Connect

    2010-06-01

    To help the nation weather the ongoing economic downturn and meet key energy goals, the State Energy Program (SEP) will invest $3.1 billion from the American Recovery and Reinvestment Act of 2009 (Recovery Act) for additional grants. These grants do not require matching state funds.

  8. 76 FR 21741 - Twenty-First Century Communications and Video Programming Accessibility Act; Announcement of Town...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... COMMISSION Twenty-First Century Communications and Video Programming Accessibility Act; Announcement of Town... Programming Accessibility Act (the Act or CVAA) hosted by the California State University at Northridge (CSUN... and video programming changes required by the Act. DATES: The Town Hall meeting was held on...

  9. 21 CFR 16.24 - Regulatory hearing required by the act or a regulation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... regulation. 16.24 Section 16.24 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....24 Regulatory hearing required by the act or a regulation. (a) A regulatory hearing required by the act or a regulation under § 16.1(b) will be initiated in the same manner as other regulatory...

  10. 21 CFR 16.24 - Regulatory hearing required by the act or a regulation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... regulation. 16.24 Section 16.24 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN....24 Regulatory hearing required by the act or a regulation. (a) A regulatory hearing required by the act or a regulation under § 16.1(b) will be initiated in the same manner as other regulatory...

  11. 75 FR 58387 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One-Time... an extension of a currently approved information collection requirement concerning the American Recovery and Reinvestment Act-Reporting Requirements--One Time- Reporting, Compensation...

  12. 75 FR 58388 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--Quarterly... an extension of a currently approved information collection requirement concerning the American Recovery and Reinvestment Act--Quarterly Reporting for Prime Contractors. Public comments are...

  13. 42 CFR 4.1 - Programs to which these regulations apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... functions are performed by the Library directly for the benefit of the general public and health-sciences... Information Act or the Privacy Act of 1974 (5 U.S.C. 552, 552a). These matters are covered in 45 CFR parts 5... PROVISIONS NATIONAL LIBRARY OF MEDICINE § 4.1 Programs to which these regulations apply. (a) The...

  14. 42 CFR 4.1 - Programs to which these regulations apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... functions are performed by the Library directly for the benefit of the general public and health-sciences... Information Act or the Privacy Act of 1974 (5 U.S.C. 552, 552a). These matters are covered in 45 CFR parts 5... PROVISIONS NATIONAL LIBRARY OF MEDICINE § 4.1 Programs to which these regulations apply. (a) The...

  15. 42 CFR 4.1 - Programs to which these regulations apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... functions are performed by the Library directly for the benefit of the general public and health-sciences... Information Act or the Privacy Act of 1974 (5 U.S.C. 552, 552a). These matters are covered in 45 CFR parts 5... PROVISIONS NATIONAL LIBRARY OF MEDICINE § 4.1 Programs to which these regulations apply. (a) The...

  16. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false EPA review of State Clean Air Act... FEDERAL ASSISTANCE TRIBAL CLEAN AIR ACT AUTHORITY Tribal Authority § 49.10 EPA review of State Clean Air Act programs. A State Clean Air Act program submittal shall not be disapproved because of failure...

  17. Methods and Challenges Related to Implementing the New National School Lunch Program Regulations in Indiana

    ERIC Educational Resources Information Center

    Thiagarajah, Krisha; Getty, Victoria M.; Johnson, Hattie L.; Case, Megan; Herr, Susan J.

    2015-01-01

    Purpose/Objectives: The Healthy, Hunger-Free Kids Act of 2010 resulted in updated National School Lunch Program (NSLP) regulations from the U.S. Department of Agriculture. The purpose of this research was to investigate the approaches used by school foodservice managers and directors in Indiana in complying with the new regulations and to identify…

  18. 77 FR 12913 - Federal Acquisition Regulation; Women-Owned Small Business (WOSB) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... larger, more successful businesses. Response: Under the Small Business Jobs Act of 2010, Public Law 111... Small Business (WOSB) Program AGENCIES: Department of Defense (DoD), General Services Administration... Regulation (FAR) to implement the Small Business Administration's regulations establishing the...

  19. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false EPA review of State Clean Air Act programs. 49.10 Section 49.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  20. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false EPA review of State Clean Air Act programs. 49.10 Section 49.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  1. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false EPA review of State Clean Air Act programs. 49.10 Section 49.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  2. 40 CFR 49.10 - EPA review of State Clean Air Act programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false EPA review of State Clean Air Act programs. 49.10 Section 49.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... of State Clean Air Act programs. A State Clean Air Act program submittal shall not be...

  3. 78 FR 20291 - Fisheries of the United States; Billfish Conservation Act of 2012 Implementing Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    .... SUPPLEMENTARY INFORMATION: Background The Billfish Conservation Act of 2012 (BCA), Public Law 112-183, 16 U.S.C... States; Billfish Conservation Act of 2012 Implementing Regulations AGENCY: National Marine Fisheries... the implementation of the Billfish Conservation Act of 2012. DATES: Written comments regarding...

  4. 76 FR 24027 - Federal Acquisition Regulation; Information Collection; Buy American Act Certificate

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... Regulation; Information Collection; Buy American Act Certificate AGENCY: Department of Defense (DOD), General... previously approved information collection requirement concerning the Buy American Act certificate. Public...-mail cecelia.davis@gsa.gov . SUPPLEMENTARY INFORMATION: A. Purpose The Buy American Act requires...

  5. 75 FR 14547 - Tribal Consultation on Draft Buy Indian Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of Indian Affairs 48 CFR Chapter 14 RIN 1076-AE95 Tribal Consultation on Draft Buy Indian Act... comments concerning draft regulations to implement the Buy Indian Act. See the SUPPLEMENTARY INFORMATION... implementation of the Buy Indian Act, 25 U.S.C. 47, which provides authority to set aside procurement...

  6. 78 FR 70515 - Petition To Promulgate Standards for Bears Under the Animal Welfare Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... Standards for Bears Under the Animal Welfare Act Regulations AGENCY: Animal and Plant Health Inspection... Health Inspection Service has received a petition requesting that we amend the Animal Welfare Act..., Riverdale, MD 20737-1234; (301) 851-3751. SUPPLEMENTARY INFORMATION: Background The Animal Welfare Act...

  7. 76 FR 68690 - Rules and Regulations Under the Textile Fiber Products Identification Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... Wool Products Labeling Act, and the Fur Products Labeling Act: Final Rule, 63 FR 7508 (Feb. 13, 1998). \\2\\ Federal Trade Commission: Miscellaneous Rules: Final Rule, 63 FR 71582 (Dec. 29, 1998). \\3... and Regulations Under the Wool Products Labeling Act of 1939, Final Rule, 65 FR 75154 (Dec. 1,...

  8. 78 FR 29263 - Rules andRegulations Under the Textile Fiber Products Identification Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... Under the Textile Fiber Products Identification Act, 76 FR 68690 (Nov. 7, 2011). This Notice of Proposed...--Rules and Regulations Under the Textile Fiber Products Identification Act, 24 FR 4480, 4485 (June 2... Rulemaking, 50 FR 15100 at 15101 (Apr. 15, 1985). This Notice compared the Customs regulations in 19 CFR...

  9. 78 FR 41835 - Inflation Adjustments to the Price-Anderson Act Financial Protection Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... made the initial changes to the Price-Anderson Act amounts on October 27, 2005 (70 FR 61885), and the... Federal Regulations is sold by the Superintendent of Documents. #0;Prices of new books are listed in the... 3150-AJ25 Inflation Adjustments to the Price-Anderson Act Financial Protection Regulations...

  10. 5 CFR 293.202 - Records subject to Office or agency Privacy Act regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Privacy Act regulations. 293.202 Section 293.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... Records subject to Office or agency Privacy Act regulations. When the Office of Personnel Management publishes in the Federal Register a notice of system of records for personnel records which are...

  11. FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression.

    PubMed

    Zhao, J C; Fong, K-W; Jin, H-J; Yang, Y A; Kim, J; Yu, J

    2016-08-18

    Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2 and AR crosstalk and regulate hormone-dependent gene expression in prostate cancer cells. Chromatin immunoprecipitation sequencing analysis revealed that FOXA1 reprograms both AR and GATA2 cistrome by preferably recruiting them to FKHD-containing genomic sites. By contrast, GATA2 is unable to shift AR or FOXA1 to GATA motifs. Rather, GATA2 co-occupancy enhances AR and FOXA1 binding to nearby ARE and FKHD sites, respectively. Similarly, AR increases, but not reprograms, GATA2 and FOXA1 cistromes. Concordantly, GATA2 and AR strongly enhance the transcriptional program of each other, whereas FOXA1 regulates GATA2- and AR-mediated gene expression in a context-dependent manner due to its reprogramming effects. Taken together, our data delineated for the first time the distinct mechanisms by which GATA2 and FOXA1 regulate AR cistrome and suggest that FOXA1 acts upstream of GATA2 and AR in determining hormone-dependent gene expression in prostate cancer.

  12. Overview of the regulation of hazardous chemicals: SDWA (Safe Drinking Water Act), RCRA (Resource Conservation and Recovery Act), and CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act)

    SciTech Connect

    Baes, C.F. III

    1989-01-01

    The regulation of nonradioactive hazardous chemicals is carried out under a number of federal environmental laws that regulate either hazardous products, substances, or wastes. Because each law is intended to provide protection from different classes of substances (e.g., wastes vs products) or protect different media (e.g., air, water, land), the standards and levels of protection for different hazardous chemicals may be different. Nevertheless, one agency -- the Environmental Protection Agency (EPA) -- has primary responsibility for both promulgating regulations mandated by Congress under the various statutes and enforcement of the regulations. One overriding principal underlies the maze of complex regulations that govern the transport, treatment, storage, and disposal of hazardous substances: protect human health and the environment. It is beyond the scope of this talk to comprehensively examine all of the regulations and standards that govern the management of hazardous chemicals. Instead this discussion will focus on three statutes, the Safe Drinking Water Act (SDWA), the Resource Conservation and Recovery Act (RCRA), and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), that together provide a basis for a basic understanding of the approach that the EPA takes to regulating hazardous chemicals.

  13. 77 FR 57043 - Regulations Under the Fur Products Labeling Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... Labeling Act (``TFLA''), and, on its own initiative, deleting unnecessary requirements. \\1\\ 76 FR 13550..., most recently in 1967.\\17\\ \\16\\ 15 U.S.C. 69e(b). \\17\\ 32 FR 6023 (Apr. 15, 1967). C. TFLA In 2010....ftc.gov/opa/2011/07/regreview.shtm . \\24\\ 76 FR 13550. \\25\\ The comments, along with a transcript...

  14. 77 FR 50390 - Equal Credit Opportunity Act (Regulation B)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ..., such as account numbers or social security numbers, should not be included. Comments will not be edited... from the Bureau's rulemaking authority by section 1029 of the Dodd-Frank Act). 76 FR 79442 (Dec. 21...-reference to the definition of ``dwelling'' that, as discussed below, is proposed to be moved to Sec....

  15. 75 FR 22320 - Regulations Implementing the Freedom of Information Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... From the Federal Register Online via the Government Publishing Office OCCUPATIONAL SAFETY AND... Government Act), as well as changes in OSHRC's own policies and procedures. DATES: Submit comments on or before May 28, 2010. ADDRESSES: OSHRC encourages electronic submission of comments. You may...

  16. 77 FR 66539 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... electronic records and automated searches along with paper records and manual searches. In addition, FMCS's... twenty cents per page, while document search and review charges will increase to $4.00 per each quarter... revisions read as follows: Sec. 1401.36 Freedom of Information Act fee schedules. (a) * * * (2) Search...

  17. 78 FR 50351 - Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... without charge. These Direct Costs shall include the cost of operating a central processing unit for that... processing Requests for Information under the Freedom of Information Act (FOIA). The revisions reorganize the... reached before the NCPC charges members of the public a processing fee for information. DATES:...

  18. 78 FR 32595 - Revision of Freedom of Information Act Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ..., entitled ``Freedom of Information Act'' (74 FR 4683, January 26, 2009) and ``Transparency and Openness'' (74 FR 4685, January 26, 2009), which encourage federal agencies to apply a presumption of disclosure... published by the Department of Justice (DOJ) on March 21, 2011 (76 FR 15236). DOJ intended for these...

  19. The Equal Access Act: Policy and Regulations for Implementation.

    ERIC Educational Resources Information Center

    Jones, H. Lawrence; Martin, James

    The Equal Access Act of 1984 was drafted to implement access for religious clubs to public secondary schools, but with constitutionally protected safeguards to preclude entanglement of church and state. A number of challenges were made on the constitutional grounds of excessive entanglement of church and state, as well as what the definition of…

  20. 76 FR 15841 - General Rules and Regulations, Securities Act of 1933

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... COMMISSION 17 CFR Part 230 General Rules and Regulations, Securities Act of 1933 CFR Correction In Title 17 of the Code of Federal Regulations, Parts 200 to 239, revised as of April 1, 2010, on page 686, in.... 230.501 Definitions and terms used in Regulation D. * * * * * (e) * * * NOTE: The issuer must...

  1. 76 FR 9213 - Small Business Jobs Act: 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... RIN 3245-AG17 Small Business Jobs Act: 504 Loan Program Debt Refinancing AGENCY: U.S. Small Business... section 1122 of the Small Business Jobs Act of 2010 (Jobs Act), which authorizes projects approved for... section 1122 of the Jobs Act. DATES: Effective Date: This rule is effective February 17, 2011....

  2. 76 FR 18375 - Small Business Jobs Act: Eligible Loans for 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... ADMINISTRATION 13 CFR Part 120 Small Business Jobs Act: Eligible Loans for 504 Loan Program Debt Refinancing... Small Business Jobs Act. DATES: Effective Date: This document is effective April 4, 2011. FOR FURTHER... the Small Business Jobs Act (Jobs Act), Public Law 111-240, 124 Stat. 2504, only loans that...

  3. Clean Water Act (section 319): An evaluation of program implementation in region 10

    SciTech Connect

    Barfeld, E.

    1992-09-01

    Nonpoint source pollution, long overlooked in federal water pollution regulation, has now become a centerpiece of pollution control efforts. Congress added Section 319 -- the nonpoint source management programs section -- to the Clean Water Act in the 1987 Amendments to demonstrate federal commitment to nonpoint source control activities. Section 319(h) grant money, provided by EPA to individual states, forms an integral part of the federal nonpoint source program. EPA national and regional guidance give direction to the Section 319(h) grant program. As an evolving federal program Section 319 must carve out a niche for itself in relation to ongoing statewide nonpoint source control efforts. This paper provides an analysis of the Section 319 program and the effectiveness of Section 319(h)-funded projects in protecting water quality in Region 10 states, which include Washington, Oregon, Idaho, and Alaska. The report identifies characteristics of successful Section 319 projects, reviews selected Section 319 projects, highlights several important issues surrounding the Section 319 program, and makes recommendations for program improvement.

  4. ACT-CCREC Core Research Program: Study Questions and Design. ACT Working Paper Series. WP-2015-01

    ERIC Educational Resources Information Center

    Cruce, Ty M.

    2015-01-01

    This report provides a non-technical overview of the guiding research questions and research design for the ACT-led core research program conducted on behalf of the GEAR UP College and Career Readiness Evaluation Consortium (CCREC). The core research program is a longitudinal study of the effectiveness of 14 GEAR UP state grants on the academic…

  5. Atomic Energy Act and Related Legislation. Environmental Guidance Program Reference Book: Revision 6

    SciTech Connect

    Not Available

    1992-09-01

    This report presents information related to the Atomic Energy Act and related legislation. Sections are presented pertaining to legislative history and statutes, implementing regulations, and updates.

  6. 78 FR 43261 - Transportation Infrastructure Financing and Innovation Act (TIFIA) Program; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... Office of the Secretary of Transportation Transportation Infrastructure Financing and Innovation Act... for the Transportation Infrastructure Financing and Innovation Act (TIFIA) program to pay the subsidy....gov . SUPPLEMENTARY INFORMATION: Title: Transportation Infrastructure Financing and Innovation...

  7. 20 CFR 669.620 - How do the MSFW youth program regulations apply to the NFJP program authorized under WIA section...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false How do the MSFW youth program regulations... UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT The MSFW Youth Program § 669.620 How do the MSFW youth... only to the administration of grants for MSFW youth programs funded under WIA section...

  8. 20 CFR 669.620 - How do the MSFW youth program regulations apply to the NFJP program authorized under WIA section...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false How do the MSFW youth program regulations... UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT The MSFW Youth Program § 669.620 How do the MSFW youth... only to the administration of grants for MSFW youth programs funded under WIA section...

  9. 20 CFR 669.620 - How do the MSFW youth program regulations apply to the NFJP program authorized under WIA section...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false How do the MSFW youth program regulations... UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT The MSFW Youth Program § 669.620 How do the MSFW youth... only to the administration of grants for MSFW youth programs funded under WIA section...

  10. 20 CFR 669.620 - How do the MSFW youth program regulations apply to the NFJP program authorized under WIA section...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false How do the MSFW youth program regulations... EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR NATIONAL FARMWORKER JOBS PROGRAM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT The MSFW Youth Program § 669.620 How do the MSFW youth...

  11. 20 CFR 669.620 - How do the MSFW youth program regulations apply to the NFJP program authorized under WIA section...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false How do the MSFW youth program regulations... EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR NATIONAL FARMWORKER JOBS PROGRAM UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT The MSFW Youth Program § 669.620 How do the MSFW youth...

  12. Recovery Act - Sustainable Transportation: Advanced Electric Drive Vehicle Education Program

    SciTech Connect

    Caille, Gary

    2013-12-13

    The collective goals of this effort include: 1) reach all facets of this society with education regarding electric vehicles (EV) and plug–in hybrid electric vehicles (PHEV), 2) prepare a workforce to service these advanced vehicles, 3) create web–based learning at an unparalleled level, 4) educate secondary school students to prepare for their future and 5) train the next generation of professional engineers regarding electric vehicles. The Team provided an integrated approach combining secondary schools, community colleges, four–year colleges and community outreach to provide a consistent message (Figure 1). Colorado State University Ventures (CSUV), as the prime contractor, plays a key program management and co–ordination role. CSUV is an affiliate of Colorado State University (CSU) and is a separate 501(c)(3) company. The Team consists of CSUV acting as the prime contractor subcontracted to Arapahoe Community College (ACC), CSU, Motion Reality Inc. (MRI), Georgia Institute of Technology (Georgia Tech) and Ricardo. Collaborators are Douglas County Educational Foundation/School District and Gooru (www.goorulearning.org), a nonprofit web–based learning resource and Google spin–off.

  13. Auxin acts independently of DELLA proteins in regulating gibberellin levels.

    PubMed

    Reid, James B; Davidson, Sandra E; Ross, John J

    2011-03-01

    Shoot elongation is a vital process for plant development and productivity, in both ecological and economic contexts. Auxin and bioactive gibberellins (GAs), such as GA1, play critical roles in the control of elongation, along with environmental and endogenous factors, including other hormones such as the brassinosteroids. The effect of auxins, such as indole-3-acetic acid (IAA), is at least in part mediated by its effect on GA metabolism, since auxin up-regulates biosynthesis genes such as GA 3-oxidase and GA 20-oxidase and down regulates GA catabolism genes such as GA 2-oxidases, leading to elevated levels of bioactive GA 1. In our recent paper, we have provided evidence that this action of IAA is largely independent of DELLA proteins, the negative regulators of GA action, since the auxin effects are still present in the DELLA-deficient la cry-s genotype of pea. This was a crucial issue to resolve, since like auxin, the DELLAs also promote GA 1 synthesis and inhibit its deactivation. DELLAs are deactivated by GA, and thereby mediate a feedback system by which bioactive GA regulates its own level. However, our recent results, in themselves, do not show the generality of the auxin-GA relationship across species and phylogenetic groups or across different tissue types and responses. Further, they do not touch on the ecological benefits of the auxin-GA interaction. These issues are discussed below as well as the need for the development of suitable experimental systems to allow this process to be examined. PMID:21358281

  14. Brightening up: the effect of the Physician Payment Sunshine Act on existing regulation of pharmaceutical marketing.

    PubMed

    Gorlach, Igor; Pham-Kanter, Genevieve

    2013-01-01

    With the passage of the Physician Payment Sunshine Act as part of the federal health care reform law, pharmaceutical manufacturers are now required to disclose a wide range of payments made by manufacturers to physicians. We review current state regulation of pharmaceutical marketing and consider how the federal sunshine provision will affect existing marketing regulation. We analyze the legal and practical implications of the Physician Payment Sunshine Act.

  15. Brightening up: the effect of the Physician Payment Sunshine Act on existing regulation of pharmaceutical marketing.

    PubMed

    Gorlach, Igor; Pham-Kanter, Genevieve

    2013-01-01

    With the passage of the Physician Payment Sunshine Act as part of the federal health care reform law, pharmaceutical manufacturers are now required to disclose a wide range of payments made by manufacturers to physicians. We review current state regulation of pharmaceutical marketing and consider how the federal sunshine provision will affect existing marketing regulation. We analyze the legal and practical implications of the Physician Payment Sunshine Act. PMID:23581674

  16. The Regulation of Medical Computer Software as a “Device” under the Food, Drug, and Cosmetic Act

    PubMed Central

    Brannigan, Vincent

    1986-01-01

    Recent developments in computer software have raised the possibility that federal regulators may claim to control medical computer software as a “device” under the Food, Drug and Cosmetic Act. The purpose of this paper is to analyze the FDCA to determine whether computer software is included in the statutory scheme, examine constitutional arguments relating to computer software, and discuss regulatory principles that should be taken into account when deciding appropriate regulation. This paper is limited to computer program output used by humans in deciding appropriate medical therapy for a patient.

  17. The regulation of hazardous air pollutants under the Clean Air Act Amendments of 1990: Effects on the Portland cement industry

    SciTech Connect

    Mikols, E.H.; Dougherty, A.

    1996-07-01

    Title III of the 1990 Clean Air Act Amendments (CAAA) addresses the control of hazardous air pollutants (HAPs) from major sources of air pollution in the US. In the CAAA, Congress defined 189 compounds as hazardous air pollutants in need of additional control by the Environmental Protection Agency (EPA). Congress directed EPA to identify the major source categories which emit HAPs and to prepare regulations that would reduce and control future HAP emissions. This paper outlines the activities undertaken by EPA to regulate HAP emissions from Portland cement plants and the program developed by the Portland cement manufacturing industry to cope with Title III.

  18. Federal program for regulating highly hazardous materials finally takes off

    SciTech Connect

    Lessard, P.C.

    1996-11-01

    The Risk Management Program (RMP) rule, Section 112(r) of the Clean Air Act (CAA), was signed on May 24 and finalized on June 20. RMP is one of the most comprehensive, technically based regulatory programs for preventing, detecting and responding to accidental hazardous materials releases to have been issued in recent times. Although facilities have three years to comply, EPA estimates that the rule will affect an estimated 66,000 facilities that store highly hazardous or acutely toxic materials. The 1990 CAA Amendments are designed to prevent accidental releases of highly hazardous chemicals from stationary sources. Two significant regulatory programs that have emerged from the revised CAA are the Process Safety Management (PSM) standard and RMP. PSM is designed to protect employees and regulated by the Occupational Safety and Health Administration. RMP`s purpose is to protect the public and the environment from highly hazardous chemicals. It authorizes EPA to create a list of substances (distinct from the list generated under PSM) known to cause serious adverse effects and to implement a program for accidental chemical release prevention.

  19. The Fair Labor Standards Act and the Child Care Industry--What Regulations Apply.

    ERIC Educational Resources Information Center

    Lee, Elisa

    1996-01-01

    Discusses how the federal Fair Labor Standard Act (FLSA) affects the wages and work hours of child care employees and how FLSA interacts with analogous state laws. Examines how child care centers can determine whether FLSA regulations apply to them, existing exemptions to the current act, minimum wage and overtime, whether training time is working…

  20. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., including complaint processing and compliance reviews, will be governed by the provisions of 29 CFR part 34... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Format of the Job Training Partnership Act... LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the...

  1. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., including complaint processing and compliance reviews, will be governed by the provisions of 29 CFR part 34... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Format of the Job Training Partnership Act... LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the...

  2. 20 CFR 626.4 - Table of contents for the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the Job Training Partnership Act, 20 CFR parts 626-638 and 1005, 1 is as follows: 1 Part 1005 was... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Table of contents for the Job Training..., DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.4 Table...

  3. 20 CFR 626.4 - Table of contents for the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the Job Training Partnership Act, 20 CFR parts 626-638 and 1005, 1 is as follows: 1 Part 1005 was... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Table of contents for the Job Training..., DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.4 Table...

  4. 78 FR 54648 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... Regulation; Information Collection; American Recovery and Reinvestment Act--Reporting Requirements--One-Time... identified by Information Collection 9000- 0168, American Recovery and Reinvestment Act--Reporting..., company name (if any), and ``Information Collection 9000-0168, American Recovery and Reinvestment...

  5. 78 FR 54650 - Federal Acquisition Regulation; Information Collection American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... Regulation; Information Collection American Recovery and Reinvestment Act-Reporting Requirements--One-Time... comments identified by Information Collection 9000- 0167, American Recovery and Reinvestment Act-Reporting.... Instructions: Please submit comments only and cite Information Collection 9000-0167, American Recovery...

  6. 76 FR 40367 - Federal Acquisition Regulation; Information Collection; Buy American Act-Construction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... (Grimberg Decision). Public comments are particularly invited on: Whether this collection of information is..., American Act--Construction (Grimberg Decision), by any of the following methods: ] Regulations.gov : http... Collection 9000-0141,'' American Act--Construction (Grimberg Decision), under the heading ``Enter Keyword...

  7. 76 FR 30978 - Employment and Training Administration Program Year (PY) 2011 Workforce Investment Act (WIA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Workforce Investment Act (WIA) Section 167, National Farmworker Jobs Program (NFJP) Allocations AGENCY... PY 2011 for the WIA Title I Section 167 National Farmworker Jobs Program (NFJP) program. The NFJP... Applications (SGA) for the National Farmworker Jobs Program and the National Farmworker Jobs Program...

  8. 78 FR 32364 - Magnuson-Stevens Act Provisions; Interjurisdictional Fisheries Act; Disaster Assistance Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... proposed rule published on January 15, 2009 (74 FR 2467) is withdrawn as of May 30, 2013. FOR FURTHER... Management Act (MSA) and the Interjurisdictional Fisheries Act (IFA), NMFS (on behalf of the Secretary of... disaster assistance provisions of the MSA and the IFA through rulemaking and, thereby, ensure...

  9. BACT analysis under the Clean Air Act's PCD program

    SciTech Connect

    Simms, P.; Walke, J.

    2006-11-15

    Before a company may build a new major industrial source of air pollution, or make modifications to an existing major source in the USA it must apply for and receive a Clean Air Act (CAA) Prevention of Significant Deterioration (PSD) permit. State environmental agencies typically issue such permits, either under state law or by exercising delegated authority to implement the federal PSD program. To fully comply with the CAA, the emissions limits identified as BACT must incorporate consideration of more than just add-on emissions control technology, they must also reflect appropriate considerations of fuel quality (e.g. low-sulfur coal) and process changes (e.g. advanced combustion techniques) as a means of controlling emissions, and must consider the other environmental and public welfare benefits of the identified emissions control options. Several states including New Mexico and Illinois have already determined that innovated technologies, such as Integrated Gasification Combined Cycle (IGCC), must be considered in connection with the BACT analysis for new coal-fired power plants. Even the notion that BACT is categorically limited in scope to the general type of facility proposed is contrary to EPA precedent. For example, the Environmental Appeals Board (EAB) has explained that permitting authorities retain the discretion under the definition of BACT to require dramatically different facility designs (e.g. a natural gas plant instead of a coal-fired power plant). The best advice for any permit applicant is to include in the BACT analysis a careful and honest examination of better performing alternative processes and/or innovative combustion techniques and to aggressively pursue such options wherever feasible. 17 refs.

  10. 77 FR 38717 - Updating Regulations Issued Under the Fair Labor Standards Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Wage and Hour Division 29 CFR Parts 531 and 553 Updating Regulations Issued Under the Fair Labor Standards Act CFR Correction In Title 29 of the Code of Federal Regulations, Parts 500 to 899, revised as of July...

  11. 7 CFR 27.4 - Obligations and rights under Act: not affected by regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Obligations and rights under Act: not affected by regulations. 27.4 Section 27.4 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS...

  12. 7 CFR 27.95 - Spot markets to conform to Act and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Spot markets to conform to Act and regulations. 27.95 Section 27.95 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND...

  13. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  14. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  15. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  16. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  17. 40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and...

  18. 76 FR 78130 - Mortgage Acts and Practices-Advertising (Regulation N); Mortgage Assistance Relief Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... the Bureau, the Bureau is publishing for public comment an interim final rule establishing a new Regulation N (Mortgage Acts and Practices-- Advertising Rule) and a new Regulation O (Mortgage Assistance Relief Services Rule). This interim final rule does not impose any new substantive obligations on...

  19. 75 FR 59609 - Rescission of Regulations Under the Comprehensive Smokeless Tobacco Health Education Act of 1986

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... its smokeless tobacco regulations, 16 CFR Part 307, on November 4, 1986.\\1\\ 51 FR 40015. \\1\\ The... on utilitarian items. 56 FR 11654 (Mar. 20, 1991). II. Basis for Removal of Regulations On June 22... the enactment of the Family Smoking Prevention Act. 75 FR 3665 (Jan. 22, ] 2010). The...

  20. 78 FR 8963 - Update of Existing Privacy Act-NASA Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ... document contains corrections to the final regulations (NASA-2012-0005), which were published in the Federal Register of Thursday, October 4, 2012 (77 FR 60620). The regulations relate to requests to access... SPACE ADMINISTRATION 14 CFR Part 1212 RIN 2700-AD86 Update of Existing Privacy Act--NASA...

  1. Republican States Bolstered Their Health Insurance Rate Review Programs Using Incentives From the Affordable Care Act.

    PubMed

    Fulton, Brent D; Hollingshead, Ann; Karaca-Mandic, Pinar; Scheffler, Richard M

    2015-01-01

    The Affordable Care Act (ACA) included financial and regulatory incentives and goals for states to bolster their health insurance rate review programs, increase their anticipated loss ratio requirements, expand Medicaid, and establish state-based exchanges. We grouped states by political party control and compared their reactions across these policy goals. To identify changes in states' rate review programs and anticipated loss ratio requirements in the individual and small group markets since the ACA's enactment, we conducted legal research and contacted each state's insurance regulator. We linked rate review program changes to the Centers for Medicare and Medicaid Services' (CMS) criteria for an effective rate review program. We found, of states that did not meet CMS's criteria when the ACA was enacted, most made changes to meet those criteria, including Republican-controlled states, which generally oppose the ACA. This finding is likely the result of the relatively low administrative burden associated with reviewing health insurance rates and the fact that doing so prevents federal intervention in rate review. However, Republican-controlled states were less likely than non-Republican-controlled states to increase their anticipated loss ratio requirements to align with the federal retrospective medical loss ratio requirement, expand Medicaid, and establish state-based exchanges, because of their general opposition to the ACA. We conclude that federal incentives for states to strengthen their health insurance rate review programs were more effective than the incentives for states to adopt other insurance-related policy goals of the ACA.

  2. 42 CFR 59a.11 - Programs to which these regulations apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulation (48 CFR chapter 1) do not apply. Any contract awarded pursuant to section 475 of the Act shall be... NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.11 Programs to which.... 286b-6). Grants are awarded to medical libraries to enable them to serve as regional medical...

  3. 42 CFR 59a.11 - Programs to which these regulations apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Regulation (48 CFR chapter 1) do not apply. Any contract awarded pursuant to section 475 of the Act shall be... NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.11 Programs to which.... 286b-6). Grants are awarded to medical libraries to enable them to serve as regional medical...

  4. 42 CFR 59a.11 - Programs to which these regulations apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Regulation (48 CFR chapter 1) do not apply. Any contract awarded pursuant to section 475 of the Act shall be... NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.11 Programs to which.... 286b-6). Grants are awarded to medical libraries to enable them to serve as regional medical...

  5. 42 CFR 59a.11 - Programs to which these regulations apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Regulation (48 CFR chapter 1) do not apply. Any contract awarded pursuant to section 475 of the Act shall be... NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.11 Programs to which.... 286b-6). Grants are awarded to medical libraries to enable them to serve as regional medical...

  6. 42 CFR 59a.11 - Programs to which these regulations apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulation (48 CFR chapter 1) do not apply. Any contract awarded pursuant to section 475 of the Act shall be... NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.11 Programs to which.... 286b-6). Grants are awarded to medical libraries to enable them to serve as regional medical...

  7. 77 FR 61642 - National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... SPACE ADMINISTRATION National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research... the Draft Environmental Impact Statement (DEIS) for the NASA Sounding Rockets Program (SRP) at Poker..., and educational institutions have conducted suborbital rocket launches from the PFRR. While the...

  8. The National Childhood Vaccine Injury Act. The National Vaccine Injury Compensation Program.

    ERIC Educational Resources Information Center

    Clark, Susan G.

    1995-01-01

    Reviews the National Childhood Vaccine Injury Act and the National Vaccine Injury Compensation Program to specifically address the injuries sustained through vaccination. The compensation program allows special education for children permanently injured by vaccines. Analyzes selected cases. (57 footnotes) (MLF)

  9. 76 FR 26220 - Federal Acquisition Regulation; Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... Register of Wednesday, March 16, 2011 (76 FR 14568). The regulations implement section 1347 of the ``Small... Federal Acquisition Regulation; Socioeconomic Program Parity AGENCY: Department of Defense (DoD),...

  10. 75 FR 75469 - Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-03

    ... Children's Health Insurance Program Reauthorization Act of 2009 (Pub. L. 111-3) amended title Xl of the... enacted the Children's Health Insurance Program Reauthorization Act (CHIPRA) of 2009 (Pub. L. 111-3... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  11. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  12. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  13. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Program Fraud Civil Remedies Act (PFCRA). 516.68... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68 Program Fraud Civil Remedies Act (PFCRA). (a) PFCRA was enacted on 21 October 1986 (Public Law 99-509)...

  14. 76 FR 43585 - Bank Secrecy Act Regulations; Definitions and Other Regulations Relating to Money Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... 31 of the Code of Federal Regulations for the BSA regulations. See 75 FR 65806 (October 26, 2010... Proposed Rulemaking, Definitions and Other Regulations Relating to Money Services Businesses, 74 FR 22129... financing of terrorist activities; \\7\\ (2) file Currency Transaction Reports (``CTRs'') \\8\\ and...

  15. Plan, do, study, act model to improve an orientation program.

    PubMed

    Ragsdale, Mary Alice; Mueller, John

    2005-01-01

    The Franciscan Health System has designed a new employee orientation program that is both interactive and thought-provoking. The program has transitioned from a predominantly lecture-based format to one that consists of group discussion, role playing, lunch with senior leaders in the organization, and the utilization of adult learning principles. This article describes the shortcomings of the previous program, gaps identified in the needs assessment, and performance improvement methodology used to enhance the program.

  16. 34 CFR 400.5 - Under what conditions may funds under the Act be used for the joint funding of programs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAMS-GENERAL PROVISIONS § 400.5 Under what conditions may... 34 Education 3 2011-07-01 2011-07-01 false Under what conditions may funds under the Act be used for the joint funding of programs? 400.5 Section 400.5 Education Regulations of the Offices of...

  17. 34 CFR 400.5 - Under what conditions may funds under the Act be used for the joint funding of programs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAMS-GENERAL PROVISIONS § 400.5 Under what conditions may... 34 Education 3 2010-07-01 2010-07-01 false Under what conditions may funds under the Act be used for the joint funding of programs? 400.5 Section 400.5 Education Regulations of the Offices of...

  18. Program for Exceptional Children: Regulations and Procedures.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta. Office of Instructional Services.

    The document reviews state of Georgia and federal law regarding the provision of special education programs for exceptional children and youth and outline procedures for providing those programs. Section I presents a summary of Georgia Chapter 32-6A, particularly the sections which address establishment of other special programs of education;…

  19. 78 FR 45513 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... FR 25818. The matching agreement, as required by 5 U.S.C. 552a(r) of the Privacy Act of 1974, and an... Individuals'', dated February 8, 1996 (February 20, 1996, 61 FR 6427). Dated: July 24, 2013. Aaron Siegel... Base'', November 23, 2011, 76 FR 72391. 3. HHS will be disclosing, as applicable, to DMDC personal...

  20. 78 FR 15733 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Matching and Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12, 2000). Participating Agencies: The Department of Homeland Security/U.S... of Records Notice, 76 FR 58525 (September 21, 2011). NJ-LWD will provide the following to...

  1. 78 FR 15731 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Provisions of Public Law 100-503, the Computer Matching and Privacy ] Protection Act of 1988, 54 FR 25818 (June 19, 1989); and OMB Circular A-130, Appendix I, 65 FR 77677 (December 12, 2000). Participating..., 76 FR 58525 (September 21, 2011). TWC will provide the following to DHS-USCIS: TWC records...

  2. 75 FR 12226 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... 100-503, the Computer Matching and Privacy Protection Act of 1988 (54 FR 25818 (June 19, 1989)) and OMB Circular A-130, Appendix I (65 FR 77677 (December 12, 2000)) notice is ] hereby given of the... Citizenship and Immigration Services, formerly the Immigration and Naturalization Service. SUMMARY:...

  3. Environmental Guidance Program Reference Book: American Indian Religious Freedom Act

    SciTech Connect

    Not Available

    1987-11-01

    This Reference Book contains a copy of the American Indian Religious Freedom Act and guidance for DOE compliance with the statute. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically.

  4. The Americans with Disabilities Act and Child Care Programs.

    ERIC Educational Resources Information Center

    Pardeck, John T.

    1997-01-01

    Discusses the major components of the Americans with Disabilities Act of 1990 applicable to day care facilities. Offers guidelines for admitting disabled children, and for determining whether an accommodation is reasonable or an unreasonable burden. Considers an ADA case involving discrimination against a diabetic child for insights into the…

  5. 75 FR 69988 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Office of Management and Budget (OMB) Guidelines on the Conduct of Matching Programs (54 FR 25818, June... Parties Excluded from Federal Procurements and Nonprocurement Programs, DOJ and ED have determined that... disabilities can obtain this document in an accessible format (e.g., Braille, large print, audiotape,...

  6. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program,...

  7. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits... of the Higher Education Act including the Pell grant program. (a) Coordination. Financial assistance programs under title IV of the Higher Education Act of 1965, as amended (HEA) (the Pell Grant program,...

  8. 78 FR 39901 - Amendments to the 2013 Mortgage Rules Under the Equal Credit Opportunity Act (Regulation B), Real...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... purposes under the mortgage regulations, application of the loan originator compensation rules to bank... Bureau issued Escrow Requirements Under the Truth in Lending Act (Regulation Z), 78 FR 4726 (Jan. 30... Settlement Procedures Act (Regulation X), 78 FR 6856 (Jan. 31, 2013) (2013 HOEPA Final Rule), and Ability...

  9. 77 FR 13388 - Treasury Inspector General for Tax Administration; Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... Treasury Inspector General for Tax Administration; Privacy Act of 1974: Computer Matching Program AGENCY... conduct of TIGTA's computer matching program. DATES: Effective Date: April 5, 2012. ADDRESSES: Comments or... Administration, (202) 622-4068. SUPPLEMENTARY INFORMATION: TIGTA's computer matching program assists in...

  10. 75 FR 24862 - Removing Regulations Implementing the Fish and Wildlife Conservation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ...'' (59 FR 22951), E.O. 13175, and 512 DM 2. We have determined that there are no potential effects. This... Fish and Wildlife Service 50 CFR Part 83 RIN 1018-AX00 Removing Regulations Implementing the Fish and Wildlife Conservation Act AGENCY: Fish and Wildlife Service, Interior. ACTION: Proposed rule. SUMMARY:...

  11. 75 FR 36589 - Financial Crimes Enforcement Network; Amendment to the Bank Secrecy Act Regulations-Definitions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... revise the Bank Secrecy Act (``BSA'') regulations applicable to Money Services Businesses with regard to...-bank financial institutions that offer specific services (often in combination) and are without a... Services Business NPRM On May 12, 2009, FinCEN published an NPRM entitled ``Amendment to the Bank...

  12. Impact of Clean Air Act Regulations on Nitrogen Fate and Transport in Neuse River Basin

    EPA Science Inventory

    This study investigated impacts of Clean Air Act Amendment (CAAA) NOx emissions regulations on the fate and transport of nitrogen for two watersheds in the Neuse River Basin, North Carolina, USA from 1990 to 2020. The Soil and Water Assessment Tool (SWAT) and the Community Multi-...

  13. The National Labor Relations Act and the Regulation of Public Employee Collective Bargaining

    ERIC Educational Resources Information Center

    McCann, Walter; Smiley, Stafford

    1976-01-01

    The arguments for and against federal assumption of the responsibility for regulating the relationship between public employers and public employees are analyzed. It is suggested that the National Labor Relations Act should be extended to include them, thereby imposing upon them a duty to bargain collectively. Available from: the Harvard…

  14. 75 FR 40754 - Government in the Sunshine Act Regulations of the National Science Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION 45 CFR Part 614 RIN 3145-AA53 Government in the Sunshine Act Regulations of the National Science Board AGENCY: National Science Board (NSB), National Science Foundation (NSF). ACTION: Direct final...

  15. 77 FR 234 - Rules and Regulations Under the Textile Fiber Products Identification Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ...; ] FEDERAL TRADE COMMISSION 16 CFR Part 303 Rules and Regulations Under the Textile Fiber Products Identification Act AGENCY: Federal Trade Commission (``FTC'' or ``Commission''). ACTION: Extension of the... to the following address: Federal Trade Commission, Office of the Secretary, Room H-113 (Annex...

  16. 75 FR 58390 - Federal Acquisition Regulation; Information Collection; American Recovery and Reinvestment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Regulation; Information Collection; American Recovery and Reinvestment Act-Reporting Requirements--One-Time... extension of a currently approved information collection requirement concerning the American Recovery and... particularly invited on: Whether this collection of information is necessary for the proper performance...

  17. 78 FR 27308 - Loan Originator Compensation Requirements Under the Truth In Lending Act (Regulation Z...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... adopting Sec. 1026.36(i). \\1\\ 78 FR 11279 (Feb. 15, 2013). A. Title XIV Rulemaking Effective Dates In... become effective sooner than January 2014.\\5\\ \\5\\ 77 FR 55272 (Sept. 7, 2012). The Bureau received very... Requirements Under the Truth In Lending Act (Regulation Z); Prohibition on Financing Credit Insurance...

  18. 76 FR 52295 - Amendment of Privacy Act Regulations, Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR 43 CFR Part 2 RIN 1090-AA94 Amendment of Privacy Act Regulations, Request for Comments AGENCY: Office... on October 3, 2011. ADDRESSES: Send written comments, identified by RIN 1090-AA94, by one of...

  19. 76 FR 20569 - Horse Protection Act; Petition for Amendments to Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... Animal and Plant Health Inspection Service 9 CFR Part 11 Horse Protection Act; Petition for Amendments to... changes to our horse protection regulations and our current enforcement practices and related policies... are noting, however, that certain requests in the petition lack authority in the Horse Protection...

  20. 22 CFR 91.1 - Answering inquiries regarding tariff acts and customs regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Answering inquiries regarding tariff acts and customs regulations. 91.1 Section 91.1 Foreign Relations DEPARTMENT OF STATE LEGAL AND RELATED SERVICES... matters upon which hey are not competent to pass....

  1. HANFORD TANK FARM RESOURCE CONVERVATION & RECOVERY ACT (RCRA) CORRECTIVE ACTION PROGRAM

    SciTech Connect

    KRISTOFZSKI, J.G.

    2007-01-15

    As a consequence of producing special nuclear material for the nation's defense, large amounts of extremely hazardous radioactive waste was created at the US Department of Energy's (DOE) Hanford Site in south central Washington State. A little over 50 million gallons of this waste is now stored in 177 large, underground tanks on Hanford's Central Plateau in tank farms regulated under the Atomic Energy Act and the Resource, Conservation, and Recovery Act (RCRA). Over 60 tanks and associated infrastructure have released or are presumed to have released waste in the vadose zone. In 1998, DOE's Office of River Protection established the Hanford Tank Farm RCRA Corrective Action Program (RCAP) to: (1) characterize the distribution and extent of the existing vadose zone contamination; (2) determine how the contamination will move in the future; (3) estimate the impacts of this contamination on groundwater and other media; (4) develop and implement mitigative measures; and (5) develop corrective measures to be implemented as part of the final closure of the tank farm facilities. Since its creation, RCAP has made major advances in each of these areas, which will be discussed in this paper.

  2. 78 FR 60686 - Regulations Implementing the Byrd Amendments to the Black Lung Benefits Act: Determining Coal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ..., 2013 (78 FR 59102). The preamble incorrectly stated that the Office of Information and Regulatory... of Workers' Compensation Programs 20 CFR Parts 718 and 725 RIN 1240-AA04 Regulations Implementing the... Benefits; Correction AGENCY: Office of Workers' Compensation Programs, Labor. ACTION: Final...

  3. LBR-2 earth stations for the ACTS program

    NASA Technical Reports Server (NTRS)

    O'Reilly, Michael; Jirberg, Russell; Spisz, Ernie

    1990-01-01

    Described in this paper is the 'LBR-2' earth station being developed for NASA's Advanced Communications Technology Satellite (ACTS). The LBR-2 is one of two earth station types that operate through the satellite's baseband processor. The LBR-2 is a small VSAT-like earth station that is easily sited on a user's premises, and provides up to 1.792 megabits per second (MBPS) of voice, video, and data communications. Addressed in the paper is the design of the antenna, the rf subsystems, the digital processing equipment, and the user interface equipment.

  4. LBR-2 Earth stations for the ACTS program

    NASA Technical Reports Server (NTRS)

    Oreilly, Michael; Jirberg, Russell; Spisz, Ernie

    1990-01-01

    The Low Burst Rate-2 (LBR-2) earth station being developed for NASA's Advanced Communications Technology Satellite (ACTS) is described. The LBR-2 is one of two earth station types that operate through the satellite's baseband processor. The LBR-2 is a small earth terminal (VSAT)-like earth station that is easily sited on a user's premises, and provides up to 1.792 megabits per second (MBPS) of voice, video, and data communications. Addressed here is the design of the antenna, the rf subsystems, the digital processing equipment, and the user interface equipment.

  5. Market effects of environmental regulation: coal, railroads, and the 1990 Clean Air Act

    SciTech Connect

    Busse, M.R.; Keohane, N.O.

    2007-01-01

    Many environmental regulations encourage the use of 'clean' inputs. When the suppliers of such an input have market power, environmental regulation will affect not only the quantity of the input used but also its price. We investigate the effect of the Title IV emissions trading program for sulfur dioxide on the market for low-sulfur coal. We find that the two railroads transporting coal were able to price discriminate on the basis of environmental regulation and geographic location. Delivered prices rose for plants in the trading program relative to other plants, and by more at plants near a low-sulfur coal source.

  6. 75 FR 5166 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... From the Federal Register Online via the Government Publishing Office SOCIAL SECURITY ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration/Railroad Retirement Board (SSA/RRB))-- Match Number 1308 AGENCY: Social Security Administration...

  7. Ten Years of the Workforce Investment Act (WIA): Interpreting the Research on WIA and Related Programs

    ERIC Educational Resources Information Center

    Decker, Paul T.; Berk, Jillian A.

    2011-01-01

    In 1998, President Clinton signed the federal Workforce Investment Act (WIA). Implemented in 2000, WIA replaced the Job Partnership Training Act (JTPA) as the primary federal job training program. Congress viewed WIA as a way to end "business as usual" in the workforce investment system. WIA aimed to transform the employment and training system by…

  8. Effects of the ACT Raising Safe Kids Parenting Program on Children's Externalizing Problems

    ERIC Educational Resources Information Center

    Knox, Michele; Burkhart, Kimberly; Howe, Tasha

    2011-01-01

    Eighty-seven parents and primary caregivers of children aged 10 years or younger participated in a study examining the effects of the ACT Raising Safe Kids program on children's behavior. It was hypothesized that children of caregivers who complete ACT-RSK would demonstrate reduced behavior problems compared to children of caregivers in a…

  9. 75 FR 69151 - Small Business Jobs Act: 504 Loan Program Debt Refinancing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... ADMINISTRATION Small Business Jobs Act: 504 Loan Program Debt Refinancing AGENCY: U.S. Small Business... notice to announce the location, date, time and agenda for a meeting regarding the Small Business Jobs... Business Jobs Act (Pub. L. 111-240). The purpose of the meeting is for the SBA Office of...

  10. 78 FR 46256 - Security Program, Report of Suspected Crimes, Suspicious Transactions, Catastrophic Acts and Bank...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... From the Federal Register Online via the Government Publishing Office NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Part 748 Security Program, Report of Suspected Crimes, Suspicious Transactions, Catastrophic Acts and Bank Secrecy Act Compliance CFR Correction In Title 12 of the Code of Federal...

  11. 78 FR 35647 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... (OMB) Guidelines on the Conduct of Matching Programs (54 FR 25818 published June 19, 1989), and OMB..., SSA/OEEAS, 60-0059, last published on January 11, 2006 (71 FR 1819). OPM will disclose to SSA a finder file from the Civil Service and Insurance Records, OPM/Central-1, published on March 20, 2008 (73...

  12. 77 FR 74518 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ...) Guidelines on the Conduct of Matching Programs (54 FR 25818 published June 19, 1989), and OMB Circular No. A... SSA's ``1086'' microfilm file when required (71 FR 1796, January 11, 2006). OPM will provide SSA with... Retirement and Insurance Records) on October 8, 1999 (64 FR 54930), as amended on May 3, 2000 (65 FR...

  13. 77 FR 75499 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... the Federal Register at 74 FR 9294 (March 3, 1976), and last amended at 74 FR 29275 (June 19, 2009... required by paragraph 6c of the ``Guidelines on the Conduct of Matching Programs'' issued by OMB (54 FR 25818), as amended by OMB Circular A-130, 65 FR 77677 (2000). A copy of the notice has been provided...

  14. 78 FR 1275 - Privacy Act of 1974; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... of Management and Budget (OMB) Guidelines on the Conduct of Matching Programs (54 FR 25818 published... file when required (71 FR 1796, January 11, 2006). OPM will provide SSA with an electronic finder file... Records) on October 8, 1999 (64 FR 54930), as amended on May 3, 2000 (65 FR 25775). The system of...

  15. Recovery Act. Development of a Model Energy Conservation Training Program

    SciTech Connect

    none,

    2012-07-05

    The overall objective of this project was to develop an updated model Energy Conservation training program for stationary engineers. This revision to the IUOE National Training Fund’s existing Energy Conservation training curriculum is designed to enable stationary engineers to incorporate essential energy management into routine building operation and maintenance tasks. The curriculum uses a blended learning approach that includes classroom, hands-on, computer simulation and web-based training in addition to a portfolio requirement for a workplace-based learning application. The Energy Conservation training program goal is development of a workforce that can maintain new and existing commercial buildings at optimum energy performance levels. The grant start date was July 6, 2010 and the project continued through September 30, 2012, including a three month non-funded extension.

  16. 78 FR 75581 - Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... MANAGEMENT Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the... Affordable Care Act; Establishment of the Multi-State Plan Program for the Affordable Insurance Exchanges... Act of 2008; Technical Amendment to External Review for Multi-State Plan Program'' (78 FR 68240)....

  17. Industry invites regulation: the passage of the Pure Food and Drug Act of 1906.

    PubMed

    Barkan, I D

    1985-01-01

    Ending its 27-year stranglehold on proposals for federal pure food and drug legislation, Congress passed the Pure Food and Drug Act and its companion bill, the Meat Inspection Act, on June 30, 1906. An unprecedented convergence of consumer, scientific, and industrial support in 1906 prompted such action; most industries even planned for it, hoping regulation would restore the competitiveness of their products on weak foreign and domestic markets. The ways in which these interests converged, and the reasons therefore, suggest a change in their relationships to each other and with the federal government as America headed into the twentieth century. PMID:3881052

  18. Industry invites regulation: the passage of the Pure Food and Drug Act of 1906.

    PubMed Central

    Barkan, I D

    1985-01-01

    Ending its 27-year stranglehold on proposals for federal pure food and drug legislation, Congress passed the Pure Food and Drug Act and its companion bill, the Meat Inspection Act, on June 30, 1906. An unprecedented convergence of consumer, scientific, and industrial support in 1906 prompted such action; most industries even planned for it, hoping regulation would restore the competitiveness of their products on weak foreign and domestic markets. The ways in which these interests converged, and the reasons therefore, suggest a change in their relationships to each other and with the federal government as America headed into the twentieth century. Images p21-a p21-b PMID:3881052

  19. New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination.

    PubMed

    Wahls, Wayne P; Davidson, Mari K

    2012-11-01

    How do cells position the Spo11 (Rec12)-dependent initiation of meiotic recombination at hotspots? The mechanisms are poorly understood and a prevailing view is that they differ substantially between phylogenetic groups. However, recent work discovered that individual species have multiple different DNA sequence-specific, protein-DNA complexes that regulate (and are essential for the activation of) recombination hotspots. The cis-acting elements function combinatorially with documented examples of synergism, antagonism and redundancy. Furthermore, we provide evidence that all currently well-defined modules of this multifactorial, cis-acting regulation are conserved functionally between taxa whose latest common ancestor occurred more than 1 billion years ago. Functionally conserved components include the ATF/CREB-family heterodimer Atf1-Pcr1 and its CRE-like DNA site M26, the CCAAT-box-binding complex Php2-Php3-Php5 and the CCAAT-box, and the zinc-finger protein Rst2 and its Oligo-C motif. The newfound multiplicity, functional redundancy and conservation of cis-acting controls constitute a paradigm shift with broad implications. They provide compelling evidence that most meiotic recombination is, like transcription, regulated by sequence-specific protein-DNA complexes. And the new findings provide important mechanistic insight, such as a solution to the conundrum that Prdm9 is a 'master regulator' of--yet is dispensable for--hotspot activity in mammals. PMID:22904082

  20. Prenatal Maternal Stress Programs Infant Stress Regulation

    ERIC Educational Resources Information Center

    Davis, Elysia Poggi; Glynn, Laura M.; Waffarn, Feizal; Sandman, Curt A.

    2011-01-01

    Objective: Prenatal exposure to inappropriate levels of glucocorticoids (GCs) and maternal stress are putative mechanisms for the fetal programming of later health outcomes. The current investigation examined the influence of prenatal maternal cortisol and maternal psychosocial stress on infant physiological and behavioral responses to stress.…

  1. The Maharashtra Felling of Trees (Regulation) (Amendment) Act, 1988 (No. 26 of 1989), 5 August 1989.

    PubMed

    1989-01-01

    Among other things, this Act amends the Maharashtra (India) Felling of Trees (Regulation) Act, 1964, to authorize the Tree Officer to order the planting of trees in any land (other than government-designated drought land) that he thinks does not contain an adequate number of trees. Owners and occupiers of the land must comply with the order, after being given a reasonable opportunity to be heard. If they do not comply, they can be charged for expenses incurred in having the trees planted. In 1989 the government of West Bengal enacted The Indian Forest (West Bengal Amendment) Act, 1989 (No. 22 of 1988) (Calcutta Gazette, Extraordinary, Part III, 3 February 1989). This Act increases the punishment for various infractions of the Indian Forest Act, 1927, as applied to West Bengal and inserts new language relating to the power of officers to stop and search vehicles; the ability of the state government to seize contraband and related tools, vehicles, boats, and cattle; and punishment for abetting offenses delineated by the Act. PMID:12344326

  2. 26 CFR 1.706-2T - Temporary regulations; question and answer under the Tax Reform Act of 1984.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Temporary regulations; question and answer under the Tax Reform Act of 1984. 1.706-2T Section 1.706-2T Internal Revenue INTERNAL REVENUE SERVICE...-2T Temporary regulations; question and answer under the Tax Reform Act of 1984. Question 1:...

  3. 26 CFR 18.0 - Effective date of temporary regulations under the Subchapter S Revision Act of 1982.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 14 2014-04-01 2013-04-01 true Effective date of temporary regulations under the Subchapter S Revision Act of 1982. 18.0 Section 18.0 Internal Revenue INTERNAL REVENUE SERVICE... SUBCHAPTER S REVISION ACT OF 1982 § 18.0 Effective date of temporary regulations under the Subchapter...

  4. 26 CFR 18.0 - Effective date of temporary regulations under the Subchapter S Revision Act of 1982.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Effective date of temporary regulations under the Subchapter S Revision Act of 1982. 18.0 Section 18.0 Internal Revenue INTERNAL REVENUE SERVICE... SUBCHAPTER S REVISION ACT OF 1982 § 18.0 Effective date of temporary regulations under the Subchapter...

  5. 78 FR 45842 - Amendments to the 2013 Mortgage Rules Under the Real Estate Settlement Procedure Act (Regulation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... From the Federal Register Online via the Government Publishing Office BUREAU OF CONSUMER FINANCIAL PROTECTION 12 CFR Parts 1024 and 1026 RIN 3170-AA37 Amendments to the 2013 Mortgage Rules Under the Real Estate Settlement Procedure Act (Regulation X) and the Truth in Lending Act (Regulation Z) Correction...

  6. 76 FR 14566 - Federal Acquisition Regulation; Socioeconomic Program Parity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... NASA published a proposed rule under FAR Case 2006- 034 in the Federal Register at 73 FR 12699, March... Women- owned Small Business (WOSB) Federal Contract Program final rule, (75 FR 62258, October 7, 2010... 9000-AL88 Federal Acquisition Regulation; Socioeconomic Program Parity AGENCY: Department of...

  7. State Plan for the Adult Basic Education Program under the Adult Education Act of 1966.

    ERIC Educational Resources Information Center

    Nevada State Dept. of Education, Carson City.

    The Nevada State Plan for an adult basic education program provides the legal basis for qualifying for Federal funds under the Adult Education Act of 1966. The State Board of Education will administer the program as an integral part of the State System of Public School Adult and Vocational Education, but other agencies (Federal, State, municipal,…

  8. Magnet Schools and Desegregation: Study of the Emergency School Aid Act Magnet School Program. Summary Report.

    ERIC Educational Resources Information Center

    Royster, Eugene C.; And Others

    This paper is a summary report of the "Study of the Emergency School Aid Act Magnet School Program" which was undertaken to determine the effectiveness of magnet school programs as a strategy in school desegregation. The representative sample of eighteen schools used in the study and their community contexts are described, and the relationship of…

  9. Staff Training Program. Final Report. Title IV, Civil Rights Act of 1964.

    ERIC Educational Resources Information Center

    Clark County School District, Las Vegas, NV.

    Contents of this final progress report of staff training programs funded under Title IV, Civil Rights Act of 1964 include: guidelines for progress report; the integration effort brought up-to-date; project proposal activities for the period being reported; evaluation; dissemination; program changes; personnel; and problem areas and…

  10. Recommendations for Choice Program Provisions in the Elementary and Secondary Education Act. Issue Brief No. 3

    ERIC Educational Resources Information Center

    National Coalition on School Diversity (NJ1), 2012

    2012-01-01

    This policy brief addresses several key provisions in the Elementary and Secondary Education Act that provide policy support and funding to states and localities seeking to deconcentrate poverty and reduce racial isolation in schools. These "choice" programs which include the Magnet Schools Assistance Program and the Voluntary School Choice…

  11. 78 FR 40196 - National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ..., 2012 (77 FR 59611), NASA published its own NOA of the DEIS on October 10, 2012 (77 FR 61642). In... SPACE ADMINISTRATION National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research... the Final Environmental Impact Statement (FEIS) for the NASA Sounding Rockets Program (SRP) at...

  12. 75 FR 77642 - Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Priority Setting for the Children's Health Insurance Program Reauthorization Act (CHIPRA) Pediatric Quality Measures Program--Notice of Correction...

  13. Evaluation of the Fiscal 1989 Education Consolidation and Improvement Act (ECIA) Chapter 1 Program.

    ERIC Educational Resources Information Center

    Kimbrough, Ted D.

    This report evaluates the Education Consolidation and Improvement Act (ECIA) Chapter 1 program in the Chicago (Illinois) Public Schools for 1988-89. The purpose of the program was to serve the most educationally needy students residing in eligible school attendance areas through supplementary and categorical activities. Services were scheduled in…

  14. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  15. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  16. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  17. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  18. 20 CFR 356.2 - Program Fraud Civil Remedies Act of 1986.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Program Fraud Civil Remedies Act of 1986. 356.2 Section 356.2 Employees' Benefits RAILROAD RETIREMENT BOARD ADMINISTRATIVE REMEDIES FOR FRAUDULENT CLAIMS OR STATEMENTS CIVIL MONETARY PENALTY INFLATION ADJUSTMENT § 356.2 Program Fraud Civil Remedies...

  19. 30 CFR 843.25 - Energy Policy Act enforcement in States with approved State programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Energy Policy Act enforcement in States with approved State programs. 843.25 Section 843.25 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL ENFORCEMENT § 843.25 Energy Policy...

  20. 77 FR 43639 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... From the Federal Register Online via the Government Publishing Office SOCIAL SECURITY ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA.... ACTION: Notice of a renewal of an existing computer matching program that expired on May 10,...

  1. Recovery Act: Training Program Development for Commercial Building Equipment Technicians

    SciTech Connect

    Leah Glameyer

    2012-07-12

    The overall goal of this project has been to develop curricula, certification requirements, and accreditation standards for training on energy efficient practices and technologies for commercial building technicians. These training products will advance industry expertise towards net-zero energy commercial building goals and will result in a substantial reduction in energy use. The ultimate objective is to develop a workforce that can bring existing commercial buildings up to their energy performance potential and ensure that new commercial buildings do not fall below their expected optimal level of performance. Commercial building equipment technicians participating in this training program will learn how to best operate commercial buildings to ensure they reach their expected energy performance level. The training is a combination of classroom, online and on-site lessons. The Texas Engineering Extension Service (TEEX) developed curricula using subject matter and adult learning experts to ensure the training meets certification requirements and accreditation standards for training these technicians. The training targets a specific climate zone to meets the needs, specialized expertise, and perspectives of the commercial building equipment technicians in that zone. The combination of efficient operations and advanced design will improve the internal built environment of a commercial building by increasing comfort and safety, while reducing energy use and environmental impact. Properly trained technicians will ensure equipment operates at design specifications. A second impact is a more highly trained workforce that is better equipped to obtain employment. Organizations that contributed to the development of the training program include TEEX and the Texas Engineering Experiment Station (TEES) (both members of The Texas A&M University System). TEES is also a member of the Building Commissioning Association. This report includes a description of the project

  2. New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination

    PubMed Central

    Wahls, Wayne P.; Davidson, Mari K.

    2012-01-01

    How do cells position the Spo11 (Rec12)-dependent initiation of meiotic recombination at hotspots? The mechanisms are poorly understood and a prevailing view is that they differ substantially between phylogenetic groups. However, recent work discovered that individual species have multiple different DNA sequence-specific, protein–DNA complexes that regulate (and are essential for the activation of) recombination hotspots. The cis-acting elements function combinatorially with documented examples of synergism, antagonism and redundancy. Furthermore, we provide evidence that all currently well-defined modules of this multifactorial, cis-acting regulation are conserved functionally between taxa whose latest common ancestor occurred more than 1 billion years ago. Functionally conserved components include the ATF/CREB-family heterodimer Atf1-Pcr1 and its CRE-like DNA site M26, the CCAAT-box-binding complex Php2-Php3-Php5 and the CCAAT-box, and the zinc-finger protein Rst2 and its Oligo-C motif. The newfound multiplicity, functional redundancy and conservation of cis-acting controls constitute a paradigm shift with broad implications. They provide compelling evidence that most meiotic recombination is, like transcription, regulated by sequence-specific protein–DNA complexes. And the new findings provide important mechanistic insight, such as a solution to the conundrum that Prdm9 is a ‘master regulator’ of—yet is dispensable for—hotspot activity in mammals. PMID:22904082

  3. 20 CFR 645.430 - How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Investment Act regulations at 20 CFR 663.620, the local WtW formula grant program operator is a required partner in the One-Stop system. 20 CFR part 662 describes the roles of such partners in the One-Stop... CFR 662.300, such as containing provisions relating to the services to be provided through the...

  4. 20 CFR 645.430 - How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Investment Act regulations at 20 CFR 663.620, the local WtW formula grant program operator is a required partner in the One-Stop system. 20 CFR part 662 describes the roles of such partners in the One-Stop... CFR 662.300, such as containing provisions relating to the services to be provided through the...

  5. 20 CFR 645.430 - How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Investment Act regulations at 20 CFR 663.620, the local WtW formula grant program operator is a required partner in the One-Stop system. 20 CFR part 662 describes the roles of such partners in the One-Stop... CFR 662.300, such as containing provisions relating to the services to be provided through the...

  6. 20 CFR 645.430 - How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Investment Act regulations at 20 CFR 663.620, the local WtW formula grant program operator is a required partner in the One-Stop system. 20 CFR part 662 describes the roles of such partners in the One-Stop... CFR 662.300, such as containing provisions relating to the services to be provided through the...

  7. 20 CFR 645.430 - How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Investment Act regulations at 20 CFR 663.620, the local WtW formula grant program operator is a required partner in the One-Stop system. 20 CFR part 662 describes the roles of such partners in the One-Stop... CFR 662.300, such as containing provisions relating to the services to be provided through the...

  8. Emergency Immigration Education Act Programs. Summer ESL Welcome Program for Students of Limited English Proficiency, Summer Bilingual Program, Projects Omega, Wise, and Bell. Summer 1994. OER Report.

    ERIC Educational Resources Information Center

    Roman, Elliott M.

    The Emergency Immigration Education Act supported three distinct programs in New York City in the summer of 1994: (1) the Summer English as a Second Language (ESL) Welcome Program for Students of Limited English Proficiency; (2) the Summer Bilingual Program; and (3) Projects Omega, Wise, and Bell. The projects served 3,443 students in all. The…

  9. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part, and if so what must I do? 1271.10 Section 1271.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED...

  10. Programming and regulation of metabolic homeostasis.

    PubMed

    Wilson, David F

    2015-03-15

    Evidence is presented that the rate and equilibrium constants in mitochondrial oxidative phosphorylation set and maintain metabolic homeostasis in eukaryotic cells. These internal constants determine the energy state ([ATP]/[ADP][Pi]), and the energy state maintains homeostasis through a bidirectional sensory/signaling control network that reaches every aspect of cellular metabolism. The energy state is maintained with high precision (to ∼1 part in 10(10)), and the control system can respond to transient changes in energy demand (ATP utilization) of more than 100 times the resting rate. Epigenetic and environmental factors are able to "fine-tune" the programmed set point over a narrow range to meet the special needs associated with cell differentiation and chronic changes in metabolic requirements. The result is robust across-platform control of metabolism, which is essential to cellular differentiation and the evolution of complex organisms. A model of oxidative phosphorylation is presented, for which the steady-state rate expression has been derived and computer programmed. The behavior of oxidative phosphorylation predicted by the model is shown to fit the experimental data available for isolated mitochondria as well as for cells and tissues. This includes measurements from several different mammalian tissues as well as from insect flight muscle and plants. The respiratory chain and oxidative phosphorylation is remarkably similar for all higher plants and animals. This is consistent with the efficient synthesis of ATP and precise control of metabolic homeostasis provided by oxidative phosphorylation being a key to cellular differentiation and the evolution of structures with specialized function.

  11. HIPAA Mental Health Parity Act--IRS. Notice of proposed rulemaking by cross-reference to temporary regulations.

    PubMed

    1997-12-22

    Elsewhere in this issue of the Federal Register, the IRS is issuing temporary regulations relating to mental health parity requirements imposed on group health plans. These requirements were added to the Internal Revenue Code by section 1532 of the Taxpayer Relief Act of 1997. The IRS is issuing the temporary regulations at the same time that the Pension and Welfare Benefits Administration of the U.S. Department of Labor and the Health Care Financing Administration of the U.S. Department of Health and Human Services are issuing substantially similar interim final regulations relating to mental health parity requirements added by the Mental Health Parity Act of 1996 to the Employee Retirement Income Security Act of 1974 and the Public Health Service Act. The temporary regulations provide guidance to employers and group health plans relating to the new mental health parity requirements. The text of those temporary regulations also serves as the text of these proposed regulations.

  12. USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase

    PubMed Central

    Fan, Yihui; Mao, Renfang; Yu, Yang; Liu, Shangfeng; Shi, Zhongcheng; Cheng, Jin; Zhang, Huiyuan; An, Lei; Zhao, Yanling; Xu, Xin; Chen, Zhenghu; Kogiso, Mari; Zhang, Dekai; Zhang, Hong; Zhang, Pumin; Jung, Jae U.; Li, Xiaonan

    2014-01-01

    Lys63-linked polyubiquitination of RIG-I is essential in antiviral immune defense, yet the molecular mechanism that negatively regulates this critical step is poorly understood. Here, we report that USP21 acts as a novel negative regulator in antiviral responses through its ability to bind to and deubiquitinate RIG-I. Overexpression of USP21 inhibited RNA virus–induced RIG-I polyubiquitination and RIG-I–mediated interferon (IFN) signaling, whereas deletion of USP21 resulted in elevated RIG-I polyubiquitination, IRF3 phosphorylation, IFN-α/β production, and antiviral responses in MEFs in response to RNA virus infection. USP21 also restricted antiviral responses in peritoneal macrophages (PMs) and bone marrow–derived dendritic cells (BMDCs). USP21-deficient mice spontaneously developed splenomegaly and were more resistant to VSV infection with elevated production of IFNs. Chimeric mice with USP21-deficient hematopoietic cells developed virus-induced splenomegaly and were more resistant to VSV infection. Functional comparison of three deubiquitinases (USP21, A20, and CYLD) demonstrated that USP21 acts as a bona fide RIG-I deubiquitinase to down-regulate antiviral response independent of the A20 ubiquitin-editing complex. Our studies identify a previously unrecognized role for USP21 in the negative regulation of antiviral response through deubiquitinating RIG-I. PMID:24493797

  13. Risk adjustment under the Affordable Care Act: a guide for federal and state regulators.

    PubMed

    Hall, Mark A

    2011-05-01

    To achieve the aims of the Affordable Care Act, state and federal regulators must construct an effective system of risk adjustment, one that protects health insurers that attract a disproportionate share of patients with poor health risks. This brief, which summarizes a Commonwealth Fund–supported conference of leading risk adjustment experts, explores the challenges regulators will face, considers the consequences of the law's risk adjustment provisions, and analyzes the merits of different risk adjustment strategies. Among other recommendations, the brief suggests that regulators use diagnostic rather than only demographic risk measures, that they allow states some but limited flexibility to tailor risk adjustment methods to local circumstances, and that they phase in the use of risk transfer payments to give insurers more time to predict and understand the full effects of risk adjustment.

  14. Head Start Program Regulations and Program Guidance for Parts 1304 and 1308. Revised.

    ERIC Educational Resources Information Center

    Administration for Children, Youth, and Families (DHHS), Washington, DC. Head Start Bureau.

    Head Start and Early Head Start are comprehensive child development programs providing services to children from birth to age 5, pregnant women, and their families. The Head Start Program Performance Standards, mandatory regulations that grantees and delegate agencies must implement in order to operate a Head Start program, are designed to ensure…

  15. Maryland's efforts to develop regulations creating an air emissions offset trading program

    SciTech Connect

    Guy, D.M.; Zaw-Mon, M.

    1999-07-01

    Under the federal Clean Air Act's New Source Review program, many companies located in or planning to locate in areas that do not meet federal air quality standards or in the Northeast Ozone Transport Region (northern Virginia to Maine) must obtain emission reductions (called offsets) of volatile organic compounds and nitrogen oxides that are greater than the new emissions that will be released. This offset requirement allows growth in industry while protecting air quality against deterioration. Despite the federal offset requirement, a formal banking and trading program is not mandated by the Clean Air Act Amendments of 1990. Still, a mechanism is needed to ensure that emission reduction credits (ERCs) are available for sources to use to meet the offset requirement. Currently, Maryland does not have regulations covering the sale or transfer of ERCs from one facility to another. Maryland works with industry on a case-by-case basis to identify potential sources of ERCs and to assist in obtaining them. Then, the offset requirement and the ERCs used to meet the offsets are incorporated into individual permits using various permitting mechanisms. Desiring certainty and stability in the banking and trading process, Maryland's business community has pressed for regulations to formalize Maryland's procedures. Working over several years through a stakeholder process, Maryland has developed concepts for a trading program and a draft regulation. This paper describes Maryland's current case-by-case banking and trading procedure and traces efforts to develop a regulation to formalize the process. The paper discusses complex policy issues related to establishing a banking and trading program, describes the principal elements of Maryland's draft regulation, and summarizes elements of other states' emissions banking and trading programs.

  16. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  17. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  18. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE TRIBAL CLEAN AIR ACT AUTHORITY Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act program...

  19. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... eligibility determination and Clean Air Act program approval. 49.7 Section 49.7 Protection of Environment... MANAGEMENT Tribal Authority § 49.7 Request by an Indian tribe for eligibility determination and Clean Air Act... it meets the eligibility requirements of § 49.6 for Clean Air Act program approval. The...

  20. 45 CFR 90.3 - What programs or activities does the Age Discrimination Act of 1975 cover?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Discrimination Act of 1975 cover? 90.3 Section 90.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES... FINANCIAL ASSISTANCE General § 90.3 What programs or activities does the Age Discrimination Act of 1975 cover? (a) The Age Discrimination Act of 1975 applies to any program or activity receiving...

  1. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation... ethanol violation. Blend into gasoline denatured ethanol with a sulfur content higher than 30 ppm. (f)...

  2. Federal privacy regulations and the provision of Early Hearing Detection and Intervention programs.

    PubMed

    Houston, K Todd; Behl, Diane D; White, Karl R; Forsman, Irene

    2010-08-01

    To be successful, Early Hearing Detection and Intervention (EHDI) programs require individually identifiable information about children to be shared among people who are responsible for screening, diagnosis, early intervention, family support, and medical home services. Pediatricians and other stakeholders in the EHDI process often point to federal laws that were passed to ensure privacy and confidentiality in health care and educational programs as major obstacles to achieving efficient and effective EHDI programs. In this article we summarize the provisions of 3 federal laws (the Health Insurance Portability and Accountability Act [HIPAA], the Family Education Rights and Privacy Act [FERPA], and Part C privacy regulations of the Individuals With Disabilities Education Act [IDEA]) that most directly affect information-sharing in EHDI programs. We suggest strategies for sharing the information needed to operate successful EHDI programs while remaining in compliance with these laws, including obtaining signed parental consent to share information between providers, including an option on the individual family services plan for parents to permit sharing of the plan with pediatricians and other providers, and giving copies of all relevant test results to parents to share with providers as they wish.

  3. 78 FR 13298 - Notice of Retrospective Review of the Americans With Disabilities Act Regulations for Over-the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... Statement in the Federal Register published on April 11, 2000 (65 FR 19477). FOR FURTHER INFORMATION CONTACT... Act Regulations for Over-the-Road Bus Operators; Request for Comments AGENCY: Office of the Secretary...) implementing regulations for over-the-road bus (OTRB) operators. The DOT will review regulations specified...

  4. ATH1 and KNAT2 proteins act together in regulation of plant inflorescence architecture.

    PubMed

    Li, Yang; Pi, Limin; Huang, Hai; Xu, Lin

    2012-02-01

    The inflorescence of flowering plants is a highly organized structure, not only contributing to plant reproductive processes, but also constituting an important part of the entire plant morphology. Previous studies have revealed that the class-I KNOTTED1-like homeobox (KNOX) genes BREVIPEDICELLUS (BP or KNAT1), KNAT2, and KNAT6 play essential roles in inflorescence architecture. Pedicel morphology is known to contribute greatly to inflorescence architecture, and BP negatively regulates KNAT2 and KNAT6 to ensure that pedicels have a normal upward-pointing orientation. These findings indicate that a genetic network exists in controlling pedicel orientation, but how this network functions in the developmental process remains elusive. Here it is reported that the ARABIDOPSIS THALIANA HOMEOBOX GENE1 (ATH1) gene, which belongs to the BELL1-like homeodomain gene family, is a new member participating in regulating pedicel orientation in the class-I KNOX network. In a genetic screening for suppressors of isoginchaku-2D, a gain-of-function ASYMMETRIC LEAVES2 mutant that displays downward-pointing pedicels, a suppressor mutant was obtained. Characterization of this mutant revealed that the mutation corresponds to ATH1. Genetic analysis indicated that ATH1 acts mainly in the KNAT2 pathway. Yeast two-hybrid and bimolecular fluorescence complementation assays demonstrated that ATH1 physically interacts with KNAT2. The data indicate that the ATH1-KNAT2 complex acts redundantly with KNAT6, both of which are negatively regulated by BP during pedicel development.

  5. The Clean Air Act strictly regulates electric utility emissions and utilities are reducing their emissions significantly

    SciTech Connect

    Kinsman, J.D.

    1998-12-31

    Electric utility SO{sub 2} and NO{sub x} emissions have been reduced tremendously, beginning before the first deadlines (1995 for SO{sub 2} and 1996 for NO{sub x}) of the 1990 Clean Air Act Amendments. For the Acid Rain Program, EPA reports that: (1) all 445 affected facilities demonstrated 100 percent compliance for both pollutants and even exceeded the compliance targets; (2) the Acid Rain Program has been very successful; and (3) due to these and other controls, air quality has improved in the United States. Furthermore, the new 8-hour ozone standard, the new PM2.5 standards, the EPA`s 22-state regional NO{sub x} program, the Northeast state petitions for upwind NO{sub x} reductions and EPA`s regional haze proposal will likely lead to substantially greater reductions of utility SO{sub 2} and NO{sub x}.

  6. Nuclear power meets the 101st Congress, a {open_quotes}one-act{close_quotes} comedy: Regulation of Nuclear Regulatory Commission licensees under the Clean Air Act

    SciTech Connect

    Goldsmith, R.

    1992-12-31

    In the Clean Air Act Amendments of 1977, Congress directed the Environmental Protection Agency (EPA) to regulate all radioactive pollutants, including those emitted from facilities licensed and regulated under the Atomic Energy Act (AEA) by the Nuclear Regulatory Commission (NRC). Thus began the era of so-called {open_quotes}dual regulation.{close_quotes} Thirteen years later, that era ended with the passage of section 112(d)(9) of the Clean Air Act Amendments of 1990, which authorized the EPA to refrain from regulating any category of NRC-licensed facility if it found that NRC regulation was adequate to protect public health. This story of how Congress reversed regulatory policy is actually a story more about nuclear power than air pollution. Dual regulation was authorized in 1977 because of two concerns: fears about the public health risks associated with the nation`s growing commitment to nuclear power and doubts about the integrity of nuclear regulation by the NRC. Although neither of these concerns had abated by 1990, the legislative process was so adroitly manipulated by the proponents of nuclear power that Congress, unwittingly, restored the NRC`s regulatory monopoly.

  7. 75 FR 26847 - Privacy Act of 1974; Report of Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ...),'' published at 74 FR 29275 (June 19, 2009). The SSA records will come from the Earnings Recording and Self... Management and Budget (OMB). This notice is provided in accordance with the provisions of the Privacy Act of... to the Director, Regulations Management (02REG), Department of Veterans Affairs, 810 Vermont Ave.,...

  8. 75 FR 66245 - HUD Programs: Violence Against Women Act Conforming Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... notice, which was published on March 16, 2007 (72 FR 12696), provided an overview of the key VAWA... regulations to the VAWA requirements. The November 28, 2008, interim rule, found at 73 FR 72336, ] presented... (73 FR 72336) amended those regulations for HUD's covered programs that required changes to conform...

  9. The Arabidopsis LYST INTERACTING PROTEIN 5 Acts in Regulating Abscisic Acid Signaling and Drought Response.

    PubMed

    Xia, Zongliang; Huo, Yongjin; Wei, Yangyang; Chen, Qiansi; Xu, Ziwei; Zhang, Wei

    2016-01-01

    Multivesicular bodies (MVBs) are unique endosomes containing vesicles in the lumens and play essential roles in many eukaryotic cellular processes. The Arabidopsis LYST INTERACTING PROTEIN 5 (LIP5), a positive regulator of MVB biogenesis, has critical roles in biotic and abiotic stress responses. However, whether the abscisic acid (ABA) signaling is involved in LIP5-mediated stress response is largely unknown. Here, we report that LIP5 functions in regulating ABA signaling and drought response in Arabidopsis. Analyses of a LIP5 promoter-β-glucuronidase (GUS) construct revealed substantial GUS activity in whole seedlings. The expression of LIP5 was induced by ABA and drought, and overexpression of LIP5 led to ABA hypersensitivity, enhanced stomatal closure, reduced water loss, and, therefore, increased drought tolerance. On the contrary, LIP5 knockdown mutants showed ABA-insensitive phenotypes and reduced drought tolerance; suggesting that LIP5 acts in regulating ABA response. Further analysis using a fluorescent dye revealed that ABA and water stress induced cell endocytosis or vesicle trafficking in a largely LIP5-dependent manner. Furthermore, expression of several drought- or ABA-inducible marker genes was significantly down-regulated in the lip5 mutant seedlings. Collectively, our data suggest that LIP5 positively regulates drought tolerance through ABA-mediated cell signaling. PMID:27313589

  10. The Arabidopsis LYST INTERACTING PROTEIN 5 Acts in Regulating Abscisic Acid Signaling and Drought Response

    PubMed Central

    Xia, Zongliang; Huo, Yongjin; Wei, Yangyang; Chen, Qiansi; Xu, Ziwei; Zhang, Wei

    2016-01-01

    Multivesicular bodies (MVBs) are unique endosomes containing vesicles in the lumens and play essential roles in many eukaryotic cellular processes. The Arabidopsis LYST INTERACTING PROTEIN 5 (LIP5), a positive regulator of MVB biogenesis, has critical roles in biotic and abiotic stress responses. However, whether the abscisic acid (ABA) signaling is involved in LIP5-mediated stress response is largely unknown. Here, we report that LIP5 functions in regulating ABA signaling and drought response in Arabidopsis. Analyses of a LIP5 promoter-β-glucuronidase (GUS) construct revealed substantial GUS activity in whole seedlings. The expression of LIP5 was induced by ABA and drought, and overexpression of LIP5 led to ABA hypersensitivity, enhanced stomatal closure, reduced water loss, and, therefore, increased drought tolerance. On the contrary, LIP5 knockdown mutants showed ABA-insensitive phenotypes and reduced drought tolerance; suggesting that LIP5 acts in regulating ABA response. Further analysis using a fluorescent dye revealed that ABA and water stress induced cell endocytosis or vesicle trafficking in a largely LIP5-dependent manner. Furthermore, expression of several drought- or ABA-inducible marker genes was significantly down-regulated in the lip5 mutant seedlings. Collectively, our data suggest that LIP5 positively regulates drought tolerance through ABA-mediated cell signaling. PMID:27313589

  11. Identification of trans-acting factors regulating SamDC expression in Oryza sativa

    SciTech Connect

    Basu, Supratim; Roychoudhury, Aryadeep; Sengupta, Dibyendu N.

    2014-03-07

    Highlights: • Identification of cis elements responsible for SamDC expression by in silico analysis. • qPCR analysis of SamDC expression to abiotic and biotic stress treatments. • Detection of SamDC regulators using identified cis-elements as probe by EMSA. • Southwestern Blot analysis to predict the size of the trans-acting factors. - Abstract: Abiotic stress affects the growth and productivity of crop plants; to cope with the adverse environmental conditions, plants have developed efficient defense machinery comprising of antioxidants like phenolics and flavonoids, and osmolytes like polyamines. SamDC is a key enzyme in the polyamine biosynthesis pathway in plants. In our present communication we have done in silico analysis of the promoter region of SamDC to look for the presence of different cis-regulatory elements contributing to its expression. Based on the presence of different cis-regulatory elements we completed comparative analysis of SamDC gene expression in rice lamina of IR-29 and Nonabokra by qPCR in response to the abiotic stress treatments of salinity, drought, cold and the biotic stress treatments of ABA and light. Additionally, to explore the role of the cis-regulatory elements in regulating the expression of SamDC gene in plants we comparatively analyzed the binding of rice nuclear proteins prepared from IR-29 and Nonabokra undergoing various stress treatments. The intensity of the complex formed was low and inducible in IR-29 in contrast to Nonabokra. Southwestern blot analysis helped in predicting the size of the trans-acting factors binding to these cis-elements. To our knowledge this is the first report on the comprehensive analysis of SamDC gene expression in rice and identification of the trans-acting factors regulating its expression.

  12. Industry's voluntary program: Community Awareness and Emergency Response Program and the Emergency Planning and Community Right-to-Know Act

    SciTech Connect

    Cooper, J.S. )

    1990-10-01

    This paper describes the chemical industry's Community Awareness and Emergency Response (CAER) Program, and voluntary and mandatory actions by the chemical industry to comply with the major environmental legislation. The chemical industry started the voluntary CAER Program soon after the Bhopal Disaster in 1984; it is coordinated through the Chemical Manufacturer's Association. This program, which began in March 1985, is a long-term industry commitment to develop a community outreach program and to improve local emergency response planning. The Congress of the United States began, in 1985, to consider proposals for mandatory programs. This led to enactment of the Superfund Amendments and Reauthorization Act of 1986, known as SARA. A portion of this Act, entitled Title III is also known as the Emergency Planning and Community Right-to-Know Act. Although this legislation has many mandatory requirements, it should be emphasized that a significant degree of voluntary industrial participation is needed if the purposes of the statute are to be achieved. Title III has created an intricate and still evolving system that ties together the EPA, industrial plant managers, state emergency response commissions, local emergency planning committees and fire departments with jurisdiction over the facility. Each of these groups has a different role and responsibilities but must work cooperatively with other participants. Because of the intricate network of participants, the magnitude of the information flow, and the continuing evolution of the system, unique public relations problems exist in order to comply with Title III.

  13. Safety regulation and firm size: effects of the Coal Mine Health and Safety Act of 1969

    SciTech Connect

    Neumann, G.R.; Nelson, J.P.

    1982-10-01

    The Coal Mine Health and Safety Act of 1969 has contributed to the decline in mine productivity, which must be weighed against safer working conditions for the miners. There may be some overstatement of the benefits if only fatalities are considered, however, because there was an increase in non-fatal accidents after 1970. Safety regulations have forced the closure of some small mines and raised some questions about the tradeoffs necessary when work safety reduces competition. A review of pertinent legislation, a hedonic wage-differential model, and the effects of union wage policy are applied to these questions. 4 tables. (DCK)

  14. ACT against Violence Parents Raising Safe Kids Program: Effects on Maltreatment-Related Parenting Behaviors and Beliefs

    ERIC Educational Resources Information Center

    Knox, Michele S.; Burkhart, Kimberly; Hunter, Kimberly E.

    2011-01-01

    The ACT Against Violence Parents Raising Safe Kids program (ACT-PRSK) is an interactive violence prevention program developed by the American Psychological Association for parents of young children. The program teaches and supports parents in the areas of child development, roots and consequences of violence, anger management for adults and…

  15. 20 CFR 627.220 - Coordination with programs under title IV of the Higher Education Act including the Pell grant...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Coordination with programs under title IV of the Higher Education Act including the Pell grant program. 627.220 Section 627.220 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR GENERAL PROVISIONS GOVERNING PROGRAMS UNDER TITLES I, II, AND III OF THE ACT...

  16. Cooperation in USDA studies and evaluations, and full use of federal funds in nutrition assistance programs nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010, Public Law 111-296. Final Rule.

    PubMed

    2011-06-29

    This final rule incorporates into the regulations governing the Programs authorized under the Richard B. Russell National School Lunch Act (NSLA) and the Child Nutrition Act of 1966 (CNA) two nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010 (HHFK Act). The HHFK Act requires State and local cooperation in Department of Agriculture studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also amends the NSLA to stipulate that Federal funds must not be subject to State budget restrictions or limitations, including hiring freezes, work furloughs, and travel restrictions. This final rule amends regulations for the National School Lunch Program; the Special Milk Program for Children; the School Breakfast Program; the Summer Food Service Program; the Child and Adult Care Food Program; State Administrative Expense Funds ; the Special Supplemental Nutrition Program for Women, Infants and Children; and the WIC Farmers' Market Nutrition Program. These provisions will strengthen program integrity by ensuring that sufficient data is made available for studies and evaluations. Additionally, exempting Federal funds from State budgetary restrictions or limitations is intended to increase the ability of State agencies to administer USDA's nutrition assistance programs effectively.

  17. Cooperation in USDA studies and evaluations, and full use of federal funds in nutrition assistance programs nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010, Public Law 111-296. Final Rule.

    PubMed

    2011-06-29

    This final rule incorporates into the regulations governing the Programs authorized under the Richard B. Russell National School Lunch Act (NSLA) and the Child Nutrition Act of 1966 (CNA) two nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010 (HHFK Act). The HHFK Act requires State and local cooperation in Department of Agriculture studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also amends the NSLA to stipulate that Federal funds must not be subject to State budget restrictions or limitations, including hiring freezes, work furloughs, and travel restrictions. This final rule amends regulations for the National School Lunch Program; the Special Milk Program for Children; the School Breakfast Program; the Summer Food Service Program; the Child and Adult Care Food Program; State Administrative Expense Funds ; the Special Supplemental Nutrition Program for Women, Infants and Children; and the WIC Farmers' Market Nutrition Program. These provisions will strengthen program integrity by ensuring that sufficient data is made available for studies and evaluations. Additionally, exempting Federal funds from State budgetary restrictions or limitations is intended to increase the ability of State agencies to administer USDA's nutrition assistance programs effectively. PMID:21721318

  18. The omniscient placenta: Metabolic and epigenetic regulation of fetal programming

    PubMed Central

    Nugent, Bridget M.; Bale, Tracy L.

    2015-01-01

    Fetal development could be considered a sensitive period wherein exogenous insults and changes to the maternal milieu can have long-term impacts on developmental programming. The placenta provides the fetus with protection and necessary nutrients for growth, and responds to maternal cues and changes in nutrient signaling through multiple epigenetic mechanisms. The X-linked enzyme O-linked-N-acetylglucosamine transferase (OGT) acts as a nutrient sensor that modifies numerous proteins to alter various cellular signals, including major epigenetic processes. This review describes epigenetic alterations in the placenta in response to insults during pregnancy, the potential links of OGT as a nutrient sensor to placental epigenetics, and the implications of placental epigenetics in long-term neurodevelopmental programming. We describe the role of placental OGT in the sex-specific programming of hypothalamic-pituitary-adrenal (HPA) axis programming deficits by early prenatal stress as an example of how placental signaling can have long-term effects on neurodevelopment. PMID:26368654

  19. The omniscient placenta: Metabolic and epigenetic regulation of fetal programming.

    PubMed

    Nugent, Bridget M; Bale, Tracy L

    2015-10-01

    Fetal development could be considered a sensitive period wherein exogenous insults and changes to the maternal milieu can have long-term impacts on developmental programming. The placenta provides the fetus with protection and necessary nutrients for growth, and responds to maternal cues and changes in nutrient signaling through multiple epigenetic mechanisms. The X-linked enzyme O-linked-N-acetylglucosamine transferase (OGT) acts as a nutrient sensor that modifies numerous proteins to alter various cellular signals, including major epigenetic processes. This review describes epigenetic alterations in the placenta in response to insults during pregnancy, the potential links of OGT as a nutrient sensor to placental epigenetics, and the implications of placental epigenetics in long-term neurodevelopmental programming. We describe the role of placental OGT in the sex-specific programming of hypothalamic-pituitary-adrenal (HPA) axis programming deficits by early prenatal stress as an example of how placental signaling can have long-term effects on neurodevelopment.

  20. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M.; Hemenway, A.

    1991-12-31

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  1. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    SciTech Connect

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M. ); Hemenway, A. )

    1991-01-01

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protection Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.

  2. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly

    PubMed Central

    Lettice, Laura A.; Horikoshi, Taizo; Heaney, Simon J. H.; van Baren, Marijke J.; van der Linde, Herma C.; Breedveld, Guido J.; Joosse, Marijke; Akarsu, Nurten; Oostra, Ben A.; Endo, Naoto; Shibata, Minoru; Suzuki, Mikio; Takahashi, Eiichi; Shinka, Toshikatsu; Nakahori, Yutaka; Ayusawa, Dai; Nakabayashi, Kazuhiko; Scherer, Stephen W.; Heutink, Peter; Hill, Robert E.; Noji, Sumihare

    2002-01-01

    Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation breakpoint in a PPD patient and a transgenic insertion site in the polydactylous mouse mutant sasquatch (Ssq). The genetic lesions in both lie within the same respective intron of the LMBR1/Lmbr1 gene, which resides ≈1 Mb away from Shh. Genetic analysis of Ssq reveals that the Lmbr1 gene is incidental to the phenotype and that the mutation directly interrupts a cis-acting regulator of Shh. This regulator is most likely the target for generating PPD mutations in human. PMID:12032320

  3. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.

    PubMed

    Lettice, Laura A; Horikoshi, Taizo; Heaney, Simon J H; van Baren, Marijke J; van der Linde, Herma C; Breedveld, Guido J; Joosse, Marijke; Akarsu, Nurten; Oostra, Ben A; Endo, Naoto; Shibata, Minoru; Suzuki, Mikio; Takahashi, Eiichi; Shinka, Toshikatsu; Nakahori, Yutaka; Ayusawa, Dai; Nakabayashi, Kazuhiko; Scherer, Stephen W; Heutink, Peter; Hill, Robert E; Noji, Sumihare

    2002-05-28

    Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation breakpoint in a PPD patient and a transgenic insertion site in the polydactylous mouse mutant sasquatch (Ssq). The genetic lesions in both lie within the same respective intron of the LMBR1/Lmbr1 gene, which resides approximately 1 Mb away from Shh. Genetic analysis of Ssq reveals that the Lmbr1 gene is incidental to the phenotype and that the mutation directly interrupts a cis-acting regulator of Shh. This regulator is most likely the target for generating PPD mutations in human.

  4. The European "clinical trial" regulation; relationship with the Jardé Act: a Giens workshop.

    PubMed

    Lemaire, François; Marchenay, Brigitte; Chassany, Olivier; Barthélémy, Philippe; Bouzzagou, Mohamed; Comet, Denis; Delval, Cécile; Dubray, Claude; Fouret, Cécile; Frija-Orvoen, Elisabeth; Gambotti, Laetitia; Lamarque, Véronique; d'Orsay, Geneviève; Plattner, Valérie; Sibenaler, Claire; Roux, Jacques; Thoby, Frédérique

    2015-01-01

    In May 2014, the European Union Parliament and Council published a new regulation on clinical trials on medicinal products for human use, which is designed to replace Directive 2001/20/EC. It will not come into effect until 2016. Nevertheless, it is essential to examine its relationship with national legislation, i.e. the Jardé Act, whose implementation has been delayed pending publication of the European regulation. The Giens workshop identified and examined the various issues that this relationship is bound to raise. In particular, it looked at trial methodology assessment procedures, the working relationship between the French National Agency of Drug Safety and Health Products (Agence Nationale de Sécurité du Médicament et des Produits de Santé, ANSM) and ethics committees during the authorization application evaluation phase, review of post-authorization/registration studies on medicinal products and medical devices, and data transparency.

  5. The Affordable Care Act and the Medicare program: the engines of true health reform.

    PubMed

    Kinney, Eleanor D

    2013-01-01

    The Patient Protection and Affordable Care Act and its amendments by the Health Care and Education Reconciliation Act of 2010 constitute landmark legislation known as the Affordable Care Act (ACA). The ACA has made many changes in the Medicare program as part of comprehensive health reform for the U.S. health care sector. Title III of the ACA pertains to improving the efficiency and quality of health care. Title VI calls for greater program integrity for all federally funded health insurance programs. Collectively, the changes in Medicare in these two titles address the three major problems that the Medicare program has faced since its inception: cost and volume inflation, quality assurance, and fraud and abuse. These changes, if successfully implemented, will have a dramatic impact on the reform of the American health care sector. The policy-making process in the Medicare program is exemplary of the process of "muddling through," as described by the Yale economist Charles E. Lindblom. Nevertheless, these changes may also prepare the Medicare program to be transformed, through several incremental changes in upcoming years, into a single payer system.

  6. Interactions between Energy Efficiency Programs funded under the Recovery Act and Utility Customer-Funded Energy Efficiency Programs

    SciTech Connect

    Goldman, Charles A.; Stuart, Elizabeth; Hoffman, Ian; Fuller, Merrian C.; Billingsley, Megan A.

    2011-02-25

    Since the spring of 2009, billions of federal dollars have been allocated to state and local governments as grants for energy efficiency and renewable energy projects and programs. The scale of this American Reinvestment and Recovery Act (ARRA) funding, focused on 'shovel-ready' projects to create and retain jobs, is unprecedented. Thousands of newly funded players - cities, counties, states, and tribes - and thousands of programs and projects are entering the existing landscape of energy efficiency programs for the first time or expanding their reach. The nation's experience base with energy efficiency is growing enormously, fed by federal dollars and driven by broader objectives than saving energy alone. State and local officials made countless choices in developing portfolios of ARRA-funded energy efficiency programs and deciding how their programs would relate to existing efficiency programs funded by utility customers. Those choices are worth examining as bellwethers of a future world where there may be multiple program administrators and funding sources in many states. What are the opportunities and challenges of this new environment? What short- and long-term impacts will this large, infusion of funds have on utility customer-funded programs; for example, on infrastructure for delivering energy efficiency services or on customer willingness to invest in energy efficiency? To what extent has the attribution of energy savings been a critical issue, especially where administrators of utility customer-funded energy efficiency programs have performance or shareholder incentives? Do the new ARRA-funded energy efficiency programs provide insights on roles or activities that are particularly well-suited to state and local program administrators vs. administrators or implementers of utility customer-funded programs? The answers could have important implications for the future of U.S. energy efficiency. This report focuses on a selected set of ARRA-funded energy

  7. Student Financing in the Health Professions: Dependence on and Interactions between the Higher Education Act and the Public Health Service Act Financial Aid Programs: A Background Paper. Draft.

    ERIC Educational Resources Information Center

    Advisory Committee on Student Financial Assistance, Washington, DC.

    This paper identifies issues that underlie student financing of education in the health professions in terms of the interrelationships and interactions between financial aid programs under Title IV of the Higher Education Act and Titles VII and VIII of the Public Health Service Act. Section 1 provides background to the issues by describing…

  8. ACTS propagation experiment discussion: Ka-band propagation measurements using the ACTS propagation terminal and the CSU-CHILL and Space Communications Technology Center Florida propagation program

    NASA Technical Reports Server (NTRS)

    Bringi, V. N.; Chandrasekar, V.; Mueller, Eugene A.; Turk, Joseph; Beaver, John; Helmken, Henry F.; Henning, Rudy

    1993-01-01

    Papers on Ka-band propagation measurements using the ACTS propagation terminal and the Colorado State University CHILL multiparameter radar and on Space Communications Technology Center Florida Propagation Program are discussed. Topics covered include: microwave radiative transfer and propagation models; NASA propagation terminal status; ACTS channel characteristics; FAU receive only terminal; FAU terminal status; and propagation testbed.

  9. Individuals with Disabilities Education Act's Early Childhood Programs: Powerful Vision and Pesky Details

    ERIC Educational Resources Information Center

    Hebbeler, Kathleen; Spiker, Donna; Kahn, Lynne

    2012-01-01

    National policy affects local practice in a variety of ways and through a variety of mechanisms. In this article, the authors examine what has been learned from Individuals With Disabilities Education Act's (IDEA) two early childhood (EC) programs about the power and limitations of policy as a lever to improve the lives of young children.…

  10. 78 FR 65045 - Patient Protection and Affordable Care Act; Program Integrity: Exchange, Premium Stabilization...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... Programs, and Market Standards'' (78 FR 37032), which was published in the Federal Register on June 19... Federal Register on March 11, 2013 (78 FR 15541), related to risk corridors and cost-sharing reduction..., 77 FR 18310 (March 27, 2012). \\2\\ Patient Protection and Affordable Care Act; Standards Related...

  11. 78 FR 8193 - Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors TIME & DATE: 2:00 p.m., Wednesday, February 13, 2013. PLACE: 1325 G Street NW., Suite 800,...

  12. 77 FR 56238 - Finance, Budget & Program. Committee Meeting of the Board of Directors; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program. Committee Meeting of the Board of Directors; Sunshine Act TIME & DATE: 3 p.m., Thursday, September 20, 2012. PLACE: 1325 G Street NW., Suite 800, Boardroom, Washington,...

  13. 78 FR 65716 - Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Sunshine Act Meeting; Finance, Budget & Program Committee Meeting of the Board of Directors TIME & DATE: 2:00 p.m., Thursday, November 7, 2013. PLACE: Telephonic Meeting. STATUS: Open. CONTACT...

  14. 76 FR 55125 - Finance, Budget & Program Committee Meeting of the Board of Directors; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Meeting of the Board of Directors; Sunshine Act TIME AND DATE: 2 p.m., Wednesday, September 7, 2011 PLACE: 1325 G Street, NW., Suite 800, Boardroom, Washington,...

  15. 78 FR 24438 - Board of Directors Finance, Budget & Program Committee: Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Board of Directors Finance, Budget & Program Committee: Sunshine Act Meeting TIME AND DATE: 1:00 p.m., Thursday, May 2, 2013. PLACE: 1325 G Street NW., Suite 800, Boardroom, Washington, DC...

  16. 76 FR 67764 - Finance, Budget & Program Committee Board of Directors Meeting; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... From the Federal Register Online via the Government Publishing Office NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Board of Directors Meeting; Sunshine Act Time & Date: 10 a.m., Thursday, November 3, 2011. Place: 1325 G Street, NW., Suite 800, Boardroom, Washington, DC 20005....

  17. 76 FR 20715 - National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research Range

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... SPACE ADMINISTRATION National Environmental Policy Act; Sounding Rockets Program; Poker Flat Research... Environmental Impact Statement (EIS) and to conduct scoping for continuing sounding rocket operations at Poker...) 824-2319; e-mail: Joshua.A.Bundick@nasa.gov . Additional information about NASA's Sounding...

  18. An Evaluation of the Adults and Children Together (ACT) against Violence Parents Raising Safe Kids Program

    ERIC Educational Resources Information Center

    Portwood, Sharon G.; Lambert, Richard G.; Abrams, Lyndon P.; Nelson, Ellissa Brooks

    2011-01-01

    This study evaluated the effectiveness of the Adults and Children Together (ACT) Against Violence Parents Raising Safe Kids program, developed by the American Psychological Association in collaboration with the National Association for the Education of Young Children, as an economical primary prevention intervention for child maltreatment. Using…

  19. 76 FR 31317 - Privacy Act of 1974, as Amended; Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... Matching and Privacy Protection Act of 1988, 54 FR 25818 (June 19, 1989), and OMB Circular A-130, Appendix... records (18-11-01), which was most recently published in the Federal Register on December 29, 2009 (74 FR... the Federal Register on June 4, 2001 (66 FR 30049-50). 5. Effective Dates of the Matching Program...

  20. Watch, Discover, Think, and Act: A Model for Patient Education Program Development.

    ERIC Educational Resources Information Center

    Bartholomew, L. K.; Shegog, R.; Parcel, G. S.; Gold, R. S.; Fernandez, M.; Czyzewski, D. I.; Sockrider, M. M.; Berlin, N.

    2000-01-01

    Describes the development of the Watch, Discover, Think, and Act asthma self-management computer program for inner-city children with asthma. The intervention focuses on teaching two categories of behaviors: asthma specific behaviors such as taking preventive medication, and self-regulatory processes such as monitoring symptoms and solving asthma…

  1. State Plan for Library Programs Under Library Services and Construction Act as Amended.

    ERIC Educational Resources Information Center

    Hawaii State Dept. of Education, Honolulu. Office of Library Services.

    Hawaii's State Plan for Library Programs under the Library Services and Construction Act includes the following sections: (1.0) General Provisions; (1.1) State Agency (exhibits are: Executive Order No. 19, and the Constitution of the State of Hawaii); (1.2) Free Library Services; (1.3) Tables of Organization; (1.4) Personnel; (1.5) Custody of…

  2. 77 FR 62469 - Defense Logistics Agency Freedom of Information Act Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... of the Secretary 32 CFR Part 300 Defense Logistics Agency 32 CFR Part 1285 RIN 0790-AI87 Defense Logistics Agency Freedom of Information Act Program AGENCY: Defense Logistics Agency, DoD. ACTION: Proposed rule. SUMMARY: The Defense Logistics Agency (DLA) proposes to revise and update its existing...

  3. Aligning School Counselors, Comprehensive School Counseling Programs, and the No Child Left Behind Act of 2001

    ERIC Educational Resources Information Center

    Sabens, Franciene S.; Zyromski, Brett

    2009-01-01

    The No Child Left Behind (NCLB) Act contains numerous implications for school counselors, but the affects of NCLB on school counselors' roles and identities has not been thoroughly explored. Further, ways comprehensive school counseling programs and school counselors can thrive while striving to meet the goals of NCLB have been ignored in previous…

  4. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Program Fraud Civil Remedies Act (PFCRA). 516.68 Section 516.68 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68...

  5. 32 CFR 516.68 - Program Fraud Civil Remedies Act (PFCRA).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Program Fraud Civil Remedies Act (PFCRA). 516.68 Section 516.68 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.68...

  6. Job Training Partnership Act Handbook for DPI/JTPA 8% Programs. 1988-89.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Support Programs.

    This handbook has been developed to assist Job Training Partnership Act (JTPA) coordinators with the information and procedures required for successful implementation of the JTPA in North Carolina public schools. The following are covered: program objectives, job requirements, file checklists, outreach/recruitment, marketing activities, program…

  7. Knowledge of the animal welfare act and animal welfare regulations influences attitudes toward animal research.

    PubMed

    Metzger, Mitchell M

    2015-01-01

    Recent public-opinion polls indicate that Americans have shown a decline in support for animal experimentation, and several reports suggest a relationship between people's knowledge of animal welfare regulations and their attitudes toward animal research. Therefore, this study was designed to assess respondent's knowledge of several provisions in the Animal Welfare Act (AWA) and Animal Welfare Regulations (AWR), and determine whether exposure to elements of this legislation would influence an individual's attitudes toward the use of animals in research. A survey was used to assess knowledge of animal research regulations and attitudes toward animal research from a sample of individuals recruited through Amazon's Mechanical Turk crowdsourcing marketplace. Results from study 1 confirmed the hypothesis that respondents had little knowledge of various federal regulations that govern animal research activities. Data from study 2 revealed that exposure to elements of the AWA and AWR influenced participants' attitudes toward the use of animals in research. These results suggest that providing information to the general public about the AWA and AWR that protect laboratory animals from abuse and neglect may help alleviate concerns about using animals in research settings. PMID:25651094

  8. Knowledge of the Animal Welfare Act and Animal Welfare Regulations Influences Attitudes toward Animal Research

    PubMed Central

    2015-01-01

    Recent public-opinion polls indicate that Americans have shown a decline in support for animal experimentation, and several reports suggest a relationship between people's knowledge of animal welfare regulations and their attitudes toward animal research. Therefore, this study was designed to assess respondent's knowledge of several provisions in the Animal Welfare Act (AWA) and Animal Welfare Regulations (AWR), and determine whether exposure to elements of this legislation would influence an individual's attitudes toward the use of animals in research. A survey was used to assess knowledge of animal research regulations and attitudes toward animal research from a sample of individuals recruited through Amazon's Mechanical Turk crowdsourcing marketplace. Results from study 1 confirmed the hypothesis that respondents had little knowledge of various federal regulations that govern animal research activities. Data from study 2 revealed that exposure to elements of the AWA and AWR influenced participants’ attitudes toward the use of animals in research. These results suggest that providing information to the general public about the AWA and AWR that protect laboratory animals from abuse and neglect may help alleviate concerns about using animals in research settings. PMID:25651094

  9. Knowledge of the animal welfare act and animal welfare regulations influences attitudes toward animal research.

    PubMed

    Metzger, Mitchell M

    2015-01-01

    Recent public-opinion polls indicate that Americans have shown a decline in support for animal experimentation, and several reports suggest a relationship between people's knowledge of animal welfare regulations and their attitudes toward animal research. Therefore, this study was designed to assess respondent's knowledge of several provisions in the Animal Welfare Act (AWA) and Animal Welfare Regulations (AWR), and determine whether exposure to elements of this legislation would influence an individual's attitudes toward the use of animals in research. A survey was used to assess knowledge of animal research regulations and attitudes toward animal research from a sample of individuals recruited through Amazon's Mechanical Turk crowdsourcing marketplace. Results from study 1 confirmed the hypothesis that respondents had little knowledge of various federal regulations that govern animal research activities. Data from study 2 revealed that exposure to elements of the AWA and AWR influenced participants' attitudes toward the use of animals in research. These results suggest that providing information to the general public about the AWA and AWR that protect laboratory animals from abuse and neglect may help alleviate concerns about using animals in research settings.

  10. Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)

    PubMed Central

    Solomon, Oz; Oren, Shirley; Safran, Michal; Deshet-Unger, Naamit; Akiva, Pinchas; Jacob-Hirsch, Jasmine; Cesarkas, Karen; Kabesa, Reut; Amariglio, Ninette; Unger, Ron; Rechavi, Gideon; Eyal, Eran

    2013-01-01

    Alternative mRNA splicing is a major mechanism for gene regulation and transcriptome diversity. Despite the extent of the phenomenon, the regulation and specificity of the splicing machinery are only partially understood. Adenosine-to-inosine (A-to-I) RNA editing of pre-mRNA by ADAR enzymes has been linked to splicing regulation in several cases. Here we used bioinformatics approaches, RNA-seq and exon-specific microarray of ADAR knockdown cells to globally examine how ADAR and its A-to-I RNA editing activity influence alternative mRNA splicing. Although A-to-I RNA editing only rarely targets canonical splicing acceptor, donor, and branch sites, it was found to affect splicing regulatory elements (SREs) within exons. Cassette exons were found to be significantly enriched with A-to-I RNA editing sites compared with constitutive exons. RNA-seq and exon-specific microarray revealed that ADAR knockdown in hepatocarcinoma and myelogenous leukemia cell lines leads to global changes in gene expression, with hundreds of genes changing their splicing patterns in both cell lines. This global change in splicing pattern cannot be explained by putative editing sites alone. Genes showing significant changes in their splicing pattern are frequently involved in RNA processing and splicing activity. Analysis of recently published RNA-seq data from glioblastoma cell lines showed similar results. Our global analysis reveals that ADAR plays a major role in splicing regulation. Although direct editing of the splicing motifs does occur, we suggest it is not likely to be the primary mechanism for ADAR-mediated regulation of alternative splicing. Rather, this regulation is achieved by modulating trans-acting factors involved in the splicing machinery. PMID:23474544

  11. 76 FR 39007 - Native American Graves Protection and Repatriation Act Regulations- Definition of “Indian Tribe”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... Office of the Secretary of the Interior 43 CFR Part 10 RIN 1024-AD98 Native American Graves Protection... regulations implementing the Native American Graves Protection and Repatriation Act (NAGPRA) removes the... implementation of the Native American Graves Protection and Repatriation Act, including the issuance...

  12. Confinement regulates complex biochemical networks: initiation of blood clotting by "diffusion acting".

    PubMed

    Shen, Feng; Pompano, Rebecca R; Kastrup, Christian J; Ismagilov, Rustem F

    2009-10-21

    This study shows that environmental confinement strongly affects the activation of nonlinear reaction networks, such as blood coagulation (clotting), by small quantities of activators. Blood coagulation is sensitive to the local concentration of soluble activators, initiating only when the activators surpass a threshold concentration, and therefore is regulated by mass transport phenomena such as flow and diffusion. Here, diffusion was limited by decreasing the size of microfluidic chambers, and it was found that microparticles carrying either the classical stimulus, tissue factor, or a bacterial stimulus, Bacillus cereus, initiated coagulation of human platelet-poor plasma only when confined. A simple analytical argument and numerical model were used to describe the mechanism for this phenomenon: confinement causes diffusible activators to accumulate locally and surpass the threshold concentration. To interpret the results, a dimensionless confinement number, Cn, was used to describe whether a stimulus was confined, and a Damköhler number, Da(2), was used to describe whether a subthreshold stimulus could initiate coagulation. In the context of initiation of coagulation by bacteria, this mechanism can be thought of as "diffusion acting", which is distinct from "diffusion sensing". The ability of confinement and diffusion acting to change the outcome of coagulation suggests that confinement should also regulate other biological "on" and "off" processes that are controlled by thresholds.

  13. Clean Water Act's Section 404 permit program enters its adolescence: an institutional and programmatic perspective

    SciTech Connect

    Blumm, M.C.

    1980-01-01

    Section 404 of the Clean Water Act deals with permit requirements and has become a major Federal regulatory program. The program's scope and procedures are reviewed, with emphasis given to the responsibilities of the agencies involved and the opportunities for discharging these duties with the maximum efficiency. Interagency and intergovernmental cooperation are crucial to the effectiveness of the broad ranging 404 program. The Environmental Protection Agency's role is seen as one of oversight and guidance, as well as issuing criteria and monitoring enforcement. The appropriate roles for other Federal and state agencies, state governments, Congress, and the public are outlined and also depend on cooperation for effective implementation. 333 references. (DCK)

  14. ACT: a program for calculation of the changes in radiological source terms with time

    SciTech Connect

    Woolfolk, S.W.

    1985-08-12

    The program ACT calculates the source term activity from a set of initial activities as a function of discrete time steps. This calculation considers inbreeding of daughter products. ACT also calculates ''Probable Release'', which is the activity at a given time multiplied by both the fraction released and the probability of the release. The ''Probable Release'' not only assumes that the fraction released is a single step function with time, but that the probability of release is zero for a limited period and it can be described by the ''Wisconsin Regression'' function using time as the independent variable. Finally, the program calculates the time integrated sum of the ''Probable Release'' for each isotope. This program is intended to support analysis of releases from radioactive waste disposal sites such as those required by 40 CFR 191.

  15. ISO New England: Results of Ancillary Service Pilot Programs, Alternative Technology Regulation Pilot Program and Demand Response Reserves Pilot Program

    SciTech Connect

    Lowell, Jon; Yoshimura, Henry

    2011-10-26

    This PowerPoint presentation compares performance of pilot program assets and generation resources in alternative technology regulation and demand response reserves for flywheels and residential electric thermal storage.

  16. Sperm is epigenetically programmed to regulate gene transcription in embryos.

    PubMed

    Teperek, Marta; Simeone, Angela; Gaggioli, Vincent; Miyamoto, Kei; Allen, George E; Erkek, Serap; Kwon, Taejoon; Marcotte, Edward M; Zegerman, Philip; Bradshaw, Charles R; Peters, Antoine H F M; Gurdon, John B; Jullien, Jerome

    2016-08-01

    For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the existence of epigenetic marks on sperm genes, and there are no functional tests supporting the role of sperm epigenetic marking on embryonic gene expression. Here, we show that sperm is epigenetically programmed to regulate embryonic gene expression. By comparing the development of sperm- and spermatid-derived frog embryos, we show that the programming of sperm for successful development relates to its ability to regulate transcription of a set of developmentally important genes. During spermatid maturation into sperm, these genes lose H3K4me2/3 and retain H3K27me3 marks. Experimental removal of these epigenetic marks at fertilization de-regulates gene expression in the resulting embryos in a paternal chromatin-dependent manner. This demonstrates that epigenetic instructions delivered by the sperm at fertilization are required for correct regulation of gene expression in the future embryos. The epigenetic mechanisms of developmental programming revealed here are likely to relate to the mechanisms involved in transgenerational transmission of acquired traits. Understanding how parental experience can influence development of the progeny has broad potential for improving human health. PMID:27034506

  17. Sperm is epigenetically programmed to regulate gene transcription in embryos

    PubMed Central

    Teperek, Marta; Simeone, Angela; Gaggioli, Vincent; Miyamoto, Kei; Allen, George E.; Erkek, Serap; Kwon, Taejoon; Marcotte, Edward M.; Zegerman, Philip; Bradshaw, Charles R.; Peters, Antoine H.F.M.; Gurdon, John B.; Jullien, Jerome

    2016-01-01

    For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the existence of epigenetic marks on sperm genes, and there are no functional tests supporting the role of sperm epigenetic marking on embryonic gene expression. Here, we show that sperm is epigenetically programmed to regulate embryonic gene expression. By comparing the development of sperm- and spermatid-derived frog embryos, we show that the programming of sperm for successful development relates to its ability to regulate transcription of a set of developmentally important genes. During spermatid maturation into sperm, these genes lose H3K4me2/3 and retain H3K27me3 marks. Experimental removal of these epigenetic marks at fertilization de-regulates gene expression in the resulting embryos in a paternal chromatin-dependent manner. This demonstrates that epigenetic instructions delivered by the sperm at fertilization are required for correct regulation of gene expression in the future embryos. The epigenetic mechanisms of developmental programming revealed here are likely to relate to the mechanisms involved in transgenerational transmission of acquired traits. Understanding how parental experience can influence development of the progeny has broad potential for improving human health. PMID:27034506

  18. A care improvement program acting as a powerful learning environment to support nursing students learning facilitation competencies.

    PubMed

    Jukema, Jan S; Harps-Timmerman, Annelies; Stoopendaal, Annemiek; Smits, Carolien H M

    2015-11-01

    Change management is an important area of training in undergraduate nursing education. Successful change management in healthcare aimed at improving practices requires facilitation skills that support teams in attaining the desired change. Developing facilitation skills in nursing students requires formal educational support. A Dutch Regional Care Improvement Program based on a nationwide format of change management in healthcare was designed to act as a Powerful Learning Environment for nursing students developing competencies in facilitating change. This article has two aims: to provide comprehensive insight into the program components and to describe students' learning experiences in developing their facilitation skills. This Dutch Regional Care Improvement Program considers three aspects of a Powerful Learning Environment: self-regulated learning; problem-based learning; and complex, realistic and challenging learning tasks. These three aspects were operationalised in five distinct areas of facilitation: increasing awareness of the need for change; leadership and project management; relationship building and communication; importance of the local context; and ongoing monitoring and evaluation. Over a period of 18 months, 42 nursing students, supported by trained lecturer-coaches, took part in nine improvement teams in our Regional Care Improvement Program, executing activities in all five areas of facilitation. Based on the students' experiences, we propose refinements to various components of this program, aimed at strengthenin the learning environment. There is a need for further detailed empirical research to study the impact this kind of learning environment has on students developing facilitation competencies in healthcare improvement.

  19. PVREG - A photovoltaic voltage regulation investigation tool: Program reference manual

    SciTech Connect

    Garrett, D.L.; Sims, T.R.; Jones, R.A.; Jeter, S.M.

    1989-06-01

    This manual provides information for installing and maintaining the computer program PVREG, a program developed to study the impact of distributed photovoltaic systems on the voltage regulation of distribution systems. The manual describes installation on the Apollo workstation or the IBM PC-AT (or compatible), but the instructions and code description should be general enough to assist installation on other computers, also. The manual assumes that the user is well acquainted with the computer on which the program is to operate and with the operating system of that computer. The manual describes the program structure and models in detail and provides step-by-step installation instructions for both the Apollo and AT-compatible computers. 9 figs., 11 tabs.

  20. Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity

    PubMed Central

    Yang, Chao-Shun; Chang, Kung-Yen; Dang, Jason; Rana, Tariq M.

    2016-01-01

    The polycomb repressive complex 1 (PRC1) is a multi-subunit complex that plays critical roles in the epigenetic modulation of gene expression. Here, we show that the PRC1 component polycomb group ring finger 6 (Pcgf6) is required to maintain embryonic stem cell (ESC) identity. In contrast to canonical PRC1, Pcgf6 acts as a positive regulator of transcription and binds predominantly to promoters bearing active chromatin marks. Pcgf6 is expressed at high levels in ESCs, and knockdown reduces the expression of the core ESC regulators Oct4, Sox2, and Nanog. Conversely, Pcgf6 overexpression prevents downregulation of these factors and impairs differentiation. In addition, Pcgf6 enhanced reprogramming in both mouse and human somatic cells. The genomic binding profile of Pcgf6 is highly similar to that of trithorax group proteins, but not of PRC1 or PRC2 complexes, suggesting that Pcgf6 functions atypically in ESCs. Our data reveal novel roles for Pcgf6 in directly regulating Oct4, Nanog, Sox2, and Lin28 expression to maintain ESC identity. PMID:27247273

  1. Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis

    PubMed Central

    Rogers, Edward M.; Spracklen, Andrew J.; Bilancia, Colleen G.; Sumigray, Kaelyn D.; Allred, S. Colby; Nowotarski, Stephanie H.; Schaefer, Kristina N.; Ritchie, Benjamin J.; Peifer, Mark

    2016-01-01

    Abelson family kinases (Abls) are key regulators of cell behavior and the cytoskeleton during development and in leukemia. Abl’s SH3, SH2, and tyrosine kinase domains are joined via a linker to an F-actin–binding domain (FABD). Research on Abl’s roles in cell culture led to several hypotheses for its mechanism of action: 1) Abl phosphorylates other proteins, modulating their activity, 2) Abl directly regulates the cytoskeleton via its cytoskeletal interaction domains, and/or 3) Abl is a scaffold for a signaling complex. The importance of these roles during normal development remains untested. We tested these mechanistic hypotheses during Drosophila morphogenesis using a series of mutants to examine Abl’s many cell biological roles. Strikingly, Abl lacking the FABD fully rescued morphogenesis, cell shape change, actin regulation, and viability, whereas kinase-dead Abl, although reduced in function, retained substantial rescuing ability in some but not all Abl functions. We also tested the function of four conserved motifs in the linker region, revealing a key role for a conserved PXXP motif known to bind Crk and Abi. We propose that Abl acts as a robust multidomain scaffold with different protein motifs and activities contributing differentially to diverse cellular behaviors. PMID:27385341

  2. 12 CFR 335.901 - Delegation of authority to act on matters with respect to disclosure laws and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... respect to disclosure laws and regulations. 335.901 Section 335.901 Banks and Banking FEDERAL DEPOSIT... § 335.901 Delegation of authority to act on matters with respect to disclosure laws and regulations. (a... Supervision and Consumer Protection (DSC), and where confirmed in writing by the director, to a...

  3. Clean Water Act (excluding Section 404). Environmental guidance program reference book: Revision 6

    SciTech Connect

    Not Available

    1993-01-15

    This Reference Book contains a current copy of the Clean Water Act (excluding Section 404) and those regulations that implement the statutes and appear to be most relevant to US Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  4. Toxic Substances Control Act. Environmental Guidance Program Reference Book: Revision 6

    SciTech Connect

    Not Available

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  5. Environmental Guidance Program reference book: Toxic substances control act. Revision 7

    SciTech Connect

    1994-12-01

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  6. 77 FR 5009 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Duke...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... object to a Clean Air Act (Act) Title V operating permit for Duke Energy Indiana--Edwardsport Generating... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Duke Energy Indiana--Edwardsport Generating Station AGENCY: Environmental Protection Agency (EPA)....

  7. 76 FR 43684 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... Energy (Xcel)--Pawnee Power Station. Pursuant to section 505(b)(2) of the Clean Air Act (Act or CAA... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Public Service Company of Colorado dba Xcel Energy--Pawnee Power Station AGENCY: Environmental...

  8. 76 FR 12730 - Clean Air Act Operating Permit Program; Objection to State Operating Permit for U.S. Steel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Clean Air Act Operating Permit Program; Objection to State Operating Permit for U.S. Steel-Granite.... Steel--Granite City Works (USS). Sections 307(b) and 505(b)(2) of the Clean Air Act (Act) provide that...

  9. 75 FR 19968 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for... April 1, 2009 title V permit issued to Public Service Company of Colorado dba Xcel Energy (Xcel)--Hayden Power Station. Pursuant to section 505(b)(2) of the Clean Air Act (Act), Petitioners may seek...

  10. 76 FR 16438 - Reallocation of American Recovery and Reinvestment Act Capital Funds-Capital Fund Grant Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... Grant Program Under the American Recovery and Reinvestment Act of 2009 AGENCY: Office of the Assistant... Reinvestment Act of 2009 (the Recovery Act) included a $4 billion appropriation of Capital Funds for public... competitive process. HUD obligated approximately $2.985 million in formula funds to PHAs on March 18, 2009....

  11. 75 FR 18377 - Supplemental Nutrition Assistance Program, Regulation Restructuring: Issuance Regulation Update...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ...(e). 274.12(n) 274.1(e). Implementation In accordance with the parameters set forth in 62 FR 55141... (48 FR 29115), this Program is excluded from the scope of Executive Order 12372, which requires... / Monday, April 12, 2010 / Rules and Regulations#0;#0; ] DEPARTMENT OF AGRICULTURE Food and...

  12. Patient Protection and Affordable Care Act; establishment of the multi-state plan program for the Affordable Insurance Exchanges.

    PubMed

    2013-03-11

    The U.S. Office of Personnel Management (OPM) is issuing a final regulation establishing the Multi-State Plan Program (MSPP) pursuant to the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act of 2010, referred to collectively as the Affordable Care Act. Through contracts with OPM, health insurance issuers will offer at least two multi-State plans (MSPs) on each of the Affordable Insurance Exchanges (Exchanges). One of the issuers must be non-profit. Under the law, an MSPP issuer may phase in the States in which it offers coverage over 4 years, but it must offer MSPs on Exchanges in all States and the District of Columbia by the fourth year in which the MSPP issuer participates in the MSPP. This rule aims to balance adhering to the statutory goals of MSPP while aligning its standards to those applying to qualified health plans to promote a level playing field across health plans.

  13. atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain

    NASA Technical Reports Server (NTRS)

    Hassan, B. A.; Bermingham, N. A.; He, Y.; Sun, Y.; Jan, Y. N.; Zoghbi, H. Y.; Bellen, H. J.

    2000-01-01

    Drosophila atonal (ato) is the proneural gene of the chordotonal organs (CHOs) in the peripheral nervous system (PNS) and the larval and adult photoreceptor organs. Here, we show that ato is expressed at multiple stages during the development of a lineage of central brain neurons that innervate the optic lobes and are required for eclosion. A novel fate mapping approach shows that ato is expressed in the embryonic precursors of these neurons and that its expression is reactivated in third instar larvae (L3). In contrast to its function in the PNS, ato does not act as a proneural gene in the embryonic brain. Instead, ato performs a novel function, regulating arborization during larval and pupal development by interacting with Notch.

  14. 77 FR 32085 - Privacy Act of 1974, as Amended; Renewal of Computer Matching Program Between the U.S. Department...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Privacy Act of 1974, as Amended; Renewal of Computer Matching Program Between the U.S. Department of... document provides notice of the renewal of the computer matching program between the U.S. Department of... under the Privacy Act of 1974 (5 U.S.C. 552a), as amended by the Computer Matching and...

  15. 75 FR 9012 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/U.S. Department of Health and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ U.S. Department of Health and..., terminating, or denying a person's benefits or payments. B. SSA Computer Matches Subject to the Privacy Act We... existing computer matching program that is scheduled to expire on March 19, 2010. SUMMARY: In...

  16. 77 FR 6620 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/the States); Match 6000 and 6003

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ the States); Match 6000 and 6003 AGENCY: Social Security Administration (SSA). ACTION: Notice of a renewal of an existing computer... Privacy Act, as amended, this notice announces a renewal of an existing computer matching program that...

  17. 77 FR 72581 - Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... Care Act; Establishment of the Multi- State Plan Program for the Affordable Insurance Exchanges... Care Act; Establishment of the Multi-State Plan Program for the Affordable Insurance Exchanges AGENCY... Affordable Insurance Exchanges (Exchanges). Under the law, an MSPP issuer may phase in the States in which...

  18. The Education Consolidation and Improvement Act: Some Changes in Federal Funding of Elementary and Secondary School Programs.

    ERIC Educational Resources Information Center

    Askins, Billy E.

    1984-01-01

    The Education Consolidation and Improvement Act (ECIA), which replaced the Elementary and Secondary Education Act, significantly changed the federal government's role in education. The ECIA is part of a program to consolidate and simplify federal programs, cut federal spending, and transfer power to state and local governments. Fiscal,…

  19. 78 FR 25591 - Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... MANAGEMENT 45 CFR Part 800 RIN 3206-AM47 Patient Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the Affordable Insurance Exchanges; Correction AGENCY: U.S. Office of... Protection and Affordable Care Act; Establishment of the Multi-State Plan Program for the...

  20. Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis

    PubMed Central

    Le Goff, Emilie; Martinand-Mari, Camille; Martin, Marianne; Feuillard, Jérôme; Boublik, Yvan; Godefroy, Nelly; Mangeat, Paul; Baghdiguian, Stephen; Cavalli, Giacomo

    2015-01-01

    ABSTRACT The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial expression domains of their target genes, particularly of Hox genes, starting from mid embryogenesis. The Enhancer of zeste [E(z)] PcG protein is the catalytic subunit of the PRC2 complex, which silences its targets via deposition of the H3K27me3 mark. Here, we studied the ascidian Ciona intestinalis counterpart of E(z). Ci-E(z) is detected by immunohistochemistry as soon as the 2- and 4-cell stages as a cytoplasmic form and becomes exclusively nuclear thereafter, whereas the H3K27me3 mark is detected starting from the gastrula stage and later. Morpholino invalidation of Ci-E(z) leads to the total disappearance of both Ci-E(z) protein and its H3K27me3 mark. Ci-E(z) morphants display a severe phenotype. Strikingly, the earliest defects occur at the 4-cell stage with the dysregulation of cell positioning and mitotic impairment. At later stages, Ci-E(z)-deficient embryos are affected by terminal differentiation defects of neural, epidermal and muscle tissues, by the failure to form a notochord and by the absence of caudal nerve. These major phenotypic defects are specifically rescued by injection of a morpholino-resistant Ci-E(z) mRNA, which restores expression of Ci-E(z) protein and re-deposition of the H3K27me3 mark. As observed by qPCR analyses, Ci-E(z) invalidation leads to the early derepression of tissue-specific developmental genes, whereas late-acting developmental genes are generally down-regulated. Altogether, our results suggest that Ci-E(z) plays a major role during embryonic development in Ciona intestinalis by silencing early-acting developmental genes in a Hox-independent manner. PMID:26276097

  1. New Federal Regulations for Improving Quality in Opioid Treatment Programs

    PubMed Central

    Pelletier, Luc R.; Hoffman, Jeffrey A.

    2006-01-01

    The U.S. Food and Drug Administration (FDA) has enforced federal requirements related to the use of methadone since 1972; regulations essentially have not changed for nearly 30 years. With Congress’ recently released federal regulations for opioid treatment programs (OTPs), however, oversight of OTPs has shifted from the FDA to the Substance Abuse and Mental Health Services Administration (SAMHSA). SAMHSA’s Center for Substance Abuse Treatment developed guidelines for accreditation agencies such as the Joint Commission on Accreditation of Healthcare Organizations and The Rehabilitation Accreditation Commission…CARF to develop standards for OTPs. Preliminary findings show that OTPs are indeed able to meet these accreditation standards. This article reviews the need for the changes, the history of methadone treatment oversight, the development of accreditation requirements, stakeholders’ initial response to the proposed regulations, and performance domains of importance to OTPs. PMID:16758002

  2. Genome-wide prediction of cis-acting RNA elements regulating tissue-specific pre-mRNA alternative splicing

    PubMed Central

    Wang, Xin; Wang, Kejun; Radovich, Milan; Wang, Yue; Wang, Guohua; Feng, Weixing; Sanford, Jeremy R; Liu, Yunlong

    2009-01-01

    Background Human genes undergo various patterns of pre-mRNA splicing across different tissues. Such variation is primarily regulated by trans-acting factors that bind on exonic and intronic cis-acting RNA elements (CAEs). Here we report a computational method to mechanistically identify cis-acting RNA elements that contribute to the tissue-specific alternative splicing pattern. This method is an extension of our previous model, SplicingModeler, which predicts the significant CAEs that contribute to the splicing differences between two tissues. In this study, we introduce tissue-specific functional levels estimation step, which allows evaluating regulatory functions of predicted CAEs that are involved in more than two tissues. Results Using a publicly available Affymetrix Genechip® Human Exon Array dataset, our method identifies 652 cis-acting RNA elements (CAEs) across 11 human tissues. About one third of predicted CAEs can be mapped to the known RBP (RNA binding protein) binding sites or match with other predicted exonic splicing regulator databases. Interestingly, the vast majority of predicted CAEs are in intronic regulatory regions. A noticeable exception is that many exonic elements are found to regulate the alternative splicing between cerebellum and testes. Most identified elements are found to contribute to the alternative splicing between two tissues, while some are important in multiple tissues. This suggests that genome-wide alternative splicing patterns are regulated by a combination of tissue-specific cis-acting elements and "general elements" whose functional activities are important but differ across multiple tissues. Conclusion In this study, we present a model-based computational approach to identify potential cis-acting RNA elements by considering the exon splicing variation as the combinatorial effects of multiple cis-acting regulators. This methodology provides a novel evaluation on the functional levels of cis-acting RNA elements by estimating

  3. Audit Report on "The Department of Energy's American Recovery and Reinvestment Act -- Florida State Energy Program"

    SciTech Connect

    2010-06-01

    The Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE) provides grants to states, territories, and the District of Columbia to support their energy priorities through the State Energy Program (SEP). The SEP provides Federal financial assistance to carry out energy efficiency and renewable energy projects that meet each state's unique energy needs while also addressing national goals such as energy security. Federal funding is based on a grant formula that takes into account population and energy consumption. The SEP emphasizes the state's role as the decision maker and administrator for the program. The American Recovery and Reinvestment Act of 2009 (Recovery Act) expanded the SEP, authorizing $3.1 billion in grants. Based on existing grant formulas and after reviewing state-level plans, EERE made awards to states. The State of Florida's Energy Office (Florida) was allocated $126 million - a 90-fold increase over Florida's average annual SEP grant of $1.4 million. Per the Recovery Act, this funding must be obligated by September 30, 2010, and spent by April 30, 2012. As of March 10, 2010, Florida had expended $13.2 million of the SEP Recovery Act funds. Florida planned to use its grant funds to undertake activities that would preserve and create jobs; save energy; increase renewable energy sources; and, reduce greenhouse gas emissions. To accomplish Recovery Act objectives, states could either fund new or expand existing projects. As a condition of the awards, EERE required states to develop and implement sound internal controls over the use of Recovery Act funds. Based on the significant increase in funding from the Recovery Act, we initiated this review to determine whether Florida had internal controls in place to provide assurance that the goals of the SEP and Recovery Act will be met and accomplished efficiently and effectively. We identified weaknesses in the implementation of SEP Recovery Act projects that have adversely impacted

  4. Environmental Guidance Program Reference Book: Endangered Species Act and the Fish and Wildlife Coordination Act. Revision 5

    SciTech Connect

    Not Available

    1989-01-01

    The Endangered Species Act and the Fish and Wildlife Coordination Act are major federal statutes designed to protect plant and animal resources from adverse effects due to development projects. Both Acts require consultation with wildlife authorities prior to committing resources to certain types of projects. The purposes and requirements of the two statutes are summarized in the following subsections. Also presented is a list of contacts in the regional and field offices of the US Fish and Wildlife Service.

  5. Flavonoids act as negative regulators of auxin transport in vivo in arabidopsis

    NASA Technical Reports Server (NTRS)

    Brown, D. E.; Rashotte, A. M.; Murphy, A. S.; Normanly, J.; Tague, B. W.; Peer, W. A.; Taiz, L.; Muday, G. K.

    2001-01-01

    Polar transport of the plant hormone auxin controls many aspects of plant growth and development. A number of synthetic compounds have been shown to block the process of auxin transport by inhibition of the auxin efflux carrier complex. These synthetic auxin transport inhibitors may act by mimicking endogenous molecules. Flavonoids, a class of secondary plant metabolic compounds, have been suggested to be auxin transport inhibitors based on their in vitro activity. The hypothesis that flavonoids regulate auxin transport in vivo was tested in Arabidopsis by comparing wild-type (WT) and transparent testa (tt4) plants with a mutation in the gene encoding the first enzyme in flavonoid biosynthesis, chalcone synthase. In a comparison between tt4 and WT plants, phenotypic differences were observed, including three times as many secondary inflorescence stems, reduced plant height, decreased stem diameter, and increased secondary root development. Growth of WT Arabidopsis plants on naringenin, a biosynthetic precursor to those flavonoids with auxin transport inhibitor activity in vitro, leads to a reduction in root growth and gravitropism, similar to the effects of synthetic auxin transport inhibitors. Analyses of auxin transport in the inflorescence and hypocotyl of independent tt4 alleles indicate that auxin transport is elevated in plants with a tt4 mutation. In hypocotyls of tt4, this elevated transport is reversed when flavonoids are synthesized by growth of plants on the flavonoid precursor, naringenin. These results are consistent with a role for flavonoids as endogenous regulators of auxin transport.

  6. Progesterone acts via progesterone receptors A and B to regulate breast cancer resistance protein expression.

    PubMed

    Vore, Mary; Leggas, Markos

    2008-03-01

    The breast cancer resistance protein (BCRP; ABCG2) is an ATP-dependent efflux multidrug transporter that belongs to the G family of half-transporters that consist of six transmembrane-spanning domains and must homodimerize to form the active membrane transporter. It is expressed in the apical plasma membrane domain of the small intestine, endothelium, and liver, where it has been shown to play an important role in limiting drug absorption and distribution and in enhancing drug clearance, respectively. BCRP is also expressed in the apical membrane of mammary alveolar epithelia, where it mediates efflux of substrates into milk, and in the placental syncytiotro-phoblasts, where it reduces fetal exposure to these substrates. BCRP substrates include numerous drugs (topotecan, nitrofurantoin, cimetidine) as well as food carcinogens (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and the vitamins riboflavin and folic acid. BCRP expression is regulated by a number of nuclear transcription factors, including the peroxisome proliferator-activated receptor-gamma and Hif-1. This issue of Molecular Pharmacology includes a study (p. 845) now conclusively demonstrating that progesterone acts via the progesterone A and B receptors to regulate BCRP expression in a placental cell line.

  7. PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator

    PubMed Central

    Kim, Yoosik; Lee, Jung Hyun; Park, Jong-Eun; Cho, Jun; Yi, Hyerim; Kim, V. Narry

    2014-01-01

    dsRNA-dependent protein kinase R (PKR) is a ubiquitously expressed enzyme well known for its roles in immune response. Upon binding to viral dsRNA, PKR undergoes autophosphorylation, and the phosphorylated PKR (pPKR) regulates translation and multiple signaling pathways in infected cells. Here, we found that PKR is activated in uninfected cells, specifically during mitosis, by binding to dsRNAs formed by inverted Alu repeats (IRAlus). While PKR and IRAlu-containing RNAs are segregated in the cytosol and nucleus of interphase cells, respectively, they interact during mitosis when nuclear structure is disrupted. Once phosphorylated, PKR suppresses global translation by phosphorylating the α subunit of eukaryotic initiation factor 2 (eIF2α). In addition, pPKR acts as an upstream kinase for c-Jun N-terminal kinase and regulates the levels of multiple mitotic factors such as CYCLINS A and B and POLO-LIKE KINASE 1 and phosphorylation of HISTONE H3. Disruption of PKR activation via RNAi or expression of a transdominant-negative mutant leads to misregulation of the mitotic factors, delay in mitotic progression, and defects in cytokinesis. Our study unveils a novel function of PKR and endogenous dsRNAs as signaling molecules during the mitosis of uninfected cells. PMID:24939934

  8. PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator.

    PubMed

    Kim, Yoosik; Lee, Jung Hyun; Park, Jong-Eun; Cho, Jun; Yi, Hyerim; Kim, V Narry

    2014-06-15

    dsRNA-dependent protein kinase R (PKR) is a ubiquitously expressed enzyme well known for its roles in immune response. Upon binding to viral dsRNA, PKR undergoes autophosphorylation, and the phosphorylated PKR (pPKR) regulates translation and multiple signaling pathways in infected cells. Here, we found that PKR is activated in uninfected cells, specifically during mitosis, by binding to dsRNAs formed by inverted Alu repeats (IRAlus). While PKR and IRAlu-containing RNAs are segregated in the cytosol and nucleus of interphase cells, respectively, they interact during mitosis when nuclear structure is disrupted. Once phosphorylated, PKR suppresses global translation by phosphorylating the α subunit of eukaryotic initiation factor 2 (eIF2α). In addition, pPKR acts as an upstream kinase for c-Jun N-terminal kinase and regulates the levels of multiple mitotic factors such as cyclins A and B and Polo-like kinase 1 and phosphorylation of histone H3. Disruption of PKR activation via RNAi or expression of a transdominant-negative mutant leads to misregulation of the mitotic factors, delay in mitotic progression, and defects in cytokinesis. Our study unveils a novel function of PKR and endogenous dsRNAs as signaling molecules during the mitosis of uninfected cells.

  9. Neuropeptide Y acts in the paraventricular nucleus to suppress sympathetic nerve activity and its baroreflex regulation.

    PubMed

    Cassaglia, Priscila A; Shi, Zhigang; Li, Baoxin; Reis, Wagner L; Clute-Reinig, Nicholas M; Stern, Javier E; Brooks, Virginia L

    2014-04-01

    Neuropeptide Y (NPY), a brain neuromodulator that has been strongly implicated in the regulation of energy balance, also acts centrally to inhibit sympathetic nerve activity (SNA); however, the site and mechanism of action are unknown. In chloralose-anaesthetized female rats, nanoinjection of NPY into the paraventricular nucleus of the hypothalamus (PVN) dose-dependently suppressed lumbar SNA (LSNA) and its baroreflex regulation, and these effects were blocked by prior inhibition of NPY Y1 or Y5 receptors. Moreover, PVN injection of Y1 and Y5 receptor antagonists in otherwise untreated rats increased basal and baroreflex control of LSNA, indicating that endogenous NPY tonically inhibits PVN presympathetic neurons. The sympathoexcitation following blockade of PVN NPY inhibition was eliminated by prior PVN nanoinjection of the melanocortin 3/4 receptor inhibitor SHU9119. Moreover, presympathetic neurons, identified immunohistochemically using cholera toxin b neuronal tract tracing from the rostral ventrolateral medulla (RVLM), express NPY Y1 receptor immunoreactivity, and patch-clamp recordings revealed that both NPY and α-melanocyte-stimulating hormone (α-MSH) inhibit and stimulate, respectively, PVN-RVLM neurons. Collectively, these data suggest that PVN NPY inputs converge with α-MSH to influence presympathetic neurons. Together these results identify endogenous NPY as a novel and potent inhibitory neuromodulator within the PVN that may contribute to changes in SNA that occur in states associated with altered energy balance, such as obesity and pregnancy. PMID:24535439

  10. Flavonoids Act as Negative Regulators of Auxin Transport in Vivo in Arabidopsis1

    PubMed Central

    Brown, Dana E.; Rashotte, Aaron M.; Murphy, Angus S.; Normanly, Jennifer; Tague, Brian W.; Peer, Wendy A.; Taiz, Lincoln; Muday, Gloria K.

    2001-01-01

    Polar transport of the plant hormone auxin controls many aspects of plant growth and development. A number of synthetic compounds have been shown to block the process of auxin transport by inhibition of the auxin efflux carrier complex. These synthetic auxin transport inhibitors may act by mimicking endogenous molecules. Flavonoids, a class of secondary plant metabolic compounds, have been suggested to be auxin transport inhibitors based on their in vitro activity. The hypothesis that flavonoids regulate auxin transport in vivo was tested in Arabidopsis by comparing wild-type (WT) and transparent testa (tt4) plants with a mutation in the gene encoding the first enzyme in flavonoid biosynthesis, chalcone synthase. In a comparison between tt4 and WT plants, phenotypic differences were observed, including three times as many secondary inflorescence stems, reduced plant height, decreased stem diameter, and increased secondary root development. Growth of WT Arabidopsis plants on naringenin, a biosynthetic precursor to those flavonoids with auxin transport inhibitor activity in vitro, leads to a reduction in root growth and gravitropism, similar to the effects of synthetic auxin transport inhibitors. Analyses of auxin transport in the inflorescence and hypocotyl of independent tt4 alleles indicate that auxin transport is elevated in plants with a tt4 mutation. In hypocotyls of tt4, this elevated transport is reversed when flavonoids are synthesized by growth of plants on the flavonoid precursor, naringenin. These results are consistent with a role for flavonoids as endogenous regulators of auxin transport. PMID:11402184

  11. Decree No. 0784 of 18 April 1989 regulating, in part, Act 21 of 1982 and Act 71 of 1988.

    PubMed

    1989-01-01

    This Colombian Decree regulates certain aspects of the system of family allowances. Among other things, it provides that allowances can be granted in terms of food, clothing, school scholarships, textbooks, drugs, and other substitutes for money. Further provisions of the Decree deal with the definition of persons affiliated to the regime, booklets certifying affiliation, family service subsidies, and financing. PMID:12344547

  12. Decree No. 0784 of 18 April 1989 regulating, in part, Act 21 of 1982 and Act 71 of 1988.

    PubMed

    1989-01-01

    This Colombian Decree regulates certain aspects of the system of family allowances. Among other things, it provides that allowances can be granted in terms of food, clothing, school scholarships, textbooks, drugs, and other substitutes for money. Further provisions of the Decree deal with the definition of persons affiliated to the regime, booklets certifying affiliation, family service subsidies, and financing.

  13. Allowance trading under the Clean Air Act: Who should regulate, and when?

    SciTech Connect

    Lock, R.

    1993-07-01

    The goal of this paper is to explore how compliance with the Clean Air Act Amendments of 1990 (CAAA), especially Title IV and emission trading under it, will affect the current relationship between state and federal regulation. It is difficult, with the limited experience we have had under Title IV, to be definitive about or to be a very strong advocate of too many policy positions. What may be most helpful at this point is to identify where the difficult issues in state/federal relations might arise; and then to explore ways in which tensions might be either avoided or resolved. One anticipated conclusion is that a traditional regulatory mindset could be very destructive if applied to this new area of oversight without due sensitivity to what Congress is trying to achieve in Title IV. That concern pervaded the early legislative debates; and it persists today. Title IV presents some unique challenges to state regulators and will require some creative solutions and fresh thinking if the goals of Congress are to be realized and the full benefits that allowance trading can offer are to be reaped by electricity consumers. In the ultimate analysis, Title IV amounts to a massive internalization of the external costs imposed on society by acid rain deposition. (This places in serious question the notion of additional externality {open_quotes}adders{close_quotes} for sulfur dioxide (SO{sub 2}) and nitrous oxide (NO{sub x}) at the state level for utility supply planning purposes.) The whole point of Title IV is to give those directly charged with compliance, namely power producers, the maximum flexibility to pursue least-cost compliance solutions. Perhaps the biggest single factor in how well they do this will be how state regulators respond to their compliance and allowance trading initiatives.

  14. HIPAA Newborns' and Mothers' Health Protection Act--IRS. Notice of proposed rulemaking by cross-reference to temporary regulations.

    PubMed

    1998-10-27

    Elsewhere in this issue of the Federal Register, the IRS is issuing temporary regulations relating to minimum hospital length-of-stay requirements imposed on group health plans with respect to mothers and newborns. The hospital length-of-stay requirements were added to the Internal Revenue Code by section 1531 of the Taxpayer Relief Act of 1997. The IRS is issuing the temporary regulations at the same time that the Pension and Welfare Benefits Administration of the U.S. Department of Labor and the Health Care Financing Administration of the U.S. Department of Health and Human Services are issuing substantially similar interim final regulations relating to hospital length-of-stay requirements added by the Newborns' and Mothers' Health Protection Act of 1996 to the Employee Retirement Income Security Act of 1974 and the Public Health Service Act. The temporary regulations provide guidance to employers and group health plans relating to the new hospital length-of-stay requirements. The text of those temporary regulations also serves as the text of these proposed regulations.

  15. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling1

    PubMed Central

    Wu, Ling; Wang, Chenhui; Boisson, Bertrand; Misra, Saurav; Rayman, Patricia; Finke, James H.; Puel, Anne; Casanova, Jean-Laurent; Li, Xiaoxia

    2014-01-01

    IL-17 is a pro-inflammatory cytokine implicated in the pathogenesis of autoimmune diseases including psoriasis. ACT1 is an essential adaptor molecule in the IL-17 signaling pathway. A missense single nucleotide polymorphism (rs33980500; SNP-D10N) that resulted in the substitution of an asparagine for an aspartic acid at position 10 of ACT1 (ACT1-D10N) is associated with psoriasis susceptibility. Due to alternative splicing in humans, SNP-D10N encodes two mutated ACT1 proteins, ACT1-D10N and ACT1-D19N. Though both ACT1 isoforms are Hsp90 ‘client’ proteins, the nine additional amino acids in ACT1-D19N provide an additional Hsp90 binding site that is absent in ACT1-D10N. Therefore, while ACT1-D10N is a dead protein that is unable to transduce IL-17 signals for gene expression, ACT1-D19N is fully responsive to IL-17. Intriguingly, the two ACT1 isoforms are differentially expressed in ACT1D10N/D10N fibroblasts and T cells. Fibroblasts express both isoforms equally, enabling ACT1-D19N to compensate for the loss of ACT1-D10N function. ACT1D10N/D10N T cells, however, express predominantly ACT1-D10N. Lacking this compensatory mechanism, ACT1D10N/D10N T cells behave like ACT1-deficient T cells, exhibiting a dysregulated and hyperactive Th17 phenotype with overproduction of IL-22 and IL-17. The hyperactive Th17 response combined with fully responsive fibroblasts likely synergized to contribute to psoriasis susceptibility in SNP-D10N patients. PMID:25024377

  16. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.

    PubMed

    Wu, Ling; Wang, Chenhui; Boisson, Bertrand; Misra, Saurav; Rayman, Patricia; Finke, James H; Puel, Anne; Casanova, Jean-Laurent; Li, Xiaoxia

    2014-08-15

    IL-17 is a proinflammatory cytokine implicated in the pathogenesis of autoimmune diseases including psoriasis. ACT1 is an essential adaptor molecule in the IL-17 signaling pathway. A missense single nucleotide polymorphism (rs33980500; SNP-D10N) that resulted in the substitution of an asparagine for an aspartic acid at position 10 of ACT1 (ACT1-D10N) is associated with psoriasis susceptibility. Due to alternative splicing in humans, SNP-D10N encodes two mutated ACT1 proteins, ACT1-D10N and ACT1-D19N. Although both ACT1 isoforms are Hsp90 client proteins, the nine additional amino acids in ACT1-D19N provide an additional Hsp90 binding site that is absent in ACT1-D10N. Therefore, whereas ACT1-D10N is a dead protein that is unable to transduce IL-17 signals for gene expression, ACT1-D19N is fully responsive to IL-17. Intriguingly, the two ACT1 isoforms are differentially expressed in ACT1(D10N/D10N) fibroblasts and T cells. Fibroblasts express both isoforms equally, enabling ACT1-D19N to compensate for the loss of ACT1-D10N function. ACT1(D10N/D10N) T cells, however, express predominantly ACT1-D10N. Lacking this compensatory mechanism, ACT1(D10N/D10N) T cells behave like ACT1-deficient T cells, exhibiting a dysregulated and hyperactive Th17 phenotype with overproduction of IL-22 and IL-17. The hyperactive Th17 response combined with fully responsive fibroblasts likely synergized to contribute to psoriasis susceptibility in SNP-D10N patients. PMID:25024377

  17. Preliminary Audit Report on "Management Controls over the Commonwealth of Virginia's Efforts to Implement the American Recovery and Reinvestment Act Weatherization Assistance Program"

    SciTech Connect

    2010-05-01

    the Recovery Act; (2) Reviewed documentation supporting sub-grantee requests for reimbursements to verify the accuracy of amounts charged; (3) Periodically reconciled amounts paid to sub-grantees to the actual cost to weatherize units; (4) Maintained vehicle and equipment inventories as required by Federal regulations and state and Federal program directives; and (5) Accurately reported Weatherization Program results to the Department. Exacerbating weaknesses in DHCD's financial controls, the Department's most recent program monitoring visit to Virginia, made in 2008 before passage of the Recovery Act, did not include a required financial review. Hence, the financial control weaknesses discussed above were not detected and had not been addressed. As described in this report, these control and reporting weaknesses increase the risk that Recovery Act objectives may not be achieved and that fraud, waste or abuse can occur and not be detected in this critically important program.

  18. Some impacts of the 1990 Clean Air Act and state clean-air regulations on the fertilizer industry

    SciTech Connect

    Breed, C.E.; Kerns, O.S.

    1992-12-31

    The Clean Air Act amendments of 1990 will intensify national efforts to reduce air pollution. They will have major impacts on governmental agencies and on industrial and commercial facilities throughout the country. As with other industries, it is essential for fertilizer dealers and producers to understand how these changes to the Clean Air Act can significantly change the way they do business. This paper is proffered as an overview of ways in which the 1990 amendments to the Clean Air Act may impact the fertilizer industry. The nonattainment, toxics, and permit provisions of the amended act will be three areas of particular concern to the fertilizer industry. Implementation of the new regulatory requirements of this legislation promises to be a long and onerous process for all concerned. However, it appears that state and local regulations may have a much more profound impact on the fertilizer industry than the new Clean Air Act.

  19. Some impacts of the 1990 Clean Air Act and state clean-air regulations on the fertilizer industry

    SciTech Connect

    Breed, C.E.; Kerns, O.S.

    1992-12-01

    The Clean Air Act amendments of 1990 will intensify national efforts to reduce air pollution. They will have major impacts an governmental agencies and on industrial and commercial facilities throughout the country. As with other industries, it is essential for fertilizer dealers and producers to understand how these changes to the Clean Air Act can significantly change the way they do business. This paper is proffered as an overview of ways in which the 1990 amendments to the Clean Air Act may impact the fertilizer industry. The nonattainment, toxics, and permit provisions of the amended act will be three areas of particular concern to the fertilizer industry. Implementation of the new regulatory requirements of this legislation promises to be a long and onerous process for all concerned. However, it appears that state and local regulations may have a much more profound impact on the fertilizer industry than the new Clean Air Act.

  20. 34 CFR 359.3 - What regulations apply to this program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... RESEARCH: SPECIAL PROJECTS AND DEMONSTRATIONS FOR SPINAL CORD INJURIES General § 359.3 What regulations apply to this program? The regulations referenced in 34 CFR 350.3 apply to this program....

  1. 34 CFR 359.3 - What regulations apply to this program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... RESEARCH: SPECIAL PROJECTS AND DEMONSTRATIONS FOR SPINAL CORD INJURIES General § 359.3 What regulations apply to this program? The regulations referenced in 34 CFR 350.3 apply to this program....

  2. 34 CFR 359.3 - What regulations apply to this program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... RESEARCH: SPECIAL PROJECTS AND DEMONSTRATIONS FOR SPINAL CORD INJURIES General § 359.3 What regulations apply to this program? The regulations referenced in 34 CFR 350.3 apply to this program....

  3. 34 CFR 359.3 - What regulations apply to this program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... RESEARCH: SPECIAL PROJECTS AND DEMONSTRATIONS FOR SPINAL CORD INJURIES General § 359.3 What regulations apply to this program? The regulations referenced in 34 CFR 350.3 apply to this program....

  4. 34 CFR 359.3 - What regulations apply to this program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... RESEARCH: SPECIAL PROJECTS AND DEMONSTRATIONS FOR SPINAL CORD INJURIES General § 359.3 What regulations apply to this program? The regulations referenced in 34 CFR 350.3 apply to this program....

  5. Transcriptional programs regulated by both LEAFY and APETALA1 at the time of flower formation.

    PubMed

    Winter, Cara M; Yamaguchi, Nobutoshi; Wu, Miin-Feng; Wagner, Doris

    2015-09-01

    Two key regulators of the switch to flower formation and of flower patterning in Arabidopsis are the plant-specific helix-turn-helix transcription factor LEAFY (LFY) and the MADS box transcription factor APETALA1 (AP1). The interactions between these two transcriptional regulators are complex. AP1 is both a direct target of LFY and can act in parallel with LFY. Available genetic and molecular evidence suggests that LFY and AP1 together orchestrate the switch to flower formation and early events during flower morphogenesis by altering transcriptional programs. However, very little is known about target genes regulated by both transcription factors. Here, we performed a meta-analysis of public datasets to identify genes that are likely to be regulated by both LFY and AP1. Our analyses uncovered known and novel direct LFY and AP1 targets with a role in the control of onset of flower formation. It also identified additional families of proteins and regulatory pathways that may be under transcriptional control by both transcription factors. In particular, several of these genes are linked to response to hormones, to transport and to development. Finally, we show that the gibberellin catabolism enzyme ELA1, which was recently shown to be important for the timing of the switch to flower formation, is positively feedback-regulated by AP1. Our study contributes to the elucidation of the regulatory network that leads to formation of a vital plant organ system, the flower.

  6. Decreasing latitude and increasing regulation in transplantable tissue programs.

    PubMed

    Humphries, Linda

    2005-11-01

    ADVANCED TECHNOLOGY and improved surgical techniques have led to new therapeutic uses for allografts. DISEASE TRANSMISSION via allograft tissue transplants has prompted federal intervention in the tissue banking industry and resulted in federal regulations. NEW STANDARDS from the Joint Commission on Accreditation of Healthcare Organizations became effective July 1, 2005, and apply to all hospitals that store or implant allograft tissues. These standards include mandatory policies on all aspects of hospital transplantation programs, including tissue ordering, receipt, storage, issuance, and record keeping. PMID:16355937

  7. Environmental Guidance Program Reference Book: Comprehensive Environmentally Response, Compensation, and Liability Act

    SciTech Connect

    Not Available

    1991-12-31

    This Reference Book contains a current copy of the Comprehensive Environmental Response Compensation, and Liability Act and those regulations that implement the statute and appear to be most relevant to Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (FTS 896-2609 or Commercial 202/586-2609).

  8. Compilation of the Low-Income Home Energy Assistance Act of 1981, Native American Programs Act of 1974, Head Start Act, Follow September 30, 1985.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    This booklet compiles five Congressional Acts for use by the House Committee on Education and Labor. The "Low-Income Home Energy Assistance Act of 1981" provides for the Secretary of Health and Human Services to authorize grants to States to assist eligible households to meet the costs of home energy, up to the amount of $2,140,000,000 for 1985…

  9. 77 FR 49849 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Office of Child Support...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA/ Office of Child Support... Counsel. Notice of Computer Matching Program, SSA With the Office of Child Support Enforcement (OCSE) A... renewal of an existing computer-matching program that will expire on September 30, 2012. SUMMARY:...

  10. 78 FR 40541 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA)-Match Number 1014

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... ADMINISTRATION Privacy Act of 1974, as Amended; Computer Matching Program (SSA)--Match Number 1014 AGENCY: Social Security Administration (SSA). ] ACTION: Notice of a renewal of an existing computer matching program that... amended, this notice announces a renewal of an existing computer matching program that we are...

  11. 77 FR 39748 - Computer Matching and Privacy Protection Act of 1988; Report of Matching Program: RRB and State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Unemployment and Sickness Insurance Benefit System, which was published in the Federal Register (FR) on July 26, 2010 (75 FR 43725). 5. Inclusive Dates of the Matching Program: This computer matching program is... Computer Matching and Privacy Protection Act of 1988; Report of Matching Program: RRB and State...

  12. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75...

  13. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75...

  14. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75...

  15. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75...

  16. 34 CFR 280.3 - What regulations apply to this program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75...

  17. 75 FR 54213 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Office of Personnel Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... levels established by law and regulations. The SVB program provides special benefits to certain World War II veterans. Specific information regarding the matching programs to be conducted because of...

  18. Positive Selection within a Diatom Species Acts on Putative Protein Interactions and Transcriptional Regulation

    PubMed Central

    Koester, Julie A.; Swanson, Willie J.; Armbrust, E. Virginia

    2013-01-01

    Diatoms are the most species-rich group of microalgae, and their contribution to marine primary production is important on a global scale. Diatoms can form dense blooms through rapid asexual reproduction; mutations acquired and propagated during blooms likely provide the genetic, and thus phenotypic, variability upon which natural selection may act. Positive selection was tested using genome and transcriptome-wide pair-wise comparisons of homologs in three genera of diatoms (Pseudo-nitzschia, Ditylum, and Thalassiosira) that represent decreasing phylogenetic distances. The signal of positive selection was greatest between two strains of Thalassiosira pseudonana. Further testing among seven strains of T. pseudonana yielded 809 candidate genes of positive selection, which are 7% of the protein-coding genes. Orphan genes and genes encoding protein-binding domains and transcriptional regulators were enriched within the set of positively selected genes relative to the genome as a whole. Positively selected genes were linked to the potential selective pressures of nutrient limitation and sea surface temperature based on analysis of gene expression profiles and identification of positively selected genes in subsets of strains from locations with similar environmental conditions. The identification of positively selected genes presents an opportunity to test new hypotheses in natural populations and the laboratory that integrate selected genotypes in T. pseudonana with their associated phenotypes and selective forces. PMID:23097498

  19. Positive selection within a diatom species acts on putative protein interactions and transcriptional regulation.

    PubMed

    Koester, Julie A; Swanson, Willie J; Armbrust, E Virginia

    2013-02-01

    Diatoms are the most species-rich group of microalgae, and their contribution to marine primary production is important on a global scale. Diatoms can form dense blooms through rapid asexual reproduction; mutations acquired and propagated during blooms likely provide the genetic, and thus phenotypic, variability upon which natural selection may act. Positive selection was tested using genome and transcriptome-wide pair-wise comparisons of homologs in three genera of diatoms (Pseudo-nitzschia, Ditylum, and Thalassiosira) that represent decreasing phylogenetic distances. The signal of positive selection was greatest between two strains of Thalassiosira pseudonana. Further testing among seven strains of T. pseudonana yielded 809 candidate genes of positive selection, which are 7% of the protein-coding genes. Orphan genes and genes encoding protein-binding domains and transcriptional regulators were enriched within the set of positively selected genes relative to the genome as a whole. Positively selected genes were linked to the potential selective pressures of nutrient limitation and sea surface temperature based on analysis of gene expression profiles and identification of positively selected genes in subsets of strains from locations with similar environmental conditions. The identification of positively selected genes presents an opportunity to test new hypotheses in natural populations and the laboratory that integrate selected genotypes in T. pseudonana with their associated phenotypes and selective forces. PMID:23097498

  20. Impact of Clean Air Act Regulations on Nitrogen Fate and Transport in the Neuse River Basin

    NASA Astrophysics Data System (ADS)

    Gabriel, M. C.; Knightes, C. D.; Dennis, R. L.; Cooter, E. J.

    2012-12-01

    This study investigated impacts of Clean Air Act Amendment (CAAA) NOx emissions regulations on the fate and transport of nitrogen for two watersheds in the Neuse River Basin, North Carolina, USA from 1990 to 2020. The Soil and Water Assessment Tool (SWAT) and the Community Multi-scale Air Quality (CMAQ) modeling system were used. CMAQ simulated atmospheric chemical transport and nitrogen deposition. This data was entered into SWAT which simulated watershed hydrology and water quality. Two cases were investigated: one that incorporates CAAA regulatory emissions controls in CMAQ simulation (with) and a second case that does not (without). SWAT model results forecasted a 70% decrease in inorganic nitrogen discharge from the Little River watershed and a 50% decrease for the Nahunta watershed by 2020 under the emission control (with) scenario. Denitrification and plant nitrogen uptake played important roles in nitrogen discharge from each watershed. The nitrogen discharge response time following a change in atmospheric nitrogen deposition was 4 years for the Nahunta watershed and 2 years for the Little River watershed. The longer response time for Nahunta is primarily due to a higher percentage of soybean land cover (22.5% [Nahunta]; 1.6% [Little River]). Agricultural land covers had varied nitrogen response times to changes in atmospheric deposition, particularly for soybean, hay and corn. The studied watersheds retained >80% of all nitrogen delivered by agriculture fertilization, biological fixation and atmospheric deposition.

  1. 34 CFR 655.1 - Which programs do these regulations govern?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false Which programs do these regulations govern? 655.1 Section 655.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... § 655.1 Which programs do these regulations govern? The regulations in this part govern...

  2. 34 CFR 655.1 - Which programs do these regulations govern?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false Which programs do these regulations govern? 655.1 Section 655.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... § 655.1 Which programs do these regulations govern? The regulations in this part govern...

  3. 34 CFR 655.1 - Which programs do these regulations govern?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false Which programs do these regulations govern? 655.1 Section 655.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... § 655.1 Which programs do these regulations govern? The regulations in this part govern...

  4. 34 CFR 655.1 - Which programs do these regulations govern?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Which programs do these regulations govern? 655.1 Section 655.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... § 655.1 Which programs do these regulations govern? The regulations in this part govern...

  5. 78 FR 79729 - Integrated Mortgage Disclosures Under the Real Estate Settlement Procedures Act (Regulation X...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...Sections 1098 and 1100A of the Dodd-Frank Wall Street Reform and Consumer Protection Act (Dodd-Frank Act) direct the Bureau to publish rules and forms that combine certain disclosures that consumers receive in connection with applying for and closing on a mortgage loan under the Truth in Lending Act and the Real Estate Settlement Procedures Act. Consistent with this requirement, the Bureau is......

  6. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES... objective intent; (3) The manufacture of the HCT/P does not involve the combination of the cells or tissues... not have a systemic effect and is not dependent upon the metabolic activity of living cells for...

  7. 21 CFR 1271.10 - Are my HCT/P's regulated solely under section 361 of the PHS Act and the regulations in this part...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES... objective intent; (3) The manufacture of the HCT/P does not involve the combination of the cells or tissues... not have a systemic effect and is not dependent upon the metabolic activity of living cells for...

  8. 78 FR 4725 - Escrow Requirements Under the Truth in Lending Act (Regulation Z)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... persons excluded from coverage by section 1029 of the Dodd-Frank Act). See 76 FR 79768 (Dec. 22, 2011... granted to the Board by the Home Ownership and Equity Protection Act of 1994 (HOEPA). See 73 FR 44522... of sections 1461 and 1462 of the Dodd-Frank Act. 76 FR 11598 (Mar. 2, 2011) (the Board's 2011...

  9. Ryan White CARE Act Title IV programs: a preliminary characterization of benefits and costs.

    PubMed

    Abramowitz, Susan; Greene, Danielle

    2005-01-01

    Congress enacted the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act in 1990 to address the unmet health needs of persons living with HIV (PLWH) by funding primary healthcare and support services to enhance access to and retention in care. The CARE Act was amended and reauthorized in 1996 and in 2000, and again in December 2006. As originally enacted, the CARE Act was a compromise across a wide political divide. A structure was established that distributed Ryan White CARE Act (RWCA) funds through five federal titles, with different parameters set for each title. Some funds were placed under federal control, while others were controlled locally and distributed to cities and states. Some funds were earmarked for specific services or populations, such as medications; others could be assigned according to a community's priorities. Title IV, the section of the RWCA dedicated to serving women, children, youth, and families who are infected with and affected by HIV/AIDS, is unique, even given the diversity of the other titles. The Title IV program was first implemented in 1988 as the Pediatric AIDS Demonstration Program. It became part of the CARE Act in 1994, and its purpose was expanded at that time to create better links between medical and support services. Although it is the smallest of the titles, with less than 4 percent of the RWCA budget, it may have the broadest mission: providing medical, logistical, psychosocial, and developmental care not just to persons living with the virus, but to entire families. In addition to its focus on this target population, Title IV is unique in its recognition of the need for, and historic support of, comprehensive systems of care to improve, expand, and coordinate service delivery, HIV-prevention efforts, and clinical research. Title IV was excluded from a 10 percent administrative cap on administrative expenses, which enables its funded programs to accomplish this mission. As of 2003, Title IV supported 74 family

  10. 78 FR 60381 - Amendments to the 2013 Mortgage Rules Under the Equal Credit Opportunity Act (Regulation B), Real...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... February 15, 2013, at 78 FR 11280. FOR FURTHER INFORMATION CONTACT: Whitney Patross, Attorney; Richard... Under the Truth in Lending Act (Regulation Z), 78 FR 4726 (Jan. 22, 2013) (2013 Escrows Final Rule...), 78 FR 6856 (Jan. 31, 2013) (2013 HOEPA Final Rule), and Ability-to-Repay and Qualified...

  11. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false States designated under paragraph 301(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... DESIGNATED STATES AND TERRITORIES; AND FOR DESIGNATION OF ESTABLISHMENTS WHICH ENDANGER PUBLIC HEALTH AND...

  12. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false States designated under paragraph 5(c) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... Designating Establishments With Operations Which Would Clearly Endanger the Public Health; Disposition...

  13. 76 FR 28966 - Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Revisions to Oil Pipeline Regulations Pursuant to the Energy Policy Act of 1992; Notice of Annual Change in the Producer Price Index for Finished Goods The...

  14. 29 CFR 102.117 - Freedom of Information Act Regulations: Board materials and formal documents available for public...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., the cost of conducting computer searches for information and for providing information in electronic... 29 Labor 2 2010-07-01 2010-07-01 false Freedom of Information Act Regulations: Board materials and... for response; appeal from denial of request; fees for document search and duplication; files...

  15. 77 FR 33635 - Amendment to the Bank Secrecy Act Regulations-Requirement That Clerks of Court Report Certain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ...\\ 66 FR 67680 (December 31, 2001), codified at 31 CFR 1010.330. \\7\\ 26 CFR 1.6050I-1. As amended... Financial Crimes Enforcement Network 31 CFR Part 1010 RIN 1506-AB17 Amendment to the Bank Secrecy Act Regulations--Requirement That Clerks of Court Report Certain Currency Transactions AGENCY: Financial...

  16. 78 FR 63408 - Petition To Amend Animal Welfare Act Regulations To Prohibit Public Contact With Big Cats, Bears...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... 5, 2013 (78 FR 47215) is reopened. We will consider all comments that we receive on or before.... SUPPLEMENTARY INFORMATION: On August 5, 2013, we published in the Federal Register (78 FR 47215-47217, Docket No... Animal Welfare Act Regulations To Prohibit Public Contact With Big Cats, Bears, and Nonhuman...

  17. 78 FR 23171 - Amendments to the 2013 Escrows Final Rule Under the Truth in Lending Act (Regulation Z)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... loans made in ``rural'' or ``underserved'' areas. \\1\\ 78 FR 4726 (Jan. 22, 2013). \\2\\ The other rules...) (2013 ATR Final Rule), 78 FR 6407; High-Cost Mortgages and Homeownership Counseling Amendments to the... Settlement Procedures Act (Regulation X) (2013 HOEPA Final Rule), 78 FR 6855; Disclosure and...

  18. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false States designated under paragraph 5(c) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... Designating Establishments With Operations Which Would Clearly Endanger the Public Health; Disposition...

  19. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... circuit supervisor (showing any modifications required by the circuit supervisor) to the Labels and Packaging Staff, Meat and Poultry Inspection, Food Safety and Inspection Service, USDA, Washington, DC...

  20. 9 CFR 381.222 - States designated under paragraph 5(c) of the Act; application of regulations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) of the Act; application of regulations. 381.222 Section 381.222 Animals and Animal Products FOOD... modifications required by the Circuit Supervisor) to the Labels and Packaging Staff, Meat and Poultry Inspection Food Safety and Inspection Service, U.S. Department of Agriculture, Washington, DC 20250,...

  1. 9 CFR 331.3 - States designated under paragraph 301(c) of the Act; application of regulations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...(c) of the Act; application of regulations. 331.3 Section 331.3 Animals and Animal Products FOOD... circuit supervisor (showing any modifications required by the circuit supervisor) to the Labels and Packaging Staff, Meat and Poultry Inspection, Food Safety and Inspection Service, USDA, Washington, DC...

  2. Application of TALEs, CRISPR/Cas and sRNAs as trans-acting regulators in prokaryotes.

    PubMed

    Copeland, Matthew F; Politz, Mark C; Pfleger, Brian F

    2014-10-01

    The last several years have witnessed an explosion in the understanding and use of novel, versatile trans-acting elements. TALEs, CRISPR/Cas, and sRNAs can be easily fashioned to bind any specific sequence of DNA (TALEs, CRISPR/Cas) or RNA (sRNAs) because of the simple rules governing their interactions with nucleic acids. This unique property enables these tools to repress the expression of genes at the transcriptional or post-transcriptional levels, respectively, without prior manipulation of cis-acting and/or chromosomal target DNA sequences. These tools are now being harnessed by synthetic biologists, particularly those in the eukaryotic community, for genome-wide regulation, editing, or epigenetic studies. Here we discuss the exciting opportunities for using TALEs, CRISPR/Cas, and sRNAs as synthetic trans-acting regulators in prokaryotes.

  3. Development of Stitched, Braided and Woven Composite Structures in the ACT Program and at Langley Research Center

    NASA Technical Reports Server (NTRS)

    Dow, Marvin B.; Dexter, H. Benson

    1997-01-01

    Summary results are presented from the research conducted on woven, braided, knitted and stitched (textile) composites at the Langley Research Center and under the NASA Advanced Composites Technology (ACT) Program in the period from 1985 to 1997. The report also includes an annotated bibliography of 270 U.S. publications on textile composites (with their abstracts). Two major research areas are discussed: (1) the general research in textile composites performed throughout the period under the direction of the Langley Research Center and (2) the development of textile composite aircraft structures by industry under the NASA ACT Program. The annotated bibliography is organized in three subsections: (1) general textiles R&D under the auspices of Langley, (2) ACT Program development of textile structural components, and (3) textiles research by individuals and organizations not associated with the ACT Program. An author index is provided for the reports and documents.

  4. Employee Retirement Income Security Act of 1974: rules and regulations for administration and enforcement; claims procedure. Pension and Welfare Benefits Administration, Labor. Final regulation.

    PubMed

    2000-11-21

    This document contains a final regulation revising the minimum requirements for benefit claims procedures of employee benefit plans covered by Title I of the Employee Retirement Income Security Act of 1974 (ERISA or the Act). The regulation establishes new standards for the processing of claims under group health plans and plans providing disability benefits and further clarifies existing standards for all other employee benefit plans. The new standards are intended to ensure more timely benefit determinations, to improve access to information on which a benefit determination is made, and to assure that participants and beneficiaries will be afforded a full and fair review of denied claims. When effective, the regulation will affect participants and beneficiaries of employee benefit plans, employers who sponsor employee benefit plans, plan fiduciaries, and others who assist in the provision of plan benefits, such as third-party benefits administrators and health service providers or health maintenance organizations that provide benefits to participants and beneficiaries of employee benefit plans.

  5. Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10). Environmental Guidance Program Reference Book, Revision 4

    SciTech Connect

    1992-03-01

    This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609).

  6. 75 FR 55791 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-14

    ... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for Alliant Energy--WPL Edgewater Generating Station AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of final order on petition to object to Clean Air Act operating permit. SUMMARY: This...

  7. 77 FR 59186 - Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ..., 2011, and submitted by the Environmental Integrity Project and the Southern Alliance for Clean Energy... AGENCY Clean Air Act Operating Permit Program; Petition for Objection to State Operating Permit for...: Pursuant to Clean Air Act (CAA) Section 505(b)(2), the EPA Administrator signed an Order, dated August...

  8. 76 FR 53452 - Clean Air Act Operating Permit Program; Response to Petition To Reopen the 2001 Title V Permit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... AGENCY Clean Air Act Operating Permit Program; Response to Petition To Reopen the 2001 Title V Permit for.... ] SUMMARY: Pursuant to the Clean Air Act (CAA), the Director of the EPA Region III Air Protection Division... Reliant Energy Mid-Atlantic Power Holdings, LLC, for its Portland Generating Station in Northampton...

  9. 78 FR 54875 - Privacy Act of 1974; Computer Matching Program Between the Department of Education (ED) and the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... Privacy Act of 1974; Computer Matching Program Between the Department of Education (ED) and the Social Security Administration (SSA) AGENCY: Department of Education. ACTION: Notice. SUMMARY: Pursuant to the Computer Matching and Privacy Protection Act of 1988, the Computer Matching and Privacy...

  10. Recovery Act Education Programs: Funding Retained Teachers, but Education Could More Consistently Communicate Stabilization Monitoring Issues. Report to Congress. GAO-11-804

    ERIC Educational Resources Information Center

    Scott, George A.

    2011-01-01

    The American Recovery and Reinvestment Act of 2009 (Recovery Act) provided $70.3 billion for three education programs--the State Fiscal Stabilization Fund (SFSF); Title I, Part A of the Elementary and Secondary Education Act (Title I); and Individuals with Disabilities Education Act (IDEA), Part B. One goal of the Recovery Act was to save and…

  11. Developing a state wellhead protection program: a user's guide to assist state agencies under the Safe Drinking Water Act

    SciTech Connect

    Roy, S.

    1988-07-01

    The 1986 Amendments to the Safe Drinking Water Act established a new Wellhead Protection (WHP) Program to protect ground water that supplies drinking water wells from sources of contamination. Under Section 1428 of the Act, each State must prepare a WHP program and submit it to EPA by June 19, 1989. Although the law requires that every State WHP program must contain specific elements, EPA recognizes that States should be allowed flexibility to tailor program details to best suit their individual needs. The document provides an overview of the major program requirements, presents major messages that a State should consider while developing a WHP program, and presents case-study examples to illustrate how a State might address each element of its WHP program.

  12. GABAA receptor-acting neurosteroids: A role in the development and regulation of the stress response

    PubMed Central

    Gunn, Benjamin G.; Cunningham, Linda; Mitchell, Scott G.; Swinny, Jerome D.; Lambert, Jeremy J.; Belelli, Delia

    2015-01-01

    Regulation of hypothalamic–pituitary–adrenocortical (HPA) axis activity by stress is a fundamental survival mechanism and HPA-dysfunction is implicated in psychiatric disorders. Adverse early life experiences, e.g. poor maternal care, negatively influence brain development and programs an abnormal stress response by encoding long-lasting molecular changes, which may extend to the next generation. How HPA-dysfunction leads to the development of affective disorders is complex, but may involve GABAA receptors (GABAARs), as they curtail stress-induced HPA axis activation. Of particular interest are endogenous neurosteroids that potently modulate the function of GABAARs and exhibit stress-protective properties. Importantly, neurosteroid levels rise rapidly during acute stress, are perturbed in chronic stress and are implicated in the behavioural changes associated with early-life adversity. We will appraise how GABAAR-active neurosteroids may impact on HPA axis development and the orchestration of the stress-evoked response. The significance of these actions will be discussed in the context of stress-associated mood disorders. PMID:24929099

  13. 75 FR 12377 - Native American Graves Protection and Repatriation Act Regulations-Disposition of Culturally...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... first rules to implement the Act on December 4, 1995 (43 CFR part 10, 60 FR 62158). --We published rules for assessing civil penalties under the Act on April 3, 2003 (43 CFR 10.12, 68 FR 16354). --We....13, 72 FR 13189). --We are publishing this rule today. --We are developing additional rules to...

  14. 75 FR 38684 - Federal Acquisition Regulation; FAR Case 2010-008, Recovery Act Subcontract Reporting Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... (DoD), General Services Administration (GSA), and National Aeronautics and Space Administration (NASA... 2009-009 in the Federal Register, (74 FR 14639) as an interim rule amending the FAR to implement section 1512 of the Recovery Act, which requires contractors to report on their use of Recovery Act...

  15. 75 FR 46859 - Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... addition, Section 3 of the Lacey Act, as amended, makes it unlawful, beginning December 15, 2008, to import... is being phased in, as described in two notices we published in the Federal Register (74 FR 5911-5913 and 74 FR 45415- 45418, Docket No. APHIS-2008-0119). Under the Act, ``Plant'' means: ``Any wild...

  16. Clean Air Act Title III accidental emission release risk management program, and how it applies to landfills

    SciTech Connect

    Hibbard, C.S.

    1999-07-01

    On June 20, 1996, EPA promulgated regulations pursuant to Title III of the Clean Air Act (CAA) Amendments of 1990 (Section 112(r)(7) of the CAA). The rule, contained in 40 CFR Part 68, is called Accidental Release Prevention Requirements: Risk Management Programs, and is intended to improve accident prevention and emergency response practices at facilities that store and/or use hazardous substances. Methane is a designated highly hazardous chemical (HHC) under the rule. The rule applies to facilities that have 10,000 pounds of methane or more in any process, roughly equivalent to about 244,000 cubic feet of methane. The US EPA has interpreted this threshold quantity as applying to landfill gas within landfills. This paper presents an overview of the Accidental Release Prevention regulations, and how landfills are affected by the requirements. This paper describes methodologies for calculating the threshold quantity of landfill gas in a landfill. Methane is in landfill gas as a mixture. Because landfill gas can burn readily, down to concentrations of about five percent methane, the entire landfill gas mixture must be treated as the regulated substance, and counts toward the 10,000-pound threshold. It is reasonable to assume that the entire landfill gas collection system, active or passive, is filled with landfill gas, and that a calculation of the volume of the system would be a calculation of the landfill gas present in the process on the site. However, the US EPA has indicated that there are some instances in which pore space gas should be included in this calculation. This paper presents methods available to calculate the amount of pore space gas in a landfill, and how to determine how much of that gas might be available for an explosion. The paper goes through how to conduct the release assessment to determine the worst-case hazard zone around the landfill.

  17. 77 FR 24757 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ...In accordance with the provisions of the Privacy Act, as amended, this notice announces a new computer matching program that we will conduct with DOL. Also published today in a separate notice in the Federal Register you will find an announcement of a renewal of an existing computer matching program (Match...

  18. 77 FR 24756 - Privacy Act of 1974, as Amended; Computer Matching Program (SSA/Department of Labor (DOL))-Match...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ...In accordance with the provisions of the Privacy Act, as amended, this notice announces a renewal of an existing computer matching program that we are currently conducting with DOL. Also published today in a separate notice in the Federal Register, you will find an announcement of a new computer matching program (Match...

  19. 75 FR 77607 - Privacy Act of 1974; Proposed New System of Records; Veterinary Medicine Loan Repayment Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Office of the Secretary Privacy Act of 1974; Proposed New System of Records; Veterinary Medicine Loan Repayment Program AGENCY: National Institute of Food and Agriculture, USDA. ACTION: Notice of a proposed new...), establishing a new Veterinary Medicine Loan Repayment Program (7 U.S.C. 3151a) which authorizes the...

  20. Summer Academic Skills Enhancement Program 1991. Private Industry Council of Franklin County Job Training Partnership Act. Final Evaluation Report.

    ERIC Educational Resources Information Center

    Donaldson, William S.

    The Summer Academic Skills Enhancement Program was funded by the Private Industry Council (PIC) of Franklin County (Ohio) through the Job Training Partnership Act (JTPA) to provide JTPA clients with the reading comprehension and language mechanics skills required for employment in entry-level positions. The program was coordinated by the…

  1. Metropolitan Housing Desegregation: The Case for an Affirmative Program under Title VI of the Civil Rights Act of 1964.

    ERIC Educational Resources Information Center

    Levin, Arthur, J.; Silard, John

    A 1966 document reviews a number of issues about housing segregation, which are related to Title IV of the Civil Rights Act of 1964. Discussed in five sections are the displacement impact of major Federal construction programs, Federal assistance to private housing, metropolitan housing desegregation, affirmative programs for desegregation, and…

  2. The ACT College Outcome Measurement Project: A New Tool for Summative Evaluation of Nontraditional Postsecondary Education Programs?

    ERIC Educational Resources Information Center

    Ward, Eric F.; Pringle, Robert A.

    The American College Testing Program (ACT) developed tests as a result of the College Outcome Measures Project (COMP). These instruments were intended for evaluation of nontraditional and traditional postsecondary education programs. They measure skills rather than information. The study was designed to check on several aspects of use of the COMP…

  3. 78 FR 73195 - Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... HUMAN SERVICES Centers for Medicare & Medicaid Services Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching Program Match No. 1312 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer...

  4. 75 FR 39575 - Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of Housing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... URBAN DEVELOPMENT Privacy Act of 1974; Notice of a Computer Matching Program Between the Department of Housing and Urban Development (HUD) and the United States Department of Agriculture (USDA) AGENCY: Office... Budget (OMB) Guidelines on the Conduct of Matching Programs (June 19, 1989, 54 FR 25818), and...

  5. An Evaluation of Public School Participation in Comprehensive Employment and Training Act (CETA) Youth Programs in Utah's Bear River District.

    ERIC Educational Resources Information Center

    Lindholm, Michael; Jones, Roger C.

    This study evaluated the effectiveness of school district participation in CETA (Comprehensive Employment and Training Act) youth programs in Box Elder and Cache Counties, Utah, as well as the overall effectiveness of CETA youth programs administered by the Bear River Association of Governments. For three years, the Bear River Association of…

  6. 76 FR 579 - Privacy Act of 1974; Computer Matching Program Between the Department of Housing and Urban...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... program between HUD and HHS was previously published at 73 FR 10046 on February 25, 2008). The first HUD... FR 68924, on December 29, 2009. Section 217 of the Consolidated Appropriations Act of 2004 (Pub. L...--Amendments; Final rule published at 74 FR 68924 on December 29, 2009, requires program administrators to...

  7. Youth Programs and the Job Training Partnership Act. Developing Competency Standards: A Guide for Private Industry Council Members.

    ERIC Educational Resources Information Center

    Strumpf, Lori

    This guide is intended to assist Private Industry Council (PIC) members in developing competency standards for youth programs receiving Job Training Partnership Act (JTPA) funds. Discussed first are the benefits of competency standards to PICs and service delivery areas (SDAs). The various components of program standards (types of skills, skill…

  8. 75 FR 37456 - Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of... Lists the Following Information Title of Proposal: Green Retrofit Program of Title XII of the...

  9. 78 FR 3474 - Privacy Act of 1974; Computer Matching Program Between the Office Of Personnel Management and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... MANAGEMENT Privacy Act of 1974; Computer Matching Program Between the Office Of Personnel Management and Social Security Administration AGENCY: Office of Personnel Management (OPM). AGENCY: Notice-computer... Management (OPM) is publishing notice of its new computer matching program with the Social...

  10. 20 CFR 668.870 - What is “program income” and how is it regulated in the INA program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... regulated in the INA program? (a) Program income is defined and regulated by WIA section 195(7), 20 CFR 667.200(a)(5) and the applicable rules in 29 CFR parts 95 and 97. (b) For grants made under this...

  11. Older Americans Act Nutrition Programs: A Community-Based Nutrition Program Helping Older Adults Remain at Home.

    PubMed

    Lloyd, Jean L; Wellman, Nancy S

    2015-01-01

    Nutrition interventions are important as the older population, most of whom live in the community, increases in size and diversity. They are key to leading a healthy, functional life and mitigating chronic health conditions. The Older Americans Act Nutrition Program served 86.3 million congregate and 137.4 million home-delivered meals to 1.6 million and 850,000 older adults, respectively (2012). Congregate and home-delivered participants were older, poorer, sicker, more functionally impaired, and at a greater risk of institutionalization than the general U.S. older population. The Nutrition Program is publically and privately funded. About 44% of congregate and 30% of home-delivered expenditures are from federal sources, which dropped from $25 per older adult in 1990 to $12 in 2013. Despite multiple funding sources, funding is insufficient for the expanding older population. Health, nutrition, and social service professionals need to coordinate their community-based services to truly help older adults remain in their homes.

  12. 75 FR 60263 - Federal Acquisition Regulation; Offering a Construction Requirement-8(a) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Federal Acquisition Regulation; Offering a Construction Requirement--8(a) Program AGENCIES: Department of... Regulations Council (Councils) are issuing a final rule amending the Federal Acquisition Regulation (FAR) to revise FAR subpart 19.8, Contracting with the Small Business Administration (The 8(a) Program),...

  13. Cis elements and trans-acting factors affecting regulation of a nonphotosynthetic light-regulated gene for chloroplast glutamine synthetase.

    PubMed Central

    Tjaden, G; Edwards, J W; Coruzzi, G M

    1995-01-01

    The glutamine synthetase (GS) gene family in pea (Pisum sativum) consists of four nuclear genes encoding distinct isoenzymes. Molecular studies have show that the GS2 gene encoding chloroplast-localized GS is expected in specific cell types and is regulated by diverse factors such as light and photorespiration. Here, we present the nucleotide sequence of the pea GS2 gene promoter. To identify the elements involved in regulation of GS2 expression, GS2 promoter-deletion analyses were performed using GS2-GUS fusions in tobacco (Nicotiana tabacum). This analysis revealed that the GS2 transit peptide is not required for mesophyll cell-specific expression of beta-glucuronidase (GUS). GUS activity was induced 2- to 4-fold in light-grown versus etiolated T1 seedlings. However, high levels of GUS activity were observed in etiolated seedlings. This observation demonstrated that regulation of expression of GS2, a nonphotosynthetic light-regulated gene, involves additional factors. A 323-bp GS2 promoter sequence is sufficient to confer light regulation to the GUS reporter gene in leaves of mature transgenic tobacco. Light-regulated expression of this pea gene promoter is observed in both tobacco and Arabidopsis, suggesting that the regulatory elements are conserved. Gel-shift analysis detected DNA-protein complexes formed with potential transcription elements within this short, light-responsive GS2 promoter fragment. PMID:7630938

  14. 25 CFR 101.10 - Federal Reserve Regulation Z and Fair Credit Reporting Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... subject to the provisions of Federal Reserve Regulation Z (Truth In Lending, 12 CFR part 226; Pub. L. 91... 25 Indians 1 2011-04-01 2011-04-01 false Federal Reserve Regulation Z and Fair Credit Reporting... ACTIVITIES LOANS TO INDIANS FROM THE REVOLVING LOAN FUND § 101.10 Federal Reserve Regulation Z and...

  15. 25 CFR 101.10 - Federal Reserve Regulation Z and Fair Credit Reporting Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... subject to the provisions of Federal Reserve Regulation Z (Truth In Lending, 12 CFR part 226; Pub. L. 91... 25 Indians 1 2010-04-01 2010-04-01 false Federal Reserve Regulation Z and Fair Credit Reporting... ACTIVITIES LOANS TO INDIANS FROM THE REVOLVING LOAN FUND § 101.10 Federal Reserve Regulation Z and...

  16. GP Supervisors' Experience in Supporting Self-Regulated Learning: A Balancing Act

    ERIC Educational Resources Information Center

    Sagasser, Margaretha H.; Kramer, Anneke W. M.; van Weel, Chris; van der Vleuten, Cees P. M.

    2015-01-01

    Self-regulated learning is essential for professional development and lifelong learning. As self-regulated learning has many inaccuracies, the need to support self-regulated learning has been recommended. Supervisors can provide such support. In a prior study trainees reported on the variation in received supervisor support. This study aims at…

  17. 34 CFR 692.51 - What other regulations apply to the SLEAP Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What other regulations apply to the SLEAP Program? 692.51 Section 692.51 Education Regulations of the Offices of the Department of Education (Continued... PROGRAM Special Leveraging Educational Assistance Partnership Program General § 692.51 What...

  18. Foundations for the Future of Alberta's Metis Settlements. Report of the MacEwan Joint Metis-Government Committee to Review the Metis Betterment Act and Regulations.

    ERIC Educational Resources Information Center

    Alberta Ministry of Municipal Affairs, Edmonton.

    Prepared as a working document for officials of the Alberta (Canada) government, this report reviews the Metis Betterment Act and regulations made under the Act with one goal being to ensure that any proposals for a new Act would place the major responsibility for the political, social, economic, and cultural development of the settlements firmly…

  19. 25 CFR 309.1 - How do the regulations in this part carry out the Indian Arts and Crafts Act of 1990?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Arts and Crafts Act of 1990? 309.1 Section 309.1 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR PROTECTION OF INDIAN ARTS AND CRAFTS PRODUCTS § 309.1 How do the regulations in this part carry out the Indian Arts and Crafts Act of 1990? These regulations define the nature and Indian...

  20. A Safety and Health Guide for Vocational Educators. Incorporating Requirements of the Occupational Safety and Health Act of 1970, Relevant Pennsylvania Requirements with Particular Emphasis for Those Concerned with Cooperative Education and Work Study Programs. Volume 15. Number 1.

    ERIC Educational Resources Information Center

    Wahl, Ray

    Intended as a guide for vocational educators to incorporate the requirements of the Occupational Safety and Health Act (1970) and the requirements of various Pennsylvania safety and health regulations with their cooperative vocational programs, the first chapter of this document presents the legal implications of these safety and health…

  1. DAY NEUTRAL FLOWERING does not act through GIGANTEA and FKF1 to regulate CONSTANS expression and flowering time.

    PubMed

    Morris, Karl; Jackson, Stephen P

    2010-09-01

    The regulation of CONSTANS (CO) gene expression and protein levels is the critical factor in determining a plant's response to photoperiod, flowering is induced when high levels of CO protein are present in the light. The regulation of CO transcription is mediated in part by GIGANTEA (GI), FKF1 and the CYCLING DOF FACTORS (CDFs) and factors affecting the levels of these proteins will also affect CO expression. The DAY NEUTRAL FLOWERING (DNF) protein is an E3 ligase involved in repressing CO expression in the early part of the day. In this article we present evidence to support the argument that DNF is not acting through the GI/FKF1/CDF regulatory mechanism to repress CO expression, but that it acts on another transcriptional activator of CO.

  2. Drinking water regulations under the Safe Drinking Water Act. Fact sheet

    SciTech Connect

    Not Available

    1990-12-01

    The fact sheet describes the requirements covered under the 1986 amendments to the Safe Drinking Water Act. Levels of various contaminants (including radio nuclides) are explained. Also discussed are the Surface Water Treatment Rule and the Total Coliforms Rule.

  3. 78 FR 28643 - Program Year (PY) 2013 Workforce Investment Act (WIA) Allotments; PY 2013 Wagner-Peyser Act Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... the Federal Register at 65 FR 8236 (February 17, 2000) which included both the rationale for the...-the-board rescission of 0.2 percent to all Federal Fiscal Year (FY) 2013 discretionary program funding... provided for consolidation of WIA Title I funding, for the Marshall Islands and Micronesia...

  4. 20 CFR 668.870 - What is “program income” and how is it regulated in the INA program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... regulated in the INA program? (a) Program income is defined and regulated by WIA section 195(7), 20 CFR 667.200(a)(5) and the applicable rules in 29 CFR parts 95 and 97. (b) For grants made under this part... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false What is âprogram incomeâ and how is...

  5. Ligand recognition by ActR, a TetR-like regulator of actinorhodin export.

    PubMed

    Tahlan, Kapil; Yu, Zhou; Xu, Ye; Davidson, Alan R; Nodwell, Justin R

    2008-11-21

    TetR-like transcriptional repressors interact with small-molecule ligands to control many facets of prokaryotic biology, including clinical antibiotic resistance. ActR is a TetR-like protein encoded in the biosynthetic gene cluster for the antibiotic actinorhodin and controls the expression of two actinorhodin exporters. We showed previously that actinorhodin and its precursor 4-dihydro-9-hydroxy-1-methyl-10-oxo-3-H-naphtho-[2,3-c]-pyran-3-(S)-acetic acid can bind ActR and prevent its interaction with DNA. Here, we compare ActR's interaction with naturally occurring and synthetic molecules to show that pathway intermediates bind to ActR 5- to 10-fold more tightly than actinorhodin itself, consistent with our suggestion that they are the biologically relevant triggers for actinorhodin export. We also find that the ligand-binding cavity of this protein can accommodate a surprisingly large diversity of ligands, many of which can release ActR from DNA in vitro and in vivo. These data suggest that the actR locus could be activated by, and perhaps adapted to confer resistance to other antibiotics.

  6. Nondiscrimination on the Basis of Handicap in Programs or Activities Receiving Federal Financial Assistance. Title 34, Code of Federal Regulations, Part 104.

    ERIC Educational Resources Information Center

    Office for Civil Rights (ED), Washington, DC.

    This document presents the final regulations of the Office for Civil Rights, Department of Education, concerning nondiscrimination on the basis of handicap in programs or activities receiving federal financial assistance under Section 504 of the Rehabilitation Act of 1973. The first part covers general provisions such as purpose, application,…

  7. NTS American Indian Religious Freedom Act Compliance Program complying with AIRFA: A literature review and evaluation

    SciTech Connect

    Pippin, L.C.

    1991-09-01

    The First Amendment to the United States Constitution guarantees the inherent right of all Americans to freedom of religion. However, since the religious practices of Native Americans are significantly different from those of the majority of Americans, their religious freedom has often restricted. Section 2 of the American Indian Religious Freedom Act (AIRFA) of 1978 (Public Law 95-341) directs federal agencies to consult with Native Americans to determine appropriate procedures to protect the inherent rights of Native Americans to believe, express, and exercise their traditional religions including, but not limited to access to sites, use and possession of sacred objects, and freedom to worship through ceremonials and traditional rites. The NTS AIRFA Compliance Program was initiated in October 1989 to assist DOE in expanding its compliance with AIRFA to incorporate all weapons testing activities on the NTS. It is directed at the development and implementation of a consultation plan designed to solicit, on behalf of DOE, Native American comments regarding the effects of the DOE's nuclear testing activities on historic properties of Native American origin and the expression and exercise of traditional Native American religions. The program has been developed around a phased approach that includes; (1) literature review and evaluation, (2) preparation of a baseline document, (3) preparation of a study design, (4) consultation with Native Americans, (5) preparation of a draft report, (6) Native American and State consultation and review, and (7) preparation of a final report.

  8. NTS American Indian Religious Freedom Act Compliance Program complying with AIRFA: A literature review and evaluation

    SciTech Connect

    Pippin, L.C.

    1991-09-01

    The First Amendment to the United States Constitution guarantees the inherent right of all Americans to freedom of religion. However, since the religious practices of Native Americans are significantly different from those of the majority of Americans, their religious freedom has often restricted. Section 2 of the American Indian Religious Freedom Act (AIRFA) of 1978 (Public Law 95-341) directs federal agencies to consult with Native Americans to determine appropriate procedures to protect the inherent rights of Native Americans to believe, express, and exercise their traditional religions including, but not limited to access to sites, use and possession of sacred objects, and freedom to worship through ceremonials and traditional rites. The NTS AIRFA Compliance Program was initiated in October 1989 to assist DOE in expanding its compliance with AIRFA to incorporate all weapons testing activities on the NTS. It is directed at the development and implementation of a consultation plan designed to solicit, on behalf of DOE, Native American comments regarding the effects of the DOE`s nuclear testing activities on historic properties of Native American origin and the expression and exercise of traditional Native American religions. The program has been developed around a phased approach that includes; (1) literature review and evaluation, (2) preparation of a baseline document, (3) preparation of a study design, (4) consultation with Native Americans, (5) preparation of a draft report, (6) Native American and State consultation and review, and (7) preparation of a final report.

  9. Pacific Northwest National Laboratory National Environmental Policy Act Compliance Program -- FY 2010 Annual Report

    SciTech Connect

    Weeks, Regan S.

    2011-04-20

    During fiscal year (FY) 2010, Pacific Northwest National Laboratory (PNNL) Environmental Protection and Regulatory Programs Division (before March 1, 2011 known as the Environmental Management Services Department) staff performed a number of activities as part of PNNL’s National Environmental Policy Act (NEPA) compliance program. These activities helped to verify U.S. Department of Energy (DOE) Pacific Northwest Site Office (PNSO) and Richland Operations Office (RL) compliance with NEPA requirements and streamline the NEPA process for federal activities conducted at PNNL. Self-assessments were performed to address NEPA compliance and cultural and biological resource protection. The NEPA self-assessments focused on implementation within the PNNL Energy and Environment Directorate and routine maintenance activities conducted during the previous calendar year. The cultural and biological resource self-assessments were conducted in accordance with the PNSO Cultural and Biological Resources Management Plan, which specifies annual monitoring of important resources to assess and document the status of the resources and the associated protective mechanisms in place to protect sensitive resources.

  10. Regulation of caulimovirus gene expression and the involvement of cis-acting elements on both viral transcripts.

    PubMed

    Scholthof, H B; Wu, F C; Gowda, S; Shepherd, R J

    1992-09-01

    In a further analysis of gene regulation of figwort mosaic virus (FMV), a caulimovirus, we studied transient gene expression with modified viral genomes in Nicotiana edwardsonii cell suspension protoplasts. The results demonstrated that the presence of the promoter for the full-length RNA interferes with expression from the separate downstream promoter for gene VI. In addition, expression of gene VI was inhibited by cis-acting sequences within gene VI itself. Both inhibitory effects could be partially relieved by coelectroporation with a plasmid that produces gene VI protein, demonstrating that expression of gene VI is transactivated by its own product. Subsequent expression studies with partially redundant FMV plasmids containing a reporter gene in frame with gene IV showed that efficient transactivation of CAT expression relies on a cis-acting element inside the downstream gene VI. Insertions of a transcriptional terminator upstream of the cis-acting element for premature termination of transcription showed that the cis-acting region is not a DNA element but is active only as a feature of the RNA transcript. We conclude that the cis-acting element, together with the transacting gene VI product, enhances expression of all major genes, including gene VI, from the polycistronic mRNA and the separate mRNA for gene VI.

  11. 77 FR 50561 - Livestock Mandatory Reporting Program; Establishment of the Reporting Regulation for Wholesale Pork

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ..., 2000, AMS published the final rule to implement the LMR program as required by the 1999 Act (65 FR... April 2, 2001 (66 FR 8151). The statutory authority for the program lapsed on September 30, 2005. At... changes. On May 16, 2008, USDA published the final rule to re-establish and revise the LMR program (73...

  12. A programmed –1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element

    PubMed Central

    Plant, Ewan P.; Wang, Pinger; Jacobs, Jonathan L.; Dinman, Jonathan D.

    2004-01-01

    Nonsense-mediated mRNA decay (NMD) directs rapid degradation of premature termination codon (PTC)-containing mRNAs, e.g. those containing frameshift mutations. Many viral mRNAs encode polycistronic messages where programmed –1 ribosomal frameshift (–1 PRF) signals direct ribosomes to synthesize polyproteins. A previous study, which identified consensus –1 PRF signals in the yeast genome, found that, in contrast to viruses, the majority of predicted –1 PRF events would direct translating ribosomes to PTCs. Here we tested the hypothesis that a –1 PRF signal can function as a cis-acting mRNA destabilizing element by inserting an L-A viral –1 PRF signal into a PGK1 reporter construct in the ‘genomic’ orientation. The results show that even low levels of –1 PRF are sufficient to target the reporter mRNA for degradation via the NMD pathway, with half-lives similar to messages containing in-frame PTCs. The demonstration of an inverse correlation between frameshift efficiency and mRNA half-lives suggests that modulation of –1 PRF frequencies can be used to post-transcriptionally regulate gene expression. Analysis of the mRNA decay profiles of the frameshift-signal- containing reporter mRNAs also supports the notion that NMD remains active on mRNAs beyond the ‘pioneer round’ of translation in yeast. PMID:14762205

  13. 75 FR 51420 - Removing Regulations Implementing the Fish and Wildlife Conservation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... implementing regulations (50 CFR 83) in the May 6, 2010, Federal Register (75 FR 24862) and invited public... with Native American Tribal Governments'' (59 FR 22951), E.O. 13175, and 512 DM 2. We have determined... Fish and Wildlife Service 50 CFR Part 83 RIN 1018-AX00 Removing Regulations Implementing the Fish...

  14. 76 FR 78483 - S.A.F.E. Mortgage Licensing Act (Regulations G & H)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... Insurance Corporation, and the Department of Housing and Urban Development for the Secure and Fair... regulated by the Farm Credit Administration. This interim final rule does not impose any new substantive... by a Federal banking agency, or employees of institutions regulated by the Farm Credit...

  15. 76 FR 57940 - Revision of Department of Justice Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ..., the regulations will be updated to reflect developments in the case law and to include current cost... NRPM published on March 21, 2011 (76 FR 15236), closed on April 20, 2011. This document reopens the... revising its existing regulations under the FOIA. (See 76 FR 15236.) The rule proposed to amend...

  16. 75 FR 29447 - Public Health Service Act, Rural Physician Training Grant Program, Definition of “Underserved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... Program, Definition of ``Underserved Rural Community'' AGENCY: Health Resources and Services... statutory directive to issue a regulation defining ``underserved rural community'' for purposes of the Rural... ``Underserved Rural Community'' A. Definition of Rural B. Definition of Underserved IV. Collection...

  17. Twenty Years of the Dietary Supplement Health and Education Act--How Should Dietary Supplements Be Regulated?

    PubMed

    Wallace, Taylor C

    2015-08-01

    The Dietary Supplement Health and Education Act (DSHEA) of 1994 defines the FDA's statutory authority to regulate dietary supplement products in the United States. The dietary supplement industry has rapidly expanded since 1994, presenting an obvious need for "DSHEA 2.0." Current regulations surrounding dietary supplements have been increasingly and reasonably scrutinized, given their widespread use by over one-half of the US population as well as highly publicized safety concerns over the past 20 y. As the market continues to expand and evolve, so too must the laws that protect consumers from potential harm and misleading communication. This article is meant to begin a scientific dialogue on how regulations may be improved to provide both ease of access and safer products to the consumer by focusing on 4 topics: premarket approval, label claims, current Good Manufacturing Practices, and adverse event reporting. PMID:26063064

  18. Twenty Years of the Dietary Supplement Health and Education Act--How Should Dietary Supplements Be Regulated?

    PubMed

    Wallace, Taylor C

    2015-08-01

    The Dietary Supplement Health and Education Act (DSHEA) of 1994 defines the FDA's statutory authority to regulate dietary supplement products in the United States. The dietary supplement industry has rapidly expanded since 1994, presenting an obvious need for "DSHEA 2.0." Current regulations surrounding dietary supplements have been increasingly and reasonably scrutinized, given their widespread use by over one-half of the US population as well as highly publicized safety concerns over the past 20 y. As the market continues to expand and evolve, so too must the laws that protect consumers from potential harm and misleading communication. This article is meant to begin a scientific dialogue on how regulations may be improved to provide both ease of access and safer products to the consumer by focusing on 4 topics: premarket approval, label claims, current Good Manufacturing Practices, and adverse event reporting.

  19. The Impact of Public Affairs Programming Regulation: A Study of the FCC's Effectiveness.

    ERIC Educational Resources Information Center

    Chamberlin, Bill F.

    1979-01-01

    Explores the effectiveness of the Federal Communications Commission (FCC) public affairs program regulation through analysis of annual reports for 75 television stations, examining amount of time for public issues programing, amount of local affairs programing, total prime time programing, and whether FCC standards are met. (CWM)

  20. Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in Shewanella oneidensis MR-1

    SciTech Connect

    Cruz-Garza, Claribel; Murray, Alison E.; Rodrigues, Jorge L.M.; Gralnick, Jeffrey A.; McCue, Lee Ann; Romine, Margaret F.; Loffler, F. E.; Tiedje, James M.

    2011-03-30

    EtrA in Shewanella oneidensis MR-1, a model organism for study of adaptation to varied redox niches, shares 73.6% and 50.8% amino acid sequence identity with the oxygen-sensing regulators Fnr in E. coli and Anr in Pseudomonas aeruginosa, respectively; however, its regulatory role of anaerobic metabolism in Shewanella spp. is not well understood. The expression of the nap genes, nrfA, cymA and hcp was significantly reduced in etrA deletion mutant EtrA7-1; however, limited anaerobic growth and nitrate reduction occurred, suggesting that multiple regulators control nitrate reduction in this strain. Dimethyl sulfoxide (DMSO) and fumarate reductase gene expression was down regulated at least 2-fold and the EtrA7-1 mutant grew poorly with fumarate and dimethyl sulfoxide (DMSO), suggesting both respiratory pathways are under EtrA control. Transcript analysis further suggested a role of EtrA in prophage activation and down regulation of genes implicated in aerobic metabolism. In contrast to previous studies that attributed a minor regulatory role to EtrA in Shewanella spp., this study demonstrates that EtrA acts as a global transcriptional regulator and confers physiological advantages to strain MR-1 under certain growth conditions. In conjunction with other regulators, EtrA fine-tunes the expression of genes involved in anaerobic metabolism in S. oneidensis strain MR-1.

  1. Compliance with the Clean Air Act Title VI Stratospheric Ozone Protection Program requirements at U.S. DOE Oak Ridge Reservation Facilities

    SciTech Connect

    Humphreys, M.P.; Atkins, E.M.

    1999-07-01

    The Title VI Stratospheric Ozone Protection Program of the Clean Air Act (CAA) requires promulgation of regulations to reduce and prevent damage to the earth's protective ozone layer. Regulations pursuant to Title VI of the CAA are promulgated in the Code of Federal Regulations (CFR) at Title 40 CFR, Part 822. The regulations include ambitious production phaseout schedules for ozone depleting substances (ODS) including chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), halons, carbon tetrachloride, and methyl chloroform under 40 CFR 82, Subpart A. The regulations also include requirements for recycling and emissions reduction during the servicing of refrigeration equipment and technician certification requirements under Subpart F; provisions for servicing of motor vehicle air conditioners under Subpart B; a ban on nonessential products containing Class 1 ODS under Subpart C; restrictions on Federal procurement of ODS under Subpart D; labeling of products using ODS under Subpart E; and the Significant New Alternatives Policy Program under Subpart G. This paper will provide details of initiatives undertaken at US Department of Energy (DOE) Oak Ridge Reservation (ORR) Facilities for implementation of requirements under the Title VI Stratospheric Ozone Protection Program. The Stratospheric Ozone Protection Plans include internal DOE requirements for: (1) maintenance of ODS inventories; (2) ODS procurement practices; (3) servicing of refrigeration and air conditioning equipment; (4) required equipment modifications or replacement; (5) technician certification training; (6) labeling of products containing ODS; (7) substitution of chlorinated solvents; and (8) replacement of halon fire protection systems. The plans also require establishment of administrative control systems which assure that compliance is achieved and maintained as the regulations continue to develop and become effective.

  2. 20 CFR 668.870 - What is “program income” and how is it regulated in the INA program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... program? (a) Program income is defined and regulated by WIA section 195(7), 20 CFR 667.200(a)(5) and the applicable rules in 29 CFR parts 95 and 97. (b) For grants made under this part, program income does not... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What is âprogram incomeâ and how is...

  3. 78 FR 36693 - Rules and Regulations Under the Fur Products Labeling Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... guaranties annually. \\10\\ 78 FR 29263 (May 20, 2013). In light of the proposed amendments to the Textile... Act, 77 FR 57043 (Sept. 17, 2012). \\8\\ National Retail Federation Comment 00025 at 1-5, available at... Activities; Submission for OMB Review; Comment Request, 7 FR 10744 (Feb. 23, 2012). D. Projected...

  4. 20 CFR 626.4 - Table of contents for the Job Training Partnership Act regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....805Security and law enforcement. 638.806Property management and procurement. 638.807Imprest and petty cash... the Job Training Partnership Act, 20 CFR parts 626-638 and 1005, 1 is as follows: 1 Part 1005 was...-risk” recipients and subrecipients. 627.424Prohibition of subawards to debarred and suspended...

  5. 77 FR 43782 - Acquisition Regulations; Buy Indian Act; Procedures for Contracting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... Planning and Review (Executive Order 12866) B. Regulatory Flexibility Act C. Small Business Regulatory... to set aside procurement contracts for Indian-owned and controlled businesses. This rule supplements... ownership of business enterprises from a mandatory 100 percent to minimum 51 percent. In addition,...

  6. 76 FR 63817 - Disclosure of Information; Privacy Act Regulations; Notice and Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ... supervisory agency, for purposes of Sec. 309.6, to which exempt records could be disclosed.\\1\\ \\1\\ 76 FR 35963.... D. Plain Language Section 722 of the Gramm-Leach-Bliley Act (Pub. L. 106-102, 113 Stat. 1338, 1471), requires the Federal banking agencies to use plain language in all proposed and final rules published...

  7. 77 FR 23196 - Native American Graves Protection and Repatriation Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... Office of the Secretary 43 CFR Part 10 RIN 1024-AD99 Native American Graves Protection and Repatriation... Secretary of the Interior (Secretary) is responsible for implementation of the Native American Graves... implementing the Native American ] Graves Protection and Repatriation Act for purposes of factual accuracy...

  8. Trans-acting factors regulate the expression of CD44 splice variants.

    PubMed Central

    Konig, H; Moll, J; Ponta, H; Herrlich, P

    1996-01-01

    Variant isoforms of the cell surface glycoprotein CD44 (CD44v) are expressed during development, in selected adult tissues and in certain metastatic tumor cells. CD44v differ from the standard isoform (CD44s) by up to ten additional exon sequences included by alternative splicing. By cell fusion experiments, we have obtained evidence for the existence of cell-type specific trans-acting factors recruiting CD44 variant exon sequences. Stable cell hybrids of CD44s and CD44v expressing cells indicated a dominant mechanism for variant-exon inclusion. In transient interspecies heterokaryons of human keratinocytes and rat fibroblasts, the ability of the keratinocytes to include all variant exon sequences in CD44 was conferred completely on the rat fibroblast nucleus. Fusions of cells with complex CD44 splice patterns do not permit interpretation of splice control by the relative abundance of a single trans-acting factor, but rather by (a) positively acting factor(s) recruiting variant exon sequences in the 3' to 5' direction and additional factors selecting individual exons. Since the pancreatic carcinoma cell line BSp73ASML (in contrast to the cervix carcinoma cell lines SiHa and ME180) could not transfer its specific splice pattern in cell fusions, we conclude that in some tumors, splicing is also controlled by mutation of cis-acting recognition sites. Images PMID:8670907

  9. 77 FR 74546 - Posting of Pamphlet Provided for in the International Marriage Broker Regulation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... Act, Title D of Public Law 109-162, provided that the Secretary of Homeland Security, in consultation... such pamphlet be posted on the Web sites of the Department of State and all consular posts processing applications for K (fianc (e) or spouse of U.S. citizen) visas. This notice announces that this pamphlet...

  10. 77 FR 29982 - Federal Acquisition Regulation; Submission for OMB Review; Davis Bacon Act-Price Adjustment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ...: A. Purpose Government contracting officers may include FAR clause 52.222-32, Davis-Bacon Act--Price... may reasonably require. The information is used by ] Government contracting officers to establish the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF...

  11. 75 FR 63425 - Regulations Implementing the Longshore and Harbor Workers' Compensation Act: Recreational Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... and Harbor Workers' Compensation Act: Recreational Vessels, published on August 17, 2010 (75 FR 50718... comments. 75 FR 50718 (Aug. 17, 2010). As explained in the supplementary information section below, the..., 2009 (see Secretary's Order 10-2009, 74 FR 58834 (Nov. 13, 2009)), that title was no longer...

  12. The Strong Expression and Conserved Regulation of ACT2 in Arabidopsis and Physcomitrella Patens

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Actin genes encode structurally and functionally conserved proteins essential in a variety of cellular functions across eukaryotic species. In this report, we demonstrated that regulatory activity of ACT2 5’ regulatory region was significantly higher than that of the CaMV 35S promoter in Arabidopsis...

  13. Savannah River Site, Liquid Waste Program, Savannah River Remediation American Recovery and Reinvestment Act Benefits and Lessons Learned - 12559

    SciTech Connect

    Schmitz, Mark A.; Crouse, Thomas N.

    2012-07-01

    Utilizing funding provided by the American Recovery and Reinvestment Act (ARRA), the Liquid Waste Program at Savannah River site successfully executed forty-one design, procurement, construction, and operating activities in the period from September 2009 through December 2011. Project Management of the program included noteworthy practices involving safety, integrated project teams, communication, and cost, schedule and risk management. Significant upgrades to plant capacity, progress toward waste tank closure and procurement of needed infrastructure were accomplished. Over 1.5 million hours were worked without a single lost work day case. Lessons Learned were continually identified and applied to enhance the program. Investment of Recovery Act monies into the Liquid Waste Program has ensured continued success in the disposition of radioactive wastes and the closure of high level waste tanks at SRS. The funding of a portion of the Liquid Waste Program at SRS by ARRA was a major success. Significant upgrades to plant capacity, progress toward waste tank closure and procurement of needed infrastructure was accomplished. Integrated Project Teams ensured quality products and services were provided to the Operations customers. Over 1.5 million hours were worked without a single lost work day case. Lessons Learned were continually reviewed and reapplied to enhance the program. Investment of Recovery Act monies into the Liquid Waste Program has ensured continued success in the disposition of radioactive wastes and the closure of high level waste tanks at SRS. (authors)

  14. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... regulations at 29 CFR parts 1, 3, and 5, including the requirements contained in the Davis-Bacon contract provisions set forth in 29 CFR 5.5. (b) YouthBuild participants are subject to Davis-Bacon Act labor standards when they perform Davis-Bacon-covered laborer or mechanic work, defined at 29 CFR 5.2, on...

  15. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... regulations at 29 CFR parts 1, 3, and 5, including the requirements contained in the Davis-Bacon contract provisions set forth in 29 CFR 5.5. (b) YouthBuild participants are subject to Davis-Bacon Act labor standards when they perform Davis-Bacon-covered laborer or mechanic work, defined at 29 CFR 5.2, on...

  16. 20 CFR 672.545 - Are YouthBuild programs subject to the Davis-Bacon Act labor standards?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... regulations at 29 CFR parts 1, 3, and 5, including the requirements contained in the Davis-Bacon contract provisions set forth in 29 CFR 5.5. (b) YouthBuild participants are subject to Davis-Bacon Act labor standards when they perform Davis-Bacon-covered laborer or mechanic work, defined at 29 CFR 5.2, on...

  17. 40 CFR 49.7 - Request by an Indian tribe for eligibility determination and Clean Air Act program approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND... Indian tribe's authority to regulate air quality. For applications covering areas within the exterior... Self-Determination and Education Assistance Act (25 U.S.C. 450, et seq.), the Indian...

  18. 45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Program Design and Operations §...

  19. 75 FR 66699 - Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ... published in the Federal Register (75 FR 46859-46861, Docket No. APHIS-2009-0018) a proposal to establish... Implementation Plan; Definitions for Exempt and Regulated Articles AGENCY: Animal and Plant Health...

  20. 75 FR 3665 - Regulations under the Comprehensive Smokeless Tobacco Health Education Act; Termination of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... cars, banners, flags, and other event-related objects. On November 4, 1993 (58 FR 58810), the FTC... Tobacco to Protect Children and Adolescents, 61 FR 44615-618 (Aug. 28, 1996). Those regulations...