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Sample records for act tsca chemical

  1. 8(E) TRIAGE CHEMICAL STUDIES DATABASE (TSCA)

    EPA Science Inventory

    The Toxic Substances Control Act (TSCA) gives the Environmental Protection Agency (EPA) the authority and responsibility to identify and control chemical hazards to human health or the environment. TSCA gives the EPA authority to gather certain kinds of basic information on chemi...

  2. Toxic Substances Control Act (TSCA) chemical substances inventory: PMN number to EPA accession number link (for microcomputers). Data file

    SciTech Connect

    Not Available

    1994-05-01

    The PMN Number to EPA Accession Number Link Diskette provides a cross-reference of these numbers for commenced PMNs on the confidential portion of the Toxic Substances Control Act (TSCA) Master Inventory File. Neither this cross-reference nor the additional information included is TSCA Confidential Business Information. Provided on the diskette for each confidential commenced PMN are the PMN Case Number, EPA Accession Number, Generic Name, and EPA special flags. For more detailed information on the confidential portion of the TSCA Inventory, including generic names, users can consult the introductory material of the printed TSCA Inventory: 1985 Edition and its 1990 Supplement. New versions of this file may be issued in the future.

  3. 78 FR 64936 - Dichloromethane and N-Methylpyrrolidone TSCA Chemical Risk Assessment; Notice of Rescheduled...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... AGENCY Dichloromethane and N-Methylpyrrolidone TSCA Chemical Risk Assessment; Notice of Rescheduled... regarding EPA's draft Toxic Substances Control Act (TSCA) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for Dichloromethane and N-Methylpyrrolidone.'' The first meeting was held as...

  4. 78 FR 67141 - Antimony Trioxide (ATO) TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... AGENCY Antimony Trioxide (ATO) TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity... Substances Control Act (TSCA) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for ATO... CONTACT: For technical information contact: Stan Barone, Jr., Risk Assessment Division (7403M), Office...

  5. 78 FR 59679 - Antimony Trioxide TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... AGENCY Antimony Trioxide TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity To... review of EPA's draft Toxic Substances Control Act (TSCA) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for Antimony Trioxide.'' EPA will hold three peer review meetings by web...

  6. Testing decisions of the TSCA Interagency Testing Committee for chemicals on the Canadian Environmental Protection Act Domestic Substances List and Priority Substances List: Di-tert-butylphenol, ethyl benzene, brominated flame retardants, phthalate esters, chloroparaffins, chlorinated benzenes, and anilines

    SciTech Connect

    Walker, J.D.

    1996-12-31

    In 1976, under section 4(e) of the Toxic Substances Control Act (TSCA), the US Congress created the TSCA Interagency Testing Committee (ITC) to decide which chemicals should be recommended to the Administrator of the US Environmental Protection Agency for testing. In 1988, under the Canadian Environmental Protection Act (CEPA), the Government of Canada created the Domestic Substances List and Priority Substances List. This paper briefly describes the ITC, the different ITC testing decisions and a few of the ITC`s 11,150 testing decisions for the 21,413 chemicals on the CEPA Domestic Substances List and some of the 24 testing decisions for the 44 chemicals and chemical groups on the CEPA.

  7. 78 FR 52525 - Dichloromethane and N-Methylpyrrolidone TSCA Chemical Risk Assessment; Notice of Public Meetings...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... notice in the Federal Register (78 FR 1856) (FRL-9375-1) on the availability of five draft TSCA chemical... AGENCY Dichloromethane and N-Methylpyrrolidone TSCA Chemical Risk Assessment; Notice of Public Meetings... assessment, ``TSCA Workplan Chemical Risk Assessment for Dichloromethane and N-Methylpyrrolidone.'' EPA...

  8. Structure activity relationships to assess new chemicals under TSCA

    SciTech Connect

    Auletta, A.E.

    1990-12-31

    Under Section 5 of the Toxic Substances Control Act (TSCA), manufacturers must notify the US Environmental Protection Agency (EPA) 90 days before manufacturing, processing, or importing a new chemical substance. This is referred to as a premanufacture notice (PMN). The PMN must contain certain information including chemical identity, production volume, proposed uses, estimates of exposure and release, and any health or environmental test data that are available to the submitter. Because there is no explicit statutory authority that requires testing of new chemicals prior to their entry into the market, most PMNs are submitted with little or no data. As a result, EPA has developed special techniques for hazard assessment of PMN chemicals. These include (1) evaluation of available data on the chemical itself, (2) evaluation of data on analogues of the PMN, or evaluation of data on metabolites or analogues of metabolites of the PMN, (3) use of quantitative structure activity relationships (QSARs), and (4) knowledge and judgement of scientific assessors in the interpretation and integration of the information developed in the course of the assessment. This approach to evaluating potential hazards of new chemicals is used to identify those that are most in need of addition review of further testing. It should not be viewed as a replacement for testing. 4 tabs.

  9. 76 FR 54932 - TSCA Inventory Update Reporting Modifications; Chemical Data Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ...; Chemical Data Reporting Correction In rule document 2011-19922, appearing on pages 50816-50879 in the issue...)(ii) of the definition importer. ] PART 710--COMPILATION OF THE TSCA CHEMICAL SUBSTANCE INVENTORY 0 3.... * * * * * (b) This part applies to the activities associated with the compilation of the TSCA...

  10. The TSCA interagency testing committee`s approaches to screening and scoring chemicals and chemical groups: 1977-1983

    SciTech Connect

    Walker, J.D.

    1990-12-31

    This paper describes the TSCA interagency testing committee`s (ITC) approaches to screening and scoring chemicals and chemical groups between 1977 and 1983. During this time the ITC conducted five scoring exercises to select chemicals and chemical groups for detailed review and to determine which of these chemicals and chemical groups should be added to the TSCA Section 4(e) Priority Testing List. 29 refs., 1 fig., 2 tabs.

  11. Design of a computerized chemical information file in response to the initial inventory requirements of TSCA.

    PubMed

    Vogt, H C; Kerfoot, E J; Ford, G J

    1980-09-01

    A computerized file of chemical information, "CHEMFO", was developed at BASF Wyandotte Corporation to help comply with the initial reporting requirements of the Toxic Substances Control Act. This organization and approach allowed collecting the required information on all the manufactured and imported chemicals, editing and entry of the data, structuring of the computer file and interactive capabilities, and selecting the final program and subsequent printout. Besides using this system to meet the TSCA initial inventory reporting requirements, the file also has the capacity to be updated and revised as needed, which further expands its potential benefits. Some of the other information that can be derived from this system are: identification of chemical substances, quantities, and each site; tie-in to the medical/occupational health data bank; foundation for recording the industrial hygiene monitoring data; supplement for toxicology and environmental data base; and index for generating compilation of site specific material on health and environmental information. PMID:7457385

  12. 76 FR 50815 - TSCA Inventory Update Reporting Modifications; Chemical Data Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... Update Reporting Modifications; Chemical Data Reporting; Final Rule #0;#0;Federal Register / Vol. 76 , No... Parts 704, 710, and 711 RIN 2070-AJ43 TSCA Inventory Update Reporting Modifications; Chemical Data... definitional modifications and additions. 3. EPA is amending 40 CFR 710.53, which appears in the new 40...

  13. 78 FR 34377 - Trichloroethylene TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ... Risk Assessment for Trichloroethylene: Degreaser and Arts/Crafts Uses.'' EPA will hold three peer..., including one entitled, ``TSCA Workplan Chemical Risk Assessment for Trichloroethylene: Degreaser and Arts/Crafts Uses.'' Trichloroethylene (TCE) (CASRN 79-01-6) is one of 83 chemicals identified for review...

  14. 78 FR 28586 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ...The Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. In addition under TSCA, EPA is required to publish in the Federal......

  15. 77 FR 74473 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ...The Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. In addition under TSCA, EPA is required to publish in the Federal......

  16. 78 FR 35904 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ...The Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. In addition under TSCA, EPA is required to publish in the Federal......

  17. 77 FR 56639 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ...The Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. In addition under TSCA, EPA is required to publish in the Federal......

  18. 77 FR 61600 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ...The Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. In addition under TSCA, EPA is required to publish in the Federal......

  19. 76 FR 38169 - Toxic Substances Control Act Chemical Testing; Receipt of Test Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... FR 22402) (FRL-7312-2), and later amended by a final rule titled ``Revocation of TSCA Section 4... 12, 2006 (71 FR 18650) (FRL-7751-7). Section 4(d) of TSCA (15 U.S.C. 2603(d)) requires EPA to publish... AGENCY Toxic Substances Control Act Chemical Testing; Receipt of Test Data AGENCY:...

  20. Impacts & Compliance Implementation Plans & Required Deviations for Toxic Substance Control Act (TSCA) Regulation of Double Shell Tanks (DST)

    SciTech Connect

    MULKEY, C.H.

    2000-08-22

    In May 2000, the U.S. Department of Energy, Office of River Protection (DOE-ORP) and the U.S. Environmental Protection Agency (EPA) held meetings regarding the management of polychlorinated biphenyls (PCBs) in the Hanford tank waste. It was decided that the radioactive waste currently stored in the double-shell tanks (DSTs) contain waste which will become subject to the Toxic Substance Control Act (TSCA) (40 CFR 761). As a result, DOE-ORP directed the River Protection Project tank farm contractor (TFC) to prepare plans for managing the PCB inventory in the DSTs. Two components of the PCB management plans are this assessment of the operational impacts of TSCA regulation and the identifications of deviations from TSCA that are required to accommodate tank farm unique limitations. This plan provides ORP and CH2M HILL Hanford Group, Inc. (CHG) with an outline of TSCA PCB requirements and their applicability to tank farm activities, and recommends a compliance/implementation approach. Where strict compliance is not possible, the need for deviations from TSCA PCB requirements is identified. The purpose of assembling this information is to enhance the understanding of PCB management requirements, identify operational impacts and select impact mitigation strategies. This information should be useful in developing formal agreements with EPA where required.

  1. The TSCA Interagency Testing Committee (ITC) proposed strategy for identifying and coordinating U.S. government data needs for endocrine-disrupting chemicals

    SciTech Connect

    Walker, J.D.

    1995-12-31

    The ITC`s Endocrine-Disrupting Chemicals Subcommittee will implement a proposed strategy for identifying and coordinating the US government ecological and health effects data needs for endocrine-disrupting chemicals, These include chemicals with potential to cause reproductive, developmental, immunological, neurologic or other biological effects by adversely affecting endocrine tissues, hormones or receptors in fish, wildlife or humans. To meet these needs, the Subcommittee will consider three options. First, the information collecting authority of the Toxic Substances Control Act (TSCA) will be considered as a cost-effective mechanism to rapidly (within 60 days) obtain unpublished health and ecological effects studies related to reproductive effects and endocrine-disrupting activity. Second, the chemical testing authority of TSCA will be considered as a method to request that the manufacturers of endocrine-disrupting chemicals conduct tests that are amenable to standardization. Third, consideration will be given to coordinating standardized testing with testing related to research and to using the results of this research to develop standardized methods for assessing the effects of endocrine-disrupting chemicals. The Subcommittee will focus on 16 alkylphenol and alkylphenol ethoxylates with 1989 production or importation volumes greater than 1 million pounds that were identified using the Substructure based Computerized Chemical Selection Expert System (SuCCSES). The ITC`s proposed strategy will be discussed.

  2. 77 FR 45600 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  3. 76 FR 43327 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  4. 76 FR 57734 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  5. 77 FR 48514 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  6. 76 FR 69723 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  7. 77 FR 10512 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  8. 76 FR 76963 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  9. 76 FR 58498 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  10. 76 FR 36109 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under TSCA sections 5(d)(2) and 5(d)(3), EPA is required......

  11. Regulating the introduction of new chemicals under section 5 of TSCA: improving the efficiency of the process and reducing potential injury in the workplace through the use of operational MSDS and exposure limits.

    PubMed

    Rosenthal, I; Jayjock, M A; Keener, R L; Plamondon, J E

    1991-10-01

    The Toxic Substances Control Act (TSCA) authorizes the EPA to take appropriate actions to ensure that new and existing chemicals do not pose "unreasonable risk" to health or the environment. Section 2(b)(3) of the Act directs the Agency to accomplish this objective in a manner that does "not impede unduly or create unnecessary economic barriers to technological innovation." In recent years, critics have felt that the EPA has failed to achieve these primary goals of TSCA. This paper considers some of the reasons for this criticism and advocates an alternate approach of exposure limits and operationally sufficient controls to assist in achieving these goals. An illustration of how this alternate approach might work under practical conditions is presented, using as an example a new chemical substance from the class of acrylate monomers. These concepts and risk assessments provide data for a better design of future studies according to good laboratory practice and quality assurance. PMID:1669965

  12. 40 CFR 799.9346 - TSCA 90-day inhalation toxicity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA 90-day inhalation toxicity. 799.9346 Section 799.9346 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines...

  13. 40 CFR 799.9510 - TSCA bacterial reverse mutation test.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA bacterial reverse mutation test. 799.9510 Section 799.9510 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines...

  14. 40 CFR 799.9510 - TSCA bacterial reverse mutation test.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false TSCA bacterial reverse mutation test. 799.9510 Section 799.9510 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines...

  15. 75 FR 8266 - Final Clarification for Chemical Identification Describing Activated Phosphors for TSCA Inventory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... in the Federal Register issue of January 16, 2008 (73 FR 2854) (FRL-8131-8) and a reopening of comments on the proposed clarification was announced in the Federal Register issue of May 2, 2008 (73 FR... Federal Register issue of December 23, 1977 (42 FR 64572) under TSCA section 8(a), 15 U.S.C. 2607(a),...

  16. Mode of action and the assessment of chemical hazards in the presence of limited data: use of structure-activity relationships (SAR) under TSCA, Section 5.

    PubMed Central

    Auer, C M; Nabholz, J V; Baetcke, K P

    1990-01-01

    Section 5 of the Toxic Substances Control Act (TSCA) requires that manufacturers and importers of new chemicals must submit a Premanufacture Notification (PMN) to the U.S. Environmental Protection Agency 90 days before they intend to commence manufacture or import. Certain information such as chemical identity, uses, etc., must be included in the notification. The submission of test data on the new substance, however, is not required, although any available health and environmental information must be provided. Nonetheless, over half of all PMNs submitted to the agency do not contain any test data; because PMN chemicals are new, no test data is generally available in the scientific literature. Given this situation, EPA has had to develop techniques for hazard assessment that can be used in the presence of limited test data. EPA's approach has been termed "structure-activity relationships" (SAR) and involves three major components: the first is critical evaluation and interpretation of available toxicity data on the chemical; the second component involves evaluation of test data available on analogous substances and/or potential metabolites; and the third component involves the use of mathematical expressions for biological activity known as "quantitative structure-activity relationships" (QSARs). At present, the use of QSARs is limited to estimating physical chemical properties, environmental toxicity, and bioconcentration factors. An important overarching element in EPA's approach is the experience and judgment of scientific assessors in interpreting and integrating the available data and information. Examples are provided that illustrate EPA's approach to hazard assessment for PMN chemicals. PMID:2269224

  17. 75 FR 57770 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  18. 75 FR 60444 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  19. 75 FR 39520 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  20. 75 FR 11414 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  1. 75 FR 11403 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  2. 75 FR 32754 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ...Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of......

  3. 40 CFR 799.9305 - TSCA Repeated dose 28-day oral toxicity study in rodents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA Repeated dose 28-day oral toxicity study in rodents. 799.9305 Section 799.9305 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING REQUIREMENTS Health...

  4. 40 CFR 799.9530 - TSCA in vitro mammalian cell gene mutation test.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false TSCA in vitro mammalian cell gene mutation test. 799.9530 Section 799.9530 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING REQUIREMENTS Health Effects...

  5. 77 FR 48858 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ...EPA is promulgating significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for 25 chemical substances which were the subject of premanufacture notices (PMNs). Fourteen of these chemical substances are subject to TSCA section 5(e) consent orders issued by EPA. This action requires persons who intend to manufacture, import, or process any of these 25 chemical substances......

  6. 77 FR 58665 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ...EPA is promulgating significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for 107 chemical substances which were the subject of premanufacture notices (PMNs). Eight of these chemical substances are subject to TSCA consent orders issued by EPA. This action requires persons who intend to manufacture, import, or process any of these 107 chemical substances for an......

  7. 40 CFR 799.9365 - TSCA combined repeated dose toxicity study with the reproduction/developmental toxicity screening...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA combined repeated dose toxicity study with the reproduction/developmental toxicity screening test. 799.9365 Section 799.9365 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL...

  8. 77 FR 36170 - TSCA Inventory Update Reporting Modifications; Chemical Data Reporting; 2012 Submission Period...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Reporting Modifications; Chemical Data Reporting'' (76 FR 50816, August 16, 2011) (FRL-8872-9), EPA... ``Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use'' (66 FR... and Review'' (58 FR 51735, October 4, 1993) and Executive Order 13563 entitled ``Improving...

  9. Reauthorization of Toxic Substances Control Act for fiscal year 1984. Hearing before the Subcommittee on Commerce, Transportation, and Tourism of the Committee on Energy and Commerce, House of Representatives, Ninety-Eighth Congress, First Session, April 21, 1983

    SciTech Connect

    Not Available

    1983-01-01

    A hearing to reauthorize the Toxic Substances Control Act (TSCA) reviewed evidence that few new chemicals introduced into the consumer market are tested for toxicity and that no testing rules have been issued in the seven years of TSCA's existence in contrast to the testing record of some European countries. The 13 witnesses represented the Chamber of Commerce, conservation and environmental groups and agencies, and manufacturers of potentially toxic materials. The latter cited the economic burden on small businesses and the constraints on innovation that TSCA has had. Others stressed potential health hazards from untested materials and the poor record of TSCA implementation. (DCK)

  10. 77 FR 30855 - Sixty-Ninth Report of the TSCA Interagency Testing Committee to the Administrator of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ...The Toxic Substances Control Act (TSCA) Interagency Testing Committee (ITC) transmitted its 69th Report to the EPA Administrator on April 5, 2012. In the 69th ITC Report, which is included with this notice, the ITC is adding a category of cadmium compounds including any chemical that contains cadmium as part of that chemical's structure, 6 non-phthalate plasticizers, 25 phosphate ester flame......

  11. Toxic Substances Control Act (TSCA) Polychlorinated Biphenyl (PCB)/Radioactive Waste Annual Inventory for Calendar Year 2013

    SciTech Connect

    no author on report

    2014-06-01

    The Toxic Substances Control Act, 40 CFR 761.65(a)(1) provides an exemption from the one year storage time limit for PCB/radioactive waste. PCB/radioactive waste may exceed the one year time limit provided that the provisions at 40 CFR 761.65(a)(2)(ii) and 40 CFR 761.65(a)(2)(iii) are followed. These two subsections require, (ii) "A written record documenting all continuing attempts to secure disposal is maintained until the waste is disposed of" and (iii) "The written record required by subsection (ii) of this section is available for inspection or submission if requested by EPA." EPA Region 10 has requested the Department of Energy (DOE) to submit an inventory of radioactive-contaminated PCB waste in storage at the Idaho National Laboratory (INL) for the previous calendar year. The annual inventory is separated into two parts, INL without Advanced Mixed Waste Treatment Project (AMWTP) (this includes Battelle Energy Alliance, LLC, CH2M-WG Idaho, LLC, and the Naval Reactors Facility), and AMWTP.

  12. Toxic Substances Control Act (TSCA) Polychlorinated Biphenyl (PCB)/Radioactive Waste Annual Inventory for Calendar Year 2014

    SciTech Connect

    Layton, Deborah L.

    2015-06-01

    The Toxic Substances Control Act, 40 CFR 761.65(a)(1) provides an exemption from the one year storage time limit for PCB/radioactive waste. PCB/radioactive waste may exceed the one year time limit provided that the provisions at 40 CFR 761.65(a)(2)(ii) and 40 CFR 761.65(a)(2)(iii) are followed. These two subsections require, (ii) "A written record documenting all continuing attempts to secure disposal is maintained until the waste is disposed of" and (iii) "The written record required by subsection (ii) of this section is available for inspection or submission if requested by EPA." EPA Region 10 has requested the Department of Energy (DOE) to submit an inventory of radioactive-contaminated PCB waste in storage at the Idaho National Laboratory (INL) for the previous calendar year. The annual inventory is separated into two parts, INL without Advanced Mixed Waste Treatment Project (AMWTP) (this includes Battelle Energy Alliance, LLC, CH2M-WG Idaho, LLC, and the Naval Reactors Facility), and AMWTP.

  13. 78 FR 27860 - Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical Substance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-13

    ... Certain High Production Volume Chemicals; Final Rule. Federal Register (71 FR 13708, March 16, 2006) (FRL... Requirements Certain High Production Volume Chemical Substances; Direct Final Rule. Federal Register (77 FR... Substance; Final Rule. Federal Register (77 FR 28281, May 14, 2012) (FRL-9350- 2). Document ID number...

  14. CHEMICAL CATEGORIES IN EPA'S NEW CHEMICALS PROGRAM

    EPA Science Inventory

    Under section 5 of the Toxic Substances Control Act (TSCA),any person who intends to manufacture or import a new chemical substance, or mixture containing such a substance, in the United States for commercial purposes must submit a premanufacture notice (PMN) to the Environmental...

  15. 78 FR 41768 - Chemical Substances and Mixtures Used in Oil and Gas Exploration or Production; TSCA Section 21...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-11

    ... Significant Human Exposure; Final Statement of Policy. Federal Register (58 FR 28736, May 14, 1993) (FRL-4059... AGENCY 40 CFR Chapter I Chemical Substances and Mixtures Used in Oil and Gas Exploration or Production...(a) to require manufacturers and processors of oil and gas exploration and production (E&P)...

  16. 77 FR 28340 - Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical Substance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... High Production Volume Chemicals; Final Rule. Federal Register (71 FR 13708, March 16, 2006) (FRL-7335... significant regulatory action under Executive Order 12866, entitled ``Regulatory Planning and Review'' (58 FR... Environmental Health Risks and Safety Risks'' (62 FR 19885, April 23, 1997), and Executive Order 13211,...

  17. 76 FR 1067 - Testing of Certain High Production Volume Chemicals; Second Group of Chemicals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ...EPA is promulgating a final rule under section 4(a)(1)(B) of the Toxic Substances Control Act (TSCA) to require manufacturers, importers, and processors of certain high production volume (HPV) chemical substances to conduct testing to obtain screening level data for health and environmental effects and chemical...

  18. 77 FR 21769 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory... manufacture a new chemical that the Agency has received under TSCA section 5 during this time period....

  19. 77 FR 5100 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory... the NOC to manufacture a new chemical that the Agency has received under TSCA section 5 during...

  20. 77 FR 48976 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Chemical Substances Inventory (TSCA Inventory)) to notify EPA and comply with the statutory... manufacture a new chemical that the Agency has received under TSCA section 5 during this time period....

  1. 78 FR 27048 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ...EPA is promulgating significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for 15 chemical substances which were the subject of premanufacture notices (PMNs). This action requires persons who intend to manufacture, import, or process any of these 15 chemical substances for an activity that is designated as a significant new use by this rule to notify EPA at least 90......

  2. 40 CFR 799.9135 - TSCA acute inhalation toxicity with histopathology.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Substances Control Act (TSCA). In the assessment and evaluation of the potential human health effects of..., brain, and gonads shall be weighed wet, as soon as possible after dissection to avoid drying. (iii) The... possible future histopathological examination: All gross lesions; brain-including sections of...

  3. 40 CFR 799.9135 - TSCA acute inhalation toxicity with histopathology.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Substances Control Act (TSCA). In the assessment and evaluation of the potential human health effects of..., brain, and gonads shall be weighed wet, as soon as possible after dissection to avoid drying. (iii) The... possible future histopathological examination: All gross lesions; brain-including sections of...

  4. 40 CFR 799.9135 - TSCA acute inhalation toxicity with histopathology.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Substances Control Act (TSCA). In the assessment and evaluation of the potential human health effects of..., brain, and gonads shall be weighed wet, as soon as possible after dissection to avoid drying. (iii) The... possible future histopathological examination: All gross lesions; brain-including sections of...

  5. 40 CFR 799.9135 - TSCA acute inhalation toxicity with histopathology.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Substances Control Act (TSCA). In the assessment and evaluation of the potential human health effects of..., brain, and gonads shall be weighed wet, as soon as possible after dissection to avoid drying. (iii) The... possible future histopathological examination: All gross lesions; brain-including sections of...

  6. 40 CFR 799.9135 - TSCA acute inhalation toxicity with histopathology.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Substances Control Act (TSCA). In the assessment and evaluation of the potential human health effects of..., brain, and gonads shall be weighed wet, as soon as possible after dissection to avoid drying. (iii) The... possible future histopathological examination: All gross lesions; brain-including sections of...

  7. Glossary of CERCLA, RCRA and TSCA related terms and acronyms. Environmental Guidance

    SciTech Connect

    Not Available

    1993-10-01

    This glossary contains CERCLA, RCRA and TSCA related terms that are most often encountered in the US Department of Energy (DOE) Environmental Restoration and Emergency Preparedness activities. Detailed definitions are included for key terms. The CERCLA definitions included in this glossary are taken from the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), as amended and related federal rulemakings. The RCRA definitions included in this glossary are taken from the Resource Conservation and Recovery Act (RCRA) and related federal rulemakings. The TSCA definitions included in this glossary are taken from the Toxic Substances and Control Act (TSCA) and related federal rulemakings. Definitions related to TSCA are limited to those sections in the statute and regulations concerning PCBs and asbestos.Other sources for definitions include additional federal rulemakings, assorted guidance documents prepared by the US Environmental Protection Agency (EPA), guidance and informational documents prepared by the US Department of Energy (DOE), and DOE Orders. The source of each term is noted beside the term. Terms presented in this document reflect revised and new definitions published before July 1, 1993.

  8. 77 FR 3725 - Proposed Significant New Use Rules on Certain Chemical Substances; Extension of Comment Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... 28, 2011 (76 FR 81441) (FRL-9329-4). In that document, EPA proposed SNURs under section 5(a)(2) of... Substances Control Act (TSCA) for the chemical substances rutile, tin zinc, calcium-doped (CAS No. 389623-01- 2) and rutile, tin zinc, sodium-doped (CAS No. 389623-07-8) which were the subject of...

  9. 76 FR 65385 - Testing of Certain High Production Volume Chemicals; Third Group of Chemicals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ...EPA is promulgating this final rule under section 4(a)(1)(B) of the Toxic Substances Control Act (TSCA) to require manufacturers, importers, and processors to conduct testing to obtain screening level data for health and environmental effects and chemical fate for 15 high production volume (HPV) chemical substances listed in this final rule. This test data is needed in order to help EPA to......

  10. 40 CFR 799.9620 - TSCA neurotoxicity screening battery.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false TSCA neurotoxicity screening battery... REQUIREMENTS Health Effects Test Guidelines § 799.9620 TSCA neurotoxicity screening battery. (a) Scope. This... battery consists of a functional observational battery, motor activity, and neuropathology. The...

  11. 40 CFR 799.9620 - TSCA neurotoxicity screening battery.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false TSCA neurotoxicity screening battery... REQUIREMENTS Health Effects Test Guidelines § 799.9620 TSCA neurotoxicity screening battery. (a) Scope. This... battery consists of a functional observational battery, motor activity, and neuropathology. The...

  12. 40 CFR 799.9620 - TSCA neurotoxicity screening battery.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false TSCA neurotoxicity screening battery... REQUIREMENTS Health Effects Test Guidelines § 799.9620 TSCA neurotoxicity screening battery. (a) Scope. This... battery consists of a functional observational battery, motor activity, and neuropathology. The...

  13. 77 FR 18752 - Benzidine-Based Chemical Substances; Di-n

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ...Under the Toxic Substances Control Act (TSCA), EPA is proposing: To add nine benzidine-based chemical substances to the Significant New Use Rule (SNUR) on benzidine-based chemical substances; a SNUR for di-n-pentyl phthalate (DnPP) (1,2-benzenedicarboxylic acid, 1,2-dipentyl ester) (CAS No. 131-18-0); and a SNUR for alkanes, C12-13, chloro (CAS No. 71011-12-6). In the case of the......

  14. 75 FR 71688 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ...Under sections 5(d)(2) and 5(d)(3) of the Toxic Substances Control Act (TSCA), EPA is required to publish in the Federal Register a notice of receipt of a premanufacture notice (PMN) or an application for a test marketing exemption (TME), and to publish in the Federal Register periodic status reports on the new chemicals under review and the receipt of notices of commencement (NOC) to begin......

  15. U.S. EPA`s use of QSAR for new and existing chemical evaluations: Regulatory aspects

    SciTech Connect

    Zeeman, M.; Clements, R.G.; Nabholz, J.V.; Auer, C.M.

    1994-12-31

    As up front testing is not required, ecotoxicity or fate data are available for only about 5% of the 2,200 new chemicals/year submitted to EPA. The EPA`s Toxic Substances Control Act (TSCA) Inventory of existing chemicals currently lists about 72,000 chemicals. Most of existing chemicals also appear to have little or no ecotoxicity or fate data available. The EPA`s Office of Pollution Prevention and Toxics (OPPT) has developed and relies upon QSARs to estimate the ecotoxicity and fate of most of the new chemicals evaluated for ecological hazard and risk assessment. QSAR methods routinely result in ecotoxicity estimations of acute and sub/chronic toxicity to fish, aquatic invertebrates, and algae, and fate estimations of physical/chemical properties, degradation, and bioconcentration. GSAR methods were also used to screen the TSCA Inventory for the ecotoxicity of specific chemical classes of over 8,000 discrete chemicals. In the latter effort, seven major chemical classes made up almost 95% of these chemicals. From this QSAR analysis, about 10--20% or 15--18% of these chemicals, respectively, are expected to have high acute or high chronic toxicity to aquatic species. Estimates of ecotoxicity for > 8,000 discrete organics enhances prioritization of chemicals on the TSCA Inventory and helps focus EPA/OPPT regulatory efforts upon the potentially most toxic substances.

  16. 78 FR 67142 - HHCB (1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8,-hexamethylcyclopenta[γ]-2-benzopyran) TSCA Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ...) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for HHCB.'' EPA will hold three peer... technical information contact: Stan Barone, Jr., Risk Assessment Division (7403M), Office of Pollution.... Background On January 9, 2013, EPA published a document in the Federal Register (78 FR 1856) (FRL-9375-1)...

  17. 75 FR 49655 - TSCA Inventory Update Reporting Modifications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... Protection Agency 40 CFR Parts 704, 710, and 711 TSCA Inventory Update Reporting Modifications; Proposed Rule... Modifications AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: The Toxic... Business Information (CBI) reporting procedures. These modifications would provide information to...

  18. 40 CFR 799.9355 - TSCA reproduction/developmental toxicity screening test.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards... 40 Protection of Environment 33 2012-07-01 2012-07-01 false TSCA reproduction/developmental... AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines § 799.9355 TSCA...

  19. 40 CFR 799.9355 - TSCA reproduction/developmental toxicity screening test.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards... 40 Protection of Environment 32 2011-07-01 2011-07-01 false TSCA reproduction/developmental... AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines § 799.9355 TSCA...

  20. 40 CFR 799.9355 - TSCA reproduction/developmental toxicity screening test.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA reproduction/developmental... AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines § 799.9355 TSCA...

  1. 40 CFR 799.9355 - TSCA reproduction/developmental toxicity screening test.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards... 40 Protection of Environment 31 2010-07-01 2010-07-01 true TSCA reproduction/developmental... AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines § 799.9355 TSCA...

  2. 40 CFR 799.9355 - TSCA reproduction/developmental toxicity screening test.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards... 40 Protection of Environment 32 2014-07-01 2014-07-01 false TSCA reproduction/developmental... AND MIXTURE TESTING REQUIREMENTS Health Effects Test Guidelines § 799.9355 TSCA...

  3. Regulating chemicals: law, science, and the unbearable burdens of regulation.

    PubMed

    Silbergeld, Ellen K; Mandrioli, Daniele; Cranor, Carl F

    2015-03-18

    The challenges of regulating industrial chemicals remain unresolved in the United States. The Toxic Substances Control Act (TSCA) of 1976 was the first legislation to extend coverage to the regulation of industrial chemicals, both existing and newly registered. However, decisions related to both law and science that were made in passing this law inevitably rendered it ineffectual. Attempts to fix these shortcomings have not been successful. In light of the European Union's passage of innovative principles and requirements for chemical regulation, it is no longer possible to deny the opportunity and need for reform in US law and practice. PMID:25785889

  4. 40 CFR 799.9410 - TSCA chronic toxicity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... morphological (pathological) effects. (c) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part... aminotransferase, alkaline phosphatase, sorbitol dehydrogenase, or gamma glutamyl transpeptidase) should also be... requirements specified under EPA Good Laboratory Practice Standards at 40 CFR part 792, subpart J,...

  5. 40 CFR 799.9410 - TSCA chronic toxicity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... morphological (pathological) effects. (c) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part... aminotransferase, alkaline phosphatase, sorbitol dehydrogenase, or gamma glutamyl transpeptidase) should also be... requirements specified under EPA Good Laboratory Practice Standards at 40 CFR part 792, subpart J,...

  6. 40 CFR 799.9130 - TSCA acute inhalation toxicity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Definitions. The definitions in section 3 of TSCA and the definitions in 40 CFR Part 792—Good Laboratory... 40 CFR part 792, subpart f. (3) Test procedures—(i) Preparation. Healthy young adult animals are... at 40 CFR part 792, subpart J, the following specific information must be reported. The test...

  7. 40 CFR 799.9130 - TSCA acute inhalation toxicity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Definitions. The definitions in section 3 of TSCA and the definitions in 40 CFR Part 792—Good Laboratory... 40 CFR part 792, subpart f. (3) Test procedures—(i) Preparation. Healthy young adult animals are... at 40 CFR part 792, subpart J, the following specific information must be reported. The test...

  8. 40 CFR 799.9410 - TSCA chronic toxicity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... morphological (pathological) effects. (c) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part... requirements specified under EPA Good Laboratory Practice Standards at 40 CFR part 792, subpart J, the... equipment. The study must be conducted in compliance with 40 CFR Part 792—Good Laboratory Practice...

  9. 40 CFR 799.9130 - TSCA acute inhalation toxicity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Definitions. The definitions in section 3 of TSCA and the definitions in 40 CFR Part 792—Good Laboratory... 40 CFR part 792, subpart f. (3) Test procedures—(i) Preparation. Healthy young adult animals are... at 40 CFR part 792, subpart J, the following specific information must be reported. The test...

  10. 40 CFR 799.9130 - TSCA acute inhalation toxicity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Definitions. The definitions in section 3 of TSCA and the definitions in 40 CFR Part 792—Good Laboratory... 40 CFR part 792, subpart f. (3) Test procedures—(i) Preparation. Healthy young adult animals are... at 40 CFR part 792, subpart J, the following specific information must be reported. The test...

  11. 40 CFR 799.9130 - TSCA acute inhalation toxicity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Definitions. The definitions in section 3 of TSCA and the definitions in 40 CFR Part 792—Good Laboratory... 40 CFR part 792, subpart f. (3) Test procedures—(i) Preparation. Healthy young adult animals are... at 40 CFR part 792, subpart J, the following specific information must be reported. The test...

  12. 40 CFR 799.9410 - TSCA chronic toxicity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... morphological (pathological) effects. (c) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part... requirements specified under EPA Good Laboratory Practice Standards at 40 CFR part 792, subpart J, the... equipment. The study must be conducted in compliance with 40 CFR Part 792—Good Laboratory Practice...

  13. 40 CFR 799.9410 - TSCA chronic toxicity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... morphological (pathological) effects. (c) Definitions. The definitions in section 3 of TSCA and in 40 CFR Part... requirements specified under EPA Good Laboratory Practice Standards at 40 CFR part 792, subpart J, the... equipment. The study must be conducted in compliance with 40 CFR Part 792—Good Laboratory Practice...

  14. 76 FR 38170 - Toxic Substances Control Act Chemical Testing; Receipt of Test Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... issue of March 16, 2006 (71 FR 13708) (FRL-7335-2). Section 4(d) of TSCA (15 U.S.C. 2603(d)) requires... Toxicity to Fish. 9. Acute Toxicity to Aquatic Invertebrates. 10. Toxicity to Aquatic Plants, e.g.,...

  15. 40 CFR 799.6784 - TSCA water solubility: Column elution method; shake flask method.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false TSCA water solubility: Column elution... AND MIXTURE TESTING REQUIREMENTS Product Properties Test Guidelines § 799.6784 TSCA water solubility... here may not yet be optimal. This method is intended for material with solubilities below...

  16. 40 CFR 799.6784 - TSCA water solubility: Column elution method; shake flask method.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false TSCA water solubility: Column elution... AND MIXTURE TESTING REQUIREMENTS Product Properties Test Guidelines § 799.6784 TSCA water solubility... here may not yet be optimal. This method is intended for material with solubilities below...

  17. 40 CFR 799.6784 - TSCA water solubility: Column elution method; shake flask method.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false TSCA water solubility: Column elution... AND MIXTURE TESTING REQUIREMENTS Product Properties Test Guidelines § 799.6784 TSCA water solubility... here may not yet be optimal. This method is intended for material with solubilities below...

  18. Stabilization/solidification of TSCA incinerator ash

    SciTech Connect

    Spence, R.D.; Trotter, D.R.; Francis, C.L.; Morgan, I.L.

    1994-06-01

    Stabilization/solidification is a well-known waste treatment technique that utilizes different additives and processes. The Phoenix Ash Technology of the Technical Innovation Development Engineering Company is such a technique that uses Cass C fly ash and mechanical pressure to make brick waste forms out of solid wastes, such as the bottom ash from the Toxic Substances Control Act incinerator at the Oak Ridge K-25 Site. One advantage of this technique is that no volume increase over the bulk volume of the bottom ash occurs. This technique should have the same high pH stabilization for Resource Conservation and Recovery Act metals as similar techniques. Also, consolidation of the bottom ash minimizes the potential problems of material dispersion and container corrosion. The bottom ash was spiked with {sup 99}{Tc} to test the effectiveness of the bricks as a physical barrier. The {sup 99}{Tc} leachability index measured for these bricks was 6.8, typical for the pertechnetate anion in cementitious waste forms, indicating that these bricks have accessible porosity as high as that of other cementitious waste forms, despite the mechanical compression, higher waste form density, and water resistant polymer coating.

  19. 40 CFR 799.9305 - TSCA Repeated dose 28-day oral toxicity study in rodents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply to this section. The... aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma glutamyl transpeptidase, and...

  20. 40 CFR 799.9305 - TSCA Repeated dose 28-day oral toxicity study in rodents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply to this section. The... aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma glutamyl transpeptidase, and...

  1. 40 CFR 799.9537 - TSCA in vitro mammalian chromosome aberration test.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply... after an S period of DNA replication, the nucleus does not go into mitosis but starts another S...

  2. 40 CFR 799.9537 - TSCA in vitro mammalian chromosome aberration test.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply... after an S period of DNA replication, the nucleus does not go into mitosis but starts another S...

  3. 40 CFR 799.9537 - TSCA in vitro mammalian chromosome aberration test.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply... after an S period of DNA replication, the nucleus does not go into mitosis but starts another S...

  4. 40 CFR 799.9537 - TSCA in vitro mammalian chromosome aberration test.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply... after an S period of DNA replication, the nucleus does not go into mitosis but starts another S...

  5. 40 CFR 799.9537 - TSCA in vitro mammalian chromosome aberration test.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... The definitions in section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply... after an S period of DNA replication, the nucleus does not go into mitosis but starts another S...

  6. 2003 HANFORD SITE TOXIC CHEMICAL RELEASE INVENTORY EMERGENCY PLANNING & COMMUNITY RIGHT TO KNOW ACT SECTION 313

    SciTech Connect

    ZALOUDEK, D.E.

    2004-06-16

    Pursuant to section 313 of the Emergency Planning and Community Right-To-Know Act of 1986 (EPCRA), and Executive Order 13148, ''Greening the Government Through Leadership in Environmental Management'', the U.S. Department of Energy has prepared and submitted a Toxic Chemical Release Inventory for the Hanford Site covering activities performed during calendar year 2003. EPCRA Section 313 requires facilities that manufacture, process, or otherwise use listed toxic chemicals in quantities exceeding established threshold levels to report total annual releases of those chemicals. During calendar year 2003, Hanford Site activities resulted in two chemicals used in amounts exceeding an activity threshold; ethylene glycol, Chemical Abstract Services Registry (CAS) Number 107-21-1 and lead, CAS Number 7439-92-1. Accordingly, the 2003 Hanford Site Toxic Chemical Release Inventory, DOE/RL-2004-20, includes total annual amounts of ethylene glycol and lead released to the environment, transferred to offsite locations, and otherwise managed as waste.

  7. 78 FR 69414 - Toxic Substances Control Act Chemical Testing; Receipt of Test Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... October 21, 2011 (76 FR 65385) (FRL-8885-5) (docket ID number EPA-HQ-OPPT-2009-0112). The table in this... AGENCY Toxic Substances Control Act Chemical Testing; Receipt of Test Data AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces EPA's receipt of test data on...

  8. 2001 Toxic Chemical Release Inventory Emergency Planning & Community Right to Know Act SEC 313

    SciTech Connect

    ZALOUDEK, D.E.

    2002-06-24

    Pursuant to section 313 of the Emergency Planning and Community Right-To-Know Act of 1986 (EPCRA), and Executive Order 13148, Greening the Government Through Leadership in Environmental Management, the US Department of Energy has prepared and submitted a Toxic Chemical Release Inventory for the Hanford Site covering activities performed during calendar year 2001. EPCRA Section 313 requires facilities that manufacture, process, or otherwise use listed toxic chemicals in quantities exceeding established threshold levels to report total annual releases of those chemicals. During calendar year 2001, Hanford Site activities resulted in one chemical used in amounts exceeding an activity threshold. Accordingly, the Hanford Site 2001 Toxic Chemical Release Inventory, DOE/RL-2002-37, includes total annual amount of lead released to the environment, transferred to offsite locations, and otherwise managed as waste.

  9. Development of structure-activity relationship rules for predicting carcinogenic potential of chemicals.

    PubMed

    Woo, Y T; Lai, D Y; Argus, M F; Arcos, J C

    1995-09-01

    Since the inception of Section 5 (Premanufacturing/Premarketing Notification, PMN) of the Toxic Substances Control Act (TSCA), structure-activity relationship (SAR) analysis has been effectively used by U.S. Environmental Protection Agency's (EPA) Structure Activity Team (SAT) in the assessment of potential carcinogenic hazard of new chemicals for which test data are not available. To capture, systematize and codify the Agency's predictive expertise in order to make it more widely available to assessors outside the TSCA program, a cooperative project was initiated to develop a knowledge rule-based expert system to mimic the thinking and reasoning of the SAT. In this communication, we describe the overall structure of this expert system, discuss the scientific bases and principles of SAR analysis of chemical carcinogens used in the development of SAR knowledge rules, and delineate the major factors/rules useful for assessing the carcinogenic potential of fibers, polymers, metals/metalloids and several major classes of organic chemicals. An integrative approach using available short-term predictive tests and non-cancer toxicological data to supplement SAR analysis has also been described. PMID:7570659

  10. [Physico-chemical profiling of centrally acting molecules for prediction of pharmacokinetic properties].

    PubMed

    Deák, Katalin

    2008-01-01

    Physico-chemical profiling is a fundamental tool at the early stage of drug discovery in screening drug-like candidates. Complex physico-chemical profiling, including molecular properties such as solubility, ionization, lipophilicity and permeability, has been found to be of predictive power in ADME (absorption, distribution, metabolism, elimination). In the present thesis work, the physico-chemical properties of centrally acting compounds were investigated. We determined the protonation constants (K), the partition coeffitient in octanol/water (Poct) and cyclohexane/water (Pch) systems of antidepressive sertraline and 15 antipsychotic piperidine and piperazine derivatives and calculated the delta logP (logPoct-logPch) values of the molecules. Due to the poor water solubility of the compounds potentiometry using the "co-solvent" technique was applied for the determination of the protonation constants. The logP values were measured by the dual-phase potentiometric titration in octanol/water system and the traditional shake-flask method was used in cyclohexane/water system. Highly precise physico-chemical data were obtained by these validated methods. The relationship between the structure of the molecules and the physico-chemical data was investigated. The pharmacokinetic properties of the compounds were predicted by the physico-chemical parameters. Linear relationship has been found between the brain penetration characterized by the logBB values and the delta logP values. The validity of the equation was controlled by the delta logP and the logBB values of sertraline. PMID:18986088

  11. 40 CFR 717.1 - Scope and compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ACT RECORDS AND REPORTS OF ALLEGATIONS THAT CHEMICAL SUBSTANCES CAUSE SIGNIFICANT ADVERSE REACTIONS TO... Substances Control Act (TSCA) requires manufacturers, processors, and distributors of chemical substances...

  12. 40 CFR 799.9305 - TSCA Repeated dose 28-day oral toxicity study in rodents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply to this section. The... concentration, erythrocyte count, total and differential leukocyte count, platelet count and a measure of blood clotting time/potential. (ii) Blood samples should be taken from a named site just prior to or as part...

  13. 40 CFR 799.9305 - TSCA Repeated dose 28-day oral toxicity study in rodents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... section 3 of TSCA and in 40 CFR Part 792—Good Laboratory Practice Standards apply to this section. The... concentration, erythrocyte count, total and differential leukocyte count, platelet count and a measure of blood clotting time/potential. (ii) Blood samples should be taken from a named site just prior to or as part...

  14. 75 FR 58377 - Lead in Ammunition and Fishing Sinkers; Disposition of TSCA Section 21 Petition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... AGENCY Lead in Ammunition and Fishing Sinkers; Disposition of TSCA Section 21 Petition AGENCY... section 6(a) the manufacture, processing, and distribution in commerce of (1) lead bullets and shot; and (2) lead fishing sinkers. On August 27, 2010, EPA denied the first request due to a lack of...

  15. 75 FR 70246 - Lead Fishing Sinkers; Disposition of TSCA Section 21 Petition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Lead in Bullets and Shot As discussed in the Federal Register of September 24, 2010 (75 FR 58377) (FRL... one the Agency, as reflected in its proposal, found to be appropriate even then. (59 FR 11122, March 9... AGENCY Lead Fishing Sinkers; Disposition of TSCA Section 21 Petition AGENCY: Environmental...

  16. 40 CFR 799.6786 - TSCA water solubility: Generator column method.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false TSCA water solubility: Generator...: Generator column method. (a) Scope—(1) Applicability. This section is intended to meet the testing... the saturated solutions produced by the generator column. After extraction onto a...

  17. 40 CFR 799.6786 - TSCA water solubility: Generator column method.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false TSCA water solubility: Generator...: Generator column method. (a) Scope—(1) Applicability. This section is intended to meet the testing... the saturated solutions produced by the generator column. After extraction onto a...

  18. 40 CFR 799.6786 - TSCA water solubility: Generator column method.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false TSCA water solubility: Generator...: Generator column method. (a) Scope—(1) Applicability. This section is intended to meet the testing... the saturated solutions produced by the generator column. After extraction onto a...

  19. Advances in Exposure Science (Washington, DC Modernized TSCA meeting)

    EPA Science Inventory

    I am describing current research from the Chemical Safety for Sustainability research program's Rapid Exposure and Dosimetry project that relates to predicting human exposure to environmental chemicals for thousands of chemicals.

  20. Request for interim approval to operate Trench 94 of the 218-E-12B Burial Ground as a chemical waste landfill for disposal of polychlorinated biphenyl waste in submarine reactor compartments. Revision 2

    SciTech Connect

    Cummins, G.D.

    1994-06-01

    This request is submitted to seek interim approval to operate a Toxic Substances Control Act (TSCA) of 1976 chemical waste landfill for the disposal of polychlorinated biphenyl (PCB) waste. Operation of a chemical waste landfill for disposal of PCB waste is subject to the TSCA regulations of 40 CFR 761. Interim approval is requested for a period not to exceed 5 years from the date of approval. This request covers only the disposal of small 10 quantities of solid PCB waste contained in decommissioned, defueled submarine reactor compartments (SRC). In addition, the request applies only to disposal 12 of this waste in Trench 94 of the 218-E-12B Burial Ground (Trench 94) in the 13 200 East Area of the US Department of Energy`s (DOE) Hanford Facility. Disposal of this waste will be conducted in accordance with the Compliance 15 Agreement (Appendix H) between the DOE Richland Operations Office (DOE-RL) and 16 the US Environmental Protection Agency (EPA), Region 10. During the 5-year interim approval period, the DOE-RL will submit an application seeking final 18 approval for operation of Trench 94 as a chemical waste landfill, including 19 any necessary waivers, and also will seek a final dangerous waste permit from 20 the Washington State Department of Ecology (Ecology) for disposal of lead 21 shielding contained in the SRCS.

  1. 40 CFR 799.9510 - TSCA bacterial reverse mutation test.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... chemical classes that include short chain aliphatic nitrosamines, divalent metals, aldehydes, azo-dyes and... solvent/vehicle should not be suspected of chemical reaction with the test substance and shall...

  2. 40 CFR 799.9510 - TSCA bacterial reverse mutation test.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... chemical classes that include short chain aliphatic nitrosamines, divalent metals, aldehydes, azo-dyes and... solvent/vehicle should not be suspected of chemical reaction with the test substance and shall...

  3. 40 CFR 799.9510 - TSCA bacterial reverse mutation test.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... chemical classes that include short chain aliphatic nitrosamines, divalent metals, aldehydes, azo-dyes and... solvent/vehicle should not be suspected of chemical reaction with the test substance and shall...

  4. 77 FR 22707 - Electronic Reporting Under the Toxic Substances Control Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... Regulatory Review'' (76 FR 3821, January 21, 2011). EPA has prepared an economic analysis of this action.... EPA. Electronic Toxic Control Act (eTSCA)/e-PMN Reporting Tool User's Guide. 7. EPA. Economic Analysis... submitters would ultimately exceed the transition costs (see Economic Analysis referenced in Unit IV.)....

  5. 1992 Toxic Chemical Release Inventory: Emergency Planning and Community Right-To-Know-Act of 1986 Section 313

    SciTech Connect

    Not Available

    1993-07-01

    Section 313 of the Emergency Planning and Community Right-To-Know Act of 1986 (EPCRA) requires the annual submittal of toxic chemical release information to the US Environmental Protection Agency (EPA). The following document is the July 1993 submittal of the EPCRA Toxic Chemical Release Inventory Report (Form R). Included is a Form R for chlorine and for lead, the two chemicals used in excess of the established regulatory thresholds at the Hanford Site by the US Department of Energy, Richland Operations Office and its contractors during calendar year 1992.

  6. 40 CFR 711.6 - Chemical substances for which information is not required.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) developed under the procedures of 40 CFR part 790, or is the subject of an order issued under TSCA section 5... living organism, and that meets the definition of microorganism at 40 CFR 725.3. Any chemical substance... occurring chemical substances. Any naturally occurring chemical substance, as described in 40 CFR...

  7. 78 FR 1856 - Availability of Draft Chemical Risk Assessments; Public Comment Opportunity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... AGENCY Availability of Draft Chemical Risk Assessments; Public Comment Opportunity AGENCY: Environmental... and opening the 60-day public comment period for several draft chemical risk assessments. These draft risk assessments address five of the initial seven chemicals from the Agency's TSCA Work...

  8. A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus.

    PubMed

    Vogs, Carolina; Kühnert, Agnes; Hug, Christine; Küster, Eberhard; Altenburger, Rolf

    2015-01-01

    The toxic potency of chemicals is determined by using the internal effect concentration by accounting for differences in toxicokinetic processes and mechanisms of toxic action. The present study examines toxicokinetics of specifically acting and reactive chemicals in the green algae Scenedesmus vacuolatus by using an indirect method. Concentration depletion in the exposure medium was measured for chemicals of lower (log KOW  < 3: isoproturon, metazachlor, paraquat) and moderate (log KOW 4-5: irgarol, triclosan, N-phenyl-2-naphthylamine) hydrophobicity at 7 to 8 time points over 240 min or 360 min. Uptake and overall elimination rates were estimated by fitting a toxicokinetic model to the observed concentration depletions. The equilibrium of exposure concentrations was reached within minutes to hours or was even not observed within the exposure time. The kinetics of bioconcentration cannot be explained by the chemical's hydrophobicity only, but influential factors such as ionization of chemicals, the ion trapping mechanism, or the potential susceptibility for biotransformation are discussed. Internal effect concentrations associated with 50% inhibition of S. vacuolatus reproduction were predicted by linking the bioconcentration kinetics to the effect concentrations and ranged from 0.0480 mmol/kg wet weight to 7.61 mmol/kg wet weight for specifically acting and reactive chemicals. Knowing the time-course of the internal effect concentration may promote an understanding of toxicity processes such as delayed toxicity, carry-over toxicity, or mixture toxicity in future studies. PMID:25263251

  9. Title III list of lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and section 112(r) of the Clean Air Act, as amended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990

    SciTech Connect

    Not Available

    1994-06-01

    The consolidated chemical list includes chemicals subject to reporting requirements under Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), also known as the Emergency Planning and Community Right-to-Know Act (EPCRA), and chemicals listed under section 112(r) of Title III the Clean Air Act (CAA) Amendments of 1990. This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 313 of SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. Separate lists are also provided of Resource Conservation and Recovery Act (RCRA) waste streams and unlisted hazardous wastes, and of radionuclides reportable under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). These lists should be used as reference tool, not as a definitive source of compliance information. The chemicals on the consolidated list are ordered by Chemical Abstract Service (CAS) registry number. Categories of chemicals, which do not have CAS registry numbers, but which are cited under CERCLA, EPCRA section 313, and the CAA, are placed at the end of the list. More than one chemical name may be listed for one CAS number, because the same chemical may appear on different lists under different names.

  10. 75 FR 47589 - Agency Information Collection Activities; Proposed Collection; Comment Request; Correction of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... Misreported Chemical Substances on the TSCA Inventory; EPA ICR No. 1741.06, OMB Control No. 2070-0145 AGENCY... Control Act (TSCA) Inventory and regulated under TSCA section 8, who had reported to the initial effort to... substances. EPA has developed guidelines (45 FR 50544, July 29, 1980) under which incorrectly...

  11. Chemical distribution facilities: Section 313 of the Emergency Planning and Community Right-to-Know Act. Toxic chemical release inventory

    SciTech Connect

    1999-01-01

    This document is intended to assist establishments and facilities designated by the Standard Industrial Classification (SIC) code 5169 (chemical and allied products wholesale) in making compliance determinations under the EPCRA Section 313 reporting requirements and preparing Form R(s) or the Form A certification statement(s) as required. The EPCRA Section 313 program is commonly referred to as the Toxic Chemical Release Inventory (TRI) program. This document is organized to provide a step-by-step guide to compliance with EPCRA Section 313, starting with how you determine if your facility must report through completion of the Form R or Form A.

  12. 2008 Toxic Chemical Release Inventory 2008 Toxic Chemical Release Inventory Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    Ecology and Air Quality Group

    2009-10-01

    For reporting year 2008, Los Alamos National Laboratory (LANL) submitted a Form R report for lead as required under the Emergency Planning and Community Right-to- Know Act (EPCRA) Section 313. No other EPCRA Section 313 chemicals were used in 2008 above the reportable thresholds. This document was prepared to provide a description of the evaluation of EPCRA Section 313 chemical use and threshold determinations for LANL for calendar year 2008, as well as to provide background information about data included on the Form R reports. Section 313 of EPCRA specifically requires facilities to submit a Toxic Chemical Release Inventory Report (Form R) to the U.S. Environmental Protection Agency (EPA) and state agencies if the owners and operators manufacture, process, or otherwise use any of the listed toxic chemicals above listed threshold quantities. EPA compiles this data in the Toxic Release Inventory database. Form R reports for each chemical over threshold quantities must be submitted on or before July 1 each year and must cover activities that occurred at the facility during the previous year. In 1999, EPA promulgated a final rule on persistent bioaccumulative toxics (PBTs). This rule added several chemicals to the EPCRA Section 313 list of toxic chemicals and established lower reporting thresholds for these and other PBT chemicals that were already reportable. These lower thresholds became applicable in reporting year 2000. In 2001, EPA expanded the PBT rule to include a lower reporting threshold for lead and lead compounds. Facilities that manufacture, process, or otherwise use more than 100 lb of lead or lead compounds must submit a Form R.

  13. Title III List of Lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and Section 112(r) of the Clean Air Act, as amended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990

    SciTech Connect

    1996-12-01

    This consolidated chemical list includes chemicals subject to reporting requirements under Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), also known as the Emergency Planning and Community Right-to-Know Act (EPCRA) and chemicals listed under Section 112(r) of Title III of the Clean Air Act (CAA) Amendments of 1990. This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 314 or SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. It also will also help firms determine whether they will be subject to accident prevention regulations under CAA section 112(r).

  14. 75 FR 57169 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... Register of April 24, 1990 (55 FR 17376). Consult that preamble for further information on the objectives.../chemical properties of the PMN substance, as described in the New Chemical Program's PBT category (64 FR... includes one PMN substance (P-04-269) that is subject to a ``risk-based'' consent order under TSCA...

  15. 75 FR 42441 - Sixty-Sixth Report of the TSCA Interagency Testing Committee to the Administrator of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... Federal Register issue of February 25, 2010 (75 FR 8575) (FRL-8805-8) available on-line at http://www.gpoaccess.gov/fr . III. The TSCA Interagency Testing Committee Statutory Organizations and Their... Recommended (mixed isomers) 41 November 1997 Phenol, 4-(1,1,3,3- Recommended tetramethylbutyl)- 55...

  16. 1993 Toxic Chemical Release Inventory: Emergency Planning and Community Right-To-Know Act of 1986, Section 313

    SciTech Connect

    Not Available

    1994-07-01

    Section 313 of the Emergency Planning and Community Right-To-Know-Act of 1986 (EPCRA) requires the annual submittal of toxic chemical release information to the US Environmental Protection Agency. The following document is the July 1994 submittal of the Hanford site EPCRA Toxic Chemical Release Inventory (TRI) Report. Included is a Form R for chlorine, the sole chemical used in excess of the established regulatory thresholds at the Hanford Site by the US Department of Energy, Richland Operations Office and its contractors during Calendar Year 1993. Only those facilities that fall within the Standard Industrial Classification (SIC) code range of 20 through 39 are subject to mandatory reporting under EPCRA, Section 313. However, on August 3, 1993, Executive Order 12856 was signed, requiring all federal agencies and facilities to comply with pollution prevention and emergency planning and community right-to-know provisions established by Section 313 of EPCRA and Section 6607 of the Pollution Prevention Act of 1990, without restriction to the specified SIC Codes. The report format requires identification of the facility SIC Code in the TRI Report. Application of definitions and requirements provided in Title 40, Code of Federal Regulations Part 372.22 has led to the adoption of SIC Code 9999, Nonclassifiable Establishments, as the primary Hanford Site SIC Code for EPCRA regulatory assessments. The SIC Code 9999 determination is based on a broad analysis of the current mission of the Hanford Site which includes environmental and waste management, demonstration and application of advanced remediation technologies, and environmental restoration.

  17. 1997 toxic chemical release inventory -- Emergency Planning and Community Right-To-Know Act, Section 313

    SciTech Connect

    Zaloudek, D.E.

    1998-06-30

    Two listed toxic chemicals were used at the Hanford Site above established activity thresholds: phosphoric acid and chlorine. Because total combined quantities of chlorine released, disposed, treated, recovered through recycle operations, co-combusted for energy recovery, and transferred to off-site locations for the purpose of recycle, energy recovery, treatment, and/or disposal, amounted to less than 500 pounds, the Hanford Site qualified for the alternate one million pound threshold for chlorine. Accordingly, this Toxic Chemical Release Inventory includes a Form A for chlorine, and a Form B for phosphoric acid.

  18. Toxic chemical release inventory: Superfund Amendments Reauthorization Act, Title 3, Section 313

    SciTech Connect

    Not Available

    1989-07-01

    Toxic chemical release information contained in this document was derived using process flow diagrams and material balances, process chemistry and emissions treatment technology, hazardous materials inventories, environmental permits, hazardous materials release reports, hazardous waste shipment papers, and sample analysis or monitoring data where available.

  19. 77 FR 71561 - Health and Safety Data Reporting; Addition of Certain Chemicals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ...This final rule requires manufacturers (including importers) of cadmium or cadmium compounds, including as part of an article, that have been, or are reasonably likely to be, incorporated into consumer products to report certain unpublished health and safety studies to EPA. The Interagency Testing Committee (ITC), established under section 4(e) of the Toxic Substances Control Act (TSCA) to......

  20. Roadmaps to sources of information on chemicals listed in the Emergency Planning Community and Community Right-To-Know Act also known as SARA (Superfund Amendments and Reauthorization Act) Title III, Section 313. Toxic Release Inventory (for microcomputers). Data file

    SciTech Connect

    Leitzke, J.; Edelstein, M.

    1989-07-14

    EPA has developed a database of sources of information on the chemicals listed in Section 313 of the Emergency Preparedness Community Right-To-Know Act, Title III of the Superfund Amendments and Reauthorization Act. The database is intended to assist users of Section 313 Toxic Release Inventory data to perform exposure and risk assessments of these chemicals. The Roadmaps system displays and/or prints out information for the Section 313 chemicals on health and environmental effects, Federal Regulation, and state air and water regulations, monitoring data, and state contacts.

  1. 75 FR 3462 - Claims of Confidentiality of Certain Chemical Identities Submitted under Section 8(e) of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... AGENCY Claims of Confidentiality of Certain Chemical Identities Submitted under Section 8(e) of the Toxic... announcing a new general practice of reviewing submissions under section 8(e) of the Toxic Substances Control... section 8(e) of TSCA involves a chemical identity that is already listed on the public portion of the...

  2. Recovery Act: Novel Oxygen Carriers for Coal-fueled Chemical Looping

    SciTech Connect

    Pan, Wei-Ping; Cao, Yan

    2012-11-30

    Chemical Looping Combustion (CLC) could totally negate the necessity of pure oxygen by using oxygen carriers for purification of CO{sub 2} stream during combustion. It splits the single fuel combustion reaction into two linked reactions using oxygen carriers. The two linked reactions are the oxidation of oxygen carriers in the air reactor using air, and the reduction of oxygen carriers in the fuel reactor using fuels (i.e. coal). Generally metal/metal oxides are used as oxygen carriers and operated in a cyclic mode. Chemical looping combustion significantly improves the energy conversion efficiency, in terms of the electricity generation, because it improves the reversibility of the fuel combustion process through two linked parallel processes, compared to the conventional combustion process, which is operated far away from its thermo-equilibrium. Under the current carbon-constraint environment, it has been a promising carbon capture technology in terms of fuel combustion for power generation. Its disadvantage is that it is less mature in terms of technological commercialization. In this DOE-funded project, accomplishment is made by developing a series of advanced copper-based oxygen carriers, with properties of the higher oxygen-transfer capability, a favorable thermodynamics to generate high purity of CO{sub 2}, the higher reactivity, the attrition-resistance, the thermal stability in red-ox cycles and the achievement of the auto-thermal heat balance. This will be achieved into three phases in three consecutive years. The selected oxygen carriers with final-determined formula were tested in a scaled-up 10kW coal-fueled chemical looping combustion facility. This scaled-up evaluation tests (2-day, 8-hour per day) indicated that, there was no tendency of agglomeration of copper-based oxygen carriers. Only trace-amount of coke or carbon deposits on the copper-based oxygen carriers in the fuel reactor. There was also no evidence to show the sulphidization of oxygen

  3. Title III list of lists: Consolidated list of chemicals subject to the Emergency Planning and Community Right-to-Know Act (EPCRA) and section 112(r) of the Clean Air Act, as ammended. Title III of the Superfund Amendments and Reauthorization Act of 1986, and Title III of the Clean Air Act Amendments of 1990, April 1995

    SciTech Connect

    1995-04-01

    This consolidated list has been prepared to help firms handling chemicals determine whether they need to submit reports under sections 302, 304, or 313 of SARA Title III (EPCRA) and, for a specific chemical, what reports may need to be submitted. It will also help firms determine whether they will be subject to accident prevention regulations under CAA section 112(r). Separate lists are also provided of Resource Conservation and Recovery Act (RCRA) waste streams and unlisted hazardous wastes, and of radionuclides reportable under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). These lists should be used as a reference tool, not as a definitive source of compliance information.

  4. 77 FR 15609 - Revocation of TSCA Section 4 Testing Requirements for Certain High Production Volume Chemical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... Register (71 FR 13708, March 16, 2006) (FRL-7335-2). (Document ID number EPA-HQ-OPPT-2005-0033-0001). 2..., Substantial Release, and Substantial or Significant Human Exposure; Notice. Federal Register (58 FR 28736, May... regulatory action'' under Executive Order 12866, entitled ``Regulatory Planning and Review'' (58 FR...

  5. 40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... claim of confidentiality only to the extent permitted by section 14 of TSCA and 40 CFR part 2, subpart B... water treatment chemicals to prevent unreasonable risks associated with human exposure to air emissions... chromium air emissions increases the risk of lung cancer. Federal Law prohibits use of this substance...

  6. 40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... claim of confidentiality only to the extent permitted by section 14 of TSCA and 40 CFR part 2, subpart B... water treatment chemicals to prevent unreasonable risks associated with human exposure to air emissions... chromium air emissions increases the risk of lung cancer. Federal Law prohibits use of this substance...

  7. 40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... claim of confidentiality only to the extent permitted by section 14 of TSCA and 40 CFR part 2, subpart B... water treatment chemicals to prevent unreasonable risks associated with human exposure to air emissions... chromium air emissions increases the risk of lung cancer. Federal Law prohibits use of this substance...

  8. 40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... claim of confidentiality only to the extent permitted by section 14 of TSCA and 40 CFR part 2, subpart B... water treatment chemicals to prevent unreasonable risks associated with human exposure to air emissions... chromium air emissions increases the risk of lung cancer. Federal Law prohibits use of this substance...

  9. 77 FR 4947 - Proposed Significant New Use Rules on Certain Chemical Substances; Reopening of Comment Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... in the Federal Register of December 28, 2011 (76 FR 81447) (FRL-9326-2). In that document, EPA...: Kenneth Moss, Chemical Control Division (7405M), Office of Pollution Prevention and Toxics, Environmental...; email address: moss.kenneth@epa.gov . For general information contact: The TSCA-Hotline,...

  10. 40 CFR 749.68 - Hexavalent chromium-based water treatment chemicals in cooling systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... water treatment chemicals to prevent unreasonable risks associated with human exposure to air emissions... municipality; any interstate body; and any department, agency, or instrumentality of the Federal Government... claim of confidentiality only to the extent permitted by section 14 of TSCA and 40 CFR part 2, subpart...

  11. Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

    PubMed Central

    2013-01-01

    Background In mammals, ABCB1 constitutes a cellular “first line of defense” against a wide array of chemicals and drugs conferring cellular multidrug or multixenobiotic resistance (MDR/MXR). We tested the hypothesis that an ABCB1 ortholog serves as protection for the sensitive developmental processes in zebrafish embryos against adverse compounds dissolved in the water. Results Indication for ABCB1-type efflux counteracting the accumulation of chemicals in zebrafish embryos comes from experiments with fluorescent and toxic transporter substrates and inhibitors. With inhibitors present, levels of fluorescent dyes in embryo tissue and sensitivity of embryos to toxic substrates were generally elevated. We verified two predicted sequences from zebrafish, previously annotated as abcb1, by cloning; our synteny analyses, however, identified them as abcb4 and abcb5, respectively. The abcb1 gene is absent in the zebrafish genome and we explored whether instead Abcb4 and/or Abcb5 show toxicant defense properties. Quantitative real-time polymerase chain reaction (qPCR) analyses showed the presence of transcripts of both genes throughout the first 48 hours of zebrafish development. Similar to transporter inhibitors, morpholino knock-down of Abcb4 increased accumulation of fluorescent substrates in embryo tissue and sensitivity of embryos toward toxic compounds. In contrast, morpholino knock-down of Abcb5 did not exert this effect. ATPase assays with recombinant protein obtained with the baculovirus expression system confirmed that dye and toxic compounds act as substrates of zebrafish Abcb4 and inhibitors block its function. The compounds tested comprised model substrates of human ABCB1, namely the fluorescent dyes rhodamine B and calcein-am and the toxic compounds vinblastine, vincristine and doxorubicin; cyclosporin A, PSC833, MK571 and verapamil were applied as inhibitors. Additionally, tests were performed with ecotoxicologically relevant compounds: phenanthrene (a

  12. Common synonyms: For chemicals listed under section 313 of the Emergency Planning and Community Right-to-Know Act, March 1995

    SciTech Connect

    1995-03-01

    This glossary contains chemical names and synonyms for substances covered by the reporting requirements of section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA) (Title III of the Superfund Amendments and Reauthorization Act (SARA)) (40 CFR Part 372). Part I is a listing in Chemical Abstracts Service (CAS) registry number order. The CAS number is followed by the name by which the chemical is listed under section 313. Chemicals should be reported to TRI by their listing names. Each CAS number and associated listing name is followed by synonyms in alphabetical order. Part II of the glossary is an alphabetical list of chemical names and synonyms, with CAS numbers. In this list, section 313 names are followed by an asterisk and are footnoted as listing names.

  13. 1997 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    Heather McBride

    1997-07-01

    The Emergency Planning and Community Right-to-Know Act of 1986 (EPCIL4), Title III, Section 313 [also known as the Superfund Amendment and Reauthorization Act (SARA)], as modified by Executive Order 12856, requires all federal facilities to submit an annual Toxic Chemical Release Inventory report every July for the preceding calendar year. Owners and operators of manufacturing, processing, or production facilities are required to report their toxic chemical releases to all environmental mediums (air, water, soil, etc.). At Los Alamos National Laboratory (LANL), nitric acid was the only toxic chemical used in 1997 that met the reportable threshold limit of 10,000 lb. Form R is the only documentation required by the Environmental Protection Agency, and it is included in the appendix of this report. This report, as requested by DOE, is provided for documentation purposes. In addition, a detailed description of the evaluation and reporting process for chemicals and processes at LANL has been included.

  14. Chemical Safety Improvement Act

    THOMAS, 113th Congress

    Sen. Lautenberg, Frank R. [D-NJ

    2013-05-22

    02/04/2014 Committee on Environment and Public Works Subcommittee on Water and Wildlife. Hearings held. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. Secure Chemical Facilities Act

    THOMAS, 113th Congress

    Sen. Lautenberg, Frank R. [D-NJ

    2013-01-23

    01/23/2013 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. Secure Chemical Facilities Act

    THOMAS, 112th Congress

    Sen. Lautenberg, Frank R. [D-NJ

    2011-03-31

    03/31/2011 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  17. Results of Hazardous and Mixed Waste Excavation from the Chemical Waste Landfill

    SciTech Connect

    Young, S. G.; Schofield, D. P.; Kwiecinski, D.; Edgmon, C. L.; Methvin, R.

    2002-02-27

    This paper describes the results of the excavation of a 1.9-acre hazardous and mixed waste landfill operated for 23 years at Sandia National Laboratories, Albuquerque, New Mexico. Excavation of the landfill was completed in 2 1/2 years without a single serious accident or injury. Approximately 50,000 cubic yards of soil contaminated with volatile and semi-volatile organics, metals, polychlorinated biphenyl compounds, and radioactive constituents was removed. In addition, over 400 cubic yards of buried debris was removed, including bulk debris, unknown chemicals, compressed gas cylinders, thermal and chemical batteries, explosive and ordnance debris, pyrophoric materials and biohazardous waste. Removal of these wastes included negotiation of multiple regulations and guidances encompassed in the Resource Conservation and Recovery Act (RCRA), the Toxic Substances Control Act (TSCA), and risk assessment methodology. RCRA concepts that were addressed include the area of contamination, permit modification, emergency treatment provision, and listed waste designation. These regulatory decisions enabled the project to overcome logistical and programmatic needs such as increased operational area, the ability to implement process improvements while maintaining a record of decisions and approvals.

  18. 1998 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III

    SciTech Connect

    Marjorie B. Stockton

    1999-11-01

    The Emergency Planning and Community Right-to-Know Act (EPCRA) of 1986 [also known as the Superfund Amendment and Reauthorization Act (SARA), Title III], as modified by Executive Order 12856, requires that all federal facilities evaluate the need to submit an annual Toxic Chemical Release Inventory report as prescribed in Title III, Section 313 of this Act. This annual report is due every July for the preceding calendar year. Owners and operators who manufacture, process, or otherwise use certain toxic chemicals above listed threshold quantities are required to report their toxic chemical releases to all environmental mediums (air, water, soil, etc.). At Los Alamos National Laboratory (LANL), no EPCRA Section 313 chemicals were used in 1998 above the reportable threshold limits of 10,000 lb or 25,000 lb. Therefore LANL was not required to submit any Toxic Chemical Release Inventory reports (Form Rs) for 1998. This document was prepared to provide a detailed description of the evaluation on chemical usage and EPCRA Section 313 threshold determinations for LANL for 1998.

  19. 77 FR 69824 - Certain New Chemicals; Receipt and Status Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... required by TSCA section 5 to provide EPA with a PMN, before initiating the activity. Section 5(h)(1) of............ (S) Fragrance (S) 2- ingredient. octenenitrile,3,5,7- trimethyl-. P-13-0013 10/5/2012 1/2/2013 Dow Chemical (G) Open-non dispersive (G) Polyurethane Company. use. polymer. P-13-0014 10/8/2012 1/5/2013...

  20. Cheminformatics and Computational Chemistry: A Powerful Combination for the Encoding of Process Science

    EPA Science Inventory

    The registration of new chemicals under the Toxicological Substances Control Act (TSCA) and new pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires knowledge of the process science underlying the transformation of organic chemicals in natural...

  1. Cheminformatics Applications and Physicochemical Property Calculators: A Powerful Combination for the Encoding of Process Science

    EPA Science Inventory

    The registration of new chemicals under the Toxic Substances Control Act (TSCA) and new pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires knowledge of the process science underlying the transport and transformation of organic chemicals in n...

  2. 1992 Tier Two emergency and hazardous chemical inventory. Emergency Planning and Community Right-To-Know Act, Section 312

    SciTech Connect

    Not Available

    1993-03-01

    This report is a compilation of data on emergency and hazardous chemicals stored at the Hanford Reservation. The report lists name or chemical description, physical and health hazards, inventories and storage location.

  3. 2009 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    Environmental Stewardship Group

    2010-11-01

    For reporting year 2009, Los Alamos National Laboratory (LANL) submitted a Form R report for lead as required under the Emergency Planning and Community Right-to- Know Act (EPCRA) Section 313. No other EPCRA Section 313 chemicals were used in 2009 above the reportable thresholds. This document was prepared to provide a description of the evaluation of EPCRA Section 313 chemical use and threshold determinations for LANL for calendar year 2009, as well as to provide background information about data included on the Form R reports.

  4. Use of QSAR validation principles to enhance predictive approaches in the US EPA ECOSAR model

    EPA Science Inventory

    The US EPA Office of Pollution Prevention and Toxics (OPPT) is responsible for implementing the Toxic Substances Control Act (TSCA). TSCA is the US law that regulates industrial chemicals in the US and OPPT evaluates both new chemicals entering commerce, as well as those chemica...

  5. Pollution prevention opportunity assessment for the K-25 Site Toxic Substances Control Act Incinerator Operations, Level III

    SciTech Connect

    1995-09-01

    A Level III pollution prevention opportunity assessment (PPOA) was performed for the Oak Ridge K-25 Site Toxic Substances Control Act (TSCA) Incinerator to evaluate pollution prevention (P2) options for various waste streams: The main objective of this study was to identify and evaluate options to reduce the quantities of each waste stream generated by the TSCA Incinerator operations to realize significant environmental and/or economic benefits from P2. For each of the waste streams, P2 options were evaluated following the US Environmental Protection Agency (EPA) hierarchy to (1) reduce the quantity of waste generated, (2) recycle the waste, and/or (3) use alternate waste treatment or segregation methods. This report provides process descriptions, identification and evaluation of P2 options, and final recommendations.

  6. 2002 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    M. Stockton

    2003-11-01

    For reporting year 2002, Los Alamos National Laboratory (LANL or the Laboratory) submitted Form R reports for lead compounds and mercury as required under the Emergency Planning and Community Right-to-Know Act (EPCRA), Section 313. No other EPCRA Section 313 chemicals were used in 2002 above the reportable thresholds. This document was prepared to provide a description of the evaluation of EPCRA Section 313 chemical usage and threshold determinations for LANL for calendar year 2002 as well as provide background information about the data included on the Form R reports. Section 313 of EPCRA specifically requires facilities to submit a Toxic Chemical Release Inventory report (Form R) to the U.S. Environmental Protection Agency (EPA) and state agencies if the owners and operators manufacture, process, or otherwise use any of the listed toxic chemicals above listed threshold quantities. EPA compiles this data in the Toxic Release Inventory database. Form R reports for each chemical over threshold quantities must be submitted on or before July 1 each year and must cover activities that occurred at the facility during the previous year. In 1999 EPA promulgated a final rule on Persistent Bioaccumulative Toxics (PBTs). This rule added several chemicals to the EPCRA Section 313 list of toxic chemicals and established lower reporting thresholds for these and other PBT chemicals that were already reportable under EPCRA Section 313. These lower thresholds became applicable in reporting year 2000. In 2001, EPA expanded the PBT rule to include a lower reporting threshold for lead and lead compounds. Facilities that manufacture, process, or otherwise use more than 100 lb of lead or lead compounds must submit a Form R.

  7. In silico identification and pharmacological evaluation of novel endocrine disrupting chemicals that act via the ligand-binding domain of the estrogen receptor α.

    PubMed

    McRobb, Fiona M; Kufareva, Irina; Abagyan, Ruben

    2014-09-01

    Endocrine disrupting chemicals (EDCs) pose a significant threat to human health, society, and the environment. Many EDCs elicit their toxic effects through nuclear hormone receptors, like the estrogen receptor α (ERα). In silico models can be used to prioritize chemicals for toxicological evaluation to reduce the amount of costly pharmacological testing and enable early alerts for newly designed compounds. However, many of the current computational models are overly dependent on the chemistry of known modulators and perform poorly for novel chemical scaffolds. Herein we describe the development of computational, three-dimensional multi-conformational pocket-field docking, and chemical-field docking models for the identification of novel EDCs that act via the ligand-binding domain of ERα. These models were highly accurate in the retrospective task of distinguishing known high-affinity ERα modulators from inactive or decoy molecules, with minimal training. To illustrate the utility of the models in prospective in silico compound screening, we screened a database of over 6000 environmental chemicals and evaluated the 24 top-ranked hits in an ERα transcriptional activation assay and a differential scanning fluorimetry-based ERα binding assay. Promisingly, six chemicals displayed ERα agonist activity (32nM-3.98μM) and two chemicals had moderately stabilizing effects on ERα. Two newly identified active compounds were chemically related β-adrenergic receptor (βAR) agonists, dobutamine, and ractopamine (a feed additive that promotes leanness in cattle and poultry), which are the first βAR agonists identified as activators of ERα-mediated gene transcription. This approach can be applied to other receptors implicated in endocrine disruption. PMID:24928891

  8. In Silico Identification and Pharmacological Evaluation of Novel Endocrine Disrupting Chemicals That Act via the Ligand-Binding Domain of the Estrogen Receptor α

    PubMed Central

    Kufareva, Irina; Abagyan, Ruben

    2014-01-01

    Endocrine disrupting chemicals (EDCs) pose a significant threat to human health, society, and the environment. Many EDCs elicit their toxic effects through nuclear hormone receptors, like the estrogen receptor α (ERα). In silico models can be used to prioritize chemicals for toxicological evaluation to reduce the amount of costly pharmacological testing and enable early alerts for newly designed compounds. However, many of the current computational models are overly dependent on the chemistry of known modulators and perform poorly for novel chemical scaffolds. Herein we describe the development of computational, three-dimensional multi-conformational pocket-field docking, and chemical-field docking models for the identification of novel EDCs that act via the ligand-binding domain of ERα. These models were highly accurate in the retrospective task of distinguishing known high-affinity ERα modulators from inactive or decoy molecules, with minimal training. To illustrate the utility of the models in prospective in silico compound screening, we screened a database of over 6000 environmental chemicals and evaluated the 24 top-ranked hits in an ERα transcriptional activation assay and a differential scanning fluorimetry-based ERα binding assay. Promisingly, six chemicals displayed ERα agonist activity (32nM–3.98μM) and two chemicals had moderately stabilizing effects on ERα. Two newly identified active compounds were chemically related β-adrenergic receptor (βAR) agonists, dobutamine, and ractopamine (a feed additive that promotes leanness in cattle and poultry), which are the first βAR agonists identified as activators of ERα-mediated gene transcription. This approach can be applied to other receptors implicated in endocrine disruption. PMID:24928891

  9. 2006 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    Ecology and Air Quality Group

    2007-12-12

    For reporting year 2006, Los Alamos National Laboratory (LANL or the Laboratory) submitted Form R reports for lead as required under the Emergency Planning and Community Right-to-Know Act (EPCRA) Section 313. No other EPCRA Section 313 chemicals were used in 2006 above the reportable thresholds. This document was prepared to provide a description of the evaluation of EPCRA Section 313 chemical use and threshold determinations for LANL for calendar year 2006, as well as to provide background information about data included on the Form R reports. Section 313 of EPCRA specifically requires facilities to submit a Toxic Chemical Release Inventory Report (Form R) to the U.S. Environmental Protection Agency (EPA) and state agencies if the owners and operators manufacture, process, or otherwise use any of the listed toxic chemicals above listed threshold quantities. EPA compiles this data in the Toxic Release Inventory database. Form R reports for each chemical over threshold quantities must be submitted on or before July 1 each year and must cover activities that occurred at the facility during the previous year. In 1999, EPA promulgated a final rule on persistent bioaccumulative toxics (PBTs). This rule added several chemicals to the EPCRA Section 313 list of toxic chemicals and established lower reporting thresholds for these and other PBT chemicals that were already reportable. These lower thresholds became applicable in reporting year 2000. In 2001, EPA expanded the PBT rule to include a lower reporting threshold for lead and lead compounds. Facilities that manufacture, process, or otherwise use more than 100 lb of lead or lead compounds must submit a Form R.

  10. 2004 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect

    M. Stockton

    2006-01-15

    Section 313 of Emergency Planning and Community Right-to-Know Act (EPCRA) specifically requires facilities to submit a Toxic Chemical Release Inventory Report (Form R) to the U.S. Environmental Protection Agency (EPA) and state agencies if the owners and operators manufacture, process, or otherwise use any of the listed toxic chemicals above listed threshold quantities. EPA compiles this data in the Toxic Release Inventory database. Form R reports for each chemical over threshold quantities must be submitted on or before July 1 each year and must cover activities that occurred at the facility during the previous year. For reporting year 2004, Los Alamos National Laboratory (LANL or the Laboratory) submitted Form R reports for lead compounds, nitric acid, and nitrate compounds as required under the EPCRA Section 313. No other EPCRA Section 313 chemicals were used in 2004 above the reportable thresholds. This document provides a description of the evaluation of EPCRA Section 313 chemical use and threshold determinations for LANL for calendar year 2004, as well as background information about data included on the Form R reports.

  11. Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding

    PubMed Central

    Chen, Haojun; Wang, Guohao; Lang, Lixin; Jacobson, Orit; Kiesewetter, Dale O.; Liu, Yi; Ma, Ying; Zhang, Xianzhong; Wu, Hua; Zhu, Lei; Niu, Gang; Chen, Xiaoyuan

    2016-01-01

    The efficacy of therapeutic drugs is highly dependent on their optimal in vivo pharmacokinetics. Albumin conjugation is considered to be one of the most effective means of protracting the short lifespan of peptides and proteins. In this study, we proposed a novel platform for developing long lasting therapeutics by conjugating a small molecular albumin binding moiety, truncated Evans blue, to either peptides or proteins. Using the anti-diabetic peptide drug Exendin-4 as a model peptide, we synthesized a new long-acting Exendin-4 derivative (denoted as Abextide). Through complexation with albumin in situ, the biological half-life of Abextide was significantly extended. The hypoglycemic effect of Abextide was also improved remarkably over Exendin-4. Thus, Abextide has considerable potential to treat type 2 diabetes. This strategy as a general technology platform can be applied to other small molecules and biologics for the development of long-acting therapeutic drugs. PMID:26877782

  12. Common synonyms for chemicals listed under section 313 of the Emergency Planning and Community Right-To-Know Act

    SciTech Connect

    Not Available

    1991-01-01

    The glossary contains chemical names and their synonyms for substances covered by the reporting requirements of SARA Title III, section 313. The glossary was developed to aid in determining whether a facility manufactures, processes, or otherwise uses a chemical subject to section 313 reporting. These synonyms are available to the EPA through the public literature, primarily CAS Online. The glossary is divided into two parts. Part 1 is a listing by CAS registry number. Part 2 contains names and synonyms in an alphabetical listing.

  13. Common synonyms: For chemicals listed under Section 313 of the Emergency Planning and Community Right-To-Know act

    SciTech Connect

    Not Available

    1992-06-01

    This glossary contains chemical names and their synonyms for substances covered by the reporting requirements of SARA Title III, section 313. The glossary was developed to aid in determining whether a facility manufactures, processes, or otherwise uses a chemical subject to section 313 reporting. These synonyms are available to the EPA through the public literature, primarily CAS Online. The glossary is divided into two parts. Part 1 is a listing by CAS registry number. Part 2 contains names and synonyms in an alphabetical listing.

  14. 40 CFR 711.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Definitions. 711.3 Section 711.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.3 Definitions. The definitions in this section and the definitions in TSCA section 3 apply to this part....

  15. 40 CFR 711.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Definitions. 711.3 Section 711.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.3 Definitions. The definitions in this section and the definitions in TSCA section 3 apply to this part....

  16. Metal mining facilities. Section 313 of the Emergency Planning and Community Right-to-Know Act, toxic chemical release inventory: Industry guidance

    SciTech Connect

    1999-01-01

    This document is intended to assist establishments and facilities designated by the Standard Industrial Classification (SIC) Major Group 10 (except SIC codes 1011, 1081, and 1094) in making compliance determinations under the EPCRA Section 313 reporting requirements and preparing Form R(s) or the Form A certification statement(s) as required. Chapter 1 serves as an introduction to TRI reporting and provides a brief background on the Emergency Planning and Community Right-to-Know Act and information on where to obtain additional compliance assistance. Chapter 2 begins with how to determine if a facility must report. Chapter 2 concludes with a discussion on how to address trade secrets in reporting and the kinds of records that should be kept to support reporting. Chapter 3 discusses how to calculate the activity thresholds (manufacture, process, and otherwise use) for the EPCRA Section 313 chemicals. Chapter 3 concludes with a discussion of how to determine whether EPCRA Section 313 chemicals exceed a reporting threshold, including focused discussions on issues specific to metal mining facilities. Chapter 4 discusses how to calculate the release and other waste management amounts for those EPCRA Section 313 chemicals for which a report must be prepared. This chapter provides a step-by-step approach designed to minimize the risk of overlooking an activity involving an EPCRA Section 313 chemical and any potential sources or types of releases and other waste management activities that a facility may conduct.

  17. Coal mining facilities: Section 313 of the Emergency Planning and Community Right-to-Know Act. Toxic chemical release inventory

    SciTech Connect

    1999-01-01

    This document is intended to assist establishments and facilities designated by the Standard Industrial Classification (SIC) code 12 (except 1241) in making compliance determinations under the EPCRA Section 313 reporting requirements and preparing Form R(s) or the Form A certification statement(s) as required. The EPCRA Section 313 program is commonly referred to as the Toxic Chemical Release Inventory (TRI) program. This document is organized to provide a step-by-step guide to compliance with EPCRA Section 313, starting with how you determine if your facility must report through completion of the Form R or Form A.

  18. Hanford 1999 Tier 2 Emergency and Hazardous Chemical Inventory Emergency Planning and Community Right to Know Act Section 312

    SciTech Connect

    ZALOUDEK, D.E.

    2000-03-01

    The Hanford Site covers approximately 1,450 square kilometers (560 square miles) of land that is owned by the U.S. Government and managed by the U.S. Department of Energy, Richland Operations Office (DOE-RL). The Hanford Site is located northwest of the city of Richland, Washington. The city of Richland adjoins the southeastern portion of the Hanford Site boundary and is the nearest population center. Activities on the Hanford Site are centralized in numerically designated areas. The 100 Areas, located along the Columbia River, contain deactivated reactors. The processing units are in the 200 Areas, which are on a plateau approximately 11 kilometers (7 miles) from the Columbia River. The 300 Area, located adjacent to and north of Richland, contains research and development laboratories. The 400 Area, 8 kilometers (5 miles) northwest of the 300 Area, contains the Fast Flux Test Facility previously used for testing liquid metal reactor systems. Adjacent to the north of Richland, the 1100 Area contains offices associated with administration, maintenance, transportation, and materials procurement and distribution. The 600 Area covers all locations not specifically given an area designation. This Tier Two Emergency and Hazardous Chemical Inventory report contains information pertaining to hazardous chemicals managed by DOE-RL and its contractors on the Hanford Site. It does not include chemicals maintained in support of activities conducted by others on lands covered by leases, use permits, easements, and other agreements whereby land is used by parties other than DOE-RL. For example, this report does not include chemicals stored on state owned or leased lands (including the burial ground operated by US Ecology, Inc.), lands owned or used by the Bonneville Power Administration (including the Midway Substation and the Ashe Substation), lands used by the National Science Foundation (the Laser Interferometer Gravitational-Wave Observatory), lands leased to the Washington

  19. 1998 Tier two emergency and hazardous chemical inventory - emergency planning and community right-to-know act section 312

    SciTech Connect

    ZALOUDEK, D.E.

    1999-03-02

    The Hanford Site covers approximately 1,450 square kilometers (560 square miles) of land that is owned by the U.S, Government and managed by the U.S. Department of Energy, Richland Operations Office (DOE-RL). The Hanford Site is located northwest of the city of Richland, Washington. The city of Richland adjoins the southeastern portion of the Hanford Site boundary and is the nearest population center. Activities on the Hanford Site are centralized in numerically designated areas. The 100 Areas, located along the Columbia River, contain deactivated reactors. The processing units are in the 200 Areas, which are on a plateau approximately 11 kilometers (7 miles) from the Columbia River. The 300 Area, located adjacent to and north of Richland, contains research and development laboratories. The 400 Area, 8 kilometers (5 miles) northwest of the 300 Area, contains the Fast Flux Test Facility previously used for testing liquid metal reactor systems. Adjacent to the north of Richland, the 1100 Area contains offices associated with administration, maintenance, transportation, and materials procurement and distribution. The 600 Area covers all locations not specifically given an area designation. This Tier Two Emergency and Hazardous Chemical Inventory report contains information pertaining to hazardous chemicals managed by DOE-RL and its contractors on the Hanford Site. It does not include chemicals maintained in support of activities conducted by others on lands covered by leases, use permits, easements, and other agreements whereby land is used by parties other than DOE-RL. For example, this report does not include chemicals stored on state owned or leased lands (including the burial ground operated by US Ecology, Inc.), lands owned or used by the Bonneville Power Administration (including the Midway Substation and the Ashe Substation), lands used by the National Science Foundation (the Laser Interferometer Gravitational-Wave Observatory), lands leased to the Washington

  20. Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

    PubMed Central

    Ilyushin, Denis G.; Smirnov, Ivan V.; Belogurov, Alexey A.; Dyachenko, Igor A.; Zharmukhamedova, Tatiana Iu.; Novozhilova, Tatjana I.; Bychikhin, Eugene A.; Serebryakova, Marina V.; Kharybin, Oleg N.; Murashev, Arkadii N.; Anikienko, Konstantin A.; Nikolaev, Eugene N.; Ponomarenko, Natalia A.; Genkin, Dmitry D.; Blackburn, G. Michael; Masson, Patrick; Gabibov, Alexander G.

    2013-01-01

    The creation of effective bioscavengers as a pretreatment for exposure to nerve agents is a challenging medical objective. We report a recombinant method using chemical polysialylation to generate bioscavengers stable in the bloodstream. Development of a CHO-based expression system using genes encoding human butyrylcholinesterase and a proline-rich peptide under elongation factor promoter control resulted in self-assembling, active enzyme multimers. Polysialylation gives bioscavengers with enhanced pharmacokinetics which protect mice against 4.2 LD50 of S-(2-(diethylamino)ethyl) O-isobutyl methanephosphonothioate without perturbation of long-term behavior. PMID:23297221

  1. Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-Acting C-Methyltransferase and Source of Chemical Diversity Generation**

    PubMed Central

    Tsunematsu, Yuta; Fukutomi, Manami; Saruwatari, Takayoshi; Noguchi, Hiroshi; Watanabe, Kenji; Hotta, Kinya; Tang, Yi

    2015-01-01

    Pseurotins comprise a family of structurally related Aspergillal natural products having interesting bioactivity. However, little is known about the biosynthetic steps involved in the formation of their complex chemical features. Here, we systematically deleted the pseurotin biosynthetic genes in A. fumigatus and performed in vivo and in vitro characterization of the tailoring enzymes to determine the biosynthetic intermediates and the gene products responsible for the formation of each intermediate. This allowed us to elucidate the main biosynthetic steps leading to the formation of pseurotin A from the predominant precursor, azaspirene. The study revealed the combinatorial nature of the biosynthesis of the pseurotin family of compounds and the intermediates. Most interestingly, we report the first identification of an epoxidase–C-methyltransferase bifunctional fusion protein PsoF that appears to methylate the nascent polyketide backbone carbon atom in trans. PMID:24939566

  2. Roadmaps to sources of information on chemicals listed in the Emergency Planning Community and Community Right-To-Know Act (also known as SARA Title 3), Section 313. Toxic release inventory (for microcomputers). Data file

    SciTech Connect

    Not Available

    1991-09-01

    EPA has developed a database of sources of information on the chemicals listed in section 313 of the Superfund Amendments and Reauthorization Act (SARA). The datbase is intended to assist users of section 313 Toxic Release Inventory data to perform exposure and risk assessments of these chemicals. The Roadmaps system displays and/or prints information for the SARA section 313 chemicals on health and environmental effects, Federal regulations, and state air and water regulations, monitoring data, and state contacts.

  3. Electricity generating facilities. Section 313 of the Emergency Planning and Community Right-to-Know Act, toxic chemical release inventory: Industry guidance

    SciTech Connect

    1999-01-01

    This document is intended to assist establishments and facilities designated by the Standard Industrial Classification (SIC) codes 4911 (limited to facilities that combust coal and/or oil for the purpose of generating electricity for distribution in commerce), 4931 (limited to facilities that combust coal and/or oil for the purpose of generating electricity for distribution in commerce), and 4939 (limited to facilities that combust coal and/or oil for the purpose of generating electricity for distribution in commerce) in making compliance determinations under the EPCRA Section 313 reporting requirements and preparing Form R(s) or the Form A certification statement(s) as required. Chapter 1 serves as an introduction to TRI reporting and provides a brief background on the Emergency Planning and Community Right-to-Know Act and information on where to obtain additional compliance assistance. Chapter 2 begins with how to determine if a facility must report. Chapter 2 concludes with a discussion on how to address trade secrets in reporting and the kinds of records that should be kept to support reporting. Chapter 3 discusses how to calculate the activity thresholds (manufacture, process, and otherwise use) for the EPCRA Section 313 chemicals. Chapter 3 concludes with a discussion of how to determine whether EPCRA Section 313 chemicals exceed a reporting threshold, including focused discussions on issues specific to electricity generating facilities. Chapter 4 discusses how to calculate the release and other waste management amounts for those EPCRA Section 313 chemicals for which a report must be prepared. This chapter provides a step-by-step approach designed to minimize the risk of overlooking an activity involving an EPCRA Section 313 chemical and any potential sources or types of releases and other waste management activities that a facility may conduct.

  4. 77 FR 34777 - Seventieth Report of the TSCA Interagency Testing Committee to the Administrator of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... dermal absorption rate data, and 164 High Production Volume (HPV) Challenge Program orphan chemicals; a...-(1,1,3,3- Recommended. tetramethylbutyl)-. 55 December 2004...... 161 High Production Volume (HPV) Recommended. Challenge Program orphan chemicals. 56 August 2005........ 3 HPV Challenge Program...

  5. 40 CFR 799.9530 - TSCA in vitro mammalian cell gene mutation test.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... chemical substances. Suitable cell lines include L5178Y mouse lymphoma cells, the CHO, AS52 and V79 lines.... Differential Mutant Quantitation at the Mouse Lymphoma TK and CHO HGPRT Loci. Mutagenesis. 4, 394-403 (1989...., Batson, A.G., and Clive, D. Eds. Kilbey, B.J. et al. Procedures for the L5178Y/TK=/− > TK=/−...

  6. Progress report and technology status development of an EG and G Berthold LB-150 alpha/beta particulate monitor for use on the East Tennessee Technology Park Toxic Substances Control Act Incinerator

    SciTech Connect

    Shor, J.T.; Singh, S.P.N.; Gibson, L.V. Jr.

    1998-06-01

    The purpose of this project was to modify and evaluate a commercially available EG and G Berthold LB-150 alpha-beta radionuclide particulate monitor for the high-temperature and moisture-saturation conditions of the East Tennessee Technology Park (formerly K-25 Site) Toxic Substances Control Act (TSCA) Incinerator stack. The monitor was originally outfitted for operation at gas temperatures of 150 F on the defunct Los Alamos National Laboratory (LANL) controlled air incinerator, and the objective was to widen its operating envelope. A laboratory apparatus was constructed that simulated the effects of water-saturated air at the TSCA Incinerator stack-gas temperatures, 183 F. An instrumented set of heat exchangers was constructed to then condition the gas so that the radionuclide monitor could be operated without condensation. Data were collected under the conditions of the elevated temperatures and humidities and are reported herein, and design considerations of the apparatus are provided. The heat exchangers and humidification equipment performed as designed, the Mylar film held, and the instrument suffered no ill effects. However, for reasons as yet undetermined, the sensitivity of the radionuclide detection diminishes as the gas temperature is elevated, whether the gas is humidified or not. The manufacturer has had no experience with (a) the operation of the monitor under these conditions and (b) any commercial market that might exist for an instrument that operates under these conditions. The monitor was not installed into the radiologically contaminated environment of the TSCA Incinerator stack pending resolution of this technical issue.

  7. Toxic substances Control Act inspection manual. Vol. 1 and Vol. 2. Part 1

    SciTech Connect

    Not Available

    1982-01-01

    Volume one: Toxic Substances Control Act base manual provides general information relating to the act. Inspector authorities and responsibilities are discussed along with the elements and scope of inspections. Procedures which are common to all inspections are outlined in detail: Pre-Inspection Preparation, Entry, Opening Conference, Records Inspection, Documentary Support, Sampling, Chain of Custody, Safety, Closing Conference, and Report Preparation. Special procedures are listed, and all TSCA forms are presented and explained. Information is also included on data systems, warrants, shipping samples, and testifying in court. Volume two: provides the specific information necessary for conducting a comprehensive inspection for PCBs. An Enforcement Strategy details EPA plans and provides an overview of the regulation. Inspecting, sampling, and reporting procedures for PCBs in specific industries are provided.

  8. Emergency Planning and Community Right-to-Know Act, section 313 toxic chemical release inventory reporting forms for calendar year 1996

    SciTech Connect

    Evans, R.A.

    1997-06-01

    This document contains the Toxic Chemical Release Inventory Reporting Forms and the Toxic Chemical Release Inventory Certification Statement Form A(s) for chlorine for 1996 for the Y-12 Plant in Oak Ridge, Tennessee. The reporting forms contain information on the Lockheed Martin Energy Systems Y-12 Plant and Johnson Controls Water Treatment Plant operational releases for specific toxic chemicals to the air, water, and land in addition to transfers to off-site disposal locations in CY 1996. Personnel from U.S. West reported no usage of the specified toxic chemicals in CY 1996; therefore, no Form R or Form A reporting data are included for U.S. West.

  9. 75 FR 80665 - Sixty-Seventh Report of the TSCA Interagency Testing Committee to the Administrator of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... chemicals with insufficient dermal absorption rate data, and 207 High Production Volume (HPV) Challenge... (HPV) Recommended. Challenge Program orphan chemicals. 56 August 2005 4 HPV Challenge Program...

  10. Toxic chemical release inventory magnetic media submission instructions. Section 313 of the Emergency Planning and Community Right-To-Know Act (revised 1990 version)

    SciTech Connect

    Not Available

    1991-01-01

    The document provides basic specifications for the use of magnetic media to submit EPA Form R reports required by section 313 of the Emergency Planning and Community Right-to-Know Act (Title III of the Superfund Amendments and Reauthorization Act of 1986), Public Law 99-499. The use of magnetic media can be a convenient and timesaving way to submit required information. The specifications and requirements presented in the document supplement the reporting requirements presented in the section 313 final rule (40 CFR Part 372). Submission of magnetic media reports does not relieve the submitter from any of the regulatory requirements of the section 313 final rule.

  11. Toxic chemical release inventory magnetic media submission instructions. Section 313 of the emergency planning and community right-to-know act (revision)

    SciTech Connect

    Not Available

    1989-01-01

    This document provides basic specifications for the use of magnetic media to submit EPA Form R reports required by Section 313 of the Emergency Planning and Community Right-to-Know Act (Title III of the Superfund Amendments and Reauthorization Act of 1986), Public Law 99-499. The specifications and requirements presented in the document supplement to the reporting requirements presented in the Section 313 final rule (40 CFR Part 372). Submission of magnetic-media reports does not relieve the submitter from any of the regulatory requirements of the Section 313 final rule.

  12. First-in-humans study of the safety, tolerability, and pharmacokinetics of ACT-451840, a new chemical entity with antimalarial activity.

    PubMed

    Bruderer, Shirin; Hurst, Noémie; de Kanter, Ruben; Miraval, Tommaso; Pfeifer, Thomas; Donazzolo, Yves; Dingemanse, Jasper

    2015-02-01

    Emerging resistance to antimalarial agents raises the need for new drugs. ACT-451840 is a new compound with potent activity against sensitive and resistant Plasmodium falciparum strains. This was a first-in-humans single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of ACT-451840 across doses of 10, 50, 200, and 500 mg in healthy male subjects. In the 200- and 500-mg dose groups, the effect of food was investigated, and antimalarial activity was assessed using an ex vivo bioassay with P. falciparum. No (serious) adverse events leading to discontinuation were reported. At the highest dose level, the peak drug concentration (Cmax) and the area under the plasma concentration-time curve from zero to infinity of ACT-451840 under fasted conditions reached 11.9 ng/ml and 100.6 ng·h/ml, respectively, and these were approximately 13-fold higher under fed conditions. Food did not affect the half-life (approximately 34 h) of the drug, while the Cmax was attained 2.0 and 3.5 h postdose under fasted and fed conditions, respectively. The plasma concentrations estimated by the bioassay were approximately 4-fold higher than those measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Several potentially active metabolites were also identified. ACT-451840 was well tolerated across all doses. Exposure to ACT-451840 significantly increased with food. The bioassay indicated the presence of circulating active metabolites. (This study has been registered at ClinicalTrials.gov under registration no. NCT02186002.). PMID:25421475

  13. First-in-Humans Study of the Safety, Tolerability, and Pharmacokinetics of ACT-451840, a New Chemical Entity with Antimalarial Activity

    PubMed Central

    Bruderer, Shirin; Hurst, Noémie; de Kanter, Ruben; Miraval, Tommaso; Pfeifer, Thomas; Donazzolo, Yves

    2014-01-01

    Emerging resistance to antimalarial agents raises the need for new drugs. ACT-451840 is a new compound with potent activity against sensitive and resistant Plasmodium falciparum strains. This was a first-in-humans single-ascending-dose study to investigate the safety, tolerability, and pharmacokinetics of ACT-451840 across doses of 10, 50, 200, and 500 mg in healthy male subjects. In the 200- and 500-mg dose groups, the effect of food was investigated, and antimalarial activity was assessed using an ex vivo bioassay with P. falciparum. No (serious) adverse events leading to discontinuation were reported. At the highest dose level, the peak drug concentration (Cmax) and the area under the plasma concentration-time curve from zero to infinity of ACT-451840 under fasted conditions reached 11.9 ng/ml and 100.6 ng · h/ml, respectively, and these were approximately 13-fold higher under fed conditions. Food did not affect the half-life (approximately 34 h) of the drug, while the Cmax was attained 2.0 and 3.5 h postdose under fasted and fed conditions, respectively. The plasma concentrations estimated by the bioassay were approximately 4-fold higher than those measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Several potentially active metabolites were also identified. ACT-451840 was well tolerated across all doses. Exposure to ACT-451840 significantly increased with food. The bioassay indicated the presence of circulating active metabolites. (This study has been registered at ClinicalTrials.gov under registration no. NCT02186002.) PMID:25421475

  14. Chemical Leukoderma.

    PubMed

    Bonamonte, Domenico; Vestita, Michelangelo; Romita, Paolo; Filoni, Angela; Foti, Caterina; Angelini, Gianni

    2016-01-01

    Chemical leukoderma, often clinically mimicking idiopathic vitiligo and other congenital and acquired hypopigmentation, is an acquired form of cutaneous pigment loss caused by exposure to a variety of chemicals that act through selective melanocytotoxicity. Most of these chemicals are phenols and aromatic or aliphatic catechols derivatives. These chemicals, however, are harmful for melanocytes in individuals with an individual susceptibility. Nowadays, chemical leukoderma is fairly common, caused by common domestic products. The presence of numerous acquired confetti- or pea-sized macules is clinically characteristic of chemical leukoderma, albeit not diagnostic. Other relevant diagnostic elements are a history of repeated exposure to a known or suspected depigmenting agent at the sites of onset and a macules distribution corresponding to sites of chemical exposure. Spontaneous repigmentation has been reported when the causative agent is avoided; the repigmentation process is perifollicular and gradual, taking place for a variable period of weeks to months. PMID:27172302

  15. Uranium effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator

    SciTech Connect

    Shor, J.T.; Bostick, W.D.; Hoffmann, D.P.; Gibson, L.V. Jr.; Ho, T.C.

    1993-07-01

    The Oak Ridge K-25 Site Toxic Substances Control Act (TSCA) Incinerator has been undergoing a series of routine tests to determine uranium partitioning to the stack, scrubber waters, and bottom ash. This paper discusses the results of the most recent experiment in which relatively high rates of uranium stack gas emissions were identified: 6.11 g/h or 8 wt % based on the uranium feed. These data are compared with earlier data, and an empirical correlation is suggested between the stack emissions of uranium and the product of the uranium and chlorine concentration of the feed. This is consistent with certain findings with other metals, in which increasing chlorine feed contents led to increasing emissions.

  16. RCRA Subtitle C TSD facilities and solvent recovery facilities: Section 313 of the Emergency Planning and Community Right-to-Know Act. Toxic chemical release inventory; Industry guidance

    SciTech Connect

    1999-01-01

    The purpose of this guidance document is to assist facilities in SIC code 4953 that are regulated under the Resource Conservation and Recovery Act (RCRA), Subtitle C and facilities in SIC code 7389 that are primarily engaged in solvent recovery services on a contract or fee basis. This document explains the EPCRA Section 313 and PPA Section 6607 reporting requirements (collectively referred to as the EPCRA Section 313) reporting requirements, and discusses specific release and other waste management activities encountered at many facilities in these industries. The objectives of this manual are to: clarify EPCRA Section 313 requirements for industry; increase the accuracy and completeness of the data being reported by RCRA Subtitle C TSD and solvent recovery facilities; and reduce the level of effort expended by those facilities that prepare an EPCRA Section 313 report.

  17. 75 FR 5405 - Sixty-Fifth Report of the TSCA Interagency Testing Committee to the Administrator of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... Register issue of January 28, 2008 (73 FR 4861) (FRL-8344-5) available on-line at http://www.epa.gov... alkylphenols, 12 lead compounds, 16 chemicals with insufficient dermal absorption rate data, and 207 HPV... Volume (HPV) Challenge Program orphan chemicals 56 August 2005 4 HPV Challenge Program Recommended...

  18. 40 CFR 710.32 - Reporting information to EPA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... address set forth in § 710.39. (3) The specific chemical name and Chemical Abstracts Service (CAS... CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS 2002 Inventory Update Reporting § 710.32 Reporting... section for each chemical substance described in § 710.25 that the person manufactured for...

  19. Balancing Acts

    MedlinePlus

    ... Current Issue Past Issues Special Section: Focus on Communication Balancing Acts Past Issues / Fall 2008 Table of ... from the National Institute on Deafness and Other Communication Disorders (NIDCD). It involves simulated trips down the ...

  20. Acting Atoms.

    ERIC Educational Resources Information Center

    Farin, Susan Archie

    1997-01-01

    Describes a fun game in which students act as electrons, protons, and neutrons. This activity is designed to help students develop a concrete understanding of the abstract concept of atomic structure. (DKM)

  1. ACT Test

    MedlinePlus

    ... this page helpful? Also known as: ACT; Activated Coagulation Time Formal name: Activated Clotting Time Related tests: ... in the blood called platelets and proteins called coagulation factors are activated in a sequence of steps ...

  2. Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? The Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors.

    PubMed

    Iranshahi, Mehrdad; Chini, Maria Giovanna; Masullo, Milena; Sahebkar, Amirhossein; Javidnia, Azita; Chitsazian Yazdi, Mahsa; Pergola, Carlo; Koeberle, Andreas; Werz, Oliver; Pizza, Cosimo; Terracciano, Stefania; Piacente, Sonia; Bifulco, Giuseppe

    2015-12-24

    Curcumin, or diferuloylmethane, a polyphenolic molecule isolated from the rhizome of Curcuma longa, is reported to modulate multiple molecular targets involved in cancer and inflammatory processes. On the basis of its pan-inhibitory characteristics, here we show that simple chemical modifications of the curcumin scaffold can regulate its biological selectivity. In particular, the curcumin scaffold was modified with three types of substituents at positions C-1, C-8, and/or C-8' [C5 (isopentenyl, 5-8), C10 (geranyl, 9-12), and C15 (farnesyl, 13, 14)] in order to make these molecules more selective than the parent compound toward two specific targets: histone deacetylase (HDAC) and microsomal prostaglandin E2 synthase-1 (mPGES-1). From combined in silico and in vitro analyses, three selective inhibitors by proper substitution at position 8 were revealed. Compound 13 has improved HDAC inhibitory activity and selectivity with respect to the parent compound, while 5 and 9 block the mPGES-1 enzyme. We hypothesize about the covalent interaction of curcumin, 5, and 9 with the mPGES-1 binding site. PMID:26588603

  3. Field Evaluation of MERCEM Mercury Emission Analyzer System at the Oak Ridge TSCA Incinerator East Tennessee Technology Park Oak Ridge, Tennessee

    SciTech Connect

    2000-03-01

    The authors reached the following conclusions: (1) The two-month evaluation of the MERCEM total mercury monitor from Perkin Elmer provided a useful venue in determining the feasibility of using a CEM to measure total mercury in a saturated flue gas. (2) The MERCEM exhibited potential at a mixed waste incinerator to meet requirements proposed in PS12 under conditions of operation with liquid feeds only at stack mercury concentrations in the range of proposed MACT standards. (3) Performance of the MERCEM under conditions of incinerating solid and liquid wastes simultaneously was less reliable than while feeding liquid feeds only for the operating conditions and configuration of the host facility. (4) The permeation tube calibration method used in this test relied on the CEM internal volumetric and time constants to relate back to a concentration, whereas a compressed gas cylinder concentration is totally independent of the analyzer mass flowmeter and flowrates. (5) Mercury concentration in the compressed gas cylinders was fairly stable over a 5-month period. (6) The reliability of available reference materials was not fully demonstrated without further evaluation of their incorporation into routine operating procedures performed by facility personnel. (7) The degree of mercury control occurring in the TSCA Incinerator off-gas cleaning system could not be quantified from the data collected in this study. (8) It was possible to conduct the demonstration at a facility incinerating radioactively contaminated wastes and to release the equipment for later unrestricted use elsewhere. (9) Experience gained by this testing answered additional site-specific and general questions regarding the operation and maintenance of CEMs and their use in compliance monitoring of total mercury emissions from hazardous waste incinerators.

  4. Chemical Facility Security Improvement Act of 2013

    THOMAS, 113th Congress

    Rep. Jackson Lee, Sheila [D-TX-18

    2013-01-03

    02/12/2013 Referred to the Subcommittee on Cybersecurity, Infrastructure Protection, and Security Technologies. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. Representation of chemical information in OASIS centralized 3D database for existing chemicals.

    PubMed

    Nikolov, Nikolai; Grancharov, Vanio; Stoyanova, Galya; Pavlov, Todor; Mekenyan, Ovanes

    2006-01-01

    The present inventory of existing chemicals in regulatory agencies in North America and Europe, encompassing the chemicals of the European Chemicals Bureau (EINECS, with 61 573 discrete chemicals); the Danish EPA (159 448 chemicals); the U.S. EPA (TSCA, 56 882 chemicals; HPVC, 10 546 chemicals) and pesticides' active and inactive ingredients of the U.S. EPA (1379 chemicals); the Organization for Economic Cooperation and Development (HPVC, 4750 chemicals); Environment Canada (DSL, 10851 chemicals); and the Japanese Ministry of Economy, Trade, and Industry (16811), was combined in a centralized 3D database for existing chemicals. The total number of unique chemicals from all of these databases exceeded 185 500. Defined and undefined chemical mixtures and polymers are handled, along with discrete (hydrolyzing and nonhydrolyzing) chemicals. The database manager provides the storage and retrieval of chemical structures with 2D and 3D data, accounting for molecular flexibility by using representative sets of conformers for each chemical. The electronic and geometric structures of all conformers are quantum-chemically optimized and evaluated. Hence, the database contains over 3.7 million 3D records with hundreds of millions of descriptor data items at the levels of structures, conformers, or atoms. The platform contains a highly developed search subsystem--a search is possible on Chemical Abstracts Service numbers; names; 2D and 3D fragment searches; structural, conformational, or atomic properties; affiliation in other chemical databases; structure similarity; logical combinations; saved queries; and search result exports. Models (collections of logically related descriptors) are supported, including information on a model's author, date, bioassay, organs/tissues, conditions, administration, and so forth. Fragments can be interactively constructed using a visual structure editor. A configurable database browser is designed for the inspection and editing of all types of

  6. 76 FR 69238 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ...; ] CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD Sunshine Act Meeting In connection with its investigation into three iron dust flash fires at the Hoeganaes facility in Gallatin, TN., the U.S. Chemical Safety... prior to the public meeting. For more information, please contact the Chemical Safety and...

  7. 77 FR 20354 - Meetings; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... From the Federal Register Online via the Government Publishing Office CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD Meetings; Sunshine Act The U.S. Chemical Safety and Hazard Investigation Board (CSB... Nemours and Co. Inc. chemical plant in Buffalo, New York. The incident involved a contract welder...

  8. PEER REVIEW OF THE PERSISTENT, BIOACCUMULATIVE, AND TOXIC (PBT) PROFILER

    EPA Science Inventory

    The U.S. EPA is required, under Sections 4, 5, and 6 of the Toxic Substances Control Act (TSCA), to screen chemicals for potential risk to humans and the environment. OPPT has developed computerized methods designed to support screening-level assessment of chemicals in the absen...

  9. 77 FR 19861 - Certain Polybrominated Diphenylethers; Significant New Use Rule and Test Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ...The Agency is proposing to amend the Toxic Substances Control Act (TSCA) section 5(a) Significant New Use Rule (SNUR), for certain polybrominated diphenylethers (PBDEs) by: Designating processing of six PBDEs, or any combination of these chemical substances resulting from a chemical reaction, as a significant new use; designating manufacturing, importing, and processing of a seventh PBDE,......

  10. 40 CFR 710.4 - Scope of the inventory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Scope of the inventory. 710.4 Section 710.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT COMPILATION OF THE TSCA CHEMICAL SUBSTANCE INVENTORY § 710.4 Scope of the inventory. (a) Chemical substances subject to these regulations....

  11. 77 FR 17386 - Significant New Use Rule for Hexabromocyclododecane and 1,2,5,6,9,10-Hexabromocyclododecane

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ...EPA is proposing a significant new use rule (SNUR) under section 5(a)(2) of the Toxic Substances Control Act (TSCA) for two chemical substances: Hexabromocyclododecane (Chemical Abstracts Service Registry Number (CASRN) 25637-99-4) and 1,2,5,6,9,10- hexabromocyclododecane (CASRN 3194-55-6), hereinafter collectively referred to as HBCD. This proposed rule would designate ``use in consumer......

  12. Act resilient.

    PubMed

    Joseph, Genie; Bice-Stephens, Wynona

    2014-01-01

    Attendees have reported changing from being fearful to serene, from listless to energized, from disengaged to connected, and becoming markedly less anxious in a few weeks. Anecdotally, self-reported stress levels have been reduced by over 50% after just one class. Attendees learn not to be afraid of their feelings by working with emotions in a playful manner. When a person can act angry, but separate himself from his personal story, the emotional energy exists in a separate form that is not attached to specific events, and can be more easily dealt with and neutralized. Attendees are taught to "take out the emotional trash" through expressive comedy. They become less intimated by their own emotional intensity and triggers as they learn how even metaphorical buckets of anger, shame, guilt and hurt can be emotionally emptied. The added benefit is that this is accomplished without the disclosure of personal information of the requirement to reexperience past pain which can trigger its own cascade of stress. PMID:24706248

  13. Microorganisms and Chemical Pollution

    ERIC Educational Resources Information Center

    Alexander, M.

    1973-01-01

    Discusses the importance of microorganisms in chemical pollution and pollution abatement. Selected chemical pollutants are chosen to illustrate that microorganisms synthesize hazardous substances from reasonably innocuous precursors, while others act as excellent environmental decontaminating agents by removing undesirable natural and synthetic…

  14. TOXIC SUBSTANCES CONTROL ACT TEST SUBMISSIONS (TSCATS)

    EPA Science Inventory

    Toxic Substances Control Act Test Submissions (TSCATS) is an online index to unpublished, nonconfidential studies covering chemical testing results and adverse effects of chemicals on health and ecological systems. The studies are submitted by U.S. industry to EPA under several s...

  15. 40 CFR 711.35 - Electronic filing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Electronic filing. 711.35 Section 711.35 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.35 Electronic filing. (a) You must use e-CDRweb...

  16. 40 CFR 711.35 - Electronic filing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Electronic filing. 711.35 Section 711.35 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.35 Electronic filing. (a) You must use e-CDRweb...

  17. 40 CFR 710.38 - Confidentiality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS 2002 Inventory Update Reporting § 710.38 Confidentiality. (a) Any person... if the identity of that substance is treated as confidential in the Master Inventory File as of...

  18. 40 CFR 710.58 - Confidentiality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS Inventory Update Reporting for 2006 and Beyond § 710.58 Confidentiality. (a... Inventory File as of the time the report is submitted for that substance under this subpart. The...

  19. 76 FR 77224 - Access to Confidential Business Information by Primus Solutions, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Toxic Substances Control Act (TSCA). Some of the information may be claimed or determined to be... interest to all who manufacture, process, or distribute industrial chemicals. Since other entities may also... information is not publicly available, e.g., CBI or other information whose disclosure is restricted...

  20. 77 FR 29635 - Access to Confidential Business Information by Several Student Services Contractors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... Control Act (TSCA). Some of the information may be claimed or determined to be Confidential Business... interest to all who manufacture, process, or distribute industrial chemicals. Since other entities may also... information is not publicly available, e.g., CBI or other information whose disclosure is restricted...

  1. 78 FR 67139 - Access to Confidential Business Information by Eastern Research Group and Its Identified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... sections of the Toxic Substances Control Act (TSCA). Some of the information may be claimed or determined... interest to all who manufacture, process, or distribute industrial chemicals. Since other entities may also... information is not publicly available, e.g., CBI or other information whose disclosure is restricted...

  2. 75 FR 24688 - Access to Confidential Business Information by Guident Technologies Inc.’s Identified Subcontractor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... has been submitted to EPA under all sections of the Toxic Substances Control Act (TSCA). Some of the... manufacture, process or distribute industrial chemicals. Since other entities may also be interested, the... available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other...

  3. 40 CFR 711.15 - Reporting information to EPA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Reporting information to EPA. 711.15 Section 711.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.15 Reporting information to EPA. For the 2012 submission period, any person who...

  4. 40 CFR 710.50 - Activities for which reporting is not required.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Activities for which reporting is not... SUBSTANCES CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS Inventory Update Reporting for 2006 and Beyond § 710.50 Activities for which reporting is not required. A person described in § 710.48 is not...

  5. 40 CFR 710.30 - Activities for which reporting is not required.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Activities for which reporting is not... SUBSTANCES CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS 2002 Inventory Update Reporting § 710.30 Activities for which reporting is not required. A person described in § 710.28 is not subject to...

  6. 40 CFR 710.52 - Reporting information to EPA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Reporting information to EPA. 710.52 Section 710.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT TSCA CHEMICAL INVENTORY REGULATIONS Inventory Update Reporting for 2006 and Beyond § 710.52 Reporting information to EPA. Any person...

  7. Effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator emissions tests of January 16 and 18, 1991

    SciTech Connect

    Shor, J.T. ); Bostick, W.D.; Coroneos, A.C.; Bunch, D.H.; Gibson, L.V.; Hoffmann, D.P.; Shoemaker, J.L. )

    1992-02-01

    On January 16 and 18, 1991, special emissions tests were conducted at the Oak Ridge, K-25 Site Toxic Substances Control Act (TSCA) Incinerator. Both tests were approximately 6 h long and were performed at TSCA temperatures (1200{degrees}C, secondary combustion chamber (SSC)). Liquid feed and effluent samples were collected every 30 min. A filter was used to collect particles from stack gases to study morphology and composition during the first test. Isokinetic air samples were also taken during the second test. Metals emissions from the second test were evaluated using the Environmental Protection Agency (EPA) Method 5 sampling train. The aqueous waste was collected and fed in batches to the Central Neutralization Facility (CNF), where it was treated by iron coprecipitation and polymer flocculation and data were collected. In the first test (1-16-91), the aqueous and organic wastes were fed directly to the kiln or primary combustion chamber (PCC). In the second test (1-18-91), the remaining organic waste from the first test was fed into the SSC, and other organic waste was fed into the PCC. One objective of the two tests was to determine if feeding the same organic waste into the two combustion chambers made a difference in a partitioning of uranium and other metals. No evaluation of radionuclides other than uranium was made. The partition coefficient of uranium to the quench water was 0.3 on January 16 and 0.35 on January 18; so directing Tank 306A to the feed to the primary vs the secondary combustion chamber appears to have made little difference. The partition coefficient of uranium to the stack on January 18 was 0.0039. 5 refs., 15 figs., 26 tabs.

  8. Effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator emissions tests of January 16 and 18, 1991

    SciTech Connect

    Shor, J.T.; Bostick, W.D.; Coroneos, A.C.; Bunch, D.H.; Gibson, L.V.; Hoffmann, D.P.; Shoemaker, J.L.

    1992-02-01

    On January 16 and 18, 1991, special emissions tests were conducted at the Oak Ridge, K-25 Site Toxic Substances Control Act (TSCA) Incinerator. Both tests were approximately 6 h long and were performed at TSCA temperatures [1200{degrees}C, secondary combustion chamber (SSC)]. Liquid feed and effluent samples were collected every 30 min. A filter was used to collect particles from stack gases to study morphology and composition during the first test. Isokinetic air samples were also taken during the second test. Metals emissions from the second test were evaluated using the Environmental Protection Agency (EPA) Method 5 sampling train. The aqueous waste was collected and fed in batches to the Central Neutralization Facility (CNF), where it was treated by iron coprecipitation and polymer flocculation and data were collected. In the first test (1-16-91), the aqueous and organic wastes were fed directly to the kiln or primary combustion chamber (PCC). In the second test (1-18-91), the remaining organic waste from the first test was fed into the SSC, and other organic waste was fed into the PCC. One objective of the two tests was to determine if feeding the same organic waste into the two combustion chambers made a difference in a partitioning of uranium and other metals. No evaluation of radionuclides other than uranium was made. The partition coefficient of uranium to the quench water was 0.3 on January 16 and 0.35 on January 18; so directing Tank 306A to the feed to the primary vs the secondary combustion chamber appears to have made little difference. The partition coefficient of uranium to the stack on January 18 was 0.0039. 5 refs., 15 figs., 26 tabs.

  9. The new Clean Air Act

    SciTech Connect

    Padmanabha, A.P. ); Olem, H. )

    1991-05-01

    This article is a title by title review of the new Clean Air Act and how it affects water quality and wastewater treatment. The bill provides for restoring and protecting lakes and rivers by reducing acid-rain-causing emissions and toxics from nonpoint-source runoff. Topics covered include urban smog, mobile sources, air toxics, acid rain, permits, ozone-depleting chemicals, enforcement, and the law's socio-economic impacts.

  10. SAMPLING FOR ORGANIC CHEMICALS IN AIR

    EPA Science Inventory

    Organic chemicals by far account for the majority of pollutants found in air. ore than 90% of the 75,000 chemicals listed in EPA's Toxic Substances Control Act Chemical Substance Inventory and 88% of the 189 Hazardous Air Pollutants (HAPS) named in the Clean Air Act Amendments of...

  11. BINDING OF CHEMICAL CARCINOGENS AND MUTAGENS TO RAT HEMOGLOBIN

    EPA Science Inventory

    The alkylation of hemoglobin is a proposed dose monitor for chemical carcinogens and mutagens. The binding of fifteen chemical carcinogens and mutagens to rat hemoglobin was determined. Direct acting carcinogens and indirect acting carcinogens including aromatic amines, halogenat...

  12. Compliance under the Community Right-to-Know Act

    SciTech Connect

    Bradford, J.R.; Vaughn, R.C.; Breazeale, A.

    1995-12-31

    In 1986, the Superfund Amendments and Reauthorization Act (SARA) provided additional funding to continue and greatly expand the cleanup program begun under CERCLA. Title III of SARA contains the provisions of the Emergency Planning and Community Right-to-Know Act (EPCRA). SARA Title III may prove to be more pervasive and more demanding for industry than any of the other many rules and regulations promulgated by the Environmental Protection Agency. The Emergency Planning and Community Right-to-Know Act has four major provisions: planning for chemical emergencies; emergency notification of chemical accidents and releases; reporting of hazardous chemical inventories; and toxic chemical release reporting.

  13. Chemical Emergencies

    MedlinePlus

    When a hazardous chemical has been released, it may harm people's health. Chemical releases can be unintentional, as in the case of an ... the case of a terrorist attack with a chemical weapon. Some hazardous chemicals have been developed by ...

  14. ACTS data center

    NASA Technical Reports Server (NTRS)

    Syed, Ali; Vogel, Wolfhard J.

    1993-01-01

    Viewgraphs on ACTS Data Center status report are included. Topics covered include: ACTS Data Center Functions; data flow overview; PPD flow; RAW data flow; data compression; PPD distribution; RAW Data Archival; PPD Audit; and data analysis.

  15. ACTS data center

    NASA Astrophysics Data System (ADS)

    Syed, Ali; Vogel, Wolfhard J.

    1993-08-01

    Viewgraphs on ACTS Data Center status report are included. Topics covered include: ACTS Data Center Functions; data flow overview; PPD flow; RAW data flow; data compression; PPD distribution; RAW Data Archival; PPD Audit; and data analysis.

  16. Recovery Act Milestones

    SciTech Connect

    Rogers, Matt

    2009-01-01

    Every 100 days, the Department of Energy is held accountable for a progress report on the American Recovery and Reinvestment Act. Update at 200 days, hosted by Matt Rogers, Senior Advisor to Secretary Steven Chu for Recovery Act Implementation.

  17. Recovery Act Milestones

    ScienceCinema

    Rogers, Matt

    2013-05-29

    Every 100 days, the Department of Energy is held accountable for a progress report on the American Recovery and Reinvestment Act. Update at 200 days, hosted by Matt Rogers, Senior Advisor to Secretary Steven Chu for Recovery Act Implementation.

  18. Forgetting ACT UP

    ERIC Educational Resources Information Center

    Juhasz, Alexandra

    2012-01-01

    When ACT UP is remembered as the pinnacle of postmodern activism, other forms and forums of activism that were taking place during that time--practices that were linked, related, just modern, in dialogue or even opposition to ACT UP's "confrontational activism"--are forgotten. In its time, ACT UP was embedded in New York City, and a larger world,…

  19. Act II of the Sunshine Act.

    PubMed

    Pham-Kanter, Genevieve

    2014-11-01

    To coincide with the introduction in the United States of the Sunshine Act, Genevieve Pham-Kanter discusses what we need to look for to fight hidden bias and deliberate or unconscious corruption. Please see later in the article for the Editors' Summary. PMID:25369363

  20. 78 FR 65610 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... From the Federal Register Online via the Government Publishing Office CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD Sunshine Act Meeting TIME AND DATE: November 14, 2013, 10:30 a.m.-1:30 p.m. CST. PLACE: Radisson Hotel & Conference Center, Banquet Room 5, 200 S. Bell School Road, Rockford, IL 61108. STATUS: Open to the public. MATTERS TO...

  1. 78 FR 78811 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD Sunshine Act Meeting TIME AND DATE: January 15, 2014, 6:30 p.m.-8:30 p.m. PST. PLACE: City Council Chambers, Civic Center Campus, 440 Civic Center Plaza, Richmond, CA 94804. STATUS: Open to the public. Matters To Be Considered...

  2. 78 FR 41908 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... From the Federal Register Online via the Government Publishing Office CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD Sunshine Act Meeting TIME AND DATE: July 25, 2013, 9:30 a.m.-4:30 p.m. EDT. PLACE: Ronald Reagan Building and International Trade Center, Horizon Room, 1300 Pennsylvania Avenue NW., Washington, DC 20004. STATUS: Open to the...

  3. The CounterACT Research Network

    PubMed Central

    Jett, David A.; Yeung, David T.

    2010-01-01

    The National Institutes of Health has developed a comprehensive research program that includes research centers of excellence, individual research projects, small business projects, contracts, and interagency agreements to conduct basic, translational, and clinical research aimed at the discovery and/or identification of better medical countermeasures against chemical threat agents. Chemical threats include chemical warfare agents, toxic industrial and agricultural chemicals, and toxins and other chemicals that could be used intentionally as an act of terror or by large-scale accidents or natural disasters. The overarching goal of this research program is to enhance our medical response capabilities during an emergency. The program is named Countermeasures Against Chemical Threats (CounterACT). It supports translational research, applying ideas, insights, and discoveries generated through basic scientific inquiry to the treatment or prevention of mortality and morbidity caused by chemical threat agents. The categories of research supported under this program include creation and development of screening assays and animal models for therapy development, identification of candidate therapeutics, obtaining preliminary proof-of-principle data on the efficacy of candidate therapeutics, advanced efficacy and preclinical safety studies with appropriate animal models using Good Laboratory Practices (GLP), and clinical studies, including clinical trials with new drugs. Special consideration is given to research relevant to people who are particularly vulnerable, including the young, the elderly, and individuals with pre-existing medical conditions. PMID:20601628

  4. ACT and College Success

    ERIC Educational Resources Information Center

    Bleyaert, Barbara

    2010-01-01

    What is the relationship between ACT scores and success in college? For decades, admissions policies in colleges and universities across the country have required applicants to submit scores from a college entrance exam, most typically the ACT (American College Testing) or SAT (Scholastic Aptitude Test). This requirement suggests that high school…

  5. Review of organic nitrile incineration at the Toxic Substances Control Act Incinerator

    SciTech Connect

    1997-10-01

    Lockheed Martin Energy Systems, Inc. (LMES) operates the East Tennessee Technology Park (ETTP), formerly called the Oak Ridge K-25 Site, where uranium was enriched under contract with the US Department of Energy (DOE). Currently, ETTP missions include environmental management, waste management (WM), and the development of new technologies. As part of its WM mission, ETTP operates the TSCA (Toxic Substances Control Act) Incinerator (TSCAI) for treatment of hazardous waste and polychlorinated biphenyls (PCBs) contaminated with low-level radioactivity. Beginning in the autumn of 1995, employees from diverse ETTP buildings and departments reported experiencing headaches, fatigue, depression, muscle aches, sleeplessness, and muscle tremors. These symptoms were judged by a physician in the ETTP Health Services Department to be consistent with chronic exposures to hydrogen cyanide (HCN). The National Institute for Occupational Safety and Health (NIOSH) was called in to perform a health hazard evaluation to ascertain whether the employees` illnesses were in fact caused by occupational exposure to HCN. The NIOSH evaluation found no patterns for employees` reported symptoms with respect to work location or department. NIOSH also conducted a comprehensive air sampling study, which did not detect airborne cyanides at the ETTP. Employees, however, expressed concerns that the burning of nitrile-bearing wastes at the TSCAI might have produced HCN as a combustion product. Therefore, LMES and DOE established a multidisciplinary team (TSCAI Technical Review Team) to make a more detailed review of the possibility that combustion of nitrile-bearing wastes at the TSCAI might have either released nitriles or created HCN as a product of incomplete combustion (PIC).

  6. 21 CFR 1310.13 - Exemption of chemical mixtures; application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exemption of chemical mixtures; application. 1310... REPORTS OF LISTED CHEMICALS AND CERTAIN MACHINES § 1310.13 Exemption of chemical mixtures; application. (a... application of all or any part of the Act a chemical mixture consisting of two or more chemical components,...

  7. 40 CFR 766.25 - Chemical substances for testing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Chemical substances for testing. 766... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.25 Chemical substances for testing. (a) Listing of chemical substances. Chemical...

  8. 40 CFR 766.25 - Chemical substances for testing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Chemical substances for testing. 766... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.25 Chemical substances for testing. (a) Listing of chemical substances. Chemical...

  9. 40 CFR 766.25 - Chemical substances for testing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Chemical substances for testing. 766... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.25 Chemical substances for testing. (a) Listing of chemical substances. Chemical...

  10. 40 CFR 766.25 - Chemical substances for testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Chemical substances for testing. 766... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.25 Chemical substances for testing. (a) Listing of chemical substances. Chemical...

  11. 40 CFR 766.25 - Chemical substances for testing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Chemical substances for testing. 766... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.25 Chemical substances for testing. (a) Listing of chemical substances. Chemical...

  12. 16 CFR 1507.2 - Prohibited chemicals.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Prohibited chemicals. 1507.2 Section 1507.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS FIREWORKS DEVICES § 1507.2 Prohibited chemicals. Fireworks devices shall not contain any of the following chemicals: (a) Arsenic sulfide,...

  13. Assertive Community Treatment (ACT)

    MedlinePlus

    ... community treatment? Assertive community treatment (ACT) is a model of psychiatric care that can be very effective ... it the most. Similar to the “treatment team” model of an inpatient psychiatric unit, which includes nurses, ...

  14. The ACTS propagation program

    NASA Technical Reports Server (NTRS)

    Chakraborty, Dayamoy; Davarian, Faramaz

    1991-01-01

    The purpose of the Advanced Communications Technology Satellite (ACTS) is to demonstrate the feasibility of the Ka-band (20 and 30 GHz) spectrum for satellite communications, as well as to help maintain U.S. leadership in satellite communications. ACTS incorporates such innovative schemes as time division multiple access (TDMA), microwave and baseband switching, onboard regeneration, and adaptive application of coding during rain-fade conditions. The success or failure of the ACTS experiment will depend on how accurately the rain-fade statistics and fade dynamics can be predicted in order to derive an appropriate algorithm that will combat weather vagaries, specifically for links with small terminals, such as very small aperture terminals (VSAT's) where the power margin is a premium. This article describes the planning process and hardware development program that will comply with the recommendations of the ACTS propagation study groups.

  15. ACTS mobile SATCOM experiments

    NASA Technical Reports Server (NTRS)

    Abbe, Brian S.; Frye, Robert E.; Jedrey, Thomas C.

    1993-01-01

    Over the last decade, the demand for reliable mobile satellite communications (satcom) for voice, data, and video applications has increased dramatically. As consumer demand grows, the current spectrum allocation at L-band could become saturated. For this reason, NASA and the Jet Propulsion Laboratory are developing the Advanced Communications Technology Satellites (ACTS) mobile terminal (AMT) and are evaluating the feasibility of K/Ka-band (20/30 GHz) mobile satcom to meet these growing needs. U.S. industry and government, acting as co-partners, will evaluate K/Ka-band mobile satcom and develop new technologies by conducting a series of applications-oriented experiments. The ACTS and the AMT testbed will be used to conduct these mobile satcom experiments. The goals of the ACTS Mobile Experiments Program and the individual experiment configurations and objectives are further presented.

  16. The ACTS propagation program

    NASA Technical Reports Server (NTRS)

    Chakraborty, D.; Davarian, Faramaz

    1992-01-01

    The success or failure of the ACTS experiment will depend on how accurately the rain-fade statistics and fade dynamics can be predicted in order to derive an appropriate algorithm that will combat weather vagaries, specifically for links with small terminals, such as very small aperture terminals (VSAT's) where the power margin is a premium. The planning process and hardware development program that will comply with the recommendations of the ACTS propagation study groups are described.

  17. Safe drinking water act

    SciTech Connect

    Calabrese, E.J.; Gilbert, C.E. )

    1989-01-01

    This book covers drinking water regulations such as disinfectant by-products, synthetic organics, inorganic chemicals, microbiological contaminants, volatile organic chemicals, radionuclides, fluoride, toxicological approaches to setting new national drinking water regulations, and trihalomethanes. Gives organic and inorganic compounds scheduled to be regulated in 1989 and candidates for the 1990s regulations.

  18. Biomass - chemicals

    SciTech Connect

    Kovaly, K.A.

    1982-08-01

    A host of industrial chemicals, specialty items, solvents, plastics, elastomers, fibers and films can be produced from agricultural crops, wood, paper mill wastes, food processing wastes, municipal waste and sewage. Existing chemical processes based on readily renewable plant materials are reviewed. These include ethanol and acetone-butanol fermentations, oilseed chemicals, furfural and cellulosics. (Refs. 16).

  19. Chemical sensor

    NASA Technical Reports Server (NTRS)

    Rauh, R. David (Inventor)

    1990-01-01

    A sensor for detecting a chemical substance includes an insertion element having a structure which enables insertion of the chemical substance with a resulting change in the bulk electrical characteristics of the insertion element under conditions sufficient to permit effective insertion; the change in the bulk electrical characteristics of the insertion element is detected as an indication of the presence of the chemical substance.

  20. The CEO's second act.

    PubMed

    Nadler, David A

    2007-01-01

    When a CEO leaves because of performance problems, the company typically recruits someone thought to be better equipped to fix what the departing executive couldn't--or wouldn't. The board places its confidence in the new person because of the present dilemma's similarity to some previous challenge that he or she dealt with successfully. But familiar problems are inevitably succeeded by less familiar ones, for which the specially selected CEO is not quite so qualified. More often than not, the experiences, skills, and temperament that yielded triumph in Act I turn out to be unequal to Act II's difficulties. In fact, the approaches that worked so brilliantly in Act I may be the very opposite of what is needed in Act II. The CEO has four choices: refuse to change, in which case he or she will be replaced; realize that the next act requires new skills and learn them; downsize or circumscribe his or her role to compensate for deficiencies; or line up a successor who is qualified to fill a role to which the incumbent's skills and interests are no longer suited. Hewlett-Packard's Carly Fiorina exemplifies the first alternative; Merrill Lynch's Stanley O'Neal the second; Google's Sergey Brin and Larry Page the third; and Quest Diagnostics' Ken Freeman the fourth. All but the first option are reasonable responses to the challenges presented in the second acts of most CEOs' tenures. And all but the first require a power of observation, a propensity for introspection, and a strain of humility that are rare in the ranks of the very people who need those qualities most. There are four essential steps executives can take to discern that they have entered new territory and to respond accordingly: recognition that their leadership style and approach are no longer working; acceptance of others' advice on why performance is faltering; analysis and understanding of the nature of the Act II shift; and, finally, decision and action. PMID:17286076

  1. 75 FR 70929 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... international network of laboratories that can respond to acts of biological, chemical, or radiological... additional information from LRN Member Laboratories in regards to biological or chemical terrorism... changes, LRN may also query laboratories to see if they have already purchased equipment to support...

  2. The ACTS multibeam antenna

    NASA Astrophysics Data System (ADS)

    Regier, Frank A.

    1992-06-01

    The Advanced Communications Technology Satellite (ACTS) to be launched in 1993 is briefly introduced. Its multibeam antenna, consisting of electrically similar 30 GHz receive and 20 GHz transmit offset Cassegrain systems, both utilizing orthogonal polarizations, is described. Dual polarization is achieved by using one feed assembly for each polarization in conjunction with nested front and back subreflectors, the gridded front subreflector acting as a window for one polarization and a reflector for the other. The antennas produce spot beams with approximately 0.3 degree beamwidth and gains of approximately 50 dbi. High surface accuracy and high edge taper produce low sidelobe levels and high cross-polarization isolation. A brief description is given of several Ka-band components fabricated for ACTS. These include multiflare antenna feedhorns, beam-forming networks utilizing latching ferrite waveguide switches, a 30 GHz HEMT low-noise amplifier and a 20 GHz TWT power amplifier.

  3. The ACTS multibeam antenna

    NASA Technical Reports Server (NTRS)

    Regier, Frank A.

    1992-01-01

    The Advanced Communications Technology Satellite (ACTS) to be launched in 1993 is briefly introduced. Its multibeam antenna, consisting of electrically similar 30 GHz receive and 20 GHz transmit offset Cassegrain systems, both utilizing orthogonal polarizations, is described. Dual polarization is achieved by using one feed assembly for each polarization in conjunction with nested front and back subreflectors, the gridded front subreflector acting as a window for one polarization and a reflector for the other. The antennas produce spot beams with approximately 0.3 degree beamwidth and gains of approximately 50 dbi. High surface accuracy and high edge taper produce low sidelobe levels and high cross-polarization isolation. A brief description is given of several Ka-band components fabricated for ACTS. These include multiflare antenna feedhorns, beam-forming networks utilizing latching ferrite waveguide switches, a 30 GHz HEMT low-noise amplifier and a 20 GHz TWT power amplifier.

  4. Affordable Care Act.

    PubMed

    Rak, Sofija; Coffin, Janis

    2013-01-01

    The Patient Protection and Affordable Care Act of 2010 (PPACA), although a subject of much debate in the Unites States, was enacted on March 23, 2010, and upheld by the Supreme Court on June 28, 2012. This act advocates that "healthcare is a right, not a privilege." The main goals of PPACA are to minimize the number of uninsured Americans and make healthcare available to everyone at an affordable price. The Congressional Budget Office has determined that 94% of Americans will have healthcare coverage while staying under the $900 billion limit that President Barack Obama established by bending the healthcare cost curve and reducing the deficit over the next 10 years. PMID:23767130

  5. [Chemical weapons and chemical terrorism].

    PubMed

    Nakamura, Katsumi

    2005-10-01

    Chemical Weapons are kind of Weapons of Mass Destruction (WMD). They were used large quantities in WWI. Historically, large quantities usage like WWI was not recorded, but small usage has appeared now and then. Chemical weapons are so called "Nuclear weapon for poor countrys" because it's very easy to produce/possession being possible. They are categorized (1) Nerve Agents, (2) Blister Agents, (3) Cyanide (blood) Agents, (4) Pulmonary Agents, (5) Incapacitating Agents (6) Tear Agents from the viewpoint of human body interaction. In 1997 the Chemical Weapons Convention has taken effect. It prohibits chemical weapons development/production, and Organization for the Prohibition of Chemical Weapons (OPCW) verification regime contributes to the chemical weapons disposal. But possibility of possession/use of weapons of mass destruction by terrorist group represented in one by Matsumoto and Tokyo Subway Sarin Attack, So new chemical terrorism countermeasures are necessary. PMID:16296384

  6. Acts of Endearment

    PubMed Central

    Stephens, G. Gayle

    1992-01-01

    Legitimate and clinically useful affection between physicians and patients can be nurtured by attending to duties enjoined by traditional codes of ethics. Three acts of endearment have special importance for today's family physicians: smoothing the bed of death; keeping patients' secrets; and not abandoning patients on account of incurability. PMID:20469528

  7. Respect for Acting.

    ERIC Educational Resources Information Center

    Hagen, Uta

    This book, based on the author's experience as a professional actress, is divided into three sections. The first part, "The Actor," deals with techniques the actor uses to function physically, verbally, and emotionally and discusses the actor's concept of himself and the art of acting. The second part, "The Object Exercises," consists of a series…

  8. Acting like a Pro

    ERIC Educational Resources Information Center

    Walker, Marlon A.

    2012-01-01

    The Saturday morning acting class in the Pearson Hall auditorium at Miles College boasts the school's highest attendance all year. The teacher, actress Robin Givens, was a lure few students--and others from surrounding areas--could resist. Some came to learn about their prospective field from a professional. Others were there for pointers to…

  9. Improving America's Schools Act

    NASA Technical Reports Server (NTRS)

    Cradler, John; Bridgforth, Elizabeth

    1995-01-01

    The Improving America's Schools ACT (IASA) emphasizes coherent systemic education reform, with Goals 2000 setting common standards for IASA and the recently authorized School-to-Work Program. IASA addresses the need to raise academic achievement, increase opportunities to learn, improve professional development, increase community involvement, utilize instructional applications of technology, and improve assessment, and allow more local flexibility in the use of funds.

  10. The USA PATRIOT Act.

    ERIC Educational Resources Information Center

    Minow, Mary; Coyle, Karen; Kaufman, Paula

    2002-01-01

    Explains the USA PATRIOT (Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism) Act, passed after the September 11 terrorist attacks, and its implications for libraries and patron records. Considers past dealings with the FBI; court orders; search warrants; wiretaps; and subpoenas. Includes:…

  11. ACTS Mobile Terminals

    NASA Technical Reports Server (NTRS)

    Abbe, Brian S.; Agan, Martin J.; Jedrey, Thomas C.

    1997-01-01

    The development of the Advanced Communications Technology Satellite (ACTS) Mobile Terminal (AMT) and its follow-on, the Broadband Aeronautical Terminal (BAT), have provided an excellent testbed for the evaluation of K- and Ka-band mobile satellite communications systems. An overview of both of these terminals is presented in this paper.

  12. Chemical microsensors

    DOEpatents

    Li, DeQuan; Swanson, Basil I.

    1995-01-01

    An article of manufacture is provided including a substrate having an oxide surface layer and a selective thin film of a cyclodextrin derivative chemically bound upon said substrate, said film is adapted for the inclusion of a selected organic compound therewith. Such an article can be either a chemical sensor capable of detecting a resultant mass change from inclusion of the selected organic compound or a chemical separator capable of reversibly selectively separating a selected organic compound.

  13. [Cutaneous absorption of chemicals].

    PubMed

    Schröder, J

    1986-09-01

    Chemicals have become indispensible for the maintenance of health in animals and man. The route of administration of each medicament is decided by factors such as site of desired action, chemistry of the active ingredient, age and species of the patient, and frequency of administration (or desired duration of activity). In situations where the oral and hypodermic routes, which are used most frequently, are inadequate or unsatisfactory, dermal application can provide a valuable alternative method to achieve systemic activity. Examples of formulations currently available for dermal application contain diverse chemicals and are intended for a variety of purposes, such as crufomate against cattle grubs, fenthion against cattle lice, levamisole against gastrointestinal nematodes, nitroglycerine for angina pectoris, and scopolamine for motion sickness. The skin acts as a barrier to penetration by chemicals and micro-organisms by virtue of its morphology and chemical composition. Chemicals which do penetrate, do not necessarily pass through the appendages (hair follicles and gland ducts), but mostly penetrate through the interjacent epidermis, either through the cells, or via the intracellular spaces. These spaces have recently been shown by electron microscopy to be filled by an amorphous substance which exudes on the skin surface in convex ridges. This substance has a lipid nature, but is not hydrophobic as is often accepted. For a chemical to be able to penetrate the skin, it must be partially water and lipid soluble, polar, and weakly ionizing. A variety of factors can possibly affect the permeability of skin for a chemical. These include species differences in morphology (skin thickness, tightness of intercellular junctions, density of hair follicles and other appendages), biochemistry, and physiology; seasonal and climatic variations; and differences between breeds and genders. Species differences in skin permeability are largely unpredictable and inconsistent. An

  14. Chemical Agents

    MedlinePlus

    ... glycol Hydrazine Hydrofluoric acid Hydrogen chloride Lewisite Melamine Mercury Methyl bromide Methyl isocyanate Nicotine Nitrogen mustard Opioids ... L-3) Long-acting anticoagulant (super warfarin) M Mercury Methyl bromide Methyl isocyanate Mustard gas (H) (sulfur ...

  15. 40 CFR 799.19 - Chemical imports and exports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the requirements of 40 CFR part 707. ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false Chemical imports and exports. 799.19... CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING...

  16. 40 CFR 799.19 - Chemical imports and exports.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the requirements of 40 CFR part 707. ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Chemical imports and exports. 799.19... CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING...

  17. 40 CFR 799.19 - Chemical imports and exports.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the requirements of 40 CFR part 707. ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Chemical imports and exports. 799.19... CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING...

  18. 40 CFR 799.19 - Chemical imports and exports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the requirements of 40 CFR part 707. ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Chemical imports and exports. 799.19... CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING...

  19. 40 CFR 799.19 - Chemical imports and exports.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the requirements of 40 CFR part 707. ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false Chemical imports and exports. 799.19... CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND MIXTURE TESTING...

  20. Acts of kindness and acts of novelty affect life satisfaction.

    PubMed

    Buchanan, Kathryn E; Bardi, Anat

    2010-01-01

    The present experiment was designed to establish the effects of acts of kindness and acts of novelty on life satisfaction. Participants aged 18-60 took part on a voluntary basis. They were randomly assigned to perform either acts of kindness, acts of novelty, or no acts on a daily basis for 10 days. Their life satisfaction was measured before and after the 10-day experiment. As expected, performing acts of kindness or acts of novelty resulted in an increase in life satisfaction. PMID:20575332

  1. Thyroid disrupting chemicals: Mechanisms and mixtures

    EPA Science Inventory

    Environmental contaminants are known to act as thyroid disrupting chemicals (TDCs). Broadly defined, TDCs are xenobiotics that alter the structure or function of the thyroid gland, alter regulatory enzymes associated with thyroid hormone (TH) homeostasis, or change circulating o...

  2. Continuing Chemical Facilities Antiterrorism Security Act of 2011

    THOMAS, 112th Congress

    Sen. Collins, Susan M. [R-ME

    2011-03-03

    10/20/2011 By Senator Lieberman from Committee on Homeland Security and Governmental Affairs filed written report. Report No. 112-90. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. Protecting Communities from Chemical Explosions Act of 2013

    THOMAS, 113th Congress

    Sen. Lautenberg, Frank R. [D-NJ

    2013-04-25

    04/25/2013 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. Biological and Chemical Security

    SciTech Connect

    Fitch, P J

    2002-12-19

    The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) Chemical and Biological Nonproliferation Program (also known as CBNP). In 2002, the Department of Homeland Security was formed. The NNSA CBNP and many of the LLNL CBNP activities are being transferred as the new Department becomes operational. LLNL has a long history in national security including nonproliferation of weapons of mass destruction. In biology, LLNL had a key role in starting and implementing the Human Genome Project and, more recently, the Microbial Genome Program. LLNL has over 1,000 scientists and engineers with relevant expertise in biology, chemistry, decontamination, instrumentation, microtechnologies, atmospheric modeling, and field experimentation. Over 150 LLNL scientists and engineers work full time on chemical and biological national security projects.

  5. Chemical preconcentrator

    DOEpatents

    Manginell, Ronald P.; Frye-Mason, Gregory C.

    2001-01-01

    A chemical preconcentrator is disclosed with applications to chemical sensing and analysis. The preconcentrator can be formed by depositing a resistive heating element (e.g. platinum) over a membrane (e.g. silicon nitride) suspended above a substrate. A coating of a sorptive material (e.g. a microporous hydrophobic sol-gel coating or a polymer coating) is formed on the suspended membrane proximate to the heating element to selective sorb one or more chemical species of interest over a time period, thereby concentrating the chemical species in the sorptive material. Upon heating the sorptive material with the resistive heating element, the sorbed chemical species are released for detection and analysis in a relatively high concentration and over a relatively short time period. The sorptive material can be made to selectively sorb particular chemical species of interest while not substantially sorbing other chemical species not of interest. The present invention has applications for use in forming high-sensitivity, rapid-response miniaturized chemical analysis systems (e.g. a "chem lab on a chip").

  6. Chemical sensors

    DOEpatents

    Lowell, Jr., James R.; Edlund, David J.; Friesen, Dwayne T.; Rayfield, George W.

    1991-01-01

    Sensors responsive to small changes in the concentration of chemical species are disclosed, comprising (a) a mechanochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment, operatively coupled to (b) a transducer capable of directly converting said expansion or contraction to a measurable electrical response.

  7. Chemical sensors

    DOEpatents

    Lowell, J.R. Jr.; Edlund, D.J.; Friesen, D.T.; Rayfield, G.W.

    1991-07-02

    Sensors responsive to small changes in the concentration of chemical species are disclosed. The sensors comprise a mechanochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment. They are operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical response. 9 figures.

  8. Chemical Peels

    MedlinePlus

    ... the complications or potential side effects of a chemical peel? Temporary or permanent change in skin color, particularly for women on birth control pills, who subsequently become pregnant or have a history of brownish facial ... after having a chemical peel? All peels require some follow-up care: ...

  9. Chemical Emergencies

    MedlinePlus

    ... agents such as sarin and VX. Many hazardous chemicals are used in industry - for example, chlorine, ammonia, and benzene. Some can be made from everyday items such as household cleaners. Although there are no guarantees of safety during a chemical emergency, you can take actions to protect yourself. ...

  10. ACTS of Education

    NASA Technical Reports Server (NTRS)

    Bauer, Robert; Krawczyk, Richard; Gargione, Frank; Kruse, Hans; Vrotsos, Pete (Technical Monitor)

    2002-01-01

    Now in its ninth year of operations, the Advanced Communications Technology Satellite (ACTS) program has continued, although since May 2000 in a new operations arrangement involving a university based consortium, the Ohio Consortium for Advanced Communications Technology (OCACT), While NASA has concluded its experimental intentions of ACTS, the spacecraft's ongoing viability has permitted its further operations to provide educational opportunities to engineering and communications students interested in satellite operations, as well as a Ka-band test bed for commercial interests in utilizing Kaband space communications. The consortium has reached its first year of operations. This generous opportunity by NASA has already resulted in unique educational opportunities for students in obtaining "hands-on" experience, such as, in satellite attitude control. An update is presented on the spacecraft and consortium operations.

  11. ACTS TDMA network control

    NASA Astrophysics Data System (ADS)

    Inukai, T.; Campanella, S. J.

    This paper presents basic network control concepts for the Advanced Communications Technology Satellite (ACTS) System. Two experimental systems, called the low-burst-rate and high-burst-rate systems, along with ACTS ground system features, are described. The network control issues addressed include frame structures, acquisition and synchronization procedures, coordinated station burst-time plan and satellite-time plan changes, on-board clock control based on ground drift measurements, rain fade control by means of adaptive forward-error-correction (FEC) coding and transmit power augmentation, and reassignment of channel capacities on demand. The NASA ground system, which includes a primary station, diversity station, and master control station, is also described.

  12. Multiple-mask chemical etching

    NASA Technical Reports Server (NTRS)

    Cannon, D. L.

    1969-01-01

    Multiple masking techniques use lateral etching to reduce the total area of the high etch-rate oxide exposed to the chemical etchant. One method uses a short-term etch to remove the top layer from the silicon oxide surface, another acts before the top layer is grown.

  13. [Patients' Rights Act].

    PubMed

    Haier, A J

    2016-09-01

    The new Patients' Rights Act does not reflect rights of patients as professional obligations of physicians for the first time. It adopted common longtime jurisdiction, but in some respects it is going beyond. This law clearly extended the documentation requirements of physicians, especially concerning the extent of documentation. In surgical fields the requirements for enlightening physicians were more strongly worded than in previous jurisdiction. In medical facilities it is now mandatory to establish an internal quality management system. PMID:27626814

  14. Toxic Substances Control Act

    SciTech Connect

    Not Available

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  15. ACTE Wing Loads Analysis

    NASA Technical Reports Server (NTRS)

    Horn, Nicholas R.

    2015-01-01

    The Adaptive Compliant Trailing Edge (ACTE) project modified a Gulfstream III (GIII) aircraft with a new flexible flap that creates a seamless transition between the flap and the wing. As with any new modification, it is crucial to ensure that the aircraft will not become overstressed in flight. To test this, Star CCM a computational fluid dynamics (CFD) software program was used to calculate aerodynamic data for the aircraft at given flight conditions.

  16. Freedom of Information Act

    USGS Publications Warehouse

    Newman, D.J.

    2012-01-01

    The Freedom of Information Act( FOIA), 5 U.S.C.§ 552, as amended, generally provides that any person has a right to request access to Federal agency records. The USGS proactively promotes information disclosure as inherent to its mission of providing objective science to inform decisionmakers and the general public. USGS scientists disseminate up-to-date and historical scientific data that are critical to addressing national and global priorities.

  17. The ACTS multibeam antenna

    NASA Astrophysics Data System (ADS)

    Regier, Frank A.

    1992-04-01

    The Advanced Communications Technology Satellite (ACTS) to be launched in 1993 introduces several new technologies including a multibeam antenna (MBA) operating at Ka-band. The satellite is introduced briefly, and then the MBA, consisting of electrically similar 30 GHz received and 20 GHz transmit offset Cassegrain systems utilizing orthogonal linear polarizations, is described. Dual polarization is achieved by using one feed assembly for each polarization in conjunction with nested front and back subreflectors, the gridded front subreflector acting as a window for one polarization and a reflector for the other. The antennas produce spot beams with approximately 0.3 deg beamwidth and gains of approximately 50 dbi. High surface accuracy and high edge taper produce low sidelobe levels and high cross-polarization isolation. A brief description is given of several Ka-band components fabricated for ACTS. These include multiflare antenna feedhorns, beam-forming networks utilizing latching ferrite waveguide switches, a 30 GHz high mobility electron transmitter (HEMT) low-noise amplifier and a 20 GHz TWT power amplifier.

  18. The ACTS multibeam antenna

    NASA Technical Reports Server (NTRS)

    Regier, Frank A.

    1992-01-01

    The Advanced Communications Technology Satellite (ACTS) to be launched in 1993 introduces several new technologies including a multibeam antenna (MBA) operating at Ka-band. The satellite is introduced briefly, and then the MBA, consisting of electrically similar 30 GHz received and 20 GHz transmit offset Cassegrain systems utilizing orthogonal linear polarizations, is described. Dual polarization is achieved by using one feed assembly for each polarization in conjunction with nested front and back subreflectors, the gridded front subreflector acting as a window for one polarization and a reflector for the other. The antennas produce spot beams with approximately 0.3 deg beamwidth and gains of approximately 50 dbi. High surface accuracy and high edge taper produce low sidelobe levels and high cross-polarization isolation. A brief description is given of several Ka-band components fabricated for ACTS. These include multiflare antenna feedhorns, beam-forming networks utilizing latching ferrite waveguide switches, a 30 GHz high mobility electron transmitter (HEMT) low-noise amplifier and a 20 GHz TWT power amplifier.

  19. 40 CFR 766.38 - Reporting on precursor chemical substances.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Reporting on precursor chemical... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.38 Reporting on precursor chemical substances. (a) Identification of precursor chemical...

  20. 40 CFR 766.38 - Reporting on precursor chemical substances.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Reporting on precursor chemical... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.38 Reporting on precursor chemical substances. (a) Identification of precursor chemical...

  1. 40 CFR 766.38 - Reporting on precursor chemical substances.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Reporting on precursor chemical... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.38 Reporting on precursor chemical substances. (a) Identification of precursor chemical...

  2. 40 CFR 766.38 - Reporting on precursor chemical substances.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Reporting on precursor chemical... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.38 Reporting on precursor chemical substances. (a) Identification of precursor chemical...

  3. 40 CFR 766.38 - Reporting on precursor chemical substances.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Reporting on precursor chemical... SUBSTANCES CONTROL ACT DIBENZO-PARA-DIOXINS/DIBENZOFURANS Specific Chemical Testing/Reporting Requirements § 766.38 Reporting on precursor chemical substances. (a) Identification of precursor chemical...

  4. Unnecessary Chemicals

    ERIC Educational Resources Information Center

    Johnson, Anita

    1978-01-01

    Discusses the health hazards resulting from chemical additions of many common products such as cough syrups, food dyes, and cosmetics. Steps being taken to protect consumers from these health hazards are included. (MDR)

  5. Chemical geodynamics

    NASA Astrophysics Data System (ADS)

    Zindler, A.; Hart, S.

    Consideration is given to the following three principal boundary conditions relating to the nature and development of chemical structure in the earth's mantle: (1) inferred scale lengths for mantle chemical heterogeneities, (2) interrelationships of the various isotopic tracers, and (3) the bulk composition of the earth. These boundary conditions are integrated with geophysical constraints in order to evaluate models for the development of the physical and chemical structure of the mantle. Data indicate that: (1) km-size heterogeneities can survive diffusive equilibrium for billions of years; (2) the mantle is chemically heterogeneous on both very small and very large scales; (3) isotopic heterogeneities in the mantle require the existence of four 'end-member' components (DMM, HIMU, EM I, and EM II) and are consistent with the existence of at least two additional components (BSE, PREMA); and (4) primitive undepleted mantle can made up no more than about 55 percent of the total mantle.

  6. Chemical sensors

    DOEpatents

    Lowell, Jr., James R.; Edlund, David J.; Friesen, Dwayne T.; Rayfield, George W.

    1992-01-01

    Sensors responsive to small changes in the concentration of chemical species are disclosed, comprising a mechanicochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment, either operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical or optical response, or adhered to a second inert polymeric strip, or doped with a conductive material.

  7. Chemical sensors

    DOEpatents

    Lowell, J.R. Jr.; Edlund, D.J.; Friesen, D.T.; Rayfield, G.W.

    1992-06-09

    Sensors responsive to small changes in the concentration of chemical species are disclosed, comprising a mechanicochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment, either operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical or optical response, or adhered to a second inert polymeric strip, or doped with a conductive material. 12 figs.

  8. Quick acting gimbal joint

    NASA Technical Reports Server (NTRS)

    Wood, William B. (Inventor); Krch, Gary D. (Inventor)

    1993-01-01

    The present invention relates to an adjustable linkage assembly for selectively retaining the position of one member pivotable with respect to another member. More specifically, the invention relates to a linkage assembly commonly referred to as a gimbal joint, and particularly to a quick release or quick acting gimbal joint. The assembly is relatively simple in construction, compact in size, and has superior locking strength in any selected position. The device can be quickly and easily actuated, without separate tooling, by inexperienced personnel or by computer controlled equipment. It also is designed to prevent inadvertent actuation.

  9. 40 CFR 799.9780 - TSCA immunotoxicity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 CFR 799.9346. The exposure time for the anti-SRBC test shall be at least 28 days. (6) Observation... levels. (3) Test report. In addition to the reporting requirements as specified under 40 CFR part 792... study shall be conducted in compliance with the 40 CFR Part 792—Good Laboratory Practice. (j)...

  10. 40 CFR 799.9420 - TSCA carcinogenicity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Test report. (i) In addition to the reporting requirements as specified under 40 CFR part 792, subpart... equipment. The study shall be conducted in compliance with 40 CFR part 792—Good Laboratory Practice... periodically during the study. Statistically randomized samples of the mixture should be analyzed to...

  11. 40 CFR 799.9420 - TSCA carcinogenicity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Test report. (i) In addition to the reporting requirements as specified under 40 CFR part 792, subpart... equipment. The study shall be conducted in compliance with 40 CFR part 792—Good Laboratory Practice... periodically during the study. Statistically randomized samples of the mixture should be analyzed to...

  12. 40 CFR 799.9780 - TSCA immunotoxicity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 CFR 799.9346. The exposure time for the anti-SRBC test shall be at least 28 days. (6) Observation... levels. (3) Test report. In addition to the reporting requirements as specified under 40 CFR part 792... study shall be conducted in compliance with the 40 CFR Part 792—Good Laboratory Practice. (j)...

  13. 40 CFR 799.9780 - TSCA immunotoxicity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 CFR 799.9346. The exposure time for the anti-SRBC test shall be at least 28 days. (6) Observation... levels. (3) Test report. In addition to the reporting requirements as specified under 40 CFR part 792... study shall be conducted in compliance with the 40 CFR Part 792—Good Laboratory Practice. (j)...

  14. 40 CFR 799.9420 - TSCA carcinogenicity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Test report. (i) In addition to the reporting requirements as specified under 40 CFR part 792, subpart... equipment. The study shall be conducted in compliance with 40 CFR part 792—Good Laboratory Practice... periodically during the study. Statistically randomized samples of the mixture should be analyzed to...

  15. 40 CFR 799.9780 - TSCA immunotoxicity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 CFR 799.9346. The exposure time for the anti-SRBC test shall be at least 28 days. (6) Observation... levels. (3) Test report. In addition to the reporting requirements as specified under 40 CFR part 792... study shall be conducted in compliance with the 40 CFR Part 792—Good Laboratory Practice. (j)...

  16. 40 CFR 799.9420 - TSCA carcinogenicity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Test report. (i) In addition to the reporting requirements as specified under 40 CFR part 792, subpart... equipment. The study shall be conducted in compliance with 40 CFR part 792—Good Laboratory Practice... periodically during the study. Statistically randomized samples of the mixture should be analyzed to...

  17. 40 CFR 799.9780 - TSCA immunotoxicity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 CFR 799.9346. The exposure time for the anti-SRBC test shall be at least 28 days. (6) Observation... levels. (3) Test report. In addition to the reporting requirements as specified under 40 CFR part 792... study shall be conducted in compliance with the 40 CFR Part 792—Good Laboratory Practice. (j)...

  18. 40 CFR 799.9420 - TSCA carcinogenicity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Test report. (i) In addition to the reporting requirements as specified under 40 CFR part 792, subpart... equipment. The study shall be conducted in compliance with 40 CFR part 792—Good Laboratory Practice... periodically during the study. Statistically randomized samples of the mixture should be analyzed to...

  19. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ...The Board of Governors of the Federal Reserve System (Board) is issuing a final rule to amend its regulation implementing the Privacy Act of 1974 (Privacy Act). The primary changes concern the waiver of copying fees charged to current and former Board employees, and applicants for Board employment, for access to their records under the Privacy Act; the amendment of special procedures for the......

  20. ACTS broadband aeronautical experiment

    NASA Technical Reports Server (NTRS)

    Abbe, Brian S.; Jedrey, Thomas C.; Estabrook, Polly; Agan, Martin J.

    1993-01-01

    In the last decade, the demand for reliable data, voice, and video satellite communication links between aircraft and ground to improve air traffic control, airline management, and to meet the growing demand for passenger communications has increased significantly. It is expected that in the near future, the spectrum required for aeronautical communication services will grow significantly beyond that currently available at L-band. In anticipation of this, JPL is developing an experimental broadband aeronautical satellite communications system that will utilize NASA's Advanced Communications Technology Satellite (ACTS) as a satellite of opportunity and the technology developed under JPL's ACTS Mobile Terminal (AMT) Task to evaluate the feasibility of using K/Ka-band for these applications. The application of K/Ka-band for aeronautical satellite communications at cruise altitudes is particularly promising for several reasons: (1) the minimal amount of signal attenuation due to rain; (2) the reduced drag due to the smaller K/Ka-band antennas (as compared to the current L-band systems); and (3) the large amount of available bandwidth. The increased bandwidth available at these frequencies is expected to lead to significantly improved passenger communications - including full-duplex compressed video and multiple channel voice. A description of the proposed broadband experimental system will be presented including: (1) applications of K/Ka-band aeronautical satellite technology to U.S. industry; (2) the experiment objectives; (3) the experiment set-up; (4) experimental equipment description; and (5) industrial participation in the experiment and the benefits.

  1. Affordable Care Act and Women

    MedlinePlus

    ... Privacy Policy FOIA Plain Writing Act No Fear Act Disclaimers Viewers & Players Assistant Secretary for Planning and Evaluation, Room 415F U.S. Department of Health and Human Services 200 Independence Avenue, SW Washington, D.C. ...

  2. Emergency Planning and Community Right-to-Know Act (EPCRA) requirements. CERCLA Information Brief

    SciTech Connect

    Dailey, R.

    1993-10-01

    The Emergency Planning and Community Right-to-Know Act (EPCRA), also known as Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA), requires regulated facilities to publicly disclose information about the chemicals they store, use, dispose of, or release. The information is used to encourage and support emergency planning for responding to chemical accidents and to provide local governments and the public with information about possible chemical hazards in their communities.

  3. The Nurse Reinvestment Act revisited.

    PubMed

    Luther, Ann P

    2007-01-01

    The United States is in the midst of a widely recognized critical nursing shortage. In 2002 the "Nurse Reinvestment Act" was passed with overwhelming bipartisan support in an effort to address this serious public health threat. The Act is due for reauthorization of funding in 2007. This paper provides a brief overview of the programs contained within the Act and describes practical ways in which members of the nursing community can take action to insure renewed support for the Act. PMID:17691598

  4. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Schertler, Ronald J.; Gedney, Richard T.

    1992-01-01

    An overview of the NASA ACTS program is presented. The key technologies of ACTS include spot beams, on-board baseband processing and routing, wide bandwidth (900 MHz), and Ka-band transponders. The discussion covers system description, current status of the spacecraft development, ACTS earth stations, NGS traffic terminal, USAT, land and aeronautical mobiles, high data rate and propagation receive only terminals, and ACTS experiments program.

  5. Chemical sensors

    SciTech Connect

    Hubbard, C.W.; Gordon, R.L.

    1987-05-01

    The revolution in analytical chemistry promised by recent developments in the field of chemical sensors has potential for significant positive impact on both research and production activities conducted by and for the Department of Energy. Analyses which were, in the past, performed only with a roomful of expensive equipment can now be performed with miniature solid-state electronic devices or small optical probes. Progress in the development of chemical sensors has been rapid, and the field is currently growing at a great rate. In accordance, Pacific Northwest Laboratory initiated a survey of recent literature so that contributors to active programs in research on analytical methods could be made aware of principles and applications of this new technology. This report presents the results of that survey. The sensors discussed here are divided into three types: micro solid-state devices, optical sensors, and piezoelectric crystal devices. The report is divided into three corresponding sections. The first section, ''Micro Solid-State Devices,'' discusses the design, operation, and application of electronic sensors that are produced in much the same way as standard solid-state electronic devices. The second section, ''Optrodes,'' covers the design and operation of chemical sensors that use fiber optics to detect chemically induced changes in optical properties. The final section, ''Piezoelectric Crystal Detectors,'' discusses two types of chemical sensors that depend on the changes in the properties of an oscillating piezoelectric crystal to detect the presence of certain materials. Advantages and disadvantages of each type of sensor are summarized in each section.

  6. ACT/SAT College Survey.

    ERIC Educational Resources Information Center

    Stafford, John E.

    1998-01-01

    Reports on findings of a survey designed to discover whether higher education institutions' admission standards accept SAT I or ACT and if there is preference for either, and whether ACT could be submitted in lieu of SAT II subject tests. Eighty-six percent of the reporting schools indicated no preference; 28 schools indicated that the ACT was an…

  7. Defining Acts of Journalistic Deception.

    ERIC Educational Resources Information Center

    Elliott, Deni; Culver, Charles M.

    To determine when, if ever, deceptive acts can be morally justified in investigative reporting, it is important to distinguish a deceptive act that is morally justified from an act that is not deceptive in the first place. This paper seeks to provide an account of what counts as deception and identify the kinds of journalistic practice that are…

  8. Chemical networks

    NASA Astrophysics Data System (ADS)

    Thi, Wing-Fai

    2015-09-01

    This chapter discusses the fundamental ideas of how chemical networks are build, their strengths and limitations. The chemical reactions that occur in disks combine the cold phase reactions used to model cold molecular clouds with the hot chemistry applied to planetary atmosphere models. With a general understanding of the different types of reactions that can occur, one can proceed in building a network of chemical reactions and use it to explain the abundance of species seen in disks. One on-going research subject is finding new paths to synthesize species either in the gas-phase or on grain surfaces. Specific formation routes for water or carbon monoxide are discussed in more details. 13th Lecture of the Summer School "Protoplanetary Disks: Theory and Modelling Meet Observations"

  9. ACTS mobile propagation campaign

    NASA Technical Reports Server (NTRS)

    Goldhirsh, Julius; Vogel, Wolfhard J.; Torrence, Geoffrey W.

    1994-01-01

    Preliminary results are presented for three propagation measurement campaigns involving a mobile receiving laboratory and 20 GHz transmissions from the Advanced Communications Technology Satellite (ACTS). Four 1994 campaigns were executed during weekly periods in and around Austin, Texas in February and May, in Central Maryland during March, and in Fairbanks, Alaska and environs in June. Measurements tested the following effects at 20 GHz: (1) attenuation due to roadside trees with and without foliage, (2) multipath effects for scenarios in which line-of-sight paths were unshadowed, (3) fades due to terrain and roadside obstacles, (4) fades due to structures in urban environs, (5) single tree attenuation, and (6) effects of fading at low elevation angles (8 deg in Fairbanks, Alaska) and high elevation angles (55 deg in Austin, Texas). Results presented here cover sampled measurements in Austin, Texas for foliage and non-foliage cases and in Central Maryland for non-foliage runs.

  10. FAST ACTING CURRENT SWITCH

    DOEpatents

    Batzer, T.H.; Cummings, D.B.; Ryan, J.F.

    1962-05-22

    A high-current, fast-acting switch is designed for utilization as a crowbar switch in a high-current circuit such as used to generate the magnetic confinement field of a plasma-confining and heat device, e.g., Pyrotron. The device particularly comprises a cylindrical housing containing two stationary, cylindrical contacts between which a movable contact is bridged to close the switch. The movable contact is actuated by a differential-pressure, airdriven piston assembly also within the housing. To absorb the acceleration (and the shock imparted to the device by the rapidly driven, movable contact), an adjustable air buffer assembly is provided, integrally connected to the movable contact and piston assembly. Various safety locks and circuit-synchronizing means are also provided to permit proper cooperation of the invention and the high-current circuit in which it is installed. (AEC)

  11. Triple acting radial seal

    DOEpatents

    Ebert, Todd A; Carella, John A

    2012-03-13

    A triple acting radial seal used as an interstage seal assembly in a gas turbine engine, where the seal assembly includes an interstage seal support extending from a stationary inner shroud of a vane ring, the interstage seal support includes a larger annular radial inward facing groove in which an outer annular floating seal assembly is secured for radial displacement, and the outer annular floating seal assembly includes a smaller annular radial inward facing groove in which an inner annular floating seal assembly is secured also for radial displacement. A compliant seal is secured to the inner annular floating seal assembly. The outer annular floating seal assembly encapsulates the inner annular floating seal assembly which is made from a very low alpha material in order to reduce thermal stress.

  12. Caught in the Act

    NASA Technical Reports Server (NTRS)

    2005-01-01

    5 September 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a dust devil caught in the act of creating a dark streak on the floor of the large, south mid-latitude crater, Mendel. Dozens of other dark streaks mark the paths of earlier dust devils. Dust devil streaks at southern middle and high latitudes are seasonal features; they are erased each winter by thin deposits of dust and frost, and they are re-created each spring and summer by new dust devils.

    Location near: 58.9oS, 199.4oW Image width: width: 3 km (1.9 mi) Illumination from: upper left Season: Southern Spring

  13. Delicious Chemicals.

    ERIC Educational Resources Information Center

    Barry, Dana M.

    This paper presents an approach to chemistry and nutrition that focuses on food items that people consider delicious. Information is organized according to three categories of food chemicals that provide energy to the human body: (1) fats and oils; (2) carbohydrates; and (3) proteins. Minerals, vitamins, and additives are also discussed along with…

  14. Chemical sensors

    SciTech Connect

    Janata, J.; Josowicz, M.; DeVaney, D.M. )

    1994-06-15

    This review of chemical sensors contains the following topics of interest: books and reviews; reviews of sensors by their type; fabrication and selectivity; data processing; thermal sensors; mass sensors (fabrication, gas sensors, and liquid sensors); electrochemical sensors (potentiometric sensors, amperometric sensors, and conductometric sensors); and optical sensors (fabrication, liquid sensors, biosensors, and gas sensors). 795 refs., 1 tab.

  15. Chemical Mahjong

    ERIC Educational Resources Information Center

    Cossairt, Travis J.; Grubbs, W. Tandy

    2011-01-01

    An open-access, Web-based mnemonic game is described whereby introductory chemistry knowledge is tested using mahjong solitaire game play. Several tile sets and board layouts are included that are themed upon different chemical topics. Introductory tile sets can be selected that prompt the player to match element names to symbols and metric…

  16. Programmability of Chemical Reaction Networks

    NASA Astrophysics Data System (ADS)

    Cook, Matthew; Soloveichik, David; Winfree, Erik; Bruck, Jehoshua

    Motivated by the intriguing complexity of biochemical circuitry within individual cells we study Stochastic Chemical Reaction Networks (SCRNs), a formal model that considers a set of chemical reactions acting on a finite number of molecules in a well-stirred solution according to standard chemical kinetics equations. SCRNs have been widely used for describing naturally occurring (bio)chemical systems, and with the advent of synthetic biology they become a promising language for the design of artificial biochemical circuits. Our interest here is the computational power of SCRNs and how they relate to more conventional models of computation. We survey known connections and give new connections between SCRNs and Boolean Logic Circuits, Vector Addition Systems, Petri nets, Gate Implementability, Primitive Recursive Functions, Register Machines, Fractran, and Turing Machines. A theme to these investigations is the thin line between decidable and undecidable questions about SCRN behavior.

  17. Fast-Acting Valve

    NASA Technical Reports Server (NTRS)

    Wojciechowski, Bogdan V. (Inventor); Pegg, Robert J. (Inventor)

    2003-01-01

    A fast-acting valve includes an annular valve seat that defines an annular valve orifice between the edges of the annular valve seat, an annular valve plug sized to cover the valve orifice when the valve is closed, and a valve-plug holder for moving the annular valve plug on and off the annular valve seat. The use of an annular orifice reduces the characteristic distance between the edges of the valve seat. Rather than this distance being equal to the diameter of the orifice, as it is for a conventional circular orifice, the characteristic distance equals the distance between the inner and outer radii (for a circular annulus). The reduced characteristic distance greatly reduces the gap required between the annular valve plug and the annular valve seat for the valve to be fully open, thereby greatly reducing the required stroke and corresponding speed and acceleration of the annular valve plug. The use of a valve-plug holder that is under independent control to move the annular valve plug between its open and closed positions is important for achieving controllable fast operation of the valve.

  18. Double acting bit holder

    DOEpatents

    Morrell, Roger J.; Larson, David A.; Ruzzi, Peter L.

    1994-01-01

    A double acting bit holder that permits bits held in it to be resharpened during cutting action to increase energy efficiency by reducing the amount of small chips produced. The holder consist of: a stationary base portion capable of being fixed to a cutter head of an excavation machine and having an integral extension therefrom with a bore hole therethrough to accommodate a pin shaft; a movable portion coextensive with the base having a pin shaft integrally extending therefrom that is insertable in the bore hole of the base member to permit the moveable portion to rotate about the axis of the pin shaft; a recess in the movable portion of the holder to accommodate a shank of a bit; and a biased spring disposed in adjoining openings in the base and moveable portions of the holder to permit the moveable portion to pivot around the pin shaft during cutting action of a bit fixed in a turret to allow front, mid and back positions of the bit during cutting to lessen creation of small chip amounts and resharpen the bit during excavation use.

  19. Acting to gain information

    NASA Technical Reports Server (NTRS)

    Rosenchein, Stanley J.; Burns, J. Brian; Chapman, David; Kaelbling, Leslie P.; Kahn, Philip; Nishihara, H. Keith; Turk, Matthew

    1993-01-01

    This report is concerned with agents that act to gain information. In previous work, we developed agent models combining qualitative modeling with real-time control. That work, however, focused primarily on actions that affect physical states of the environment. The current study extends that work by explicitly considering problems of active information-gathering and by exploring specialized aspects of information-gathering in computational perception, learning, and language. In our theoretical investigations, we analyzed agents into their perceptual and action components and identified these with elements of a state-machine model of control. The mathematical properties of each was developed in isolation and interactions were then studied. We considered the complexity dimension and the uncertainty dimension and related these to intelligent-agent design issues. We also explored active information gathering in visual processing. Working within the active vision paradigm, we developed a concept of 'minimal meaningful measurements' suitable for demand-driven vision. We then developed and tested an architecture for ongoing recognition and interpretation of visual information. In the area of information gathering through learning, we explored techniques for coping with combinatorial complexity. We also explored information gathering through explicit linguistic action by considering the nature of conversational rules, coordination, and situated communication behavior.

  20. ITC-CMA partnership and data needs for alkylphenols and ethoxylates

    USGS Publications Warehouse

    Rattner, B.A.; Rice, C.P.; Walker, J.D.

    1996-01-01

    The ITC has been an independent advisory committee to the EPA Administrator since enactment of the Toxics Substances Control Act (TSCA) in 1976. The ITC identifies and coordinates U.S. Government data needs for TSCA-regulable chemicals, and makes recommendations to the Administrator for priority testing consideration. Chemicals recommended by the ITC are added to the TSCA Priority Testing List that is revised semi-annually in Reports to the Administrator. In recent Reports, the ITC added alkylphenols (APs) and ethoxylates to the Priority Testing List. About 500 million pounds are produced annually for industrial processing, cleaning and personal care products. APs have been detected in the tissues of fish from the Great Lakes, and one AP (nonylphenol) causes vitellogenin gene expression in trout hepatocytes. Numerous APs and ethoxylates were recommended by the ITC because data are needed on: (1) chemical composition, (2) environmental fate of parent chemicals and impurities, and (3) health and ecological effects (including toxicokinetics and endocrine-modulating effects). In response to the ITC's recommendations, two activities have ensued. First, the EPA promulgated rules requiring manufacturers, importers and processors of APs and ethoxylates to submit production and exposure reports, and unpublished health and safety studies, for review. Second, the Alkylphenols and Ethoxylates Panel of Chemical Manufacturers Association (CMA) and the ITC formed a Dialogue Group to discuss the data needs. Data needs and activities initiated by the Dialogue Group will be presented.

  1. Chemical warfare

    PubMed Central

    Samuels, Richard Ian; Mattoso, Thalles Cardoso; Moreira, Denise D.O.

    2013-01-01

    Leaf-cutting ants are well known for their highly complex social organization, which provides them with a strong defense against parasites invading their colonies. Besides this attribute, these insects have morphological, physiological and structural characteristics further reinforcing the defense of their colonies. With the discovery of symbiotic bacteria present on the integument of leaf-cutting ants, a new line of defense was proposed and considered to be specific for the control of a specialized fungal parasite of the ants’ fungus gardens (Escovopsis). However, recent studies have questioned the specificity of the integumental bacteria, as they were also found to inhibit a range of fungi, including entomopathogens. The microbiota associated with the leaf-cutting ant gardens has also been proposed as another level of chemical defense, protecting the garden from parasite invasion. Here we review the chemical defense weaponry deployed by leaf-cutting ants against parasites of their fungus gardens and of the ants themselves. PMID:23795235

  2. Guidance on the management of polychlorinated biphenyls (PCBs)

    SciTech Connect

    Not Available

    1993-11-01

    Polychlorinated biphenyls (PCBs) are a class of synthetic organic chemicals including 209 known isomers, each with from 1 to 10 chlorine atoms on a biphenyl ring. PCBs have a number of desirable properties for industrial applications including thermal stability, flame retardance, and low vapor pressure. Because of these properties, PCBs were widely used as dielectric fluid in electrical equipment such as utility transformers and capacitors. PCBs were also extensively used in hydraulic fluid and heat transfer fluid, in gaskets, as additives in cutting oils and lubricant, and in a variety of other uses. The Toxic Substances Control Act (TSCA) banned the manufacture of PCBs after 1978 in response to emerging information about the adverse health effects of PCBs and their persistence in the environment. In addition, TSCA directed the Administrator of the Environmental Protection Agency (EPA) to prescribe methods for disposal of PCBS, require marking of PCBs with warning labels, and control their use. The TSCA regulations allow continued use of PCBs provided that the use is totally enclosed and does not pose a risk to human health or the environment. However, at the end of their useful life, all PCB materials must be disposed of according to the TSCA regulations. This guidance document uses graphics and flow charts where possible to present the TSCA regulations according to management activities such as use, storage, disposal, and spill cleanup. The document is designed to be read on an as-needed basis; that is, each chapter can stand alone or may be read in combination with others to help the reader determine the regulations relevant to his or her individual situation and needs. Every attempt has been made to include the requirements of other statutes and regulations that apply to PCB materials and provide references for the reader to consult for additional information.

  3. 78 FR 16698 - Chemical Facility Anti-Terrorism Standards (CFATS) Chemical-Terrorism Vulnerability Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... Information (CVI) for an additional 30 days for public comments. \\1\\ See 77 FR 74685. The 60-day Federal... statutory mandate at 72 FR 17688. Section 550 of the Homeland Security Appropriations Act of 2007 requires a... SECURITY Chemical Facility Anti-Terrorism Standards (CFATS) Chemical- Terrorism Vulnerability...

  4. [Euthanasia and medical act].

    PubMed

    2011-05-01

    Right to life -as the prohibition of intentionally and arbitrarily taking life, even with authorization of the concerned one- is an internationally recognized right. In many countries, debate regarding euthanasia is more centered in its convenience, social acceptability and how it is regulated, than in its substantial legitimacy. Some argue that euthanasia should be included as part of clinical practice of health professionals, grounded on individual's autonomy claims-everyone having the liberty to choose how to live and how to die. Against this, others sustain that life has a higher value than autonomy, exercising autonomy without respecting the right to life would become a serious moral and social problem. Likewise, euthanasia supporters some-times claim a 'right to live with dignity', which must be understood as a personal obligation, referred more to the ethical than to the strictly legal sphere. In countries where it is already legalized, euthanasia practice has extended to cases where it is not the patient who requests this but the family or some healthcare professional, or even the legal system-when they think that the patient is living in a condition which is not worthy to live. Generalization of euthanasia possibly will end in affecting those who need more care, such as elder, chronically ill or dying people, damaging severely personal basic rights. Nature, purpose and tradition of medicine rule out the practice of euthanasia, which ought not be considered a medical act or legitimately compulsory for physicians. Today's medicine counts with effective treatments for pain and suffering, such as palliative care, including sedative therapy, which best preserves persons dignity and keeps safe the ethos of the medical profession. PMID:22051717

  5. 40 CFR 712.30 - Chemical lists and reporting periods.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Chemical lists and reporting periods. 712.30 Section 712.30 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT CHEMICAL INFORMATION RULES Manufacturers Reporting-Preliminary Assessment Information § 712.30 Chemical lists and...

  6. 40 CFR 712.30 - Chemical lists and reporting periods.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Chemical lists and reporting periods... SUBSTANCES CONTROL ACT CHEMICAL INFORMATION RULES Manufacturers Reporting-Preliminary Assessment Information § 712.30 Chemical lists and reporting periods. (a)(1) Persons subject to this subpart B must submit...

  7. 40 CFR 712.30 - Chemical lists and reporting periods.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Chemical lists and reporting periods... SUBSTANCES CONTROL ACT CHEMICAL INFORMATION RULES Manufacturers Reporting-Preliminary Assessment Information § 712.30 Chemical lists and reporting periods. (a)(1) Persons subject to this subpart B must submit...

  8. 40 CFR 712.30 - Chemical lists and reporting periods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Chemical lists and reporting periods... SUBSTANCES CONTROL ACT CHEMICAL INFORMATION RULES Manufacturers Reporting-Preliminary Assessment Information § 712.30 Chemical lists and reporting periods. (a)(1) Persons subject to this subpart B must submit...

  9. 75 FR 37301 - Exempt Chemical Mixtures Containing Gamma-Butyrolactone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... ``Implementation of the Domestic Chemical Diversion Control Act of 1993 (DCDCA)'' (59 FR 51887, October 13, 1994; withdrawn at 59 FR 63738, December 9, 1994)) until it promulgates a final rule that identifies chemical... Notice of Proposed Rulemaking (73 FR 66815) which proposed the control of certain GBL chemical...

  10. 40 CFR 799.5085 - Chemical testing requirements for first group of high production volume chemicals (HPV1).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Chemical testing requirements for first group of high production volume chemicals (HPV1). 799.5085 Section 799.5085 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND...

  11. 40 CFR 799.5087 - Chemical testing requirements for second group of high production volume chemicals (HPV2).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Chemical testing requirements for second group of high production volume chemicals (HPV2). 799.5087 Section 799.5087 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND...

  12. 40 CFR 799.5089 - Chemical testing requirements for third group of high production volume chemicals (HPV3).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Chemical testing requirements for third group of high production volume chemicals (HPV3). 799.5089 Section 799.5089 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF SPECIFIC CHEMICAL SUBSTANCE AND...

  13. Chemical lasers

    NASA Astrophysics Data System (ADS)

    Khariton, Y.

    1984-08-01

    The application and the advances of quantum electronics, specifically, of optical quantum generators lasers is reviewed. Materials are cut, their surfaces are machined, chemical transformations of substances are carried out, surgical operations are performed, data are transmitted, three dimensional images are produced and the content of microimpurities, in the atmosphere, are analyzed by use of a beam. Laser technology is used in conducting investigations in the most diverse fields of the natural and technical sciences from controlled thermonuclear fusion to genetics. Many demands are placed on lasers as sources of light energy. The importance of low weight, compactness of the optical generator and the efficiency of energy conversion processes is emphasized.

  14. 7 CFR 63.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) NATIONAL SHEEP INDUSTRY IMPROVEMENT CENTER... Development Act, 7 U.S.C. 2008j, as amended by section 11009 of the Food, Conservation, and Energy Act of...

  15. 7 CFR 63.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) NATIONAL SHEEP INDUSTRY IMPROVEMENT CENTER... Development Act, 7 U.S.C. 2008j, as amended by section 11009 of the Food, Conservation, and Energy Act of...

  16. 7 CFR 63.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) NATIONAL SHEEP INDUSTRY IMPROVEMENT CENTER... Development Act, 7 U.S.C. 2008j, as amended by section 11009 of the Food, Conservation, and Energy Act of...

  17. 7 CFR 63.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) NATIONAL SHEEP INDUSTRY IMPROVEMENT CENTER... Development Act, 7 U.S.C. 2008j, as amended by section 11009 of the Food, Conservation, and Energy Act of...

  18. The Privacy Act of 1974.

    ERIC Educational Resources Information Center

    O'Reilly, James T.

    This report describes the possible impact of the comprehensive Privacy Act of 1974, which went into effect on 27 September 1975. Specifically, the implications of the act for limitation of disclosure, federal information collection, individual access, private suits; criminal provisions; and exceptions to the provisions of the law are detailed. In…

  19. Nurse Reinvestment Act. Public Law.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC.

    This document contains the text of the Nurse Reinvestment Act, which amends the Public Health Service Act to address the increasing shortage of registered nurses by instituting a series of policies to improve nurse recruitment and nurse retention. Title I details two initiatives to boost recruitment of nurses. The first initiative includes the…

  20. 76 FR 59073 - Privacy Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... From the Federal Register Online via the Government Publishing Office CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1901 Privacy Act AGENCY: Central Intelligence Agency. ACTION: Proposed rule. SUMMARY: Consistent with the Privacy Act (PA), the Central Intelligence Agency (CIA) has undertaken and completed...

  1. Biomass Program Recovery Act Factsheet

    SciTech Connect

    2010-03-01

    The Biomass Program has awarded about $718 million in American Recovery and Reinvestment Act (Recovery Act) funds. The projects the Program is supporting are intended to: Accelerate advanced biofuels research, development, and demonstration; Speed the deployment and commercialization of advanced biofuels and bioproducts; Further the U.S. bioindustry through market transformation and creating or saving a range of jobs.

  2. Education Leaders Applaud ATTAIN Act

    ERIC Educational Resources Information Center

    Curriculum Review, 2007

    2007-01-01

    This article talks about Achievement Through Technology and Innovation (ATTAIN) Act, a bill introduced by Senators Bingaman (D-NM), Burr (R-NC), and Murray (D-WA) and applauded by a coalition of education and industry groups. The proposed ATTAIN Act is similar to its companion in the House (HR 2449), and builds upon the Enhancing Education Through…

  3. Act of 13 March 1989.

    PubMed

    1989-01-01

    This document contains the text of a 1989 Act of Utah prohibiting surrogate parenthood agreements of any type. Surrogate mothers are the legal mothers of their children, and their husbands are the legal fathers. This Act has no impact on adoption laws. PMID:12344464

  4. Implementing the Amended FOI Act.

    ERIC Educational Resources Information Center

    McClain, Wallis

    The Freedom of Information Act amendments, which became effective in February 1975, have so far yielded mixed results. This report provides an account of how different federal agencies are implementing this amended statute. Among the topics discussed are modifications of the original 1966 Freedom of Information Act, which were made in the attempt…

  5. Acting to let someone die.

    PubMed

    McGee, Andrew

    2015-02-01

    This paper examines the recent prominent view in medical ethics that withdrawing life-sustaining treatment (LST) is an act of killing. I trace this view to the rejection of the traditional claim that withdrawing LST is an omission rather than an act. Although that traditional claim is not as problematic as this recent prominent view suggests, my main claim is that even if we accepted that withdrawing LST should be classified as an act rather than as an omission, it could still be classified as letting die rather than killing. Even though omissions are contrasted with acts, letting die need not be, for one can let die by means of acts. The remainder of the paper is devoted to establishing this claim and addresses certain objections to it. PMID:24320715

  6. Hazardous chemical tracking system (HAZ-TRAC)

    SciTech Connect

    Bramlette, J D; Ewart, S M; Jones, C E

    1990-07-01

    Westinghouse Idaho Nuclear Company, Inc. (WINCO) developed and implemented a computerized hazardous chemical tracking system, referred to as Haz-Trac, for use at the Idaho Chemical Processing Plant (ICPP). Haz-Trac is designed to provide a means to improve the accuracy and reliability of chemical information, which enhances the overall quality and safety of ICPP operations. The system tracks all chemicals and chemical components from the time they enter the ICPP until the chemical changes form, is used, or becomes a waste. The system runs on a Hewlett-Packard (HP) 3000 Series 70 computer. The system is written in COBOL and uses VIEW/3000, TurboIMAGE/DBMS 3000, OMNIDEX, and SPEEDWARE. The HP 3000 may be accessed throughout the ICPP, and from remote locations, using data communication lines. Haz-Trac went into production in October, 1989. Currently, over 1910 chemicals and chemical components are tracked on the system. More than 2500 personnel hours were saved during the first six months of operation. Cost savings have been realized by reducing the time needed to collect and compile reporting information, identifying and disposing of unneeded chemicals, and eliminating duplicate inventories. Haz-Trac maintains information required by the Superfund Amendment Reauthorization Act (SARA), the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) and the Occupational Safety and Health Administration (OSHA).

  7. 76 FR 14439 - No FEAR Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... TRANSPARENCY BOARD No FEAR Act Notice AGENCY: Recovery Accountability and Transparency Board. ACTION: Notice... and Retaliation Act (No FEAR Act or Act), as implemented by Office of Personnel Management (OPM... No FEAR Act. See Public Law 107-174, codified at 5 U.S.C. 2301 note. One purpose of the Act is...

  8. Assessment & Commitment Tracking System (ACTS)

    2004-12-20

    The ACTS computer code provides a centralized tool for planning and scheduling assessments, tracking and managing actions associated with assessments or that result from an event or condition, and "mining" data for reporting and analyzing information for improving performance. The ACTS application is designed to work with the MS SQL database management system. All database interfaces are written in SQL. The following software is used to develop and support the ACTS application: Cold Fusion HTMLmore » JavaScript Quest TOAD Microsoft Visual Source Safe (VSS) HTML Mailer for sending email Microsoft SQL Microsoft Internet Information Server« less

  9. Assessment & Commitment Tracking System (ACTS)

    SciTech Connect

    Bryant, Robert A.; Childs, Teresa A.; Miller, Michael A.; Sellars, Kevin J.

    2004-12-20

    The ACTS computer code provides a centralized tool for planning and scheduling assessments, tracking and managing actions associated with assessments or that result from an event or condition, and "mining" data for reporting and analyzing information for improving performance. The ACTS application is designed to work with the MS SQL database management system. All database interfaces are written in SQL. The following software is used to develop and support the ACTS application: Cold Fusion HTML JavaScript Quest TOAD Microsoft Visual Source Safe (VSS) HTML Mailer for sending email Microsoft SQL Microsoft Internet Information Server

  10. ACTS and OLYMPUS propagation experiments

    NASA Technical Reports Server (NTRS)

    Bostian, Charles W.; Baker, Kenneth R.

    1988-01-01

    The OLYMPUS and ACTS satellites both provide opportunities for 10 to 30 GHz propagation measurements. The spacecraft are sufficiently alike that OLYMPUS can be used to test some prototype ACTS equipment and experiments. Data are particularly needed on short term signal behavior and in support of uplink power control and adaptive forward error correction (FEC) techniques. The Virginia Tech Satellite Communications Group has proposed a set of OLYMPUS experiments including attenuation and fade rate measurements, data communications, uplink power control, rain scatter interference, and small-scale site diversity operation. A digital signal processing receiver for the OLYMPUS and ACTS beacon signals is being developed.

  11. Savannah River Site sample and analysis plan for Clemson Technical Center waste

    SciTech Connect

    Hagstrom, T.

    1998-04-01

    The purpose of this sampling and analysis plan is to determine the chemical, physical and radiological properties of the SRS radioactive Polychlorinated Biphenyl (PCB) liquid waste stream, to verify that it conforms to Waste Acceptance Criteria of the Department of Energy (DOE) East Tennessee Technology Park (ETTP) Toxic Substance Control Act (TSCA) Incineration Facility. Waste being sent to the ETTP TSCA Incinerator for treatment must be sufficiently characterized to ensure that the waste stream meets the waste acceptance criteria to ensure proper handling, classification, and processing of incoming waste to meet the Waste Storage and Treatment Facility`s Operating Permits. This sampling and analysis plan is limited to WSRC container(s) of homogeneous or multiphasic radioactive PCB contaminated liquids generated in association with a treatability study at Clemson Technical Center (CTC) and currently stored at the WSRC Solid Waste Division Mixed Waste Storage Facility (MWSF).

  12. Model Occupational Therapy Practice Act

    ERIC Educational Resources Information Center

    American Journal of Occupational Therapy, 1975

    1975-01-01

    The Model Occupational Therapy Practice Act has been assembled by the Government Affairs Department, American Occupational Therapy Association, for use as a guide for affiliate organizations concerned with developing legislation to regulate the practice of occupational therapy. (Author/JA)

  13. 78 FR 73466 - Privacy Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... or qualifications for Federal civilian employment, military service, Federal contracts or access to... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION 22 CFR Part 707 Privacy Act AGENCY: Overseas Private Investment Corporation. ACTION: Notice...

  14. Prelinguistic Vocalizations Distinguish Pointing Acts

    ERIC Educational Resources Information Center

    Grunloh, Thomas; Liszkowski, Ulf

    2015-01-01

    The current study investigated whether point-accompanying characteristics, like vocalizations and hand shape, differentiate infants' underlying motives of prelinguistic pointing. We elicited imperative (requestive) and declarative (expressive and informative) pointing acts in experimentally controlled situations, and analyzed accompanying…

  15. Monitoring EERE's Recovery Act Portfolio

    SciTech Connect

    2011-01-01

    Performance monitoring of Recovery Act projects within EERE has been an ongoing effort. Project recipients have been reporting technical and financial progress to project officers on a quarterly basis.

  16. 78 FR 23624 - Determination and Certification Under the Foreign Assistance Act Relating to the Largest...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Determination and Certification Under the Foreign Assistance Act Relating to the Largest Exporting and Importing Countries of Certain Precursor Chemicals Pursuant to Section 490(b)(1)(A) of the Foreign Assistance Act...

  17. 75 FR 18239 - Notice of Proposed Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... of Proposed Consent Decree Under the Clean Air Act Notice is hereby given that on March 31, 2010, two proposed Consent Decrees were lodged. United States et al. v. Shell Chemical LP, Civil Action No. 4:10-cv... District Court for the District of Puerto Rico. The Consent Decrees in these Clean Air Act...

  18. 78 FR 7777 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... seq.), as prescribed in 5 CFR 1320.12. On May 7, 2012 (77 FR 26750), EPA sought comments on this ICR...; Notification of Chemical Exports--TSCA Section 12(b) AGENCY: Environmental Protection Agency (EPA). ACTION... of Chemical Exports--TSCA Section 12(b)'' and identified as EPA ICR No. 0795.14 and OMB Control...

  19. 75 FR 29 - Privacy Act, Government in the Sunshine Act, Freedom of Information Act (“FOIA”), and Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... the Sunshine Act, Freedom of Information Act (``FOIA''), and Federal Election Campaign Act (``FECA... of Information Act of 1966, as amended, 5 U.S.C. 552, and the Federal Election Campaign Act (``FECA... requirements. 11 CFR Part 104 Campaign funds, Political committees and parties, Reporting and...

  20. Clean Air Act: Senate mulls revision bill

    SciTech Connect

    Fairley, P.

    1995-12-13

    Senator Lauch Faircloth (R., NC) has circulated a draft summary of possible revisions of the Clean Air Act (CAA). Chemical industry sources say the proposal would provide some regulatory relief but fear that supporting Faircloth could jeopardize their relationship with EPA. Faircloth`s proposal addresses various controversial aspect of CAA`s Title V permit program including the monitoring and permit modification provisions. The proposal would also define a facility`s {open_quotes}potential to emit,{close_quotes} upon which Title V permits are based. In the past year EPA has substantially revised its Title V program to address complaints from industry, the states, and Congress that the monitoring and modification provisions were too burdensome.

  1. Shedding Light on Synergistic Chemical Genetic Connections with Machine Learning.

    PubMed

    Ekins, Sean; Siqueira-Neto, Jair Lage

    2015-12-23

    Machine learning can be used to predict compounds acting synergistically, and this could greatly expand the universe of available potential treatments for diseases that are currently hidden in the dark chemical matter. PMID:27136350

  2. Interpreting Metabolomics Data to Mode of Action of Chemicals

    EPA Science Inventory

    Metabolomics approach utilizes high-throughput identification, quantification, and characterization of low molecular weight endogenous metabolites from numerous metabolic pathways. Exposure to environmental chemicals, which act through multiple mechanisms, cause perturbation of...

  3. 75 FR 36067 - Agency Information Collection Activities; Proposed Collection; Comment Request; Chemical-Specific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... provide it in the body of your comment. If you send an e- mail comment directly to EPA without going... comment, EPA recommends that you include your name and other contact information in the body of your... information under TSCA section 8(a) to evaluate the potential for adverse human health and...

  4. 78 FR 4806 - Proposed Significant New Use Rule on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... issue of September 21, 2012 (77 FR 58666) (FRL-9357-2), EPA issued direct final SNURs on these four... Federal Register issue of April 24, 1990 (55 FR 17376), EPA has decided that the intent of TSCA section 5... 12866, entitled ``Regulatory Planning and Review'' (58 FR 51735, October 4, 1993). B....

  5. 77 FR 20296 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... direct final SNUR published in the Federal Register issue of April 24, 1990 (55 FR 17376) (April 24, 1990... and P-10-487) that are subject to ``risk-based'' consent orders under TSCA section 5(e)(1)(A)(ii)(I... substances are promulgated pursuant to Sec. 721.160, and are based on and consistent with the provisions...

  6. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality...

  7. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality...

  8. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality...

  9. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality...

  10. 7 CFR 33.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of American-grown apples in foreign markets, to prevent deception or misrepresentation as to the quality...

  11. Amendments to the asbestos in schools provisions of TSCA: report to accompany H. R. 3893. Introduced in the House of Representatives, One Hundredth Congress, Second Session, June 27, 1988

    SciTech Connect

    Not Available

    1988-01-01

    H.R. 3893 amends the Asbestos Hazard Emergency Response Act (AHERA), Title II of the Toxic Substances Control Act, to allow local education agencies to obtain a deferral to May 9, 1989, of the October 12, 1988, statutory deadline for submission of asbestos management plans to State Governors. To obtain the deferral, a local education agency must submit a request for one or all of the school buildings in its district to the State Governor no later than October 12, 1988. The request will be deemed approved upon a finding by the Governor that the deferred request is complete. H.R. 3893 also codifies existing regulations which protect employees of school buildings from being exposed to asbestos-containing material without proper training or inspections to determine whether the building material contains asbestos. The Committee on Energy and Commerce reports favorably on H.R. 3893, as amended, and recommends its passage.

  12. 40 CFR 761.253 - Chemical analysis.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... analysis. (a) Extract PCBs from the standard wipe sample collection medium and clean-up the extracted...

  13. 40 CFR 761.253 - Chemical analysis.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... analysis. (a) Extract PCBs from the standard wipe sample collection medium and clean-up the extracted...

  14. 40 CFR 761.253 - Chemical analysis.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... Sample Sites, Collecting Surface Samples, and Analyzing Standard PCB Wipe Samples § 761.253...

  15. 40 CFR 761.253 - Chemical analysis.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... Sample Sites, Collecting Surface Samples, and Analyzing Standard PCB Wipe Samples § 761.253...

  16. 40 CFR 761.253 - Chemical analysis.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... Sample Sites, Collecting Surface Samples, and Analyzing Standard PCB Wipe Samples § 761.253...

  17. EFFECT OF CHEMICAL CARRIERS ON AVIAN LC(50) TOXICITY TESTS

    EPA Science Inventory

    The subacute dietary (LC50) toxicity of a pesticide as prescribed by the Federal Insecticide Fungicide and Rodenticide Act and of toxic substances as defined by the Toxic Substances Control Act is a routine data point for many chemicals. The methods under which the LC50 data are ...

  18. Adsorption of direct-acting and indirect-acting mutagens by various dietary fibers.

    PubMed

    Karakaya, S; Kavas, A

    1999-09-01

    The protective effect of dietary fiber on human cancer has received great attention during the last decades. Because dietary fiber constitutes a large group of complex polysaccharides with various solubilities, degrees of lignification, chemical compositions and structural arrangements, several mechanisms for their effects have been proposed. In this study, in vitro binding capacities of various dietary fibers (potato fiber and glucomannan) and dietary fiber constituents (pectic acid and cellulose) against indirect mutagen 2-amino-3-methyl-3H-imidazo (4,5-f) quinoline (IQ) and direct-acting mutagen sodium azide were investigated. Direct-acting mutagen sodium azide was not adsorbed to the dietary fiber and dietary fiber constituents of 0 degree C, pH 4.5 and 37 degrees C, pH 7.0. However, indirect-acting mutagen 2-amino-3-methyl-3H-imidazo (4,5-f) quinoline (IQ) were sorbed by them in variable ratios at 0 degree C, pH 4.5 and 37 degrees C, pH 7.0. The differences between the in vitro binding capacities of the samples at two experimental conditions were found to be statiscially significant (P < 0.01). IQ was not released from the dietary fibers and constituents in distilled water. PMID:10719562

  19. Long-acting muscarinic antagonists.

    PubMed

    Melani, Andrea S

    2015-01-01

    Chronic obstructive pulmonary disease (COPD) is a major cause of death and disability worldwide. Inhaled bronchodilators are the mainstay of COPD pharmacological treatment. Long-acting muscarinic antagonists (LAMAs) are a major class of inhaled bronchodilators. Some LAMA/device systems with different characteristics and dosing schedules are currently approved for maintenance therapy of COPD and a range of other products are being developed. They improve lung function and patient-reported outcomes and reduce acute bronchial exacerbations with good safety. LAMAs are used either alone or associated with long-acting β₂-agonists, eventually in fixed dose combinations. Long-acting β₂-agonist/LAMA combinations assure additional benefits over the individual components alone. The reader will obtain a view of the safety and efficacy of the different LAMA/device systems in COPD patients. PMID:26109098

  20. 7 CFR 1150.101 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.101 Act. Act means Title I, Subtitle B, of the Dairy and Tobacco Adjustment Act of...

  1. 7 CFR 1150.101 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.101 Act. Act means Title I, Subtitle B, of the Dairy and Tobacco Adjustment Act of...

  2. 7 CFR 1150.101 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.101 Act. Act means Title I, Subtitle B, of the Dairy and Tobacco Adjustment Act of...

  3. 7 CFR 1150.101 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.101 Act. Act means Title I, Subtitle B, of the Dairy and Tobacco Adjustment Act of...

  4. [Suicide, a philosophical act or an act of depression?].

    PubMed

    Heslon, Christian

    2016-01-01

    Suicide is more frequent in people aged over 75 than in the rest of the population. Is it the fact of feeling too old or of being alone? Is the person fully lucid? The question of responsibility is raised, as is the meaning of the act: the ultimate living gesture or capitulation in the face of death? PMID:27173624

  5. Get Your ACT Together: A Resource Guide for ACT Preparation.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Education, Oklahoma City.

    This guide is designed as a resource for (1) Oklahoma teachers, counselors, and parents, to help them help their students prepare for the ACT assessment; and (2) students, to help dispel some common myths and misunderstandings as they prepare for the test. Section A, for administrators, teachers, counselors, Indian program staffs, and…

  6. Advanced Communications Technology Satellite (ACTS)

    NASA Astrophysics Data System (ADS)

    Gedney, Richard T.; Schertler, Ronald J.

    1989-06-01

    The NASA Advanced Communications Technology Satellite (ACTS) was conceived to help maintain U.S. leadership in the world's communications-satellite market. This experimental satellite is expected to be launched by NASA in 1992 and to furnish the technology necessary for establishing very small aperture terminal digital networks which provide on-demand full-mesh connectivity, and 1.544-MBPS services with only a single hop. Utilizing on-board switching and processing, each individual voice or data circuit can be separately routed to any location in the network. This paper provides an overview of the ACTS and discusses the value of the technology for future communications systems.

  7. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Gedney, Richard T.; Schertler, Ronald J.

    1989-01-01

    The NASA Advanced Communications Technology Satellite (ACTS) was conceived to help maintain U.S. leadership in the world's communications-satellite market. This experimental satellite is expected to be launched by NASA in 1992 and to furnish the technology necessary for establishing very small aperture terminal digital networks which provide on-demand full-mesh connectivity, and 1.544-MBPS services with only a single hop. Utilizing on-board switching and processing, each individual voice or data circuit can be separately routed to any location in the network. This paper provides an overview of the ACTS and discusses the value of the technology for future communications systems.

  8. Self-acting shaft seals

    NASA Technical Reports Server (NTRS)

    Ludwig, L. P.

    1978-01-01

    Self-acting seals are described in detail. The mathematical models for obtaining a seal force balance and the equilibrium operating film thickness are outlined. Particular attention is given to primary ring response (seal vibration) to rotating seat face runout. This response analysis reveals three different vibration models with secondary seal friction being an important parameter. Leakage flow inlet pressure drop and affects of axisymmetric sealing face deformations are discussed. Experimental data on self-acting face seals operating under simulated gas turbine conditions are given. Also a spiral groove seal design operated to 244 m/sec (800 ft/sec) is described.

  9. 40 CFR 745.87 - Enforcement and inspections.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Residential Property... permit entry or inspection as required by 40 CFR 745.87 and TSCA section 11 (15 U.S.C. 2610) is a... criminal sanctions pursuant to TSCA section 16 (15 U.S.C. 2615) for each violation. (e) Lead-based paint...

  10. 40 CFR 745.87 - Enforcement and inspections.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Residential Property... permit entry or inspection as required by 40 CFR 745.87 and TSCA section 11 (15 U.S.C. 2610) is a... criminal sanctions pursuant to TSCA section 16 (15 U.S.C. 2615) for each violation. (e) Lead-based paint...

  11. 40 CFR 745.87 - Enforcement and inspections.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Residential Property... permit entry or inspection as required by 40 CFR 745.87 and TSCA section 11 (15 U.S.C. 2610) is a... criminal sanctions pursuant to TSCA section 16 (15 U.S.C. 2615) for each violation. (e) Lead-based paint...

  12. 40 CFR 745.87 - Enforcement and inspections.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Residential Property... permit entry or inspection as required by 40 CFR 745.87 and TSCA section 11 (15 U.S.C. 2610) is a... criminal sanctions pursuant to TSCA section 16 (15 U.S.C. 2615) for each violation. (e) Lead-based paint...

  13. 75 FR 63170 - Access to Confidential Business Information by Avanti Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... Substances Control Act (TSCA). Some of the information may be claimed or determined to be Confidential... available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material...; e-mail address: moseley.pamela@epa.gov . For general information contact: The TSCA-Hotline,...

  14. 76 FR 27044 - Lead-Based Paint Renovation, Repair and Painting, and Pre-Renovation Education Activities in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... Reduction. In the Federal Register dated April 22, 2008, (73 FR 21692), EPA promulgated final TSCA section... dust sampling technicians. In the Federal Register of June 1, 1998, (63 FR 29908), EPA promulgated... authorized under section 404(a) of the Toxic Substances Control Act (TSCA), 15 U.S.C. 2684(a), to...

  15. 7 CFR 1220.600 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the...

  16. 7 CFR 1220.600 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the...

  17. 7 CFR 1220.600 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the...

  18. 7 CFR 1220.600 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the...

  19. 7 CFR 1220.600 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the...

  20. 7 CFR 1207.302 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  1. 7 CFR 1207.302 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  2. 7 CFR 1207.302 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  3. 7 CFR 1207.302 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  4. 7 CFR 1207.302 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  5. 7 CFR 1218.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means...

  6. 7 CFR 1218.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means...

  7. 7 CFR 1218.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means...

  8. 7 CFR 1218.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means...

  9. 7 CFR 1218.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means...

  10. 7 CFR 1216.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means...

  11. 7 CFR 1216.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means...

  12. 7 CFR 1216.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means...

  13. 7 CFR 1216.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means...

  14. 7 CFR 1216.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means...

  15. 7 CFR 1221.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means...

  16. 7 CFR 1221.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means...

  17. 7 CFR 1221.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means...

  18. 7 CFR 1221.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means...

  19. 7 CFR 1206.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the...

  20. 7 CFR 1206.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the...

  1. 7 CFR 1206.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the...

  2. 7 CFR 1206.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the...

  3. 7 CFR 1206.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the...

  4. 7 CFR 1221.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SORGHUM PROMOTION, RESEARCH, AND INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means...

  5. Chemical Genetics in Dissecting Membrane Glycerolipid Functions.

    PubMed

    Chevalier, Florian; Carrera, Laura Cuyàs; Nussaume, Laurent; Maréchal, Eric

    2016-01-01

    Chemical genetics has emerged as a powerful approach to dissect biological processes, based on the utilization of small molecules disturbing the function of specific target proteins. By analogy with classical genetics, 'reverse chemical genetics' refers to the utilization of drugs acting on a known target, enabling its functional characterization at the levels of the cells, tissues and organisms. Likewise, 'direct chemical genetics' refers to the utilization of a drug of unknown mode of action, but triggering a phenotype of interest. In that case, one has to identify the target(s) possibly blocked (or possibly activated) by the small molecule. This chapter illustrates both approaches, like the analysis of the elongation of fatty acids, the biosynthesis of galactoglycerolipids or the catabolism of phosphoglycerolipids by reverse chemical genetics or the study of the membrane glycerolipid remodeling triggered upon phosphate starvation, by direct chemical genetics. PMID:27023235

  6. A procoagulant chemically sulfated mannan.

    PubMed

    Gracher, Ana Helena P; Santana, Aline G; Cipriani, Thales R; Iacomini, Marcello

    2016-01-20

    Disorders of hemostasis can produce innumerous problems. Polysaccharides have been studied both as anticoagulant and as procoagulant agents. A mannan with a main chain of α-(1 → 6)-linked-Manp units, branched at O-2 mainly by side-chains of 2-O-linked-α-Manp units was chemically sulfated, structurally characterized by NMR and GC-MS (methylation, desulfation and methylation with trideuterated iodomethane), and tested in vitro and in vivo on blood coagulation models. Chemical analyses indicate a high degree of substitution on the sulfated polysaccharide. This polymer acted as a procoagulant agent, increasing blood coagulation in normal and hemophilic plasma, activated platelet aggregation and also decreased ex vivo aPTT. Polymers such as the sulfated mannan could be a helpful source of hemostatic agents to prevent hemorrhagic states. PMID:26572344

  7. Chemical Ecology: Chemical Communication in Nature.

    ERIC Educational Resources Information Center

    Wood, William F.

    1983-01-01

    Substances that deliver chemical messages between same/different species are called semiochemicals. Surveyed are three types of semiochemicals (pheromones, allomones, and kairomones), types of organisms involved, and specific chemicals used to carry the various kinds of messages. (JN)

  8. Act To Promote Adult Education.

    ERIC Educational Resources Information Center

    1970

    An act of the German Lower Saxony Parliament to promote adult education is presented. It has 24 general provisions relating to the following: purpose of adult education, principle for promotion, conditions for promotions of establishments, independence of adult education, prerequisites and form of acknowledgement of entitlement to promotion,…

  9. 78 FR 46256 - Privacy Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... From the Federal Register Online via the Government Publishing Office FEDERAL ELECTION COMMISSION 11 CFR Part 1 Privacy Act CFR Correction In Title 11 of the Code of Federal Regulations, revised as of January 1, 2012, on page 5, in Sec. 1.2, the words ``95 and 96 of the Internal Revenue Code...

  10. The Indian Child Welfare Act.

    ERIC Educational Resources Information Center

    Steward, Katy Jo

    The Indian Child Welfare Act of 1978 (I.C.W.A.) is federal legislation which preempts state law whenever Indian children may be removed from their families. The I.C.W.A. permits Indian tribal courts to decide the future of Indian children, establishes minimum federal standards for removal of Indian children from their families, requires that…

  11. The Ontogenesis of Speech Acts

    ERIC Educational Resources Information Center

    Bruner, Jerome S.

    1975-01-01

    A speech act approach to the transition from pre-linguistic to linguistic communication is adopted in order to consider language in relation to behavior and to allow for an emphasis on the use, rather than the form, of language. A pilot study of mothers and infants is discussed. (Author/RM)

  12. ACT and General Cognitive Ability

    ERIC Educational Resources Information Center

    Koenig, Katherine A.; Frey, Meredith C.; Detterman, Douglas K.

    2008-01-01

    Research on the SAT has shown a substantial correlation with measures of "g" such as the Armed Services Vocational Aptitude Battery (ASVAB). Another widely administered test for college admission is the American College Test (ACT). Using the National Longitudinal Survey of Youth 1979, measures of "g" were derived from the ASVAB and correlated with…

  13. Clery Act: Road to Compliance

    ERIC Educational Resources Information Center

    McNeal, Laura R.

    2007-01-01

    The purpose of this study was to explore what factors served as impediments to institutional efforts to comply with Clery Act guidelines through the perceptions of campus law administrators. Statistical analyses were performed on data collected from an online survey, which was distributed to members of the International Association of Campus Law…

  14. Dual acting slit control mechanism

    NASA Technical Reports Server (NTRS)

    Struthoff, G. L. (Inventor)

    1980-01-01

    A dual acting control system for mass spectrometers is described, which permits adjustment of the collimating slit width and centering of the collimating slit while using only one vacuum penetration. Coaxial shafts, each with independent vacuum bellows are used to independently move the entire collimating assembly or to adjust the slit dimension through a parallelogram linkage.

  15. Implementing the Reading Excellence Act.

    ERIC Educational Resources Information Center

    Lacy, Laurie; Dole, Janice; Donaldson, Becky; Donaldson, Brady

    This slide presentation outlines one state's (Utah) version of implementation of a model for literacy learning under the Reading Excellence Act (REA). According to the presentation, the model is called "The Utah Reads K-3 Literacy Model." The presentation is divided into the following sections: Utah's Vision: What We've Learned So Far; One…

  16. The Federal Employees' Compensation Act.

    ERIC Educational Resources Information Center

    Nordlund, Willis J.

    1991-01-01

    The 1916 Federal Employees' Compensation Act is still the focal point around which the federal workers compensation program works today. The program has gone through many changes on its way to becoming a modern means of compensating workers for job-related injury, disease, and death. (Author)

  17. Acting White: A Critical Review

    ERIC Educational Resources Information Center

    Sohn, Kitae

    2011-01-01

    The hypothesis of acting White has been heatedly debated and influential over the last 20 years or so in explaining the Black-White test score gap. Recently, economists have joined the debate and started providing new theoretical and empirical analyses of the phenomenon. This paper critically reviews the arguments that have been advanced to…

  18. Toxic chemicals and toxic laws

    SciTech Connect

    Koshland, D.E. Jr.

    1991-08-30

    Recently there was consternation when it was discovered that a program intended to help minorities and the underprivileged in Detroit might have to be canceled. The reason was that some of the land on which new buildings were built was thought to contain toxic chemicals and therefore fell under the provisions of the Comprehensive Environmental Response, Compensation, and Liability Act (or Superfund). This collision of two valuable programs illustrates how a program originally heralded to carry out a worthwhile goal can become flawed. Since 1980, when the Superfund Act was passed by an overwhelming majority in Congress, only 34 of 1,245 identified priority sites have been cleaned up while approximately 40% of the money has been spent in trial litigation and administrative oversight. Critics, many of them within the EPA, point out that if the chemical danger level had been scientifically determined, approximately 90% of the truly important sites could have been cleaned up by now and the money wisely spent. However, the program was designed so that Congress initially did not have to raise much money or raise taxes and instead could argue that the program would not cost the taxpayer anything because it soaked the corporations. What needs to be done First, priority decisions should be taken out of the hands of nonscientists and lawyers and placed in those of scientists who are knowledgeable about toxic agents, who can identify effective targets objectively and who can establish workable priorities for removal of toxic waste. Second, a significant fraction of the money should be dedicated to research and to new programs that are more cost-effective. The purpose is to get chemical manufacturers thinking about reducing pollutants and the cost of cleanup when they plan to manufacture a chemical.

  19. The Chemical Engineer in the Chemical Industry.

    ERIC Educational Resources Information Center

    Zabicky, Jacob

    1986-01-01

    Describes a course for third- or fourth-year chemical engineering students designed to acquaint them with the chemical industry. The course deals with productivity, characteristics of the chemical industry, sources of information, industrial intelligence, research and development, patent law, technology transfer, and quality control. (TW)

  20. 40 CFR 716.50 - Reporting physical and chemical properties.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Reporting physical and chemical properties. 716.50 Section 716.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.50 Reporting physical and chemical properties. Studies...

  1. 78 FR 16692 - Chemical Facility Anti-Terrorism Standards (CFATS)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ..., Chemical Facility Anti-Terrorism Standards (CFATS) for an additional 30 days. \\1\\ See 77 FR 74677. The 60... mandate at 72 FR 17688. Section 550 of the Homeland Security Appropriations Act of 2007 requires a risk... SECURITY Chemical Facility Anti-Terrorism Standards (CFATS) AGENCY: National Protection and...

  2. 21 CFR 1300.02 - Definitions relating to listed chemicals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... has been delegated authority under the Act by the Attorney General (28 CFR 0.100). At retail, with... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Definitions relating to listed chemicals. 1300.02....02 Definitions relating to listed chemicals. (a) Any term not defined in this part shall have...

  3. 40 CFR 716.50 - Reporting physical and chemical properties.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Reporting physical and chemical properties. 716.50 Section 716.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.50 Reporting physical and chemical properties. Studies...

  4. 40 CFR 716.50 - Reporting physical and chemical properties.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Reporting physical and chemical properties. 716.50 Section 716.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.50 Reporting physical and chemical properties. Studies...

  5. Chemical Stockpile Disposal Program

    SciTech Connect

    Krummel, J.R.; Policastro, A.J.; Olshansky, S.J.; McGinnis, L.D.

    1990-10-01

    As part of the Chemical Stockpile Disposal Program mandated by Public Law 99--145 (Department of Defense Authorization Act), an independent review is presented of the US Army Phase I environmental report for the disposal program at the Umatilla Depot Activity (UMDA) in Hermiston, Oregon. The Phase I report addressed new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). Those concerns were addressed by examining site-specific data for the Umatilla Depot Activity and by recommending the scope and content of a more detailed site-specific study. This independent review evaluates whether the new site-specific data presented in the Phase I report would alter the decision in favor of on-site disposal that was reached in the FPEIS, and whether the recommendations for the scope and content of the site-specific study are adequate. Based on the methods and assumptions presented in the FPEIS, the inclusion of more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at UMDA). It is recommended that alternative assumptions about meteorological conditions be considered and that site-specific data on water, ecological, socioeconomic, and cultural resources; seismicity; and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process. 7 refs., 1 fig.

  6. Chemical Stockpile Disposal Program

    SciTech Connect

    Krummel, J.R.; Policastro, A.J.; Olshansky, S.J.; McGinnis, L.D.

    1990-10-01

    As part of the Chemical Stockpile Disposal Program mandated by Public Law 99--145 (Department of Defense Authorization Act), an independent review is presented of the US Army Phase I environmental report for the disposal program at the Pine Bluff Arsenal (PBA) in Arkansas. The Phase I report addressed new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). Those concerns were addressed by examining site-specific data for the PBA and by recommending the scope and content of a more detailed site- specific study. This dependent review evaluates whether the new site-specific data presented in the Phase I report would alter the decision in favor of on-site disposal that was reached in the FPEIS, and whether the recommendations for the scope and content of the site-specific study are adequate. Based on the methods and assumptions presented in the FPEIS, the inclusion of more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at PBA). It is recommended that alternative assumptions about meteorological conditions be considered and that site-specific data on water, ecological, socioeconomic, and cultural resources, and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process. 13 refs., 1 fig.

  7. Microfluidic chemical reaction circuits

    DOEpatents

    Lee, Chung-cheng; Sui, Guodong; Elizarov, Arkadij; Kolb, Hartmuth C.; Huang, Jiang; Heath, James R.; Phelps, Michael E.; Quake, Stephen R.; Tseng, Hsian-rong; Wyatt, Paul; Daridon, Antoine

    2012-06-26

    New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.

  8. CHEMICAL SAFETY ALERTS-

    EPA Science Inventory

    Chemical Safety Alerts are short publications which explain specific hazards that have become evident through chemical accident investigation efforts. EPA has produced over a dozen Alerts to date. This year's Alert: Managing Chemical Reactivity Hazards

  9. CHEMICALS IN PROGRESS BULLETIN

    EPA Science Inventory

    Chemicals in Progress Bulletin is a quarterly newsletter which highlights regulatory and program activities of the Office of Pollution Prevention and Toxics. Regular features and news items include the existing chemicals program, new chemicals program, pollution prevention activi...

  10. 40 CFR 799.5115 - Chemical testing requirements for certain chemicals of interest to the Occupational Safety and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false Chemical testing requirements for certain chemicals of interest to the Occupational Safety and Health Administration. 799.5115 Section 799.5115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) IDENTIFICATION OF...

  11. Chemical Management System

    1998-10-30

    CMS provides an inventory of all chemicals on order or being held in the laboratory, to provide a specific location for all chemical containers, to ensure that health and safety regulatory codes are being upheld, and to provide PNNL staff with hazardous chemical information to better manage their inventories. CMS is comprised of five major modules: 1) chemical purchasing, 2) chemical inventory, 3) chemical names, properties, and hazard groups, 4) reporting, and 5) system administration.

  12. Nature's chemicals and synthetic chemicals: Comparative toxicology

    SciTech Connect

    Ames, B.N.; Profet, M.; Gold, L.S. )

    1990-10-01

    The toxicology of synthetic chemicals is compared to that of natural chemicals, which represent the vast bulk of the chemicals to which humans are exposed. It is argued that animals have a broad array of inducible general defenses to combat the changing array of toxic chemicals in plant food (nature's pesticides) and that these defenses are effective against both natural and synthetic toxins. Synthetic toxins such as dioxin are compared to natural chemicals, such as indole carbinol (in broccoli) and ethanol. Trade-offs between synthetic and natural pesticides are discussed. The finding that in high-dose tests, a high proportion of both natural and synthetic chemicals are carcinogens, mutagens, teratogens, and clastogens (30-50{percent} for each group) undermines current regulatory efforts to protect public health from synthetic chemicals based on these tests.

  13. Acting Out; Theoretical and Clinical Aspects.

    ERIC Educational Resources Information Center

    Abt, Lawrence Edwin, Ed.; Weissman, Stuart L.

    The beneficial and harmful effects of acting out are studied in a series of short essays by numerous authors. Included are four articles on the theoretical and dynamic considerations of acting out, along with five clinical manifestations of acting out involving suicide and criminality in adolescents and adults. Special forms of harmful acting out…

  14. 76 FR 13550 - Fur Products Labeling Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ...In December 2010, Congress passed the Truth in Fur Labeling Act (TFLA), which amends the Fur Products Labeling Act (Fur Act) by: (1) Eliminating the Commission's discretion to exempt fur products of relatively small quantity or value from disclosure requirements; and (2) providing that the Fur Act will not apply to certain fur products obtained through trapping or hunting and sold in face to......

  15. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums...

  16. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums...

  17. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums...

  18. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums...

  19. 7 CFR 35.1 - Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the United States in grapes and plums, to protect the reputation of American-grown grapes and plums...

  20. 10 CFR 430.61 - Prohibited acts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Prohibited acts. 430.61 Section 430.61 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CONSERVATION PROGRAM FOR CONSUMER PRODUCTS Certification and Enforcement § 430.61 Prohibited acts. (a) Each of the following is a prohibited act pursuant to section 332 of the Act: (1) Failure to permit access...

  1. 76 FR 25665 - No Fear Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... COMMISSION No Fear Act AGENCY: American Battle Monuments Commission. ACTION: Notice. SUMMARY: The American... notification obligation under the Notification and Federal Employees Antidiscrimination and Retaliation Act (No... Retaliation Act of 2002,'' which is now known as the No FEAR Act. See Public Law 107-174, codified at 5...

  2. Chemical Industry Corrosion Management

    SciTech Connect

    2003-02-01

    Improved Corrosion Management Could Provide Significant Cost and Energy Savings for the Chemical Industry. In the chemical industry, corrosion is often responsible for significant shutdown and maintenance costs.

  3. 40 CFR 711.35 - Electronic filing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... follow the appropriate links. (2) By phone or e-mail. Contact the EPA TSCA Hotline at (202) 554-1404 or... TSCA CHEMICAL DATA REPORTING REQUIREMENTS § 711.35 Electronic filing. (a) You must use e-CDRweb to...) Submissions must be sent electronically to EPA via CDX. (c) Access e-CDRweb and instructions, as follows:...

  4. Long-acting hormonal contraception.

    PubMed

    Benagiano, Giuseppe; Gabelnick, Henry; Brosens, Ivo

    2015-11-01

    Today, a new category of fertility-regulating agents has been created: long-acting, reversible hormonal contraceptives; they minimize compliance, while maximize effectiveness. They comprise subdermal implants and intrauterine devices. Other long-acting agents exist, such as Depo Provera and Noristerat. Use of Depo Provera and Noristerat carries great effectiveness, good clinical safety and usefulness in developing countries. They cause no significant increase in breast cancer risk, but they may carry an increased risk of HIV. Subcutaneous delivery systems have two common features: prolongation of effect is obtained by a drug reservoir and for most of their duration of action they provide a continuous, sustained release of the active hormone. Finally, the intrauterine system Mirena represents both a very effective contraceptive and a specific treatment for menorrhagia. PMID:26626534

  5. Advanced Communications Technology Satellite (ACTS)

    NASA Technical Reports Server (NTRS)

    Plecity, Mark S.; Nall, Mark E.

    1991-01-01

    The NASA Advanced Communications Technology Satellite (ACTS) provides high risk technologies having the potential to dramatically enhance the capabilities of the satellite communications industry. This experimental satellite, which will be launched by NASA in 1993, will furnish the technology necessary for providing a range of services. Utilizing the ACTS very-high-gain-hopping spot-beam antennas with on-board routing and processing, Very Small Aperture Terminal (VSAT) digital networks which provide on-demand, full-mesh-convectivity 1.544-MBPS services with only a single hop can be established. The high-gain spot-beam antenna at Ka-band permits wide area, flexible networks providing high data rate services between modest-size earth terminals.

  6. False memories for aggressive acts.

    PubMed

    Laney, Cara; Takarangi, Melanie K T

    2013-06-01

    Can people develop false memories for committing aggressive acts? How does this process compare to developing false memories for victimhood? In the current research we used a simple false feedback procedure to implant false memories for committing aggressive acts (causing a black eye or spreading malicious gossip) or for victimhood (receiving a black eye). We then compared these false memories to other subjects' true memories for equivalent events. False aggressive memories were all too easy to implant, particularly in the minds of individuals with a proclivity towards aggression. Once implanted, the false memories were indistinguishable from true memories for the same events, on several dimensions, including emotional content. Implications for aggression-related memory more generally as well as false confessions are discussed. PMID:23639921

  7. SCADA Application for ACTS Technology

    NASA Technical Reports Server (NTRS)

    Fairbanks, Barry

    1992-01-01

    The results of a system level study done by Hughes Network Systems for NASA are presented. For the supervisory control and data acquisition (SCADA) application, use of Ka-band spot beam satellite technology associated with NASA's Advanced Communication Technology Satellite (ACTS) offers a reduction in Earth station antenna size and transmitter power that may translate into lower system costs. The approaches taken to determine commercial potential of the system are described.

  8. Clean Air Act. Revision 5

    SciTech Connect

    Not Available

    1994-02-15

    This Reference Book contains a current copy of the Clean Air Act, as amended, and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. This Reference Book has been completely revised and is current through February 15, 1994.

  9. Elder Justice Act of 2009

    THOMAS, 111th Congress

    Rep. Rangel, Charles B. [D-NY-15

    2009-09-17

    03/23/2010 Became Public Law No: 111-148. (TXT | PDF) (All Actions) Notes: H.R.4872 makes a number of health-related financing and revenue changes to this bill. Read together, this bill and the health care-related provisions of H.R.4872 are commonly referred to as the Affordable Care Act (ACA). Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  10. Overview of the ACT program

    NASA Technical Reports Server (NTRS)

    Davis, John G., Jr.

    1992-01-01

    NASA's Advanced Composites Program (ACT) was initiated in 1988. A National Research Announcement was issued to solicit innovative ideas that could significantly contribute to development and demonstration of an integrated technology data base and confidence level that permits cost-effective use of composite primary structures in transport aircraft. Fifteen contracts were awarded by the Spring of 1989 and the participants include commercial and military airframe manufacturers, materials developers and suppliers, universities, and government laboratories. The program approach is to develop materials, structural mechanics methodology, design concepts, and fabrication procedures that offer the potential to make composite structures cost-effective compared to aluminum structure. Goals for the ACT program included 30-50 percent weight reduction, 20-25 percent acquisition cost reduction, and provided the scientific basis for predicting materials and structures performance. This paper provides an overview of the ACT program status, plans, and selected technical accomplishments. Sixteen additional papers, which provide more detailed information on the research and development accomplishments, are contained in this publication.

  11. Multimedia regulated chemicals

    SciTech Connect

    Lee, C.C.; Huffman, G.L.; Mao, Y.L.

    1999-10-01

    This article examines those chemicals that are listed in either environmental laws or regulations. Its objective is to help readers determine which laws regulate what types of chemicals and which types of chemicals are regulated by what laws. It is multimedia in scope, describing the various chemicals that are regulated in the different media (i.e., air, water, or land).

  12. The chemical life(1).

    PubMed

    Hodges, Nathan

    2015-01-01

    You write this narrative autoethnography to open up a conversation about our chemical lives. You go through your day with chemical mindfulness, questioning taken-for-granted ideas about natural and artificial, healthy and unhealthy, dependency and addiction, trying to understand the chemical messages we consume through the experiences of everyday life. You reflect on how messages about chemicals influence and structure our lives and why some chemicals are celebrated and some are condemned. Using a second-person narrative voice, you show how the personal is relational and the chemical is cultural. You write because you seek a connection, a chemical bond. PMID:24905820

  13. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 2 2013-01-01 2013-01-01 false Effect of Interlocks Act on Clayton Act. 212.9... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have...

  14. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Effect of Interlocks Act on Clayton Act. 212.9... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have...

  15. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Effect of Interlocks Act on Clayton Act. 212.9... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have...

  16. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Effect of Interlocks Act on Clayton Act. 212.9... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have...

  17. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Effect of Interlocks Act on Clayton Act. 212.9... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have...

  18. PINS chemical identification software

    DOEpatents

    Caffrey, Augustine J.; Krebs, Kennth M.

    2004-09-14

    An apparatus and method for identifying a chemical compound. A neutron source delivers neutrons into the chemical compound. The nuclei of chemical elements constituting the chemical compound emit gamma rays upon interaction with the neutrons. The gamma rays are characteristic of the chemical elements constituting the chemical compound. A spectrum of the gamma rays is generated having a detection count and an energy scale. The energy scale is calibrated by comparing peaks in the spectrum to energies of pre-selected chemical elements in the spectrum. A least-squares fit completes the calibration. The chemical elements constituting the chemical compound can be readily determined, which then allows for identification of the chemical compound.

  19. 40 CFR 799.18 - Chemicals subject of test rules or consent orders for which the testing reimbursement period has...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... action under TSCA section 5, 6, or 7 (in addition to final actions under section 4); see 40 CFR part 707... 13, 1994 62-53-3 Aniline 53 FR 31804, 8/19/88 July 27, 1994 71-55-6 1,1,1-Trichloroethane 49 FR...

  20. 40 CFR 799.18 - Chemicals subject of test rules or consent orders for which the testing reimbursement period has...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... action under TSCA section 5, 6, or 7 (in addition to final actions under section 4); see 40 CFR part 707... 13, 1994 62-53-3 Aniline 53 FR 31804, 8/19/88 July 27, 1994 71-55-6 1,1,1-Trichloroethane 49 FR...