Career Readiness in the United States 2015. ACT Insights in Education and Work
ERIC Educational Resources Information Center
LeFebvre, Mary
2015-01-01
ACT has conducted over 20,000 job analyses for occupations across a diverse array of industries and occupations since 1993. This report highlights the levels of career readiness for various subgroups of ACT Work Keys® examinees in the United States and provides career readiness benchmarks for selected ACT WorkKeys cognitive skills by career…
ERIC Educational Resources Information Center
Clark, Hope
2013-01-01
In this report, ACT presents a definition of "work readiness" along with empirically driven ACT Work Readiness Standards and Benchmarks. The introduction of standards and benchmarks for workplace success provides a more complete picture of the factors that are important in establishing readiness for success throughout a lifetime. While…
Barriers to vocational effectiveness in ACT: staff perspectives.
Waynor, William R; Pratt, Carlos W
2011-01-01
Assertive community treatment (ACT), for persons with serious mental illness, includes a vocational focus as an important aspect of community integration. Nevertheless, research suggests that ACT does not assist significant numbers of consumers in achieving employment goals. A two-step survey of New Jersey ACT team members was designed to identify the key issues that hinder ACT staff members in assisting consumers with obtaining employment. Survey items were categorized into three sections: (a) staff attitudes, (b) consumer barriers, and (c) staff barriers to working on employment. The initial survey asked staff members to rate items in each of these categories. Highly rated items were used in a subsequent paired comparison survey to determine the relative importance of each. This method highlighted the following issues: four staff attitude items-(a) returning to work is positive, (b) employment is key to recovery, (c) abstinence from substance abuse is needed to work, and (d) consumers are too ill to work; four consumer barrier items-(a) fear of loss of Social Security Administration benefits, (b) symptoms related to the illness, (c) lack of motivation, and (d) poor social skills; and three barriers to working on employment issues items-(a) clinical issues take priority, (b) other case management issues takes priority, and (c) too many emergencies. The implications for staff training are discussed.
Mental Capacity Act 2005: statutory principles and key concepts.
Griffith, Richard; Tengnah, Cassam
2008-05-01
The Mental Capacity Act 2005 represents the most significant development in the law relating to people who lack decision making capacity since the Mental Health Act 1959 removed the states parens patriae jurisdiction preventing relatives, courts and government bodies consenting on behalf of incapable adults (F vs West Berkshire HA [1990]). The Mental Capacity Act 2005 impacts on the care and treatment provided by district nurses and it is essential that you have a sound working knowledge of its provisions and code of practice. In the first article of a series focusing on how the Mental Capacity Act 2005 applies to district nurse practice, Richard Griffith and Cassam Tengnah consider the principles and key concepts underpinning the Act.
The Innovative Technology Deployment (ITD) Grant Program, 2017 Annual Report
DOT National Transportation Integrated Search
2018-05-01
On December 4, 2015, the Fixing America's (FMCSA) works to reduce crashes, injuries, and Surface Transportation Act, 2015 (FAST Act) fatalities involving large trucks and buses. (Pub. L. 114-94) established the Innovative The ITD program is a key com...
ERIC Educational Resources Information Center
Jozefowicz-Simbeni, Debra M. Hernandez; Israel, Nathaniel
2006-01-01
In 1987 Congress authorized the Stewart B. McKinney Homeless Assistance Act to protect the rights of homeless students and to ensure that they receive the same quality and appropriate education that other students receive. This article summarizes key aspects of the 2001 reauthorization of the act, now known as the McKinney-Vento Act, outlines how…
2003-12-01
The 'work-life balance' and flexible working are currently key buzz terms in the NHS. Those looking for more information on these topics should visit Flexibility at www.flexibility.co.uk for a host of resources designed to support new ways of working, including information on flexible workers and flexible rostering, the legal balancing act for work-life balance and home working.
29 CFR 825.217 - Key employee, general rule.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825...-date earnings are divided by weeks worked by the employee (including weeks in which paid leave was...
29 CFR 825.217 - Key employee, general rule.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... are divided by weeks worked by the employee (including weeks in which paid leave was taken). Earnings...
29 CFR 825.217 - Key employee, general rule.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825...-date earnings are divided by weeks worked by the employee (including weeks in which paid leave was...
29 CFR 825.217 - Key employee, general rule.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... are divided by weeks worked by the employee (including weeks in which paid leave was taken). Earnings...
Timeline: Targeted Treatment of Hepatitis C Virus.
Teitzel, Gail
2016-09-22
Chronic hepatitis C virus infection can cause liver cirrhosis and cancer, and early treatment options were non-specific and could be toxic. Work aimed at elucidating the viral life cycle has led to better treatment options through the development of direct-acting antivirals, as exemplified by the work of Ralf Bartenschlager, Charles Rice, and Michael Sofia who have received the Lasker∼DeBakey Clinical Medical Research Award for their work on this effort. Key events in understanding HCV replication and development of direct-acting antivirals are shown in this Timeline. Copyright © 2016 Elsevier Inc. All rights reserved.
Three-Dimensional Pedagogy: A New Professionalism in Educational Contexts
ERIC Educational Resources Information Center
Andrews, Dorothy; Abawi, Lindy
2017-01-01
This article provides evidence of a new teacher professionalism whereby teachers, acting as collaborative individuals working together, are the key to effectively meeting the needs of diverse student cohorts. Drawing on data from Australian school contexts and the work of researchers from the Leadership Research International team, new…
A new approach in psychotherapy: ACT (acceptance and commitment therapy).
McHugh, Louise
2011-09-01
Acceptance and commitment therapy (ACT) focuses on enhancing psychological flexibility in the service of achieving core life values. One thing that distinguishes ACT from other psychotherapies is its grounding in empirical behavioural science. The results of the latter suggest that the capacity for human language can produce seriously negative psychological effects under certain circumstances. ACT is a therapeutic approach in which the negative effects of human language are undermined so as to support flexible values based living. ACT therapeutic work involves six key processes proposed under the "hexaflex" model. ACT has received considerable empirical support at a number of different levels of analysis.
ERIC Educational Resources Information Center
Office of Vocational and Adult Education (ED), Washington, DC.
In preparation for reauthorization of the Adult Education and Family Literacy Act (AEFLA), the Bush administration outlined its vision for adult basic and literacy education. Key principles of that vision are as follows: (1) creating accountability for results; (2) funding that works; (3) expanding options and choices for students; and (4)…
Key Working for Families with Young Disabled Children
Carter, Bernie; Thomas, Megan
2011-01-01
For families with a disabled child, the usual challenges of family life can be further complicated by the need to access a wide range of services provided by a plethora of professionals and agencies. Key working aims to support children and their families in navigating these complexities ensuring easy access to relevant, high quality, and coordinated care. The aim of this paper is to explore the key worker role in relation to “being a key worker” and “having a key worker”. The data within this paper draw on a larger evaluation study of the Blackpool Early Support Pilot Programme. The qualitative study used an appreciative and narrative approach and utilised mixed methods (interviews, surveys and a nominal group workshop). Data were collected from 43 participants (parents, key workers, and other stakeholders). All stakeholders who had been involved with the service were invited to participate. In the paper we present and discuss the ways in which key working made a difference to the lives of children and their families. We also consider how key working transformed the perspectives of the key workers creating a deeper and richer understanding of family lives and the ways in which other disciplines and agencies worked. Key working contributed to the shift to a much more family-centred approach, and enhanced communication and information sharing between professionals and agencies improved. This resulted in families feeling more informed. Key workers acted in an entrepreneurial fashion, forging new relationships with families and between families and other stakeholders. Parents of young disabled children and their service providers benefited from key working. Much of the benefit accrued came from strong, relational, and social-professional networking which facilitated the embedding of new ways of working into everyday practice. Using an appreciative inquiry approach provided an effective and relevant way of engaging with parents, professionals, and other stakeholders to explore what was working well with key working within an Early Support Pilot Programme. PMID:21994827
[Medical cooperation on the internet].
Meier, N; Lenzen, H; Renger, B C
1998-01-01
Post-1999, the economically united EEC will pose new challenges to European business, industry and citizen. It is a key objective that in the domain of European "infostructure" these problems are challenged and overcome, and that "advanced communications technologies and services" (ACTS) become the cement which binds the Community together. Within ACTS, 130 different projects are building new services. The consortium Emerald develops a telemedicine platform, setting up teleworking with teleconference, computer supported co-operative work (cscw, joint editing), demonstration and teleteaching for radiology, cardiology, nuclear medicine and radio surgery working environments.
Demystifying governance and its role for transitions in urban social–ecological systems
T.A. Muñoz-Erickson; L.K. Campbell; D.L. Childers; J.M. Grove; D.M. Iwaniec; S.T.A. Pickett; Michelle Romolini; Erika S. Svendsen
2016-01-01
Governance is key to sustainable urban transitions. Governance is a system of social, power, and decision-making processes that acts as a key driver of resource allocation and use, yet ecologists even urban ecologistsâseldom consider governance concepts in their work. Transitions to more sustainable futures are becoming increasingly important to the management of many...
Roulstone, Alan; Hudson, Val
2007-06-01
Much policy and practice attention has been focused on the participation and involvement of informal carers in service assessment, provision and review. The advent of the National Carers Strategy, the Community Care Delayed Discharge Act, Carers and Disabled Children Act and latterly the Carers (Equal Opportunities) Act have all played their part in giving greater significance to carer involvement. The role of professional cooperation and willingness to see carers as equal partners is a key factor in achieving these objectives. This paper relates details of a study of current carer participation in England, Wales and Northern Ireland and begs a number of important questions as to the challenges for interprofessional working in supporting carer participation.
25 CFR 309.2 - What are the key definitions for purposes of the Act?
Code of Federal Regulations, 2011 CFR
2011-04-01
... “made by an Indian” means that an Indian has provided the artistic or craft work labor necessary to implement an artistic design through a substantial transformation of materials to produce the art or craft... Indian artistic or craft work labor; (v) Industrial products, which for this purpose are defined as goods...
41 CFR Appendix A to Subpart D of... - 3-Key Points and Principles
Code of Federal Regulations, 2011 CFR
2011-01-01
..., transcripts, minutes, appendixes, working papers, drafts, studies, agenda, or other documents which were made... accordance with the Federal Records Act (FRA), 44 U.S.C. Chapters 21, 29-33, and regulations issued by the...
41 CFR Appendix A to Subpart D of... - 3-Key Points and Principles
Code of Federal Regulations, 2013 CFR
2013-07-01
..., transcripts, minutes, appendixes, working papers, drafts, studies, agenda, or other documents which were made... accordance with the Federal Records Act (FRA), 44 U.S.C. Chapters 21, 29-33, and regulations issued by the...
41 CFR Appendix A to Subpart D of... - 3-Key Points and Principles
Code of Federal Regulations, 2012 CFR
2012-01-01
..., transcripts, minutes, appendixes, working papers, drafts, studies, agenda, or other documents which were made... accordance with the Federal Records Act (FRA), 44 U.S.C. Chapters 21, 29-33, and regulations issued by the...
41 CFR Appendix A to Subpart D of... - 3-Key Points and Principles
Code of Federal Regulations, 2014 CFR
2014-01-01
..., transcripts, minutes, appendixes, working papers, drafts, studies, agenda, or other documents which were made... accordance with the Federal Records Act (FRA), 44 U.S.C. Chapters 21, 29-33, and regulations issued by the...
The Balancing Act: Lessons From A Non-Linear Career
NASA Astrophysics Data System (ADS)
Matson, P.
2007-12-01
Careful planning of one's career seldom works as expected. We will discuss some key approaches to decision making about career steps, and strategies for navigating the opportunities and challenges of a dynamic geosciences career and family life.
Who is Responsible for Defending United States Interests in Cyberspace?
2013-03-01
The U.S. Chamber of Commerce worked openly to challenge legislation that potentially would have directed minimum standards for operators of key...of companies to enable private public collaboration to 6 protect critical infrastructure as the U.S. Chamber of Commerce actively identifies...cyberspace-lawmakers-say/50869/ (accessed November 12, 2012). 19 US Chamber of Commerce , “Key Vote letter on S. 3414, the Cybersecurity Act of 2012
Texas Hold'em: Secretary Spellings--the Ace in Bush's Hand
ERIC Educational Resources Information Center
Davis, Michelle R.
2007-01-01
President Bush has one ace in his hand when it comes to the No Child Left Behind Act (NCLB): Secretary of Education Margaret Spellings. Spellings, who has been working on education issues for Bush since the 1990s and his days as a Texas governor, is the person who from the very beginning has had to make NCLB work. She was a key architect of the…
Introducing IT Strategy in an Introductory Course
ERIC Educational Resources Information Center
Woods, David M.
2016-01-01
Professionals working in technology fields face continuing challenges to be involved in the decision-making process about how technology is used by organizations rather than just implementing these decisions. Developing skills for thinking and acting strategically are key skills for our students. This has been recognized by the addition of an IS…
Economic Conditions and Welfare Reform.
ERIC Educational Resources Information Center
Danziger, Sheldon H., Ed.
This book contains 10 papers on three key questions regarding the effects of the 1996 Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA), which ended the Aid to Families with Dependent Children (AFDC) program: why welfare caseloads are falling; how welfare recipients are faring; and how the states are responding to changing…
ERIC Educational Resources Information Center
Anderson, Byron
2007-01-01
The Internet's breakthrough to primetime usage beginning in the mid-1990s evolved in an era of openness. Unfettered access seemed key to Internet development. An important foundation for the 1996 Telecommunications Act was the theory that the telecom industry would work best if it were free of government regulation, a guiding principle that has…
Bohme, Susanna Rankin; Egilman, David
2008-01-01
In his article in this issue, Tee Guidotti casts recent works addressing corporate influence on occupational medicine as "collective act[s] of disparagement ... undertaken ... for political reasons." We move beyond the question of reputation to address key conflicts in the history of occupational medicine, including the American Occupational Medical Association's historical role in weakening the beryllium standard and the American College of Occupational and Environmental Medicine's recent efforts to limit the extent of the Family Medical Leave Act. The corporate practice of externalizing health and safety costs makes industry influence an important ongoing topic of debate in occupational and environmental medicine.
NASA and Industry Benefits of ACTS High Speed Network Interoperability Experiments
NASA Technical Reports Server (NTRS)
Zernic, M. J.; Beering, D. R.; Brooks, D. E.
2000-01-01
This paper provides synopses of the design. implementation, and results of key high data rate communications experiments utilizing the technologies of NASA's Advanced Communications Technology Satellite (ACTS). Specifically, the network protocol and interoperability performance aspects will be highlighted. The objectives of these key experiments will be discussed in their relevant context to NASA missions, as well as, to the comprehensive communications industry. Discussion of the experiment implementation will highlight the technical aspects of hybrid network connectivity, a variety of high-speed interoperability architectures, a variety of network node platforms, protocol layers, internet-based applications, and new work focused on distinguishing between link errors and congestion. In addition, this paper describes the impact of leveraging government-industry partnerships to achieve technical progress and forge synergistic relationships. These relationships will be the key to success as NASA seeks to combine commercially available technology with its own internal technology developments to realize more robust and cost effective communications for space operations.
A New Approach to PD--and Growing Leaders
ERIC Educational Resources Information Center
Baum, Kenneth; Krulwich, David
2017-01-01
Why don't most well-meaning efforts to improve teaching and grow key teachers' capacity to act as instructional leaders show success? Kenneth Baum and David Krulwich think they know why: While we set up "collaborative" procedures and meetings in which teachers work together to explore effective instruction--critical friends groups, data…
75 FR 21871 - Spring 2010 Regulatory Agenda
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-26
... Entities J. What Other Special Attention Do We Give to the Impacts of Rules on Small Businesses, Small..., Administrator Jackson has outlined seven themes to focus the work of EPA. These key goals shape everything we do... under section 610 of the Regulatory Flexibility Act (RFA) (5 U.S.C. 610). Priority: Entries are placed...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-13
... collected on members of the general public, health professionals, faculty of academic institutions, students... peers on healthy living and pre-conception care. 5. Organizational Databases: Business contact... to work. 3. Organizational Databases: Name of organization and key contact person, business address...
Applied Technology Proficiency of High School Students in Applied and Traditional Courses
ERIC Educational Resources Information Center
Field, Dennis W.
2003-01-01
This investigation compares applied technology skill levels of high school students enrolled in various applied and comparable traditional courses, particularly Principles of Technology and physics courses respectively. Outcomes from ACT's Applied Technology Work Keys[R] assessment test were used as a measure of applied technology skill levels.…
Speaking the Same Language: Developing a Language-Aware Feedback Culture
ERIC Educational Resources Information Center
Lazar, Gillian; Ryder, Agi
2018-01-01
Research suggests that feedback as part of assessment is often not delivered effectively. A key aspect of effective feedback delivery is that students need to understand feedback and also feel motivated to act on it. This article explores how educational developers can incorporate a language-aware approach to feedback when working with staff…
Pearson, Charlotte; Watson, Nick
2018-05-01
Health and social care integration has been a long-term goal for successive governments in Scotland, culminating in the implementation of the recent Public Bodies (Joint Working) Scotland Act 2014. This laid down the foundations for the delegation of health and social care functions and resources to newly formed Integrated Joint Boards. It put in place demands for new ways of working and partnership planning. In this article, we explore the early implementation of this Act and how health and social care professionals and the third sector have begun to renegotiate their roles. The paper draws on new empirical data collated through focus groups and interviews with over 70 professionals from across Scotland. The data are explored through the following key themes: changing cultures, structural imbalance, governance and partnership and the role of individuals or "boundary spanners" in implementing change. We also draw on evidence from other international systems of care, which have implemented integration policies, documenting what works and what does not. We argue that under the current framework much of the potential for integration is not being fulfilled and that the evidence suggests that at this early stage of roll-out, the structural and cultural policy changes that are required to enable this policy shift have not yet emerged. Rather, integration has been left to individual innovators or "boundary spanners" and these are acting as key drivers of change. Where change is occurring, this is happening despite the system. As it is currently structured, we argue that too much power is in the hands of health and despite the rhetoric of partnership working, there are real structural imbalances that need to be reconciled. © 2018 John Wiley & Sons Ltd.
Sociopolitical contexts of self-immolations in Vietnam and South Korea.
Ben Park, B C
2004-01-01
This article explores common political and social-psychological factors involved in acts of self-immolation that took place in Vietnam and South Korea in the later part of the 20th century. Drawing upon the pioneering work of Emile Durkheim, the author identifies some key analytical distinctions between altruistic suicide and cases of self-immolation. On the basis of suicide notes, diaries, and letters left behind by 22 self-immolators, the author sheds light on the intentions and beliefs of those actors and social significance of their acts. In addition to the unique geo-political circumstances of the Cold War era, under which massive numbers of dramatic public acts of self-immolation took place, the symbolic message imbedded in the acts of self-immolators is explored.
Understanding suffering and giving compassion: the reach of socially engaged Buddhism into China.
Kuah-Pearce, Khun Eng
2014-01-01
This paper will explore the social engagement of Buddhists through their active voluntary works - works that result in the development of a religious philanthropic culture. Through three case examples, this paper will examine how the sangha and individual Buddhists understand social suffering and compassion and attempt to integrate their understanding of Buddhist virtues and values in their daily life where the performance of voluntary works is seen as Buddhist spiritualism. In this process, the individuals seek to understand the key principles of Buddhism that are of direct relevance to their daily existence and their quest to be a compassionate self. Foremost are two notions of yebao (karma) and gan-en (gratitude) and how through compassionate practices and gratitude for those who accepted compassionate acts, they would be rewarded with good karma. Here, pursuing compassionate acts and the alleviation of social suffering is the pursuit of this-worldly spiritualism.
Concealment of Child Sexual Abuse in Sports
ERIC Educational Resources Information Center
Hartill, Mike
2013-01-01
When the sexual abuse of children is revealed, it is often found that other nonabusing adults were aware of the abuse but failed to act. During the past twenty years or so, the concealment of child sexual abuse (CSA) within organizations has emerged as a key challenge for child protection work. Recent events at Pennsylvania State University (PSU)…
ERIC Educational Resources Information Center
Ellyn, Tracy
2005-01-01
"Lwa" is the term given to spirits who are believed to act as intermediaries in the lives of Haitians. Many Haitians call upon the "lwa" daily for their problem-solving abilities. The goal of any artist is to be one with his or her own artwork. When working with young art students, this is the key to keeping them on task. For…
Wilson, Eleanor; Seymour, Jane E; Perkins, Paul
2010-06-01
Since October 2007 staff across health and social care services in England and Wales have been guided by the Mental Capacity Act (2005) in the provision of care for those who may lack capacity to make some decisions for themselves. This paper reports on the findings from a study with 26 staff members working in three palliative and three neurological care centres. Semistructured interviews were used to gain an understanding of their knowledge of the Mental Capacity Act, the issue of capacity itself and the documentation processes associated with the introduction of the Act and in line with advance care planning. Within this setting advance care planning is a key part of care provision and the mental capacity of service users is a regular issue. Findings show that staff generally had a good understanding of issues around capacity but felt unclear about some of the terminology related to the Mental Capacity Act, impacting on their confidence to discuss issues with service users and complete the documentation. Many felt the Act and its associated documentation had aided record-keeping in an area staff already delivered well in practice. Advance care planning in the context of the Mental Capacity Act is not as well embedded in practice as providers would like and consideration needs to be given to how and when staff should approach these issues with service users.
NASA Astrophysics Data System (ADS)
Akrout, Nabil M.; Gordon, Howard; Palisson, Patrice M.; Prost, Remy; Goutte, Robert
1996-05-01
Facing a world undergoing fundamental and rapid change, healthcare organizations are seeking ways to increase innovation, quality, productivity, and patient value, keys to more effective care. Individual clinics acting alone can respond in only a limited way, so re- engineering the process key which services are delivered demands real-time collaborative technology that provides immediate information sharing, improving the management and coordination of information in cross-functional teams. StreamWorks is a development stage architecture that uses a distribution technique to deliver an advanced information management system for telemedicine. The challenge of StreamWorks in telemedicine is to enable equity of the quality of Health Care of Telecommunications and Information Technology also to patients in less favored regions, like India or China, where the quality of medical care varies greatly by region, but where there are some very current communications facilities.
ERIC Educational Resources Information Center
Deming, David J.; Cohodes, Sarah; Jennings, Jennifer; Jencks, Christopher
2016-01-01
When congress passed the No Child Left Behind Act of 2001 (NCLB), standardized testing in public schools became the law of the land. The ambitious legislation identified test-based accountability as the key to improving schools and, by extension, the long-term prospects of American schoolchildren. Thirteen years later, the debate over the federal…
Development and Validation of ENGAGE[TM] Grades 6-9. ACT Research Report Series, 2011-1
ERIC Educational Resources Information Center
Casillas, Alex; Allen, Jeff; Kuo, Yi-Lung; Pappas, Susan; Hanson, Mary Ann; Robbins, Steve
2011-01-01
This report details the development and validation of the ENGAGE Grades 6-9, a measure of academic behavior designed to determine students' levels of academic risk. The work presented in this report is part of a comprehensive research program of educational risk assessment based on key academic behavior predictors (also known in the literature as…
ERIC Educational Resources Information Center
National Council on Disability, Washington, DC.
This study was commissioned to determine how the Individuals with Disabilities Education Act is working, what outcomes children and youth with disabilities are achieving, and how the system can be improved in the context of current education reform initiatives. Key policy themes addressed include individualized education programs, least…
The balancing act: key issues in the lives of women general practitioners in Australia.
Kilmartin, Margaret R; Newell, Christopher J; Line, Martin A
2002-07-15
To identify key issues affecting women general practitioners in their professional and non-professional lives. A qualitative study using the Delphi technique, with three rounds of data provision circulated to each participant. Coding was used to ensure anonymity. The participants were a purposive sample of 40 women GPs drawn from all Australian States and Territories. The study was conducted between October 1996 and January 1997. Key issues affecting the professional and non-professional lives of women GPs. Some of the key professional issues for women GPs were job satisfaction, balancing work and personal life, autonomy, availability of flexible and part-time work and training, affordability of professional expenses, fair remuneration, and having a voice in decision-making. Key non-professional issues included self-care; time for relationships with a partner, children, family and friends; and time management to allow pursuit of non-medical interests. The conflicting demands made on women GPs diminish their job satisfaction and lead to stress and imbalance in their lives. Recommendations to ameliorate the problems for women GPs include appropriate training, policy formation, financial and other support, and a change in cultural expectations of women GPs by the community, the profession and governments.
Rising to the challenge: Deep acting is more beneficial when tasks are appraised as challenging.
Huang, Jason L; Chiaburu, Dan S; Zhang, Xin-an; Li, Ning; Grandey, Alicia A
2015-09-01
Cumulative research indicates that deep acting has a nonsignificant relationship with employee exhaustion, despite arguments that deep acting can be beneficial. To illuminate when deep acting leads to more positive employee outcomes, we draw on the resource conservation perspective to propose a within-individual model of deep acting that focuses on service employees' daily fluctuation of emotional labor and emotional exhaustion. Specifically, we propose that the ongoing experience of felt challenge is a within-person boundary condition that moderates deep acting's relationship with emotional exhaustion, and model emotional exhaustion as a mediating mechanism that subsequently predicts momentary job satisfaction and daily customer conflict handling. Using an experience sampling design, we collected data from 84 service employees over a 3-week period. Deep acting was less emotionally exhausting for service providers when they saw their tasks as more challenging. Furthermore, emotional exhaustion mediated the deep acting by felt challenge interaction effect on momentary job satisfaction and daily customer conflict handling. The findings contribute to a better understanding of the deep acting experience at work, while highlighting customer conflict handling as a key behavioral outcome of emotional labor. (c) 2015 APA, all rights reserved).
Secco, David; Wang, Chuang; Shou, Huixia; Whelan, James
2012-02-17
In the yeast Saccharomyces cerevisiae, a working model for nutrient homeostasis in eukaryotes, inorganic phosphate (Pi) homeostasis is regulated by the PHO pathway, a set of phosphate starvation induced genes, acting to optimize Pi uptake and utilization. Among these, a subset of proteins containing the SPX domain has been shown to be key regulators of Pi homeostasis. In this review, we summarize the recent progresses in elucidating the mechanisms controlling Pi homeostasis in yeast, focusing on the key roles of the SPX domain-containing proteins in these processes, as well as describing the future challenges and opportunities in this fast-moving field. Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Kinsella, Valerie, Ed.
The articles in this volume are an overview of work in a number of subjects and disciplines which contribute to the field of applied linguistics and language teaching. Specifically, they treat universal properties common to all languages, the historical developments and central issues in speech act theory, speech research on the various stages of…
Disrupting Threat Finances: Using Financial Information to Disrupt Terrorist Organizations
2008-04-01
remittance systems, stored value cards, digital currency , and Islamic banking; b) not-for-profit organizations, including front organizations and...including cash couriers; alternative remittance systems “informal value transfer,” such as hawalas and hundis; stored value cards; digital currency ...work with other federal agencies to implement key statutory provisions of the Currency and Foreign Transactions Report- ing Act (commonly referred to
Creatine as a booster for human brain function. How might it work?
Rae, Caroline D; Bröer, Stefan
2015-10-01
Creatine, a naturally occurring nitrogenous organic acid found in animal tissues, has been found to play key roles in the brain including buffering energy supply, improving mitochondrial efficiency, directly acting as an anti-oxidant and acting as a neuroprotectant. Much of the evidence for these roles has been established in vitro or in pre-clinical studies. Here, we examine the roles of creatine and explore the current status of translation of this research into use in humans and the clinic. Some further possibilities for use of creatine in humans are also discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Ushakova, A.; Emelyanov, D.; Zatsepin, V.; Varfolomeev, M.
2018-05-01
The formation and decomposition of hydro-peroxides are the key stages of combustion. These stages strongly depend on the several factors accelerating or slowing this process. The aim of this work is to estimate experimentally which oil components act as inhibitors of initial stages of oxidation and which accelerate the process. The next aim is to explore the process of adsorption of oil components on the grain of rock, which turned to be also a key process in the low temperature oxidation. The work includes experimental part where differential scanning calorimeter (PDSC) experiments with pure saturates, mixtures of saturates and aromatic oil fractions and mixtures of saturates, aromatic fractions and rock samples are considered. Effects of inhibition and acceleration of the initial oxidation stages are explored.
The Spanish version of the Work-related Acceptance and Action Questionnaire (WAAQ).
Ruiz, Francisco J; Odriozola-González, Paula
2014-01-01
Psychological flexibility, a key construct of Acceptance and Commitment Therapy (ACT), has recently been found to be an important determinant of mental health and behavioral effectiveness in the workplace. This finding has led to designing a measure of psychological flexibility especially tailored to the workplace (the Work-related Acceptance and Action Questionnaire; WAAQ) in the hope that it may reveal even stronger associations with variables related to a work context. First, we back-translated the WAAQ into Spanish and then administered it to 209 workers, in addition to other relevant work-related measures. Data were very similar to those obtained with the original WAAQ version. The WAAQ showed a very good internal consistency (a = .92) and a clear one-factor structure. It also showed higher correlations with work-specific measures than a general measure of psychological inflexibility (the Acceptance and Action Questionnaire-II; AAQ-II). As hypothesized by the ACT theory, the correlation between the WAAQ and the AAQ-II was moderate but not so high as to suggest that they are assessing the same construct. This Spanish translation of the WAAQ emerges as a reliable and valid measure of psychological flexibility in relation to the workplace.
ERIC Educational Resources Information Center
Bettinger, Eric; Baker, Rachel
2011-01-01
College completion and college success often lag behind college attendance. One theory as to why students do not succeed in college is that they lack key information about how to be successful or fail to act on the information that they have. We present evidence from a randomized experiment which tests the effectiveness of individualized student…
The assemblage of compliance in psychiatric case management.
Brodwin, Paul
2010-08-01
In the post-asylum era, case managers perform much of the face-to-face work of pharmaceutical compliance for people with severe and persistent mental illness. Their work demands careful orchestration of the assemblage of compliance, including the actual medications, the ideology of biopsychiatry, the division of professional labor, and certain mundane tools. Ethnographic vignettes from an Assertive Community Treatment (ACT) team show how case managers use this assemblage in their everyday routines, but also how it undercuts key elements of the original ACT mission. Reflecting its roots in the deinstitutionalization movement, the ACT model gives case managers limitless responsibilities for clients' lives, but then narrowly defines their role as the prosthetic extension of psychiatric authority. To produce compliance, case managers depend on the medication cassette, analyzed here as a human/non-human hybrid woven into their ordinary work. The medication cassette has pre-scripted uses that enlist clinicians in biopsychiatric thinking and also silently impose compliant behavior on clients. The elements in the assemblage of compliance depend on each other, but they do not form a seamless whole, as evidenced by the dilemmas and micropolitics of the clinical front-line. Theoretical notions of assemblages and technologies of compliance, drawn from science and technology studies, illuminate a core conundrum of practice in psychiatric case management.
Superconducting-circuit quantum heat engine with frequency resolved thermal baths
NASA Astrophysics Data System (ADS)
Hofer, Patrick P.; Souquet, Jean-René; Clerk, Aashish A.
The study of quantum heat engines promises to unravel deep, fundamental concepts in quantum thermodynamics. With this in mind, we propose a novel, realistic device that efficiently converts heat into work while maintaining reasonably large output powers. The key concept in our proposal is a highly peaked spectral density in both the thermal baths as well as the working fluid. This allows for a complete separation of the heat current from the working fluid. In our setup, Cooper pairs tunnelling across a Josephson junction serve as the the working fluid, while two resonant cavities coupled to the junction act as frequency-resolved thermal baths. The device is operated such that a heat flux carried entirely by the photons induces an electrical current against a voltage bias, providing work.
Gioia, Deborah; Brekke, John S
2003-01-01
Employment is an important outcome for individuals with schizophrenia and the Americans with Disabilities Act (ADA) is a key structural variable designed to favorably influence work. Little is known about how individuals understand and utilize ADA rights. The purpose of this mixed method study was to elicit understanding of the knowledge and use of ADA provisions from 20 persons with schizophrenia who returned to work. Three distinct groups emerged. Group differences suggest that use of ADA provisions may be dependent on individual need and comfort with ADA opportunity.
Commentary: what role for the family and Medical Leave Act in long-term care policy?
Wisensale, Steven K
2006-01-01
The Family and Medical Leave Act provides unpaid leave but a key component is its intergenerational structure, permitting employees to take time off from work to care for an infant as well as an ill elderly parent. However, in an effort to provide paid leave, 23 of 28 states dropped the elder care provision in new initiatives introduced between 2000 and 2003. This article argues that in reforming leave policy in the future, the leave should be paid, remain intergenerational, cover more workers, and be adaptable to changing family patterns in an aging society. Also discussed is California's paid leave law, which meets these criteria.
ERIC Educational Resources Information Center
Weil, Alan
This brief presents 10 key findings about welfare reform, using research from the Urban Institute's Assessing the New Federalism project. Welfare reform has taken hold, and, in the immediate aftermath of the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA), states have made major changes to their welfare systems that…
Battered Wives or Dependent Mothers? Negotiating Familial Ideology in Law.
Kodikara, Chulani
2018-06-01
More than a decade after its passing, Sri Lanka's Prevention of Domestic Violence Act (PDVA) remains a remedy of last resort for female survivors of intimate partner violence, as there is little support to take on a rights-defined identity as a battered woman both inside and outside the courtroom. However, large numbers of women are accessing the Maintenance Act of 1999 to exit violent relationships without the censure and stigma that attaches to the PDVA. The key to understanding this phenomenon is to consider how familial ideology works in unpredictable ways within the Sri Lankan judicial system. This article examines the reach and different impacts of familial ideology within the judiciary and argues that female survivors of violence navigate this ideology to their own advantage. However, the preference to address violence through the Maintenance Act renders such violence invisible. The price for judicial redress is silence.
Freedom of Information Act Requests: Six Keys to Handling Them
2016-01-01
Defense AT&L: January–February 2016 50 Freedom of Information Act Requests Six Keys to Handling Them Michael A. Rodgers Rodgers is a professor of...crucial mission tasks. Understanding and using the six steps and keys provided above will free you from FOIA-induced distractions. The author can be contacted at michael.rodgers@dau.mil.
A conceptual framework of outcomes for caregivers of assistive technology users.
Demers, Louise; Fuhrer, Marcus J; Jutai, Jeffrey; Lenker, James; Depa, Malgorzata; De Ruyter, Frank
2009-08-01
To develop and validate the content of a conceptual framework concerning outcomes for caregivers whose recipients are assistive technology users. The study was designed in four stages. First, a list of potential key variables relevant to the caregivers of assistive technology users was generated from a review of the existing literature and semistructured interviews with caregivers. Second, the variables were analyzed, regrouped, and partitioned, using a conceptual mapping approach. Third, the key areas were anchored in a general stress model of caregiving. Finally, the judgments of rehabilitation experts were used to evaluate the conceptual framework. An important result of this study is the identification of a complex set of variables that need to be considered when examining the experience of caregivers of assistive technology users. Stressors, such as types of assistance, number of tasks, and physical effort, are predominant contributors to caregiver outcomes along with caregivers' personal resources acting as mediating factors (intervening variables) and assistive technology acting as a key moderating factor (effect modifier variable). Recipients' use of assistive technology can enhance caregivers' well being because of its potential for alleviating a number of stressors associated with caregiving. Viewed as a whole, this work demonstrates that the assistive technology experience of caregivers has many facets that merit the attention of outcomes researchers.
Working and Learning with Knowledge in the Lobes of a Humanoid's Mind
NASA Technical Reports Server (NTRS)
Ambrose, Robert; Savely, Robert; Bluethmann, William; Kortenkamp, David
2003-01-01
Humanoid class robots must have sufficient dexterity to assist people and work in an environment designed for human comfort and productivity. This dexterity, in particular the ability to use tools, requires a cognitive understanding of self and the world that exceeds contemporary robotics. Our hypothesis is that the sense-think-act paradigm that has proven so successful for autonomous robots is missing one or more key elements that will be needed for humanoids to meet their full potential as autonomous human assistants. This key ingredient is knowledge. The presented work includes experiments conducted on the Robonaut system, a NASA and the Defense Advanced research Projects Agency (DARPA) joint project, and includes collaborative efforts with a DARPA Mobile Autonomous Robot Software technical program team of researchers at NASA, MIT, USC, NRL, UMass and Vanderbilt. The paper reports on results in the areas of human-robot interaction (human tracking, gesture recognition, natural language, supervised control), perception (stereo vision, object identification, object pose estimation), autonomous grasping (tactile sensing, grasp reflex, grasp stability) and learning (human instruction, task level sequences, and sensorimotor association).
18-month-olds comprehend indirect communicative acts.
Schulze, Cornelia; Tomasello, Michael
2015-03-01
From soon after their first birthdays young children are able to make inferences from a communicator's referential act (e.g., pointing to a container) to her overall social goal for communication (e.g., to inform that a searched-for toy is inside; see Behne, Carpenter, & Tomasello, 2005; Behne, Liszkowski, Carpenter, & Tomasello, 2012). But in such cases the inferential distance between referential act and communicative intention is still fairly close, as both container and searched-for toy lie in the direction of the pointing gesture. In the current study we tested 18- and 26-month-old children in a situation in which referential act and communicative goal were more distant: In the midst of a game, the child needed a certain toy. The experimenter then held up a key (that they knew in common ground could be used to open a container) to the child ostensively. In two control conditions the experimenter either inadvertently moved the key and so drew the child's attention to it non-ostensively or else held up the key for her own inspection intentionally but non-communicatively. Children of both ages took only the ostensive showing of the key, not the accidental moving or the non-ostensive but intentional inspection of the key, as an indirect request to take the key and open the container to retrieve the toy inside. From soon after they start acquiring language young children thus are able to infer a communicator's social goal for communication not only from directly-referential acts, but from more indirect communicative acts as well. Copyright © 2014 Elsevier B.V. All rights reserved.
NCCN Biosimilars White Paper: regulatory, scientific, and patient safety perspectives.
Zelenetz, Andrew D; Ahmed, Islah; Braud, Edward Louis; Cross, James D; Davenport-Ennis, Nancy; Dickinson, Barry D; Goldberg, Steven E; Gottlieb, Scott; Johnson, Philip E; Lyman, Gary H; Markus, Richard; Matulonis, Ursula A; Reinke, Denise; Li, Edward C; DeMartino, Jessica; Larsen, Jonathan K; Hoffman, James M
2011-09-01
Biologics are essential to oncology care. As patents for older biologics begin to expire, the United States is developing an abbreviated regulatory process for the approval of similar biologics (biosimilars), which raises important considerations for the safe and appropriate incorporation of biosimilars into clinical practice for patients with cancer. The potential for biosimilars to reduce the cost of biologics, which are often high-cost components of oncology care, was the impetus behind the Biologics Price Competition and Innovation Act of 2009, a part of the 2010 Affordable Care Act. In March 2011, NCCN assembled a work group consisting of thought leaders from NCCN Member Institutions and other organizations, to provide guidance regarding the challenges health care providers and other key stakeholders face in incorporating biosimilars in health care practice. The work group identified challenges surrounding biosimilars, including health care provider knowledge, substitution practices, pharmacovigilance, naming and product tracking, coverage and reimbursement, use in off-label settings, and data requirements for approval.
Susan Charnley; Pamela Jakes; John Schelhas
2012-01-01
The American Recovery and Reinvestment Act of 2009 (the Recovery Act) aimed to create jobs and promote economic growth while addressing the Nationâs social and environmental needs. The USDA Forest Service received $1.15 billion in economic recovery funding. This report contains key findings and lessons learned from a socioeconomic assessment of Forest Service Recovery...
Kennedy, Jae; Wood, Elizabeth Geneva; Frieden, Lex
2017-01-01
The objective of this study was to assess trends in health insurance coverage, health service utilization, and health care access among working-age adults with and without disabilities before and after full implementation of the Affordable Care Act (ACA), and to identify current disability-based disparities following full implementation of the ACA. The ACA was expected to have a disproportionate impact on working-age adults with disabilities, because of their high health care usage as well as their previously limited insurance options. However, most published research on this population does not systematically look at effects before and after full implementation of the ACA. As the US Congress considers new health policy reforms, current and accurate data on this vulnerable population are essential. Weighted estimates, trend analyses and analytic models were conducted using the 1998-2016 National Health Interview Surveys (NHIS) and the 2014 Medical Expenditure Panel Survey. Compared with working-age adults without disabilities, those with disabilities are less likely to work, more likely to earn below the federal poverty level, and more likely to use public insurance. Average health costs for this population are 3 to 7 times higher, and access problems are far more common. Repeal of key features of the ACA, like Medicaid expansion and marketplace subsidies, would likely diminish health care access for working-age adults with disabilities.
40 CFR 63.1176 - Where can I find definitions of key words used in this subpart?
Code of Federal Regulations, 2010 CFR
2010-07-01
... words used in this subpart? 63.1176 Section 63.1176 Protection of Environment ENVIRONMENTAL PROTECTION... Production § 63.1176 Where can I find definitions of key words used in this subpart? The definitions of key words used in this subpart are in the Clean Air Act (Act), in § 63.2 of the general provisions in...
Kutscher, Beth; Landen, Rachel; Zigmond, Jessica
2013-04-08
At a time when a national conversation is focused on the gender imbalance atop most professions, healthcare can boast of having women in some of the most important policy and executive positions. Those honored in ourTop 25 Women in Healthcare program have a few lessons to share. "Be willing to take the job that everyone else isn't migrating to and make it work for you," says Marilyn Tavenner, acting CMS administrator.
Nurses take center stage in private duty home care.
Brackett, Nicole
2013-06-01
The Affordable Care Act gives America's largest group of health care providers--nurses--a unique chance to lead in improving outcomes, increasing patient satisfaction, and lowering costs. Nurses' roles continue to grow in settings from hospitals and long-term care facilities to home health and hospice agencies. Nurses are also key players in private duty home care, where they serve as care coordinators for clients. Working directly with doctors, therapists, in-home caregivers, and families, nurses are critical in delivering quality, seamless in-home care.
Satellite-Relayed Intercontinental Quantum Network.
Liao, Sheng-Kai; Cai, Wen-Qi; Handsteiner, Johannes; Liu, Bo; Yin, Juan; Zhang, Liang; Rauch, Dominik; Fink, Matthias; Ren, Ji-Gang; Liu, Wei-Yue; Li, Yang; Shen, Qi; Cao, Yuan; Li, Feng-Zhi; Wang, Jian-Feng; Huang, Yong-Mei; Deng, Lei; Xi, Tao; Ma, Lu; Hu, Tai; Li, Li; Liu, Nai-Le; Koidl, Franz; Wang, Peiyuan; Chen, Yu-Ao; Wang, Xiang-Bin; Steindorfer, Michael; Kirchner, Georg; Lu, Chao-Yang; Shu, Rong; Ursin, Rupert; Scheidl, Thomas; Peng, Cheng-Zhi; Wang, Jian-Yu; Zeilinger, Anton; Pan, Jian-Wei
2018-01-19
We perform decoy-state quantum key distribution between a low-Earth-orbit satellite and multiple ground stations located in Xinglong, Nanshan, and Graz, which establish satellite-to-ground secure keys with ∼kHz rate per passage of the satellite Micius over a ground station. The satellite thus establishes a secure key between itself and, say, Xinglong, and another key between itself and, say, Graz. Then, upon request from the ground command, Micius acts as a trusted relay. It performs bitwise exclusive or operations between the two keys and relays the result to one of the ground stations. That way, a secret key is created between China and Europe at locations separated by 7600 km on Earth. These keys are then used for intercontinental quantum-secured communication. This was, on the one hand, the transmission of images in a one-time pad configuration from China to Austria as well as from Austria to China. Also, a video conference was performed between the Austrian Academy of Sciences and the Chinese Academy of Sciences, which also included a 280 km optical ground connection between Xinglong and Beijing. Our work clearly confirms the Micius satellite as a robust platform for quantum key distribution with different ground stations on Earth, and points towards an efficient solution for an ultralong-distance global quantum network.
Satellite-Relayed Intercontinental Quantum Network
NASA Astrophysics Data System (ADS)
Liao, Sheng-Kai; Cai, Wen-Qi; Handsteiner, Johannes; Liu, Bo; Yin, Juan; Zhang, Liang; Rauch, Dominik; Fink, Matthias; Ren, Ji-Gang; Liu, Wei-Yue; Li, Yang; Shen, Qi; Cao, Yuan; Li, Feng-Zhi; Wang, Jian-Feng; Huang, Yong-Mei; Deng, Lei; Xi, Tao; Ma, Lu; Hu, Tai; Li, Li; Liu, Nai-Le; Koidl, Franz; Wang, Peiyuan; Chen, Yu-Ao; Wang, Xiang-Bin; Steindorfer, Michael; Kirchner, Georg; Lu, Chao-Yang; Shu, Rong; Ursin, Rupert; Scheidl, Thomas; Peng, Cheng-Zhi; Wang, Jian-Yu; Zeilinger, Anton; Pan, Jian-Wei
2018-01-01
We perform decoy-state quantum key distribution between a low-Earth-orbit satellite and multiple ground stations located in Xinglong, Nanshan, and Graz, which establish satellite-to-ground secure keys with ˜kHz rate per passage of the satellite Micius over a ground station. The satellite thus establishes a secure key between itself and, say, Xinglong, and another key between itself and, say, Graz. Then, upon request from the ground command, Micius acts as a trusted relay. It performs bitwise exclusive or operations between the two keys and relays the result to one of the ground stations. That way, a secret key is created between China and Europe at locations separated by 7600 km on Earth. These keys are then used for intercontinental quantum-secured communication. This was, on the one hand, the transmission of images in a one-time pad configuration from China to Austria as well as from Austria to China. Also, a video conference was performed between the Austrian Academy of Sciences and the Chinese Academy of Sciences, which also included a 280 km optical ground connection between Xinglong and Beijing. Our work clearly confirms the Micius satellite as a robust platform for quantum key distribution with different ground stations on Earth, and points towards an efficient solution for an ultralong-distance global quantum network.
Inspector General Semiannual Report to Congress - October 1, 2008 - March 31, 2009
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
2008-10-01
On behalf of the Department of Energy's Office of Inspector General, I am pleased to submit our Semiannual Report to Congress for the period ending March 31, 2009. The Report highlights key accomplishments of the Office of Inspector General, particularly pertaining to our efforts to ensure the economy, efficiency, and effectiveness of Department of Energy operations. Details pertaining to some of our most significant reviews and projects are presented in the Report. This reporting period has been quite eventful. On February 17, 2009, the President signed the American Recovery and Reinvestment Act of 2009. The stated intent of this newmore » legislation is to strengthen the U.S. economy through the creation of new jobs, aiding State and local governments with budget shortfalls, cutting taxes for working families, and investing in the long-term health of the Nation's economic prosperity. The Recovery Act establishes the status of the Nation's energy supply as a prime focus. Specifically, the Department of Energy will receive approximately $40 billion for various energy, environmental, and science programs and initiatives. The passage of this legislation makes the coming months an exciting and transformative time for the Department of Energy and the Office of Inspector General. In recognition of the need for effective oversight to protect taxpayer interests, the Recovery Act includes the creation of the Recovery Act Accountability and Transparency Board and mandates specific actions by the Inspectors General. I will be a permanent member of this newly created Board, along with nine other Inspectors General whose agencies are significant recipients of Recovery Act funds. Since the passage of the legislation, my office has developed a strategy consistent with the objectives outlined in the Recovery Act. The overarching goal of the strategy is to ensure that the taxpayers interests relating to the performance and results of the Recovery Act are protected. During this reporting period, my office issued two reports pertaining to the Recovery Act. In our first report entitled, 'The American Recovery and Reinvestment Act at the Department of Energy', we identified 'lessons learned' based on prior work with the intention of providing the Department with a resource as it moves forward with its Recovery Act-related efforts. Secondly, we recently issued a report entitled, 'The Department of Energy's Acquisition Workforce and its Impact on Implementation of the American Recovery and Reinvestment Act of 2009', which describes the current status of the Department's acquisition workforce, positive actions that have already been taken, and the challenges that remain in light of the impact of the Recovery Act. Additionally, although not initiated as a Recovery Act report, shortly after the passage of the legislation, we issued a related report entitled, 'The Department of Energy's Loan Guarantee Program for Innovative Energy Technologies', in which we evaluated the Department's progress in establishing internal and operational controls over the program. Further, we have conducted nearly 40 fraud awareness briefings to nearly 2,000 Department and contractor officials. While such briefings are a routine part of our work, these particular briefings were specifically designed to heighten awareness of the vulnerabilities, risks, and potential fraud schemes related to the Recovery Act. The work of safeguarding public resources and the public trust is a collaborative effort that stretches across government, including agency management and the Congress. Much work has been done, but more remains and we look forward to the coming challenges.« less
Grison, Claire M.; Miles, Jennifer A.; Robin, Sylvie
2016-01-01
Abstract A major current challenge in bioorganic chemistry is the identification of effective mimics of protein secondary structures that act as inhibitors of protein–protein interactions (PPIs). In this work, trans‐2‐aminocyclobutanecarboxylic acid (tACBC) was used as the key β‐amino acid component in the design of α/β/γ‐peptides to structurally mimic a native α‐helix. Suitably functionalized α/β/γ‐peptides assume an α‐helix‐mimicking 12,13‐helix conformation in solution, exhibit enhanced proteolytic stability in comparison to the wild‐type α‐peptide parent sequence from which they are derived, and act as selective inhibitors of the p53/hDM2 interaction. PMID:27467859
Grison, Claire M; Miles, Jennifer A; Robin, Sylvie; Wilson, Andrew J; Aitken, David J
2016-09-05
A major current challenge in bioorganic chemistry is the identification of effective mimics of protein secondary structures that act as inhibitors of protein-protein interactions (PPIs). In this work, trans-2-aminocyclobutanecarboxylic acid (tACBC) was used as the key β-amino acid component in the design of α/β/γ-peptides to structurally mimic a native α-helix. Suitably functionalized α/β/γ-peptides assume an α-helix-mimicking 12,13-helix conformation in solution, exhibit enhanced proteolytic stability in comparison to the wild-type α-peptide parent sequence from which they are derived, and act as selective inhibitors of the p53/hDM2 interaction. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
Querstret, Dawn; Cropley, Mark; Fife-Schaw, Chris
2017-04-01
This study aimed to extend our theoretical understanding of how mindfulness-based interventions exert their positive influence on measures of occupational health. Employing a randomized waitlist control study design, we sought to (a) assess an Internet-based instructor-led mindfulness intervention for its effect on key factors associated with "recovery from work," specifically, work-related rumination, fatigue, and sleep quality; (b) assess different facets of mindfulness (acting with awareness, describing, nonjudging, and nonreacting) as mechanisms of change; and (c) assess whether the effect of the intervention was maintained over time by following up our participants after 3 and 6 months. Participants who completed the mindfulness intervention (n = 60) reported significantly lower levels of work-related rumination and fatigue, and significantly higher levels of sleep quality, when compared with waitlist control participants (n = 58). Effects of the intervention were maintained at 3- and 6-month follow-up with medium to large effect sizes. The effect of the intervention was primarily explained by increased levels of only 1 facet of mindfulness (acting with awareness). This study provides support for online mindfulness interventions to aid recovery from work and furthers our understanding with regard to how mindfulness interventions exert their positive effects. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hebdon, J.; Yerxa, J.; Romine, L.
The Hanford Nuclear Reservation is a former U. S. Department of Energy Defense Production Site. The site is currently listed on the National Priorities List of the Comprehensive Environmental Response Compensation and Liability Act of 1980 (CERCLA) and is undergoing cleanup and environmental restoration. The PFP is a former Plutonium metal production facility. The operating mission of the PFP ended with a DOE Headquarters shutdown letter in October of 1996. Generally, the receipt of a shutdown letter initiates the start of Transition (as the first step of Decommissioning) of a facility. The Hanford site is subject to the Hanford Federalmore » Facilities Compliance Act and Consent Order (HFFCCO), an order on consent signed by the DOE, the U. S. Environmental Protection Agency, (EPA) and the Washington Department of Ecology (WDOE). Under the HFFCCO, negotiations for transition milestones begin within six months after the issuance of a shutdown order. In the case of the PFP, the Nuclear Materials disposition and stabilization activities, a DOE responsibility, were necessary as precursor activities to Transition. This situation precipitated a crisis in the negotiations between the agencies, and formal negotiations initiated in 1997 ended in failure. The negotiations reached impasse on several key regulatory and operational issues. The 1997 negotiation was characterized by a strongly positional style. DOE and the regulatory personnel took hard lines early in the negotiations and were unable to move to resolution of key issues after a year and a half. This resulted in unhappy stakeholders, poor publicity and work delays as well as wounded relationships between DOE and the regulatory community. In the 2000-2001 PFP negotiations, a completely different approach was suggested and eventually initiated: Collaborative Negotiations. The collaborative negotiation style resulted in agreement between the agencies on all key issues within 6 months of initiation. All parties were very pleased with the results and all parties were relieved that protracted negotiations sessions were not needed with the new style of working together collaboratively to serve each other's interests. The characteristics of collaborative negotiations included building trust, emphasizing equality of team members, problem solving by the entire team, relying on individual communications and self-management skills. The team found that trust building sessions were key to successfully working through issues. Relationship differences were too often ignored in the past negotiations and were recognized and worked through in the collaborative process.« less
Kennedy, Jae; Wood, Elizabeth Geneva; Frieden, Lex
2017-01-01
The objective of this study was to assess trends in health insurance coverage, health service utilization, and health care access among working-age adults with and without disabilities before and after full implementation of the Affordable Care Act (ACA), and to identify current disability-based disparities following full implementation of the ACA. The ACA was expected to have a disproportionate impact on working-age adults with disabilities, because of their high health care usage as well as their previously limited insurance options. However, most published research on this population does not systematically look at effects before and after full implementation of the ACA. As the US Congress considers new health policy reforms, current and accurate data on this vulnerable population are essential. Weighted estimates, trend analyses and analytic models were conducted using the 1998-2016 National Health Interview Surveys (NHIS) and the 2014 Medical Expenditure Panel Survey. Compared with working-age adults without disabilities, those with disabilities are less likely to work, more likely to earn below the federal poverty level, and more likely to use public insurance. Average health costs for this population are 3 to 7 times higher, and access problems are far more common. Repeal of key features of the ACA, like Medicaid expansion and marketplace subsidies, would likely diminish health care access for working-age adults with disabilities. PMID:29166812
Prediction of interface residue based on the features of residue interaction network.
Jiao, Xiong; Ranganathan, Shoba
2017-11-07
Protein-protein interaction plays a crucial role in the cellular biological processes. Interface prediction can improve our understanding of the molecular mechanisms of the related processes and functions. In this work, we propose a classification method to recognize the interface residue based on the features of a weighted residue interaction network. The random forest algorithm is used for the prediction and 16 network parameters and the B-factor are acting as the element of the input feature vector. Compared with other similar work, the method is feasible and effective. The relative importance of these features also be analyzed to identify the key feature for the prediction. Some biological meaning of the important feature is explained. The results of this work can be used for the related work about the structure-function relationship analysis via a residue interaction network model. Copyright © 2017 Elsevier Ltd. All rights reserved.
29 CFR 825.219 - Rights of a key employee.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... FMLA leave (or when FMLA leave commences, if earlier) that he or she qualifies as a key employee. At...
29 CFR 825.219 - Rights of a key employee.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... FMLA leave (or when FMLA leave commences, if earlier) that he or she qualifies as a key employee. At...
29 CFR 825.219 - Rights of a key employee.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... FMLA leave (or when FMLA leave commences, if earlier) that he or she qualifies as a key employee. At...
29 CFR 825.219 - Rights of a key employee.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825... FMLA leave (or when FMLA leave commences, if earlier) that he or she qualifies as a key employee. At...
29 CFR 825.217 - Key employee, general rule.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Key employee, general rule. 825.217 Section 825.217 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825...
76 FR 19524 - Privacy Act of 1974; Deletion of System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-07
... Affairs (VA) is deleting a system of records entitled ``PROS/KEYS User Permissions Database-VA'' (67VA30... requirement for VA to maintain this system of records no longer exists because the PROS/ KEYS Database was... DEPARTMENT OF VETERANS AFFAIRS Privacy Act of 1974; Deletion of System of Records AGENCY...
Viroid Pathogenicity: One Process, Many Faces
Owens, Robert A.; Hammond, Rosemarie W.
2009-01-01
Despite the non-coding nature of their small RNA genomes, the visible symptoms of viroid infection resemble those associated with many plant virus diseases. Recent evidence indicates that viroid-derived small RNAs acting through host RNA silencing pathways play a key role in viroid pathogenicity. Host responses to viroid infection are complex, involving signaling cascades containing host-encoded protein kinases and crosstalk between hormonal and defense-signaling pathways. Studies of viroid-host interaction in the context of entire biochemical or developmental pathways are just beginning, and many working hypotheses have yet to be critically tested. PMID:21994551
The Mental Capacity Act 1: advance decisions.
Lynch, Teresa
This is the first of a two-part unit on the Mental Capacity Act 2005. Part 1 outlines the act's key principles and implications. Healthcare professionals' responsibilities are examined in relation to advance decisions.
Thermal diode utilizing asymmetric contacts to heat baths.
Komatsu, Teruhisa S; Ito, Nobuyasu
2010-01-01
We propose a simple thermal diode passively acting as a rectifier of heat current. The key design of the diode is the size asymmetry of the areas in contact with two distinct heat baths. The heat-conducting medium is liquid, inside of which gaslike regions are induced depending on the applied conditions. Simulating nanoscale systems of this diode, the rectification of heat current is demonstrated. If the packing density of the medium and the working regime of temperature are properly chosen, the heat current is effectively cut off when the heat bath with narrow contact is hotter, but it flows normally under opposite temperature conditions. In the former case, the gaslike region is induced in the system and it acts as a thermal insulator because it covers the entire narrow area of contact with the bath.
29 CFR 825.219 - Rights of a key employee.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Rights of a key employee. 825.219 Section 825.219 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee Leave Entitlements Under the Family and Medical Leave Act § 825...
25 CFR 309.2 - What are the key definitions for purposes of the Act?
Code of Federal Regulations, 2010 CFR
2010-04-01
....2 Section 309.2 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR PROTECTION OF INDIAN ARTS AND CRAFTS PRODUCTS § 309.2 What are the key definitions for purposes of the Act? (a) Indian...-member Indian artisan. (c) Indian arts and crafts organization means any legally established arts and...
Secret handshakes: cell-cell interactions and cellular mimics.
Cohen, Daniel J; Nelson, W James
2018-02-01
Cell-cell junctions, acting as 'secret handshakes', mediate cell-cell interactions and make multicellularity possible. Work over the previous century illuminated key players comprising these junctions including the cadherin superfamily, nectins, CAMs, connexins, notch/delta, lectins, and eph/Ephrins. Recent work has focused on elucidating how interactions between these complex and often contradictory cues can ultimately give rise to large-scale organization in tissues. This effort, in turn, has enabled bioengineering advances such as cell-mimetic interfaces that allow us to better probe junction biology and to develop new biomaterials. This review details exciting, recent developments in these areas as well as providing both historical context and a discussion of some topical challenges and opportunities for the future. Copyright © 2018 Elsevier Ltd. All rights reserved.
ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR
Larcombe, L.; Hendricusdottir, R.; Attwood, T.K.; Bacall, F.; Beard, N.; Bellis, L.J.; Dunn, W.B.; Hancock, J.M.; Nenadic, A.; Orengo, C.; Overduin, B.; Sansone, S-A; Thurston, M.; Viant, M.R.; Winder, C.L.; Goble, C.A.; Ponting, C.P.; Rustici, G.
2017-01-01
ELIXIR-UK is the UK node of ELIXIR, the European infrastructure for life science data. Since its foundation in 2014, ELIXIR-UK has played a leading role in training both within the UK and in the ELIXIR Training Platform, which coordinates and delivers training across all ELIXIR members. ELIXIR-UK contributes to the Training Platform’s coordination and supports the development of training to address key skill gaps amongst UK scientists. As part of this work it acts as a conduit for nationally-important bioinformatics training resources to promote their activities to the ELIXIR community. ELIXIR-UK also leads ELIXIR’s flagship Training Portal, TeSS, which collects information about a diverse range of training and makes it easily accessible to the community. ELIXIR-UK also works with others to provide key digital skills training, partnering with the Software Sustainability Institute to provide Software Carpentry training to the ELIXIR community and to establish the Data Carpentry initiative, and taking a lead role amongst national stakeholders to deliver the StaTS project – a coordinated effort to drive engagement with training in statistics. PMID:28781748
Pereyra, Francisca; Micha, Ariela
2016-01-01
The article explores two key factors which contribute to shape the poor working conditions of nursing in Argentina. A first objective focuses on exploring the effect of the occupation's care component, closely associated with cultural images of "inherent" female qualities, on working conditions. A second objective aims to examine the way in which the organization of health services provision in Argentina intensifies the vulnerability of this occupation. Regarding the methodology, the fieldwork conducted in the Metropolitan Area of Buenos Aires included in-depth interviews with key informants and group interviews with nurses. Among the results, on the one hand it is shown how the social devaluation of care is reflected in the discourse of those who perform the occupation as well as in institutional practices and policies in the health sector. On the other hand, it is shown that the decentralization and fragmentation of the health system act as additional obstacles hampering the articulation of labor demands.
ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR.
Larcombe, L; Hendricusdottir, R; Attwood, T K; Bacall, F; Beard, N; Bellis, L J; Dunn, W B; Hancock, J M; Nenadic, A; Orengo, C; Overduin, B; Sansone, S-A; Thurston, M; Viant, M R; Winder, C L; Goble, C A; Ponting, C P; Rustici, G
2017-01-01
ELIXIR-UK is the UK node of ELIXIR, the European infrastructure for life science data. Since its foundation in 2014, ELIXIR-UK has played a leading role in training both within the UK and in the ELIXIR Training Platform, which coordinates and delivers training across all ELIXIR members. ELIXIR-UK contributes to the Training Platform's coordination and supports the development of training to address key skill gaps amongst UK scientists. As part of this work it acts as a conduit for nationally-important bioinformatics training resources to promote their activities to the ELIXIR community. ELIXIR-UK also leads ELIXIR's flagship Training Portal, TeSS, which collects information about a diverse range of training and makes it easily accessible to the community. ELIXIR-UK also works with others to provide key digital skills training, partnering with the Software Sustainability Institute to provide Software Carpentry training to the ELIXIR community and to establish the Data Carpentry initiative, and taking a lead role amongst national stakeholders to deliver the StaTS project - a coordinated effort to drive engagement with training in statistics.
48 CFR 22.403-4 - Department of Labor regulations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... under the Davis-Bacon Act, Contract Work Hours and Safety Standards Act, Copeland (Anti-Kickback) Act... Division, or administrative law judges under the Davis-Bacon Act, Contract Work Hours and Safety Standards... of weekly payroll records; (3) Part 5, relating to enforcement of the Davis-Bacon Act, Contract Work...
Advanced Communications Technology Satellite (ACTS): Four-Year System Performance
NASA Technical Reports Server (NTRS)
Acosta, Roberto J.; Bauer, Robert; Krawczyk, Richard J.; Reinhart, Richard C.; Zernic, Michael J.; Gargione, Frank
1999-01-01
The Advanced Communications Technology Satellite (ACTS) was conceived at the National Aeronautics and Space Administration (NASA) in the late 1970's as a follow-on program to ATS and CTS to continue NASA's long history of satellite communications projects. The ACTS project set the stage for the C-band satellites that started the industry, and later the ACTS project established the use of Ku-band for video distribution and direct-to-home broadcasting. ACTS, launched in September 1993 from the space shuttle, created a revolution in satellite system architecture by using digital communications techniques employing key technologies such as a fast hopping multibeam antenna, an on-board baseband processor, a wide-band microwave switch matrix, adaptive rain fade compensation, and the use of 900 MHz transponders operating at Ka-band frequencies. This paper describes the lessons learned in each of the key ACTS technology areas, as well as in the propagation investigations.
Mental capacity Act 2005: assessing decision-making capacity.
Griffith, Richard; Tengnah, Cassam
2008-06-01
In last month's article on the Mental Capacity Act 2005 Richard Griffith and Cassam Tengnah outlined the statutory principles and key powers that underpin the Act. This month's article considers one of the fundamental requirements of the Mental Capacity Act 2005, how and when should district nurses assess decision making capacity.
Acceptance and Commitment Therapy (ACT): An Overview for Practitioners
ERIC Educational Resources Information Center
Bowden, Tim; Bowden, Sandra
2012-01-01
Acceptance and Commitment Therapy (ACT) offers school counsellors a practical and meaningful approach to helping students deal with a range of issues. This is achieved through encouraging psychological flexibility through the application of six key principles. This article describes our introduction to ACT, ACT's application to children and…
NASA Astrophysics Data System (ADS)
Chen, Zhibin; Xiao, Cheng; Xiao, Wenjian; Qin, Mengze; Liu, Xianhong
2016-01-01
To prevent tragic disasters caused by terror acts and warfare threats, security check personnel must be capable of discovering, distinguishing and eliminating the explosives at multiple circumstances. Standoff technology for the remote detection of explosives and their traces on contaminated surfaces is a research field that has become a heightened priority in recent years for homeland security and counter-terrorism applications. There has been a huge increase in research within this area, the improvement of standoff trace explosives detection by optical-related technology. This paper provides a consolidation of information relating to recent advances in several key problems of, without being limited to one specific research area or explosive type. Working laser wavelength of detection system is discussed. Generation and collection of explosives spectra signal are summarized. Techniques for analysing explosives spectra signal are summed up.
Mao, Gen-Hong; Feng, Zonggang; He, Yan; Huang, Yu-Rong
2014-02-24
The aim was to compare the efficacy of long-acting and short-acting gonadotropin-releasing hormone (GnRH) agonists by long protocol on embryo quality, endometrial thickness and pregnancy rate in in vitro fertilization. In this retrospective study, long-term pituitary downregulation, achieved with long- and short-acting GnRH agonists (GnRHa), was performed for patients undergoing in vitro fertilization (n = 175). There were no significant differences between the long and short-acting GnRH group (63.16% vs. 66.26%, p > 0.05), and the secondary and primary infertility group (63.47% vs. 66.86%, p > 0.05) in embryo quality. Logistic regression analysis showed that type of infertility and endometrial thickness were significantly associated with pregnancy outcome. Patients in the long-acting GnRHa group had a thicker endometrium on the day of human chorionic gonadotrophin (hCG) administration (10.79 ±2.62 mm vs. 9.64 ±1.97 mm, p < 0.01), lower serum luteinizing hormone (LH) concentration (1.21 ±1.13 vs. 2.53 ±3.39) and a higher pregnancy rate (59.60% vs. 43.42%, p < 0.05) than those of patients in the short-acting GnRHa group. This work suggests that types of agonist protocol and infertility may not affect embryo quality. Type of infertility and endometrial thickness may be positive predictors for clinical pregnancy, but the key finding is that the long-acting GnRHa protocol may be an effective method of improving endometrial thickness, endometrial receptivity and pregnancy rate in in vitro fertilization.
Code of Federal Regulations, 2010 CFR
2010-07-01
... the Contract Work Hours and Safety Standards Act. 5.15 Section 5.15 Labor Office of the Secretary of... WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and Procedures § 5.15 Limitations, variations, tolerances, and exemptions under the Contract Work Hours and Safety Standards Act. (a...
ERIC Educational Resources Information Center
Grey, Anne C.
2010-01-01
From bipartisan origins and a laudable intent, the No Child Left Behind (Act) of 2001 has profoundly altered the condition of art education. A historical vantage point and review of literature reveals the current status of pending arts language revisions to the NCLB Act, as well as a pressing need to examine the key recommendations and to consider…
Hydrogen enhances strength and ductility of an equiatomic high-entropy alloy.
Luo, Hong; Li, Zhiming; Raabe, Dierk
2017-08-29
Metals are key materials for modern manufacturing and infrastructures as well as transpot and energy solutions owing to their strength and formability. These properties can severely deteriorate when they contain hydrogen, leading to unpredictable failure, an effect called hydrogen embrittlement. Here we report that hydrogen in an equiatomic CoCrFeMnNi high-entropy alloy (HEA) leads not to catastrophic weakening, but instead increases both, its strength and ductility. While HEAs originally aimed at entropy-driven phase stabilization, hydrogen blending acts opposite as it reduces phase stability. This effect, quantified by the alloy's stacking fault energy, enables nanotwinning which increases the material's work-hardening. These results turn a bane into a boon: hydrogen does not generally act as a harmful impurity, but can be utilized for tuning beneficial hardening mechanisms. This opens new pathways for the design of strong, ductile, and hydrogen tolerant materials.
The role of culture in health literacy and chronic disease screening and management.
Shaw, Susan J; Huebner, Cristina; Armin, Julie; Orzech, Kathryn; Orzech, Katherine; Vivian, James
2009-12-01
Cultural and language differences and socioeconomic status interact with and contribute to low health literacy, defined as the inability to understand or act on medical/therapeutic instructions. Health literacy is increasingly recognized as an important factor in patient compliance, cancer screening utilization, and chronic disease outcomes. Commendable efforts have been initiated by the American Medical Association and other organizations to address low health literacy among patients. Less work has been done, however, to place health literacy in the broader context of socioeconomic and cultural differences among patients and providers that hinder communication and compliance. This review examines cultural influences on health literacy, cancer screening and chronic disease outcomes. We argue that cultural beliefs around health and illness contribute to an individual's ability to understand and act on a health care provider's instructions. This paper proposes key aspects of the intersection between health literacy and culturally varying beliefs about health which merit further exploration.
Lexén, Annika; Svensson, Bengt
2016-08-01
Despite the lack of evidence for effectiveness of the Flexible Assertive Community Treatment (Flexible ACT), the model is considered feasible and is well received by mental health professionals. No current studies have adequately examined mental health professional experiences of working with Flexible ACT. The aim of this study was to explore mental health professional experiences of working with the Flexible ACT model compared with standard care. The study was guided by grounded theory and based on the interviews with 19 theoretically chosen mental health professionals in Swedish urban areas primarily working with consumers with psychosis, who had worked with the Flexible ACT model for at least 6 months. The analysis resulted in the core category: "Flexible ACT and the shared caseload create a common action space" and three main categories: (1) "Flexible ACT fills the need for a systematic approach to crisis intervention"; (2) "Flexible ACT has advantages in the psychosocial working environment"; and (3) "Flexible ACT increases the quality of care". Mental health professionals may benefit from working with the Flexible ACT model through decreased job-strain and stress, increased feeling of being in control over their work situation, and experiences of providing higher quality of care.
Divergent strategy for the synthesis of alpha-aryl-substituted fosmidomycin analogues.
Devreux, Vincent; Wiesner, Jochen; Jomaa, Hassan; Rozenski, Jef; Van der Eycken, Johan; Van Calenbergh, Serge
2007-05-11
Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids. This work describes a divergent strategy for the synthesis of a series of alpha-aryl-substituted fosmidomycin analogues, featuring a palladium-catalyzed Stille coupling as the key step. An alpha-(4-cyanophenyl)fosmidomycin analogue emerged as the most potent analogue in the present series. Its antimalarial activity clearly surpasses that of the reference compound fosmidomycin.
Hayes, Steven C.; Levin, Michael E.; Plumb-Vilardaga, Jennifer; Villatte, Jennifer L.; Pistorello, Jacqueline
2012-01-01
A number of recent authors have compared acceptance and commitment therapy (ACT) and traditional cognitive behavior therapy (CBT). The present article describes ACT as a distinct and unified model of behavior change, linked to a specific strategy of scientific development, which we term “contextual behavioral science.” We outline the empirical progress of ACT and describe its distinctive development strategy. A contextual behavioral science approach is an inductive attempt to build more adequate psychological systems based on philosophical clarity; the development of basic principles and theories; the development of applied theories linked to basic ones; techniques and components linked to these processes and principles; measurement of theoretically key processes; an emphasis on mediation and moderation in the analysis of applied impact; an interest in effectiveness, dissemination, and training; empirical testing of the research program across a broad range of areas and levels of analysis; and the creation of a more effective scientific and clinical community. We argue that this is a reasonable approach, focused on long-term progress, and that in broad terms it seems to be working. ACT is not hostile to traditional CBT, and is not directly buoyed by whatever weaknesses traditional CBT may have. ACT should be measured at least in part against its own goals as specified by its own developmental strategy. PMID:23611068
Hayes, Steven C; Levin, Michael E; Plumb-Vilardaga, Jennifer; Villatte, Jennifer L; Pistorello, Jacqueline
2013-06-01
A number of recent authors have compared acceptance and commitment therapy (ACT) and traditional cognitive behavior therapy (CBT). The present article describes ACT as a distinct and unified model of behavior change, linked to a specific strategy of scientific development, which we term "contextual behavioral science." We outline the empirical progress of ACT and describe its distinctive development strategy. A contextual behavioral science approach is an inductive attempt to build more adequate psychological systems based on philosophical clarity; the development of basic principles and theories; the development of applied theories linked to basic ones; techniques and components linked to these processes and principles; measurement of theoretically key processes; an emphasis on mediation and moderation in the analysis of applied impact; an interest in effectiveness, dissemination, and training; empirical testing of the research program across a broad range of areas and levels of analysis; and the creation of a more effective scientific and clinical community. We argue that this is a reasonable approach, focused on long-term progress, and that in broad terms it seems to be working. ACT is not hostile to traditional CBT, and is not directly buoyed by whatever weaknesses traditional CBT may have. ACT should be measured at least in part against its own goals as specified by its own developmental strategy. Copyright © 2011. Published by Elsevier Ltd.
Ramifications of the Family and Medical Leave Act of 1993.
Luecke, R W; Wise, R J; List, M S
1993-08-01
Six months ago, the Family and Medical Leave Act of 1993 was signed into law, and key provisions of the act became effective on August 5, 1993. This article examines the main provisions of the act, explains how employee leaves will be granted in compliance with the act, outlines the consequences of noncompliance with the act, analyzes the operational ramifications of the act, quantifies the financial implications of the act, and discusses the role of the healthcare financial manager in assisting with the formulation of a hospital policy to comply with the act.
The Great Balancing Act: Financial Equity and Local Control. Can Vermont's Act 60 Do It?
ERIC Educational Resources Information Center
Jimerson, Lorna
Vermont's Equal Educational Opportunity Act of 1997 (Act 60) has attracted attention because of its funding and quality components, and the highly publicized responses to its implementation. A key feature is its "recapture" provision in which property-wealthy towns contribute to a state educational fund that helps support education in…
Jean-Anthelme Brillat-Savarin's 1825 treatise on the mouth and ingestion.
Chong, Gabriel Tse Feng
2012-12-01
This article quotes and discusses Jean-Anthelme Brillat-Savarin's musings on the mouth and ingestion as described in his book The Physiology of Taste. The book was first published in France in December 1825, and is still widely read as a key work in Gastronomy today. The mouth is intimately related to the acts of chewing, swallowing and eating and it would be interesting to report an early 19th century epicurean's views on the mouth. Passages from Brillat-Savarin's book describing the functions of the teeth and tongue and the acts of tasting, chewing, and swallowing are quoted in full. Anecdotes also include one on the horrifying punishment of having one's tongue removed and another illustrating the poor oral health found among Europeans of that era. His work offers a unique glimpse into how a 19th century gastronome viewed the oral cavity and its gastronomical functions. While some of his writings may appear archaic and antediluvian to the modern reader; others relating to, for example chewing and swallowing, are surprisingly accurate by contemporary standards. Nonetheless, the gastronomic savant seemed to know a lot right about modern stomatology! Copyright © 2012. Published by Elsevier B.V.
45 CFR 2543.84 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Contract Work Hours and Safety Standards Act. 2543... laborer on the basis of a standard work week of 40 hours. Work in excess of the standard work week is... pay for all hours worked in excess of 40 hours in the work week. Section 107 of the Act is applicable...
The Family and Medical Leave Act--key provisions and potential problems.
Shaller, E H; Qualiana, M K
1993-01-01
The recently enacted Family and Medical Leave Act requires larger employers to provide eligible employees with up to twelve weeks of unpaid leave for certain medical and family-related reasons. This article addresses who the law applies to; the circumstances when leave must be granted; how the leave period is supposed to be scheduled; various notice, scheduling, medical certification, and reporting requirements; reinstatement and continuation-of-benefits requirements; and other key provisions of the Act. The basic requirements of the Act are not complicated, but certain issues that are not addressed by the Act or its legislative history--such as what qualifies as a serious health condition justifying a leave, when an intermittent or reduced schedule leave may be taken and how such schedules are determined, and how differences with state family and medical leave laws are to be reconciled--will have to be resolved by administrative regulation or litigation.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Standard Form 1093, Schedule of Withholdings Under the Davis-Bacon Act and/or the Contract Work Hours and Safety Standards Act... Withholdings Under the Davis-Bacon Act and/or the Contract Work Hours and Safety Standards Act. EC01MY91.076 ...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Standard Form 1093, Schedule of Withholdings Under the Davis-Bacon Act and/or the Contract Work Hours and Safety Standards Act... Withholdings Under the Davis-Bacon Act and/or the Contract Work Hours and Safety Standards Act. EC01MY91.076 ...
Code of Federal Regulations, 2011 CFR
2011-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... Act and under the Contract Work Hours and Safety Standards Act for contracts subject to the Service...
Code of Federal Regulations, 2010 CFR
2010-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... Act and under the Contract Work Hours and Safety Standards Act for contracts subject to the Service...
2018-01-01
Mineworkers are continually introduced to protective technologies on the job. Yet, their perceptions toward the technologies are often not addressed until they are actively trying to use them, which may halt safe technology adoption and associated work practices. This study explored management and worker perspectives toward three technologies to forecast adoption and behavioral intention on the job. Interviews and focus groups were conducted with 21 mineworkers and 19 mine managers to determine the adoption process stage algorithm for workers and managers, including perceived barriers to using new safety and health technologies. Differences between workers and managers were revealed in terms of readiness, perceptions, and initial trust in using technologies. Workers, whether they had or had not used a particular technology, still had negative perceptions toward its use in the initial introduction and integration at their mine site, indicating a lengthy time period needed for full adoption. The key finding from these results is that a carefully considered and extended introduction of technology for workers in Stage 3 (undecided to act) is most important to promote progression to Stage 5 (decided to act) and to avoid Stage 4 (decided not to act). In response, organizational management may need to account for workers’ particular stage algorithm, using the Precaution Adoption Process Model, to understand how to tailor messages about protective technologies, administer skill-based trainings and interventions that raise awareness and knowledge, and ultimately encourage safe adoption of associated work practices. PMID:29862314
Haas, Emily J
2018-03-01
Mineworkers are continually introduced to protective technologies on the job. Yet, their perceptions toward the technologies are often not addressed until they are actively trying to use them, which may halt safe technology adoption and associated work practices. This study explored management and worker perspectives toward three technologies to forecast adoption and behavioral intention on the job. Interviews and focus groups were conducted with 21 mineworkers and 19 mine managers to determine the adoption process stage algorithm for workers and managers, including perceived barriers to using new safety and health technologies. Differences between workers and managers were revealed in terms of readiness, perceptions, and initial trust in using technologies. Workers, whether they had or had not used a particular technology, still had negative perceptions toward its use in the initial introduction and integration at their mine site, indicating a lengthy time period needed for full adoption. The key finding from these results is that a carefully considered and extended introduction of technology for workers in Stage 3 (undecided to act) is most important to promote progression to Stage 5 (decided to act) and to avoid Stage 4 (decided not to act). In response, organizational management may need to account for workers' particular stage algorithm, using the Precaution Adoption Process Model, to understand how to tailor messages about protective technologies, administer skill-based trainings and interventions that raise awareness and knowledge, and ultimately encourage safe adoption of associated work practices.
Camalier, Corrie R; Wang, Alice Y; McIntosh, Lindsey G; Park, Sohee; Neimat, Joseph S
2017-03-01
Computational and theoretical accounts hypothesize the basal ganglia play a supramodal "gating" role in the maintenance of working memory representations, especially in preservation from distractor interference. There are currently two major limitations to this account. The first is that supporting experiments have focused exclusively on the visuospatial domain, leaving questions as to whether such "gating" is domain-specific. The second is that current evidence relies on correlational measures, as it is extremely difficult to causally and reversibly manipulate subcortical structures in humans. To address these shortcomings, we examined non-spatial, auditory working memory performance during reversible modulation of the basal ganglia, an approach afforded by deep brain stimulation of the subthalamic nucleus. We found that subthalamic nucleus stimulation impaired auditory working memory performance, specifically in the group tested in the presence of distractors, even though the distractors were predictable and completely irrelevant to the encoding of the task stimuli. This study provides key causal evidence that the basal ganglia act as a supramodal filter in working memory processes, further adding to our growing understanding of their role in cognition. Copyright © 2017 Elsevier Ltd. All rights reserved.
The consuming instinct. What Darwinian consumption reveals about human nature.
Saad, Gad
2013-01-01
Editor's note: In this engaging talk given last February on a particularly cold and blustery day at Texas Tech University, Professor Gad Saad of Concordia University discusses his work in the area of evolutionary consumption. In making the case for understanding consumerism from a Darwinian perspective, Saad addresses several key tenets from his books The Consuming Instinct (1) and The Evolutionary Bases of Consumption. (2) In particular, Saad argues that: (1) many consumption acts can be mapped onto four key Darwinian modules (survival, mating, kin selection, and reciprocal altruism); and, (2) cultural products such as song lyrics and movie plotlines are fossils of the human mind that highlight a shared, biologically based human nature. In this wide-ranging inquiry, Saad summarizes several of his other empirical works, including the effects of conspicuous consumption on men's testosterone levels (3) and how the ovulatory cycle in the human female influences consumption. (4) Overall, Professor Saad contends that an infusion of evolutionary and biologically based perspectives into the discipline of consumer behavior and related government regulatory policies yields myriad benefits, notably greater consilience, more effective practices, an ethos of interdisciplinarity, and methodological pluralism.
KEY COMPARISON: Final report on CCQM-K69 key comparison: Testosterone glucuronide in human urine
NASA Astrophysics Data System (ADS)
Liu, Fong-Ha; Mackay, Lindsey; Murby, John
2010-01-01
The CCQM-K69 key comparison of testosterone glucuronide in human urine was organized under the auspices of the CCQM Organic Analysis Working Group (OAWG). The National Measurement Institute Australia (NMIA) acted as the coordinating laboratory for the comparison. The samples distributed for the key comparison were prepared at NMIA with funding from the World Anti-Doping Agency (WADA). WADA granted the approval for this material to be used for the intercomparison provided the distribution and handling of the material were strictly controlled. Three national metrology institutes (NMIs)/designated institutes (DIs) developed reference methods and submitted data for the key comparison along with two other laboratories who participated in the parallel pilot study. A good selection of analytical methods and sample workup procedures was displayed in the results submitted considering the complexities of the matrix involved. The comparability of measurement results was successfully demonstrated by the participating NMIs. Only the key comparison data were used to estimate the key comparison reference value (KCRV), using the arithmetic mean approach. The reported expanded uncertainties for results ranged from 3.7% to 6.7% at the 95% level of confidence and all results agreed within the expanded uncertainty of the KCRV. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Goodyear, Helen M; Lakshminarayana, Indumathy; Wall, David; Bindal, Taruna
2014-09-01
To look at why a regional cohort of UK doctors chose a paediatric career and to ascertain views on their career near the end of training year one. A 20-item questionnaire was sent to all new regional paediatric specialty trainees. Three focus groups were held with trainees near the end of year one to elicit key themes. West Midlands Deanery, UK. Twenty-nine new regional paediatric specialty trainees in year one completed the questionnaire. A total of 15 trainees participated in the focus groups near the end of year one training. Reasons for choosing a paediatric career and factors which further influence career choice for trainees during their first specialty training year. Key influencing factors for choosing paediatrics were enjoying working with children and positive undergraduate experience of the specialty. All trainees had paediatrics as their first choice specialty and undertook a paediatric Foundation post. Near the end of year one, doubts were cast on career aspirations due to seeing middle grade colleagues struggling with work-life balance and a growing feeling that family came first. Senior trainees need to be aware that they act as powerful role models for their more junior colleagues and therefore have an influential role on how juniors perceive a paediatric career. Family friendly flexible working patterns in paediatrics are vital to retain junior trainees. All paediatric staff are role models and need to be enthusiastic, keen to teach and to promote a positive working environment.
Ward, Richard; Campbell, Sarah; Keady, John
2014-08-01
Appearance and the work invested in it by and for people with dementia are a neglected issue within dementia studies. In policy and practice there exists an assumption that the role of supporting a person to manage their appearance is easily assumed by another within caring encounters, only to be subsumed within the daily task-oriented provision of care. This paper reports on interviews conducted as part of the Hair and Care project, which explored questions of appearance and the meanings it holds with people with dementia. The research used 'appearance biographies', a method which allows for a range of topics to be considered about appearance throughout the life course, acting as a conduit for reminiscence and life story work. The paper reports on the key themes and findings from these interviews, discussing them in the context of a wider debate on dementia, self-expression and agency. A key question posed by the authors is whether appearance and the work invested in it are legitimate considerations for dementia care policy and practice. And if so, how should we make sense of this work and what significance should we attach to it? In seeking to answer these questions the authors position the perspectives and experiences of people with dementia as central to their analysis. A narrative framework is suggested as a useful basis on which to understand the work of managing appearance over the life course. The implications for policy and practice are outlined. Copyright © 2014 Elsevier Inc. All rights reserved.
48 CFR 22.406-9 - Withholding from or suspension of contract payments.
Code of Federal Regulations, 2010 CFR
2010-10-01
... damages due the United States under the Contract Work Hours and Safety Standards Act. (See 22.302.) (1) If... the same prime contractor that is subject to either Davis-Bacon Act or Contract Work Hours and Safety... Withholdings Under the Davis-Bacon Act (40 U.S.C. 276(a)) and/or Contract Work Hours and Safety Standards Act...
Setting objectives for managing Key deer
Diefenbach, Duane R.; Wagner, Tyler; Stauffer, Glenn E.
2014-01-01
The U.S. Fish and Wildlife Service (FWS) is responsible for the protection and management of Key deer (Odocoileus virginianus clavium) because the species is listed as Endangered under the Endangered Species Act (ESA). The purpose of the ESA is to protect and recover imperiled species and the ecosystems upon which they depend. There are a host of actions that could possibly be undertaken to recover the Key deer population, but without a clearly defined problem and stated objectives it can be difficult to compare and evaluate alternative actions. In addition, management goals and the acceptability of alternative management actions are inherently linked to stakeholders, who should be engaged throughout the process of developing a decision framework. The purpose of this project was to engage a representative group of stakeholders to develop a problem statement that captured the management problem the FWS must address with Key deer and identify objectives that, if met, would help solve the problem. In addition, the objectives were organized in a hierarchical manner (i.e., an objectives network) to show how they are linked, and measurable attributes were identified for each objective. We organized a group of people who represented stakeholders interested in and potentially affected by the management of Key deer. These stakeholders included individuals who represented local, state, and federal governments, non-governmental organizations, the general public, and local businesses. This stakeholder group met five full days over the course of an eight-week period to identify objectives that would address the following problem:“As recovery and removal from the Endangered Species list is the purpose of the Endangered Species Act, the U.S. Fish and Wildlife Service needs a management approach that will ensure a sustainable, viable, and healthy Key deer population. Urbanization has affected the behavior and population dynamics of the Key deer and the amount and characteristics of available habitat. The identified management approach must balance relevant social and economic concerns, Federal (e.g., Endangered Species Act, Wilderness Act, Refuge Act) and state regulations, and the conservation of biodiversity (e.g., Endangered/Threatened species, native habitat) in the Lower Keys.”The stakeholder group identified four fundamental objectives that are essential to addressing the problem: 1) Maximize a sustainable, viable, and healthy Key deer population, 2) Maximize value of Key deer to the People, 3) Minimize deer-related negative impacts to biodiversity, and 4) Minimize costs. In addition, the group identified 25 additional objectives that, if met, would help meet the fundamental objectives. The objectives network and measurable attributes identified by the stakeholder group can be used in the future to develop and evaluate potential management alternatives.
24 CFR 3282.353 - Submission format.
Code of Federal Regulations, 2013 CFR
2013-04-01
... Submission format. States and private organizations which wish to act as primary inspection agencies shall...) The capacity (DAPIA, IPIA) in which the party wishes to be approved to act; (3) A list of the key...
24 CFR 3282.353 - Submission format.
Code of Federal Regulations, 2012 CFR
2012-04-01
... Submission format. States and private organizations which wish to act as primary inspection agencies shall...) The capacity (DAPIA, IPIA) in which the party wishes to be approved to act; (3) A list of the key...
24 CFR 3282.353 - Submission format.
Code of Federal Regulations, 2011 CFR
2011-04-01
... Submission format. States and private organizations which wish to act as primary inspection agencies shall...) The capacity (DAPIA, IPIA) in which the party wishes to be approved to act; (3) A list of the key...
How Does It Work? Mechanisms of Action in an In-Prison Restorative Justice Program.
Armour, Marilyn; Sliva, Shannon
2018-02-01
Research is limited on mechanisms of action in restorative justice interventions. This multimethods study delineates the change processes underlying a successful in-prison group treatment program by (a) examining shifts in offenders' self-schemas and (b) identifying key program components that influence this movement. Researchers assigned to small groups as "co-facilitators" gathered data using participant observation, semi-structured interviews, and psychological assessments at three time points. Mechanisms of action include group norms and behaviors that contrast with prior experiences and uncover offenders' self-schemas through intrapsychic processes, which prompt them to test and act upon new possible selves through the group process.
The In-Situ Resource Utilization Project Under the New Exploration Enterprise
NASA Technical Reports Server (NTRS)
Larson, William E.; Sanders, Gerald B.
2010-01-01
The In Situ Resource Utilization Project under the Exploration Technology Development Program has been investing in technologies to produce Oxygen from the regolith of the moon for the last few years. Much of this work was demonstrated in a lunar analog field demonstration in February of 2010. This paper will provide an overview of the key technologies demonstrated at the field demonstration will be discussed a long with the changes expected in the ISRU project as a result of the new vision for Space Exploration proposed by the President and enacted by the Congress in the NASA Authorization Act of2010.
Shaping biomedical objects across history and philosophy:a conversation with Hans-Jörg Rheinberger.
García-Sancho, Miguel; González-Silva, Matiana; Jesús Santesmases, María; Rheinberger, Hans-Jörg
2014-01-01
Historical epistemology, according to the historian of science Hans-Jörg Rheinberger, is a space through which "to take experimental laboratory work into the realm of philosophy". This key concept, together with the crucial events and challenges of his career, were discussed in a public conversation which took place on the occasion of Rheinberger's retirement. By making sense of natural phenomena in the laboratory, the act of experimenting shapes the object; it is this shaping which became the core of Rheinberger's own research across biology and philosophy into history. For his intellectual agenda, a history of the life sciences so constructed became "epistemologically demanding".
29 CFR 4.181 - Overtime pay provisions of other Acts.
Code of Federal Regulations, 2010 CFR
2010-07-01
... § 4.180. (b) Contract Work Hours and Safety Standards Act. (1) The Contract Work Hours and Safety... the work performed for the employer is subject to such Act and if, in such workweek, the total hours... not less than 11/2 times their regular rate of pay for all hours worked in excess of the applicable...
29 CFR 1926.11 - Coverage under section 103 of the act distinguished.
Code of Federal Regulations, 2011 CFR
2011-07-01
... of the Contract Work Hours and Safety Standards Act. The application of the overtime requirements is... Contract Work Hours and Safety Standards Act, a contract must be one which (1) is entered into under a... statute “providing wage standards for such work.” The statutes “providing wage standards for such work...
48 CFR 22.403-3 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contract Work Hours and... Standards for Contracts Involving Construction 22.403-3 Contract Work Hours and Safety Standards Act. The Contract Work Hours and Safety Standards Act (40 U.S.C. 3701 et seq.) requires that certain contracts (see...
29 CFR 5.8 - Liquidated damages under the Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 1 2011-07-01 2011-07-01 false Liquidated damages under the Contract Work Hours and Safety... APPLICABLE TO NONCONSTRUCTION CONTRACTS SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and Procedures § 5.8 Liquidated damages under the Contract Work Hours...
29 CFR 1926.11 - Coverage under section 103 of the act distinguished.
Code of Federal Regulations, 2010 CFR
2010-07-01
... of the Contract Work Hours and Safety Standards Act. The application of the overtime requirements is... Contract Work Hours and Safety Standards Act, a contract must be one which (1) is entered into under a... statute “providing wage standards for such work.” The statutes “providing wage standards for such work...
29 CFR 5.8 - Liquidated damages under the Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 1 2010-07-01 2010-07-01 true Liquidated damages under the Contract Work Hours and Safety... APPLICABLE TO NONCONSTRUCTION CONTRACTS SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and Procedures § 5.8 Liquidated damages under the Contract Work Hours...
KEY COMPARISON: Final report of the CCQM-K56: Ca, Fe, Zn and Cu in whole fat soybean powder
NASA Astrophysics Data System (ADS)
Liandi, Ma; Qian, Wang
2010-01-01
The CCQM-K56 key comparison was organized by the Inorganic Analysis Working Group (IAWG) of CCQM as a follow-up to completed pilot study CCQM-P64 to test the abilities of national metrology institutes to measure the amount content of nutritious elements in whole fat soybean powder. A pilot study CCQM-P64.1 was conducted in parallel with this key comparison. The National Institute of Metrology (NIM), P. R. China, acted as the coordinating laboratory. Eleven NIMs participated in CCQM-K56. Four elements - Ca, Fe, Zn and Cu - in different concentration levels have been studied. Different measurement methods (IDMS, ICP-MS, ICP-OES, AAS and INAA) and the microwave digestion method were used. The agreement of the results of CCQM-K56 is very good, and obviously better than that of the original P64. It shows that the capability of all of the participants had been promoted from the original pilot study to this key comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Learning Curve: Charting Progress on Pesticide Use and the Healthy Schools Act.
ERIC Educational Resources Information Center
McKendry, Corina
This progress report investigated two key questions regarding the Healthy Schools Act and pesticide use in California's schools. First, has the act reduced overall pesticide use in California's largest school districts? Second, having had a year to come into compliance, are surveyed districts meeting their responsibilities? Based on a survey of…
Students with Disabilities at Degree-Granting Postsecondary Institutions. First Look. NCES 2011-018
ERIC Educational Resources Information Center
Raue, Kimberley; Lewis, Laurie
2011-01-01
Growing enrollments of students with disabilities in postsecondary education along with recent key legislation such as the Americans with Disabilities Act Amendments Act of 2008 and the 2008 Higher Education Opportunity Act, have generated considerable interest in research on accessibility of higher education for students with disabilities. This…
The endangered species act: science, policy, and politics.
Bean, Michael J
2009-04-01
The Endangered Species Act of 1973 is one of the nation's most significant and most controversial environmental laws. Over three-and-a-half decades, it has profoundly influenced both private and federal agency behavior. As the scope of that influence has come to be recognized, a law that is ostensibly to be guided by science has inevitably become entangled in politics. The generality of many of the law's key provisions has produced continuing uncertainty and conflict over some basic issues. Among these are what species or other taxa are potentially subject to the Act's protections, what the extent of those protections is, and whether the Act's ultimate goal of recovery is one that is being effectively achieved. New challenges face the administrators of this law, including that of incorporating climate change considerations into the decisions made under the Act, and responding to the information made available by recent advances in genetics. This paper provides a brief overview of the Endangered Species Act's history and its key provisions, and a more in-depth look at some of the current and recurrent controversies that have attended its implementation.
Artiles, Karen; Anastasia, Stephanie; McCusker, Derek; Kellogg, Douglas R.
2009-01-01
The key molecular event that marks entry into the cell cycle is transcription of G1 cyclins, which bind and activate cyclin-dependent kinases. In yeast cells, initiation of G1 cyclin transcription is linked to achievement of a critical cell size, which contributes to cell-size homeostasis. The critical cell size is modulated by nutrients, such that cells growing in poor nutrients are smaller than cells growing in rich nutrients. Nutrient modulation of cell size does not work through known critical regulators of G1 cyclin transcription and is therefore thought to work through a distinct pathway. Here, we report that Rts1, a highly conserved regulatory subunit of protein phosphatase 2A (PP2A), is required for normal control of G1 cyclin transcription. Loss of Rts1 caused delayed initiation of bud growth and delayed and reduced accumulation of G1 cyclins. Expression of the G1 cyclin CLN2 from an inducible promoter rescued the delayed bud growth in rts1Δ cells, indicating that Rts1 acts at the level of transcription. Moreover, loss of Rts1 caused altered regulation of Swi6, a key component of the SBF transcription factor that controls G1 cyclin transcription. Epistasis analysis revealed that Rts1 does not work solely through several known critical upstream regulators of G1 cyclin transcription. Cells lacking Rts1 failed to undergo nutrient modulation of cell size. Together, these observations demonstrate that Rts1 is a key player in pathways that link nutrient availability, cell size, and G1 cyclin transcription. Since Rts1 is highly conserved, it may function in similar pathways in vertebrates. PMID:19911052
National Environmental Change Information System Case Study
NASA Technical Reports Server (NTRS)
Goodman, S. J.; Ritschard, R.; Estes, M. G., Jr.; Hatch, U.
2001-01-01
The Global Hydrology and Climate Center and NASA's Marshall Space Flight Center conducted a fact-finding case study for the Data Management Working Group (DMWG), now referred to as the Data and Information Working Group (DIWG), of the U.S. Global Change Research Program (USGCRP) to determine the feasibility of an interagency National Environmental Change Information System (NECIS). In order to better understand the data and information needs of policy and decision makers at the national, state, and local level, the DIWG asked the case study team to choose a regional water resources issue in the southeastern United States that had an impact on a diverse group of stakeholders. The southeastern United States was also of interest because the region experiences interannual climatic variations and impacts due to El Nino and La Nina. Jointly, with input from the DIWG, a focus on future water resources planning in the Apalachicola-Chattahoochee-Flint (ACF) River basins of Alabama, Georgia, and Florida was selected. A tristate compact and water allocation formula is currently being negotiated between the states and U.S. Army Corps of Engineers (COE) that will affect the availability of water among competing uses within the ACF River basin. All major reservoirs on the ACF are federally owned and operated by the U.S. Army COE. A similar two-state negotiation is ongoing that addresses the water allocations in the adjacent Alabama-Coosa-Tallapoosa (ACT) River basin, which extends from northwest Georgia to Mobile Bay. The ACF and ACT basins are the subject of a comprehensive river basin study involving many stakeholders. The key objectives of this case study were to identify specific data and information needs of key stakeholders in the ACF region, determine what capabilities are needed to provide the most practical response to these user requests, and to identify any limitations in the use of federal data and information. The NECIS case study followed the terms of reference developed by the interagency DIWG. The case study "lessons learned" and "key findings" offer guidelines and considerations to the DMWG for the development and implementation of a NECIS that would support the data and information needs of policy and decision makers at the national, state, and local level.
Rodríguez Jareño, Mari Cruz; De Montserrat I Nonó, Jaume
In Spain, the limited preventive usefulness of health surveillance is determined by the indiscriminate use of nonspecific "generic" health examinations aimed at producing a "fitness for work list", presumably allowing companies to comply with health and safety regulations. This study aimed to produce a technical interpretation of the Spanish Prevention of Risks at Work Act and propose a new conceptual framework to favour greater preventive usefulness of health surveillance within the current regulatory framework. Using qualitative techniques of content analysis, the text of the Law was studied, the key concepts that impeded the fulfilment of the preventive objectives of health surveillance were identified, and a technical interpretation adjusted to regulations was made in order to propose a new conceptual framework RESULTS: This conceptual framework would include: clearly differentiating health surveillance from health examinations (one of its instruments) and from fitness for work evaluations (an independent concept in itself); restricting mandatory health surveillance to situations in which it is "imperative" to carry it out because of the existence of a substantial risk to workers or third parties, including potentially vulnerable workers; and communicating the results of health surveillance through preventive recommendations to the company, reserving fitness for duty certificates -always based on clear, pre-established and justified criteria in relation to risk- for mandatory surveillance. The proposed new conceptual framework falls within the scope of the Spanish Prevention of Risks at Work Act, and its implementation could contribute to improving the preventive usefulness of health surveillance without the need to reform the legislation. Copyright belongs to the Societat Catalana de Salut Laboral.
Leading multi-professional teams in the children's workforce: an action research project.
Stuart, Kaz
2012-01-01
The 2004 Children Act in the UK saw the introduction of integrated working in children's services. A raft of change followed with processes designed to make joint working easier, and models and theories to support the development of integrated work. This paper explores the links between key concepts and practice. A practitioner action research approach is taken using an autoethnographic account kept over six months. The research question was, to what extent is this group collaborating? When the architecture of practice was revealed, differences between espoused and real practice could be seen. Whilst understanding and displaying the outward signs of an effective multi professional group, the individuals did not trust one another. This was exhibited by covert interprofessional issues. As a result, collaborative inertia was achieved. This realisation prompted them to participate in further developmental and participative action research. The paper concludes that trust and relational agency are central to effective leadership of multi professional teams.
Leading multi-professional teams in the children’s workforce: an action research project
Stuart, Kaz
2012-01-01
Introduction The 2004 Children Act in the UK saw the introduction of integrated working in children’s services. A raft of change followed with processes designed to make joint working easier, and models and theories to support the development of integrated work. This paper explores the links between key concepts and practice. Methods A practitioner action research approach is taken using an autoethnographic account kept over six months. The research question was, to what extent is this group collaborating? Results When the architecture of practice was revealed, differences between espoused and real practice could be seen. Whilst understanding and displaying the outward signs of an effective multi professional group, the individuals did not trust one another. This was exhibited by covert interprofessional issues. As a result, collaborative inertia was achieved. This realisation prompted them to participate in further developmental and participative action research. Conclusion The paper concludes that trust and relational agency are central to effective leadership of multi professional teams. PMID:22371690
ERIC Educational Resources Information Center
Work Keys USA, 1998
1998-01-01
"Work Keys" is a comprehensive program for assessing and teaching workplace skills. This serial "special issue" features 18 first-hand reports on Work Keys projects in action in states across North America. They show how the Work Keys is helping businesses and educators solve the challenge of building a world-class work force.…
Key observations from the NHLBI Asthma Clinical Research Network.
Szefler, Stanley J; Chinchilli, Vernon M; Israel, Elliot; Denlinger, Loren Clark; Lemanske, Robert F; Calhoun, William; Peters, Stephen P
2012-05-01
The National Heart, Lung and Blood Institute (NHLBI) Asthma Clinical Research Network (ACRN) recently completed its work after 20 years of collaboration as a multicentre clinical trial network. When formed, its stated mission was to perform multiple controlled clinical trials for treating patients with asthma by dispassionately examining new and existing therapies, and to rapidly communicate its findings to the medical community. The ACRN conducted 15 major clinical trials. In addition, clinical data, manual of operations, protocols and template informed consents from all ACRN trials are available via NHLBI BioLINCC (https://biolincc.nhlbi.nih.gov/studies/). This network contributed major insights into the use of inhaled corticosteroids, short-acting and long-acting ß-adrenergic agonists, leukotriene receptor antagonists, and novel agents (tiotropium, colchicine and macrolide antibiotics). They also pioneered studies of the variability in drug response, predictors of treatment response and pharmacogenetics. This review highlights the major research observations from the ACRN that have impacted the current management of asthma.
29 CFR 5.7 - Reports to the Secretary of Labor.
Code of Federal Regulations, 2011 CFR
2011-07-01
... SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and..., liquidated damages assessed under the Contract Work Hours and Safety Standards Act, corrective measures taken... respect to contractors and subcontractors, their contracts, and the nature of the contract work as the...
29 CFR 5.7 - Reports to the Secretary of Labor.
Code of Federal Regulations, 2010 CFR
2010-07-01
... SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and..., liquidated damages assessed under the Contract Work Hours and Safety Standards Act, corrective measures taken... respect to contractors and subcontractors, their contracts, and the nature of the contract work as the...
29 CFR 6.19 - Decision of the Administrative Law Judge.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Proceedings Under the Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for... have violated the provisions of the Contract Work Hours and Safety Standards Act, the Administrative... Administrative Law Judge shall make no findings regarding liquidated damages under the Contract Work Hours and...
29 CFR 6.19 - Decision of the Administrative Law Judge.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Proceedings Under the Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for... have violated the provisions of the Contract Work Hours and Safety Standards Act, the Administrative... Administrative Law Judge shall make no findings regarding liquidated damages under the Contract Work Hours and...
Heuer, G
2001-10-01
This paper is a preliminary communication of several years of research into the life and work of the Austrian psychoanalyst and anarchist Otto Gross (1877-1920). Although he played a pivotal role in the birth of modernity, acting as a significant influence upon psychiatry, psychoanalysis, ethics, sociology and literature, he has remained virtually unknown to this day. Following a biographical sketch and an overview of his main theoretical contributions, the impact of Gross' life and work on the development of analytical theory and practice is described. His relationship with some of the key figures in psychoanalysis is presented, with particular emphasis on his connections to Jung. The paper concludes with an account of relevant contemporary interest in his work: the founding of the International Otto Gross Society, the first edition of The Collected Works of Otto Gross on the Internet, and the 1st and 2nd International Otto Gross Congresses which took place in Berlin in 1999 and at the Burghölzli Clinic, Zürich, in October 2000.
The EEOC's New Equal Pay Act Guidelines.
ERIC Educational Resources Information Center
Greenlaw, Paul S.; Kohl, John P.
1982-01-01
Analyzes the new guidelines for enforcement of the Equal Pay Act and their implications for personnel management. Argues that there are key problem areas in the new regulations arising from considerable ambiguity and uncertainty about their interpretation. (SK)
Implementing Immediate Postpartum Long-Acting Reversible Contraception Programs.
Hofler, Lisa G; Cordes, Sarah; Cwiak, Carrie A; Goedken, Peggy; Jamieson, Denise J; Kottke, Melissa
2017-01-01
To understand the most important steps required to implement immediate postpartum long-acting reversible contraception (LARC) programs in different Georgia hospitals and the barriers to implementing such a program. This was a qualitative study. We interviewed 32 key personnel from 10 Georgia hospitals working to establish immediate postpartum LARC programs. Data were analyzed using directed qualitative content analysis principles. We used the Stages of Implementation to organize participant-identified key steps for immediate postpartum LARC into an implementation guide. We compared this guide to hospitals' implementation experiences. At the completion of the study, LARC was available for immediate postpartum placement at 7 of 10 study hospitals. Participants identified common themes for the implementation experience: team member identification and ongoing communication, payer preparedness challenges, interdependent department-specific tasks, and piloting with continuing improvements. Participants expressed a need for anticipatory guidance throughout the process. Key first steps to immediate postpartum LARC program implementation were identifying project champions, creating an implementation team that included all relevant departments, obtaining financial reassurance, and ensuring hospital administration awareness of the project. Potential barriers included lack of knowledge about immediate postpartum LARC, financial concerns, and competing clinical and administrative priorities. Hospitals that were successful at implementing immediate postpartum LARC programs did so by prioritizing clear communication and multidisciplinary teamwork. Although the implementation guide reflects a comprehensive assessment of the steps to implementing immediate postpartum LARC programs, not all hospitals required every step to succeed. Hospital teams report that implementing immediate postpartum LARC programs involves multiple departments and a number of important steps to consider. A stage-based approach to implementation, and a standardized guide detailing these steps, may provide the necessary structure for the complex process of implementing immediate postpartum LARC programs in the hospital setting.
Local Homeless Education Liaisons. McKinney-Vento Law into Practice Brief Series
ERIC Educational Resources Information Center
National Center for Homeless Education at SERVE, 2008
2008-01-01
Subtitle VII-B of the McKinney-Vento Homeless Assistance Act, reauthorized by Title X, Part C, of the No Child Left Behind Act, ensures educational rights and protections for children and youth experiencing homelessness. This brief explains the key provisions in the Act concerning the roles and responsibilities of the local homeless education…
ERIC Educational Resources Information Center
Nursall, John G.
1989-01-01
Outlined are key provisions, relevant to education, of Title VII of the Civil Rights Act of 1964 and the Equal Pay Act of 1963. Administrative guidelines to insure compliance are presented, as well as preventive measures that reduce vulnerability to charges of discrimination in hiring, promotion, and compensation. (IAH)
Defense.gov Special Report: Travels With Lynn - April 2011
Department of Defense Submit Search April 2011 News Photos Top Stories Lynn Opens New High-tech Countertrafficking Center NAVAL AIR STATION KEY WEST, Fla., April 19, 2011 - A new, high-tech command center at Naval & Security Link Disclaimer Recovery Act FOIA USA.gov No FEAR Act Plain Writing Act of 2010
Education for Liberal Democracy: Fred Clarke and the 1944 Education Act
ERIC Educational Resources Information Center
Ku, Hsiao-Yuh
2013-01-01
Fred Clarke (1880-1952), an English educationist, emerged as a leading figure with his liberal approach alongside such key figures as R. H. Tawney and Cyril Norwood in the reform leading to the 1944 Education Act. Many of his reform proposals, which were provided by the new Act, reflected his ideals of liberal democracy. Nevertheless, his…
Speech-Act Theory as a New Way of Conceptualizing the "Student Experience"
ERIC Educational Resources Information Center
Fisher, Andrew
2010-01-01
This article has four aims. The first is to characterize the key features of speech-act theory, and, in particular, to show that there is a genuine distinction between the sound uttered when someone is speaking (locution), the effect the speech has (perlocution) and the very "act" of speaking (the illocution). Secondly, it aims to…
Code of Federal Regulations, 2010 CFR
2010-07-01
... WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and Procedures § 5.6... where liquidated damages may be assessed under the Contract Work Hours and Safety Standards Act, the...
Code of Federal Regulations, 2011 CFR
2011-07-01
... WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and Procedures § 5.6... where liquidated damages may be assessed under the Contract Work Hours and Safety Standards Act, the...
29 CFR 6.20 - Petition for review.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... under the Service Contract Act, and/or the aggravated or willful violations of the Contract Work Hours...
29 CFR 6.20 - Petition for review.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... under the Service Contract Act, and/or the aggravated or willful violations of the Contract Work Hours...
12 CFR 7.5005 - National bank acting as digital certification authority.
Code of Federal Regulations, 2012 CFR
2012-01-01
... persons associated with a particular public/private key pair. As part of this service, the bank may also maintain a listing or repository of public keys. (b) A national bank may issue digital certificates verifying attributes in addition to identity of persons associated with a particular public/private key pair...
12 CFR 7.5005 - National bank acting as digital certification authority.
Code of Federal Regulations, 2014 CFR
2014-01-01
... persons associated with a particular public/private key pair. As part of this service, the bank may also maintain a listing or repository of public keys. (b) A national bank may issue digital certificates verifying attributes in addition to identity of persons associated with a particular public/private key pair...
12 CFR 7.5005 - National bank acting as digital certification authority.
Code of Federal Regulations, 2013 CFR
2013-01-01
... persons associated with a particular public/private key pair. As part of this service, the bank may also maintain a listing or repository of public keys. (b) A national bank may issue digital certificates verifying attributes in addition to identity of persons associated with a particular public/private key pair...
12 CFR 7.5005 - National bank acting as digital certification authority.
Code of Federal Regulations, 2011 CFR
2011-01-01
... persons associated with a particular public/private key pair. As part of this service, the bank may also maintain a listing or repository of public keys. (b) A national bank may issue digital certificates verifying attributes in addition to identity of persons associated with a particular public/private key pair...
Lynch, John
2004-01-01
This paper seeks to gain an insight into the behavior of a large NHS trust, in its attempt to meet a 90 percent patient access target, in a week long national audit in March 2003. Why did individuals act in dramatically different ways to their norm over this period. The work of Michel Foucault is used to explore these issues. The discourses of power, knowledge, discipline and governmentality are identified as key foucaudian themes that offer an alternative interpretation of how individuals behave in their place of work. The importance of the historical context of discourse within the NHS cannot be underestimated in shaping the behavior of individuals and groups today. Power and knowledge permeate NHS organizations through disciplinary practices and dressage. Governmentality seeks to maintain the status quo through disciplinary processes such as national healthcare targets. The natural response of NHS organizations is therefore, to seek order and conformity rather than disorder and conflict.
Federal Workplace Laws: Are Business Work Experience Programs in Compliance?
ERIC Educational Resources Information Center
Rader, Martha H.; Kurth, Linda A.
1999-01-01
Reviews federal laws (Fair Labor Standard Act's child labor regulations, Occupational Safety and Health Act, Immigration Reform and Control Act) for their implications for cooperative education and school-to-work programs. (SK)
Chen, Walter; Shiao, Wen-Been; Lin, Blossom Yen-Ju; Lin, Cheng-Chieh
2013-12-01
Different geographical areas with unique social cultures or societies might influence immigrant health. This study examines whether health inequities and different social factors exist regarding the health of rural and urban married Asian immigrants. A survey was conducted on 419 rural and 582 urban married Asian immigrants in Taiwan in 2009. Whereas the descriptive results indicate a worse mental health status between rural and urban married Asian immigrants, rural married immigrants were as mentally healthy as urban ones when considering different social variables. An analysis of regional stratification found different social-determinant patterns on rural and urban married immigrants. Whereas social support is key for rural immigrant physical and mental health, acculturation (i.e., language proficiency), socioeconomics (i.e., working status), and family structure (the number of family members and children living in the family) are key to the mental health of urban married immigrants in addition to social support. This study verifies the key roles of social determinants on the subjective health of married Asian immigrants. Area-differential patterns on immigrant health might act as a reference for national authorities to (re)focus their attention toward more area-specific approaches for married Asian immigrants.
78 FR 4307 - Current Good Manufacturing Practice Requirements for Combination Products
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-22
.... Rationale for the Rulemaking B. The Proposed Rule C. The Final Rule II. Comments on the Proposed Rule A. General B. What is the scope of this subpart? (Sec. 4.1) C. How does FDA define key terms and phrases in... Act (the PHS Act) (42 U.S.C. 262). All biological products regulated under the PHS Act meet the...
The personal health record: consumers banking on their health.
Ball, Marion J; Costin, Melinda Y; Lehmann, Christoph
2008-01-01
With personal health records (PHRs) acting much like ATM cards, increasingly wired consumers can "bank on health", accessing their own personal health information and a wide array of services. Consumer-owned, the PHR is dependent upon the existence of the legal electronic medical record (EMR) and interoperability. Working PHRs are in place in Veterans Health Administration, private health care institutions, and in the commercial sector. By allowing consumers to become involved in their own care, the PHR creates new roles and relationships. New tools change the clinician's workflow and thought flow, and pose new challenges for consumers. Key components of the PHR include the EMR and regional health information organizations (RHIOs); key strategies focus on human factors in successful project management. Online resources provided by the National Library of Medicine and Health On the Net help address consumer needs for information that is reliable and understandable. The growth of self-management tools adds to the challenge and the promise of PHRs for clinicians and consumers alike.
29 CFR 1975.1 - Purpose and scope.
Code of Federal Regulations, 2010 CFR
2010-07-01
... either as a matter of interpretation of the intent and terms of the Act or as a matter of policy... determined. Section 4(b)(1) of the Act provides that the statute shall be inapplicable to working conditions... considered an employer covered by the Act, and yet standards issued under the Act respecting certain working...
18 CFR 367.1070 - Account 107, Construction work in progress.
Code of Federal Regulations, 2011 CFR
2011-04-01
... ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE... NATURAL GAS ACT Balance Sheet Chart of Accounts § 367.1070 Account 107, Construction work in progress. (a... research, development, and demonstration projects for construction of facilities are to be included in a...
Module 4: Work-Family Policy in the United States. Work-Family Curriculum Guide
ERIC Educational Resources Information Center
Kossek, Ellen Ernst; Leana, Carrie; MacDermid, Shelley; Pitt-Catsouphes, Marcie; Raskin, Patricia; Secret, Mary; Shulkin, Sandee; Sweet, Stephen
2006-01-01
Public policy affects the experiences of workers and their families, both directly and indirectly. For example, employment-focused statutes such as the Fair Labor Standards Act (FLSA), the Employment Retirement and Income Security Act, the Occupational Health and Safety Act, and the Age Discrimination in Employment Act establish frameworks for…
29 CFR 4.117 - Work subject to requirements of Walsh-Healey Act.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Application of the McNamara-O'Hara Service Contract Act Specific Exclusions § 4.117 Work subject to... work required to be done in accordance with the provision of the Walsh-Healey Public Contracts Act” (49...., specifications or requirements, rather than for “contracts” subject to the Walsh-Healey Act. The purpose of the...
75 FR 28649 - State of Arizona Resource Advisory Council Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-21
... Policy and Management Act of 1976 and the Federal Advisory Committee Act of 1972, the U.S. Department of... Managers' Reports; and reports by RAC working groups. A public comment period will be provided at 11:30 a.m... brief review of the Recreation Enhancement Act (REA) Working Group Report, REA Working Group meeting...
Krannitz, Morgan A; Grandey, Alicia A; Liu, Songqi; Almeida, David A
2015-07-01
Surface acting (i.e., faking and suppressing emotions at work) is repeatedly linked to employee negative moods and emotional exhaustion, but the consequences may also go beyond work boundaries. We provide a unique theoretical integration of these 2 emotional labor consequences with 2 work-to-family conflict mechanisms, mood spillover and resource drain, to explain why surface acting is likely to create marital partner discontent (i.e., partner's perceived work-to-family conflict and desire for the employee to quit). A survey of 197 hotel managers and their marital partners supported that managers' surface acting was directly related to their partner wanting them to quit, and indirectly to partner's perception of work-to-family conflict via exhaustion consistent with the resource drain mechanism. Anxiety from surface acting had an indirect mediating effect on marital partner discontent through exhaustion. Importantly, controlling for dispositional negativity and job demands did not weaken these effects. Implications for theory and future research integrating work-family and emotional labor are discussed. (c) 2015 APA, all rights reserved).
Workplace Surface Acting and Marital Partner Discontent: Anxiety and Exhaustion Spillover Mechanisms
Krannitz, Morgan A.; Grandey, Alicia A.; Liu, Songqi; Almeida, David A.
2015-01-01
Surface acting (i.e., faking and suppressing emotions at work) is repeatedly linked to employee negative moods and emotional exhaustion, but the consequences may also go beyond work boundaries. We provide a unique theoretical integration of these two emotional labor consequences with two work-to-family conflict mechanisms, mood spillover and resource drain, in order to explain why surface acting is likely to create marital partner discontent (i.e., partner’s perceived work-to-family conflict and desire for the employee to quit). A survey of 197 hotel managers and their marital partners supported that managers’ surface acting was directly related to their partner wanting them to quit, and indirectly to partner’s perception of work-to-family conflict via exhaustion consistent with the resource drain mechanism. Anxiety from surface acting had an indirect mediating effect on marital partner discontent through exhaustion. Importantly, controlling for dispositional negativity and job demands did not weaken these effects. Implications for theory and future research integrating work-family and emotional labor are discussed. PMID:25705910
Detection of saliva-range glucose concentrations using organic thin-film transistors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Elkington, D.; Belcher, W. J.; Dastoor, P. C.
We describe the development of a glucose sensor through direct incorporation of an enzyme (glucose oxidase) into the gate of an organic thin film transistor (OTFT). We show that glucose diffusion is the key determinant of the device response time and present a mechanism of glucose sensing in these devices that involves protonic doping of the transistor channel via enzymatic oxidation of glucose. The integrated OTFT sensor is sensitive across 4 decades of glucose concentration; a range that encompasses both the blood and salivary glucose concentration levels. As such, this work acts as a proof-of-concept for low-cost printed biosensors formore » salivary glucose.« less
42 CFR 447.51 - Requirements and options.
Code of Federal Regulations, 2011 CFR
2011-10-01
... the Act: (i) A pregnant woman or an infant under one year of age described in subparagraph (A) or (B...)(XVI) of the Act and the Ticket to Work and Work Incentives Improvement Act of 1999 (TWWIIA); and (iv...
Final report on RMO Vickers key comparison COOMET M.H-K1
NASA Astrophysics Data System (ADS)
Aslanyan, E.; Menelao, F.; Herrmann, K.; Aslanyan, A.; Pivovarov, V.; Galat, E.; Dovzhenko, Y.; Zhamanbalin, M.
2013-01-01
This report describes a COOMET key comparison on Vickers hardness scales involving five National Metrology Institutes: PTB (Germany), BelGIM (Belarus), NSC IM (Ukraine), KazInMetr (Kazakhstan) and VNIIFTRI (Russia). The pilot laboratory was VNIIFTRI, and PTB acted as the linking institute to key comparisons CCM.H-K1.b and CCM.H-K1.c conducted for the Vickers hardness scales HV1 and HV30, respectively. The comparison was also conducted for the HV5 Vickers hardness scale, since this scale is most frequently used in practice in Russia and CIS countries that work according to GOST standards. In the key comparison, two sets of hardness reference blocks for the Vickers hardness scales HV1, HV5 and HV30 consisting each of three hardness reference blocks with hardness levels of 450 HV and 750 HV were used. The measurement results and uncertainty assessments for HV1 and HV30 hardness scales, as announced by BelGIM, NSC IM, KazInMetr and VNIIFTRI, are in good agreement with the key comparison reference values of CCM.H-K1.b and CCM.H-K1.c. The comparison results for the HV5 hardness scale are viewed as additional information, since up to today no CCM key comparisons on this scale have yet been carried out. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
ERIC Educational Resources Information Center
Marion, Scott
2016-01-01
The Elementary and Secondary Schools Education Act (ESEA) was finally reauthorized as the Every Student Succeeds Act (ESSA). The reauthorization was long overdue and with its passage comes much hype and some misinformation about what the law permits and does not permit. The purpose of this brief is to outline some of the key accountability…
ERIC Educational Resources Information Center
Riley, William T.; Blizinsky, Katherine D.
2017-01-01
The 21st Century Cures Act provides funding for key initiatives relevant to the behavioral and social sciences and includes administrative provisions that facilitate health research and increase the privacy protections of research participants. At about the same time as the passage of the Act, the National Institutes of Health Office of Behavioral…
The Role of OSHA in Safety and Health. Module SH-02. Safety and Health.
ERIC Educational Resources Information Center
Center for Occupational Research and Development, Inc., Waco, TX.
This student module on the role of OSHA (Occupational Safety and Health Act) in Safety and Health is one of 50 modules concerned with job safety and health. This module looks at the OSHA Act, its aims, and the rights and responsibilities of employers and workers under the Act. Following the introduction, 16 objectives (each keyed to a page in the…
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. House Committee on Education and the Workforce.
This hearing on the Juvenile Crime Control and Delinquency Prevention Act (H.R. 1150) presents testimonies from individuals who administer the key federal programs that address problems of juvenile delinquency and runaway and homeless youth. As the committee looks toward reauthorizing the Juvenile Justice Act, it is suggested that the act needs a…
Montes, J Henry; Webb, Susan C
2015-01-01
The Affordable Care Act brings a renewed emphasis on the importance of public health services and those whose occupations are defined by performing the essential public health functions. The Affordable Care Act Prevention and Public Health Fund is a signal to the field that its work is important and critical to the health of the nation. Recent reports by the Institute of Medicine describe the changing dimensions of public health work in primary care integration and the need for enhanced financing of public health as investment. Gaining knowledge about the public health workforce, that is, how many workers there are and what they are doing, is of growing interest and concern for the field. Although enumeration of the public health workforce has been attempted several times by the federal government beginning as early as 1982, it was not until the year 2000 that a major effort was undertaken to obtain more complete information. Limitations that hampered Enumeration 2000 have persisted however. With implementation of the Affordable Care Act and other new ventures, key federal agencies are developing strategies to pursue a systemic and systematic enumeration and consistent taxonomy process. Included in these efforts is use of the Bureau of Labor Statistics, Standard Occupational Classification system. A clear and accurate understanding of the public health workforce and its characteristics is a major challenge. A well-constructed, systematic enumeration process can add to our understanding of the nature and functions of that workforce. In addition, discussion of enumeration must include the need for a consensus within the field that leads to a consistent taxonomy for the public health occupations. This article will provide a stage-setting brief of historical actions regarding enumeration, and it will examine selected enumeration activities taking place currently. It will discuss positive and negative implications facing public health and the potential for enhancing the existing Standard Occupational Classification system to aid enumeration studies.
A phosphoinositide-binding cluster in cavin1 acts as a molecular sensor for cavin1 degradation
Tillu, Vikas A.; Kovtun, Oleksiy; McMahon, Kerrie-Ann; Collins, Brett M.; Parton, Robert G.
2015-01-01
Caveolae are abundant surface organelles implicated in a range of cellular processes. Two classes of proteins work together to generate caveolae: integral membrane proteins termed caveolins and cytoplasmic coat proteins called cavins. Caveolae respond to membrane stress by releasing cavins into the cytosol. A crucial aspect of this model is tight regulation of cytosolic pools of cavin under resting conditions. We now show that a recently identified region of cavin1 that can bind phosphoinositide (PI) lipids is also a major site of ubiquitylation. Ubiquitylation of lysines within this site leads to rapid proteasomal degradation. In cells that lack caveolins and caveolae, cavin1 is cytosolic and rapidly degraded as compared with cells in which cavin1 is associated with caveolae. Membrane stretching causes caveolar disassembly, release of cavin complexes into the cytosol, and increased proteasomal degradation of wild-type cavin1 but not mutant cavin1 lacking the major ubiquitylation site. Release of cavin1 from caveolae thus leads to exposure of key lysine residues in the PI-binding region, acting as a trigger for cavin1 ubiquitylation and down-regulation. This mutually exclusive PI-binding/ubiquitylation mechanism may help maintain low levels of cytosolic cavin1 in resting cells, a prerequisite for cavins acting as signaling modules following release from caveolae. PMID:26269585
20 CFR 220.29 - Work that is considered substantial gainful activity.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RAILROAD RETIREMENT ACT DETERMINING DISABILITY Disability Under the Railroad Retirement Act for Any Regular Employment § 220.29 Work that is considered substantial gainful activity. Work is considered to be...
28 CFR Appendix A to Part 70 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-07-01
... Department. 4. Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where applicable, all... standard work week of forty hours. Work in excess of the standard work week is permissible provided that... all hours worked in excess of forty hours in the work week. Section 107 of the Act is applicable to...
38 CFR Appendix A to Part 49 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-07-01
... Federal awarding agency. 4. Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where... the basis of a standard work week of 40 hours. Work in excess of the standard work week is permissible... hours worked in excess of 40 hours in the work week. Section 107 of the Act is applicable to...
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Committee on Indian Affairs.
A Senate committee hearing received testimony on the implementation of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 in American Indian and Alaska Native tribal communities. The act provided authority for tribal governments to administer welfare programs formerly administered by the states but did not provide funds to…
Unravelling the reaction mechanism of matrix metalloproteinase 3 using QM/MM calculations
NASA Astrophysics Data System (ADS)
Feliciano, Gustavo Troiano; da Silva, Antônio José Roque
2015-07-01
The matrix metalloproteinase family (MMP) constitutes a family of zinc (Zn) proteases that catalyze the breaking of peptide bonds in proteins. These enzymes are very promising drug targets, since they are involved in remodeling and degradation of the extracellular matrix, which is a key process required for cancer metastasis, and thus, their reaction mechanism has been an area of intensive research. Early proposal based on acid base catalyzed hydrolysis, suggested that a conserved zinc bound water molecule acted as the nucleophile attacking the peptide bond carbon, after being activated by essential glutamate. The possibility of a direct nucleophilic attack by the enzyme, performed by the glutamate was also suggested. These are the key yet unsolved issues about MMP reaction mechanism. In the present work, we used hybrid quantum/classical calculations to analyze the structure and energetics of different possible hydrolysis reaction paths. The results support a water mediated mechanism, where both the nucleophile water molecule and the carbonyl oxygen of the scissile peptide bond are coordinated to zinc in the reactive configuration, while the essential glutamate acts as the base accepting the proton from the nucleophilic water. Formation of the carbon-oxygen bond and breaking of carbon-nitrogen bond were found to be concerted events, with a computed barrier of 14.8 kcal/mol. Substrate polarization was found to be important for the observed reaction mechanism, and a substantial change in the metal coordination environment was observed, particularly, regarding the zinc-histidine coordination.
Sommanustweechai, Angkana; Chanvatik, Sunicha; Sermsinsiri, Varavoot; Sivilaikul, Somsajee; Patcharanarumol, Walaiporn; Yeung, Shunmay; Tangcharoensathien, Viroj
2018-02-01
To analyse how antibiotics are imported, manufactured, distributed and regulated in Thailand. We gathered information, on antibiotic distribution in Thailand, in in-depth interviews - with 43 key informants from farms, health facilities, pharmaceutical and animal feed industries, private pharmacies and regulators- and in database and literature searches. In 2016-2017, licensed antibiotic distribution in Thailand involves over 700 importers and about 24 000 distributors - e.g. retail pharmacies and wholesalers. Thailand imports antibiotics and active pharmaceutical ingredients. There is no system for monitoring the distribution of active ingredients, some of which are used directly on farms, without being processed. Most antibiotics can be bought from pharmacies, for home or farm use, without a prescription. Although the 1987 Drug Act classified most antibiotics as "dangerous drugs", it only classified a few of them as prescription-only medicines and placed no restrictions on the quantities of antibiotics that could be sold to any individual. Pharmacists working in pharmacies are covered by some of the Act's regulations, but the quality of their dispensing and prescribing appears to be largely reliant on their competences. In Thailand, most antibiotics are easily and widely available from retail pharmacies, without a prescription. If the inappropriate use of active pharmaceutical ingredients and antibiotics is to be reduced, we need to reclassify and restrict access to certain antibiotics and to develop systems to audit the dispensing of antibiotics in the retail sector and track the movements of active ingredients.
Purchasing health care in China: experiences, opportunities and challenges.
Yip, Winnie; Hanson, Kara
2009-01-01
Purchasing has been promoted as a key policy instrument to improve health system performance. Despite its widespread adoption, there is little empirical evidence on how it works, the challenges surrounding its implementation, its impact, and the preconditions for it to function effectively, particularly in low- and middle-income settings. The objective of this chapter is to analyze critically the extent to which purchasing could be, and has been used strategically in China and to identify modifications that are needed for purchasing to be effective in assuring that the government's new funding for health care will result in efficient and effective health services. We present a conceptual framework for purchasing, which identifies three critical principal-agent relationships in purchasing. We draw on evidence from secondary data, results of other research studies, interviews, and the impact evaluation of a social experiment in rural China that explicitly used purchasing to improve quality and efficiency. This information is used to examine purchasing relationships in urban social health insurance (SHI), the rural medical insurance scheme, and purchasing of public health services. To date, use of strategic purchasing is limited in China. Both the urban and the rural health insurance schemes act as passive third-party payers, failing to take advantage of the opportunities to strengthen incentives to improve quality and efficiency. This may be because as government agencies, the extent to which the Ministries of Health and Labor and Social Security can act independently from provider interests, or act in the best interest of the population, is unclear. Other important challenges include ensuring adequate representation of the population's views and preferences and making better use of the leverage provided by purchasing to create appropriate provider incentives, through better integration of financing and improved coordination among purchasers. In designing purchasing arrangements, attention needs to be paid to all three principal-agent relationships. Successful purchasing appears to require mechanisms to mobilize and represent community preferences and more strategic contracting with providers. More research is needed to strengthen the evidence on which purchasing arrangements work, which do not work, and under what conditions different purchasing configurations can work most effectively.
ERIC Educational Resources Information Center
Serpa, Fernando A.
This report describes a 1998 consultation conducted to examine the impact of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 on legal immigrants and refugees in Rhode Island. The Personal Responsibility and Work Opportunity Act restricted access of documented immigrants to a wide range of government programs such as…
7 CFR 56.31 - Report of grading work.
Code of Federal Regulations, 2011 CFR
2011-01-01
... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF SHELL EGGS Grading of Shell Eggs Reports § 56.31 Report of grading work. Reports of grading work performed...
Patient Safety and Quality Improvement Act of 2005.
Fassett, William E
2006-05-01
To review Public Law (PL) 109-41-the Patient Safety and Quality Improvement Act of 2005 (PSQIA)-and summarize key medication error research that contributed to congressional recognition of the need for this legislation. Relevant publications related to medication error research, patient safety programs, and the legislative history of and commentary on PL 109-41, published in English, were identified by MEDLINE, PREMEDLINE, Thomas (Library of Congress), and Internet search engine-assisted searches using the terms healthcare quality, medication error, patient safety, PL 109-41, and quality improvement. Additional citations were identified from references cited in related publications. All relevant publications were reviewed. Summarization of the PSQIA was carried out by legal textual analysis. PL 109-41 provides privilege and confidentiality for patient safety work product (PSWP) developed for reporting to patient safety organizations (PSOs). It does not establish federal mandatory reporting of significant errors; rather, it relies on existing state reporting systems. The Act does not preempt stronger state protections for PSWP. The Agency for Healthcare Research and Quality is directed to certify PSOs and promote the establishment of a national network of patient safety databases. Whistleblower protection and penalties for unauthorized disclosure of PSWP are among its enforcement mechanisms. The Act protects clinicians who report minor errors to PSOs and protects the information from disclosure, but providers must increasingly embrace a culture of interdisciplinary concern for patient safety if this protection is to have real impact on patient care.
Scott, Charles L
2010-01-01
The Americans With Disabilities Act Amendments Act of 2008 (ADAAA) significantly modifies the 1990 Americans With Disabilities Act. As a result of this legislation, more Americans are likely to qualify as disabled and to be further protected from discrimination under the ADA. The ADAAA also effectively overturns key rulings in the U.S. Supreme Court cases of Sutton v. United Air Lines, Inc. and Toyota Motor Manufacturing v. Williams. This article summarizes important changes resulting from the ADAAA legislation that psychiatrists and psychologists must understand when evaluating ADA disability claims.
The national strategy for the physical protection of critical infrastructures and key assets
DOT National Transportation Integrated Search
2003-02-01
This document defines the road ahead for a core mission area identified in the President's National Strategy for Homeland Security-reducing the Nation's vulnerability to acts of terrorism by protecting our critical infrastructures and key assets from...
A framework for current public mental health care practice in South Africa.
Janse Van Rensburg, A B
2007-11-01
One of the main aims of the new Mental Health Care Act, Act No. 17 of 2002 (MHCA) is to promote the human rights of people with mental disabilities in South Africa. However, the upholding of these rights seems to be subject to the availability of resources. Chapter 2 of the MHCA clarifies the responsibility of the State to provide infrastructure and systems. Chapters 5, 6 and 7 of the Act define and regulate the different categories of mental health care users, clarify the procedures around these categories and spell out mental health practitioners' roles and responsibilities in this regard. Also according to the National Health Act No. 61 of 2003, the State remains the key role player in mental health care provision, being responsible for adequate mental health infrastructure and resource allocation. Due to "limited resources" practitioners however often work in environments where staff ratios may be fractional of what should be expected and in units of which the physical structure and security is totally inadequate. The interface between professional responsibility of clinical workers versus the inadequacy of clinical interventions resulting from infrastructure and staffing constraints needs to be defined. This paper considered recent legislation currently relevant to mental health care practice in order to delineate the legal, ethical and labour framework in which public sector mental health practitioners operate as state employees. These included the Mental Health Care Act, No.17 of 2002; the National Health Act, No. 61 of 2003 and the proposed Traditional Health Practitioners Act, No. 35 of 2004. Formal legal review of and advice on this legislation as it pertains to public sector mental health practitioners as state employees, is necessary and should form the basis of the principles and standards for care endorsed by organized mental health care practitioner groups such as the South African Society of Psychiatrists (SASOP).
14 CFR Appendix to Part 1274 - Listing of Exhibits
Code of Federal Regulations, 2010 CFR
2010-01-01
... laborer on the basis of a standard work week of 40 hours. Work in excess of the standard work week is... pay for all hours worked in excess of 40 hours in the work week. Section 107 of the Act is applicable... Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where applicable, all contracts awarded by...
ERIC Educational Resources Information Center
Wiberg, Mary
This digest consists of two brief articles. The lead article, "The School-to-Work Opportunities Act: An Opportunity To Serve All Students" (Mary Wiberg) tells how the STW Act differs from vocational education by expanding the traditional programs and reflecting the constructivist model of education reform and how STW meets the needs of…
Zolna, Mia R; Kavanaugh, Megan L; Hasstedt, Kinsey
Given the recent reforms in the United States health care system, including the passage and implementation of the Affordable Care Act, as well as anticipated upcoming changes to health care coverage, it is critical that publicly funded health care providers understand how to effectively work with their states' Medicaid programs and the private health insurance plans in their service areas to provide high-quality contraceptive care to the millions of women relying on services at these sites annually. We collected survey data from a nationally representative sample of 535 clinics providing family planning services that received Title X funding and conducted semistructured interviews with 23 administrators at a subsample of surveyed clinics to explore provider-reported experiences working with health plans and to identify barriers to, and practices that lead to, adequate reimbursement for services provided. Providers report that knowledgeable staff are crucial to securing contracts with both public and private insurance plan issuers, and that the contracts they secure often include coverage restrictions on methods or services clinics offer their clients. Good staff relationships with issuers are key to obtaining adequate and consistent reimbursement for all covered services. Providers are trying to understand how insurance programs in their area knit together. Regardless of how U.S. health policies and delivery systems may change in the coming years, it is imperative that publicly funded family planning centers continue to work with health plans and maximize their third-party revenue to provide services to those in need. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
Zolna, Mia R.; Kavanaugh, Megan L.; Hasstedt, Kinsey
2018-01-01
Introduction Given the recent reforms in the United States health care system, including the passage and implementation of the Affordable Care Act, as well as anticipated upcoming changes to health care coverage, it is critical that publicly funded health care providers understand how to effectively work with their states’ Medicaid programs and the private health insurance plans in their service areas to provide high-quality contraceptive care to the millions of women relying on services at these sites annually. Methods We collected survey data from a nationally representative sample of 535 clinics providing family planning services that received Title X funding and conducted semistructured interviews with 23 administrators at a subsample of surveyed clinics to explore provider-reported experiences working with health plans and to identify barriers to, and practices that lead to, adequate reimbursement for services provided. Results Providers report that knowledgeable staff are crucial to securing contracts with both public and private insurance plan issuers, and that the contracts they secure often include coverage restrictions on methods or services clinics offer their clients. Good staff relationships with issuers are key to obtaining adequate and consistent reimbursement for all covered services. Conclusions Providers are trying to understand how insurance programs in their area knit together. Regardless of how U.S. health policies and delivery systems may change in the coming years, it is imperative that publicly funded family planning centers continue to work with health plans and maximize their third-party revenue to provide services to those in need. PMID:29108987
Pingitore, V; Miriello, D; Drioli, E; Gugliuzza, A
2015-06-14
This work describes some single walled carboxylic carbon nanotubes with outstanding transport properties when assembled in a 3D microarray working like a humidity membrane-sensor and an adjustable moisture regulator. Combined nano-assembly approaches are used to build up a better quality pathway through which assisted-charge and mass transport synchronically takes place. The structure-electrical response relationship is found, while controllable and tunable donor-acceptor interactions established at material interfaces are regarded as key factors for the accomplishment of charge transportation, enhanced electrical responses and adjustable moisture exchange. Raman and infrared spectroscopy provides indications about the fine structural and chemical features of the hybrid-composite membranes, resulting in perfect agreement with related morphology and electrical properties. Enhanced and modular electrical response to changes in the surrounding atmosphere is concerned with doping events, while assisted moisture regulation is discussed in relation to swelling and hopping actions. The electro-activated hybrid-composite membrane proposed in this work can be regarded as an attractive 'sense-to-act' precursor for smart long-distance monitoring systems with capability to adapt itself and provide local comfortable microenvironments.
32 CFR Appendix A to Part 32 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-07-01
... Federal awarding agency. 4. Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where... hours. Work in excess of the standard work week is permissible provided that the worker is compensated... hours in the work week. Section 107 of the Act is applicable to construction work and provides that no...
40 CFR Appendix to Part 30 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-07-01
.... 4. Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where applicable, all contracts... week of 40 hours. Work in excess of the standard work week is permissible provided that the worker is... hours in the work week. Section 107 of the Act is applicable to construction work and provides that no...
45 CFR Appendix A to Part 74 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-10-01
... hours. Work in excess of the standard work week is permissible provided that the worker is compensated... hours in the work week. Section 107 of the Act is applicable to construction work and provides that no.... Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)— Where applicable, all contracts awarded...
2 CFR Appendix A to Part 215 - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-01-01
... hours. Work in excess of the standard work week is permissible provided that the worker is compensated... hours in the work week. Section 107 of the Act is applicable to construction work and provides that no.... Contract Work Hours and Safety Standards Act (40 U.S.C. 327-333)—Where applicable, all contracts awarded by...
Key Skills and Competencies. Symposium.
ERIC Educational Resources Information Center
2002
This document contains three papers on key skills and competencies and human resource development (HRD). "Career Related Competencies" (Marinka A.C.T. Kuijpers) reports findings from surveys completed by Dutch employees who identified these issues: self-reflection is more important than career control; age and gender influence attitude…
Gender influencers on work values of black adolescents.
Thomas, V G; Shields, L C
1987-01-01
Work values and key influencers of a sample of black male and female adolescents were examined. Results indicated that boys and girls valued both the intrinsic and extrinsic rewards of work; however, girls reported slighter stronger extrinsic values than did boys. In addition, the sexes reported differences in the importance of specific work values such as "making lots of money," and "doing important things." When naming a key influencer, respondents tended to cite a same-sex and race individual. Sex of one's key influencer was related to certain work values, with subjects reporting a male key influencer valuing "trying out one's own ideas" and "having a secure future" more than those reporting a female key influencer. The interaction of sex of subject and sex of key influencer was significant on one of the work value outcomes. Implications of these findings are considered.
Roberts, Llion A; Raastad, Truls; Markworth, James F; Figueiredo, Vandre C; Egner, Ingrid M; Shield, Anthony; Cameron-Smith, David; Coombes, Jeff S; Peake, Jonathan M
2015-01-01
Abstract We investigated functional, morphological and molecular adaptations to strength training exercise and cold water immersion (CWI) through two separate studies. In one study, 21 physically active men strength trained for 12 weeks (2 days per week), with either 10 min of CWI or active recovery (ACT) after each training session. Strength and muscle mass increased more in the ACT group than in the CWI group (P < 0.05). Isokinetic work (19%), type II muscle fibre cross-sectional area (17%) and the number of myonuclei per fibre (26%) increased in the ACT group (all P < 0.05), but not the CWI group. In another study, nine active men performed a bout of single-leg strength exercises on separate days, followed by CWI or ACT. Muscle biopsies were collected before and 2, 24 and 48 h after exercise. The number of satellite cells expressing neural cell adhesion molecule (NCAM) (10−30%) and paired box protein (Pax7) (20−50%) increased 24–48 h after exercise with ACT. The number of NCAM+ satellite cells increased 48 h after exercise with CWI. NCAM+- and Pax7+-positive satellite cell numbers were greater after ACT than after CWI (P < 0.05). Phosphorylation of p70S6 kinaseThr421/Ser424 increased after exercise in both conditions but was greater after ACT (P < 0.05). These data suggest that CWI attenuates the acute changes in satellite cell numbers and activity of kinases that regulate muscle hypertrophy, which may translate to smaller long-term training gains in muscle strength and hypertrophy. The use of CWI as a regular post-exercise recovery strategy should be reconsidered. Key points Cold water immersion is a popular strategy to recover from exercise. However, whether regular cold water immersion influences muscle adaptations to strength training is not well understood. We compared the effects of cold water immersion and active recovery on changes in muscle mass and strength after 12 weeks of strength training. We also examined the effects of these two treatments on hypertrophy signalling pathways and satellite cell activity in skeletal muscle after acute strength exercise. Cold water immersion attenuated long term gains in muscle mass and strength. It also blunted the activation of key proteins and satellite cells in skeletal muscle up to 2 days after strength exercise. Individuals who use strength training to improve athletic performance, recover from injury or maintain their health should therefore reconsider whether to use cold water immersion as an adjuvant to their training. PMID:26174323
Key Points in Learning Forward's Definition of Professional Development
ERIC Educational Resources Information Center
Journal of Staff Development, 2010
2010-01-01
This article provides Learning Forward's definition of professional development. Learning Forward is seeking legislative amendments to include its definition in the Elementary and Secondary Education Act as reauthorized by the No Child Left Behind Act of 2001. These amendments will clarify what practices qualify for federal, state, and district…
Alternative Teacher Preparation Programs. Title II News You Can Use
ERIC Educational Resources Information Center
Office of Postsecondary Education, US Department of Education, 2015
2015-01-01
Title II of the "Higher Education Act of 1965" ("HEA"), as amended in 2008 by the "Higher Education Opportunity Act," requires states to report annually on key elements of their teacher preparation programs and requirements for initial teacher credentialing, kindergarten through 12th grade. "Title II News You Can…
Accountability Issues to Watch under NCLB Waivers
ERIC Educational Resources Information Center
Kober, Nancy; Riddle, Wayne
2012-01-01
In September 2011, the Obama Administration invited states to apply for waivers of key requirements of the Elementary and Secondary Education Act (ESEA) as amended by the No Child Left Behind Act (NCLB). The Administration's waiver initiative offers states the flexibility to move away from the flawed provisions of NCLB, including several…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-08
... Collection: American Recovery and Reinvestment Act (ARRA), High Growth and Emerging Industries (HGEI) Grants... competitive grants for worker training and placement in high growth and emerging industries, which included... funded through GJIF, the Department is emphasizing two key workforce strategies that move participants...
Formula Feedback and Central Cities: The Case of the Comprehensive Employment and Training Act.
ERIC Educational Resources Information Center
Jones, E. Terrence; Phares, Donald
1978-01-01
This study critically examines the measurement of the Comprehesive Employment and Training Act's key allocation variable, unemployment. The analysis indicates (1) unemployment rates are higher than government estimates and (2) methods used to measure state and local umemployment have several weaknesses. (Author/RLV)
Count Me In: Resource Manual on Disabilities.
ERIC Educational Resources Information Center
Milota, Cathy; And Others
This resource guide presents general information about disabilities and summaries of relevant federal laws. A question-and-answer format is used to highlight key features of the Education for All Handicapped Children Act (Public Law 94-142, reauthorized in 1990 as the Individuals with Disabilities Education Act); Section 504 of the Rehabilitation…
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis.
Muhar, Matthias; Ebert, Anja; Neumann, Tobias; Umkehrer, Christian; Jude, Julian; Wieshofer, Corinna; Rescheneder, Philipp; Lipp, Jesse J; Herzog, Veronika A; Reichholf, Brian; Cisneros, David A; Hoffmann, Thomas; Schlapansky, Moritz F; Bhat, Pooja; von Haeseler, Arndt; Köcher, Thomas; Obenauf, Anna C; Popow, Johannes; Ameres, Stefan L; Zuber, Johannes
2018-05-18
Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq [thiol(SH)-linked alkylation for the metabolic sequencing of RNA], a method for direct quantification of newly synthesized messenger RNAs (mRNAs), with pharmacological and chemical-genetic perturbation in order to define regulatory functions of two transcriptional hubs in cancer, BRD4 and MYC, and to interrogate direct responses to BET bromodomain inhibitors (BETis). We found that BRD4 acts as general coactivator of RNA polymerase II-dependent transcription, which is broadly repressed upon high-dose BETi treatment. At doses triggering selective effects in leukemia, BETis deregulate a small set of hypersensitive targets including MYC. In contrast to BRD4, MYC primarily acts as a selective transcriptional activator controlling metabolic processes such as ribosome biogenesis and de novo purine synthesis. Our study establishes a simple and scalable strategy to identify direct transcriptional targets of any gene or pathway. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
A new method to evaluate human-robot system performance
NASA Technical Reports Server (NTRS)
Rodriguez, G.; Weisbin, C. R.
2003-01-01
One of the key issues in space exploration is that of deciding what space tasks are best done with humans, with robots, or a suitable combination of each. In general, human and robot skills are complementary. Humans provide as yet unmatched capabilities to perceive, think, and act when faced with anomalies and unforeseen events, but there can be huge potential risks to human safety in getting these benefits. Robots provide complementary skills in being able to work in extremely risky environments, but their ability to perceive, think, and act by themselves is currently not error-free, although these capabilities are continually improving with the emergence of new technologies. Substantial past experience validates these generally qualitative notions. However, there is a need for more rigorously systematic evaluation of human and robot roles, in order to optimize the design and performance of human-robot system architectures using well-defined performance evaluation metrics. This article summarizes a new analytical method to conduct such quantitative evaluations. While the article focuses on evaluating human-robot systems, the method is generally applicable to a much broader class of systems whose performance needs to be evaluated.
29 CFR 5.32 - Overtime payments.
Code of Federal Regulations, 2011 CFR
2011-07-01
... THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Interpretation of the Fringe Benefits Provisions of... Contract Work Hours and Safety Standards Act, and the Walsh-Healey Public Contracts Act whenever the... computed on a regular or basic rate of $3.00 an hour. However, in some cases a question of fact may be...
29 CFR 5.32 - Overtime payments.
Code of Federal Regulations, 2010 CFR
2010-07-01
... THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Interpretation of the Fringe Benefits Provisions of... Contract Work Hours and Safety Standards Act, and the Walsh-Healey Public Contracts Act whenever the... computed on a regular or basic rate of $3.00 an hour. However, in some cases a question of fact may be...
South African labour law and HIV / AIDS.
Smart, R; Strode, A
1999-01-01
This article contains five key pieces of labor legislation in South Africa, including one applying specifically to the mining industry which protect the rights of employees. These laws include: the Employment Equity Act, No. 55 of 1998; the Labour Relations Act, No. 66 of 1995; the Occupational Health and Safety Act, No. 85 of 1993; the Compensation for Occupational Injuries and Diseases Act No. 130 of 1993; the Mines Health and Safety Act, No. 29 of 1996; and the Basic Conditions of Employment Act, No. 75 of 1997. This paper further presents the Medical Schemes Act, No. 131 of 1998 and the protection of the right to privacy and dignity. Although HIV/AIDS was expressly referred to only in the Employment Equity Act, there are provisions in all the other Acts, which have relevance to HIV/AIDS.
NASA Astrophysics Data System (ADS)
Olmstead, Dean A.; Schertler, Ronald R.; Randall, Laura A.
1992-03-01
The Advanced Communications Technology Satellite (ACTS), now under development and scheduled for launch in early 1993, is the current focus of NASA's commercial communications satellite program. The full power of the key technologies on ACTS can only be realized if industry assumes an active role in the conduct of experiments and demonstrations. This paper discusses the current market-driven rationale behind the ACTS Experiments Program activities aimed at getting industry involved - a rationale that addresses industry concerns and responds to industry inputs.
14 CFR Appendix A to Subpart B of... - Contract Provisions
Code of Federal Regulations, 2010 CFR
2010-01-01
... suspected or reported violations to the NASA. 4. Contract Work Hours and Safety Standards Act (40 U.S.C. 327... laborer on the basis of a standard work week of 40 hours. Work in excess of the standard work week is... pay for all hours worked in excess of 40 hours in the work week. Section 107 of the Act is applicable...
Learning Competitive Intelligence from a Bunch of Screwballs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Troy Hiltbrand
Idaho National Laboratory is the Department of Energy’s (DOE) lead lab for nuclear energy research and is dedicated to supporting the advancement of missions in nuclear energy research, energy and environment, and national security. The laboratory is operated by Battelle Energy Alliance (BEA) and participates both independently and jointly with other labs in the support of work for the DOE and other government organizations. The Information Management department is a key support organization whose purpose is to enable the three key areas supporting the Laboratory mission, Nuclear Energy, National and Homeland Security, and Energy and Environment, are successful. The challengemore » that we face is having relevant information about what these key areas of the Laboratory are working on and how we can best support them in achieving overall mission success. In addition, one of the major challenges that they face comes with knowing their customers and their customer’s needs so that they can successfully execute on their mission. Technology Application Organizations today are dependent on understanding their customers and competitors so that they can respond accordingly, but this can be a difficult and vexing challenge. Customers do not always reveal all of their needs and competitors rarely come out and reveal what they are doing, but this does not mean that hints about their plans are not abundant in information that is readily available. The challenge has always been how to keep track of all that is happening and converting that into useful information. Taking the lead from the “Screwball Division” from World War II, we have the tools available to automate this process and start to mine the Internet to get clues of what our customers and competitors are actively working on. By looking at what is being said and relating that to what else is being said, we can build competitive intelligence and act upon this to further our organizational objectives.« less
Non-coding RNA networks in cancer.
Anastasiadou, Eleni; Jacob, Leni S; Slack, Frank J
2018-01-01
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the past decade has altered our perception of ncRNAs from 'junk' transcriptional products to functional regulatory molecules that mediate cellular processes including chromatin remodelling, transcription, post-transcriptional modifications and signal transduction. The networks in which ncRNAs engage can influence numerous molecular targets to drive specific cell biological responses and fates. Consequently, ncRNAs act as key regulators of physiological programmes in developmental and disease contexts. Particularly relevant in cancer, ncRNAs have been identified as oncogenic drivers and tumour suppressors in every major cancer type. Thus, a deeper understanding of the complex networks of interactions that ncRNAs coordinate would provide a unique opportunity to design better therapeutic interventions.
School-to-Work Risk Management.
ERIC Educational Resources Information Center
Voorheis, Greg; Meyer, Gregg; Van Houten, June
This paper examines risk and liability issues related to school to work (STW) programs. With the passage of the federal School-to-Work Opportunities Act of 1994, the distance between the school and the world of work is diminishing. The Act's requirement that students, schools, and employers become part of an integrated learning process brings the…
Code of Federal Regulations, 2010 CFR
2010-10-01
... NATIVE EMPLOYMENT WORKS (NEW) PROGRAM NEW Program Funding § 287.35 What grant amounts are available under the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) for the NEW... Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) for the NEW Program? 287...
[Key content and formulation of national Chinese materia medica resources survey at county level].
Lu, Jian-Wei; Zhang, Xiao-Bo; Li, Hai-Tao; Guo, Lan-Ping; Zhao, Run-Huai; Zhang, Ben-Gang; Sun, Li-Ying; Huang, Lu-Qi
2013-08-01
According to National Census for Water, National Population Census, National Land and Resources Survey, and work experience of experimental measures for national Chinese materia medica resources(CMMR) survey,the national CMMR survey at the county level is the key point of whole survey, that includes organization and management, field survey, sorting data three key links. Organization and management works of national CMMR survey needs to finish four key contents, there are definite goals and tasks, practicable crew, preparation directory, and security assurance. Field survey works of the national CMMR survey needs to finish five key contents, there are preparation works for field survey, the choice of the key survey area (samples), fill in the questionnaire, video data collection, specimen and other physical collection. Sorting data works of the national CMMR survey needs to finish tree key contents, there are data, specimen and census results.
Request for Correction 15003 - Information Quality Act request for Correction of the TSCA Work Plan
This RFC concerns the Information Quality Act request for correction of the TSCA Work Plan for Chemical Assessments: 20154 Update and the TSCA Work Plan Chemicals: Methods Document (February 2012) regarding assessment of phthalic anhydride
Sunk cost and work ethic effects reflect suboptimal choice between different work requirements.
Magalhães, Paula; White, K Geoffrey
2013-03-01
We investigated suboptimal choice between different work requirements in pigeons (Columba livia), namely the sunk cost effect, an irrational tendency to persist with an initial investment, despite the availability of a better option. Pigeons chose between two keys, one with a fixed work requirement to food of 20 pecks (left key), and the other with a work requirement to food which varied across conditions (center key). On some trials within each session, such choices were preceded by an investment of 35 pecks on the center key, whereas on others they were not. On choice trials preceded by the investment, the pigeons tended to stay and complete the schedule associated with the center key, even when the number of pecks to obtain reward was greater than for the concurrently available left key. This result indicates that pigeons, like humans, commit the sunk cost effect. With higher work requirements, this preference was extended to trials where there was no initial investment, so an overall preference for the key associated with more work was evident, consistent with the work ethic effect. We conclude that a more general work ethic effect is amplified by the effect of the prior investment, that is, the sunk cost effect. Copyright © 2013 Elsevier B.V. All rights reserved.
22 CFR Appendix A to Part 145 - Clauses for Contracts and Small Purchases Awarded by Recipient
Code of Federal Regulations, 2010 CFR
2010-04-01
... suspected or reported violations to the Department. 4. Contract Work Hours and Safety Standards Act (40 U.S... mechanic and laborer on the basis of a standard work week of 40 hours. Work in excess of the standard work... basic rate of pay for all hours worked in excess of 40 hours in the work week. Section 107 of the Act is...
Evaluation of the durability of 3D printed keys produced by computational processing of image data
NASA Astrophysics Data System (ADS)
Straub, Jeremy; Kerlin, Scott
2016-05-01
Possession of a working 3D printed key can, for most practical purposes, convince observers that an illicit attempt to gain premises access is authorized. This paper seeks to assess three things. First, work has been performed to determine how easily the data for making models of keys can be obtained through manual measurement. It then presents work done to create a model of the key and determine how easy key modeling could be (particularly after a first key of a given key `blank' has been made). Finally, it seeks to assess the durability of the keys produced using 3D printing.
Joe L. Kincheloe: Genies and Wishes--A Review of "Key Works in Critical Pedagogy"
ERIC Educational Resources Information Center
Ali-Khan, Carolyne; Siry, Christina
2012-01-01
We review "Key Works in Critical Pedagogy: Joe L. Kincheloe" edited by Kecia Hayes, Shirley R. Steinberg and Kenneth Tobin, which gathers the seminal works of Joe. L. Kincheloe and pairs them with contemporary scholars who respond to and push forward Kincheloe's work. The chapters of "Key Works in Critical Pedagogy" are arranged to begin with…
18 CFR 367.1070 - Account 107, Construction work in progress.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 107, Construction work in progress. 367.1070 Section 367.1070 Conservation of Power and Water Resources FEDERAL... ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE...
29 CFR 780.724 - Work exempt under another section of the Act.
Code of Federal Regulations, 2014 CFR
2014-07-01
... STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption From Overtime Pay... is exempt only from the overtime pay provisions under another section, the employee is exempt that..., attention is directed to another exemption in the Act which relates to work in grain elevators, which may...
29 CFR 780.724 - Work exempt under another section of the Act.
Code of Federal Regulations, 2012 CFR
2012-07-01
... STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption From Overtime Pay... is exempt only from the overtime pay provisions under another section, the employee is exempt that..., attention is directed to another exemption in the Act which relates to work in grain elevators, which may...
29 CFR 780.724 - Work exempt under another section of the Act.
Code of Federal Regulations, 2013 CFR
2013-07-01
... STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption From Overtime Pay... is exempt only from the overtime pay provisions under another section, the employee is exempt that..., attention is directed to another exemption in the Act which relates to work in grain elevators, which may...
29 CFR 780.724 - Work exempt under another section of the Act.
Code of Federal Regulations, 2011 CFR
2011-07-01
... STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption From Overtime Pay... is exempt only from the overtime pay provisions under another section, the employee is exempt that..., attention is directed to another exemption in the Act which relates to work in grain elevators, which may...
29 CFR 780.724 - Work exempt under another section of the Act.
Code of Federal Regulations, 2010 CFR
2010-07-01
... STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption From Overtime Pay... is exempt only from the overtime pay provisions under another section, the employee is exempt that..., attention is directed to another exemption in the Act which relates to work in grain elevators, which may...
Jung, Minsoo
2017-01-01
This study investigated the effect of implementing the act of prohibition on sex trafficking (PST) on sexually transmitted disease (STD) infections among South Korean female sex workers (FSWs) working at prostitution blocks. Research data were collected twice through the Korean government-sanctioned survey for female sex workers (1st wave = 1,083; 2nd wave = 926). We examined the associations among health behavior, working conditions, and the effect of PST act via hierarchical logistic regression analyses using propensity score matching. After adjusted covariates, the risk probability was 0.288 times lower among FSWs who had remained in prostitute blocks after the PST act enforcement compared to FSWs who had worked before the PST. Similarly, the risk probability for a gonorrhea infection was 0.219 times lower among FSWs who had remained in prostitute blocks after the PST act compared to FSWs who had worked before the PST. Therefore, this study showed that, besides already known factors, the implementation and establishment of the PST Act was a strong factor that suppressed STD infections among FSWs.
2017-01-01
This study investigated the effect of implementing the act of prohibition on sex trafficking (PST) on sexually transmitted disease (STD) infections among South Korean female sex workers (FSWs) working at prostitution blocks. Research data were collected twice through the Korean government-sanctioned survey for female sex workers (1st wave = 1,083; 2nd wave = 926). We examined the associations among health behavior, working conditions, and the effect of PST act via hierarchical logistic regression analyses using propensity score matching. After adjusted covariates, the risk probability was 0.288 times lower among FSWs who had remained in prostitute blocks after the PST act enforcement compared to FSWs who had worked before the PST. Similarly, the risk probability for a gonorrhea infection was 0.219 times lower among FSWs who had remained in prostitute blocks after the PST act compared to FSWs who had worked before the PST. Therefore, this study showed that, besides already known factors, the implementation and establishment of the PST Act was a strong factor that suppressed STD infections among FSWs. PMID:28793341
NASA Astrophysics Data System (ADS)
Gaunaa, Mac; Heinz, Joachim; Skrzypiński, Witold
2016-09-01
The crossflow principle is one of the key elements used in engineering models for prediction of the aerodynamic loads on wind turbine blades in standstill or blade installation situations, where the flow direction relative to the wind turbine blade has a component in the direction of the blade span direction. In the present work, the performance of the crossflow principle is assessed on the DTU 10MW reference blade using extensive 3D CFD calculations. Analysis of the computational results shows that there is only a relatively narrow region in which the crossflow principle describes the aerodynamic loading well. In some conditions the deviation of the predicted loadings can be quite significant, having a large influence on for instance the integral aerodynamic moments around the blade centre of mass; which is very important for single blade installation applications. The main features of these deviations, however, have a systematic behaviour on all force components, which in this paper is employed to formulate the first version of an engineering correction method to the crossflow principle applicable for wind turbine blades. The new correction model improves the agreement with CFD results for the key aerodynamic loads in crossflow situations. The general validity of this model for other blade shapes should be investigated in subsequent works.
ASR5 is involved in the regulation of miRNA expression in rice.
Neto, Lauro Bücker; Arenhart, Rafael Augusto; de Oliveira, Luiz Felipe Valter; de Lima, Júlio Cesar; Bodanese-Zanettini, Maria Helena; Margis, Rogerio; Margis-Pinheiro, Márcia
2015-11-01
The work describes an ASR knockdown transcriptomic analysis by deep sequencing of rice root seedlings and the transactivation of ASR cis-acting elements in the upstream region of a MIR gene. MicroRNAs are key regulators of gene expression that guide post-transcriptional control of plant development and responses to environmental stresses. ASR (ABA, Stress and Ripening) proteins are plant-specific transcription factors with key roles in different biological processes. In rice, ASR proteins have been suggested to participate in the regulation of stress response genes. This work describes the transcriptomic analysis by deep sequencing two libraries, comparing miRNA abundance from the roots of transgenic ASR5 knockdown rice seedlings with that of the roots of wild-type non-transformed rice seedlings. Members of 59 miRNA families were detected, and 276 mature miRNAs were identified. Our analysis detected 112 miRNAs that were differentially expressed between the two libraries. A predicted inverse correlation between miR167abc and its target gene (LOC_Os07g29820) was confirmed using RT-qPCR. Protoplast transactivation assays showed that ASR5 is able to recognize binding sites upstream of the MIR167a gene and drive its expression in vivo. Together, our data establish a comparative study of miRNAome profiles and is the first study to suggest the involvement of ASR proteins in miRNA gene regulation.
Lakshminarayana, Indumathy; Wall, David; Bindal, Taruna
2014-01-01
Summary Objectives To look at why a regional cohort of UK doctors chose a paediatric career and to ascertain views on their career near the end of training year one. Design A 20-item questionnaire was sent to all new regional paediatric specialty trainees. Three focus groups were held with trainees near the end of year one to elicit key themes. Setting West Midlands Deanery, UK Participants Twenty-nine new regional paediatric specialty trainees in year one completed the questionnaire. A total of 15 trainees participated in the focus groups near the end of year one training. Main outcome measures Reasons for choosing a paediatric career and factors which further influence career choice for trainees during their first specialty training year. Results Key influencing factors for choosing paediatrics were enjoying working with children and positive undergraduate experience of the specialty. All trainees had paediatrics as their first choice specialty and undertook a paediatric Foundation post. Near the end of year one, doubts were cast on career aspirations due to seeing middle grade colleagues struggling with work–life balance and a growing feeling that family came first. Conclusions Senior trainees need to be aware that they act as powerful role models for their more junior colleagues and therefore have an influential role on how juniors perceive a paediatric career. Family friendly flexible working patterns in paediatrics are vital to retain junior trainees. All paediatric staff are role models and need to be enthusiastic, keen to teach and to promote a positive working environment. PMID:25352989
Special Education Law: Illustrative Basics and Nuances of Key IDEA Components
ERIC Educational Resources Information Center
Zirkel, Perry A.
2015-01-01
Intended as professional development for both new and experienced special educators, this article provides both the basic requirements and nuanced issues for foundational, successive, and overlapping key components under the Individuals With Disabilities Education Act (IDEA): (a) child find, (b) eligibility, and (c) free appropriate public…
Code of Federal Regulations, 2011 CFR
2011-07-01
... Stabilization Act of 2008. Key individual means an individual providing services to a private sector entity who... agency agreement between a private sector entity and the Treasury for services under the TARP, other than... arrangement with the Treasury. For purposes of the definition of key individual, the words “personally and...
75 FR 36642 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-28
... relating to the issue, return, and accountability of keys to secure areas. Records may contain name, Social... disposing of records in the system: Storage: Paper records in file folders and electronic storage media. Retrievability: By name, Social Security Number (SSN), key number, personal identification number (PIN), Magnetic...
25 CFR 522.2 - Submission requirements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... shall submit to the Chairman all of the following information with a request for approval of a class II... background investigations on key employees and primary management officials and to ensure that key employees and primary management officials are notified of their rights under the Privacy Act as specified in...
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis
Smith, Martyn T.; Guyton, Kathryn Z.; Gibbons, Catherine F.; Fritz, Jason M.; Portier, Christopher J.; Rusyn, Ivan; DeMarini, David M.; Caldwell, Jane C.; Kavlock, Robert J.; Lambert, Paul F.; Hecht, Stephen S.; Bucher, John R.; Stewart, Bernard W.; Baan, Robert A.; Cogliano, Vincent J.; Straif, Kurt
2015-01-01
Background: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A–F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. Objectives and Methods: IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. Discussion: These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. Conclusion: We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA’s Integrated Risk Information System Program and the U.S. National Toxicology Program. Citation: Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health Perspect 124:713–721; http://dx.doi.org/10.1289/ehp.1509912 PMID:26600562
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.
Smith, Martyn T; Guyton, Kathryn Z; Gibbons, Catherine F; Fritz, Jason M; Portier, Christopher J; Rusyn, Ivan; DeMarini, David M; Caldwell, Jane C; Kavlock, Robert J; Lambert, Paul F; Hecht, Stephen S; Bucher, John R; Stewart, Bernard W; Baan, Robert A; Cogliano, Vincent J; Straif, Kurt
2016-06-01
A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A-F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA's Integrated Risk Information System Program and the U.S. National Toxicology Program. Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health Perspect 124:713-721; http://dx.doi.org/10.1289/ehp.1509912.
Enrollment in Teacher Preparation Programs. Title II News You Can Use
ERIC Educational Resources Information Center
Office of Postsecondary Education, US Department of Education, 2015
2015-01-01
Title II of the "Higher Education Act of 1965" ("HEA"), as amended in 2008 by the "Higher Education Opportunity Act," requires states to report annually on key elements of their teacher preparation programs and requirements for initial teacher credentialing, kindergarten through 12th grade. "Title II News You Can…
The Diagnosis of LD in English Learners: Is It Nondiscriminatory?
ERIC Educational Resources Information Center
Figueroa, Richard A.; Newsome, Patricia
2006-01-01
This study examined the operationalization of one of the key reforms initiated by the Education for All Handicapped Children Act of 1975 (U.S. Congress, 1975) and continued through the 2004 reauthorization of the Individuals with Disabilities Education Act (U.S. Congress, 2004)--namely, nondiscriminatory assessment. The original and current…
Building Bridges with Families: Honoring the Mandates of IDEIA
ERIC Educational Resources Information Center
Coots, Jennifer J.
2007-01-01
Parent participation has been one of the key principles of the Individuals with Disabilities Education Improvement Act (IDEIA) since it was first authorized in 1975 as the Education for All Handicapped Children Act (EAHCA) and has continued through the most recent reauthorization in 2004. Parents of children with disabilities have decision making…
Factors Influencing Improved Student Achievement in Virginia
ERIC Educational Resources Information Center
Linehan, Patrick D.
2012-01-01
At the beginning of the last decade, Congress passed and President George W. Bush signed the No Child Left Behind (NCLB) Act of 2002. Key provisions of this act focused on holding schools accountable to ensure that all students met state established standards. In Virginia, the state Standards of Learning (SOL) assessments form the basis of…
Creating Safe Schools: Roles and Challenges, a Federal Perspective.
ERIC Educational Resources Information Center
Modzeleski, William
1996-01-01
Presents an overview of the Safe and Drug-Free Schools and Communities Act, a key federal program that provides funding directly to states and local educational agencies to facilitate drug and violence prevention programs. The Gun-Free Schools Act is also examined, and the major challenges communities face in correcting school safety problems are…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-15
... FURTHER INFORMATION CONTACT: For general questions please contact: Emily Andrew (703-235-2182), Privacy...: Background In accordance with the Privacy Act of 1974, 5 U.S.C. 552a, the Department of Homeland Security... Nation's 18 critical infrastructures and key resources (CIKR) sectors during normal operations and...
Cole, Donna M; Thomas, Dawna Marie; Field, Kelsi; Wool, Amelia; Lipiner, Taryn; Massenberg, Natalie; Guthrie, Barbara J
2017-11-09
Past drug epidemics have disproportionately criminalized drug addiction among African Americans, leading to disparate health outcomes, increased rates of HIV/AIDS, and mass incarceration. Conversely, the current opioid addiction crisis in the USA focuses primarily on white communities and is being addressed as a public health problem. The 21st Century Cures Act has the potential to reduce racial health disparities in the criminal justice system through the Act's public health approach to addiction and mental health issues. The 21st Century Cures Act is a progressive step in the right direction; however, given the historical context of segregation and the criminalization of drug addiction among African Americans, the goals of health equity are at risk of being compromised. This paper discusses the implications of this landmark legislation and its potential to decrease racial health disparities, highlighting the importance of ensuring that access to treatment and alternatives to incarceration must include communities of color. In this paper, the authors explain the key components of the 21st Century Cures Act that are specific to criminal justice reform, including a key objective, which is treatment over incarceration. We suggest that without proper attention to how, and where, funding mechanisms are distributed, the 21st Century Cures Act has the potential to increase racial health disparities rather than alleviate them.
Poteat, Tonia; Diouf, Daouda; Drame, Fatou Maria; Ndaw, Marieme; Traore, Cheikh; Dhaliwal, Mandeep; Beyrer, Chris; Baral, Stefan
2011-01-01
Men who have sex with men (MSM) are at high risk for HIV in Senegal, with a prevalence of 21.5%. In December 2008, nine male HIV prevention workers were imprisoned for “acts against nature” prohibited by Senegalese law. This qualitative study assessed the impact of these arrests on HIV prevention efforts. A purposive sample of MSM in six regions of Senegal was recruited by network referral. 26 in-depth interviews (IDIs) and 6 focus group discussions (FGDs) were conducted in July–August 2009. 14 key informants were also interviewed. All participants reported pervasive fear and hiding among MSM as a result of the December 2008 arrests and publicity. Service providers suspended HIV prevention work with MSM out of fear for their own safety. Those who continued to provide services noticed a sharp decline in MSM participation. An effective response to the HIV epidemic in Senegal should include active work to decrease enforcement of this law. PMID:22194906
Safety climate and culture: Integrating psychological and systems perspectives.
Casey, Tristan; Griffin, Mark A; Flatau Harrison, Huw; Neal, Andrew
2017-07-01
Safety climate research has reached a mature stage of development, with a number of meta-analyses demonstrating the link between safety climate and safety outcomes. More recently, there has been interest from systems theorists in integrating the concept of safety culture and to a lesser extent, safety climate into systems-based models of organizational safety. Such models represent a theoretical and practical development of the safety climate concept by positioning climate as part of a dynamic work system in which perceptions of safety act to constrain and shape employee behavior. We propose safety climate and safety culture constitute part of the enabling capitals through which organizations build safety capability. We discuss how organizations can deploy different configurations of enabling capital to exert control over work systems and maintain safe and productive performance. We outline 4 key strategies through which organizations to reconcile the system control problems of promotion versus prevention, and stability versus flexibility. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Stressful incidents of physical violence against emergency nurses.
Gillespie, Gordon Lee; Gates, Donna M; Berry, Peggy
2013-01-31
Physical violence against nurses has become an endemic problem affecting nurses in all settings. The purpose of this study was to describe acts of physical violence against emergency nurses perceived as stressful using a qualitative descriptive design with a national sample of emergency nurses. The guiding conceptual model for the study was the Ecological Occupational Health Model of Workplace Assault. Narrative accounts of physical violence were analyzed using a constant comparative analysis method. Key findings included risks related to employee, workplace, and aggressor factors, and descriptions of physical violence. Discussion of the study findings suggests that efforts to prevent violence and promote workplace safety need to focus on designing work environments that allow for the quick egress of employees, establishing and consistently enforcing policies aimed at violence prevention, and maintaining positive working relationships with security officers. While patients with mental health or substance use complaints are deemed most likely to commit physical violence, they are not the only patients to become violent. Risk reduction efforts should target all patients and visitors.
Tailoring of the thermomechanical performance of VO2 nanowire bimorph actuators by ion implantation
NASA Astrophysics Data System (ADS)
Karl, H.; Peyinghaus, S. C.
2015-12-01
Vanadium dioxide VO2 nanowire bimorph actuators work on the basis of the large abrupt length change at the metal-insulator phase transition (MIT). A key parameter for the bimorph performance and efficiency is the bending curvature and the width of the temperature hysteresis of the MIT which is inherently large for single domain VO2 metal side coated nanowires. In this work we present single-clamped Ir side coated VO2 bimorphs which show unprecedented high bending curvatures of up to 105 m-1 and new type of side ion-implanted VO2 nanowire bimorph actuators with a nearly completely suppressed temperature hysteresis. It is assumed that ion-beam induced radiation defects in the VO2 crystal structure act as nucleation sites for the MIT. Moreover it will be shown that mechanical strain intentionally built-in during VO2 nanowire bimorph fabrication allows to direct phase transformation via a strain stabilized metastable phase and thus allows to control bending response on temperature change.
Community-company relations in gold mining in Ghana.
Garvin, Theresa; McGee, Tara K; Smoyer-Tomic, Karen E; Aubynn, Emmanuel Ato
2009-01-01
As a result of Structural Adjustment Programme from the 1980s, many developing countries have experienced an increase in resource extraction activities by international and transnational corporations. The work reported here examines the perceived impacts of gold mining at the community level in the Wassa West District of Ghana, Africa and discusses those perceived impacts in the context of globalization processes and growing multinational corporate interest in Corporate Social Responsibility (CSR). Interview data compared community members' perceptions with those of company representatives in three communities. The results indicate that communities held companies responsible for a series of economic, social, and environmental changes. While recognizing some of the benefits brought by the mines, communities felt that the companies did not live up to their responsibility to support local development. Companies responded by denying, dismissing concerns, or shifting blame. Findings from this work show that lack of engagement and action by government agencies at all levels resulted in companies acting in a surrogate governmental capacity. In such situations, managing expectations is key to community-company relations.
Red, purple and pink: the colors of diffusion on pinterest.
Bakhshi, Saeideh; Gilbert, Eric
2015-01-01
Many lab studies have shown that colors can evoke powerful emotions and impact human behavior. Might these phenomena drive how we act online? A key research challenge for image-sharing communities is uncovering the mechanisms by which content spreads through the community. In this paper, we investigate whether there is link between color and diffusion. Drawing on a corpus of one million images crawled from Pinterest, we find that color significantly impacts the diffusion of images and adoption of content on image sharing communities such as Pinterest, even after partially controlling for network structure and activity. Specifically, Red, Purple and pink seem to promote diffusion, while Green, Blue, Black and Yellow suppress it. To our knowledge, our study is the first to investigate how colors relate to online user behavior. In addition to contributing to the research conversation surrounding diffusion, these findings suggest future work using sophisticated computer vision techniques. We conclude with a discussion on the theoretical, practical and design implications suggested by this work-e.g. design of engaging image filters.
Refining the aggregate exposure pathway.
Tan, Yu-Mei; Leonard, Jeremy A; Edwards, Stephen; Teeguarden, Justin; Egeghy, Peter
2018-03-01
Advancements in measurement technologies and modeling capabilities continue to result in an abundance of exposure information, adding to that currently in existence. However, fragmentation within the exposure science community acts as an obstacle for realizing the vision set forth in the National Research Council's report on Exposure Science in the 21 st century to consider exposures from source to dose, on multiple levels of integration, and to multiple stressors. The concept of an Aggregate Exposure Pathway (AEP) was proposed as a framework for organizing and integrating diverse exposure information that exists across numerous repositories and among multiple scientific fields. A workshop held in May 2016 followed introduction of the AEP concept, allowing members of the exposure science community to provide extensive evaluation and feedback regarding the framework's structure, key components, and applications. The current work briefly introduces topics discussed at the workshop and attempts to address key challenges involved in refining this framework. The resulting evolution in the AEP framework's features allows for facilitating acquisition, integration, organization, and transparent application and communication of exposure knowledge in a manner that is independent of its ultimate use, thereby enabling reuse of such information in many applications.
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.
Wertheimer, Tobias; Velardi, Enrico; Tsai, Jennifer; Cooper, Kirsten; Xiao, Shiyun; Kloss, Christopher C; Ottmüller, Katja J; Mokhtari, Zeinab; Brede, Christian; deRoos, Paul; Kinsella, Sinéad; Palikuqi, Brisa; Ginsberg, Michael; Young, Lauren F; Kreines, Fabiana; Lieberman, Sophia R; Lazrak, Amina; Guo, Peipei; Malard, Florent; Smith, Odette M; Shono, Yusuke; Jenq, Robert R; Hanash, Alan M; Nolan, Daniel J; Butler, Jason M; Beilhack, Andreas; Manley, Nancy R; Rafii, Shahin; Dudakov, Jarrod A; van den Brink, Marcel R M
2018-01-12
The thymus is not only extremely sensitive to damage but also has a remarkable ability to repair itself. However, the mechanisms underlying this endogenous regeneration remain poorly understood, and this capacity diminishes considerably with age. We show that thymic endothelial cells (ECs) comprise a critical pathway of regeneration via their production of bone morphogenetic protein 4 (BMP4) ECs increased their production of BMP4 after thymic damage, and abrogating BMP4 signaling or production by either pharmacologic or genetic inhibition impaired thymic repair. EC-derived BMP4 acted on thymic epithelial cells (TECs) to increase their expression of Foxn1 , a key transcription factor involved in TEC development, maintenance, and regeneration, and its downstream targets such as Dll4 , a key mediator of thymocyte development and regeneration. These studies demonstrate the importance of the BMP4 pathway in endogenous tissue regeneration and offer a potential clinical approach to enhance T cell immunity. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
NASA Astrophysics Data System (ADS)
Hosokawa, Shinya; Pilgrim, Wolf-Christian; Höhle, Astrid; Szubrin, Daniel; Boudet, Nathalie; Bérar, Jean-François; Maruyama, Kenji
2012-04-01
Laser-induced crystalline-amorphous phase change of Ge-Sb-Te alloys is the key mechanism enabling the fast and stable writing/erasing processes in rewritable optical storage devices, such as digital versatile disk (DVD) or blu-ray disk. Although the structural information in the amorphous phase is essential for clarifying this fast process, as well as long lasting stabilities of both the phases, experimental works were mostly limited to the short-range order by x ray absorption fine structure. Here we show both the short and intermediate-range atomic structures of amorphous DVD material, Ge2Sb2Te5 (GST), investigated by a combination of anomalous x ray scattering and reverse Monte Carlo modeling. From the obtained atomic configurations of amorphous GST, we have found that the Sb atoms and half of the Ge atoms play roles in the fast phase change process of order-disorder transition, while the remaining Ge atoms act for the proper activation energy of barriers between the amorphous and crystalline phases.
Microorganisms: Good or Evil, MIRRI Provides Biosecurity Awareness.
Smith, David; Martin, Dunja; Novossiolova, Tatyana
2017-03-01
The life-science community is a key stakeholder in the effort to ensure that the advances in biotechnology are not misused. Unfortunately, to date, the engagement of life scientists with issues of biosecurity has been limited. Microorganisms have been harnessed for the benefit of humankind but in the wrong hands could be used in direct or indirect acts against humans, livestock, crops, food, water infrastructure and other economically valuable entities. The Microbial Resources Research Infrastructure in its preparatory phase has addressed the topic implementing a code of conduct as part of its programme of prevention of malicious use and continues to work with the international community to raise awareness of best practice to avoid misuse of microorganisms. Biosecurity has become a major concern for several countries creating numerous activities to put in place counter measures, risk assessment, legislation and emergency response. The goal is to implement measures to protect us against malicious use of microorganisms, their products, information and technology transfer. Through this paper, we wish to discuss some of the activities that are underway, mention key educational tools and provide scientists with information on addressing biosecurity issues.
NASA Astrophysics Data System (ADS)
Or, Dani
2017-04-01
It may seem peculiar that John Dalton known primarily for his pioneering contributions to chemistry with the development of gas laws and modern atomic theory is somehow associated with hydrology. Dalton conducted some of earliest and definitive experiments and analyses to deduce regional water balance (1799) and subsequently expanded into "Essay on Evaporation" in 1802 maintaining keen interest in hydrometeorology throughout his adult life. A striking aspect of Dalton's pioneering work is the conviction in the generality of the laws of nature - in the conclusion of his 1799 water balance study he writes: "I think we may fairly conclude - that the rain and dew of this country are equivalent to the quantity of water carried off by evaporation and rivers", Dalton then adds "and as nature acts upon general laws, we ought to infer that it must be the case in every other country, till the contrary is proved". The presentation will trace key steps in evaporation research inspired by Dalton's vision and motivated by historical and contemporary discoveries of this key process central to hydrology, climate, and life on Earth.
ERIC Educational Resources Information Center
Jones-Brown, Delores; Mahoney, Jacqueline
2001-01-01
Though New York City's welfare reform act claims to emphasize personal responsibility, its design diminishes the possibility of sustained, meaningful employment or long-term economic stability for substantial numbers of Temporary Assistance for Needy Family recipients. By focusing on gaining employment, the act ignores well-established avenues to…
Department of Energy Recovery Act Investment in Biomass Technologies
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
2010-11-01
The American Recovery and Reinvestment Act of 2009 (Recovery Act) provided more than $36 billion to the Department of Energy (DOE) to accelerate work on existing projects, undertake new and transformative research, and deploy clean energy technologies across the nation. Of this funding, $1029 million is supporting innovative work to advance biomass research, development, demonstration, and deployment.
Purines and Neuronal Excitability: Links to the Ketogenic Diet
Masino, SA; Kawamura, M; Ruskin, DN; Geiger, JD; Boison, D
2011-01-01
ATP and adenosine are purines that play dual roles in cell metabolism and neuronal signaling. Acting at the A1 receptor (A1R) subtype, adenosine acts directly on neurons to inhibit excitability and is a powerful endogenous neuroprotective and anticonvulsant molecule. Previous research showed an increase in ATP and other cell energy parameters when an animal is administered a ketogenic diet, an established metabolic therapy to reduce epileptic seizures, but the relationship among purines, neuronal excitability and the ketogenic diet was unclear. Recent work in vivo and in vitro tested the specific hypothesis that adenosine acting at A1Rs is a key mechanism underlying the success of ketogenic diet therapy and yielded direct evidence linking A1Rs to the antiepileptic effects of a ketogenic diet. Specifically, an in vitro mimic of a ketogenic diet revealed an A1R-dependent metabolic autocrine hyperpolarization of hippocampal neurons. In parallel, applying the ketogenic diet in vivo to transgenic mouse models with spontaneous electrographic seizures revealed that intact A1Rs are necessary for the seizure-suppressing effects of the diet. This is the first direct in vivo evidence linking A1Rs to the antiepileptic effects of a ketogenic diet. Other predictions of the relationship between purines and the ketogenic diet are discussed. Taken together, recent research on the role of purines may offer new opportunities for metabolic therapy and insight into its underlying mechanisms. PMID:21880467
The Canadian Cannabis Act legalizes and regulates recreational cannabis use in 2018.
Cox, Chelsea
2018-03-01
Canada is on the cusp of an unprecedented change in its governmental approach to recreational cannabis consumption. By July of 2018 the country will legalize and regulate recreational cannabis use across the country via the implementation of the Cannabis Act, representing the second country in the world and the first in North America to do so. With almost half of Canadians having admitted to using the drug illegally, this change in policy has been long advocated. While medical cannabis has been legal since 2001 this represents the first time in recent history that recreational cannabis will be legal on a federal level. As the country moves away from criminal prohibition into a framework centered on harm minimization and public health and safety, the policy specifics are being worked out by a variety of stakeholders. With limited peer-reviewed research and similar regulatory schemes to shape the Cannabis Act off of, Canada is entering unchartered territory. As other countries around the world struggle with illegal cannabis consumption, the Canadian example and novel regulatory scheme could prove a useful guiding tool for future policy in other jurisdictions. The following paper discusses key areas to watch and a brief intro of how Canada got to where it is and the foundational need for a shift in policy. Copyright © 2018 Elsevier B.V. All rights reserved.
Improving patient handover between teams using a business improvement model: PDSA cycle.
Luther, Vishal; Hammersley, Daniel; Chekairi, Ahmed
2014-01-01
Medical admission units are continuously under pressure to move patients off the unit to outlying medical wards and allow for new admissions. In a typical district general hospital, doctors working in these medical wards reported that, on average, three patients each week arrived from the medical admission unit before any handover was received, and a further two patients arrived without any handover at all. A quality improvement project was therefore conducted using a 'Plan, Do, Study, Act' cycle model for improvement to address this issue. P - Plan: as there was no framework to support doctors with handover, a series of standard handover procedures were designed. D - Do: the procedures were disseminated to all staff, and championed by key stakeholders, including the clinical director and matron of the medical admission unit. S - STUDY: Measurements were repeated 3 months later and showed no change in the primary end points. A - ACT: The post take ward round sheet was redesigned, creating a checkbox for a medical admission unit doctor to document that handover had occurred. Nursing staff were prohibited from moving the patient off the ward until this had been completed. This later evolved into a separate handover sheet. Six months later, a repeat study revealed that only one patient each week was arriving before or without a verbal handover. Using a 'Plan, Do, Study, Act' business improvement tool helped to improve patient care.
Essack, Zaynab; Toohey, Jacintha; Strode, Ann
2016-05-01
In South Africa children under the age of 18 are legal minors and considered not fully capable of acting independently. However, in certain defined circumstances the law has granted minors the capacity to act independently, including regarding their sexual and reproductive health (SRH). This study explored the perspectives and practices of 17 social workers from KwaZulu-Natal on legislation relevant to adolescents' evolving sexual and reproductive health and rights and the decriminalisation of consensual underage sex. A key finding was that many social workers have conservative views about adolescent access to SRH advice and services and many were critical of the recent decriminalisation of underage consensual sex. In the main, social workers were concerned that adolescents lack the capacity to make SRH care decisions and that liberal laws promote underage sex rather than protect adolescents. Despite antagonistic views of SRH laws related to adolescents, many social workers felt that they are able to uphold their professional rather than personal views in their work. These findings are important given that a key barrier to adolescent access and uptake of SRH advice and services relates to concerns that they will be judged. Therefore service providers need to be regularly updated on adolescent SRH issues (including rights, laws, and policies) and be engaged in critical thinking about conflicting cultural, moral and personal judgements around adolescent sexuality. Such training should include counselling and communication skills that address issues on confidentiality, adolescents' dignity, privacy and best interests. Copyright © 2016 Elsevier Inc. All rights reserved.
How Well Does the World Health Organization Definition of Domestic Violence Work for India?
Kalokhe, Ameeta S.; Potdar, Ratnaprabha R.; Stephenson, Rob; Dunkle, Kristin L.; Paranjape, Anuradha; del Rio, Carlos; Sahay, Seema
2015-01-01
Domestic violence (DV) is reported by 40% of married women in India and associated with substantial morbidity. An operational research definition is therefore needed to enhance understanding of DV epidemiology in India and inform DV interventions and measures. To arrive at a culturally-tailored definition, we aimed to better understand how definitions provided by the World Health Organization and the 2005 India Protection of Women from Domestic Violence Act match the perceptions of behaviors constituting DV among the Indian community. Between September 2012 and January 2013, 16 key informant interviews with experts in DV and family counseling and 2 gender-concordant focus groups of lay community members were conducted in Pune, India to understand community perceptions of the definition of DV, perpetrators of DV, and examples of DV encountered by married women in Pune, India. Several key themes emerged regarding behaviors and acts constituting DV including 1) the exertion of control over a woman’s reproductive decision-making, mobility, socializing with family and friends, finances, and access to food and nutrition, 2) the widespread acceptance of sexual abuse and the influences of affluence on sexual DV manifestations, 3) the shaping of physical abuse experiences by readily-available tools and the presence of witnesses, 4) psychological abuse for infertility, dowry, and girl-children, and 5) the perpetration of DV by the husband and other members of his family. Findings support the need for a culturally-tailored operational definition that expands on the WHO surveillance definition to inform the development of more effective DV intervention strategies and measures. PMID:25811374
How well does the World Health Organization definition of domestic violence work for India?
Kalokhe, Ameeta S; Potdar, Ratnaprabha R; Stephenson, Rob; Dunkle, Kristin L; Paranjape, Anuradha; Del Rio, Carlos; Sahay, Seema
2015-01-01
Domestic violence (DV) is reported by 40% of married women in India and associated with substantial morbidity. An operational research definition is therefore needed to enhance understanding of DV epidemiology in India and inform DV interventions and measures. To arrive at a culturally-tailored definition, we aimed to better understand how definitions provided by the World Health Organization and the 2005 India Protection of Women from Domestic Violence Act match the perceptions of behaviors constituting DV among the Indian community. Between September 2012 and January 2013, 16 key informant interviews with experts in DV and family counseling and 2 gender-concordant focus groups of lay community members were conducted in Pune, India to understand community perceptions of the definition of DV, perpetrators of DV, and examples of DV encountered by married women in Pune, India. Several key themes emerged regarding behaviors and acts constituting DV including 1) the exertion of control over a woman's reproductive decision-making, mobility, socializing with family and friends, finances, and access to food and nutrition, 2) the widespread acceptance of sexual abuse and the influences of affluence on sexual DV manifestations, 3) the shaping of physical abuse experiences by readily-available tools and the presence of witnesses, 4) psychological abuse for infertility, dowry, and girl-children, and 5) the perpetration of DV by the husband and other members of his family. Findings support the need for a culturally-tailored operational definition that expands on the WHO surveillance definition to inform the development of more effective DV intervention strategies and measures.
29 CFR 1926.1 - Purpose and scope.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Contract Work Hours and Safety Standards Act. The standards are published in subpart C of this part and... section 107 of the Contract Work Hours and Safety Standards Act having general applicability. ...
48 CFR 222.302 - Liquidated damages and overtime pay.
Code of Federal Regulations, 2010 CFR
2010-10-01
... ACQUISITIONS Contract Work Hours and Safety Standards Act 222.302 Liquidated damages and overtime pay. Upon receipt of notification of Contract Work Hours and Safety Standards Act violations, the contracting...
29 CFR 1926.1 - Purpose and scope.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Contract Work Hours and Safety Standards Act. The standards are published in subpart C of this part and... section 107 of the Contract Work Hours and Safety Standards Act having general applicability. ...
48 CFR 222.302 - Liquidated damages and overtime pay.
Code of Federal Regulations, 2011 CFR
2011-10-01
... ACQUISITIONS Contract Work Hours and Safety Standards Act 222.302 Liquidated damages and overtime pay. Upon receipt of notification of Contract Work Hours and Safety Standards Act violations, the contracting...
20 CFR 220.10 - Disability for work in an employee's regular railroad occupation.
Code of Federal Regulations, 2010 CFR
2010-04-01
... railroad occupation. 220.10 Section 220.10 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT DETERMINING DISABILITY Disability Under the Railroad Retirement Act for Work in an Employee's Regular Railroad Occupation § 220.10 Disability for work in an employee's regular...
40 CFR 35.907 - Municipal pretreatment program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.907... pretreatment program if the Regional Administrator determines that: (1) The municipal treatment works: (i... Act, or (ii) Expects to serve industries connecting into the works in accordance with section 301(i)(2...
Moll, Sandra E
2014-02-08
There is a high rate of stress and mental illness among healthcare workers, yet many continue to work despite symptoms that affect their performance. Workers with mental health issues are typically ostracized and do not get the support that they need. If issues are not addressed, however, they could become worse and compromise the health and safety, not only of the worker, but his/her colleagues and patients. Early identification and support can improve work outcomes and facilitate recovery, but more information is needed about how to facilitate this process in the context of healthcare work. The purpose of this study was to explore the key individual and organizational forces that shape early intervention and support for healthcare workers who are struggling with mental health issues, and to identify barriers and opportunities for change. A qualitative, case study in a large, urban healthcare organization was conducted in order to explore the perceptions and experiences of employees across the organization. In-depth interviews were conducted with eight healthcare workers who had experienced mental health issues at work as well as eight workplace stakeholders who interacted with workers who were struggling (managers, coworkers, union leaders). An online survey was completed by an additional 67 employees. Analysis of the interviews and surveys was guided by a process of interpretive description to identify key barriers to early intervention and support. There were many reports of silence and inaction in response to employee mental health issues. Uncertainty in identifying mental health problems, stigma regarding mental ill health, a discourse of professional competence, social tensions, workload pressures, confidentiality expectations and lack of timely access to mental health supports were key forces in preventing employees from getting the help that they needed. Although there were a few exceptions, the overall study findings point to many barriers to supporting employees with mental health issues. In order to address the complex knowledge, attitudinal, interpersonal and organizational barriers to action, a multi-layered knowledge translation strategy is needed, that considers not only mental health literacy and anti-stigma interventions, but addresses the unique context of the work environment that can act as a barrier to change.
2014-01-01
Background There is a high rate of stress and mental illness among healthcare workers, yet many continue to work despite symptoms that affect their performance. Workers with mental health issues are typically ostracized and do not get the support that they need. If issues are not addressed, however, they could become worse and compromise the health and safety, not only of the worker, but his/her colleagues and patients. Early identification and support can improve work outcomes and facilitate recovery, but more information is needed about how to facilitate this process in the context of healthcare work. The purpose of this study was to explore the key individual and organizational forces that shape early intervention and support for healthcare workers who are struggling with mental health issues, and to identify barriers and opportunities for change. Methods A qualitative, case study in a large, urban healthcare organization was conducted in order to explore the perceptions and experiences of employees across the organization. In-depth interviews were conducted with eight healthcare workers who had experienced mental health issues at work as well as eight workplace stakeholders who interacted with workers who were struggling (managers, coworkers, union leaders). An online survey was completed by an additional 67 employees. Analysis of the interviews and surveys was guided by a process of interpretive description to identify key barriers to early intervention and support. Results There were many reports of silence and inaction in response to employee mental health issues. Uncertainty in identifying mental health problems, stigma regarding mental ill health, a discourse of professional competence, social tensions, workload pressures, confidentiality expectations and lack of timely access to mental health supports were key forces in preventing employees from getting the help that they needed. Although there were a few exceptions, the overall study findings point to many barriers to supporting employees with mental health issues. Conclusions In order to address the complex knowledge, attitudinal, interpersonal and organizational barriers to action, a multi-layered knowledge translation strategy is needed, that considers not only mental health literacy and anti-stigma interventions, but addresses the unique context of the work environment that can act as a barrier to change. PMID:24507543
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC.
The copyright law of the United States is amended in its entirety by this act that takes effect in 1978. Literary works; musical works; dramatic works; pantomimes and choreographic works; pictorial, graphic, and sculptural works; motion pictures and other audiovisual works; and sound recordings are included in the subject matter of copyright.…
29 CFR 5.17 - Withdrawal of approval of a training program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... CONTRACTS SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts... for the classification of work actually performed until an acceptable program is approved. ...
29 CFR 6.21 - Ineligible list.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... name of any respondent found to be in aggravated or willful violation of the Contract Work Hours and...
29 CFR 6.21 - Ineligible list.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Service Contract Act (and Under the Contract Work Hours and Safety Standards Act for Contracts Subject to... name of any respondent found to be in aggravated or willful violation of the Contract Work Hours and...
1975-12-01
In Block 20, If different from Report) IS. SUPPLEMENTARY NOTES 19. KEY WORDS (Continu, on reverse aide If necesary and Identify by block number) 20...AST’R ACT (Cndbie m reverse ohb N n..e~ww and ideti fy by block number) DD JA 473 EDITION OF I NOV GS 15 OBSOLETE 4~ -i ~SECURITY CLASSIFICATION OF...and Harbor Act of 1867 provided Federal assistance for improving the harbor and channel. Revetments and channel piers were constructed under this Act
Mental capacity and decision making: defining capacity.
Dimond, Bridgit
The Mental Capacity Act 2005 came fully into force on 1st October 2007 (some sections came into force on 1 April 2007). This series of articles considers some of the key features of the Act, including the concepts of best interests, the lasting power of attorney, the role of the new Court of Protection, the Office of Public Guardian and the deputies of the Court, to name but a few. This first article looks at the central feature of the Act: how mental capacity is determined.
Rubio-Aurioles, Eusebio; El-Meliegy, Amr; Abdulwahed, Samer; Henneges, Carsten; Sorsaburu, Sebastian; Gurbuz, Sirel
2015-02-01
Phosphodiesterase type 5 (PDE5) inhibitors have discontinuation rates as high as 60% in men with erectile dysfunction. Treatment satisfaction has been significantly associated with treatment continuation. Understanding key characteristics in terms of treatment preference, relationship, and lifestyle issues could provide direction on how to improve compliance with PDE5 inhibitor treatment globally. The objective was to identify subgroups of interest in the pooled database of two observational studies conducted in Latin America (LA) and Middle East/North Africa (MENA) exploring patient characteristics and prescription of either a long- or short-acting PDE5 inhibitor at baseline. Two identical prospective, non-interventional, observational, studies in MENA (N = 493) and LA (N = 511) treated men with an 'on demand' (pro re nata, PRN) PDE5 inhibitor (sildenafil, tadalafil, vardenafil, or lodenafil) during 6 months. In this post-hoc meta-analysis of two observational studies with equal design, pooled data were analyzed to determine patient characteristics and PDE5 inhibitor prescribed/used most likely to be associated with patient expectations, satisfaction, self-esteem, and patient-partner relationships. Decision tree analyses, with and without weighting, were used to identify and describe key features. In each analysis of patient expectations, patient-partner relationship, and self-esteem, we describe the two major subgroups at baseline for each decision tree. Analyses of patient expectations and sexual self-esteem revealed that patients prescribed long-acting PDE5 inhibitors (59%) highlighted the importance of treatment effect duration, second to partner satisfaction with treatment, while patients prescribed short-acting PDE5 inhibitors (32%) placed less importance on treatment effect duration but considerable importance on treatment effect lasting until intercourse completion. Further insights regarding patients, partner relationship characteristics, and treatment expectations were identified. Our analyses have described key characteristics, such as self- and partner perceptions, sexual attitudes, and treatment expectations in relation to the patients' country and prescribed treatment, which might guide treatment decisions in MENA and LA men with ED.
Best interests of adults who lack capacity part 2: key considerations.
Griffith, Richard
Last month's article discussed the key concepts underpinning the notion of best interests. In this article the author discusses the requirements for determining the best interests of an adult who lacks capacity under the provisions of the Mental Capacity Act 2005 and its code of practice (Department for Constitutional Affairs 2007).
Public Expenditures on Children through 2008: Key Facts
ERIC Educational Resources Information Center
Macomber, Jennifer; Isaacs, Julia; Kent, Adam; Vericker, Tracy
2010-01-01
This report provides the key findings on the public spending on children through 2008. They are: (1) Spending on children increased under the American Recovery and Reinvestment Act (ARRA) and other stimulus spending, but not proportionately to other federal spending. As ARRA expires, we project that spending on children will decline, assuming no…
New Leeway on Horizon under NCLB
ERIC Educational Resources Information Center
McNeil, Michele
2011-01-01
As the clock ticks toward President Barack Obama's back-to-school deadline for rewriting the No Child Left Behind Act, U.S. Secretary of Education Arne Duncan is preparing to grant states relief from key provisions of the federal school accountability law in exchange for what he calls "commitments to key reforms." The move comes as…
Executive Leadership Concepts for Higher Education.
ERIC Educational Resources Information Center
Satterlee, Brian
Several key concepts shed light on the traits and processes of leadership in educational settings. First, the term leadership can be understood as the act of persuading others to set aside individual concerns and pursue a common goal, with communication representing a key ability of leaders. The Communication Model provides a useful, open systems…
Code of Federal Regulations, 2013 CFR
2013-04-01
... to the One-Stop system and Workforce Investment Act (WIA) programs? 645.430 Section 645.430 Employees... GRANTS State Formula Grants Administration § 645.430 How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act (WIA) programs? (a) As provided in the Workforce...
Code of Federal Regulations, 2014 CFR
2014-04-01
... to the One-Stop system and Workforce Investment Act (WIA) programs? 645.430 Section 645.430 Employees... GRANTS State Formula Grants Administration § 645.430 How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act (WIA) programs? (a) As provided in the Workforce...
Code of Federal Regulations, 2012 CFR
2012-04-01
... to the One-Stop system and Workforce Investment Act (WIA) programs? 645.430 Section 645.430 Employees... GRANTS State Formula Grants Administration § 645.430 How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act (WIA) programs? (a) As provided in the Workforce...
Code of Federal Regulations, 2010 CFR
2010-04-01
... to the One-Stop system and Workforce Investment Act (WIA) programs? 645.430 Section 645.430 Employees... GRANTS State Formula Grants Administration § 645.430 How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act (WIA) programs? (a) As provided in the Workforce...
Code of Federal Regulations, 2011 CFR
2011-04-01
... to the One-Stop system and Workforce Investment Act (WIA) programs? 645.430 Section 645.430 Employees... GRANTS State Formula Grants Administration § 645.430 How does the Welfare-to-Work program relate to the One-Stop system and Workforce Investment Act (WIA) programs? (a) As provided in the Workforce...
ERIC Educational Resources Information Center
Freeman, Melissa
2010-01-01
Positioning theory provides a lens through which to view the narrative accounts of working-class parents as dynamic, intentional acts of positioning intended to gain the recognition of school personnel as full partners in the education of their children. Knowing that school personnel will not treat them with the kind of respect given middle-class…
Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats
USDA-ARS?s Scientific Manuscript database
Long-acting glucagon-like peptide-1 receptor (GLP-1R) agonists have both glucose- and weight-lowering effects. The brain is poised to mediate both of these actions since GLP-1Rs are present in key areas known to control weight and glucose. Although some research has been performed on the effects of ...
State Capacity to Link K-12/Postsecondary Data Systems and Report Key Indicators
ERIC Educational Resources Information Center
Data Quality Campaign, 2016
2016-01-01
The Every Student Succeeds Act (ESSA) provides an opportunity to produce high quality postsecondary indicators and, as available, publicly report them in ways that inform, engage, and empower communities. As first "required" in 2009's American Recovery and Reinvestment Act (ARRA) stimulus law, almost every state has linked its K-12 and…
ERIC Educational Resources Information Center
Sagar, Sam S.; Jowett, Sophia
2012-01-01
Athletes' perceptions of coaches' communicative acts of interaction in two key interpersonal situations were examined, and their impact on the athletes: (a) when athletes lose competitions; and, (b) when athletes make mistakes in training. Athletes (N = 324, M age = 20.11) completed an open-ended survey. Data were deductively and inductively…
ERIC Educational Resources Information Center
Arnold, Jean B.
1993-01-01
The Family and Medical Leave Act (FMLA) gives employees the right to take up to 12 weeks of unpaid leave a year for medical or family reasons. Provides key provisions of FMLA as they apply to schools and advises districts to consult school attorneys to help ensure compliance with the act and with the interim regulations issued last summer. (MLF)
How Illinois' College and Career Readiness (CCR) Pilot Sites Address Five Key Goals. In Brief
ERIC Educational Resources Information Center
Castro, Erin L.; Bragg, Debra D.; Khan, Sadya; Baber, Lorenzo D.; Common, Brandon H.
2010-01-01
In 2007, the Illinois General Assembly passed Public Act 0950694, "The College and Career Readiness Pilot Act", in an effort to reduce remediation within Illinois' community colleges. An important objective of this legislation was to better prepare students to be successful in transitioning from high school to college. According to the…
ERIC Educational Resources Information Center
Office of Postsecondary Education, US Department of Education, 2013
2013-01-01
This ninth report on teacher quality presents information states reported to the U.S. Department of Education (Department) in October 2011. Title II of the "Higher Education Act of 1965" (HEA), as amended in 2008 by the "Higher Education Opportunity Act" (HEOA), requires states to report annually on key elements of their…
25 CFR 162.101 - What key terms do I need to know?
Code of Federal Regulations, 2010 CFR
2010-04-01
... Agricultural Resources Management Act of December 3, 1993 (107 Stat. 2011, 25 U.S.C. 3701 et seq.), as amended... tribe acting on behalf of BIA under § 162.109 of this part. Bond means security for the performance of... uncertain in duration, including a life estate. Lease means a written agreement between Indian landowners...
Marketing, Parental Choice and Strategic Planning: An Opportunity or Dilemma for UK Schools?
ERIC Educational Resources Information Center
Giles, Corrie
Site-based management, parental choice, and accountability for the efficient, effective, and economic use of public resources in England and Wales were key themes of the 1988 Education Reform Act. The 1993 Education Act opened the way for greater choice in the marketplace by encouraging specialization and/or selection by aptitude/ability in…
NASA Technical Reports Server (NTRS)
Schertler, R. J.
1986-01-01
An overview of the ACTS Experiments Program is presented. ACTS is being developed and will flight test the advanced technologies associated with: a Ka-band multibeam antenna, onboard signal processing and switching as well as laser communications. A nominal 3 yr experiments program is planned. Through the experiments program, the capabilities of the ACTS system will be made available to U.S. industry, university and government experimenters to test, prove the feasibility and evaluate the key ACTS system technologies. Communication modes of operation using the baseband processor and microwave switch matrix are presented, along with the antenna coverage pattern. Potential experiment categories are also presented and briefly discussed. An overall schedule of activities associated with the experiments program is outlined. Results of the ACTS Experiments Program will provide information vital to successful industry implementation of ACTS technology in a future operational system.
Status of the Landsat Data Continuity Mission
NASA Technical Reports Server (NTRS)
Irons, James R.; Ochs, William R.
2004-01-01
Efforts to begin implementing a successor mission to Landsat 7, called the Landsat Data Continuity Mission (LDCM), suffered a set back in 2003. NASA and the Department of Interior (DOI)/U.S. Geological Survey (USGS) currently manage the Landsat Program as an interagency partnership. The two agencies had planned to purchase data meeting LDCM specifications from a privately owned and commercially operated satellite system beginning in March, 2007. This approach represented a departure from the traditional procurement of a government owned and operated satellite system. NASA, however, cancelled a Request-for-Proposals (RFP) for providing the required data after an evaluation of proposals received from private industry. NASA concluded that the proposals failed to meet a key objective and expectation of the RFP, namely, to form a fair and equitable partnership between the Government and private industry. Alternative strategies for implementing an LDCM are now under consideration. The Executive Office of the President formed an interagency working group on the LDCM following the RFP cancellation. The working group is considering other options for implementing a successor system to Landsat 7 consistent with the Land Remote Sensing Policy Act of 1992 (Public Law 102-555). This Act lists four management options for consideration: 1) private sector funding and management; 2) an international consortium; 3) funding and management by the U.S. Government; and 4) a cooperative effort between the US. Government and the private sector. The working group is currently attempting to minimize the risk of a Landsat data gap through development of a strategy that leads to a Landsat 7 successor mission. The selected strategy and the status of the mission will be presented at the Symposium.
Final Report of the Advanced Coal Technology Work Group
The Advanced Coal Technology workgroup reported to the Clean Air Act Advisory Committee. This page includes the final report of the Advanced Coal Technology Work Group to the Clean Air Act Advisory Committee.
The Assisted Decision-Making (Capacity) Act 2015: what it is and why it matters.
Kelly, B D
2017-05-01
Ireland's Assisted Decision-Making (Capacity) Act 2015 was signed by President Higgins in December 2015 and scheduled for commencement in 2016. To explore the content and implications of the 2015 Act. Review of the 2015 Act and related literature. The 2015 Act places the "will and preferences" of persons with impaired mental capacity at the heart of decision-making relating to "personal welfare" (including healthcare) and "property and affairs". Capacity is to be "construed functionally" and interventions must be "for the benefit of the relevant person". The Act outlines three levels of decision-making assistance: "decision-making assistant", "co-decision-maker" (joint decision-maker) and "decision-making representative" (substitute decision-maker). There are procedures relating to "enduring power of attorney" and "advance healthcare directives"; in the case of the latter, a "refusal of treatment" can be legally binding, while a "request for a specific treatment" must "be taken into consideration". The 2015 Act is considerably more workable than the 2013 Bill that preceded it. Key challenges include the subtle decision-making required by patients, healthcare staff, Circuit Court judges and the director of the Decision Support Service; implementation of "advance healthcare directives", especially if they do not form part of a broader model of advance care planning (incorporating the flexibility required for unpredictable future circumstances); and the over-arching issue of logistics, as very many healthcare decisions are currently made in situations where the patient's capacity is impaired. A key challenge will lie in balancing the emphasis on autonomy with principles of beneficence, mutuality and care.
75 FR 51840 - State of Arizona Resource Advisory Council Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-23
... Policy and Management Act of 1976 and the Federal Advisory Committee Act of 1972, the U.S. Department of... implemented; RAC questions on BLM District Managers' Reports; and reports by RAC working groups. A public...) Working Group Report, REA Working Group meeting schedule and future BLM/FS recreation fee proposals. The...
45 CFR 2543.84 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2013 CFR
2013-10-01
... contracts and in excess of $2500 for other contracts that involve the employment of mechanics or laborers... Section 102 of the Act, each contractor shall be required to compute the wages of every mechanic and... to construction work and provides that no laborer or mechanic shall be required to work in...
45 CFR 2543.84 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2011 CFR
2011-10-01
... contracts and in excess of $2500 for other contracts that involve the employment of mechanics or laborers... Section 102 of the Act, each contractor shall be required to compute the wages of every mechanic and... to construction work and provides that no laborer or mechanic shall be required to work in...
45 CFR 2543.84 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2012 CFR
2012-10-01
... contracts and in excess of $2500 for other contracts that involve the employment of mechanics or laborers... Section 102 of the Act, each contractor shall be required to compute the wages of every mechanic and... to construction work and provides that no laborer or mechanic shall be required to work in...
45 CFR 2543.84 - Contract Work Hours and Safety Standards Act.
Code of Federal Regulations, 2014 CFR
2014-10-01
... contracts and in excess of $2500 for other contracts that involve the employment of mechanics or laborers... Section 102 of the Act, each contractor shall be required to compute the wages of every mechanic and... to construction work and provides that no laborer or mechanic shall be required to work in...
Reflections on civil society and gender.
Thacker, P
1997-07-01
This article discusses ways to empower women in rural Nepal. Nepal needs to plan for the expected doubling of its population in the next 28 years. It is important that priorities be established in national development strategies. Nongovernmental organizations (NGOs) and the private sector will also play a role in development. Nepal is a multiethnic society with about 42% of its population living in poverty. About 42% are aged under 15 years. A major task of development is to engender a sense of hopefulness for young people, despite a deteriorating social situation. The government, the private sector, and NGOs must all act in a socially responsible manner by creating job opportunities and building infrastructure. Development should not concentrate on projects alone and should contribute to an equitable and just society, distributive justice, and sustainability. Economic growth is a lesser concern. Activism and intuition are necessary subjective approaches outside the realm of objective academic research. It is important to retain women's knowledge base of indigenous ways of doing things. Women are participating in NGOs in a variety of capacities. Although women's NGO participation may build important bridges of cooperation, their work remains invisible. NGOs are key players in exposing poor people's agenda in international forums. NGOs work with different ideologies and without political bases, which must be surmounted in building cooperation with the private sector. Elites must act responsibly to expose patriarchy and gender insubordination. Development interventions must be based on gender, economic, and social class relations.
Patel, Harilal; Patel, Prakash; Modi, Nirav; Patel, Pinakin; Wagh, Yogesh; George, Alex; Desai, Nirmal; Srinivas, Nuggehally R
2018-05-08
Development of prodrug of 9-hydroxyrisperidone (paliperidone) long-acting intramuscular injection has enabled delivery over four-week time period with improved compliance. The key aim of this work was to establish a reliable preclinical model which may potentially serve as a screening tool for judging the pharmacokinetics of paliperidone formulation(s) prior to human clinical work. Sparse sampling composite study was used in rats, (Wistar/Sprague-Dawley (SD; n = 10)) and a serial blood sampling study design was used in rabbits (n = 4). Animals received intramuscular injection of paliperidone palmitate in the thigh muscle at dose of 16 (rats) and 4.5 mg/kg (rabbits). Samples were drawn in rats (retro-orbital sinus) and rabbits (central ear artery) and were analysed for paliperidone using liquid chromatography-mass spectrometry/ mass spectrometry (LC-MS/MS) assay. The plasma data was subjected to pharmacokinetic analysis. Following intramuscular injection of depot formulation in Wistar/SD rats and rabbits, absorption of paliperidone was slow and gradual with median value of time to reach maximum concentration (T max ) occurring on day 7. The exposures (i.e. area under the curve (AUC; 0-28) days) were 18,597, 21,865 and 18,120 ng.h/mL, in Wistar, SD and rabbits, respectively. The clearance was slow and supported long half-life (8-10 days). Either one of the two models can serve as a research tool for establishing pharmacokinetics of paliperidone formulation(s).
Preparing displaced adults for the optics/photonics workforce
NASA Astrophysics Data System (ADS)
Hull, Darrell M.
2000-06-01
As the optics/photonics industry continues to grow, the demand for workers is assumed to increase proportionally. Empirical data seem to support this assumption. This increase presents a challenge to optics/photonics education, since they control and assume responsibility for a key factor in the ability of industry to further expand. At the same time, the U.S. government through the Department of Labor and the Workforce Investment Act has requested that communities enact programs for displaced adults to transition to the workplace. A program of study is provided that would assist adults in making this transition from unemployment to the optics/photonics industry, with the necessary general work skills, occupational optics/photonics skills, and ability to progress on the job with academic foundations in math and science.
NASA Astrophysics Data System (ADS)
Alligné, S.; Decaix, J.; Müller, A.; Nicolet, C.; Avellan, F.; Münch, C.
2017-04-01
Due to the massive penetration of alternative renewable energies, hydropower is a key energy conversion technology for stabilizing the electrical power network by using hydraulic machines at off design operating conditions. At full load, the axisymmetric cavitation vortex rope developing in Francis turbines acts as an internal source of energy, leading to an instability commonly referred to as self-excited surge. 1-D models are developed to predict this phenomenon and to define the range of safe operating points for a hydropower plant. These models require a calibration of several parameters. The present work aims at identifying these parameters by using CFD results as objective functions for an optimization process. A 2-D Venturi and 3-D Francis turbine are considered.
Liu, Bin; Tan, Dongsheng; Wang, Xianfu; Chen, Di; Shen, Guozhen
2013-06-10
Flexible and highly efficient energy storage units act as one of the key components in portable electronics. In this work, by planar-integrated assembly of hierarchical ZnCo₂O₄ nanowire arrays/carbon fibers electrodes, a new class of flexible all-solid-state planar-integrated fiber supercapacitors are designed and produced via a low-cost and facile method. The as-fabricated flexible devices exhibit high-efficiency, enhanced capacity, long cycle life, and excellent electrical stability. An enhanced distributed-capacitance effect is experimentally observed for the device. This strategy enables highly flexible new structured supercapacitors with maximum functionality and minimized size, thus making it possible to be readily applied in flexible/portable photoelectronic devices. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Occupational therapy and the Americans with Disabilities Act (ADA).
2000-01-01
Occupational therapy practitioners play a key role in educating the public, as well as persons with disabilities, about their rights and responsibilities under the ADA. Occupational therapy practitioners' understanding of work and task analysis, knowledge of the functional limitations of disability, and experience with reasonable accommodations, adaptive equipment, and environmental adaptations place them in a unique position to serve as a resource in ADA-related matters [EEOC, Title I Technical Assistance Manual sections 3.6, 3.10(6), 4.5(4), 6.2, 6.4, 6.6 (1992)]. The AOTA supports the fundamental purposes of the ADA and encourages its members to assist the public in complying with ADA mandates to promote the inclusion of persons with disabilities into the mainstream of society and the pursuit of meaningful occupations.
Gilmore, Kelly; Hoopes, Andrea J; Cady, Janet; Amies Oelschlager, Anne-Marie; Prager, Sarah; Vander Stoep, Ann
2015-06-01
The purpose of this study was to describe the implementation of a program that provides long-acting reversible contraception (LARC) services within school-based health centers (SBHCs) and to identify barriers and facilitators to implementation as reported by SBHC clinicians and administrators, public health officials, and community partners. We conducted 14 semistructured interviews with key informants involved in the implementation of LARC services. Key informants included SBHC clinicians and administrators, public health officials, and community partners. We used a content analysis approach to analyze interview transcripts for themes. We explored barriers to and facilitators of LARC service delivery across and within key informant groups. The most cited barriers across key informant groups were as follows: perceived lack of provider procedural skills and bias and negative attitudes about LARC methods. The most common facilitators identified across groups were as follows: clear communication strategies, contraceptive counseling practice changes, provider trainings, and stakeholder engagement. Two additional barriers emerged in specific key informant groups. Technical and logistical barriers to LARC service delivery were cited heavily by SBHC administrative staff, community partners, and public health officials. Expense and billing was a major barrier to SBHC administrative staff. LARC counseling and procedural services can be implemented in an SBHC setting to promote access to effective contraceptive options for adolescent women. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Golovatskaya, Eugenia; Dyukarev, Egor
2010-05-01
Role of peatlands in the global greenhouse gases budget is highly relevant. According to present estimates peatlands in undisturbed conditions act as a sink for the atmospheric carbon. Anthropogenic impact on peatlands (melioration, changes in land use, influence of underground water catchments) results in water table lowering, changing in vegetation cover, and degradation of peat deposit. Peatlands could provide a significant positive feedback for climate changes if warming and peatlands drying stimulates bulk soil organic matter decomposition which enhances CO2 release to the atmosphere. Western Siberian peatlands usually represented big bog massifs. Big peatlands have higher stability to external influence. Small peatlands have all signs of big bogs but react on changes in environmental variables more quickly. The present study is devoted to investigation of primary carbon fluxes (CO2 emission and net primary productivity) and carbon balance at oligotrophic bogs in native condition (key area "Bakchar") and under anthropogenic impact (key area "Ob'-Tom'"). The key area "Bakchar" is located between the Iksa and Bakchar rivers (56o58`N 82o36`E) at the Bakcharskoe bog (area 1400 km2). The key area "Ob'-Tom'"is located in the northern part of Ob' and Tom' interfluve (56o21`N 82o31`E). The "Bakchar" key area includes the following ecosystems: pine- shrub-sphagnum community, a similar community with stunted (low) pine trees, and sedge-sphagnum fen. Two small peatlands were studied at Ob' and Tom' interfluve. Kirsanovskoe bog includes pine- shrub-sphagnum community and sedge fen. Timiryazevskoe bog was represented by pine- shrub-sphagnum (TPSS) community and sedge fen. An infrared gas analyzer OPTOGAS 500.4 (OPTEC Corp., St.-Petersburg, Russia) attached to a static opaque plastic been used for carbon dioxide emission measurements. The net primary productivity was measured by clipping method (Golovatskaya and Dyukarev, Plant Soil 2009). Peatlands at "Ob'-Tom'" key area are under impact of water catchments for Tomsk city supply. Changes in deep waters results in changes of hydrological regime and environment transformations. Water level drawdown leads to increase of aerobic layer thickness, intensification of plant remains decomposition, peat layers compacting and rises of CO2 emission from the surface. Carbon dioxide emission from bogs of "Ob'-Tom'" key area is about two times higher than emission from pristine bogs ("Bakchar" key area). Aboveground net primary productivity determined without tree layer at all studied peatlands has similar values. Belowground net primary productivity at "Ob'-Tom'" key area if 4-7 times higher than at "Bakchar" key area depending on the ecosystem type. An essential increase in root density after water level depletion results in increase on total net productivity by 2.4 times. Carbon budget for pristine peatlands ("Bakchar" key area) varies from 27 (open fen) to 46 (low ryam) gC/m2/yr. Peatlands of "Ob'-Tom'" key area accumulates about 210 gC/m2/yr in average. Our observations of the elements of carbon exchange have shown that at present all studied peatlands act as carbon sinks. Long-term water table lowering at least at first stage stipulates carbon removing from the atmosphere and accumulation in a form of peat. Work was partially supported by Russian Fund of Basic Researches (08-05-00426/a, 08-05-92501).
Hall, David S; Lockwood, David J; Poirier, Shawn; Bock, Christina; MacDougall, Barry R
2012-06-28
The present work utilizes Raman and infrared (IR) spectroscopy, supported by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) to re-examine the fine structural details of Ni(OH)(2), which is a key material in many energy-related applications. This work also unifies the large body of literature on the topic. Samples were prepared by the galvanostatic basification of nickel salts and by aging the deposits in hot KOH solutions. A simplified model is presented consisting of two fundamental phases (α and β) of Ni(OH)(2) and a range of possible structural disorder arising from factors such as impurities, hydration, and crystal defects. For the first time, all of the lattice modes of β-Ni(OH)(2) have been identified and assigned using factor group analysis. Ni(OH)(2) films can be rapidly identified in pure and mixed samples using Raman or IR spectroscopy by measuring their strong O-H stretching modes, which act as fingerprints. Thus, this work establishes methods to measure the phase, or phases, and disorder at a Ni(OH)(2) sample surface and to correlate desired chemical properties to their structural origins.
Compensation for occupational injuries and diseases in special populations: farmers and soldiers.
Kwon, Young-Jun; Lee, Soo-Jin
2014-06-01
Some types of workers such as farmers and soldiers are at a higher risk of work-related injury and illness than workers from other occupations. Despite this fact, they are not covered under the Industrial Safety Health (ISH) Act or the Industrial Accident Compensation Insurance (IACI) Act. The Safety Aid System for Farmers (SASF) is a voluntary insurance scheme, and it is the only public compensation plan for self-employed farmers. Fifty percent of SASF premiums are subsidized by the Korean government. Soldiers are compensated by the Veterans' Pension (VP) Act. The approval standard of and procedure for the VP Act are provided in the Decree of VP Act, and the Council for VP Benefits determines work-relatedness in the claimed cases. Meanwhile, SASF applies the insurance clause automatically without any expert advice or additional procedures. Furthermore, compared with IACI, these programs pay fewer benefits to workers. Thus, a stronger institutional strategy is needed to maintain a safe work environment, to protect workers' health in unavoidably hazardous environments, and to compensate for work-related injuries and diseases.
The Human Rights Act: What are the implications for older people?
2001-06-01
Help the Aged is launching a report outlining the terms of the Human Rights Act and its implications both for older people themselves and for public bodies responsible for providing services to them. Tessa Harding, head of policy at Help the Aged said: 'The Human Rights Act is an important turning point for older people. Not only does it establish key rights of individuals to freedom from inhuman and degrading treatment, to private and family life and so on; it also prohibits discrimination in accessing these rights.We expect older people and their advocates to use the Act to ensure greater fairness and equality in our society.'
Teaching Behavioral Ethics: Overcoming the Key Impediments to Ethical Behavior
ERIC Educational Resources Information Center
Schwartz, Mark S.
2017-01-01
To better understand the ethical decision-making process and why individuals fail to act ethically, the aim of this article is to explore what are seen as the key impediments to ethical behavior and their pedagogical implications. Using the ethical decision-making process proposed by Rest as an overarching framework, the article examines the…
The maintenance of key biodiversity attributes through ecosystem restoration operations
Robert W. Gray; Bruce A. Blackwell
2008-01-01
The requirement to manage for key biodiversity attributes in dry forest ecosystems is mandated in the Forest Practices Code Act of British Columbia. These attributes include snags, large old trees, and large organic debris. In the Squamish Forest District dry forest restoration activities center on the use of thinning operations followed by prescribed fire to restore...
Academic Technology Transfer: Tracking, Measuring and Enhancing Its Impact
ERIC Educational Resources Information Center
Fraser, John
2010-01-01
Since the 1980 passage of the US Bayh-Dole Act, academic technology transfer has gained profile globally as a key component of knowledge-driven economic development. Research universities are seen as key contributors. In this article, focusing on the USA and drawing on over twenty years of experience in the field of academic technology transfer in…
When Nice Won't Suffice: Honest Discourse Is Key to Shifting School Culture
ERIC Educational Resources Information Center
MacDonald, Elisa
2011-01-01
The "culture of nice" is the underlying culture that inhibits a team of teachers from reaching a level of rigorous collaborative discourse where teachers are challenging each other's and their own thinking, beliefs, assumptions, and practice. This article discusses how honest discourse can be the key to shifting school culture. The act of…
States' Perspectives on Waivers: Relief from NCLB, Concern about Long-Term Solutions
ERIC Educational Resources Information Center
McMurrer, Jennifer; Yoshioka, Nanami
2013-01-01
On February 9, 2012, U.S. Secretary of Education Arne Duncan granted 10 states waivers of key accountability requirements of the Elementary and Secondary Education Act (ESEA), as amended by the No Child Left Behind (NCLB) Act. One year later, applications for this ESEA flexibility, also known as NCLB waivers, had been approved for an additional 24…
The North-American Long-Term Soil Productivity Study: Concepts and literature
Deborah S. Page-Dumroese
2010-01-01
The resiliency of forest sites after a pulse disturbance is one of the key questions mandated by the National Forest Management Act (NFMA) of 1976. This Act mandated that we maintain the productive capacity of federally managed stands. The original USDA Forest Service soil quality standards were based largely on professional judgment. The North American Long-Term Soil...
ERIC Educational Resources Information Center
Statham, June
This 3-year study examined the implementation of the Children Act in Wales, which deals with providing, coordinating, and regulating day care and related services for children under 8 years. Data were collected through interviews with key officers and representatives of child care organizations, a national survey of day care providers, and an…
ERIC Educational Resources Information Center
Office of Special Education and Rehabilitative Services, US Department of Education, 2010
2010-01-01
The "29th Annual Report to Congress on the Implementation of the Individuals with Disabilities Education Act, 2007" focuses on key state performance data in accordance with recommendations of the President's Commission on Excellence in Special Education. Volume 1 focuses on the children and students being served under "IDEA"…
Promises To Keep: A Decade of Federal Enforcement of the Americans with Disabilities Act, 1990-2000.
ERIC Educational Resources Information Center
National Council on Disability, Washington, DC.
This report is the third in a series of independent analyses by the National Council on Disability on federal enforcement of civil rights laws. This report looks at the Americans with Disabilities Act (ADA) enforcement activities from 1990 to 1999 of four key federal agencies: the Department of Justice, the Equal Employment Opportunity Commission…
A Question of Priorities: A Critical Investigation of the McKinney-Vento Act
ERIC Educational Resources Information Center
Cunningham, Keith Alan
2014-01-01
This critical policy ethnography analyzes the McKinney-Vento Act and how the policy is put into practice at a school district within Central Texas. Data comes from conversations with educators occupying key roles within the McKinney-Vento operational bureaucracy at the school district and the researcher's experience as an educator and volunteer at…
77 FR 76356 - Privacy of Consumer Financial Information Under Title V of the Gramm-Leach-Bliley Act
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-28
... Under Title V of the Gramm-Leach-Bliley Act CFR Correction In Title 17 of the Code of Federal...). (2) Title. (3) Key frame (Why?, What?, How?). (4) Disclosure table (``Reasons we can share your... financial institution provides the model form and that institution is clearly identified in the title on...
Modeling linear and cyclic PKS intermediates through atom replacement.
Shakya, Gaurav; Rivera, Heriberto; Lee, D John; Jaremko, Matt J; La Clair, James J; Fox, Daniel T; Haushalter, Robert W; Schaub, Andrew J; Bruegger, Joel; Barajas, Jesus F; White, Alexander R; Kaur, Parminder; Gwozdziowski, Emily R; Wong, Fiona; Tsai, Shiou-Chuan; Burkart, Michael D
2014-12-03
The mechanistic details of many polyketide synthases (PKSs) remain elusive due to the instability of transient intermediates that are not accessible via conventional methods. Here we report an atom replacement strategy that enables the rapid preparation of polyketone surrogates by selective atom replacement, thereby providing key substrate mimetics for detailed mechanistic evaluations. Polyketone mimetics are positioned on the actinorhodin acyl carrier protein (actACP) to probe the underpinnings of substrate association upon nascent chain elongation and processivity. Protein NMR is used to visualize substrate interaction with the actACP, where a tetraketide substrate is shown not to bind within the protein, while heptaketide and octaketide substrates show strong association between helix II and IV. To examine the later cyclization stages, we extended this strategy to prepare stabilized cyclic intermediates and evaluate their binding by the actACP. Elongated monocyclic mimics show much longer residence time within actACP than shortened analogs. Taken together, these observations suggest ACP-substrate association occurs both before and after ketoreductase action upon the fully elongated polyketone, indicating a key role played by the ACP within PKS timing and processivity. These atom replacement mimetics offer new tools to study protein and substrate interactions and are applicable to a wide variety of PKSs.
Mental Capacity and Mental Health Acts part 1: advance decisions.
Griffith, Richard
The Department of Health is undertaking a review of the Mental Health Act 1983 code of practice and as part of that review has opened a consultation on what changes should be made. One key area for change is a chapter that provides clearer information about the interface between the Mental Health Act 1983 and the Mental Capacity Act 2005. Both the House of Commons Health Select Committee and the House of Lords Mental Capacity Act Committee have argued that poor understanding of the interface has led to flawed decision making by doctors and nurses. In the first of a short series of articles, Richard Griffith considers the interface between these two important statutes, beginning with advance decisions to refuse treatment (ADRT).
75 FR 21035 - Notice of Rescheduled Meetings of the Pinedale Anticline Working Group, Wyoming
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-22
...-LXSI016K0000] Notice of Rescheduled Meetings of the Pinedale Anticline Working Group, Wyoming AGENCY: Bureau of... Land Policy and Management Act (1976) and the Federal Advisory Committee Act (1972), the U.S. Department of the Interior, Bureau of Land Management (BLM) Pinedale Anticline Working Group (PAWG) will meet...
Code of Federal Regulations, 2011 CFR
2011-01-01
... regarding âliquidated damageâ assessments under the Contract Work Hours and Safety Standards Act, and... authority to take action regarding “liquidated damage” assessments under the Contract Work Hours and Safety... nonconstruction contracts as they are subject to the Conract Work Hours and Safety Standards Act, in regards to...
Code of Federal Regulations, 2010 CFR
2010-01-01
... regarding âliquidated damageâ assessments under the Contract Work Hours and Safety Standards Act, and... authority to take action regarding “liquidated damage” assessments under the Contract Work Hours and Safety... nonconstruction contracts as they are subject to the Conract Work Hours and Safety Standards Act, in regards to...
Sex, Money and the Equal Pay Act
ERIC Educational Resources Information Center
Feldman, Edwin B.
1973-01-01
Institutions who justify a wage differential between male and female custodians on the basis that women typically do the lighter work, and men the heavier, can find themselves in trouble. The Equal Pay Act of 1963 requires that men and women get the same pay for equal work -- and all custodial work is substantially equal to the Labor Department.…
Equal Pay Act: Wage Differentials for Time of Day Worked
ERIC Educational Resources Information Center
Stanford, Richard Alan
1974-01-01
The Supreme Court held in Corning Glass Works cases involving male only employees for night shifts that the time of day worked could constitute a factor other than sex whereby the wage differential might qualify as an exception under the Equal Pay Act. Shift differentials could be legal if proven to be nondiscriminatory. (LBH)
ACT Reporting Category Interpretation Guide: Version 1.0. ACT Working Paper 2016 (05)
ERIC Educational Resources Information Center
Powers, Sonya; Li, Dongmei; Suh, Hongwook; Harris, Deborah J.
2016-01-01
ACT reporting categories and ACT Readiness Ranges are new features added to the ACT score reports starting in fall 2016. For each reporting category, the number correct score, the maximum points possible, the percent correct, and the ACT Readiness Range, along with an indicator of whether the reporting category score falls within the Readiness…
ACHP | Advisory Council on Historic Preservation
Search Recovery Act skip specific nav links Home arrow Recovery Act Recovery Act Recovery Act Economics creation, community revitalization, and sustainable development. Click here to read about Economics and information on Indian Country Works. Recovery Act | Economics | Section 106 Q&A | Tool Kit | Recovery
Challenges facing the United States of America in implementing universal coverage.
Rice, Thomas; Unruh, Lynn Y; Rosenau, Pauline; Barnes, Andrew J; Saltman, Richard B; van Ginneken, Ewout
2014-12-01
In 2010, immediately before the United States of America (USA) implemented key features of the Affordable Care Act (ACA), 18% of its residents younger than 65 years lacked health insurance. In the USA, gaps in health coverage and unhealthy lifestyles contribute to outcomes that often compare unfavourably with those observed in other high-income countries. By March 2014, the ACA had substantially changed health coverage in the USA but most of its main features--health insurance exchanges, Medicaid expansion, development of accountable care organizations and further oversight of insurance companies--remain works in progress. The ACA did not introduce the stringent spending controls found in many European health systems. It also explicitly prohibits the creation of institutes--for the assessment of the cost-effectiveness of pharmaceuticals, health services and technologies--comparable to the National Institute for Health and Care Excellence in the United Kingdom of Great Britain and Northern Ireland, the Haute Autorité de Santé in France or the Pharmaceutical Benefits Advisory Committee in Australia. The ACA was--and remains--weakened by a lack of cross-party political consensus. The ACA's performance and its resulting acceptability to the general public will be critical to the Act's future.
Khurana, Atika; Romer, Dan; Betancourt, Laura M.; Brodsky, Nancy L.; Giannetta, Joan M.; Hurt, Hallam
2012-01-01
Aims 1) To evaluate the role of pre-existing weakness in working memory ability (WM) as a risk factor for early alcohol use as mediated by different forms of impulsivity. 2) To assess the adverse effects of progressive alcohol use on variations in WM over time. Design, Setting and Participants A community sample of 358 adolescents [48% males, Meanage(baseline) = 11.4± 0.87 years] from a longitudinal cohort design, assessed annually over four consecutive years with less than 6% attrition. Measurements Repeated assessments were conducted for the following key variables: WM (based on performance on four separate tasks), frequency of alcohol use (AU), and three forms of impulsivity, namely sensation seeking (SS), acting-without-thinking (AWT) and delay discounting (DD). Latent growth curve modeling procedures were used to identify individual trajectories of change for all key variables. Findings Weakness in WM (at baseline) significantly predicted both concurrent alcohol use and increased frequency of use over the four waves (p <.05). This effect was entirely mediated by two forms of impulsivity, AWT and DD, both of which were characterized by underlying weakness in WM. No individual variation was observed in the slopes of WM, which suggests that individual variations in alcohol use were not associated with changes in WM in our early adolescent sample. Conclusions Early adolescent alcohol use may be a consequence of (pre-existing) weaknesses in working memory (WM) rather than a cause of it. Efforts to reduce early alcohol use should consider the distinct roles of different impulsivity dimensions, in addition to WM, as potential targets of intervention. PMID:23033972
NASA Astrophysics Data System (ADS)
Ma, L. D.; Wang, J.; WEI, C.; Kuroiwa, T.; Narukawa, T.; Ito, N.; HIOKI, A.; CHIBA, K.; Yim, Y. H.; Lee, K. S.; Lim, Y. R.; Turk, G. C.; Davis, C. W.; Mester, Z.; Yang, L.; McCooeye, M.; Maxwell, P.; Cankur, O.; Tokman, N.; Coskun, F. G.
2017-01-01
The CCQM-K97 key comparison was organized by the inorganic analysis working group (IAWG) of CCQM as a follow-up to completed pilot study CCQM-P96 and P96.1 to test the abilities of the national metrology institutes to accurately quantitate the mass fraction of arsenobetaine (AsB) in standard solution and in fish tissue. A pilot study CCQM-P133 was parallelized with this key comparison. National Institute of Metrology (NIM), China and National Metrology Institute of Japan (NMIJ) acted as the coordinating laboratories. Six NMIs participated in CCQM-K97 and two institutes participated in CCQM-P133, and all of them submitted the results. Some NMIs submitted more than one results by different methods. The results were in excellent agreement with each other, and obviously better than those of previous P96 and P96.1. Therefore the calibrant which each NMI used was comparable. It shows that the capabilities of some of the participants have been improved after the previous pilot studies. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Applying the Exceptions to the Fair Labor Standards Act to Child Care Workers
ERIC Educational Resources Information Center
Dalton, Jason
2009-01-01
The Fair Labor Standards Act (FLSA) is the primary federal legislation establishing national wage and hour standards. The purpose of the Act is to protect the working class from overwork and underpay by providing non-waivable rights to a minimum wage and a premium pay rate at time and one-half the regular rate of pay for all hours worked over 40…
Dellve, Lotta; Skagert, Katrin; Vilhelmsson, Rebecka
2007-10-01
Despite the acknowledged role of leadership in the psychosocial work environment, few studies focus on how leadership qualities and strategies may act as key processes of importance to positive effects of workplace health promotion (WHP). The aim of this study was to increase knowledge about how leadership qualities and strategies in WHP projects influence employees' long-term work attendance. The 1- and 2-year effect of leadership on the prevalence of long-term work attendance among municipal human service workers (n = 3 275) was analysed using 3-year register-based data on sick leave, questionnaires and a qualitative categorization of each unit. Increased leadership qualities, especially where leaders used rewards, recognition and respect, were associated with higher prevalence of work attendance at follow-up [PR 1.42 (1.20-1.69)]. Leaders' strategies and views on work-related health had a significant impact on increased work attendance in projects that had goals clearly focusing on changeable factors [1.36 (1.11-1.67)], in multi-focused projects [1.60 (1.24-2.04)] and in projects aimed to increase employees' awareness of their health. Workplace health promotion strategies with a single focus on strengthening individual, professional or organizational resources were negatively associated with work attendance. A higher proportion of employee work attendance was also seen in units whose leaders viewed the organization or the society (rather than individual workers) as responsible for the high rate of sick leave. Leadership, WHP strategies and leaders' attitudes towards employee work-related health have importance for implementation processes, as well as affecting employee work attendance. In this study, multi-focused WHP interventions had the largest effect on work attendance.
Platelet activation is a key event in the pathogenesis of streptococcal infections.
Jia, Ming; Xiong, Yuling; Lu, Hua; Li, Ruqing; Wang, Tiantian; Ye, Yanyao; Song, Min; Li, Bing; Jiang, Tianlun; Zhao, Shuming
2015-06-01
Diverse Streptococcus species including Streptococcus Pneumoniae, Sanguis, Gordonii, Mitis and Mutans cause life-threatening conditions including pneumonia, bacteremia and meningitis. These diseases bear a high morbidity and mortality and for this reason, understanding the key events in the pathogenesis of these infections have a great significance in their prevention and/or treatment. Here, we describe as how the activation of the platelets and their affinity to bind to bacterial proteins act as early key events in the pathogenesis of Streptococcal infections.
ERIC Educational Resources Information Center
Philadelphia School District, PA. Office of Research and Evaluation.
This supplement provides a historical summary, for the Philadelphia, Pennsylvania schools, of the key findings in the Annual Evaluations of each Elementary Secondary Education Act Title I project since 1975. The 1977-1978 management information, the key findings for 1975-1976 and 1976-1977, as well as the preliminary findings for 1977-1978 are…
Recommendations to the Clean Air Act Advisory Committee by Air Quality Management Work Group addressing the recommendations made by the National Research Council to improve the U.S. air quality management system.
Forensic Assertive Community Treatment: A Review of the Literature.
Marquant, Thomas; Sabbe, Bernard; Van Nuffel, Meike; Goethals, Kris
2016-11-01
An extensive body of literature provides evidence supporting the effectiveness of assertive community treatment (ACT) with regard to non-forensic outcome measures, such as number of hospital admissions and length of stay. However, research findings on the effectiveness of ACT for forensic outcome measures, such as rearrests or detentions, is much less clear. The present review, therefore, focuses on the application of ACT in forensic populations, combining key elements of ACT with elements of forensic rehabilitation models. Specifically, a review of the literature was conducted using a systematic methodology in an attempt to combine evidence-based elements of 40 years of research on regular ACT with elements of forensic rehabilitation models. Results reveal limited yet promising evidence in support of the effectiveness of forensic ACT for forensic outcome measures. Implications for future research and clinical practice are discussed.
Dental students' part-time jobs in dental practices in the Netherlands.
Poorterman, J H G; Dikkes, B T; Brand, H S
2010-08-01
In the Netherlands, the Individual Health Care Professions Act (IHCP Act) allows dental students, amongst other non-qualified individuals, to work under certain conditions in a dental practice. The aim of the study was to determine how many dental students have part-time employment in dental practice and which professional tasks they carry out. We also asked the dental students their opinion about the IHCP Act. All the enrolled dental students at the Academic Centre for Dentistry Amsterdam (ACTA) in the Netherlands received a questionnaire by e-mail. Within 1 month, two reminders were sent. The response was 44% (427 students). Of the responding students, 71% had paid employment in addition to their study. Twenty-five per cent of all students worked in a dental practice, usually 8 h a week. Study year and age were positively related to working part-time in dental practice. Activities frequently performed were providing chair side assistance, giving oral hygiene instruction, fluoride applications, scaling and root planning. The self-reported knowledge about the IHCP Act was positively related to study year and working in a dental practice. Hardly any information about the requirements of the IHCP Act with regard to delegation of tasks was provided by the employer. Many Dutch dental students work in a dental practice, taking over a variety of tasks. Although the self-reported knowledge about the IHCP Act was relatively high, many dental students expressed the need for more detailed information about the legal aspects of their tasks.
Portillo, Mari Carmen; Regaira, Elena; Pumar-Méndez, María J; Mujika, Agurtzane; Vassilev, Ivaylo; Rogers, Anne; Wensing, Michel; Foss, Christina; Ruud Knutsen, Ingrid; Todorova, Elka; Roukova, Poli; Kennedy, Anne; Serrano, Manuel; Lionis, Christos; Angelaki, Agapi; Patelarou, Evridiki; Koetsenruijter, Jan
2015-10-01
The purpose of this study is to critically review the literature on the role and work of voluntary organizations and community groups and volunteers in diabetes self-management programs. It seeks to explain how these organizations are located and could be integrated further within a broader system of support. A critical interpretative synthesis of the literature was undertaken as part of the conceptual development of a European research project. Evidence (2000-November 2014) was searched in databases, with the use of key terms, and limited to the languages of the participating countries. This was supplemented by an additional hand search and snowballing technique. A total of 21 articles were included in the review. Evidence regarding the involvement of voluntary organizations in diabetes self-management programs mainly related to: the nature and remit of their work, responsibilities, and attributes; key strategies of programs accounting for success; motivations/barriers for engaging in volunteering participation; relationships between volunteers and users; and connections/tensions with formal services. This review has uncovered a range of facets of voluntary organizations and community groups relevant for supporting diabetes self-management such as the context within which they act and the nature of relationships developed with community and health services. The principles of "assistance, support, sharing, and link" seem essential for this voluntary initiative in self-management to establish effective reciprocal collaboration with health professionals. © 2015 The Author(s).
Geaney, John H
2004-05-01
This article examines the intersection of workers' compensation laws with the Americans with Disabilities Act (ADA) and the Family and Medical Leave Act (FMLA). Much ADA and FMLA litigation stems from work-related injuries or illnesses. Knowledge of the ADA and FMLA may help prevent workers' compensation cases from resulting in costly employment litigation. Employees who are absent from work for a work-related condition often have rights under other laws, besides workers' compensation laws, such as the ADA and FMLA. Employers need to be cognizant of this while addressing these cases. First, the goals of state workers' compensation laws and the ADA and FMLA are reviewed. Then specific issues involving the intersection of workers' compensation, ADA,and FMLA are discussed.
Salt, Ian P; Hardie, D Grahame
2017-05-26
The AMP-activated protein kinase (AMPK) is a key regulator of cellular and whole-body energy homeostasis, which acts to restore energy homoeostasis whenever cellular energy charge is depleted. Over the last 2 decades, it has become apparent that AMPK regulates several other cellular functions and has specific roles in cardiovascular tissues, acting to regulate cardiac metabolism and contractile function, as well as promoting anticontractile, anti-inflammatory, and antiatherogenic actions in blood vessels. In this review, we discuss the role of AMPK in the cardiovascular system, including the molecular basis of mutations in AMPK that alter cardiac physiology and the proposed mechanisms by which AMPK regulates vascular function under physiological and pathophysiological conditions. © 2017 American Heart Association, Inc.
ERIC Educational Resources Information Center
Spangler, D.
This document is intended to help existing school-to-work (STW) partnerships and the new local work force investment boards understand the opportunities for achieving common ground to better serve youth during implementation of the Workforce Investment Act (WIA) and formation of the new youth councils. The following are among the topics discussed:…
Tosh, J.; Dessein, S.; Buerki, S.; Groeninckx, I.; Mouly, A.; Bremer, B.; Smets, E. F.; De Block, P.
2013-01-01
Background and Aims Previous work on the pantropical genus Ixora has revealed an Afro-Madagascan clade, but as yet no study has focused in detail on the evolutionary history and morphological trends in this group. Here the evolutionary history of Afro-Madagascan Ixora spp. (a clade of approx. 80 taxa) is investigated and the phylogenetic trees compared with several key morphological traits in taxa occurring in Madagascar. Methods Phylogenetic relationships of Afro-Madagascan Ixora are assessed using sequence data from four plastid regions (petD, rps16, rpoB-trnC and trnL-trnF) and nuclear ribosomal external transcribed spacer (ETS) and internal transcribed spacer (ITS) regions. The phylogenetic distribution of key morphological characters is assessed. Bayesian inference (implemented in BEAST) is used to estimate the temporal origin of Ixora based on fossil evidence. Key Results Two separate lineages of Madagascan taxa are recovered, one of which is nested in a group of East African taxa. Divergence in Ixora is estimated to have commenced during the mid Miocene, with extensive cladogenesis occurring in the Afro-Madagascan clade during the Pliocene onwards. Conclusions Both lineages of Madagascan Ixora exhibit morphological innovations that are rare throughout the rest of the genus, including a trend towards pauciflorous inflorescences and a trend towards extreme corolla tube length, suggesting that the same ecological and selective pressures are acting upon taxa from both Madagascan lineages. Novel ecological opportunities resulting from climate-induced habitat fragmentation and corolla tube length diversification are likely to have facilitated species radiation on Madagascar. PMID:24142919
77 FR 20837 - Buy American Exceptions Under the American Recovery and Reinvestment Act of 2009
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-06
... Under the American Recovery and Reinvestment Act of 2009 AGENCY: Office of the Assistant Secretary for... Reinvestment Act of 2009 (Pub. L. 111-05, approved February 17, 2009) (Recovery Act), and implementing guidance... American requirement of the Recovery Act have been determined applicable for work using Capital Fund...
77 FR 53904 - Buy American Exceptions Under the American Recovery and Reinvestment Act of 2009
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-04
... Under the American Recovery and Reinvestment Act of 2009 AGENCY: Office of the Assistant Secretary for... Reinvestment Act of 2009 (Pub. L. 111-05, approved February 17, 2009) (Recovery Act), and implementing guidance... American requirement of the Recovery Act have been determined applicable for work using Capital Fund...
National Institute of Justice (NIJ): technology challenges
NASA Astrophysics Data System (ADS)
Morgan, John S.
2004-09-01
Law enforcement agencies play a key role in protecting the nation from and responding to terrorist attacks. The National Institute of Justice (NIJ) is the focal point for the research, development, test and evaluation of technology for law enforcement. NIJ and the Department of Homeland Security's Directorate of Science & Technology (DHS S&T) have related missions to support research and technology development for public safety. DHS S&T provides law enforcement agencies technology to respond to terrorist threats involving weapons of mass destruction, while NIJ focuses on technologies applicable across the spectrum of law enforcement needs. Investment in C3I technology offers perhaps the greatest potential benefit with respect to improving the ability to law enforcement agencies to respond to all types of crime including terrorist acts. Providing effective communications and information systems remains a key technology challenge, as does providing law enforcement responders accurate information that they can act on. Sensors and surveillance systems can play a key role in identifying terrorists and preventing or effectively responding to a terrorist attack.
van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels
2015-01-01
This article is a response to Nordén and Norlander's 'Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?'[1], in which they assert that 'at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT'. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander's interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT.
20 CFR 404.1034 - Work for an international organization.
Code of Federal Regulations, 2010 CFR
2010-04-01
... international organization entitled to enjoy privileges, exemptions, and immunities as an international organization under the International Organizations Immunities Act (59 Stat. 669), your work is excluded from..., and immunities provided in the International Organizations Immunities Act. (3) The designation must be...
20 CFR 404.1034 - Work for an international organization.
Code of Federal Regulations, 2011 CFR
2011-04-01
... international organization entitled to enjoy privileges, exemptions, and immunities as an international organization under the International Organizations Immunities Act (59 Stat. 669), your work is excluded from..., and immunities provided in the International Organizations Immunities Act. (3) The designation must be...
20 CFR 404.1034 - Work for an international organization.
Code of Federal Regulations, 2012 CFR
2012-04-01
... international organization entitled to enjoy privileges, exemptions, and immunities as an international organization under the International Organizations Immunities Act (59 Stat. 669), your work is excluded from..., and immunities provided in the International Organizations Immunities Act. (3) The designation must be...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-21
... venture. Also, LeCroy Corporation, Chestnut Ridge, NY; and Dow-Key Microwave, Ventura, CA, have withdrawn... Section 6(b) of the Act on March 8, 2001 (66 FR 13971). The last notification was filed with the Department on December 6, 2012. A notice was published in the Federal Register pursuant to Section 6(b) of...
The Every Student Succeeds Act: What It Means for Schools, Systems, and States
ERIC Educational Resources Information Center
Hess, Frederick M., Ed.; Eden, Max, Ed.
2017-01-01
Frederick M. Hess and Max Eden bring together a cross-section of respected academics and journalists to examine key aspects of the Every Student Succeeds Act (ESSA). The Chapters appear on the table of contents as follows: (1) From ESEA to NCLB: The Growth of the Federal Role and the Shift to Accountability (Patrick McGuinn); (2) From NCLB to…
Key Findings from Two Reports on Federal School Improvement Grants by the Center on Education Policy
ERIC Educational Resources Information Center
Center on Education Policy, 2012
2012-01-01
The passage of the American Recovery and Reinvestment Act of 2009 (ARRA), also known as the economic stimulus package, provided an extra $3 billion for school improvement grants (SIGs) under section 1003(g) of Title I of the Elementary and Secondary Education Act. Along with this funding increase, the U.S. Department of Education issued guidance…
The Transnational Idea of University Autonomy and the Reform of the Finnish Universities Act
ERIC Educational Resources Information Center
Piironen, Ossi
2013-01-01
In 2009, the Finnish parliament passed a new Universities Act that aimed to strengthen the institutional autonomy of the country's universities. But why and how did the idea of autonomy come to frame the reform agenda in the overt way it did? In analysing a sample of authoritative policy and strategy papers by the key stakeholders in the higher…
Molecular deformation mechanisms of the wood cell wall material.
Jin, Kai; Qin, Zhao; Buehler, Markus J
2015-02-01
Wood is a biological material with outstanding mechanical properties resulting from its hierarchical structure across different scales. Although earlier work has shown that the cellular structure of wood is a key factor that renders it excellent mechanical properties at light weight, the mechanical properties of the wood cell wall material itself still needs to be understood comprehensively. The wood cell wall material features a fiber reinforced composite structure, where cellulose fibrils act as stiff fibers, and hemicellulose and lignin molecules act as soft matrix. The angle between the fiber direction and the loading direction has been found to be the key factor controlling the mechanical properties. However, how the interactions between theses constitutive molecules contribute to the overall properties is still unclear, although the shearing between fibers has been proposed as a primary deformation mechanism. Here we report a molecular model of the wood cell wall material with atomistic resolution, used to assess the mechanical behavior under shear loading in order to understand the deformation mechanisms at the molecular level. The model includes an explicit description of cellulose crystals, hemicellulose, as well as lignin molecules arranged in a layered nanocomposite. The results obtained using this model show that the wood cell wall material under shear loading deforms in an elastic and then plastic manner. The plastic regime can be divided into two parts according to the different deformation mechanisms: yielding of the matrix and sliding of matrix along the cellulose surface. Our molecular dynamics study provides insights of the mechanical behavior of wood cell wall material at the molecular level, and paves a way for the multi-scale understanding of the mechanical properties of wood. Copyright © 2014 Elsevier Ltd. All rights reserved.
SMG-1 and mTORC1 Act Antagonistically to Regulate Response to Injury and Growth in Planarians
González-Estévez, Cristina; Felix, Daniel A.; Smith, Matthew D.; Paps, Jordi; Morley, Simon J.; James, Victoria; Sharp, Tyson V.; Aboobaker, A. Aziz
2012-01-01
Planarian flatworms are able to both regenerate their whole bodies and continuously adapt their size to nutrient status. Tight control of stem cell proliferation and differentiation during these processes is the key feature of planarian biology. Here we show that the planarian homolog of the phosphoinositide 3-kinase-related kinase (PIKK) family member SMG-1 and mTOR complex 1 components are required for this tight control. Loss of smg-1 results in a hyper-responsiveness to injury and growth and the formation of regenerative blastemas that remain undifferentiated and that lead to lethal ectopic outgrowths. Invasive stem cell hyper-proliferation, hyperplasia, hypertrophy, and differentiation defects are hallmarks of this uncontrolled growth. These data imply a previously unappreciated and novel physiological function for this PIKK family member. In contrast we found that planarian members of the mTOR complex 1, tor and raptor, are required for the initial response to injury and blastema formation. Double smg-1 RNAi experiments with tor or raptor show that abnormal growth requires mTOR signalling. We also found that the macrolide rapamycin, a natural compound inhibitor of mTORC1, is able to increase the survival rate of smg-1 RNAi animals by decreasing cell proliferation. Our findings support a model where Smg-1 acts as a novel regulator of both the response to injury and growth control mechanisms. Our data suggest the possibility that this may be by suppressing mTOR signalling. Characterisation of both the planarian mTORC1 signalling components and another PIKK family member as key regulators of regeneration and growth will influence future work on regeneration, growth control, and the development of anti-cancer therapies that target mTOR signalling. PMID:22479207
da Silva, Marcus Vinicius Pereira; de Araújo, Kizi Mendonça; Sampaio, Ricardo Barros; Moraes, Milton Ozório
2017-01-01
Collaborative networks are of great value for science and technology (S&T) institutions as a way of sharing, generating and disseminating new knowledge that could ultimately lead to innovations. Driven by the need to assess the contribution and effectiveness of these networks in informing S&T management, we explored the evolution and dynamics of tuberculosis scientific networks involving the Oswaldo Cruz Foundation (Fiocruz), the major public health S&T Institution in Brazil. Social network analysis (SNA) was used to produce a 10-year (2005–2009, 2010–2014) retrospective longitudinal mapping of Brazilian tuberculosis research networks within the country and internationally, highlighting Fiocruz collaborations. Co-authorship analysis showed a significant expansion of collaboration in Brazil and the role of Fiocruz and other leading national institutions in maintaining connectivity, facilitating knowledge exchange and reducing network vulnerability. It also identified influential researchers that can act as information leaders and support strategic decisions. When we focused on networks inside the institution, the analysis showed a clear discontinuation between the clinical and the public health research areas, which needs specific internal policies to improve collaborations since outcomes in TB are expected to provide better diagnostic tools and more effective treatments. The approach provides evidence to support S&T management by pinpointing: key central institutions maintaining network connectivity; most influential researchers that can act as advisors/experts for investment and induction policies; key Fiocruz researchers that could improve information exchange, systems integration and innovation within the institution; opportunities for synergy between internal research groups working in complementary areas. In summary, we observed that SNA parameters proved to be a valuable tool that, along with other indicators, can strengthen knowledge platforms to support S&T management efforts. PMID:28792514
Life Events: A Complex Role In The Timing Of Suicidal Behavior Among Depressed Patients
Oquendo, Maria A.; Perez-Rodriguez, M. Mercedes; Poh, Ernest; Sullivan, Gregory; Burke, Ainsley K.; Sublette, M. Elizabeth; Mann, J. John; Galfalvy, Hanga
2013-01-01
Suicidal behavior is often conceptualized as a response to overwhelming stress. Our model posits that given a propensity for acting on suicidal urges, stressors such as life events or major depressive episodes (MDEs) determine the timing of suicidal acts. Depressed patients (n=415) were assessed prospectively for suicide attempts and suicide, life events and MDE over 2 years. Longitudinal data was divided into 1-month intervals characterized by MDE (yes/no), suicidal behavior (yes/no), and life event scores. Marginal logistic regression models were fit, with suicidal behavior as the response variable and MDE and life event score in either the same or previous month, respectively, as time-varying covariates. Among 7843 person-months, 33% had MDE and 73% had life events. MDE increased risk for suicidal behavior (OR=4.83, p< 0.0001). Life event scores were unrelated to the timing of suicidal behavior (OR=1.06 per 100 point increase, p=0.32), even during an MDE (OR=1.12, p=0.15). However, among those without Borderline Personality Disorders (BPD), both health and work related life events were key precipitants, as was recurrent MDE, with a 13-fold effect. The relationship of life events to suicidal behavior among those with BPD was more complex. Recurrent MDE was a robust precipitant for suicidal behavior, regardless of BPD comorbidity. The specific nature of life events is key to understanding the timing of suicidal behavior. Given unanticipated results regarding the role of BPD and study limitations, these findings require replication. Of note, that MDE, a treatable risk factor, strongly predicts suicidal behaviors is cause for hope. PMID:24126928
Monitoring the compliance of the academic enterprise with the Fair Labor Standards Act
Bankston, Adriana; McDowell, Gary S.
2017-01-01
Background: On December 1, 2016, the Fair Labor Standards Act (FLSA) was due to be updated by the U.S. Department of Labor. Key changes included an increase in the salary threshold for exemption from overtime for working more than 40 hours per week, and indexing the salary level so that it is updated automatically every 3 years. This was predicted to have a profound effect on academe as postdoctoral researchers were mostly paid at a salary below the new threshold. On November 22, 2016, an injunction was granted nationwide, delaying implementation of the updates, which were finally struck down entirely on August 31, 2017. Here we review the key changes to the FLSA, how they came about, and how the postdoctoral population was affected. Methods: We describe recent data collection efforts to uncover what institutions with postdocs were doing to comply with the FLSA. Results: Our data showed that 57% of institutions checked (containing 41% of the estimated postdoctoral workforce in science, engineering and health) had not decided or had no public decision available one month prior to implementation, and only 35.5% of institutions were planning to raise salaries to the new minimum. After the injunction, a number of institutions and the NIH continued with their plans to raise salaries. Overall, despite the removal of a federal mandate, approximately 60% of postdocs are at institutions whose policy is to raise salaries. Conclusions: Our data show uncertainty in postdoctoral salaries in the U.S. prior to implementation of the FLSA ruling. In addition, while some institutions did suspend plans to raise postdoctoral salaries after the injunction, many continued with the raise. The implementation of postdoctoral salary raises may be inconsistent, however, as the legal minimum is still $23,660. PMID:27990268
Rushton, Carole; Edvardsson, David
2018-04-01
Key commentators on person-centred care have described it as a "new ethic of care" which they link inextricably to notions of individual autonomy, action, change and improvement. Two key points are addressed in this article. The first is that few discussions about ethics and person-centred are underscored by any particular ethical theory. The second point is that despite the espoused benefits of person-centred care, delivery within the acute care setting remains largely aspirational. Choices nurses make about their practice tend to comply more often with prevailing norms than those championed by person-centred care. We draw on elements of work by moral philosopher Løgstrup and Foucault to provide insight into nurses' ethical conduct and ask why nurses would want to act otherwise, when what they think and do is viewed as normal, or think and act otherwise if doing so is seen within the organization as transgressive? To address these more specific questions, we discuss them in relation to the following constructs: the ethical demand, sovereign expressions of life and parrhêsia. We conclude by arguing that a ethical theoretical framework enables nurses to increase their perceptibility and appreciation of the ethical demand particularly those emanating from incommensurability between organizational norms and the norms invoked by person-centred care. We argue that nurses' responses to the ethical demand by way of parrhêsia can be an important feature of intra-organizational reflexivity and its transformation towards the delivery care that is more person-centred, particularly for older people with cognitive impairment. We conclude the article by highlighting the implications of this for nursing education and research. © 2017 John Wiley & Sons Ltd.
Ecological Risk Assessment of Munitions Compounds on Coral and Coral Reef Health
2014-01-01
C308R Porites lobata Maunalua Bay, Oahu, HI K5 TAG GTG GGG AAT CAA ACG GC C307F C309F Porites lobata La Perouse, Maui, HI 3-3 GCT GGC TTA CAG...GGA ATT TTA ACT TCA AGC 24 41.7% 54°C 2.08 Kb this work Porites mtDNA cobR A GAT TCT CTT TGC GCA GTG GCA TAG G 25 52.0% 59°C this work Porites mtDNA...47.6% 52°C 2.14 Kb this work Porites mtDNA nad5(5’)R K CCA ACT GTG CAG ACT TTC CAA CC 23 52.2% 57°C this work References and further reading
ACTS Satellite Telemammography Network Experiments
NASA Technical Reports Server (NTRS)
Kachmar, Brian A.; Kerczewski, Robert J.
2000-01-01
The Satellite Networks and Architectures Branch of NASA's Glenn Research Center has developed and demonstrated several advanced satellite communications technologies through the Advanced Communications Technology Satellite (ACTS) program. One of these technologies is the implementation of a Satellite Telemammography Network (STN) encompassing NASA Glenn, the Cleveland Clinic Foundation. the University of Virginia, and the Ashtabula County Medical Center. This paper will present a look at the STN from its beginnings to the impact it may have on future telemedicine applications. Results obtained using the experimental ACTS satellite demonstrate the feasibility of Satellite Telemammography. These results have improved teleradiology processes and mammography image manipulation, and enabled advances in remote screening methodologies. Future implementation of satellite telemammography using next generation commercial satellite networks will be explored. In addition, the technical aspects of the project will be discussed, in particular how the project has evolved from using NASA developed hardware and software to commercial off the shelf (COTS) products. Development of asymmetrical link technologies was an outcome of this work. Improvements in the display of digital mammographic images, better understanding of end-to-end system requirements, and advances in radiological image compression were achieved as a result of the research. Finally, rigorous clinical medical studies are required for new technologies such as digital satellite telemammography to gain acceptance in the medical establishment. These experiments produced data that were useful in two key medical studies that addressed the diagnostic accuracy of compressed satellite transmitted digital mammography images. The results of these studies will also be discussed.
Purines and neuronal excitability: links to the ketogenic diet.
Masino, S A; Kawamura, M; Ruskin, D N; Geiger, J D; Boison, D
2012-07-01
ATP and adenosine are purines that play dual roles in cell metabolism and neuronal signaling. Acting at the A(1) receptor (A(1)R) subtype, adenosine acts directly on neurons to inhibit excitability and is a powerful endogenous neuroprotective and anticonvulsant molecule. Previous research showed an increase in ATP and other cell energy parameters when an animal is administered a ketogenic diet, an established metabolic therapy to reduce epileptic seizures, but the relationship among purines, neuronal excitability and the ketogenic diet was unclear. Recent work in vivo and in vitro tested the specific hypothesis that adenosine acting at A(1)Rs is a key mechanism underlying the success of ketogenic diet therapy and yielded direct evidence linking A(1)Rs to the antiepileptic effects of a ketogenic diet. Specifically, an in vitro mimic of a ketogenic diet revealed an A(1)R-dependent metabolic autocrine hyperpolarization of hippocampal neurons. In parallel, applying the ketogenic diet in vivo to transgenic mouse models with spontaneous electrographic seizures revealed that intact A(1)Rs are necessary for the seizure-suppressing effects of the diet. This is the first direct in vivo evidence linking A(1)Rs to the antiepileptic effects of a ketogenic diet. Other predictions of the relationship between purines and the ketogenic diet are discussed. Taken together, recent research on the role of purines may offer new opportunities for metabolic therapy and insight into its underlying mechanisms. Copyright © 2011 Elsevier B.V. All rights reserved.
Liebers, Falk; Brandstädt, Felix; Schust, Marianne; Serafin, Patrick; Schäfer, Andreas; Gebhardt, Hansjürgen; Hartmann, Bernd; Steinberg, Ulf
2017-01-01
Introduction The impact of work-related musculoskeletal disorders is considerable. The assessment of work tasks with physical workloads is crucial to estimate the work-related health risks of exposed employees. Three key indicator methods are available for risk assessment regarding manual lifting, holding and carrying of loads; manual pulling and pushing of loads; and manual handling operations. Three further KIMs for risk assessment regarding whole-body forces, awkward body postures and body movement have been developed de novo. In addition, the development of a newly drafted combined method for mixed exposures is planned. All methods will be validated regarding face validity, reliability, convergent validity, criterion validity and further aspects of utility under practical conditions. Methods and analysis As part of the joint project MEGAPHYS (multilevel risk assessment of physical workloads), a mixed-methods study is being designed for the validation of KIMs and conducted in companies of different sizes and branches in Germany. Workplaces are documented and analysed by observations, applying KIMs, interviews and assessment of environmental conditions. Furthermore, a survey among the employees at the respective workplaces takes place with standardised questionnaires, interviews and physical examinations. It is intended to include 1200 employees at 120 different workplaces. For analysis of the quality criteria, recommendations of the COSMIN checklist (COnsensus-based Standards for the selection of health Measurement INstruments) will be taken into account. Ethics and dissemination The study was planned and conducted in accordance with the German Medical Professional Code and the Declaration of Helsinki as well as the German Federal Data Protection Act. The design of the study was approved by ethics committees. We intend to publish the validated KIMs in 2018. Results will be published in peer-reviewed journals, presented at international meetings and disseminated to actual users for practical application. PMID:28827239
Klussmann, Andre; Liebers, Falk; Brandstädt, Felix; Schust, Marianne; Serafin, Patrick; Schäfer, Andreas; Gebhardt, Hansjürgen; Hartmann, Bernd; Steinberg, Ulf
2017-08-21
The impact of work-related musculoskeletal disorders is considerable. The assessment of work tasks with physical workloads is crucial to estimate the work-related health risks of exposed employees. Three key indicator methods are available for risk assessment regarding manual lifting, holding and carrying of loads; manual pulling and pushing of loads; and manual handling operations. Three further KIMs for risk assessment regarding whole-body forces, awkward body postures and body movement have been developed de novo. In addition, the development of a newly drafted combined method for mixed exposures is planned. All methods will be validated regarding face validity, reliability, convergent validity, criterion validity and further aspects of utility under practical conditions. As part of the joint project MEGAPHYS (multilevel risk assessment of physical workloads), a mixed-methods study is being designed for the validation of KIMs and conducted in companies of different sizes and branches in Germany. Workplaces are documented and analysed by observations, applying KIMs, interviews and assessment of environmental conditions. Furthermore, a survey among the employees at the respective workplaces takes place with standardised questionnaires, interviews and physical examinations. It is intended to include 1200 employees at 120 different workplaces. For analysis of the quality criteria, recommendations of the COSMIN checklist (COnsensus-based Standards for the selection of health Measurement INstruments) will be taken into account. The study was planned and conducted in accordance with the German Medical Professional Code and the Declaration of Helsinki as well as the German Federal Data Protection Act. The design of the study was approved by ethics committees. We intend to publish the validated KIMs in 2018. Results will be published in peer-reviewed journals, presented at international meetings and disseminated to actual users for practical application. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
The Mental Capacity Act 2007 and capacity assessments: a guide for the non-psychiatrist.
Mukherjee, Elora; Foster, Russell
2008-02-01
The Mental Capacity Act 2007 affects doctors in all areas of practice. The act recognises that capacity is a 'balance of probability rather than certainty', and based on this it attempts to 'maximise capacity' in an individual, so to facilitate a decision-making process. The act comprises five key principles as well as a test to determine lack of capacity. It also alludes to areas such as consent by proxy, restraint and capacity, and regulations regarding clinical research. This paper provides a brief background into the fundamental tenets of the act as well as a simple scheme for assessing capacity in hospital inpatients. It also looks at what physicians should be aware of and what will be required of them, particularly from a medico-legal perspective.
32 CFR 324.4 - Responsibilities.
Code of Federal Regulations, 2014 CFR
2014-07-01
... levels, and contractor personnel working with personal data comply with the DFAS Privacy Act Program. (2... personnel and contractors working with personal data comply with the Privacy Act Program. (2) Serves as the... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM...
Cheung, Francis Y L; Lun, Vivian Miu-Chi
2015-01-01
This study examined the association between emotional labor and organizational citizenship behavior (OCB) and the mediation of work engagement in this relationship. A total of 264 teachers in Mainland China were recruited for this study. Bivariate correlation showed that both deep acting and the expression of naturally felt emotion were positively related to the two dimensions of OCB, namely, OCB toward the individual (OCBI) and OCB toward the organization (OCBO), whereas surface acting was not related to the OCB dimensions. Work engagement was also positively associated with both OCB dimensions. Regression results showed that work engagement partially mediated the relation between deep acting and OCBO, and that between the expression of naturally felt emotion and OCBI. Work engagement also fully mediated the association between deep acting and OCBI, and that between the expression of naturally felt emotion and OCBO. In light of these findings, strategies that encourage employees to display emotions consistent with their inner experience were discussed.
Droplet swimmers in complex geometries: Autochemotaxis and trapping at pillars.
NASA Astrophysics Data System (ADS)
Maass, Corinna; Jin, Chenyu; Krueger, Carsten; Vajdi Hokmabad, Babak
Autochemotaxis is a key feature of communication between microorganisms, via their emission of a slowly diffusing chemoattractant or repellent. We present a well-controlled, tunable artificial model to study autochemotaxis in complex geometries, using microfluidic assays of self-propelling liquid crystal droplets in an aqueous surfactant solution. Droplets gain propulsion energy by micellar solubilisation, with filled micelles acting as a chemical repellent by diffusive phoretic gradient forces. We can tune the key parameters swimmer size, velocity and persistence length. If a swimming droplet approaches a wall, it will provide a boundary to both the hydrodynamic flow field and the spread of phoretic gradients, determining the interaction between swimmer and wall. Pillar arrays of variable sizes and shapes provide a convex wall interacting with the swimmer and in the case of attachment bending its trajectory and forcing it to revert to its own trail. We observe different behavior based on the interplay of wall curvature and negative auto-chemotaxis, i. e., no attachment for highly curved interfaces, stable trapping at large pillars, and a narrow transition region where negative autochemotaxis makes the swimmers detach after a single orbit. Work funded by the DFG SPP 1726 ''Microswimmers''.
Calibrating the system dynamics of LISA Pathfinder
NASA Astrophysics Data System (ADS)
Armano, M.; Audley, H.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Castelli, E.; Cavalleri, A.; Cesarini, A.; Cruise, A. M.; Danzmann, K.; de Deus Silva, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E. D.; Freschi, M.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Grzymisch, J.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C. J.; Lobo, J. A.; Lloro, I.; Liu, L.; López-Zaragoza, J. P.; Maarschalkerweerd, R.; Mance, D.; Meshksar, N.; Martín, V.; Martin-Polo, L.; Martino, J.; Martin-Porqueras, F.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mendes, L.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Ramos-Castro, J.; Reiche, J.; Robertson, D. I.; Rivas, F.; Russano, G.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J. I.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Wass, P.; Weber, W. J.; Wissel, L.; Wittchen, A.; Zweifel, P.
2018-06-01
LISA Pathfinder (LPF) was a European Space Agency mission with the aim to test key technologies for future space-borne gravitational-wave observatories like LISA. The main scientific goal of LPF was to demonstrate measurements of differential acceleration between free-falling test masses at the sub-femto-g level, and to understand the residual acceleration in terms of a physical model of stray forces, and displacement readout noise. A key step toward reaching the LPF goals was the correct calibration of the dynamics of LPF, which was a three-body system composed by two test-masses enclosed in a single spacecraft, and subject to control laws for system stability. In this work, we report on the calibration procedures adopted to calculate the residual differential stray force per unit mass acting on the two test-masses in their nominal positions. The physical parameters of the adopted dynamical model are presented, together with their role on LPF performance. The analysis and results of these experiments show that the dynamics of the system was accurately modeled and the dynamical parameters were stationary throughout the mission. Finally, the impact and importance of calibrating system dynamics for future space-based gravitational wave observatories is discussed.
NASA Astrophysics Data System (ADS)
Morgan, John S.
2005-05-01
Law enforcement agencies play a key role in protecting the nation from and responding to terrorist attacks. Preventing terrorism and promoting the nation"s security is the Department of Justice"s number one strategic priority. This is reflected in its technology development efforts, as well as its operational focus. The National Institute of Justice (NIJ) is the national focal point for the research, development, test and evaluation of technology for law enforcement. In addition to its responsibilities in supporting day-to-day criminal justice needs in areas such as less lethal weapons and forensic science, NIJ also provides critical support for counter-terrorism capacity improvements in state and local law enforcement in several areas. The most important of these areas are bomb response, concealed weapons detection, communications and information technology, which together offer the greatest potential benefit with respect to improving the ability to law enforcement agencies to respond to all types of crime including terrorist acts. NIJ coordinates its activities with several other key federal partners, including the Department of Homeland Security"s Science and Technology Directorate, the Technical Support Working Group, and the Department of Defense.
De Martino, Marco; Azzariti, Amalia; Arra, Claudio; Fusco, Alfredo; Esposito, Francesco
2017-01-01
Several studies have established that pseudogene mRNAs can work as competing endogenous RNAs and, when deregulated, play a key role in the onset of human neoplasias. Recently, we have isolated two HMGA1 pseudogenes, HMGA1P6 and HMGA1P7. These pseudogenes have a critical role in cancer progression, acting as micro RNA (miRNA) sponges for HMGA1 and other cancer-related genes. HMGA1 pseudogenes were found overexpressed in several human carcinomas, and their expression levels positively correlate with an advanced cancer stage and a poor prognosis. In order to investigate the molecular alterations following HMGA1 pseudogene 7 overexpression, we carried out miRNA sequencing analysis on HMGA1P7 overexpressing mouse embryonic fibroblasts. Intriguingly, the most upregulated miRNAs were miR-483 and miR-675 that have been described as key regulators in cancer progression. Here, we report that HMGA1P7 upregulates miR-483 and miR-675 through a competing endogenous RNA mechanism with Egr1, a transcriptional factor that positively regulates miR-483 and miR-675 expression. PMID:29149041
NASA Astrophysics Data System (ADS)
Teller, Sara; Tahirbegi, Islam Bogachan; Mir, Mònica; Samitier, Josep; Soriano, Jordi
2015-11-01
The understanding of the key mechanisms behind human brain deterioration in Alzheimer’ disease (AD) is a highly active field of research. The most widespread hypothesis considers a cascade of events initiated by amyloid-β peptide fibrils that ultimately lead to the formation of the lethal amyloid plaques. Recent studies have shown that other agents, in particular magnetite, can also play a pivotal role. To shed light on the action of magnetite and amyloid-β in the deterioration of neuronal circuits, we investigated their capacity to alter spontaneous activity patterns in cultured neuronal networks. Using a versatile experimental platform that allows the parallel monitoring of several cultures, the activity in controls was compared with the one in cultures dosed with magnetite, amyloid-β and magnetite-amyloid-β complex. A prominent degradation in spontaneous activity was observed solely when amyloid-β and magnetite acted together. Our work suggests that magnetite nanoparticles have a more prominent role in AD than previously thought, and may bring new insights in the understanding of the damaging action of magnetite-amyloid-β complex. Our experimental system also offers new interesting perspectives to explore key biochemical players in neurological disorders through a controlled, model system manner.
Legislative Alphabet Soup: Federal Laws that Affect Your Work as a Library Media Specialist
ERIC Educational Resources Information Center
Adams, Helen R.
2006-01-01
Today, federal laws often seem like an alphabet soup with acronyms like CIPA (Children's Internet Protection Act), CTEA (Copyright Term Extension Act), ADA (Americans with Disabilities Act), IDEA (Individuals with Disabilities Education Act), YMCA (Digital Millennium Copyright Act), and NC LB (No Child Left Behind). These letters stand for federal…
10 CFR 1008.7 - Processing of requests.
Code of Federal Regulations, 2011 CFR
2011-01-01
... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) RECORDS MAINTAINED ON INDIVIDUALS (PRIVACY ACT) Requests for Access....6 shall be promptly acknowledged by the Privacy Act Officer. (b) Each request shall be acted upon... Manager or designee. If a response cannot be made within ten working days, the appropriate Privacy Act...
The Changing Face of Immigration Law.
ERIC Educational Resources Information Center
Nugent, Christopher
2001-01-01
Focuses on laws that influence U.S. immigration, such as the Illegal Immigration Reform and Immigrant Responsibility Act (1996), the Personal Responsibility and Work Opportunity Reconciliation Act (1996), the Anti-Terrorism and Effective Death Penalty Act (1996), and the Legal Immigration and Family Equity Act (2000). Includes discussion…
Alvarez, Renae; Ginsburg, Jacob; Grabowski, Jessica; Post, Sharon; Rosenberg, Walter
2016-04-01
The hospital experience is taxing and confusing for patients and their families, particularly those with limited economic and social resources. This complexity often leads to disengagement, poor adherence to the plan of care, and high readmission rates. Novel approaches to addressing the complexities of transitional care are emerging as possible solutions. The Bridge Model is a person-centered, social work-led, interdisciplinary transitional care intervention that helps older adults safely transition from the hospital back to their homes and communities. The Bridge Model combines 3 key components-care coordination, case management, and patient engagement-which provide a seamless transition during this stressful time and improve the overall quality of transitional care for older adults, including reducing hospital readmissions. The post Affordable Care Act (ACA) and managed care environment's emphasis on value and quality support further development and expansion of transitional care strategies, such as the Bridge Model, which offer promising avenues to fulfil the triple aim by improving the quality of individual patient care while also impacting population health and controlling per capita costs.
A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence
Connolly, James P. R.; Gabrielsen, Mads; Goldstone, Robert J.; Grinter, Rhys; Wang, Dai; Cogdell, Richard J.; Walker, Daniel; Smith, David G. E.; Roe, Andrew J.
2016-01-01
The ability of any organism to sense and respond to challenges presented in the environment is critically important for promoting or restricting colonization of specific sites. Recent work has demonstrated that the host metabolite D-serine has the ability to markedly influence the outcome of infection by repressing the type III secretion system of enterohaemorrhagic Escherichia coli (EHEC) in a concentration-dependent manner. However, exactly how EHEC monitors environmental D-serine is not understood. In this work, we have identified two highly conserved members of the E. coli core genome, encoding an inner membrane transporter and a transcriptional regulator, which collectively help to “sense” levels of D-serine by regulating its uptake from the environment and in turn influencing global gene expression. Both proteins are required for full expression of the type III secretion system and diversely regulated prophage-encoded effector proteins demonstrating an important infection-relevant adaptation of the core genome. We propose that this system acts as a key safety net, sampling the environment for this metabolite, thereby promoting colonization of EHEC to favorable sites within the host. PMID:26727373
Solar Radiation Management and Olivine Dissolution Methods in Climate Engineering
NASA Astrophysics Data System (ADS)
Kone, S.
2014-12-01
An overview of solar radiation management and olivine dissolution methods allows to discuss, comparatively, the benefits and consequences of these two geoengineering techniques. The combination of those two techniques allows to concomitantly act on the two main agents intervening in global warming: solar radiation and carbon dioxide. The earth surface temperature increases due mainly to carbon dioxide (a greenhouse gas) that keeps the solar radiation and causes the global warming. Two complementary methods to mitigate climate change are overviewed: SRM method, which uses injected aerosols, aims to reduce the amount of the inbound solar radiation in atmosphere; and olivine dissolution in water, a key chemical reaction envisaged in climate engineering , aiming to reduce the amount of the carbon dioxide in extracting it from atmosphere. The SRM method works on scenarios of solar radiation decrease and the olivine dissolution method works as a carbon dioxide sequestration method. Olivine dissolution in water impacts negatively on the pH of rivers but positively in counteracting ocean acidification and in transporting the silica in ocean, which has benefits for diatom shell formation.
Particle Generation and Evolution in Silane/Acetylene Flames in Microgravity
NASA Technical Reports Server (NTRS)
Keil, D. G.
2001-01-01
The objective of this new experimental program is to advance the understanding of the formation of particles from gas phase combustion processes. The work will utilize the unique SiH4/C2H2 combustion system which generates particulate products ranging from high purity, white SiC to carbonaceous soot depending on equivalence ratio. A key goal of this work is to identify gas phase or particle formation processes that provide the enthalpy release necessary to drive the combustion wave, and to locate the parts of the particle formation process that determine SiC stoichiometry and crystallinity. In a real sense, these SiH4/C2H2 flames act like "highly sooty" hydrocarbon flames, but with simpler chemistry. This simplification is expected to allow them to be used as surrogates to advance understanding of soot formation in such rich hydrocarbon flames. It is also expected that this improved understanding of SiC particle generation and evolution in these self-sustaining flames will advance the commercial potential of the flame process for the generation of high purity SiC powders.
The Imperative of Solving Nurses' Usability Problems With Health Information Technology.
Staggers, Nancy; Elias, Beth L; Makar, Ellen; Alexander, Gregory L
2018-04-01
Health information technology (IT) usability issues are a key concern for nurse executives and nurses. The aims of this study are to understand usability pain points faced by nurses regarding the use of health IT, identify their impact and importance, discuss responsibilities, and develop possible solutions to improve the health IT-user experience for nurses. Twenty-seven experts were interviewed including nursing leaders, informaticists, executives, engineers, researchers, and human factors experts across acute care, long-term care, and vendor settings. Semistructured questions guided the interviews, and content analysis was used to identify themes. Four themes emerged: 1) user experience pain points, 2) importance of the issues, 3) the responsibility gap, and 4) acting on usability issues. Nurses continue to endure significant health IT-usability issues that negatively impact patients, nurses, and healthcare organizations. Solutions include enhancing the voice of nursing at the national and local levels, creating a digital strategy for nursing, providing incentives to improve usability in health IT, and accelerating the understanding of nurses' work intended to inform and translate nurses' work into health IT design.
Contributing factors in construction accidents.
Haslam, R A; Hide, S A; Gibb, A G F; Gyi, D E; Pavitt, T; Atkinson, S; Duff, A R
2005-07-01
This overview paper draws together findings from previous focus group research and studies of 100 individual construction accidents. Pursuing issues raised by the focus groups, the accident studies collected qualitative information on the circumstances of each incident and the causal influences involved. Site based data collection entailed interviews with accident-involved personnel and their supervisor or manager, inspection of the accident location, and review of appropriate documentation. Relevant issues from the site investigations were then followed up with off-site stakeholders, including designers, manufacturers and suppliers. Levels of involvement of key factors in the accidents were: problems arising from workers or the work team (70% of accidents), workplace issues (49%), shortcomings with equipment (including PPE) (56%), problems with suitability and condition of materials (27%), and deficiencies with risk management (84%). Employing an ergonomics systems approach, a model is proposed, indicating the manner in which originating managerial, design and cultural factors shape the circumstances found in the work place, giving rise to the acts and conditions which, in turn, lead to accidents. It is argued that attention to the originating influences will be necessary for sustained improvement in construction safety to be achieved.
ERIC Educational Resources Information Center
Mengoni, Silvana; Bardsley, Janet; Oates, John
2015-01-01
Key working is a way of supporting children and young people with special educational needs and disabilities (SEND) and their families, and is highly regarded by families and practitioners. However, there is a lack of up-to-date research exploring key working in the current context of policy reforms in England. This article reports an evaluation…
Modular assembly of optical nanocircuits.
Shi, Jinwei; Monticone, Francesco; Elias, Sarah; Wu, Yanwen; Ratchford, Daniel; Li, Xiaoqin; Alù, Andrea
2014-05-29
A key element enabling the microelectronic technology advances of the past decades has been the conceptualization of complex circuits with versatile functionalities as being composed of the proper combination of basic 'lumped' circuit elements (for example, inductors and capacitors). In contrast, modern nanophotonic systems are still far from a similar level of sophistication, partially because of the lack of modularization of their response in terms of basic building blocks. Here we demonstrate the design, assembly and characterization of relatively complex photonic nanocircuits by accurately positioning a number of metallic and dielectric nanoparticles acting as modular lumped elements. The nanoparticle clusters produce the desired spectral response described by simple circuit rules and are shown to be dynamically reconfigurable by modifying the direction or polarization of impinging signals. Our work represents an important step towards extending the powerful modular design tools of electronic circuits into nanophotonic systems.
Modular assembly of optical nanocircuits
NASA Astrophysics Data System (ADS)
Shi, Jinwei; Monticone, Francesco; Elias, Sarah; Wu, Yanwen; Ratchford, Daniel; Li, Xiaoqin; Alù, Andrea
2014-05-01
A key element enabling the microelectronic technology advances of the past decades has been the conceptualization of complex circuits with versatile functionalities as being composed of the proper combination of basic ‘lumped’ circuit elements (for example, inductors and capacitors). In contrast, modern nanophotonic systems are still far from a similar level of sophistication, partially because of the lack of modularization of their response in terms of basic building blocks. Here we demonstrate the design, assembly and characterization of relatively complex photonic nanocircuits by accurately positioning a number of metallic and dielectric nanoparticles acting as modular lumped elements. The nanoparticle clusters produce the desired spectral response described by simple circuit rules and are shown to be dynamically reconfigurable by modifying the direction or polarization of impinging signals. Our work represents an important step towards extending the powerful modular design tools of electronic circuits into nanophotonic systems.
Acoustic field modulation in regenerators
NASA Astrophysics Data System (ADS)
Hu, J. Y.; Wang, W.; Luo, E. C.; Chen, Y. Y.
2016-12-01
The regenerator is a key component that transfers energy between heat and work. The conversion efficiency is significantly influenced by the acoustic field in the regenerator. Much effort has been spent to quantitatively determine this influence, but few comprehensive experimental verifications have been performed because of difficulties in modulating and measuring the acoustic field. In this paper, a method requiring two compressors is introduced and theoretically investigated that achieves acoustic field modulation in the regenerator. One compressor outputs the acoustic power for the regenerator; the other acts as a phase shifter. A RC load dissipates the acoustic power out of both the regenerator and the latter compressor. The acoustic field can be modulated by adjusting the current in the two compressors and opening the RC load. The acoustic field is measured with pressure sensors instead of flow-field imaging equipment, thereby greatly simplifying the experiment.
Lean manufacturing comes to China: a case study of its impact on workplace health and safety.
Brown, Garrett D; O'Rourke, Dara
2007-01-01
Lean manufacturing, which establishes small production "cells," or teams of workers, who complete an entire product from raw material processing through final assembly and shipment, increases health and safety hazards by mixing previously separated exposures to various chemicals (with possible additive and cumulative effects) and noise. The intensification of work leads to greater ergonomic and stress-related adverse health effects, as well as increased safety hazards. The standard industrial hygiene approach of anticipation, recognition, evaluation, and hazard control is applicable to lean operations. A focus on worker participation in identifying and solving problems is critical for reducing negative impacts. A key to worker safety in lean production operations is the development of informed, empowered, and active workers with the knowledge, skills, and opportunity to act in the workplace to eliminate or reduce hazards.
Differentiation in Coregonus zenithicus in Lake Superior
Todd, Thomas N.; Smith, Gerald R.
1980-01-01
Morphological variation in Coregonus zenithicus has long plagued biologists working on Lake Superior ciscoes. Some of this variation is due to allometric growth; earlier workers incorrectly recognized large C. zenithicus as a distinct species, C. nigripinnis cyanopterus. Coregonus reighardi dymondi is a variant of C. zenithicus in northern bays of Lake Superior and Lake Nipigon. The morphological differences between members of spring and fall spawning populations of C. zenithicus in Lake Superior are no greater than those between geographically separate populations. We conclude that spawning time and geographic isolation act similarly in effecting differentiation of coregonine populations, and that populations with different spawning times do not necessarily represent different species.Key words: Coregonus zenithicus, cisco, Great Lakes, multivariate morphometrics, endangered species, taxonomy
29 CFR 5.12 - Debarment proceedings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and... Administrator of the Wage and Hour Division, Employment Standards Administration, U.S. Department of Labor... assisted construction work subject to any of the applicable statutes listed in § 5.1 and other labor...
32 CFR 324.4 - Responsibilities.
Code of Federal Regulations, 2011 CFR
2011-07-01
... levels, and contractor personnel working with personal data comply with the DFAS Privacy Act Program. (2... personnel and contractors working with personal data comply with the Privacy Act Program. (2) Serves as the... identifiable personal information is for a necessary and lawful purpose, that the information is current and...
Dental hygiene students' part-time jobs in dental practices in the Netherlands.
Poorterman, J H G; Dikkes, B T; Brand, H S
2010-05-01
Many students have paid employment while studying. In the Netherlands, the Individual Health Care Professions Act (IHCP Act) allows dental hygiene students to work under certain conditions in a dental practice. The aim of the study was to determine how many dental hygiene students have part-time job employment in dental practice and which professional tasks they carry out. We also asked the dental hygiene students their opinion of the IHCP Act. All the enrolled dental hygiene students (n = 341) at a School of Health in the Netherlands received a questionnaire by email. The response was 52% (176 students). Of the responding students, 75% had paid employment in addition to their study. A proportion of the students (35%) worked in a dental practice. The median number of hours worked per week was eight. Study year, age and prior education were positively related to working part-time in dental practice. Activities frequently performed were giving oral hygiene instruction, fluoride applications, scaling and root planning, providing chair side assistance and giving local anaesthesia. Although the self-reported knowledge about the IHCP Act was high, almost half of the students expressed the need for more detailed legal information. Many dental hygiene students work in a dental practice, taking over a number of tasks usually performed by the dentist. More information in the dental hygiene curriculum about the requirements of the IHCP Act seems desirable.
Photo interpretation key to Michigan land cover/use
NASA Technical Reports Server (NTRS)
Enslin, W. R.; Hudson, W. D.; Lusch, D. P.
1983-01-01
A set of photo interpretation keys is presented to provide a structured approach to the identification of land cover/use categories as specified in the Michigan Resource Inventory Act. The designated categories are urban and; built up lands; agricultural lands; forest land; nonforested land; water bodies; wetlands; and barren land. The keys were developed for use with medium scale (1:20,000 to 1:24,000) color infrared aerial photography. Although each key is generalized in that it relies only upon the most distinguishing photo characteristics in separating the various land cover/use categories, additional interpretation characteristics, distinguishing features and background material are given.
Exemplar Units of Work for English. Key Stage 3: National Strategy.
ERIC Educational Resources Information Center
Department for Education and Skills, London (England).
These exemplar units of work for National Strategy Key Stage 3 English show how medium and short-term planning can be based on the Key Stage 3 Framework objectives and support the implementation of Curriculum 2000. The Key Stage 3 English strand introduces pupils to more specialist study of language and literature and supports the study of…
ACHP | Recovery Act Section 106 Training
Working with Section 106 Federal, State, & Tribal Programs Training & Education Publications Search skip specific nav links Home arrow Training and Education arrow Recovery Act Section 106 Training RECOVERY ACT SECTION 106 TRAINING 2009 Recovery Act Section 106 Seminar Schedule Registration Forms General
ERIC Educational Resources Information Center
Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.
This guide is Unit 3 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to identify the key elements of the United States' nuclear waste dilemma and introduce the Nuclear Waste Policy Act and the role of the…
Modeling Linear and Cyclic PKS Intermediates through Atom Replacement
2015-01-01
The mechanistic details of many polyketide synthases (PKSs) remain elusive due to the instability of transient intermediates that are not accessible via conventional methods. Here we report an atom replacement strategy that enables the rapid preparation of polyketone surrogates by selective atom replacement, thereby providing key substrate mimetics for detailed mechanistic evaluations. Polyketone mimetics are positioned on the actinorhodin acyl carrier protein (actACP) to probe the underpinnings of substrate association upon nascent chain elongation and processivity. Protein NMR is used to visualize substrate interaction with the actACP, where a tetraketide substrate is shown not to bind within the protein, while heptaketide and octaketide substrates show strong association between helix II and IV. To examine the later cyclization stages, we extended this strategy to prepare stabilized cyclic intermediates and evaluate their binding by the actACP. Elongated monocyclic mimics show much longer residence time within actACP than shortened analogs. Taken together, these observations suggest ACP-substrate association occurs both before and after ketoreductase action upon the fully elongated polyketone, indicating a key role played by the ACP within PKS timing and processivity. These atom replacement mimetics offer new tools to study protein and substrate interactions and are applicable to a wide variety of PKSs. PMID:25406716
Passive Joint Forces Are Tuned to Limb Use in Insects and Drive Movements without Motor Activity
Ache, Jan M.; Matheson, Thomas
2013-01-01
Summary Background Limb movements are generally driven by active muscular contractions working with and against passive forces arising in muscles and other structures. In relatively heavy limbs, the effects of gravity and inertia predominate, whereas in lighter limbs, passive forces intrinsic to the limb are of greater consequence. The roles of passive forces generated by muscles and tendons are well understood, but there has been little recognition that forces originating within joints themselves may also be important, and less still that these joint forces may be adapted through evolution to complement active muscle forces acting at the same joint. Results We examined the roles of passive joint forces in insect legs with different arrangements of antagonist muscles. We first show that passive forces modify actively generated movements of a joint across its working range, and that they can be sufficiently strong to generate completely passive movements that are faster than active movements observed in natural behaviors. We further demonstrate that some of these forces originate within the joint itself. In legs of different species adapted to different uses (walking, jumping), these passive joint forces complement the balance of strength of the antagonist muscles acting on the joint. We show that passive joint forces are stronger where they assist the weaker of two antagonist muscles. Conclusions In limbs where the dictates of a key behavior produce asymmetry in muscle forces, passive joint forces can be coadapted to provide the balance needed for the effective generation of other behaviors. PMID:23871240
Robson, Andrew; Robson, Fiona
2015-01-01
To identify the combination of variables that explain nurses' continuation intention in the UK National Health Service. This alternative arena has permitted the replication of a private sector Australian study. This study provides understanding about the issues that affect nurse retention in a sector where employee attrition is a key challenge, further exacerbated by an ageing workforce. A quantitative study based on a self-completion survey questionnaire completed in 2010. Nurses employed in two UK National Health Service Foundation Trusts were surveyed and assessed using seven work-related constructs and various demographics including age generation. Through correlation, multiple regression and stepwise regression analysis, the potential combined effect of various explanatory variables on continuation intention was assessed, across the entire nursing cohort and in three age-generation groups. Three variables act in combination to explain continuation intention: work-family conflict, work attachment and importance of work to the individual. This combination of significant explanatory variables was consistent across the three generations of nursing employee. Work attachment was identified as the strongest marginal predictor of continuation intention. Work orientation has a greater impact on continuation intention compared with employer-directed interventions such as leader-member exchange, teamwork and autonomy. UK nurses are homogeneous across the three age-generations regarding explanation of continuation intention, with the significant explanatory measures being recognizably narrower in their focus and more greatly concentrated on the individual. This suggests that differentiated approaches to retention should perhaps not be pursued in this sectoral context. © 2014 John Wiley & Sons Ltd.
The HESI RISK21 project formed the Dose-Response/Mode-of-Action Subteam to develop strategies for using all available data (in vitro, in vivo, and in silico) to advance the next-generation of chemical risk assessments. A goal of the Subteam is to enhance the existing Mode of Act...
24 CFR 3282.353 - Submission format.
Code of Federal Regulations, 2014 CFR
2014-04-01
... Submission format. States and private organizations that wish to act as primary inspection agencies shall... key personnel who will perform the various functions required under these regulations; (4) The number...
29 CFR 5.12 - Debarment proceedings.
Code of Federal Regulations, 2011 CFR
2011-07-01
... SUBJECT TO THE CONTRACT WORK HOURS AND SAFETY STANDARDS ACT) Davis-Bacon and Related Acts Provisions and... Administrator of the Wage and Hour Division, Employment Standards Administration, U.S. Department of Labor... assisted construction work subject to any of the applicable statutes listed in § 5.1 and other labor...
18 CFR 367.1350 - Account 135, Working funds.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 135, Working funds. 367.1350 Section 367.1350 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE COMPANIES SUBJECT TO...
32 CFR Appendix D to Part 290 - Audit Working Papers
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 2 2013-07-01 2013-07-01 false Audit Working Papers D Appendix D to Part 290 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM Pt...
32 CFR Appendix D to Part 290 - Audit Working Papers
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 2 2010-07-01 2010-07-01 false Audit Working Papers D Appendix D to Part 290 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM Pt...
32 CFR Appendix D to Part 290 - Audit Working Papers
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 2 2012-07-01 2012-07-01 false Audit Working Papers D Appendix D to Part 290 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM Pt...
32 CFR Appendix D to Part 290 - Audit Working Papers
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 2 2011-07-01 2011-07-01 false Audit Working Papers D Appendix D to Part 290 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM Pt...
32 CFR Appendix D to Part 290 - Audit Working Papers
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Audit Working Papers D Appendix D to Part 290 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM Pt...
20 CFR 627.430 - Grant payments.
Code of Federal Regulations, 2011 CFR
2011-04-01
... in accordance with the Cash Management Improvement Act of 1990 (31 U.S.C. 6501, et seq.), Department... provided by the Cash Management Improvement Act (31 U.S.C. 6501, et seq.) and implementing regulations at... working capital, the awarding agency may provide cash on a working capital advance payment basis. Under...
Some Thoughts on the Equal Pay Act and Coaching Salaries.
ERIC Educational Resources Information Center
Boring, Phyllis
This paper discusses the Equal Pay Act, Title VII of the Civil Rights Act of 1964, as it applies to women athletic coaches and physical education teachers. The following points are considered: (1) application of the Equal Pay Act; (2) advantage of voluntary compliance with the Equal Pay Act; (3) factors used to measure "equal work"; (4)…
Salt, Ian P.; Hardie, D. Grahame
2017-01-01
The AMP-activated protein kinase (AMPK) is a key regulator of cellular and whole body energy homeostasis, which acts to restore energy homoeostasis whenever cellular energy charge is depleted. Over the last two decades, it has become apparent that AMPK regulates a number of other cellular functions and has specific roles in cardiovascular tissues, acting to regulate cardiac metabolism and contractile function as well as promoting anti-contractile, anti-inflammatory and anti-atherogenic actions in blood vessels. In this review, we will discuss the role of AMPK in the cardiovascular system, including the molecular basis of mutations in AMPK that alter cardiac physiology and the proposed mechanisms by which AMPK regulates vascular function under physiological and pathophysiological conditions. PMID:28546359
van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels
2015-01-01
This article is a response to Nordén and Norlander’s ‘Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?’[1], in which they assert that ‘at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT’. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander’s interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT. PMID:25767558
Regulatory RNA-assisted genome engineering in microorganisms.
Si, Tong; HamediRad, Mohammad; Zhao, Huimin
2015-12-01
Regulatory RNAs are increasingly recognized and utilized as key modulators of gene expression in diverse organisms. Thanks to their modular and programmable nature, trans-acting regulatory RNAs are especially attractive in genome-scale applications. Here we discuss the recent examples in microbial genome engineering implementing various trans-acting RNA platforms, including sRNA, RNAi, asRNA and CRISRP-Cas. In particular, we focus on how the scalable and multiplex nature of trans-acting RNAs has been used to tackle the challenges in creating genome-wide and combinatorial diversity for functional genomics and metabolic engineering applications. Advances in computational design and context-dependent regulation are also discussed for their contribution in improving fine-tuning capabilities of trans-acting RNAs. Copyright © 2015 Elsevier Ltd. All rights reserved.
18 CFR 367.1830 - Account 183, Preliminary survey and investigation charges.
Code of Federal Regulations, 2010 CFR
2010-04-01
... account must be credited and the appropriate service company property account charged. If the work is... HOLDING COMPANY ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE COMPANIES SUBJECT TO THE PROVISIONS OF THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005...
The Work of Recovery on Two Assertive Community Treatment Teams
Salyers, Michelle P.; Stull, Laura G.; Rollins, Angela L.; Hopper, Kim
2011-01-01
The compatibility of recovery work with the Assertive Community Treatment (ACT) model has been debated; and little is known about how to best measure the work of recovery. Two ACT teams with high and low recovery orientation were identified by expert consensus and compared on a number of dimensions. Using an interpretive, qualitative approach to analyze interview and observation data, teams differed in the extent to which the environment, team structure, staff attitudes, and processes of working with consumers supported principles of recovery orientation. We present a model of recovery work and discuss implications for research and practice. PMID:20839045
[How to promote health competence at work].
Eickholt, Clarissa; Hamacher, W; Lenartz, N
2015-09-01
Health competence is a key concept in occupational health and safety and workplace health promotion for maintaining and enhancing health resources. The effects of governmental or occupational measures to protect or improve health fall short of what is required with regard to the challenges of a changing workplace, e.g., due to the delimitation of work. To secure employability it is becoming more and more important to encourage the personal responsibility of employees. To offer new conclusions on how employers and employees can promote health competence, a survey is required of the research within the fields of health competence and competence development, and of the status quo in enterprises. In this context, a Delphi Study provides an important contribution, with a focus on small and medium-sized enterprises. The development of an extensive understanding of health competence is essential in a work-related context. Beyond knowledge-based health literacy, an action-oriented concept of competence implies the ability and willingness to act in a reasonable and creative manner in complex situations. The development of health competence requires learning embedded in working processes, which challenges competent behaviour. Enabling informal learning is a promising innovative approach and therefore coordinated operational activities are necessary. Ultimately, this is a matter of suitable organisational measures being implemented to meet the health competence needs of an enterprise. Even though the each individual employee bears his or her own health competence, the development potential lies largely within the prevailing working conditions.
Speech-Act and Text-Act Theory: "Theme-ing" in Freshman Composition.
ERIC Educational Resources Information Center
Horner, Winifred B.
In contrast to a speech-act theory that is limited by a simple speaker/hearer relationship, a text-act theory of written language allows for the historical or personal context of a writer and reader, both in the written work itself and in the act of reading. This theory can be applied to theme writing, essay examinations, and revision in the…
Keys to efficient development of useful environmental documents
DOT National Transportation Integrated Search
2007-09-01
National Environmental Policy Act (NEPA) documentsenvironmental impact statements and assessmentsinform agency : decisionmaking and let the public know about anticipated effects of a proposed Federal action. The fundamental purposes and : princ...
Project #OA-FY12-0360, March 5, 2012. The Recovery Funds Working Group of the Recovery Accountability and Transparency Board has initiated a project to capture lessons learned from Recovery Act implementation.
ERIC Educational Resources Information Center
Hager, Ronald M.
2004-01-01
This is a continuation of "Funding of Assistive Technology to Make Work a Reality" (Work and AT), Article # 3 in this Policy and Practice Brief Series. This article will review the provisions of the Americans with Disabilities Act (ADA), with a particular emphasis on how the ADA can be used to ensure that a person with a disability has…
Workplace violence and the meaning of work in healthcare workers: A phenomenological study.
Lamothe, Josianne; Guay, Stephane
2017-01-01
Workplace violence (WPV) has been associated with turnover intentions and reduced job satisfaction, yet the mechanisms behind such associations are still nebulous. Studying the way people make sense of their work in the context of WPV could lead to a better understanding of its consequences. The objective of this exploratory study is to identify key features of meaning of work (MOW) in a group of healthcare workers and explain how these features can change following an act of WPV. Researchers recruited 15 healthcare workers (11 women - 4 men) who had previously been the victim of a serious physical or sexual assault by a patient. A phenomenological approach was used. Two main themes were identified: MOW and relationships with others and MOW and relationship with the self. WPV might have the potential to trigger negative changes in the way some workers perceive their colleagues, their patients and their organisation. It can also interfere with their sense of self-accomplishment; all workers however, were still able to find positive meaning in 'contribution' and 'autonomy'. WPV has the potential to change certain aspects of MOW that could help explain why WPV is associated with lowered job satisfaction, compassion fatigue, and higher turnover. Also, finding meaning through contribution and autonomy can be a form of resilience.
NASA Technical Reports Server (NTRS)
Carr, Daniel; Ellenberger, Rich
2008-01-01
The Human Factors Implementation Team (HFIT) process has been used to verify human factors requirements for NASA International Space Station (ISS) payloads since 2003, resulting in $2.4 million in avoided costs. This cost benefit has been realized by greatly reducing the need to process time-consuming formal waivers (exceptions) for individual requirements violations. The HFIT team, which includes astronauts and their technical staff, acts as the single source for human factors requirements integration of payloads. HFIT has the authority to provide inputs during early design phases, thus eliminating many potential requirements violations in a cost-effective manner. In those instances where it is not economically or technically feasible to meet the precise metric of a given requirement, HFIT can work with the payload engineers to develop common sense solutions and formally document that the resulting payload design does not materially affect the astronaut s ability to operate and interact with the payload. The HFIT process is fully ISO 9000 compliant and works concurrently with NASA s formal systems engineering work flow. Due to its success with payloads, the HFIT process is being adapted and extended to ISS systems hardware. Key aspects of this process are also being considered for NASA's Space Shuttle replacement, the Crew Exploration Vehicle.
29 CFR 825.311 - Intent to return to work.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee and Employer Rights and Obligations Under the Act § 825.311 Intent to return to work. (a) An employer may require an employee on FMLA leave to report periodically on...
29 CFR 825.311 - Intent to return to work.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee and Employer Rights and Obligations Under the Act § 825.311 Intent to return to work. (a) An employer may require an employee on FMLA leave to report periodically on...
29 CFR 825.311 - Intent to return to work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee and Employer Rights and Obligations Under the Act § 825.311 Intent to return to work. (a) An employer may require an employee on FMLA leave to report periodically on...
29 CFR 825.311 - Intent to return to work.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee and Employer Rights and Obligations Under the Act § 825.311 Intent to return to work. (a) An employer may require an employee on FMLA leave to report periodically on...
29 CFR 825.311 - Intent to return to work.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Employee and Employer Rights and Obligations Under the Act § 825.311 Intent to return to work. (a) An employer may require an employee on FMLA leave to report periodically on...
29 CFR 5.5 - Contract provisions and related matters.
Code of Federal Regulations, 2014 CFR
2014-07-01
... and mechanics employed or working upon the site of the work (or under the United States Housing Act of... contractual relationship which may be alleged to exist between the contractor and such laborers and mechanics... Davis-Bacon Act on behalf of laborers or mechanics are considered wages paid to such laborers or...
29 CFR 5.5 - Contract provisions and related matters.
Code of Federal Regulations, 2013 CFR
2013-07-01
... and mechanics employed or working upon the site of the work (or under the United States Housing Act of... contractual relationship which may be alleged to exist between the contractor and such laborers and mechanics... Davis-Bacon Act on behalf of laborers or mechanics are considered wages paid to such laborers or...
29 CFR 5.5 - Contract provisions and related matters.
Code of Federal Regulations, 2012 CFR
2012-07-01
... and mechanics employed or working upon the site of the work (or under the United States Housing Act of... contractual relationship which may be alleged to exist between the contractor and such laborers and mechanics... Davis-Bacon Act on behalf of laborers or mechanics are considered wages paid to such laborers or...
Code of Federal Regulations, 2010 CFR
2010-07-01
... Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION THE EQUAL PAY ACT § 1620.12 Wage... gender than the other for the performance of equal work, the higher rate serves as a wage standard. When a violation of the Act is established, the higher rate paid for equal work is the standard to which...
Assessing Faculty Perspectives about Teaching and Working with Students with Disabilities
ERIC Educational Resources Information Center
Becker, Sandra; Palladino, John
2016-01-01
This study presents a unique assessment of faculty perspectives about teaching and working with students with disabilities against the backdrop of the Individuals with Disabilities Education Act (IDEA) and the Americans with Disabilities Act (ADA). A randomized sample of 127 faculty from a large Midwest comprehensive university completed the…
Code of Federal Regulations, 2013 CFR
2013-01-01
... regarding âliquidated damageâ assessments under the Contract Work Hours and Safety Standards Act, and... authority to take action regarding “liquidated damage” assessments under the Contract Work Hours and Safety Standards Act, and associated labor statutes. (a) Delegation of authority. The Director, Industrial...
Suraj Ahuja; Laurie Perrot
2008-01-01
A key purpose of the National Environmental Policy Act (NEPA) is to âpromote effortswhich will prevent or eliminate damage to the environment and biosphere and stimulate thehealth and welfare of manâ (NEPA, Sec 2). The Council on Environmental Quality states âtheNEPA process is intended to help public officials make decisions that...
ERIC Educational Resources Information Center
Griffen, Sarah
2009-01-01
The American Recovery and Reinvestment Act (ARRA) was signed into law by President Obama on Tuesday, February 17, 2009. It is the broadest and largest funding package in American history. The intent of the statute is to stimulate the economy both through direct spending on a range of programs and to create tax relief. Key to the stimulus is the…
ERIC Educational Resources Information Center
Feldman, Jill; Lucas-McLean, Juanita; Gutmann, Babette; Dynarski, Mark; Betts, Julian
2014-01-01
This report explores implementation of the District of Columbia Opportunity Scholarship Program (OSP) in the first two years after Congress reauthorized it with some changes under the SOAR Act of 2011. Key findings include the following: (1) Just over half of all DC private schools participated in the OSP, with current schools more likely to have…
ERIC Educational Resources Information Center
Feldman, Jill; Lucas-McLean, Juanita; Gutmann, Babette; Dynarski, Mark; Betts, Julian
2014-01-01
This report explores implementation of the District of Columbia Opportunity Scholarship Program (OSP) in the first two years after Congress reauthorized it with some changes under the SOAR Act of 2011. Key findings include the following: (1) Just over half of all DC private schools participated in the OSP, with current schools more likely to have…
McMahon, B T; Domer, T M
1997-01-01
No federal or state lawmaker could have foreseen the nuances involved in the mutual implementations of the Americans with Disabilities Act, the Family and Medical Leave Act, and state workers compensation statutes. These laws are compared and contrasted on a number of key issues. Readers are provided with a decision matrix to guide them and those they represent in the judicious invocation of the most beneficial statute for each issue.
ERIC Educational Resources Information Center
Harrison, Kathy; Taysum, Alison; McNamara, Gerry; O'Hara, Joe
2016-01-01
The Education Act (1998) is a key policy document in Irish education, emphasising the rights, roles and responsibilities of key stakeholders, including parents, teachers and pupils in schools. Since 1998 the Department of Education and Skills (DES) has stressed the need to introduce an increased role for teachers and pupils in decision-making. It…
2012-01-01
Background The Hijra is a distinct type of gender role in South Asia where men act like women. This group of people is socially excluded by the general community, in terms of attainment of an opportunity for a socially productive life. Often this sort of deprivation forces these individuals towards professions like sex trade, in pursuit of sustenance, which as a consequence places them as a key block in the puzzle of an impending generalized HIV epidemic in Pakistan. Methods This study is a qualitative study, which involved 8 in-depth interviews and four focus group discussions, conducted in Rawalpindi and Islamabad (Pakistan) from February to April 2012. The data was audio taped and transcribed. Key themes were identified and built upon. The respondents were contacted through a gate keeper Hijra who was a member of the hijra community. Multiple interview sessions were conducted with each respondent. Results Two key categories of the Hijras were identified as Khusrapan and Zananapan, during the in-depth interview sessions. This initial information paved way for the four focus group discussions. The data was presented using key themes which were identified. The study participants explained their life histories to us which made it obvious that they had been socially excluded at many stages of their lives from performing normal social functions. This lack of occupational and educational opportunities pushed them towards entering the risky business of selling sex. Conclusion The transgender community is socially excluded by the Pakistani society which is leading them to indulge in commercial sex and putting their lives at risk. Prudent measures are needed to form community based organizations managed and led by hijra community and addressing their social exclusion and risky behaviors. PMID:23163979
World Organisation for Animal Health
... Our members Delegates Key texts Basic texts Cooperation agreements Official Acts Resolutions and recommendations Final Reports of ... information: press releases, fact sheets, infographics… Partners Collaboration agreements with regional and world organisations of a public ...
Nursing and the New Deal: we met the challenge.
Pollitt, P; Reese, C N
1997-12-01
The years of the great depression were marked with unemployment and economic ruin for many people. Americans were left feeling helpless and hopeless. After the 1932 presidential election of Franklin Roosevelt, his administration embarked on a course of government known as the New Deal. Many new and innovative programs were established to create jobs and a sense of hope for the public. This article will examine four programs that were of particular interest to nursing: the Federal Emergency Relief Act, the Civil Works Act, the Works Progress Act, and the Social Security Act. Nurses of the time embraced these programs. They participated in their development and implementation and made a difference in the lives of many desperate Americans.
NASA Astrophysics Data System (ADS)
Beechie, T. J.; Snover, A. K.
2014-12-01
Natural resource managers often ask scientists to answer questions that cannot be answered, and scientists commonly offer research that is not useful to managers. To produce management-relevant science, managers and scientists must communicate clearly to identify research that is scientifically doable and will produce results that managers find useful. Scientists might also consider that journals with high impact scores are rarely used by managers, while managers might consider that publishing in top tier journals is important to maintain scientific credentials. We offer examples from climate change and river restoration research, in which agency scientists and managers worked together to identify key management questions that scientists could answer and which could inform management. In our first example, we describe how climate scientists worked with agency staff to develop guidance for selecting appropriate climate change scenarios for use in ecological impacts assessments and Endangered Species Act decision making. Within NOAA Fisheries, agency researchers provide science to guide agency managers, and a key question has been how to adapt river restoration efforts for climate change. Based on discussions with restoration practitioners and agency staff, we developed adaptation guidance that summarizes current science to lead managers to develop climate-resilient restoration plans, as well as maps of population vulnerability for endangered steelhead. From these experiences we have learned that collaborative definition of relevant and producible knowledge requires (1) iterative discussions that go beyond simply asking managers what they need or scientists what they can produce, and (2) candid conversation about the intended applications and potential limitations of the knowledge.
Chmielewski, Danielle; Bove, Liliana L; Lei, Jing; Neville, Ben; Nagpal, Anish
2012-09-01
The Motivation Crowding-out Theory suggests that incentives undermine intrinsic motivation and thus blood donation behavior. While there is strong evidence showing the negative relationship between monetary incentives and blood donation, findings on the effect of nonmonetary incentives are mixed. Set in a voluntary, nonremunerated environment, this study explores aspects of the nonmonetary incentive-blood donation relationship not captured by the crowding-out hypothesis. In-depth interviews were conducted to explore donors' attitudes toward nonmonetary incentives currently used or considered by the Australian Red Cross Blood Service (Blood Service). Transcripts were analyzed using an inductive, thematic approach. Of the nonmonetary incentives examined (i.e., health screening tests, branded tokens, paid time off work, recognition of key milestones, and postdonation refreshments), none were found to crowd out intrinsic motivation, although not all were viewed favorably. Donors who viewed branded tokens negatively considered the cost implications for the Blood Service, while donors who responded positively considered the public benefit of tokens in raising the profile of the Blood Service. Other nonmonetary incentives-paid time off work, postdonation refreshments, and health screening tests-were viewed positively because donors perceived them to be congruent to the effort expended in donating blood. Finally, donors expressed a preference for private over public recognition when acknowledging significant contributions. When operating in a voluntary, nonremunerated environment, blood services should view donors as supply partners rather than customers, only consider nonmonetary incentives that are congruent with the act of donation, and provide private rather than public recognition of key milestones. © 2012 American Association of Blood Banks.
Romney, Wendy; Salbach, Nancy; Parrott, James Scott; Deutsch, Judith E
2018-04-16
Little is known about the process of engaging key stakeholders to select and design a knowledge translation (KT) intervention to increase the use of an outcome measure using audit and feedback. The purpose of this case report was to describe the development of a KT intervention designed with organizational support to increase physical therapists' (PTs) use of a selected outcome measure in an inpatient sub-acute rehabilitation hospital. Eleven PTs who worked at a sub-acute rehabilitation hospital participated. After determining organizational support, a mixed methods barrier assessment including a chart audit, questionnaire, and a focus group with audit and feedback was used to select an outcome measure and design a locally tailored intervention. The intervention was mapped using the Theoretical Domains Framework (TDF). One investigator acted as knowledge broker and co-designed the intervention with clinician and supervisor support. The 4-m walk test was selected through a group discussion facilitated by the knowledge broker. Support from the facility and input from the key stakeholders guided the design of a tailored KT intervention to increase use of gait speed. The intervention design included an interactive educational meeting, with documentation and environmental changes. Input from the clinicians on the educational meeting, documentation changes and placement of tracks, and support from the supervisor were used to design and locally adapt a KT intervention to change assessment practice among PTs in an inpatient sub-acute rehabilitation hospital. Implementation and evaluation of the intervention is underway.
ERIC Educational Resources Information Center
Bureau of National Affairs, Inc., Washington, DC.
This report was prepared because of the growing national interest in the questions of work and family dynamics. It puts together 82 key statistics on work and family issues in four major areas: child care, parental leave, alternative work schedules, and elder care. In addition, a chapter of miscellaneous statistics covers areas such as the…
Community nurse's knowledge, confidence and experience of the Mental Capacity Act in practice.
Marshall, Helen; Sprung, Sally
2016-12-02
The Mental Capacity Act (MCA) is statutory legislation introduced in 2007 to protect and empower people to make decisions for themselves and those who were deemed as unable to make choices would have decisions made on their behalf, often by health professionals. All health professionals must follow the guiding principles of this legislation. Yet a scrutiny report by the House of Lords concluded this legislation was under-used with a lack of knowledge among professionals regarding applying the legislation in practice. A review of the literature also supports these findings. A mixed method study was carried out among adult community nurses to explore if these findings were applicable within a health trust in the North West region. An electronic questionnaire (n=60), focus group (n=7) and a paired interview (n=2) were utilised to collect data regarding community nurse's experience and confidence of using the MCA in practice. Analysis identified key themes: training, knowledge and confidence among staff, working together with the wider multidisciplinary team, empowerment and improving documentation. While findings suggest clear examples of self-appraised confidence and excewllent patient care, there is also scope for development regarding the knowledge and utilisation of the MCA in the clinical practice of community nurses.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maquat, Lynne
2002-12-01
The goal of this meeting was to provide an interactive forum for scientists working on prokaryotic and eukaryotic mRNA decay. A special seminar presented by a leader in the field of mRNA decay in S. cerevisiae focused on what is known and what needs to be determined, not only for yeast but for other organisms. The large attendance (110 participants) reflects the awareness that mRNA decay is a key player in gene regulation in a way that is affected by the many steps that precede mRNA formation. Sessions were held on the following topics: mRNA transport and mRNP; multicomponent eukaryoticmore » nucleases; nonsense-mediated mRNA decay and nonsense-associated altered splicing; Cis-acting sequences/Trans-acting factors of mRNA decay; translational accuracy; multicomponent bacterial nucleases; interplay between mRNA polyadenylation, translation and decay in prokaryotes and prokaryotic organelles; and RNA interference and other RNA mediators of gene expression. In addition to the talks and two poster sessions, there were three round tables: (1) Does translation occur in the nucleus? (2) Differences and similarities in the mechanisms of mRNA decay in different eukaryotes, and (3) RNA surveillance in bacteria?« less
29 CFR 785.4 - Application to Walsh-Healey Public Contracts Act.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Application to Walsh-Healey Public Contracts Act. 785.4... Considerations § 785.4 Application to Walsh-Healey Public Contracts Act. The principles set forth in this part... employees performing work subject to the provisions of the Walsh-Healey Public Contracts Act. [35 FR 15289...
42 CFR 67.105 - Control of data and availability of publications.
Code of Federal Regulations, 2010 CFR
2010-10-01
... PHS Act, section 1142(d) of the Social Security Act, and § 67.104 of this subpart. (b) All publications, reports, papers, statistics, or other materials developed from work supported in whole or in part by contracts under Title IX of the PHS Act or section 1142 of the Social Security Act, if applicable...
42 CFR 67.105 - Control of data and availability of publications.
Code of Federal Regulations, 2011 CFR
2011-10-01
... PHS Act, section 1142(d) of the Social Security Act, and § 67.104 of this subpart. (b) All publications, reports, papers, statistics, or other materials developed from work supported in whole or in part by contracts under Title IX of the PHS Act or section 1142 of the Social Security Act, if applicable...
75 FR 22137 - Agency Forms Undergoing Paperwork Reduction Act Review
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-27
... adolescents prefer to receive health messages and health information (e.g., brochures, videos, podcasts, YouTube.com , etc.). These findings will inform the development of key messages tailored to the target...
Funding Transparency under ESSA. Special Report
ERIC Educational Resources Information Center
Woods, Julie Rowland
2018-01-01
This special report explains the new requirements states have in reporting per-pupil expenditures under the Every Student Succeeds Act. It also provides key considerations for states and information about technical assistance and support.
Yamatani, Hide; Feit, Marvin; Mann, Aaron
2017-01-01
Although the basic paradigm of the U.S. federal drug policy targeting the supply and demand reduction has not changed since its enactment in 1970, there have been seriously undesirable disparate treatments and impacts among various population groups. Although U.S. Congress could not define what is discrimination, it did provide two major criteria for the assessment of discriminatory practices as follows: (a) disparate treatment-basing a key decision on association with any of the five prohibited individual's demographic classifications (race, color, religion, sex, or national origin); and (b) disparate impact-correlation between any of the five prohibited demographic classifications and the key outcomes. In reference to those criteria, this article describes evidence-based indicators of national failure of the Comprehensive Drug Abuse Prevention and Control Act.
WaterSMART-The Colorado River Basin focus-area study
Bruce, Breton W.
2012-01-01
Increasing demand for the limited water resources of the United States continues to put pressure on water-resource agencies to balance the competing needs of ecosystem health with municipal, agricultural, and recreational uses. In 2007, the U.S. Geological Survey (USGS) identified a National Water Census as one of six pivotal future science directions for the USGS in the following decade. The envisioned USGS National Water Census would evaluate large-scale effects of changes in land use and land cover, water use, and climate on water availability, water quality, and human and aquatic ecosystem health. The passage of the SECURE (Science and Engineering to Comprehensively Understand and Responsibly Enhance) Water Act in 2009 was a key step towards implementing the USGS National Water Census. Section 9508 of the Act authorizes a "national water availability and use assessment program" within the USGS (1) to provide a more accurate assessment of the status of the water resources of the United States; and (2) to develop the science for improved forecasts of the availability of water for future economic, energy production, and environmental uses. Initial funding for the USGS to begin working on the National Water Census came with the approval of the U.S. Department of the Interior's WaterSMART (Sustain and Manage America's Resources for Tomorrow) Initiative. The WaterSMART Initiative provides funding to the USGS, Bureau of Reclamation, and U.S. Department of Energy to achieve a sustainable water strategy to meet the Nation's water needs. WaterSMART funding also allowed the USGS to begin the national Water Availability and Use Assessment, as called for under the SECURE Water Act.
Reconsidering Food Reward, Brain Stimulation, and Dopamine: Incentives Act Forward.
Newquist, Gunnar; Gardner, R Allen
2015-01-01
In operant conditioning, rats pressing levers and pigeons pecking keys depend on contingent food reinforcement. Food reward agrees with Skinner's behaviorism, undergraduate textbooks, and folk psychology. However, nearly a century of experimental evidence shows, instead, that food in an operant conditioning chamber acts forward to evoke species-specific feeding behavior rather than backward to reinforce experimenter-defined responses. Furthermore, recent findings in neuroscience show consistently that intracranial stimulation to reward centers and dopamine release, the proposed reward molecule, also act forward to evoke inborn species-specific behavior. These results challenge longstanding views of hedonic learning and must be incorporated into contemporary learning theory.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-28
... ENVIRONMENTAL PROTECTION AGENCY [FRL-9765-4] Clean Air Act Operating Permit Program: Order Responding to Petition for Objection to State Operating Permit for U.S. Steel-- Granite City Works, Granite... Protection Agency (IEPA) for the U.S. Steel--Granite City Works (USGW) facility, located in Granite City...
ERIC Educational Resources Information Center
McConaghy, Cathryn
2006-01-01
This article is a first person's account of working in a rural district affected by drought, economic recession and poor levels of services. It is a facto-fictional narrative describing a typical working day in the life of Peggy, the acting CEO of quality teaching, in what is locally referred to as an NIDA district (where everyone is acting).…
ERIC Educational Resources Information Center
Galloway, Dominique L.
2007-01-01
Problems with implementation of the No Child Left Behind Act (NCLB) can be assessed in light of change management theory. Viewing stakeholders collectively as a corporate entity supports employing change management strategies to make the NCLB work. Examining ways that organizational controls and change management can work together points to…
20 CFR 220.186 - When and how often the Board will conduct a continuing disability review.
Code of Federal Regulations, 2014 CFR
2014-04-01
... Social Security Act. (b) When the Board will conduct a continuing disability review. A continuing... technology raises a disability issue.); (4) The annuitant returns to work and successfully completes a period... returned to work, or that the annuitant is failing to follow the provisions of the Social Security Act, the...
20 CFR 220.186 - When and how often the Board will conduct a continuing disability review.
Code of Federal Regulations, 2012 CFR
2012-04-01
... Social Security Act. (b) When the Board will conduct a continuing disability review. A continuing... technology raises a disability issue.); (4) The annuitant returns to work and successfully completes a period... returned to work, or that the annuitant is failing to follow the provisions of the Social Security Act, the...
20 CFR 220.186 - When and how often the Board will conduct a continuing disability review.
Code of Federal Regulations, 2013 CFR
2013-04-01
... Social Security Act. (b) When the Board will conduct a continuing disability review. A continuing... technology raises a disability issue.); (4) The annuitant returns to work and successfully completes a period... returned to work, or that the annuitant is failing to follow the provisions of the Social Security Act, the...
Code of Federal Regulations, 2013 CFR
2013-10-01
... Safety Standards Act-nursing home care contract supplement. 852.222-70 Section 852.222-70 Federal...—nursing home care contract supplement. As prescribed in 822.305, for nursing home care requirements, insert the following clause: Contract Work Hours and Safety Standards Act—Nursing Home Care Contract...
Code of Federal Regulations, 2012 CFR
2012-10-01
... Safety Standards Act-nursing home care contract supplement. 852.222-70 Section 852.222-70 Federal...—nursing home care contract supplement. As prescribed in 822.305, for nursing home care requirements, insert the following clause: Contract Work Hours and Safety Standards Act—Nursing Home Care Contract...
Code of Federal Regulations, 2010 CFR
2010-10-01
... Safety Standards Act-nursing home care contract supplement. 852.222-70 Section 852.222-70 Federal...—nursing home care contract supplement. As prescribed in 822.305, for nursing home care requirements, insert the following clause: Contract Work Hours and Safety Standards Act—Nursing Home Care Contract...
Code of Federal Regulations, 2011 CFR
2011-10-01
... Safety Standards Act-nursing home care contract supplement. 852.222-70 Section 852.222-70 Federal...—nursing home care contract supplement. As prescribed in 822.305, for nursing home care requirements, insert the following clause: Contract Work Hours and Safety Standards Act—Nursing Home Care Contract...
Code of Federal Regulations, 2014 CFR
2014-10-01
... Safety Standards Act-nursing home care contract supplement. 852.222-70 Section 852.222-70 Federal...—nursing home care contract supplement. As prescribed in 822.305, for nursing home care requirements, insert the following clause: Contract Work Hours and Safety Standards Act—Nursing Home Care Contract...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-05
... housing and Section 8 assisted housing programs made by the Quality Housing and Work Responsibility (QHWRA... occupancy requirements for the public housing and Section 8 assisted housing programs made by the Quality Housing and Work Responsibility (QHWRA) Act 1998 (Title V of the FY 1999 HUD appropriations Act, Pub. L...
Flexible Workplace Policies: Lessons from the Federal Alternative Work Schedules Act
ERIC Educational Resources Information Center
Liechty, Janet M.; Anderson, Elaine A.
2007-01-01
This case study uses a feminist framework to examine the 7-year process by which the Federal Alternative Work Schedules Act (1978-1985) became law and the reasons for reenergized implementation in the 1990s. We analyze the legislative discourse for rationale in support of and opposition to this policy, connect findings to current flexible work…
The apelin peptides as putative targets in cardiovascular drug discovery and development.
Charles, Cj
2008-01-01
Apelin is a recently isolated peptide that appears to act as an endogenous ligand for the previously orphaned G-protein-coupled receptor APJ. A number of studies have reported cardiovascular actions of apelin, including changes in the blood pressure and potent inotropic actions. Furthermore, perturbations of both apelin and APJ within the myocardial tissue and circulating levels of the peptide have been reported in a number of cardiovascular disease states. Taken together, these studies suggest a role for apelin in the pressure/volume homeostasis and in the pathophysiology of cardiovascular diseases. However, findings in the literature to date are, at times, disparate. This review highlights key areas where further work is required to clarify the role of apelin/APJ in both normal physiology and pathophysiology. Nonetheless, preliminary evidence suggests that the manipulation of this receptor/ligand peptide system may be a target for drug development, thereby offering a therapeutic benefit in cardiovascular diseases.
Mother Nature versus human nature: public compliance with evacuation and quarantine.
Manuell, Mary-Elise; Cukor, Jeffrey
2011-04-01
Effectively controlling the spread of contagious illnesses has become a critical focus of disaster planning. It is likely that quarantine will be a key part of the overall public health strategy utilised during a pandemic, an act of bioterrorism or other emergencies involving contagious agents. While the United States lacks recent experience of large-scale quarantines, it has considerable accumulated experience of large-scale evacuations. Risk perception, life circumstance, work-related issues, and the opinions of influential family, friends and credible public spokespersons all play a role in determining compliance with an evacuation order. Although the comparison is not reported elsewhere to our knowledge, this review of the principal factors affecting compliance with evacuations demonstrates many similarities with those likely to occur during a quarantine. Accurate identification and understanding of barriers to compliance allows for improved planning to protect the public more effectively. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.
APMP comparison on luminous flux units (APMP.PR-K4)
NASA Astrophysics Data System (ADS)
Liu, H.; Lin, Y. D.; Yang, C. Z.; Yu, J.
2018-01-01
During the 18th APMP meeting in 2004, TCPR agreed that the luminous flux should be one of the several regional comparisons to be conducted in the field of photometry and radiometry, and the project was named as APMP.PR-K4. Nine laboratories took part in this comparison. A group of LF 200W lamps (no less than three) was used as transfer artifacts by each participant. The National Institute of Metrology (NIM, China) acted as the pilot laboratory. Presented in this report are the detailed procedures and results of the work. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Signaling, Regulation, and Specificity of the Type II p21-activated Kinases.
Ha, Byung Hak; Morse, Elizabeth M; Turk, Benjamin E; Boggon, Titus J
2015-05-22
The p21-activated kinases (PAKs) are a family of six serine/threonine kinases that act as key effectors of RHO family GTPases in mammalian cells. PAKs are subdivided into two groups: type I PAKs (PAK1, PAK2, and PAK3) and type II PAKs (PAK4, PAK5, and PAK6). Although these groups are involved in common signaling pathways, recent work indicates that the two groups have distinct modes of regulation and have both unique and common substrates. Here, we review recent insights into the molecular level details that govern regulation of type II PAK signaling. We also consider mechanisms by which signal transduction is regulated at the level of substrate specificity. Finally, we discuss the implications of these studies for clinical targeting of these kinases. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.