Sample records for action affecting export

  1. 76 FR 11756 - Action Affecting Export Privileges; Ali Amirnazmi; Order Denying Export Privileges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Ali Amirnazmi; Order Denying Export Privileges In the Matter of: Ali Amirnazmi, Register 63302-066, FCI... release and forfeit $81,277.37. Section 766.25 of the Export Administration Regulations (``EAR'' or...

  2. 75 FR 32741 - Action Affecting Export Privileges; Shu Quan-Sheng

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Shu... Regulations; B. Take any action that facilitates the acquisition or attempted acquisition by the Denied Person.... Take any action to acquire from or to facilitate the acquisition or attempted acquisition from the...

  3. 75 FR 8917 - Action Affecting Export Privileges; Afshin Rezaei

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Afshin... any item subject to the Regulations; B. Take any action that facilitates the acquisition or attempted..., possession or control; C. Take any action to acquire from or to facilitate the acquisition or attempted...

  4. 75 FR 11112 - Action Affecting Export Privileges; Robert Kraaipoel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Robert.... Take any action that facilitates the acquisition or attempted acquisition by the Denied Person of the... any action to acquire from or to facilitate the acquisition or attempted acquisition from the Denied...

  5. 75 FR 16735 - Action Affecting Export Privileges; Bob Rahimzadeh

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security [09-BIS-005] Action Affecting Export... obtained for the transaction described herein. Rahimzadeh took this action after having been asked by Parto... action that facilitates the acquisition or attempted acquisition by the Denied Person of the ownership...

  6. 75 FR 32742 - Action Affecting Export Privileges; Joseph Piquet

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Joseph... on behalf of the Denied Person any item subject to the Regulations; B. Take any action that... or attempts to acquire such ownership, possession or control; C. Take any action to acquire from or...

  7. 76 FR 39844 - Action Affecting Export Privileges; ERIC COHEN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; ERIC... continuing through and including on or about June 6, 2005, Cohen engaged in a transaction or took actions..., permission, or privilege granted, or to be granted, to Cohen. Fourth, Cohen agrees not to take any action or...

  8. 75 FR 842 - Action Affecting Export Privileges: Hailin Lin

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-06

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges: Hailin... Regulations. Charges 112-12415: CFR 764.2(h)--Taking Action With Intent To Evade the Regulations In connection... through on or about September 30, 2004, Lin took actions with intent to evade the provisions of the...

  9. 76 FR 13127 - Action Affecting Export Privileges; Amy Farrow

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Action Affecting Export Privileges; Amy... reexport to or on behalf of the Denied Person any item subject to the Regulations; B. Take any action that... Denied Person acquires or attempts to acquire such ownership, possession or control; C. Take any action...

  10. 75 FR 337 - Action Affecting Export Privileges: Ning Wen

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security [07-BIS-02] Action Affecting Export.... Charges 112-124: 15 CFR 764.2(h)--Taking Action With Intent To Evade the Regulations In connection with... or about September 30, 2004, Wen took actions with intent to evade the provisions of the Regulations...

  11. 78 FR 11645 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2013-0115] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the United States. ACTION...-Im Bank approved insurance claims. Affected Public: This form affects entities involved in the export...

  12. 76 FR 29241 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-0035] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments... under Export Import Bank's credit insurance programs. Affected Public: This form affects entities...

  13. 76 FR 7846 - Agency Information Collection: Emergency Submission for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... Export Import Bank's credit insurance programs. Affected Public: This form affects entities involved in... EXPORT IMPORT BANK OF THE UNITED STATES [OMB Control No: 3048-0024 EIB 92-79] Agency Information Collection: Emergency Submission for OMB Review AGENCY: Export Import Bank of the United States. ACTION...

  14. 78 FR 55254 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... EXPORT IMPORT BANK [Public Notice 2013-6005] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB review and comments... applicant and transaction for Ex-Im Bank assistance under its programs. Affected Public: This form affects...

  15. 77 FR 58989 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... EXPORT-IMPORT BANK [Public Notice 2012-0505] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and... Bank under its insurance, guarantee, and direct loan programs. Affected Public: This form affects...

  16. 75 FR 74717 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2010-0060] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB review and comments... Import Bank's credit insurance programs. Affected Public: This form affects entities involved in the...

  17. 75 FR 57465 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2010-0037] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments...-Import Bank's credit insurance programs. Affected Public: This form affects entities involved in the...

  18. 75 FR 8353 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... EXPORT[dash]IMPORT BANK OF THE U.S. [Public Notice 145] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... affects entities involved in the export of U.S. goods and services. Annual Number of Respondents: 84...

  19. 75 FR 11113 - Action Affecting Export Privileges; Aviation Services International, B.V.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... the United States on behalf of Iranian customers and give U.S. manufacturers false information regarding the ultimate destination, end user, and end use of the items, thereby causing false export control...

  20. 75 FR 16732 - Action Affecting Export Privileges; Aqua-Loop Cooling Towers, Co.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... Regulations by facilitating or coordinating the export of approximately 174 rolls of hog hair filter media... about September 28, 2004, Aqua-Loop ordered or financed approximately 174 rolls of hog hair filter media... coordinating the export of approximately 185 rolls of hog hair filter media, part number HHB6O 130 and valued...

  1. 76 FR 22865 - Action Affecting Export Privileges; Orion Air, S.L. and Syrian Pearl Airlines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... to the EAR that has been or will be exported from the United States. For purposes of this paragraph....24 of the Export Administration Regulations, 15 CFR parts 730-774 (2011) (``EAR'' or the... violation of the EAR. I. Procedural History On May 7, 2009, then-Acting Assistant Secretary of Commerce for...

  2. 77 FR 11533 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2012-0082] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments... the application and transaction are eligible for Ex-Im Bank and SBA assistance. Affected Public: This...

  3. 75 FR 56052 - Action Affecting Export Privileges; Mahan Airways and Gatewick LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    .... On August 13, 2010, BIS, through its Office of Export Enforcement (``OEE''), filed a written request.... The TDO and BIS's Request for Renewal OEE's request for renewal is based upon the facts underlying the... the aircraft. OEE's evidence indicates that Aircraft 1-3 remain in Mahan Airways' possession, control...

  4. 76 FR 19033 - Action Affecting Export Privileges; Credit International Trading Co. Ltd; In the Matter of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... Wang's conviction. The 10-year denial period will end on May 2, 2015. Accordingly, it is hereby Ordered... Denying Export Privileges of Ruo Ling Wang Applicable to Related Person Credit International Trading... individual Ruo Ling Wang (``Wang'') on April 18, 2006 (71 Fed. Reg. 23897, April 25, 2006) applicable to...

  5. 75 FR 13079 - Action Affecting Export Privileges; MAHAN AIRWAYS; Mahan Airways, Mahan Tower, No. 21, Azadegan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... AIRWAYS; Mahan Airways, Mahan Tower, No. 21, Azadegan St., M.A. Jenah Exp. Way, Tehran, Iran, Respondent... prohibited by the EAR by knowingly re-exporting to Iran three U.S.-origin aircraft, specifically Boeing 747s... (``Aircraft 4-6'') to Iran. As more fully discussed in the September 17, 2008 TDO Renewal Order, evidence...

  6. 77 FR 25235 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... action may also affect certain entities through pre-existing import certification and export notification..., including provisions for developing test data. B. What is the agency's authority for taking this action...) consent orders). Tests recommended by EPA to provide sufficient information to evaluate the chemical...

  7. 75 FR 57169 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... action may also affect certain entities through pre-existing import certification and export notification... provisions for developing test data. B. What is the Agency's Authority for Taking this Action? Section 5(a)(2...., SNURs without TSCA section 5(e) consent orders). Toxicity concerns. Tests recommended by EPA to provide...

  8. 75 FR 10462 - Action Affecting Export Privileges; Mohamad M. Elkateb; In the Matter of: Mohamad M. Elkateb...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    .... \\2\\ 50 U.S.C. app. 2401-2420 (2000). Since August 21, 2001, the Act has been in lapse and the... scheme to purchase U.S.-origin lab equipment for a customer in Syria from a foreign distributor of the U...

  9. 75 FR 80456 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... . SUPPLEMENTARY INFORMATION: Title III of the Export Trading Company Act of 1982 (15 U.S.C. Sections 4001-21... government antitrust actions and from private treble damage antitrust actions for the export conduct... of technology rights. 2. ARC seeks certification to exchange information with individual Suppliers on...

  10. 21 CFR 1309.44 - Suspension of registration pending final order.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications... Administration all of the particular chemical or chemicals in his or her possession that were obtained under the..., which are affected by the revocation or suspension; or (2) Place all of such chemicals under seal as...

  11. 21 CFR 1309.44 - Suspension of registration pending final order.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications... Administration all of the particular chemical or chemicals in his or her possession that were obtained under the..., which are affected by the revocation or suspension; or (2) Place all of such chemicals under seal as...

  12. 21 CFR 1309.44 - Suspension of registration pending final order.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications... Administration all of the particular chemical or chemicals in his or her possession that were obtained under the..., which are affected by the revocation or suspension; or (2) Place all of such chemicals under seal as...

  13. 21 CFR 1309.44 - Suspension of registration pending final order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications... Administration all of the particular chemical or chemicals in his or her possession that were obtained under the..., which are affected by the revocation or suspension; or (2) Place all of such chemicals under seal as...

  14. 77 FR 48858 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... affect certain entities through pre-existing import certification and export notification rules under... developing test data. B. What is the agency's authority for taking this action? Section 5(a)(2) of TSCA (15 U....e., SNURs without TSCA section 5(e) consent orders). Tests recommended by EPA to provide sufficient...

  15. 78 FR 45969 - Trade Barriers That U.S. Small and Medium-Sized Enterprises Perceive as Affecting Exports to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 332-541] Trade Barriers That U.S. Small and... Investigation and Scheduling of Hearing AGENCY: United States International Trade Commission. ACTION... 332(g) of the Tariff Act of 1930 (19 U.S.C. 1332(g)), the U.S. International Trade Commission...

  16. 75 FR 71075 - Action Affecting Export Privileges; Anvik Technologies Sdn. Bhd., a/k/a Anvik Technologies; Babak...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... office space'' leased by Respondents from a company called Servcorp. See note 4. infra. It is BIS's understanding that other persons also rent ``virtual office space'' at this address. The only current users at... ship those items to Iran through third countries. Respondents use the leased virtual office space in...

  17. 76 FR 12318 - Action Affecting Export Privileges; Mahan Airways, Gatewick LLC; Pejman Mahmood Kosarayanifard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Enforcement (``OEE''), filed a written request for renewal of the TDO against Mahan Airways and Gatewick.... The TDO and BIS's Request for Renewal OEE's request for renewal is based upon the facts underlying the... evidence obtained by OEE indicates that Aircraft 1-3 remain in Mahan Airways' possession, control, and...

  18. 75 FR 25202 - Action Affecting Export Privileges; Orion Air, S.L. and Syrian Pearl Airlines; Order Renewing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... Administration Regulations, 15 CFR parts 730-774 (2009) (``EAR'' or the ``Regulations''), I hereby grant the...'') is necessary in the public interest to prevent an imminent violation of the EAR. I. Procedural... EAR, the sole issue to be considered in determining whether to continue a TDO is whether the TDO...

  19. 75 FR 63802 - Action Affecting Export Privileges; Parto Abgardan Cooling Towers Co.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... to prevent evasion, certain types of orders under [Part 766] may be made applicable not only to the... order to prevent evasion of that denial order, the Assistant Secretary shall issue or amend the order... the Denial Order is justified in order to prevent evasion of that Order. I find that BIS has presented...

  20. 75 FR 32740 - Action Affecting Export Privileges; Aaron Robert Henderson and Valhalla Tactical Supply

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... in the conduct of trade or business in order to prevent evasion of a denial order. Because Henderson... is necessary to avoid evasion of the denial order against Henderson. As provided in Section 766.23 of... entity related to Henderson would be necessary to prevent evasion of a denial order imposed against...

  1. 77 FR 37871 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application 12-00005] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review from Colombia Rice Export Quota, Inc. SUMMARY: The Export Trading Company Affairs (``ETCA'') unit, Office of...

  2. 77 FR 73627 - 2012 LNG Export Study

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... DEPARTMENT OF ENERGY 2012 LNG Export Study AGENCY: Office of Fossil Energy, Department of Energy. ACTION: Notice of availability of 2012 LNG Export Study and request for comments. Freeport LNG Expansion... liquefied natural gas (LNG) export cumulative impact study (LNG Export Study) in the above- referenced...

  3. 15 CFR 720.3 - Final decision on administrative action denying export privileges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

  4. 15 CFR 720.3 - Final decision on administrative action denying export privileges.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

  5. 75 FR 11118 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-4A005] Export Trade Certificate of Review ACTION: Notice of Application ( 99-4A005) to Amend the Export Trade Certificate of Review Issued to California Almond Export Association, LLC, Application no. 99-00005. SUMMARY: The Export...

  6. 75 FR 51980 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-21A12] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to Northwest... amended Export Trade Certificate of Review to Northwest Fruit Exporters on August 18, 2010. The...

  7. 77 FR 72324 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-17A18] Export Trade Certificate of Review ACTION: Notice of Application to Amend the Export Trade Certificate of Review Issued to... to amend an Export [[Page 72325

  8. 75 FR 66728 - Action Affecting Export Privileges; Orion Air, S.L. and Syrian Pearl Airlines: Orion Air, S.L...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ... Administration Regulations, 15 CFR Parts 730-774 (2010) (``EAR'' or the ``Regulations''), I hereby grant the...'') is necessary in the public interest to prevent an imminent violation of the EAR. I. Procedural...)(3) of the EAR, the sole issue to be considered in determining whether to continue a TDO is whether...

  9. 75 FR 56504 - Action Affecting Export Privileges; Rigel Optics, Inc. and Donald Wayne Hatch; Order Denying...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... responsibility, affiliation, or other connection in the conduct of trade or business in order to prevent evasion... believes that naming Hatch as a related person to Rigel Optics is necessary to avoid evasion of the denial... necessary to prevent evasion of a denial order imposed against Rigel Optics. In providing such notice, I...

  10. 75 FR 63801 - Action Affecting Export Privileges; Joseph Piquet and Related Person Alphatronx, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... evasion, certain types of orders under this part may be made applicable not only to the respondent, but... it is necessary to add this entity to the Piquet Denial Order in order to avoid evasion of that Order... would be necessary to prevent evasion of a denial order imposed against Piquet. In providing such notice...

  11. 75 FR 32743 - Action Affecting Export Privileges; Green Supply, Inc.; Robert Leland Green and William Robert...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... responsibility, affiliation, or other connection in the conduct of trade or business in order to prevent evasion... to GSI is necessary to avoid evasion of the denial order against GSI. As provided in Section 766.23... believes naming them as persons related to GSI would be necessary to prevent evasion of a denial order...

  12. 76 FR 66693 - President's Export Council: Meeting of the President's Export Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    .... ACTION: Notice of an open meeting. SUMMARY: The President's Export Council will hold a meeting to discuss.... exports, jobs, and growth. DATES: November 16, 2011 at 9:30 a.m. (ET) ADDRESSES: The President's Export... on December 20, 1973 to advise the President on matters relating to U.S. export trade and report to...

  13. 78 FR 1837 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-23A12] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Northwest Fruit Exporters, Application No. 84-23A12. SUMMARY: The U.S. Department of Commerce issued an amended Export Trade...

  14. 76 FR 55010 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-22A12] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Northwest Fruit Exporters, Application no. 84-22A12. SUMMARY: The U.S. Department of Commerce issued an amended Export Trade...

  15. 78 FR 53727 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-24A12] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Northwest Fruit Exporters, Application No. 84-24A12. SUMMARY: The U.S. Department of Commerce issued an amended Export Trade...

  16. 15 CFR 766.25 - Administrative action denying export privileges.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

  17. 15 CFR 766.25 - Administrative action denying export privileges.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

  18. 15 CFR 766.25 - Administrative action denying export privileges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

  19. 15 CFR 766.25 - Administrative action denying export privileges.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

  20. 15 CFR 766.25 - Administrative action denying export privileges.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

  1. 75 FR 44761 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application 10-00004] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review From Canned Wild Salmon Export Council, LLC (``CWSEC''). SUMMARY: The Office of Competition and Economic Analysis...

  2. 77 FR 37385 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application 12-00004] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review Colombia Poultry Export Quota, Inc. (COLOM-PEQ). SUMMARY: The Office of Competition and Economic Analysis, International...

  3. 75 FR 8040 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application 10-00001] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review from Alaska Longline Cod Commission (``ALCC'') SUMMARY: The Export Trading Company Affairs (``ETCA'') unit, Office of...

  4. 78 FR 78818 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 13-00001] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Emporia Trading LLC, Application No. 13-00001. SUMMARY: The U.S. Department of Commerce issued an Export Trade...

  5. 78 FR 36747 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 89-4A018] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  6. 78 FR 32622 - District Export Council Nomination Opportunity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... Administration District Export Council Nomination Opportunity AGENCY: International Trade Administration, Department of Commerce. ACTION: Notice of Opportunity for Appointment to serve as a District Export Council... consideration for appointment by the Secretary of Commerce to serve as members of one of the 59 District Export...

  7. 77 FR 2036 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-13

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-10A001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Aerospace... an amended Export Trade Certificate of Review to Aerospace Industries of America on September 27...

  8. 78 FR 62585 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 89-5A018] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  9. 76 FR 15294 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-00005] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to ARC Industries... issued an Export Trade Certificate of Review to ARC Industries Ltd. (``ARC''). This notice summarizes the...

  10. 78 FR 30273 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-24A12] Export Trade Certificate of Review ACTION: Notice of Application to Amend the Export Trade Certificate of Review Issued to... application to amend an Export Trade Certificate of Review (``Certificate''). This notice summarizes the...

  11. 76 FR 55010 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 11-00001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to the Latin.... Department of Commerce issued an Export Trade Certificate of Review to the Latin American Multichannel...

  12. 77 FR 58809 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00005] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Colombia Rice Export Quota, Inc. (``COL-RICE'') (Application 12-00005). SUMMARY: On August 28, 2012, the U.S...

  13. 76 FR 10885 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 11-00001] Export Trade Certificate of Review ACTION: Notice of Application ( 11-00001) for an Export Trade Certificate of Review for... an application for an Export Trade Certificate of Review (``Certificate'') on February 3, 2011. This...

  14. 77 FR 61744 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-23A12] Export Trade Certificate of Review ACTION: Notice of application to amend the Export Trade Certificate of Review issued to... application to amend an Export Trade Certificate of Review (``Certificate''). This notice summarizes the...

  15. 78 FR 16819 - Export Sales Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... CFR Part 20 Export Sales Reporting Requirements AGENCY: Office of the Secretary, USDA. ACTION... muscle cuts/whether or not boxed) and distillers dried grain (DDG) be added to the Export Sales Reporting... document provides for an additional comment period regarding mandatory export sales reporting for DDG...

  16. 77 FR 41970 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Panama Poultry Export Quota, Inc. (``PAN-PEQ'') (Application 12-00001). SUMMARY: On June 25, 2012, the U.S. Department...

  17. 75 FR 25207 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 88-12A16] Export Trade Certificate of Review ACTION: Notice of Application ( 88-12A16) to Amend the Export Trade Certificate of Review Issued to Wood Machinery Manufacturers of America, Application no. 88-00016. SUMMARY: Export...

  18. 78 FR 25060 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-11A001] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to Aerospace... issued an amended Export Trade Certificate of Review to Aerospace Industries Association of America on...

  19. 78 FR 31517 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-5A002] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to California Almond Export Association, LLC (``CAEA'') (Application 99-5A002). SUMMARY: The U.S. Department of...

  20. 76 FR 23788 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 88-13A16] Export Trade Certificate of Review ACTION: Notice of application (88-13A16) to amend the Export Trade Certificate of Review..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  1. 75 FR 31423 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-21A12] Export Trade Certificate of Review ACTION: Notice of Application ( 84-21A12) To Amend an Export Trade Certificate of Review... application to amend an Export Trade Certificate of Review (``Certificate''). This notice summarizes the...

  2. 76 FR 81914 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 97-11A03] Export Trade Certificate of Review ACTION: Notice of application (97-11A03) to amend the Export Trade Certificate of Review..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  3. 78 FR 36747 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-6A002] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to California Almond Export Association, Application no. 99-6A002. SUMMARY: The Office of Competition and...

  4. 76 FR 27994 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-22A12] Export Trade Certificate of Review ACTION: Notice of Application (84-22A12) to Amend the Export Trade Certificate of Review... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  5. 78 FR 13861 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-17A18] Export Trade Certificate of Review ACTION: Notice of Issuance of an Amended Export Trade Certificate of Review to U.S..., Office of Competition and Economic Analysis (OCEA), has issued an amended Export Trade Certificate of...

  6. 77 FR 59591 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00002] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to SunWest Foods... Export Trade Certificate of Review to SunWest Foods, Inc (``SunWest).'' This notice summarizes the...

  7. 77 FR 61744 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-3A001] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Alaska Longline... Commerce issued an amended Export Trade Certificate of Review to the Alaska Longline Cod Commission (``ALCC...

  8. 76 FR 39846 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-1A001] Export Trade Certificate of Review ACTION: Notice of application (10-1A001) to Amend the export trade certificate of review..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  9. 77 FR 12562 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-2A001] Export Trade Certificate of Review ACTION: Notice of Application (10-2A001) to Amend the Export Trade Certificate of Review..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  10. 76 FR 63608 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-10A01] Export Trade Certificate of Review ACTION: Notice of Application (92-10A01) to amend the Export Trade Certificate of Review... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  11. 76 FR 63608 - Export Trade Certificate Of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-1A001] Export Trade Certificate Of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Alaska Longline... Export Trade Certificate of Review Alaska Longline Cod Commission (``ALCC'') on September 21, 2011. This...

  12. 78 FR 58285 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-6A002] Export Trade Certificate of Review ACTION: Notice of issuance of an amended Export Trade Certificate of Review to California Almond Export Association, LLC (``CAEA'') (Application 99-6A002). SUMMARY: The U.S. Department of...

  13. 75 FR 51439 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 88-12A-16] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to Wood... Commerce issued an amended Export Trade Certificate of Review to Wood Machinery Manufacturers of America on...

  14. 15 CFR 736.2 - General prohibitions and determination of applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., Administrative Enforcement Proceedings. These orders prohibit many actions in addition to direct exports by the... knowledge that a violation has occurred or is about to occur (Knowledge Violation to Occur). You may not... to be exported with knowledge that a violation of the Export Administration Regulations, the Export...

  15. 76 FR 64944 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-076] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... between a U.S. exporter, Ex-Im Bank, and a foreign export credit agency; the information collected...

  16. 77 FR 284 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-0080] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... between a U.S. exporter, Ex-Im Bank, and a foreign export credit agency; the information collected...

  17. 78 FR 13861 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-5A002] Export Trade Certificate of Review ACTION: Notice of Application (99-5A002) to amend the Export Trade Certificate of Review Issued to California Almond Export Association, Application No. 99-5A002. SUMMARY: The Office of...

  18. 75 FR 65449 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 94-4A007] Export Trade Certificate of Review ACTION: Notice of issuance of an amended export trade certificate of review to Florida Citrus Exports L.C. (``FCE'') (Application 94-4A007). SUMMARY: The U.S. Department of Commerce issued an...

  19. 75 FR 28235 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-16A18] Export Trade Certificate of Review ACTION: Notice of Application ( 85-16A18) to Amend the Export Trade Certificate of Review Issued to U.S. Shippers Association, Application No. 85-00018. SUMMARY: The Export Trading Company...

  20. 77 FR 18791 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 97-11A003] Export Trade Certificate of Review ACTION: Notice of Issuance of Application No. 97-11A003 of an Amended Export Trade... Commerce issued an amended Export Trade Certificate of Review to the Association for the Administration of...

  1. 75 FR 50747 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-16A18] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to U.S... Export Trade Certificate of Review to U.S. Shippers Association (``USSA'') on August 9, 2010. The...

  2. 76 FR 47148 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 88-13A16] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Wood [[Page 47149... Commerce issued an amended Export Trade Certificate of Review to Wood Machinery Manufacturers of America on...

  3. 75 FR 14567 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 97-10A03] Export Trade Certificate of Review ACTION: Notice of issuance ( 97-10A03) of an amended Export Trade Certificate of Review... Commerce issued an amended Export Trade Certificate of Review to the Association for the Administration of...

  4. 75 FR 35441 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-4A005] Export Trade Certificate of Review ACTION: Notice of Issuance ( 99-4A005) of an Amended Export Trade Certificate of Review to the California Almond Export Association, LLC. SUMMARY: The U.S. Department of Commerce issued an...

  5. 77 FR 28853 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-2A001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Alaska Longline... Export Trade Certificate of Review Alaska Longline Cod Commission (``ALCC'') on May 7, 2012. This is the...

  6. 75 FR 44762 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 94-4A007] Export Trade Certificate of Review ACTION: Notice of Application (94-4A007) To Amend the Export Trade Certificate of Review Issued to Florida Citrus Exports, L.C. (``FCE''), Application No. 94-00007. SUMMARY: The Office of...

  7. 75 FR 35441 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-00002] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to EFS International Corporation/DBA: EFS Global Trade and Export Sales (Application 10-00002). SUMMARY: On May 27, 2010, the U.S...

  8. 77 FR 35679 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2012-0136] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for... Financial Institution of Medium Term Export Credit Insurance Policy. SUMMARY: The Export-Import Bank of the...

  9. 78 FR 54623 - Effects of Foreign Policy-Based Export Controls

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... Foreign Policy-Based Export Controls AGENCY: Bureau of Industry and Security, Commerce. ACTION: Request... export controls in the Export Administration Regulations. BIS is requesting public comments to conduct... with industry on the effect of such controls and to report the results of the consultations to Congress...

  10. 76 FR 12371 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Controlled Substances/Export Controlled Substances for Re-Export--DEA Forms 161 and 161r ACTION: 60-Day... Administration (DEA), will submit the following information collection request to the Office of Management and...: Application for Permit to Export Controlled Substances/Export Controlled Substances for Reexport--DEA Forms...

  11. 77 FR 41885 - Privacy Act of 1974: Implementation of Exemptions; Export-Import Bank of the United States Office...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... EXPORT-IMPORT BANK OF THE UNITED STATES 12 CFR Part 404 [EXIM-OIG-2012-0010] RIN 3048-AA02 Privacy Act of 1974: Implementation of Exemptions; Export-Import Bank of the United States Office of Inspector..., Export-Import Bank of the United States. ACTION: Final rule. SUMMARY: The Export-Import Bank of the...

  12. 15 CFR 720.2 - Initiation of administrative action denying export privileges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

  13. 15 CFR 720.2 - Initiation of administrative action denying export privileges.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

  14. 75 FR 44760 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-00003] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Saintilien... July 21, 2010, the Department of Commerce issued an [[Page 44761

  15. 76 FR 34212 - Lake Charles Exports, LLC; Application for Long-Term Authorization To Export Liquefied Natural Gas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-13

    ... facilities that would permit gas to be received by pipeline at the terminal and liquefied for subsequent... the LNG exports in the requested authorization will not have a material impact on domestic natural gas...-Term Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice...

  16. 76 FR 29991 - Live Goats and Swine for Export; Removal of Certain Testing Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... testing of goats and breeding swine intended for export to countries that do not require such tests. This action will facilitate the exportation of goats and breeding swine by eliminating the need to conduct pre... prior to export. Some countries do not require that goats and breeding swine be tested for tuberculosis...

  17. 75 FR 53014 - Notice and Modification of Action: Canada-Compliance with Softwood Lumber Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Agreement (SLA), Canada agreed to impose export measures on Canadian exports of softwood lumber products to... until the total of the amounts collected under the U.S. import duty and the Canadian charge on exports... Canadian charge on exports is equal to CDN $68 million. The understanding also provides for the United...

  18. 27 CFR 28.37 - Action by appropriate TTB officer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Destruction of Liquors After Receipt in A Foreign-Trade Zone § 28.37 Action by appropriate TTB officer. The... transported to and deposited in a foreign-trade zone in good faith for the purpose of exportation or storage pending exportation, and that the liquors, after deposit in the zone, have become unmerchantable or unfit...

  19. 27 CFR 28.37 - Action by appropriate TTB officer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Destruction of Liquors After Receipt in A Foreign-Trade Zone § 28.37 Action by appropriate TTB officer. The... transported to and deposited in a foreign-trade zone in good faith for the purpose of exportation or storage pending exportation, and that the liquors, after deposit in the zone, have become unmerchantable or unfit...

  20. 27 CFR 28.37 - Action by appropriate TTB officer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Destruction of Liquors After Receipt in A Foreign-Trade Zone § 28.37 Action by appropriate TTB officer. The... transported to and deposited in a foreign-trade zone in good faith for the purpose of exportation or storage pending exportation, and that the liquors, after deposit in the zone, have become unmerchantable or unfit...

  1. 27 CFR 28.37 - Action by appropriate TTB officer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Destruction of Liquors After Receipt in A Foreign-Trade Zone § 28.37 Action by appropriate TTB officer. The... transported to and deposited in a foreign-trade zone in good faith for the purpose of exportation or storage pending exportation, and that the liquors, after deposit in the zone, have become unmerchantable or unfit...

  2. 27 CFR 28.37 - Action by appropriate TTB officer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Destruction of Liquors After Receipt in A Foreign-Trade Zone § 28.37 Action by appropriate TTB officer. The... transported to and deposited in a foreign-trade zone in good faith for the purpose of exportation or storage pending exportation, and that the liquors, after deposit in the zone, have become unmerchantable or unfit...

  3. 77 FR 284 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-076] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... be considered in the overall evaluation of the transaction, including Export-Import Bank's...

  4. 78 FR 57853 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... EXPORT-IMPORT BANK [Public Notice 2013-6007] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB review and comments... Export-Import Banks of the United States (Ex-Im Bank), as part of its continuing effort to reduce...

  5. tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis.

    PubMed

    Sarkar, S; Hopper, A K

    1998-11-01

    To understand the factors specifically affecting tRNA nuclear export, we adapted in situ hybridization procedures to locate endogenous levels of individual tRNA families in wild-type and mutant yeast cells. Our studies of tRNAs encoded by genes lacking introns show that nucleoporin Nup116p affects both poly(A) RNA and tRNA export, whereas Nup159p affects only poly(A) RNA export. Los1p is similar to exportin-t, which facilitates vertebrate tRNA export. A los1 deletion mutation affects tRNA but not poly(A) RNA export. The data support the notion that Los1p and exportin-t are functional homologues. Because LOS1 is nonessential, tRNA export in vertebrate and yeast cells likely involves factors in addition to exportin-t. Mutation of RNA1, which encodes RanGAP, causes nuclear accumulation of tRNAs and poly(A) RNA. Many yeast mutants, including those with the rna1-1 mutation, affect both pre-tRNA splicing and RNA export. Our studies of the location of intron-containing pre-tRNAs in the rna1-1 mutant rule out the possibility that this results from tRNA export occurring before splicing. Our results also argue against inappropriate subnuclear compartmentalization causing defects in pre-tRNA splicing. Rather, the data support "feedback" of nucleus/cytosol exchange to the pre-tRNA splicing machinery.

  6. tRNA Nuclear Export in Saccharomyces cerevisiae: In Situ Hybridization Analysis

    PubMed Central

    Sarkar, Srimonti; Hopper, Anita K.

    1998-01-01

    To understand the factors specifically affecting tRNA nuclear export, we adapted in situ hybridization procedures to locate endogenous levels of individual tRNA families in wild-type and mutant yeast cells. Our studies of tRNAs encoded by genes lacking introns show that nucleoporin Nup116p affects both poly(A) RNA and tRNA export, whereas Nup159p affects only poly(A) RNA export. Los1p is similar to exportin-t, which facilitates vertebrate tRNA export. A los1 deletion mutation affects tRNA but not poly(A) RNA export. The data support the notion that Los1p and exportin-t are functional homologues. Because LOS1 is nonessential, tRNA export in vertebrate and yeast cells likely involves factors in addition to exportin-t. Mutation of RNA1, which encodes RanGAP, causes nuclear accumulation of tRNAs and poly(A) RNA. Many yeast mutants, including those with the rna1-1 mutation, affect both pre-tRNA splicing and RNA export. Our studies of the location of intron-containing pre-tRNAs in the rna1-1 mutant rule out the possibility that this results from tRNA export occurring before splicing. Our results also argue against inappropriate subnuclear compartmentalization causing defects in pre-tRNA splicing. Rather, the data support “feedback” of nucleus/cytosol exchange to the pre-tRNA splicing machinery. PMID:9802895

  7. 77 FR 35383 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2012-0110] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments Request. Form Title: EIB 11-05 Exporter's Certificate For Loan Guarantee & MT...

  8. 75 FR 57465 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2010-0036] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments Request. Form Title: U.S. Beneficiary Certificate and Agreement EIB 92-37. SUMMARY: The Export-Import Bank...

  9. 77 FR 59922 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2012-0521] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB.... SUMMARY: The Export-Import Bank of the United States (Ex-Im Bank), as a part of its continuing effort to...

  10. 78 FR 1859 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... EXPORT-IMPORT BANK [Public Notice 2013-0101] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB Review and Comments... Insurance Policy SUMMARY: The Export-Import Bank of the United States (Ex-Im Bank), as a part of its...

  11. 78 FR 77125 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-20

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-3007] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB... Policy. SUMMARY: The Export-Import Banks of the United States (Ex-Im Bank), as part of its continuing...

  12. 78 FR 69085 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... EXPORT-IMPORT BANK [Public Notice: 2013-3005] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB review and comments.... SUMMARY: The Export-Import Banks of the United States (Ex-Im Bank), as part of its continuing effort to...

  13. 75 FR 33375 - 30-Day Notice of Proposed Information Collection: DS-2031, Shrimp Exporter's/Importer's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ...-2031, Shrimp Exporter's/Importer's Declaration, OMB Control Number 1405-0095 ACTION: Notice of request... Information Collection: Shrimp Exporter's/ Importer's Declaration. OMB Control Number: 1405-0095. Type of... imports of shrimp pursuant to the State Department's implementation of Section 609 of Public Law 101-162...

  14. 78 FR 45168 - Acquisition Regulations: Export Control

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Control AGENCY: Department of Energy. ACTION: Notice of reopening of public comment period. SUMMARY: On... (78 FR 35195) to amend the Department of Energy Acquisition Regulation (DEAR) to add export control... ``DEAR: Export Control and RIN 1991-AB99,'' by any of the following methods: Federal eRulemaking Portal...

  15. 77 FR 37041 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2012-0111] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... Credit Insurance Policy. SUMMARY: The Export-Import Bank of the United States (Ex-Im Bank), as a part of...

  16. 77 FR 35679 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-14

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2012-0134] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for...: The Export-Import Bank of the United States (Ex-Im Bank), as a part of its continuing effort to reduce...

  17. 77 FR 54910 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of Open Special Meeting of the Sub-Saharan Africa Advisory Committee (SAAC) of the Export-Import Bank of the United States (Export-Import Bank). TIME AND PLACE: September 19, 2012 at 11 a.m. to 3 p.m. The meeting will be held at...

  18. 77 FR 76036 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2012-0555] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB.... SUMMARY: The Export-Import Bank of the United States (Ex-Im Bank), as a part of its continuing effort to...

  19. 77 FR 16549 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-21

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2012-0087] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB... Credit Insurance Policy. SUMMARY: The Export-Import Bank of the United States (Ex-Im Bank), as a part of...

  20. 76 FR 7846 - Agency Information Collection: Emergency Submission for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... EXPORT IMPORT BANK OF THE UNITED STATES [OMB Control No: 3048-0016 EIB 92-36] Agency Information Collection: Emergency Submission for OMB Review AGENCY: Export Import Bank of the United States. ACTION...., 3501-3521), this notice announces that the Export Import Bank of the United States (Ex-Im), will submit...

  1. 75 FR 54540 - Effects of Foreign Policy-Based Export Controls

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    .... 100719301-0303-02] Effects of Foreign Policy-Based Export Controls AGENCY: Bureau of Industry and Security... foreign policy-based export controls in the Export Administration Regulations to determine whether they... comments on how existing foreign policy-based export controls have affected exporters and the general...

  2. 76 FR 19356 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-0052] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB...'s Letter of Interest (LI) is a pre-export tool to help get financing off to a quick start. The LI is...

  3. Decadal-scale export of nitrogen, phosphorus, and sediment from the Susquehanna River basin, USA: Analysis and synthesis of temporal and spatial patterns

    USGS Publications Warehouse

    Zhang, Qian; Ball, William P.; Moyer, Douglas

    2016-01-01

    The export of nitrogen (N), phosphorus (P), and suspended sediment (SS) is a long-standing management concern for the Chesapeake Bay watershed, USA. Here we present a comprehensive evaluation of nutrient and sediment loads over the last three decades at multiple locations in the Susquehanna River basin (SRB), Chesapeake's largest tributary watershed. Sediment and nutrient riverine loadings, including both dissolved and particulate fractions, have generally declined at all sites upstream of Conowingo Dam (non-tidal SRB outlet). Period-of-record declines in riverine yield are generally smaller than those in source input, suggesting the possibility of legacy contributions. Consistent with other watershed studies, these results reinforce the importance of considering lag time between the implementation of management actions and achievement of river quality improvement. Whereas flow-normalized loadings for particulate species have increased recently below Conowingo Reservoir, those for upstream sites have declined, thus substantiating conclusions from prior studies about decreased reservoir trapping efficiency. In regard to streamflow effects, statistically significant log-linear relationships between annual streamflow and annual constituent load suggest the dominance of hydrological control on the inter-annual variability of constituent export. Concentration-discharge relationships revealed general chemostasis and mobilization effects for dissolved and particulate species, respectively, both suggesting transport-limitation conditions. In addition to affecting annual export rates, streamflow has also modulated the relative importance of dissolved and particulate fractions, as reflected by its negative correlations with dissolved P/total P, dissolved N/total N, particulate P/SS, and total N/total P ratios. For land-use effects, period-of-record median annual yields of N, P, and SS all correlate positively with the area fraction of non-forested land but negatively with that of forested land under all hydrological conditions. Overall, this work has informed understanding with respect to four major factors affecting constituent export (i.e., source input, reservoir modulation, streamflow, and land use) and demonstrated the value of long-term river monitoring.

  4. 78 FR 59688 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0049] Application for Final... AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States...

  5. 76 FR 41046 - Addition of the New State of the Republic of South Sudan to the Export Administration Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... Administration Regulations AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: In this final rule, the Bureau of Industry and Security (BIS) amends the Export Administration Regulations (EAR) to add controls on exports and reexports of U.S.-origin dual-use items to a new nation, the...

  6. 78 FR 69849 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2013-6008] Agency Information Collection Activities: Comment Request AGENCY: Export-Import Bank of the United States. ACTION: Submission for OMB review and comments request. [[Page 69850

  7. Inhibiting cancer cell hallmark features through nuclear export inhibition.

    PubMed

    Sun, Qingxiang; Chen, Xueqin; Zhou, Qiao; Burstein, Ezra; Yang, Shengyong; Jia, Da

    2016-01-01

    Treating cancer through inhibition of nuclear export is one of the best examples of basic research translation into clinical application. Nuclear export factor chromosomal region maintenance 1 (CRM1; Xpo1 and exportin-1) controls cellular localization and function of numerous proteins that are critical for the development of many cancer hallmarks. The diverse actions of CRM1 are likely to explain the broad ranging anti-cancer potency of CRM1 inhibitors observed in pre-clinical studies and/or clinical trials (phase I-III) on both advanced-stage solid and hematological tumors. In this review, we compare and contrast the mechanisms of action of different CRM1 inhibitors, and discuss the potential benefit of unexplored non-covalent CRM1 inhibitors. This emerging field has uncovered that nuclear export inhibition is well poised as an attractive target towards low-toxicity broad-spectrum potent anti-cancer therapy.

  8. 78 FR 2672 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0101] Application for Final..., AP078595XB AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United...

  9. 77 FR 47382 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2012-0345] Application for Final Commitment...: Export-Import Bank of the U.S. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  10. 78 FR 78955 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0060] Application for Final... AP088412XB AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United...

  11. The effect of exchange rates on southern pine exports

    Treesearch

    H.W. Wisdom; James E. Granskog

    2003-01-01

    Changes in exchange rates affect southern pine exports by changing the cost of southern wood in foreign markets. A strong dollar discourages exports; a weak dollar encourages exports. A simple economic export market model is developed to determine whether changes in the exchange rates in foreign markets of southern pine products have, in fact, let to significant...

  12. 77 FR 29314 - Meeting of the President's Export Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... DEPARTMENT OF COMMERCE International Trade Administration Meeting of the President's Export Council AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open... Webcast on the Internet at http://whitehouse.gov/live . FOR FURTHER INFORMATION CONTACT: Tricia Van Orden...

  13. 77 FR 25681 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review SunWest Foods, Inc. SUMMARY: The Office of Competition and Economic Analysis, International Trade Administration... of Competition and Economic Analysis, International Trade Administration, (202) 482-5131 (this is not...

  14. 15 CFR 30.15 - Introduction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... export control purposes. All parties to an export transaction must comply with all relevant export... convenience, references to provisions of the EAR, ITAR, CBP, and OFAC regulations that affect the statistical... information may be required for export control purposes by the regulations of CBP, BIS, State Department, or...

  15. 15 CFR 30.15 - Introduction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... export control purposes. All parties to an export transaction must comply with all relevant export... convenience, references to provisions of the EAR, ITAR, CBP, and OFAC regulations that affect the statistical... information may be required for export control purposes by the regulations of CBP, BIS, State Department, or...

  16. 15 CFR 30.15 - Introduction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... export control purposes. All parties to an export transaction must comply with all relevant export... convenience, references to provisions of the EAR, ITAR, CBP, and OFAC regulations that affect the statistical... information may be required for export control purposes by the regulations of CBP, BIS, State Department, or...

  17. 15 CFR 30.15 - Introduction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... export control purposes. All parties to an export transaction must comply with all relevant export... convenience, references to provisions of the EAR, ITAR, CBP, and OFAC regulations that affect the statistical... information may be required for export control purposes by the regulations of CBP, BIS, State Department, or...

  18. 78 FR 23916 - Secrecy and License To Export

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... DEPARTMENT OF COMMERCE Patent and Trademark Office Secrecy and License To Export ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and Trademark Office (USPTO), as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal...

  19. 78 FR 28594 - Advisory Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... draft competitiveness report, and Ex-Im Bank economic impact policy update. Public Participation: The... EXPORT-IMPORT BANK OF THE UNITED STATES Advisory Committee Meeting ACTION: Notice of Open Meeting of the Advisory Committee of the Export- Import Bank of the United States (Ex-Im Bank). Time and...

  20. 78 FR 35195 - Acquisition Regulations: Export Control

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ... Control AGENCY: Department of Energy. ACTION: Notice of proposed rulemaking. SUMMARY: The Department of... control requirements applicable to the performance of DOE contracts. DATES: Written comments on this... comments, identified by ``DEAR: Export Control and RIN 1991-AB99,'' by any of the following methods...

  1. 78 FR 5778 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... number) or email at [email protected] . SUPPLEMENTARY INFORMATION: Title III of the Export Trading Company... the Certificate from State and Federal government antitrust actions and from private treble damage... amended Certificate should be issued. FOR FURTHER INFORMATION CONTACT: Joseph Flynn, Director, Office of...

  2. Comparison between Canadian Canola Harvest and Export Surveys.

    PubMed

    Barthet, Véronique J

    2016-07-20

    Parameters, such as oil, protein, glucosinolates, chlorophyll content and fatty acid composition, were determined using reference methods for both harvest survey samples and Canadian Canola exports. Canola harvest survey and export data were assessed to evaluate if canola harvest survey data can be extrapolated to predict the quality of the Canadian canola exports. There were some differences in some measured parameters between harvest and export data, while other parameters showed little difference. Protein content and fatty acid composition showed very similar data for harvest and export averages. Canadian export data showed lower oil content when compared to the oil content of harvest survey was mainly due to a diluting effect of dockage in the export cargoes which remained constant over the years (1.7% to 1.9%). Chlorophyll was the least predictable parameter; dockage quality as well as commingling of the other grades in Canola No. 1 Canada affected the chlorophyll content of the exports. Free fatty acids (FFA) were also different for the export and harvest survey. FFA levels are affected by storage conditions; they increase during the shipping season and, therefore, are difficult to predict from their harvest survey averages.

  3. Comparison between Canadian Canola Harvest and Export Surveys

    PubMed Central

    Barthet, Véronique J.

    2016-01-01

    Parameters, such as oil, protein, glucosinolates, chlorophyll content and fatty acid composition, were determined using reference methods for both harvest survey samples and Canadian Canola exports. Canola harvest survey and export data were assessed to evaluate if canola harvest survey data can be extrapolated to predict the quality of the Canadian canola exports. There were some differences in some measured parameters between harvest and export data, while other parameters showed little difference. Protein content and fatty acid composition showed very similar data for harvest and export averages. Canadian export data showed lower oil content when compared to the oil content of harvest survey was mainly due to a diluting effect of dockage in the export cargoes which remained constant over the years (1.7% to 1.9%). Chlorophyll was the least predictable parameter; dockage quality as well as commingling of the other grades in Canola No. 1 Canada affected the chlorophyll content of the exports. Free fatty acids (FFA) were also different for the export and harvest survey. FFA levels are affected by storage conditions; they increase during the shipping season and, therefore, are difficult to predict from their harvest survey averages. PMID:27447675

  4. Export Time of Earthquake-Derived Landslides in Active Mountain Ranges

    NASA Astrophysics Data System (ADS)

    Croissant, T.; Lague, D.; Steer, P.; Davy, P.

    2016-12-01

    In active mountain ranges, large earthquakes (Mw > 5-6) trigger numerous landslides that impact river dynamics. These landslides bring local and sudden sediment deposits which are eroded and transported along the river network, causing downstream changes in river geometry, transport capacity and erosion efficiency. The progressive removal of landslide materials has implications for downstream hazards management and for landscape dynamics at the timescale of the seismic cycle. Although the export time of suspended sediments from landslides triggered by large-magnitude earthquakes has been extensively studied, the processes and time scales associated to bedload transport remains poorly studied. Here, we study the sediment export of large landslides with the 2D morphodynamic model, Eros. This model combines: (i) an hydrodynamic model, (ii) a sediment transport and deposition model and (iii) a lateral erosion model. Eros is particularly well suited for this issue as it accounts for the complex retro-actions between sediment transport and fluvial geometry for rivers submitted to external forcings such as abrupt sediment supply increase. Using a simplified synthetic topography we systematically study the influence of pulse volume (Vs) and channel transport capacity (QT) on the export time of landslides. The range of simulated river behavior includes landslide vertical incision, its subsequent removal by lateral erosion and the river morphology modifications induced by downstream sediment propagation. The morphodynamic adaptation of the river increases its transport capacity along the channel and tends to accelerate the landslide evacuation. Our results highlight two regimes: (i) the export time is linearly related to Vs/QT when the sediment pulse introduced in the river does not affect significantly the river hydrodynamic (low Vs/QT) and (ii) the export time is a non-linear function of Vs/QT when the pulse undergoes significant morphodynamic modifications during its evacuation (high Vs/QT). By combining our newly derived export time functions with the frequency-magnitude of earthquake intensity and the induced sediment production, we investigate the sediment export of several plausible earthquake scenarii in different mountain ranges (New Zealand, Taiwan, Nepal).

  5. 75 FR 12433 - National Export Initiative

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... Order 13534 of March 11, 2010 National Export Initiative By the authority vested in me as President by... performance will, in turn, create good high-paying jobs. The National Export Initiative (NEI) shall be an Administration initiative to improve conditions that directly affect the private sector's ability to export. The...

  6. 77 FR 54559 - Proposed Information Collection; Comment Request; Offsets in Military Exports

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Proposed Information Collection; Comment Request; Offsets in Military Exports AGENCY: Bureau of Industry and Security, Department of Commerce. ACTION: Notice. SUMMARY: The Department of Commerce, as part of its continuing effort to reduce paperwork...

  7. 75 FR 51025 - Application to Export Electric Energy; Vitol Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... adversely impact on the reliability of the U.S. electric power supply system. Copies of this application... DEPARTMENT OF ENERGY [OE Docket No. EA-370] Application to Export Electric Energy; Vitol Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application...

  8. 78 FR 65978 - Application to Export Electric Energy; Brookfield Energy Marketing Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-258-D] Application to Export Electric Energy; Brookfield Energy Marketing Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing Inc. (BEMI) has applied to renew its authority...

  9. 76 FR 11437 - Application To Export Electric Energy; Societe Generale Energy Corp.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-376] Application To Export Electric Energy; Societe Generale Energy Corp. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Societe Generale Energy Corp. (SGEC) has applied for authority to transmit electric...

  10. 75 FR 57912 - Application To Export Electric Energy; Rainbow Energy Marketing Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-375] Application To Export Electric Energy; Rainbow Energy Marketing Corporation AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Rainbow Energy Marketing Corporation (Rainbow) has applied for authority to transmit...

  11. 76 FR 3882 - Application To Export Electric Energy; Intercom Energy, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-289-B] Application To Export Electric Energy; Intercom Energy, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Intercom Energy, Inc. (Intercom) has applied to renew its authority to transmit electric...

  12. Decadal-scale export of nitrogen, phosphorus, and sediment from the Susquehanna River basin, USA: Analysis and synthesis of temporal and spatial patterns.

    PubMed

    Zhang, Qian; Ball, William P; Moyer, Douglas L

    2016-09-01

    The export of nitrogen (N), phosphorus (P), and suspended sediment (SS) is a long-standing management concern for the Chesapeake Bay watershed, USA. Here we present a comprehensive evaluation of nutrient and sediment loads over the last three decades at multiple locations in the Susquehanna River basin (SRB), Chesapeake's largest tributary watershed. Sediment and nutrient riverine loadings, including both dissolved and particulate fractions, have generally declined at all sites upstream of Conowingo Dam (non-tidal SRB outlet). Period-of-record declines in riverine yield are generally smaller than those in source input, suggesting the possibility of legacy contributions. Consistent with other watershed studies, these results reinforce the importance of considering lag time between the implementation of management actions and achievement of river quality improvement. Whereas flow-normalized loadings for particulate species have increased recently below Conowingo Reservoir, those for upstream sites have declined, thus substantiating conclusions from prior studies about decreased reservoir trapping efficiency. In regard to streamflow effects, statistically significant log-linear relationships between annual streamflow and annual constituent load suggest the dominance of hydrological control on the inter-annual variability of constituent export. Concentration-discharge relationships revealed general chemostasis and mobilization effects for dissolved and particulate species, respectively, both suggesting transport-limitation conditions. In addition to affecting annual export rates, streamflow has also modulated the relative importance of dissolved and particulate fractions, as reflected by its negative correlations with dissolved P/total P, dissolved N/total N, particulate P/SS, and total N/total P ratios. For land-use effects, period-of-record median annual yields of N, P, and SS all correlate positively with the area fraction of non-forested land but negatively with that of forested land under all hydrological conditions. Overall, this work has informed understanding with respect to four major factors affecting constituent export (i.e., source input, reservoir modulation, streamflow, and land use) and demonstrated the value of long-term river monitoring. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  13. Future riverine nitrogen export to US coastal regions ...

    EPA Pesticide Factsheets

    Excess nitrogen (N) in the environment degrades ecosystems and adversely affects human health. Here we examine predictions of contemporary (2000) and future (2030) coastal N loading in the continental US by the Nutrient Export from WaterSheds (NEWS) model. Future output is from storylines of the Millennium Ecosystem Assessment (MEA) and two additional scenarios that reflect “business as usual” and “ambitious” approaches to nutrient management. Modeled total nitrogen (TN) export by rivers to US coastal areas ranged between 2.5 Tg N y-1 in 2000 and 1.9 - 3.0 Tg N y-1 in 2030, depending on scenario. Differences among scenarios reflect the interactions of increased food and energy demands associated with population growth and efforts to reduce losses of N to the environment. Depending on year and scenario, agriculture supplies 25-43% of coastal TN, atmospheric N deposition 6-8%, human sewage 6-12%, and natural and particulate N sources account for the remainder. Our analysis suggests that achieving reductions in coastal N loading will require aggressive management actions. Coastal TN export could be reduced 22% between 2000 and 2030 to 1.9 Tg N y-1 if currently available best management practices and technologies are fully implemented to control N from agriculture, fossil fuel emissions, and wastewater effluent. If N management capabilities do not improve by 2030, coastal N loads could increase 20% to 3.0 Tg N y-1, due primarily to increases in N from agricu

  14. 76 FR 65725 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-076] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB...'s determination of the appropriate term for the transaction. The form can be view at: http://www...

  15. To amend the Export Apple Act to permit the export of apples to Canada in bulk bins without certification by the Department of Agriculture.

    THOMAS, 113th Congress

    Rep. Owens, William L. [D-NY-21

    2013-03-20

    House - 04/02/2013 Referred to the Subcommittee on Horticulture, Research, Biotechnology, and Foreign Agriculture. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. 76 FR 23641 - Proposed Information Collection: Export Declaration of Defense Technical Data or Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... DEPARTMENT OF STATE [Public Notice: 7431] Proposed Information Collection: Export Declaration of Defense Technical Data or Services AGENCY: Department of State. ACTION: Notice of request for public..., Directorate of Defense Trade Controls, Bureau of Political-Military Affairs, U.S. Department of State...

  17. 75 FR 61706 - Request for Public Comments Regarding Small and Medium Enterprises' Understanding of and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... Public Comments Regarding Small and Medium Enterprises' Understanding of and Compliance With the Export Administration Regulations AGENCY: Bureau of Industry and Security, Commerce. ACTION: Notice of Inquiry. SUMMARY... the public regarding small and medium enterprises' (SMEs) understanding of and compliance with export...

  18. 75 FR 57911 - Application to Export Electric Energy; EDF Trading North America, LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... the proposed action will not adversely impact on the reliability of the U.S. electric power supply... from electric utilities, Federal power marketing agencies and other entities within the United States... DEPARTMENT OF ENERGY [OE Docket No. EA-373] Application to Export Electric Energy; EDF Trading...

  19. 77 FR 60689 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB Review and Comments Request... previous calendar year with an electronic invitation to participate in the online survey. The proposed... Review: Renewal. Need and Use: This information will be used to fulfill the statutory mandate (Export...

  20. 77 FR 1474 - Application To Export Electric Energy; AEP Energy Partners, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-318-B] Application To Export Electric Energy; AEP Energy Partners, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: AEP Energy Partners, Inc. (AEPEP) has applied to renew its authority to transmit...

  1. 77 FR 50487 - Application To Export Electric Energy; RBC Energy Services LP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-328-A] Application To Export Electric Energy; RBC Energy Services LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: RBC Energy Services LP (RBC Energy) has applied to renew its authority to transmit...

  2. 75 FR 76962 - Application To Export Electric Energy; MAG Energy Solutions, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-306-A] Application To Export Electric Energy; MAG Energy Solutions, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: MAG Energy Solutions, Inc. (MAG E.S.) has applied to renew its authority to transmit...

  3. 76 FR 50476 - Application To Export Electric Energy; Glacial Energy of Texas, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-382] Application To Export Electric Energy; Glacial Energy of Texas, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: Glacial Energy of Texas, Inc. (Glacial) has applied for authority to transmit electric...

  4. 78 FR 64207 - Application To Export Electric Energy; TEC Energy Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-388] Application To Export Electric Energy; TEC Energy Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: TEC Energy Inc. (TEC) has applied for authority to transmit electric energy from the United...

  5. 77 FR 20805 - Application to Export Electric Energy; PPL EnergyPlus, LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-210-C] Application to Export Electric Energy; PPL EnergyPlus, LLC AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: PPL EnergyPlus, LLC. (PPL EnergyPlus) has applied to renew its authority to transmit...

  6. Using Coupled Models to Study the Effects of River Discharge on Biogeochemical Cycling and Hypoxia in the Northern Gulf of Mexico

    NASA Technical Reports Server (NTRS)

    Penta, Bradley; Ko, D.; Gould, Richard W.; Arnone, Robert A.; Greene, R.; Lehrter, J.; Hagy, James; Schaeffer, B.; Murrell, M.; Kurtz, J.; hide

    2009-01-01

    We describe emerging capabilities to understand physical processes and biogeoehemical cycles in coastal waters through the use of satellites, numerical models, and ship observations. Emerging capabilities provide significantly improved ability to model ecological systems and the impact of environmental management actions on them. The complex interaction of physical and biogeoehemical processes responsible for hypoxic events requires an integrated approach to research, monitoring, and modeling in order to fully define the processes leading to hypoxia. Our efforts characterizes the carbon cycle associated with river plumes and the export of organic matter and nutrients form coastal Louisiana wetlands and embayments in a spatially and temporally intensive manner previously not possible. Riverine nutrients clearly affect ecosystems in the northern Gulf of Mexico as evidenced in the occurrence of regional hypoxia events. Less known and largely unqualified is the export of organic matter and nutrients from the large areas of disappearing coastal wetlands and large embayments adjacent to the Louisiana Continental Shelf. This project provides new methods to track the river plume along the shelf and to estimate the rate of export of suspended inorganic and organic paniculate matter and dissolved organic matter form coastal habitats of south Louisiana.

  7. American export control, technology spillover and innovation of Chinese pharmaceutical Industry.

    PubMed

    Hui, Jiang

    2017-05-01

    This paper was aimed to analyze whether the U.S. strict export control to China affects the technological innovation of Chinese pharmaceutical industry. This paper selected the data of technological innovation and the expenditure of high and new technology adoption in China's pharmaceutical industry from 1995 to 2014, created panel regression model to study the impact of export controls on technology spillovers and the impact of technology spillovers on innovation capacity. The results show that US export control has a significant impact on technology spillovers, but foreign technology spillovers have no significant impact on the innovation of Chinese pharmaceutical industry. Although the US export control prevented foreign technology spillovers to China, but indirectly stimulated the domestic technology spillovers to pharmaceutical manufacturing industry in China. Statistical analysis show that the correlation coefficient between innovation capacity and expenditure for high technology adoption is not significant, but the expenditure of purchasing domestic technical is essential to pharmaceutical innovation. This study shows that US export control indirectly, not directly, affected the technological innovation of China's pharmaceutical industry, affected the allocation of innovative resources, but failed to prevent the technological progress and competitiveness improvement of Chinese pharmaceutical industry.

  8. Ketamine produces antidepressant-like effects through phosphorylation-dependent nuclear export of histone deacetylase 5 (HDAC5) in rats

    PubMed Central

    Choi, Miyeon; Lee, Seung Hoon; Wang, Sung Eun; Ko, Seung Yeon; Song, Mihee; Choi, June-Seek; Duman, Ronald S.; Son, Hyeon

    2015-01-01

    Ketamine produces rapid antidepressant-like effects in animal assays for depression, although the molecular mechanisms underlying these behavioral actions remain incomplete. Here, we demonstrate that ketamine rapidly stimulates histone deacetylase 5 (HDAC5) phosphorylation and nuclear export in rat hippocampal neurons through calcium/calmodulin kinase II- and protein kinase D-dependent pathways. Consequently, ketamine enhanced the transcriptional activity of myocyte enhancer factor 2 (MEF2), which leads to regulation of MEF2 target genes. Transfection of a HDAC5 phosphorylation-defective mutant (Ser259/Ser498 replaced by Ala259/Ala498, HDAC5-S/A), resulted in resistance to ketamine-induced nuclear export, suppression of ketamine-mediated MEF2 transcriptional activity, and decreased expression of MEF2 target genes. Behaviorally, viral-mediated hippocampal knockdown of HDAC5 blocked or occluded the antidepressant effects of ketamine both in unstressed and stressed animals. Taken together, our results reveal a novel role of HDAC5 in the actions of ketamine and suggest that HDAC5 could be a potential mechanism contributing to the therapeutic actions of ketamine. PMID:26647181

  9. 75 FR 62512 - Sabine Pass Liquefaction, LLC; Application for Long-Term Authorization To Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Long-Term Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives... Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence Avenue, SW., Washington, DC 20585. FOR...

  10. A bill to amend the Export Apple Act to permit the export of apples to Canada in bulk bins without certification by the Department of Agriculture.

    THOMAS, 112th Congress

    Sen. Gillibrand, Kirsten E. [D-NY

    2012-03-20

    Senate - 03/20/2012 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. 75 FR 36511 - Revisions to the Export Administration Regulations Based Upon a Systematic Review of the Commerce...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Parts 734, 738, 740, 742, 772, and... Based Upon a Systematic Review of the Commerce Control List: Additional Changes AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: This rule amends the Export Administration...

  12. 77 FR 72917 - Editorial Corrections to the Commerce Control List of the Export Administration Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Part 774 [Docket No. 120320200-2296-01] RIN 0694-AF62 Editorial Corrections to the Commerce Control List of the Export Administration Regulations AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: This final rule...

  13. 76 FR 58488 - Dominion Cove Point LNG, LP; Application for Blanket Authorization to Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... Blanket Authorization to Export Previously Imported Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of... Natural Gas Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375...

  14. 76 FR 62048 - ConocoPhillips Company; Application for Blanket Authorization To Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department...), Office of Natural Gas Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC...

  15. 78 FR 64207 - Application To Export Electric Energy; New Brunswick Energy Marketing Corporation (f/k/a New...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-345-A] Application To Export Electric Energy; New Brunswick Energy Marketing Corporation (f/k/a New Brunswick Power Generation Corp.) AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: New Brunswick Energy...

  16. 75 FR 56912 - Live Goats and Swine for Export; Removal of Certain Testing Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service 9 CFR Part 91 [Docket No... AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Proposed rule. SUMMARY: We are... tuberculosis and brucellosis testing of goats and breeding swine intended for export to countries that do not...

  17. 77 FR 50486 - Application To Export Electric Energy; TexMex Energy, LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-294-B] Application To Export Electric Energy; TexMex Energy, LLC AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: TexMex Energy, LLC (TexMex) has applied to renew its authority to transmit electric energy from...

  18. 76 FR 4110 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... EXPORT-IMPORT BANK OF THE U.S. [Public Notice 2011-0002] Agency Information Collection Activities: Final Collection; Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB...-Import Bank of the United States (Ex-Im Bank), as a part of its continuing effort to reduce paperwork and...

  19. International Impacts of Global Climate Change: Testimony to House Appropriations Subcommittee on Foreign Operations, Export Financing and Related Programs

    DOE R&D Accomplishments Database

    Fulkerson, W.; Cushman, R. M.; Marland, G.; Rayner, S.

    1989-02-21

    International impacts of global climate change are those for which the important consequences arise because of national sovereignty. Such impacts could be of two types: (1) migrations across national borders of people, of resources (such as agricultural productivity, or surface water, or natural ecosystems), of effluents, or of patterns of commerce; and (2) changes to the way nations use and manage their resources, particularly fossil fuels and forests, as a consequence of international concern over the global climate. Actions by a few resource-dominant nations may affect the fate of all. These two types of international impacts raise complex equity issues because one nation may perceive itself as gaining at the expense of its neighbors, or it may perceive itself as a victim of the actions of others.

  20. Climate change and dissolved organic carbon export to the Gulf of Maine

    USGS Publications Warehouse

    Huntington, Thomas G.; Balch, William M.; Aiken, George R.; Sheffield, Justin; Luo, Lifeng; Roesler, Collin S.; Camill, Philip

    2016-01-01

    Ongoing climate change is affecting the concentration, export (flux), and timing of dissolved organic carbon (DOC) exported to the Gulf of Maine (GoM) through changes in hydrologic regime. DOC export was calculated for water years 1950 through 2013 for 20 rivers and for water years 1930 through 2013 for 14 rivers draining to the GoM. DOC export was also estimated for the 21st century based on climate and hydrologic modeling in a previously published study. DOC export was calculated by using the regression model LOADEST to fit seasonally adjusted concentration discharge (C-Q) relations. Our results are an analysis of the sensitivity of DOC export to changes in hydrologic conditions over time since land cover and vegetation were held constant over time. Despite large interannual variability, all rivers had increasing DOC export during winter and these trends were significant (p < 0.05) in 10 out of 20 rivers for 1950 to 2013 and in 13 out of 14 rivers for 1930 to 2013. All rivers also had increasing annual export of DOC although fewer trends were statistically significant than for winter export. Projections for DOC export during the 21st century were variable depending on the climate model and greenhouse gas emission scenario that affected future river discharge through effects on precipitation and evapotranspiration. The most consistent result was a significant increase in DOC export in winter in all model-by-emission scenarios. DOC export was projected to decrease during the summer in all model-by-emission scenarios, with statistically significant decreases in half of the scenarios.

  1. 75 FR 44935 - Notice of Request for Extension of Approval of an Information Collection; Certificate for Poultry...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... Hatching Eggs for Export AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of... poultry hatching eggs from the United States. DATES: We will consider all comments that we receive on or... FURTHER INFORMATION CONTACT: For information on the export of poultry and poultry hatching eggs from the...

  2. 75 FR 13755 - Freeport LNG Development, L.P.; Application To Amend Blanket Authorization To Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... Amend Blanket Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of Application to Amend Blanket Authorization. SUMMARY: The Office of Fossil Energy (FE) of the... Oil and Gas Global Security and Supply, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000...

  3. 77 FR 53874 - The Dow Chemical Company; Application for Blanket Authorization To Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department... Security and Supply, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence Avenue SW...

  4. 77 FR 76013 - Sempra LNG Marketing, LLC; Application for Blanket Authorization To Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department.... Department of Energy (FE-34), Office of Oil and Gas Global Security and Supply, Office of Fossil Energy...

  5. 75 FR 62510 - Chevron U.S.A. Inc.; Application for Blanket Authorization To Export Liquefied Natural Gas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives notice of... Security and Supply, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence Avenue, SW...

  6. 77 FR 66597 - Chevron U.S.A. Inc.; Application for Blanket Authorization To Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department.... Department of Energy (FE-34), Office of Oil and Gas Global Security and Supply, Office of Fossil Energy...

  7. 78 FR 53739 - Orders Granting Authority To Import and Export Natural Gas, To Import and Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ...: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives notice that during July 2013, it issued orders... Web site at http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders-2013.html . They...

  8. 76 FR 22339 - Effectiveness of Licensing Procedures for Exportation of Agricultural Commodities, Medicine, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ... Sudan and Iran; Comment Request AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Request for... exportation of agricultural commodities, medicine, and medical devices to Sudan and Iran. Pursuant to section... commodities, medicine, and medical devices to Sudan and Iran are set forth in 31 CFR 538.523-526 and 31 CFR...

  9. 76 FR 33746 - Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Liquefied Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... Blanket Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives... Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or...

  10. 76 FR 2093 - Eni USA Gas Marketing LLC; Application for Blanket Authorization To Export Liquefied Natural Gas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives notice of.... Department of Energy (FE-34), Office of Oil and Gas Global Security and Supply, Office of Fossil Energy...

  11. 77 FR 32962 - Gulf Coast LNG Export, LLC; Application for Long-Term Authorization To Export Domestically...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ...: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of... Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or... Gas Regulatory Activities, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence...

  12. 75 FR 60095 - Sempra LNG Marketing, LLC; Application for Blanket Authorization To Export Liquefied Natural Gas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Authorization To Export Liquefied Natural Gas AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives notice of... Gas Global Security and Supply, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000...

  13. 77 FR 25711 - Cheniere Marketing, LLC; Application for Blanket Authorization To Export Previously Imported...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department... Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or Private...

  14. 77 FR 63921 - Proposed Collection; Comment Request for Notice 2000-28

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... rules under the Code for making a nontaxable sale of coal for export or for obtaining a credit or refund when tax has been paid with respect to a nontaxable sale of coal for export. Current Actions: There are... of information on respondents, including through the use of automated collection techniques or other...

  15. 77 FR 15336 - Revision to the Export Provisions of the Cathode Ray Tube (CRT) Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... reuse and recycling. Additionally, EPA would gather more information on shipments of CRTs that are sent... who export used cathode ray tubes (CRTs) and CRT glass for reuse or recycling. This action does not... tubes (CRTs) for reuse or recycling. The existing requirements were first promulgated on July 28, 2006...

  16. 76 FR 10082 - Office of International Trade; State Trade and Export Promotion (STEP) Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... (STEP) Grant Program AGENCY: U.S. Small Business Administration (SBA). ACTION: Notice of grant... Program Announcement No. OIT-STEP-2011- 01 to invite the States, the District of Columbia and the U.S. Territories to apply for a STEP grant to carry out export promotion programs that assist eligible small...

  17. 75 FR 78979 - Application to Export Electric Energy; Twin Rivers Paper Company Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    .... Twin Rivers has requested an export authorization in order to be able to supply emergency power as... proposed action will not adversely impact on the reliability of the U.S. electric power supply system... electric energy from the United States to Canada pursuant to section 202(e) of the Federal Power Act. DATES...

  18. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Typical classes of action. 408.6 Section 408.6 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES PROCEDURES FOR COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3...

  19. Exporting DBCP and other banned pesticides: consideration of ethical issues.

    PubMed

    Lowry, L K; Frank, A L

    1999-01-01

    Many developed countries permit the export of pesticides that are banned, restricted, or unregistered within their own borders. This practice, which leads to the exposure of agricultural workers in developing countries to high levels of pesticides that are not permitted in the country of manufacture, raises many ethical issues as well as economic, social, political, and public health issues. Worldwide attempts to control export of such pesticides, through the FAO/UNEP Prior Informed Consent program, moves this issue in the right direction. This article explores the current U.S. and international practices, using the specific example of export of DBCP to banana-producing countries. The actions taken by multinational corporations, manufacturers of the pesticides, and public health officials in both the exporting and importing countries are explored, along with the impacts on workers, local economies, governments, and the environment.

  20. 78 FR 65304 - Orders Granting Authority To Import and Export Natural Gas, and To Import and Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... And Electric Company........ 13-95-NG Barclays Bank PLC 13-99-NG AGENCY: Office of Fossil Energy, Department of Energy. ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department... attached appendix and may be found on the FE Web site at http://www.fossil.energy.gov/programs...

  1. 78 FR 4401 - Orders Granting Authority To Import and Export Natural Gas, To Import and Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... 12-144-NG MC GLOBAL GAS CORPORATION 12-150-NG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy... on the FE Web site at http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders-2012...

  2. 78 FR 44940 - Orders Granting Authority To Import and Export Natural Gas, and To Import and Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... 13-64-NG PENTACLES ENERGY, LLLP 13-65-NG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives... found on the FE Web site at http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders...

  3. 78 FR 33090 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... EXPORT-IMPORT BANK [Public Notice 2013-0030] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP087980XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10...

  4. 78 FR 67144 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... EXPORT-IMPORT BANK [Public Notice 2013-0050] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP086418XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10...

  5. 78 FR 16501 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... EXPORT-IMPORT BANK [Public Notice 2013-0022] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 million: AP086115XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10...

  6. 78 FR 54465 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... EXPORT-IMPORT BANK [Public Notice: 2013-0041] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP086031XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3...

  7. 78 FR 75344 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... EXPORT-IMPORT BANK [Public Notice: 2013-0057] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP088400XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3...

  8. 78 FR 76614 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0059] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  9. 78 FR 69850 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... EXPORT-IMPORT BANK [Public Notice: 2013-0054] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP086750XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3...

  10. 78 FR 16675 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0023] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  11. 78 FR 21948 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0027] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  12. 77 FR 74010 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2012-0546] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  13. 78 FR 23763 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-22

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0028] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  14. 78 FR 16852 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0024] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  15. 78 FR 27236 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... EXPORT-IMPORT BANK [Public Notice 2013-0029] Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100 Million: AP087013XX AGENCY: Export-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10...

  16. 78 FR 56227 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice: 2013-0045] Application for Final...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  17. 76 FR 54734 - Proposed Information Collection; Comment Request; Application for Export Trade; Certificate of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... private suits, by limiting liability in private actions to actual damages when the challenged activities are covered by an Export Trade Certificate of Review. II. Method of Collection The form is sent by request to U.S. firms. III. Data OMB Control Number: 0625-0125. Form Number(s): ITA-4093P. Type of Review...

  18. Regulation of the Expression of Bacterial Multidrug Exporters by Two-Component Signal Transduction Systems.

    PubMed

    Nishino, Kunihiko

    2018-01-01

    Bacterial multidrug exporters confer resistance to a wide range of antibiotics, dyes, and biocides. Recent studies have shown that there are many multidrug exporters encoded in bacterial genome. For example, it was experimentally identified that E. coli has at least 20 multidrug exporters. Because many of these multidrug exporters have overlapping substrate spectra, it is intriguing that bacteria, with their economically organized genomes, harbor such large sets of multidrug exporter genes. The key to understanding how bacteria utilize these multiple exporters lies in the regulation of exporter expression. Bacteria have developed signaling systems for eliciting a variety of adaptive responses to their environments. These adaptive responses are often mediated by two-component regulatory systems. In this chapter, the method to identify response regulators that affect expression of multidrug exporters is described.

  19. Integration of mRNP formation and export.

    PubMed

    Björk, Petra; Wieslander, Lars

    2017-08-01

    Expression of protein-coding genes in eukaryotes relies on the coordinated action of many sophisticated molecular machineries. Transcription produces precursor mRNAs (pre-mRNAs) and the active gene provides an environment in which the pre-mRNAs are processed, folded, and assembled into RNA-protein (RNP) complexes. The dynamic pre-mRNPs incorporate the growing transcript, proteins, and the processing machineries, as well as the specific protein marks left after processing that are essential for export and the cytoplasmic fate of the mRNPs. After release from the gene, the mRNPs move by diffusion within the interchromatin compartment, making up pools of mRNPs. Here, splicing and polyadenylation can be completed and the mRNPs recruit the major export receptor NXF1. Export competent mRNPs interact with the nuclear pore complex, leading to export, concomitant with compositional and conformational changes of the mRNPs. We summarize the integrated nuclear processes involved in the formation and export of mRNPs.

  20. Effect of Increased Levels of Liquefied Natural Gas Exports on U.S. Energy Markets

    EIA Publications

    2014-01-01

    This report responds to a May 29, 2014 request from the U.S. Department of Energy's Office of Fossil Energy (DOE/FE) for an update of the Energy Information Administration's (EIA) January 2012 study of liquefied natural gas (LNG) export scenarios. This updated study, like the prior one, is intended to serve as an input to be considered in the evaluation of applications to export LNG from the United States under Section 3 of the Natural Gas Act, which requires DOE to grant a permit to export domestically produced natural gas unless it finds that such action is not consistent with the public interest. Appendix A provides a copy of the DOE/FE request letter.

  1. 10 CFR 110.84 - Commission action on a hearing request or intervention petition.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Commission action on a hearing request or intervention... Commission action on a hearing request or intervention petition. (a) In an export licensing proceeding, or in an import licensing proceeding in which a hearing request or intervention petition does not assert or...

  2. 10 CFR 110.84 - Commission action on a hearing request or intervention petition.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Commission action on a hearing request or intervention... Commission action on a hearing request or intervention petition. (a) In an export licensing proceeding, or in an import licensing proceeding in which a hearing request or intervention petition does not assert or...

  3. 10 CFR 110.84 - Commission action on a hearing request or intervention petition.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Commission action on a hearing request or intervention... Commission action on a hearing request or intervention petition. (a) In an export licensing proceeding, or in an import licensing proceeding in which a hearing request or intervention petition does not assert or...

  4. 10 CFR 110.84 - Commission action on a hearing request or intervention petition.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Commission action on a hearing request or intervention... Commission action on a hearing request or intervention petition. (a) In an export licensing proceeding, or in an import licensing proceeding in which a hearing request or intervention petition does not assert or...

  5. 10 CFR 110.84 - Commission action on a hearing request or intervention petition.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Commission action on a hearing request or intervention... Commission action on a hearing request or intervention petition. (a) In an export licensing proceeding, or in an import licensing proceeding in which a hearing request or intervention petition does not assert or...

  6. Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifolia.

    PubMed

    Tamura, Satoru; Kaneko, Masafumi; Shiomi, Atsushi; Yang, Guang-Ming; Yamaura, Toshiaki; Murakami, Nobutoshi

    2010-03-15

    Bioassay-guided separation from the MeOH extract of the South American medicinal plant Sida cordifolia resulted in isolation of (10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid (1) as an unprecedented NES non-antagonistic inhibitor for nuclear export of Rev. This mechanism of action was established by competitive experiment by the biotinylated probe derived from leptomycin B, the known NES antagonistic inhibitor. Additionally, structure-activity relationship analysis by use of the synthesized analogs clarified cooperation of several functionalities in the Rev-export inhibitory activity of 1. Copyright 2010 Elsevier Ltd. All rights reserved.

  7. Mesoscale Effects on Carbon Export: A Global Perspective

    NASA Astrophysics Data System (ADS)

    Harrison, Cheryl S.; Long, Matthew C.; Lovenduski, Nicole S.; Moore, Jefferson K.

    2018-04-01

    Carbon export from the surface to the deep ocean is a primary control on global carbon budgets and is mediated by plankton that are sensitive to physical forcing. Earth system models generally do not resolve ocean mesoscale circulation (O(10-100) km), scales that strongly affect transport of nutrients and plankton. The role of mesoscale circulation in modulating export is evaluated by comparing global ocean simulations conducted at 1° and 0.1° horizontal resolution. Mesoscale resolution produces a small reduction in globally integrated export production (<2%) however, the impact on local export production can be large (±50%), with compensating effects in different ocean basins. With mesoscale resolution, improved representation of coastal jets block off-shelf transport, leading to lower export in regions where shelf-derived nutrients fuel production. Export is further reduced in these regions by resolution of mesoscale turbulence, which restricts the spatial area of production. Maximum mixed layer depths are narrower and deeper across the Subantarctic at higher resolution, driving locally stronger nutrient entrainment and enhanced summer export production. In energetic regions with seasonal blooms, such as the Subantarctic and North Pacific, internally generated mesoscale variability drives substantial interannual variation in local export production. These results suggest that biogeochemical tracer dynamics show different sensitivities to transport biases than temperature and salinity, which should be considered in the formulation and validation of physical parameterizations. Efforts to compare estimates of export production from observations and models should account for large variability in space and time expected for regions strongly affected by mesoscale circulation.

  8. 78 FR 21349 - Orders Granting Authority To Import and Export Natural Gas, To Export Liquefied Natural Gas, To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ...-187-LNG DYNEGY MARKETING AND TRADE, LLC 13-02-NG PROGAS USA INC 13-03-NG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE... orders are summarized in the attached appendix and may be found on the FE Web site at http://www.fossil...

  9. 78 FR 1211 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... EXPORT-IMPORT BANK OF THE UNITED STATES [Public Notice 2012-0558] Application for Final Commitment...-Import Bank of the United States. ACTION: Notice. SUMMARY: This Notice is to inform the public, in accordance with Section 3(c)(10) of the Charter of the Export-Import Bank of the United States (``Ex-Im Bank...

  10. Small Manufacturers Export Initiative Act

    THOMAS, 111th Congress

    Rep. Larsen, Rick [D-WA-2

    2010-07-20

    House - 07/23/2010 Referred to the Subcommittee on Technology and Innovation. (All Actions) Notes: For further action, see H.R.5297, which became Public Law 111-240 on 9/27/2010. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β) pathway.

    PubMed

    Kim, Man-Su; Shutov, Leonid P; Gnanasekaran, Aswini; Lin, Zhihong; Rysted, Jacob E; Ulrich, Jason D; Usachev, Yuriy M

    2014-11-07

    The Ca(2+)/calcineurin-dependent transcription factor nuclear factor of activated T-cells (NFAT) plays an important role in regulating many neuronal functions, including excitability, axonal growth, synaptogenesis, and neuronal survival. NFAT can be activated by action potential firing or depolarization that leads to Ca(2+)/calcineurin-dependent dephosphorylation of NFAT and its translocation to the nucleus. Recent data suggest that NFAT and NFAT-dependent functions in neurons can also be potently regulated by NGF and other neurotrophins. However, the mechanisms of NFAT regulation by neurotrophins are not well understood. Here, we show that in dorsal root ganglion sensory neurons, NGF markedly facilitates NFAT-mediated gene expression induced by mild depolarization. The effects of NGF were not associated with changes in [Ca(2+)]i and were independent of phospholipase C activity. Instead, the facilitatory effect of NGF depended on activation of the PI3K/Akt pathway downstream of the TrkA receptor and on inhibition of glycogen synthase kinase 3β (GSK3β), a protein kinase known to phosphorylate NFAT and promote its nuclear export. Knockdown or knockout of NFATc3 eliminated this facilitatory effect. Simultaneous monitoring of EGFP-NFATc3 nuclear translocation and [Ca(2+)]i changes in dorsal root ganglion neurons indicated that NGF slowed the rate of NFATc3 nuclear export but did not affect its nuclear import rate. Collectively, our data suggest that NGF facilitates depolarization-induced NFAT activation by stimulating PI3K/Akt signaling, inactivating GSK3β, and thereby slowing NFATc3 export from the nucleus. We propose that NFAT serves as an integrator of neurotrophin action and depolarization-driven calcium signaling to regulate neuronal gene expression. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. Nerve Growth Factor (NGF) Regulates Activity of Nuclear Factor of Activated T-cells (NFAT) in Neurons via the Phosphatidylinositol 3-Kinase (PI3K)-Akt-Glycogen Synthase Kinase 3β (GSK3β) Pathway*

    PubMed Central

    Kim, Man-Su; Shutov, Leonid P.; Gnanasekaran, Aswini; Lin, Zhihong; Rysted, Jacob E.; Ulrich, Jason D.; Usachev, Yuriy M.

    2014-01-01

    The Ca2+/calcineurin-dependent transcription factor nuclear factor of activated T-cells (NFAT) plays an important role in regulating many neuronal functions, including excitability, axonal growth, synaptogenesis, and neuronal survival. NFAT can be activated by action potential firing or depolarization that leads to Ca2+/calcineurin-dependent dephosphorylation of NFAT and its translocation to the nucleus. Recent data suggest that NFAT and NFAT-dependent functions in neurons can also be potently regulated by NGF and other neurotrophins. However, the mechanisms of NFAT regulation by neurotrophins are not well understood. Here, we show that in dorsal root ganglion sensory neurons, NGF markedly facilitates NFAT-mediated gene expression induced by mild depolarization. The effects of NGF were not associated with changes in [Ca2+]i and were independent of phospholipase C activity. Instead, the facilitatory effect of NGF depended on activation of the PI3K/Akt pathway downstream of the TrkA receptor and on inhibition of glycogen synthase kinase 3β (GSK3β), a protein kinase known to phosphorylate NFAT and promote its nuclear export. Knockdown or knockout of NFATc3 eliminated this facilitatory effect. Simultaneous monitoring of EGFP-NFATc3 nuclear translocation and [Ca2+]i changes in dorsal root ganglion neurons indicated that NGF slowed the rate of NFATc3 nuclear export but did not affect its nuclear import rate. Collectively, our data suggest that NGF facilitates depolarization-induced NFAT activation by stimulating PI3K/Akt signaling, inactivating GSK3β, and thereby slowing NFATc3 export from the nucleus. We propose that NFAT serves as an integrator of neurotrophin action and depolarization-driven calcium signaling to regulate neuronal gene expression. PMID:25231981

  13. Energy Security Strategies: An Analysis of Tanzania and Mozambique

    DTIC Science & Technology

    2016-06-01

    prioritizes domestic consumption or export of energy resources. The strategy a government chooses affects the overall energy security of that country...This thesis seeks to explain why countries pursue energy strategies that focus on domestic consumption of indigenous energy resources instead of...energy strategy that either prioritizes domestic consumption or export of energy resources. The strategy a government chooses affects the overall

  14. Small Business Export Enhancement Act of 2010

    THOMAS, 111th Congress

    Rep. Dahlkemper, Kathleen A. [D-PA-3

    2010-07-22

    House - 07/22/2010 Referred to the House Committee on Small Business. (All Actions) Notes: For further action, see H.R.5297, which became Public Law 111-240 on 9/27/2010. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. How the Dollar's Value Affects U.S. Farm Exports to Developing Countries. Foreign Agricultural Economic Report Number 237.

    ERIC Educational Resources Information Center

    Burfisher, Mary E.

    United States exports may not necessarily increase when the dollar falls on the world market. Conventional thinking is that a weaker dollar means more demand for U.S. products because they become less expensive than goods from countries with stronger currencies. However, developing countries whose export revenues are denominated in the weakening…

  16. KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency.

    PubMed

    Dhaliwal, Navroop K; Miri, Kamelia; Davidson, Scott; Tamim El Jarkass, Hala; Mitchell, Jennifer A

    2018-04-10

    Cooperative action of a transcription factor complex containing OCT4, SOX2, NANOG, and KLF4 maintains the naive pluripotent state; however, less is known about the mechanisms that disrupt this complex, initiating exit from pluripotency. We show that, as embryonic stem cells (ESCs) exit pluripotency, KLF4 protein is exported from the nucleus causing rapid decline in Nanog and Klf4 transcription; as a result, KLF4 is the first pluripotency transcription factor removed from transcription-associated complexes during differentiation. KLF4 nuclear export requires ERK activation, and phosphorylation of KLF4 by ERK initiates interaction of KLF4 with nuclear export factor XPO1, leading to KLF4 export. Mutation of the ERK phosphorylation site in KLF4 (S132) blocks KLF4 nuclear export, the decline in Nanog, Klf4, and Sox2 mRNA, and differentiation. These findings demonstrate that relocalization of KLF4 to the cytoplasm is a critical first step in exit from the naive pluripotent state and initiation of ESC differentiation. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  17. Nuclear export of the small ribosomal subunit requires the Ran–GTPase cycle and certain nucleoporins

    PubMed Central

    Moy, Terence I.; Silver, Pamela A.

    1999-01-01

    After their assembly in the nucleolus, ribosomal subunits are exported from the nucleus to the cytoplasm. After export, the 20S rRNA in the small ribosomal subunit is cleaved to yield 18S rRNA and the small 5′ ITS1 fragment. The 5′ ITS1 RNA is normally degraded by the cytoplasmic Xrn1 exonuclease, but in strains lacking XRN1, the 5′ ITS1 fragment accumulates in the cytoplasm. Using the cytoplasmic localization of the 5′ ITS1 fragment as an indicator for the export of the small ribosomal subunit, we have identified genes that are required for ribosome export. Ribosome export is dependent on the Ran–GTPase as mutations in Ran or its regulators caused 5′ ITS1 to accumulate in the nucleoplasm. Mutations in the genes encoding the nucleoporin Nup82 and in the NES exporter Xpo1/Crm1 also caused the nucleoplasmic accumulation of 5′ ITS1. Mutants in a subset of nucleoporins and in the nuclear transport factors Srp1, Kap95, Pse1, Cse1, and Mtr10 accumulate the 5′ ITS1 in the nucleolus and affect ribosome assembly. In contrast, we did not detect nuclear accumulation of 5′ ITS1 in 28 yeast strains that have mutations in other genes affecting nuclear trafficking. PMID:10465789

  18. Log export and import restrictions of the U.S. Pacific Northwest and British Columbia: past and present.

    Treesearch

    Christine L. Lane

    1998-01-01

    Export constraints affecting North American west coast logs have existed intermittently since 1831. Recent developments have tended toward tighter restrictions. National, Provincial, and State rules are described.

  19. Effects of Light Quality and Intensity on Diurnal Patterns and Rates of Photo-Assimilate Translocation and Transpiration in Tomato Leaves.

    PubMed

    Lanoue, Jason; Leonardos, Evangelos D; Grodzinski, Bernard

    2018-01-01

    Translocation of assimilates is a fundamental process involving carbon and water balance affecting source/sink relationships. Diurnal patterns of CO 2 exchange, translocation (carbon export), and transpiration of an intact tomato source leaf were determined during 14 CO 2 steady-state labeling under different wavelengths at three pre-set photosynthetic rates. Daily patterns showed that photosynthesis and export were supported by all wavelengths of light tested including orange and green. Export in the light, under all wavelengths was always higher than that at night. Export in the light varied from 65-83% of the total daily carbon fixed, depending on light intensity. Photosynthesis and export were highly correlated under all wavelengths ( r = 0.90-0.96). Export as a percentage of photosynthesis (relative export) decreased as photosynthesis increased by increasing light intensity under all wavelengths. These data indicate an upper limit for export under all spectral conditions. Interestingly, only at the medium photosynthetic rate, relative export under the blue and the orange light-emitting diodes (LEDs) were higher than under white and red-white LEDs. Stomatal conductance, transpiration rates, and water-use-efficiency showed similar daily patterns under all wavelengths. Illuminating tomato leaves with different spectral quality resulted in similar carbon export rates, but stomatal conductance and transpiration rates varied due to wavelength specific control of stomatal function. Thus, we caution that the link between transpiration and C-export may be more complex than previously thought. In summary, these data indicate that orange and green LEDs, not simply the traditionally used red and blue LEDs, should be considered and tested when designing lighting systems for optimizing source leaf strength during plant production in controlled environment systems. In addition, knowledge related to the interplay between water and C-movement within a plant and how they are affected by environmental stimuli, is needed to develop a better understanding of source/sink relationships.

  20. Effects of Light Quality and Intensity on Diurnal Patterns and Rates of Photo-Assimilate Translocation and Transpiration in Tomato Leaves

    PubMed Central

    Lanoue, Jason; Leonardos, Evangelos D.; Grodzinski, Bernard

    2018-01-01

    Translocation of assimilates is a fundamental process involving carbon and water balance affecting source/sink relationships. Diurnal patterns of CO2 exchange, translocation (carbon export), and transpiration of an intact tomato source leaf were determined during 14CO2 steady-state labeling under different wavelengths at three pre-set photosynthetic rates. Daily patterns showed that photosynthesis and export were supported by all wavelengths of light tested including orange and green. Export in the light, under all wavelengths was always higher than that at night. Export in the light varied from 65–83% of the total daily carbon fixed, depending on light intensity. Photosynthesis and export were highly correlated under all wavelengths (r = 0.90–0.96). Export as a percentage of photosynthesis (relative export) decreased as photosynthesis increased by increasing light intensity under all wavelengths. These data indicate an upper limit for export under all spectral conditions. Interestingly, only at the medium photosynthetic rate, relative export under the blue and the orange light-emitting diodes (LEDs) were higher than under white and red-white LEDs. Stomatal conductance, transpiration rates, and water-use-efficiency showed similar daily patterns under all wavelengths. Illuminating tomato leaves with different spectral quality resulted in similar carbon export rates, but stomatal conductance and transpiration rates varied due to wavelength specific control of stomatal function. Thus, we caution that the link between transpiration and C-export may be more complex than previously thought. In summary, these data indicate that orange and green LEDs, not simply the traditionally used red and blue LEDs, should be considered and tested when designing lighting systems for optimizing source leaf strength during plant production in controlled environment systems. In addition, knowledge related to the interplay between water and C-movement within a plant and how they are affected by environmental stimuli, is needed to develop a better understanding of source/sink relationships. PMID:29915612

  1. Exporting the Buyers Health Care Action Group Purchasing Model: Lessons from Other Communities

    PubMed Central

    Christianson, Jon B; Feldman, Roger

    2005-01-01

    When first implemented in Minneapolis and St. Paul, Minnesota, the Buyers Health Care Action Group's (BHCAG) purchasing approach received considerable attention as an employer-managed, consumer-driven health care model embodying many of the principles of managed competition. First BHCAG and, later, a for-profit management company attempted to export this model to other communities. Their efforts were met with resistance from local hospitals and, in many cases, apathy by employers who were expected to be supportive. This experience underscores several difficulties that appear to be inherent in implementing purchasing models based on competing care systems. It also, once again, suggests caution in drawing lessons from community-level experiments in purchasing health care. PMID:15787957

  2. The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.

    PubMed

    Sørensen, Brian B; Ehrnsberger, Hans F; Esposito, Silvia; Pfab, Alexander; Bruckmann, Astrid; Hauptmann, Judith; Meister, Gunter; Merkl, Rainer; Schubert, Thomas; Längst, Gernot; Melzer, Michael; Grasser, Marion; Grasser, Klaus D

    2017-02-01

    We identify proteins that associate with the THO core complex, and show that the TEX1 and MOS11 components functionally interact, affecting mRNA export and splicing as well as plant development. TREX (TRanscription-EXport) is a multiprotein complex that plays a central role in the coordination of synthesis, processing and nuclear export of mRNAs. Using targeted proteomics, we identified proteins that associate with the THO core complex of Arabidopsis TREX. In addition to the RNA helicase UAP56 and the mRNA export factors ALY2-4 and MOS11 we detected interactions with the mRNA export complex TREX-2 and multiple spliceosomal components. Plants defective in the THO component TEX1 or in the mRNA export factor MOS11 (orthologue of human CIP29) are mildly affected. However, tex1 mos11 double-mutant plants show marked defects in vegetative and reproductive development. In tex1 plants, the levels of tasiRNAs are reduced, while miR173 levels are decreased in mos11 mutants. In nuclei of mos11 cells increased mRNA accumulation was observed, while no mRNA export defect was detected with tex1 cells. Nevertheless, in tex1 mos11 double-mutants, the mRNA export defect was clearly enhanced relative to mos11. The subnuclear distribution of TEX1 substantially overlaps with that of splicing-related SR proteins and in tex1 plants the ratio of certain alternative splicing events is altered. Our results demonstrate that Arabidopsis TEX1 and MOS11 are involved in distinct steps of the biogenesis of mRNAs and small RNAs, and that they interact regarding some aspects, but act independently in others.

  3. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Certification Full cost. Amendment, Renewal, Other Approvals Full cost. C. Test Facility/Research Reactor... of components requiring Commission and Executive Branch review, for example, actions under 10 CFR 110... export of reactor and other components requiring Executive Branch review, for example, those actions...

  4. Small Business Export Enhancement and International Trade Act of 2009

    THOMAS, 111th Congress

    Sen. Snowe, Olympia J. [R-ME

    2009-12-09

    Senate - 09/29/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 633. (All Actions) Notes: For further action, see H.R.5297, which became Public Law 111-240 on 9/27/2010. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. Carbon Dynamics and Export from Flooded Wetlands: A Modeling Approach

    EPA Science Inventory

    Described in this article is development and validation of a process based model for carbon cycling in flooded wetlands, called WetQual-C. The model considers various biogeochemical interactions affecting C cycling, greenhouse gas emissions, organic carbon export and retention. ...

  6. An Excel‐based implementation of the spectral method of action potential alternans analysis

    PubMed Central

    Pearman, Charles M.

    2014-01-01

    Abstract Action potential (AP) alternans has been well established as a mechanism of arrhythmogenesis and sudden cardiac death. Proper interpretation of AP alternans requires a robust method of alternans quantification. Traditional methods of alternans analysis neglect higher order periodicities that may have greater pro‐arrhythmic potential than classical 2:1 alternans. The spectral method of alternans analysis, already widely used in the related study of microvolt T‐wave alternans, has also been used to study AP alternans. Software to meet the specific needs of AP alternans analysis is not currently available in the public domain. An AP analysis tool is implemented here, written in Visual Basic for Applications and using Microsoft Excel as a shell. This performs a sophisticated analysis of alternans behavior allowing reliable distinction of alternans from random fluctuations, quantification of alternans magnitude, and identification of which phases of the AP are most affected. In addition, the spectral method has been adapted to allow detection and quantification of higher order regular oscillations. Analysis of action potential morphology is also performed. A simple user interface enables easy import, analysis, and export of collated results. PMID:25501439

  7. 40 CFR 707.65 - Submission to agency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... intra-company agreement, to export the regulated chemical. (b) If the EPA action that prompts the notice... (7407M), Office of Pollution Prevention and Toxics (OPPT), Environmental Protection Agency, 1200...

  8. Export Promotion Act of 2010

    THOMAS, 111th Congress

    Sen. Klobuchar, Amy [D-MN

    2010-03-05

    Senate - 09/13/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 560. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. The Proposed U.S.-South Korea Free Trade Agreement (KORUS FTA): Provisions and Implications

    DTIC Science & Technology

    2009-04-20

    to which household purchasing power is affected by the country’s economic crisis. (See Appendix A for additional details.) Rice South Korean...have restricted U.S. fruit and vegetable exports. This new standing committee potentially could be used as the venue to attempt to resolve future SPS...to open in 2009.32 Falling imports from Korea probably were affected by a general softening of the U.S. market. U.S. exporters, including South

  10. Identification of Bicarbonate as a Trigger and Genes Involved with Extracellular DNA Export in Mycobacterial Biofilms

    PubMed Central

    Rose, Sasha J.

    2016-01-01

    ABSTRACT Extracellular DNA (eDNA) is an integral biofilm matrix component of numerous pathogens, including nontuberculous mycobacteria (NTM). Cell lysis is the source of eDNA in certain bacteria, but the source of eDNA remains unidentified for NTM, as well as for other eDNA-containing bacterial species. In this study, conditions affecting eDNA export were examined, and genes involved with the eDNA export mechanism were identified. After a method for monitoring eDNA in real time in undisturbed biofilms was established, different conditions affecting eDNA were investigated. Bicarbonate positively influenced eDNA export in a pH-independent manner in Mycobacterium avium, M. abscessus, and M. chelonae. The surface-exposed proteome of M. avium in eDNA-containing biofilms revealed abundant carbonic anhydrases. Chemical inhibition of carbonic anhydrases with ethoxzolamide significantly reduced eDNA export. An unbiased transposon mutant library screen for eDNA export in M. avium identified many severely eDNA-attenuated mutants, including one not expressing a unique FtsK/SpoIIIE-like DNA-transporting pore, two with inactivation of carbonic anhydrases, and nine with inactivation of genes belonging to a unique genomic region, as well as numerous mutants involved in metabolism and energy production. Complementation of nine mutants that included the FtsK/SpoIIIE and carbonic anhydrase significantly restored eDNA export. Interestingly, several attenuated eDNA mutants have mutations in genes encoding proteins that were found with the surface proteomics, and many more mutations are localized in operons potentially encoding surface proteins. Collectively, our data strengthen the evidence of eDNA export being an active mechanism that is activated by the bacterium responding to bicarbonate. PMID:27923918

  11. Resource nationalism in Indonesia—Effects of the 2014 mineral export ban

    USGS Publications Warehouse

    Lederer, Graham W.

    2016-09-27

    Resource nationalism encompasses a broad range of political and economic actions taken by Governments to regulate the extraction of natural resources within their borders. Policies such as increased tariffs or export restrictions can have far-reaching economic effects on international trade. As the Governments of several developing countries consider enacting nationalistic policies, an examination of the 2014 mineral export ban in Indonesia provides an instructive example of the possible impacts of resource nationalism. Significant changes in the production and trade of unprocessed (that is, ores and concentrates) and processed (that is, refined metal) aluminum, copper, and nickel before and after the export ban form the basis of this study.The U.S. Geological Survey (USGS) National Minerals Information Center (NMIC) tracks production and trade of mineral commodities between producer and consumer countries. Materials flow studies clarify the effects of an export ban on different mineral commodities by assessing changes in production, processing capacity, and trade. Using extensive data collection and monitoring procedures, the USGS NMIC investigated the effects of resource nationalism on the flow of mineral commodities from Indonesia to the global economy.

  12. 76 FR 18995 - Pesticides; Regulation to Clarify Labeling of Pesticides for Export

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... this proposed rule will not have disproportionately high and adverse human health or environmental... for all affected populations without having any disproportionately high and adverse human health or... Pesticides; Regulation to Clarify Labeling of Pesticides for Export AGENCY: Environmental Protection Agency...

  13. A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae.

    PubMed

    Feng, Wenqin; Hopper, Anita K

    2002-04-16

    Los1p, the Saccharomyces cerevisiae exportin-t homologue, binds tRNA and functions in pre-tRNA splicing and export of mature tRNA from the nucleus to the cytosol. Because LOS1 is unessential in yeast, other pathways for tRNA nuclear export must exist. We report that Cca1p, which adds nucleotides C, C, and A to the 3' end of tRNAs, is a multicopy suppressor of the defect in tRNA nuclear export caused by los1 null mutations. Mes1p, methionyl-tRNA synthetase, also suppresses the defect in nuclear export of tRNA(Met) in los1 cells. Thus, Cca1p and Mes1p seem to function in a Los1p-independent tRNA nuclear export pathway. Heterokaryon analysis indicates that Cca1p is a nucleus/cytosol-shuttling protein, providing the potential for Cca1p to function as an exporter or an adapter in this tRNA nuclear export pathway. In yeast, most mutations that affect tRNA nuclear export also cause defects in pre-tRNA splicing leading to tight coupling of the splicing and export processes. In contrast, we show that overexpressed Cca1p corrects the nuclear export, but not the pre-tRNA-splicing defects of los1Kan(r) cells, thereby uncoupling pre-tRNA splicing and tRNA nuclear export.

  14. Iran Export Embargo Act

    THOMAS, 113th Congress

    Sen. Cornyn, John [R-TX

    2013-05-21

    Senate - 05/21/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. Effect of Increased Natural Gas Exports on Domestic Energy Markets

    EIA Publications

    2012-01-01

    This report responds to an August 2011 request from the Department of Energy's Office of Fossil Energy (DOE\\/FE) for an analysis of "the impact of increased domestic natural gas demand, as exports." Appendix A provides a copy of the DOE\\/FE request letter. Specifically, DOE\\/FE asked the U.S. Energy Information Administration (EIA) to assess how specified scenarios of increased natural gas exports could affect domestic energy markets, focusing on consumption, production, and prices.

  16. A natural component from Euphorbia humifusa Willd displays novel, broad-spectrum anti-influenza activity by blocking nuclear export of viral ribonucleoprotein

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chang, So Young; Park, Ji Hoon; Kim, Young Ho

    The need to develop anti-influenza drugs with novel antiviral mechanisms is urgent because of the rapid rate of antigenic mutation and the emergence of drug-resistant viruses. We identified a novel anti-influenza molecule by screening 861 plant-derived natural components using a high-throughput image-based assay that measures inhibition of the influenza virus infection. 1,3,4,6-tetra-O-galloyl-β-D-glucopyranoside (TGBG) from Euphorbia humifusa Willd showed broad-spectrum anti-influenza activity against two seasonal influenza A strains, A/California/07/2009 (H1N1) and A/Perth/16/2009 (H3N2), and seasonal influenza B strain B/Florida/04/2006. We investigated the mode of action of TGBG using neuraminidase activity inhibition and time-of-addition assays, which evaluate the viral release and entrymore » steps, respectively. We found that TGBG exhibits a novel antiviral mechanism that differs from the FDA-approved anti-influenza drugs oseltamivir which inhibits viral release, and amantadine which inhibits viral entry. Immunofluorescence assay demonstrated that TGBG significantly inhibits nuclear export of influenza nucleoproteins (NP) during the early stages of infection causing NP to accumulate in the nucleus. In addition, influenza-induced activation of the Akt signaling pathway was suppressed by TGBG in a dose-dependent manner. These data suggest that a putative mode of action of TGBG involves inhibition of viral ribonucleoprotein (vRNP) export from the nucleus to the cytoplasm consequently disrupting the assembly of progeny virions. In summary, TGBG has potential as novel anti-influenza therapeutic with a novel mechanism of action. - Highlights: • The plant-derived natural product TGBG has broad-spectrum antiviral activity against seasonal influenza A and B viruses. • TGBG has a novel anti-viral mechanism of action that from differs from the currently available anti-influenza drugs. • TGBG hinders nuclear export of the influenza virus ribonucleoprotein (vRNP) complex. • Influenza-induced activation of the Akt signaling pathway is suppressed by TGBG treatment.« less

  17. An aminoacylation-dependent nuclear tRNA export pathway in yeast.

    PubMed

    Grosshans, H; Hurt, E; Simos, G

    2000-04-01

    Yeast Los1p, the homolog of human exportin-t, mediates nuclear export of tRNA. Using fluorescence in situ hybridization, we could show that the export of some intronless tRNA species is not detectably affected by the disruption of LOS1. To find other factors that facilitate tRNA export, we performed a suppressor screen of a synthetically lethal los1 mutant and identified the essential translation elongation factor eEF-1A. Mutations in eEF-1A impaired nuclear export of all tRNAs tested, which included both spliced and intronless species. An even stronger defect in nuclear exit of tRNA was observed under conditions that inhibited tRNA aminoacylation. In all cases, inhibition of tRNA export led to nucleolar accumulation of mature tRNAs. Our data show that tRNA aminoacylation and eEF-1A are required for efficient nuclear tRNA export in yeast and suggest coordination between the protein translation and the nuclear tRNA processing and transport machineries.

  18. An aminoacylation-dependent nuclear tRNA export pathway in yeast

    PubMed Central

    Grosshans, Helge; Hurt, Ed; Simos, George

    2000-01-01

    Yeast Los1p, the homolog of human exportin-t, mediates nuclear export of tRNA. Using fluorescence in situ hybridization, we could show that the export of some intronless tRNA species is not detectably affected by the disruption of LOS1. To find other factors that facilitate tRNA export, we performed a suppressor screen of a synthetically lethal los1 mutant and identified the essential translation elongation factor eEF-1A. Mutations in eEF-1A impaired nuclear export of all tRNAs tested, which included both spliced and intronless species. An even stronger defect in nuclear exit of tRNA was observed under conditions that inhibited tRNA aminoacylation. In all cases, inhibition of tRNA export led to nucleolar accumulation of mature tRNAs. Our data show that tRNA aminoacylation and eEF-1A are required for efficient nuclear tRNA export in yeast and suggest coordination between the protein translation and the nuclear tRNA processing and transport machineries. PMID:10766739

  19. 78 FR 51746 - Trade Barriers That U.S. Small and Medium-sized Enterprises Perceive as Affecting Exports to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... this report, an SME is defined as a firm with fewer than 500 U.S.-based employees.) The Commission is... countries; the relative effect on exports of different EU trade barriers; and ways in which SME...

  20. Export-Import Bank Termination Act

    THOMAS, 113th Congress

    Sen. Lee, Mike [R-UT

    2013-06-06

    Senate - 06/06/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  1. Export Promotion Act of 2012

    THOMAS, 112th Congress

    Sen. Pryor, Mark L. [D-AR

    2012-03-07

    Senate - 03/07/2012 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. The Proposed U.S.-South Korea Free Trade Agreement (KORUS FTA): Provisions and Implications

    DTIC Science & Technology

    2010-07-02

    resume purchases in light of the controversy that swirled around this issue, and on the extent to which household purchasing power is affected by the...U.S. fruit and vegetable exports. This new standing committee potentially could be used as the venue to attempt to resolve future SPS disputes, taking... affected by a general softening of the U.S. market. U.S. exporters, including South Korean and other foreign-owned manufacturers, shipped a total of

  3. Land use mediates riverine nitrogen export under the dominant influence of human activities

    NASA Astrophysics Data System (ADS)

    Chen, Binhui; Chang, Scott X.; Lam, Shu Kee; Erisman, Jan Willem; Gu, Baojing

    2017-09-01

    Riverine nitrogen (N) export is a crucial process that links upstream and downstream ecosystems and coastal zones. However, the driving forces of riverine N export that is closely related to water N pollution are still not well understood. In this study, we used a mass balance approach to quantify the sources of N discharge and analyzed the effect of land use composition on riverine N export, taking Zhejiang Province, China as a case study. We found that the total reactive N discharge to rivers in Zhejiang increased from 0.22 to 0.26 Tg yr-1 from 2000 to 2015. At the watershed scale, our estimate of N export agrees well with the monitored riverine N concentration in the eight major watersheds in Zhejiang. Direct discharge of domestic wastewater and effluents from wastewater treatment plants are dominant sources of riverine N export, followed by agricultural non-point sources. Although riverine N export increases with the increasing proportion of urban and agricultural land uses, we did not find any relationship between land use change and changes in riverine N export. This suggests that the dominant factor affecting riverine N export should be human activities (e.g. wastewater discharge and fertilization level), while land use only mediates riverine N export.

  4. The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell

    PubMed Central

    Tarr, Sarah J; Cryar, Adam; Thalassinos, Konstantinos; Haldar, Kasturi; Osborne, Andrew R

    2013-01-01

    The malaria parasite exports proteins across its plasma membrane and a surrounding parasitophorous vacuole membrane, into its host erythrocyte. Most exported proteins contain a Host Targeting motif (HT motif) that targets them for export. In the parasite secretory pathway, the HT motif is cleaved by the protease plasmepsin V, but the role of the newly generated N-terminal sequence in protein export is unclear. Using a model protein that is cleaved by an exogenous viral protease, we show that the new N-terminal sequence, normally generated by plasmepsin V cleavage, is sufficient to target a protein for export, and that cleavage by plasmepsin V is not coupled directly to the transfer of a protein to the next component in the export pathway. Mutation of the fourth and fifth positions of the HT motif, as well as amino acids further downstream, block or affect the efficiency of protein export indicating that this region is necessary for efficient export. We also show that the fifth position of the HT motif is important for plasmepsin V cleavage. Our results indicate that plasmepsin V cleavage is required to generate a new N-terminal sequence that is necessary and sufficient to mediate protein export by the malaria parasite. PMID:23279267

  5. 77 FR 56766 - Updated Statements of Legal Authority for the Export Administration Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... the National Emergency With Respect to the Actions of the Government of Syria. It also adds a citation... annual notice. In addition, the authority for parts 730, 736 and 746 of the EAR with respect to Syria is...--Continuation of the National Emergency With Respect to the Actions of the Government of Syria, 77 FR 27559 (May...

  6. MCM3AP in recessive Charcot-Marie-Tooth neuropathy and mild intellectual disability.

    PubMed

    Ylikallio, Emil; Woldegebriel, Rosa; Tumiati, Manuela; Isohanni, Pirjo; Ryan, Monique M; Stark, Zornitza; Walsh, Maie; Sawyer, Sarah L; Bell, Katrina M; Oshlack, Alicia; Lockhart, Paul J; Shcherbii, Mariia; Estrada-Cuzcano, Alejandro; Atkinson, Derek; Hartley, Taila; Tetreault, Martine; Cuppen, Inge; van der Pol, W Ludo; Candayan, Ayse; Battaloglu, Esra; Parman, Yesim; van Gassen, Koen L I; van den Boogaard, Marie-José H; Boycott, Kym M; Kauppi, Liisa; Jordanova, Albena; Lönnqvist, Tuula; Tyynismaa, Henna

    2017-08-01

    Defects in mRNA export from the nucleus have been linked to various neurodegenerative disorders. We report mutations in the gene MCM3AP, encoding the germinal center associated nuclear protein (GANP), in nine affected individuals from five unrelated families. The variants were associated with severe childhood onset primarily axonal (four families) or demyelinating (one family) Charcot-Marie-Tooth neuropathy. Mild to moderate intellectual disability was present in seven of nine affected individuals. The affected individuals were either compound heterozygous or homozygous for different MCM3AP variants, which were predicted to cause depletion of GANP or affect conserved amino acids with likely importance for its function. Accordingly, fibroblasts of affected individuals from one family demonstrated severe depletion of GANP. GANP has been described to function as an mRNA export factor, and to suppress TDP-43-mediated motor neuron degeneration in flies. Thus our results suggest defective mRNA export from nucleus as a potential pathogenic mechanism of axonal degeneration in these patients. The identification of MCM3AP variants in affected individuals from multiple centres establishes it as a disease gene for childhood-onset recessively inherited Charcot-Marie-Tooth neuropathy with intellectual disability. © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain.

  7. Small Business Export Opportunity Development Act of 2009

    THOMAS, 111th Congress

    Sen. Snowe, Olympia J. [R-ME

    2009-06-08

    Senate - 06/08/2009 Read twice and referred to the Committee on Small Business and Entrepreneurship. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  8. Small Business Export Growth Act of 2012

    THOMAS, 112th Congress

    Sen. Shaheen, Jeanne [D-NH

    2012-05-22

    Senate - 05/22/2012 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. Safeguard American Food Exports Act of 2013

    THOMAS, 113th Congress

    Sen. Landrieu, Mary L. [D-LA

    2013-03-12

    Senate - 03/12/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  10. Small Business Export Growth Act of 2013

    THOMAS, 113th Congress

    Sen. Shaheen, Jeanne [D-NH

    2013-06-18

    Senate - 06/18/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. American Export Promotion Act of 2013

    THOMAS, 113th Congress

    Sen. Schatz, Brian [D-HI

    2013-11-20

    Senate - 11/20/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  12. Chemical Genetics of 14-3-3 Regulation and Role in Tumor Development

    DTIC Science & Technology

    2005-11-01

    inhibitors , our group had identified a series of inhibitory compounds. When tested one of these, TK10, shows an inhibitory effect on 14-3-3 sigma nuclear...potential regulators of 14-3-3 sigma function. 5 BODY Determine the biological activity of the newly identified inhibitor of 14-3- &T nuclear export TKI0 I...have previously shown that an inhibitor of FOXOla nuclear export, TK10, inhibits the export of 14- 3-3 from the nucleus while TK10 does not affect

  13. Future riverine nitrogen export to US coastal regions: Prospects for improving water quality amid population growth.

    EPA Science Inventory

    Excess nitrogen (N) in the environment degrades ecosystems and adversely affects human health. Here we examine predictions of contemporary (2000) and future (2030) coastal N loading in the continental US by the Nutrient Export from WaterSheds (NEWS) model. Future scenarios were b...

  14. Modelling hydrological processes and dissolved organic carbon dynamics in a rehabilitated Sphagnum-dominated peatland

    NASA Astrophysics Data System (ADS)

    Bernard-Jannin, Léonard; Binet, Stéphane; Gogo, Sébastien; Leroy, Fabien; Perdereau, Laurent; Laggoun-Défarge, Fatima

    2017-04-01

    Sphagnum-dominated peatlands represent a global major stock of carbon (C). Dissolved organic carbon (DOC) exports through runoff and leaching could reduce their potential C sink function and impact downstream water quality. DOC production in peatlands is strongly controlled by the hydrology, especially water table depth (WTD). Therefore, disturbances such as drainage can lead to increase DOC exports by lowering the WTD. Hydrological restoration (e.g. rewetting) can be undertaken to restore peatland functioning with an impact on DOC exports. The objective of this study is to assess the impact of drainage and rewetting on hydrological processes and their interactions with DOC dynamics in a Sphagnum dominated peatland. A hydrological model has been applied to a drained peatland (La Guette, France) which experienced a rewetting action on February 2014 and where WTD has been recorded in four piezometers at a 15 min time step since 2009. In addition, DOC concentrations in the peatland have been measured 6 times a year since 2014. The hydrological model is a WTD dependent reservoir model composed by two reservoirs representing the micro and macro porosity of the peatland (Binet et al., 2013). A DOC production module in both reservoirs was implemented based on temperature and WTD. The model was calibrated against WTD and DOC concentrations for each piezometer. The results show that the WTD in the study area is strongly affected by local meteorological conditions that could hide the effect of the rewetting action. The preliminary results evidenced that an additional source of water, identified as groundwater supply originating from the surrounding sandy layer aquifer, is necessary to maintain the water balance, especially during wet years (NS>0.8). Finally, the DOC module was able to describe DOC concentrations measured in the peatland and could be used to assess the impact of rewetting on DOC dynamics at different locations and to identify the factors of control of DOC exports at the peatland scale before and after the restoration. This simple conceptual model requires few data to operate. Its application on different sites with contrasted settings (hydrological and climatic conditions) could provide insight on the dominant hydrological processes and their impact on DOC dynamics in peatlands. Binet S., Gogo S., Laggoun-Défarge F., A water-table dependent reservoir model to investigate the effect of drought and vascular plant invasion on peatland hydrology, Journal of Hydrology, Volume 499, 30 August 2013, Pages 132-139, ISSN 0022-1694, http://dx.doi.org/10.1016/j.jhydrol.2013.06.035.

  15. The influence of pleiotropy between viability and pollen fates on mating system evolution.

    PubMed

    Jordan, Crispin Y

    2015-02-01

    Floral displays are functionally and genetically integrated structures, so modifications to display will likely affect multiple fitness components (pleiotropy), including pollen export and self-pollination, and therefore selfing rate. Consequently, the great diversities of floral displays and of mating systems found among angiosperms have likely co-evolved. I extend previous models of mating system evolution to determine how pleiotropy that links viability (e.g., probability of survival to reproduction) and the allocation of pollen for export and selfing affects the evolution of selfing, outcrossing, and in particular, mixed mating. I show that the outcome depends on how pollen shifts from being exported, unused, or used for selfing. Furthermore, pleiotropy that affects viability can explain observations not addressed by previous theory, including the evolution of mixed mating despite high inbreeding depression in the absence of pollen-limitation. Therefore, pleiotropy may play a key role in explaining selfing rates for such species that exhibit otherwise enigmatic mating systems. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomyces cerevisiae

    PubMed Central

    Feng, Wenqin; Hopper, Anita K.

    2002-01-01

    Los1p, the Saccharomyces cerevisiae exportin-t homologue, binds tRNA and functions in pre-tRNA splicing and export of mature tRNA from the nucleus to the cytosol. Because LOS1 is unessential in yeast, other pathways for tRNA nuclear export must exist. We report that Cca1p, which adds nucleotides C, C, and A to the 3′ end of tRNAs, is a multicopy suppressor of the defect in tRNA nuclear export caused by los1 null mutations. Mes1p, methionyl-tRNA synthetase, also suppresses the defect in nuclear export of tRNAMet in los1 cells. Thus, Cca1p and Mes1p seem to function in a Los1p-independent tRNA nuclear export pathway. Heterokaryon analysis indicates that Cca1p is a nucleus/cytosol-shuttling protein, providing the potential for Cca1p to function as an exporter or an adapter in this tRNA nuclear export pathway. In yeast, most mutations that affect tRNA nuclear export also cause defects in pre-tRNA splicing leading to tight coupling of the splicing and export processes. In contrast, we show that overexpressed Cca1p corrects the nuclear export, but not the pre-tRNA-splicing defects of los1∷Kanr cells, thereby uncoupling pre-tRNA splicing and tRNA nuclear export. PMID:11959996

  17. The Bacterial Flagellar Type III Export Gate Complex Is a Dual Fuel Engine That Can Use Both H+ and Na+ for Flagellar Protein Export

    PubMed Central

    Minamino, Tohru; Morimoto, Yusuke V.; Hara, Noritaka; Aldridge, Phillip D.; Namba, Keiichi

    2016-01-01

    The bacterial flagellar type III export apparatus utilizes ATP and proton motive force (PMF) to transport flagellar proteins to the distal end of the growing flagellar structure for self-assembly. The transmembrane export gate complex is a H+–protein antiporter, of which activity is greatly augmented by an associated cytoplasmic ATPase complex. Here, we report that the export gate complex can use sodium motive force (SMF) in addition to PMF across the cytoplasmic membrane to drive protein export. Protein export was considerably reduced in the absence of the ATPase complex and a pH gradient across the membrane, but Na+ increased it dramatically. Phenamil, a blocker of Na+ translocation, inhibited protein export. Overexpression of FlhA increased the intracellular Na+ concentration in the presence of 100 mM NaCl but not in its absence, suggesting that FlhA acts as a Na+ channel. In wild-type cells, however, neither Na+ nor phenamil affected protein export, indicating that the Na+ channel activity of FlhA is suppressed by the ATPase complex. We propose that the export gate by itself is a dual fuel engine that uses both PMF and SMF for protein export and that the ATPase complex switches this dual fuel engine into a PMF-driven export machinery to become much more robust against environmental changes in external pH and Na+ concentration. PMID:26943926

  18. The Bacterial Flagellar Type III Export Gate Complex Is a Dual Fuel Engine That Can Use Both H+ and Na+ for Flagellar Protein Export.

    PubMed

    Minamino, Tohru; Morimoto, Yusuke V; Hara, Noritaka; Aldridge, Phillip D; Namba, Keiichi

    2016-03-01

    The bacterial flagellar type III export apparatus utilizes ATP and proton motive force (PMF) to transport flagellar proteins to the distal end of the growing flagellar structure for self-assembly. The transmembrane export gate complex is a H+-protein antiporter, of which activity is greatly augmented by an associated cytoplasmic ATPase complex. Here, we report that the export gate complex can use sodium motive force (SMF) in addition to PMF across the cytoplasmic membrane to drive protein export. Protein export was considerably reduced in the absence of the ATPase complex and a pH gradient across the membrane, but Na+ increased it dramatically. Phenamil, a blocker of Na+ translocation, inhibited protein export. Overexpression of FlhA increased the intracellular Na+ concentration in the presence of 100 mM NaCl but not in its absence, suggesting that FlhA acts as a Na+ channel. In wild-type cells, however, neither Na+ nor phenamil affected protein export, indicating that the Na+ channel activity of FlhA is suppressed by the ATPase complex. We propose that the export gate by itself is a dual fuel engine that uses both PMF and SMF for protein export and that the ATPase complex switches this dual fuel engine into a PMF-driven export machinery to become much more robust against environmental changes in external pH and Na+ concentration.

  19. Export-Import Bank Reauthorization Act of 2011

    THOMAS, 112th Congress

    Sen. Johnson, Tim [D-SD

    2011-09-13

    Senate - 04/17/2012 Committee on Banking, Housing, and Urban Affairs. Hearings held. Hearings printed: S.Hrg. 112-585. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  20. Increasing American Jobs Through Greater Exports to Africa Act of 2013

    THOMAS, 113th Congress

    Sen. Durbin, Richard J. [D-IL

    2013-04-11

    Senate - 09/10/2013 Placed on Senate Legislative Calendar under General Orders. Calendar No. 181. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  1. Export-Import Bank Reauthorization Act of 2014

    THOMAS, 113th Congress

    Sen. Manchin, Joe, III [D-WV

    2014-07-30

    Senate - 07/31/2014 Read the second time. Placed on Senate Legislative Calendar under General Orders. Calendar No. 502. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. Promoting American Agricultural and Medical Exports to Cuba Act of 2011

    THOMAS, 112th Congress

    Rep. Rangel, Charles B. [D-NY-15

    2011-05-12

    House - 08/25/2011 Referred to the Subcommittee on Intellectual Property, Competition and the Internet. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. Increasing American Jobs Through Greater Exports to Africa Act of 2012

    THOMAS, 112th Congress

    Sen. Durbin, Richard J. [D-IL

    2012-03-21

    Senate - 11/13/2012 Placed on Senate Legislative Calendar under General Orders. Calendar No. 536. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. 27 CFR 28.304 - Action on claim.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... appropriate TTB officer will allow or disallow claims filed under § 28.303 in accordance with existing law and... spirits as the result of any connivance, collusion, fraud, or negligence on the part of the exporter...

  5. United States-China Market Engagement and Export Promotion Act

    THOMAS, 111th Congress

    Sen. Cantwell, Maria [D-WA

    2009-08-06

    Senate - 08/06/2009 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Relating management practices and nutrient export in agricultural watersheds of the United States

    USGS Publications Warehouse

    Sprague, Lori A.; Gronberg, Jo Ann M.

    2012-01-01

    Relations between riverine export (load) of total nitrogen (N) and total phosphorus (P) from 133 large agricultural watersheds in the United States and factors affecting nutrient transport were evaluated using empirical regression models. After controlling for anthropogenic inputs and other landscape factors affecting nutrient transport-such as runoff, precipitation, slope, number of reservoirs, irrigated area, and area with subsurface tile drains-the relations between export and the area in the Conservation Reserve Program (CRP) (N) and conservation tillage (P) were positive. Additional interaction terms indicated that the relations between export and the area in conservation tillage (N) and the CRP (P) progressed from being clearly positive when soil erodibility was low or moderate, to being close to zero when soil erodibility was higher, to possibly being slightly negative only at the 90th to 95th percentile of soil erodibility values. Possible explanations for the increase in nutrient export with increased area in management practices include greater transport of soluble nutrients from areas in conservation tillage; lagged response of stream quality to implementation of management practices because of nitrogen transport in groundwater, time for vegetative cover to mature, and/or prior accumulation of P in soils; or limitations in the management practice and stream monitoring data sets. If lags are occurring, current nutrient export from agricultural watersheds may still be reflecting the influence of agricultural land-use practices that were in place before the implementation of these management practices.

  7. Arab-American trade: performance and prospects. [With oil group and non-oil group countries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Al-Bustany, B.

    1980-03-01

    Twenty Arab countries were examined by dividing them into two groups depending on the relative share of oil exports (excluding re-exports) in total exports as an annual average for 1972-1978, with a demarcation line of 50%. The oil group (OG) comprises eight countries while the non-oil group covers twelve countries. The level of Arab exports and imports increased during the period between 1972 and 1978. Oil was the dominant export but NOG countries diversified with exports of cotton and phosphate. The balance of trade of the Arab countries was positive during this period despite the persistent, and increasing, deficit ofmore » the NOG countries, Combined Arab-American trade increased substantially during the 1970's but particularly after 1974. Oil has been the major factor affecting the size and pattern of Arab-American trade. Export earnings of the OG increased while import capacity of the NOG, supported by increased financial aid received from the OG, also increased. The American balance of trade will continue to be closely linked to Arab influence. (SAC)« less

  8. [The eradication of African swine fever in Brazil, 1978-1984].

    PubMed

    Lyra, T M P

    2006-04-01

    The African swine fever episode in Brazil was due to trade and tourism between Spain, Portugal and Brazil, at a time when outbreaks were on the rise in Europe. The eradication of the disease, the slaughter of pigs, the elimination of the carcasses and the isolation of affected farms were given wide media coverage, and had a major socio-economic impact. It was forbidden to raise pigs in garbage dumps or to give them feed considered hazardous. Analyses performed in Brazil as well as national and international investigations by researchers from reference laboratories concluded that the disease had spread from Rio de Janeiro to other states, as is stated in official reports. Following emergency measures, a control programme was implemented, leading to enhanced quality in the pig farming sector. The authors describe epidemiological surveillance of African swine fever, classical swine fever and related diseases, biosafety in swine farming, and the emergency action plan comprising animal health training for veterinarians and social workers. The results of the eradication programme were excellent, despite the controversy over compulsory sacrifice in a country with serious social problems. In 2004, Brazil was the fourth largest pork producer and exporter, with an output of 2.679 million tons and exports of 508,000 tons to international markets with very high standards.

  9. Future riverine nitrogen export to US coastal regions: Prospects for improving water quality considering population growth

    EPA Science Inventory

    Excess nitrogen (N) in the environment degrades ecosystems and adversely affects human health. Here we examine predictions of contemporary (2000) and future (2030) coastal N loading in the continental US by the Nutrient Export from WaterSheds (NEWS) model. Future output is from s...

  10. 76 FR 15938 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... submit to the Office of Management and Budget (OMB) for clearance the following proposal for collection... Bureau of Industry and Security that U.S.-origin technical data will be exported only for authorized end... only be re-exported in accordance with U.S. law. Affected Public: Businesses or other for-profit...

  11. Alternative futures of dissolved inorganic nitrogen export from ...

    EPA Pesticide Factsheets

    Nitrogen (N) export from the Mississippi River Basin contributes to seasonal hypoxia in the Gulf of Mexico (GOM). We explored monthly dissolved inorganic N (DIN) export to the GOM for a historical year (2002) and two future scenarios (year 2022) by linking macroeonomic energy, agriculture market, air quality, and agriculture land management models to a DIN export model. Future scenarios considered policies aimed at encouraging bioenergy crop production and reducing atmospheric N-emissions, as well as the effect of population growth and the states’ infrastructure plans on sewage fluxes. Model-derived DIN export decreased by about 9% (from 279 to 254 kg N km−2 year−1) between 2002 and 2022 due to a 28% increase in area planted with corn, 24% improvement in crop N-recovery efficiency (NRE, to 0.52), 22% reduction in atmospheric N deposition, and 23% increase in sewage inputs. Changes in atmospheric and sewage inputs had a relatively small effect on DIN export and the effect of bioenergy crop production depended on nutrient management practices. Without improved NRE, increased production of corn would have increased DIN export by about 14% (to 289 kg N km−2 year−1) between 2002 and 2022. Model results suggest that meeting future crop demand while reducing the areal extent of hypoxia could require aggressive actions, such improving basin-level crop NRE to 0.62 or upgrading N-removal capabilities in waste water treatment plants beyond current plans. Tile-dra

  12. How can we reduce phosphorus export from lowland polders? Implications from a sensitivity analysis of a coupled model.

    PubMed

    Huang, Jiacong; Gao, Junfeng; Yan, Renhua

    2016-08-15

    Phosphorus (P) export from lowland polders has caused severe water pollution. Numerical models are an important resource that help water managers control P export. This study coupled three models, i.e., Phosphorus Dynamic model for Polders (PDP), Integrated Catchments model of Phosphorus dynamics (INCA-P) and Universal Soil Loss Equation (USLE), to describe the P dynamics in polders. Based on the coupled models and a dataset collected from Polder Jian in China, sensitivity analysis were carried out to analyze the cause-effect relationships between environmental factors and P export from Polder Jian. The sensitivity analysis results showed that P export from Polder Jian were strongly affected by air temperature, precipitation and fertilization. Proper fertilization management should be a strategic priority for reducing P export from Polder Jian. This study demonstrated the success of model coupling, and its application in investigating potential strategies to support pollution control in polder systems. Copyright © 2016. Published by Elsevier B.V.

  13. An analysis of the relationship between staff qualification and export readiness of pharmaceutical companies: the case of iran.

    PubMed

    Mohammadzadeh, Mehdi

    2012-01-01

    Export and the readiness to export constitute the first step of international marketing, which are affected by both internal and external factors of firms. One of the most important internal factors is the presence of skilled personnel. The purpose of this study was to define the relationship between staff qualification and encouragment with the readiness level of Iranian pharmacuetical firms for engagement in export marketing. The research was based on a single case study on a basket of seven leading domestic firms. For the bias reduction, questionnaires as well as interviews with managers were used. The performance of the studied factor was lower than the desired level for export readiness and there was much scope for improvement in staff qualifications to achieve such readiness. The results of this research enable small and medium-sized pharmaceutical companies to evaluate their staff qualification levels needed for export readiness and to detect their shortcomings in order to improve them.

  14. An Analysis of the Relationship Between Staff Qualification and Export Readiness of Pharmaceutical Companies: The Case of Iran

    PubMed Central

    Mohammadzadeh, Mehdi

    2012-01-01

    Export and the readiness to export constitute the first step of international marketing, which are affected by both internal and external factors of firms. One of the most important internal factors is the presence of skilled personnel. The purpose of this study was to define the relationship between staff qualification and encouragment with the readiness level of Iranian pharmacuetical firms for engagement in export marketing. The research was based on a single case study on a basket of seven leading domestic firms. For the bias reduction, questionnaires as well as interviews with managers were used. The performance of the studied factor was lower than the desired level for export readiness and there was much scope for improvement in staff qualifications to achieve such readiness. The results of this research enable small and medium-sized pharmaceutical companies to evaluate their staff qualification levels needed for export readiness and to detect their shortcomings in order to improve them. PMID:24250528

  15. The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.

    PubMed

    Port, Sarah A; Mendes, Adélia; Valkova, Christina; Spillner, Christiane; Fahrenkrog, Birthe; Kaether, Christoph; Kehlenbach, Ralph H

    2016-10-28

    Genetic rearrangements are a hallmark of several forms of leukemia and can lead to oncogenic fusion proteins. One example of an affected chromosomal region is the gene coding for Nup214, a nucleoporin that localizes to the cytoplasmic side of the nuclear pore complex (NPC). We investigated two such fusion proteins, SET-Nup214 and SQSTM1 (sequestosome)-Nup214, both containing C-terminal portions of Nup214. SET-Nup214 nuclear bodies containing the nuclear export receptor CRM1 were observed in the leukemia cell lines LOUCY and MEGAL. Overexpression of SET-Nup214 in HeLa cells leads to the formation of similar nuclear bodies that recruit CRM1, export cargo proteins, and certain nucleoporins and concomitantly affect nuclear protein and poly(A) + RNA export. SQSTM1-Nup214, although mostly cytoplasmic, also forms nuclear bodies and inhibits nuclear protein but not poly(A) + RNA export. The interaction of the fusion proteins with CRM1 is RanGTP-dependent, as shown in co-immunoprecipitation experiments and binding assays. Further analysis revealed that the Nup214 parts mediate the inhibition of nuclear export, whereas the SET or SQSTM1 part determines the localization of the fusion protein and therefore the extent of the effect. SET-Nup214 nuclear bodies are highly mobile structures, which are in equilibrium with the nucleoplasm in interphase and disassemble during mitosis or upon treatment of cells with the CRM1-inhibitor leptomycin B. Strikingly, we found that nucleoporins can be released from nuclear bodies and reintegrated into existing NPC. Our results point to nuclear bodies as a means of preventing the formation of potentially insoluble and harmful protein aggregates that also may serve as storage compartments for nuclear transport factors. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  16. The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export*

    PubMed Central

    Port, Sarah A.; Mendes, Adélia; Valkova, Christina; Spillner, Christiane; Fahrenkrog, Birthe; Kaether, Christoph; Kehlenbach, Ralph H.

    2016-01-01

    Genetic rearrangements are a hallmark of several forms of leukemia and can lead to oncogenic fusion proteins. One example of an affected chromosomal region is the gene coding for Nup214, a nucleoporin that localizes to the cytoplasmic side of the nuclear pore complex (NPC). We investigated two such fusion proteins, SET-Nup214 and SQSTM1 (sequestosome)-Nup214, both containing C-terminal portions of Nup214. SET-Nup214 nuclear bodies containing the nuclear export receptor CRM1 were observed in the leukemia cell lines LOUCY and MEGAL. Overexpression of SET-Nup214 in HeLa cells leads to the formation of similar nuclear bodies that recruit CRM1, export cargo proteins, and certain nucleoporins and concomitantly affect nuclear protein and poly(A)+ RNA export. SQSTM1-Nup214, although mostly cytoplasmic, also forms nuclear bodies and inhibits nuclear protein but not poly(A)+ RNA export. The interaction of the fusion proteins with CRM1 is RanGTP-dependent, as shown in co-immunoprecipitation experiments and binding assays. Further analysis revealed that the Nup214 parts mediate the inhibition of nuclear export, whereas the SET or SQSTM1 part determines the localization of the fusion protein and therefore the extent of the effect. SET-Nup214 nuclear bodies are highly mobile structures, which are in equilibrium with the nucleoplasm in interphase and disassemble during mitosis or upon treatment of cells with the CRM1-inhibitor leptomycin B. Strikingly, we found that nucleoporins can be released from nuclear bodies and reintegrated into existing NPC. Our results point to nuclear bodies as a means of preventing the formation of potentially insoluble and harmful protein aggregates that also may serve as storage compartments for nuclear transport factors. PMID:27613868

  17. Export Promotion Reform Act

    THOMAS, 112th Congress

    Rep. Berman, Howard L. [D-CA-28

    2012-02-15

    Senate - 06/04/2012 Received in the Senate and Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  18. Clean Energy Technology Manufacturing and Export Assistance Act of 2010

    THOMAS, 111th Congress

    Rep. Matsui, Doris O. [D-CA-5

    2010-04-27

    Senate - 08/05/2010 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  19. An Excel-based implementation of the spectral method of action potential alternans analysis.

    PubMed

    Pearman, Charles M

    2014-12-01

    Action potential (AP) alternans has been well established as a mechanism of arrhythmogenesis and sudden cardiac death. Proper interpretation of AP alternans requires a robust method of alternans quantification. Traditional methods of alternans analysis neglect higher order periodicities that may have greater pro-arrhythmic potential than classical 2:1 alternans. The spectral method of alternans analysis, already widely used in the related study of microvolt T-wave alternans, has also been used to study AP alternans. Software to meet the specific needs of AP alternans analysis is not currently available in the public domain. An AP analysis tool is implemented here, written in Visual Basic for Applications and using Microsoft Excel as a shell. This performs a sophisticated analysis of alternans behavior allowing reliable distinction of alternans from random fluctuations, quantification of alternans magnitude, and identification of which phases of the AP are most affected. In addition, the spectral method has been adapted to allow detection and quantification of higher order regular oscillations. Analysis of action potential morphology is also performed. A simple user interface enables easy import, analysis, and export of collated results. © 2014 The Author. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

  20. 76 FR 45397 - Export Inspection and Weighing Waiver for High Quality Specialty Grain Transported in Containers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... compared to an average $0.34 per metric ton for traditional grain exports. On December 13, 2005, GIPSA... mandatory inspection and weighing requirements of the USGSA that would adversely affect the marketing system... established the waiver to facilitate the marketing of high quality specialty grain by eliminating the burden...

  1. To prohibit the use, production, sale, importation, or exportation of any pesticide containing atrazine.

    THOMAS, 113th Congress

    Rep. Ellison, Keith [D-MN-5

    2013-05-17

    House - 06/03/2013 Referred to the Subcommittee on Horticulture, Research, Biotechnology, and Foreign Agriculture. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. 50 CFR 11.24 - Final administrative action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND... law judge's decision shall constitute the final administrative determination of the Secretary in the matter and shall become effective 30 calendar days from the date of the decision. ...

  3. The challenges of detecting and responding to a Lassa fever outbreak in an Ebola-affected setting.

    PubMed

    Hamblion, E L; Raftery, P; Wendland, A; Dweh, E; Williams, G S; George, R N C; Soro, L; Katawera, V; Clement, P; Gasasira, A N; Musa, E; Nagbe, T K

    2018-01-01

    Lassa fever (LF), a priority emerging pathogen likely to cause major epidemics, is endemic in much of West Africa and is difficult to distinguish from other viral hemorrhagic fevers, including Ebola virus disease (EVD). Definitive diagnosis requires laboratory confirmation, which is not widely available in affected settings. The public health action to contain a LF outbreak and the challenges encountered in an EVD-affected setting are reported herein. In February 2016, a rapid response team was deployed in Liberia in response to a cluster of LF cases. Active case finding, case investigation, contact tracing, laboratory testing, environmental investigation, risk communication, and community awareness raising were undertaken. From January to June 2016, 53 suspected LF cases were reported through the Integrated Disease Surveillance and Response system (IDSR). Fourteen cases (26%) were confirmed for LF, 14 (26%) did not have a sample tested, and 25 (47%) were classified as not a case following laboratory analysis. The case fatality rate in the confirmed cases was 29%. One case of international exportation was reported from Sweden. Difficulties were identified in timely specimen collection, packaging, and transportation (in confirmed cases, the time from sample collection to sample result ranged from 2 to 64 days) and a lack of response interventions for early cases. The delay in response to this outbreak could have been related to a number of challenges in this EVD-affected setting: a need to strengthen the IDSR system, develop preparedness plans, train rapid response teams, and build laboratory capacity. Prioritizing these actions will aid in the timely response to future outbreaks. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  4. Nutrient export from watersheds on Mt. Desert Island, maine, as a function of land use and fire history

    USGS Publications Warehouse

    Nielsen, M.G.; Kahl, J.S.

    2007-01-01

    A study of 13 small (less than 7.5 km2) watersheds on Mt. Desert Island, Maine, was conducted from January 1999 to September 2000 to determine nutrient export delivery to coastal waters around the island, and to determine whether a series of wildfires in 1947 have affected nutrient export in burned watersheds. Nutrient export (nitrate-nitrogen, total nitrogen, total phosphorus) was determined for each watershed during the study period, and was normalized by watershed area. The yield of nitrate-nitrogen (N) ranged from 10 to 140 kg/km2/year. Total N yield ranged from 42 to 250 kg/ km2/year. Total phosphorus (P) yield ranged from 1.4 to 7.9 kg/km2/year. Watersheds entirely within Acadia National Park (lacking human land-based nutrient sources) exported significantly less total N and total P than watersheds that were partly or entirely outside the park boundary. Nitrate-N export was not significantly different in these two groups of watersheds, perhaps because atmospheric deposition is a dominant source of nitrate in the study area. No relation was observed between burn history and nutrient export. Any effect of burn history may be masked by other landscape-level factors related to nutrient export. ?? Springer Science + Business Media B.V. 2007.

  5. Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export

    PubMed Central

    Neumann, Bettina; Wu, Haijia; Hackmann, Alexandra; Krebber, Heike

    2016-01-01

    The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC). Here we show that Dbp5 is also required for the nuclear export of both pre-ribosomal subunits. Yeast temperature-sensitive dbp5 mutants accumulate both ribosomal particles in their nuclei. Furthermore, Dbp5 genetically and physically interacts with known ribosomal transport factors such as Nmd3. Similar to mRNA export we show that also for ribosomal transport Dbp5 is required at the cytoplasmic side of the NPC. However, unlike its role in mRNA export, Dbp5 does not seem to undergo its ATPase cycle for this function, as ATPase-deficient dbp5 mutants that selectively inhibit mRNA export do not affect ribosomal transport. Furthermore, mutants of GLE1, the ATPase stimulating factor of Dbp5, show no major ribosomal export defects. Consequently, while Dbp5 uses its ATPase cycle to displace the export receptor Mex67 from the translocated mRNAs, Mex67 remains bound to ribosomal subunits upon transit to the cytoplasm, where it is detectable on translating ribosomes. Therefore, we propose a model, in which Dbp5 supports ribosomal transport by capturing ribosomal subunits upon their cytoplasmic appearance at the NPC, possibly by binding export factors such as Mex67. Thus, our findings reveal that although different ribonucleoparticles, mRNAs and pre-ribosomal subunits, use shared export factors, they utilize different transport mechanisms. PMID:26872259

  6. Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export.

    PubMed

    Neumann, Bettina; Wu, Haijia; Hackmann, Alexandra; Krebber, Heike

    2016-01-01

    The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC). Here we show that Dbp5 is also required for the nuclear export of both pre-ribosomal subunits. Yeast temperature-sensitive dbp5 mutants accumulate both ribosomal particles in their nuclei. Furthermore, Dbp5 genetically and physically interacts with known ribosomal transport factors such as Nmd3. Similar to mRNA export we show that also for ribosomal transport Dbp5 is required at the cytoplasmic side of the NPC. However, unlike its role in mRNA export, Dbp5 does not seem to undergo its ATPase cycle for this function, as ATPase-deficient dbp5 mutants that selectively inhibit mRNA export do not affect ribosomal transport. Furthermore, mutants of GLE1, the ATPase stimulating factor of Dbp5, show no major ribosomal export defects. Consequently, while Dbp5 uses its ATPase cycle to displace the export receptor Mex67 from the translocated mRNAs, Mex67 remains bound to ribosomal subunits upon transit to the cytoplasm, where it is detectable on translating ribosomes. Therefore, we propose a model, in which Dbp5 supports ribosomal transport by capturing ribosomal subunits upon their cytoplasmic appearance at the NPC, possibly by binding export factors such as Mex67. Thus, our findings reveal that although different ribonucleoparticles, mRNAs and pre-ribosomal subunits, use shared export factors, they utilize different transport mechanisms.

  7. REACH: impact on the US cosmetics industry?

    PubMed

    Pouillot, Anne; Polla, Barbara; Polla, Ada

    2009-03-01

    The Registration, Evaluation, Authorization and restriction of Chemicals (REACH) is a recent European regulation on chemical substances meant to protect human health and the environment. REACH imposes the "precautionary principle" where additional data and definitive action are required when uncertainty is identified. The cosmetics industry is only partially concerned by REACH: while the stages of registration and evaluation apply to cosmetics, those of authorization and restriction most likely will not, as cosmetic ingredients are already subject to regulation by various agencies and directives. REACH has potential benefits to the industry including the possibility of reassuring consumers and improving their image of chemicals and cosmetics. However, REACH also has potential disadvantages, mainly with regard to impeding innovation. The American cosmetics industry will be affected by REACH, because all US manufacturers who export substances to Europe will have to fully comply with REACH.

  8. 15 CFR 756.1 - Introduction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... following types of administrative actions are not subject to the appeals procedures described in this part... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS APPEALS § 756.1 Introduction. (a) Scope. This part 756 describes the procedures applicable to appeals from administrative...

  9. 75 FR 11842 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... the Certificate from state and federal government antitrust actions and from private treble damage... Company Affairs (``ETCA''), International Trade Administration, Department of Commerce, has received an... issued. FOR FURTHER INFORMATION CONTACT: Joseph E. Flynn, Director, Office of Competition and Economic...

  10. 75 FR 25206 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... the Certificate from state and federal government antitrust actions and from private treble damage... Company Affairs (``ETCA''), International Trade Administration, Department of Commerce, has received an... issued. FOR FURTHER INFORMATION CONTACT: Joseph E. Flynn, Director, Office of Competition and Economic...

  11. Spatial patterns of soil nitrification and nitrate export from forested headwaters in the northeastern United States

    Treesearch

    Donald S. Ross; James B. Shanley; John L. Campbell; Gregory B. Lawrence; Scott W. Bailey; Gene E. Likens; Beverley C. Wemple; I.F. Creed; F. Courchesne

    2012-01-01

    Nitrogen export from small forested watersheds is known to be affected by N deposition but with high regional variability. We studied 10 headwater catchments in the northeastern United States across a gradient of N deposition (5.4 − 9.4 kg ha−1 yr−1) to determine if soil nitrification rates...

  12. Increased nitrogen export from eastern North America to the Atlantic Ocean due to climatic and anthropogenic changes during 1901-2008

    NASA Astrophysics Data System (ADS)

    Yang, Qichun; Tian, Hanqin; Friedrichs, Marjorie A. M.; Hopkinson, Charles S.; Lu, Chaoqun; Najjar, Raymond G.

    2015-06-01

    We used a process-based land model, Dynamic Land Ecosystem Model 2.0, to examine how climatic and anthropogenic changes affected riverine fluxes of ammonium (NH4+), nitrate (NO3-), dissolved organic nitrogen (DON), and particulate organic nitrogen (PON) from eastern North America, especially the drainage areas of the Gulf of Maine (GOM), Mid-Atlantic Bight (MAB), and South Atlantic Bight (SAB) during 1901-2008. Model simulations indicated that annual fluxes of NH4+, NO3-, DON, and PON from the study area during 1980-2008 were 0.019 ± 0.003 (mean ± 1 standard deviation) Tg N yr-1, 0.18 ± 0.035 Tg N yr-1, 0.10 ± 0.016 Tg N yr-1, and 0.043 ± 0.008 Tg N yr-1, respectively. NH4+, NO3-, and DON exports increased while PON export decreased from 1901 to 2008. Nitrogen export demonstrated substantial spatial variability across the study area. Increased NH4+ export mainly occurred around major cities in the MAB. NO3- export increased in most parts of the MAB but decreased in parts of the GOM. Enhanced DON export was mainly distributed in the GOM and the SAB. PON export increased in coastal areas of the SAB and northern parts of the GOM but decreased in the Piedmont areas and the eastern parts of the MAB. Climate was the primary reason for interannual variability in nitrogen export; fertilizer use and nitrogen deposition tended to enhance the export of all nitrogen species; livestock farming and sewage discharge were also responsible for the increases in NH4+ and NO3- fluxes; and land cover change (especially reforestation of former agricultural land) reduced the export of the four nitrogen species.

  13. 76 FR 47527 - Retrospective Regulatory Review Under E.O. 13563

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Chapter VII [Docket No. 110711380... Security, Commerce. ACTION: Notice of inquiry. SUMMARY: The Bureau of Industry and Security (BIS... of portions of the Export Administration Regulations, Chemical Weapons Convention Regulations...

  14. 76 FR 18165 - Request for Public Comments Concerning Regulatory Cooperation Activities That Would Help...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... DEPARTMENT OF COMMERCE International Trade Administration Request for Public Comments Concerning Regulatory Cooperation Activities That Would Help Eliminate or Reduce Unnecessary Regulatory Divergences in North America That Disrupt U.S. Exports AGENCY: International Trade Administration, Commerce. ACTION...

  15. Identification of Bicarbonate as a Trigger and Genes Involved with Extracellular DNA Export in Mycobacterial Biofilms.

    PubMed

    Rose, Sasha J; Bermudez, Luiz E

    2016-12-06

    Extracellular DNA (eDNA) is an integral biofilm matrix component of numerous pathogens, including nontuberculous mycobacteria (NTM). Cell lysis is the source of eDNA in certain bacteria, but the source of eDNA remains unidentified for NTM, as well as for other eDNA-containing bacterial species. In this study, conditions affecting eDNA export were examined, and genes involved with the eDNA export mechanism were identified. After a method for monitoring eDNA in real time in undisturbed biofilms was established, different conditions affecting eDNA were investigated. Bicarbonate positively influenced eDNA export in a pH-independent manner in Mycobacterium avium, M. abscessus, and M. chelonae The surface-exposed proteome of M. avium in eDNA-containing biofilms revealed abundant carbonic anhydrases. Chemical inhibition of carbonic anhydrases with ethoxzolamide significantly reduced eDNA export. An unbiased transposon mutant library screen for eDNA export in M. avium identified many severely eDNA-attenuated mutants, including one not expressing a unique FtsK/SpoIIIE-like DNA-transporting pore, two with inactivation of carbonic anhydrases, and nine with inactivation of genes belonging to a unique genomic region, as well as numerous mutants involved in metabolism and energy production. Complementation of nine mutants that included the FtsK/SpoIIIE and carbonic anhydrase significantly restored eDNA export. Interestingly, several attenuated eDNA mutants have mutations in genes encoding proteins that were found with the surface proteomics, and many more mutations are localized in operons potentially encoding surface proteins. Collectively, our data strengthen the evidence of eDNA export being an active mechanism that is activated by the bacterium responding to bicarbonate. Many bacteria contain extracellular DNA (eDNA) in their biofilm matrix, as it has various biological and physical functions. We recently reported that nontuberculous mycobacteria (NTM) can contain significant quantities of eDNA in their biofilms. In some bacteria, eDNA is derived from dead cells, but that does not appear to be the case for all eDNA-containing organisms, including NTM. In this study, we found that eDNA export in NTM is conditionally dependent on the molecules to which the bacteria are exposed and that bicarbonate positively influences eDNA export. We also identified genes and proteins important for eDNA export, which begins to piece together a description of a mechanism for eDNA. Better understanding of eDNA export can give new targets for the development of antivirulence drugs, which are attractive because resistance to classical antibiotics is currently a significant problem. Copyright © 2016 Rose and Bermudez.

  16. 77 FR 29564 - Revisions to the Export Administration Regulations: Auxiliary and Miscellaneous Items That No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ...The Bureau of Industry and Security (BIS) publishes this action to propose how auxiliary and miscellaneous military equipment and related articles the President determines no longer warrant control under Category XIII (Auxiliary Military Equipment) of the United States Munitions List (USML) would be controlled under the Commerce Control List (CCL) in new Export Control Classification Numbers (ECCNs) 0A617, 0B617, 0C617, 0D617, and 0E617 as part of the proposed new ``600 series'' of ECCNs. This rule proposes also to integrate into those five new ECCNs items within the scope of Wassenaar Arrangement Munitions List (WAML) Category 17 that would be removed from the USML, or that are not specifically identified on the USML or CCL but that are currently subject to USML jurisdiction. Finally, this rule proposes to control some items now classified under ECCNs 0A018, 0A918 and 0E018 under new ECCNs 0A617 and 0E617. This action would consolidate the above- mentioned auxiliary and miscellaneous military equipment and related articles on the CCL in the proposed new ``600 series.'' This rule is one of a planned series proposing how various types of articles that the President determines, as part of the Administration's Export Control Reform Initiative, no longer warrant control on the USML under the International Traffic in Arms Regulations (ITAR), would be controlled on the CCL in accordance with the requirements of the Export Administration Regulations (EAR). This proposed rule is being published in conjunction with a proposed rule from the Department of State, Directorate of Defense Trade Controls, which would amend the list of articles controlled by USML Category XIII.

  17. Global carbon export from the terrestrial biosphere controlled by erosion.

    PubMed

    Galy, Valier; Peucker-Ehrenbrink, Bernhard; Eglinton, Timothy

    2015-05-14

    Riverine export of particulate organic carbon (POC) to the ocean affects the atmospheric carbon inventory over a broad range of timescales. On geological timescales, the balance between sequestration of POC from the terrestrial biosphere and oxidation of rock-derived (petrogenic) organic carbon sets the magnitude of the atmospheric carbon and oxygen reservoirs. Over shorter timescales, variations in the rate of exchange between carbon reservoirs, such as soils and marine sediments, also modulate atmospheric carbon dioxide levels. The respective fluxes of biospheric and petrogenic organic carbon are poorly constrained, however, and mechanisms controlling POC export have remained elusive, limiting our ability to predict POC fluxes quantitatively as a result of climatic or tectonic changes. Here we estimate biospheric and petrogenic POC fluxes for a suite of river systems representative of the natural variability in catchment properties. We show that export yields of both biospheric and petrogenic POC are positively related to the yield of suspended sediment, revealing that POC export is mostly controlled by physical erosion. Using a global compilation of gauged suspended sediment flux, we derive separate estimates of global biospheric and petrogenic POC fluxes of 157(+74)(-50) and 43(+61)(-25) megatonnes of carbon per year, respectively. We find that biospheric POC export is primarily controlled by the capacity of rivers to mobilize and transport POC, and is largely insensitive to the magnitude of terrestrial primary production. Globally, physical erosion rates affect the rate of biospheric POC burial in marine sediments more strongly than carbon sequestration through silicate weathering. We conclude that burial of biospheric POC in marine sediments becomes the dominant long-term atmospheric carbon dioxide sink under enhanced physical erosion.

  18. Role of Nuclear Pools of Aminoacyl-tRNA Synthetases in tRNA Nuclear Export

    PubMed Central

    Azad, Abul K.; Stanford, David R.; Sarkar, Srimonti; Hopper, Anita K.

    2001-01-01

    Reports of nuclear tRNA aminoacylation and its role in tRNA nuclear export (Lund and Dahlberg, 1998; Sarkar et al., 1999; Grosshans et al., 2000a) have led to the prediction that there should be nuclear pools of aminoacyl-tRNA synthetases. We report that in budding yeast there are nuclear pools of tyrosyl-tRNA synthetase, Tys1p. By sequence alignments we predicted a Tys1p nuclear localization sequence and showed it to be sufficient for nuclear location of a passenger protein. Mutations of this nuclear localization sequence in endogenous Tys1p reduce nuclear Tys1p pools, indicating that the motif is also important for nucleus location. The mutations do not significantly affect catalytic activity, but they do cause defects in export of tRNAs to the cytosol. Despite export defects, the cells are viable, indicating that nuclear tRNA aminoacylation is not required for all tRNA nuclear export paths. Because the tRNA nuclear exportin, Los1p, is also unessential, we tested whether tRNA aminoacylation and Los1p operate in alternative tRNA nuclear export paths. No genetic interactions between aminoacyl-tRNA synthetases and Los1p were detected, indicating that tRNA nuclear aminoacylation and Los1p operate in the same export pathway or there are more than two pathways for tRNA nuclear export. PMID:11359929

  19. Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export.

    PubMed

    Azad, A K; Stanford, D R; Sarkar, S; Hopper, A K

    2001-05-01

    Reports of nuclear tRNA aminoacylation and its role in tRNA nuclear export (Lund and Dahlberg, 1998; Sarkar et al., 1999; Grosshans et al., 20001) have led to the prediction that there should be nuclear pools of aminoacyl-tRNA synthetases. We report that in budding yeast there are nuclear pools of tyrosyl-tRNA synthetase, Tys1p. By sequence alignments we predicted a Tys1p nuclear localization sequence and showed it to be sufficient for nuclear location of a passenger protein. Mutations of this nuclear localization sequence in endogenous Tys1p reduce nuclear Tys1p pools, indicating that the motif is also important for nucleus location. The mutations do not significantly affect catalytic activity, but they do cause defects in export of tRNAs to the cytosol. Despite export defects, the cells are viable, indicating that nuclear tRNA aminoacylation is not required for all tRNA nuclear export paths. Because the tRNA nuclear exportin, Los1p, is also unessential, we tested whether tRNA aminoacylation and Los1p operate in alternative tRNA nuclear export paths. No genetic interactions between aminoacyl-tRNA synthetases and Los1p were detected, indicating that tRNA nuclear aminoacylation and Los1p operate in the same export pathway or there are more than two pathways for tRNA nuclear export.

  20. Magnified Sediment Export of Small Mountainous Rivers in Taiwan: Chain Reactions from Increased Rainfall Intensity under Global Warming.

    PubMed

    Lee, Tsung-Yu; Huang, Jr-Chuan; Lee, Jun-Yi; Jien, Shih-Hao; Zehetner, Franz; Kao, Shuh-Ji

    2015-01-01

    Fluvial sediment export from small mountainous rivers in Oceania has global biogeochemical significance affecting the turnover rate and export of terrestrial carbon, which might be speeding up at the recognized conditions of increased rainfall intensity. In this study, the historical runoff and sediment export from 16 major rivers in Taiwan are investigated and separated into an early stage (1970-1989) and a recent stage (1990-2010) to illustrate the changes of both runoff and sediment export. The mean daily sediment export from Taiwan Island in the recent stage significantly increased by >80% with subtle increase in daily runoff, indicating more sediment being delivered to the ocean per unit of runoff in the recent stage. The medians of the runoff depth and sediment yield extremes (99.0-99.9 percentiles) among the 16 rivers increased by 6.5%-37% and 62%-94%, respectively, reflecting the disproportionately magnified response of sediment export to the increased runoff. Taiwan is facing increasing event rainfall intensity which has resulted in chain reactions on magnified runoff and sediment export responses. As the globe is warming, rainfall extremes, which are proved to be temperature-dependent, very likely intensify runoff and trigger more sediment associated hazards. Such impacts might occur globally because significant increases of high-intensity precipitation have been observed not only in Taiwan but over most land areas of the globe.

  1. The function of the inner nuclear envelope protein SUN1 in mRNA export is regulated by phosphorylation.

    PubMed

    Li, Ping; Stumpf, Maria; Müller, Rolf; Eichinger, Ludwig; Glöckner, Gernot; Noegel, Angelika A

    2017-08-22

    SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1. It also binds to the NPC through association with the nuclear pore component Nup153, which is involved in mRNA export. The SUN1-NXF1 association is at least partly regulated by a protein kinase C (PKC) which phosphorylates serine 113 (S113) in the N-terminal domain leading to reduced interaction. The phosphorylation appears to be important for the SUN1 function in nuclear mRNA export since GFP-SUN1 carrying a S113A mutation was less efficient in restoring mRNA export after SUN1 knockdown as compared to the wild type protein. By contrast, GFP-SUN1-S113D resembling the phosphorylated state allowed very efficient export of poly(A)+RNA. Furthermore, probing a possible role of the LINC complex component Nesprin-2 in this process we observed impaired mRNA export in Nesprin-2 knockdown cells. This effect might be independent of SUN1 as expression of a GFP tagged SUN-domain deficient SUN1, which no longer can interact with Nesprin-2, did not affect mRNA export.

  2. Impacts of the Doha Round framework agreements on dairy policies.

    PubMed

    Suzuki, N; Kaiser, H M

    2005-05-01

    Dairy is highly regulated in many countries for several reasons. Perishability, seasonal imbalances, and inelastic supply and demand for milk can cause inherent market instability. Milk buyers typically have had more market power than dairy farmers. Comparative production advantages in some countries have led to regulations and policies to protect local dairy farmers by maintaining domestic prices higher than world prices. A worldwide consensus on reduction of border measures for protecting dairy products is unlikely, and dairy will probably be an exception in ongoing World Trade Organization (WTO) negotiations. Under the Doha Round framework agreements, countries may name some products such as dairy as "sensitive," thereby excluding them from further reforms. However, new Doha Round framework agreements depart from the current WTO rule and call for product-specific spending caps. Such caps will greatly affect the dairy sector because dairy accounts for much of the aggregate measure of support (AMS) in several countries, including the United States and Canada. Also, the amounts of dairy AMS in several countries may be recalculated relative to an international reference price. In addition, all export subsidies are targeted for elimination in the Doha Round, including export credit programs and state trading enterprises, which will limit options for disposing of surplus dairy products in foreign markets. Currently, with higher domestic prices, measures for cutting or disposing of surpluses have been used in many countries. Supply control, which is not regulated by WTO rules, remains as an option. Although explicit export subsidies are restricted by WTO rules, many countries use esoteric measures to promote dairy exports. If countries agree to eliminate "consumer financed" export subsidies using a theoretical definition and measurements proposed herein as Export Subsidy Equivalents (ESE), dairy exports in many countries may be affected. Although domestic supports and export subsidies will be reduced in the Doha Round, possible exclusion of "sensitive" products from tariff reduction will help some countries' dairy sectors survive after those final agreements. A key concern for those countries will be the simultaneous restriction of surplus-disposing measures. With fewer marketing options for surpluses, countries that continue border protection and high internal prices will likely be forced to use domestic supply control programs in the future.

  3. Life cycle greenhouse gas emissions from U.S. liquefied natural gas exports: implications for end uses.

    PubMed

    Abrahams, Leslie S; Samaras, Constantine; Griffin, W Michael; Matthews, H Scott

    2015-03-03

    This study analyzes how incremental U.S. liquefied natural gas (LNG) exports affect global greenhouse gas (GHG) emissions. We find that exported U.S. LNG has mean precombustion emissions of 37 g CO2-equiv/MJ when regasified in Europe and Asia. Shipping emissions of LNG exported from U.S. ports to Asian and European markets account for only 3.5-5.5% of precombustion life cycle emissions, hence shipping distance is not a major driver of GHGs. A scenario-based analysis addressing how potential end uses (electricity and industrial heating) and displacement of existing fuels (coal and Russian natural gas) affect GHG emissions shows the mean emissions for electricity generation using U.S. exported LNG were 655 g CO2-equiv/kWh (with a 90% confidence interval of 562-770), an 11% increase over U.S. natural gas electricity generation. Mean emissions from industrial heating were 104 g CO2-equiv/MJ (90% CI: 87-123). By displacing coal, LNG saves 550 g CO2-equiv per kWh of electricity and 20 g per MJ of heat. LNG saves GHGs under upstream fugitive emissions rates up to 9% and 5% for electricity and heating, respectively. GHG reductions were found if Russian pipeline natural gas was displaced for electricity and heating use regardless of GWP, as long as U.S. fugitive emission rates remain below the estimated 5-7% rate of Russian gas. However, from a country specific carbon accounting perspective, there is an imbalance in accrued social costs and benefits. Assuming a mean social cost of carbon of $49/metric ton, mean global savings from U.S. LNG displacement of coal for electricity generation are $1.50 per thousand cubic feet (Mcf) of gaseous natural gas exported as LNG ($.028/kWh). Conversely, the U.S. carbon cost of exporting the LNG is $1.80/Mcf ($.013/kWh), or $0.50-$5.50/Mcf across the range of potential discount rates. This spatial shift in embodied carbon emissions is important to consider in national interest estimates for LNG exports.

  4. The Return of the Freudian Couch®: Managing Affectivity through Technologies of Comfort

    ERIC Educational Resources Information Center

    Juelskjaer, Malou; Staunaes, Dorthe; Ratner, Helene

    2013-01-01

    This article explores how the affective "set-up" of Freud's legendary couch has been exported into modern education relations. The so-called psy-sciences from pedagogy, psychology, and psychiatry have informed self-management in school. Managing self-management has a material-affective dimension. Through affective encounters with the…

  5. Communication imperialism and dependency: a conceptual clarification.

    PubMed

    Lee, P S

    1988-01-01

    Communications imperialism has to do with the domination of a country's media activities by another. The ownership, structure, distribution or content of the media in 1 country are affected by pressures from media interests of another country or group out of proportion with those of that country. To determine if this is happening we should consider the country's policies, the private sector;s efforts to export communications elements, and actions of the dominant country against the dominated. The 4 aspects of international media in this situation are television program exportation, foreign ownership and control of media distribution, the infringement of capital opinions on other societies, and the transfer of commercialism and broadcasting norms. In addition to the software and hardware and the other forms of communication such as satellites, computers, and transportation of the mass media, there are the cultural effects on the developing countries. In the case of involuntary of voluntary dependency of the recipient country, the effect of the unbalanced international communication can be harmful or beneficial. Communication dependency may not be harmful to the culture of the recipient country. In determining the theory of unbalanced international communications 3 factors should be considered. There are: the role of the interacting countries, the nature of the dependency of the recipient country, and the beneficial or harmful effect of unbalanced communication pattern on that country.

  6. 76 FR 11760 - Request for Public Comments Concerning Regulatory Cooperation Activities That Would Help...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... DEPARTMENT OF COMMERCE International Trade Administration Request for Public Comments Concerning... North America That Disrupt U.S. Exports AGENCY: International Trade Administration, Commerce. ACTION... Mexico. With this Notice, the Commerce Department, on behalf of the Administration, is seeking public...

  7. 77 FR 51097 - Notice of Action Subject to Intergovernmental Review Under Executive Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ... an SBDC. SBDCs offer training, counseling and other business development assistance to small... counseling to existing and prospective small business owners in management, marketing, finance, operations... particular attention to SBA's priority and special emphasis groups, including veterans, women, exporters, the...

  8. 75 FR 60457 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open... Avenue, NW., Washington, DC 20571. Open Agenda Item: PEFCO Secured Note Issues Resolutions. Public Participation: The meeting will be open to public participation for Item No. 1 only. Further Information: For...

  9. 21 CFR 1309.41 - Administrative review generally.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

  10. 21 CFR 1309.41 - Administrative review generally.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

  11. 21 CFR 1309.41 - Administrative review generally.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

  12. 21 CFR 1309.41 - Administrative review generally.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

  13. 21 CFR 1309.41 - Administrative review generally.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

  14. Poles apart: does the export of mental health expertise from the Global North to the Global South represent a neutral relocation of knowledge and practice?

    PubMed

    Cox, Nigel; Webb, Lucy

    2015-06-01

    The World Health Organization's Mental Health Action Plan 2013-2020 identifies actions for all member states to alleviate the global burden of mental ill health, including an obligation for mental healthcare to be delivered in a 'culturally appropriate' manner. In this article we argue that such a requirement is problematic, not least because such pronouncements remain framed by the normative prepositions of Western medical and psychological practice and their associated ethical, legal and institutional standpoints. As such, when striving to export Western mental health expertise, different paradigms for evidence will be necessary to deliver locally meaningful interventions to low and middle income countries. Our discussion highlights a number of philosophical concerns regarding methodologies for future research practice, including those relating to representation and exclusion in the guise of epistemic injury, presumptive methodologies arising from Western notions of selfhood, and related ethical issues. © 2015 Foundation for the Sociology of Health & Illness.

  15. Banning Asbestos in New Zealand, 1936–2016, an 80-Year Long Saga

    PubMed Central

    Glass, William Ivan; Armstrong, Rob; Chen, Grace

    2017-01-01

    The banning by the New Zealand Government of the import and export of asbestos-containing products resulted from the interplay of a number of factors. At a personal level, there were the actions of the asbestos sufferers, their families and support groups. At the political level, there were the activities of progressive trade union groups representing the hazardous trades, such as labourers, construction workers and demolition workers, and at a Government level, there was a positive response to these public health pressures. The Prohibition Order 2016 concerning Imports and Exports (asbestos-containing products) was the outcome of this 80-year long saga. PMID:29186845

  16. Banning Asbestos in New Zealand, 1936-2016, an 80-Year Long Saga.

    PubMed

    Glass, William Ivan; Armstrong, Rob; Chen, Grace

    2017-11-25

    The banning by the New Zealand Government of the import and export of asbestos-containing products resulted from the interplay of a number of factors. At a personal level, there were the actions of the asbestos sufferers, their families and support groups. At the political level, there were the activities of progressive trade union groups representing the hazardous trades, such as labourers, construction workers and demolition workers, and at a Government level, there was a positive response to these public health pressures. The Prohibition Order 2016 concerning Imports and Exports (asbestos-containing products) was the outcome of this 80-year long saga.

  17. 77 FR 22559 - Proposed Information Collection; Comment Request; Chemical Weapons Convention Provisions of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Proposed Information Collection; Comment Request; Chemical Weapons Convention Provisions of the Export Administration Regulations AGENCY: Bureau of Industry and Security, Commerce. ACTION: Notice. SUMMARY: The Department of Commerce, as part of its...

  18. 19 CFR 191.166 - Destruction of merchandise.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... THE TREASURY (CONTINUED) DRAWBACK Distilled Spirits, Wines, or Beer Which Are Unmerchantable or Do Not... drawback claimant who proposes to destroy rather than export the distilled spirits, wine, or beer shall state that fact on Customs Form 7551. (b) Action by Customs. Distilled spirits, wine, or beer returned...

  19. 19 CFR 191.166 - Destruction of merchandise.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... THE TREASURY (CONTINUED) DRAWBACK Distilled Spirits, Wines, or Beer Which Are Unmerchantable or Do Not... drawback claimant who proposes to destroy rather than export the distilled spirits, wine, or beer shall state that fact on Customs Form 7551. (b) Action by Customs. Distilled spirits, wine, or beer returned...

  20. 22 CFR 126.7 - Denial, revocation, suspension or amendment of licenses and other approvals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... without prior notice whenever: (1) The Department of State deems such action to be in furtherance of world... or end-user of any item to be exported. [58 FR 39312, July 22, 1993, as amended at 71 FR 20546, Apr...

  1. 22 CFR 126.7 - Denial, revocation, suspension, or amendment of licenses and other approvals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... without prior notice whenever: (1) The Department of State deems such action to be in furtherance of world...) Any consignee or end-user of any item to be exported. [58 FR 39312, July 22, 1993, as amended at 71 FR...

  2. 22 CFR 126.7 - Denial, revocation, suspension, or amendment of licenses and other approvals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... without prior notice whenever: (1) The Department of State deems such action to be in furtherance of world...) Any consignee or end-user of any item to be exported. [58 FR 39312, July 22, 1993, as amended at 71 FR...

  3. 22 CFR 126.7 - Denial, revocation, suspension or amendment of licenses and other approvals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... without prior notice whenever: (1) The Department of State deems such action to be in furtherance of world... or end-user of any item to be exported. [58 FR 39312, July 22, 1993, as amended at 71 FR 20546, Apr...

  4. 75 FR 40855 - Notice of Action Subject to Intergovernmental Review Under Executive Order 12372

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... training, counseling and other business development assistance to small businesses. Each SBDC provides... objectives. Services include training and counseling to existing and prospective small business owners in... groups, including veterans, women, exporters, the disabled, and minorities. SBDC Program Requirements An...

  5. 75 FR 11534 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. Open Agenda Items: Item No. 1 Revision of Eximbank's Environmental Procedures and.... Public Participation: The meeting will be open to public observation for Items No. 1 & 2 only. For...

  6. 76 FR 77229 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. OPEN AGENDA ITEM: Item No. 1: Ex-Im Bank Advisory Committee for 2012 (Additional Members). PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only...

  7. 78 FR 38031 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    ... EXPORT-IMPORT BANK Sunshine Act Meetings ACTION: Notice of a Partially Open Meeting of the Board...., Washington, DC 20571. OPEN AGENDA ITEMS: Item No. 1: Ex-Im Bank's Environmental Procedures and Guidelines. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FURTHER...

  8. 78 FR 36779 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... EXPORT-IMPORT BANK Sunshine Act Meeting ACTION: Notice of a Partially Open Meeting of the Board of.... OPEN AGENDA ITEMS: Item No. 1: Ex-Im Bank's Environmental Procedures and Guidelines. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FOR FURTHER INFORMATION...

  9. 76 FR 70110 - Proposed Information Collection; Comment Request; Miscellaneous Short Supply Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Request; Miscellaneous Short Supply Activities AGENCY: Bureau of Industry and Security, Commerce. ACTION... of two rarely used short supply activities: ``Registration of U.S. Agricultural Commodities for Exemption from Short Supply Limitations on Export'' (USAG), and ``Petitions for the Imposition of Monitoring...

  10. 75 FR 11841 - Proposed Information Collection; Comment Request; Short Supply Regulations, Petroleum (Crude Oil)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Proposed Information Collection; Comment Request; Short Supply Regulations, Petroleum (Crude Oil) AGENCY: Bureau of Industry and Security. ACTION... supporting documentation for license applications to export petroleum (crude oil) and is used by licensing...

  11. 75 FR 78980 - Application to Export Electric Energy; Direct Energy Marketing, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Marketing, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: Direct Energy Marketing, Inc. (DEMI) has applied to renew its authority to transmit..., Federal power marketing agencies, and other entities within the United States. The existing international...

  12. 75 FR 38514 - Application to Export Electric Energy; Brookfield Energy Marketing LP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... Energy Marketing LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing LP (BEM LP) has applied for authority to transmit electric... surplus energy purchased from electric utilities, Federal power marketing agencies and other entities...

  13. 75 FR 80482 - Application To Export Electric Energy; TransCanada Power Marketing Ltd.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... Power Marketing Ltd. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: TransCanada Power Marketing Ltd. (TCPM) has applied to renew its authority... marketing agencies, and other entities within the United States. The existing international transmission...

  14. 75 FR 12737 - Applications To Export Electric Energy; Noble Energy Marketing and Trade Corp.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ...; Noble Energy Marketing and Trade Corp. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Under two separate applications, Noble Energy Marketing... power marketing agencies, and other entities within the United States. NEMT has requested electricity...

  15. 77 FR 20375 - Application to Export Electric Energy; Rainbow Energy Marketing Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... Energy Marketing Corporation AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Rainbow Energy Marketing Corporation (Rainbow) has applied to renew its... Energy Marketing Corporation, Kirkwood Office Tower, 919 South 7th Street, Suite 405, Bismarck, ND 58504...

  16. 78 FR 16530 - Fresh Tomatoes From Mexico; Suspension of Antidumping Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-747 (Third Review)] Fresh Tomatoes From.... ACTION: Notice. SUMMARY: The subject five-year review was instituted on December 3, 2012, to determine... growers/exporters accounting for a significant percentage of all fresh tomatoes imported into the United...

  17. CopZ from Bacillus subtilis interacts in vivo with a copper exporting CPx-type ATPase CopA.

    PubMed

    Radford, David S; Kihlken, Margaret A; Borrelly, Gilles P M; Harwood, Colin R; Le Brun, Nick E; Cavet, Jennifer S

    2003-03-14

    The structure of the hypothetical copper-metallochaperone CopZ from Bacillus subtilis and its predicted partner CopA have been studied but their respective contributions to copper export, -import, -sequestration and -supply are unknown. DeltacopA was hypersensitive to copper and contained more copper atoms cell(-1) than wild-type. Expression from the copA operator-promoter increased in elevated copper (not other metals), consistent with a role in copper export. A bacterial two-hybrid assay revealed in vivo interaction between CopZ and the N-terminal domain of CopA but not that of a related transporter, YvgW, involved in cadmium-resistance. Activity of copper-requiring cytochrome caa(3) oxidase was retained in deltacopZ and deltacopA. DeltacopZ was only slightly copper-hypersensitive but deltacopZ/deltacopA was more sensitive than deltacopA, implying some action of CopZ that is independent of CopA. Significantly, deltacopZ contained fewer copper atoms cell(-1) than wild-type under these conditions. CopZ makes a net contribution to copper sequestration and/or recycling exceeding any donation to CopA for export.

  18. Magnified Sediment Export of Small Mountainous Rivers in Taiwan: Chain Reactions from Increased Rainfall Intensity under Global Warming

    PubMed Central

    Lee, Tsung-Yu; Huang, Jr-Chuan; Lee, Jun-Yi; Jien, Shih-Hao; Zehetner, Franz; Kao, Shuh-Ji

    2015-01-01

    Fluvial sediment export from small mountainous rivers in Oceania has global biogeochemical significance affecting the turnover rate and export of terrestrial carbon, which might be speeding up at the recognized conditions of increased rainfall intensity. In this study, the historical runoff and sediment export from 16 major rivers in Taiwan are investigated and separated into an early stage (1970–1989) and a recent stage (1990–2010) to illustrate the changes of both runoff and sediment export. The mean daily sediment export from Taiwan Island in the recent stage significantly increased by >80% with subtle increase in daily runoff, indicating more sediment being delivered to the ocean per unit of runoff in the recent stage. The medians of the runoff depth and sediment yield extremes (99.0–99.9 percentiles) among the 16 rivers increased by 6.5%-37% and 62%-94%, respectively, reflecting the disproportionately magnified response of sediment export to the increased runoff. Taiwan is facing increasing event rainfall intensity which has resulted in chain reactions on magnified runoff and sediment export responses. As the globe is warming, rainfall extremes, which are proved to be temperature-dependent, very likely intensify runoff and trigger more sediment associated hazards. Such impacts might occur globally because significant increases of high-intensity precipitation have been observed not only in Taiwan but over most land areas of the globe. PMID:26372356

  19. 75 FR 29680 - Importation of Mexican Hass Avocados; Additional Shipping Options

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... Avocados; Additional Shipping Options AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... originating in Michoacan, Mexico, into the United States by adding the option to ship avocados to the United... additional options for shipping Hass avocados from Mexico to the United States and allow Mexican exporters to...

  20. 77 FR 38582 - Proposed Information Collection; Comment Request; Domestic Client Life-Cycle Multi-Purpose Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Request; Domestic Client Life-Cycle Multi-Purpose Forms AGENCY: International Trade Administration. ACTION... life-cycle with CS. CS is mandated by Congress to help U.S. organizations, particularly small and... Client Life-cycle Multi-Purpose Forms, previously titled Export Information Services Order Forms, are...

  1. 78 FR 37778 - Notice of Request for Extension of Approval of an Information Collection; Export Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2013-0040... Animal Products AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of approval... Act of 1995, this notice announces the Animal and Plant Health Inspection Service's intention to...

  2. 75 FR 15673 - Notice of Request for Extension of Approval of an Information Collection; Export Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2010-0014... Animal Products AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of approval... Act of 1995, this notice announces the Animal and Plant Health Inspection Service's intention to...

  3. 75 FR 8102 - Proposed Information Collection; OMB Control Number 1018-0137; Applications for Single Use...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... Registration of Production Facilities (CITES) AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice... to the import or export of CITES-listed species, the Management Authority and Scientific Authority... and U.S. Scientific Authority for CITES. The Secretary delegated these authorities to the Fish and...

  4. 77 FR 55201 - Notice of Orders Granting Applications to Import and Export Natural Gas and Vacating Prior...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... Renewables, LLC AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives notice that during July 2012....fossil.energy.gov/programs/ gasregulation/authorizations/ [[Page 55202

  5. 14 CFR 1216.321 - Environmental effects abroad of major Federal actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... participating with or not otherwise involved in the NASA activity; (3) The export of products or facilities... for Management will provide additional guidance regarding the types of chemical, physical, and biological agents involved. (4) A physical project which, in the U.S., would be prohibited or strictly...

  6. 75 FR 81152 - Export Control Modernization: Strategic Trade Authorization License Exception

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Parts 732, 738, 740, 743, 758, and... Authorization License Exception AGENCY: Bureau of Industry and Security, Commerce. ACTION: Proposed rule..., Bureau of Industry and Security, Room 2705, U.S. Department of Commerce, Washington, DC 20230. Please...

  7. 75 FR 75453 - Proposed Information Collection; Comment Request; Technical Data Letter of Explanation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-03

    ... Request; Technical Data Letter of Explanation AGENCY: Bureau of Industry and Security. ACTION: Notice....gov . SUPPLEMENTARY INFORMATION: I. Abstract These technical data letters of explanation will assure the Bureau of Industry and Security that U.S.-origin technical data will be exported only for...

  8. 78 FR 11633 - Application To Export Electric Energy; ConocoPhillips Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ...Phillips Company AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of Application. SUMMARY: ConocoPhillips Company (CoP) has applied to renew its authority to transmit electric... Delivery and Energy Reliability, Mail Code: OE-20, U.S. Department of Energy, 1000 Independence Avenue SW...

  9. 75 FR 22579 - Application To Export Electric Energy; Morgan Stanley Capital Group Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... Stanley Capital Group Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION...: Office of Electricity Delivery and Energy Reliability, Mail Code: OE-20, U.S. Department of Energy, 1000.... Zabrocki, Morgan Stanley & Co. Incorporated, 2000 Westchester Ave., Purchase, NY 10577 and Daniel E. Frank...

  10. 76 FR 67430 - Application To Export Electric Energy; Tenaska Power Services Co.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... Services Co. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Tenaska Power Services Co. (Tenaska) has applied to renew its authority to transmit... of Electricity Delivery and Energy Reliability, Mail Code: OE-20, U.S. Department of Energy, 1000...

  11. 12 CFR 411.410 - Enforcement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Enforcement. 411.410 Section 411.410 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES NEW RESTRICTIONS ON LOBBYING Penalties and Enforcement § 411.410 Enforcement. The head of each agency shall take such actions as are necessary to ensure that...

  12. 10 CFR 110.130 - Initiation of rulemaking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Initiation of rulemaking. 110.130 Section 110.130 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND MATERIAL Rulemaking § 110.130 Initiation of rulemaking. The Commission may initiate action to amend the regulations in this...

  13. 78 FR 62500 - Schedules of Controlled Substances: Placement of Perampanel into Schedule III

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... of the Controlled Substances Act (CSA). This proposed action is based on a recommendation from the... (manufacture, distribute, dispense, import, export, engage in research, conduct instructional activities, and..., scientific, research, and industrial needs of the United States. Controlled substances have the potential for...

  14. 78 FR 71022 - Defense Trade Advisory Group; Notice of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... DEPARTMENT OF STATE [Public Notice 8534] Defense Trade Advisory Group; Notice of Open Meeting AGENCY: Department of State. ACTION: Notice of meeting. SUMMARY: The Defense Trade Advisory Group (DTAG... consequences of the Export Control Reform Initiatives on industry and provide recommendation on how to overcome...

  15. 76 FR 41497 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. OPEN AGENDA ITEMS: Item No. 1: Resolution honoring the service of Ex-Im Bank's outgoing Director, Diane Farrell. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No...

  16. 78 FR 57632 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... EXPORT-IMPORT BANK Sunshine Act Meeting ACTION: Notice of a Partially Open Meeting of the Board of... 20571. OPEN AGENDA ITEMS: Item No. 1: PEFCO Secured Notes Resolutions for FY 2014. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FURTHER INFORMATION: Members of...

  17. 78 FR 40475 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... EXPORT-IMPORT BANK Sunshine Act Meeting ACTION: Notice of a Partially Open Meeting of the Board of.... OPEN AGENDA ITEMS: Item No. 1: Resolution presented to a member of the Board of Directors upon his resignation. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FOR...

  18. 75 FR 73082 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. Open Agenda Item: Item No. 1: Ex-Im Bank Advisory Committee for 2011. Public Participation: The meeting will be open to public observation for Item No. 1 only. FURTHER INFORMATION: For...

  19. 76 FR 10898 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. OPEN AGENDA ITEMS: Item No. 1: Ex-Im Bank Sub-Saharan Africa Advisory Committee for 2011. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FURTHER...

  20. 75 FR 6661 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. Open Agenda Items: Item No. 1: Ex-Im Bank Sub-Saharan Africa Advisory Committee for 2010. Public Participation: The meeting will be open to public observation for Item No. 1 only. Further...

  1. 77 FR 40612 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open...., Washington, DC 20571. OPEN AGENDA ITEMS: Item No. 1: Ex-Im Bank Sub-Saharan Africa Advisory Committee for 2012. PUBLIC PARTICIPATION: The meeting will be open to public observation for Item No. 1 only. FURTHER...

  2. 76 FR 73632 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a Partially Open..., Washington, DC 20571. Open Agenda Item: Item No. 1: Ex-Im Bank Advisory Committee for 2011. Public Participation: The meeting will be open to public observation for Item No. 1 only. FOR FURTHER INFORMATION...

  3. 78 FR 72883 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of an Open Meeting of...., Washington, DC 20571. OPEN AGENDA ITEMS: Item No. 1 Ex-Im Bank Advisory Committee for 2014 (New Members) Item... open to public observation for Items No. 1 & 2 only. FURTHER INFORMATION: Members of the public who...

  4. 75 FR 8065 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting ACTION: Notice of a partially open...., Washington, DC 20571. Open Agenda Items: Item No. 1: Ex-Im Bank Sub-Saharan Africa Advisory Committee for 2010. Public Participation: The meeting will be open to public observation for Item No. 1 only. Further...

  5. 75 FR 17052 - Issuance of Electronic Documents and Related Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... BIS to eliminate the paper versions of most export and reexport licenses, notices of denial of license applications, notices of return of a license application without action, notices of results of classification requests, License Exception AGR notification results, and encryption review request results. This rule also...

  6. 77 FR 39689 - Application To Export Electric Energy; IPR-GDF SUEZ Energy Marketing North America, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Energy Marketing North America, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: IPR-GDF SUEZ Energy Marketing North America, Inc. (GSEMNA) has... Mexico would be surplus energy purchased from electric utilities, Federal power marketing agencies, and...

  7. A resolution supporting increased market access for exports of United States beef and beef products.

    THOMAS, 111th Congress

    Sen. Baucus, Max [D-MT

    2010-05-27

    Senate - 05/27/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  8. 75 FR 75994 - Application To Export Electric Energy; NRG Power Marketing LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... Marketing LLC AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: NRG Power Marketing LLC (NRGPML) has applied to renew its authority to transmit electric... to Canada would be surplus energy purchased from electric utilities, Federal power marketing agencies...

  9. 75 FR 57911 - Application To Export Electric Energy; GDF SUEZ Energy Marketing NA, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... Marketing NA, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: GDF SUEZ Energy Marketing NA, Inc. (GSEMNA) has applied for authority to transmit... purchased from electric utilities, Federal power marketing agencies and other entities within the United...

  10. 77 FR 43598 - Agency Information Collection Activities: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ...: Comment Request AGENCY: Export-Import Bank of the U.S. ACTION: Submission for OMB review and comments... previous calendar year with an electronic invitation to participate in the online survey. The proposed... of Review: Renewal. Need and Use: This information will be used to fulfill the statutory mandate...

  11. 78 FR 76859 - Agency Information Collection Activities; Proposed Collection; Comments Requested: Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... DEPARTMENT OF JUSTICE Bureau of Alcohol, Tobacco, Firearms and Explosives [OMB Number 1140-0017] Agency Information Collection Activities; Proposed Collection; Comments Requested: Annual Firearms Manufacturing and Exportation Report Under United States Code, Firearms ACTION: 60-Day notice. The Department of Justice (DOJ), Bureau of Alcohol,...

  12. 76 FR 14993 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Controlled...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... Declaration-- DEA Form 236 ACTION: 60-Day Notice of Information Collection Under Review. The Department of Justice (DOJ), Drug Enforcement Administration (DEA), will be submitting the following information... Substances Import/ Export Declaration--DEA Form 236. (3) Agency form number, if any, and the applicable...

  13. 77 FR 47666 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Import/Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... II Chemicals; DEA Forms 486 and 486A ACTION: 60-Day Notice of Information Collection Under Review. The Department of Justice (DOJ), Drug Enforcement Administration (DEA), will be submitting the... Justice sponsoring the collection: Form Number: DEA Forms 486 and 486A. Component: Office of Diversion...

  14. 76 FR 27352 - Agency Information Collection Activities; Proposed Collection; Comments Requested; Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Substances/Export Controlled Substances for Reexport DEA Forms 161 and 161r ACTION: 30-Day Notice of Information Collection Under Review. The Department of Justice (DOJ), Drug Enforcement Administration (DEA... sponsoring the collection: Form number: DEA Forms 161 and 161r. Component: Office of Diversion Control, Drug...

  15. The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.

    PubMed

    Aleidi, Shereen M; Yang, Alryel; Sharpe, Laura J; Rao, Geetha; Cochran, Blake J; Rye, Kerry-Anne; Kockx, Maaike; Brown, Andrew J; Gelissen, Ingrid C

    2018-04-01

    The ABC lipid transporters, ABCA1 and ABCG1, are essential for maintaining lipid homeostasis in cells such as macrophages by exporting excess cholesterol to extracellular acceptors. These transporters are highly regulated at the post-translational level, including protein ubiquitination. Our aim was to investigate the role of the E3 ubiquitin ligase HECTD1, recently identified as associated with ABCG1, on ABCG1 and ABCA1 protein levels and cholesterol export function. Here, we show that HECTD1 protein is widely expressed in a range of human and murine primary cells and cell lines, including macrophages, neuronal cells and insulin secreting β-cells. siRNA knockdown of HECTD1 unexpectedly decreased overexpressed ABCG1 protein levels and cell growth, but increased native ABCA1 protein in CHO-K1 cells. Knockdown of HECTD1 in unloaded THP-1 macrophages did not affect ABCG1 but significantly increased ABCA1 protein levels, in wild-type as well as THP-1 cells that do not express ABCG1. Cholesterol export from macrophages to apoA-I over time was increased after knockdown of HECTD1, however these effects were not sustained in cholesterol-loaded cells. In conclusion, we have identified a new candidate, the E3 ubiquitin ligase HECTD1, that may be involved in the regulation of ABCA1-mediated cholesterol export from unloaded macrophages to apoA-I. The exact mechanism by which this ligase affects this pathway remains to be elucidated. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Roles of export genes cgmA and lysE for the production of L-arginine and L-citrulline by Corynebacterium glutamicum.

    PubMed

    Lubitz, Dorit; Jorge, João M P; Pérez-García, Fernando; Taniguchi, Hironori; Wendisch, Volker F

    2016-10-01

    L-arginine is a semi-essential amino acid with application in cosmetic, pharmaceutical, and food industries. Metabolic engineering strategies have been applied for overproduction of L-arginine by Corynebacterium glutamicum. LysE was the only known L-arginine exporter of this bacterium. However, an L-arginine-producing strain carrying a deletion of lysE still accumulated about 10 mM L-arginine in the growth medium. Overexpression of the putative putrescine and cadaverine export permease gene cgmA was shown to compensate for the lack of lysE with regard to L-arginine export. Moreover, plasmid-borne overexpression of cgmA rescued the toxic effect caused by feeding of the dipeptide Arg-Ala to lysE-deficient C. glutamicum and argO-deficient Escherichia coli strains. Deletion of the repressor gene cgmR improved L-arginine titers by 5 %. Production of L-lysine and L-citrulline was not affected by cgmA overexpression. Taken together, CgmA may function as an export system not only for the diamine putrescine and cadaverine but also for L-arginine. The major export system for L-lysine and L-arginine LysE may also play a role in L-citrulline export since production of L-citrulline was reduced when lysE was deleted and improved by 45 % when lysE was overproduced.

  17. CHD3 facilitates vRNP nuclear export by interacting with NES1 of influenza A virus NS2.

    PubMed

    Hu, Yong; Liu, Xiaokun; Zhang, Anding; Zhou, Hongbo; Liu, Ziduo; Chen, Huanchun; Jin, Meilin

    2015-03-01

    NS2 from influenza A virus mediates Crm1-dependent vRNP nuclear export through interaction with Crm1. However, even though the nuclear export signal 1 (NES1) of NS2 does not play a requisite role in NS2-Crm1 interaction, there is no doubt that NES1 is crucial for vRNP nuclear export. While the mechanism of the NES1 is still unclear, it is speculated that certain host partners might mediate the NES1 function through their interaction with NES1. In the present study, chromodomain-helicase-DNA-binding protein 3 (CHD3) was identified as a novel host nuclear protein for locating NS2 and Crm1 on dense chromatin for NS2 and Crm1-dependent vRNP nuclear export. CHD3 was confirmed to interact with NES1 in NS2, and a disruption to this interaction by mutation in NES1 significantly delayed viral vRNPs export and viral propagation. Further, the knockdown of CHD3 would affect the propagation of the wild-type virus but not the mutant with the weakened NS2-CHD3 interaction. Therefore, this study demonstrates that NES1 is required for maximal binding of NS2 to CHD3, and that the NS2-CHD3 interaction on the dense chromatin contributed to the NS2-mediated vRNP nuclear export.

  18. Markov Switching Autoregressive Conditional Heteroscedasticity (SWARCH) Model to Detect Financial Crisis in Indonesia Based on Import and Export Indicators

    NASA Astrophysics Data System (ADS)

    Sugiyanto; Zukhronah, Etik; Susanti, Yuliana; Rahma Dwi, Sisca

    2017-06-01

    A country is said to be a crisis when the financial system is experiencing a disruption that affects systems that can not function efficiently. The performance efficiency of macroeconomic indicators especially in imports and exports can be used to detect the financial crisis in Indonesia. Based on the import and export indicators from 1987 to 2015, the movement of these indicators can be modelled using SWARCH three states. The results showed that SWARCH (3,1) model was able to detect the crisis that occurred in Indonesia in 1997 and 2008. Using this model, it can be concluded that Indonesia is prone to financial crisis in 2016.

  19. Proposed Political Federation of East African Countries: ’Benefit’ to Tanzania

    DTIC Science & Technology

    2010-03-01

    minerals-gold, diamonds, tanzanite, coal, iron ores, nickels, natural gas, fertile agricultural and pasture land, forests and wildlife. In 2003...exports. The Musoma Dairy limited is a Tanzanian milk processor. The Musoma Dairy Limited complained that its exports had been denied entry into Kenya...by the Kenya Revenue Authority on the grounds that it failed the required qualifications of customs rules.60 The rules affecting the Musoma Dairy

  20. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization.

    PubMed

    Pinarbasi, Emile S; Cağatay, Tolga; Fung, Ho Yee Joyce; Li, Ying C; Chook, Yuh Min; Thomas, Philip J

    2018-05-04

    ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disease characterized by the redistribution of the RNA binding protein TDP-43 in affected neurons: from predominantly nuclear to aggregated in the cytosol. However, the determinants of TDP-43 localization and the cellular insults that promote redistribution are incompletely understood. Here, we show that the putative Nuclear Export Signal (NES) is not required for nuclear egress of TDP-43. Moreover, when the TDP-43 domain which contains the putative NES is fused to a reporter protein, YFP, the presence of the NES is not sufficient to mediate nuclear exclusion of the fusion protein. We find that the previously studied "∆NES" mutant, in which conserved hydrophobic residues are mutated to alanines, disrupts both solubility and splicing function. We further show that nuclear export of TDP-43 is independent of the exportin XPO1. Finally, we provide evidence that nuclear egress of TDP-43 is size dependent; nuclear export of dTomato TDP-43 is significantly impaired compared to Flag TDP-43. Together, these results suggest nuclear export of TDP-43 is predominantly driven by passive diffusion.

  1. SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

    PubMed Central

    Nogueira, Cristina; Erlmann, Patrik; Villeneuve, Julien; Santos, António JM; Martínez-Alonso, Emma; Martínez-Menárguez, José Ángel; Malhotra, Vivek

    2014-01-01

    TANGO1 binds and exports Procollagen VII from the endoplasmic reticulum (ER). In this study, we report a connection between the cytoplasmic domain of TANGO1 and SLY1, a protein that is required for membrane fusion. Knockdown of SLY1 by siRNA arrested Procollagen VII in the ER without affecting the recruitment of COPII components, general protein secretion, and retrograde transport of the KDEL-containing protein BIP, and ERGIC53. SLY1 is known to interact with the ER-specific SNARE proteins Syntaxin 17 and 18, however only Syntaxin 18 was required for Procollagen VII export. Neither SLY1 nor Syntaxin 18 was required for the export of the equally bulky Procollagen I from the ER. Altogether, these findings reveal the sorting of bulky collagen family members by TANGO1 at the ER and highlight the existence of different export pathways for secretory cargoes one of which is mediated by the specific SNARE complex containing SLY1 and Syntaxin 18. DOI: http://dx.doi.org/10.7554/eLife.02784.001 PMID:24842878

  2. CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.

    PubMed

    Le Floch, Renaud; Chiche, Johanna; Marchiq, Ibtissam; Naiken, Tanesha; Naïken, Tanesha; Ilc, Karine; Ilk, Karine; Murray, Clare M; Critchlow, Susan E; Roux, Danièle; Simon, Marie-Pierre; Pouysségur, Jacques

    2011-10-04

    Malignant tumors exhibit increased dependence on glycolysis, resulting in abundant export of lactic acid, a hypothesized key step in tumorigenesis. Lactic acid is mainly transported by two H(+)/lactate symporters, MCT1/MCT4, that require the ancillary protein CD147/Basigin for their functionality. First, we showed that blocking MCT1/2 in Ras-transformed fibroblasts with AR-C155858 suppressed lactate export, glycolysis, and tumor growth, whereas ectopic expression of MCT4 in these cells conferred resistance to MCT1/2 inhibition and reestablished tumorigenicty. A mutant-derivative, deficient in respiration (res(-)) and exclusively relying on glycolysis for energy, displayed low tumorigenicity. These res(-) cells could develop resistance to MCT1/2 inhibition and became highly tumorigenic by reactivating their endogenous mct4 gene, highlighting that MCT4, the hypoxia-inducible and tumor-associated lactate/H(+) symporter, drives tumorigenicity. Second, in the human colon adenocarcinoma cell line (LS174T), we showed that combined silencing of MCT1/MCT4 via inducible shRNA, or silencing of CD147/Basigin alone, significantly reduced glycolytic flux and tumor growth. However, both silencing approaches, which reduced tumor growth, displayed a low level of CD147/Basigin, a multifunctional protumoral protein. To gain insight into CD147/Basigin function, we designed experiments, via zinc finger nuclease-mediated mct4 and basigin knockouts, to uncouple MCTs from Basigin expression. Inhibition of MCT1 in MCT4-null, Basigin(high) cells suppressed tumor growth. Conversely, in Basigin-null cells, in which MCT activity had been maintained, tumorigenicity was not affected. Collectively, these findings highlight that the major protumoral action of CD147/Basigin is to control the energetics of glycolytic tumors via MCT1/MCT4 activity and that blocking lactic acid export provides an efficient anticancer strategy.

  3. CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

    PubMed Central

    Le Floch, Renaud; Chiche, Johanna; Marchiq, Ibtissam; Naiken, Tanesha; Ilc, Karine; Murray, Clare M.; Critchlow, Susan E.; Roux, Danièle; Simon, Marie-Pierre; Pouysségur, Jacques

    2011-01-01

    Malignant tumors exhibit increased dependence on glycolysis, resulting in abundant export of lactic acid, a hypothesized key step in tumorigenesis. Lactic acid is mainly transported by two H+/lactate symporters, MCT1/MCT4, that require the ancillary protein CD147/Basigin for their functionality. First, we showed that blocking MCT1/2 in Ras-transformed fibroblasts with AR-C155858 suppressed lactate export, glycolysis, and tumor growth, whereas ectopic expression of MCT4 in these cells conferred resistance to MCT1/2 inhibition and reestablished tumorigenicty. A mutant-derivative, deficient in respiration (res−) and exclusively relying on glycolysis for energy, displayed low tumorigenicity. These res− cells could develop resistance to MCT1/2 inhibition and became highly tumorigenic by reactivating their endogenous mct4 gene, highlighting that MCT4, the hypoxia-inducible and tumor-associated lactate/H+ symporter, drives tumorigenicity. Second, in the human colon adenocarcinoma cell line (LS174T), we showed that combined silencing of MCT1/MCT4 via inducible shRNA, or silencing of CD147/Basigin alone, significantly reduced glycolytic flux and tumor growth. However, both silencing approaches, which reduced tumor growth, displayed a low level of CD147/Basigin, a multifunctional protumoral protein. To gain insight into CD147/Basigin function, we designed experiments, via zinc finger nuclease-mediated mct4 and basigin knockouts, to uncouple MCTs from Basigin expression. Inhibition of MCT1 in MCT4-null, Basiginhigh cells suppressed tumor growth. Conversely, in Basigin-null cells, in which MCT activity had been maintained, tumorigenicity was not affected. Collectively, these findings highlight that the major protumoral action of CD147/Basigin is to control the energetics of glycolytic tumors via MCT1/MCT4 activity and that blocking lactic acid export provides an efficient anticancer strategy. PMID:21930917

  4. Application of TREECS Modeling System to Strontium-90 for Borschi Watershed near Chernobyl, Ukraine.

    PubMed

    Johnson, Billy E; Dortch, Mark S

    2014-05-01

    The Training Range Environmental Evaluation and Characterization System (TREECS™) (http://el.erdc.usace.army.mil/treecs/) is being developed by the U.S. Army Engineer Research and Development Center (ERDC) for the U.S. Army to forecast the fate of munitions constituents (MC) (such as high explosives (HE) and metals) found on firing/training ranges, as well as those subsequently transported to surface water and groundwater. The overall purpose of TREECS™ is to provide environmental specialists with tools to assess the potential for MC migration into surface water and groundwater systems and to assess range management strategies to ensure protection of human health and the environment. The multimedia fate/transport models within TREECS™ are mathematical models of reduced form (e.g., reduced dimensionality) that allow rapid application with less input data requirements compared with more complicated models. Although TREECS™ was developed for the fate of MC from military ranges, it has general applicability to many other situations requiring prediction of contaminant (including radionuclide) fate in multi-media environmental systems. TREECS™ was applied to the Borschi watershed near the Chernobyl Nuclear Power Plant, Ukraine. At this site, TREECS™ demonstrated its use as a modeling tool to predict the fate of strontium 90 ((90)Sr). The most sensitive and uncertain input for this application was the soil-water partitioning distribution coefficient (Kd) for (90)Sr. The TREECS™ soil model provided reasonable estimates of the surface water export flux of (90)Sr from the Borschi watershed when using a Kd for (90)Sr of 200 L/kg. The computed export for the year 2000 was 0.18% of the watershed inventory of (90)Sr compared to the estimated export flux of 0.14% based on field data collected during 1999-2001. The model indicated that assumptions regarding the form of the inventory, whether dissolved or in solid phase form, did not appreciably affect export rates. Also, the percentage of non-exchangeable adsorbed (90)Sr, which is uncertain and affects the amount of (90)Sr available for export, was fixed at 20% based on field data measurements. A Monte Carlo uncertainty analysis was conducted treating Kd as an uncertain input variable with a range of 100-300 L/kg. This analysis resulted in a range of 0.13-0.27% of inventory exported to surface water compared to 0.14% based on measured field data. Based on this model application, it was concluded that the export of (90)Sr from the Borschi watershed to surface water is predominantly a result of soil pore water containing dissolved (90)Sr being diverted to surface waters that eventually flow out of the watershed. The percentage of non-exchangeable adsorbed (90)Sr and the soil-water Kd are the two most sensitive and uncertain factors affecting the amount of export. The 200-year projections of the model showed an exponential decline in (90)Sr export fluxes from the watershed that should drop by a factor of 10 by the year 2100. This presentation will focus on TREECS capabilities and the case study done for the Borschi Watershed. Published by Elsevier Ltd.

  5. Reporter Dyes Demonstrate Functional Expression of Multidrug Resistance Proteins in the Marine Flatworm Macrostomum lignano: The Sponge-Derived Dye Ageladine A Is Not a Substrate of These Transporters

    PubMed Central

    Tietje, Kristin; Rivera-Ingraham, Georgina; Petters, Charlotte; Abele, Doris; Dringen, Ralf; Bickmeyer, Ulf

    2013-01-01

    The marine plathyhelminth Macrostomum lignano was recently isolated from Adriatic shore sediments where it experiences a wide variety of environmental challenges, ranging from hypoxia and reoxygenation, feeding on toxic algae, to exposure to anthropogenic contaminants. As multidrug resistance transporters constitute the first line of defense against toxins and toxicants we have studied the presence of such transporters in M. lignano in living animals by applying optical methods and pharmacological inhibitors that had been developed for mammalian cells. Application of the MDR1 inhibitor Verapamil or of the MRP1 inhibitors MK571 or Probenecid increased the intracellular fluorescence of the reporter dyes Fura-2 am, Calcein am, Fluo-3 am in the worms, but did not affect their staining with the dyes Rhodamine B, CMFDA or Ageladine A. The marine sponge alkaloid Ageladine A remained intracellularly trapped for several days in the worms, suggesting that it does not serve as substrate of multidrug resistance exporters. In addition, Ageladine A did not affect multidrug resistance-associated protein (MRP)-mediated dye export from M. lignano or the MRP1-mediated glutathione (GSH) export from cultured rat brain astrocytes. The data obtained demonstrate that life-imaging is a useful tool to address physiological drug export from intact marine transparent flatworms by using multiphoton scanning microscopy. PMID:24135911

  6. 77 FR 25944 - Amendment to the International Traffic in Arms Regulations: Revision of U.S. Munitions List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... broadly controls, ``Any other explosive not elsewhere identified in this category specifically designed... State. ACTION: Proposed rule. SUMMARY: As part of the President's Export Control Reform effort, the... the U.S. Munitions List (USML) to describe more precisely the articles warranting control on the USML...

  7. Expressing the sense of Congress that all direct and indirect subsidies that benefit the production or export of sugar by all major sugar producing and consuming countries should be eliminated.

    THOMAS, 113th Congress

    Rep. Yoho, Ted S. [R-FL-3

    2013-06-14

    House - 06/25/2013 Referred to the Subcommittee on General Farm Commodities and Risk Management. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  8. 75 FR 74673 - Pesticides; Regulation To Clarify Labeling of Pesticides for Export; Notification to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... Agriculture AGENCY: Environmental Protection Agency (EPA). ACTION: Notification to the Secretary of Agriculture. SUMMARY: This document notifies the public that the Administrator of EPA has forwarded to the Secretary of Agriculture a draft proposed rule as required by section 25(a) of the Federal Insecticide...

  9. 77 FR 16670 - Amendment to the International Traffic in Arms Regulations: Sri Lanka

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... International Traffic in Arms Regulations: Sri Lanka AGENCY: Department of State. ACTION: Final rule. SUMMARY... exception to the license denial policy toward Sri Lanka. This change allows for exports to Sri Lanka for... . ATTN: Regulatory Change, Part 126, Sri Lanka. SUPPLEMENTARY INFORMATION: Section 126.1(n) is amended to...

  10. 18 CFR 380.5 - Actions that require an environmental assessment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... REGULATORY COMMISSION, DEPARTMENT OF ENERGY REVISED GENERAL RULES REGULATIONS IMPLEMENTING THE NATIONAL... in §§ 380.4, 380.6 and 2.55 of this chapter, authorization for the site of new gas import/export... storage fields under section 7 of the Natural Gas Act. (5) New natural gas curtailment plans, or any...

  11. 77 FR 10732 - Cameron LNG, LLC; Application for Long-Term Authorization To Export Domestically Produced...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... Years AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil..., Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or Private Delivery... Activities, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence Avenue SW...

  12. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... [Reserved] D7 Contracts, policies, and marketing and allocation plans for electric power D8 Import or export... operational change D10 Treatment, storage, and disposal facilities for high-level waste and spent nuclear fuel... Contracts, Policies, and Marketing and Allocation Plans for Electric Power Establishment and implementation...

  13. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...] D7Contracts, policies, and marketing and allocation plans for electric power D8Import or export of natural gas... and Allocation Plans for Electric Power Establishment and implementation of contracts, policies, and marketing and allocation plans related to electric power acquisition that involve (1) The interconnection of...

  14. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...] D7Contracts, policies, and marketing and allocation plans for electric power D8Import or export of natural gas... and Allocation Plans for Electric Power Establishment and implementation of contracts, policies, and marketing and allocation plans related to electric power acquisition that involve (1) The interconnection of...

  15. 10 CFR Appendix C to Subpart D of... - Classes of Actions that Normally Require EAs But Not Necessarily EISs

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .../construction/operation of energy system prototypes C13. Import/export natural gas, minor new construction... Marketing Administration system-wide vegetation management program. C6Implementation of a Power Marketing Administration system-wide erosion control program. C7Establishment and implementation of contracts, policies...

  16. 76 FR 33192 - Notice of Request for Extension of Approval of an Information Collection; Phytosanitary Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... 2011. Kevin Shea, Acting Administrator, Animal and Plant Health Inspection Service. [FR Doc. 2011-14175... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2011-0025... Certification AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of approval of an...

  17. 75 FR 45607 - Application To Export Electric Energy; Manitoba Hydro

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... that the proposed action will not adversely impact on the reliability of the U.S. electric power supply... United States to Canada pursuant to section 202(e) of the Federal Power Act (FPA). DATES: Comments... electric energy from the United States to Canada as a power marketer using existing international...

  18. 76 FR 3881 - Application To Export Electric Energy; TransAlta Energy Marketing (U.S.) Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Energy Marketing (U.S.) Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: TransAlta Energy Marketing (U.S.) Inc. (TEMUS) has applied to renew its..., Federal power marketing agencies, and other entities within the United States. The existing international...

  19. 75 FR 29364 - Certain Coated Paper Suitable for High-Quality Print Graphics Using Sheet-Fed Presses From China...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... Indonesia AGENCY: United States International Trade Commission. ACTION: Scheduling of the final phase of...-fair-value imports from China and Indonesia of certain coated paper, provided for in subheadings 4810...) are being provided to manufacturers, producers, or exporters in China and Indonesia of certain coated...

  20. 77 FR 62532 - Agency Information Collection Activities; Proposed Collection; Comments Requested: Import/Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ... II Chemicals; DEA Forms 486 and 486A ACTION: 30-Day Notice. The Department of Justice (DOJ), Drug Enforcement Administration (DEA) will be submitting the following information collection request to the Office... number: DEA Forms 486 and 486A. Component: Office of Diversion Control, Drug Enforcement Administration...

  1. 75 FR 19665 - Notice of Action Subject to Intergovernmental Review Under Executive Order 12372

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... the address section. A copy of this notice also is being furnished to the respective State single... area-wide small business assistance plan adopted by a State authorized agency. DATES: A State single..., women, exporters, the disabled, and minorities. SBDC Program Requirements An SBDC must meet programmatic...

  2. 75 FR 2435 - Addition to the List of Validated End-Users in the People's Republic of China (PRC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security 15 CFR Part 748 [Docket No. 0908111226... (PRC) AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: In this final rule, the Bureau of Industry and Security (BIS) amends the Export Administration Regulations (EAR) to...

  3. 77 FR 34933 - Notice of Request for Extension of and Revision to an Approval of an Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... wooden handicrafts from China under certain conditions. This action allows for trade in Chinese wooden... have required Chinese exporters to complete a phytosanitary certificate. Therefore, the only burden associated with the import of Chinese wooden handicrafts is the identification tagging of packages. We are...

  4. 78 FR 55696 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... EXPORT-IMPORT BANK Sunshine Act Meeting ACTION: Notice of a Partially Open Meeting of the Board of...:00 p.m. The meeting will be held at Ex-Im Bank in Room 321, 811 Vermont Avenue NW., Washington, DC...: The meeting will be open to public observation for Item No. 1 only. FURTHER INFORMATION: Members of...

  5. Runoff changes have a land cover specific effect on the seasonal fluxes of terminal electron acceptors in the boreal catchments.

    PubMed

    Mattsson, Tuija; Lehtoranta, Jouni; Ekholm, Petri; Palviainen, Marjo; Kortelainen, Pirkko

    2017-12-01

    Climate change influences the volume and seasonal distribution of runoff in the northern regions. Here, we study how the seasonal variation in the runoff affects the concentrations and export of terminal electron acceptors (i.e. TEAs: NO 3 , Mn, Fe and SO 4 ) in different boreal land-cover classes. Also, we make a prediction how the anticipated climate change induced increase in runoff will alter the export of TEAs in boreal catchments. Our results show that there is a strong positive relationship between runoff and the concentration of NO 3 -N, Mn and Fe in agricultural catchments. In peaty catchments, the relationship is poorer and the concentrations of TEAs tend to decrease with increasing runoff. In forested catchments, the correlation between runoff and TEA concentrations was weak. In most catchments, the concentrations of SO 4 decrease with an increase in runoff regardless of the land cover or season. The wet years export much higher amounts of TEAs than the dry years. In southern agricultural catchments, the wet years increased the TEA export for both spring (January-May) and autumn (September-December) periods, while in the peaty and forested catchments in eastern and northern Finland the export only increased in the autumn. Our predictions for the year 2099 indicate that the export of TEAs will increase especially from agricultural but also from forested catchments. Additionally, the predictions show an increase in the export of Fe and SO 4 for all the catchments for the autumn. Thus, the climate induced change in the runoff regime is likely to alter the exported amount of TEAs and the timing of the export downstream. The changes in the amounts and timing in the export of TEAs have a potential to modify the mineralization pathways in the receiving water bodies, with feedbacks in the cycling of C, nutrients and metals in aquatic ecosystems. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX

    PubMed Central

    Hagan, A. K.; Berger, D.

    2017-01-01

    ABSTRACT Bacillus anthracis—a Gram-positive, spore-forming bacterium—causes anthrax, a highly lethal disease with high bacteremia titers. Such rapid growth requires ample access to nutrients, including iron. However, access to this critical metal is heavily restricted in mammals, which requires B. anthracis to employ petrobactin, an iron-scavenging small molecule known as a siderophore. Petrobactin biosynthesis is mediated by asb gene products, and import of the iron-bound (holo)-siderophore into the bacterium has been well studied. In contrast, little is known about the mechanism of petrobactin export following its production in B. anthracis cells. Using a combination of bioinformatics data, gene deletions, and laser ablation electrospray ionization mass spectrometry (LAESI-MS), we identified a resistance-nodulation-cell division (RND)-type transporter, termed ApeX, as a putative petrobactin exporter. Deletion of apeX abrogated export of intact petrobactin, which accumulated inside the cell. However, growth of ΔapeX mutants in iron-depleted medium was not affected, and virulence in mice was not attenuated. Instead, petrobactin components were determined to be exported through a different protein, which enables iron transport sufficient for growth, albeit with a slightly lower affinity for iron. This is the first report to identify a functional siderophore exporter in B. anthracis and the in vivo functionality of siderophore components. Moreover, this is the first application of LAESI-MS to sample a virulence factor/metabolite directly from bacterial culture media and cell pellets of a human pathogen. PMID:28900020

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Almasbahi, M.S.

    In a world of generalized floating exchange rates, it is not enough to solve the problem of exchange rate policy by determining whether to peg or float the currency under consideration. It is also necessary to choose to what major currency to peg. The main purpose of this study is to investigate and determine empirically the optimum currency peg for the Saudi riyal. To accomplish this goal, a simple conventional trade model, that includes variables found in many other studies of import and export demand, was used. In addition, an exchange rate term was added as a separate independent variablemore » in the import and export demand equations in order to assess the effect of exchange rate on the trade flows. The criteria for the optimal currency peg in this study were based on two factors. First, the error statistics for projected imports and exports using alternative exchange rate regimes. Second, variances of projected imports, exports and trade balance using alternative exchange rate regimes. The exchange rate has a significant impact on the Saudia Arabian trade flows which implies that changes in the riyals value affect the Saudi trade deficit. Moreover, the exchange rate has a more powerful effect on its aggregate imports than on the world demand for its exports. There is also a strong support for the hypothesis that the exchange rate affects the value of the Saudi bilateral trade with its five major trade partners. On the aggregate level, the SDR peg seems to be the best currency peg for the Saudi riyal since it provides the best prediction errors and the lowest variance for the trade balance. Finally, on the disaggregate level, the US dollar provides the best performance and yields the best results among all the six currency pegs considered in this study.« less

  8. Biophysical characterization of the outer membrane polysaccharide export protein and the polysaccharide co-polymerase protein from Xanthomonas campestris.

    PubMed

    Bianco, M I; Jacobs, M; Salinas, S R; Salvay, A G; Ielmini, M V; Ielpi, L

    2014-09-01

    This study investigated the structural and biophysical characteristics of GumB and GumC, two Xanthomonas campestris membrane proteins that are involved in xanthan biosynthesis. Xanthan is an exopolysaccharide that is thought to be a virulence factor that contributes to bacterial in planta growth. It also is one of the most important industrial biopolymers. The first steps of xanthan biosynthesis are well understood, but the polymerization and export mechanisms remain unclear. For this reason, the key proteins must be characterized to better understand these processes. Here we characterized, by biochemical and biophysical techniques, GumB, the outer membrane polysaccharide export protein, and GumC, the polysaccharide co-polymerase protein of the xanthan biosynthesis system. Our results suggested that recombinant GumB is a tetrameric protein in solution. On the other hand, we observed that both native and recombinant GumC present oligomeric conformation consistent with dimers and higher-order oligomers. The transmembrane segments of GumC are required for GumC expression and/or stability. These initial results provide a starting point for additional studies that will clarify the roles of GumB and GumC in the xanthan polymerization and export processes and further elucidate their functions and mechanisms of action. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Interdependence between transcription and mRNP processing and export, and its impact on genetic stability.

    PubMed

    Luna, Rosa; Jimeno, Sonia; Marín, Mercedes; Huertas, Pablo; García-Rubio, María; Aguilera, Andrés

    2005-06-10

    The conserved eukaryotic THO-TREX complex acts at the interface between transcription and mRNA export and affects transcription-associated recombination. To investigate the interdependence of nuclear mRNA processes and their impact on genomic integrity, we analyzed transcript accumulation and recombination of 40 selected mutants covering representative steps of the biogenesis and export of the messenger ribonucleoprotein particle (mRNP). None of the mutants analyzed shared the strong transcript-accumulation defect and hyperrecombination of THO mutants. Nevertheless, mutants in 3' end cleavage/polyadenylation, nuclear exosome, and mRNA export showed a weak but significant effect on recombination and transcript accumulation. Mutants of the nuclear exosome (rrp6) and 3' end processing factors (rna14 and rna15) showed inefficient transcription elongation and genetic interactions with THO. The results suggest a tight interdependence among mRNP biogenesis steps and transcription and an unexpected effect of the nuclear exosome and the cleavage/polyadenylation factors on transcription elongation and genetic integrity.

  10. Thiol-facilitated cell export and desorption of methylmercury by anaerobic bacteria

    DOE PAGES

    Lin, Hui; Lu, Xia; Liang, Liyuan; ...

    2015-09-04

    Neurotoxic methylmercury (MeHg), formed by anaerobic bacteria, is shown to be rapidly excreted from the cell, but the mechanism of this process is unclear. Using both Geobacter sulfurreducens PCA and Desulfovibrio desulfuricans ND132 strains, we investigated the factors affecting export and distribution of MeHg in mercury methylation and MeHg sorption-desorption assays. Thiols, such as cysteine, were found to greatly facilitate desorption and export of MeHg, particularly by PCA cells. However, in cysteine-free assays (4 h) >90% of the synthesized MeHg was associated with PCA, among which ~73% was sorbed on the cell surface and 19% remained inside the cells. Inmore » comparison, a majority of the MeHg (70%) was exported by ND132, leaving ~20% of the MeHg sorbed on the surface and 10% inside the cells. When MeHg was added directly to the cell suspensions, ND132 adsorbed much lower MeHg but took up more MeHg inside cells than PCA did. These results demonstrate that MeHg export is bacteria strain-specific, time dependent, and is influenced by thiols, implicating important roles of ligand complexation in facilitating MeHg production and mobilization in the environment.« less

  11. Forecasting on the total volumes of Malaysia's imports and exports by multiple linear regression

    NASA Astrophysics Data System (ADS)

    Beh, W. L.; Yong, M. K. Au

    2017-04-01

    This study is to give an insight on the doubt of the important of macroeconomic variables that affecting the total volumes of Malaysia's imports and exports by using multiple linear regression (MLR) analysis. The time frame for this study will be determined by using quarterly data of the total volumes of Malaysia's imports and exports covering the period between 2000-2015. The macroeconomic variables will be limited to eleven variables which are the exchange rate of US Dollar with Malaysia Ringgit (USD-MYR), exchange rate of China Yuan with Malaysia Ringgit (RMB-MYR), exchange rate of European Euro with Malaysia Ringgit (EUR-MYR), exchange rate of Singapore Dollar with Malaysia Ringgit (SGD-MYR), crude oil prices, gold prices, producer price index (PPI), interest rate, consumer price index (CPI), industrial production index (IPI) and gross domestic product (GDP). This study has applied the Johansen Co-integration test to investigate the relationship among the total volumes to Malaysia's imports and exports. The result shows that crude oil prices, RMB-MYR, EUR-MYR and IPI play important roles in the total volumes of Malaysia's imports. Meanwhile crude oil price, USD-MYR and GDP play important roles in the total volumes of Malaysia's exports.

  12. Relation between inherent optical properties and land use and land cover across Gulf Coast estuaries

    EPA Science Inventory

    Land use and land cover (LULC) can affect the watershed exports of optically active constituents such as suspended particulate matter and colored dissolved organic matter, and in turn affect estuarine optical properties. We collected optical data from six estuaries in the northea...

  13. Involvement of Vacuolar Sequestration and Active Transport in Tolerance of Saccharomyces cerevisiae to Hop Iso-α-Acids▿ † ¶

    PubMed Central

    Hazelwood, Lucie A.; Walsh, Michael C.; Pronk, Jack T.; Daran, Jean-Marc

    2010-01-01

    The hop plant, Humulus lupulus L., has an exceptionally high content of secondary metabolites, the hop α-acids, which possess a range of beneficial properties, including antiseptic action. Studies performed on the mode of action of hop iso-α-acids have hitherto been restricted to lactic acid bacteria. The present study investigated molecular mechanisms of hop iso-α-acid resistance in the model eukaryote Saccharomyces cerevisiae. Growth inhibition occurred at concentrations of hop iso-α-acids that were an order of magnitude higher than those found with hop-tolerant prokaryotes. Chemostat-based transcriptome analysis and phenotype screening of the S. cerevisiae haploid gene deletion collection were used as complementary methods to screen for genes involved in hop iso-α-acid detoxification and tolerance. This screening and further analysis of deletion mutants confirmed that yeast tolerance to hop iso-α-acids involves three major processes, active proton pumping into the vacuole by the vacuolar-type ATPase to enable vacuolar sequestration of iso-α-acids and alteration of cell wall structure and, to a lesser extent, active export of iso-α-acids across the plasma membrane. Furthermore, iso-α-acids were shown to affect cellular metal homeostasis by acting as strong zinc and iron chelators. PMID:19915041

  14. 78 FR 58267 - Notice of Request for Extension of Approval of an Information Collection; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... Hatching Eggs for Export AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Extension of... hatching eggs from the United States. DATES: We will consider all comments that we receive on or before... and hatching eggs from the United States, contact Dr. Antonio Ramirez, Senior Staff Veterinarian, NCIE...

  15. 78 FR 19696 - Orders Granting Authority To Import and Export Natural Gas, To Import Liquefied Natural Gas, To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ...: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives notice that during December 2012, it issued orders... site at http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders-2012.html . They are...

  16. 77 FR 4028 - Orders Granting, Amending and Vacating Authority To Import and Export Natural Gas and Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-26

    ..., L.P 92-35-LNG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives notice that during December... site at http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders-2011.html . They are...

  17. 77 FR 50680 - Notice of Orders Granting Applications and an Order Vacating Authority To Import and Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... June 2012 AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. FE... & GAS COMPANY, 12-69-NG LLC. MONETA ENERGY SERVICES, LTD 12-70-NG SUMMARY: The Office of Fossil Energy....fossil.energy.gov/programs/gasregulation/authorizations/Orders-2012.html . They are also available for...

  18. 77 FR 19277 - Orders Granting Authority To Import and Export Natural Gas and Liquefied Natural Gas During...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... of Fossil Energy, Department of Energy. ACTION: Notice of orders. SUMMARY: The Office of Fossil... attached appendix and may be found on the FE Web site at http://www.fossil.energy.gov/programs... of Fossil Energy, Office of Natural Gas Regulatory Activities, Docket Room 3E-033, Forrestal Building...

  19. 78 FR 35263 - Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Previously...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ...: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of... of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or Private Delivery... and Supply, Office of Fossil Energy, Forrestal Building, Room 3E-042, 1000 Independence Avenue SW...

  20. 78 FR 46581 - Orders Granting Authority To Import and Export Natural Gas, and To Import Liquefied Natural Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... CANADA, INC 13-74-NG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy gives notice that during... http://www.fossil.energy.gov/programs/gasregulation/authorizations/Orders-2012.html . They are also...

  1. 15 CFR Supplement No. 1 to Part 766 - Guidance on Charging and Penalty Determinations in Settlement of Administrative Enforcement Cases

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Responding to Violations The Office of Export Enforcement (OEE), among other responsibilities, investigates... authorization issued thereunder. When it appears that such a violation has occurred, OEE investigations may lead... Department of Justice for criminal prosecution. The type of enforcement action initiated by OEE will depend...

  2. 15 CFR Supplement No. 1 to Part 766 - Guidance on Charging and Penalty Determinations in Settlement of Administrative Enforcement Cases

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Responding to Violations The Office of Export Enforcement (OEE), among other responsibilities, investigates... authorization issued thereunder. When it appears that such a violation has occurred, OEE investigations may lead... Department of Justice for criminal prosecution. The type of enforcement action initiated by OEE will depend...

  3. 15 CFR Supplement No. 1 to Part 766 - Guidance on Charging and Penalty Determinations in Settlement of Administrative Enforcement Cases

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Responding to Violations The Office of Export Enforcement (OEE), among other responsibilities, investigates... authorization issued thereunder. When it appears that such a violation has occurred, OEE investigations may lead... Department of Justice for criminal prosecution. The type of enforcement action initiated by OEE will depend...

  4. 78 FR 54199 - Effectiveness of Licensing Procedures for Exportation of Agricultural Commodities, Medicine, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... Sudan and Iran; Comment Request AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Request for... agricultural commodities, medicine, and medical devices to Sudan and Iran. Pursuant to section 906(c) of the... agricultural commodities, medicine, and medical devices to Sudan and Iran are set forth in 31 CFR 538.523-526...

  5. 77 FR 72837 - Golden Pass Products LLC; Application for Long-Term Authorization To Export Liquefied Natural Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ...-Free Trade Agreement Countries for a 25-Year Period AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives...), Office of Natural Gas Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC...

  6. 77 FR 35317 - Amendment to the International Traffic in Arms Regulations: Revision of U.S. Munitions List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... State. ACTION: Proposed rule. SUMMARY: As part of the President's Export Control Reform effort, the... materials warranting control on the USML. The revisions to this rule are part of the Department of State's... Directorate of Defense Trade Controls Web site at www.pmddtc.state.gov . Parties who wish to comment...

  7. 77 FR 74472 - Application to Export Electric Energy; Energia Renovable S.C., LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... Renovable S.C., LLC AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Energia Renovable S.C., LLC (Energia Renovable) has applied for authority to transmit....C. 7151(b), 7172(f)) and require authorization under section 202(e) of the FPA (16 U.S.C.824a(e...

  8. Early detection of fungi damage in citrus using NIR spectroscopy

    NASA Astrophysics Data System (ADS)

    Blasco, Jose; Ortiz, Coral; Sabater, Maria D.; Molto, Enrique

    2000-12-01

    Early detection of defects and diseases in fruit helps to correctly classify them and make more adequate decisions about the destination of the product: internal market, export or industry. An early fungi infection detection is especially important because a few infected fruits can disseminate the infection to a whole batch, causing great economic losses and affecting to further exports. Ensure products with excellent quality and absolute absence of fungi infections is particularly important in those batches for long conservation or to be exported. The main objective of this work is to detect the fungi infections before they can be visible. Near Infrared spectroscopy has been employed in this work, because it is a non-destructive technique and can be easily implemented on line due to the high speed and simplicity of the process.

  9. Severe neurocognitive and growth disorders due to variation in THOC2, an essential component of nuclear mRNA export machinery.

    PubMed

    Kumar, Raman; Gardner, Alison; Homan, Claire C; Douglas, Evelyn; Mefford, Heather; Wieczorek, Dagmar; Lüdecke, Hermann-Josef; Stark, Zornitza; Sadedin, Simon; Nowak, Catherine Bearce; Douglas, Jessica; Parsons, Gretchen; Mark, Paul; Loidi, Lourdes; Herman, Gail E; Mihalic Mosher, Theresa; Gillespie, Meredith K; Brady, Lauren; Tarnopolsky, Mark; Madrigal, Irene; Eiris, Jesús; Domènech Salgado, Laura; Rabionet, Raquel; Strom, Tim M; Ishihara, Naoko; Inagaki, Hidehito; Kurahashi, Hiroki; Dudding-Byth, Tracy; Palmer, Elizabeth E; Field, Michael; Gecz, Jozef

    2018-05-31

    Highly conserved TREX-mediated mRNA export is emerging as a key pathway in neuronal development and differentiation. TREX subunit variants cause neurodevelopmental disorders (NDDs) by interfering with mRNA export from the cell nucleus to the cytoplasm. Previously we implicated four missense variants in the X-linked THOC2 gene in intellectual disability (ID). We now report an additional six affected individuals from five unrelated families with two de novo and three maternally-inherited pathogenic or likely pathogenic variants in THOC2 extending the genotypic and phenotypic spectrum. These comprise three rare missense THOC2 variants that affect evolutionarily conserved amino acid residues and reduce protein stability and two with canonical splice-site THOC2 variants that result in C-terminally truncated THOC2 proteins. We present detailed clinical assessment and functional studies on a de novo variant in a female with an epileptic encephalopathy and discuss an additional four families with rare variants in THOC2 with supportive evidence for pathogenicity. Severe neurocognitive features, including movement and seizure disorders were observed in this cohort. Taken together our data show that even subtle alterations to the canonical molecular pathways such as mRNA export, otherwise essential for cellular life, can be compatible with life, but lead to NDDs in humans. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  10. A lake classification concept for a more accurate global estimate of the dissolved inorganic carbon export from terrestrial ecosystems to inland waters.

    PubMed

    Engel, Fabian; Farrell, Kaitlin J; McCullough, Ian M; Scordo, Facundo; Denfeld, Blaize A; Dugan, Hilary A; de Eyto, Elvira; Hanson, Paul C; McClure, Ryan P; Nõges, Peeter; Nõges, Tiina; Ryder, Elizabeth; Weathers, Kathleen C; Weyhenmeyer, Gesa A

    2018-03-26

    The magnitude of lateral dissolved inorganic carbon (DIC) export from terrestrial ecosystems to inland waters strongly influences the estimate of the global terrestrial carbon dioxide (CO 2 ) sink. At present, no reliable number of this export is available, and the few studies estimating the lateral DIC export assume that all lakes on Earth function similarly. However, lakes can function along a continuum from passive carbon transporters (passive open channels) to highly active carbon transformers with efficient in-lake CO 2 production and loss. We developed and applied a conceptual model to demonstrate how the assumed function of lakes in carbon cycling can affect calculations of the global lateral DIC export from terrestrial ecosystems to inland waters. Using global data on in-lake CO 2 production by mineralization as well as CO 2 loss by emission, primary production, and carbonate precipitation in lakes, we estimated that the global lateral DIC export can lie within the range of [Formula: see text] to [Formula: see text] Pg C yr -1 depending on the assumed function of lakes. Thus, the considered lake function has a large effect on the calculated lateral DIC export from terrestrial ecosystems to inland waters. We conclude that more robust estimates of CO 2 sinks and sources will require the classification of lakes into their predominant function. This functional lake classification concept becomes particularly important for the estimation of future CO 2 sinks and sources, since in-lake carbon transformation is predicted to be altered with climate change.

  11. A lake classification concept for a more accurate global estimate of the dissolved inorganic carbon export from terrestrial ecosystems to inland waters

    NASA Astrophysics Data System (ADS)

    Engel, Fabian; Farrell, Kaitlin J.; McCullough, Ian M.; Scordo, Facundo; Denfeld, Blaize A.; Dugan, Hilary A.; de Eyto, Elvira; Hanson, Paul C.; McClure, Ryan P.; Nõges, Peeter; Nõges, Tiina; Ryder, Elizabeth; Weathers, Kathleen C.; Weyhenmeyer, Gesa A.

    2018-04-01

    The magnitude of lateral dissolved inorganic carbon (DIC) export from terrestrial ecosystems to inland waters strongly influences the estimate of the global terrestrial carbon dioxide (CO2) sink. At present, no reliable number of this export is available, and the few studies estimating the lateral DIC export assume that all lakes on Earth function similarly. However, lakes can function along a continuum from passive carbon transporters (passive open channels) to highly active carbon transformers with efficient in-lake CO2 production and loss. We developed and applied a conceptual model to demonstrate how the assumed function of lakes in carbon cycling can affect calculations of the global lateral DIC export from terrestrial ecosystems to inland waters. Using global data on in-lake CO2 production by mineralization as well as CO2 loss by emission, primary production, and carbonate precipitation in lakes, we estimated that the global lateral DIC export can lie within the range of {0.70}_{-0.31}^{+0.27} to {1.52}_{-0.90}^{+1.09} Pg C yr-1 depending on the assumed function of lakes. Thus, the considered lake function has a large effect on the calculated lateral DIC export from terrestrial ecosystems to inland waters. We conclude that more robust estimates of CO2 sinks and sources will require the classification of lakes into their predominant function. This functional lake classification concept becomes particularly important for the estimation of future CO2 sinks and sources, since in-lake carbon transformation is predicted to be altered with climate change.

  12. Inspection report: the Department of Energy's export licensing process for dual-use and munitions commodities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Friedman, Gregory H.

    1999-05-01

    Export of commodities, encouraged by both the private sector and the Federal Government, helps to improve our position in the global economy and is in the national interest of the US. However, exports of commodities or technologies, without regard to whether they may significantly contribute to the military potential of individual countries or combination of countries or enhance the proliferation of weapons of mass destruction, may adversely affect the national security of the US. The Federal Government, therefore, implements several laws, Executive Orders, and regulations to control the export of certain commodities and technologies. These commodities and technologies require amore » license for export. Some of the controlled items are designated as ''dual-use,'' that is, commodities and technologies that have both civilian and military application. Some dual-use commodities are designated as ''nuclear dual-use''--items controlled for nuclear nonproliferation purposes. Another group of controlled commodities is designated as munitions, which are goods and technologies that have solely military uses. The Department of Energy (Energy) conducts reviews of export license applications for nuclear dual-use items and certain munitions. On August 26, 1998, the Chairman of the Senate Committee on Governmental Affairs requested that the Inspectors General from the Departments of Commerce, Defense, Energy, State, and Treasury, and the Central Intelligence Agency (CIA), update and expand on a 1993 interagency review conducted by the Inspectors General of the Departments of Commerce, Defense, Energy, and State of the export licensing processes for dual-use and munitions commodities.« less

  13. Estimates of ikaite export from sea ice to the underlying seawater in a sea ice-seawater mesocosm

    NASA Astrophysics Data System (ADS)

    Geilfus, Nicolas-Xavier; Galley, Ryan J.; Else, Brent G. T.; Campbell, Karley; Papakyriakou, Tim; Crabeck, Odile; Lemes, Marcos; Delille, Bruno; Rysgaard, Søren

    2016-09-01

    The precipitation of ikaite and its fate within sea ice is still poorly understood. We quantify temporal inorganic carbon dynamics in sea ice from initial formation to its melt in a sea ice-seawater mesocosm pool from 11 to 29 January 2013. Based on measurements of total alkalinity (TA) and total dissolved inorganic carbon (TCO2), the main processes affecting inorganic carbon dynamics within sea ice were ikaite precipitation and CO2 exchange with the atmosphere. In the underlying seawater, the dissolution of ikaite was the main process affecting inorganic carbon dynamics. Sea ice acted as an active layer, releasing CO2 to the atmosphere during the growth phase, taking up CO2 as it melted and exporting both ikaite and TCO2 into the underlying seawater during the whole experiment. Ikaite precipitation of up to 167 µmol kg-1 within sea ice was estimated, while its export and dissolution into the underlying seawater was responsible for a TA increase of 64-66 µmol kg-1 in the water column. The export of TCO2 from sea ice to the water column increased the underlying seawater TCO2 by 43.5 µmol kg-1, suggesting that almost all of the TCO2 that left the sea ice was exported to the underlying seawater. The export of ikaite from the ice to the underlying seawater was associated with brine rejection during sea ice growth, increased vertical connectivity in sea ice due to the upward percolation of seawater and meltwater flushing during sea ice melt. Based on the change in TA in the water column around the onset of sea ice melt, more than half of the total ikaite precipitated in the ice during sea ice growth was still contained in the ice when the sea ice began to melt. Ikaite crystal dissolution in the water column kept the seawater pCO2 undersaturated with respect to the atmosphere in spite of increased salinity, TA and TCO2 associated with sea ice growth. Results indicate that ikaite export from sea ice and its dissolution in the underlying seawater can potentially hamper the effect of oceanic acidification on the aragonite saturation state (Ωaragonite) in fall and in winter in ice-covered areas, at the time when Ωaragonite is smallest.

  14. The melamine incident: implications for international food and feed safety.

    PubMed

    Gossner, Céline Marie-Elise; Schlundt, Jørgen; Ben Embarek, Peter; Hird, Susan; Lo-Fo-Wong, Danilo; Beltran, Jose Javier Ocampo; Teoh, Keng Ngee; Tritscher, Angelika

    2009-12-01

    A major food safety incident in China was made public in September 2008. Kidney and urinary tract effects, including kidney stones, affected about 300,000 Chinese infants and young children, with six reported deaths. Melamine had been deliberately added at milk-collecting stations to diluted raw milk ostensibly to boost its protein content. Subsequently, melamine has been detected in many milk and milk-containing products, as well as other food and feed products, which were also exported to many countries worldwide. The melamine event represents one of the largest deliberate food contamination incidents. We provide a description and analysis of this event to determine the global implications on food and feed safety. A series of factors, including the intentional character of the milk contamination, the young age of the population affected, the large number of potentially contaminated products, the global distribution of these products, and the delay in reporting led this event to take on unexpected proportions. This incident illustrated the complexity of international trade of food products and food ingredients that required immediate actions at international level. Managing food-safety events should be done internationally and early on as soon as multinational consequences are expected. Collaboration between food-safety authorities worldwide is needed to efficiently exchange information and to enable tracking and recalling of affected products to ensure food safety and to protect public health.

  15. The Melamine Incident: Implications for International Food and Feed Safety

    PubMed Central

    Gossner, Céline Marie-Elise; Schlundt, Jørgen; Ben Embarek, Peter; Hird, Susan; Lo-Fo-Wong, Danilo; Beltran, Jose Javier Ocampo; Teoh, Keng Ngee; Tritscher, Angelika

    2009-01-01

    Background A major food safety incident in China was made public in September 2008. Kidney and urinary tract effects, including kidney stones, affected about 300,000 Chinese infants and young children, with six reported deaths. Melamine had been deliberately added at milk-collecting stations to diluted raw milk ostensibly to boost its protein content. Subsequently, melamine has been detected in many milk and milk-containing products, as well as other food and feed products, which were also exported to many countries worldwide. Objectives The melamine event represents one of the largest deliberate food contamination incidents. We provide a description and analysis of this event to determine the global implications on food and feed safety. Discussions A series of factors, including the intentional character of the milk contamination, the young age of the population affected, the large number of potentially contaminated products, the global distribution of these products, and the delay in reporting led this event to take on unexpected proportions. This incident illustrated the complexity of international trade of food products and food ingredients that required immediate actions at international level. Conclusion Managing food-safety events should be done internationally and early on as soon as multinational consequences are expected. Collaboration between food-safety authorities worldwide is needed to efficiently exchange information and to enable tracking and recalling of affected products to ensure food safety and to protect public health. PMID:20049196

  16. "Agricultural Statecraft" in the Cold War: a case study of Poland and the West from 1945 to 1957.

    PubMed

    Spaulding, Robert Mark

    2009-01-01

    This paper examines how the rise and fall of Polish agriculture affected the larger political and economic relationship among Poland and three key members of the western alliance - the United States, the United Kingdom, and the Federal Republic of Germany - in the first decade of the Cold War. This period is revealing precisely because the reversal of fortunes in the Polish agricultural economy required the Polish government and some western counterparts to maneuver through periods of both agricultural advantage and disadvantage. Agricultural strategies as means and ends motivated the Polish, British, West German, and American governments to actions that bent, stretched, and limited some well-established practices in Cold War relations across divided Europe. By explicating the political consequences of changing flows of agricultural exports and imports in one specific context, this essay serves as case study of the role of agriculture in the global context of the Cold War.

  17. 77 FR 109 - Inquiry To Learn Whether Businesses Assert Business Confidentiality Claims Regarding Waste Import...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-03

    ... definition of ``affected business,'' and are not covered by today's notice. They consist of any business that.... Certain businesses, however, do not meet the definition of ``affected business,'' and are not covered by... Businesses Assert Business Confidentiality Claims Regarding Waste Import and Export AGENCY: Environmental...

  18. Space Food

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In planning for the long duration Apollo missions, NASA conducted extensive research into space food. One of the techniques developed was freeze drying. Action Products commercialized this technique, concentrating on snack food including the first freeze-dried ice cream. The foods are cooked, quickly frozen and then slowly heated in a vacuum chamber to remove the ice crystals formed by the freezing process. The final product retains 98 percent of its nutrition and weighs only 20 percent of its original weight. Action snacks are sold at museums, NASA facilities and are exported to a number of foreign countries. Sales run to several million dollars annually.

  19. Simulation of runoff and nutrient export from a typical small watershed in China using the Hydrological Simulation Program-Fortran.

    PubMed

    Li, Zhaofu; Liu, Hongyu; Luo, Chuan; Li, Yan; Li, Hengpeng; Pan, Jianjun; Jiang, Xiaosan; Zhou, Quansuo; Xiong, Zhengqin

    2015-05-01

    The Hydrological Simulation Program-Fortran (HSPF), which is a hydrological and water-quality computer model that was developed by the United States Environmental Protection Agency, was employed to simulate runoff and nutrient export from a typical small watershed in a hilly eastern monsoon region of China. First, a parameter sensitivity analysis was performed to assess how changes in the model parameters affect runoff and nutrient export. Next, the model was calibrated and validated using measured runoff and nutrient concentration data. The Nash-Sutcliffe efficiency (E NS ) values of the yearly runoff were 0.87 and 0.69 for the calibration and validation periods, respectively. For storms runoff events, the E NS values were 0.93 for the calibration period and 0.47 for the validation period. Antecedent precipitation and soil moisture conditions can affect the simulation accuracy of storm event flow. The E NS values for the total nitrogen (TN) export were 0.58 for the calibration period and 0.51 for the validation period. In addition, the correlation coefficients between the observed and simulated TN concentrations were 0.84 for the calibration period and 0.74 for the validation period. For phosphorus export, the E NS values were 0.89 for the calibration period and 0.88 for the validation period. In addition, the correlation coefficients between the observed and simulated orthophosphate concentrations were 0.96 and 0.94 for the calibration and validation periods, respectively. The nutrient simulation results are generally satisfactory even though the parameter-lumped HSPF model cannot represent the effects of the spatial pattern of land cover on nutrient export. The model parameters obtained in this study could serve as reference values for applying the model to similar regions. In addition, HSPF can properly describe the characteristics of water quantity and quality processes in this area. After adjustment, calibration, and validation of the parameters, the HSPF model is suitable for hydrological and water-quality simulations in watershed planning and management and for designing best management practices.

  20. Estrogen Treatment After Ovariectomy Protects Against Fatty Liver and May Improve Pathway-Selective Insulin Resistance

    PubMed Central

    Zhu, Lin; Brown, William C.; Cai, Qing; Krust, Andrée; Chambon, Pierre; McGuinness, Owen P.; Stafford, John M.

    2013-01-01

    Pathway-selective insulin resistance where insulin fails to suppress hepatic glucose production but promotes liver fat storage may underlie glucose and lipid abnormalities after menopause. We tested the mechanisms by which estrogen treatment may alter the impact of a high-fat diet (HFD) when given at the time of ovariectomy (OVX) in mice. Female C57BL/6J mice underwent sham operation, OVX, or OVX with estradiol (E2) treatment and were fed an HFD. Hyperinsulinemic-euglycemic clamps were used to assess insulin sensitivity, tracer incorporation into hepatic lipids, and liver triglyceride export. OVX mice had increased adiposity that was prevented with E2 at the time of OVX. E2 treatment increased insulin sensitivity with OVX and HFD. In sham and OVX mice, HFD feeding induced fatty liver, and insulin reduced hepatic apoB100 and liver triglyceride export. E2 treatment reduced liver lipid deposition and prevented the decrease in liver triglyceride export during hyperinsulinemia. In mice lacking the liver estrogen receptor α, E2 after OVX limited adiposity but failed to improve insulin sensitivity, to limit liver lipid deposition, and to prevent insulin suppression of liver triglyceride export. In conclusion, estrogen treatment may reverse aspects of pathway-selective insulin resistance by promoting insulin action on glucose metabolism but limiting hepatic lipid deposition. PMID:22966069

  1. Flexible Coordination in Resource-Constrained Domains

    DTIC Science & Technology

    1994-07-01

    Experiments (TIEs) with planning technologies developed at both BBN (FMERG) and SRI ( SOCAP ). We have also exported scheduling support capabilities provided by...SRI’s SOCAP course of action (COA) plan generator. "* Development and demonstration of distributed, multi-level deployment scheduling - Through analysis...scheduler was adapted for integration with the SOCAP planning system to provide feedback on transportation feasibility during generation of the

  2. 78 FR 35014 - Orders Granting Authority to Import and Export Natural Gas, and to Import Liquefied Natural Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy... in the attached appendix and may be found on the FE Web site at http://www.fossil.energy.gov/programs... of Fossil Energy, Office of Natural Gas Regulatory Activities, Docket Room 3E-033, Forrestal Building...

  3. 77 FR 12274 - Orders Granting Authority To Import and Export Natural Gas and Liquefied Natural Gas During...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. FE Docket Nos. DOMINION COVE POINT... Fossil Energy (FE) of the Department of Energy gives notice that during January 2012, it issued Orders... in the attached appendix and may be found on the FE Web site at http://www.fossil.energy.gov/programs...

  4. 77 FR 31838 - Notice of Orders Granting Authority to Import and Export Natural Gas and Liquefied Natural Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ...: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. FE Docket Nos. Prometheus... Resources, Inc 12-42-NG Minnesota Energy Resources Corporation... 12-40-NG SUMMARY: The Office of Fossil... attached appendix and may be found on the FE Web site at http://www.fossil.energy.gov/programs...

  5. 77 FR 33446 - Jordan Cove Energy Project, L.P.; Application for Long-Term Authorization to Export Liquefied...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Resources to Non-Free Trade Agreement Countries for a 25-Year Period AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE... Mail: U.S. Department of Energy (FE-34), Office of Natural Gas Regulatory Activities, Office of Fossil...

  6. 78 FR 34084 - Freeport-McMoRan Energy LLC; Application for Long-Term Authorization To Export Liquefied Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ...-Free Trade Agreement Countries for a 30- Year Period AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department of Energy (DOE) gives... Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC 20026-4375. Hand Delivery or Private...

  7. 76 FR 18347 - Removal of the List of Ports of Embarkation and Export Inspection Facilities From the Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0... references therein to suspension of approval, since the paragraph did not draw a clear distinction between... Flexibility Act, we have analyzed the potential economic effects of this action on small entities. The...

  8. Erythropoietin and carbamylated erythropoietin promote histone deacetylase 5 phosphorylation and nuclear export in rat hippocampal neurons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jo, Hye-Ryeong; Kim, Yong-Seok; Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, 17 Haengdang-dong, Sungdong-gu, Seoul 133-791

    2016-01-29

    Erythropoietin (EPO) produces neurotrophic effects in animal model of neurodegeneration. However, clinical use of EPO is limited due to thrombotic risk. Carbamylated EPO (cEPO), devoid of thrombotic risk, has been proposed as a novel neuroprotective and neurotrophic agent although the molecular mechanisms of cEPO remain incomplete. Here, we show a previously unidentified role of histone deacetylase 5 (HDAC5) in the actions of EPO and cEPO. EPO and cEPO regulate the HDAC5 phosphorylation at two critical sites, Ser259 and Ser498 through a protein kinase D (PKD) dependent pathway. In addition, EPO and cEPO rapidly stimulates nuclear export of HDAC5 in ratmore » hippocampal neurons which expressing HDAC5-GFP. Consequently, EPO and cEPO enhanced the myocyte enhancer factor-2 (MEF2) target gene expression. Taken together, our results reveal that EPO and cEPO mediate MEF2 target gene expression via the regulation of HDAC5 phosphorylation at Ser259/498, and suggest that HDAC5 could be a potential mechanism contributing to the therapeutic actions of EPO and cEPO.« less

  9. Modeling study of air pollution due to the manufacture of export goods in China's Pearl River Delta.

    PubMed

    Streets, David G; Yu, Carolyne; Bergin, Michael H; Wang, Xuemei; Carmichael, Gregory R

    2006-04-01

    The Pearl River Delta is a major manufacturing region on the south coast of China that produces more than dollar 100 billion of goods annually for export to North America, Europe, and other parts of Asia. Considerable air pollution is caused by the manufacturing industries themselves and by the power plants, trucks, and ships that support them. We estimate that 10-40% of emissions of primary SO2, NO(x), RSP, and VOC in the region are caused by export-related activities. Using the STEM-2K1 atmospheric transport model, we estimate that these emissions contribute 5-30% of the ambient concentrations of SO2, NO(x), NO(z), and VOC in the region. One reason that the exported goods are cheap and therefore attractive to consumers in developed countries is that emission controls are lacking or of low performance. We estimate that state-of-the-art controls could be installed at an annualized cost of dollar 0.3-3 billion, representing 0.3-3% of the value of the goods produced. We conclude that mitigation measures could be adopted without seriously affecting the prices of exported goods and would achieve considerable human health and other benefits in the form of reduced air pollutant concentrations in densely populated urban areas.

  10. Dissolved organic carbon export and its contribution to the carbon budget in a boreal peat landscape undergoing rapid permafrost thaw

    NASA Astrophysics Data System (ADS)

    Sonnentag, O.; Fouche, J.; Helbig, M.; Karoline, W.; Hould Gosselin, G.; Hanisch, J.; Quinton, W. L.; Moore, T. R.

    2017-12-01

    Northern permafrost soils store 1035 ± 150 Pg of organic carbon in the first 3 m. In boreal lowlands with warm and thin isolated, sporadic and discontinuous permafrost, increasing temperatures cause a thaw-induced expansion of permafrost-free wetlands at the expense of forested permafrost peat plateaus. Permafrost thaw associated with warmer soils may enhance microbial decomposition of near-surface and deeper organic matter but also increase dissolved organic carbon (DOC) export to aquatic systems. Recent studies suggest that, under a warmer climate, the current net CO2 sink strength of boreal peat landscapes may decline over the next few decades, eventually turning them into net CO2 sources. DOC export from these organic-rich landscapes undergoing rapid permafrost thaw may play a non-negligible role for the carbon budget in a warmer climate. In this study, we quantify the DOC export from a boreal peat landscape in the southern Northwest Territories (Canada). We use half-hourly discharge measurements and DOC concentrations sampled at the outlets of three small catchments ( 0.1 km2) to quantify runoff and DOC export from April to August 2014, 2015 and 2016. We estimate the DOC export contribution to the overall carbon budget using concurrent eddy covariance measurements of net CO2 and methane exchanges. The primary control of DOC export is discharge. In 2016, 70% of the DOC was exported during the two weeks of the spring freshet in early May. DOC export from the three catchments was 3g C m-2 from April to August, which accounted for 15% of the annual net ecosystem exchange. For the same period, the cumulative methane emissions were 6 g C-CH4 m-2. Our findings suggest that thawing boreal peat landscapes along the southern limit of permafrost currently act as net carbon sinks with 11 g C m-2 y-1. Investigating the optical properties of the dissolved organic matter across the different landforms (e.g., transition between forested permafrost peat plateau and permafrost-free wetland) will allow us to assess the different contributions to catchment DOC export and better forecast the changes in DOC lability with permafrost thaw and wetland expansion. Associated with a more rainfall-controlled runoff regime, changes in DOC export with warming may affect the carbon budget in the southern boundaries of the permafrost region.

  11. Influence of weight and type of planting material on fruit quality and its heterogeneity in pineapple [Ananas comosus (L.) Merrill].

    PubMed

    Fassinou Hotegni, V Nicodème; Lommen, Willemien J M; Agbossou, Euloge K; Struik, Paul C

    2014-01-01

    Cultural practices can affect the quality of pineapple fruits and its variation. The objectives of this study were to investigate (a) effects of weight class and type of planting material on fruit quality, heterogeneity in quality and proportion and yield of fruits meeting European export standards, and (b) the improvement in quality, proportion and yield of fruits meeting export standards when flowering was induced at optimum time. Experiments were conducted in Benin with cvs Sugarloaf (a Perola type) and Smooth Cayenne. In cv. Sugarloaf, experimental factors were weight class of planting material (light, mixed, heavy) and time of flowering induction (farmers', optimum) (Experiment 1). In cv. Smooth Cayenne an additional experimental factor was the type of planting material (hapas, ground suckers, a mixture of the two) (Experiment 2). Fruits from heavy planting material had higher infructescence and fruit weights, longer infructescences, shorter crowns, and smaller crown: infructescence length than fruits from light planting material. The type of planting material in Experiment 2 did not significantly affect fruit quality except crown length: fruits from hapas had shorter crowns than those from ground suckers. Crops from heavy planting material had a higher proportion and yield of fruits meeting export standards than those from other weight classes in Experiment 1 only; also the type of planting material in Experiment 2 did not affect these variates. Heterogeneity in fruit quality was usually not reduced by selecting only light or heavy planting material instead of mixing weights; incidentally the coefficient of variation was significantly reduced in fruits from heavy slips only. Heterogeneity was also not reduced by not mixing hapas and ground suckers. Flowering induction at optimum time increased the proportion and yield of fruits meeting export standards in fruits from light and mixed slip weights and in those from the mixture of heavy hapas plus ground suckers.

  12. Influence of weight and type of planting material on fruit quality and its heterogeneity in pineapple [Ananas comosus (L.) Merrill

    PubMed Central

    Fassinou Hotegni, V. Nicodème; Lommen, Willemien J. M.; Agbossou, Euloge K.; Struik, Paul C.

    2015-01-01

    Cultural practices can affect the quality of pineapple fruits and its variation. The objectives of this study were to investigate (a) effects of weight class and type of planting material on fruit quality, heterogeneity in quality and proportion and yield of fruits meeting European export standards, and (b) the improvement in quality, proportion and yield of fruits meeting export standards when flowering was induced at optimum time. Experiments were conducted in Benin with cvs Sugarloaf (a Perola type) and Smooth Cayenne. In cv. Sugarloaf, experimental factors were weight class of planting material (light, mixed, heavy) and time of flowering induction (farmers', optimum) (Experiment 1). In cv. Smooth Cayenne an additional experimental factor was the type of planting material (hapas, ground suckers, a mixture of the two) (Experiment 2). Fruits from heavy planting material had higher infructescence and fruit weights, longer infructescences, shorter crowns, and smaller crown: infructescence length than fruits from light planting material. The type of planting material in Experiment 2 did not significantly affect fruit quality except crown length: fruits from hapas had shorter crowns than those from ground suckers. Crops from heavy planting material had a higher proportion and yield of fruits meeting export standards than those from other weight classes in Experiment 1 only; also the type of planting material in Experiment 2 did not affect these variates. Heterogeneity in fruit quality was usually not reduced by selecting only light or heavy planting material instead of mixing weights; incidentally the coefficient of variation was significantly reduced in fruits from heavy slips only. Heterogeneity was also not reduced by not mixing hapas and ground suckers. Flowering induction at optimum time increased the proportion and yield of fruits meeting export standards in fruits from light and mixed slip weights and in those from the mixture of heavy hapas plus ground suckers. PMID:25653659

  13. An innovative approach for Predicting Farmers' Adaptive Behavior at the Large Watershed Scale: Implications for Water Quality and Crop Yields

    NASA Astrophysics Data System (ADS)

    Valcu-Lisman, A. M.; Gassman, P. W.; Arritt, R. W.; Kling, C.; Arbuckle, J. G.; Roesch-McNally, G. E.; Panagopoulos, Y.

    2017-12-01

    Projected changes in the climatic patterns (higher temperatures, changes in extreme precipitation events, and higher levels of humidity) will affect agricultural cropping and management systems in major agricultural production areas. The concept of adaption to new climatic or economic conditions is an important aspect of the agricultural decision-making process. Adopting cover crops, reduced tillage, extending the drainage systems and adjusting crop management are only a few examples of adaptive actions. These actions can be easily implemented as long as they have private benefits (increased profits, reduced risk). However, each adaptive action has a different impact on water quality. Cover crops and no till usually have a positive impact on water quality, but increased tile drainage typically results in more degraded water quality due primarily to increased export of soluble nitrogen and phosphorus. The goal of this research is to determine the changes in water quality as well in crop yields as farmers undertake these adaptive measures. To answer this research question, we need to estimate the likelihood that these actions will occur, identify the agricultural areas where these actions are most likely to be implemented, and simulate the water quality impacts associated with each of these scenarios. We apply our modeling efforts to the whole Upper-Mississippi River Basin Basin (UMRB) and the Ohio-Tennessee River Basin (OTRB). These two areas are critical source regions for the re-occurring hypoxic zone in the gulf of Mexico. The likelihood of each adaptive agricultural action is estimated using data from a survey conducted in 2012. A large, representative sample of farmers in the Corn Belt was used in the survey to elicit behavioral intentions regarding three of the most important agricultural adaptation strategies (no-till, cover crops and tile drainage). We use these data to study the relationship between intent to adapt, farmer characteristics, farm characteristics, and weather characteristics, and to predict the probability of adoption for each action. Next, we use these estimated probabilities to create different scenarios for the two large scale-watersheds. Finally, we simulate the impact of these scenarios on water quality using calibrated UMRB and OTRB SWAT water quality models.

  14. Environmental Effects on Mesozooplankton Size Structure and Export Flux at Station ALOHA, North Pacific Subtropical Gyre

    NASA Astrophysics Data System (ADS)

    Valencia, Bellineth; Décima, Moira; Landry, Michael R.

    2018-02-01

    Using size-fractionated mesozooplankton biomass data collected over 23 years (1994-2016) of increasing primary production (PP) at station ALOHA (A Long-Term Oligotrophic Habitat Assessment), we evaluate how changing environmental conditions affect mesozooplankton size structure, trophic cycling, and export fluxes in the subtropical North Pacific. From generalized additive model analysis, size structure is significantly influenced by a nonlinear relationship with sea surface temperature that is mainly driven by the strong 1997-1998 El Niño and a positive and linear relationship with PP. Increasing PP has more strongly enhanced the biomass of smaller (0.2-0.5 mm) and larger (>5 mm) mesozooplankton, increasing evenness of the biomass spectra, while animals of 2-5 mm, the major size class for vertically migrating mesozooplankton, show no long-term trend. Measured PP is sufficient to meet feeding requirements that satisfy mesozooplankton respiration and growth rates, as determined by commonly used empirical relationships based on animal size and temperature, consistent with a tightly coupled food web with one intermediate level for protistan consumers. Estimated fecal pellet production suggests an enhanced contribution of mesozooplankton to passive particle export relative to the material collected in 150 m sediment traps. In contrast, the biomass of vertically migrants does not vary systematically with PP due to the varying responses of the different size classes. These results illustrate some complexities in understanding how varying environmental conditions can affect carbon cycling and export processes at the community level in open-ocean oligotrophic systems, which need to be confirmed and better understood by process-oriented mechanistic study.

  15. Cross-ecosystem fluxes: Export of polyunsaturated fatty acids from aquatic to terrestrial ecosystems via emerging insects.

    PubMed

    Martin-Creuzburg, Dominik; Kowarik, Carmen; Straile, Dietmar

    2017-01-15

    Cross-ecosystem fluxes can crucially influence the productivity of adjacent habitats. Emerging aquatic insects represent one important pathway through which freshwater-derived organic matter can enter terrestrial food webs. Aquatic insects may be of superior food quality for terrestrial consumers because they contain high concentrations of essential polyunsaturated fatty acids (PUFA). We quantified the export of PUFA via emerging insects from a midsize, mesotrophic lake. Insects were collected using emergence traps installed above different water depths and subjected to fatty acid analyses. Insect emergence from different depth zones and seasonal mean fatty acid concentrations in different insect groups were used to estimate PUFA fluxes. In total, 80.5mg PUFA m -2 yr -1 were exported, of which 32.8mgm -2 yr -1 were eicosapentaenoic acid (EPA), 7.8mgm -2 yr -1 were arachidonic acid (ARA), and 2.6mgm -2 yr -1 were docosahexaenoic acid (DHA). While Chironomidae contributed most to insect biomass and total PUFA export, Chaoborus flavicans contributed most to the export of EPA, ARA, and especially DHA. The export of total insect biomass from one square meter declined with depth and the timing at which 50% of total insect biomass emerged was correlated with the water depths over which the traps were installed, suggesting that insect-mediated PUFA fluxes are strongly affected by lake morphometry. Applying a conceptual model developed to assess insect deposition rates on land to our insect-mediated PUFA export data revealed an average total PUFA deposition rate of 150mgm -2 yr -1 within 100m inland from the shore. We propose that PUFA export can be reliably estimated using taxon-specific information on emergent insect biomass and seasonal mean body PUFA concentrations of adult insects provided here. Our data indicate that insect-mediated PUFA fluxes from lakes are substantial, implying that freshwater-derived PUFA can crucially influence food web processes in adjacent terrestrial habitats. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Spatial patterns of soil nitrification and nitrate export from forested headwaters in the northeastern United States

    USGS Publications Warehouse

    Ross, D.S.; Shanley, J.B.; Campbell, J.L.; Lawrence, G.B.; Bailey, S.W.; Likens, G.E.; Wemple, B.C.; Fredriksen, G.; Jamison, A.E.

    2012-01-01

    Nitrogen export from small forested watersheds is known to be affected by N deposition but with high regional variability. We studied 10 headwater catchments in the northeastern United States across a gradient of N deposition (5.4 - 9.4 kg ha -1 yr -1) to determine if soil nitrification rates could explain differences in stream water NO 3 - export. Average annual export of two years (October 2002 through September 2004) varied from 0.1 kg NO 3 --N ha -1 yr -1 at Cone Pond watershed in New Hampshire to 5.1 kg ha -1 yr -1 at Buck Creek South in the western Adirondack Mountains of New York. Potential net nitrification rates and relative nitrification (fraction of inorganic N as NO 3 -) were measured in Oa or A soil horizons at 21-130 sampling points throughout each watershed. Stream NO 3 - export was positively related to nitrification rates (r 2 = 0.34, p = 0.04) and the relative nitrification (r 2 = 0.37, p = 0.04). These relationships were much improved by restricting consideration to the 6 watersheds with a higher number of rate measurements (59-130) taken in transects parallel to the streams (r 2 of 0.84 and 0.70 for the nitrification rate and relative nitrification, respectively). Potential nitrification rates were also a better predictor of NO 3 - export when data were limited to either the 6 sampling points closest to the watershed outlet (r 2 = 0.75) or sampling points <250 m from the watershed outlet (r 2 = 0.68). The basal area of conifer species at the sampling plots was negatively related to NO 3 - export. These spatial relationships found here suggest a strong influence of near-stream and near-watershed-outlet soils on measured stream NO 3 - export. Copyright 2012 by the American Geophysical Union.

  17. CD151, a novel host factor of nuclear export signaling in influenza virus infection.

    PubMed

    Qiao, Yongkang; Yan, Yan; Tan, Kai Sen; Tan, Sheryl S L; Seet, Ju Ee; Arumugam, Thiruma Valavan; Chow, Vincent T K; Wang, De Yun; Tran, Thai

    2018-05-01

    Despite advances in our understanding of the mechanisms of influenza A virus (IAV) infection, the crucial virus-host interactions during the viral replication cycle still remain incomplete. Tetraspanin CD151 is highly expressed in the human respiratory tract, but its pathological role in IAV infection is unknown. We sought to characterize the functional role and mechanisms of action of CD151 in IAV infection of the upper and lower respiratory tracts with H1N1 and H3N2 strains. We used CD151-null mice in an in vivo model of IAV infection and clinical donor samples of in vitro-differentiated human nasal epithelial cells cultured at air-liquid interface. As compared with wild-type infected mice, CD151-null infected mice exhibited a significant reduction in virus titer and improvement in survival that is associated with pronounced host antiviral response and inflammasome activation together with accelerated lung repair. Interestingly, we show that CD151 complexes newly synthesized viral proteins with host nuclear export proteins and stabilizes microtubule complexes, which are key processes necessary for the polarized trafficking of viral progeny to the host plasma membrane for assembly. Our results provide new mechanistic insights into our understanding of IAV infection. We show that CD151 is a critical novel host factor of nuclear export signaling whereby the IAV nuclear export uses it to complement its own nuclear export proteins (a site not targeted by current therapy), making this regulation unique, and holds promise for the development of novel alternative/complementary strategies to reduce IAV severity. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  18. RAR Beta: Actions in Prostate Cancer

    DTIC Science & Technology

    2005-04-01

    spermine Nl-acetyltransferase Although prostate cancer can be clinically managed in its (SSAT) regulates the catabolism and export of intracellu- early...in anticancer strategies for spermidine and spermine pools were minimally de- some time (4). Various antagonists such as the ODC inhibitor creased due...Spm, spermine ; SSAT, spermidine/ spermine N’-acetyl- dressed: Dept. of Pharmacology and Therapeutics, Roswell Park Cancer transferase; Tag, SV40 large T

  19. 78 FR 21351 - Orders Granting Authority to Import and Export Natural Gas, To Import Liquefied Natural Gas, To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ...-21-NG AECO GAS STORAGE PARTNERSHIP 13-22-NG OMIMEX CANADA, LTD 13-23-NG AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. SUMMARY: The Office of Fossil Energy (FE... orders are summarized in the attached appendix and may be found on the FE Web site at http://www.fossil...

  20. Utilizing Wetlands for Phosphorus Reduction in Great Lakes Watersheds: A Review of Available Literature Examining Soil Properties and Phosphorus Removal Efficiency

    DTIC Science & Technology

    2017-10-01

    phosphorus inputs in a variety of agricultural and urban settings. However, maximizing the efficiency and benefits of wetlands for phosphorus reduction...39 Appendix B: Citations Related To P In Agricultural Landscapes...priority areas exhibiting high P export rates associated with agricultural and other land use practices (Figure 2). The GLRI Action Plan recommended

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