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Sample records for action approach acaa

  1. A reasoned action approach to health promotion.

    PubMed

    Fishbein, Martin

    2008-01-01

    This article describes the integrative model of behavioral prediction (IM), the latest formulation of a reasoned action approach. The IM attempts to identify a limited set of variables that can account for a considerable proportion of the variance in any given behavior. More specifically, consistent with the original theory of reasoned action, the IM assumes that intentions are the immediate antecedents of behavior, but in addition, the IM recognizes that environmental factors and skills and abilities can moderate the intention-behavior relationship. Similar to the theory of planned behavior, the IM also assumes that intentions are a function of attitudes, perceived normative pressure and self-efficacy, but it views perceived normative pressure as a function of descriptive as well as of injunctive (i.e., subjective) norms. After describing the theory and addressing some of the criticisms directed at a reasoned action approach, the paper illustrates how the theory can be applied to understanding and changing health related behaviors.

  2. Supersymmetric component actions via coset approach

    NASA Astrophysics Data System (ADS)

    Bellucci, S.; Krivonos, S.; Sutulin, A.

    2013-10-01

    We propose a method to construct the on-shell component actions for the theories with 1/2 partial breaking of global supersymmetry within the nonlinear realization (coset) approach. In contrast with the standard superfield approach in which unbroken supersymmetry plays the leading role, we have shifted the attention to the spontaneously broken supersymmetry. It turns out that in the theories in which half of supersymmetries is spontaneously broken, all physical fermions are just the fermions of the nonlinear realization. Moreover, the transformation properties of these fermions with respect to the broken supersymmetry are the same as in the famous Volkov-Akulov model. Just this fact completely fixed all possible appearances of the fermions in the component action: they can enter the action through the determinant of the vielbein (to compensate the transformation of the volume form) and the covariant derivatives, only. It is very important that in our parametrization of the coset the rest of physical components, i.e. all bosonic components, transform as “matter fields” with respect to the broken supersymmetry. Clearly, in such a situation the component action acquires the form of the Volkov-Akulov action for these “matter fields”. The complete form of the action can be further fixed by two additional requirements: (a) to reproduce the bosonic limit, which is explicitly known in many interesting cases, and (b) to have a proper linearized form, which has to be invariant with respect to the linearized unbroken supersymmetry. We supply the general consideration by a detailed example of the component action of N=1 supermembrane in D=4 constructed within our procedure. In this case we provide the exact proof of the invariance of the constructed component action with respect to both, broken and unbroken supersymmetries.

  3. Approaches to local climate action in Colorado

    NASA Astrophysics Data System (ADS)

    Huang, Y. D.

    2011-12-01

    Though climate change is a global problem, the impacts are felt on the local scale; it follows that the solutions must come at the local level. Fortunately, many cities and municipalities are implementing climate mitigation (or climate action) policies and programs. However, they face many procedural and institutional barriers to their efforts, such of lack of expertise or data, limited human and financial resources, and lack of community engagement (Krause 2011). To address the first obstacle, thirteen in-depth case studies were done of successful model practices ("best practices") of climate action programs carried out by various cities, counties, and organizations in Colorado, and one outside Colorado, and developed into "how-to guides" for other municipalities to use. Research was conducted by reading documents (e.g. annual reports, community guides, city websites), email correspondence with program managers and city officials, and via phone interviews. The information gathered was then compiled into a series of reports containing a narrative description of the initiative; an overview of the plan elements (target audience and goals); implementation strategies and any indicators of success to date (e.g. GHG emissions reductions, cost savings); and the adoption or approval process, as well as community engagement efforts and marketing or messaging strategies. The types of programs covered were energy action plans, energy efficiency programs, renewable energy programs, and transportation and land use programs. Between the thirteen case studies, there was a range of approaches to implementing local climate action programs, examined along two dimensions: focus on climate change (whether it was direct/explicit or indirect/implicit) and extent of government authority. This benchmarking exercise affirmed the conventional wisdom propounded by Pitt (2010), that peer pressure (that is, the presence of neighboring jurisdictions with climate initiatives), the level of

  4. Action Research and Organisational Learning: A Norwegian Approach to Doing Action Research in Complex Organisations

    ERIC Educational Resources Information Center

    Eikeland, Olav

    2012-01-01

    The purpose of this article is to present a specific approach to the practice of action research "in complex organisations". Clearly, there are many approaches to the challenge of doing action research in organisations; approaches that are, and also must be, quite context dependent and specific. But my purpose is neither to give an…

  5. The Action Competence Approach in Environmental Education

    ERIC Educational Resources Information Center

    Jensen, Bjarne Bruun; Schnack, Karsten

    2006-01-01

    In this article, the concept of action competence is presented and an attempt is made to locate it within the concept of general educational theory. The concept of action competence, it is argued, should occupy a central position in the theory of environmental education as many of the crucial educational problems concerning a political liberal…

  6. Doing Educational Research: An Action Research Approach.

    ERIC Educational Resources Information Center

    Otto, Alice; Nkanga, S.

    1995-01-01

    An American teaching anesthesiology in Tanzania sought help from a member of the host culture in order to grasp cultural meanings underpinning medical education practices, using action research to develop and refine research methods and solve problems related to the need to accommodate culturally diverse students' learning needs. (SM)

  7. Towards actionable risk stratification: a bilinear approach.

    PubMed

    Wang, Xiang; Wang, Fei; Hu, Jianying; Sorrentino, Robert

    2015-02-01

    Risk stratification is instrumental to modern clinical decision support systems. Comprehensive risk stratification should be able to provide the clinicians with not only the accurate assessment of a patient's risk but also the clinical context to be acted upon. However, existing risk stratification techniques mainly focus on predicting the risk score for individual patients; at the cohort level, they offer little insight beyond a flat score-based segmentation. This essentially reduces a patient to a score and thus removes him/her from his/her clinical context. To address this limitation, in this paper we propose a bilinear model for risk stratification that simultaneously captures the three key aspects of risk stratification: (1) it predicts the risk of each individual patient; (2) it stratifies the patient cohort based on not only the risk score but also the clinical characteristics; and (3) it embeds all patients into clinical contexts with clear interpretation. We apply our model to a cohort of 4977 patients, 1127 among which were diagnosed with Congestive Heart Failure (CHF). We demonstrate that our model cannot only accurately predict the onset risk of CHF but also provide rich and actionable clinical insights into the patient cohort.

  8. A New Approach for Resolving Conflicts in Actionable Behavioral Rules

    PubMed Central

    Zhu, Dan; Zeng, Daniel

    2014-01-01

    Knowledge is considered actionable if users can take direct actions based on such knowledge to their advantage. Among the most important and distinctive actionable knowledge are actionable behavioral rules that can directly and explicitly suggest specific actions to take to influence (restrain or encourage) the behavior in the users' best interest. However, in mining such rules, it often occurs that different rules may suggest the same actions with different expected utilities, which we call conflicting rules. To resolve the conflicts, a previous valid method was proposed. However, inconsistency of the measure for rule evaluating may hinder its performance. To overcome this problem, we develop a new method that utilizes rule ranking procedure as the basis for selecting the rule with the highest utility prediction accuracy. More specifically, we propose an integrative measure, which combines the measures of the support and antecedent length, to evaluate the utility prediction accuracies of conflicting rules. We also introduce a tunable weight parameter to allow the flexibility of integration. We conduct several experiments to test our proposed approach and evaluate the sensitivity of the weight parameter. Empirical results indicate that our approach outperforms those from previous research. PMID:25162054

  9. TOPICAL REVIEW: Effective action of vacuum: the semiclassical approach

    NASA Astrophysics Data System (ADS)

    Shapiro, Ilya L.

    2008-05-01

    We present a brief, and to a great extent, pedagogical, review on renormalization in curved spacetime and some recent results on the derivation and better understanding of quantum corrections to the action of gravity. The paper is mainly devoted to the semiclassical approach, but we also discuss its importance for quantum gravity and string theory.

  10. Evaluating Action Learning: A Critical Realist Complex Network Theory Approach

    ERIC Educational Resources Information Center

    Burgoyne, John G.

    2010-01-01

    This largely theoretical paper will argue the case for the usefulness of applying network and complex adaptive systems theory to an understanding of action learning and the challenge it is evaluating. This approach, it will be argued, is particularly helpful in the context of improving capability in dealing with wicked problems spread around…

  11. A Participatory Action Research Approach To Evaluating Inclusive School Programs.

    ERIC Educational Resources Information Center

    Dymond, Stacy K.

    2001-01-01

    This article proposes a model for evaluating inclusive schools. Key elements of the model are inclusion of stakeholders in the evaluation process through a participatory action research approach, analysis of program processes and outcomes, use of multiple methods and measures, and obtaining perceptions from diverse stakeholder groups. (Contains…

  12. Supporting prison nurses: an action research approach to education.

    PubMed

    Bennett, Clare; Perry, Jane; Lapworth, Tracy; Davies, Judith; Preece, Vicky

    Since April 2006, commissioning responsibility for healthcare services in public prisons has been fully devolved to NHS primary care trusts (PCTs), with the expectation that offenders will have access to the same range and quality of health services available to the wider population. In order to support prison nurses in meeting this goal, a PCT and university established a partnership, which used an action research approach to develop, instigate and evaluate a bespoke educational programme for nurses working in two local prisons. This article outlines the processes involved in the design and implementation of the programme. It also reports on findings from pre- and post-intervention questionnaires and focus groups with course participants, and semi-structured interviews with key stakeholders, which suggest that the innovation had a positive impact on the nurses' confidence, assertiveness, clinical expertise and approach to change. The article concludes that the action research project should continue, but its scope should now broaden to address educational support for healthcare assistants, collaborative learning between prison officers and prison nurses, and the implementation of clinical supervision and action learning sets.

  13. Entrainment and motor emulation approaches to joint action: Alternatives or complementary approaches?

    PubMed Central

    Colling, Lincoln J.; Williamson, Kellie

    2014-01-01

    Joint actions, such as music and dance, rely crucially on the ability of two, or more, agents to align their actions with great temporal precision. Within the literature that seeks to explain how this action alignment is possible, two broad approaches have appeared. The first, what we term the entrainment approach, has sought to explain these alignment phenomena in terms of the behavioral dynamics of the system of two agents. The second, what we term the emulator approach, has sought to explain these alignment phenomena in terms of mechanisms, such as forward and inverse models, that are implemented in the brain. They have often been pitched as alternative explanations of the same phenomena; however, we argue that this view is mistaken, because, as we show, these two approaches are engaged in distinct, and not mutually exclusive, explanatory tasks. While the entrainment approach seeks to uncover the general laws that govern behavior the emulator approach seeks to uncover mechanisms. We argue that is possible to do both and that the entrainment approach must pay greater attention to the mechanisms that support the behavioral dynamics of interest. In short, the entrainment approach must be transformed into a neuroentrainment approach by adopting a mechanistic view of explanation and by seeking mechanisms that are implemented in the brain. PMID:25309403

  14. Action Research: An Approach for the Teachers in Higher Education

    ERIC Educational Resources Information Center

    Yasmeen, G.

    2008-01-01

    Introduction: Action Research is a formative study of progress commonly practiced by teachers in schools. Basically an action research is a spiral process that includes problem investigation, taking action & fact-finding about the result of action. It enables a teacher to adopt/craft most appropriate strategy within its own teaching…

  15. Action Research: An Approach for the Teachers in Higher Education

    ERIC Educational Resources Information Center

    Yasmeen, Ghazala

    2008-01-01

    Introduction: Action Research is a formative study of progress commonly practiced by teachers in schools. Basically an action research is a spiral process that includes problem investigation, taking action & fact-finding about the result of action. It enables a teacher to adopt/craft most appropriate strategy within its own teaching environment.…

  16. Aquatic ecosystem condition: The Fraser River Action Plan approach

    SciTech Connect

    Tuominen, T.; Raymond, B.; Sekela, M.; Reynoldson, T.

    1995-12-31

    A major goal of the Canadian government`s Fraser River Action Plan (FRAP) is to clean up existing pollution problems in the Fraser River Basin. In support of this goal, the Environmental Quality Assessment Program is assessing the quality of the aquatic environment, particularly with respect to contaminants. The program, conducted from 1993 to 1998, is to establish a baseline condition for the aquatic ecosystem against which the success of clean up efforts can be measured. The FRAP approach is to use a combination of contaminant exposure or stressor indicators and organism ``effects`` indicators. The focus is on three components of the aquatic ecosystem: (1) bed sediment, (2) resident fish and (3) benthos. A priority for the program is integration of the three components, wherever possible. Bed sediments, as indicators of contaminant stress, are sampled at fourteen reaches in the river and major tributaries. Two species of resident fish are sampled and analyzed for condition factors, enzyme induction, histopathology and contaminant content at each of nine sites in the basin. The resident fish data are providing a measure of contaminant exposure and effect. Organism community effects will be assessed by a study which is classifying approximately 200 tributary and mainstem sites based on benthos community structure. For the first time in a large river system in Canada, this benthos study uses a multivariate approach which relates a suite of chemical and physical characteristics to benthos community structure.

  17. Affirmative Action in Higher Education: Three Approaches to the Issue.

    ERIC Educational Resources Information Center

    Noel, Melvina

    Affirmative action remains one of the most controversial of social policies in complex democracies. Altman and Promise (1995), in their article entitled "Affirmative Action: The Law of Unintended Consequences," focuses on the phenomenon that almost every action of government, no matter how well intentioned, has unexpected results. They suggest…

  18. Action Learning for Professionals: A New Approach to Practice

    ERIC Educational Resources Information Center

    Abbott, Christine; Mayes, Cathy

    2014-01-01

    Following on from the article "Building Capacity in Social Care: An Evaluation of a National Programme of Action Learning Facilitator Development" (Abbott, C., L. Burtney, and C. Wall. 2013. "Action Learning: Research & Practice" 10 (2): 168--177), this article describes how action learning is being introduced in Cornwall…

  19. Multi-action planning for threat management: a novel approach for the spatial prioritization of conservation actions.

    PubMed

    Cattarino, Lorenzo; Hermoso, Virgilio; Carwardine, Josie; Kennard, Mark J; Linke, Simon

    2015-01-01

    Planning for the remediation of multiple threats is crucial to ensure the long term persistence of biodiversity. Limited conservation budgets require prioritizing which management actions to implement and where. Systematic conservation planning traditionally assumes that all the threats in priority sites are abated (fixed prioritization approach). However, abating only the threats affecting the species of conservation concerns may be more cost-effective. This requires prioritizing individual actions independently within the same site (independent prioritization approach), which has received limited attention so far. We developed an action prioritization algorithm that prioritizes multiple alternative actions within the same site. We used simulated annealing to find the combination of actions that remediate threats to species at the minimum cost. Our algorithm also accounts for the importance of selecting actions in sites connected through the river network (i.e., connectivity). We applied our algorithm to prioritize actions to address threats to freshwater fish species in the Mitchell River catchment, northern Australia. We compared how the efficiency of the independent and fixed prioritization approach varied as the importance of connectivity increased. Our independent prioritization approach delivered more efficient solutions than the fixed prioritization approach, particularly when the importance of achieving connectivity was high. By spatially prioritizing the specific actions necessary to remediate the threats affecting the target species, our approach can aid cost-effective habitat restoration and land-use planning. It is also particularly suited to solving resource allocation problems, where consideration of spatial design is important, such as prioritizing conservation efforts for highly mobile species, species facing climate change-driven range shifts, or minimizing the risk of threats spreading across different realms.

  20. Approach and withdrawal actions modulate the startle reflex independent of affective valence and muscular effort.

    PubMed

    Thibodeau, Ryan

    2011-07-01

    The startle reflex is modulated during processing of pleasant and unpleasant affective cues. One explanation of this finding contends that approach and withdrawal motivational processes are key to explaining the effect. Undergraduates performed arm flexion and arm extension actions shown elsewhere to reliably elicit approach and withdrawal motives, respectively. Results showed that arm extension (a withdrawal action) was associated with the largest startles, followed by a neutral control action and arm flexion (an approach action). This pattern was not attributable to the subjective pleasantness or muscular effort associated with the actions. Results support motivational priming accounts of startle reflex modulation.

  1. Fostering Adolescents' Coping Skills--An Action Approach.

    ERIC Educational Resources Information Center

    Israelshvili, Moshe

    2002-01-01

    Discusses the implementation of action theory with adolescents in Israel making the transition to military life. Suggests that action theory offers a comprehensive strategy for counseling persons who are confronting a stressful episode in life through a more detailed and socially embedded collaboration between the counselor, client, and peers.…

  2. An Information-Based Approach to Action Understanding

    ERIC Educational Resources Information Center

    Ramenzoni, Veronica C.; Riley, Michael A.; Shockley, Kevin; Davis, Tehran

    2008-01-01

    It has been proposed that the ability to make sense of other agents' behavior relies on the activation of internal mechanisms that map action perception onto action execution. In this study we explored the constraints on this ability introduced by eyeheight-scaled information in the optic array. Short and tall participants provided maximum…

  3. Developing Entrepreneurial Graduates: An Action-Learning Approach.

    ERIC Educational Resources Information Center

    Jones-Evans, Dylan; Williams, William; Deacon, Jonathan

    2000-01-01

    Describes development and marketing of a Welsh business school's diploma in entrepreneurial practice, an action learning-based program. Discusses problems encountered in dealing with the concept of business ambiguity, program flexibility, and measurement of outcomes. (SK)

  4. Loop expansion of the average effective action in the functional renormalization group approach

    NASA Astrophysics Data System (ADS)

    Lavrov, Peter M.; Merzlikin, Boris S.

    2015-10-01

    We formulate a perturbation expansion for the effective action in a new approach to the functional renormalization group method based on the concept of composite fields for regulator functions being their most essential ingredients. We demonstrate explicitly the principal difference between the properties of effective actions in these two approaches existing already on the one-loop level in a simple gauge model.

  5. Energy Conservation Education. An Action Approach. Grades 4-9.

    ERIC Educational Resources Information Center

    Zamm, Michael; Samuel, Barry C.

    Seventeen lessons are provided in this curriculum designed to involve students (grades 4-9) in energy conservation. The lessons are presented in four parts. The three lessons in part I are intended to give students a preliminary conceptual framework for energy conservation and to motivate them to participate in the conservation-action projects…

  6. Educational Poetics: An Aesthetic Approach to Action Research

    ERIC Educational Resources Information Center

    Gitlin, Andrew; Peck, Marcie

    2008-01-01

    In this article, Gitlin and Peck argue that much of the development of action research has been based on a reconstructed view of science (i.e., a science that is more contextual, less law-like, less causal, but still accurately represents reality and is teacher centered as opposed to researcher centered). In contrast to this reconstructed view of…

  7. Environmental Education in Action: A Discursive Approach to Curriculum Design

    ERIC Educational Resources Information Center

    Reis, Giuliano; Roth, Wolff-Michael

    2007-01-01

    Why do the designers of environmental education do what they do towards the environment through education? More importantly, how do they account for their design decisions (plans and actions)? Using the theoretical and methodological framework of discourse analysis, we analyse environmental education designers' discourse in terms of the discursive…

  8. A Collaborative Action Research Approach to Professional Learning

    ERIC Educational Resources Information Center

    Bleicher, Robert E.

    2014-01-01

    The field of professional development is moving towards the notion of professional learning, highlighting the active learning role that teachers play in changing their knowledge bases, beliefs and practice. This article builds on this idea and argues for creating professional learning that is guided by a collaborative action research (CAR)…

  9. Understanding approach and avoidance in verbal descriptions of everyday actions: An ERP study.

    PubMed

    Marrero, Hipólito; Urrutia, Mabel; Beltrán, David; Gámez, Elena; Díaz, José M

    2017-02-13

    Understanding verbal descriptions of everyday actions could involve the neural representation of action direction (avoidance and approach) toward persons and things. We recorded the electrophysiological activity of participants while they were reading approach/avoidance action sentences that were directed toward a target: a thing/a person (i.e., "Petra accepted/rejected Ramón in her group"/ "Petra accepted/rejected the receipt of the bank"). We measured brain potentials time locked to the target word. In the case of things, we found a N400-like component with right frontal distribution modulated by approach/avoidance action. This component was more negative in avoidance than in approach sentences. In the case of persons, a later negative event-related potential (545-750 ms) with left frontal distribution was sensitive to verb direction, showing more negative amplitude for approach than avoidance actions. In addition, more negativity in approach-person sentences was associated with fear avoidance trait, whereas less negativity in avoidance-person sentences was associated with a greater approach trait. Our results support that verbal descriptions of approach/avoidance actions are encoded differently depending on whether the target is a thing or a person. Implications of these results for a social, emotional and motivational understanding of action language are discussed.

  10. Testing the independent action hypothesis of plant pathogen mode of action: a simple and powerful new approach.

    PubMed

    Zwart, Mark P; Elena, Santiago F

    2015-01-01

    The independent action hypothesis is a simple model of pathogen infection that can make many useful predictions on infection kinetics and, therefore, a number of different tests of independent action have been developed. However, some of these analyses are rather sophisticated, limiting their appeal to experimentalists, and it is also unclear how well the different tests perform. Here, we developed and evaluated a simple and robust new test of independent action. Our new test is based on using a constant inoculum dose of one pathogen variant, varying the dose of a second variant, and then quantifying the infection response for the first variant. We simulated infection data in which we introduced deviations from independent action, experimental variation, or both. Simulations showed that our new procedure has many advantages over the existing tests of independent action, especially if only systemic-infection data are available. We also performed experimental tests of our new procedure using two marked Tobacco etch virus (TEV) variants. We found minor deviations from the independent action model, which were not detected by previous tests using existing methods, exemplifying the utility of this approach. We discuss the implications for TEV infection kinetics and consider how to reconcile different dose-dependent effects.

  11. A Trans-Actional Approach to Moral Development

    ERIC Educational Resources Information Center

    Pamental, Matthew

    2010-01-01

    Among the latest trends in moral educational theory, several authors have suggested that a sociocultural approach to moral education is an improvement over the dominant cognitive-developmental and character educational paradigms. This approach draws its inspiration from the work of the Russian psychologist Lev Vygotsky. In the 1920s, Vygotsky…

  12. Chapter 14. Approaches for Evaluation of Mode of Action.

    EPA Science Inventory

    Cellular and molecular approaches vastly expand the possibilities for revealing the underlying mechanisms of developmental toxicity. The typical teratology screening test examines near-term fetuses after exposure throughout organogenesis and evaluates the potential for an exposur...

  13. Demonstrating and Evaluating an Action Learning Approach to Building Project Management Competence

    NASA Technical Reports Server (NTRS)

    Kotnour, Tim; Starr, Stan; Steinrock, T. (Technical Monitor)

    2001-01-01

    This paper contributes a description of an action-learning approach to building project management competence. This approach was designed, implemented, and evaluated for use with the Dynacs Engineering Development Contract at the Kennedy Space Center. The aim of the approach was to improve three levels of competence within the organization: individual project management skills, project team performance. and organizational capabilities such as the project management process and tools. The overall steps to the approach, evaluation results, and lessons learned are presented. Managers can use this paper to design a specific action-learning approach for their organization.

  14. Multiple emotions: a person-centered approach to the relationship between intergroup emotion and action orientation.

    PubMed

    Fernando, Julian W; Kashima, Yoshihisa; Laham, Simon M

    2014-08-01

    Although a great deal of research has investigated the relationship between emotions and action orientations, most studies to date have used variable-centered techniques to identify the best emotion predictor(s) of a particular action. Given that people frequently report multiple or blended emotions, a profitable area of research may be to adopt person-centered approaches to examine the action orientations elicited by a particular combination of emotions or "emotion profile." In two studies, across instances of intergroup inequality in Australia and Canada, we examined participants' experiences of six intergroup emotions: sympathy, anger directed at three targets, shame, and pride. In both studies, five groups of participants with similar emotion profiles were identified by cluster analysis and their action orientations were compared; clusters indicated that the majority of participants experienced multiple emotions. Each action orientation was also regressed on the six emotions. There were a number of differences in the results obtained from the person-centered and variable-centered approaches. This was most apparent for sympathy: the group of participants experiencing only sympathy showed little inclination to perform prosocial actions, yet sympathy was a significant predictor of numerous action orientations in regression analyses. These results imply that sympathy may only prompt a desire for action when experienced in combination with other emotions. We suggest that the use of person-centered and variable-centered approaches as complementary analytic strategies may enrich research into not only the affective predictors of action, but emotion research in general.

  15. Understanding Nature-Related Behaviors among Children through a Theory of Reasoned Action Approach

    ERIC Educational Resources Information Center

    Gotch, Chad; Hall, Troy

    2004-01-01

    The Theory of Reasoned Action has proven to be a valuable tool for predicting and understanding behavior and, as such, provides a potentially important basis for environmental education program design. This study used a Theory of Reasoned Action approach to examine a unique type of behavior (nature-related activities) and a unique population…

  16. Entrepreneurs in Action: An Integrated Approach to Problem Solving Via the Internet.

    ERIC Educational Resources Information Center

    Clouse, R. Wilburn; Goodin, Terry; Davey, Mark; Burgoyne, Jeff

    A new curricular approach called Entrepreneurs in Action! was developed to encourage development of entrepreneurial thinking, including thinking "outside of a structured setting" and demonstrating creativity in problem solving. The effects of the Entrepreneurs in Action! program on the development of entrepreneurial thinking among…

  17. The Methods of Teaching Course Based on Constructivist Learning Approach: An Action Research

    ERIC Educational Resources Information Center

    Altun, Sertel; Yücel-Toy, Banu

    2015-01-01

    This purpose of this study is to investigate how the course designed based on constructivist principles has been implemented, what actions have been taken to solve problems and what thoughts have arisen in the minds of teacher candidates with regard to the constructivist learning approach. In this study, an action research was employed which…

  18. Action-perception coupling in kinesthesia: a new approach.

    PubMed

    Feldman, Anatol G; Ilmane, Nabil; Sangani, Samir; Raptis, Helli; Esmailzadeh, Nima

    2013-11-01

    According to recent findings, intentional motor actions are controlled by resetting the referent position, R, at which neuromuscular elements, including reflexes, begin to act. It is suggested that somatosensory afferents inform the brain about the deviation (P) of body segments from the centrally set referent position. To perceive the actual position (Q) of body segments and form the position sense (PS), the central and afferent signals are combined: Q=R+P. In previous studies, the R has been shown to remain invariant during involuntary changes in the wrist position elicited by sudden unloading of muscles, suggesting that only the afferent component is responsible for the PS during this reflex. In contrast, the central PS component, R, is predominantly responsible for PS during intentional motion in isotonic conditions. We tested the hypothesis that the R and P are interchangeable PS components such that involuntary changes in wrist position elicited by the unloading reflex can easily be reproduced by making intentional changes in wrist position in isotonic conditions, in the absence of vision. The PS rule also suggests that PS is independent of sense of effort, which was tested by asking subjects to reproduce elbow joint angles under different constant loads. We also tested the hypothesis that tendon vibration may elicit motion that may not be perceived by subjects (no-motion illusion). These hypotheses were confirmed in three experiments. It is concluded that the R and P are additive components of PS and that, contrary to the conventional view, PS is independent of the sense of effort or efference copy. The PS rule also explains kinesthetic illusions and the phantom limb phenomenon. This study advances the understanding of action-perception coupling in kinesthesia.

  19. Writers Develop Skills through Collaboration: An Action Research Approach

    ERIC Educational Resources Information Center

    Ferguson-Patrick, Kate

    2007-01-01

    Collaborative approaches designed to increase writing productivity (amount written) as well as writing quality were implemented over a period of six months with a small group of 12 six-year-olds in a Primary School in Newcastle, NSW, Australia. The study demonstrated the positive nature of peer interactions with an increase in quality and…

  20. A Youth Development Approach to Evaluation: Critical Participatory Action Research

    ERIC Educational Resources Information Center

    Zeller-Berkman, Sarah; Muñoz-Proto, Carolina; Torre, María Elena

    2015-01-01

    Across the U.S., youth development approaches are being tested in out-of-school time programs as a strategy to combat the growing opportunity gap between privileged and underprivileged youth (Gardner, Roth, & Brooks-Gunn, 2009). Along with increased recognition of the value of youth development programming has come increased financial support…

  1. Location estimation of approaching objects is modulated by the observer's inherent and momentary action capabilities.

    PubMed

    Kandula, Manasa; Hofman, Dennis; Dijkerman, H Chris

    2016-08-01

    Action capability may be one of the factors that can influence our percept of the world. A distinction can be made between momentary action capability (action capability at that particular moment) and inherent action capability (representing a stable action capability). In the current study, we investigated whether there was a biasing effect of these two forms of action capability on visual perception of location. In a virtual reality room, subjects had to stop a moving ball from hitting a pillar. On some trials, the ball disappeared automatically during its motion. Subjects had to estimate the location of the ball's disappearance in these trials. We expected that if action is necessary but action capability (inherent or momentary) is limiting performance, the location of approaching objects with respect to the observer is underestimated. By judging the objects to be nearer than they really are, the need to select and execute the appropriate action increases, thereby facilitating quick action (Cole et al. in Psychol Sci 24(1):34-40, 2013. doi: 10.1177/0956797612446953 ). As a manipulation of inherent action capability in a virtual environment, two groups of participants (video game players vs. non-video game players) were entered into the study (high and low action capability). Momentary action capability was manipulated by using two difficulty levels in the experiment (Easy vs. Difficult). Results indicated that inherent and momentary action capabilities interacted together to influence online location judgments: Non-players underestimated locations when the task was Difficult. Taken together, our data suggest that both inherent and momentary action capabilities influence location judgments.

  2. An integrated approach for vascular health: a call to action.

    PubMed

    O'Neill, Blair J; Rana, Shadab N; Bowman, Vincent

    2015-01-01

    Vascular diseases such as stroke, myocardial infarction, most causes of heart failure, dementia, peripheral arterial disease, certain kidney, and many lung and eye conditions are a result of disorders in the blood vessels (large and small) throughout the entire human body. Vascular diseases are the leading cause of preventable death and disability in Canada. Most vascular diseases share common risk factors (high blood pressure, diabetes, dyslipidemia, and obesity), which can be influenced by modifiable health behaviours such as unhealthy diet, smoking, lack of physical activity, and stress. Ninety percent of Canadians face an increased risk, which could be modified by managing these health behaviours and risk factors. Canada's aging population, combined with alarming trends in obesity, physical inactivity, high blood pressure, and diabetes are expected to further increase the social and economic effect of vascular diseases in the coming decades, unless there are major changes in health policy. Even more concerning is the increase in vascular risk factors among Canada's youth, and ethnically diverse populations. Vascular diseases affect not only the patient, but also place burdens on their spouses, families, friends, and communities. Tremendous potential exists to reduce the effects of vascular diseases through healthy public policy, supporting Canadians to make healthy lifestyle changes, and coordinating efforts across the continuum of care in a patient-focused manner. Vascular health requires partnerships for action across many sectors including government, health care practitioners, academia, not-for-profit organizations, and the private sector. The health sector alone cannot solve this problem.

  3. Process Algebra Approach for Action Recognition in the Maritime Domain

    NASA Technical Reports Server (NTRS)

    Huntsberger, Terry

    2011-01-01

    The maritime environment poses a number of challenges for autonomous operation of surface boats. Among these challenges are the highly dynamic nature of the environment, the onboard sensing and reasoning requirements for obeying the navigational rules of the road, and the need for robust day/night hazard detection and avoidance. Development of full mission level autonomy entails addressing these challenges, coupled with inference of the tactical and strategic intent of possibly adversarial vehicles in the surrounding environment. This paper introduces PACIFIC (Process Algebra Capture of Intent From Information Content), an onboard system based on formal process algebras that is capable of extracting actions/activities from sensory inputs and reasoning within a mission context to ensure proper responses. PACIFIC is part of the Behavior Engine in CARACaS (Cognitive Architecture for Robotic Agent Command and Sensing), a system that is currently running on a number of U.S. Navy unmanned surface and underwater vehicles. Results from a series of experimental studies that demonstrate the effectiveness of the system are also presented.

  4. Translating science into action: periodontal health through public health approaches.

    PubMed

    Jürgensen, Nanna; Petersen, Poul E; Ogawa, Hiroshi; Matsumoto, Sayaka

    2012-10-01

    -directed actions in prevention of periodontal disease is most unusual. The high need for reorientation of periodontal research toward public health is discussed in this report as well as the responsibilities of oral health organizations, research institutions and health authorities.

  5. Approaching the Bad and Avoiding the Good: Lateral Prefrontal Cortical Asymmetry Distinguishes between Action and Valence

    PubMed Central

    Berkman, Elliot T.; Lieberman, Matthew D.

    2011-01-01

    Goal pursuit in humans sometimes involves approaching unpleasant and avoiding pleasant stimuli, such as when a dieter chooses to eat vegetables (although he does not like them) instead of doughnuts (which he greatly prefers). Previous neuroscience investigations have established a left–right prefrontal asymmetry between approaching pleasant and avoiding unpleasant stimuli, but these investigations typically do not untangle the roles of action motivation (approach vs. avoidance) and stimulus valence (pleasant vs. unpleasant) in this asymmetry. Additionally, studies on asymmetry have been conducted almost exclusively using electroencephalography and have been difficult to replicate using functional magnetic resonance imaging (fMRI). The present fMRI study uses a novel goal pursuit task that separates action motivation from stimulus valence and a region-of-interest analysis approach to address these limitations. Results suggest that prefrontal asymmetry is associated with action motivation and not with stimulus valence. Specifically, there was increased left (vs. right) activation in dorsolateral prefrontal cortex during approach (vs. avoidance) actions regardless of the stimulus valence, but no such effect was observed for pleasant compared to unpleasant stimuli. This asymmetry effect during approach–avoidance action motivations occurred in the dorsolateral but not orbito-frontal aspects of prefrontal cortex. Also, individual differences in approach–avoidance motivation moderated the effect such that increasing trait approach motivation was associated with greater left-sided asymmetry during approach actions (regardless of the stimulus valence). Together, these results support the notion that prefrontal asymmetry is associated with action motivation regardless of stimulus valence and, as such, might be linked with goal pursuit processes more broadly. PMID:19642879

  6. Improving the Process of Career Decision Making: An Action Research Approach

    ERIC Educational Resources Information Center

    Greenbank, Paul

    2011-01-01

    Purpose: This study adopts an action research approach with the aim of improving the process of career decision making among undergraduates in a business school at a "new" university in the UK. Design/methodology/approach: The study utilised unfreezing techniques, multiple case studies in conjunction with the principle of analogical…

  7. The quench action approach in finite integrable spin chains

    NASA Astrophysics Data System (ADS)

    Alba, Vincenzo; Calabrese, Pasquale

    2016-04-01

    We consider the problem of constructing the stationary state following a quantum quench, using the exact overlaps for finite size integrable models. We focus on the isotropic Heisenberg spin chain with initial state Néel or Majumdar-Ghosh (dimer), although the proposed approach is valid for an arbitrary integrable model. We consider only eigenstates which do not contain zero-momentum strings because the latter are affected by fictitious singularities that are very difficult to take into account. We show that the fraction of eigenstates that do not contain zero-momentum strings is vanishing in the thermodynamic limit. Consequently, restricting to this part of the Hilbert space leads to vanishing expectation values of local observables. However, it is possible to reconstruct the asymptotic values by properly reweighting the expectations in the considered subspace, at the price of introducing finite-size corrections. We also develop a Monte Carlo sampling of the Hilbert space which allows us to study larger systems. We accurately reconstruct the expectation values of the conserved charges and the root distributions in the stationary state, which turn out to match the exact thermodynamic results. The proposed method can be implemented even in cases in which an analytic thermodynamic solution is not obtainable.

  8. Simplified approach for calculating moments of action for linear reaction-diffusion equations.

    PubMed

    Ellery, Adam J; Simpson, Matthew J; McCue, Scott W; Baker, Ruth E

    2013-11-01

    The mean action time is the mean of a probability density function that can be interpreted as a critical time, which is a finite estimate of the time taken for the transient solution of a reaction-diffusion equation to effectively reach steady state. For high-variance distributions, the mean action time underapproximates the critical time since it neglects to account for the spread about the mean. We can improve our estimate of the critical time by calculating the higher moments of the probability density function, called the moments of action, which provide additional information regarding the spread about the mean. Existing methods for calculating the nth moment of action require the solution of n nonhomogeneous boundary value problems which can be difficult and tedious to solve exactly. Here we present a simplified approach using Laplace transforms which allows us to calculate the nth moment of action without solving this family of boundary value problems and also without solving for the transient solution of the underlying reaction-diffusion problem. We demonstrate the generality of our method by calculating exact expressions for the moments of action for three problems from the biophysics literature. While the first problem we consider can be solved using existing methods, the second problem, which is readily solved using our approach, is intractable using previous techniques. The third problem illustrates how the Laplace transform approach can be used to study coupled linear reaction-diffusion equations.

  9. Streamlined approach for environmental restoration plan for corrective action unit 416, Mud Pit, Project Shoal Area

    SciTech Connect

    1997-07-01

    This plan addresses the actions necessary for the restoration and closure of the Project Shoal Area (PSA), Surface Corrective Action Unit (CAU) 416, Mud Pit (Corrective Action Site No. 57-09-01), a pit that was used to store effluent produced during drilling of the Post-Shot Borehole PS-1 in 1963. This plan describes the activities that will occur at the site and the steps that will be taken to gather enough data to obtain a notice of completion from the Nevada Division of Environmental Protection (NDEP). This plan was prepared under the Streamlined Approach for Environmental Restoration (SAFER) concept, and it will be implemented with the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996) and the Industrial Sites Quality Assurance Project Plan (DOE/NV, 1994). The SAFER process is being employed at this CAU where enough information exists about the nature and extent of contamination to propose an appropriate corrective action without completing a Corrective Action Decision Document and Corrective Action Plan. This process combines elements of the Data Quality Objective (DQO) process and the observational approach to help plan and conduct corrective actions. DQOs are used to identify the problem and define the type and quality of data needed to complete the investigation phase of the process. This has already been completed for the mud pit so it will not be repeated here. The DQOs for the mud pit are presented in the Corrective Action Investigation Plan for Project Shoal Area, CAU No. 416 (DOE/NV, 1996). This observational approach provides a framework for managing uncertainty and planning decision making.

  10. Sustainable Participation in Regular Exercise amongst Older People: Developing an Action Research Approach

    ERIC Educational Resources Information Center

    Davies, Jeanne; Lester, Carolyn; O'Neill, Martin; Williams, Gareth

    2008-01-01

    Objective: This article describes the Triangle Project's work with a post industrial community, where healthy living activities were developed in response to community members' expressed needs. Method: An action research partnership approach was taken to reduce health inequalities, with local people developing their own activities to address…

  11. Using a Reasoned Action Approach to Examine US College Women's Intention to Get the HPV Vaccine

    ERIC Educational Resources Information Center

    Jozkowski, Kristen N.; Geshnizjani, Alireza

    2016-01-01

    Objective: Although at high risk of contracting the human papillomavirus (HPV), less than one-half of US college women have been vaccinated. The purpose of this study was to identify underlying factors influencing college women's intention to get the HPV vaccine via developing an instrument using the Reasoned Action Approach (RAA). Setting: Data…

  12. The Action--Reflection--Modelling (ARM) Pedagogical Approach for Teacher Education: A Malaysia-UK Project

    ERIC Educational Resources Information Center

    Jarvis, Joy; Dickerson, Claire; Thomas, Kit; Graham, Sally

    2014-01-01

    This article presents the Action--Reflection--Modelling (ARM) pedagogical approach for teacher education developed during a Malaysia-UK collaborative project to construct a Bachelor of Education (Honours) degree programme in Primary Mathematics, with English and Health and Physical Education as minor subjects. The degree programme was written…

  13. The Art and Science of Rain Barrels: A Service Learning Approach to Youth Watershed Action

    ERIC Educational Resources Information Center

    Rector, Patricia; Lyons, Rachel; Yost, Theresa

    2013-01-01

    Using an interdisciplinary approach to water resource education, 4-H Youth Development and Environmental Extension agents enlisted 4-H teens to connect local watershed education with social action. Teens participated in a dynamic service learning project that included learning about nonpoint source pollution; constructing, decorating, and teaching…

  14. Improving "At-Action" Decision-Making in Team Sports through a Holistic Coaching Approach

    ERIC Educational Resources Information Center

    Light, Richard L.; Harvey, Stephen; Mouchet, Alain

    2014-01-01

    This article draws on Game Sense pedagogy and complex learning theory (CLT) to make suggestions for improving decision-making ability in team sports by adopting a holistic approach to coaching with a focus on decision-making "at-action". It emphasizes the complexity of decision-making and the need to focus on the game as a whole entity,…

  15. Christian Faculty Teaching Reflective Practice: An Action Research Approach to Learning

    ERIC Educational Resources Information Center

    Wong, Arch Chee Keen

    2009-01-01

    The article reports the final results of a collaborative action research project that devised a reflective approach to theological education. This project lives within the tension between prescribing and implementing a model of theological education and working at the level of applied understanding. Living within this tension are six professors in…

  16. One School's Approach to Overcoming Resistance and Improving Appraisal: Organizational Learning in Action

    ERIC Educational Resources Information Center

    Piggot-Irvine, Eileen

    2010-01-01

    This article reports on the action research (AR) approach adopted by one New Zealand (NZ) primary school to review and improve its appraisal system. Historically the staff had demonstrated considerable negativity towards appraisal. The classic reconnaissance, implementation and evaluation phases of AR were adopted by the case study school as a…

  17. Action Research as an Approach to Integrating Sustainability into MBA Programs: An Exploratory Study

    ERIC Educational Resources Information Center

    Benn, Suzanne; Dunphy, Dexter

    2009-01-01

    This article reports on an exploratory project that employed an action research approach to integrating sustainability into core subjects in the MBA program at an Australian university. It documents the change methodology used, the theoretical basis for this choice, and the project outcomes. It then identifies some key enabling factors and…

  18. Collaborative Group Action Research: A Constructivist Approach to Developing an Integrated Curriculum.

    ERIC Educational Resources Information Center

    Saurino, Penny L.; Saurino, Dan R.

    Elementary teachers collaborated on a research project that investigated how a constructivist approach to gifted and talented integrated curriculum strategies and techniques could be developed and implemented. The collaborative group action research cycle involved planning, collecting baseline data, intervening strategies/modifying interventions,…

  19. The Kaleidoscope of Voices: An Action Research Approach to Informing Institutional e-Learning Policy

    ERIC Educational Resources Information Center

    Roushan, Gelareh; Holley, Debbie; Biggins, David

    2016-01-01

    This paper describes a two-spiral action research approach (AR) in its analysis of the experience of a British University endeavouring to change and reposition itself in the context of fast pace external change in terms of innovation. Taking the European Union (EU) 2020 digital competence framework (Ferrari 2013), with its drive to address the…

  20. Linking Action Learning and Inter-Organisational Learning: The Learning Journey Approach

    ERIC Educational Resources Information Center

    Schumacher, Thomas

    2015-01-01

    The article presents and illustrates the learning journey (LJ)--a new management development approach to inter-organisational learning based on observation, reflection and problem-solving. The LJ involves managers from different organisations and applies key concepts of action learning and systemic organisational development. Made up of…

  1. Assessing a Controversial In-Service Program: An Action Research Approach.

    ERIC Educational Resources Information Center

    Kapel, David E.

    A course was prepared by Planned Parenthood on the subject of human sexuality. The school district required an evaluation to determine effects, assess whether the instructional agency should be invited back, and to determine whether experiences should be continued. An action research approach was deemed appropriate. The objectives of the research…

  2. Rethinking Approaches to Working with Children Who Challenge: Action Learning for Emancipatory Practice

    ERIC Educational Resources Information Center

    MacNaughton, Glenda; Hughes, Patrick; Smith, Kylie

    2007-01-01

    This article describes an action-learning project that helped teachers to rethink their approaches to children who challenge. The project enabled and encouraged teachers to reflect critically on why and how particular children challenged them and then to use their critical reflections to strengthen their capacity to work with those children. The…

  3. Science and Social Practice: Action Research and Activity Theory as Socio-Critical Approaches

    ERIC Educational Resources Information Center

    Langemeyer, Ines

    2011-01-01

    Action research and activity theory are considered by a number of followers as socio-critical approaches, whereas others do not relate them to social-criticism and use them merely as methods to improve practice. This article searches for general insights in Kurt Lewin's and Lev S. Vygotsky's work into how one proceeds and acts critically. In their…

  4. Learning to Be Interdisciplinary: An Action Research Approach to Boundary Spanning

    ERIC Educational Resources Information Center

    Munoz, Karen; Jeris, Laurel

    2005-01-01

    Objective: This study explored challenges and barriers that need to be addressed in a preprofessional educational setting to provide opportunities for boundary spanning that leads to family-centred interdisciplinary service provision. Design: The design employed in this study was participatory action research, an inductive approach. Setting: The…

  5. The Action Competence Approach and the "New" Discourses of Education for Sustainable Development, Competence and Quality Criteria

    ERIC Educational Resources Information Center

    Mogensen, Finn; Schnack, Karsten

    2010-01-01

    Action competence has been a key concept in educational circles in Denmark since the 1980s. This paper explores the relationship between the action competence approach and recent discourses of education for sustainable development (ESD), competence and quality criteria. First we argue that action competence is an educational ideal, referring to…

  6. ACAA fly ash basics: quick reference card

    SciTech Connect

    2006-07-01

    Fly ash is a fine powdery material created when coal is burned to generate electricity. Before escaping into the environment via the utility stacks, the ash is collected and may be stored for beneficial uses or disposed of, if necessary. The use of fly ash provides environmental benefits, such as the conservation of natural resources, the reduction of greenhouse gas emissions and eliminating the needed for ash disposal in landfills. It is also a valuable mineral resource that is used in construction and manufacturing. Fly ash is used in the production of Portland cement, concrete, mortars and stuccos, manufactured aggregates along with various agricultural applications. As mineral filler, fly ash can be used for paints, shingles, carpet backing, plastics, metal castings and other purposes. This quick reference card is intended to provide the reader basic source, identification and composition, information specifically related to fly ash.

  7. In action or inaction? Social approach-avoidance tendencies in major depression.

    PubMed

    Radke, Sina; Güths, Franziska; André, Julia A; Müller, Bernhard W; de Bruijn, Ellen R A

    2014-11-30

    In depression, approach deficits often impair everyday social functioning, but empirical findings on performance-based measurements of approach-avoidance behavior remain conflicting. To investigate action tendencies in patients with depression, the current study used an explicit version of the Approach-Avoidance Task (AAT). In this task, participants responded to emotional faces by either pulling a joystick toward (approach) or pushing it away from themselves (avoid). Reaction times to happy and angry expressions with direct and averted gaze were assessed in 30 patients with major depressive disorder and 20 matched healthy controls. In contrast to healthy individuals, depressed patients did not show approach-avoidance tendencies, i.e., there was no dominant behavioral tendency and they reacted to happy and angry expressions likewise. These results indicate that behavioral adjustments to different emotional expressions, gaze directions or motivational demands were lacking in depression. Crucially, this distinguishes depressed patients not only from healthy individuals, but also from other clinical populations that demonstrate aberrant approach-avoidance tendencies, e.g., patients with social anxiety or psychopathy. As responding flexibly to different social signals is integral to social interactions, the absence of any social motivational tendencies seems maladaptive, but may also provide opportunities for modifying action tendencies in a therapeutic context.

  8. Building policy capacities: an interactive approach for linking knowledge to action in health promotion.

    PubMed

    Rütten, Alfred; Gelius, Peter

    2014-09-01

    This article outlines a theoretical framework for an interactive, research-driven approach to building policy capacities in health promotion. First, it illustrates how two important issues in the recent public health debate, capacity building and linking scientific knowledge to policy action, are connected to each other theoretically. It then introduces an international study on an interactive approach to capacity building in health promotion policy. The approach combines the ADEPT model of policy capacities with a co-operative planning process to foster the exchange of knowledge between policy-makers and researchers, thus improving intra- and inter-organizational capacities. A regional-level physical activity promotion project involving governmental and public-law institutions, NGOs and university researchers serves as a case study to illustrate the potential of the approach for capacity building. Analysis and comparison with a similar local-level project indicate that the approach provides an effective means of linking scientific knowledge to policy action and to planning concrete measures for capacity building in health promotion, but that it requires sufficiently long timelines and adequate resources to achieve adequate implementation and sustainability.

  9. Emergence of self and other in perception and action: an event-control approach.

    PubMed

    Jordan, J Scott

    2003-12-01

    The present paper analyzes the regularities referred to via the concept 'self.' This is important, for cognitive science traditionally models the self as a cognitive mediator between perceptual inputs and behavioral outputs. This leads to the assertion that the self causes action. Recent findings in social psychology indicate this is not the case and, as a consequence, certain cognitive scientists model the self as being epiphenomenal. In contrast, the present paper proposes an alternative approach (i.e., the event-control approach) that is based on recently discovered regularities between perception and action. Specifically, these regularities indicate that perception and action planning utilize common neural resources. This leads to a coupling of perception, planning, and action in which the first two constitute aspects of a single system (i.e., the distal-event system) that is able to pre-specify and detect distal events. This distal-event system is then coupled with action (i.e., effector-control systems) in a constraining, as opposed to 'causal' manner. This model has implications for how we conceptualize the manner in which one infers the intentions of another, anticipates the intentions of another, and possibly even experiences another. In conclusion, it is argued that it may be possible to map the concept 'self' onto the regularities referred to in the event-control model, not in order to reify 'the self' as a causal mechanism, but to demonstrate its status as a useful concept that refers to regularities that are part of the natural order.

  10. Exploring teacher's perceptions of concept mapping as a teaching strategy in science: An action research approach

    NASA Astrophysics Data System (ADS)

    Marks Krpan, Catherine Anne

    In order to promote science literacy in the classroom, students need opportunities in which they can personalize their understanding of the concepts they are learning. Current literature supports the use of concept maps in enabling students to make personal connections in their learning of science. Because they involve creating explicit connections between concepts, concept maps can assist students in developing metacognitive strategies and assist educators in identifying misconceptions in students' thinking. The literature also notes that concept maps can improve student achievement and recall. Much of the current literature focuses primarily on concept mapping at the secondary and university levels, with limited focus on the elementary panel. The research rarely considers teachers' thoughts and ideas about the concept mapping process. In order to effectively explore concept mapping from the perspective of elementary teachers, I felt that an action research approach would be appropriate. Action research enabled educators to debate issues about concept mapping and test out ideas in their classrooms. It also afforded the participants opportunities to explore their own thinking, reflect on their personal journeys as educators and play an active role in their professional development. In an effort to explore concept mapping from the perspective of elementary educators, an action research group of 5 educators and myself was established and met regularly from September 1999 until June 2000. All of the educators taught in the Toronto area. These teachers were interested in exploring how concept mapping could be used as a learning tool in their science classrooms. In summary, this study explores the journey of five educators and myself as we engaged in collaborative action research. This study sets out to: (1) Explore how educators believe concept mapping can facilitate teaching and student learning in the science classroom. (2) Explore how educators implement concept

  11. An application of the health action process approach to physiotherapy rehabilitation adherence.

    PubMed

    Clark, Heather; Bassett, Sandra

    2014-11-01

    This study tested the utility of an extended version of the health action process approach (HAPA) to explain the attitudinal and behavioural processes contributing to rehabilitation adherence and ultimately rehabilitation outcomes in physiotherapy patients. The HAPA focuses on self-efficacy, action and coping planning and their relationships to behavioural intentions and actual behaviour. A one group prospective design was employed in which 20 participants with soft tissue injuries of the shoulder were followed for the first four weeks of their clinic- and home-based physiotherapy. Participants enrolled in the study after their first physiotherapy clinic appointment, at which time they completed questionnaires measuring the motivational HAPA constructs and shoulder function. Action and coping plans were then made with assistance of the researcher. Adherence behaviours were measured throughout the study, and at the end the volitional stage HAPA constructs, action self-efficacy and shoulder function were assessed. Moderate to strong correlations occurred between the self-efficacies and behavioural intentions, behavioural intentions and adherence behaviours, and adherence behaviours and post-study shoulder function. These findings support the extension of the HAPA model to include the functional outcomes for soft tissue injuries of the shoulder. Its true value will nevertheless only be realized in a longer duration study with a larger sample size.

  12. Corrective action unit modeling approach for the underground test area, Nevada Test Site, Nye County, Nevada

    SciTech Connect

    1998-03-01

    The modeling approach serves as a template for the development, application, and interpretation of the Corrective Action Unit (CAU) - scale saturated groundwater flow and transport model (herein called the CAU model) to be used for forecasting radionuclide migration in all Nevada Test Site (NTS) CAUs, consistent with the Federal Facility Agreement and Consent Order (FFACO) and Underground Test Area (UGTA) strategy. A summary of the project background, the FFACO and strategy, and the roles of participating agencies, is provided followed by a description of the contents of the document.

  13. 76 FR 54288 - Notice of Final Federal Agency Actions on Proposed Bridge and Approach Roadways in Nevada and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Bridge and Approach... Federal agencies that are final within the meaning of 23 U.S.C. 139(I)(1). The actions relate to the proposed Laughlin-Bullhead City Bridge project in Laughlin, Clark County, Nevada; and in Bullhead...

  14. Potential of an outranking multi-criteria approach to support the participatory assessment of land management actions.

    PubMed

    Ocampo-Melgar, Anahí; Bautista, Susana; Edward deSteiguer, J; Orr, Barron J

    2016-12-07

    We evaluated the potential of an outranking Multi-Criteria Decision Analysis approach for assisting in the participatory assessment of dryland management actions implemented in the San Simon watershed, in southeastern Arizona, USA. We compared an outranking-facilitated assessment of actions with a simple and direct (baseline) ranking of the same actions by the participating stakeholders in terms of: 1) internal homogeneity of each assessment approach, (2) similarity of individual assessments between methods, and (3) effects of the use of implicit/explicit assessment criteria. The actions assessed combined various management approaches, including livestock management (rotation, resting), vegetation management (grass seeding, brush control), and hydraulic structures (dams, dykes). The outranking-facilitated assessment discriminated better between actions and reduced the variability of results between individual stakeholders as compared with the direct ranking of actions. In general, the two assessments significantly differed in the relative preference of the five management actions assessed, yet both assessments identified rotational grazing combined with vegetation management (grass seeding and brush control) as the most preferred management action in the study area. The comparative analysis revealed inconsistencies between the use of implicit and explicit assessment criteria. Our findings highlight the opportunities offered by outranking approaches to help capture, structure, and make explicit stakeholder perspectives in the framework of a participatory environmental assessment process, which may facilitate the understanding of the multiple preferences involved. The outranking integration process, which resembles a voting procedure, proved simple and transparent, with potential for contributing to stakeholder engagement and trust in participatory assessment.

  15. Supporting organizational learning: a comparative approach to evaluation in action research.

    PubMed

    Livesey, Heather; Challender, Shelia

    2002-05-01

    For well over a decade, the organizational context of nursing in the United Kingdom has been one of change and reform with a policy shift towards primary and community led health care. Such a major shift in policy provides nurses with an opportunity to re-think their approaches towards the individuals and communities they serve in order to promote self-care, recognize achievable health goals and provide family and community support. Although there is a growing appreciation of action research as an useful approach to this kind of development, it can be difficult to evaluate published studies because of the diverse nature of the literature. This paper will present and evaluate two case studies using a particular conceptual device (The Normative Information Model-based Systems Analysis and Design) in order to explore a possible alternative to the interpretative narrative or positivistic hypothesis-testing models used to report other kinds of nursing research and enlarge the debate about process evaluation.

  16. Wider Action Plan and Multidisciplinar Approach Could Be a Wining Idea in Creation of Friendly Environment

    PubMed Central

    Gojkovic-Bukvic, Natasa; Bukvic, Nenad

    2012-01-01

    Herein, we proposed planning of wide transdisciplinary actions, which bring a solution for economic activity such as transportation, strongly related to pollution output with possible repercussions on climate change and public health. To solve logistics problem by introduction of common intermodal policy, and creation of more friendly transport solution, it is possible to obtain sustainable development, climate change prevention, government policy, and regulation which are all related to human health and creation of health-supportive environment. This approach permits environmental and biological monitoring same as economic results measurement by key performance indicators. This approach implementing emerging scientific knowledge in environmental health science such as genetic epidemiology aimed at understanding how genomic variation impacts phenotypic expression and how genes interact with the environment at the population level with subsequent translation into practical information for clinicians as well as for public health policy creation. PMID:22496704

  17. Development of a Wheelchair Skills Home Program for Older Adults Using a Participatory Action Design Approach

    PubMed Central

    Giesbrecht, Edward M.; Miller, William C.; Mitchell, Ian M.; Woodgate, Roberta L.

    2014-01-01

    Restricted mobility is the most common impairment among older adults and a manual wheelchair is often prescribed to address these limitations. However, limited access to rehabilitation services results in older adults typically receiving little or no mobility training when they receive a wheelchair. As an alternative and novel approach, we developed a therapist-monitored wheelchair skills home training program delivered via a computer tablet. To optimize efficacy and adherence, principles of self-efficacy and adult learning theory were foundational in the program design. A participatory action design approach was used to engage older adult wheelchair users, care providers, and prescribing clinicians in an iterative design and development process. A series of prototypes were fabricated and revised, based on feedback from eight stakeholder focus groups, until a final version was ready for evaluation in a clinical trial. Stakeholder contributions affirmed and enhanced the foundational theoretical principles and provided validation of the final product for the target population. PMID:25276768

  18. Hamilton Jacobi approach for first order actions and theories with higher derivatives

    NASA Astrophysics Data System (ADS)

    Bertin, M. C.; Pimentel, B. M.; Pompeia, P. J.

    2008-03-01

    In this work, we analyze systems described by Lagrangians with higher order derivatives in the context of the Hamilton-Jacobi formalism for first order actions. Two different approaches are studied here: the first one is analogous to the description of theories with higher derivatives in the hamiltonian formalism according to [D.M. Gitman, S.L. Lyakhovich, I.V. Tyutin, Soviet Phys. J. 26 (1983) 730; D.M. Gitman, I.V. Tyutin, Quantization of Fields with Constraints, Springer-Verlag, New York, Berlin, 1990] the second treats the case where degenerate coordinate are present, in an analogy to reference [D.M. Gitman, I.V. Tyutin, Nucl. Phys. B 630 (2002) 509]. Several examples are analyzed where a comparison between both approaches is made.

  19. Wider action plan and multidisciplinar approach could be a wining idea in creation of friendly environment.

    PubMed

    Gojkovic-Bukvic, Natasa; Bukvic, Nenad

    2012-01-01

    Herein, we proposed planning of wide transdisciplinary actions, which bring a solution for economic activity such as transportation, strongly related to pollution output with possible repercussions on climate change and public health. To solve logistics problem by introduction of common intermodal policy, and creation of more friendly transport solution, it is possible to obtain sustainable development, climate change prevention, government policy, and regulation which are all related to human health and creation of health-supportive environment. This approach permits environmental and biological monitoring same as economic results measurement by key performance indicators. This approach implementing emerging scientific knowledge in environmental health science such as genetic epidemiology aimed at understanding how genomic variation impacts phenotypic expression and how genes interact with the environment at the population level with subsequent translation into practical information for clinicians as well as for public health policy creation.

  20. Development of a wheelchair skills home program for older adults using a participatory action design approach.

    PubMed

    Giesbrecht, Edward M; Miller, William C; Mitchell, Ian M; Woodgate, Roberta L

    2014-01-01

    Restricted mobility is the most common impairment among older adults and a manual wheelchair is often prescribed to address these limitations. However, limited access to rehabilitation services results in older adults typically receiving little or no mobility training when they receive a wheelchair. As an alternative and novel approach, we developed a therapist-monitored wheelchair skills home training program delivered via a computer tablet. To optimize efficacy and adherence, principles of self-efficacy and adult learning theory were foundational in the program design. A participatory action design approach was used to engage older adult wheelchair users, care providers, and prescribing clinicians in an iterative design and development process. A series of prototypes were fabricated and revised, based on feedback from eight stakeholder focus groups, until a final version was ready for evaluation in a clinical trial. Stakeholder contributions affirmed and enhanced the foundational theoretical principles and provided validation of the final product for the target population.

  1. Experimental Semiotics: A New Approach For Studying Communication As A Form Of Joint Action

    PubMed Central

    Galantucci, Bruno

    2015-01-01

    In the last few years, researchers have begun to investigate the emergence of novel forms of human communication in the laboratory. I survey this growing line of research, which may be called experimental semiotics, from three distinct angles. First, I situate the new approach in its theoretical and historical context. Second, I review a sample of studies that exemplify experimental semiotics. Third, I present an empirical study that illustrates how the new approach can help us understand the sociocognitive underpinnings of human communication. The main conclusion of the paper will be that, by reproducing micro samples of historical processes in the laboratory, experimental semiotics offers new powerful tools for investigating human communication as a form of joint action. PMID:25164941

  2. Hamilton-Jacobi approach for first order actions and theories with higher derivatives

    SciTech Connect

    Bertin, M.C. Pimentel, B.M. Pompeia, P.J.

    2008-03-15

    In this work, we analyze systems described by Lagrangians with higher order derivatives in the context of the Hamilton-Jacobi formalism for first order actions. Two different approaches are studied here: the first one is analogous to the description of theories with higher derivatives in the hamiltonian formalism according to [D.M. Gitman, S.L. Lyakhovich, I.V. Tyutin, Soviet Phys. J. 26 (1983) 730; D.M. Gitman, I.V. Tyutin, Quantization of Fields with Constraints, Springer-Verlag, New York, Berlin, 1990] the second treats the case where degenerate coordinate are present, in an analogy to reference [D.M. Gitman, I.V. Tyutin, Nucl. Phys. B 630 (2002) 509]. Several examples are analyzed where a comparison between both approaches is made.

  3. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 496: Buried Rocket Site, Antelope Lake, Tonopah Test Range

    SciTech Connect

    U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Bechtel Nevada

    2004-05-01

    This Streamlined Approach for Environmental Restoration (SAFER) plan details the activities necessary to close Corrective Action Unit 496: Buried Rocket Site, Antelope Lake. CAU 496 consists of one site located at the Tonopah Test Range, Nevada.

  4. A New Approach for Assessing Aquifer Sustainability and the Impact of Proposed Management Actions

    NASA Astrophysics Data System (ADS)

    Butler, J. J., Jr.; Whittemore, D. O.; Wilson, B. B.

    2015-12-01

    Aquifers are under stress worldwide as a result of large imbalances between inflows and outflows. These imbalances are particularly severe in aquifers in semi-arid regions that are heavily pumped for irrigation, such as the High Plains aquifer (HPA) in the United States. The water resources community has responded by placing an increasing emphasis on more sustainable management plans. To aid in the formulation of such plans, we have developed a simple, water-balance-based approach for rapid assessment of the impact of proposed management actions and the prospects for aquifer sustainability. This theoretically sound approach is particularly well suited for assessing the short- to medium-term (years to a few decades) response to management actions in seasonably pumped aquifers. The net inflow (capture) term of the aquifer water balance can also be directly calculated from water-level and water-use data with this approach. Application to the data-rich portion of the HPA in the state of Kansas reveals that practically achievable reductions in annual pumping would have a large impact. For example, a 22% reduction in average annual water use would have stabilized areally averaged water levels across northwest Kansas from 1996 to 2013 because of larger-than-expected and near-constant net inflows. Whether this is a short-term phenomenon or a path to long-term sustainability, however, has yet to be determined. Water resources managers are often in a quandary about the most effective use of scarce funds for data collection in support of aquifer assessment and management activities. This work demonstrates that a strong emphasis should be placed on collection of reliable water-use data; greater resources devoted to direct measurement of pumping will yield deeper insights into an aquifer's future. The Kansas HPA is similar to many other regional aquifers supporting critically needed agricultural production, so this approach should prove of value far beyond the borders of Kansas.

  5. Action versus Result-Oriented Schemes in a Grassland Agroecosystem: A Dynamic Modelling Approach

    PubMed Central

    Sabatier, Rodolphe; Doyen, Luc; Tichit, Muriel

    2012-01-01

    Effects of agri-environment schemes (AES) on biodiversity remain controversial. While most AES are action-oriented, result-oriented and habitat-oriented schemes have recently been proposed as a solution to improve AES efficiency. The objective of this study was to compare action-oriented, habitat-oriented and result-oriented schemes in terms of ecological and productive performance as well as in terms of management flexibility. We developed a dynamic modelling approach based on the viable control framework to carry out a long term assessment of the three schemes in a grassland agroecosystem. The model explicitly links grazed grassland dynamics to bird population dynamics. It is applied to lapwing conservation in wet grasslands in France. We ran the model to assess the three AES scenarios. The model revealed the grazing strategies respecting ecological and productive constraints specific to each scheme. Grazing strategies were assessed by both their ecological and productive performance. The viable control approach made it possible to obtain the whole set of viable grazing strategies and therefore to quantify the management flexibility of the grassland agroecosystem. Our results showed that habitat and result-oriented scenarios led to much higher ecological performance than the action-oriented one. Differences in both ecological and productive performance between the habitat and result-oriented scenarios were limited. Flexibility of the grassland agroecosystem in the result-oriented scenario was much higher than in that of habitat-oriented scenario. Our model confirms the higher flexibility as well as the better ecological and productive performance of result-oriented schemes. A larger use of result-oriented schemes in conservation may also allow farmers to adapt their management to local conditions and to climatic variations. PMID:22496746

  6. A Mean Field Approach to Self-Organization in Spatially Extended Perception-Action and Psychological Systems

    NASA Astrophysics Data System (ADS)

    Frank, Till; Beek, Peter

    It is argued that perception-action systems should be considered as spatially extended systems on account of (i) the presence of spatially distributed synchronized brain activity during the performance of perceptual-motor tasks, and (ii) the failure of conventional zero-dimensional theoretical approaches to deal with multistable perception-action systems and hysteresis in the presence of noise. It is shown that in spatially extended systems self-organization can arise due to the emergence of mean field attractors. This mean field approach is exemplified for a particular class of perception-action systems, namely, rhythmic movements. In addition, clinical implications of the mean field approach and the notion of spatially extended perception-action systems are briefly discussed in the context of psychotherapy and Parkinson's disease.

  7. Two-particle irreducible effective action approach to nonlinear current-conserving approximations in driven systems.

    PubMed

    Peralta-Ramos, J; Calzetta, E

    2009-05-27

    Using closed-time-path two-particle irreducible coarse-grained effective action (CTP 2PI CGEA) techniques, we study the response of an open interacting electronic system to time-dependent external electromagnetic fields. We show that the CTP 2PI CGEA is invariant under a simultaneous gauge transformation of the external field and the full Schwinger-Keldysh propagator, and that this property holds even when the loop expansion of the CTP 2PI CGEA is truncated at arbitrary order. The effective action approach provides a systematic way of calculating the propagator and response functions of the system, via the Schwinger-Dyson equation and the Bethe-Salpeter equations, respectively. We show that, due to the invariance of the CTP 2PI CGEA under external gauge transformations, the response functions calculated from it satisfy the Ward-Takahashi hierarchy, thus warranting the conservation of the electronic current beyond the expectation value level. We also clarify the connection between nonlinear response theory and the WT hierarchy, and discuss an example of an ad hoc approximation that violates it. These findings may be useful in the study of current fluctuations in correlated electronic pumping devices.

  8. Risk newsboy: approach for addressing uncertainty in developing action levels and cleanup limits

    SciTech Connect

    Cooke, Roger; MacDonell, Margaret

    2007-07-01

    Site cleanup decisions involve developing action levels and residual limits for key contaminants, to assure health protection during the cleanup period and into the long term. Uncertainty is inherent in the toxicity information used to define these levels, based on incomplete scientific knowledge regarding dose-response relationships across various hazards and exposures at environmentally relevant levels. This problem can be addressed by applying principles used to manage uncertainty in operations research, as illustrated by the newsboy dilemma. Each day a newsboy must balance the risk of buying more papers than he can sell against the risk of not buying enough. Setting action levels and cleanup limits involves a similar concept of balancing and distributing risks and benefits in the face of uncertainty. The newsboy approach can be applied to develop health-based target concentrations for both radiological and chemical contaminants, with stakeholder input being crucial to assessing 'regret' levels. Associated tools include structured expert judgment elicitation to quantify uncertainty in the dose-response relationship, and mathematical techniques such as probabilistic inversion and iterative proportional fitting. (authors)

  9. Teaching Writing Skills Based on a Genre Approach to L2 Primary School Students: An Action Research

    ERIC Educational Resources Information Center

    Ahn, Hyejeong

    2012-01-01

    This article, based on research findings, examines the effect of implementing a genre approach to develop writing competency of Year 5 and 6 L2 primary school students. Using action research, the genre approach was implemented over a 10-week term with two lessons per week in a culturally and linguistically diverse ESL class in a South Australian…

  10. Assessing Ethanol's Actions in the Suprachiasmatic Circadian Clock Using In vivo and In vitro Approaches

    PubMed Central

    2014-01-01

    Research over the past decade has demonstrated substantial interactions between the circadian system and the processes through which alcohol affects behavior and physiology. Here we summarize the results of our collaborative efforts focused on this intersection. Using a combination of in vivo and in vitro approaches, we have shown that ethanol affects many aspects of the mammalian circadian system, both acutely as well as after chronic administration. Conversely, we have shown circadian influences on ethanol consumption. Importantly, we are beginning to delve into the cellular mechanisms associated with these effects. We are also starting to form a picture of the neuroanatomical bases for many of these actions. Finally, we put our current findings into perspective by suggesting new avenues of inquiry for our future efforts. PMID:25457753

  11. Improving the accuracy of admitted subacute clinical costing: an action research approach.

    PubMed

    Hakkennes, Sharon; Arblaster, Ross; Lim, Kim

    2016-08-29

    Objective The aim of the present study was to determine whether action research could be used to improve the breadth and accuracy of clinical costing data in an admitted subacute settingMethods The setting was a 100-bed in-patient rehabilitation centre. Using a pre-post study design all admitted subacute separations during the 2011-12 financial year were eligible for inclusion. An action research framework aimed at improving clinical costing methodology was developed and implemented.Results In all, 1499 separations were included in the study. A medical record audit of a random selection of 80 separations demonstrated that the use of an action research framework was effective in improving the breadth and accuracy of the costing data. This was evidenced by a significant increase in the average number of activities costed, a reduction in the average number of activities incorrectly costed and a reduction in the average number of activities missing from the costing, per episode of care.Conclusions Engaging clinicians and cost centre managers was effective in facilitating the development of robust clinical costing data in an admitted subacute setting. Further investigation into the value of this approach across other care types and healthcare services is warranted.What is known about this topic? Accurate clinical costing data is essential for informing price models used in activity-based funding. In Australia, there is currently a lack of robust admitted subacute cost data to inform the price model for this care type.What does this paper add? The action research framework presented in this study was effective in improving the breadth and accuracy of clinical costing data in an admitted subacute setting.What are the implications for practitioners? To improve clinical costing practices, health services should consider engaging key stakeholders, including clinicians and cost centre managers, in reviewing clinical costing methodology. Robust clinical costing data has the

  12. Realizing human rights-based approaches for action on the social determinants of health.

    PubMed

    Rasanathan, Kumanan; Norenhag, Johanna; Valentine, Nicole

    2010-12-15

    Health inequities are clear evidence of violations of the right to health. Yet despite this common ground, action on the social determinants of health aiming to reduce health inequities is sometimes disconnected from implementation of human rights-based approaches. This is explained in part by differing histories, disciplines, and epistemologies. The capacity of human rights instruments to alter policies on social determinants can seem limited. An absolutist focus on individuals and processes can seem at odds with the attention to differences in population health outcomes central to the concern for health equity. However, developments in rights-based approaches have seen the terrain of human rights increasingly address social determinants. Human rights provide a firm legal basis for tackling the inequities in power and resources that the Commission on Social Determinants of Health identifies as fundamental to achieving health equity. Indicators and benchmarks developed for rights-based approaches to health systems can be developed further within health sectors and translated to other sectors and disciplines. The discourse and evidence base of social determinants can also contribute to implementing rights-based approaches, as its resultant policy momentum can provide essential levers to realize the right to health. Therefore, there is no clear-cut delineation between the human rights and health equity movements, and both may constructively work together to realize their goals. Such constructive collaboration will not prove straightforward; it will, instead, require profound engagement and innovations in both theory and practice. Yet this effort represents an important opportunity for those who seek social justice in health.

  13. A Structural Approach to Performance Monitoring of Waste Sites: Obtaining Actionable Information

    NASA Astrophysics Data System (ADS)

    Mattson, E. D.; Versteeg, R.; Ankeny, M.; Richardson, A.

    2005-05-01

    Both government and non-government agencies are faced with the challenge of long-term monitoring of waste sites and landfills. Such monitoring should provide actionable information on how these sites are evolving, including (but not limited to) information on the success of remedial treatment methods (either active or passive), compliance with regulatory standards, and evolution of system behavior associated with these sites. Current monitoring efforts suffer from the lack of integration between data collection, data management, information extraction and information use. An alternative to such efforts is the use of a structural approach to performance monitoring developed at Idaho National Laboratory (INL). This approach has the following characteristics (1) tight integration between monitoring objectives and data collection efforts (2) well structured storage of all relevant monitoring data (3) establishment of transparent, reproducible procedures for translation of data to information (including coupling of data to models) (4) development of a web based interface to the monitoring system, providing easy access to data and results by multiple stakeholders. We will discuss several examples of the implementation of the INL monitoring system, including an EPA superfund site and several landfill sites.

  14. A Mode-of-Action Approach for the Identification of Genotoxic Carcinogens

    PubMed Central

    Hernández, Lya G.; van Benthem, Jan; Johnson, George E.

    2013-01-01

    Distinguishing between clastogens and aneugens is vital in cancer risk assessment because the default assumption is that clastogens and aneugens have linear and non-linear dose-response curves, respectively. Any observed non-linearity must be supported by mode of action (MOA) analyses where biological mechanisms are linked with dose-response evaluations. For aneugens, the MOA has been well characterised as disruptors of mitotic machinery where chromosome loss via micronuclei (MN) formation is an accepted endpoint used in risk assessment. In this study we performed the cytokinesis-block micronucleus assay and immunofluorescence mitotic machinery visualisation in human lymphoblastoid (AHH-1) and Chinese Hamster fibroblast (V79) cell lines after treatment with the aneugen 17-β-oestradiol (E2). Results were compared to previously published data on bisphenol-A (BPA) and Rotenone data. Two concentration-response approaches (the threshold-[Td] and benchmark-dose [BMD] approaches) were applied to derive a point of departure (POD) for in vitro MN induction. BMDs were also derived from the most sensitive carcinogenic endpoint. Ranking comparisons of the PODs from the in vitro MN and the carcinogenicity studies demonstrated a link between these two endpoints for BPA, E2 and Rotenone. This analysis was extended to include 5 additional aneugens, 5 clastogens and 3 mutagens and further concentration and dose-response correlations were observed between PODs from the in vitro MN and carcinogenicity. This approach is promising and may be further extended to other genotoxic carcinogens, where MOA and quantitative information from the in vitro MN studies could be used in a quantitative manner to further inform cancer risk assessment. PMID:23675539

  15. The quantitation of buffering action II. Applications of the formal & general approach

    PubMed Central

    Schmitt, Bernhard M

    2005-01-01

    Background The paradigm of "buffering" originated in acid-base physiology, but was subsequently extended to other fields and is now used for a wide and diverse set of phenomena. In the preceding article, we have presented a formal and general approach to the quantitation of buffering action. Here, we use that buffering concept for a systematic treatment of selected classical and other buffering phenomena. Results H+ buffering by weak acids and "self-buffering" in pure water represent "conservative buffered systems" whose analysis reveals buffering properties that contrast in important aspects from classical textbook descriptions. The buffering of organ perfusion in the face of variable perfusion pressure (also termed "autoregulation") can be treated in terms of "non-conservative buffered systems", the general form of the concept. For the analysis of cytoplasmic Ca++ concentration transients (also termed "muffling"), we develop a related unit that is able to faithfully reflect the time-dependent quantitative aspect of buffering during the pre-steady state period. Steady-state buffering is shown to represent the limiting case of time-dependent muffling, namely for infinitely long time intervals and infinitely small perturbations. Finally, our buffering concept provides a stringent definition of "buffering" on the level of systems and control theory, resulting in four absolute ratio scales for control performance that are suited to measure disturbance rejection and setpoint tracking, and both their static and dynamic aspects. Conclusion Our concept of buffering provides a powerful mathematical tool for the quantitation of buffering action in all its appearances. PMID:15771784

  16. Action Research in Special Education: An Inquiry Approach for Effective Teaching and Learning. Practitioner Inquiry Series

    ERIC Educational Resources Information Center

    Bruce, Susan M.; Pine, Gerald J.

    2010-01-01

    This is the first book about action research devoted to the complex issues faced by children with disabilities and their teachers. The authors begin by providing the historical and philosophical underpinnings of action research and then present a framework for conducting action research in special education. In addition, they feature four examples…

  17. An integrated approach for prospectively investigating a mode-of-action for rodent liver effects.

    PubMed

    LeBaron, Matthew J; Geter, David R; Rasoulpour, Reza J; Gollapudi, B Bhaskar; Thomas, Johnson; Murray, Jennifer; Kan, H Lynn; Wood, Amanda J; Elcombe, Cliff; Vardy, Audrey; McEwan, Jillian; Terry, Claire; Billington, Richard

    2013-07-15

    Registration of new plant protection products (e.g., herbicide, insecticide, or fungicide) requires comprehensive mammalian toxicity evaluation including carcinogenicity studies in two species. The outcome of the carcinogenicity testing has a significant bearing on the overall human health risk assessment of the substance and, consequently, approved uses for different crops across geographies. In order to understand the relevance of a specific tumor finding to human health, a systematic, transparent, and hypothesis-driven mode of action (MoA) investigation is, appropriately, an expectation by the regulatory agencies. Here, we describe a novel approach of prospectively generating the MoA data by implementing additional end points to the standard guideline toxicity studies with sulfoxaflor, a molecule in development. This proactive MoA approach results in a more robust integration of molecular with apical end points while minimizing animal use. Sulfoxaflor, a molecule targeting sap-feeding insects, induced liver effects (increased liver weight due to hepatocellular hypertrophy) in an initial palatability probe study for selecting doses for subsequent repeat-dose dietary studies. This finding triggered the inclusion of dose-response investigations of the potential key events for rodent liver carcinogenesis, concurrent with the hazard assessment studies. As predicted, sulfoxaflor induced liver tumors in rats and mice in the bioassays. The MoA data available by the time of the carcinogenicity finding supported the conclusion that the carcinogenic potential of sulfoxaflor was due to CAR/PXR nuclear receptor activation with subsequent hepatocellular proliferation. This MoA was not considered to be relevant to humans as sulfoxaflor is unlikely to induce hepatocellular proliferation in humans and therefore would not be a human liver carcinogen.

  18. HELCOM Baltic Sea Action Plan--a regional programme of measures for the marine environment based on the Ecosystem Approach.

    PubMed

    Backer, Hermanni; Leppänen, Juha-Markku; Brusendorff, Anne Christine; Forsius, Kaj; Stankiewicz, Monika; Mehtonen, Jukka; Pyhälä, Minna; Laamanen, Maria; Paulomäki, Hanna; Vlasov, Nikolay; Haaranen, Tarja

    2010-05-01

    The Helsinki Commission (HELCOM) Baltic Sea Action Plan, adopted by the coastal countries of the Baltic Sea and the European Community in November 2007, is a regional intergovernmental programme of measures for the protection and management of the marine environment explicitly based on the Ecosystem Approach. The Action Plan is structured around a set of Ecological Objectives used to define indicators and targets, including effect-based nutrient input ceilings, and to monitor implementation. The Action Plan strongly links Baltic marine environmental concerns to important socio-economic fields such as agriculture and fisheries and promotes cross-sectoral tools including marine spatial planning. Due to complementarities with the European Union (EU) Marine Strategy Framework Directive, the Action Plan is in essence a pilot for this process without neglecting the important role of the Russian Federation - the only Baltic coastal country not a member of the EU.

  19. An integrated approach for prospectively investigating a mode-of-action for rodent liver effects

    SciTech Connect

    LeBaron, Matthew J.; Geter, David R.; Rasoulpour, Reza J.; Gollapudi, B. Bhaskar; Thomas, Johnson; Murray, Jennifer; Kan, H. Lynn; Wood, Amanda J.; Elcombe, Cliff; Vardy, Audrey; McEwan, Jillian; Terry, Claire; Billington, Richard

    2013-07-15

    Registration of new plant protection products (e.g., herbicide, insecticide, or fungicide) requires comprehensive mammalian toxicity evaluation including carcinogenicity studies in two species. The outcome of the carcinogenicity testing has a significant bearing on the overall human health risk assessment of the substance and, consequently, approved uses for different crops across geographies. In order to understand the relevance of a specific tumor finding to human health, a systematic, transparent, and hypothesis-driven mode of action (MoA) investigation is, appropriately, an expectation by the regulatory agencies. Here, we describe a novel approach of prospectively generating the MoA data by implementing additional end points to the standard guideline toxicity studies with sulfoxaflor, a molecule in development. This proactive MoA approach results in a more robust integration of molecular with apical end points while minimizing animal use. Sulfoxaflor, a molecule targeting sap-feeding insects, induced liver effects (increased liver weight due to hepatocellular hypertrophy) in an initial palatability probe study for selecting doses for subsequent repeat-dose dietary studies. This finding triggered the inclusion of dose-response investigations of the potential key events for rodent liver carcinogenesis, concurrent with the hazard assessment studies. As predicted, sulfoxaflor induced liver tumors in rats and mice in the bioassays. The MoA data available by the time of the carcinogenicity finding supported the conclusion that the carcinogenic potential of sulfoxaflor was due to CAR/PXR nuclear receptor activation with subsequent hepatocellular proliferation. This MoA was not considered to be relevant to humans as sulfoxaflor is unlikely to induce hepatocellular proliferation in humans and therefore would not be a human liver carcinogen. - Highlights: • We prospectively generated MoA data into standard guideline toxicity studies. • A proactive MoA approach

  20. A Synthesis and Application Teaching Approach for Group Projects in an Undergraduate Business Course: An Action Research Study

    ERIC Educational Resources Information Center

    Green, Laurena E.

    2009-01-01

    Scholars proposed it would be possible to enhance group effectiveness and functioning if people could develop a better appreciation of the processes surrounding group development (M. K. Smith, 2005). The action research study explored the facilitation of a synthesis and application teaching approach for group projects in the practice of two…

  1. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 489: WWII UXO Sites, Tonopah Test Range, Nevada; May 2005

    SciTech Connect

    Bechtel Nevada; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2005-05-01

    This Streamlined Approach for Environmental Restoration Plan provides the details for the closure of Corrective Action Unit (CAU) 489: WWII UXO Sites, Tonopah Test Range. CAU 489 is located at the Tonopah Test Range and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order of 1996.

  2. STREAMLINED APPROACH FOR ENVIRONMENTAL RESTORATION PLAN FOR CORRECTIVE ACTION UNIT 116: AREA 25 TEST CELL C FACILITYNEVADA TEST SITE, NEVADA

    SciTech Connect

    2006-07-01

    This Streamlined Approach for Environmental Restoration Plan identifies the activities required for the closure of Corrective Action Unit 116, Area 25 Test Cell C Facility. The Test Cell C Facility is located in Area 25 of the Nevada Test Site approximately 25 miles northwest of Mercury, Nevada.

  3. Youth Participatory Action Research as an Approach to Sociopolitical Development and the New Academic Standards: Considerations for Educators

    ERIC Educational Resources Information Center

    Kornbluh, Mariah; Ozer, Emily J.; Allen, Carrie D.; Kirshner, Ben

    2015-01-01

    Administrators and teachers face changes prompted by the shift to Common Core State Standards (CCSS) and Next Generation Science Standards (NGSS). Youth Participatory Action Research (YPAR) offers a promising approach to supporting students in mastering new content standards, while also offering experiences that promote their sociopolitical…

  4. Putting Technological, Pedagogical, and Content Knowledge (TPACK) in Action: An Integrated TPACK-Design-Based Learning (DBL) Approach

    ERIC Educational Resources Information Center

    Baran, Evrim; Uygun, Erdem

    2016-01-01

    Design-based learning (DBL) has been considered a useful approach in teacher education because of its emphasis on the investigation of technology integration problems in design processes. Despite recent interest in understanding how technological, pedagogical, and content knowledge (TPACK) translates to action, limited research exists on how TPACK…

  5. Using a Participatory Action Research Approach to Create a Universally Designed Inclusive High School Science Course: A Case Study

    ERIC Educational Resources Information Center

    Dymond, Stacy K.; Renzaglia, Adelle; Rosenstein, Amy; Chun, Eul Jung; Banks, Ronald A.; Niswander, Vicki; Gilson, Christie L.

    2006-01-01

    Case study methodology was used in combination with a participatory action research (PAR) approach to examine the process of redesigning one high school science course to incorporate the principles of Universal Design for Learning (UDL) and to promote access to the general curriculum. The participants included one general education teacher and two…

  6. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 114: Area 25 EMAD Facility Nevada Test Site, Nevada

    SciTech Connect

    Mark Krauss

    2010-06-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 114, Area 25 EMAD Facility, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 114 comprises the following corrective action site (CAS) located in Area 25 of the Nevada Test Site: • 25-41-03, EMAD Facility This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 25-41-03. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 114 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for CAS 25-41-03. It is anticipated that the results of the field investigation and implementation of corrective actions will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The CAS will be investigated based on the data quality objectives (DQOs) developed on April 30, 2009, by representatives of NDEP and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAS 25-41-03. The following text summarizes the SAFER

  7. Head and Hand: An Action Approach to Thinking. Occasional Paper No. 3.

    ERIC Educational Resources Information Center

    Scribner, Sylvia

    Much research has focused on cognitive skills in isolation from daily life and from action. However, memory and thinking in daily life are not separate from, but are part of, doing. This study is based on a theoretical framework that encompasses an integrated account of mind in action. This "activity theory" holds that neither mind as such nor…

  8. Language, Thinking and Action: Towards a Semio-Constructivist Approach in Physical Education

    ERIC Educational Resources Information Center

    Wallian, Nathalie; Chang, Ching-Wei

    2007-01-01

    Background: Research about sport pedagogy has recently emerged as a significant interest in student reflective practice within the PE teaching/learning system. This learning process is considered as a type of knowledge of co-construction in action. This epistemological assumption postulates that the "knowledge-in-action" is the result of an active…

  9. Testing mixed action approaches to meson spectroscopy with twisted mass sea quarks

    NASA Astrophysics Data System (ADS)

    Berlin, J.; Palao, D.; Wagner, M.

    We explore and compare three mixed action setups with Wilson twisted mass sea quarks and different valence quark actions: (1) Wilson twisted mass, (2) Wilson twisted mass + clover and (3) Wilson + clover. Our main goal is to reduce lattice discretization errors in mesonic spectral quantities, in particular to reduce twisted mass parity and isospin breaking.

  10. Youth Participatory Action Research: A Transformative Approach to Service-Learning

    ERIC Educational Resources Information Center

    Schensul, Jean J.; Berg, Marlene

    2004-01-01

    This article describes a model of participatory action research and service-learning conducted with urban, high school African American, West Indian/Caribbean, and Puerto Rican/Latino youth and adult facilitators, in a nonclassroom setting, in a mid-sized northeastern city. Youth Participatory Action Research (YPAR) integrates critical theory,…

  11. Design of dual action antibiotics as an approach to search for new promising drugs

    NASA Astrophysics Data System (ADS)

    Tevyashova, A. N.; Olsufyeva, E. N.; Preobrazhenskaya, M. N.

    2015-01-01

    The review is devoted to the latest achievements in the design of dual action antibiotics — heterodimeric (chimeric) structures based on antibacterial agents of different classes (fluoroquinolones, anthracyclines, oxazolidines, macrolides and so on). Covalent binding can make the pharmacokinetic characteristics of these molecules more predictable and improve the penetration of each component into the cell. Consequently, not only does the drug efficacy increase owing to inhibition of two targets but also the resistance to one or both antibiotics can be overcome. The theoretical grounds of elaboration, design principles and methods for the synthesis of dual action antibiotics are considered. The structures are classified according to the type of covalent spacer (cleavable or not) connecting the moieties of two agents. Dual action antibiotics with a spacer that can be cleaved in a living cell are considered as dual action prodrugs. Data on the biological action of heterodimeric compounds are presented and structure-activity relationships are analyzed. The bibliography includes 225 references.

  12. Trust, reciprocity and collective action to fight antibiotic resistance. An experimental approach.

    PubMed

    Rönnerstrand, Björn; Andersson Sundell, Karolina

    2015-10-01

    Antibiotic resistance is a collective action dilemma. Individuals may request antibiotics, but an overall reduction in use is necessary to limit resistance. A reoccurring theoretical claim is that social capital increase cooperation in social dilemmas. The aim of this paper is to investigate the link between generalized trust and reciprocity and the willingness to postpone antibiotic treatment in order to limit overuse in a scenario-based study. A between-subject scenario experimental approach with hypothetical scenarios was utilized. Participants were asked to imagine that they were seeing a doctor for a respiratory infection. The doctor prescribes antibiotics, but advise postponing therapy to see if the disease resolves by itself, for the sake of limiting overuse. Respondents were asked to answer how long they could accept postponing antibiotic treatment, from 0 to 7 days. The number of days that most people would be able to accept postponing treatment was considered the between-subject factor. In total, the study sample included 981 respondents with a mean age of 51 years. A majority of respondents were men (65.7%). The mean number of days that the respondents stated they were willing to postpone antibiotic treatment was positively associated with the number of days the respondents were told that most people were willing to postpone antibiotic treatment, p < 0.001. There was a positive association between number of days they were willing to postpone antibiotic treatment and generalized trust, p = 0.001. In conclusion, the results showed that the proclaimed public willingness to postpone therapy influenced a respondent's willingness to postpone antibiotic therapy in different scenarios. Also, generalized trust was positively associated with the willingness to postpone therapy.

  13. [Study on action mechanism of Danhong injection based on computational system biology approach].

    PubMed

    Lv, Yan-ni; Wei, Xiao-hua; Xiao, Pin

    2015-02-01

    Danhong injection is a compound preparation of traditional Chinese medicine Salvia miltiorrhiza and Carthamus tinctorius, and has been widely applied in treating coronary heart diseases and ischemic encephalopathy in clinic. Despite the complexity of its chemical compounds and the diversity of targets, especially in system biology, there have not a report for its action mechanism as a whole regulatory biological network. In this study, protein data of S. miltiorrhiza and C. tinctorius were searched in TCMGeneDIT database and agilent literature search (ALS) system to establish the multi-component protein network of S. miltiorrhiza, C. tinctorius and Danhong injection. Besides, the protein interaction network was built based on the protein-protein interaction in Genecards, BIND, BioGRID, IntAct, MINT and other databases. According to the findings, 10 compounds of S. miltiorrhiza and 14 compounds of C. tinctorius were correlated with proteins. The 24 common compounds had interactions with 81 proteins, and formed a protein interaction network with 60 none-isolated nodes. The Cluster ONE module was applied to make an enrichment analysis on the protein interaction network and extract one sub-network with significant difference P <0.05. The sub-network contains 23 key proteins, which involved five signaling pathways, namely Nod-like receptor signaling pathway, epithelial cell signaling in helicobacter pylori infection, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway and neurotrophin signaling pathway through KEGG signaling pathway mapping. In this study, the computational system biology approach was adopted to preliminarily explain the molecular mechanism of main compounds of Danhong injection in preventing and treating diseases and provide reference for systematic studies on traditional Chinese medicine compounds.

  14. The causal model approach to nutritional problems: an effective tool for research and action at the local level.

    PubMed

    Tonglet, R; Mudosa, M; Badashonderana, M; Beghin, I; Hennart, P

    1992-01-01

    Reported are the results of a case study from Kirotshe rural health district, Northern Kivu, Zaire, where a workshop on the causal model approach to nutrition was organized in 1987. The model has since been used in the field for research design, training of health professionals, nutrition intervention, and community development. The rationale behind this approach is reviewed, the experience accumulated from Kirotshe district is described, and the ways in which the causal model contributes to comprehensive health and nutrition care are discussed. The broad range of possible policy implications of this approach underlines its usefulness for future action.

  15. The causal model approach to nutritional problems: an effective tool for research and action at the local level.

    PubMed Central

    Tonglet, R.; Mudosa, M.; Badashonderana, M.; Beghin, I.; Hennart, P.

    1992-01-01

    Reported are the results of a case study from Kirotshe rural health district, Northern Kivu, Zaire, where a workshop on the causal model approach to nutrition was organized in 1987. The model has since been used in the field for research design, training of health professionals, nutrition intervention, and community development. The rationale behind this approach is reviewed, the experience accumulated from Kirotshe district is described, and the ways in which the causal model contributes to comprehensive health and nutrition care are discussed. The broad range of possible policy implications of this approach underlines its usefulness for future action. PMID:1486667

  16. The SPIRIT Action Framework: A structured approach to selecting and testing strategies to increase the use of research in policy.

    PubMed

    Redman, Sally; Turner, Tari; Davies, Huw; Williamson, Anna; Haynes, Abby; Brennan, Sue; Milat, Andrew; O'Connor, Denise; Blyth, Fiona; Jorm, Louisa; Green, Sally

    2015-07-01

    The recent proliferation of strategies designed to increase the use of research in health policy (knowledge exchange) demands better application of contemporary conceptual understandings of how research shapes policy. Predictive models, or action frameworks, are needed to organise existing knowledge and enable a more systematic approach to the selection and testing of intervention strategies. Useful action frameworks need to meet four criteria: have a clearly articulated purpose; be informed by existing knowledge; provide an organising structure to build new knowledge; and be capable of guiding the development and testing of interventions. This paper describes the development of the SPIRIT Action Framework. A literature search and interviews with policy makers identified modifiable factors likely to influence the use of research in policy. An iterative process was used to combine these factors into a pragmatic tool which meets the four criteria. The SPIRIT Action Framework can guide conceptually-informed practical decisions in the selection and testing of interventions to increase the use of research in policy. The SPIRIT Action Framework hypothesises that a catalyst is required for the use of research, the response to which is determined by the capacity of the organisation to engage with research. Where there is sufficient capacity, a series of research engagement actions might occur that facilitate research use. These hypotheses are being tested in ongoing empirical work.

  17. Examining predictors of physical activity among inactive middle-aged women: an application of the health action process approach.

    PubMed

    Barg, Carolyn J; Latimer, Amy E; Pomery, Elizabeth A; Rivers, Susan E; Rench, Tara A; Prapavessis, Harry; Salovey, Peter

    2012-01-01

    This study tested several relationships predicted by the Health Action Process Approach (HAPA) in a sample of 175 generally healthy, inactive, middle-aged women (40-65 yrs old) over a 12 week period. Participants' physical activity, risk perceptions, outcome expectancies, action self-efficacy and intention were measured at baseline. Planning and maintenance self-efficacy were measured 4 weeks later. Physical activity behaviour was measured 12 weeks after baseline. The HAPA relationships were examined using a structural equation model. The data fit the model well and revealed several significant relationships. Action self-efficacy was the best predictor of intention. Maintenance self-efficacy was the best predictor of planning and behaviour. Contrary to the tenets of HAPA and to past research, planning did not predict behaviour. Overall, HAPA provides a useful framework for identifying determinants of physical activity intentions and behaviour within a group of inactive, middle-aged women.

  18. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 499: Hydrocarbon Spill Site, Tonopah Test Range, Nevada

    SciTech Connect

    T. M. Fitzmaurice

    2001-09-01

    This Streamlined Approach for Environmental Restoration (SAFER) plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 499, Hydrocarbon Spill Site, Tonopah Test Range (TTR). This CAU is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996). CAU 499 is located on the TTR and consists of the following single Corrective Action Site (CAS) (Figure 1): CAS RG-25-001-RD24 - Radar 24 Diesel Spill Site is a diesel fuel release site that is assumed to have been cased by numerous small historical over fillings, spills and leaks from an above-ground storage tank (AST) over a period of 36 years. The tank was located on the north side of Building 24-50 on the TTR approximately 4.0 kilometers (2.5 miles) southwest of the Area 3 Compound at the end of the Avenue 24.

  19. Exploring multiple intelligences theory in the context of science education: An action research approach

    NASA Astrophysics Data System (ADS)

    Goodnough, Karen Catherine

    2000-10-01

    Since the publication of Frames of Mind: The Theory in Practice, multiple intelligences, theory (Gardner, 1983) has been used by practitioners in a variety of ways to make teaching and learning more meaningful. However, little attention has been focused on exploring the potential of the theory for science teaching and learning. Consequently, this research study was designed to: (1) explore Howard Gardner's theory of multiple intelligences (1983) and its merit for making science teaching and learning more meaningful; (2) provide a forum for teachers to engage in critical self-reflection about their theory and practice in science education; (3) study the process of action research in the context of science education; and (4) describe the effectiveness of collaborative action research as a framework for teacher development and curriculum development. The study reports on the experiences of four teachers (two elementary teachers, one junior high teacher, and one high school teacher) and myself, a university researcher-facilitator, as we participated in a collaborative action research project. The action research group held weekly meetings over a five-month period (January--May, 1999). The inquiry was a qualitative case study (Stake, 1994) that aimed to understand the perspectives of those directly involved. This was achieved by using multiple methods to collect data: audiotaped action research meetings, fieldnotes, semi-structured interviews, journal writing, and concept mapping. All data were analysed on an ongoing basis. Many positive outcomes resulted from the study in areas such as curriculum development, teacher development, and student learning in science. Through the process of action research, research participants became more reflective about their practice and thus, enhanced their pedagogical content knowledge (Shulman, 1987) in science. Students became more engaged in learning science, gained a greater understanding of how they learn, and experienced a

  20. Informing Tobacco Cessation Benefit Use Interventions for Unionized Blue-Collar Workers: A Mixed-Methods Reasoned Action Approach.

    PubMed

    Yzer, Marco; Weisman, Susan; Mejia, Nicole; Hennrikus, Deborah; Choi, Kelvin; DeSimone, Susan

    2015-08-01

    Blue-collar workers typically have high rates of tobacco use but low rates of using tobacco cessation resources available through their health benefits. Interventions to motivate blue-collar tobacco users to use effective cessation support are needed. Reasoned action theory is useful in this regard as it can identify the beliefs that shape tobacco cessation benefit use intentions. However, conventional reasoned action research cannot speak to how those beliefs can best be translated into intervention messages. In the present work, we expand the reasoned action approach by adding additional qualitative inquiry to better understand blue-collar smokers' beliefs about cessation benefit use. Across three samples of unionized blue-collar tobacco users, we identified (1) the 35 attitudinal, normative, and control beliefs that represented tobacco users' belief structure about cessation benefit use; (2) instrumental attitude as most important in explaining cessation intention; (3) attitudinal beliefs about treatment options' efficacy, health effects, and monetary implications of using benefits as candidates for message design; (4) multiple interpretations of cessation beliefs (e.g., short and long-term health effects); and (5) clear implications of these interpretations for creative message design. Taken together, the findings demonstrate how a mixed-method reasoned action approach can inform interventions that promote the use of tobacco cessation health benefits.

  1. Using a combined protection motivation theory and health action process approach intervention to promote exercise during pregnancy.

    PubMed

    Gaston, Anca; Prapavessis, Harry

    2014-04-01

    Despite the benefits of exercise during pregnancy, many expectant mothers are inactive. This study examined whether augmenting a protection motivation theory (PMT) intervention with a Health Action Process Approach can enhance exercise behavior change among pregnant women. Sixty inactive pregnant women were randomly assigned to one of three treatment groups: PMT-only, PMT + action-planning, and PMT + action-and-coping-planning. Week-long objective (accelerometer) and subjective (self-report) exercise measures were collected at baseline, and at 1- and 4-weeks post-intervention. Repeated-measures ANOVAs demonstrated that while all participants reported increased exercise from baseline to 1-week post-intervention, participants in both planning groups were significantly more active (p < .001) than those in the PMT-only group by 4-weeks post-intervention (η (2) = .13 and .15 for accelerometer and self-report data, respectively). In conclusion, augmenting a PMT intervention with action or action-and-coping-planning can enhance exercise behavior change in pregnant women.

  2. Integrating public health and allied health education through a core curriculum: an action research approach.

    PubMed

    Fish, Dale R; Tona, Janice; Burton, Harold; Wietig, Paul T; Trevisan, Maurizio; Ohtake, Patricia J

    2011-01-01

    This paper describes the use of an action research model to effect curricular change--specifically, to develop a core curriculum that prepares public health and health professions students to meet emerging needs in today's health care environment. The action research process is based on a series of steps wherein the problem is identified, data are collected and interpreted, action is taken, and action is reflected upon. These steps are then repeated. Consensus building proceeds as participants engage in continual analysis and implementation of changes, followed by more analysis. This process led to the emergence of three core content focus areas: Population, Wellness and Disability; Evidence-Based Practice; and Communication and Professionalism. "Focus Area Working Groups" were established to further delineate each content area. These groups initially developed 62 learning objectives across the three focus areas. Those objectives were subsequently distilled and refined, resulting in 25 "Core Essentials" that now define the core curriculum and serve as content guides rather than prescriptive learning objectives. The action research model proved to be beneficial in helping faculty from diverse health disciplines build consensus as they identified common professional and interprofessional learning needs.

  3. The Approach for Action Recognition Based on the Reconstructed Phase Spaces

    PubMed Central

    Tu, Hong-bin; Xia, Li-min

    2014-01-01

    This paper presents a novel method of human action recognition, which is based on the reconstructed phase space. Firstly, the human body is divided into 15 key points, whose trajectory represents the human body behavior, and the modified particle filter is used to track these key points for self-occlusion. Secondly, we reconstruct the phase spaces for extracting more useful information from human action trajectories. Finally, we apply the semisupervised probability model and Bayes classified method for classification. Experiments are performed on the Weizmann, KTH, UCF sports, and our action dataset to test and evaluate the proposed method. The compare experiment results showed that the proposed method can achieve was more effective than compare methods. PMID:25436224

  4. A Computational Approach to Steady State Correspondence of Regular and Generalized Mass Action Systems.

    PubMed

    Johnston, Matthew D

    2015-06-01

    It has been recently observed that the dynamical properties of mass action systems arising from many models of biochemical reaction networks can be characterized by considering the corresponding properties of a related generalized mass action system. The correspondence process known as network translation in particular has been shown to be useful in characterizing a system's steady states. In this paper, we further develop the theory of network translation with particular focus on a subclass of translations known as improper translations. For these translations, we derive conditions on the network topology of the translated network which are sufficient to guarantee the original and translated systems share the same steady states. We then present a mixed-integer linear programming algorithm capable of determining whether a mass action system can be corresponded to a generalized system through the process of network translation.

  5. Innovative Approaches to Preventing Child Abuse: Volunteers in Action. Prevention Focus Working Paper 015.

    ERIC Educational Resources Information Center

    National Committee for Prevention of Child Abuse, Chicago, IL.

    Collected in this working paper are summary descriptions of 17 innovative community action programs designed to prevent child abuse. These programs were developed by individuals, community groups, hospitals, and/or state chapters of the National Committee for Prevention of Child Abuse, as well as by other groups and organizations. Located in…

  6. Benefits, Barriers, and Cues to Action of Yoga Practice: A Focus Group Approach

    ERIC Educational Resources Information Center

    Atkinson, Nancy L.; Permuth-Levine, Rachel

    2009-01-01

    Objectives: To explore perceived benefits, barriers, and cues to action of yoga practice among adults. Methods: Focus groups were conducted with persons who had never practiced yoga, practitioners of one year or less, and practitioners for more than one year. The Health Belief Model was the theoretical foundation of inquiry. Results: All…

  7. Environmental Asthma Reduction Potential Estimates for Selected Mitigation Actions in Finland Using a Life Table Approach

    PubMed Central

    Rumrich, Isabell Katharina; Hänninen, Otto

    2015-01-01

    Aims: To quantify the reduction potential of asthma in Finland achievable by adjusting exposures to selected environmental factors. Methods: A life table model for the Finnish population for 1986–2040 was developed and Years Lived with Disability caused by asthma and attributable to the following selected exposures were estimated: tobacco smoke (smoking and second hand tobacco smoke), ambient fine particles, indoor dampness and mould, and pets. Results: At baseline (2011) about 25% of the total asthma burden was attributable to the selected exposures. Banning tobacco was the most efficient mitigation action, leading to 6% reduction of the asthma burden. A 50% reduction in exposure to dampness and mould as well as a doubling in exposure to pets lead each to a 2% reduction. Ban of urban small scale wood combustion, chosen as a mitigation action to reduce exposure to fine particles, leads to a reduction of less than 1% of the total asthma burden. Combination of the most efficient mitigation actions reduces the total asthma burden by 10%. A more feasible combination of mitigation actions leads to 6% reduction of the asthma burden. Conclusions: The adjustment of environmental exposures can reduce the asthma burden in Finland by up to 10%. PMID:26067987

  8. A Partnership Approach to Action Learning within a Masters Educational Programme

    ERIC Educational Resources Information Center

    Harrison, Patricia; Edwards, Carys

    2012-01-01

    This account of practice provides a practical example of the use of action learning within a masters educational programme, an MA in Change Management designed and delivered by a collaborative partnership between the Isle of Anglesey County Council (ACC) and Liverpool Business School (LBS), Liverpool John Moores University. The account has been…

  9. Serving the Needs of Challenged Students at a Private Shanghai School: An Action Research Approach

    ERIC Educational Resources Information Center

    Liu, Jerry

    2013-01-01

    This action research started in year 2009 at LIU Shanghai, a private school for children with autism spectrum disorder, to serve the needs of challenged students. The purpose of this qualitative study was to identify the strengths and challenges of the program, plus solicit recommendations from the parents and teachers for making improvements. The…

  10. An Action Research Approach to Supporting Elite Student-Athletes in Higher Education

    ERIC Educational Resources Information Center

    McKenna, Jim; Dunstan-Lewis, Nicky

    2004-01-01

    Support for elite student-athletes was explored within a single English university using Stringer's (1996) Look, Think, Act model of action research. Entry to the ongoing support programme is competitive and participation is voluntary, with sessions delivered every second week after lectures. Based on supporting documentation, interviews, focus…

  11. Functional genomic approaches for understanding the mode of action of Bacillus sp biocontrol strains

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Complete genome sequencing of several Bacillus sp. strains has shed new light on the mode of action of these antagonists of plant pathogens. The use of genomic data mining tools provided the ability to quickly determine the potential of these strains to produce bioactive secondary metabolites. Our B...

  12. Improving Indigenous Completion Rates in Mainstream TAFE: An Action Research Approach

    ERIC Educational Resources Information Center

    Balatti, Jo; Gargano, Lyn; Goldman, Martha; Wood, Gary; Woodlock, Julie

    2004-01-01

    Indigenous engagement with vocational education and training (VET) has improved significantly, but successful Indigenous completion rates are lower nationally when compared to the overall population. This report, based on an action research project, examines intra-institutional factors at four Queensland TAFE (technical and further education)…

  13. Health Inequity in People with Intellectual Disabilities: From Evidence to Action Applying an Appreciative Inquiry Approach

    ERIC Educational Resources Information Center

    Naaldenberg, Jenneken; Banks, Roger; Lennox, Nick; Ouellette-Kunz, Hélène; Meijer, Marijke; Lantman-de Valk, Henny van Schrojenstein

    2015-01-01

    Background: The current understanding of health inequities in people with intellectual disabilities does not readily translate into improvements in health status or health care. To identify opportunities for action, the 2013 IASSIDD health SIRG conference organized ten intensive workshops. Materials and methods: The workshops each addressed…

  14. Affirmative Action in Employment: Recent Court Approaches to a Difficult Concept.

    ERIC Educational Resources Information Center

    Hodges-Aeberhard, Jane

    1999-01-01

    Examines major decisions in the United States, South Africa, and the European Court of Justice related to affirmative action in the workplace. Suggests explanations for differences among the conclusions reached and argues that more rigorous reasoning might enable courts to reach just and realistic decisions. (JOW)

  15. Dialogue--Missing in Action Competence: A Cultural Historical Activity Theory Approach in a Botswana School

    ERIC Educational Resources Information Center

    Silo, Nthalivi

    2013-01-01

    An in-depth case study on children's participation in environmental management activities in a primary school in Botswana was undertaken, drawing on cultural historical activity theory (CHAT) and the action competence model. This research revealed that due to a lack of dialogue between teachers and children, teachers tended to view children's…

  16. Academic Misconduct: A Goals-Plans-Action Approach to Peer Confrontation and Whistle-Blowing

    ERIC Educational Resources Information Center

    Henningsen, Mary Lynn Miller; Valde, Kathleen S.; Denbow, Jessica

    2013-01-01

    Academic misconduct is a serious, pervasive, communication phenomenon on college campuses. In this study, the goals-plans-action model (Dillard, 1990) was used as a theoretical framework to investigate peer confrontation of cheating and whistle-blowing to a course instructor. In an experiment, participants were asked to respond to measures of…

  17. Teaching Students to Analyze Agency Actions via a NEPA Analysis Approach

    ERIC Educational Resources Information Center

    Whitworth, Paul M.

    2008-01-01

    Future recreation professionals need the ability to analyze the effects of proposed management actions and stakeholder concerns to make good decisions, maintain public support, and comply with state and federal laws. Importantly, when federal funds, lands, permits or licenses are involved, federal law requires consideration of environmental and…

  18. "Raising the Point!": An Artistic Approach in Supporting a Community's Call to Action

    ERIC Educational Resources Information Center

    Mendez, Jason

    2013-01-01

    This article discusses the notion of action and personal agency. The author discusses his experiences constructing an arts installation that supported a grassroots effort to revitalize Hunts Point, a community in the South Bronx that is home to 11,000 families, eighteen waste transfer stations, 40% of New York City's sewage, all of the Bronx's…

  19. Promoting Students' Motivation in Learning Physical Science--An Action Research Approach.

    ERIC Educational Resources Information Center

    Tuan, Hsiao-Lin; Chin, Chi-Chin; Tsai, Chih-Chung

    This study reported how four science teachers used action research to promote their students' motivation in learning physical science. Four teachers with one of their 8th grade physical science classes participated in the study. A combination of qualitative and quantitative research design were used in the study, and data collection included…

  20. An Action Science Research Approach to Reducing Student Tardiness at the High School Level

    ERIC Educational Resources Information Center

    Gile, Curtis S.

    2013-01-01

    The purpose of this action research study was to design, implement, analyze, and evaluate a series of interventions to reduce student tardiness at the high school level. Another purpose of the study was to determine the underlying values, beliefs, and behaviors associated with student tardiness from a faculty and staff perspective. The study…

  1. Climate Masters of Nebraska: An Innovative Action-Based Approach for Climate Change Education

    ERIC Educational Resources Information Center

    Pathak, Tapan B.; Bernadt, Tonya; Umphlett, Natalie

    2014-01-01

    Climate Masters of Nebraska is an innovative educational program that strategically trains community volunteers about climate change science and corresponding ways to reduce greenhouse gas emissions in an interactive and action-based teaching environment. As a result of the program, 91% of participants indicated that they made informed changes in…

  2. Streamlined Approach for (SAFER) Plan for Corrective Action Unit 566: E-MAD Compound, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Mark Krauss

    2010-06-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 566, EMAD Compound, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 566 comprises the following corrective action site (CAS) located in Area 25 of the Nevada Test Site: • 25-99-20, EMAD Compound This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 25-99-20. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 566 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action. It is anticipated that the results of the field investigation and implementation of a corrective action of clean closure will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The data quality objective (DQO) strategy for CAU 566 was developed at a meeting on April 30, 2009, by representatives of NDEP and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAU 566. The following text summarizes the SAFER activities that will

  3. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 130: Storage Tanks, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Alfred Wickline

    2008-07-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 130, Storage Tanks, identified in the Federal Facility Agreement and Consent Order (FFACO) (1996, as amended February 2008). Corrective Action Unit 130 consists of the seven following corrective action sites (CASs) located in Areas 1, 7, 10, 20, 22, and 23 of the Nevada Test Site: • 01-02-01, Underground Storage Tank • 07-02-01, Underground Storage Tanks • 10-02-01, Underground Storage Tank • 20-02-03, Underground Storage Tank • 20-99-05, Tar Residue • 22-02-02, Buried UST Piping • 23-02-07, Underground Storage Tank This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 130 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. The results of the field investigation will support a defensible recommendation that no further corrective action is necessary. This will be presented in a Closure Report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval. The sites will be investigated based on the data quality objectives (DQOs) finalized on April 3, 2008, by representatives of NDEP; U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and National Security Technologies, LLC. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for each CAS in CAU 130. The DQO process developed for this CAU

  4. The Challenge of Evaluating the Intensity of Short Actions in Soccer: A New Methodological Approach Using Percentage Acceleration

    PubMed Central

    Sonderegger, Karin; Tschopp, Markus; Taube, Wolfgang

    2016-01-01

    Purpose There are several approaches to quantifying physical load in team sports using positional data. Distances in different speed zones are most commonly used. Recent studies have used acceleration data in addition in order to take short intense actions into account. However, the fact that acceleration decreases with increasing initial running speed is ignored and therefore introduces a bias. The aim of our study was to develop a new methodological approach that removes this bias. For this purpose, percentage acceleration was calculated as the ratio of the maximal acceleration of the action (amax,action) and the maximal voluntary acceleration (amax) that can be achieved for a particular initial running speed (percentage acceleration [%] = amax,action / amax * 100). Methods To define amax, seventy-two highly trained junior male soccer players (17.1 ± 0.6 years) completed maximal sprints from standing and three different constant initial running speeds (vinit; trotting: ~6.0 km·h–1; jogging: ~10.8 km·h–1; running: ~15.0 km·h–1). Results The amax was 6.01 ± 0.55 from a standing start, 4.33 ± 0.40 from trotting, 3.20 ± 0.49 from jogging and 2.29 ± 0.34 m·s–2 from running. The amax correlated significantly with vinit (r = –0.98) and the linear regression equation of highly-trained junior soccer players was: amax = –0.23 * vinit + 5.99. Conclusion Using linear regression analysis, we propose to classify high-intensity actions as accelerations >75% of the amax, corresponding to acceleration values for our population of >4.51 initiated from standing, >3.25 from trotting, >2.40 from jogging, and >1.72 m·s–2 from running. The use of percentage acceleration avoids the bias of underestimating actions with high and overestimating actions with low initial running speed. Furthermore, percentage acceleration allows determining individual intensity thresholds that are specific for one population or one single player. PMID:27846308

  5. Streamlined Approach for Environmental Restoration Work Plan for Corrective Action Unit 461: Joint Test Assembly Sites and Corrective Action Unit 495: Unconfirmed Joint Test Assembly Sites Tonopah Test Range, Nevada

    SciTech Connect

    Jeff Smith

    1998-08-01

    This Streamlined Approach for Environmental Restoration plan addresses the action necessary for the clean closure of Corrective Action Unit 461 (Test Area Joint Test Assembly Sites) and Corrective Action Unit 495 (Unconfirmed Joint Test Assembly Sites). The Corrective Action Units are located at the Tonopah Test Range in south central Nevada. Closure for these sites will be completed by excavating and evaluating the condition of each artillery round (if found); detonating the rounds (if necessary); excavating the impacted soil and debris; collecting verification samples; backfilling the excavations; disposing of the impacted soil and debris at an approved low-level waste repository at the Nevada Test Site

  6. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 574: Neptune, Nevada National Security Site, Nevada

    SciTech Connect

    NSTec Environmental Restoration

    2011-08-31

    This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for closure of Corrective Action Unit (CAU) 574, Neptune. CAU 574 is included in the Federal Facility Agreement and Consent Order (FFACO) (1996 [as amended March 2010]) and consists of the following two Corrective Action Sites (CASs) located in Area 12 of the Nevada National Security Site: (1) CAS 12-23-10, U12c.03 Crater (Neptune); (2) CAS 12-45-01, U12e.05 Crater (Blanca). This plan provides the methodology for the field activities that will be performed to gather the necessary information for closure of the two CASs. There is sufficient information and process knowledge regarding the expected nature and extent of potential contaminants to recommend closure of CAU 574 using the SAFER process. Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, field screening, analytical results, the results of the data quality objective (DQO) process (Section 3.0), and an evaluation of corrective action alternatives (Appendix B), closure in place with administrative controls is the expected closure strategy for CAU 574. Additional information will be obtained by conducting a field investigation to verify and support the expected closure strategy and provide a defensible recommendation that no further corrective action is necessary. This will be presented in a Closure Report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval.

  7. Participatory action research (PAR): an approach for improving black women's health in rural and remote communities.

    PubMed

    Etowa, Josephine B; Bernard, Wanda Thomas; Oyinsan, Bunmi; Clow, Barbara

    2007-10-01

    Women are among the most disadvantaged members of any community, and they tend to be at greatest risk of illness. Black women are particularly vulnerable and more prone than White women to illnesses associated with social and economic deprivation, including heart disease and diabetes. They utilize preventive health services less often, and when they fall ill, the health of their families and communities typically suffers as well. This article discusses the process of doing innovative participatory action research (PAR) in southwest Nova Scotia Black communities. The effort resulted in the generation of a database, community action, and interdisciplinary analysis of the intersecting inequities that compromise the health and health care of African Canadian women, their families, and their communities. This particular research effort serves as a case study for explicating the key tenets of PAR and the barriers to and contradictions in implementing PAR in a community-academic collaborative research project.

  8. Exploring the use of Virtual Field Trips with elementary school teachers: A collaborative action research approach

    NASA Astrophysics Data System (ADS)

    Scott, Jeffrey Lance

    This research examines how elementary school teachers, when supported, use Virtual Field Trips (VFTs) to address the curricula in meaningful ways. I conducted a qualitative study with six teachers, in a collaborative action research context over a six month period. The teachers, five males and one female, all taught either grade five or six and utilized Virtual Field Trips within a variety of curricula areas including science, social studies, music and language arts. In addition, the thesis examines resulting integration of technology into the regular classroom program as a product of the utilization of Virtual Field Trips. The process of collaborative action research was applied as a means of personal and professional growth both for the participants and the researcher/facilitator. By the end of the research study, all participants had learned to integrate Virtual Field Trips into their classroom program, albeit with different levels of success and in different curricula areas. The development of attitudes, skills and knowledge for students and teachers alike was fostered through the participation in Virtual Field Trips. A common concern regarding the utilization of Virtual Field Trips was the time spent locating an appropriate site that met curricula expectations. Participation in the collaborative action research process allowed each teacher to grow professionally, personally and socially. Each participant strongly encouraged the utilization of a long term project with a common area of exploration as a means for positive professional development. Implications and recommendations for future research on the utilization of Virtual Field Trips, as well as the viability of collaborative action research to facilitate teacher development are presented.

  9. Modeling Approach/Strategy for Corrective Action Unit 97, Yucca Flat and Climax Mine , Revision 0

    SciTech Connect

    Janet Willie

    2003-08-01

    The objectives of the UGTA corrective action strategy are to predict the location of the contaminant boundary for each CAU, develop and implement a corrective action, and close each CAU. The process for achieving this strategy includes modeling to define the maximum extent of contaminant transport within a specified time frame. Modeling is a method of forecasting how the hydrogeologic system, including the underground test cavities, will behave over time with the goal of assessing the migration of radionuclides away from the cavities and chimneys. Use of flow and transport models to achieve the objectives of the corrective action strategy is specified in the FFACO. In the Yucca Flat/Climax Mine system, radionuclide migration will be governed by releases from the cavities and chimneys, and transport in alluvial aquifers, fractured and partially fractured volcanic rock aquifers and aquitards, the carbonate aquifers, and in intrusive units. Additional complexity is associated with multiple faults in Yucca Flat and the need to consider reactive transport mechanisms that both reduce and enhance the mobility of radionuclides. A summary of the data and information that form the technical basis for the model is provided in this document.

  10. Clinical practice guideline development manual: A quality-driven approach for translating evidence into action

    PubMed Central

    Rosenfeld, Richard M.; Shiffman, Richard N.

    2010-01-01

    Background Guidelines translate best evidence into best practice. A well-crafted guideline promotes quality by reducing healthcare variations, improving diagnostic accuracy, promoting effective therapy, and discouraging ineffective – or potentially harmful – interventions. Despite a plethora of published guidelines, methodology is often poorly defined and varies greatly within and among organizations. Purpose This manual describes the principles and practices used successfully by the American Academy of Otolaryngology – Head and Neck Surgery to produce quality-driven, evidence-based guidelines using efficient and transparent methodology for action-ready recommendations with multi-disciplinary applicability. The development process, which allows moving from conception to completion in twelve months, emphasizes a logical sequence of key action statements supported by amplifying text, evidence profiles, and recommendation grades that link action to evidence. Conclusions As clinical practice guidelines become more prominent as a key metric of quality healthcare, organizations must develop efficient production strategies that balance rigor and pragmatism. Equally important, clinicians must become savvy in understanding what guidelines are – and are not – and how they are best utilized to improve care. The information in this manual should help clinicians and organizations achieve these goals. PMID:19464525

  11. Effective-action approach to wave propagation in scalar QED plasmas

    NASA Astrophysics Data System (ADS)

    Shi, Yuan; Fisch, Nathaniel J.; Qin, Hong

    2016-07-01

    A relativistic quantum field theory with nontrivial background fields is developed and applied to study waves in plasmas. The effective action of the electromagnetic 4-potential is calculated ab initio from the standard action of scalar QED using path integrals. The resultant effective action is gauge invariant and contains nonlocal interactions, from which gauge bosons acquire masses without breaking the local gauge symmetry. To demonstrate how the general theory can be applied, we give two examples: a cold unmagnetized plasma and a cold uniformly magnetized plasma. Using these two examples, we show that all linear waves well known in classical plasma physics can be recovered from relativistic quantum results when taking the classical limit. In the opposite limit, classical wave dispersion relations are modified substantially. In unmagnetized plasmas, longitudinal waves propagate with nonzero group velocities even when plasmas are cold. In magnetized plasmas, anharmonically spaced Bernstein waves persist even when plasmas are cold. These waves account for cyclotron absorption features observed in spectra of x-ray pulsars. Moreover, cutoff frequencies of the two nondegenerate electromagnetic waves are red-shifted by different amounts. These corrections need to be taken into account in order to correctly interpret diagnostic results in laser plasma experiments.

  12. Integrated approaches to natural resources management in practice: the catalyzing role of National Adaptation Programmes for Action.

    PubMed

    Stucki, Virpi; Smith, Mark

    2011-06-01

    The relationship of forests in water quantity and quality has been debated during the past years. At the same time, focus on climate change has increased interest in ecosystem restoration as a means for adaptation. Climate change might become one of the key drivers pushing integrated approaches for natural resources management into practice. The National Adaptation Programme of Action (NAPA) is an initiative agreed under the UN Framework Convention on Climate Change. An analysis was done to find out how widely ecosystem restoration and integrated approaches have been incorporated into NAPA priority adaptation projects. The data show that that the NAPAs can be seen as potentially important channel for operationalizing various integrated concepts. Key challenge is to implement the NAPA projects. The amount needed to implement the NAPA projects aiming at ecosystem restoration using integrated approaches presents only 0.7% of the money pledged in Copenhagen for climate change adaptation.

  13. Action physics

    NASA Astrophysics Data System (ADS)

    McGinness, Lachlan P.; Savage, C. M.

    2016-09-01

    More than a decade ago, Edwin Taylor issued a "call to action" that presented the case for basing introductory university mechanics teaching around the principle of stationary action [E. F. Taylor, Am. J. Phys. 71, 423-425 (2003)]. We report on our response to that call in the form of an investigation of the teaching and learning of the stationary action formulation of physics in a first-year university course. Our action physics instruction proceeded from the many-paths approach to quantum physics to ray optics, classical mechanics, and relativity. Despite the challenges presented by action physics, students reported it to be accessible, interesting, motivational, and valuable.

  14. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 408: Bomblet Target Area, Tonopah Test Range, Nevada

    SciTech Connect

    NSTec Environmental Management

    2006-10-01

    This Streamlined Approach for Environmental Restoration Plan provides the details for the closure of Corrective Action Unit (CAU) 408, Bomblet Target Area. CAU 408 is located at the Tonopah Test Range and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order of 1996. One Corrective Action Site (CAS) is included in CAU 408: {lg_bullet} CAS TA-55-002-TAB2, Bomblet Target Areas Based on historical documentation, personnel interviews, process knowledge, site visits, aerial photography, multispectral data, preliminary geophysical surveys, and the results of data quality objectives process (Section 3.0), clean closure will be implemented for CAU 408. CAU 408 closure activities will consist of identification and clearance of bomblet target areas, identification and removal of depleted uranium (DU) fragments on South Antelope Lake, and collection of verification samples. Any soil containing contaminants at concentrations above the action levels will be excavated and transported to an appropriate disposal facility. Based on existing information, contaminants of potential concern at CAU 408 include explosives. In addition, at South Antelope Lake, bomblets containing DU were tested. None of these contaminants is expected to be present in the soil at concentrations above the action levels; however, this will be determined by radiological surveys and verification sample results. The corrective action investigation and closure activities have been planned to include data collection and hold points throughout the process. Hold points are designed to allow decision makers to review the existing data and decide which of the available options are most suitable. Hold points include the review of radiological, geophysical, and analytical data and field observations.

  15. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 134: Aboveground Storage Tanks, Nevada Test Site, Nevada

    SciTech Connect

    NSTec Environmental Restoration

    2008-05-31

    This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for the closure of Corrective Action Unit (CAU) 134, Aboveground Storage Tanks. CAU 134 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996; as amended February 2008) and consists of four Corrective Action Sites (CASs) located in Areas 3, 15, and 29 of the Nevada Test Site (NTS) (Figure 1): (1) CAS 03-01-03, Aboveground Storage Tank; (2) CAS 03-01-04, Tank; (3) CAS 15-01-05, Aboveground Storage Tank; and (4) CAS 29-01-01, Hydrocarbon Stain. CAS 03-01-03 consists of a mud tank that is located at the intersection of the 3-07 and the 3-12 Roads in Area 3 of the NTS. The tank and its contents are uncontaminated and will be dispositioned in accordance with applicable federal, state, and local regulations. This CAS will be closed by taking no further action. CAS 03-01-04 consists of a potable water tank that is located at the Core Complex in Area 3 of the NTS. The tank will be closed by taking no further action. CAS 15-01-05 consists of an aboveground storage tank (AST) and associated impacted soil, if any. This CAS is located on a steep slope near the Climax Mine in Area 15 of the NTS. The AST is empty and will be dispositioned in accordance with applicable federal, state, and local regulations. Soil below the AST will be sampled to identify whether it has been impacted by chemicals at concentrations exceeding the action levels. It appears that the tank is not at its original location. Soil will also be sampled at the original tank location, if it can be found. If soil at either location has been impacted at concentrations that exceed the action levels, then the extent of contamination will be identified and a use restriction (UR) will be implemented. The site may be clean closed if contamination is less than one cubic yard in extent and can be readily excavated. If action levels are not exceeded, then no

  16. The mass-action law based algorithm for cost-effective approach for cancer drug discovery and development

    PubMed Central

    Chou, Ting-Chao

    2011-01-01

    The mass-action law based system analysis via mathematical induction and deduction lead to the generalized theory and algorithm that allows computerized simulation of dose-effect dynamics with small size experiments using a small number of data points in vitro, in animals, and in humans. The median-effect equation of the mass-action law deduced from over 300 mechanism specific-equations has been shown to be the unified theory that serves as the common-link for complicated biomedical systems. After using the median-effect principle as the common denominator, its applications are mechanism-independent, drug unit-independent, and dynamic order-independent; and can be used generally for single drug analysis or for multiple drug combinations in constant-ratio or non-constant ratios. Since the “median” is the common link and universal reference point in biological systems, these general enabling lead to computerized quantitative bio-informatics for econo-green bio-research in broad disciplines. Specific applications of the theory, especially relevant to drug discovery, drug combination, and clinical trials, have been cited or illustrated in terms of algorithms, experimental design and computerized simulation for data analysis. Lessons learned from cancer research during the past fifty years provide a valuable opportunity to reflect, and to improve the conventional divergent approach and to introduce a new convergent avenue, based on the mass-action law principle, for the efficient cancer drug discovery and the low-cost drug development. PMID:22016837

  17. Questions raised by a reasoned action approach: comment on Ogden (2003).

    PubMed

    Ajzen, Icek; Fishbein, Martin

    2004-07-01

    In her critique of social cognition or reasoned action models, J. Ogden (see record 2003-05896-016) claimed that such models are not falsifiable and thus cannot be tested, that the postulated relations among model components are true by definition, and that questionnaires used to test the models may create rather than assess cognitions and thus influence later behavior. The authors of this comment challenge all 3 arguments and contend that the findings Ogden regarded as requiring rejection of the models are, in fact, consistent with them, that there is good evidence for the validity of measures used to assess the models' major constructs, and that the effect of completing a questionnaire on cognitions and subsequent behavior is an empirical question.

  18. A facet approach to extending the normative component of the theory of reasoned action.

    PubMed

    Donald, I; Cooper, S R

    2001-12-01

    Using facet theory, this study addresses the weak explanatory power of normative influence in theories of reasoned action or planned behaviour. A broad normative construct is hypothesized as being characterized by two facets--social unit and behavioural modality--each of which is examined in relation to recreational drug use. A questionnaire was developed from the facets and administered to undergraduate students. Data (N = 181) were analysed using Smallest Space Analysis (SSA). The results suggest that the facets provide an adequate description of the normative construct and that personal and social normative beliefs, behavioural norms and behavioural intentions can be distinguished empirically. The results also lend partial support to Ajzen's (1988; Ajzen & Fishbein, 1977) principle of compatibility. Implications for how social influence is operationalized and conceptualized are also discussed.

  19. Cell culture approaches to understanding the actions of steroid hormones on the insect nervous system.

    PubMed

    Levine, R B; Weeks, J C

    1996-01-01

    During metamorphosis of the hawkmoth, Manduca sexta, ecdysteroids regulate the dendritic remodeling and programmed death of identified motoneurons. These changes contribute to the dramatic reorganization of behavior that accompanies metamorphosis. As a step toward elucidating cellular and molecular mechanisms by which ecdysteroids affect neuronal phenotype, we have investigated the responses of Manduca motoneurons to ecdysteroids in vitro. Following dendritic regression at the end of larval life, thoracic leg motoneurons placed in culture respond to ecdysteroids by an increase in branching complexity, similar to events in vivo. Growth cone structure is affected markedly by ecdysteroids. At pupation, a rise in ecdysteroids triggers the segment-specific death of proleg motoneurons: the same segmental pattern of death is observed when motoneurons from different segments are removed from the nervous system and exposed to ecdysteroids in vitro. These studies provide strong evidence that Manduca motoneurons are direct targets of steroid action and set the stage for further studies of the specific mechanisms involved.

  20. Adopting a Blended Learning Approach: Challenges Encountered and Lessons Learned in an Action Research Study

    ERIC Educational Resources Information Center

    Kenney, Jane; Newcombe, Ellen

    2011-01-01

    Adopting a new teaching approach is often a daunting task especially if one is an early adopter in a limited-resource environment. This article describes the challenges encountered and the strategies used in pilot testing a blended instructional method in a large size class within the college of education at a medium-sized university. The main…

  1. Using Student-Centered Cases in the Classroom: An Action Inquiry Approach to Leadership Development

    ERIC Educational Resources Information Center

    Foster, Pacey; Carboni, Inga

    2009-01-01

    This article addresses the concern that business schools are not adequately developing the practical leadership skills that are required in the real world of management. The article begins by discussing the limitations of traditional case methods for teaching behavioral skills. This approach is contrasted with an alternative case method drawn from…

  2. Reflective Reproduction: A Figurative Approach to Reflecting in, on, and about Action

    ERIC Educational Resources Information Center

    McIntosh, Paul

    2008-01-01

    This article explores the use of active imagination and dialogics as constructs that can be applied reflexively to health care education. Drawing on student data, it discusses some of the primary elements of these ideas, and how they may inform reflection, human inquiry, and pedagogical approaches to personal and professional growth and…

  3. Mode of Action (MOA) and Dose-Response Approaches for Nuclear Receptors

    EPA Science Inventory

    Abstract: The presence of sub-threshold doses for non-cancer and (in appropriate cases) cancer has been the dominant paradigm for the practice of risk assessment, but the application of dose-response modeling approaches that include a threshold have been questioned in a 2009 NRC ...

  4. Development and Psychometric Evaluation of a Health Action Process Approach Inventory for Healthful Diet Among Type 2 Diabetes Patients

    PubMed Central

    Rohani, Hosein; Eslami, Ahmad Ali; Ghaderi, Arsalan; bidkhori, Mohammad; Raei, Mehdi

    2016-01-01

    Background: Long-term effects of diabetes could be prevented or delayed by adopting a proper diet. The aim of this study was to adapt and provide a pilot test using health action process approach (HAPA)-based inventory to capable of capturing significant determinants of healthful diet for diabetics. Methods: The inventory was reviewed by eight diabetes patients and verbal feedbacks with regard the comprehension, item relevance, and potential new content were obtained. Then, the inventory items were evaluated by an expert panel. Next exploratory factor analysis (EFA) was conducted to assess the scale constructs. Criterion validity was measured by Pearson correlation. Finally, reliability measures of internal consistency and test-retest analysis were determined. Results: A total of 121 diabetic patients participated in this study. EFA extracted seven factors (risk-perception, action self-efficacy, outcome expectancies, maintenance self-efficacy, action and coping planning, behavioral intention, and recovery self-efficacy) explaining 81.14% of the total variance. There were significant correlations between behavioral intentions and both outcome expectancies (r = 0.55, P < 0.05) and action self-efficacy (r = 0.31, P < 0.004) and small to moderate correlations (rs = 23–40) between behavior and the volitional constructs of the HAPA model. Cronbach's alpha ranging from 0.65 to 0.95 and intraclass correlation coefficients ranging from 0.71 to 0.92 indicated an acceptable internal consistency. Conclusions: Developed scales were valid and reliable for measuring HAPA variables to be used with type 2 diabetes mellitus patients. Further examination with minority persons is warranted. PMID:27195101

  5. Waveform Similarity Analysis: A Simple Template Comparing Approach for Detecting and Quantifying Noisy Evoked Compound Action Potentials.

    PubMed

    Potas, Jason Robert; de Castro, Newton Gonçalves; Maddess, Ted; de Souza, Marcio Nogueira

    2015-01-01

    Experimental electrophysiological assessment of evoked responses from regenerating nerves is challenging due to the typical complex response of events dispersed over various latencies and poor signal-to-noise ratio. Our objective was to automate the detection of compound action potential events and derive their latencies and magnitudes using a simple cross-correlation template comparison approach. For this, we developed an algorithm called Waveform Similarity Analysis. To test the algorithm, challenging signals were generated in vivo by stimulating sural and sciatic nerves, whilst recording evoked potentials at the sciatic nerve and tibialis anterior muscle, respectively, in animals recovering from sciatic nerve transection. Our template for the algorithm was generated based on responses evoked from the intact side. We also simulated noisy signals and examined the output of the Waveform Similarity Analysis algorithm with imperfect templates. Signals were detected and quantified using Waveform Similarity Analysis, which was compared to event detection, latency and magnitude measurements of the same signals performed by a trained observer, a process we called Trained Eye Analysis. The Waveform Similarity Analysis algorithm could successfully detect and quantify simple or complex responses from nerve and muscle compound action potentials of intact or regenerated nerves. Incorrectly specifying the template outperformed Trained Eye Analysis for predicting signal amplitude, but produced consistent latency errors for the simulated signals examined. Compared to the trained eye, Waveform Similarity Analysis is automatic, objective, does not rely on the observer to identify and/or measure peaks, and can detect small clustered events even when signal-to-noise ratio is poor. Waveform Similarity Analysis provides a simple, reliable and convenient approach to quantify latencies and magnitudes of complex waveforms and therefore serves as a useful tool for studying evoked compound

  6. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 121: Storage Tanks and Miscellaneous Sites, Nevada Test Site, Nevada

    SciTech Connect

    NSTec Environmental Restoration

    2007-06-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for the closure of Corrective Action Unit (CAU) 121, Storage Tanks and Miscellaneous Sites. CAU 121 is currently listed in Appendix III of the ''Federal Facility Agreement and Consent Order'' (FFACO, 1996) and consists of three Corrective Action Sites (CASs) located in Area 12 of the Nevada Test Site (NTS): CAS 12-01-01, Aboveground Storage Tank; CAS 12-01-02, Aboveground Storage Tank; and CAS 12-22-26, Drums; 2 AST's. CASs 12-01-01 and 12-01-02 are located to the west of the Area 12 Camp, and CAS 12-22-26 is located near the U-12g Tunnel, also known as G-tunnel, in Area 12 (Figure 1). The aboveground storage tanks (ASTs) present at CASs 12-01-01 and 12-01-02 will be removed and disposed of at an appropriate facility. Soil below the ASTs will be sampled to identify whether it has been impacted with chemicals or radioactivity above action levels. If impacted soil above action levels is present, the soil will be excavated and disposed of at an appropriate facility. The CAS 12-22-26 site is composed of two overlapping areas, one where drums had formerly been stored, and the other where an AST was used to dispense diesel for locomotives used at G-tunnel. This area is located above an underground radioactive materials area (URMA), and within an area that may have elevated background radioactivity because of containment breaches during nuclear tests and associated tunnel reentry operations. CAS 12-22-26 does not include the URMA or the elevated background radioactivity. An AST that had previously been used to store liquid magnesium chloride (MgCl) was properly disposed of several years ago, and releases from this tank are not an environmental concern. The diesel AST will be removed and disposed of at an appropriate facility. Soil at the former drum area and the diesel AST area will be sampled to identify whether it has been impacted by releases, from the drums or the

  7. On the Nature of the Semiotic Structure of the Didactic Action: The Joint Action Theory in Didactics within a Comparative Approach

    ERIC Educational Resources Information Center

    Sensevy, Gérard; Gruson, Brigitte; Forest, Dominique

    2015-01-01

    In this paper, we first sketch the joint action theory paradigm from a general viewpoint in sciences of culture. Then we specify this generic description by focusing on the joint action theory in didactics (JATD). We elaborate on three currently developed elements of the theory: the reticence-expression dialectics; the contract-milieu dialectics,…

  8. Targeted approaches in the treatment of osteoporosis: differential mechanism of action of denosumab and clinical utility.

    PubMed

    Cavalli, Loredana; Brandi, Maria Luisa

    2012-01-01

    Denosumab is a breakthrough biological drug approved by the Food and Drug Administration and European Medicines Agency for the treatment of osteoporosis in 2010. It is a fully human monoclonal antireceptor activator of nuclear factor kappa-B ligand antibody, which inhibits the activity of osteoclasts, resulting in an antiresorptive effect with a significant increase in bone mineral density. The FREEDOM (Fracture Reduction Evaluation of Denosumab in Osteoporosis every 6 Months) trial, comparing denosumab with no treatment in 7868 women with postmenopausal osteoporosis, showed an important reduction of fracture risk at hip, vertebral, and nonvertebral sites in the treated group, while no statistically significant difference in the incidence of adverse events was detected between denosumab and placebo groups. The specific action of denosumab directed against a key regulator of osteoclasts makes it a valuable tool in preventing the occurrence of skeletal events caused by bone destruction in patients with advanced malignancies. The drug was approved for postmenopausal osteoporosis in women at increased risk of fracture and for the treatment of bone loss associated with androgen deprivation therapy in men with prostate cancer.

  9. Effective action approach to cosmological perturbations in dark energy and modified gravity

    SciTech Connect

    Battye, Richard A.; Pearson, Jonathan A. E-mail: jp@jb.man.ac.uk

    2012-07-01

    In light of upcoming observations modelling perturbations in dark energy and modified gravity models has become an important topic of research. We develop an effective action to construct the components of the perturbed dark energy momentum tensor which appears in the perturbed generalized gravitational field equations, δG{sup μν} = 8πGδT{sup μν}+δU{sup μν} for linearized perturbations. Our method does not require knowledge of the Lagrangian density of the dark sector to be provided, only its field content. The method is based on the fact that it is only necessary to specify the perturbed Lagrangian to quadratic order and couples this with the assumption of global statistical isotropy of spatial sections to show that the model can be specified completely in terms of a finite number of background dependent functions. We present our formalism in a coordinate independent fashion and provide explicit formulae for the perturbed conservation equation and the components of δU{sup μ}{sub ν} for two explicit generic examples: (i) the dark sector does not contain extra fields, L = L(g{sub μν}) and (ii) the dark sector contains a scalar field and its first derivative L = L(g{sub μν},φ,∇{sub μ}φ). We discuss how the formalism can be applied to modified gravity models containing derivatives of the metric, curvature tensors, higher derivatives of the scalar fields and vector fields.

  10. An integrated approach to technological risk analysis and protective action decision-making

    SciTech Connect

    Thompson, P.G.; Clevenger, W.F. |; Copenhaver, E.D.; Coomer, C.J.

    1994-04-01

    Chemical warfare agents stored at eight military installations within the continental United States are scheduled to be destroyed through incineration over the next ten years. Extraordinary measures are being taken at all levels of government to ensure the safety of the public during the storage and disposal phases of the project. Key to protection of the public is development of protective action (PA) strategies, which must be determined prior to and implemented immediately following an accidental chemical release. Three sophisticated, interdependent models (that assess atmospheric dispersion of a chemical, traffic evacuation times, and dose reduction attributable to a particular PA) and a structured operational protocol have seen provided to aid planning and management staff in this decision-making process. To equip individuals to utilize both the models and the protocol, a comprehensive instructional program has been developed that examines the risk-impact-response relationship and provides practice in use of the analytical tools. This instructional program may be able to serve as a prototype for use by other communities and chemical locations needing to analyze and plan for response to risks posed by the presence of hazardous substances.

  11. An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol

    PubMed Central

    Malhotra, Ashim; Bath, Sundeep; Elbarbry, Fawzy

    2015-01-01

    Resveratrol is a phenolic phytochemical, with a stilbene backbone, derived from edible plants such as grape and peanut. It is a bioactive molecule with physiological effects on multiple organ systems. Its effects range from the neuroprotective to the nephroprotective, including cardiovascular, neuronal, and antineoplastic responses as a part of its broad spectrum of action. In this review, we examine the effects of resveratrol on the following organ systems: the central nervous system, including neurological pathology such as Parkinson's and Alzheimer's disease; the cardiovascular system, including disorders such as atherosclerosis, ischemia-reperfusion injury, and cardiomyocyte hypertrophy; the kidneys, including primary and secondary nephropathies and nephrolithiasis; multiple forms of cancer; and metabolic syndromes including diabetes. We emphasize commonalities in extracellular matrix protein alterations and intracellular signal transduction system induction following resveratrol treatment. We summarize the known anti-inflammatory, antioxidative, and cytoprotective effects of resveratrol across disparate organ systems. Additionally, we analyze the available literature regarding the pharmacokinetics of resveratrol formulations used in these studies. Finally, we critically examine select clinical trials documenting a lack of effect following resveratrol treatment. PMID:26180596

  12. An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol.

    PubMed

    Malhotra, Ashim; Bath, Sundeep; Elbarbry, Fawzy

    2015-01-01

    Resveratrol is a phenolic phytochemical, with a stilbene backbone, derived from edible plants such as grape and peanut. It is a bioactive molecule with physiological effects on multiple organ systems. Its effects range from the neuroprotective to the nephroprotective, including cardiovascular, neuronal, and antineoplastic responses as a part of its broad spectrum of action. In this review, we examine the effects of resveratrol on the following organ systems: the central nervous system, including neurological pathology such as Parkinson's and Alzheimer's disease; the cardiovascular system, including disorders such as atherosclerosis, ischemia-reperfusion injury, and cardiomyocyte hypertrophy; the kidneys, including primary and secondary nephropathies and nephrolithiasis; multiple forms of cancer; and metabolic syndromes including diabetes. We emphasize commonalities in extracellular matrix protein alterations and intracellular signal transduction system induction following resveratrol treatment. We summarize the known anti-inflammatory, antioxidative, and cytoprotective effects of resveratrol across disparate organ systems. Additionally, we analyze the available literature regarding the pharmacokinetics of resveratrol formulations used in these studies. Finally, we critically examine select clinical trials documenting a lack of effect following resveratrol treatment.

  13. Climate stabilization wedges in action: a systems approach to energy sustainability for Hawaii Island.

    PubMed

    Johnson, Jeremiah; Chertow, Marian

    2009-04-01

    Pacala and Socolow developed a framework to stabilize global greenhouse gas levels for the next fifty years using wedges of constant size representing an increasing use of existing technologies and approaches for energy efficiency, carbon free generation, renewables, and carbon storage. The research presented here applies their approach to Hawaii Island, with modifications to support local scale analysis and employing a "bottom-up" methodology that allows for wedges of various sizes. A discretely bounded spatial unit offers a testing ground for a holistic approach to improving the energy sector with the identification of local options and limitations to the implementation of a comprehensive energy strategy. Nearly 80% of total primary energy demand across all sectors for Hawaii Island is currently met using petroleum-based fuels.The Sustainable Energy Plan scenario included here presents an internally consistent set of recommendations bounded by local constraints in areas such as transportation efficiency, centralized renewable generation (e.g., geothermal, wind), reduction in transmission losses, and improved building efficiency. This scenario shows thatthe demand for primary energy in 2030 could be reduced by 23% through efficiency measures while 46% could be met by renewable generation, resulting in only 31% of the projected demand being met by fossil fuels. In 2030, the annual releases of greenhouse gases would be 3.2 Mt CO2-eq/year under the Baseline scenario, while the Sustainable Energy Plan would reduce this to 1.2 Mt CO2-eq/year--an annual emissions rate 40% below 2006 levels and 10% below 1990 levels. The total for greenhouse gas emissions during the 24-year study period (2007 to 2030) is 59.9 Mt CO2-eq under the Baseline scenario and 32.5 Mt CO2-eq under the Sustainable Energy Plan scenario. Numerous combinations of efficiency and renewable energy options can be employed in a manner that stabilizes the greenhouse gas emissions of Hawaii Island.

  14. Action approach to cosmological perturbations: the second-order metric in matter dominance

    SciTech Connect

    Boubekeur, Lotfi; Creminelli, Paolo; Vernizzi, Filippo; Norena, Jorge

    2008-08-15

    We study nonlinear cosmological perturbations during post-inflationary evolution, using the equivalence between a perfect barotropic fluid and a derivatively coupled scalar field with Lagrangian [-({partial_derivative}{phi}){sup 2}]{sup (1+w)/2w}. Since this Lagrangian is just a special case of k-inflation, this approach is analogous to the one employed in the study of non-Gaussianities from inflation. We use this method to derive the second-order metric during matter dominance in the comoving gauge directly as a function of the primordial inflationary perturbation {zeta}. Going to Poisson gauge, we recover the metric previously derived in the literature.

  15. Wildlife connectivity approaches and best practices in U.S. state wildlife action plans.

    PubMed

    Lacher, Iara; Wilkerson, Marit L

    2014-02-01

    As habitat loss and fragmentation threaten biodiversity on large geographic scales, creating and maintaining connectivity of wildlife populations is an increasingly common conservation objective. To assess the progress and success of large-scale connectivity planning, conservation researchers need a set of plans that cover large geographic areas and can be analyzed as a single data set. The state wildlife action plans (SWAPs) fulfill these requirements. We examined 50 SWAPs to determine the extent to which wildlife connectivity planning, via linkages, is emphasized nationally. We defined linkage as connective land that enables wildlife movement. For our content analysis, we identified and quantified 6 keywords and 7 content criteria that ranged in specificity and were related to linkages for wide-ranging terrestrial vertebrates and examined relations between content criteria and statewide data on focal wide-ranging species, spending, revenue, and conserved land. Our results reflect nationwide disparities in linkage conservation priorities and highlight the continued need for wildlife linkage planning. Only 30% or less of the 50 SWAPs fulfilled highly specific content criteria (e.g., identifying geographic areas for linkage placement or management). We found positive correlations between our content criteria and statewide data on percent conserved land, total focal species, and spending on parks and recreation. We supplemented our content analysis with interviews with 17 conservation professionals to gain specific information about state-specific context and future directions of linkage conservation. Based on our results, relevant literature, and interview responses, we suggest the following best practices for wildlife linkage conservation plans: collect ecologically meaningful background data; be specific; establish community-wide partnerships; and incorporate sociopolitical and socioeconomic information.

  16. Wildlife connectivity approaches and best practices in U.S. state wildlife action plans

    USGS Publications Warehouse

    Lacher, Iara; Wilkerson, Marit L.

    2014-01-01

    As habitat loss and fragmentation threaten biodiversity on large geographic scales, creating and maintaining connectivity of wildlife populations is an increasingly common conservation objective. To assess the progress and success of large-scale connectivity planning, conservation researchers need a set of plans that cover large geographic areas and can be analyzed as a single data set. The state wildlife action plans (SWAPs) fulfill these requirements. We examined 50 SWAPs to determine the extent to which wildlife connectivity planning, via linkages, is emphasized nationally. We defined linkage as connective land that enables wildlife movement. For our content analysis, we identified and quantified 6 keywords and 7 content criteria that ranged in specificity and were related to linkages for wide-ranging terrestrial vertebrates and examined relations between content criteria and statewide data on focal wide-ranging species, spending, revenue, and conserved land. Our results reflect nationwide disparities in linkage conservation priorities and highlight the continued need for wildlife linkage planning. Only 30% or less of the 50 SWAPs fulfilled highly specific content criteria (e.g., identifying geographic areas for linkage placement or management). We found positive correlations between our content criteria and statewide data on percent conserved land, total focal species, and spending on parks and recreation. We supplemented our content analysis with interviews with 17 conservation professionals to gain specific information about state-specific context and future directions of linkage conservation. Based on our results, relevant literature, and interview responses, we suggest the following best practices for wildlife linkage conservation plans: collect ecologically meaningful background data; be specific; establish community-wide partnerships; and incorporate sociopolitical and socioeconomic information.

  17. Moving from conceptual ambiguity to knowledgeable action: using a critical realist approach to studying moral distress.

    PubMed

    Musto, Lynn C; Rodney, Patricia A

    2016-04-01

    Moral distress is a phenomenon that has been receiving increasing attention in nursing and other health care disciplines. Moral distress is a concept that entered the nursing literature - and subsequently the health care ethics lexicon - in 1984 as a result of the work done by American philosopher and bioethicist Andrew Jameton. Over the past decade, research into moral distress has extended beyond the profession of nursing as other health care disciplines have come to question the impact of moral constraint on individual practitioners, professional practice, and patient outcomes. Along with increased interest in the phenomenon of moral distress have come increasing critiques - critiques that in their essence point to a serious lack of conceptual clarity in the definition, study, and application of the concept. Foundational to gaining conceptual clarity in moral distress in order to develop strategies to prevent and ameliorate the experience is a careful revisiting of the epistemological assumptions underpinning our knowledge and use of the concept of moral distress. It is our contention that the conceptual challenges reveal flaws in the original understanding of moral distress that are based on an epistemological stance that holds a linear conception of cause and effect coupled with a simplistic perspective of 'constraint' and 'agency'. We need a more nuanced approach to our study of moral distress such that our ontological and epistemological stances help us to better appreciate the complexity of moral agents acting in organizational contexts. We believe that critical realism offers such a nuanced approach.

  18. Tools for thoughtful action: the role of ecosystem approaches to health in enhancing public health.

    PubMed

    Webb, Jena C; Mergler, Donna; Parkes, Margot W; Saint-Charles, Johanne; Spiegel, Jerry; Waltner-Toews, David; Yassi, Annalee; Woollard, Robert F

    2010-01-01

    The intimate interdependence of human health and the ecosystems in which we are embedded is now a commonplace observation. For much of the history of public health, this was not so obvious. After over a century of focus on diseases, their biologic causes and the correction of exposures (clean water and air) and facilitation of responses (immunizations and nutrition), public health discourse shifted to embrace the concept of determinants of health as extending to social, economic and environmental realms. This moved the discourse and science of public health into an unprecedented level of complexity just as public concern about the environment heightened. To address multifactorial, dynamic impacts on health, a new paradigm was needed which would overcome the separation of humans and ecosystems. Ecosystem approaches to health arose in the 1990s from a rich background of intellectual ferment as Canada wrestled with diverse problems ranging from Great Lakes contamination to zoonotic diseases. Canada's International Development Research Centre (IDRC) played a lead role in supporting an international community of scientists and scholars who advanced ecosystem approaches to health. These collective efforts have enabled a shift to a research paradigm that embraces transdisciplinarity, social justice, gender equity, multi-stakeholder participation and sustainability.

  19. An fMRI approach to particularize the frontoparietal network for visuomotor action monitoring: Detection of incongruence between test subjects' actions and resulting perceptions.

    PubMed

    Schnell, Knut; Heekeren, Karsten; Schnitker, Ralf; Daumann, Jörg; Weber, Jochen; Hesselmann, Volker; Möller-Hartmann, Walter; Thron, Armin; Gouzoulis-Mayfrank, Euphrosyne

    2007-01-01

    Contemporary theories of motor control assume that motor actions underlie a supervisory control system which utilizes reafferent sensory feedbacks of actions for comparison with the original motor programs. The functional network of visuomotor action monitoring is considered to include inferior parietal, lateral and medial prefrontal cortices. To study both sustained monitoring for visuomotor incongruence and the actual detection of incongruence, we used a hybrid fMRI epoch-/event-related design. The basic experimental task was a continuous motor task, comprising a simple racing game. Within certain blocks of this task, incongruence was artificially generated by intermittent takeover of control over the car by the computer. Fifteen male subjects were instructed to monitor for incongruence between their own and the observed actions in order to abstain from their own action whenever the computer took over control. As a result of both sustained monitoring and actual detection of visuomotor incongruence, the rostral inferior parietal lobule displayed a BOLD signal increase. In contrast, the prefrontal cortex (PFC) exhibited two different activation patterns. Dorsolateral (BA 9/46) and medial/cingulate (BA 8, BA 32) areas of the PFC displayed a greater increase of activation in sustained monitoring, while ventrolateral PFC showed greater event-related activation for the actual detection of visuomotor incongruence. Our results suggest that the rostral inferior parietal lobule is specifically involved in the reafferent comparison of the test subjects' own actions and visually perceived actions. Different activation patterns of the PFC may reflect different frontoparietal networks for sustained action monitoring and actual detection of reafferent incongruence.

  20. A Systems Biology Approach to Understanding the Mechanisms of Action of Chinese Herbs for Treatment of Cardiovascular Disease

    PubMed Central

    Li, Bohui; Xu, Xue; Wang, Xia; Yu, Hua; Li, Xiuxiu; Tao, Weiyang; Wang, Yonghua; Yang, Ling

    2012-01-01

    Traditional Chinese Medicine (TCM) involves a broad range of empirical testing and refinement and plays an important role in the health maintenance for people all over the world. However, due to the complexity of Chinese herbs, a full understanding of TCM’s action mechanisms is still unavailable despite plenty of successful applications of TCM in the treatment of various diseases, including especially cardiovascular diseases (CVD), one of the leading causes of death. Thus in the present work, by incorporating the chemical predictors, target predictors and network construction approaches, an integrated system of TCM has been constructed to systematically uncover the underlying action mechanisms of TCM. From three representative Chinese herbs, i.e., Ligusticum chuanxiong Hort., Dalbergia odorifera T. Chen and Corydalis yanhusuo WT Wang which have been widely used in CVD treatment, by combinational use of drug absorption, distribution, metabolism and excretion (ADME) screening and network pharmacology techniques, we have generated 64 bioactive ingredients and identified 54 protein targets closely associated with CVD, of which 29 are common targets (52.7%) of the three herbs. The result provides new information on the efficiency of the Chinese herbs for the treatment of CVD and also explains one of the basic theories of TCM, i.e., “multiple herbal drugs can treat one disease”. The predicted potential targets were then mapped to target-disease and target-signal pathway connections, which revealed the relationships of the active ingredients with their potential targets, diseases and signal systems. This means that for the first time, the action mechanism of these three important Chinese herbs for the treatment of CVD is uncovered, by generating and identifying both their active ingredients and novel targets specifically related to CVD, which clarifies some of the common conceptions in TCM, and thus provides clues to modernize such specific herbal medicines. PMID

  1. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 107: Low Impact Soil Sites, Nevada Test Site, Nevada

    SciTech Connect

    NSTec Environmental Restoration

    2009-03-31

    This Streamlined Approach for Environmental Restoration Plan covers activities associated with Corrective Action Unit (CAU) 107 of the Federal Facility Agreement and Consent Order (1996 [as amended February 2008]). CAU 107 consists of the following Corrective Action Sites (CASs) located in Areas 1, 2, 3, 4, 5, 9, 10, and 18 of the Nevada Test Site. {sm_bullet} CAS 01-23-02, Atmospheric Test Site - High Alt{sm_bullet} CAS 02-23-02, Contaminated Areas (2){sm_bullet} CAS 02-23-03, Contaminated Berm{sm_bullet} CAS 02-23-10, Gourd-Amber Contamination Area{sm_bullet} CAS 02-23-11, Sappho Contamination Area{sm_bullet} CAS 02-23-12, Scuttle Contamination Area{sm_bullet} CAS 03-23-24, Seaweed B Contamination Area{sm_bullet} CAS 03-23-27, Adze Contamination Area{sm_bullet} CAS 03-23-28, Manzanas Contamination Area{sm_bullet} CAS 03-23-29, Truchas-Chamisal Contamination Area{sm_bullet} CAS 04-23-02, Atmospheric Test Site T4-a{sm_bullet} CAS 05-23-06, Atmospheric Test Site{sm_bullet} CAS 09-23-06, Mound of Contaminated Soil{sm_bullet} CAS 10-23-04, Atmospheric Test Site M-10{sm_bullet} CAS 18-23-02, U-18d Crater (Sulky) Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, engineering drawings, field screening, analytical results, and the results of data quality objectives process (Section 3.0), closure in place with administrative controls or no further action will be implemented for CAU 107.

  2. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 107: Low Impact Soil Sites, Nevada Test Site, Nevada

    SciTech Connect

    NSTec Environmental Restoration

    2008-09-30

    This Streamlined Approach for Environmental Restoration Plan covers activities associated with Corrective Action Unit (CAU) 107 of the Federal Facility Agreement and Consent Order (FFACO, 1996 [as amended February 2008]). CAU 107 consists of the following Corrective Action Sites (CASs) located in Areas 1, 2, 3, 4, 5, 9, 10, and 18 of the Nevada Test Site. (1) CAS 01-23-02, Atmospheric Test Site - High Alt; (2) CAS 02-23-02, Contaminated Areas (2); (3) CAS 02-23-03, Contaminated Berm; (4) CAS 02-23-10, Gourd-Amber Contamination Area; (5) CAS 02-23-11, Sappho Contamination Area; (6) CAS 02-23-12, Scuttle Contamination Area; (7) CAS 03-23-24, Seaweed B Contamination Area; (8) CAS 03-23-27, Adze Contamination Area; (9) CAS 03-23-28, Manzanas Contamination Area; (10) CAS 03-23-29, Truchas-Chamisal Contamination Area; (11) CAS 04-23-02, Atmospheric Test Site T4-a; (12) CAS 05-23-06, Atmospheric Test Site; (13) CAS 09-23-06, Mound of Contaminated Soil; (14) CAS 10-23-04, Atmospheric Test Site M-10; and (15) CAS 18-23-02, U-18d Crater (Sulky). Based on historical documentation, personnel interviews, site process knowledge, site visits, photographs, engineering drawings, field screening, analytical results, and the results of data quality objectives process (Section 3.0), closure in place with administrative controls or no further action will be implemented for CAU 107. CAU 107 closure activities will consist of verifying that the current postings required under Title 10 Code of Federal Regulations (CFR) Part 835 are in place and implementing use restrictions (URs) at two sites, CAS 03-23-29 and CAS 18-23-02. The current radiological postings combined with the URs are adequate administrative controls to limit site access and worker dose.

  3. Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine

    PubMed Central

    Hsieh, Yao-Yu; Huang, Tsui-Chin; Lo, Hsiang-Ling; Jhan, Jyun-Yan; Chen, Shui-Tein; Yang, Pei-Ming

    2016-01-01

    Polypharmacology (the ability of a drug to affect more than one molecular target) is considered a basic property of many therapeutic small molecules. Herein, we used a chemical genomics approach to systematically analyze polypharmacology by integrating several analytical tools, including the LINCS (Library of Integrated Cellular Signatures), STITCH (Search Tool for Interactions of Chemicals), and WebGestalt (WEB-based GEne SeT AnaLysis Toolkit). We applied this approach to identify functional disparities between two cytidine nucleoside analogs: azacytidine (AZA) and decitabine (DAC). AZA and DAC are structurally and mechanistically similar DNA-hypomethylating agents. However, their metabolism and destinations in cells are distinct. Due to their differential incorporation into RNA or DNA, functional disparities between AZA and DAC are expected. Indeed, different cytotoxicities of AZA and DAC toward human colorectal cancer cell lines were observed, in which cells were more sensitive to AZA. Based on a polypharmacological analysis, we found that AZA transiently blocked protein synthesis and induced an acute apoptotic response that was antagonized by concurrently induced cytoprotective autophagy. In contrast, DAC caused cell cycle arrest at the G2/M phase associated with p53 induction. Therefore, our study discriminated functional disparities between AZA and DAC, and also demonstrated the value of this chemical genomics approach that can be applied to discover novel drug action mechanisms. PMID:27036028

  4. The Study of the Development of Writing Skill in the Textbooks of the Action-Oriented Approach, a Case of Iranian Learners of FFL

    ERIC Educational Resources Information Center

    Moradian, Motahareh; Rahmatian, Rouholah

    2016-01-01

    This paper analyses the written competence and corpus of Iranian learners of French at two levels (A1 and A2). The data were collected in a quantified and qualified manner with auto evaluation grids and narrative text writing to analyze the action-oriented approach textbooks' efficiency in writing. Basically the approach of the three manuals,…

  5. Enzymatic mechanochemistry: a new approach to studying the mechanism of enzyme action.

    PubMed

    Klibanov, A M; Samokhin, G P; Martinek, K; Berezin, I V

    1976-06-07

    1. Covalent binding of model enzymes, chymotrypsin and trypsin, to elastic polymer supports, nylon and viscose (cellulose) fibers, human hair, methacrylate rubber, has been effectuated. On mechanical stretching of the fibers, the catalytic activity of the enzymes bound to them decreases, and when they relax, it increases to the initial level. The data obtained by us fit the concept that the effect is due to reversible deformation of the bound enzyme molecules induced by fiber stretching. 2. Analysis of the dependence of the catalytic activity of the enzymes chemically bound to the fiber on the degree of fiber deformation shows that the reversible inactivation of the enzymes induced by support stretching occurs even if the deformation of the enzymes' molecules is as small as 0.5 A. 3. The deformation of the enzyme molecules induced by fiber stretching entails a change in the substrate specificity of the biocatalysts, i.e. the activity towards "good" substrates decreases, and towards "poor" substrates increases. 4. The deformation of the enzyme molecules induced by fiber stretching results in a decrease of the specific catalytic activity of the biocatalyst, whereas its thermal stability increases. 5. The results obtained allowed a new, mechanochemical, approach to be suggested for studying major problems of enzymatic catalysis.

  6. A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum

    PubMed Central

    Castilho-Martins, Emerson A.; Tavares, Marina F. M.; Barbas, Coral; López-Gonzálvez, Ángeles; Rivas, Luis

    2015-01-01

    There is a rising resistance against antimony drugs, the gold-standard for treatment until some years ago. That is a serious problem due to the paucity of drugs in current clinical use. In a research to reveal how these drugs affect the parasite during treatment and to unravel the underlying basis for their resistance, we have employed metabolomics to study treatment in Leishmania infantum promastigotes. This was accomplished first through the untargeted analysis of metabolic snapshots of treated and untreated parasites both resistant and responders, utilizing a multiplatform approach to give the widest as possible coverage of the metabolome, and additionally through novel monitoring of the origin of the detected alterations through a 13C traceability experiment. Our data stress a multi-target metabolic alteration with treatment, affecting in particular the cell redox system that is essential to cope with detoxification and biosynthetic processes. Additionally, relevant changes were noted in amino acid metabolism. Our results are in agreement with other authors studying other Leishmania species. PMID:26161866

  7. A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum.

    PubMed

    Rojo, David; Canuto, Gisele A B; Castilho-Martins, Emerson A; Tavares, Marina F M; Barbas, Coral; López-Gonzálvez, Ángeles; Rivas, Luis

    2015-01-01

    There is a rising resistance against antimony drugs, the gold-standard for treatment until some years ago. That is a serious problem due to the paucity of drugs in current clinical use. In a research to reveal how these drugs affect the parasite during treatment and to unravel the underlying basis for their resistance, we have employed metabolomics to study treatment in Leishmania infantum promastigotes. This was accomplished first through the untargeted analysis of metabolic snapshots of treated and untreated parasites both resistant and responders, utilizing a multiplatform approach to give the widest as possible coverage of the metabolome, and additionally through novel monitoring of the origin of the detected alterations through a 13C traceability experiment. Our data stress a multi-target metabolic alteration with treatment, affecting in particular the cell redox system that is essential to cope with detoxification and biosynthetic processes. Additionally, relevant changes were noted in amino acid metabolism. Our results are in agreement with other authors studying other Leishmania species.

  8. A Machine Learning Approach to Discover Rules for Expressive Performance Actions in Jazz Guitar Music

    PubMed Central

    Giraldo, Sergio I.; Ramirez, Rafael

    2016-01-01

    Expert musicians introduce expression in their performances by manipulating sound properties such as timing, energy, pitch, and timbre. Here, we present a data driven computational approach to induce expressive performance rule models for note duration, onset, energy, and ornamentation transformations in jazz guitar music. We extract high-level features from a set of 16 commercial audio recordings (and corresponding music scores) of jazz guitarist Grant Green in order to characterize the expression in the pieces. We apply machine learning techniques to the resulting features to learn expressive performance rule models. We (1) quantitatively evaluate the accuracy of the induced models, (2) analyse the relative importance of the considered musical features, (3) discuss some of the learnt expressive performance rules in the context of previous work, and (4) assess their generailty. The accuracies of the induced predictive models is significantly above base-line levels indicating that the audio performances and the musical features extracted contain sufficient information to automatically learn informative expressive performance patterns. Feature analysis shows that the most important musical features for predicting expressive transformations are note duration, pitch, metrical strength, phrase position, Narmour structure, and tempo and key of the piece. Similarities and differences between the induced expressive rules and the rules reported in the literature were found. Differences may be due to the fact that most previously studied performance data has consisted of classical music recordings. Finally, the rules' performer specificity/generality is assessed by applying the induced rules to performances of the same pieces performed by two other professional jazz guitar players. Results show a consistency in the ornamentation patterns between Grant Green and the other two musicians, which may be interpreted as a good indicator for generality of the ornamentation rules

  9. A Machine Learning Approach to Discover Rules for Expressive Performance Actions in Jazz Guitar Music.

    PubMed

    Giraldo, Sergio I; Ramirez, Rafael

    2016-01-01

    Expert musicians introduce expression in their performances by manipulating sound properties such as timing, energy, pitch, and timbre. Here, we present a data driven computational approach to induce expressive performance rule models for note duration, onset, energy, and ornamentation transformations in jazz guitar music. We extract high-level features from a set of 16 commercial audio recordings (and corresponding music scores) of jazz guitarist Grant Green in order to characterize the expression in the pieces. We apply machine learning techniques to the resulting features to learn expressive performance rule models. We (1) quantitatively evaluate the accuracy of the induced models, (2) analyse the relative importance of the considered musical features, (3) discuss some of the learnt expressive performance rules in the context of previous work, and (4) assess their generailty. The accuracies of the induced predictive models is significantly above base-line levels indicating that the audio performances and the musical features extracted contain sufficient information to automatically learn informative expressive performance patterns. Feature analysis shows that the most important musical features for predicting expressive transformations are note duration, pitch, metrical strength, phrase position, Narmour structure, and tempo and key of the piece. Similarities and differences between the induced expressive rules and the rules reported in the literature were found. Differences may be due to the fact that most previously studied performance data has consisted of classical music recordings. Finally, the rules' performer specificity/generality is assessed by applying the induced rules to performances of the same pieces performed by two other professional jazz guitar players. Results show a consistency in the ornamentation patterns between Grant Green and the other two musicians, which may be interpreted as a good indicator for generality of the ornamentation rules.

  10. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 538: Spill Sites, Nevada Test Site, Nevada, Rev. No.: 0

    SciTech Connect

    Alfred Wickline

    2006-04-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the closure of Corrective Action Unit (CAU) 538: Spill Sites, Nevada Test Site, Nevada. It has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. A SAFER may be performed when the following criteria are met: (1) Conceptual corrective actions are clearly identified (although some degree of investigation may be necessary to select a specific corrective action before completion of the Corrective Action Investigation [CAI]). (2) Uncertainty of the nature, extent, and corrective action must be limited to an acceptable level of risk. (3) The SAFER Plan includes decision points and criteria for making data quality objective (DQO) decisions. The purpose of the investigation will be to document and verify the adequacy of existing information; to affirm the decision for either clean closure, closure in place, or no further action; and to provide sufficient data to implement the corrective action. The actual corrective action selected will be based on characterization activities implemented under this SAFER Plan. This SAFER Plan identifies decision points developed in cooperation with the Nevada Division of Environmental Protection (NDEP) and where DOE will reach consensus with NDEP before beginning the next phase of work.

  11. Facilitating progress in health behaviour theory development and modification: the reasoned action approach as a case study.

    PubMed

    Head, Katharine J; Noar, Seth M

    2014-01-01

    This paper explores the question: what are barriers to health behaviour theory development and modification, and what potential solutions can be proposed? Using the reasoned action approach (RAA) as a case study, four areas of theory development were examined: (1) the theoretical domain of a theory; (2) tension between generalisability and utility, (3) criteria for adding/removing variables in a theory, and (4) organisational tracking of theoretical developments and formal changes to theory. Based on a discussion of these four issues, recommendations for theory development are presented, including: (1) the theoretical domain for theories such as RAA should be clarified; (2) when there is tension between generalisability and utility, utility should be given preference given the applied nature of the health behaviour field; (3) variables should be formally removed/amended/added to a theory based on their performance across multiple studies and (4) organisations and researchers with a stake in particular health areas may be best suited for tracking the literature on behaviour-specific theories and making refinements to theory, based on a consensus approach. Overall, enhancing research in this area can provide important insights for more accurately understanding health behaviours and thus producing work that leads to more effective health behaviour change interventions.

  12. A multi-scale approach to cost/benefit analyses of landslide prevention vs. post-event actions

    NASA Astrophysics Data System (ADS)

    Salbego, G.; Floris, M.; Busnardo, E.; Toaldo, M.

    2015-02-01

    The main aim of this paper is to test economic benefits of landslide prevention measures vs. post-event emergency actions. To this end, small and large scale analyses were performed in a training area located in the North-Eastern Italian pre-Alps that was hit by an exceptional rainfall event occurred in November 2010. At the small-scale, landslide susceptibility was initially assessed using a simple probabilistic analysis, which allowed to highlight the main landslide conditioning factors and the most hazardous areas. However, this approach revealed to be quite insufficient to reach planned goals, so a large-scale case-by-case analysis was performed: a study case was defined, according to landslide occurrence frequency and assessment of elements at risk. Numerical modeling demonstrated that remedial works carried out after the landslide - water-removal intervention such as a drainage trench - could have improved slope stability if applied before its occurrence. Then, a cost-benefit analysis was finally employed. It defined that prevention would have been economically convenient compared to a non-preventive and passive attitude, allowing a 30% saving relative to total costs. Therefore, this kind of approach could be actually used as a mean toward preventive soil protection not only within the investigated case study, but also in all those hazardous areas where preventive measures are needed.

  13. Dose-response approaches for nuclear receptor-mediated modes of action for liver carcinogenicity: Results of a workshop.

    PubMed

    Andersen, Melvin E; Preston, R Julian; Maier, Andrew; Willis, Alison M; Patterson, Jacqueline

    2014-01-01

    A public workshop, organized by a Steering Committee of scientists from government, industry, universities and research organizations, was held at the National Institute of Environmental Health Sciences (NIEHS) in September, 2010. The workshop explored the dose-response implications of toxicant modes of action (MOA) mediated by nuclear receptors. The dominant paradigm in human health risk assessment has been linear extrapolation without a threshold for cancer, and estimation of sub-threshold doses for non-cancer and (in appropriate cases) cancer endpoints. However, recent publications question the application of dose-response modeling approaches with a threshold. The growing body of molecular toxicology information and computational toxicology tools has allowed for exploration of the presence or absence of sub-threshold doses for a number of receptor-mediated MOAs. The workshop explored the development of dose-response approaches for nuclear receptor-mediated liver cancer, within a MOA Human Relevance Framework (HRF). Case studies addressed activation of the AHR, the CAR and the PPARα. This article describes the workshop process, key issues discussed and conclusions. The value of an interactive workshop approach to apply current MOA/HRF frameworks was demonstrated. The results may help direct research on the MOA and dose-response of receptor-based toxicity, since there are commonalities for many receptors in the basic pathways involved for late steps in the MOA, and similar data gaps in early steps. Three additional papers in this series describe the results and conclusions for each case-study receptor regarding its MOA, relevance of the MOA to humans and the resulting dose-response implications.

  14. Procuring a Sustainable Future: An Action Learning Approach to the Development and Modelling of Ethical and Sustainable Procurement Practices

    ERIC Educational Resources Information Center

    Boak, George; Watt, Peter; Gold, Jeff; Devins, David; Garvey, Robert

    2016-01-01

    This paper contributes to an understanding of the processes by which organisational actors learn how to affect positive and sustainable social change in their local region through action learning, action research and appreciative inquiry. The paper is based on a critically reflective account of key findings from an ongoing action research project,…

  15. Using a distribution and conservation status weighted hotspot approach to identify areas in need of conservation action to benefit Idaho bird species

    USGS Publications Warehouse

    Haines, Aaron M.; Leu, Matthias; Svancara, Leona K.; Wilson, Gina; Scott, J. Michael

    2010-01-01

    Identification of biodiversity hotspots (hereafter, hotspots) has become a common strategy to delineate important areas for wildlife conservation. However, the use of hotspots has not often incorporated important habitat types, ecosystem services, anthropogenic activity, or consistency in identifying important conservation areas. The purpose of this study was to identify hotspots to improve avian conservation efforts for Species of Greatest Conservation Need (SGCN) in the state of Idaho, United States. We evaluated multiple approaches to define hotspots and used a unique approach based on weighting species by their distribution size and conservation status to identify hotspot areas. All hotspot approaches identified bodies of water (Bear Lake, Grays Lake, and American Falls Reservoir) as important hotspots for Idaho avian SGCN, but we found that the weighted approach produced more congruent hotspot areas when compared to other hotspot approaches. To incorporate anthropogenic activity into hotspot analysis, we grouped species based on their sensitivity to specific human threats (i.e., urban development, agriculture, fire suppression, grazing, roads, and logging) and identified ecological sections within Idaho that may require specific conservation actions to address these human threats using the weighted approach. The Snake River Basalts and Overthrust Mountains ecological sections were important areas for potential implementation of conservation actions to conserve biodiversity. Our approach to identifying hotspots may be useful as part of a larger conservation strategy to aid land managers or local governments in applying conservation actions on the ground.

  16. A public health approach to preventing child abuse in low- and middle-income countries: a call for action.

    PubMed

    Skeen, Sarah; Tomlinson, Mark

    2013-01-01

    Violence against children is prevalent across all countries and cultures, with the burden of child injury and violence heaviest in low- and middle-income (LAMI) settings. There are several types of program to prevent child abuse, with family-based approaches to prevention being the most comprehensively researched and successful interventions in high-income settings. In LAMI countries, however, there is very little research evidence for the prevention of child abuse. We conducted a systematic search of relevant databases for studies published between 1995 and 2011 and the search revealed only one relevant study. There is thus a need for research into child maltreatment prevention in LAMI settings, taking account of local resources and contexts. In the light of the lack of evidence, we focus on two case studies that document the use of home visiting by community health workers perinatally to improve maternal and child outcomes. We propose four areas for action moving forward, including increased investment in early intervention and prevention programs, development of a research agenda that prioritizes prevention research, integration of implementation research into efforts to scale up interventions, and improving systematically collected information on child maltreatment.

  17. A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine

    PubMed Central

    Lee, Kuen-Haur; Lo, Hsiang-Ling; Tang, Wan-Chun; Hsiao, Heidi Hao-yun; Yang, Pei-Ming

    2014-01-01

    Berberine (BBR), a traditional Chinese herbal medicine, was shown to display anticancer activity. In this study, we attempted to provide a global view of the molecular pathways associated with its anticancer effect through a gene expression-based chemical approach. BBR-induced differentially expressed genes obtained from the Gene Expression Omnibus (GEO) at the National Center for Biotechnology Information (NCBI) were analyzed using the Connectivity Map (CMAP) database to compare similarities of gene expression profiles between BBR and CMAP compounds. Candidate compounds were further analyzed using the Search Tool for Interactions of Chemicals (STITCH) database to explore chemical-protein interactions. Results showed that BBR may inhibit protein synthesis, histone deacetylase (HDAC), or AKT/mammalian target of rapamycin (mTOR) pathways. Further analyses demonstrated that BBR inhibited global protein synthesis and basal AKT activity, and induced endoplasmic reticulum (ER) stress and autophagy, which was associated with activation of AMP-activated protein kinase (AMPK). However, BBR did not alter mTOR or HDAC activities. Interestingly, BBR induced the acetylation of α-tubulin, a substrate of HDAC6. In addition, the combination of BBR and SAHA, a pan-HDAC inhibitor, synergistically inhibited cell proliferation and induced cell cycle arrest. Our results provide novel insights into the mechanisms of action of BBR in cancer therapy. PMID:25227736

  18. Predictors of FIFA 11+ Implementation Intention in Female Adolescent Soccer: An Application of the Health Action Process Approach (HAPA) Model.

    PubMed

    McKay, Carly D; Merrett, Charlotte K; Emery, Carolyn A

    2016-07-07

    The Fédération Internationale de Football (FIFA) 11+ warm-up program is efficacious at preventing lower limb injury in youth soccer; however, there has been poor adoption of the program in the community. The purpose of this study was to determine the utility of the Health Action Process Approach (HAPA) behavior change model in predicting intention to use the FIFA 11+ in a sample of 12 youth soccer teams (coaches n = 10; 12-16 year old female players n = 200). A bespoke cross-sectional questionnaire measured pre-season risk perceptions, outcome expectancies, task self-efficacy, facilitators, barriers, and FIFA 11+ implementation intention. Most coaches (90.0%) and players (80.0%) expected the program to reduce injury risk but reported limited intention to use it. Player data demonstrated an acceptable fit to the hypothesized model (standardized root mean square residual (SRMR) = 0.08; root mean square of error of approximation (RMSEA) = 0.06 (0.047-0.080); comparative fit index (CFI) = 0.93; Tucker Lewis index (TLI) = 0.91) Task self-efficacy (β = 0.53, p ≤ 0.01) and outcome expectancies (β = 0.13 p ≤ 0.05) were positively associated with intention, but risk perceptions were not (β = -0.02). The findings suggest that the HAPA model is appropriate for use in this context, and highlight the need to target task self-efficacy and outcome expectancies in FIFA 11+ implementation strategies.

  19. [Constructivist evaluation, under an integrating and intersectoral approach, of actions of the Disque Idoso Project in Sobral (CE, Brazil)].

    PubMed

    Freitas, Cibelly Aliny Siqueira Lima; Teófilo, Tiago José Silveira

    2010-09-01

    The population aging in Brazil and in the world is a reason for an epidemic inquietude. So, the violence against senior people has been considered a problem of public health. This study takes as context the health need of seniors that suffer of violence, aiming to evaluate in a constructive way the Disque Idoso Project in Sobral (Ceará, Brazil). We used Furtado's Constructivist Method of Evaluation, which provides practices of participative evaluation. Trying to reach such perspective, we are guided by paths of the integrative approach (inter, multi and transdisciplinary) and intersectoral. We accomplished the focal groups with representatives of the sections of health, social assistance, justice and senior, the benefited by the project as well as others that contribute to its development. When interacting with the professionals that act in the project headquarters we understood that there is a fear in publishing their work, because there is not structure to enlarge the attendance. The group believes that the efficiency of its actions is limited due to the lack of transport and other professionals. For the professionals of the support social networks, the project should look for intersectoral performance, once it intends to reach a complete attendance. For the seniors, the project is quite valid and needs to be consolidated in the district.

  20. A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.

    PubMed

    Lee, Kuen-Haur; Lo, Hsiang-Ling; Tang, Wan-Chun; Hsiao, Heidi Hao-yun; Yang, Pei-Ming

    2014-09-17

    Berberine (BBR), a traditional Chinese herbal medicine, was shown to display anticancer activity. In this study, we attempted to provide a global view of the molecular pathways associated with its anticancer effect through a gene expression-based chemical approach. BBR-induced differentially expressed genes obtained from the Gene Expression Omnibus (GEO) at the National Center for Biotechnology Information (NCBI) were analyzed using the Connectivity Map (CMAP) database to compare similarities of gene expression profiles between BBR and CMAP compounds. Candidate compounds were further analyzed using the Search Tool for Interactions of Chemicals (STITCH) database to explore chemical-protein interactions. Results showed that BBR may inhibit protein synthesis, histone deacetylase (HDAC), or AKT/mammalian target of rapamycin (mTOR) pathways. Further analyses demonstrated that BBR inhibited global protein synthesis and basal AKT activity, and induced endoplasmic reticulum (ER) stress and autophagy, which was associated with activation of AMP-activated protein kinase (AMPK). However, BBR did not alter mTOR or HDAC activities. Interestingly, BBR induced the acetylation of α-tubulin, a substrate of HDAC6. In addition, the combination of BBR and SAHA, a pan-HDAC inhibitor, synergistically inhibited cell proliferation and induced cell cycle arrest. Our results provide novel insights into the mechanisms of action of BBR in cancer therapy.

  1. Using the health action process approach to predict and improve health outcomes in individuals with type 2 diabetes mellitus

    PubMed Central

    MacPhail, Mariana; Mullan, Barbara; Sharpe, Louise; MacCann, Carolyn; Todd, Jemma

    2014-01-01

    Background The purpose of this study was to explore the predictive utility of the Health Action Process Approach (HAPA) and test a HAPA-based healthy eating intervention, in adults with type 2 diabetes mellitus. Materials and methods The study employed a prospective, randomized, controlled trial design. The 4-month intervention consisted of self-guided HAPA-based workbooks in addition to two telephone calls to assist participants with the program implementation, and was compared to “treatment as usual”. Participants (n=87) completed health measures (diet, body mass index [BMI], waist circumference, blood pressure, blood glucose levels, lipid levels, and diabetes distress) and HAPA measures prior to the intervention and again upon completion 4 months later. Results The overall HAPA model predicted BMI, although only risk awareness and recovery self-efficacy were significant independent contributors. Risk awareness, intentions, and self-efficacy were also independent predictors of health outcomes; however, the HAPA did not predict healthy eating. No significant time × condition interaction effects were found for diet or any HAPA outcome measures. Conclusion Despite the success of HAPA in predicting health outcomes for those with type 2 diabetes mellitus, the intervention was unsuccessful in changing healthy eating or any of the other measured variables, and alternative low-cost health interventions for those with type 2 diabetes mellitus should be explored. PMID:25342914

  2. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 408: Bomblet Target Area Tonopah Test Range (TTR), Nevada, Revision 1

    SciTech Connect

    Mark Krauss

    2010-03-01

    This Streamlined Approach for Environmental Restoration Plan addresses the actions needed to achieve closure of Corrective Action Unit (CAU) 408, Bomblet Target Area (TTR). Corrective Action Unit 408 is located at the Tonopah Test Range and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order. Corrective Action Unit 408 comprises Corrective Action Site TA-55-002-TAB2, Bomblet Target Areas. Clean closure of CAU 408 will be accomplished by removal of munitions and explosives of concern within seven target areas and potential disposal pits. The target areas were used to perform submunitions related tests for the U.S. Department of Energy (DOE). The scope of CAU 408 is limited to submunitions released from DOE activities. However, it is recognized that the presence of other types of unexploded ordnance and munitions may be present within the target areas due to the activities of other government organizations. The CAU 408 closure activities consist of: • Clearing bomblet target areas within the study area. • Identifying and remediating disposal pits. • Collecting verification samples. • Performing radiological screening of soil. • Removing soil containing contaminants at concentrations above the action levels. Based on existing information, contaminants of potential concern at CAU 408 include unexploded submunitions, explosives, Resource Conservation Recovery Act metals, and depleted uranium. Contaminants are not expected to be present in the soil at concentrations above the action levels; however, this will be determined by radiological surveys and verification sample results.

  3. Streamlined approach for environmental restoration (SAFER) plan for corrective action unit 412: clean slate I plutonium dispersion (TTR) tonopah test range, Nevada, revision 0

    SciTech Connect

    Matthews, Patrick K.

    2015-04-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 412. CAU 412 is located on the Tonopah Test Range and consists of a single corrective action site (CAS), TA-23-01CS, Pu Contaminated Soil. There is sufficient information and historical documentation from previous investigations and the 1997 interim corrective action to recommend closure of CAU 412 using the SAFER process. Based on existing data, the presumed corrective action for CAU 412 is clean closure. However, additional data will be obtained during a field investigation to document and verify the adequacy of existing information and determine whether the CAU 412 closure objectives have been achieved. This SAFER Plan provides the methodology to gather the necessary information for closing the CAU.The following summarizes the SAFER activities that will support the closure of CAU 412:• Collect environmental samples from designated target populations to confirm or disprove the presence of contaminants of concern (COCs) as necessary to supplement existing information.• If no COCs are present, establish clean closure as the corrective action. • If COCs are present, the extent of contamination will be defined and further corrective actions will be evaluated with the stakeholders (NDEP, USAF).• Confirm the preferred closure option is sufficient to protect human health and the environment.

  4. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 398: Area 25 Spill Sites, Nevada Test Site, Nevada

    SciTech Connect

    K. B. Campbell

    2001-11-01

    This Streamlined Approach for Environmental Restoration (SAFER) plan addresses the activities necessary to close Corrective Action Unit (CAU) 398: Area 25 Spill Sites. CAU 398, located in Area 25 of the Nevada Test Site, is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996), and consists of the following 13 Corrective Action Sites (CASs) (Figure 1): (1) CAS 25-44-01 , a fuel spill on soil that covers a concrete pad. The origins and use of the spill material are unknown, but the spill is suspected to be railroad bedding material. (2) CAS 25-44-02, a spill of liquid to the soil from leaking drums. (3) CAS 25-44-03, a spill of oil from two leaking drums onto a concrete pad and surrounding soil. (4) CAS 25-44-04, a spill from two tanks containing sulfuric acid and sodium hydroxide used for a water demineralization process. (5) CAS 25-25-02, a fuel or oil spill from leaking drums that were removed in 1992. (6) CAS 25-25-03, an oil spill adjacent to a tipped-over drum. The source of the drum is not listed, although it is noted that the drum was removed in 1991. (7) CAS 25-25-04, an area on the north side of the Engine-Maintenance, Assembly, and Disassembly (E-MAD) facility, where oils and cooling fluids from metal machining operations were poured directly onto the ground. (8) CAS 25-25-05, an area of oil and/or hydraulic fluid spills beneath the heavy equipment once stored there. (9) CAS 25-25-06, an area of diesel fuel staining beneath two generators that have since been removed. (10) CAS 25-25-07, an area of hydraulic oil spills associated with a tunnel-boring machine abandoned inside X-Tunnel. (11) CAS 25-25-08, an area of hydraulic fluid spills associated with a tunnel-boring machine abandoned inside Y-Tunnel. (12) CAS 25-25-16, a diesel fuel spill from an above-ground storage tank located near Building 3320 at Engine Test Stand-1 (ETS-1) that was removed in 1998. (13) CAS 25-25-17, a hydraulic oil spill

  5. The Health Action Process Approach as a Motivational Model of Dietary Self-Management for People with Multiple Sclerosis: A Path Analysis

    ERIC Educational Resources Information Center

    Chiu, Chung-Yi; Lynch, Ruth Torkelson; Chan, Fong; Rose, Lindsey

    2012-01-01

    The main objective of this study was to evaluate the health action process approach (HAPA) as a motivational model for dietary self-management for people with multiple sclerosis (MS). Quantitative descriptive research design using path analysis was used. Participants were 209 individuals with MS recruited from the National MS Society and a…

  6. Re-Imagining "Bildung Zur Humanität": How I Developed the Dialogos Approach to Practical Philosophy through Action Inquiry Research

    ERIC Educational Resources Information Center

    Helskog, Guro Hansen

    2015-01-01

    This paper presents an account of how I developed the Dialogos approach to practical philosophy through action inquiry research. The process of development is understood as a contribution to the reconstruction of the notion "Bildung zur Humanität" as an ideal in education. Core perspectives, traditions and purposes involved in the action…

  7. The interaction of approach-alcohol action tendencies, working memory capacity, and current task goals predicts the inability to regulate drinking behavior.

    PubMed

    Sharbanee, Jason M; Stritzke, Werner G K; Wiers, Reinout W; Young, Paul; Rinck, Mike; MacLeod, Colin

    2013-09-01

    The inability to regulate alcohol consumption has been attributed to an imbalance between stimulus-driven behavioral biases, or action tendencies, and the ability to exert goal-directed control, or working memory capacity (WMC). Previous research assessing the interaction between these variables has not considered the effect of whether individuals' current goals or task demands require goal-directed control. Our aim was to examine the potential interaction of appetitive action tendencies and the ability to exert control over these action tendencies as a function of whether task demands require applying control for successful task completion. Two groups of social drinkers (n = 40 per group) who differed in their ability to regulate their alcohol consumption completed a novel variant of the Approach-Avoidance Task (AAT), which separately assessed approach and avoid trials. The approach and avoidance responses differentially require goal-directed control, depending on whether the task-relevant response is incongruent with the stimulus-driven action tendency. Results indicated that (a) group differences in AAT indices were only observed on trials that required an avoidance movement, which are trials where the task-relevant response would be incongruent with an approach action tendency, and (b) the extent of the group differences for these avoidance trials was moderated by individual differences in WMC, such that problem drinkers with lower WMC showed greater behavioral bias toward alcohol than those with higher WMC. These findings suggest that difficulties in regulating alcohol consumption arise from a complex interaction of action-tendencies, WMC, and current goals or task demands.

  8. Join Us in a Participatory Approach to Training, Learning & Production. A Practical Guide to the Action Training Model.

    ERIC Educational Resources Information Center

    Frings, A.; And Others

    This handbook is intended to help trainers and development workers plan and conduct training programs based on the Action Training Model (ATM). The ATM combines training with action and learning with production by building upon participants' knowledge and learning needs and involving participants in a process of active learning and cooperative…

  9. Predictors of FIFA 11+ Implementation Intention in Female Adolescent Soccer: An Application of the Health Action Process Approach (HAPA) Model

    PubMed Central

    McKay, Carly D.; Merrett, Charlotte K.; Emery, Carolyn A.

    2016-01-01

    The Fédération Internationale de Football (FIFA) 11+ warm-up program is efficacious at preventing lower limb injury in youth soccer; however, there has been poor adoption of the program in the community. The purpose of this study was to determine the utility of the Health Action Process Approach (HAPA) behavior change model in predicting intention to use the FIFA 11+ in a sample of 12 youth soccer teams (coaches n = 10; 12–16 year old female players n = 200). A bespoke cross-sectional questionnaire measured pre-season risk perceptions, outcome expectancies, task self-efficacy, facilitators, barriers, and FIFA 11+ implementation intention. Most coaches (90.0%) and players (80.0%) expected the program to reduce injury risk but reported limited intention to use it. Player data demonstrated an acceptable fit to the hypothesized model (standardized root mean square residual (SRMR) = 0.08; root mean square of error of approximation (RMSEA) = 0.06 (0.047–0.080); comparative fit index (CFI) = 0.93; Tucker Lewis index (TLI) = 0.91) Task self-efficacy (β = 0.53, p ≤ 0.01) and outcome expectancies (β = 0.13 p ≤ 0.05) were positively associated with intention, but risk perceptions were not (β = −0.02). The findings suggest that the HAPA model is appropriate for use in this context, and highlight the need to target task self-efficacy and outcome expectancies in FIFA 11+ implementation strategies. PMID:27399746

  10. Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach

    PubMed Central

    Karathanos, Thomas V.; Boyle, Patrick M.; Trayanova, Natalia A.

    2014-01-01

    Aims Diseases that abbreviate the cardiac action potential (AP) by increasing the strength of repolarizing transmembrane currents are highly arrhythmogenic. It has been proposed that optogenetic tools could be used to restore normal AP duration (APD) in the heart under such disease conditions. This study aims to evaluate the efficacy of an optogenetic treatment modality for prolonging pathologically shortened APs in a detailed computational model of short QT syndrome (SQTS) in the human atria, and compare it to drug treatment. Methods and results We used a human atrial myocyte model with faster repolarization caused by SQTS; light sensitivity was inscribed via the presence of channelrhodopsin-2 (ChR2). We conducted simulations in single cells and in a magnetic resonance imaging-based model of the human left atrium (LA). Application of an appropriate optical stimulus to a diseased cell dynamically increased APD, producing an excellent match to control AP (<1.5 mV deviation); treatment of a diseased cell with an AP-prolonging drug (chloroquine) also increased APD, but the match to control AP was worse (>5 mV deviation). Under idealized conditions in the LA (uniform ChR2-expressing cell distribution, no light attenuation), optogenetics-based therapy outperformed chloroquine treatment (APD increased to 87% and 81% of control). However, when non-uniform ChR2-expressing cell distribution and light attenuation were incorporated, optogenetics-based treatment was less effective (APD only increased to 55%). Conclusion This study demonstrates proof of concept for optogenetics-based treatment of diseases that alter atrial AP shape. We identified key practical obstacles intrinsic to the optogenetic approach that must be overcome before such treatments can be realized. PMID:25362173

  11. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 553: Areas 19, 20 Mud Pits and Cellars, Nevada Test Site, Nevada, Rev. No. 0

    SciTech Connect

    Boehlecke, Robert F.

    2006-11-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the closure of Corrective Action Unit (CAU) 553: Areas 19, 20 Mud Pits and Cellars, Nevada Test Site (NTS), Nevada. It has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense. A SAFER may be performed when the following criteria are met: (1) Conceptual corrective actions are clearly identified (although some degree of investigation may be necessary to select a specific corrective action before completion of the Corrective Action Investigation [CAI]); (2) Uncertainty of the nature, extent, and corrective action must be limited to an acceptable level of risk; (3) The SAFER Plan includes decision points and criteria for making data quality objective (DQO) decisions. The purpose of the investigation will be to document and verify the adequacy of existing information; to affirm the decision for clean closure, closure in place, or no further action; and to provide sufficient data to implement the corrective action. The actual corrective action selected will be based on characterization activities implemented under this SAFER Plan. This SAFER Plan identifies decision points developed in cooperation with the Nevada Department of Environmental Protection (NDEP), where the DOE, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) will reach consensus with the NDEP before beginning the next phase of work. Corrective Action Unit 553 is located in Areas 19 and 20 of the NTS, approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1-1). Corrective Action Unit 553 is comprised of the four Corrective Action Sites (CASs) shown on Figure 1-1 and listed below: 19-99-01, Mud Spill; 19-99-11, Mud Spill; 20-09-09, Mud Spill; and 20-99-03, Mud Spill. There is sufficient information and process

  12. Applicability of action planning and coping planning to dental flossing among Norwegian adults: a confirmatory factor analysis approach.

    PubMed

    Astrøm, Anne Nordrehaug

    2008-06-01

    Using a prospective design and a representative sample of 25-yr-old Norwegians, this study hypothesized that action planning and coping planning will add to the prediction of flossing at 4 wk of follow-up over and above the effect of intention and previous flossing. This study tested the validity of a proposed 3-factor structure of the measurement model of intention, action planning, and coping planning and for its invariance across gender. A survey was conducted in three Norwegian counties, and 1,509 out of 8,000 randomly selected individuals completed questionnaires assessing the constructs of action planning and coping planning related to daily flossing. A random subsample of 500 participants was followed up at 4 wk with a telephone interview to assess flossing. Confirmatory factor analysis (CFA) confirmed the proposed 3-factor model after respecification. Although the chi-square test was statistically significant [chi(2) = 58.501, degrees of freedom (d.f.) = 17), complementary fit indices were satisfactory [goodness-of-fit index (GFI) = 0.99, root mean squared error of approximation (RMSEA) = 0.04]. Multigroup CFA provided evidence of complete invariance of the measurement model across gender. After controlling for previous flossing, intention (beta = 0.08) and action planning (beta = 0.11) emerged as independent predictors of subsequent flossing, accounting for 2.3% of its variance. Factorial validity of intention, action planning and coping planning, and the validity of action planning in predicting flossing prospectively, was confirmed by the present study.

  13. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 124: Storage Tanks, Nevada Test Site, Nevada (Draft), Revision 0

    SciTech Connect

    Alfred Wickline

    2007-04-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for Corrective Action Unit (CAU) 124, Areas 8, 15, and 16 Storage Tanks, identified in the Federal Facility Agreement and Consent Order. Corrective Action Unit 124 consists of five Corrective Action Sites (CASs) located in Areas 8, 15, and 16 of the Nevada Test Site as follows: • 08-02-01, Underground Storage Tank • 15-02-01, Irrigation Piping • 16-02-03, Underground Storage Tank • 16-02-04, Fuel Oil Piping • 16-99-04, Fuel Line (Buried) and UST This plan provides the methodology of field activities necessary to gather information to close each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 124 using the SAFER process.

  14. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 113: Reactor Maintenance, Assembly, and Disassembly Building Nevada Test Site, Nevada

    SciTech Connect

    J. L. Smith

    2001-01-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the action necessary for the closure in place of Corrective Action Unit (CAU) 113 Area 25 Reactor Maintenance, Assembly, and Disassembly Facility (R-MAD). CAU 113 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) (NDEP, 1996). The CAU is located in Area 25 of the Nevada Test Site (NTS) and consists of Corrective Action Site (CAS) 25-04-01, R-MAD Facility (Figures 1-2). This plan provides the methodology for closure in place of CAU 113. The site contains radiologically impacted and hazardous material. Based on preassessment field work, there is sufficient process knowledge to close in place CAU 113 using the SAFER process. At a future date when funding becomes available, the R-MAD Building (25-3110) will be demolished and inaccessible radiologic waste will be properly disposed in the Area 3 Radiological Waste Management Site (RWMS).

  15. Streamlined approach for environmental restoration plan for corrective action unit 430, buried depleted uranium artillery round No. 1, Tonopah test range

    SciTech Connect

    1996-09-01

    This plan addresses actions necessary for the restoration and closure of Corrective Action Unit (CAU) No. 430, Buried Depleted Uranium (DU) Artillery Round No. 1 (Corrective Action Site No. TA-55-003-0960), a buried and unexploded W-79 Joint Test Assembly (JTA) artillery test projectile with high explosives (HE), at the U.S. Department of Energy, Nevada Operations Office (DOE/NV) Tonopah Test Range (TTR) in south-central Nevada. It describes activities that will occur at the site as well as the steps that will be taken to gather adequate data to obtain a notice of completion from Nevada Division of Environmental Protection (NDEP). This plan was prepared under the Streamlined Approach for Environmental Restoration (SAFER) concept, and it will be implemented in accordance with the Federal Facility Agreement and Consent Order (FFACO) and the Resource Conservation and Recovery Act (RCRA) Industrial Sites Quality Assurance Project Plan.

  16. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 117: Area 26 Pluto Disassembly Facility, Nevada Test Site, Nevada With Errata Sheets, Revision 0

    SciTech Connect

    Pat Matthews

    2007-09-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 117, Pluto Disassembly Facility, identified in the Federal Facility Agreement and Consent Order. Corrective Action Unit 117 consists of one Corrective Action Site (CAS), CAS 26-41-01, located in Area 26 of the Nevada Test Site. This plan provides the methodology for field activities needed to gather the necessary information for closing CAS 26-41-01. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 117 using the SAFER process. Additional information will be obtained by conducting a field investigation before finalizing the appropriate corrective action for this CAS. The results of the field investigation will support a defensible recommendation that no further corrective action is necessary following SAFER activities. This will be presented in a Closure Report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval. The site will be investigated to meet the data quality objectives (DQOs) developed on June 27, 2007, by representatives of NDEP; U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and National Security Technologies, LLC. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAS 26-41-01 in CAU 117.

  17. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 411. Double Tracks Plutonium Dispersion (Nellis), Nevada Test and Training Range, Nevada, Revision 0

    SciTech Connect

    Matthews, Patrick K.

    2015-03-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 411, Double Tracks Plutonium Dispersion (Nellis). CAU 411 is located on the Nevada Test and Training Range and consists of a single corrective action site (CAS), NAFR-23-01, Pu Contaminated Soil. There is sufficient information and historical documentation from previous investigations and the 1996 interim corrective action to recommend closure of CAU 411 using the SAFER process. Based on existing data, the presumed corrective action for CAU 411 is clean closure. However, additional data will be obtained during a field investigation to document and verify the adequacy of existing information, and to determine whether the CAU 411 closure objectives have been achieved. This SAFER Plan provides the methodology to gather the necessary information for closing the CAU. The results of the field investigation will be presented in a closure report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval. The site will be investigated based on the data quality objectives (DQOs) developed on November 20, 2014, by representatives of NDEP, the U.S. Air Force (USAF), and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine whether CAU 411 closure objectives have been achieved. The following text summarizes the SAFER activities that will support the closure of CAU 411; Collect environmental samples from designated target populations to confirm or disprove the presence of contaminants of concern (COCs) as necessary to supplement existing information; If COCs are no longer present, establish clean closure as the corrective action; If COCs are present, the extent of contamination will be defined and further corrective actions

  18. Development of nurses' abilities to reflect on how to create good caring relationships with patients in palliative care: an action research approach.

    PubMed

    Bergdahl, Elisabeth; Benzein, Eva; Ternestedt, Britt-Marie; Andershed, Birgitta

    2011-06-01

    Development of nurses' abilities to reflect on how to create good caring relationships with patients in palliative care: an action research approach In this paper we present an action research process aimed at enhancing nurses' abilities to reflect on how to create good caring relationships with patients in advanced home care. Another aim was to examine the usefulness of an emerging theory, derived from results from a previous study. The request for this project to take place came from an advanced home care unit which had received complaints concerning patients in the palliative phase. The action performed was clinical supervision, structured around abilities that nurses need in order to create good caring relationships. During the action research process 42 narratives were analysed by the participating group. Three different data collections were carried out and analysed with qualitative content analysis in a triangulation procedure. The emerging theory was found to be useful and was also refined. The nurses reported that they felt strengthened and had developed their ability to reflect over good caring relationships. Some changes to practice were carried out by the participating nurses. The result also indicates that action research can be helpful in examining the usefulness of an emerging theory.

  19. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 575: Area 15 Miscellaneous Sites, Nevada National Security Site, Nevada

    SciTech Connect

    Matthews, Patrick

    2014-12-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 575, Area 15 Miscellaneous Sites, identified in the Federal Facility Agreement and Consent Order (FFACO). CAU 575 comprises the following four corrective action sites (CASs) located in Area 15 of the Nevada National Security Site: 15-19-02, Waste Burial Pit, 15-30-01, Surface Features at Borehole Sites, 15-64-01, Decontamination Area, 15-99-03, Aggregate Plant This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 575 using the SAFER process. Additional information will be obtained by conducting a field investigation to document and verify the adequacy of existing information, to affirm the predicted corrective action decisions, and to provide sufficient data to implement the corrective actions. This will be presented in a closure report that will be prepared and submitted to the Nevada Division of Environmental Protection (NDEP) for review and approval.

  20. Anger fosters action. Fast responses in a motor task involving approach movements toward angry faces and bodies

    PubMed Central

    de Valk, Josje M.; Wijnen, Jasper G.; Kret, Mariska E.

    2015-01-01

    Efficiently responding to others’ emotions, especially threatening expressions such as anger and fear, can have great survival value. Previous research has shown that humans have a bias toward threatening stimuli. Most of these studies focused on facial expressions, yet emotions are expressed by the whole body, and not just by the face. Body language contains a direct action component, and activates action preparation areas in the brain more than facial expressions. Hence, biases toward threat may be larger following threatening bodily expressions as compared to facial expressions. The current study investigated reaction times of movements directed toward emotional bodies and faces. For this purpose, a new task was developed where participants were standing in front of a computer screen on which angry, fearful, and neutral faces and bodies were presented which they had to touch as quickly as possible. Results show that participants responded faster to angry than to neutral stimuli, regardless of the source (face or body). No significant difference was observed between fearful and neutral stimuli, demonstrating that the threat bias was not related to the negativity of the stimulus, but likely to the directness of the threat in relation to the observer. Whereas fearful stimuli might signal an environmental threat that requires further exploration before action, angry expressions signal a direct threat to the observer, asking for immediate action. This study provides a novel and implicit method to directly test the speed of actions toward emotions from the whole body. PMID:26388793

  1. Understanding African American Women’s Decisions to Buy and Eat Dark Green Leafy Vegetables: An Application of the Reasoned Action Approach

    PubMed Central

    Sheats, Jylana L.; Middlestadt, Susan E.; Ona, Fernando F.; Juarez, Paul D.; Kolbe, Lloyd J.

    2014-01-01

    Objective Examine intentions to buy and eat dark green leafy vegetables (DGLV). Design Cross-sectional survey assessing demographics, behavior, intention, and Reasoned Action Approach constructs (attitude, perceived norm, self-efficacy). Setting Marion County, Indiana. Participants African American women responsible for buying and preparing household food. Main Outcome Measure(s) Reasoned Action Approach constructs explaining intentions to buy and eat DGLV. Analysis Summary statistics, Pearson correlations, and multiple regression analyses. Results Among participants (n = 410, mean age = 43 y), 76% and 80%, respectively, reported buying and eating DGLV in the past week. Mean consumption was 1.5 cups in the past 3 days. Intentions to buy (r = 0.20, P < .001) and eat (r = 0.23, P < .001) DGLV were positively associated with consumption. Reasoned Action Approach constructs explained 71.2% of the variance in intention to buy, and 60.9% of the variance in intention to eat DGLV. Attitude (β = .63) and self-efficacy (β = .24) related to buying and attitude (β = .60) and self-efficacy (β = .23) related to eating DGLV explained significant amounts of variance in intentions to buy and eat more DGLV. Perceived norm was unrelated to either intention to buy or eat DGLV. Conclusions and Implications Interventions designed for this population of women should aim to improve DGLV-related attitudes and self-efficacy. PMID:24021457

  2. Community-Involved Learning to Expand Possibilities for Vulnerable Children: A Critical Communicative, Sen's Capability, and Action Research Approach

    ERIC Educational Resources Information Center

    Kim, Kyung Hi

    2014-01-01

    This research, based on a case study of vulnerable children in Korea, used a mixed methods transformative approach to explore strategies to support and help disadvantaged children. The methodological approach includes three phases: a mixed methods contextual analysis, a qualitative dominant analysis based on Sen's capability approach and critical…

  3. A Non-Blaming Chance and Action Approach to Therapy with Sexually Explicit Media Overuse: A Case Study

    ERIC Educational Resources Information Center

    Wernik, Uri

    2012-01-01

    In this clinical presentation a non-blaming, non-judgmental approach to overuse of sexually explicit media (SEM) is introduced. This approach normalizes the problem and sees it in the context of evolution and market forces. It is claimed that such an approach contributes to change and strengthens the therapeutic alliance. A new technique utilizing…

  4. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 540: Spill Sites Nevada Test Site, Nevada, Rev. No.: 0, with Errata

    SciTech Connect

    Pastor, Laura

    2005-11-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for Corrective Action Unit (CAU) 540, Spill Sites, identified in the ''Federal Facility Agreement and Consent Order''. Corrective Action Unit 540 consists of the nine following Corrective Action Sites (CASs) located in Areas 12 and 19 of the Nevada Test Site: (1) 12-44-01, ER 12-1, Well Site Release; (2) 12-99-01, Oil Stained Dirt; (3) 19-25-02, Oil Spill; (4) 19-25-04, Oil Spill; (5) 19-25-05, Oil Spill; (6) 19-25-06, Oil Spill; (7) 19-25-07, Oil Spill; (8) 19-25-08, Oil Spills (3); and (9) 19-44-03, U-19bf Drill Site Release. This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 540 using the SAFER process. The data quality objective process developed for this CAU identified the following expected closure options: (1) investigation and confirmation that no contamination exists above the final action levels (FALs), leading to a no further action declaration; (2) characterization of the nature and extent of contamination, leading to closure in place with use restrictions; or (3) clean closure by remediation and verification. The expected closure options were selected based on available information including contaminants of potential concern (COPC), future land use, and assumed risks. A decision flow process was developed to define an approach necessary to achieve closure. There are two decisions that need to be resolved for closure. Decision I is to conduct an investigation to determine whether COPCs are present in concentrations exceeding the FALs. If COPCs are found to be present above FALs, excavation of the contaminated material will occur with the collection of confirmation samples to ensure

  5. Effects of Different Forms of Tutor Action in a Conditional Reasoning Task: An Experimental Approach to the Tutorial Dialogue

    ERIC Educational Resources Information Center

    Olry-Louis. Isabelle

    2009-01-01

    This study investigated how different forms of tutor action influenced novice students' performance on the Wason selection task, and how the students perceived the situation. In the control condition, the tutor provided supportive feedback which was minimal in terms of content (CG), in contrast to help in the form of directives (IM) or questions…

  6. Collaborative Action Research Approach Promoting Professional Development for Teachers of Students with Visual Impairment in Assistive Technology

    ERIC Educational Resources Information Center

    Argyropoulos, Vassilios; Nikolaraizi, Magda; Tsiakali, Thomai; Kountrias, Polychronis; Koutsogiorgou, Sofia-Marina; Martos, Aineias

    2014-01-01

    This paper highlights the framework and discusses the results of an action research project which aimed to facilitate the adoption of assistive technology devices and specialized software by teachers of students with visual impairment via a digital educational game, developed specifically for this project. The persons involved in this…

  7. "What If? As If", An Approach to Action Research Practice: Becoming-Different in School-Age Childcare

    ERIC Educational Resources Information Center

    Kane, Eva

    2015-01-01

    When doing research, or for that matter working in school-age childcare, the researcher/teacher is required to develop a plan for her/his work in spite of knowing that unexpected things will happen. This article aims to explore the relationship between the process of planning and unexpected events in childcare practice and action research. The…

  8. Influencing Teacher Efficacy through Action Research: The Implementation of an Embedded, Standards-Based Professional Development Approach

    ERIC Educational Resources Information Center

    Williams-Payne, Taisha C.

    2013-01-01

    This action research study examined the implementation and impact of a job-embedded professional development intervention that included professional learning community (PLC) sessions and individualized feedback and coaching. Participants in the study were eight high school teachers who had historically demonstrated poor classroom performance and…

  9. Exploring Constructivist Social Learning Practices in Aiding Russian-Speaking Teachers to Learn Estonian: An Action Research Approach

    ERIC Educational Resources Information Center

    Kiilo, Tatjana; Kutsar, Dagmar

    2012-01-01

    Based on appreciative inquiry and threshold concepts from an intercultural learning perspective, the article makes insights into the constructivist social learning practice of Estonian language learning amongst Russian-speaking teachers in Estonia. The application of educational action research methodology, more specifically that of Bridget…

  10. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 114: Area 25 EMAD Facility Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Mark Burmeister

    2009-08-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 114, Area 25 EMAD Facility, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 114 comprises the following corrective action sites (CASs) located in Area 25 of the Nevada Test Site: • 25-41-03, EMAD Facility • 25-99-20, EMAD Facility Exterior Releases This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 114 using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. It is anticipated that the results of the field investigation and implementation of a corrective action of clean closure will support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place. This will be presented in a closure report that will be prepared and submitted to NDEP for review and approval. The sites will be investigated based on the data quality objectives (DQOs) developed on April 30, 2009, by representatives of NDEP; U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and National Security Technologies, LLC. The DQO process was used to identify and define the type, amount, and quality of data

  11. Exploring the bases for a mixed reality stroke rehabilitation system, Part I: A unified approach for representing action, quantitative evaluation, and interactive feedback

    PubMed Central

    2011-01-01

    Background Although principles based in motor learning, rehabilitation, and human-computer interfaces can guide the design of effective interactive systems for rehabilitation, a unified approach that connects these key principles into an integrated design, and can form a methodology that can be generalized to interactive stroke rehabilitation, is presently unavailable. Results This paper integrates phenomenological approaches to interaction and embodied knowledge with rehabilitation practices and theories to achieve the basis for a methodology that can support effective adaptive, interactive rehabilitation. Our resulting methodology provides guidelines for the development of an action representation, quantification of action, and the design of interactive feedback. As Part I of a two-part series, this paper presents key principles of the unified approach. Part II then describes the application of this approach within the implementation of the Adaptive Mixed Reality Rehabilitation (AMRR) system for stroke rehabilitation. Conclusions The accompanying principles for composing novel mixed reality environments for stroke rehabilitation can advance the design and implementation of effective mixed reality systems for the clinical setting, and ultimately be adapted for home-based application. They furthermore can be applied to other rehabilitation needs beyond stroke. PMID:21875441

  12. Putting Action in Perspective

    ERIC Educational Resources Information Center

    Lozano, Sandra C.; Hard, Bridgette Martin; Tversky, Barbara

    2007-01-01

    Embodied approaches to cognition propose that our own actions influence our understanding of the world. Do other people's actions also have this influence? The present studies show that perceiving another person's actions changes the way people think about objects in a scene. In Study 1, participants viewed a photograph and answered a question…

  13. A Dynamic Network Approach to the Assessment of Terrorist Groups and the Impact of Alternative Courses of Action

    DTIC Science & Technology

    2006-10-01

    courses of action ORA Statistical analysis of dynamic networks AutoMap Automated extraction of network from texts DyNet Simulation of dynamic...networks from texts, ORA for analyzing the extracted networks, and DyNet for what-if reasoning about the networks (see figure 1). Each of these...actors, groups, knowledge, resources, etc. that influence and are influenced by that node. DyNet is a multi-agent network simulation package for

  14. A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin

    PubMed Central

    Wright, Elise P.; Padula, Matthew P.; Higgins, Vincent J.; Aldrich-Wright, Janice R.; Coorssen, Jens R.

    2014-01-01

    Many clinically available anticancer compounds are designed to target DNA. This commonality of action often yields overlapping cellular response mechanisms and can thus detract from drug efficacy. New compounds are required to overcome resistance mechanisms that effectively neutralise compounds like cisplatin and those with similar chemical structures. Studies have shown that 56MESS is a novel compound which, unlike cisplatin, does not covalently bind to DNA, but is more toxic to many cell lines and active against cisplatin-resistant cells. Furthermore, a transcriptional study of 56MESS in yeast has implicated iron and copper metabolism as well as the general yeast stress response following challenge with 56MESS. Beyond this, the cytotoxicity of 56MESS remains largely uncharacterised. Here, yeast was used as a model system to facilitate a systems-level comparison between 56MESS and cisplatin. Preliminary experiments indicated that higher concentrations than seen in similar studies be used. Although a DNA interaction with 56MESS had been theorized, this work indicated that an effect on protein synthesis/ degradation was also implicated in the mechanism(s) of action of this novel anticancer compound. In contrast to cisplatin, the different mechanisms of action that are indicated for 56MESS suggest that this compound could overcome cisplatin resistance either as a stand-alone treatment or a synergistic component of therapeutics. PMID:28250393

  15. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 484: Surface Debris, Waste Sites, and Burn Area, Tonopah Test Range, Nevada

    SciTech Connect

    Bechel Nevada

    2004-05-01

    This Streamlined Approach for Environmental Restoration plan details the activities necessary to close Corrective Action Unit (CAU) 484: Surface Debris, Waste Sites, and Burn Area (Tonopah Test Range). CAU 484 consists of sites located at the Tonopah Test Range, Nevada, and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order. CAU 484 consists of the following six Corrective Action Sites: (1) CAS RG-52-007-TAML, Davis Gun Penetrator Test; (2) CAS TA-52-001-TANL, NEDS Detonation Area; (3) CAS TA-52-004-TAAL, Metal Particle Dispersion Test; (4) CAS TA-52-005-TAAL, Joint Test Assembly DU Sites; (5) CAS TA-52-006-TAPL, Depleted Uranium Site; and (6) CAS TA-54-001-TANL, Containment Tank and Steel Structure

  16. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 118: Area 27 Super Kukla Facility, Nevada Test Site, Nevada, Rev. No.: 1

    SciTech Connect

    David Strand

    2006-09-01

    This Streamlined Approach for Environmental Restoration (SAFER) plan addresses closure for Corrective Action Unit (CAU) 118, Area 27 Super Kukla Facility, identified in the ''Federal Facility Agreement and Consent Order''. Corrective Action Unit 118 consists of one Corrective Action Site (CAS), 27-41-01, located in Area 27 of the Nevada Test Site. Corrective Action Site 27-41-01 consists of the following four structures: (1) Building 5400A, Reactor High Bay; (2) Building 5400, Reactor Building and access tunnel; (3) Building 5410, Mechanical Building; and (4) Wooden Shed, a.k.a. ''Brock House''. This plan provides the methodology for field activities needed to gather the necessary information for closing the CAS. There is sufficient information and process knowledge from historical documentation and site confirmation data collected in 2005 and 2006 to recommend closure of CAU 118 using the SAFER process. The Data Quality Objective process developed for this CAU identified the following expected closure option: closure in place with use restrictions. This expected closure option was selected based on available information including contaminants of potential concern, future land use, and assumed risks. There are two decisions that need to be answered for closure. Decision I is to determine the nature of contaminants of concern in environmental media or potential source material that could impact human health or the environment. Decision II is to determine whether or not sufficient information has been obtained to confirm that closure objectives were met. This decision includes determining whether the extent of any contamination remaining on site has been defined, and whether actions have been taken to eliminate exposure pathways.

  17. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 539: Area 25 and Area 26 Railroad Tracks, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Mark Krauss

    2010-06-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 539, Areas 25 and 26 Railroad Tracks, as identified in the Federal Facility Agreement and Consent Order (FFACO). A modification to the FFACOwas approved in May 2010 to transfer the two Railroad Tracks corrective action sites (CASs) from CAU 114 into CAU539. The two CASs are located in Areas 25 and 26 of the Nevada Test Site: • 25-99-21, Area 25 Railroad Tracks • 26-99-05, Area 26 Railroad Tracks This plan provides the methodology for field activities needed to gather the necessary information for closing the two CASs. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of the CAU 539 Railroad Tracks CASs using the SAFER process. Additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. The results of the field investigation should support a defensible recommendation that no further corrective action is necessary. If it is determined that complete clean closure cannot be accomplished during the SAFER, then a hold point will have been reached and the Nevada Division of Environmental Protection (NDEP) will be consulted to determine whether the remaining contamination will be closed under the alternative corrective action of closure in place with use restrictions. This will be presented in a closure report that will be prepared and submitted to the NDEP for review and approval. The sites will be investigated based on the data quality objectives (DQOs) developed on December 14, 2009, by representatives of U.S.Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office; Navarro Nevada Environmental Services, LLC (NNES); and National Security Technologies

  18. Citizen's actions

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The role played by individual citizens as consumers of energy was examined, with emphasis on studying ways in which their action could result in energy conservation. It was shown that there are ways that energy can be conserved in this way, with citizens acting either individually or in groups. The potential savings are significant, but the actual savings may be quite small. The citizens need to be motivated to save and to believe in a conservation ethic; developing such an ethic is difficult, and perhaps not responsive to the shotgun approach now being attempted. The true course of action may be to synthesize new societal structures that provide the maximum evolution of culture within the limitation of scarce energy resources.

  19. [Femicide Across Europe COST Action, a transnational cooperation network for the study of and approach to femicide in Europe].

    PubMed

    Sanz-Barbero, Belén; Otero-García, Laura; Boira, Santiago; Marcuello, Chaime; Vives Cases, Carmen

    2016-01-01

    Femicide or the murder of women because of their gender is a recognised public health problem as well as a serious violation of human rights. Its magnitude worldwide is still unknown, given the methodological difficulties to differentiate these murders from other female homicides. The European Union programme entitled «European Cooperation in Science and Technology» (COST) launched the «Femicide across Europe» COST Action in 2013, establishing an optimal European framework for transnational cooperation among experts addressing great social and public health challenges such as femicide. This field note describes the main objectives, the participating groups of experts and the mid-term results of this experience.

  20. Examining barriers and supports to community living and participation after a stroke from a participatory action research approach.

    PubMed

    Hammel, Joy; Jones, Robin; Gossett, Andrea; Morgan, Elizabeth

    2006-01-01

    This participatory action research study focused on identifying community participation goals, barriers, and supports/strategies in partnership with people who have experienced a stroke. Goals demonstrate that participation is more than activity performance in context; instead, it relates to "being a part of" the community and having access to participation opportunities and supports. Results of community site audits from the first 20 participants document environmental (physical, cognitive, social) and system level barriers, as well as effective strategies for promoting participation via environmental modification and systems level changes. A consumer-directed, Web-based tool for documenting participation barriers and sharing strategies is discussed.

  1. A Network Pharmacology Approach to Understanding the Mechanisms of Action of Traditional Medicine: Bushenhuoxue Formula for Treatment of Chronic Kidney Disease

    PubMed Central

    Zheng, Xiao-yong; Cao, Dong-sheng; Ye, Fa-qing; Xiang, Zheng

    2014-01-01

    Traditional Chinese medicine (TCM) has unique therapeutic effects for complex chronic diseases. However, for the lack of an effective systematic approach, the research progress on the effective substances and pharmacological mechanism of action has been very slow. In this paper, by incorporating network biology, bioinformatics and chemoinformatics methods, an integrated approach was proposed to systematically investigate and explain the pharmacological mechanism of action and effective substances of TCM. This approach includes the following main steps: First, based on the known drug targets, network biology was used to screen out putative drug targets; Second, the molecular docking method was used to calculate whether the molecules from TCM and drug targets related to chronic kidney diseases (CKD) interact or not; Third, according to the result of molecular docking, natural product-target network, main component-target network and compound-target network were constructed; Finally, through analysis of network characteristics and literature mining, potential effective multi-components and their synergistic mechanism were putatively identified and uncovered. Bu-shen-Huo-xue formula (BSHX) which was frequently used for treating CKD, was used as the case to demonstrate reliability of our proposed approach. The results show that BSHX has the therapeutic effect by using multi-channel network regulation, such as regulating the coagulation and fibrinolytic balance, and the expression of inflammatory factors, inhibiting abnormal ECM accumulation. Tanshinone IIA, rhein, curcumin, calycosin and quercetin may be potential effective ingredients of BSHX. This research shows that the integration approach can be an effective means for discovering active substances and revealing their pharmacological mechanisms of TCM. PMID:24598793

  2. A participatory action research approach for identifying health service needs of Hispanic immigrants: implications for occupational therapy.

    PubMed

    Suarez-Balcazar, Yolanda; Martinez, Louise I; Casas-Byots, Clemencia

    2005-01-01

    SUMMARY Recently, the field of Community Occupational Therapy has started to enter into new research areas, one being participatory research. This paper illustrates a participatory research methodology adapted by community residents and a research team to identify the service needs of an underserved Hispanic population as well as set action agendas to meet their needs. In order to plan and implement health programs, community residents participated actively in the needs assessment, action agenda development and brainstorming of solutions to address health and community needs and concerns. Concerns identified included the lack of affordable bilingual dentists and youth involvement in gangs, drugs, and alcohol. The results of the needs assessment were shared and discussed during five public forums in which 180 Hispanics from the community discussed the dimensions of the issues and alternative solutions. This process resulted in an agenda of health issues and ideas for improvement from the perspective of Hispanics. We emphasized the advantages of using participatory methodologies when developing health and community services within Hispanic communities. Additionally, the implications for advancing a Scholarship of Practice agenda for Community Occupational Therapy are discussed.

  3. Prevention and public health approaches to trauma and traumatic stress: a rationale and a call to action

    PubMed Central

    Magruder, Kathryn M.; Kassam-Adams, Nancy; Thoresen, Siri; Olff, Miranda

    2016-01-01

    Background The field of trauma and traumatic stress is dominated by studies on treatments for those who experience adversity from traumatic experiences. While this is important, we should not neglect the opportunity to consider trauma in a public health perspective. Such a perspective will help to develop prevention approaches as well as extend the reach of early interventions and treatments. The purpose of this paper is to provide an introduction to a public health approach to trauma and traumatic stress and identify key opportunities for trauma professionals and our professional societies (such as the International Society for Traumatic Stress Studies [ISTSS] and the European Society for Traumatic Stress Studies [ESTSS]) to increase our societal impact by adopting such an approach. Method This paper reviews and summarizes key findings related to the public health impact of trauma. The special case of children is explored, and a case example of the Norwegian terrorist attacks in 2011 illustrates the potential for improving our response to community level traumatic events. We also discuss how professional organizations such as ESTSS and ISTSS, as well as individual trauma professionals, can and should play an important role in promoting a public health approach. Results Trauma is pervasive throughout the world and has negative impacts at the personal, family, community, and societal levels. A public health perspective may help to develop prevention approaches at all of these levels, as well as extend the reach of early interventions and treatments. Conclusions Professional organizations such as ESTSS and ISTSS can and should play an important role in promoting a public health approach. They should promote the inclusion of trauma in the global public health agenda and include public health in their activities. PMID:26996536

  4. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 415: Project 57 No. 1 Plutonium Dispersion (NTTR), Nevada, Revision 0

    SciTech Connect

    Matthews, Patrick; Burmeister, Mark

    2014-04-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 415, Project 57 No. 1 Plutonium Dispersion (NTTR). CAU 415 is located on Range 4808A of the Nevada Test and Training Range (NTTR) and consists of one corrective action site: NAFR-23-02, Pu Contaminated Soil. The CAU 415 site consists of the atmospheric release of radiological contaminants to surface soil from the Project 57 safety experiment conducted in 1957. The safety experiment released plutonium (Pu), uranium (U), and americium (Am) to the surface soil over an area of approximately 1.9 square miles. This area is currently fenced and posted as a radiological contamination area. Vehicles and debris contaminated by the experiment were subsequently buried in a disposal trench within the surface-contaminated, fenced area and are assumed to have released radiological contamination to subsurface soils. Potential source materials in the form of pole-mounted electrical transformers were also identified at the site and will be removed as part of closure activities.

  5. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 425: Area 9 Main Lake Construction Debris Disposal Area, Tonopah Test Range, Nevada

    SciTech Connect

    K. B. Campbell

    2002-04-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 425, Area 9 Main Lake Construction Debris Disposal Area. This CAU is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO, 1996). This site will be cleaned up under the SAFER process since the volume of waste exceeds the 23 cubic meters (m{sup 3}) (30 cubic yards [yd{sup 3}]) limit established for housekeeping sites. CAU 425 is located on the Tonopah Test Range (TTR) and consists of one Corrective Action Site (CAS) 09-08-001-TA09, Construction Debris Disposal Area (Figure 1). CAS 09-08-001-TA09 is an area that was used to collect debris from various projects in and around Area 9. The site is located approximately 81 meters (m) (265 feet [ft]) north of Edwards Freeway northeast of Main Lake on the TTR. The site is composed of concrete slabs with metal infrastructure, metal rebar, wooden telephone poles, and concrete rubble from the Hard Target and early Tornado Rocket sled tests. Other items such as wood scraps, plastic pipes, soil, and miscellaneous nonhazardous items have also been identified in the debris pile. It is estimated that this site contains approximately 2280 m{sup 3} (3000 yd{sup 3}) of construction-related debris.

  6. Hydrogen/Deuterium Exchange-LC-MS Approach to Characterize the Action of Heparan Sulfate C5-Epimerase

    PubMed Central

    Babu, Ponnusamy; Victor, Xylophone V.; Nelsen, Emily; Nguyen, Thao Kim Nu; Raman, Karthik; Kuberan, Balagurunathan

    2011-01-01

    Heparan sulfate (HS) proteoglycans regulate a number of biological functions in many systems. Most of the functions of HS are attributed to its unique structure, consisting of sulfated and non-sulfated domains, arising from the differential presence of iduronyl and glucuronyl residues along the polysaccharide chain. A single glucuronyl C5-epimerase enzyme acts on heparan sulfate precursor, converts glucuronyl residues into iduronyl residues and modulates subsequent biosynthetic steps in vivo. The ratios of non-sulfated epimers within the polysaccharide chain have been calculated by resolving radiolabeled GlcA-AManR and IdoA-AManR disaccharides using a tedious paper chromatography technique. Radioactive assay, based on measuring either the release or incorporation of 3H at C5 carbon of uronyl residues of 3H-labeled HS precursor substrate, has been in use over three decades to characterize the action of HS C5-epimerase. We have developed a non-radioactive assay to estimate the epimerase activity through resolving GlcA-AManR and IdoA-AManR disaccharides on HPLC in conjunction with hydrogen/deuterium exchange upon epimerization protocol-liquid chromatography mass spectrometry (DEEP-LC-MS). Utilizing this new, non-radioactive based assay, DEEP-LC-MS, we were able to determine the extent of both forward and reverse reaction on the same substrate catalyzed by C5-epimerase. Results from this study also provide insights into the action of C5-epimerase and provide an opportunity to delineate snapshots of biosynthetic events that occur during the HSPG assembly in the Golgi. PMID:21573838

  7. Human ergology that promotes participatory approach to improving safety, health and working conditions at grassroots workplaces: achievements and actions.

    PubMed

    Kawakami, Tsuyoshi

    2011-12-01

    Participatory approaches are increasingly applied to improve safety, health and working conditions of grassroots workplaces in Asia. The core concepts and methods in human ergology research such as promoting real work life studies, relying on positive efforts of local people (daily life-technology), promoting active participation of local people to identify practical solutions, and learning from local human networks to reach grassroots workplaces, have provided useful viewpoints to devise such participatory training programmes. This study was aimed to study and analyze how human ergology approaches were applied in the actual development and application of three typical participatory training programmes: WISH (Work Improvement for Safe Home) with home workers in Cambodia, WISCON (Work Improvement in Small Construction Sites) with construction workers in Thailand, and WARM (Work Adjustment for Recycling and Managing Waste) with waste collectors in Fiji. The results revealed that all the three programmes, in the course of their developments, commonly applied direct observation methods of the work of target workers before devising the training programmes, learned from existing local good examples and efforts, and emphasized local human networks for cooperation. These methods and approaches were repeatedly applied in grassroots workplaces by taking advantage of their the sustainability and impacts. It was concluded that human ergology approaches largely contributed to the developments and expansion of participatory training programmes and could continue to support the self-help initiatives of local people for promoting human-centred work.

  8. Professional Learning in Action: An Inquiry Approach for Teachers of Literacy. Common Core State Standards in Literacy Series

    ERIC Educational Resources Information Center

    Riski, Victoria J.; Vogt, Mary Ellen

    2016-01-01

    Risko and Vogt provide a unique and progressive approach for engaging the professional learning of teachers of literacy, reading specialists, literacy coaches and instructional leaders, content specialists, and administrators. Their deliberate use of Professional Learning signals the importance of educators engaging in authentic and inquiry-based…

  9. Addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 452: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Grant Evenson

    2009-05-01

    This document constitutes an addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 452: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, April 1998 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • The cover, title, and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the URs for CASs: • 25-25-09, Spill H940825C (from UST 25-3101-1) • 25-25-14, Spill H940314E (from UST 25-3102-3) • 25-25-15, Spill H941020E (from UST 25-3152-1) These URs were established as part of Federal Facility Agreement and Consent Order (FFACO) corrective actions and were based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since these URs were established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, these URs were re-evaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the URs) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove these URs because contamination is not present at these sites above the risk-based FALs

  10. Addendum 2 to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Grant Evenson

    2009-05-01

    This document constitutes an addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, April 1998 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • The cover, title, and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the URs for CASs: • 12-25-08, Spill H950524F (from UST 12-B-1) • 12-25-10, Spill H950919A (from UST 12-COMM-1) These URs were established as part of Federal Facility Agreement and Consent Order (FFACO) corrective actions and were based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since these URs were established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, these URs were re-evaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the URs) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove these URs because contamination is not present at these sites above the risk-based FALs. Requirements for inspecting and maintaining these URs will be

  11. Addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Undrground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Lynn Kidman

    2008-10-01

    This document constitutes an addendum to the April 1998, Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites as described in the document Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order (UR Modification document) dated February 2008. The UR Modification document was approved by NDEP on February 26, 2008. The approval of the UR Modification document constituted approval of each of the recommended UR modifications. In conformance with the UR Modification document, this addendum consists of: • This cover page that refers the reader to the UR Modification document for additional information • The cover and signature pages of the UR Modification document • The NDEP approval letter • The corresponding section of the UR Modification document This addendum provides the documentation justifying the cancellation of the UR for CAS 12-25-09, Spill 960722-02 (from UST 12-B-3). This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996; as amended August 2006). Since this UR was established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, this UR was re-evaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). This re-evaluation consisted of comparing the original data (used to define the need for the UR) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a

  12. Developing and evaluating interventions that are applicable and relevant to inpatients and those who care for them; a multiphase, pragmatic action research approach

    PubMed Central

    2014-01-01

    Background Randomised controlled trials may be of limited use to evaluate the multidisciplinary and multimodal interventions required to effectively treat complex patients in routine clinical practice; pragmatic action research approaches may provide a suitable alternative. Methods A multiphase, pragmatic, action research based approach was developed to identify and overcome barriers to nutritional care in patients admitted to a metropolitan hospital hip-fracture unit. Results Four sequential action research cycles built upon baseline data including 614 acute hip-fracture inpatients and 30 purposefully sampled clinicians. Reports from Phase I identified barriers to nutrition screening and assessment. Phase II reported post-fracture protein-energy intakes and intake barriers. Phase III built on earlier results; an explanatory mixed-methods study expanded and explored additional barriers and facilitators to nutritional care. Subsequent changes to routine clinical practice were developed and implemented by the treating team between Phase III and IV. These were implemented as a new multidisciplinary, multimodal nutritional model of care. A quasi-experimental controlled, ‘before-and-after’ study was then used to compare the new model of care with an individualised nutritional care model. Engagement of the multidisciplinary team in a multiphase, pragmatic action research intervention doubled energy and protein intakes, tripled return home discharge rates, and effected a 75% reduction in nutritional deterioration during admission in a reflective cohort of hip-fracture inpatients. Conclusions This approach allowed research to be conducted as part of routine clinical practice, captured a more representative patient cohort than previously reported studies, and facilitated exploration of barriers and engagement of the multidisciplinary healthcare workers to identify and implement practical solutions. This study demonstrates substantially different findings to those

  13. Application of Fixed Scale Approach to Static Quark Free Energies in Quenched and 2+1 Flavor Lattice QCD with Improved Wilson Quark Action

    NASA Astrophysics Data System (ADS)

    Maezawa, Y.; Umeda, T.; Aoki, S.; Ejiri, S.; Hatsuda, T.; Kanaya, K.; Ohno, H.; WHOT-QCD Collaboration

    2012-11-01

    The free energies of static quarks and the Debye screening masses in the quark gluon plasma are studied using Polyakov-line correlation functions in lattice QCD adopting the fixed-scale approach in which temperature is varied without changing the spatial volume and the renormalization factors. We calculate static-quark free energies in various color channels in the high temperature phase up to about 3.5 times the (pseudo-)critical temperature, performing lattice simulations both in quenched and 2 + 1 flavor QCD. For the quenched simulations, we adopt the plaquette gauge action on anisotropic 20^3 × N_t lattices with N_t = 8-26 at the renormalized anisotropy a_s / a_t ≃ 4. For 2 + 1 flavor QCD, we adopt the renormalization-group improved Iwasaki gluon action and the non-perturbatively O(a)-improved Wilson quark action on isotropic 32^3 × N_t lattices with N_t = 4-12 at m_{PS}/m_{V} = 0.63 (0.74) for the light (strange) flavors. We find that the color-singlet free energies at high temperatures converge to the zero-temperature static-quark potential evaluated from the Wilson-loop at short distances. This is in accordance with the theoretical expectation that the short distance physics is insensitive to the temperature. At long distances, the free energies approach twice the single-quark free energies, implying that the interaction between static quarks is fully screened. We find that the static-quark free energies for various color channels turn out to be well described by the screened Coulomb form, and the color-channel dependence of the inter-quark interaction can be described by the kinetic Casimir factor inspired from the lowest order perturbation theory. We also discuss comparison with a prediction of the thermal perturbation theory and flavor dependence of the screening masses.

  14. Streamlined Approach for Environmental Restoration Work Plan for Corrective Action Unit 329: Area 22 Desert Rock Airstrip Fuel Spill, Nevada Test Site, Nevada, Draft of Rev. 0

    SciTech Connect

    U.S. Department of Energy, Nevada Operations Office

    1999-09-28

    This plan was prepared as a characterization and closure report for Corrective Action Unit (CAU) 329: Area 22, Desert Rock Airstrip (DRA) Fuel Spill identified in the Federal Facility Agreement and Consent Order (FFACO). The CAU, located on the Nevada Test Site, consists of one Corrective Action Site (CAS), 22-44-01, which encompasses an area contaminated by three recorded spills from a 25,000-gallon underground fuel storage tank. The tank was installed in 1980 and was imbedded in sand and gravel approximately 16 feet below the ground surface. Historically, the DRA consisted of a single runway, several portable buildings, two underground storage tanks containing aviation jet fuel, and plumbing to several refueling areas on the ramp. The constituents of potential concern from the spill were total petroleum hydrocarbons as gasoline or JP-4. This provides the methodology for sampling contaminated soil-vapor and soil to determine what activities, if any, are required for closure of this si te. In addition, there is sufficient process knowledge of the tank's historical use to recommend closure of CAU 329 using the Streamlined Approach for Environmental Restoration (SAFER) process. This process combines elements of the Data Quality Objectives process and the observational approach to help plan and conduct corrective actions. The study concluded that the spill is localized; therefore, it is very unlikely that the underground water supply has been or will be affected by these spills. In addition, there were high levels of carbon dioxide detected above the release which indicate that the spill is currently in the process of undergoing biological degradation and is not migrating. This CAU has been approved by the Nevada Division of Environmental Protection (NDEP) to be moved into Appendix III of the FFACO. Closure is expected to be in-place with administrative controls and soil-vapor sampling. A closure report will be prepared and submitted to NDEP for review and approval

  15. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 177: Mud Pits and Cellars, Nevada Test Site, Nevada, Rev. No.: 0

    SciTech Connect

    Alfred Wickline

    2006-06-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for Corrective Action Unit (CAU) 177, Mud Pits and Cellars, identified in the ''Federal Facility Agreement and Consent Order''. Corrective Action Unit 177 consists of the 12 following Corrective Action Sites (CASs) located in Areas 8, 9, 19, and 20 of the Nevada Test Site: (1) 08-23-01, Mud Pit and Cellar; (2) 09-09-41, Unknown No.3 Mud Pit/Disposal Area; (3) 09-09-45, U-9bz PS No.1A Mud Pit (1) and Cellar; (4) 09-23-05, Mud Pit and Cellar; (5) 09-23-08, Mud Pit and Cellar; (6) 09-23-09, U-9itsx20 PS No.1A Cellar; (7) 10-23-02, Mud Pit and Cellar; (8) 10-23-03, Mud Pit and Cellar; (9) 19-23-01, Mud Pit and Cellar; (10) 19-23-02, Cellar and Waste Storage Area; (11) 19-23-03, Cellar with Casing; and (12) 20-23-07, Cellar. This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 177 using the SAFER process. The data quality objective process developed for this CAU identified the following expected closure options: (1) investigation and confirmation that no contamination exists above the preliminary action levels (PALs), leading to a no further action declaration, or (2) characterization of the nature and extent of contamination, leading to closure in place with use restrictions. The expected closure options were selected based on available information including contaminants of potential concern, future land use, and assumed risks. A decision flow process was developed to outline the collection of data necessary to achieve closure. There are two decisions that need to be answered for closure. Decision I is to determine whether contaminants of potential concern are present in concentrations exceeding the PALs

  16. Insights and participatory actions driven by a socio-hydrogeological approach for groundwater management: the Grombalia Basin case study (Tunisia)

    NASA Astrophysics Data System (ADS)

    Tringali, C.; Re, V.; Siciliano, G.; Chkir, N.; Tuci, C.; Zouari, K.

    2017-02-01

    Sustainable groundwater management strategies in water-scarce countries need to guide future decision-making processes pragmatically, by simultaneously considering local needs, environmental problems and economic development. The socio-hydrogeological approach named `Bir Al-Nas' has been tested in the Grombalia region (Cap Bon Peninsula, Tunisia), to evaluate the effectiveness of complementing hydrogeochemical and hydrogeological investigations with the social dimension of the issue at stake (which, in this case, is the identification of groundwater pollution sources). Within this approach, the social appraisal, performed through social network analysis and public engagement of water end-users, allowed hydrogeologists to get acquainted with the institutional dimension of local groundwater management, identifying issues, potential gaps (such as weak knowledge transfer among concerned stakeholders), and the key actors likely to support the implementation of the new science-based management practices resulting from the ongoing hydrogeological investigation. Results, hence, go beyond the specific relevance for the Grombaila basin, showing the effectiveness of the proposed approach and the importance of including social assessment in any given hydrogeological research aimed at supporting local development through groundwater protection measures.

  17. Dual-action Hybrid Compounds - A New Dawn in the Discovery of Multi-target Drugs: Lead Generation Approaches.

    PubMed

    Abdolmalekia, Azizeh; Ghasemi, Jahan B

    2016-09-27

    Finding high quality beginning compounds is a critical job at the start of the lead generation stage for multi-target drug discovery (MTDD). Designing hybrid compounds as a selective multi-target chemical entity is a challenge, opportunity, and new idea to better act against specific multiple targets. One hybrid molecule is formed by two (or more) pharmacophore group's participation. So, these new compounds often exhibit two or more activities going about as multi-target drugs (mt-drugs) and may have superior safety or efficacy. Application of integrating a range of information and sophisticated new in silico, bioinformatics, structural biology, pharmacogenomics methods may be useful to discover/design, and synthesis of the new hybrid molecules. In this regard, many rational and screening approaches have followed by medicinal chemists for the lead generation in MTDD. Here, we review some popular lead generation approaches that have been used for designing multiple ligands (DMLs). This paper focuses on dual- acting chemical entities that incorporate a part of two drugs or bioactive compounds to compose hybrid molecules. Also, it presents some of key concepts and limitations/strengths of lead generation methods by comparing combination framework method with screening approaches. Besides, a number of examples to represent applications of hybrid molecules in the drug discovery are included.

  18. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 465: Hydronuclear Nevada National Security Site, Nevada, with ROTC 1, Revision 0

    SciTech Connect

    Patrick Matthews

    2011-11-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 465, Hydronuclear, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 465 comprises the following four corrective action sites (CASs) located in Areas 6 and 27 of the Nevada National Security Site: (1) 00-23-01, Hydronuclear Experiment; (2) 00-23-02, Hydronuclear Experiment; (3) 00-23-03, Hydronuclear Experiment; (4) 06-99-01, Hydronuclear. The sites will be investigated based on the data quality objectives (DQOs) developed on July 6, 2011, by representatives of the Nevada Division of Environmental Protection (NDEP) and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for each CAS in CAU 465. For CAU 465, two potential release components have been identified. The subsurface release component includes potential releases of radiological and nonradiological contaminants from the subsurface hydronuclear experiments and disposal boreholes. The surface release component consists of other potential releases of radiological and nonradiological contaminants to surface soils that may have occurred during the pre- and post-test activities. This plan provides the methodology for collection of the necessary information for closing each CAS component. There is sufficient information and process knowledge from historical documentation, contaminant characteristics, existing regional and site groundwater models, and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 465 using the SAFER process. For potential subsurface releases, flow and transport models will be developed to integrate existing data into a conservative

  19. Evaluation of nystatin containing chitosan hydrogels as potential dual action bio-active restorative materials: in vitro approach.

    PubMed

    Perchyonok, V Tamara; Reher, Vanessa; Zhang, Shengmiao; Basson, Nicki; Grobler, Sias

    2014-11-28

    Healing is a specific biological process related to the general phenomenon of growth and tissue regeneration and is a process generally affected by several systemic conditions or as detrimental side-effects of chemotherapy- and radiotherapy-induced inflammation of the oral mucosa. The objectives of this study is to evaluate the novel chitosan based functional drug delivery systems, which can be successfully incorporated into "dual action bioactive restorative materials", capable of inducing in vitro improved wound healing prototype and containing an antibiotic, such as nystatin, krill oil as an antioxidant and hydroxyapatite as a molecular bone scaffold, which is naturally present in bone and is reported to be successfully used in promoting bone integration when implanted as well as promoting healing. The hydrogels were prepared using a protocol as previously reported by us. The physico-chemical features, including surface morphology (SEM), release behaviors, stability of the therapeutic agent-antioxidant-chitosan, were measured and compared to the earlier reported chitosan-antioxidant containing hydrogels. Structural investigations of the reactive surface of the hydrogel are reported. Release of nystatin was investigated for all newly prepared hydrogels. Bio-adhesive studies were performed in order to assess the suitability of these designer materials. Free radical defense capacity of the biomaterials was evaluated using established in vitro model. The bio-adhesive capacity of the materials in the in vitro system was tested and quantified. It was found that the favorable synergistic effect of free radical built-in defense mechanism of the new functional materials increased sustainable bio-adhesion and therefore acted as a functional multi-dimensional restorative material with potential application in wound healing in vitro.

  20. Turning scientific approaches into practical conservation actions: the case of Comunidad Indigena de Nuevo San Juan Parangaricutiro, Mexico.

    PubMed

    Velázquez, A; Bocco, G; Torres, A

    2001-05-01

    Optimum natural resource management and biodiversity conservation are desirable goals. These, however, often exclude each other, since maximum economic benefits have promoted drastic reductions in biodiversity throughout the world. This dilemma confronts local stakeholders, who usually go for maximizing economic inputs, whereas other social (e.g., academic) sectors are favor conservation practices. In this paper we describe the way two scientific approaches--landscape and participatory research--were used to develop sound and durable land use scenarios. These two approaches included expert knowledge of both social and environmental conditions in indigenous communities. Our major emphasis was given to detect spatially explicit land use scenarios and capacity building in order to construct a decision support system operated by stakeholders of the Comunidad Indigena de Nuevo San Juan Parangaricutiro in Mexico. The system for decision-making was fed with data from inventories of both abiotic and biotic biodiversity components. All research, implementation, and monitoring activities were conducted in close collaboration with members of the indigenous community. As a major result we obtained a number of forest alternative uses that favor emerging markets and make this indigenous community less dependent on a single market. Furthermore, skilled members of the community are now running the automated system for decision-making. In conclusion, our results were better expressed as products with direct benefits in local livelihoods rather than pure academic outputs.

  1. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 544: Cellars, Mud Pits, and Oil Spills, Nevada Test Site, Nevada, Revision 0

    SciTech Connect

    Mark Krauss

    2010-07-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions needed to achieve closure for Corrective Action Unit (CAU) 544, Cellars, Mud Pits, and Oil Spills, identified in the Federal Facility Agreement and Consent Order (FFACO). Corrective Action Unit 544 comprises the following 20 corrective action sites (CASs) located in Areas 2, 7, 9, 10, 12, 19, and 20 of the Nevada Test Site (NTS): • 02-37-08, Cellar & Mud Pit • 02-37-09, Cellar & Mud Pit • 07-09-01, Mud Pit • 09-09-46, U-9itsx20 PS #1A Mud Pit • 10-09-01, Mud Pit • 12-09-03, Mud Pit • 19-09-01, Mud Pits (2) • 19-09-03, Mud Pit • 19-09-04, Mud Pit • 19-25-01, Oil Spill • 19-99-06, Waste Spill • 20-09-01, Mud Pits (2) • 20-09-02, Mud Pit • 20-09-03, Mud Pit • 20-09-04, Mud Pits (2) • 20-09-06, Mud Pit • 20-09-07, Mud Pit • 20-09-10, Mud Pit • 20-25-04, Oil Spills • 20-25-05, Oil Spills This plan provides the methodology for field activities needed to gather the necessary information for closing each CAS. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of CAU 544 using the SAFER process. Using the approach approved for previous mud pit investigations (CAUs 530–535), 14 mud pits have been identified that • are either a single mud pit or a system of mud pits, • are not located in a radiologically posted area, and • have no evident biasing factors based on visual inspections. These 14 mud pits are recommended for no further action (NFA), and further field investigations will not be conducted. For the sites that do not meet the previously approved closure criteria, additional information will be obtained by conducting a field investigation before selecting the appropriate corrective action for each CAS. The results of the field investigation will support a defensible

  2. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 330: Areas 6, 22, and 23 Tanks and Spill Sites, Nevada Test Site, Nevada

    SciTech Connect

    T. M. Fitzmaurice

    2001-08-01

    This Streamlined Approach for Environmental restoration (SAFER) plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 330, Areas 6,22, and 23 Tanks and Spill Sites. The CAUs are currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO). This CAU is located at the Nevada Test Site (NTS) (Figure 1). CAU 330 consists of the following Corrective Action Sites (CASs): (1) CAS 06-02-04 - Consists of an underground tank and piping. This CAS is close to an area that was part of the Animal Investigation Program (AIP), conducted under the U.S. Public Health Service. Its purpose was to study and perform tests on the cattle and wild animals in and around the NTS that were exposed to radionuclides. It is unknown if this tank was part of these operations. (2) CAS 22-99-06 - Is a fuel spill that is believed to be a waste oil release which occurred when Camp Desert Rock was an active facility. This CAS was originally identified as being a small depression where liquids were poured onto the ground, located on the west side of Building T-1001. This building has been identified as housing a fire station, radio station, and radio net remote and telephone switchboard. (3) CAS 23-01-02 - Is a large aboveground storage tank (AST) farm that was constructed to provide gasoline and diesel storage in Area 23. The site consists of two ASTs, a concrete foundation, a surrounding earthen berm, associated piping, and unloading stations. (4) CAS 23-25-05 - Consists of an asphalt oil spill/tar release that contains a wash covered with asphalt oil/tar material, a half buried 208-liter (L) (55-gallon [gal]) drum, rebar, and concrete located in the vicinity.

  3. Validation and psychometric evaluation of physical activity belief scale among patients with type 2 diabetes mellitus: an application of health action process approach

    PubMed Central

    Rohani, Hosein; Eslami, Ahmad Ali; Ghaderi, Arsalan; Jafari-Koshki, Tohid; Sadeghi, Erfan; Bidkhori, Mohammad; Raei, Mehdi

    2016-01-01

    Background: Moderate increase in physical activity (PA) may be helpful in preventing or postponing the complications of type 2 diabetes mellitus (T2DM). The aim of this study was to assess the psychometric properties of a health action process approach (HAPA)-based PA inventory among T2DM patients. Methods: In 2015, this cross-sectional study was carried out on 203 participants recruited by convenience sampling in Isfahan, Iran. Content and face validity was confirmed by a panel of experts. The comments noted by 9 outpatients on the inventory were also investigated. Then,the items were administered to 203 T2DM patients. Construct validity was conducted using exploratory and structural equation modeling confirmatory factor analyses. Reliability was also assessed with Cronbach alpha and interclass correlation coefficient (ICC). Results: Content validity was acceptable (CVR = 0.62, CVI = 0.89). Exploratory factor analysis extracted seven factors (risk- perception, action self-efficacy, outcome expectancies, maintenance self-efficacy, action and coping planning, behavioral intention, and recovery self-efficacy) explaining 82.23% of the variation. The HAPA had an acceptable fit to the observations (χ2 = 3.21, df = 3, P = 0.38; RMSEA = 0.06; AGFI = 0.90; PGFI = 0.12). The range of Cronbach alpha and ICC for the scales was about 0.63 to 0.97 and 0.862 to 0.988, respectively. Conclusion: The findings of the present study provided an initial support for the reliability and validity of the HAPA-based PA inventory among patients with T2DM. PMID:27386421

  4. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 326: Areas 6 and 27 Release Sites, Nevada Test Site, Nevada

    SciTech Connect

    A. T. Urbon

    2001-09-01

    This Streamlined Approach for Environmental Restoration (SAFER) plan addresses the action necessary for the closure of Corrective Action Unit (CAU) 326, Areas 6 and 27 Release Sites. This CAU is currently listed in the January 2001, Appendix III of the Federal Facilities Agreement and Consent Order (FFACO) (FFACO, 1996). CAU 326 is located on the Nevada Test Site (NTS) and consists of the following four Corrective Action Sites (CASS) (Figure 1): CAS 06-25-01--Is a rupture in an underground pipe that carried heating oil (diesel) from the underground heating oil tank (Tank 6-CP-1) located to the west of Building CP-70 to the boiler in Building CP-1 in the Area 6 Control Point (CP) compound. CAS 06-25-02--A heating oil spill that is a result of overfilling an underground heating oil tank (Tank 6-DAF-5) located at the Area 6 Device Assembly Facility (DAF). CAS 06-25-04--A release of waste oil that occurred while removing used oil to from Tank 6-619-4. Tank 6-619-4 is located northwest of Building 6-619 at the Area 6 Gas Station. CAS 27-25-01--Consists of an excavation that was created in an attempt to remove impacted stained soil from the Site Maintenance Yard in Area 27. Approximately 53.5 cubic meters (m{sup 3}) (70 cubic yards [yd{sup 3}]) of soil impacted by total petroleum hydrocarbons (TPH) and polychlorinated biphenyls (PCBs) was excavated before the excavation activities were halted. The excavation activities were stopped because the volume of impacted soil exceeded estimated quantities and budget.

  5. The assessment and management of diabetes related lower limb problems in India-an action research approach to integrating best practice

    PubMed Central

    2014-01-01

    Background In this article the authors explore the current issues and barriers related to achieving successful outcomes to diabetic foot complications in India. This was achieved by engaging clinicians in taking ownership of the problems and facilitating them in the identification of solutions to action change in clinical practice. Methods This was accomplished through facilitating participants in this study via a process of problem identification and planning, the first phases of an action research cycle approach. The methods of data collection were focus groups, observations and individual conversations. The data were analysed using a thematic framework. Results Based on the practitioner’s experiences and opinions, key themes were identified. These themes had the potential to inform the changes needed in clinical practice, to overcome barriers and embed ownership of the solutions. Five themes were identified highlighting: concerns over a fragmented service; local recognition of need; lack of standardised care pathways; lack of structured assessment and an absence of annual foot screening. Combined, the issues identified were thought to be important in preventing timely assessment and management of foot problems. Conclusion It was unanimously agreed that a formalised process of foot assessment should be developed and implemented as part of the subsequent phases of the action research process, which the authors intended to take forward and report in a further paper. The aim of which is to guide triage, education, care pathways, audit and evaluation of outcomes. Facilitation of the clinicians in developing a program and screening tool to implement and teach these skills to others could be an important step in reducing the number of high-risk cases that are often resulting in the amputation of limbs. PMID:24862010

  6. Acción Mutua (Shared Action): a multipronged approach to delivering capacity-building assistance to agencies serving Latino communities in the United States.

    PubMed

    Ayala, George; Chión, Miguel; Díaz, Rafael M; Heckert, Andrea L; Nuño, Monica; del Pino, Homero E; Rodríguez, Claudia; Schroeder, Kurt; Smith, Terry

    2007-01-01

    Culturally appropriate, theory-based capacity-building assistance can serve a vital role in helping HIV prevention providers remain up-to-date, effective, and responsive to those they serve. Funded by the Centers for Disease Control and Prevention (CDC), AIDS Project Los Angeles, in collaboration with San Francisco State University's César E. Chávez Institute, conducted full-day site visits and qualitative interviews in 2005 with mid-level management staff of CDC-funded community-based organizations delivering HIV prevention services to Latino communities in the western region of the United States. We found that agencies we visited (1) had not yet adapted the evidence-based interventions they were using at the time of our visit and (2) requested technical assistance and training in the areas of program development, evaluation, group facilitation techniques, consumer recruitment, client retention, intervention adaptation, and materials development. Findings from this needs assessment were used to inform our seven-pronged approach to delivering capacity-building assistance entitled "Acción Mutua" (Shared Action). The approach emphasizes strategic partnerships, stakeholder involvement, organizational self-assessment, culturally appropriate materials development, interactive training, tailored onsite technical assistance, and professional networking opportunities. This article describes our approach in detail, the assessment process we used to develop it, and its implications for capacity-building practice.

  7. Dose-Response Analysis in the Joint Action of Two Effectors. A New Approach to Simulation, Identification and Modelling of Some Basic Interactions

    PubMed Central

    Murado García, Miguel Anxo; Prieto Lage, Miguel Ángel

    2013-01-01

    In systems with several effectors, the results of dose-response (DR) experiments are usually assessed by checking them against two hypotheses: independent action (IA) and concentration addition (CA). Both are useful simplifications, but do not represent the only possible responses, and avoid to a large extent the analysis of the interactions that are possible in the system. In addition, these are often applied in such a way that they produce insufficient descriptions of the problem that raises them, frequent inconclusive cases and doubtful decisions. In this work a generative approach is attempted, starting from some simple mechanisms necessarily underlying the response of an elementary biological entity to an effector agent. A set of simulations is formulated next through an equally simple system of logical rules, and several families of virtual responses are thus generated. These families include typical responses of IA and CA modes of action, other ones not less probable from a physiological point of view, and even other derived from common and expectable forms of interactions. The analysis of these responses enabled, firstly, to relate some phenomenological regularities with some general mechanistic principles, and to detect several causes by which the IA-CA dualism is necessarily ambiguous. Secondly, it allowed identifying different forms of synergy and antagonism that contribute to explain some controversial aspects of these notions. Finally, it led to propose two sets of explicit algebraic equations that describe accurately a wide diversity of possible and realistic responses. PMID:23637825

  8. Streamlined approach for environmental restoration work plan for Corrective Action Unit 126: Closure of aboveground storage tanks, Nevada Test Site, Nevada. Revision 1

    SciTech Connect

    1998-07-01

    This plan addresses the closure of several aboveground storage tanks in Area 25 of the Nevada Test Site. The unit is currently identified as Corrective Action Unit 126 in the Federal Facility Agreement and Consent Order and is listed as having six Corrective Action Sites. This plan addresses the Streamlined Approach for Environmental Restoration closure for five of the six sites. Four of the CASs are located at the Engine Test Stand complex and one is located in the Central Support Area. The sites consist of aboveground tanks, two of which were used to store diesel fuel and one stored Nalcool (an antifreeze mixture). The remaining tanks were used as part of a water demineralization process and stored either sulfuric acid or sodium hydroxide, and one was used as a charcoal adsorption furnace. Closure will be completed by removal of the associated piping, tank supports and tanks using a front end loader, backhoe, and/or crane. When possible, the tanks will be salvaged as scrap metal. The piping that is not removed will be sealed using a cement grout.

  9. Skin reactivity of unsensitized monkeys upon challenge with staphylococcal enterotoxin B: a new approach for investigating the site of toxin action.

    PubMed Central

    Scheuber, P H; Golecki, J R; Kickhöfen, B; Scheel, D; Beck, G; Hammer, D K

    1985-01-01

    The correlation between skin tests and emetic responses in unsensitized monkeys was used to elucidate the cellular site of action of staphylococcal enterotoxin B (SEB). Evidence is presented that SEB administered intradermally provoked immediate-type skin reactions associated with mild degranulation of cutaneous mast cells. The cytoplasma showed signs of synthetic and metabolic activity, with formation of vesicles and increased prominence of mitochondria. Carboxymethylation of histidine residues of SEB altered the molecule (cSEB) from more alkaline components to more acidic species with increased microheterogeneity. This modification caused a loss in toxicity and completely abrogated the skin-sensitizing activity without changing the immunological specificity. cSEB, however, could compete with SEB for binding sites on the target cell surface. Previously, compound 48/80-treated skin sites behaved refractively to challenge with SEB, indicating that mediators from cutaneous mast cells are required for SEB-induced skin reactions. Skin reactions as well as emetic responses challenged with SEB were completely inhibited by H2 receptor antagonists and calcium channel blockers but not by H1 antihistamine or competitive antagonists of serotonin. This new approach provides a model for investigating the mechanisms of SEB action. Images PMID:2866161

  10. A network pharmacology approach to discover active compounds and action mechanisms of San-Cao Granule for treatment of liver fibrosis

    PubMed Central

    Wei, Shizhang; Niu, Ming; Wang, Jian; Wang, Jiabo; Su, Haibin; Luo, Shengqiang; Zhang, Xiaomei; Guo, Yanlei; Liu, Liping; Liu, Fengqun; Zhao, Qingguo; Chen, Hongge; Xiao, Xiaohe; Zhao, Pan; Zhao, Yanling

    2016-01-01

    Ethnopharmacological relevance San-Cao Granule (SCG) has been used in patients with liver fibrosis for many years and has shown good effect. However, its mechanism of therapeutic action is not clear because of its complex chemical system. The purpose of our study is to establish a comprehensive and systemic method that can predict the mechanism of action of SCG in antihepatic fibrosis. Materials and methods In this study, a “compound–target–disease” network was constructed by combining the SCG-specific and liver fibrosis–specific target proteins with protein–protein interactions, and network pharmacology was used to screen out the underlying targets and mechanisms of SCG for treatment of liver fibrosis. Then, some key molecules of the enriched pathway were chosen to verify the effects of SCG on liver fibrosis induced by thioacetamide (TAA). Results This systematic approach had successfully revealed that 16 targets related to 11 SCG compounds were closely associated with liver fibrosis therapy. The pathway-enrichment analysis of them showed that the TGF-β1/Smad signaling pathway is relatively important. Animal experiments also proved that SCG could significantly ameliorate liver fibrosis by inhibiting the TGF-β1/Smad pathway. Conclusion SCG could alleviate liver fibrosis through the molecular mechanisms predicted by network pharmacology. Furthermore, network pharmacology could provide deep insight into the pharmacological mechanisms of Chinese herbal formulas. PMID:26929602

  11. Dose-response analysis in the joint action of two effectors. A new approach to simulation, identification and modelling of some basic interactions.

    PubMed

    Murado García, Miguel Anxo; Prieto Lage, Miguel Ángel

    2013-01-01

    In systems with several effectors, the results of dose-response (DR) experiments are usually assessed by checking them against two hypotheses: independent action (IA) and concentration addition (CA). Both are useful simplifications, but do not represent the only possible responses, and avoid to a large extent the analysis of the interactions that are possible in the system. In addition, these are often applied in such a way that they produce insufficient descriptions of the problem that raises them, frequent inconclusive cases and doubtful decisions. In this work a generative approach is attempted, starting from some simple mechanisms necessarily underlying the response of an elementary biological entity to an effector agent. A set of simulations is formulated next through an equally simple system of logical rules, and several families of virtual responses are thus generated. These families include typical responses of IA and CA modes of action, other ones not less probable from a physiological point of view, and even other derived from common and expectable forms of interactions. The analysis of these responses enabled, firstly, to relate some phenomenological regularities with some general mechanistic principles, and to detect several causes by which the IA-CA dualism is necessarily ambiguous. Secondly, it allowed identifying different forms of synergy and antagonism that contribute to explain some controversial aspects of these notions. Finally, it led to propose two sets of explicit algebraic equations that describe accurately a wide diversity of possible and realistic responses.

  12. Improving actions to control high blood pressure in Hispanic communities — Racial and Ethnic Approaches to Community Health Across the U.S. Project, 2009–2012☆

    PubMed Central

    Liao, Youlian; Siegel, Paul Z.; White, Shannon; Dulin, Rick; Taylor, April

    2015-01-01

    Background Compared with the general population in the United States (U.S.), Hispanics with hypertension are less likely to be aware of their condition, to take antihypertensive medication, and to adopt healthy lifestyles to control high blood pressure. We examined whether a multi-community intervention successfully increased the prevalence of actions to control hypertension among Hispanics. Methods Annual survey from 2009–2012 was conducted in six Hispanic communities in the Racial and Ethnic Approaches to Community Health (REACH) Across the U.S. project. The survey used address based sampling design that matched the geographies of intervention program. Results Age- and sex-standardized prevalences of taking hypertensive medication, changing eating habits, cutting down on salt, and reducing alcohol use significantly increased among Hispanics with self-reported hyper-tension in REACH communities. The 3-year relative percent increases were 5.8, 6.8, 7.9, and 35.2% for the four indicators, respectively. These favorable (healthier) trends occurred in both foreign-born and U.S.-born Hispanics. Conclusion This large community-based participatory intervention resulted in more Hispanic residents in the communities taking actions to control high blood pressure. PMID:26656406

  13. Modeling Approach/Strategy for Corrective Action Unit 99: Rainier Mesa and Shoshone Mountain, Nevada Test Site, Nye County, Nevada, Revision 1, with ROTC-1

    SciTech Connect

    Greg Ruskauff

    2008-06-01

    This document describes an approach for preliminary (Phase I) flow and transport modeling for the Rainier Mesa/Shoshone Mountain (RMSM) Corrective Action Unit (CAU). This modeling will take place before the planned Phase II round of data collection to better identify the remaining data gaps before the fieldwork begins. Because of the geologic complexity, limited number of borings, and large vertical gradients, there is considerable uncertainty in the conceptual model for flow; thus different conceptual models will be evaluated, in addition to different framework and recharge models. The transport simulations will not be used to formally calculate the Contaminant Boundary at this time. The modeling (Phase II) will occur only after the available data are considered sufficient in scope and quality.

  14. Algebraic geometry approach in gravity theory and new relations between the parameters in type I low-energy string theory action in theories with extra dimensions

    NASA Astrophysics Data System (ADS)

    Dimitrov, B. G.

    2010-02-01

    On the base of the distinction between covariant and contravariant metric tensor components, a new (multivariable) cubic algebraic equation for reparametrization invariance of the gravitational Lagrangian has been derived and parametrized with complicated non - elliptic functions, depending on the (elliptic) Weierstrass function and its derivative. This is different from standard algebraic geometry, where only two-dimensional cubic equations are parametrized with elliptic functions and not multivariable ones. Physical applications of the approach have been considered in reference to theories with extra dimensions. The s.c. "length function" l(x) has been introduced and found as a solution of quasilinear differential equations in partial derivatives for two different cases of "compactification + rescaling" and "rescaling + compactification". New physically important relations (inequalities) between the parameters in the action are established, which cannot be derived in the case $l=1$ of the standard gravitational theory, but should be fulfilled also for that case.

  15. Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action.

    PubMed

    Bedogni, Francesco; Rossi, Riccardo L; Galli, Francesco; Cobolli Gigli, Clementina; Gandaglia, Anna; Kilstrup-Nielsen, Charlotte; Landsberger, Nicoletta

    2014-10-01

    Rett syndrome (RTT) is a devastating genetic disorder that worldwide represents the most common genetic cause of severe intellectual disability in females. Most cases are caused by mutations in the X-linked MECP2 gene. Several recent studies have demonstrated that RTT mimicking animal models do not develop an irreversible condition and phenotypic rescue is possible. However, no cure for RTT has been identified so far, and patients are only given symptomatic and supportive treatments. The development of clinical applications imposes a more comprehensive knowledge of MeCP2 functional role(s) and their relevance for RTT pathobiology. Herein, we thoroughly survey the knowledge about MeCP2 structure and functions, highlighting the necessity of identifying more functional domains and the value of molecular genetics. Given that, in our opinion, RTT ultimately is generated by perturbations in gene transcription and so far no genes/pathways have been consistently linked to a dysfunctional MeCP2, we have used higher-level bioinformatic analyses to identify commonly deregulated mechanisms in MeCP2-defective samples. In this review we present our results and discuss the possible value of the utilized approach.

  16. Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach.

    PubMed

    Schürer, Gudrun; Lanig, Harald; Clark, Timothy

    2004-05-11

    The aminopeptidase of Aeromonas proteolytica (AAP) belongs to the group of metallo-hydrolases that require two divalent cations for full activity. Such binuclear metal centers are found in several aminopeptidases, raising the question whether a common mechanism, at least partly, is likely. We have used a quantum mechanical/molecular mechanical (QM/MM) approach to investigate the reaction mechanism of AAP. Among several possibilities, one reaction path was found to be clearly the most favorable. Beside the chemical transformation steps, effects of the enzyme environment and the influence of the solvent on the catalytic reaction were included in the study. The results are in good agreement with experimental studies and correspond to a high degree to our previous QM/MM calculations on the reaction mechanism of the related binuclear bovine lens leucine aminopeptidase (blLAP), which, although related to the AAP, has different Zn(2+)-coordination spheres and a different catalytic residue. The mechanisms of the two enzymes as suggested in the literature differ on the mode of coordination of the nucleophile and the identity of the general base. However, the results of this and our previous work on blLAP allow us to identify a common mechanism for the two enzymes. This mechanism is probably quite general for binuclear zinc enzymes.

  17. ACTION. 1977 Annual Report.

    ERIC Educational Resources Information Center

    ACTION, Washington, DC.

    In this report are described projects and activities undertaken by ACTION's volunteer programs in 1977. The first section concentrates on reviews conducted, including a major review of ACTION's domestic volunteer programs and the management systems supporting them and an assessment of its programs using the Zero-Base Budget approach called for by…

  18. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 356: Mud Pits and Disposal Sites, Nevada Test Site, Nevada (Revision No. 0, August 2001)

    SciTech Connect

    U.S. Department of Energy, National Nuclear Security Administration Nevada Operations Office

    2001-08-21

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses the actions necessary for the characterization and closure of Corrective Action Unit (CAU) 356, Mud Pits and Disposal Sites, as identified in the Federal Facility Agreement and Consent Order (FFACO). The CAU, located on the Nevada Test Site in Nevada, consists of seven Corrective Action Sites (CASs): CAS 03-04-01, Area 3 Change House Septic System; CAS 03-09-01, Mud Pit Spill Over; CAS 03-09-03, Mud Pit; CAS 03-09-04, Mud Pit; CAS 03-09-05, Mud Pit; CAS 20-16-01, Landfill; CAS 20-22-21, Drums. Sufficient information and process knowledge from historical documentation and investigations are the basis for the development of the phased approach chosen to address the data collection activities prior to implementing the preferred closure alternative for each CAS. The Phase I investigation will determine through collection of environmental samples from targeted populations (i.e., mud/soil cuttings above textural discontinuity) if contaminants of potential concern (COPCs) are present in concentrations exceeding preliminary action levels (PALs) at each of the CASs. If COPCs are present above PALs, a Phase II investigation will be implemented to determine the extent of contamination to support the appropriate corrective action alternative to complete closure of the site. Groundwater impacts from potentially migrating contaminants are not expected due to the depths to groundwater and limiting hydrologic drivers of low precipitation and high evaporation rates. Future land-use scenarios limit future uses to industrial activities; therefore, future residential uses are not considered. Potential exposure routes to site workers from contaminants of concern in septage and soils include oral ingestion, inhalation, or dermal contact (absorption) through in-advertent disturbance of contaminated structures and/or soils. Diesel within drilling muds is expected to be the primary COPC based on process

  19. Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

    PubMed Central

    Labib, Sarah; Bourdon-Lacombe, Julie; Kuo, Byron; Buick, Julie K.; Lemieux, France; Williams, Andrew; Halappanavar, Sabina; Malik, Amal; Luijten, Mirjam; Aubrecht, Jiri; Hyduke, Daniel R.; Fornace, Albert J.; Swartz, Carol D.; Recio, Leslie; Yauk, Carole L.

    2015-01-01

    Toxicogenomics is proposed to be a useful tool in human health risk assessment. However, a systematic comparison of traditional risk assessment approaches with those applying toxicogenomics has never been done. We conducted a case study to evaluate the utility of toxicogenomics in the risk assessment of benzo[a]pyrene (BaP), a well-studied carcinogen, for drinking water exposures. Our study was intended to compare methodologies, not to evaluate drinking water safety. We compared traditional (RA1), genomics-informed (RA2) and genomics-only (RA3) approaches. RA2 and RA3 applied toxicogenomics data from human cell cultures and mice exposed to BaP to determine if these data could provide insight into BaP's mode of action (MOA) and derive tissue-specific points of departure (POD). Our global gene expression analysis supported that BaP is genotoxic in mice and allowed the development of a detailed MOA. Toxicogenomics analysis in human lymphoblastoid TK6 cells demonstrated a high degree of consistency in perturbed pathways with animal tissues. Quantitatively, the PODs for traditional and transcriptional approaches were similar (liver 1.2 vs. 1.0 mg/kg-bw/day; lung 0.8 vs. 3.7 mg/kg-bw/day; forestomach 0.5 vs. 7.4 mg/kg-bw/day). RA3, which applied toxicogenomics in the absence of apical toxicology data, demonstrates that this approach provides useful information in data-poor situations. Overall, our study supports the use of toxicogenomics as a relatively fast and cost-effective tool for hazard identification, preliminary evaluation of potential carcinogens, and carcinogenic potency, in addition to identifying current limitations and practical questions for future work. PMID:25605026

  20. Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water.

    PubMed

    Moffat, Ivy; Chepelev, Nikolai L; Labib, Sarah; Bourdon-Lacombe, Julie; Kuo, Byron; Buick, Julie K; Lemieux, France; Williams, Andrew; Halappanavar, Sabina; Malik, Amal I; Luijten, Mirjam; Aubrecht, Jiri; Hyduke, Daniel R; Fornace, Albert J; Swartz, Carol D; Recio, Leslie; Yauk, Carole L

    2015-01-01

    Toxicogenomics is proposed to be a useful tool in human health risk assessment. However, a systematic comparison of traditional risk assessment approaches with those applying toxicogenomics has never been done. We conducted a case study to evaluate the utility of toxicogenomics in the risk assessment of benzo[a]pyrene (BaP), a well-studied carcinogen, for drinking water exposures. Our study was intended to compare methodologies, not to evaluate drinking water safety. We compared traditional (RA1), genomics-informed (RA2) and genomics-only (RA3) approaches. RA2 and RA3 applied toxicogenomics data from human cell cultures and mice exposed to BaP to determine if these data could provide insight into BaP's mode of action (MOA) and derive tissue-specific points of departure (POD). Our global gene expression analysis supported that BaP is genotoxic in mice and allowed the development of a detailed MOA. Toxicogenomics analysis in human lymphoblastoid TK6 cells demonstrated a high degree of consistency in perturbed pathways with animal tissues. Quantitatively, the PODs for traditional and transcriptional approaches were similar (liver 1.2 vs. 1.0 mg/kg-bw/day; lungs 0.8 vs. 3.7 mg/kg-bw/day; forestomach 0.5 vs. 7.4 mg/kg-bw/day). RA3, which applied toxicogenomics in the absence of apical toxicology data, demonstrates that this approach provides useful information in data-poor situations. Overall, our study supports the use of toxicogenomics as a relatively fast and cost-effective tool for hazard identification, preliminary evaluation of potential carcinogens, and carcinogenic potency, in addition to identifying current limitations and practical questions for future work.

  1. Choosing Actions

    PubMed Central

    Rosenbaum, David A.; Chapman, Kate M.; Coelho, Chase J.; Gong, Lanyun; Studenka, Breanna E.

    2013-01-01

    Actions that are chosen have properties that distinguish them from actions that are not. Of the nearly infinite possible actions that can achieve any given task, many of the unchosen actions are irrelevant, incorrect, or inappropriate. Others are relevant, correct, or appropriate but are disfavored for other reasons. Our research focuses on the question of what distinguishes actions that are chosen from actions that are possible but are not. We review studies that use simple preference methods to identify factors that contribute to action choices, especially for object-manipulation tasks. We can determine which factors are especially important through simple behavioral experiments. PMID:23761769

  2. Action semantics modulate action prediction.

    PubMed

    Springer, Anne; Prinz, Wolfgang

    2010-11-01

    Previous studies have demonstrated that action prediction involves an internal action simulation that runs time-locked to the real action. The present study replicates and extends these findings by indicating a real-time simulation process (Graf et al., 2007), which can be differentiated from a similarity-based evaluation of internal action representations. Moreover, results showed that action semantics modulate action prediction accuracy. The semantic effect was specified by the processing of action verbs and concrete nouns (Experiment 1) and, more specifically, by the dynamics described by action verbs (Experiment 2) and the speed described by the verbs (e.g., "to catch" vs. "to grasp" vs. "to stretch"; Experiment 3). These results propose a linkage between action simulation and action semantics as two yet unrelated domains, a view that coincides with a recent notion of a close link between motor processes and the understanding of action language.

  3. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 116: Area 25 Test Cell C Facility, Nevada Test Site, Nevada, Revision 1

    SciTech Connect

    NSTec Environmental Restoration

    2008-12-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan identifies the activities required for the closure of Corrective Action Unit (CAU) 116, Area 25 Test Cell C Facility. The Test Cell C (TCC) Facility is located in Area 25 of the Nevada Test Site (NTS) approximately 25 miles northwest of Mercury, Nevada (Figure 1). CAU 116 is currently listed in Appendix III of the Federal Facility Agreement and Consent Order (FFACO) of 1996 (as amended February 2008) and consists of two Corrective Action Sites (CASs): (1) CAS 25-23-20, Nuclear Furnace Piping; and (2) CAS 25-41-05, Test Cell C Facility. CAS 25-41-05 is described in the FFACO as the TCC Facility but actually includes Building 3210 and attached concrete shield wall only. CAU 116 will be closed by demolishing Building 3210, the attached concrete shield wall, and the nuclear furnace piping. In addition, as a best management practice (BMP), Building 3211 (moveable shed) will be demolished due to its close proximity to Building 3210. This will aid in demolition and disposal operations. Radiological surveys will be performed on the demolition debris to determine the proper disposal pathway. As much of the demolition debris as space allows will be placed into the Building 3210 basement structure. After filling to capacity with demolition debris, the basement structure will be mounded or capped and closed with administrative controls. Prior to beginning demolition activities and according to an approved Sampling and Analysis Plan (SAP), representative sampling of surface areas that are known, suspected, or have the potential to contain hazardous constituents such as lead or polychlorinated biphenyls (PCBs) will be performed throughout all buildings and structures. Sections 2.3.2, 4.2.2.2, 4.2.2.3, 4.3, and 6.2.6.1 address the methodologies employed that assure the solid debris placed in the basement structure will not contain contaminants of concern (COCs) above hazardous waste levels. The anticipated post

  4. A Multiple Watershed Approach to Assessing the Effects of Habitat Restoration Actions on Anadromous and Resident Fish Populations, Technical Report 2003-2004.

    SciTech Connect

    Marmorek, David

    2004-03-01

    for future habitat restoration actions. Such designs are being developed concurrently with this project by several other groups in the Columbia Basin (RME Workgroup 2003, NMFS 2003, Hillman and Paulsen 2002, Hillman 2003). By addressing questions about habitat restoration and monitoring (in coordination with other related efforts), we hope that this project will catalyze a shift in the Basin's paradigm of habitat restoration, moving from implementation of individual watershed projects towards rigorously designed and monitored, multiwatershed, adaptive management experiments. The project involved three phases of work, which were closely integrated with various related and ongoing efforts in the region: (1) Scoping - We met with a Core Group of habitat experts and managers to scope out a set of testable habitat restoration hypotheses, identify candidate watersheds and recommend participants for a data evaluation workshop. (2) Data Assembly - We contacted over 80 scientists and managers to help evaluate the suitability of each candidate watershed's historical data for assessing the effectiveness of past restoration actions. We eventually settled on the Yakima, Wenatchee, Clearwater, and Salmon subbasins, and began gathering relevant data for these watersheds at a workshop with habitat experts and managers. Data assembly continued for several months after the workshop. (3) Data Analysis and Synthesis - We explored statistical approaches towards retrospectively analyzing the effects of restoration 'treatments' at nested spatial scales across multiple watersheds (Chapters 2-5 of this report). These analyses provided a foundation for identifying existing constraints to testing restoration hypotheses, and opportunities to overcome these constraints through improved experimental designs, monitoring protocols and project selection strategies (Chapters 6 and 7 of this report). Finally, we developed a set of recommendations to improve the design, implementation, and monitoring of

  5. Comparative ecotoxicological hazard assessment of beta-blockers and their human metabolites using a mode-of-action-based test battery and a QSAR approach.

    PubMed

    Escher, Beate I; Bramaz, Nadine; Richter, Manuela; Lienert, Judit

    2006-12-01

    We analyzed nontarget effects of the beta-blockers propranolol, metoprolol, and atenolol with a screening test battery encompassing nonspecific, receptor-mediated, and reactive modes of toxic action. All beta-blockers were baseline toxicants and showed no specific effects on energy transduction nor endocrine activity in the yeast estrogen and androgen screen, and no reactive toxicity toward proteins and DNA. However, in a phytotoxicity assay based on the inhibition of the photosynthesis efficiency in green algae, all beta-blockers were 10 times more toxic than their modeled baseline toxicity. Baseline- and phytotoxicity effects increased with hydrophobicity. The beta-blockers showed concentration addition in mixture experiments, indicating a mutual specific nontarget effect on algae. Using literature data and quantitative structure-activity relationships (QSAR), we modeled the total toxic potential of mixtures of the beta-blockers and their associated human metabolites for the phytotoxicity endpoint with two scenarios. The realistic scenario (I) assumes that the metabolites lose their specific activity and act as baseline toxicants. In the worst-case scenario (II) the metabolites exhibitthe same specific mode of action as their parent drug. For scenario (II), metabolism hardly affected the overall toxicity of atenolol and metoprolol, whereas propranolol's hazard potential decreased significantly. In scenario (I), metabolism reduced the apparent EC50 of the mixture of parent drug and metabolite even further. The proposed method is a simple approach to initial hazard assessment of pharmaceuticals and can guide higher tier testing. It can be applied to other classes of pollutants, e.g., biocides, as well as to environmental transformation products of pollutants.

  6. The accountability for reasonableness approach to guide priority setting in health systems within limited resources – findings from action research at district level in Kenya, Tanzania, and Zambia

    PubMed Central

    2014-01-01

    Background Priority-setting decisions are based on an important, but not sufficient set of values and thus lead to disagreement on priorities. Accountability for Reasonableness (AFR) is an ethics-based approach to a legitimate and fair priority-setting process that builds upon four conditions: relevance, publicity, appeals, and enforcement, which facilitate agreement on priority-setting decisions and gain support for their implementation. This paper focuses on the assessment of AFR within the project REsponse to ACcountable priority setting for Trust in health systems (REACT). Methods This intervention study applied an action research methodology to assess implementation of AFR in one district in Kenya, Tanzania, and Zambia, respectively. The assessments focused on selected disease, program, and managerial areas. An implementing action research team of core health team members and supporting researchers was formed to implement, and continually assess and improve the application of the four conditions. Researchers evaluated the intervention using qualitative and quantitative data collection and analysis methods. Results The values underlying the AFR approach were in all three districts well-aligned with general values expressed by both service providers and community representatives. There was some variation in the interpretations and actual use of the AFR in the decision-making processes in the three districts, and its effect ranged from an increase in awareness of the importance of fairness to a broadened engagement of health team members and other stakeholders in priority setting and other decision-making processes. Conclusions District stakeholders were able to take greater charge of closing the gap between nationally set planning and the local realities and demands of the served communities within the limited resources at hand. This study thus indicates that the operationalization of the four broadly defined and linked conditions is both possible and seems to

  7. Covert Action: A Systems Approach

    DTIC Science & Technology

    2014-12-01

    Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND...Practical Common Sense (Anaheim, CA : KNI, Inc., 1998), 16. 3 of analysis. Analyzing the complex interplay of the covert action’s components and tradeoffs...Cullather, Secret History: The CIA’s Classified Account of Its Operations in Guatemala 1952– 1954 (Stanford, CA : Stanford University Press, 1999), 7. 30

  8. Environmental Awareness; An Action Approach.

    ERIC Educational Resources Information Center

    Wight, Edgar L.; And Others

    In the changing world of today, man has created alarming imbalances of nature which threaten all living creatures of the earth. The public is becoming aware that severe measures must be taken to correct these imbalances. Indian people are closely attuned to their lands and resources--it is part of their traditional culture to have close ties with…

  9. Action representation: crosstalk between semantics and pragmatics.

    PubMed

    Prinz, Wolfgang

    2014-03-01

    Marc Jeannerod pioneered a representational approach to movement and action. In his approach, motor representations provide both, declarative knowledge about action and procedural knowledge for action (action semantics and action pragmatics, respectively). Recent evidence from language comprehension and action simulation supports the claim that action pragmatics and action semantics draw on common representational resources, thus challenging the traditional divide between declarative and procedural action knowledge. To account for these observations, three kinds of theoretical frameworks are discussed: (i) semantics is grounded in pragmatics, (ii) pragmatics is anchored in semantics, and (iii) pragmatics is part and parcel of semantics.

  10. In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.

    PubMed

    Kirkland, D J; Aardema, M; Banduhn, N; Carmichael, P; Fautz, R; Meunier, J-R; Pfuhler, S

    2007-05-01

    A recent analysis by Kirkland et al. [Kirkland, D., Aardema, M., Henderson, L. and Müller, L. (2005) Evaluation of the ability of a battery of 3 in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity. Mutat. Res. 584, 1-256] demonstrated an extremely high false positive rate for in vitro genotoxicity tests when compared with carcinogenicity in rodents. In many industries, decisions have to be made on the safety of new substances, and health risk to humans, without rodent carcinogenicity data being available. In such cases, the usual way to determine whether a positive in vitro genotoxicity result is relevant (i.e. indicates a hazard) for humans is to develop weight of evidence (WoE) or mode of action (MoA) arguments. These are based partly on further in vitro investigations, but usually rely heavily on tests for genotoxicity in one or more in vivo assays. However, for certain product types in the European Union, the use of animals for genotoxicity testing (as well as for other endpoints) will be prohibited within the next few years. Many different examples have been described that indicate DNA damage and genotoxic responses in vitro can arise through non-relevant in vitro events that are a result of the test systems and conditions used. The majority of these non-relevant in vitro events can be grouped under a category of 'overload of normal physiology' that would not be expected to occur in exposed humans. However, obtaining evidence in support of such MoAs is not easy, particularly for those industries prohibited from carrying out in vivo testing. It will become necessary to focus on in vitro studies to provide evidence of non-DNA, threshold or in vitro-specific processes and to discuss the potential for such genotoxic effects to occur in exposed humans. Toward this end, we surveyed the published literature for in vitro approaches that may be followed to determine whether a

  11. Complementary actions.

    PubMed

    Sartori, Luisa; Betti, Sonia

    2015-01-01

    Complementary colors are color pairs which, when combined in the right proportions, produce white or black. Complementary actions refer here to forms of social interaction wherein individuals adapt their joint actions according to a common aim. Notably, complementary actions are incongruent actions. But being incongruent is not sufficient to be complementary (i.e., to complete the action of another person). Successful complementary interactions are founded on the abilities: (i) to simulate another person's movements, (ii) to predict another person's future action/s, (iii) to produce an appropriate incongruent response which differ, while interacting, with observed ones, and (iv) to complete the social interaction by integrating the predicted effects of one's own action with those of another person. This definition clearly alludes to the functional importance of complementary actions in the perception-action cycle and prompts us to scrutinize what is taking place behind the scenes. Preliminary data on this topic have been provided by recent cutting-edge studies utilizing different research methods. This mini-review aims to provide an up-to-date overview of the processes and the specific activations underlying complementary actions.

  12. Complementary actions

    PubMed Central

    Sartori, Luisa; Betti, Sonia

    2015-01-01

    Complementary colors are color pairs which, when combined in the right proportions, produce white or black. Complementary actions refer here to forms of social interaction wherein individuals adapt their joint actions according to a common aim. Notably, complementary actions are incongruent actions. But being incongruent is not sufficient to be complementary (i.e., to complete the action of another person). Successful complementary interactions are founded on the abilities: (i) to simulate another person’s movements, (ii) to predict another person’s future action/s, (iii) to produce an appropriate incongruent response which differ, while interacting, with observed ones, and (iv) to complete the social interaction by integrating the predicted effects of one’s own action with those of another person. This definition clearly alludes to the functional importance of complementary actions in the perception–action cycle and prompts us to scrutinize what is taking place behind the scenes. Preliminary data on this topic have been provided by recent cutting-edge studies utilizing different research methods. This mini-review aims to provide an up-to-date overview of the processes and the specific activations underlying complementary actions. PMID:25983717

  13. WIPP Sampling and Analysis Plan for Solid Waste Management Units and Areas of Concern

    SciTech Connect

    None, None

    2000-05-23

    This Sampling and Analysis Plan (SAP) has been prepared to fulfill requirements of Module VII, Section VII.M.2 and Table VII.1, requirement 4 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Permit, NM4890139088-TSDF (the Permit); (NMED [New Mexico Environment Department], 1999a). This SAP describes the approach for investigation of the Solid Waste Management Units (SWMU) and Areas of Concern (AOC) specified in the Permit. This SAP addresses the current Permit requirements for a RCRA Facility Investigation(RFI) investigation of SWMUs and AOCs. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the RFI specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI work plan and report sequence with a more flexible decision-making approach. The ACAA process allows a facility to exit the schedule of compliance contained in the facility's Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA process can beentered either before or after a RFI work plan. According to NMED's guidance, a facility can prepare a RFI work plan or SAP for any SWMU or AOC (NMED, 1998).

  14. Action Research: Trends and Variations

    ERIC Educational Resources Information Center

    Beaulieu, Rodney J.

    2013-01-01

    Action research continues to grow as a research tradition, yet misconceptions about what it is and is not remains, even among scholars. For example, some mistakenly believe action research is only about professional development and is not a scholarly research approach. Some assume action research must be accomplished through a collaborative…

  15. Action and familiarity effects on self and other expert musicians' Laban effort-shape analyses of expressive bodily behaviors in instrumental music performance: a case study approach.

    PubMed

    Broughton, Mary C; Davidson, Jane W

    2014-01-01

    Self-reflective performance review and expert evaluation are features of Western music performance practice. While music is usually the focus, visual information provided by performing musicians' expressive bodily behaviors communicates expressiveness to musically trained and untrained observers. Yet, within a seemingly homogenous group, such as one of musically trained individuals, diversity of experience exists. Individual differences potentially affect perception of the subtleties of expressive performance, and performers' effective communication of their expressive intentions. This study aimed to compare self- and other expert musicians' perception of expressive bodily behaviors observed in marimba performance. We hypothesized that analyses of expressive bodily behaviors differ between expert musicians according to their specialist motor expertise and familiarity with the music. Two professional percussionists and experienced marimba players, and one professional classical singer took part in the study. Participants independently conducted Laban effort-shape analysis - proposing that intentions manifest in bodily activity are understood through shared embodied processes - of a marimbists' expressive bodily behaviors in an audio-visual performance recording. For one percussionist, this was a self-reflective analysis. The work was unfamiliar to the other percussionist and singer. Perception of the performer's expressive bodily behaviors appeared to differ according to participants' individual instrumental or vocal motor expertise, and familiarity with the music. Furthermore, individual type of motor experience appeared to direct participants' attention in approaching the analyses. Findings support forward and inverse perception-action models, and embodied cognitive theory. Implications offer scientific rigor and artistic interest for how performance practitioners can reflectively analyze performance to improve expressive communication.

  16. Action and familiarity effects on self and other expert musicians’ Laban effort-shape analyses of expressive bodily behaviors in instrumental music performance: a case study approach

    PubMed Central

    Broughton, Mary C.; Davidson, Jane W.

    2014-01-01

    Self-reflective performance review and expert evaluation are features of Western music performance practice. While music is usually the focus, visual information provided by performing musicians’ expressive bodily behaviors communicates expressiveness to musically trained and untrained observers. Yet, within a seemingly homogenous group, such as one of musically trained individuals, diversity of experience exists. Individual differences potentially affect perception of the subtleties of expressive performance, and performers’ effective communication of their expressive intentions. This study aimed to compare self- and other expert musicians’ perception of expressive bodily behaviors observed in marimba performance. We hypothesized that analyses of expressive bodily behaviors differ between expert musicians according to their specialist motor expertise and familiarity with the music. Two professional percussionists and experienced marimba players, and one professional classical singer took part in the study. Participants independently conducted Laban effort-shape analysis – proposing that intentions manifest in bodily activity are understood through shared embodied processes – of a marimbists’ expressive bodily behaviors in an audio-visual performance recording. For one percussionist, this was a self-reflective analysis. The work was unfamiliar to the other percussionist and singer. Perception of the performer’s expressive bodily behaviors appeared to differ according to participants’ individual instrumental or vocal motor expertise, and familiarity with the music. Furthermore, individual type of motor experience appeared to direct participants’ attention in approaching the analyses. Findings support forward and inverse perception–action models, and embodied cognitive theory. Implications offer scientific rigor and artistic interest for how performance practitioners can reflectively analyze performance to improve expressive communication. PMID

  17. Action Learning.

    ERIC Educational Resources Information Center

    1996

    These four papers were presented at a symposium on action learning moderated by Lex Dilworth at the 1996 conference of the Academy of Human Resource Development. "Developing an Infrastructure for Individual and Organizational Change: Transfer of Learning from an Action Reflection Learning (ARL) Program" (ARL Inquiry) reports findings…

  18. Cardiac action potential imaging

    NASA Astrophysics Data System (ADS)

    Tian, Qinghai; Lipp, Peter; Kaestner, Lars

    2013-06-01

    Action potentials in cardiac myocytes have durations in the order of magnitude of 100 milliseconds. In biomedical investigations the documentation of the occurrence of action potentials is often not sufficient, but a recording of the shape of an action potential allows a functional estimation of several molecular players. Therefore a temporal resolution of around 500 images per second is compulsory. In the past such measurements have been performed with photometric approaches limiting the measurement to one cell at a time. In contrast, imaging allows reading out several cells at a time with additional spatial information. Recent developments in camera technologies allow the acquisition with the required speed and sensitivity. We performed action potential imaging on isolated adult cardiomyocytes of guinea pigs utilizing the fluorescent membrane potential sensor di-8-ANEPPS and latest electron-multiplication CCD as well as scientific CMOS cameras of several manufacturers. Furthermore, we characterized the signal to noise ratio of action potential signals of varying sets of cameras, dye concentrations and objective lenses. We ensured that di-8-ANEPPS itself did not alter action potentials by avoiding concentrations above 5 μM. Based on these results we can conclude that imaging is a reliable method to read out action potentials. Compared to conventional current-clamp experiments, this optical approach allows a much higher throughput and due to its contact free concept leaving the cell to a much higher degree undisturbed. Action potential imaging based on isolated adult cardiomyocytes can be utilized in pharmacological cardiac safety screens bearing numerous advantages over approaches based on heterologous expression of hERG channels in cell lines.

  19. Action perception predicts action performance

    PubMed Central

    Bailey, Heather R.; Kurby, Christopher A.; Giovannetti, Tania; Zacks, Jeffrey M.

    2013-01-01

    Everyday action impairments often are observed in demented older adults, and they are common potential barriers to functional independence. We evaluated whether the ability to segment and efficiently encode activities is related to the ability to execute activities. Further, we evaluated whether brain regions important for segmentation also were important for action performance. Cognitively healthy older adults and those with very mild or mild dementia of the Alzheimer's type watched and segmented movies of everyday activities and then completed the Naturalistic Action Test. Structural MRI was used to measure volume in the dorsolateral prefrontal cortex (DLPFC), medial temporal lobes (MTL), posterior cortex, and anterior cingulate cortex (ACC). Dementia status and the ability to segment everyday activities strongly predicted naturalistic action performance, and MTL volume largely accounted for this relationship. In addition, the current results supported the Omission-Commission Model: Different cognitive and neurological mechanisms predicted different types of action error. Segmentation, dementia severity, and MTL volume predicted everyday omission errors, DLPFC volume predicted commission errors, and ACC volume predicted action additions. These findings suggest that event segmentation may be critical for effective action production, and that the segmentation and production of activities may recruit the same event representation system. PMID:23851113

  20. Action perception predicts action performance.

    PubMed

    Bailey, Heather R; Kurby, Christopher A; Giovannetti, Tania; Zacks, Jeffrey M

    2013-09-01

    Everyday action impairments often are observed in demented older adults, and they are common potential barriers to functional independence. We evaluated whether the ability to segment and efficiently encode activities is related to the ability to execute activities. Further, we evaluated whether brain regions important for segmentation also were important for action performance. Cognitively healthy older adults and those with very mild or mild dementia of the Alzheimer's type watched and segmented movies of everyday activities and then completed the Naturalistic Action Test. Structural MRI was used to measure volume in the dorsolateral prefrontal cortex (DLPFC), medial temporal lobes (MTL), posterior cortex, and anterior cingulate cortex (ACC). Dementia status and the ability to segment everyday activities strongly predicted naturalistic action performance, and MTL volume largely accounted for this relationship. In addition, the current results supported the Omission-Commission Model: Different cognitive and neurological mechanisms predicted different types of action error. Segmentation, dementia severity, and MTL volume predicted everyday omission errors, DLPFC volume predicted commission errors, and ACC volume predicted action additions. These findings suggest that event segmentation may be critical for effective action production, and that the segmentation and production of activities may recruit the same event representation system.

  1. Granularity within the mirror system is not informative on action perception. Comment on "Grasping synergies: A motor-control approach to the mirror neuron mechanism" by D'Ausilio et al.

    NASA Astrophysics Data System (ADS)

    Cattaneo, Luigi

    2015-03-01

    The present work [1] reviews a part of the now vast literature on visuomotor stimulus-response associations in the domain of action observation, commonly referred to as mirror mechanism or mirror system. The aim of the study is to propose a solution to a currently debated problem, namely in what frame of reference are mirror neurons coding movement. The solution proposed here is that, if the mirror system is part of the motor system, then the motor responses to action observation must be in the same frames of reference as that generally observed in the production of voluntary actions. This idea is part of the very first conceptualizations of the mirror system ("Each time an individual sees an action done by another individual, neurons that represent that action are activated in the observer's premotor cortex. This automatically induced, motor representation of the observed action corresponds to that which is spontaneously generated during active action and whose outcome is known to the acting individual" [2]) and has been explicitly proposed earlier [3] in the attempt of reconciling the very different findings in the literature on the mirror system's frames of reference. The novelty of the present approach is the explicit reference to the 'motor synergy' theory of voluntary hand movements. This theory states that the high number of degrees of freedom intrinsic to hand anatomy is reduced by the motor system to few principal components named motor synergies that are the building blocks of voluntary behavior [4]. I am enthusiastic about two points proposed by D'Ausilio in the present review and I am skeptical about some other points.

  2. Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 357: Mud Pits and Waste Dump, Nevada Test Site, Nevada: Revision 0, Including Record of Technical Change No. 1

    SciTech Connect

    2003-06-25

    This Streamlined Approach for Environmental Restoration (SAFER) plan was prepared as a characterization and closure report for Corrective Action Unit (CAU) 357, Mud Pits and Waste Dump, in accordance with the Federal Facility Agreement and Consent Order. The CAU consists of 14 Corrective Action Sites (CASs) located in Areas 1, 4, 7, 8, 10, and 25 of the Nevada Test Site (NTS). All of the CASs are found within Yucca Flat except CAS 25-15-01 (Waste Dump). Corrective Action Site 25-15-01 is found in Area 25 in Jackass Flat. Of the 14 CASs in CAU 357, 11 are mud pits, suspected mud pits, or mud processing-related sites, which are by-products of drilling activities in support of the underground nuclear weapons testing done on the NTS. Of the remaining CASs, one CAS is a waste dump, one CAS contains scattered lead bricks, and one CAS has a building associated with Project 31.2. All 14 of the CASs are inactive and abandoned. Clean closure with no further action of CAU 357 will be completed if no contaminants are detected above preliminary action levels. A closure report will be prepared and submitted to the Nevada Division of Environmental Protection for review and approval upon completion of the field activities. Record of Technical Change No. 1 is dated 3/2004.

  3. Action Recognition Using Visual-Neuron Feature

    NASA Astrophysics Data System (ADS)

    Li, Ning; Xu, De

    This letter proposes a neurobiological approach for action recognition. In this approach, actions are represented by a visual-neuron feature (VNF) based on a quantitative model of object representation in the primate visual cortex. A supervised classification technique is then used to classify the actions. The proposed VNF is invariant to affine translation and scaling of moving objects while maintaining action specificity. Moreover, it is robust to the deformation of actors. Experiments on publicly available action datasets demonstrate the proposed approach outperforms conventional action recognition models based on computer-vision features.

  4. Streamlined approach for environmental restoration workplan for Corrective Action Unit 198: Test Cell C filter tank closure, Nevada Test Site, Nevada. Revision 1

    SciTech Connect

    1998-07-01

    This plan addresses characterization and closure of Corrective Action Unit (CAU) 198 identified in the Federal Facility Agreement and Consent Order. The site is located at the Nevada Test Site (NTS) Area 25 Test Cell C Complex. The CAU consists of one Corrective Action Site (CAS) 25-23-12 which includes two aboveground radioactive wastewater filter tanks. The tanks have an estimated capacity of 2,271 liters (600 gallons) each and were used to filter radioactive wastewater originating from the Test Cell C ``Nuclear Furnace 1`` testing. The tanks contain radioisotopes. Process knowledge indicates that the most likely isotopes of concern include {sup 90}Strontium and {sup 137}Cesium.

  5. Blogs and the Development of Plurilingual and Intercultural Competence: Report of a Co-Actional Approach in Portuguese Foreign Language Classroom

    ERIC Educational Resources Information Center

    Melo-Pfeifer, Sílvia

    2015-01-01

    Focusing on the topic of the development of the plurilingual and intercultural competence through the integration of electronic communicative practices both in foreign language classrooms and non-formal contexts, this work aims at defining and characterizing, in view of a co-actional perspective, a "pedagogical blog", by considering it…

  6. State Action on Sex Equity in Vocational Education. A Compilation of Selected States' Approaches to the Legislated Functions of Full-Time Sex Equity Personnel in Vocational Education.

    ERIC Educational Resources Information Center

    Ellis Associates, Inc., College Park, MD.

    Intended to aid the personnel hired by the states to coordinate and supervise their sex equity efforts in vocational education, this handbook contains brief descriptions of what fifteen states (which were chosen to participate in a workshop on the development of action models to eliminate sex stereotyping from vocational education) have done, and…

  7. VIOLENT FRAMES IN ACTION

    SciTech Connect

    Sanfilippo, Antonio P.; McGrath, Liam R.; Whitney, Paul D.

    2011-11-17

    We present a computational approach to radical rhetoric that leverages the co-expression of rhetoric and action features in discourse to identify violent intent. The approach combines text mining and machine learning techniques with insights from Frame Analysis and theories that explain the emergence of violence in terms of moral disengagement, the violation of sacred values and social isolation in order to build computational models that identify messages from terrorist sources and estimate their proximity to an attack. We discuss a specific application of this approach to a body of documents from and about radical and terrorist groups in the Middle East and present the results achieved.

  8. Action Research: Theory and Applications

    ERIC Educational Resources Information Center

    Jefferson, Renée N.

    2014-01-01

    Action research as a methodology is suitable for use within academic library settings. Its theoretical foundations are located in several disciplines and its applications span across many professions. In this article, an overview of the theoretical beginnings and evolution of action research is presented. Approaches generally used in conducting an…

  9. Action Learning in the BBC

    ERIC Educational Resources Information Center

    Felix, Eversley; Keevill, Joan

    2008-01-01

    This account tells the story of the development of an action learning culture in the BBC between 2002 and 2007. From its early beginnings as a sporadic, unsystematic intervention with a small number of leaders scattered throughout the organisation, action learning has now become embedded in our approach to the way we develop our leaders. In this…

  10. Community Action for Environmental Quality.

    ERIC Educational Resources Information Center

    Citizens Advisory Committee on Environmental Quality.

    For citizens who want to participate in practical action to make their communities better places for living, this guide considers numerous approaches for community involvement. It stresses not only comprehensive planning but also the importance of getting action started. A rough order of business is suggested. First, considered are the various…

  11. The Concept of Action Research.

    ERIC Educational Resources Information Center

    Altrichter, Herbert; Kemmis, Stephen; McTaggart, Robin; Zuber-Skerritt, Ortrun

    2002-01-01

    Explains why definition of action research is problematic and presents working definitions developed internationally that indicate its nature, philosophy, and methodology. Suggests that pragmatic approaches to definition serve communication purposes without narrowly confining the concept. (SK)

  12. Streamlined approach for environmental restoration closure report for Corrective Action Unit 120: Areas 5 and 6 aboveground storage tanks, Nevada Test Site, Nevada

    SciTech Connect

    1999-06-01

    This Closure Report provides documentation for the closure of Corrective Action Unit (CAU) 120 of the Federal Facilities Agreement and Consent Order (FFACO). CAU 120 consists of two Corrective Action Sites (CASs) located in Areas 5 and 6 of the Nevada Test Site (NTS), which are approximately 130 kilometers (80 miles) northwest of Las Vegas, Nevada. CAS 05-01-01 is located in Area 5 and consists of three 45,800-liter (12,100-gallon) aboveground storage tanks (ASTs), piping, and debris associated with Well RNM-1. CAS 06-01-01 consists of two ASTs and two tanker trailers (all portable) that were originally located at the Area 6 Cp-50 Hot Park and which had been moved to the Area 6 Waste Handling Facility. All of the items in CAU 120 have been used to contain or convey radiologically contaminated fluid that was generated during post-nuclear event activities at the NTS.

  13. "Wuwei" (Non-Action) Philosophy and Actions: Rethinking "Actions" in School Reform

    ERIC Educational Resources Information Center

    Moon, Seungho

    2015-01-01

    This inquiry aims to enrich conversation regarding school reform. The author asks about what other discourses are possible when the action-oriented question of how to "act" is a major approach to "fix" current educational problems. Drawing from Taoist philosophy of "wuwei" (non-action), the author provides a frame to…

  14. ACAA pavement manual. Recommended practice: Coal fly ash in pozzolanic stabilized mixtures for flexible pavement systems

    SciTech Connect

    Not Available

    1991-01-01

    The purpose of this manual is to guide pavement design engineers, materials engineers, and construction managers in the design and construction of flexible pavement systems in which low- to high-strength Pozzolanic Stabilized Mixtures' ( PSMs') serve as base layers. A PSM incorporates coal fly ash in combination with activators, aggregates and water. Each of three design methods is useful for determining the thickness of a PSM base layer for a flexible pavement system: Method A - American Association of State Highway and Transportation Officials (AASHTO) flexible pavement design procedures, using structural layer coefficients; Method B - Mechanistic pavement design procedures, using resilient modulus values for the pavement layers; and Method C - A combination of Method A and Method B, using mechanistic design concepts for determining pavement layer coefficients. PSMs offer several advantages: PSMs are strong, durable mixtures using locally available materials; PSMs are economically competitive with properly engineered full-depth asphalt or crushed stone base courses; PSMs are suited to stabilizing recycled base mixtures; and PSMs are placed and compacted with conventional construction equipment. To provide the needed guidance for capturing the long-term service and cost-saving features of a PSM design, this manual details the following: a procedure for proportioning PSMs; thickness design procedures which include base layer and asphalt wearing course; and proven techniques for PSM mixing and base layer construction.

  15. Everyday robotic action: lessons from human action control

    PubMed Central

    de Kleijn, Roy; Kachergis, George; Hommel, Bernhard

    2014-01-01

    Robots are increasingly capable of performing everyday human activities such as cooking, cleaning, and doing the laundry. This requires the real-time planning and execution of complex, temporally extended sequential actions under high degrees of uncertainty, which provides many challenges to traditional approaches to robot action control. We argue that important lessons in this respect can be learned from research on human action control. We provide a brief overview of available psychological insights into this issue and focus on four principles that we think could be particularly beneficial for robot control: the integration of symbolic and subsymbolic planning of action sequences, the integration of feedforward and feedback control, the clustering of complex actions into subcomponents, and the contextualization of action-control structures through goal representations. PMID:24672474

  16. Everyday robotic action: lessons from human action control.

    PubMed

    de Kleijn, Roy; Kachergis, George; Hommel, Bernhard

    2014-01-01

    Robots are increasingly capable of performing everyday human activities such as cooking, cleaning, and doing the laundry. This requires the real-time planning and execution of complex, temporally extended sequential actions under high degrees of uncertainty, which provides many challenges to traditional approaches to robot action control. We argue that important lessons in this respect can be learned from research on human action control. We provide a brief overview of available psychological insights into this issue and focus on four principles that we think could be particularly beneficial for robot control: the integration of symbolic and subsymbolic planning of action sequences, the integration of feedforward and feedback control, the clustering of complex actions into subcomponents, and the contextualization of action-control structures through goal representations.

  17. THE TWO-LEVEL THEORY OF VERB MEANING: AN APPROACH TO INTEGRATING THE SEMANTICS OF ACTION WITH THE MIRROR NEURON SYSTEM

    PubMed Central

    Kemmerer, David; Castillo, Javier Gonzalez

    2010-01-01

    Verbs have two separate levels of meaning. One level reflects the uniqueness of every verb and is called the “root.” The other level consists of a more austere representation that is shared by all the verbs in a given class and is called the “event structure template.” We explore the following hypotheses about how, with specific reference to the motor features of action verbs, these two distinct levels of semantic representation might correspond to two distinct levels of the mirror neuron system. Hypothesis 1: Root-level motor features of verb meaning are partially subserved by somatotopically mapped mirror neurons in the left primary motor and/or premotor cortices. Hypothesis 2: Template-level motor features of verb meaning are partially subserved by representationally more schematic mirror neurons in Brodmann area 44 of the left inferior frontal gyrus. Evidence has been accumulating in support of the general neuroanatomical claims made by these two hypotheses—namely, that each level of verb meaning is associated with the designated cortical areas. However, as yet no studies have satisfied all the criteria necessary to support the more specific neurobiological claims made by the two hypotheses—namely, that each level of verb meaning is associated with mirror neurons in the pertinent brain regions. This would require demonstrating that within those regions the same neuronal populations are engaged during (a) the linguistic processing of particular motor features of verb meaning, (b) the execution of actions with the corresponding motor features, and (c) the observation of actions with the corresponding motor features. PMID:18996582

  18. The Key Events Dose-Response Framework: A cross-Disciplinary Mode-of-Action Based Approach to Examining Does-Response and Thresholds

    EPA Science Inventory

    the ILSI Research Foundation conveded a cross-disciplinary working group to examine current approaches for assessing dose-response and identifying safe levels of intake or exposure for four categoreis of bioactive agents: food allergens, nutrients, pathogenic microorganisms, and ...

  19. Conscious Action/Zombie Action

    PubMed Central

    Shepherd, Joshua

    2015-01-01

    Abstract I argue that the neural realizers of experiences of trying (that is, experiences of directing effort towards the satisfaction of an intention) are not distinct from the neural realizers of actual trying (that is, actual effort directed towards the satisfaction of an intention). I then ask how experiences of trying might relate to the perceptual experiences one has while acting. First, I assess recent zombie action arguments regarding conscious visual experience, and I argue that contrary to what some have claimed, conscious visual experience plays a causal role for action control in some circumstances. Second, I propose a multimodal account of the experience of acting. According to this account, the experience of acting is (at the very least) a temporally extended, co‐conscious collection of agentive and perceptual experiences, functionally integrated and structured both by multimodal perceptual processing as well as by what an agent is, at the time, trying to do. PMID:27667859

  20. Conscious Action/Zombie Action.

    PubMed

    Shepherd, Joshua

    2016-06-01

    I argue that the neural realizers of experiences of trying (that is, experiences of directing effort towards the satisfaction of an intention) are not distinct from the neural realizers of actual trying (that is, actual effort directed towards the satisfaction of an intention). I then ask how experiences of trying might relate to the perceptual experiences one has while acting. First, I assess recent zombie action arguments regarding conscious visual experience, and I argue that contrary to what some have claimed, conscious visual experience plays a causal role for action control in some circumstances. Second, I propose a multimodal account of the experience of acting. According to this account, the experience of acting is (at the very least) a temporally extended, co-conscious collection of agentive and perceptual experiences, functionally integrated and structured both by multimodal perceptual processing as well as by what an agent is, at the time, trying to do.

  1. Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 120: Areas 5 and 6 Aboveground Storage Tanks, Nevada Test Site, Nevada

    SciTech Connect

    Allison Urban

    1999-06-01

    This Closure Report provides documentation for the closure of Corrective Action Unit 120. CAU 120 consists of two Corrective Action Sites located in Areas 5 and 6 of the Nevada Test Site. CAS 05-01-01 is located in Area 5 and consists of three 45,800-liter aboveground storage tanks, piping, and debris associated with Well RNM-1. CAS 06-01-01 in Area 6 consists of two aboveground storage tanks and two tanker trailers All the CAU 120 items have been used to convey or contain radiologically contaminated fluid from post-nuclear event activities at the NTS> Closure of this CAU was completed by collecting samples to identify the appropriate method of disposal for tanks, piping, debris, and tankers in each CAS. Placing low-level radioactive waste into the appropriate containers and disposing of waste in the Area 5 Radioactive Waste Management Site, the Area 9 10C Landfill, and the Area 3 Radioactive Waste Management Site.

  2. Impact of Community-Based Approach as Policy Tool: World Health Organization-Designated Safe Communities of Korea and Health Action Zones of the United Kingdom

    PubMed Central

    Kang, Changhyun; Shin, Jihyung; Matthews, Bob

    2015-01-01

    Objectives The aim of this study is to ascertain and identify the effectiveness of area-based initiatives as a policy tool mediated by societal and individual factors in the five World Health Organization (WHO)-designated Safe Communities of Korea and the Health Action Zones of the United Kingdom (UK). Methods The Korean National Hospital discharge in-depth injury survey from the Korea Centers for Disease Control and Prevention and causes of death statistics by the Statistics Korea were used for all analyses. The trend and changes in injury rate and mortality by external causes were compared among the five WHO-designated Safe Communities in Korea. Results The injury incident rates decreased at a greater level in the Safe Communities compared with the national average. Similar results were shown for the changes in unintentional injury incident rates. In comparison of changes in mortality rate by external causes between 2005 and 2011, the rate increase in Safe Communities was higher than the national average except for Jeju, where the mortality rate by external causes decreased. Conclusion When the Healthy Action Zones of the UK and the WHO Safe Communities of Korea were examined, the outcomes were interpreted differently among the compared index, regions, and time periods. Therefore, qualitative outcomes, such as bringing the residents' attention to the safety of the communities and promoting participation and coordination of stakeholders, should also be considered as important impacts of the community-based initiatives. PMID:26981341

  3. Irmpd Action Spectroscopy and Computational Approaches to Elucidate Gas-Phase Structures and Energetics of 2'-DEOXYCYTIDINE and Cytidine Sodium Complexes

    NASA Astrophysics Data System (ADS)

    Zhu, Yanlong; Hamlow, Lucas; He, Chenchen; Gao, Juehan; Oomens, Jos; Rodgers, M. T.

    2016-06-01

    The local structures of DNA and RNA are influenced by protonation, deprotonation and noncovalent interactions with cations. In order to determine the effects of Na+ cationization on the gas-phase structures of 2'-deoxycytidine, [dCyd+Na]+, and cytidine, [Cyd+Na]+, infrared multiple photon dissociation (IRMPD) action spectra of these sodium cationized nucleosides are measured over the range extending from 500 to 1850 wn using the FELIX free electron laser. Complementary electronic structure calculations are performed to determine the stable low-energy conformations of these complexes. Geometry optimizations, frequency analyses, and IR spectra of these species are determined at the B3LYP/6-311+G(d,p) level of theory. Single-point energies are calculated at the B3LYP/6-311+G(2d,2p) level of theory to determine the relative stabilities of these conformations. Comparison of the measure IRMPD action spectra and computed linear IR spectra enable the conformations accessed in the experiments to be elucidated. For both cytosine nucleosides, tridentate binding of the Na+ cation to the O2, O4' and O5' atoms of the nucleobase and sugar is observed. Present results for the sodium cationized nucleosides are compared to results for the analogous protonated forms of these nucleosides to elucidate the effects of multiple chelating interactions with the sodium cation vs. hydrogen bonding interactions in the protonated systems on the structures and stabilities of these nucleosides.

  4. Action Learning: Avoiding Conflict or Enabling Action

    ERIC Educational Resources Information Center

    Corley, Aileen; Thorne, Ann

    2006-01-01

    Action learning is based on the premise that action and learning are inextricably entwined and it is this potential, to enable action, which has contributed to the growth of action learning within education and management development programmes. However has this growth in action learning lead to an evolution or a dilution of Revan's classical…

  5. Mathematical models of radiation action on living cells: From the target theory to the modern approaches. A historical and critical review.

    PubMed

    Bodgi, Larry; Canet, Aurélien; Pujo-Menjouet, Laurent; Lesne, Annick; Victor, Jean-Marc; Foray, Nicolas

    2016-04-07

    Cell survival is conventionally defined as the capability of irradiated cells to produce colonies. It is quantified by the clonogenic assays that consist in determining the number of colonies resulting from a known number of irradiated cells. Several mathematical models were proposed to describe the survival curves, notably from the target theory. The Linear-Quadratic (LQ) model, which is to date the most frequently used model in radiobiology and radiotherapy, dominates all the other models by its robustness and simplicity. Its usefulness is particularly important because the ratio of the values of the adjustable parameters, α and β, on which it is based, predicts the occurrence of post-irradiation tissue reactions. However, the biological interpretation of these parameters is still unknown. Throughout this review, we revisit and discuss historically, mathematically and biologically, the different models of the radiation action by providing clues for resolving the enigma of the LQ model.

  6. Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia

    PubMed Central

    Wang, Xiumin; Teng, Da; Mao, Ruoyu; Yang, Na; Hao, Ya

    2016-01-01

    ABSTRACT A marine arenicin-3 derivative, N4, displayed potent antibacterial activity against Gram-negative bacteria, but its antibacterial mode of action remains elusive. The mechanism of action of N4 against pathogenic Escherichia coli was first researched by combined cytological and transcriptomic techniques in this study. The N4 peptide permeabilized the outer membrane within 1 min, disrupted the plasma membrane after 0.5 h, and localized in the cytoplasm within 5 min. Gel retardation and circular dichroism (CD) spectrum analyses demonstrated that N4 bound specifically to DNA and disrupted the DNA conformation from the B type to the C type. N4 inhibited 21.1% of the DNA and 20.6% of the RNA synthesis within 15 min. Several hallmarks of apoptosis-like cell death were exhibited by N4-induced E. coli, such as cell cycle arrest in the replication (R) and division(D) phases, reactive oxygen species production, depolarization of the plasma membrane potential, and chromatin condensation within 0.5 h. Deformed cell morphology, disappearance of the plasma membrane, leakage of the contents, and ghost cell formation were demonstrated by transmission electron microscopy, and nearly 100% of the bacteria were killed by N4. A total of 428 to 663 differentially expressed genes are involved in the response to N4, which are associated mainly with membrane biogenesis (53.9% to 56.7%) and DNA binding (13.3% to 14.9%). N4-protected mice that were lethally challenged with lipopolysaccharide (LPS) exhibited reduced levels of interleukin-6 (IL-6), IL-1β, and tumor necrosis factor alpha (TNF-α) in serum and protected the lungs from LPS-induced injury. These data facilitate an enhanced understanding of the mechanisms of marine antimicrobial peptides (AMPs) against Gram-negative bacteria and provide guidelines in developing and applying novel multitarget AMPs in the field of unlimited marine resources as therapeutics. PMID:27795369

  7. Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 198: Test Cell C Filter Tank Closure Nevada Test Site, Nevada

    SciTech Connect

    Jerry Bonn

    1998-12-01

    This closure report (CR) provides documentation for the closure of Corrective Action Unit (CAU) 198 identified in the Federal Facility Agreement and Consent Order (FFACO). The site is located at the Nevada Test Site (NTS) Area 25 Test Cell C Complex (Figure 1). The CAU consists of one Corrective Action Site (CAS) 25-23-12 which includes two aboveground radioactive wastewater filter tanks used during the Nuclear Furnace Testing at Test Cell C. The Test Cell C complex was one of several facilities dedicated to the development of nuclear rocket technology. Test Cell C was designed to test nuclear rocket reactors. Part of the testing program included Nuclear Furnace Tests. The Nuclear Furnace was a water-moderated, hydrogen-cooled, 44-megawatt reactor used to test fuel elements for the nuclear rocket engine. The Nuclear Furnace in itself was not a nuclear rocket engine. During testing, hydrogen exited the reactor at a temperature of 2,440 degrees Kelvin. Water was injected into the gas stream to cool the hydrogen and capture the various radiological isotopes. Hydrogen gas effluent was decontaminated through a multistage process before being burned at the Test Cell C flare stack. A by-product of the decontamination process produced water contaminated with mixed fission products. Prior to discharge to a tile drain system (CAU 267) the water was filtered through the two 2271-liters (600-gallon) filter tanks (Department of Energy [DOE], 1998). Reactor development, engine testing, and rocket development activities were ended in the early 1970s. The filter tanks have remained inactive since that time. The site is currently roped off and posted with ''Caution Radiation Area'' signs. The filter tanks were located on the east side of Test Cell C, approximately 15.2 meters (50 feet) from the facility fence line (Figure 2).

  8. The Key Events Dose-Response Framework: A Cross-Disciplinary Mode-of-Action Based Approach to Examining Dose-Response and Thresholds

    PubMed Central

    JULIEN, ELIZABETH; BOOBIS, ALAN R.; OLIN, STEPHEN S.

    2009-01-01

    The ILSI Research Foundation convened a cross-disciplinary working group to examine current approaches for assessing dose-response and identifying safe levels of intake or exposure for four categories of bioactive agents—food allergens, nutrients, pathogenic microorganisms, and environmental chemicals. This effort generated a common analytical framework—the Key Events Dose-Response Framework (KEDRF)—for systematically examining key events that occur between the initial dose of a bioactive agent and the effect of concern. Individual key events are considered with regard to factors that influence the dose-response relationship and factors that underlie variability in that relationship. This approach illuminates the connection between the processes occurring at the level of fundamental biology and the outcomes observed at the individual and population levels. Thus, it promotes an evidence-based approach for using mechanistic data to reduce reliance on default assumptions, to quantify variability, and to better characterize biological thresholds. This paper provides an overview of the KEDRF and introduces a series of four companion papers that illustrate initial application of the approach to a range of bioactive agents. PMID:19690994

  9. Communication: Wigner functions in action-angle variables, Bohr-Sommerfeld quantization, the Heisenberg correspondence principle, and a symmetrical quasi-classical approach to the full electronic density matrix

    NASA Astrophysics Data System (ADS)

    Miller, William H.; Cotton, Stephen J.

    2016-08-01

    It is pointed out that the classical phase space distribution in action-angle (a-a) variables obtained from a Wigner function depends on how the calculation is carried out: if one computes the standard Wigner function in Cartesian variables (p, x), and then replaces p and x by their expressions in terms of a-a variables, one obtains a different result than if the Wigner function is computed directly in terms of the a-a variables. Furthermore, the latter procedure gives a result more consistent with classical and semiclassical theory—e.g., by incorporating the Bohr-Sommerfeld quantization condition (quantum states defined by integer values of the action variable) as well as the Heisenberg correspondence principle for matrix elements of an operator between such states—and has also been shown to be more accurate when applied to electronically non-adiabatic applications as implemented within the recently developed symmetrical quasi-classical (SQC) Meyer-Miller (MM) approach. Moreover, use of the Wigner function (obtained directly) in a-a variables shows how our standard SQC/MM approach can be used to obtain off-diagonal elements of the electronic density matrix by processing in a different way the same set of trajectories already used (in the SQC/MM methodology) to obtain the diagonal elements.

  10. Streamlined Approach for Environmental Restoration Plan for Corrective Action Units 530, 531, 532, 533, 534, and 535, Nevada Test Site Mud Pits, Nevada Test Site, Nevada, Revision 0 with ROTC 1 and 2

    SciTech Connect

    Wickline, Alfred

    2005-07-01

    This Streamlined Approach for Environmental Restoration (SAFER) Plan addresses closure for the following six corrective action units (CAUs) identified in the ''Federal Facility Agreement and Consent Order'' (1996): (1) CAU 530 - LANL Preshot Mud Pits; (2) CAU 531 - LANL Postshot Mud Pits; (3) CAU 532 - LLNL Preshot Mud Pits; (4) CAU 533 - LLNL Postshot Mud Pits; (5) CAU 534 - Exploratory/Instrumentation Mud Pits; and (6) CAU 535 - Mud Pits/Disposal Areas. Corrective Action Units 530-535 consist of corrective action sites (CASs) located in Areas 1-10, 14, 17, 19, and 20 of the Nevada Test Site (NTS). This plan provides the approach for activities needed to gather the necessary information for closing all the CASs within these CAUs. There is sufficient information and process knowledge from historical documentation and investigations of similar sites regarding the expected nature and extent of potential contaminants to recommend closure of all CASs within CAUs 530-535 using the SAFER process. The Data Quality Objective (DQO) process utilized in this investigation follows the approved risk-based closure strategy outlined in the ''Mud Pit Risk-Based Closure Strategy Report'' (NNSA/NSO, 2004b). The closure strategy was developed based on available information including historical documentation of process knowledge, analytical results from previous sampling activities for contaminants of potential concern at similar mud pits located at the NTS and at off-site locations, future land-use scenarios for each NTS area, and potential exposure scenarios along with the calculated risk for human and ecological receptors.

  11. Social Action As An Objective of Social Studies Instruction.

    ERIC Educational Resources Information Center

    Curtis, Charles K.

    This paper presents a rationale for making social action a major goal of elementary and secondary school social studies education. In addition, it describes social action models, suggests social action approaches appropriate for students at various grade levels, and reviews literature on social action by public school students. Social action is…

  12. Knowledge and Action in Adult Education.

    ERIC Educational Resources Information Center

    Cogito, 1971

    1971-01-01

    Papers relating to using both knowledge and action in adult education programs are presented. The titles and authors of the papers are as follows: "Toward a Theory of Practice in Adult Education" by Jack Mezirow; "Action Seminars" by Alan Knox; The Case-Study Approach--Alternation between Knowledge and Action in Adult Education: (a) "Prepare Case…

  13. A Difference-in-Differences Approach to Assess the Effect of a Heat Action Plan on Heat-Related Mortality, and Differences in Effectiveness According to Sex, Age, and Socioeconomic Status (Montreal, Quebec)

    PubMed Central

    Benmarhnia, Tarik; Bailey, Zinzi; Kaiser, David; Auger, Nathalie; King, Nicholas; Kaufman, Jay S.

    2016-01-01

    Background: The impact of heat waves on mortality and health inequalities is well documented. Very few studies have assessed the effectiveness of heat action plans (HAPs) on health, and none has used quasi-experimental methods to estimate causal effects of such programs. Objectives: We developed a quasi-experimental method to estimate the causal effects associated with HAPs that allows the identification of heterogeneity across subpopulations, and to apply this method specifically to the case of the Montreal (Quebec, Canada) HAP. Methods: A difference-in-differences approach was undertaken using Montreal death registry data for the summers of 2000–2007 to assess the effectiveness of the Montreal HAP, implemented in 2004, on mortality. To study equity in the effect of HAP implementation, we assessed whether the program effects were heterogeneous across sex (male vs. female), age (≥ 65 years vs. < 65 years), and neighborhood education levels (first vs. third tertile). We conducted sensitivity analyses to assess the validity of the estimated causal effect of the HAP program. Results: We found evidence that the HAP contributed to reducing mortality on hot days, and that the mortality reduction attributable to the program was greater for elderly people and people living in low-education neighborhoods. Conclusion: These findings show promise for programs aimed at reducing the impact of extreme temperatures and health inequities. We propose a new quasi-experimental approach that can be easily applied to evaluate the impact of any program or intervention triggered when daily thresholds are reached. Citation: Benmarhnia T, Bailey Z, Kaiser D, Auger N, King N, Kaufman J. 2016. A difference-in-differences approach to assess the effect of a heat action plan on heat-related mortality, and differences in effectiveness according to sex, age, and socioeconomic status (Montreal, Quebec). Environ Health Perspect 124:1694–1699; http://dx.doi.org/10.1289/EHP203 PMID:27203433

  14. Supergravity actions with integral forms

    NASA Astrophysics Data System (ADS)

    Castellani, L.; Catenacci, R.; Grassi, P. A.

    2014-12-01

    Integral forms provide a natural and powerful tool for the construction of supergravity actions. They are generalizations of usual differential forms and are needed for a consistent theory of integration on supermanifolds. The group geometrical approach to supergravity and its variational principle are reformulated and clarified in this language. Central in our analysis is the Poincaré dual of a bosonic manifold embedded into a supermanifold. Finally, using integral forms we provide a proof of Gates' so-called "Ectoplasmic Integration Theorem", relating superfield actions to component actions.

  15. WIPP Facility Work Plan for Solid Waste Management Units

    SciTech Connect

    Washington TRU Solutions LLC

    2001-02-25

    This 2001 Facility Work Plan (FWP) has been prepared as required by Module VII, Section VII.M.1 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Facility Permit, NM4890139088-TSDF (the Permit); (NMED, 1999a), and incorporates comments from the New Mexico Environment Department (NMED) received on December 6, 2000 (NMED, 2000a). This February 2001 FWP describes the programmatic facility-wide approach to future investigations at Solid Waste Management Units (SWMUs) and Areas of Concern (AOCs) specified in the Permit. The permittees are evaluating data from previous investigations of the SWMUs and AOCs against the newest guidance proposed by the NMED. Based on these data, the permittees expect that no further sampling will be required and that a request for No Further Action (NFA) at the SWMUs and AOCs will be submitted to the NMED. This FWP addresses the current Permit requirements. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI Work Plan and Report sequence with a more flexible decision-making approach. The ACAA process allows a Facility to exit the schedule of compliance contained in the Facility’s Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA process can be entered either before or after an RFI Work Plan. According to the NMED's guidance, a facility can prepare an RFI Work Plan or Sampling and Analysis Plan (SAP) for any SWMU or AOC (NMED, 1998). Based on this guidance, a SAP constitutes an acceptable alternative to the RFI Work Plan specified in the Permit.

  16. Citizen's actions

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The various ways in which energy may be conserved by individual citizens as consumers were explored. The following barriers against citizens implementing an effective conservation program were described: credibility gap between producers and consumers, consumptive lifestyles, inverted rate structure, low fuel costs, and initial costs compared to life cycle costs. The following indices for saving energy were identified: time to develop alternatives, scarcity of fuels, reduction of dependence on imports, and decreasing environmental pollution. The various approaches to encourage energy conservation by individuals were described, followed by specific conclusions and recommendations.

  17. Sex hormone-binding globulin, its membrane receptor, and breast cancer: a new approach to the modulation of estradiol action in neoplastic cells.

    PubMed

    Fortunati, N; Becchis, M; Catalano, M G; Comba, A; Ferrera, P; Raineri, M; Berta, L; Frairia, R

    1999-01-01

    The role of human Sex Hormone-Binding Globulin (SHBG), the plasma carrier of sex steroids, and its membrane receptor, SHBG-R, in estrogen-dependent breast cancer has been investigated in our laboratory in the past few years. SHBG-R is expressed in MCF-10 A cells (not neoplastic mammary cells), MCF-7 cells (breast cancer, ER positive) and in tissue samples from patients affected with ER positive breast cancer, but not in estrogen-insensitive MDA-MB 231 cells. The SHBG/SHBG-R interaction, followed by the binding of estradiol to the complex protein/receptor, causes a significant increase of the intracellular levels of cAMP, but does not modify the amount of estradiol entering MCF-7 cells. The estradiol-induced proliferation of MCF-7 cells is inhibited by SHBG, through SHBG-R, cAMP and PKA. Similarly, the proliferation rate of tissue samples positive for SHBG-R was significantly lower than the proliferation rate of negative samples. SHBG and SHBG-R could thus trigger a 'biologic' anti-estrogenic pathway. In order to get a more detailed knowledge of this system, we first examined the frequence of the reported mutated form of SHBG in 255 breast cancer patients. The mutated SHBG is characterized by a point mutation (Asp 327 --> Asn) causing an additional N-glycosylation site, which does not affect the binding of steroids to SHBG. The frequence of the mutation was significantly higher (24.5%) in estrogen-dependent breast cancers than in healthy control subjects (11.6%). This observation confirms the close relationship between SHBG and estrogen-dependent breast cancer and suggests that the mutation could modify SHBG activity at cell site. Lastly, the possibility of using SHBG to modulate the estradiol action in breast cancer was further studied by transfecting MCF-7 cells with an expression vector carrying the SHBG cDNA (study in collaboration with G.L. Hammond). Transfected cells are able to produce significant amount of SHBG in their medium, but their SHBG-R is reduced to

  18. Mode-of-Action Uncertainty for Dual-Mode Carcinogens: A Bounding Approach for Naphthalene-Induced Nasal Tumors in Rats Based on PBPK and 2-Stage Stochastic Cancer Risk Models

    SciTech Connect

    Bogen, K T

    2007-05-11

    A relatively simple, quantitative approach is proposed to address a specific, important gap in the appr approach recommended by the USEPA Guidelines for Cancer Risk Assessment to oach address uncertainty in carcinogenic mode of action of certain chemicals when risk is extrapolated from bioassay data. These Guidelines recognize that some chemical carcinogens may have a site-specific mode of action (MOA) that is dual, involving mutation in addition to cell-killing induced hyperplasia. Although genotoxicity may contribute to increased risk at all doses, the Guidelines imply that for dual MOA (DMOA) carcinogens, judgment be used to compare and assess results obtained using separate 'linear' (genotoxic) vs. 'nonlinear' (nongenotoxic) approaches to low low-level risk extrapolation. However, the Guidelines allow the latter approach to be used only when evidence is sufficient t to parameterize a biologically based model that reliably o extrapolates risk to low levels of concern. The Guidelines thus effectively prevent MOA uncertainty from being characterized and addressed when data are insufficient to parameterize such a model, but otherwise clearly support a DMOA. A bounding factor approach - similar to that used in reference dose procedures for classic toxicity endpoints - can address MOA uncertainty in a way that avoids explicit modeling of low low-dose risk as a function of administere administered or internal dose. Even when a 'nonlinear' toxicokinetic model cannot be fully validated, implications of DMOA uncertainty on low low-dose risk may be bounded with reasonable confidence when target tumor types happen to be extremely rare. This concept was i illustrated llustrated for a likely DMOA rodent carcinogen naphthalene, specifically to the issue of risk extrapolation from bioassay data on naphthalene naphthalene-induced nasal tumors in rats. Bioassay data, supplemental toxicokinetic data, and related physiologically based p pharmacokinetic and 2 harmacokinetic 2-stage

  19. Action simulation: time course and representational mechanisms

    PubMed Central

    Springer, Anne; Parkinson, Jim; Prinz, Wolfgang

    2013-01-01

    The notion of action simulation refers to the ability to re-enact foreign actions (i.e., actions observed in other individuals). Simulating others' actions implies a mirroring of their activities, based on one's own sensorimotor competencies. Here, we discuss theoretical and experimental approaches to action simulation and the study of its representational underpinnings. One focus of our discussion is on the timing of internal simulation and its relation to the timing of external action, and a paradigm that requires participants to predict the future course of actions that are temporarily occluded from view. We address transitions between perceptual mechanisms (referring to action representation before and after occlusion) and simulation mechanisms (referring to action representation during occlusion). Findings suggest that action simulation runs in real-time; acting on newly created action representations rather than relying on continuous visual extrapolations. A further focus of our discussion pertains to the functional characteristics of the mechanisms involved in predicting other people's actions. We propose that two processes are engaged, dynamic updating and static matching, which may draw on both semantic and motor information. In a concluding section, we discuss these findings in the context of broader theoretical issues related to action and event representation, arguing that a detailed functional analysis of action simulation in cognitive, neural, and computational terms may help to further advance our understanding of action cognition and motor control. PMID:23847563

  20. The President`s Floodplan Management Action Plan: Formulating a watershed and ecosystem approach to flood hazard mitigation and resource protection

    SciTech Connect

    McShane, J.

    1995-12-01

    The Great Midwest Flood of 1993 focused the attention of the Nation on the human and environmental costs associated with decades of efforts to control flooding, unwise land-use decisions, and the loss and degradation of the natural resources and functions of floodplains. The disaster can also be attributed to the single purpose decision-making process and fragmented planning at all levels of government, inconsistent statutory madates, and conflicting jurisdictional responsibilities. The Executive Office of the President established a Floodplain Management Review Committee to determine the major causes and consequences of the flood and to evaluate the performance of existing floodplain management and related watershed programs. The report, Sharing the Challenge: Floodplain Management into the 21st Century, included 90 recommendations to improve floodplain management and water resources planning including the need for a more comprehensive, coordinated approach to floodplain and watershed management. Preparation of the 1994 document A Unified National Program for Floodplain Management commenced prior to the Midwest Flood of 1993 and was completed, coincidentally, concurrently with the Review Committee`s report Sharing the Challenge. Both reports urge the formulation of a more comprehensive, watershed approach to managing human activities and protecting natural systems to ensure the long term viability of riparian ecosystems and the sustainable development of riverine communities. Both reports recognize that effective floodplain management will reduce the financial burdens placed upon all levels of government to compensate property owners and governments for flood losses caused by unwise land use decisions by individuals, as well as governments. This paper focuses on the fundamental changes in Federal floodplain management policies and programs that are emerging that will affect how as a Nation manage and use our floodplain resources into the 21st Century.

  1. mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence.

    PubMed

    Finnigan, Gregory C; Thorner, Jeremy

    2016-07-07

    Genome editing exploiting CRISPR/Cas9 has been adopted widely in academia and in the biotechnology industry to manipulate DNA sequences in diverse organisms. Molecular engineering of Cas9 itself and its guide RNA, and the strategies for using them, have increased efficiency, optimized specificity, reduced inappropriate off-target effects, and introduced modifications for performing other functions (transcriptional regulation, high-resolution imaging, protein recruitment, and high-throughput screening). Moreover, Cas9 has the ability to multiplex, i.e., to act at different genomic targets within the same nucleus. Currently, however, introducing concurrent changes at multiple loci involves: (i) identification of appropriate genomic sites, especially the availability of suitable PAM sequences; (ii) the design, construction, and expression of multiple sgRNA directed against those sites; (iii) potential difficulties in altering essential genes; and (iv) lingering concerns about "off-target" effects. We have devised a new approach that circumvents these drawbacks, as we demonstrate here using the yeast Saccharomyces cerevisiae First, any gene(s) of interest are flanked upstream and downstream with a single unique target sequence that does not normally exist in the genome. Thereafter, expression of one sgRNA and cotransformation with appropriate PCR fragments permits concomitant Cas9-mediated alteration of multiple genes (both essential and nonessential). The system we developed also allows for maintenance of the integrated, inducible Cas9-expression cassette or its simultaneous scarless excision. Our scheme-dubbed mCAL for " M: ultiplexing of C: as9 at A: rtificial L: oci"-can be applied to any organism in which the CRISPR/Cas9 methodology is currently being utilized. In principle, it can be applied to install synthetic sequences into the genome, to generate genomic libraries, and to program strains or cell lines so that they can be conveniently (and repeatedly

  2. mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence

    PubMed Central

    Finnigan, Gregory C.; Thorner, Jeremy

    2016-01-01

    Genome editing exploiting CRISPR/Cas9 has been adopted widely in academia and in the biotechnology industry to manipulate DNA sequences in diverse organisms. Molecular engineering of Cas9 itself and its guide RNA, and the strategies for using them, have increased efficiency, optimized specificity, reduced inappropriate off-target effects, and introduced modifications for performing other functions (transcriptional regulation, high-resolution imaging, protein recruitment, and high-throughput screening). Moreover, Cas9 has the ability to multiplex, i.e., to act at different genomic targets within the same nucleus. Currently, however, introducing concurrent changes at multiple loci involves: (i) identification of appropriate genomic sites, especially the availability of suitable PAM sequences; (ii) the design, construction, and expression of multiple sgRNA directed against those sites; (iii) potential difficulties in altering essential genes; and (iv) lingering concerns about “off-target” effects. We have devised a new approach that circumvents these drawbacks, as we demonstrate here using the yeast Saccharomyces cerevisiae. First, any gene(s) of interest are flanked upstream and downstream with a single unique target sequence that does not normally exist in the genome. Thereafter, expression of one sgRNA and cotransformation with appropriate PCR fragments permits concomitant Cas9-mediated alteration of multiple genes (both essential and nonessential). The system we developed also allows for maintenance of the integrated, inducible Cas9-expression cassette or its simultaneous scarless excision. Our scheme—dubbed mCAL for “Multiplexing of Cas9 at Artificial Loci”—can be applied to any organism in which the CRISPR/Cas9 methodology is currently being utilized. In principle, it can be applied to install synthetic sequences into the genome, to generate genomic libraries, and to program strains or cell lines so that they can be conveniently (and repeatedly

  3. Action Learning Research? Reflections from the Colloquium at the Third International Conference on Action Learning

    ERIC Educational Resources Information Center

    Coghlan, David

    2013-01-01

    The case for the notion of action learning research has been posed and explored in several publications over the past few years. There is no tradition within action learning of understanding it as an approach to research. Within some academic circles, there has been a focus on the "action turn," the development of the notion of actionable…

  4. Its All Action, Its All Learning: Action Learning in SMEs

    ERIC Educational Resources Information Center

    Clarke, Jean; Thorpe, Richard; Anderson, Lisa; Gold, Jeff

    2006-01-01

    Purpose: The purpose of this paper is to argue that action learning (AL) may provide a means of successfully developing small to medium-sized enterprises (SMEs). Design/methodology/approach: The literature around SME learning suggests a number of processes are important for SME learning which similarity, it is argued, are encompassed in AL. AL may…

  5. Talent Management: Emphasis on Action

    ERIC Educational Resources Information Center

    Butterfield, Barbara

    2008-01-01

    Recent discussions among HR practitioners in higher education have focused on talent management; specifically, the concept of developing a college or university talent management approach balanced between planning and action. Talent management as a planning tool looks very similar to workforce planning, but where HR will experience a real…

  6. Object-Driven and Temporal Action Rules Mining

    ERIC Educational Resources Information Center

    Hajja, Ayman

    2013-01-01

    In this thesis, I present my complete research work in the field of action rules, more precisely object-driven and temporal action rules. The drive behind the introduction of object-driven and temporally based action rules is to bring forth an adapted approach to extract action rules from a subclass of systems that have a specific nature, in which…

  7. Participatory Action Research (PAR) cum Action Research (AR) in Teacher Professional Development: A Literature Review

    ERIC Educational Resources Information Center

    Morales, Marie Paz E.

    2016-01-01

    This paper reviews Participatory Action Research as an approach to teacher professional development. It maps the origins of Participatory Action Research (PAR) and discusses the benefits and challenges that have been identified by other researchers in utilizing PAR approaches in conducting research. It draws ideas of combining the features of…

  8. WIPP Facility Work Plan for Solid Waste Management Units and Areas of Concern

    SciTech Connect

    Washington TRU Solutions LLC

    2002-03-05

    his 2002 Facility Work Plan (FWP) has been prepared as required by Module VII,Permit Condition VII.U.3 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Facility Permit, NM4890139088-TSDF (the Permit) (New Mexico Environment Department [NMED], 1999a), and incorporates comments from the NMED received onDecember 6, 2000 (NMED, 2000a). This February 2002 FWP describes the program-matic facility-wide approach to future investigations at Solid Waste Management Units (SWMU) and Areas of Concern (AOC) specified in the Permit. The Permittees are evaluating data from previous investigations of the SWMUs and AOCs against the mostrecent guidance proposed by the NMED. Based on these data, and completion of the August 2001 sampling requested by the NMED, the Permittees expect that no further sampling will be required and that a request for No Further Action (NFA) at the SWMUs and AOCs will be submitted to the NMED. This FWP addresses the current Permit requirements. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the Resource Conservation and Recovery Act (RCRA)Facility Investigation (RFI) specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may beused for any SWMU or AOC (NMED, 1998). This accelerated approach is used toreplace the standard RFI Work Plan and Report sequence with a more flexible decision-making approach. The ACAA process allows a facility to exit the schedule of compliance contained in the facility's Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA process can be entered either before or after an RFI Work Plan. According to the NMED's guidance, a facility can prepare an RFI Work Plan or Sampling and Analysis Plan (SAP) for any SWMU or AOC (NMED, 1998). Based on this guidance, a SAP constitutes an acceptable alternative to

  9. WIPP Facility Work Plan for Solid Waste Management Units

    SciTech Connect

    Washington TRU Solutions LLC

    2002-02-14

    This 2002 Facility Work Plan (FWP) has been prepared as required by Module VII, Permit Condition VII.U.3 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Facility Permit, NM4890139088-TSDF (the Permit) (New Mexico Environment Department [NMED], 1999a), and incorporates comments from the NMED received on December 6, 2000 (NMED, 2000a). This February 2002 FWP describes the programmatic facility-wide approach to future investigations at Solid Waste Management Units (SWMU) and Areas of Concern (AOC) specified in the Permit. The Permittees are evaluating data from previous investigations of the SWMUs and AOCs against the most recent guidance proposed by the NMED. Based on these data, and completion of the August 2001 sampling requested by the NMED, the Permittees expect that no further sampling will be required and that a request for No Further Action (NFA) at the SWMUs and AOCs will be submitted to the NMED. This FWP addresses the current Permit requirements. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI Work Plan and Report sequence with a more flexible decision-making approach. The ACAA process allows a facility to exit the schedule of compliance contained in the facility's Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA processcan be entered either before or after an RFI Work Plan. According to the NMED's guidance, a facility can prepare an RFI Work Plan or Sampling and Analysis Plan (SAP) for any SWMU or AOC (NMED, 1998). Based on this guidance, a SAP constitutes an acceptable

  10. WIPP Facility Work Plan for Solid Waste Management Units and Areas of Concern

    SciTech Connect

    Washington TRU Solutions LLC

    2002-03-05

    This 2002 Facility Work Plan (FWP) has been prepared as required by Module VII, Permit Condition VII.U.3 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Facility Permit, NM4890139088-TSDF (the Permit) (New Mexico Environment Department [NMED], 1999a), and incorporates comments from the NMED received on December 6, 2000 (NMED, 2000a). This February 2002 FWP describes the programmatic facility-wide approach to future investigations at Solid Waste Management Units (SWMU) and Areas of Concern (AOC) specified in the Permit. The Permittees are evaluating data from previous investigations of the SWMUs and AOCs against the most recent guidance proposed by the NMED. Based on these data, and completion of the August 2001 sampling requested by the NMED, the Permittees expect that no further sampling will be required and that a request for No Further Action (NFA) at the SWMUs and AOCs will be submitted to the NMED. This FWP addresses the current Permit requirements. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI Work Plan and Report sequence with a more flexible decision-making approach. The ACAA process allows a facility to exit the schedule of compliance contained in the facility's Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA processcan be entered either before or after an RFI Work Plan. According to the NMED's guidance, a facility can prepare an RFI Work Plan or Sampling and Analysis Plan (SAP) for any SWMU or AOC (NMED, 1998). Based on this guidance, a SAP constitutes an acceptable

  11. Protective Action Guides (PAGs)

    EPA Pesticide Factsheets

    The Protective Action Guide (PAG) manual contains radiation dose guidelines that would trigger public safety measures. EPA developed Protective Action Guides to help responders plan for radiation emergencies.

  12. Implementing a Tactical Approach through Action Research

    ERIC Educational Resources Information Center

    Gubacs-Collins, Klara

    2007-01-01

    Background: Influenced by the original observations of Bunker and Thorpe, physical education theorists began to question the effectiveness of a traditional model for teaching games and have increasingly begun to believe that concentrating only on specific motor responses (techniques) fails to take into account the contextual nature of games. Games…

  13. Habits, action sequences, and reinforcement learning

    PubMed Central

    Dezfouli, Amir; Balleine, Bernard W.

    2012-01-01

    It is now widely accepted that instrumental actions can be either goal-directed or habitual; whereas the former are rapidly acquire and regulated by their outcome, the latter are reflexive, elicited by antecedent stimuli rather than their consequences. Model-based reinforcement learning (RL) provides an elegant description of goal-directed action. Through exposure to states, actions and rewards, the agent rapidly constructs a model of the world and can choose an appropriate action based on quite abstract changes in environmental and evaluative demands. This model is powerful but has a problem explaining the development of habitual actions. To account for habits, theorists have argued that another action controller is required, called model-free RL, that does not form a model of the world but rather caches action values within states allowing a state to select an action based on its reward history rather than its consequences. Nevertheless, there are persistent problems with important predictions from the model; most notably the failure of model-free RL correctly to predict the insensitivity of habitual actions to changes in the action-reward contingency. Here, we suggest that introducing model-free RL in instrumental conditioning is unnecessary and demonstrate that reconceptualizing habits as action sequences allows model-based RL to be applied to both goal-directed and habitual actions in a manner consistent with what real animals do. This approach has significant implications for the way habits are currently investigated and generates new experimental predictions. PMID:22487034

  14. Habits, action sequences and reinforcement learning.

    PubMed

    Dezfouli, Amir; Balleine, Bernard W

    2012-04-01

    It is now widely accepted that instrumental actions can be either goal-directed or habitual; whereas the former are rapidly acquired and regulated by their outcome, the latter are reflexive, elicited by antecedent stimuli rather than their consequences. Model-based reinforcement learning (RL) provides an elegant description of goal-directed action. Through exposure to states, actions and rewards, the agent rapidly constructs a model of the world and can choose an appropriate action based on quite abstract changes in environmental and evaluative demands. This model is powerful but has a problem explaining the development of habitual actions. To account for habits, theorists have argued that another action controller is required, called model-free RL, that does not form a model of the world but rather caches action values within states allowing a state to select an action based on its reward history rather than its consequences. Nevertheless, there are persistent problems with important predictions from the model; most notably the failure of model-free RL correctly to predict the insensitivity of habitual actions to changes in the action-reward contingency. Here, we suggest that introducing model-free RL in instrumental conditioning is unnecessary, and demonstrate that reconceptualizing habits as action sequences allows model-based RL to be applied to both goal-directed and habitual actions in a manner consistent with what real animals do. This approach has significant implications for the way habits are currently investigated and generates new experimental predictions.

  15. Exploring and Implementing Participatory Action Synthesis

    ERIC Educational Resources Information Center

    Wimpenny, Katherine; Savin-Baden, Maggi

    2012-01-01

    This article presents participatory action synthesis as a new approach to qualitative synthesis which may be used to facilitate the promotion and use of qualitative research for policy and practice. The authors begin by outlining different forms of qualitative research synthesis and then present participatory action synthesis, a collaborative…

  16. 7 CFR 372.5 - Classification of actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES § 372.5 Classification of actions. (a) Actions normally requiring environmental impact statements. This class of policymakings and rulemakings seeks to establish programmatic approaches to animal and plant health...

  17. Action Research: Rethinking Lewin.

    ERIC Educational Resources Information Center

    Dickens, Linda; Watkins, Karen

    1999-01-01

    Explores both historical and contemporary definitions of action research. Describes the process and goals of action research in the tradition of Lewin. Presents a case study of an action-research project involving two teams in a high-technology corporation that depicts the process in action. (Author/CCM)

  18. Inferences about Action Engage Action Systems

    ERIC Educational Resources Information Center

    Taylor, Lawrence J.; Lev-Ari, Shiri; Zwaan, Rolf A.

    2008-01-01

    Verbal descriptions of actions activate compatible motor responses [Glenberg, A. M., & Kaschak, M. P. (2002). Grounding language in action. "Psychonomic Bulletin & Review, 9", 558-565]. Previous studies have found that the motor processes for manual rotation are engaged in a direction-specific manner when a verb disambiguates the direction of…

  19. Lehrerbelastungsforschung -- Erweiterung durch ein handlungpsychologisches Belastungskonzept (Research on Teacher's Ability To Cope with Stress -- A Broadening of the Approach by Including a Psychology of Action-Concept of Stress).

    ERIC Educational Resources Information Center

    Krause, Andreas

    2003-01-01

    Reveals that most research on teacher stress relies on personal accounts. Presents a psychology of action-concept of stress and that has been transferred to teacher's instructional activities. Argues that this psychology of action concept of stress helps develop an understanding of teachers' work and what may lead to psychological stress. (CAJ)

  20. Lawrence Berkeley Laboratory Affirmative Action Program. Revised

    SciTech Connect

    1995-06-01

    The Lawrence Berkeley Laboratory`s Affirmative Action Program (AAP) serves as a working document that describes current policies, practices, and results in the area of affirmative action. It represents the Laboratory`s framework for an affirmative approach to increasing the representation of people of color and women in segments of our work force where they have been underrepresented and taking action to increase the employment of persons with disabilities and special disabled and Vietnam era veterans. The AAP describes the hierarchy of responsibility for Laboratory affirmative action, the mechanisms that exist for full Laboratory participation in the AAP, the policies and procedures governing recruitment at all levels, the Laboratory`s plan for monitoring, reporting, and evaluating affirmative action progress, and a description of special affirmative action programs and plans the Laboratory has used and will use in its efforts to increase the representation and retention of groups historically underrepresented in our work force.

  1. Set Goals & Select Actions

    EPA Pesticide Factsheets

    This phase of the Local Climate Action Framework will help users articulate the goals for their climate, energy, and sustainability programs, as well as to identify the actions that are most appropriate to help meet those goals.

  2. American Lead Action Memorandum

    EPA Pesticide Factsheets

    ACTION MEMORANDUM— Request for a Time-Critical Removal Action andExemption from the $2 Million and 12-Month Statutory Limits at the AmericanLead Site, Indianapolis, Marion County, Indiana (Site ID #B56J)

  3. An approach to identify SNPs in the gene encoding acetyl-CoA acetyltransferase-2 (ACAT-2) and their proposed role in metabolic processes in pig.

    PubMed

    Sodhi, Simrinder Singh; Ghosh, Mrinmoy; Song, Ki Duk; Sharma, Neelesh; Kim, Jeong Hyun; Kim, Nam Eun; Lee, Sung Jin; Kang, Chul Woong; Oh, Sung Jong; Jeong, Dong Kee

    2014-01-01

    The novel liver protein acetyl-CoA acetyltransferase-2 (ACAT2) is involved in the beta-oxidation and lipid metabolism. Its comprehensive relative expression, in silico non-synonymous single nucleotide polymorphism (nsSNP) analysis, as well as its annotation in terms of metabolic process with another protein from the same family, namely, acetyl-CoA acyltransferase-2 (ACAA2) was performed in Sus scrofa. This investigation was conducted to understand the most important nsSNPs of ACAT2 in terms of their effects on metabolic activities and protein conformation. The two most deleterious mutations at residues 122 (I to V) and 281 (R to H) were found in ACAT2. Validation of expression of genes in the laboratory also supported the idea of differential expression of ACAT2 and ACAA2 conceived through the in silico analysis. Analysis of the relative expression of ACAT2 and ACAA2 in the liver tissue of Jeju native pig showed that the former expressed significantly higher (P<0.05). Overall, the computational prediction supported by wet laboratory analysis suggests that ACAT2 might contribute more to metabolic processes than ACAA2 in swine. Further associations of SNPs in ACAT2 with production traits might guide efforts to improve growth performance in Jeju native pigs.

  4. Action in Development

    ERIC Educational Resources Information Center

    von Hofsten, Claes

    2007-01-01

    It is argued that cognitive development has to be understood in the functional perspective provided by actions. Actions reflect all aspects of cognitive development including the motives of the child, the problems to be solved, and the constraints and possibilities of the child's body and sensorimotor system. Actions are directed into the future…

  5. Action Learning at Work.

    ERIC Educational Resources Information Center

    Mumford, Alan, Ed.

    This book contains 34 papers examining the theory, process, and outcomes of action learning at work. The following papers are included: "An Introduction to the Text" (Alan Mumford); "The Learning Equation" (Reg Revans); "Action Learning as a Vehicle for Learning" (Alan Mumford); "Placing Action Learning and…

  6. Conservation Action Handbook.

    ERIC Educational Resources Information Center

    National Rifle Association, Washington, DC.

    Conservation problems are identified, with some suggestions for action. General areas covered are: Wildlife Conservation, Soil Conservation, Clean Water, Air Pollution Action, and Outdoor Recreation Action. Appendices list private organizations or agencies concerned with natural resource use and/or management, congressional committees considering…

  7. Planning as Action Research

    ERIC Educational Resources Information Center

    de Gonzalez, Carmen Beatriz; Hernandez, Teresa; Kusch, Jim; Ryan, Charly

    2004-01-01

    Planning contains so much more than the written plan. Early in 2000, an invitation came from the Collaborative Action Research Network (CARN), to people experienced in action research who might want to help plan and present an action research event for elementary school science teachers in Venezuela, South America, in Autumn 2000. This article…

  8. Participatory Action Research.

    ERIC Educational Resources Information Center

    Walker, Martha Lentz

    1993-01-01

    Describes aspects of participatory action research and considers advantages of using participatory action research in research by disabilities and rehabilitation researchers. Notes that participatory action research can be built into any rehabilitation research design but that it rests upon the recognition of persons with disabilities as integral…

  9. Issues in Teaching Participatory Action Research.

    ERIC Educational Resources Information Center

    McNicoll, Paule

    1999-01-01

    Discusses participatory action research, a methodology incorporating subjects in the research and indexing results to transformation in the lives of those involved. The approach is gaining momentum and recognition in academic circles but is often limited to specialized training centers. Two years of experience teaching this approach in social work…

  10. Participatory Action Research and Public Policy.

    ERIC Educational Resources Information Center

    Turnbull, H. Rutherford, III; Turnbull, Ann P.

    This paper describes collegial model approaches to the interactions between rehabilitation researchers and individuals with disabilities or their family members. The approaches, called participatory research and participatory action research, grew out of a 1989 conference sponsored by the National Institute on Disability and Rehabilitation…

  11. The Dynamics of Perception and Action

    ERIC Educational Resources Information Center

    Warren, William H.

    2006-01-01

    How might one account for the organization in behavior without attributing it to an internal control structure? The present article develops a theoretical framework called behavioral dynamics that integrates an information-based approach to perception with a dynamical systems approach to action. For a given task, the agent and its environment are…

  12. Using Action Research and Action Learning for Entrepreneurial Network Capability Development

    ERIC Educational Resources Information Center

    McGrath, Helen; O'Toole, Thomas

    2016-01-01

    This paper applies an action research (AR) design and action learning (AL) approach to network capability development in an entrepreneurial context. Recent research suggests that networks are a viable strategy for the entrepreneurial firm to overcome the liabilities associated with newness and smallness. However, a gap emerges as few, if any,…

  13. Practicing What We Teach: Using Action Research to Learn about Teaching Action Research

    ERIC Educational Resources Information Center

    Brown, Barb; Dressler, Roswita; Eaton, Sarah Elaine; Jacobsen, Michele

    2015-01-01

    In this article, action research is explored as a process for instructor reflection, professional learning and collaboration. The context for the professional learning was the teaching of graduate level education courses in which action research, in conjunction with a cohort-based, collaboratory approach to learning, was used to facilitate…

  14. From muscles synergies and individual goals to interpersonal synergies and shared goals: Mirror neurons and interpersonal action hierarchies. Comment on "Grasping synergies: A motor-control approach to the mirror neuron mechanism" by D'Ausilio et al.

    NASA Astrophysics Data System (ADS)

    Candidi, Matteo; Sacheli, Lucia Maria; Aglioti, Salvatore Maria

    2015-03-01

    D'Ausilio et al. [28] must be praised for bringing attention to the important question of how human Mirror Neurons (MNs) may contribute to action perception, prediction and understanding [1] and for linking their role with the granularity of the motor system as conceptualized in the domain of action control theories. Although we think that the Authors are right in saying that the granularity of the motor system constrains the granularity of the MN system, we speculate that the contribution of MNs to action perception, prediction and understanding is also constrained by the connections between MNs and other cortical and subcortical regions, and by the identity of MNs, i.e. whether they are interneurons or pyramidal cells [2]. In other words, the functional contribution of MS depends on whether they are connected to sensory, emotional and cognitive networks for the service of action perception, prediction and understanding.

  15. Contextual Action Theory in Career Counselling: Some Misunderstood Issues.

    ERIC Educational Resources Information Center

    Valach, Ladislav; Young, Richard A.

    2002-01-01

    Current discussion of action theory is premised on the fact that many counselors may avoid action approaches because of previous misunderstandings. Article addresses 12 misunderstandings. Overall, action theory is presented as highly suitable for understanding human behavior and for counseling as it is based on a wide spectrum of research as well…

  16. National Biofuels Action Plan

    DTIC Science & Technology

    2008-10-01

    Leading the Federal Interagency Biomass Research and Development Initiative October 2008 National Biofuels Action Plan Biomass Research and...REPORT DATE OCT 2008 2. REPORT TYPE 3. DATES COVERED 00-00-2008 to 00-00-2008 4. TITLE AND SUBTITLE National Biofuels Action Plan 5a. CONTRACT...goal of the National Biofuels Action Plan is to maximize the environmental and economic benefi ts of biofuels use by advancing sustainable practices

  17. Stereoscopically Observing Manipulative Actions

    PubMed Central

    Ferri, S.; Pauwels, K.; Rizzolatti, G.; Orban, G. A.

    2016-01-01

    The purpose of this study was to investigate the contribution of stereopsis to the processing of observed manipulative actions. To this end, we first combined the factors “stimulus type” (action, static control, and dynamic control), “stereopsis” (present, absent) and “viewpoint” (frontal, lateral) into a single design. Four sites in premotor, retro-insular (2) and parietal cortex operated specifically when actions were viewed stereoscopically and frontally. A second experiment clarified that the stereo-action-specific regions were driven by actions moving out of the frontoparallel plane, an effect amplified by frontal viewing in premotor cortex. Analysis of single voxels and their discriminatory power showed that the representation of action in the stereo-action-specific areas was more accurate when stereopsis was active. Further analyses showed that the 4 stereo-action-specific sites form a closed network converging onto the premotor node, which connects to parietal and occipitotemporal regions outside the network. Several of the specific sites are known to process vestibular signals, suggesting that the network combines observed actions in peripersonal space with gravitational signals. These findings have wider implications for the function of premotor cortex and the role of stereopsis in human behavior. PMID:27252350

  18. Action principles in nature

    NASA Astrophysics Data System (ADS)

    Barrow, John D.; Tipler, Frank J.

    1988-01-01

    Physical theories have their most fundamental expression as action integrals. This suggests that the total action of the universe is the most fundamental physical quantity, and hence finite. In this article it is argued that finite universal action implies that the universe is spatially closed. Further, the possible spatial topologies, the types of matter that can dominate the early universe dynamics, and the form of any quadratic additions to the lagrangian of general relativity are constrained. Initial and final cosmological curvature singularities are required to avoid a universal action singularity.

  19. Action-based effects on music perception.

    PubMed

    Maes, Pieter-Jan; Leman, Marc; Palmer, Caroline; Wanderley, Marcelo M

    2014-01-03

    The classical, disembodied approach to music cognition conceptualizes action and perception as separate, peripheral processes. In contrast, embodied accounts of music cognition emphasize the central role of the close coupling of action and perception. It is a commonly established fact that perception spurs action tendencies. We present a theoretical framework that captures the ways in which the human motor system and its actions can reciprocally influence the perception of music. The cornerstone of this framework is the common coding theory, postulating a representational overlap in the brain between the planning, the execution, and the perception of movement. The integration of action and perception in so-called internal models is explained as a result of associative learning processes. Characteristic of internal models is that they allow intended or perceived sensory states to be transferred into corresponding motor commands (inverse modeling), and vice versa, to predict the sensory outcomes of planned actions (forward modeling). Embodied accounts typically refer to inverse modeling to explain action effects on music perception (Leman, 2007). We extend this account by pinpointing forward modeling as an alternative mechanism by which action can modulate perception. We provide an extensive overview of recent empirical evidence in support of this idea. Additionally, we demonstrate that motor dysfunctions can cause perceptual disabilities, supporting the main idea of the paper that the human motor system plays a functional role in auditory perception. The finding that music perception is shaped by the human motor system and its actions suggests that the musical mind is highly embodied. However, we advocate for a more radical approach to embodied (music) cognition in the sense that it needs to be considered as a dynamical process, in which aspects of action, perception, introspection, and social interaction are of crucial importance.

  20. Action-based effects on music perception

    PubMed Central

    Maes, Pieter-Jan; Leman, Marc; Palmer, Caroline; Wanderley, Marcelo M.

    2013-01-01

    The classical, disembodied approach to music cognition conceptualizes action and perception as separate, peripheral processes. In contrast, embodied accounts of music cognition emphasize the central role of the close coupling of action and perception. It is a commonly established fact that perception spurs action tendencies. We present a theoretical framework that captures the ways in which the human motor system and its actions can reciprocally influence the perception of music. The cornerstone of this framework is the common coding theory, postulating a representational overlap in the brain between the planning, the execution, and the perception of movement. The integration of action and perception in so-called internal models is explained as a result of associative learning processes. Characteristic of internal models is that they allow intended or perceived sensory states to be transferred into corresponding motor commands (inverse modeling), and vice versa, to predict the sensory outcomes of planned actions (forward modeling). Embodied accounts typically refer to inverse modeling to explain action effects on music perception (Leman, 2007). We extend this account by pinpointing forward modeling as an alternative mechanism by which action can modulate perception. We provide an extensive overview of recent empirical evidence in support of this idea. Additionally, we demonstrate that motor dysfunctions can cause perceptual disabilities, supporting the main idea of the paper that the human motor system plays a functional role in auditory perception. The finding that music perception is shaped by the human motor system and its actions suggests that the musical mind is highly embodied. However, we advocate for a more radical approach to embodied (music) cognition in the sense that it needs to be considered as a dynamical process, in which aspects of action, perception, introspection, and social interaction are of crucial importance. PMID:24454299

  1. Action Learning in China

    ERIC Educational Resources Information Center

    Marquardt, Michael J.

    2015-01-01

    Action learning was introduced into China less than 20 years ago, but has rapidly become a valuable tool for organizations seeking to solve problems, develop their leaders, and become learning organizations. This article provides an historical overview of action learning in China, its cultural underpinnings, and five case studies. It concludes…

  2. Who Needs Affirmative Action.

    ERIC Educational Resources Information Center

    Ginger, Ann Fagan

    1979-01-01

    Affirmative action and reverse discrimination are discussed. Facts that were omitted from the court record on the Bakke case are examined. The need for encouraging minority students and women to continue to press for school admission and for lawyers to continue to press affirmative action suits is stressed. (MC)

  3. Renormalized action improvements

    SciTech Connect

    Zachos, C.

    1984-01-01

    Finite lattice spacing artifacts are suppressed on the renormalized actions. The renormalized action trajectories of SU(N) lattice gauge theories are considered from the standpoint of the Migdal-Kadanoff approximation. The minor renormalized trajectories which involve representations invariant under the center are discussed and quantified. 17 references.

  4. Training for Nonviolent Action.

    ERIC Educational Resources Information Center

    Olson, Theodore W.; Shivers, Lynne

    The theory and practice of nonviolent action training as it exists to date are reviewed in this pamphlet. A response to a renewal of interest in alternative forms of social action, the pamphlet results specifically from an international seminar of experienced organizers and trainers held at Preston Patrick, Westmorland, England, June 27 - July 2,…

  5. Affirmative Action Program Manual.

    ERIC Educational Resources Information Center

    Ventura County Community Coll. District, CA.

    Guidelines relating to the affirmative action program of the Ventura County Community College District are provided in this manual. Affirmative action is defined as, "A set of specific and result-oriented procedures to which a contractor commits himself/herself to apply every good faith effort. The objective of those procedures, plus such efforts,…

  6. 25 Action Learning Schools.

    ERIC Educational Resources Information Center

    National Association of Secondary School Principals, Reston, VA.

    This booklet on action-learning reflects an interest in preparing youth for the world of real experiences. Arranged in two major parts, the first offers information on the background and development of action-learning. Included in this section are the conclusions of the Panel on Youth of the President's Science Advisory Committee, the National…

  7. Action Learning and Leadership.

    ERIC Educational Resources Information Center

    Marquardt, Michael J.

    2000-01-01

    Today's leaders perform the following roles: systems thinker, change agent, innovator, servant, polychronic coordinator, teacher-mentor, and visionary. The elements of action learning (real problems, teams, reflective inquiry, commitment to action, focus on learning) contribute to the development of these critical skills. (Author/SK)

  8. Handbook for Ecology Action.

    ERIC Educational Resources Information Center

    Eber, Ronald

    This handbook has been compiled to aid concerned individuals and ecology groups more adequately define their goals, initiate good programs, and take effective action. It examines the ways a group of working individuals can become involved in action programs for ecological change. Part 1 deals with organization, preliminary organizing, structuring,…

  9. Semantic pyramids for gender and action recognition.

    PubMed

    Khan, Fahad Shahbaz; van de Weijer, Joost; Anwer, Rao Muhammad; Felsberg, Michael; Gatta, Carlo

    2014-08-01

    Person description is a challenging problem in computer vision. We investigated two major aspects of person description: 1) gender and 2) action recognition in still images. Most state-of-the-art approaches for gender and action recognition rely on the description of a single body part, such as face or full-body. However, relying on a single body part is suboptimal due to significant variations in scale, viewpoint, and pose in real-world images. This paper proposes a semantic pyramid approach for pose normalization. Our approach is fully automatic and based on combining information from full-body, upper-body, and face regions for gender and action recognition in still images. The proposed approach does not require any annotations for upper-body and face of a person. Instead, we rely on pretrained state-of-the-art upper-body and face detectors to automatically extract semantic information of a person. Given multiple bounding boxes from each body part detector, we then propose a simple method to select the best candidate bounding box, which is used for feature extraction. Finally, the extracted features from the full-body, upper-body, and face regions are combined into a single representation for classification. To validate the proposed approach for gender recognition, experiments are performed on three large data sets namely: 1) human attribute; 2) head-shoulder; and 3) proxemics. For action recognition, we perform experiments on four data sets most used for benchmarking action recognition in still images: 1) Sports; 2) Willow; 3) PASCAL VOC 2010; and 4) Stanford-40. Our experiments clearly demonstrate that the proposed approach, despite its simplicity, outperforms state-of-the-art methods for gender and action recognition.

  10. Conscious Vision in Action.

    PubMed

    Briscoe, Robert; Schwenkler, John

    2015-09-01

    It is natural to assume that the fine-grained and highly accurate spatial information present in visual experience is often used to guide our bodily actions. Yet this assumption has been challenged by proponents of the Two Visual Systems Hypothesis (TVSH), according to which visuomotor programming is the responsibility of a "zombie" processing stream whose sources of bottom-up spatial information are entirely non-conscious (Clark, 2007, 2009; Goodale & Milner, 1992, 2004a; Milner & Goodale, 1995/2006, 2008). In many formulations of TVSH, the role of conscious vision in action is limited to "recognizing objects, selecting targets for action, and determining what kinds of action, broadly speaking, to perform" (Clark, 2007, p. 570). Our aim in this study is to show that the available evidence not only fails to support this dichotomous view but actually reveals a significant role for conscious vision in motor programming, especially for actions that require deliberate attention.

  11. Communication (action with communicative content).

    PubMed

    Russo, M T

    2010-01-01

    The term Communication generally designate the transmission of a message of concepts, feelings or needs from a speaker to a receiver by means of verbal or no verbal language. The pragmatic approach to human communication has put in evidence a further implication of this concept: every behaviour therefore has a value even when it is not intentional. Recently, a more dynamic concept of communication has been elaborated where communication means communicative action. This interpretation is the starting point for the theory of the "communicative acting" and subsequently of the so called discourse ethic elaborated by J. Habermas.

  12. Indonesia: persues ICPD Action Programme.

    PubMed

    1999-09-01

    Since the 1994 International Conference on Population and Development (ICPD), the focus of Indonesia's population policies have utilized people- and family-centered approaches, emphasizing poverty alleviation as a central challenge for development initiatives. However, the ongoing economic crisis in the country is hampering its efforts to extend reproductive health services to the people. The crisis also resulted in loss of jobs, price increases, and a drop in the purchasing power of families. Despite these conditions, Indonesia will still pursue its implementation of the ICPD Program of Action, and the international community should help the country achieve the goals of the ICPD amidst the economic crisis.

  13. Accomplishing the Goals of Affirmative Action--with or without Affirmative Action

    ERIC Educational Resources Information Center

    Sternberg, Robert J.

    2005-01-01

    Might it be possible to achieve some or all of the goals of affirmative action through an approach based on an entirely different definition of the problem? This article says "yes." Its logic rests not upon an approach that creates informal quotas for identified groups, but instead on one aimed at discovering merit in people who are…

  14. Topological lattice actions

    NASA Astrophysics Data System (ADS)

    Bietenholz, W.; Gerber, U.; Pepe, M.; Wiese, U.-J.

    2010-12-01

    We consider lattice field theories with topological actions, which are invariant against small deformations of the fields. Some of these actions have infinite barriers separating different topological sectors. Topological actions do not have the correct classical continuum limit and they cannot be treated using perturbation theory, but they still yield the correct quantum continuum limit. To show this, we present analytic studies of the 1-d O(2) and O(3) model, as well as Monte Carlo simulations of the 2-d O(3) model using topological lattice actions. Some topological actions obey and others violate a lattice Schwarz inequality between the action and the topological charge Q. Irrespective of this, in the 2-d O(3) model the topological susceptibility {χ_t} = {{{left< {{Q^2}} rightrangle }} left/ {V} right.} is logarithmically divergent in the continuum limit. Still, at non-zero distance the correlator of the topological charge density has a finite continuum limit which is consistent with analytic predictions. Our study shows explicitly that some classically important features of an action are irrelevant for reaching the correct quantum continuum limit.

  15. Spacelike brane actions.

    PubMed

    Hashimoto, Koji; Ho, Pei-Ming; Wang, John E

    2003-04-11

    We derive effective actions for "spacelike branes" (S-branes) and find a solution describing the formation of fundamental strings in the rolling tachyon background. The S-brane action is a Dirac-Born-Infeld action for Euclidean world volumes defined in the context of time-dependent tachyon condensation of non-BPS (Bogomol'nyi-Prasad-Sommerfield) branes. It includes gauge fields and, in particular, a scalar field associated with translation along the time direction. We show that the BIon spike solutions constructed in this system correspond to the production of a confined electric flux tube (a fundamental string) at late time of the rolling tachyon.

  16. Conscious Control over Action.

    PubMed

    Shepherd, Joshua

    2015-06-01

    The extensive involvement of nonconscious processes in human behaviour has led some to suggest that consciousness is much less important for the control of action than we might think. In this article I push against this trend, developing an understanding of conscious control that is sensitive to our best models of overt (that is, bodily) action control. Further, I assess the cogency of various zombie challenges-challenges that seek to demote the importance of conscious control for human agency. I argue that though nonconscious contributions to action control are evidently robust, these challenges are overblown.

  17. Conscious Control over Action

    PubMed Central

    Shepherd, Joshua

    2015-01-01

    The extensive involvement of nonconscious processes in human behaviour has led some to suggest that consciousness is much less important for the control of action than we might think. In this article I push against this trend, developing an understanding of conscious control that is sensitive to our best models of overt (that is, bodily) action control. Further, I assess the cogency of various zombie challenges—challenges that seek to demote the importance of conscious control for human agency. I argue that though nonconscious contributions to action control are evidently robust, these challenges are overblown. PMID:26113753

  18. Stabilizing bottomless action theories

    NASA Astrophysics Data System (ADS)

    Greensite, J.; Halpern, M. B.

    1984-08-01

    We show how to construct the euclidean quantum theory corresponding to classical actions which are unbounded from below. Our method preserves the classical limit, the large- N limit, and the perturbative expansion of the unstabilized theories.

  19. Benzidine Dyes Action Plan

    EPA Pesticide Factsheets

    This Action Plan addresses the use of benzidine-based dyes and benzidine congener-based dyes, both metalized and non-metalized, in products that would result in consumer exposure, such as for use to color textiles.

  20. Oak Canyon Action Memo

    EPA Pesticide Factsheets

    This memorandum requests approval for a time-critical removal action at the 27 residential properties that compose the Oak Canyon Site located in the Village of Paguate, Pueblo of Laguna, near Cibola County, New Mexico.

  1. [Addictions and action systems].

    PubMed

    Loonis, E; Apter, M J

    2000-01-01

    Generalizing from some previous analyses of addiction, and introducing the concept of an action system which governs all actions which are focussed on what Brown (1988) calls "hedonic management", we argue that addictions of every kind involve an action system that displays high salience, low variety and low vicariance. Addictions also involve what Apter (1982) calls the "paratelic state". A study was carried out comparing 31 drug addicts with 29 control subjects in terms of action system variables. To measure these variables, we constructed a new instrument, the Activity-System Drawing Test, and also used the Telic Dominance Scale to measure frequency of paratelic states. Dysphoria was measured by means of the BATE (anxiety), IDA-13 (depression), SEI (self-esteem), and TAS-20 (alexithymia) instruments. Strongly significant differences were found between groups for both action system variables and dysphoria, and there were also strong correlations between both groups of variables. This supports the idea that addictions emerge from systemic properties of the action system.

  2. Antisymmetric string actions

    NASA Astrophysics Data System (ADS)

    Aragone, C.

    1986-12-01

    An action is presented for the free bosonic string on external flat space in terms of an antisymmetric second-rank string background tensor which is classically equivalent to the Nambu-Goto action. Both action and field equations are entirely described in terms of 2D world-sheet forms, without any reference to a 2D metric tensor background. The analysis of its canonical formulation shows how the quadratic Virasoro constraints are generated in this case and what their connection with the Bianchi identities are. Since in the orthonormal gauge the reduced action coincides with the standard one, it has the same critical dimension D = 26. The existence of an interaction term of a purely geometric structure stemming in the extrinsic curvature is pointed out. Its action and the new string field equations are then derived. This polynomial antisymmetric string action is uniformly generalized in order to describe d < D-dimensional extended objects in D-dimensional flat space. On leave of absence from Departamento de Física, Universidad Simon Bolívar, Apartado 80659, Caracas 1080A, Venezuela.

  3. Practising Virtual Action Learning at University

    ERIC Educational Resources Information Center

    Hauser, Bernhard

    2010-01-01

    The University for Applied Management is a semi-virtual institution widely using blended learning as an integrated approach of face-to-face instruction and e-learning. Virtual action learning is offered in all bachelor and master programmes. The module is transfer orientated and aims at encouraging reflection and supporting students to develop a…

  4. Quality in Action: Closing the Loop

    ERIC Educational Resources Information Center

    Nair, Chenicheri Sid; Pawley, David; Mertova, Patricie

    2010-01-01

    Purpose: This paper aims to report on how an Administrative Division at a research-intensive Australian university utilised feedback data from the Learning and Growth Survey, to initiate changes. Design/methodology/approach: This paper refers to the actions taken by the Administrative Division to the results obtained from the Learning and Growth…

  5. Affirmative Action Training Program for Firemen.

    ERIC Educational Resources Information Center

    MacBain, Z. E.

    This paper summarizes the "Affirmative Action" training of unskilled minorities for jobs as firemen. The various training approaches undertaken are discussed; some were more successful than others. Hopefully, the information provided in this report can be used by other fire departments as a basis for developing their own minority "Affirmative…

  6. Antigravity: Spin-gravity coupling in action

    NASA Astrophysics Data System (ADS)

    Plyatsko, Roman; Fenyk, Mykola

    2016-08-01

    The typical motions of a spinning test particle in Schwarzschild's background which show the strong repulsive action of the highly relativistic spin-gravity coupling are considered using the exact Mathisson-Papapetrou equations. An approximated approach to choice solutions of these equations which describe motions of the particle's proper center of mass is developed.

  7. Due Process in Adverse Personnel Action.

    ERIC Educational Resources Information Center

    Scriven, Michael

    1997-01-01

    A detailed checklist and timeline for ensuring due process are provided for adverse personnel actions, and the need to supplement this with expert, same-jurisdiction legal advice is stressed. This approach emphasizes the importance of treating due process as an ethical as well as a legal requirement. (SLD)

  8. LEAD at Lunch: Inquiry, Learning, and Action

    ERIC Educational Resources Information Center

    Roberts, Cynthia

    2012-01-01

    This account of practice discusses the author's experience in facilitating a small group of managers in health care over lunchtime utilizing an action learning approach. This was part of a larger leadership development initiative which took place in the organization and the intention was to create a more intimate, informal and safe setting whereby…

  9. Plan for early action: Recommendations

    SciTech Connect

    1998-12-31

    This report contains recommendations on the implementation of an action plan to reduce or recapture greenhouse gas (GHG) emissions in British Columbia. The report includes the consensus recommendations of the BC Greenhouse Gas Forum, as well as those items on which Forum participants have agreed to disagree, plus the reasons for those differences. The recommendations include: Umbrella actions which may affect several or all sectors of the economy, or support the success of other actions; actions to reduce vehicle kilometers travelled; actions to increase vehicle efficiency or increase the use of alternative fuels or technologies; actions to decrease GHG emissions from energy production; actions to increase end-use energy efficiency; and actions to reduce non-energy-related emissions. Appendices include work sheets on each action, with a description of the action and information on the action`s rationale, experience elsewhere, related policy initiatives, and key issues regarding feasibility and implementation.

  10. What's an Asthma Action Plan?

    MedlinePlus

    ... to 2-Year-Old What's an Asthma Action Plan? KidsHealth > For Parents > What's an Asthma Action Plan? ... normal everyday activities without having asthma symptoms. Action Plans Are Unique Each person's experience with asthma is ...

  11. Steamlined Approach for Environmental Restoration (SAFER) Plan For Corrective Action Unit 394: Areas 12, 18, and 29, Spill/Release Sites, Nevada Test Site, Nevada (November 2001, Rev. 0)

    SciTech Connect

    U.S. Department of Energy, National Nuclear Security Administration Nevada Operations Office

    2001-09-24

    This plan addresses the actions necessary for the characterization and closure of Corrective Action Unit (CAU) 394: Areas 12, 18, and 29, Spill/Release Sites, identified in the Federal Facility Agreement and Consent Order (FFACO). The CAU, located on the Nevada Test Site, consists of six Corrective Action Sites (CASs): CAS 12-25-04, UST 12-16-2 Waste Oil Release; CAS 18-25-02, Oil Spills; CAS 18-25-02, Oil Spills; CAS 18-25-03, Oil Spill; CAS 18-25-04, Spill (Diesel Fuel); CAS 29-44-01, Fuel Spill (a & b). Process knowledge is the basis for the development of the conceptual site models (CSMs). The CSMs describe the most probable scenario for current conditions at each site, and define the assumptions that are the basis for the SAFER plan. The assumptions are formulated from historical information and process knowledge. Vertical migration of contaminant(s) of potential concern (COPCs) is expected to be predominant over lateral migration in the absence of any barrier (with asphalt /concrete being the exception at least two of the CASs). Soil is the impacted or potentially impacted media at all the sites, with asphalt and/or concrete potentially impacted at two of the CASs. Radionuclides are not expected at any CAS; hydrocarbons are the primary COPC at each CAS, and can be used to guide the investigation; future land-use scenarios limit use to various nonresidential uses; and exposure scenarios are limited by future land-use scenarios to site workers. There is sufficient information and process knowledge from historical documentation regarding the expected nature and extent of potential contaminants to recommend closure of CAU 394 using the SAFER process. On completion of the field activities, a Closure Report will be prepared and submitted to the NDEP for review and approval.

  12. Classifying Facial Actions

    PubMed Central

    Donato, Gianluca; Bartlett, Marian Stewart; Hager, Joseph C.; Ekman, Paul; Sejnowski, Terrence J.

    2010-01-01

    The Facial Action Coding System (FACS) [23] is an objective method for quantifying facial movement in terms of component actions. This system is widely used in behavioral investigations of emotion, cognitive processes, and social interaction. The coding is presently performed by highly trained human experts. This paper explores and compares techniques for automatically recognizing facial actions in sequences of images. These techniques include analysis of facial motion through estimation of optical flow; holistic spatial analysis, such as principal component analysis, independent component analysis, local feature analysis, and linear discriminant analysis; and methods based on the outputs of local filters, such as Gabor wavelet representations and local principal components. Performance of these systems is compared to naive and expert human subjects. Best performances were obtained using the Gabor wavelet representation and the independent component representation, both of which achieved 96 percent accuracy for classifying 12 facial actions of the upper and lower face. The results provide converging evidence for the importance of using local filters, high spatial frequencies, and statistical independence for classifying facial actions. PMID:21188284

  13. ES H action plan

    SciTech Connect

    Not Available

    1991-01-01

    This document contains planned actions to correct the deficiencies identified in the Pre-Tiger Team Self-Assessment (PTTSA), January 1991, of Sandia National Laboratories (SNL -- Albuquerque, New Mexico; Tonopah, Nevada; and Kauai, Hawaii). The Self-Assessment was conducted by a Self-Assessment Working Group consisting of 19 department managers, with support from Environment, Safety, and Health (ES H) professionals, from October through December 1990. Findings from other past audits, dating back to 1985, were reviewed and compared with the PTTSA findings to determine if additional findings, key findings, or root causes were warranted. The resulting ES H Action Plan and individual planned actions were prepared by the ES H Action Plan Project Group with assistance from the Program owners/authors during February and March 1991. The plan was reviewed by SNL Management in April 1991. This document serves as a planning instrument for the Laboratories to aid in the scoping and sizing of activities related to ES H compliance for the coming five years. It will be modified as required to ensure a workload/funding balance and to address the findings resulting from the Tiger Team assessment at SNL, Albuquerque. The process of producing this document has served well to prepare SNL, Albuquerque, for the coming task of producing the required post-Tiger Team action plan document. 8 tabs.

  14. Action languages: Dimensions, effects

    NASA Technical Reports Server (NTRS)

    Hayes, Daniel G.; Streeter, Gordon

    1989-01-01

    Dimensions of action languages are discussed for communication between humans and machines, and the message handling capabilities of object oriented programming systems are examined. Design of action languages is seen to be very contextual. Economical and effective design will depend on features of situations, the tasks intended to be accomplished, and the nature of the devices themselves. Current object oriented systems turn out to have fairly simple and straightforward message handling facilities, which in themselves do little to buffer action or even in some cases to handle competing messages. Even so, it is possible to program a certain amount of discretion about how they react to messages. Such thoughtfulness and perhaps relative autonomy of program modules seems prerequisite to future systems to handle complex interactions in changing situations.

  15. Mitigation Action Plan

    SciTech Connect

    Not Available

    1994-02-01

    This Mitigation Action Plan (MAP) focuses on mitigation commitments stated in the Supplemental Environmental Impact Statement (SEIS) and the Record of Decision (ROD) for the Naval Petroleum Reserve No. 1 (NPR-1). Specific commitments and mitigation implementation actions are listed in Appendix A-Mitigation Actions, and form the central focus of this MAP. They will be updated as needed to allow for organizational, regulatory, or policy changes. It is the intent of DOE to comply with all applicable federal, state, and local environmental, safety, and health laws and regulations. Eighty-six specific commitments were identified in the SEIS and associated ROD which pertain to continued operation of NPR-1 with petroleum production at the Maximum Efficient Rate (MER). The mitigation measures proposed are expected to reduce impacts as much as feasible, however, as experience is gained in actual implementation of these measures, some changes may be warranted.

  16. Characterizations of proper actions

    NASA Astrophysics Data System (ADS)

    Biller, Harald

    2004-03-01

    Three kinds of proper actions of increasing strength are defined. We prove that the three definitions specialize to the definitions by Bourbaki, by Palais and by Baum, Connes and Higson in their respective settings. The third of these, which thus turns out to be the strongest, originally only concerns actions of second countable locally compact groups on metrizable spaces. In this situation, it is shown to coincide with the other two definitions if the total space locally has the Lindelöf property and the orbit space is regular.

  17. Two-Loop Effective Action for Theories with Fermions

    NASA Astrophysics Data System (ADS)

    Faizullaev, B. A.; Musakhanov, M. M.

    1995-08-01

    On the basis of a new approach for the calculation of the effective action developed in our previous works we calculate the effective action (up to two-loop level) for some models containing fermion fields. This method allows us to calculate the fermionic part of the effective action properly. The two-loop contribution to the effective potential for the Nambu-Jona-Lasinio model is calculated and is shown to vanish.

  18. Time will show: real time predictions during interpersonal action perception.

    PubMed

    Manera, Valeria; Schouten, Ben; Verfaillie, Karl; Becchio, Cristina

    2013-01-01

    Predictive processes are crucial not only for interpreting the actions of individual agents, but also to predict how, in the context of a social interaction between two agents, the actions of one agent relate to the actions of a second agent. In the present study we investigated whether, in the context of a communicative interaction between two agents, observers can use the actions of one agent to predict when the action of a second agent will take place. Participants observed point-light displays of two agents (A and B) performing separate actions. In the communicative condition, the action performed by agent B responded to a communicative gesture performed by agent A. In the individual condition, agent A's communicative action was substituted with a non-communicative action. For each condition, we manipulated the temporal coupling of the actions of the two agents, by varying the onset of agent A's action. Using a simultaneous masking detection task, we demonstrated that the timing manipulation had a critical effect on the communicative condition, with the visual discrimination of agent B increasing linearly while approaching the original interaction timing. No effect of the timing manipulation was found for the individual condition. Our finding complements and extends previous evidence for interpersonal predictive coding, suggesting that the communicative gestures of one agent can serve not only to predict what the second agent will do, but also when his/her action will take place.

  19. Bayesian Clinical Trials in Action

    PubMed Central

    Lee, J. Jack; Chu, Caleb T.

    2012-01-01

    Although the frequentist paradigm has been the predominant approach to clinical trial design since the 1940s, it has several notable limitations. The alternative Bayesian paradigm has been greatly enhanced by advancements in computational algorithms and computer hardware. Compared to its frequentist counterpart, the Bayesian framework has several unique advantages, and its incorporation into clinical trial design is occurring more frequently. Using an extensive literature review to assess how Bayesian methods are used in clinical trials, we find them most commonly used for dose finding, efficacy monitoring, toxicity monitoring, diagnosis/decision making, and for studying pharmacokinetics/pharmacodynamics. The additional infrastructure required for implementing Bayesian methods in clinical trials may include specialized software programs to run the study design, simulation, and analysis, and Web-based applications, which are particularly useful for timely data entry and analysis. Trial success requires not only the development of proper tools but also timely and accurate execution of data entry, quality control, adaptive randomization, and Bayesian computation. The relative merit of the Bayesian and frequentist approaches continues to be the subject of debate in statistics. However, more evidence can be found showing the convergence of the two camps, at least at the practical level. Ultimately, better clinical trial methods lead to more efficient designs, lower sample sizes, more accurate conclusions, and better outcomes for patients enrolled in the trials. Bayesian methods offer attractive alternatives for better trials. More such trials should be designed and conducted to refine the approach and demonstrate its real benefit in action. PMID:22711340

  20. Bayesian clinical trials in action.

    PubMed

    Lee, J Jack; Chu, Caleb T

    2012-11-10

    Although the frequentist paradigm has been the predominant approach to clinical trial design since the 1940s, it has several notable limitations. Advancements in computational algorithms and computer hardware have greatly enhanced the alternative Bayesian paradigm. Compared with its frequentist counterpart, the Bayesian framework has several unique advantages, and its incorporation into clinical trial design is occurring more frequently. Using an extensive literature review to assess how Bayesian methods are used in clinical trials, we find them most commonly used for dose finding, efficacy monitoring, toxicity monitoring, diagnosis/decision making, and studying pharmacokinetics/pharmacodynamics. The additional infrastructure required for implementing Bayesian methods in clinical trials may include specialized software programs to run the study design, simulation and analysis, and web-based applications, all of which are particularly useful for timely data entry and analysis. Trial success requires not only the development of proper tools but also timely and accurate execution of data entry, quality control, adaptive randomization, and Bayesian computation. The relative merit of the Bayesian and frequentist approaches continues to be the subject of debate in statistics. However, more evidence can be found showing the convergence of the two camps, at least at the practical level. Ultimately, better clinical trial methods lead to more efficient designs, lower sample sizes, more accurate conclusions, and better outcomes for patients enrolled in the trials. Bayesian methods offer attractive alternatives for better trials. More Bayesian trials should be designed and conducted to refine the approach and demonstrate their real benefit in action.

  1. Fractional Action Cosmology with Variable Order Parameter

    NASA Astrophysics Data System (ADS)

    El-Nabulsi, Rami Ahmad

    2017-01-01

    Fractional action cosmology with variable order parameter was constructed in this paper. Starting from a fractional weighted action which generalizes the fractional actionlike variational approach, a large number of cosmological dynamical equations are obtained depending on the mathematical type of the fractional order parameter. Through this paper, we selected two independent types which result on a number of cosmological scenarios and we discussed their dynamical consequences. It was observed that the present fractional cosmological formalism holds a large family of solutions and offers new features not found in the standard formalism and in many fundamental research papers.

  2. Fractional Action Cosmology with Variable Order Parameter

    NASA Astrophysics Data System (ADS)

    El-Nabulsi, Rami Ahmad

    2017-04-01

    Fractional action cosmology with variable order parameter was constructed in this paper. Starting from a fractional weighted action which generalizes the fractional actionlike variational approach, a large number of cosmological dynamical equations are obtained depending on the mathematical type of the fractional order parameter. Through this paper, we selected two independent types which result on a number of cosmological scenarios and we discussed their dynamical consequences. It was observed that the present fractional cosmological formalism holds a large family of solutions and offers new features not found in the standard formalism and in many fundamental research papers.

  3. Angels in Action

    ERIC Educational Resources Information Center

    Stylianou, Xanthippi Cynthia

    2009-01-01

    In this article, the author discusses the importance of the placement of action lines to show the direction of movement. The author shows some visuals of angels and discusses in details the texture of the wings, the hair and the clothing.

  4. Executive Mind, Timely Action.

    ERIC Educational Resources Information Center

    Torbert, William R.

    1983-01-01

    The idea of "Executive Mind" carries with it the notion of purposeful and effective action. Part I of this paper characterizes three complements to "Executive Mind"--"Observing Mind,""Theorizing Mind," and "Passionate Mind"--and offers historical figures exemplifying all four types. The concluding…

  5. College Comedy and Action

    ERIC Educational Resources Information Center

    Moore, Rosanna

    1977-01-01

    A few materials such as yarn and scraps of paper and cloth can provide the media for recording limitless ideas from the imaginations of students. With a little encouragement and a few suggestions of actions, emotions, exaggerations and activities students will produce a vast array of amusing characters. (Author)

  6. Affirmative Action Plan.

    ERIC Educational Resources Information Center

    Triton Coll., River Grove, IL.

    In order to develop an affirmative action plan at Triton College, the college President appointed a committee made up of nine representatives from the various college constituencies, the majority of which were women and minorities, to determine the objectives to be achieved and how to implement them, and to establish appropriate review procedures.…

  7. Youth Engaged for Action

    ERIC Educational Resources Information Center

    Post, Margaret; Little, Priscilla

    2005-01-01

    This article examines how out-of-school time programs can promote youth involvement in civic action by focusing on four interrelated programmatic strategies: establishing organizational readiness that fosters engagement; promoting youth-adult partnerships; engaging youth as leaders and decision makers; and involving youth in research and…

  8. Expert Teacher Action Program.

    ERIC Educational Resources Information Center

    Washington, Eva

    The expert teacher action program is to improve classroom teaching performance. The program has been tested in workshop sessions involving more than 1,200 educators representing 50 school districts. A set of standards, consisting of 25 variables, lead to the definition of expert teaching. Each variable deals with a major aspect of the duties of…

  9. Court Action for Migrants.

    ERIC Educational Resources Information Center

    Ewald, Thomas R.

    Aiding attorneys who represent migrant farmworkers and their families when affirmative civil action is required, this book helps to raise the level of migrants' legal protection to a minimum standard of adequacy. The text is based on the Federal Rules of Civil Procedure, a national set of rules. The book is divided into 3 sections: the…

  10. Action for Children's Television.

    ERIC Educational Resources Information Center

    Ranly, Donald P.

    The origins, development, and effectiveness of Action for Children's Television (ACT) are examined in this pamphlet. The strategies used by ACT to obtain change at the congressional level and within television stations and networks include the following: a "tuneout" day when people are urged to turn off their television sets, a boycott…

  11. School Reform in Action.

    ERIC Educational Resources Information Center

    Miller, A. Christine

    This study describes and analyzes the impact on student learning and the learning environment of 55 schools in Broward, Palm Beach, and Miami-Dade school districts as they implemented the schoolwide action-research framework for school improvement. Interviews, observations, document review during site visits, school framework reports, surveys,…

  12. Cognitive framing in action.

    PubMed

    Huhn, John M; Potts, Cory Adam; Rosenbaum, David A

    2016-06-01

    Cognitive framing effects have been widely reported in higher-level decision-making and have been ascribed to rules of thumb for quick thinking. No such demonstrations have been reported for physical action, as far as we know, but they would be expected if cognition for physical action is fundamentally similar to cognition for higher-level decision-making. To test for such effects, we asked participants to reach for a horizontally-oriented pipe to move it from one height to another while turning the pipe 180° to bring one end (the "business end") to a target on the left or right. From a physical perspective, participants could have always rotated the pipe in the same angular direction no matter which end was the business end; a given participant could have always turned the pipe clockwise or counter-clockwise. Instead, our participants turned the business end counter-clockwise for left targets and clockwise for right targets. Thus, the way the identical physical task was framed altered the way it was performed. This finding is consistent with the hypothesis that cognition for physical action is fundamentally similar to cognition for higher-level decision-making. A tantalizing possibility is that higher-level decision heuristics have roots in the control of physical action, a hypothesis that accords with embodied views of cognition.

  13. Nutrition Action Pack.

    ERIC Educational Resources Information Center

    Sockut, Joanne; Stumpe, Stephanie

    One of five McDonald's Action Packs, these instructional materials integrate elementary school-level nutrition education into other disciplines--biology, sociology, physiology, mathematics, and art. Contents include four units consisting of twelve activities. Unit 1, Why You Need Food, is a self-examination of what is needed for growth, health,…

  14. Sustainability as Moral Action

    ERIC Educational Resources Information Center

    Dunn, Merrily S.; Hart-Steffes, Jeanne S.

    2012-01-01

    When one considers sustainability as a moral action, there are equally complex realities at hand--climate change, resource depletion, water and land rights. One author describes this broad sense of sustainability as "the connection of specific social and environmental problems to the functioning of human and ecological systems" (Jenkins, 2011).…

  15. Conjugate flow action functionals

    NASA Astrophysics Data System (ADS)

    Venturi, Daniele

    2013-11-01

    We present a new general framework to construct an action functional for a non-potential field theory. The key idea relies on representing the governing equations relative to a diffeomorphic flow of curvilinear coordinates which is assumed to be functionally dependent on the solution field. Such flow, which will be called the conjugate flow, evolves in space and time similarly to a physical fluid flow of classical mechanics and it can be selected in order to symmetrize the Gâteaux derivative of the field equations with respect to suitable local bilinear forms. This is equivalent to requiring that the governing equations of the field theory can be derived from a principle of stationary action on a Lie group manifold. By using a general operator framework, we obtain the determining equations of such manifold and the corresponding conjugate flow action functional. In particular, we study scalar and vector field theories governed by second-order nonlinear partial differential equations. The identification of transformation groups leaving the conjugate flow action functional invariant could lead to the discovery of new conservation laws in fluid dynamics and other disciplines.

  16. Economics Action Pack.

    ERIC Educational Resources Information Center

    McDonald's Corp., Oak Brook, IL.

    One of five McDonald's Action Packs, this learning package introduces intermediate grade students to basic economic concepts. The fourteen activities include the topics of consumption (4 activities), production (5), the market system (3), a pretest, and a posttest. Specific titles under consumption include The Wonderful Treasure Tree (introduction…

  17. From Awareness to Action

    ERIC Educational Resources Information Center

    Micklos, John, Jr.

    2012-01-01

    What inspires young people to become activists? Events such as wars or regime changes obviously raise high emotions. But some choose to get involved because they saw a need and felt compelled to take action. Young Americans have a long track record as activists. Among other things, they played a key role in the civil rights movement of the 1950s…

  18. Affirmative Action Fallout

    ERIC Educational Resources Information Center

    Roach, Ronald

    2005-01-01

    Race-conscious affirmative action in higher education survived a close challenge in 2003 when the U.S. Supreme Court ruled that race was a valid academic admission criteria in the "Grutter v. Bollinger" case. Two years later, a number of "pipeline" programs to help under-represented minorities gain admission to and complete graduate school have…

  19. Conjugate flow action functionals

    SciTech Connect

    Venturi, Daniele

    2013-11-15

    We present a new general framework to construct an action functional for a non-potential field theory. The key idea relies on representing the governing equations relative to a diffeomorphic flow of curvilinear coordinates which is assumed to be functionally dependent on the solution field. Such flow, which will be called the conjugate flow, evolves in space and time similarly to a physical fluid flow of classical mechanics and it can be selected in order to symmetrize the Gâteaux derivative of the field equations with respect to suitable local bilinear forms. This is equivalent to requiring that the governing equations of the field theory can be derived from a principle of stationary action on a Lie group manifold. By using a general operator framework, we obtain the determining equations of such manifold and the corresponding conjugate flow action functional. In particular, we study scalar and vector field theories governed by second-order nonlinear partial differential equations. The identification of transformation groups leaving the conjugate flow action functional invariant could lead to the discovery of new conservation laws in fluid dynamics and other disciplines.

  20. The Constitution in Action

    ERIC Educational Resources Information Center

    Potter, Lee Ann

    2007-01-01

    In this article, the author describes the experiences middle school students on a field trip to the new Constitution in Action Learning Lab in the Boeing Learning Center at the National Archives can expect. There, middle school students take on the roles of archivists and researchers collecting and analyzing primary sources from the holdings of…

  1. Jump into Action

    ERIC Educational Resources Information Center

    Ball, Stephen; Cohen, Ann; Meyer, Margaret

    2012-01-01

    Jump Into Action (JIA) is a school-based team-taught program to help fifth-grade students make healthy food choices and be more active. The JIA team (physical education teacher, classroom teacher, school nurse, and parent) work together to provide a supportive environment as students set goals to improve food choices and increase activity.…

  2. Hope for Environmental Action

    ERIC Educational Resources Information Center

    Fleischer, Barbara J.; DeMoor, Emily

    2015-01-01

    Environmental consciousness-raising programs tend to emphasize the magnitude of imminent ecological disasters, if humans continue on their current trajectory. While these environmental literacy programs also call for action to avoid cataclysmic ecological changes, psychological research on "learned helplessness" suggests that information…

  3. Action Learning Issues.

    ERIC Educational Resources Information Center

    1998

    This document contains four papers from a symposium on adult learning issues and human resource development (HRD). "Creating a Systemic Framework for the Transfer of Learning from an Action Learning Experience" (Suzanne D. Butterfield, Kitty Gold, Verna J. Willis) discusses a study of the organizational elements that affect learning and…

  4. Target: Development Action.

    ERIC Educational Resources Information Center

    American Freedom from Hunger Foundation, Washington, DC. Young World Development.

    This handbook, suggestive rather than prescriptive, is written for Young World Development and/or similar groups committed to active involvement in community, national, and world improvement. Emphasis is upon organizing high school, college, and adult courses and action programs in the community which will help sensitize participants and make them…

  5. Justifying Action Research

    ERIC Educational Resources Information Center

    Helskog, Guro Hansen

    2014-01-01

    In this paper I use a general philosophy of science perspective in looking at the problem of justifying action research. First I try to clarify the concept of justification, by contrasting it with the concept of validity, which seems to be used almost as a synonym in some parts of the literature. I discuss the need for taking a stand in relation…

  6. Classroom Assessment in Action

    ERIC Educational Resources Information Center

    Shermis, Mark D.; DiVesta, Francis J.

    2011-01-01

    "Classroom Assessment in Action" clarifies the multi-faceted roles of measurement and assessment and their applications in a classroom setting. Comprehensive in scope, Shermis and Di Vesta explain basic measurement concepts and show students how to interpret the results of standardized tests. From these basic concepts, the authors then…

  7. Quick action clamp

    NASA Technical Reports Server (NTRS)

    Calco, Frank S. (Inventor)

    1991-01-01

    A quick release toggle clamp that utilizes a spring that requires a deliberate positive action for disengagement is presented. The clamp has a sliding bolt that provides a latching mechanism. The bolt is moved by a handle that tends to remain in an engaged position while under tension.

  8. SYRACUSE ACTION FOR YOUTH.

    ERIC Educational Resources Information Center

    ADDINGTON, HAROLD E.; AND OTHERS

    A PROPOSAL WAS MADE TO PREVENT AND CONTROL JUVENILE DELINQUENCY BY OPENING OPPORTUNITIES AND DEVELOPING COMPETENCE AMONG DISADVANTAGED YOUTH. THE TOTAL COMMUNITY WAS MOBILIZED TO DEVELOP A PROGRAM TO ATTACK THE PROBLEM AT ALL LEVELS THEY WORKED FOR 18 MONTHS TO PLAN A SERIES OF CREATIVE ACTION PROGRAMS IN EDUCATION, EMPLOYMENT, AND COMMUNITY…

  9. Affirmative Action Plan.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh.

    This affirmative action (AA) guide is intended to identify and remove discriminatory employment practices that may still exist in the North Carolina State Department of Public Instruction (DPI). DPI extends equal employment opportunity (EEO) to all applicants and employees without regard to race, color, religion, sex, age, handicap, political…

  10. The Shape of Action

    ERIC Educational Resources Information Center

    Hard, Bridgette Martin; Recchia, Gabriel; Tversky, Barbara

    2011-01-01

    How do people understand the everyday, yet intricate, behaviors that unfold around them? In the present research, we explored this by presenting viewers with self-paced slideshows of everyday activities and recording looking times, subjective segmentation (breakpoints) into action units, and slide-to-slide physical change. A detailed comparison of…

  11. The Construction of Career through Goal-Directed Action

    ERIC Educational Resources Information Center

    Young, Richard A.; Valach, Ladislav

    2004-01-01

    The thesis of this article is that occupational career is constructed through a system of intentional, goal-directed processes in the form of actions and projects as well as other careers, such as the family career and relationship careers. A contextual action theory of career is proposed as an approach that reflects a constructionist stance and…

  12. Improving Educational Aspirations and Outcomes through Community Action Research

    ERIC Educational Resources Information Center

    Bleach, Josephine

    2013-01-01

    This paper examines how a community action research approach supported the implementation of an educational support programme for children, parents and local educators. The aim was the creation of a learning community that acknowledged, valued and used the expertise and experience of all involved. The action reflection cycle informed the…

  13. Motivated Action Theory: A Formal Theory of Causal Reasoning.

    DTIC Science & Technology

    1991-12-01

    approaches to temporal reasoning, and their shortcomings, in light of this analysis. We propose a new system for causal reasoning, motivated action theory , which...builds upon causation as a crucial preference criterion. Motivated action theory solves the traditional problems of both forward and backward

  14. Collective Action Competence: An Asset to Campus Sustainability

    ERIC Educational Resources Information Center

    Clark, Charlotte R.

    2016-01-01

    Purpose: The purpose of this paper is to operationalize theories of social learning and collective action for campus sustainability practitioners at higher education institutions (IHEs) to enhance their work, and to introduce the concept of collective action competence as a practical tool. Design/methodology/approach: This paper presents a…

  15. An Action-Research Project: Community Lead Poisoning Prevention

    ERIC Educational Resources Information Center

    Rajaram, Shireen S.

    2007-01-01

    This action-research project focused on gathering data on awareness of lead poisoning, as well as disseminating information on lead poisoning prevention in a metropolitan midwestern city. This project reflects an action-research approach to service learning and was in collaboration with a grass-roots organization. This paper outlines the daunting…

  16. Agroecology Education: Action-Oriented Learning and Research

    ERIC Educational Resources Information Center

    Lieblein, Geir; Breland, Tor Arvid; Francis, Charles; Ostergaard, Edvin

    2012-01-01

    Purpose: This article examines and evaluates the potential contributions from action learning and action research with stakeholders to higher education in agriculture and food systems. Design/Methodology/Approach: The research is based on our experiences over the past two decades of running PhD courses and an MSc degree programme in Agroecology in…

  17. Action and Organizational Learning in an Elevator Company

    ERIC Educational Resources Information Center

    De Loo, Ivo

    2006-01-01

    Purpose: To highlight the relevance of management control in action learning programs that aim to foster organizational learning. Design/methodology/approach: Literature review plus case study. The latter consists of archival analysis and multiple interviews. Findings: When action learning programs are built around singular learning experiences,…

  18. Action Learning: Nothing So Practical as a Good Theory

    ERIC Educational Resources Information Center

    Mumford, Alan

    2006-01-01

    Kurt Lewin's epigrammatic paradox is particularly true for action learning. Marquardt and Waddill (2004), and previously Yorks O'Neil and Marsick (1999) have approached the issue of the relationship between theory and action learning by looking at a variety of theories which they have placed in "schools". This provides an interesting analysis, but…

  19. For the Record: It's Time to Spring into Action Research!

    ERIC Educational Resources Information Center

    Garrett, Joyce Lynn

    2006-01-01

    Action research is a systematic approach used by practitioners to conceive questions and control methodologies, and to explore classroom or school-based problems. Action research is the perfect marriage of theory and practice. Recent trends in education, such as professional development schools, data-driven decision making, and undergraduate…

  20. Hierarchical human action recognition around sleeping using obscured posture information

    NASA Astrophysics Data System (ADS)

    Kudo, Yuta; Sashida, Takehiko; Aoki, Yoshimitsu

    2015-04-01

    This paper presents a new approach for human action recognition around sleeping with the human body parts locations and the positional relationship between human and sleeping environment. Body parts are estimated from the depth image obtained by a time-of-flight (TOF) sensor using oriented 3D normal vector. Issues in action recognition of sleeping situation are the demand of availability in darkness, and hiding of the human body by duvets. Therefore, the extraction of image features is difficult since color and edge features are obscured by covers. Thus, first in our method, positions of four parts of the body (head, torso, thigh, and lower leg) are estimated by using the shape model of bodily surface constructed by oriented 3D normal vector. This shape model can represent the surface shape of rough body, and is effective in robust posture estimation of the body hidden with duvets. Then, action descriptor is extracted from the position of each body part. The descriptor includes temporal variation of each part of the body and spatial vector of position of the parts and the bed. Furthermore, this paper proposes hierarchical action classes and classifiers to improve the indistinct action classification. Classifiers are composed of two layers, and recognize human action by using the action descriptor. First layer focuses on spatial descriptor and classifies action roughly. Second layer focuses on temporal descriptor and classifies action finely. This approach achieves a robust recognition of obscured human by using the posture information and the hierarchical action recognition.

  1. WIPP Facility Work Plan for Solid Waste Management Units

    SciTech Connect

    Washington TRU Solutions LLC

    2000-02-25

    This Facility Work Plan (FWP) has been prepared as required by Module VII,Section VII.M.1 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Permit, NM4890139088-TSDF (the Permit); (NMED, 1999a). This work plan describes the programmatic facility-wide approach to future investigations at Solid Waste Management Units (SWMUs) and Areas of Concern (AOCs) specified in the Permit. This FWP addresses the current Permit requirements. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) specified in Module VII of the Permit, current New Mexico Environment Department (NMED) guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI Work Plan and Report sequence with a more flexible decision-making approach. The ACAA process allows a Facility to exit the schedule of compliance contained in the Facility’s Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA process can be entered either before or after an RFI Work Plan. According to NMED’s guidance, a facility can prepare an RFI Work Plan or Sampling and Analysis Plan (SAP) for any SWMU or AOC (NMED, 1998). Based on this guidance, a SAP constitutes an acceptable alternative to the RFI Work Plan specified in the Permit. The scope of work for the RFI Work Plan or SAP is being developed by the Permittees. The final content of the RFI Work Plan or SAP will be coordinated with the NMED for submittal on May 24, 2000. Specific project-related planning information will be included in the RFI Work Plan or SAP. The SWMU program at WIPP began in 1994 under U.S. Environmental Protection Agency (EPA) regulatory authority. NMED subsequently received regulatory authority from EPA

  2. Measurement Models for Reasoned Action Theory.

    PubMed

    Hennessy, Michael; Bleakley, Amy; Fishbein, Martin

    2012-03-01

    Quantitative researchers distinguish between causal and effect indicators. What are the analytic problems when both types of measures are present in a quantitative reasoned action analysis? To answer this question, we use data from a longitudinal study to estimate the association between two constructs central to reasoned action theory: behavioral beliefs and attitudes toward the behavior. The belief items are causal indicators that define a latent variable index while the attitude items are effect indicators that reflect the operation of a latent variable scale. We identify the issues when effect and causal indicators are present in a single analysis and conclude that both types of indicators can be incorporated in the analysis of data based on the reasoned action approach.

  3. RCRA corrective action -- A practical guide

    SciTech Connect

    Abbasi, R.A.

    1995-10-01

    Under the 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act, the Environmental Protection Agency requires treatment, storage and disposal facilities to investigate and remediate sites on which a release from solid waste management units has occurred. SWMUs include landfills, surface impoundments, waste piles, land treatment facilities, injection wells and container storage areas. HSWA requires corrective action for RCRA-permitted facilities and those with an interim status designation. Corrective actions can be implemented with relative ease at smaller facilities with a few SWMUs. However, larger facilities can be a regulatory nightmare, requiring a more comprehensive approach to corrective action. In such cases, facility managers must be more creative in analyzing the implementation process and ensuring that consistency among SWMUs is not jeopardized.

  4. Measurement Models for Reasoned Action Theory

    PubMed Central

    Hennessy, Michael; Bleakley, Amy; Fishbein, Martin

    2012-01-01

    Quantitative researchers distinguish between causal and effect indicators. What are the analytic problems when both types of measures are present in a quantitative reasoned action analysis? To answer this question, we use data from a longitudinal study to estimate the association between two constructs central to reasoned action theory: behavioral beliefs and attitudes toward the behavior. The belief items are causal indicators that define a latent variable index while the attitude items are effect indicators that reflect the operation of a latent variable scale. We identify the issues when effect and causal indicators are present in a single analysis and conclude that both types of indicators can be incorporated in the analysis of data based on the reasoned action approach. PMID:23243315

  5. A Metadata Action Language

    NASA Technical Reports Server (NTRS)

    Golden, Keith; Clancy, Dan (Technical Monitor)

    2001-01-01

    The data management problem comprises data processing and data tracking. Data processing is the creation of new data based on existing data sources. Data tracking consists of storing metadata descriptions of available data. This paper addresses the data management problem by casting it as an AI planning problem. Actions are data-processing commands, plans are dataflow programs and goals are metadata descriptions of desired data products. Data manipulation is simply plan generation and execution, and a key component of data tracking is inferring the effects of an observed plan. We introduce a new action language for data management domains, called ADILM. We discuss the connection between data processing and information integration and show how a language for the latter must be modified to support the former. The paper also discusses information gathering within a data-processing framework, and show how ADILM metadata expressions are a generalization of Local Completeness.

  6. Adipokines and insulin action

    PubMed Central

    Knights, Alexander J; Funnell, Alister PW; Pearson, Richard CM; Crossley, Merlin; Bell-Anderson, Kim S

    2014-01-01

    Obesity is a major public health concern and a strong risk factor for insulin resistance, type 2 diabetes mellitus (T2DM), and cardiovascular disease. The last two decades have seen a reconsideration of the role of white adipose tissue (WAT) in whole body metabolism and insulin action. Adipose tissue-derived cytokines and hormones, or adipokines, are likely mediators of metabolic function and dysfunction. While several adipokines have been associated with obese and insulin-resistant phenotypes, a select group has been linked with insulin sensitivity, namely leptin, adiponectin, and more recently, adipolin. What is known about these insulin-sensitizing molecules and their effects in healthy and insulin resistant states is the subject of this review. There remains a significant amount of research to do to fully elucidate the mechanisms of action of these adipokines for development of therapeutics in metabolic disease. PMID:24719781

  7. Atoms in Action

    SciTech Connect

    2009-01-01

    This movie produced with Berkeley Lab's TEAM 0.5 microscope shows the growth of a hole and the atomic edge reconstruction in a graphene sheet. An electron beam focused to a spot on the sheet blows out the exposed carbon atoms to make the hole. The carbon atoms then reposition themselves to find a stable configuration. http://newscenter.lbl.gov/press-releases/2009/03/26/atoms-in-action/

  8. Battle Space Action Centers

    DTIC Science & Technology

    2011-05-14

    VREEDE, G. J. D., & KOLFSCHOTEN, G. L . (2008). Extending the contextual and organizational elements of adaptive structurization theory in GSS...Reiter-Palmon, R., & Harland, L . (2009). Computer Assisted Collaboration Engineering and Process Support Systems: The BattleSpace ActionCenters...Collaboration Science, 27 February, University of Nebraska at Omaha, Omaha, NE. 18. BRIGGS, R.O., VREEDE, G.J. DE, REITER-PALMON, R., HARLAND, L

  9. Finding minimal action sequences with a simple evaluation of actions

    PubMed Central

    Shah, Ashvin; Gurney, Kevin N.

    2014-01-01

    Animals are able to discover the minimal number of actions that achieves an outcome (the minimal action sequence). In most accounts of this, actions are associated with a measure of behavior that is higher for actions that lead to the outcome with a shorter action sequence, and learning mechanisms find the actions associated with the highest measure. In this sense, previous accounts focus on more than the simple binary signal of “was the outcome achieved?”; they focus on “how well was the outcome achieved?” However, such mechanisms may not govern all types of behavioral development. In particular, in the process of action discovery (Redgrave and Gurney, 2006), actions are reinforced if they simply lead to a salient outcome because biological reinforcement signals occur too quickly to evaluate the consequences of an action beyond an indication of the outcome's occurrence. Thus, action discovery mechanisms focus on the simple evaluation of “was the outcome achieved?” and not “how well was the outcome achieved?” Notwithstanding this impoverishment of information, can the process of action discovery find the minimal action sequence? We address this question by implementing computational mechanisms, referred to in this paper as no-cost learning rules, in which each action that leads to the outcome is associated with the same measure of behavior. No-cost rules focus on “was the outcome achieved?” and are consistent with action discovery. No-cost rules discover the minimal action sequence in simulated tasks and execute it for a substantial amount of time. Extensive training, however, results in extraneous actions, suggesting that a separate process (which has been proposed in action discovery) must attenuate learning if no-cost rules participate in behavioral development. We describe how no-cost rules develop behavior, what happens when attenuation is disrupted, and relate the new mechanisms to wider computational and biological context. PMID:25506326

  10. Platform for Action: update.

    PubMed

    1995-01-01

    The Center for Women's Global Leadership (CWGL) has collaborated in the preparation of amendments and strategies designed to withstand the challenges being posed to the Platform for Action of the Fourth World Conference on Women. Specific challenges include the inappropriate use of the word "universal" to modify "human rights." This implies that some human rights are less than universal. The strategy proposed is to accept the use of the word "universal" in this context only when it affirms principles of universality contained in the Vienna Programme of Action and not where its use would restrict the rights to which women are entitled. A second concern is over the use of the word "equity" rather than "equality" when referring to gender relations. The use of these terms will be carefully monitored to insure that "equity" not be used to undermine the principle of gender equality. The third concern is the efforts of some governments to hinder the integration of women's human rights throughout the UN system. Such efforts will be opposed. Fourth, the CWGL will seek the inclusion of language which recognizes the barriers that different groups of women face when trying to secure their rights. Finally, the CWGL will propose inclusion of language recognizing and protecting sexual orientation rights. The CWGL is also going to work to translate the abstract language of the Platform for Action into political organizing potential to insure that governments will follow through on their agreements.

  11. Empirical microeconomics action functionals

    NASA Astrophysics Data System (ADS)

    Baaquie, Belal E.; Du, Xin; Tanputraman, Winson

    2015-06-01

    A statistical generalization of microeconomics has been made in Baaquie (2013), where the market price of every traded commodity, at each instant of time, is considered to be an independent random variable. The dynamics of commodity market prices is modeled by an action functional-and the focus of this paper is to empirically determine the action functionals for different commodities. The correlation functions of the model are defined using a Feynman path integral. The model is calibrated using the unequal time correlation of the market commodity prices as well as their cubic and quartic moments using a perturbation expansion. The consistency of the perturbation expansion is verified by a numerical evaluation of the path integral. Nine commodities drawn from the energy, metal and grain sectors are studied and their market behavior is described by the model to an accuracy of over 90% using only six parameters. The paper empirically establishes the existence of the action functional for commodity prices that was postulated to exist in Baaquie (2013).

  12. Archetypes as action patterns.

    PubMed

    Hogenson, George B

    2009-06-01

    The discovery of mirror neurons by researchers at the University of Parma promises to radically alter our understanding of fundamental cognitive and affective states. This paper explores the relationship of mirror neurons to Jung's theory of archetypes and proposes that archetypes may be viewed as elementary action patterns. The paper begins with a review of a proposed interpretation of the fainting spells of S. Freud in his relationship with Jung as an example of an action pattern that also defines an archetypal image. The challenge that mirror neurons present to traditional views in analytical psychology and psychoanalysis, however, is that they operate without recourse to a cognitive processing element. This is a position that is gaining increasing acceptance in other fields as well. The paper therefore reviews the most recent claims made by the Boston Process of Change Study Group as well as conclusions drawn from dynamic systems views of development and theoretical robotics to underline the conclusion that unconscious agency is not a requirement for coherent action. It concludes with the suggestion that this entire body of research may lead to the conclusion that the dynamic unconscious is an unnecessary hypothesis in psychoanalysis and analytical psychology.

  13. Discourse, action, rhetoric: from a perception to an action paradigm in social psychology.

    PubMed

    Durrheim, Kevin

    2012-09-01

    This article provides a personal account of how discursive social psychology has been used to understand social and political change in South Africa and to reflect on the strengths and limitations of the approach. While celebrating the shift from the perception paradigm to the genuinely social constructionist focus on discursive interaction, the article also argues for an expanded focus on embodied action.

  14. Action spectra for photosynthetic inhibition

    NASA Technical Reports Server (NTRS)

    Caldwell, M. M.; Flint, S.; Camp, L. B.

    1981-01-01

    The ultraviolet action spectrum for photosynthesis inhibition was determined to fall between that of the general DNA action spectrum and the generalized plant action spectrum. The characteristics of this action spectrum suggest that a combination of pronounced increase in effectiveness with decreasing wavelength, substantial specificity for the UV-B waveband, and very diminished response in the UV-A waveband result in large radiation amplification factors when the action spectra are used as weighting functions. Attempted determination of dose/response relationships for leaf disc inhibition provided inconclusive data from which to deconvolute an action spectrum.

  15. Modelling the control of interceptive actions.

    PubMed Central

    Beek, P J; Dessing, J C; Peper, C E; Bullock, D

    2003-01-01

    In recent years, several phenomenological dynamical models have been formulated that describe how perceptual variables are incorporated in the control of motor variables. We call these short-route models as they do not address how perception-action patterns might be constrained by the dynamical properties of the sensory, neural and musculoskeletal subsystems of the human action system. As an alternative, we advocate a long-route modelling approach in which the dynamics of these subsystems are explicitly addressed and integrated to reproduce interceptive actions. The approach is exemplified through a discussion of a recently developed model for interceptive actions consisting of a neural network architecture for the online generation of motor outflow commands, based on time-to-contact information and information about the relative positions and velocities of hand and ball. This network is shown to be consistent with both behavioural and neurophysiological data. Finally, some problems are discussed with regard to the question of how the motor outflow commands (i.e. the intended movement) might be modulated in view of the musculoskeletal dynamics. PMID:14561342

  16. ICDF Complex Remedial Action Work Plan

    SciTech Connect

    W. M. Heileson

    2006-12-01

    This Remedial Action Work Plan provides the framework for operation of the Idaho Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Disposal Facility Complex (ICDF). This facility includes (a) an engineered landfill that meets the substantial requirements of DOE Order 435.1, Resource Conservation and Recovery Act Subtitle C, Idaho Hazardous Waste Management Act, and Toxic Substances Control Act polychlorinated biphenyl landfill requirements; (b) centralized receiving, inspections, administration, storage/staging, and treatment facilities necessary for CERCLA investigation-derived, remedial, and removal waste at the Idaho National Laboratory (INL) prior to final disposition in the disposal facility or shipment off-Site; and (c) an evaporation pond that has been designated as a corrective action management unit. The ICDF Complex, including a buffer zone, will cover approximately 40 acres, with a landfill disposal capacity of approximately 510,000 yd3. The ICDF Complex is designed and authorized to accept INL CERCLA-generated wastes, and includes the necessary subsystems and support facilities to provide a complete waste management system. This Remedial Action Work Plan presents the operational approach and requirements for the various components that are part of the ICDF Complex. Summaries of the remedial action work elements are presented herein, with supporting information and documents provided as appendixes to this work plan that contain specific detail about the operation of the ICDF Complex. This document presents the planned operational process based upon an evaluation of the remedial action requirements set forth in the Operable Unit 3-13 Final Record of Decision.

  17. Inferring learners' knowledge from their actions.

    PubMed

    Rafferty, Anna N; LaMar, Michelle M; Griffiths, Thomas L

    2015-04-01

    Watching another person take actions to complete a goal and making inferences about that person's knowledge is a relatively natural task for people. This ability can be especially important in educational settings, where the inferences can be used for assessment, diagnosing misconceptions, and providing informative feedback. In this paper, we develop a general framework for automatically making such inferences based on observed actions; this framework is particularly relevant for inferring student knowledge in educational games and other interactive virtual environments. Our approach relies on modeling action planning: We formalize the problem as a Markov decision process in which one must choose what actions to take to complete a goal, where choices will be dependent on one's beliefs about how actions affect the environment. We use a variation of inverse reinforcement learning to infer these beliefs. Through two lab experiments, we show that this model can recover people's beliefs in a simple environment, with accuracy comparable to that of human observers. We then demonstrate that the model can be used to provide real-time feedback and to model data from an existing educational game.

  18. Manifold Warp Segmentation of Human Action.

    PubMed

    Liu, Shenglan; Feng, Lin; Liu, Yang; Qiao, Hong; Wu, Jun; Wang, Wei

    2017-03-08

    Human action segmentation is important for human action analysis, which is a highly active research area. Most segmentation methods are based on clustering or numerical descriptors, which are only related to data, and consider no relationship between the data and physical characteristics of human actions. Physical characteristics of human motions are those that can be directly perceived by human beings, such as speed, acceleration, continuity, and so on, which are quite helpful in detecting human motion segment points. We propose a new physical-based descriptor of human action by curvature sequence warp space alignment (CSWSA) approach for sequence segmentation in this paper. Furthermore, time series-warp metric curvature segmentation method is constructed by the proposed descriptor and CSWSA. In our segmentation method, descriptor can express the changes of human actions, and CSWSA is an auxiliary method to give suggestions for segmentation. The experimental results show that our segmentation method is effective in both CMU human motion and video-based data sets.

  19. On the Inclusion of Externally Controlled Actions in Action Planning

    ERIC Educational Resources Information Center

    Tsai, Jessica Chia-Chin; Knoblich, Gunther; Sebanz, Natalie

    2011-01-01

    According to ideomotor theories, perceiving action effects produced by others triggers corresponding action representations in the observer. We tested whether this principle extends to actions performed by externally controlled limbs and tools. Participants performed a go-no-go version of a spatial compatibility task in which their own actions…

  20. Dynamics of Social Interaction: Kinematic Analysis of a Joint Action.

    PubMed

    Moreau, Quentin; Galvan, Lucie; Nazir, Tatjana A; Paulignan, Yves

    2016-01-01

    Non-verbal social interaction between humans requires accurate understanding of the others' actions. The cognitivist approach suggests that successful interaction depends on the creation of a shared representation of the task, where the pairing of perceptive and motor systems of partners allows inclusion of the other's goal into the overarching representation. Activity of the Mirror Neurons System (MNS) is thought to be a crucial mechanism linking two individuals during a joint action through action observation. The construction of a shared representation of an interaction (i.e., joint action) depends upon sensorimotor cognitive processes that modulate the ability to adapt in time and space. We attempted to detect individuals' behavioral/kinematic change resulting in a global amelioration of performance for both subjects when a common representation of the action is built using a repetitive joint action. We asked pairs of subjects to carry out a simple task where one puts a base in the middle of a table and the other places a parallelepiped fitting into the base, the crucial manipulation being that participants switched roles during the experiment. We aimed to show that a full comprehension of a joint action is not an automatic process. We found that, before switching the interactional role, the participant initially placing the base orientated it in a way that led to an uncomfortable action for participants placing the parallelepiped. However, after switching roles, the action's kinematics by the participant who places the base changed in order to facilitate the action of the other. More precisely, our data shows significant modulation of the base angle in order to ease the completion of the joint action, highlighting the fact that a shared knowledge of the complete action facilitates the generation of a common representation. This evidence suggests the ability to establish an efficient shared representation of a joint action benefits from physically taking our

  1. Consciousness: individuated information in action.

    PubMed

    Jonkisz, Jakub

    2015-01-01

    Within theoretical and empirical enquiries, many different meanings associated with consciousness have appeared, leaving the term itself quite vague. This makes formulating an abstract and unifying version of the concept of consciousness - the main aim of this article -into an urgent theoretical imperative. It is argued that consciousness, characterized as dually accessible (cognized from the inside and the outside), hierarchically referential (semantically ordered), bodily determined (embedded in the working structures of an organism or conscious system), and useful in action (pragmatically functional), is a graded rather than an all-or-none phenomenon. A gradational approach, however, despite its explanatory advantages, can lead to some counterintuitive consequences and theoretical problems. In most such conceptions consciousness is extended globally (attached to primitive organisms or artificial systems), but also locally (connected to certain lower-level neuronal and bodily processes). For example, according to information integration theory (as introduced recently by Tononi and Koch, 2014), even such simple artificial systems as photodiodes possess miniscule amounts of consciousness. The major challenge for this article, then, is to establish reasonable, empirically justified constraints on how extended the range of a graded consciousness could be. It is argued that conscious systems are limited globally by the ability to individuate information (where individuated information is understood as evolutionarily embedded, socially altered, and private), whereas local limitations should be determined on the basis of a hypothesis about the action-oriented nature of the processes that select states of consciousness. Using these constraints, an abstract concept of consciousness is arrived at, hopefully contributing to a more unified state of play within consciousness studies itself.

  2. Consciousness: individuated information in action

    PubMed Central

    Jonkisz, Jakub

    2015-01-01

    Within theoretical and empirical enquiries, many different meanings associated with consciousness have appeared, leaving the term itself quite vague. This makes formulating an abstract and unifying version of the concept of consciousness – the main aim of this article –into an urgent theoretical imperative. It is argued that consciousness, characterized as dually accessible (cognized from the inside and the outside), hierarchically referential (semantically ordered), bodily determined (embedded in the working structures of an organism or conscious system), and useful in action (pragmatically functional), is a graded rather than an all-or-none phenomenon. A gradational approach, however, despite its explanatory advantages, can lead to some counterintuitive consequences and theoretical problems. In most such conceptions consciousness is extended globally (attached to primitive organisms or artificial systems), but also locally (connected to certain lower-level neuronal and bodily processes). For example, according to information integration theory (as introduced recently by Tononi and Koch, 2014), even such simple artificial systems as photodiodes possess miniscule amounts of consciousness. The major challenge for this article, then, is to establish reasonable, empirically justified constraints on how extended the range of a graded consciousness could be. It is argued that conscious systems are limited globally by the ability to individuate information (where individuated information is understood as evolutionarily embedded, socially altered, and private), whereas local limitations should be determined on the basis of a hypothesis about the action-oriented nature of the processes that select states of consciousness. Using these constraints, an abstract concept of consciousness is arrived at, hopefully contributing to a more unified state of play within consciousness studies itself. PMID:26283987

  3. Public affairs committee actions

    NASA Astrophysics Data System (ADS)

    The AGU Public Affairs Committee will create an ad hoc committee to consider possible AGU position statements concerning the effects of nuclear war.The action was taken at the May 31, 1983, meeting of the Committee at the AGU Spring Meeting in Baltimore. Present were Carroll Ann Hodges, Chairman, and members Thomas J. Ahrens, David Cauffman, Jared Cohon, Stamatios Krimigis, Robert Murphy, Raymond Roble, and George Shaw. Also attending were the current Congressional Fellow Arthur Weissman and SPR—Cosmic Rays Section Secretary Miriam Forman.

  4. Neurobiological actions of cysteamine

    SciTech Connect

    Brown, M.; Fisher, L.; Mason, R.T.; Rivier, J.; Vale, W.

    1985-06-01

    Somatostatin (SS)-related peptides act within discrete brain regions to inhibit adrenal epinephrine (E) secretion, to prevent hypothermia, and to produce hyperthermia. Depletion of brain concentrations of these SS-related peptides using cysteamine (CSH) or central administration of an SS receptor antagonist increases adrenal E secretion and impairs thermoregulation. These actions of CSH and the SS receptor antagonist are reversed by administration of SS into the central nervous system. These results support the hypothesis that endogenous brain SS-related peptides are involved in the regulation of adrenal E secretion and thermoregulation.

  5. 3RS action plan

    SciTech Connect

    Not Available

    1990-01-01

    The goal of the Solid Waste Interim Steering Committee (SWISC) process is to develop a long-term waste management system for the Greater Toronto Area (GTA), to be in place by 1996, which is environmentally, socially, economically and technically sound. This background report is being released to the public and member Regional Councils to facilitate input to the SWISC planning process. The report documents current reduction, reuse and recycling initiatives in the GTA, identifies opportunities for coordination and collaboration among the GTA communities, and develops an action plan for improving the effectiveness of the reduction, reuse and recycling efforts within the GTA.

  6. Developing an action concept inventory

    NASA Astrophysics Data System (ADS)

    McGinness, Lachlan P.; Savage, C. M.

    2016-06-01

    We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics. The ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises. We used a multistage iterative development cycle for incorporating expert and student feedback into successive revisions of the ACI. The student feedback, including think-aloud interviews, enabled us to identify their misconceptions about action physics.

  7. Hierarchical and multiple hand action representation using temporal postural synergies.

    PubMed

    Tessitore, G; Sinigaglia, C; Prevete, R

    2013-03-01

    The notion of synergy enables one to provide simplified descriptions of hand actions. It has been used in a number of different meanings ranging from kinematic and dynamic synergies to postural and temporal postural synergies. However, relatively little is known about how representing an action by synergies might take into account the possibility to have a hierarchical and multiple action representation. This is a key aspect for action representation as it has been characterized by action theorists and cognitive neuroscientists. Thus, the aim of the present paper is to investigate whether and to what extent a hierarchical and multiple action representation can be obtained by a synergy approach. To this purpose, we took advantage of representing hand action as a linear combination of temporal postural synergies (TPSs), but on the assumption that TPSs have a tree-structured organization. In a tree-structured organization, a hand action representation can involve a TPS only if the ancestors of the synergy in the tree are themselves involved in the action representation. The results showed that this organization is enough to force a multiple representation of hand actions in terms of synergies which are hierarchically organized.

  8. Untrained Chimpanzees (Pan troglodytes schweinfurthii) Fail to Imitate Novel Actions

    PubMed Central

    Tennie, Claudio; Call, Josep; Tomasello, Michael

    2012-01-01

    Background Social learning research in apes has focused on social learning in the technical (problem solving) domain - an approach that confounds action and physical information. Successful subjects in such studies may have been able to perform target actions not as a result of imitation learning but because they had learnt some technical aspect, for example, copying the movements of an apparatus (i.e., different forms of emulation learning). Methods Here we present data on action copying by non-enculturated and untrained chimpanzees when physical information is removed from demonstrations. To date, only one such study (on gesture copying in a begging context) has been conducted – with negative results. Here we have improved this methodology and have also added non-begging test situations (a possible confound of the earlier study). Both familiar and novel actions were used as targets. Prior to testing, a trained conspecific demonstrator was rewarded for performing target actions in view of observers. All but one of the tested chimpanzees already failed to copy familiar actions. When retested with a novel target action, also the previously successful subject failed to copy – and he did so across several contexts. Conclusion Chimpanzees do not seem to copy novel actions, and only some ever copy familiar ones. Due to our having tested only non-enculturated and untrained chimpanzees, the performance of our test subjects speak more than most other studies of the general (dis-)ability of chimpanzees to copy actions, and especially novel actions. PMID:22905102

  9. Collaborative Action Research: Historical Trends.

    ERIC Educational Resources Information Center

    Smulyan, Lisa

    This paper presents a historical overview of the use of action research in education and describes the basic assumptions and expectations that continue to characterize collaborative research projects today. Action research was initiated in the 1930's by Kurt Lewin and adapted by educators in the 1940's. Interest in action research declined between…

  10. Programming Tool-Use Actions

    ERIC Educational Resources Information Center

    Massen, Cristina; Prinz, Wolfgang

    2007-01-01

    When humans plan to execute a tool-use action, they can only specify the bodily movement parameters by taking into account the external target or goal of the tool-use action and the target-movement mapping implemented by the tool. In this study, the authors used the movement precuing method to investigate how people prepare for actions made with…

  11. Developing an Action Concept Inventory

    ERIC Educational Resources Information Center

    McGinness, Lachlan P.; Savage, C. M.

    2016-01-01

    We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics. The ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises. We used a multistage iterative development cycle for…

  12. Rethinking Actions: Implementation and Association

    PubMed Central

    Chatterjee, Anjan

    2015-01-01

    Action processing allows us to move through and interact with the world, as well as understand the movements performed by other people. In recent years, there has been increasing interest in the semantics of actions as differentiated from the semantics of objects. However, as the understanding of action semantics has evolved, it is evident that the existing literature conflates two senses of the word “action”—one that stems from studies of tool use and the other from event representation. In this paper, we suggest that this issue can be clarified by closely examining differences in how the human parietal and temporal cortices of the brain process action-related stimuli. By contrasting the posterior parietal cortex to the posterolateral temporal cortex, we characterize two complementary action systems in the human brain, each with its own specialization of function. We suggest that these two systems be referred to as the parietal Action Implementation System, and the posterolateral temporal Action Association System. While the fronto-parietal system is concerned primarily with how we perform actions, and simulate others’ actions, the temporal action system is more involved with processing actions from a third-person, conceptual standpoint. Recent work in cognitive neuroscience of perception and language, as well as the neuroanatomical organization of these brain regions support this distinction. We will discuss the implications of this work for cognition-, language-, and neuroscience-based action research. PMID:26352170

  13. Action Principle for Relativistic Magnetohydrodynamics

    NASA Astrophysics Data System (ADS)

    D'Avignon, Eric; Morrison, Philip; Pegoraro, Francesco

    2015-11-01

    A covariant action principle for ideal relativistic magnetohydrodynamics in terms of natural Eulerian field variables is given. This is done by generalizing the covariant Poisson bracket theory of Marsden et al., which uses a noncanonical bracket to implement constrained variations of an action functional. Various implications and extensions of this action principle are also discussed.

  14. Motor Execution Affects Action Prediction

    ERIC Educational Resources Information Center

    Springer, Anne; Brandstadter, Simone; Liepelt, Roman; Birngruber, Teresa; Giese, Martin; Mechsner, Franz; Prinz, Wolfgang

    2011-01-01

    Previous studies provided evidence of the claim that the prediction of occluded action involves real-time simulation. We report two experiments that aimed to study how real-time simulation is affected by simultaneous action execution under conditions of full, partial or no overlap between observed and executed actions. This overlap was analysed by…

  15. Action Research in Music Education.

    ERIC Educational Resources Information Center

    Conway, Colleen M.; Borst, James

    2001-01-01

    Provides background information on using action research in music education. Offers guidelines for teachers to help them do action research. Includes an example of how a music teacher conducted action research in which the teacher asked, "Why did [the students] continue vocal music from middle school to high school?" (CMK)

  16. Wave action power plant

    SciTech Connect

    Lucia, L.V.

    1982-03-16

    A wave action power plant powered by the action of water waves has a drive shaft rotated by a plurality of drive units, each having a lever pivotally mounted on and extending from said shaft and carrying a weight, in the form of a float, which floats on the waves and rocks the lever up and down on the shaft. A ratchet mechanism causes said shaft to be rotated in one direction by the weight of said float after it has been raised by wave and the wave has passed, leaving said float free to move downwardly by gravity and apply its full weight to pull down on the lever and rotate the drive shaft. There being a large number of said drive units so that there are always some of the weights pulling down on their respective levers while other weights are being lifted by waves and thereby causing continuous rotation of the drive shaft in one direction. The said levers are so mounted that they may be easily raised to bring the weights into a position wherein they are readily accessible for cleaning the bottoms thereof to remove any accumulation of barnacles, mollusks and the like. There is also provided means for preventing the weights from colliding with each other as they independently move up and down on the waves.

  17. Capillary action liquid chromatography.

    PubMed

    Zhang, Bo; Bergström, Edmund T; Goodall, David M; Myers, Peter

    2009-06-01

    Capillary action LC (caLC) is introduced as a technique using capillary action as the driving force to perform LC in capillary columns packed with HPLC type microparticulate materials. A dry packing method with centrifugal force was developed to prepare capillary columns in parallel (10 columns per 3 min) to support their disposable use in caLC. Using a digital microscope for real-time imaging and recording separations of components in a dye mixture, caLC was found to have flow characteristics similar to TLC. Based on the investigation of microparticulate HPLC silica gels of different size (1.5-10 microm) and a typical TLC grade irregular medium, Merck 60G silica, the van Deemter curves suggested molecular diffusion as the major contribution to band broadening in caLC. With Waters Xbridge 2.6 microm silica, plate heights down to 8.8 microm were obtained, comparable to those achievable in HPLC. Assisted by an image-processing method, the visual caLC separation was converted to a classical chromatogram for further data analysis and such a facility confirmed the observation of highly efficient bands.

  18. [Surgical approaches in rhinoplasty].

    PubMed

    Nguyen, P S; Duron, J-B; Bardot, J; Levet, Y; Aiach, G

    2014-12-01

    In the first step of rhinoplasty, the surgical approach will expose through different types of incisions and dissection planes the osteocartilaginous framework of the nasal pyramid prior to performing actions to reduce or increase the latter. This exposure can be performed by a closed approach or by an external approach--the choice depends on the type of nose and the habits of the surgeon. Far from being opposites, closed and external approaches are complementary and should be known and mastered by surgeons performing rhinoplasty.

  19. Incorporating gender, equity, and human rights into the action planning process: moving from rhetoric to action.

    PubMed

    Sridharan, Sanjeev; Maplazi, Joanna; Shirodkar, Apurva; Richardson, Emma; Nakaima, April

    2016-01-01

    Background Mainstreaming of gender, equity, and human rights (GER) is an important focus of the World Health Organization (WHO) and other UN organizations. This paper explores the role of action plans in mainstreaming GER. This paper is informed by a theory-driven evaluation lens. Design A theory of change framework explored the following seven dimensions of how action plans can implement mainstreaming of GER: awareness of the foundations of GER; understanding of context; planning to impact GER; implementation for GER; monitoring, evaluation, and learning; planning for sustainability; agenda setting and buy-in. The seven dimensions were used to analyze the action plans. Reviewers also explored innovations within each of the action plans for the seven dimensions. Results GER mainstreaming is more prominent in the foundation, background, and planning components of the plan but becomes less so along the theory of change including implementation; monitoring and evaluation; sustainability; and agenda setting and buy-in. Conclusions Our analysis demonstrates that much more can be done to incorporate GER considerations into the action planning process. Nine specific recommendations are identified for WHO and other organizations. A theory-driven approach as described in the paper is potentially helpful for developing clarity by which action plans can help with mainstreaming GER considerations.

  20. Incorporating gender, equity, and human rights into the action planning process: moving from rhetoric to action

    PubMed Central

    Sridharan, Sanjeev; Maplazi, Joanna; Shirodkar, Apurva; Richardson, Emma; Nakaima, April

    2016-01-01

    Background Mainstreaming of gender, equity, and human rights (GER) is an important focus of the World Health Organization (WHO) and other UN organizations. This paper explores the role of action plans in mainstreaming GER. This paper is informed by a theory-driven evaluation lens. Design A theory of change framework explored the following seven dimensions of how action plans can implement mainstreaming of GER: awareness of the foundations of GER; understanding of context; planning to impact GER; implementation for GER; monitoring, evaluation, and learning; planning for sustainability; agenda setting and buy-in. The seven dimensions were used to analyze the action plans. Reviewers also explored innovations within each of the action plans for the seven dimensions. Results GER mainstreaming is more prominent in the foundation, background, and planning components of the plan but becomes less so along the theory of change including implementation; monitoring and evaluation; sustainability; and agenda setting and buy-in. Conclusions Our analysis demonstrates that much more can be done to incorporate GER considerations into the action planning process. Nine specific recommendations are identified for WHO and other organizations. A theory-driven approach as described in the paper is potentially helpful for developing clarity by which action plans can help with mainstreaming GER considerations. PMID:27606968