Science.gov

Sample records for action establishes class

  1. 78 FR 65555 - Establishment of Class E Airspace; Salmon, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Salmon, ID AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E... the establishment of Class E en route airspace. Class E airspace designations are published...

  2. 78 FR 41838 - Establishment of Class E Airspace; Colt, AR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Colt, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace for the Colt,...

  3. 75 FR 65226 - Establishment of Class E Airspace; Bamberg, SC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... Register a notice of proposed rulemaking to establish Class E airspace at Bamberg, SC (75 FR 52654) Docket... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Bamberg, SC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  4. 77 FR 44120 - Establishment of Class E Airspace; Roundup, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Roundup, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  5. 76 FR 16530 - Establishment of Class E Airspace; Creighton, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Creighton, NE AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  6. 78 FR 33967 - Establishment of Class E Airspace; Captiva, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Captiva, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  7. 78 FR 41839 - Establishment of Class E Airspace; Presidio, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Presidio, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  8. 78 FR 65554 - Establishment of Class E Airspace; Rome, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Rome, OR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E...

  9. 76 FR 43822 - Establishment of Class E Airspace; Hearne, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Hearne, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  10. 76 FR 9220 - Establishment of Class E Airspace; Martinsville, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Martinsville, IN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  11. 78 FR 41837 - Establishment of Class E Airspace; Parkston, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Parkston, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  12. 77 FR 68067 - Establishment of Class E Airspace; Coaldale, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Coaldale, NV AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  13. 76 FR 80232 - Establishment of Class E Airspace; Oneonta, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Oneonta, AL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  14. 76 FR 43821 - Establishment of Class E Airspace; Ranger, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Ranger, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  15. 78 FR 38828 - Establishment of Class E Airspace; Captiva, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Captiva, FL AGENCY...: History On June 6, 2013, the FAA published a final rule, in the Federal Register establishing Class E... aeronautical data charting service, thereby making this action necessary. The Class E airspace designations...

  16. 75 FR 42 - Establishment of Class E Airspace; Spencer, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... October 19, 2009 (74 FR 53407), Docket No. FAA- 2009-0602; Airspace Docket No. 09-AEA-13. The FAA uses the... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Spencer, WV AGENCY... that establishes Class E Airspace at Spencer, WV. This action enhances the safety and...

  17. 77 FR 60660 - Proposed Establishment Class E Airspace; Kasigluk, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment Class E Airspace; Kasigluk, AK...: This action proposes to establish Class E airspace at Kasigluk Airport, Kasigluk, AK, to...

  18. 16 CFR 1025.18 - Class actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Class actions. 1025.18 Section 1025.18 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL RULES OF PRACTICE FOR ADJUDICATIVE PROCEEDINGS Pleadings, Form, Execution, Service of Documents § 1025.18 Class actions. (a) Prerequisites to a class action. One or more members of a class...

  19. 16 CFR 1025.18 - Class actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Class actions. 1025.18 Section 1025.18 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL RULES OF PRACTICE FOR ADJUDICATIVE PROCEEDINGS Pleadings, Form, Execution, Service of Documents § 1025.18 Class actions. (a) Prerequisites to a class action. One or more members of a class...

  20. 76 FR 60713 - Establishment of Class E Airspace; Bumpass, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Airspace at Bumpass, VA, to accommodate the new Standard Instrument Approach Procedures serving Lake Anna... establish Class E airspace at Bumpass, VA (76 FR 45479) Docket No. FAA-2011-0377. Interested parties were... for Lake Anna Airport. This action is necessary for the safety and management of IFR operations at...

  1. 36 CFR 805.5 - Typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROCEDURES FOR IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.5 Typical classes of action. (a) Section 1507.3(c)(2) (40 CFR 1507.3(c)(2)) in conjunction with § 1508.4 requires agencies to establish... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Typical classes of action....

  2. Oil and gas: Oilfield class actions

    SciTech Connect

    McArthur, J.B.

    1997-06-01

    The use of class actions is getting alot of attention in the oilfield. Plaintiffs have filed class actions challenging two of the most rooted industry practices, oil posted prices and deregulated natural gas affiliate deduction and charges. The classes will include tens or hundreds of thousands of plaintiffs and may transform two of the industry`s most settled practices. The emotions surrounding the class action risk obscuring the fact that it is an old and oft-used tool in oilfield litigation. The class action {open_quotes}provides a means by which, where a large group of persons are interested in a matter, one or more may sue or be sued as representatives of the class without needing to join every member of the class.{close_quotes} The procedure avoids waste by combining scattered disputes, even if some injured might sue individually, and it enables plaintiffs who could not afford to sue to be represented anyway. The lawyers draw their fees from any recovery. Almost all oilpatch class actions are brought to resolve a {open_quotes}common question{close_quotes} under Federal Rules of Civil Procedure 23(b)(3) or state counterparts. The rule`s {open_quotes}opt-out{close_quotes} provisions give class actions a tremendous boost because members stay in unless they take steps to get out. This article discusses present and future class actions.

  3. 36 CFR 805.5 - Typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROCEDURES FOR IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.5 Typical classes of action. (a) Section 1507.3(c)(2) (40 CFR 1507.3(c)(2)) in conjunction with § 1508.4 requires agencies to establish... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Typical classes of...

  4. 36 CFR 805.5 - Typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROCEDURES FOR IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.5 Typical classes of action. (a) Section 1507.3(c)(2) (40 CFR 1507.3(c)(2)) in conjunction with § 1508.4 requires agencies to establish... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Typical classes of...

  5. 36 CFR 805.5 - Typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROCEDURES FOR IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.5 Typical classes of action. (a) Section 1507.3(c)(2) (40 CFR 1507.3(c)(2)) in conjunction with § 1508.4 requires agencies to establish... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Typical classes of...

  6. 36 CFR 805.5 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROCEDURES FOR IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.5 Typical classes of action. (a) Section 1507.3(c)(2) (40 CFR 1507.3(c)(2)) in conjunction with § 1508.4 requires agencies to establish... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Typical classes of...

  7. A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action.

    PubMed

    Mignani, Serge; El Brahmi, Nabil; El Kazzouli, Saïd; Eloy, Laure; Courilleau, Delphine; Caron, Joachim; Bousmina, Mosto M; Caminade, Anne-Marie; Cresteil, Thierry; Majoral, Jean-Pierre

    2016-10-21

    The well-known diuretic Ethacrynic acid (EA, Edecrin), showing low anti-proliferative activities, was chemically modified at different positions. The new EA derivatives have been tested in vitro in anti-proliferative assays on both tumor KB (epidermal carcinoma) and leukemia HL60 (promyelocytic) cells suitable targets for anticancer activity. Reduction of the α-β double bond of EA completely abolished anti-cancer activities, whereas introduction of either 2-(4-substituted phenyl)ethanamine (series A) or 4-(4-substituted phenyl)piperazine (series B) moieties generated compounds showing moderate to strong anti-proliferative activities against human cancer cell lines. Several substitutions on the phenyl of these two moieties are tolerated. The mechanism of action of the EA derivatives prepared in this study is more complex than the inhibition of glutathione S-transferase π ascribed as unique effect to EA and might help to overcome tumor resistances. PMID:27448922

  8. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Typical classes of action. 408.6 Section 408.6... ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3... three typical classes of action for similar treatment under NEPA. These typical classes of action...

  9. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Typical classes of action. 408.6 Section 408.6... ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3... three typical classes of action for similar treatment under NEPA. These typical classes of action...

  10. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Typical classes of action. 408.6 Section 408.6... ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3... three typical classes of action for similar treatment under NEPA. These typical classes of action...

  11. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Typical classes of action. 408.6 Section 408.6... ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3... three typical classes of action for similar treatment under NEPA. These typical classes of action...

  12. 12 CFR 408.6 - Typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Typical classes of action. 408.6 Section 408.6... ENVIRONMENTAL POLICY ACT Eximbank Implementing Procedures § 408.6 Typical classes of action. (a) Section 1507.3... three typical classes of action for similar treatment under NEPA. These typical classes of action...

  13. Disability, disparate impact, and class actions.

    PubMed

    Stein, Michael Ashley; Waterstone, Michael E

    2006-12-01

    Following Title VII's enactment, group-based employment discrimination actions flourished due to disparate impact theory and the class action device. Courts recognized that subordination that defined a group's social identity was also sufficient legally to bind members together, even when relief had to be issued individually. Woven through these cases was a notion of panethnicity that united inherently unrelated groups into a common identity, for example, Asian Americans. Stringent judicial interpretation subsequently eroded both legal frameworks and it has become increasingly difficult to assert collective employment actions, even against discriminatory practices affecting an entire group. This deconstruction has immensely disadvantaged persons with disabilities. Under the Americans with Disabilities Act (ADA), individual employee claims to accommodate specific impairments, such as whether to install ramps or replace computer screens, have all but eclipsed a coherent theory of disability-based disparate impact law. Moreover, the class action device has been virtually nonexistent in disability discrimination employment cases. The absence of collective action has been especially harmful because the realm of the workplace is precisely where group-based remedies are needed most. Specifically, a crucial but overlooked issue in disability integration is the harder-to-reach embedded norms that require job and policy modifications. The Article argues that pandisability theory serves as an analogue to earlier notions of panethnicity and provides an equally compelling heuristic for determining class identity. It shows that pandisability undergirds ADA public service and public accommodation class actions in which individualized remedy assessments have been accepted as part of group-based challenges to social exclusion. The Article also demonstrates that this broader vision of collective action is consistent with the history underlying the class action device. Taking

  14. 39 CFR 775.5 - Classes of actions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 CFR 1508.27. (b) Actions requiring an environmental assessment. Classes of actions that will... 39 Postal Service 1 2014-07-01 2014-07-01 false Classes of actions. 775.5 Section 775.5 Postal... PROCEDURES § 775.5 Classes of actions. (a) Actions which normally require an environment impact...

  15. 39 CFR 775.5 - Classes of actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 CFR 1508.27. (b) Actions requiring an environmental assessment. Classes of actions that will... 39 Postal Service 1 2012-07-01 2012-07-01 false Classes of actions. 775.5 Section 775.5 Postal... PROCEDURES § 775.5 Classes of actions. (a) Actions which normally require an environment impact...

  16. 39 CFR 775.5 - Classes of actions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 CFR 1508.27. (b) Actions requiring an environmental assessment. Classes of actions that will... 39 Postal Service 1 2013-07-01 2013-07-01 false Classes of actions. 775.5 Section 775.5 Postal... PROCEDURES § 775.5 Classes of actions. (a) Actions which normally require an environment impact...

  17. 39 CFR 775.5 - Classes of actions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 CFR 1508.27. (b) Actions requiring an environmental assessment. Classes of actions that will... 39 Postal Service 1 2011-07-01 2011-07-01 false Classes of actions. 775.5 Section 775.5 Postal... PROCEDURES § 775.5 Classes of actions. (a) Actions which normally require an environment impact...

  18. 39 CFR 775.5 - Classes of actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 CFR 1508.27. (b) Actions requiring an environmental assessment. Classes of actions that will... 39 Postal Service 1 2010-07-01 2010-07-01 false Classes of actions. 775.5 Section 775.5 Postal... PROCEDURES § 775.5 Classes of actions. (a) Actions which normally require an environment impact...

  19. 75 FR 20773 - Establishment of Class E Airspace; Jackson, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... final rule with a request for comments in the Federal Register on December 7, 2009 (74 FR 63973), Docket... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Jackson, AL AGENCY... December 7, 2009 that establishes Class E airspace at Jackson Muni, Jackson, AL. DATES: Effective...

  20. 75 FR 4270 - Establishment of Class E Airspace; Saluda, SC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Saluda, SC... Register September 14, 2009 that establishes Class E Airspace at Saluda County Airport, Saluda, SC. DATES... (74 FR 46894), Docket No. FAA-2009-0603; Airspace Docket No. 09-ASO-16. The FAA uses the direct...

  1. 75 FR 4269 - Establishment of Class E Airspace; Clayton, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Clayton, GA AGENCY... September 14, 2009 that establishes Class E Airspace at Heaven's Landing Airport, Clayton, GA. DATES... (74 FR 46893), Docket No. FAA-2009-0605; Airspace Docket 09-ASO-19. The FAA uses the direct...

  2. 75 FR 4269 - Establishment of Class E Airspace; Hertford, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Hertford, NC AGENCY... September 14, 2009 that establishes Class E Airspace at Harvey Point Defense Testing Activity, Hertford, NC... (74 FR 46892), Docket No. FAA-2009-0705; Airspace Docket No. 09-ASO-25. The FAA uses the direct...

  3. 76 FR 39259 - Establishment of Class E Airspace; Brunswick, ME

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... with the date July 25, 2011. Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Brunswick, ME AGENCY... establishes Class E airspace at Brunswick Executive Airport, Brunswick, ME. DATES: The effective date is...

  4. 75 FR 4270 - Establishment of Class E Airspace; Tompkinsville, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Tompkinsville, KY AGENCY... September 14, 2009 that establishes Class E Airspace at Tompkinsville--Monroe County Airport, Tompkinsville... September 14, 2009 (74 FR 46890), Docket No. FAA-2009-0604; Airspace Docket No. 09-ASO-18. The FAA uses...

  5. 75 FR 4269 - Establishment of Class E Airspace; Lewisport, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Lewisport, KY... Register September 14, 2009 that establishes Class E Airspace at Hancock Co.--Ron Lewis Field, Lewisport... September 14, 2009 (74 FR 46896), Docket No. FAA-2009-0706; Airspace Docket No. 09-ASO-26. The FAA uses...

  6. 76 FR 2800 - Establishment of Class E Airspace; Lucin, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Lucin, UT AGENCY... establishes Class E en route domestic airspace for the Lucin VORTAC, Lucin, UT. DATES: Effective 0901...

  7. 29 CFR 1608.4 - Establishing affirmative action plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Establishing affirmative action plans. 1608.4 Section 1608... AFFIRMATIVE ACTION APPROPRIATE UNDER TITLE VII OF THE CIVIL RIGHTS ACT OF 1964, AS AMENDED § 1608.4 Establishing affirmative action plans. An affirmative action plan or program under this section shall...

  8. 7 CFR 3407.5 - Classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Classes of action. 3407.5 Section 3407.5 Agriculture... IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 3407.5 Classes of action. The following describes typical classes of action associated with NIFA programs and related activities: (a) Actions which normally do...

  9. 7 CFR 632.52 - Identifying typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Identifying typical classes of action. 632.52 Section... § 632.52 Identifying typical classes of action. (a) The RFO will analyze the environmental assessment of the proposed action to determine which of the following classes of action applies. This...

  10. 7 CFR 3407.5 - Classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Classes of action. 3407.5 Section 3407.5 Agriculture... IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 3407.5 Classes of action. The following describes typical classes of action associated with NIFA programs and related activities: (a) Actions which normally do...

  11. 7 CFR 3407.5 - Classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Classes of action. 3407.5 Section 3407.5 Agriculture... IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 3407.5 Classes of action. The following describes typical classes of action associated with NIFA programs and related activities: (a) Actions which normally do...

  12. 7 CFR 632.52 - Identifying typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Identifying typical classes of action. 632.52 Section... § 632.52 Identifying typical classes of action. (a) The RFO will analyze the environmental assessment of the proposed action to determine which of the following classes of action applies. This...

  13. 78 FR 78794 - Proposed Establishment of Class E Airspace; Flagstaff, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ...This action proposes to establish Class E airspace at the Flagstaff VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation aid, Flagstaff, AZ, to facilitate vectoring of Instrument Flight Rules (IFR) aircraft under control of Albuquerque Air Route Traffic Control Center (ARTCC). The FAA is proposing this action to enhance the safety and management of aircraft......

  14. 78 FR 6262 - Proposed Establishment of Class E Airspace; Immokalee, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ...This action proposes to establish Class E Airspace at Immokalee, FL, to accommodate the Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures at Big Cypress Airfield. This action would enhance the safety and airspace management of Instrument Flight Rules (IFR) operations at the...

  15. 78 FR 65239 - Proposed Establishment of Class E Airspace; Brevig Mission, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ...This action proposes to establish Class E airspace at Brevig Mission Airport, Brevig Mission, AK. Controlled airspace is necessary to accommodate aircraft using new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at the airport. The FAA is proposing this action to enhance the safety and management of aircraft operations at the...

  16. 76 FR 28382 - Proposed Establishment of Class E Airspace; Nephi, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ...This action proposes to establish Class E airspace at Nephi Municipal Airport, Nephi, UT. Controlled airspace is necessary to accommodate aircraft using a new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at Nephi Municipal Airport, Nephi, UT. The FAA is proposing this action to enhance the safety and management of aircraft operations at the......

  17. 78 FR 31430 - Proposed Establishment of Class E Airspace; Wagner, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...This action proposes to establish Class E airspace at Wagner, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Wagner Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  18. 78 FR 65237 - Proposed Establishment of Class E Airspace; Central, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ...This action proposes to establish Class E airspace at Central Airport, Central, AK. Controlled airspace is necessary to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at the airport. The FAA is proposing this action to enhance the safety and management of aircraft operations at Central Airport, Central,...

  19. 78 FR 25233 - Proposed Establishment of Class E Airspace; Mahnomen, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Mahnomen, MN. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Mahnomen County Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  20. 77 FR 71368 - Proposed Establishment of Class E Airspace; Tecumseh, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...This action proposes to establish Class E airspace at Tecumseh, NE. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Tecumseh Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  1. 78 FR 25232 - Proposed Establishment of Class E Airspace; Parkston, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Parkston, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Parkston Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  2. 78 FR 25234 - Proposed Establishment of Class E Airspace; Walker, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Walker, MN. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Walker Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  3. 78 FR 25231 - Proposed Establishment of Class E Airspace; Colt, AR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Colt, AR. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Delta Regional Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  4. 78 FR 49985 - Proposed Establishment of Class E Airspace; Sisseton, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ...This action proposes to establish Class E airspace at Sisseton, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Sisseton Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  5. 78 FR 25229 - Proposed Establishment of Class E Airspace; Stockton, KS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Stockton, KS. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Rooks County Regional Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  6. 77 FR 71365 - Proposed Establishment of Class E Airspace; Beeville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...This action proposes to establish Class E airspace at Beeville, TX. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Chase Field Industrial Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  7. 78 FR 65238 - Proposed Establishment of Class E Airspace; Eagle, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ...This action proposes to establish Class E airspace at Eagle Airport, Eagle, AK. Controlled airspace is necessary to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures developed for the airport. The FAA is proposing this action to enhance the safety and management of aircraft operations at Eagle Airport, Eagle,...

  8. 75 FR 26148 - Establishment of Class E Airspace; Homestead, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... needed for the Standard Instrument Approach Procedures (SIAPs) developed for Homestead General Aviation... airspace required to support the SIAPs for Homestead General Aviation Airport. Class E airspace extending... as it would establish Class E airspace Homestead General Aviation Airport, Homestead, FL. Lists...

  9. 78 FR 33965 - Establishment of Class E Airspace; Linton, ND

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Linton, ND... Class E airspace at Linton, ND. Controlled airspace is necessary to accommodate new Area...

  10. 76 FR 40598 - Establishment of Class E Airspace; Campbellton, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Campbellton, TX... Class E airspace for Campbellton, TX, to accommodate new Area Navigation (RNAV) Standard...

  11. 78 FR 25384 - Establishment of Class E Airspace; Immokalee, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Class E Airspace at Immokalee, FL, to accommodate the Area Navigation (RNAV) Global Positioning System... establish Class E airspace at Immokalee, FL (78 FR 6262) Docket No. FAA-2012-1051. Interested parties were... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  12. 77 FR 45240 - Establishment of Class E Airspace; Arcadia, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... Class E Airspace at Arcadia, FL, to accommodate the new Area Navigation (RNAV) Global Positioning System... establish Class E airspace at Oneonta, AL (77 FR 33685) Docket No. FAA-2012-0365. Interested parties were... rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...

  13. 23 CFR 771.115 - Classes of actions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... significantly affect the environment require an EIS (40 CFR 1508.27). The following are examples of actions that....118(d) for FTA actions. (c) Class III (EAs). Actions in which the significance of the...

  14. SADC establishes a regional action plan.

    PubMed

    Klouda, T

    1997-02-01

    The regional meeting held on AIDS strategy in Lilongwe, Malawi, in December, 1996, made important advances. The 12 countries of the SADC (Southern Africa Development Community) joined the European Union to institute a regional action plan for the reduction of susceptibility of people to HIV because of social, cultural, and environmental factors; the vulnerability of people with HIV infection to social and other difficulties; and the vulnerability of institutions because of the foregoing impacts. At the conference the issues explored were employment, mining, medical drugs, education, and tourism. An employment charter was seen as crucial for the success of AIDS and workplace activities. Facilitation of travel across borders was important for the reduction of susceptibility to HIV infection. Enhancement of regional policies for essential drugs was vital for drugs for the treatment of AIDS. The clarification of the regional role was critical for regional support of national action (strengthening technical and institutional capacities) and for regional joint action such as studies on research, harmonization of data collection on HIV/AIDS; organization of training; development of information and education on HIV/AIDS; facilitation of manufacturing of drugs and condoms; and the development of a regional information and education program about HIV/AIDS. The conference also clarified HIV/AIDS programs in relation to other health and socioeconomic problems. PMID:12292055

  15. Establishment of Class e1 Mass Standard of 50 kg

    NASA Astrophysics Data System (ADS)

    Yao, Hong; Wang, Jian; Ding, Jingan; Zhong, Ruilin; Ren, Xiaoping

    Because of the equipment limit, the dissemination of large mass has been realized by a large amount of higher class of 20 kg weights since 1950s in China. But with improvement of the technique and customer's requirements, it is necessary to establish the mass standard of 50 kg weight. In 1990s, mass standard laboratory has set up Class E1 weight sets from 20 kg to 1 mg. To extend the mass capacity up to 50 kg of Class E1, it is not only to produce Class E1 50 kg weight and import a mass comparator, but also need to lift the heavy weight from weight box to balance receptor safely. Up to now, the mass comparator has been installed in Hepingli campus of NIM. Two pieces of Class E1 50 kg weights are determined by combination weighing method. A lifting device has been mounted close to the mass comparator in order to move the 50 kg easily.

  16. 7 CFR 3407.5 - Classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Classes of action. 3407.5 Section 3407.5 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION... action. The following describes typical classes of action associated with CSREES programs and...

  17. 78 FR 40076 - Proposed Establishment and Modification of Class E Airspace; Oakland, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... (NPRM). SUMMARY: This action proposes to establish Class E airspace extending upward from 700 feet...

  18. 78 FR 20846 - Proposed Establishment of Class E Airspace; Leesburg, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959...: This action proposes to establish Class E surface airspace at Leesburg, VA, to aid Potomac TRACON...

  19. 77 FR 17363 - Proposed Establishment of Class E Airspace; West Memphis, AR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3...). SUMMARY: This action proposes to establish Class E airspace at West Memphis, AR. Separation of...

  20. 76 FR 66871 - Proposed Establishment of Class E Airspace; Inverness, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389...: This action proposes to establish Class E Airspace at Inverness, FL, to accommodate new Area...

  1. 76 FR 49388 - Proposed Establishment of Class E Airspace; Tatitlek, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by...: This action proposes to establish Class E airspace at Tatitlek, AK. The creation of a...

  2. 78 FR 54415 - Proposed Establishment of Class E Airspace; Ennis, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation...). SUMMARY: This action proposes to establish Class E airspace at Ennis- Big Sky Airport, Ennis,...

  3. 75 FR 44727 - Proposed Revocation and Establishment of Class E Airspace; St. George, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... action also would establish Class E surface airspace within a 4.5-mile radius of the new St. George...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation...

  4. 77 FR 18103 - Establishment of Class E Airspace; Piseco, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... rulemaking (NPRM) to establish Class E airspace 700 feet above the surface, at Piseco, NY (76 FR 77451.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  5. 75 FR 12161 - Establishment of Class E Airspace; Marianna, AR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Marianna, AR...

  6. 76 FR 65944 - Establishment of Class E Airspace; Tatitlek, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... to establish Class E airspace at Tatitlek, AK (76 FR 49388). Interested parties were invited to... not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  7. 78 FR 72009 - Establishment of Class E Airspace; Star, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Federal Register a notice of proposed rulemaking to establish Class E airspace at Star, NC (78 FR 54413... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  8. 75 FR 26150 - Establishment of Class E Airspace; Williamson, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ...: ] Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Williamson,...

  9. 76 FR 42471 - Establishment of Class E Airspace; Brunswick, ME

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... rule FR Doc 2011-16783, on page 39259 in the Federal Register of July 6, 2011 (76 FR 39259), make the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Brunswick, ME...

  10. 75 FR 79295 - Establishment of Class E Airspace; Crewe, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... Federal Register a notice of proposed rulemaking to establish Class E airspace at Crewe, VA (75 FR 57215...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  11. 75 FR 41076 - Establishment of Class E Airspace; Monterey, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Monterey, CA AGENCY... E airspace at Monterey, CA, to accommodate aircraft using a new Area Navigation (RNAV)...

  12. 78 FR 67296 - Establishment of Class D Airspace; Mesquite, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... establish Class D airspace for Mesquite Metro Airport, Mesquite, TX (78 FR 48842) Docket No. FAA-2012- 0580...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  13. 76 FR 45177 - Establishment of Class E Airspace; Nephi, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... airspace at Nephi UT, to accommodate aircraft using new Area Navigation (RNAV) Global Positioning System... proposed rulemaking to establish Class E airspace at Nephi, UT (76 FR 28382). Interested parties were... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  14. 76 FR 14802 - Establishment of Class E Airspace; Lancaster, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... Airspace at Lancaster, NH, to accommodate a new Area Navigation Global Positioning System RNAV special... establish Class E airspace at Lancaster, NH (75 FR 81517). Interested parties were invited to participate in... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  15. 78 FR 61179 - Establishment of Class E Airspace; Comanche, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Comanche, TX...

  16. 7 CFR 632.52 - Identifying typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... significant environmental issues. (3) Actions excluded from the EIS requirements. Those actions taken to... § 632.52 Identifying typical classes of action. (a) The RFO will analyze the environmental assessment of....12. These actions are determined by a limited environmental assessment that reasonably identifies...

  17. 7 CFR 632.52 - Identifying typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... significant environmental issues. (3) Actions excluded from the EIS requirements. Those actions taken to... § 632.52 Identifying typical classes of action. (a) The RFO will analyze the environmental assessment of....12. These actions are determined by a limited environmental assessment that reasonably identifies...

  18. 7 CFR 632.52 - Identifying typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... significant environmental issues. (3) Actions excluded from the EIS requirements. Those actions taken to... § 632.52 Identifying typical classes of action. (a) The RFO will analyze the environmental assessment of....12. These actions are determined by a limited environmental assessment that reasonably identifies...

  19. 78 FR 57545 - Proposed Establishment of Class D Airspace and Class E Airspace; Laguna AAF, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Proposed Establishment of Class D Airspace and Class E Airspace; Laguna AAF, AZ AGENCY: Federal...

  20. 78 FR 34552 - Modification of Class D and Class E Airspace and Establishment of Class E Airspace; Pasco, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... establish Class E surface airspace and modify Class D and E airspace at Pasco, WA (78 FR 18259). Interested... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034...), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2....

  1. 41 CFR 51-7.4 - Typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ENVIRONMENTAL ANALYSIS § 51-7.4 Typical classes of action. (a) 40 CFR 1507.3(b)(2) in conjunction with 40 CFR..., by referring to 40 CFR 1508.27, whether an EIS or an environmental assessment is required where: (1... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Typical classes...

  2. 41 CFR 51-7.4 - Typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL ANALYSIS § 51-7.4 Typical classes of action. (a) 40 CFR 1507.3(b)(2) in conjunction with 40 CFR..., by referring to 40 CFR 1508.27, whether an EIS or an environmental assessment is required where: (1... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Typical classes of...

  3. 41 CFR 51-7.4 - Typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ENVIRONMENTAL ANALYSIS § 51-7.4 Typical classes of action. (a) 40 CFR 1507.3(b)(2) in conjunction with 40 CFR..., by referring to 40 CFR 1508.27, whether an EIS or an environmental assessment is required where: (1... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Typical classes of...

  4. 41 CFR 51-7.4 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL ANALYSIS § 51-7.4 Typical classes of action. (a) 40 CFR 1507.3(b)(2) in conjunction with 40 CFR..., by referring to 40 CFR 1508.27, whether an EIS or an environmental assessment is required where: (1... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Typical classes of...

  5. 41 CFR 51-7.4 - Typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ENVIRONMENTAL ANALYSIS § 51-7.4 Typical classes of action. (a) 40 CFR 1507.3(b)(2) in conjunction with 40 CFR..., by referring to 40 CFR 1508.27, whether an EIS or an environmental assessment is required where: (1... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Typical classes...

  6. Semantic Similarity and Grammatical Class in Naming Actions

    ERIC Educational Resources Information Center

    Vigliocco, Gabriella; Vinson, David P.; Siri, Simona

    2005-01-01

    Italian speakers were asked to name pictures of actions (e.g. "bere", to drink). Pictures were presented at the same time as distracter words that were semantically related or unrelated to the picture names, and were of the same or different grammatical class (verbs or nouns). Half of the participants named the actions as verbs in citation form,…

  7. Assessing a New Approach to Class-Based Affirmative Action

    ERIC Educational Resources Information Center

    Gaertner, Matthew N.

    2011-01-01

    In November, 2008, Colorado and Nebraska voted on amendments that sought to end race-based affirmative action at public universities. In anticipation of the vote, Colorado's flagship public institution--The University of Colorado at Boulder (CU)--explored statistical approaches to support class-based affirmative action. This paper details CU's…

  8. Assessing a New Approach to Class-Based Affirmative Action

    ERIC Educational Resources Information Center

    Gaertner, Matthew Newman

    2011-01-01

    In November, 2008, Colorado and Nebraska voted on amendments that sought to end race-based affirmative action at public universities in those states. In anticipation of the vote, the University of Colorado at Boulder (CU) explored statistical approaches to support class-based (i.e., socioeconomic) affirmative action. This dissertation introduces…

  9. 76 FR 70919 - Proposed Amendment of Class D and Class E Airspace, and Establishment of Class E Airspace...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... would establish Class E En Route Domestic airspace to facilitate vectoring of Instrument Flight...

  10. Social Class and Social Action: The Middle-Class Bias of Democratic Theory in Education

    ERIC Educational Resources Information Center

    Schutz, Aaron

    2008-01-01

    Background: This article examines the emergence of the middle and working classes in America and describes key characteristics of these cultures as they manifest themselves today. It then explores the effects of social class on our conceptions of democracy. Purpose: To help educators understand the relationship between social action strategies and…

  11. 78 FR 33015 - Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ...This action proposes to amend Class D airspace at Waco, TX, by separating the Class D airspace at Waco Regional Airport from the Class D airspace at TSTC-Waco Airport. The FAA is taking this action to alleviate multiple air traffic controllers handling the same airspace and for the safety and management of Instrument Flight Rules (IFR) operations for standard instrument approach procedures at......

  12. 28 CFR 61.5 - Typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Department of Justice shall independently determine whether an EIS or an environmental assessment is required... 61.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT Implementing Procedures § 61.5 Typical classes of action. (a) The...

  13. 28 CFR 61.5 - Typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Department of Justice shall independently determine whether an EIS or an environmental assessment is required... 61.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT Implementing Procedures § 61.5 Typical classes of action. (a) The...

  14. 28 CFR 61.5 - Typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Department of Justice shall independently determine whether an EIS or an environmental assessment is required... 61.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT Implementing Procedures § 61.5 Typical classes of action. (a) The...

  15. 28 CFR 61.5 - Typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Department of Justice shall independently determine whether an EIS or an environmental assessment is required... 61.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT Implementing Procedures § 61.5 Typical classes of action. (a) The...

  16. 28 CFR 61.5 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Department of Justice shall independently determine whether an EIS or an environmental assessment is required... 61.5 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT Implementing Procedures § 61.5 Typical classes of action. (a) The...

  17. 50 CFR 530.3 - Typical classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Typical classes of action. 530.3 Section 530.3 Wildlife and Fisheries MARINE MAMMAL COMMISSION COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL... marine mammal protection and conservation for which an EIS or environmental assessment is either...

  18. 50 CFR 530.3 - Typical classes of action.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Typical classes of action. 530.3 Section 530.3 Wildlife and Fisheries MARINE MAMMAL COMMISSION COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL... marine mammal protection and conservation for which an EIS or environmental assessment is either...

  19. 50 CFR 530.3 - Typical classes of action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Typical classes of action. 530.3 Section 530.3 Wildlife and Fisheries MARINE MAMMAL COMMISSION COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL... marine mammal protection and conservation for which an EIS or environmental assessment is either...

  20. 50 CFR 530.3 - Typical classes of action.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Typical classes of action. 530.3 Section 530.3 Wildlife and Fisheries MARINE MAMMAL COMMISSION COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL... marine mammal protection and conservation for which an EIS or environmental assessment is either...

  1. 50 CFR 530.3 - Typical classes of action.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Typical classes of action. 530.3 Section 530.3 Wildlife and Fisheries MARINE MAMMAL COMMISSION COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL... marine mammal protection and conservation for which an EIS or environmental assessment is either...

  2. 75 FR 57847 - Establishment of Class E Airspace; Homestead, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... Approach Procedures (SIAPs) developed for Homestead General Aviation Airport. This action enhances the... to support the SIAPs developed for Homestead General Aviation Airport. This action is necessary for... Homestead, FL Homestead General Aviation Airport, FL (Lat. 25 29'57'' N., long. 80 33'15'' W.) That...

  3. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Establishment of rates and classes of competitive... classes of competitive products of general applicability. This section relates to changes in rates or classes of competitive products of general applicability. (a) Prior to establishing changes in rates...

  4. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Establishment of rates and classes of competitive... classes of competitive products of general applicability. This section relates to changes in rates or classes of competitive products of general applicability. (a) Prior to establishing changes in rates...

  5. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Establishment of rates and classes of competitive... classes of competitive products of general applicability. This section relates to changes in rates or classes of competitive products of general applicability. (a) Prior to establishing changes in rates...

  6. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Establishment of rates and classes of competitive... classes of competitive products of general applicability. This section relates to changes in rates or classes of competitive products of general applicability. (a) Prior to establishing changes in rates...

  7. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment of rates and classes of competitive... classes of competitive products of general applicability. This section relates to changes in rates or classes of competitive products of general applicability. (a) Prior to establishing changes in rates...

  8. 76 FR 59503 - Establishment of Class E Airspace; Lebanon, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... proposed rulemaking to amend Class E airspace 700 feet above the surface, at Lebanon, PA (76 FR 39038... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  9. 76 FR 30534 - Establishment of Class E Airspace; Kenbridge, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... proposed rulemaking to amend Class E airspace 700 feet above the surface, at Kenbridge, VA (75 FR 14823...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  10. 78 FR 1750 - Establishment of Class E Airspace; Princeton, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Airspace at Princeton, KY, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS... Class E airspace at Princeton, KY (77 FR 64919) Docket No. FAA-2011-1444. Subsequent to publication... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  11. 76 FR 14800 - Establishment of Class E Airspace; Wolfeboro, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... Airspace at Wolfeboro, NH, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS... Class E airspace at Wolfeboro, NH (75 FR 81518). Interested parties were invited to participate in this... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  12. 76 FR 64234 - Establishment of Class E Airspace; Palmyra, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... airspace at Palmyra, PA, to accommodate new Area Navigation (RNAV) Global Positioning System (GPS) Standard... (NPRM) to amend Class E airspace 700 feet above the surface, at Palmyra, PA (76 FR 49390). Interested... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  13. 76 FR 55232 - Establishment of Class E Airspace; Copperhill, TN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... Airspace at Copperhill, TN, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS... the controlled airspace required to ] accommodate the new Area Navigation (RNAV) Global Positioning... Class E airspace at Copperhill, TN (76 FR 35370) Docket No. FAA-2011-0402. Interested parties...

  14. Regulation of androgen action during establishment of pregnancy.

    PubMed

    Gibson, Douglas A; Simitsidellis, Ioannis; Saunders, Philippa T K

    2016-07-01

    During the establishment of pregnancy, the ovarian-derived hormones progesterone and oestradiol regulate remodelling of the endometrium to promote an environment that is able to support and maintain a successful pregnancy. Decidualisation is characterised by differentiation of endometrial stromal cells that secrete growth factors and cytokines that regulate vascular remodelling and immune cell influx. This differentiation process is critical for reproduction, and inadequate decidualisation is implicated in the aetiology of pregnancy disorders such as foetal growth restriction and preeclampsia. In contrast to progesterone and oestradiol, the role of androgens in regulating endometrial function is poorly understood. Androgen receptors are expressed in the endometrium, and androgens are reported to regulate both the transcriptome and the secretome of endometrial stromal cells. In androgen-target tissues, circulating precursors are activated to mediate local effects, and recent studies report that steroid concentrations detected in endometrial tissue are distinct to those detected in the peripheral circulation. New evidence suggests that decidualisation results in dynamic changes in the expression of androgen biosynthetic enzymes, highlighting a role for pre-receptor regulation of androgen action during the establishment of pregnancy. These results suggest that such enzymes could be future therapeutic targets for the treatment of infertility associated with endometrial dysfunction. In conclusion, these data support the hypothesis that androgens play a beneficial role in regulating the establishment and maintenance of pregnancy. Future studies should be focussed on investigating the safety and efficacy of androgen supplementation with the potential for utilisation of novel therapeutics, such as selective androgen receptor modulators, to improve reproductive outcomes in women. PMID:27067639

  15. Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts.

    PubMed

    Bryant, Laura A; Fanelli, Rossana; Cobb, Alexander J A

    2016-01-01

    Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the different spacing between the functional groups, can control enantioselectivity where other organocatalysts have failed. In the main, this review covers the highlights from the last five years and attempts to show the diversity of reactions that these systems can control. It is hoped that chemists developing asymmetric methodologies will see the value in adding these easily accessible, but underused organocatalysts to their screens. PMID:27340439

  16. Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

    PubMed Central

    Bryant, Laura A; Fanelli, Rossana

    2016-01-01

    Summary Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the different spacing between the functional groups, can control enantioselectivity where other organocatalysts have failed. In the main, this review covers the highlights from the last five years and attempts to show the diversity of reactions that these systems can control. It is hoped that chemists developing asymmetric methodologies will see the value in adding these easily accessible, but underused organocatalysts to their screens. PMID:27340439

  17. 75 FR 12974 - Establishment of Class E Airspace; Hailey, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... Register a notice of proposed rulemaking to establish additional controlled airspace at Hailey, ID (74 FR... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565,...

  18. 78 FR 31397 - Establishment of Class E Airspace; Cherokee, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... proposed rulemaking (NPRM) to establish controlled airspace at Cherokee, WY (78 FR 14032). Interested...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  19. 78 FR 17084 - Establishment of Class E Airspace; Wilbur, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... proposed rulemaking (NPRM) to establish controlled airspace at Wilbur, WA (77 FR 75597). Interested parties... ``significant rule'' under DOT Regulatory Policies and Procedures (44 ] FR 11034; February 26, 1979); and (3..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation...

  20. 77 FR 38476 - Establishment of Class E Airspace; Eureka, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... notice of proposed rulemaking to establish controlled airspace at Eureka, NV (77 FR 21509). Interested... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  1. 75 FR 63708 - Establishment of Class E Airspace; Kalaupapa, HI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... Federal Register a notice of proposed rulemaking to establish controlled airspace at Kalaupapa, HI (75 FR... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  2. 76 FR 18041 - Establishment of Class E Airspace; Kahului, HI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... establish controlled airspace at Kahului, HI (76 FR 3571). Interested parties were invited to participate in... a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  3. 78 FR 67298 - Establishment of Class E Airspace; Ennis, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... rulemaking (NPRM) to establish controlled airspace at Ennis, MT (78 FR 54415). Interested parties were... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2....

  4. 76 FR 41397 - Establishment of Class E Airspace; Florence, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... Register a notice of proposed rulemaking to establish controlled airspace at Florence, OR (76 FR 21269... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  5. 78 FR 59805 - Establishment of Class E Airspace; Cody, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ...) to establish controlled airspace at Cody, WY (78 FR 40078). Interested parties were invited to... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  6. 78 FR 59807 - Establishment of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... proposed rulemaking (NPRM) to establish controlled airspace at Glasgow, MT (78 FR 41337). Interested...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  7. 78 FR 34556 - Establishment of Class E Airspace; Tobe, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... proposed rulemaking (NPRM) to establish controlled airspace at Tobe, CO (78 FR 18264). Interested parties... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  8. 78 FR 34555 - Establishment of Class E Airspace; Gillette, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... proposed rulemaking (NPRM) to establish controlled airspace at Gillette, WY (78 FR 18266). Interested...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  9. 76 FR 45177 - Establishment of Class E Airspace; Kayenta, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at Kayenta Airport... Federal Register a notice of proposed rulemaking to establish controlled airspace at Kayenta, AZ (76 FR... a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26,...

  10. 76 FR 64233 - Amendment of Class D and Class E Airspace and Establishment of Class E Airspace; Casper, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ..., published on August 25, 2011 (76 FR 53048), amends Class D airspace, Class E surface airspace, Class E..., the Class E airspace descriptions as published in the Federal Register of August 25, 2011 (76 FR 53048) (FR Doc. 2011-21663) for Natrona County International Airport, Casper, WY, is corrected under...

  11. 78 FR 33965 - Establishment of Class E Airspace; Immokalee-Big Cypress Airfield, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ..., establishes Class E airspace at Big Cypress Airfield, Immokalee, FL (78 FR 25384). Subsequent to publication..., 2013 (78 FR 25384) FR Doc. 2013-10214, is corrected to read ``. . . Immokalee-Big Cypress, FL''; and in... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Immokalee-Big...

  12. 76 FR 52596 - Proposed Establishment of Class C Airspace for Long Beach, CA; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class C Airspace for Long Beach... airspace users and others, concerning a proposal to establish Class C airspace at Long Beach, CA. The... on or before December 12, 2011. ADDRESSES: The meetings will be held at the Holiday Inn Long...

  13. 75 FR 20774 - Establishment of Class E Airspace; Fort A.P. Hill, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... final rule with a request for comments in the Federal Register on December 7, 2009 (74 FR 63974), Docket... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Fort A.P. Hill, VA... Register December 7, 2009 that establishes Class E airspace at Fort A.P. Hill, VA. DATES: Effective...

  14. 75 FR 32268 - Establishment of Class E Airspace; Panama City, Tyndall AFB, FL.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ... direct final rule with a request for comments in the Federal Register on April 1, 2010 (75 FR 16331... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Panama City, Tyndall AFB... Federal Register April 1, 2010 that establishes Class E airspace at Tyndall AFB, Panama City, FL....

  15. 75 FR 20774 - Establishment of Class E Airspace; Mountain City, TN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... FR 63976), Docket No. FAA-2009-0061; Airspace Docket No. 09-ASO-10. The FAA uses the direct final... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Mountain City, TN AGENCY... December 7, 2009 that establishes Class E airspace at Johnson County Airport, Mountain City, TN....

  16. 78 FR 58158 - Establishment of Class D Airspace; Bryant AAF, Anchorage, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... Register establishing Class D airspace at Bryant AAF, Anchorage, AK (78 FR 48299, August 8, 2013). In the..., as published in the Federal Register on August 8, 2013 (78 FR 48299), FR Doc. 2013-18866, are... Federal Aviation Administration 14 CFR Part 71 Establishment of Class D Airspace; Bryant AAF,...

  17. Social class affects Mu-suppression during action observation.

    PubMed

    Varnum, Michael E W; Blais, Chris; Brewer, Gene A

    2016-08-01

    Socioeconomic status (SES) has been linked to differences in the degree to which people are attuned to others. Those who are lower in SES also tend to be more interpersonally attuned. However, to date, this work has not been demonstrated using neural measures. In the present electroencephalogram study, we found evidence that lower SES was linked to stronger Mu-suppression during action observation. This finding adds to the growing literature on factors that affect Mu-suppression and suggests that the mirror neuron system may be influenced by one's social class. PMID:26458132

  18. 29 CFR 1608.4 - Establishing affirmative action plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... three elements: a reasonable self analysis; a reasonable basis for concluding action is appropriate; and reasonable action. (a) Reasonable self analysis. The objective of a self analysis is to determine whether... analysis. The employer may utilize techniques used in order to comply with Executive Order 11246,...

  19. 76 FR 35369 - Proposed Establishment of Class D and Amendment of Class E Airspace; Los Angeles, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by reference in 14 CFR... aircraft operations at the airport. This action also would edit Class E airspace by adding the...

  20. Energy Master dealers mull class action: overpricing, bad support charged

    SciTech Connect

    Schwartz, R.

    1982-04-19

    Thirteen disgruntled Energy Master Inc. (EMI) dealers may take out a class-action suit against the firm and World Wide Energy Systems Inc., both based in Atlanta, because of alleged overpricing, poor service practices, and misrepresentations. EMI was organized in 1977 by persons who have since served prison terms for unrelated mail fraud, but the new management blames dealer unhappiness on poor selling efforts. The company has increased dealer training, but cannot make up for all the problems dating from past management. World Wide Energy Systems denies any connection with economic prices, and some dealers see no cause to join in the suit. Dealers complain, however, that their background is inadequate for the technical requirements of handling the systems. (DCK)

  1. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source...

  2. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source...

  3. 78 FR 72007 - Establishment of Class E Airspace; McConnellsburg, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Class E Airspace at McConnellsburg, PA, to accommodate a new Area Navigation (RNAV) Global Positioning... proposed rulemaking (NPRM) to establish Class E airspace at McConnellsburg, PA, (78 FR 48081) Docket No... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  4. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source...

  5. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source...

  6. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source...

  7. 78 FR 46497 - Amendment of Class D and E Airspace, and Establishment of Class E Airspace; Oceana NAS, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... airspace, and establish Class E airspace at Oceana Naval Air Station, (NAS), VA, (78 FR 21084). Interested... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  8. 78 FR 72006 - Establishment of Class D Airspace and Class E Airspace; Laguna AAF, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Register a notice of proposed rulemaking (NPRM) to establish controlled airspace at Laguna AAF, AZ (78 FR... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a regulatory evaluation... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR,...

  9. 78 FR 2879 - Establishment of Class D and Class E Airspace; Camp Guernsey, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... establish controlled airspace at Camp Guernsey Airport, Camp Guernsey, WY (77 FR 56174). Interested parties... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2....

  10. 7 CFR 1940.319 - Completing environmental assessments for Class I actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) An important element of this assessment is to determine if the action affects an environmental... as the action having more than minimal impacts and the environmental assessment format for a Class II... for that impact, as specified in the environmental assessment format for a Class II action. See §...

  11. 7 CFR 1940.319 - Completing environmental assessments for Class I actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) An important element of this assessment is to determine if the action affects an environmental... as the action having more than minimal impacts and the environmental assessment format for a Class II... for that impact, as specified in the environmental assessment format for a Class II action. See §...

  12. 7 CFR 1940.319 - Completing environmental assessments for Class I actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) An important element of this assessment is to determine if the action affects an environmental... as the action having more than minimal impacts and the environmental assessment format for a Class II... for that impact, as specified in the environmental assessment format for a Class II action. See §...

  13. 7 CFR 1940.319 - Completing environmental assessments for Class I actions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) An important element of this assessment is to determine if the action affects an environmental... as the action having more than minimal impacts and the environmental assessment format for a Class II... for that impact, as specified in the environmental assessment format for a Class II action. See §...

  14. 7 CFR 1940.319 - Completing environmental assessments for Class I actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) An important element of this assessment is to determine if the action affects an environmental... as the action having more than minimal impacts and the environmental assessment format for a Class II... for that impact, as specified in the environmental assessment format for a Class II action. See §...

  15. 75 FR 63709 - Revocation of Class C Airspace, Establishment of Class D Airspace, and Modification of Class E...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... area and the 700 foot Class E airspace area at Columbus, GA (75 FR 27670). Interested parties were... Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR,...

  16. 16 CFR 1009.8 - Policy on establishing priorities for Commission action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Policy on establishing priorities for Commission action. 1009.8 Section 1009.8 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL GENERAL STATEMENTS OF POLICY OR INTERPRETATION § 1009.8 Policy on establishing priorities for Commission action. (a) This document states the...

  17. 16 CFR 1009.8 - Policy on establishing priorities for Commission action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Policy on establishing priorities for Commission action. 1009.8 Section 1009.8 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL GENERAL STATEMENTS OF POLICY OR INTERPRETATION § 1009.8 Policy on establishing priorities for Commission action. (a) This document states the...

  18. 16 CFR 1009.8 - Policy on establishing priorities for Commission action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Policy on establishing priorities for Commission action. 1009.8 Section 1009.8 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL GENERAL STATEMENTS OF POLICY OR INTERPRETATION § 1009.8 Policy on establishing priorities for Commission action. (a) This document states the...

  19. 16 CFR 1009.8 - Policy on establishing priorities for Commission action.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Policy on establishing priorities for Commission action. 1009.8 Section 1009.8 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL GENERAL STATEMENTS OF POLICY OR INTERPRETATION § 1009.8 Policy on establishing priorities for Commission action. (a) This document states the...

  20. 27 CFR 19.913 - Action on applications to establish small plants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Action on applications to establish small plants. 19.913 Section 19.913 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Fuel Use Permits § 19.913 Action on applications to establish small plants. (a) Receipt by...

  1. 37 CFR 3.73 - Establishing right of assignee to take action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... assignee to take action. 3.73 Section 3.73 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... by Assignee § 3.73 Establishing right of assignee to take action. (a) The inventor is presumed to be..., unless there is an assignment. (b)(1) In order to request or take action in a patent or trademark...

  2. 77 FR 9839 - Amendment of Class D and Class E Airspace, and Establishment of Class E Airspace; Bozeman, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... rulemaking to amend and establish controlled airspace at Bozeman, MT (76 FR 70919). Interested parties were... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  3. "Hoffman v. Monsanto": Courts, Class Actions, and Perceptions of the Problem of GM Drift

    ERIC Educational Resources Information Center

    McLeod-Kilmurray, Heather

    2007-01-01

    "Hoffman v. Monsanto" raises questions about the civil litigation system. Are courts appropriate institutions, and are class actions the appropriate procedure, for resolving disputes about genetically modified organisms (GMOs)? After addressing the institutional question, this article focuses on procedure. Although class actions are designed to…

  4. 38 CFR 17.162 - Eligibility for Class II dental treatment without rating action.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... dental treatment without rating action. 17.162 Section 17.162 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.162 Eligibility for Class II dental treatment without rating action. When an application has been made for class II dental treatment under §...

  5. 38 CFR 17.162 - Eligibility for Class II dental treatment without rating action.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... dental treatment without rating action. 17.162 Section 17.162 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.162 Eligibility for Class II dental treatment without rating action. When an application has been made for class II dental treatment under §...

  6. 78 FR 49986 - Proposed Establishment of Class E Airspace; Loup City, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Loup City,...

  7. 77 FR 41939 - Proposed Establishment of Class E Airspace; Deer Lodge, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034....S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1... Proposed Establishment of Class E Airspace; Deer Lodge, MT AGENCY: Federal Aviation Administration...

  8. 78 FR 45478 - Proposed Establishment of Class E Airspace; Salmon, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Salmon,...

  9. 78 FR 41290 - Establishment of Class E Airspace; Elbow Lake, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... establish Class E airspace at Elbow Lake Municipal--Pride of the Prairie Airport, Elbow Lake, MN (78 FR... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR,...

  10. 78 FR 14032 - Proposed Establishment of Class E Airspace; Cherokee, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Cherokee,...

  11. 78 FR 48303 - Establishment of Class E Airspace; Tuba City, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... Tuba City VORTAC, Tuba City, AZ (78 FR 32086, May 29, 2013). In the regulatory text, the region..., 2013 (78 FR 32086), Airspace Docket No. 13-AWP-1, FR Doc. 2013-12623, is corrected as follows: Sec. 71... TRANSPORTATION Federal Aviation Administration 14 CFR Parts 71 Establishment of Class E Airspace; Tuba City,...

  12. 75 FR 64971 - Proposed Establishment of Class E Airspace; Central City, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-21

    ... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by reference in 14 CFR... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Central...

  13. 76 FR 72868 - Proposed Establishment of Class E Airspace; Boyne City, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Boyne City,...

  14. 76 FR 21268 - Proposed Establishment of Class E Airspace; Lincoln, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR... Proposed Establishment of Class E Airspace; Lincoln, OR AGENCY: Federal Aviation Administration (FAA),...

  15. 75 FR 5007 - Establishment of Class D and E Airspace; Panama City, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Establishment of Class D and E Airspace; Panama City,...

  16. 75 FR 16331 - Establishment of Class E Airspace; Panama City, Tyndall AFB, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Panama City, Tyndall...

  17. 75 FR 62460 - Revocation and Establishment of Class E Airspace; Northeast Alaska, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... establish other Class E airspace near the Eagle Airport, Eagle, AK (75 FR 30746). The proposal did not fully... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  18. 75 FR 62457 - Establishment of Class E Airspace; Port Clarence, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Federal Register to establish Class E airspace at Port Clarence, AK (75 FR 34393). Interested parties were... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  19. 75 FR 81110 - Establishment of Class E Airspace; Port Clarence, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ..., Tuesday, October 12, 2010 (75 FR 62457), FR Doc 2010-25479, page 62458, column 2 is corrected as follows... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Port Clarence, AK AGENCY... errors in the legal description and airport coordinates for Port Clarence Coast Guard Station...

  20. 75 FR 34393 - Proposed Establishment of Class E Airspace; Port Clarence, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Port...

  1. 78 FR 54413 - Proposed Establishment of Class E Airspace; Star, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Star, NC...

  2. 78 FR 18268 - Proposed Establishment of Class E Airspace; Blue Mesa, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Blue Mesa,...

  3. 77 FR 4713 - Proposed Establishment of Class E Airspace; Red Cloud, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Red Cloud,...

  4. 77 FR 75598 - Proposed Establishment of Class E Airspace; White Mountain, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; White...

  5. 78 FR 68699 - Establishment of Class E Airspace; Battle Mountain, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ... establishing Class E airspace at the Battle Mountain VORTAC navigation aid, Battle Mountain, NV (78 FR 58159... heading, as published in the Federal Register on September 23, 2013 (78 FR 58159), Airspace Docket No. 13- AWP-9, FR Doc. 2013-58159, is corrected as follows: On page 58160, column 1, line 2, remove...

  6. 75 FR 41983 - Establishment of Class D Airspace; San Marcos, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... Federal Register a notice of proposed rulemaking to establish Class D airspace for San Marcos Municipal Airport, San Marcos, TX (75 FR 22712) Docket No. FAA- 2010-0406. Interested parties were invited to... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation...

  7. 75 FR 14383 - Proposed Establishment of Class E Airspace; Lucin, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Lucin,...

  8. 77 FR 41108 - Proposed Establishment of Class E Airspace; Fort Garland, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-12

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Fort...

  9. 76 FR 53360 - Proposed Establishment of Class E Airspace; Stuart, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Stuart,...

  10. 76 FR 64236 - Establishment of Class E Airspace; New Market, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... establish Class E airspace at New Market, VA (76 FR 44288). Interested parties were invited to participate... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  11. 76 FR 44288 - Establishment of Class E Airspace; New Market, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; New Market, VA...

  12. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Adjustment in Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline...

  13. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Adjustment in Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline...

  14. 76 FR 3571 - Proposed Establishment of Class E Airspace; Kahului, HI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Kahului,...

  15. 75 FR 49868 - Proposed Establishment of Class E Airspace; Kalaupapa, HI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a regulatory evaluation... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Kalaupapa,...

  16. 42 CFR 416.185 - Process for establishing a new class of new technology IOLs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technology IOLs. 416.185 Section 416.185 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT... Payment Amounts for New Technology Intraocular Lenses Furnished by Ambulatory Service Centers § 416.185 Process for establishing a new class of new technology IOLs. (a) Announcement of deadline for requests...

  17. 77 FR 27148 - Proposed Establishment of Class E Airspace; Roundup, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-09

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and does not warrant... 71 continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace;...

  18. 77 FR 4711 - Proposed Establishment of Class E Airspace; Houston, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Houston,...

  19. 77 FR 4700 - Proposed Establishment of Class E Airspace; Freer, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Establishment of Class E Airspace; Freer,...

  20. 78 FR 68020 - Evaluation of Established Plant Pests for Action at Ports of Entry

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ... Animal and Plant Health Inspection Service Evaluation of Established Plant Pests for Action at Ports of Entry AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We are advising... the Administrator of the Animal and Plant Health Inspection Service (APHIS). Pursuant to the PPA,...

  1. 75 FR 17202 - Proposed Establishment of Long Beach, CA, Class C Airspace Area and Revision of Santa Ana (John...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... Revision of Santa Ana (John Wayne), CA, Class C Airspace Area; Public Meetings AGENCY: Federal Aviation... establish Class C airspace at Long Beach, CA, and revise the Santa Ana (John Wayne) Class C airspace area... Santa Ana (John Wayne), CA, Class C airspace area will be accepted. (b) The meetings will be open to...

  2. As the Pendulum Swings—Medical Products Class Actions Litigation in Canada: Recent Developments

    PubMed Central

    Pliszka, Peter J.; Armstrong, Sarah J.

    2013-01-01

    During the relatively short history of class proceedings in Canada, developers and manufacturers of medical devices and pharmaceuticals (“medical products”), including medical products designed for patients with diabetes, have found themselves at the receiving end of a significant number of class action claims. As a result, medical products litigation has become the battleground for some of the most significant developments in Canadian class actions law. This article provides a broad overview of some of the most significant developments. The authors pay particular attention to developments regarding the test for class action certification and consider whether high-profile dismissals of certification motions represent a trend toward raising the threshold for plaintiffs seeking to obtain certification of a proposed class action. The authors also consider a decision arising out of a lengthy class action common issues trial in which the medical device company was victorious. In the authors’ view, the class action pendulum in Canada, particularly as it relates to medical products claims, remains in motion. It behooves all affected players to keep their eye on this ball with rapt attention to see where it may move next. PMID:23566988

  3. As the pendulum swings--medical products class actions litigation in Canada: recent developments.

    PubMed

    Pliszka, Peter J; Armstrong, Sarah J

    2013-01-01

    During the relatively short history of class proceedings in Canada, developers and manufacturers of medical devices and pharmaceuticals ("medical products"), including medical products designed for patients with diabetes, have found themselves at the receiving end of a significant number of class action claims. As a result, medical products litigation has become the battleground for some of the most significant developments in Canadian class actions law. This article provides a broad overview of some of the most significant developments. The authors pay particular attention to developments regarding the test for class action certification and consider whether high-profile dismissals of certification motions represent a trend toward raising the threshold for plaintiffs seeking to obtain certification of a proposed class action. The authors also consider a decision arising out of a lengthy class action common issues trial in which the medical device company was victorious. In the authors' view, the class action pendulum in Canada, particularly as it relates to medical products claims, remains in motion. It behooves all affected players to keep their eye on this ball with rapt attention to see where it may move next. PMID:23566988

  4. 4 CFR 28.97 - Class actions in EEO cases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of GAO employees or applicants for employment, a complaint must first be filed with GAO in accordance with GAO Order 2713.2. (b) An appeal from GAO's disposition of any EEO class complaint may be submitted to the Board at the following times: (1) Within 20 days of receipt of a GAO determination...

  5. 23 CFR 771.115 - Classes of actions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... significantly affect the environment require an EIS (40 CFR 1508.27). The following are examples of actions that... on a new location. (3) New construction or extension of fixed rail transit facilities (e.g., rapid rail, light rail, commuter rail, automated guideway transit). (4) New construction or extension of...

  6. 23 CFR 771.115 - Classes of actions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... significantly affect the environment require an EIS (40 CFR 1508.27). The following are examples of actions that... on a new location. (3) Construction or extension of a fixed transit facility (e.g., rapid rail, light rail, commuter rail, bus rapid transit) that will not be located within an existing...

  7. 23 CFR 771.115 - Classes of actions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... significantly affect the environment require an EIS (40 CFR 1508.27). The following are examples of actions that... on a new location. (3) New construction or extension of fixed rail transit facilities (e.g., rapid rail, light rail, commuter rail, automated guideway transit). (4) New construction or extension of...

  8. 23 CFR 771.115 - Classes of actions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... significantly affect the environment require an EIS (40 CFR 1508.27). The following are examples of actions that... on a new location. (3) New construction or extension of fixed rail transit facilities (e.g., rapid rail, light rail, commuter rail, automated guideway transit). (4) New construction or extension of...

  9. 7 CFR 3407.5 - Classes of action.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... significant individual or cumulative effect on the quality of the human environment. These include those... regarding individual or cumulative effects on the quality of the human environment. Such actions generally... are projects which are determined to have a significant impact on the quality of the human...

  10. Co-Teaching an Online Action Research Class

    ERIC Educational Resources Information Center

    Wilson, Brent G.; Linder VanBerschot, Jennifer

    2014-01-01

    Two instructors report our experience co-teaching an action research (AR) required as part of an e-learning master's degree. Adopting a practice-centered stance we focus on the course activities of participants (instructors and students), with particular attention to the careful crafting of course elements with the goal of achieving an…

  11. NIH study uncovers new mechanism of action for class of chemotherapy drugs

    Cancer.gov

    NIH researchers have discovered a significant new mechanism of action for a class of chemotherapy drugs known as poly (ADP-ribose) polymerase inhibitors, or PARP inhibitors. They have also identified differences in the toxic capabilities of three drugs in

  12. Gender Consciousness and Class Action for Women: A Comparison of Black and White Female Adolescents.

    ERIC Educational Resources Information Center

    Hraba, Joseph; Yarbrough, Paul

    1983-01-01

    Examines the proposition that objective conditions of inequality, aspirations, media use, gender consciousness, class and race consciousness, and symbolic and social participation in the women's movement affect Black and White female adolescents' commitment to class action for women. Reports on research in three high schools in Waterloo, Iowa.…

  13. Phonemic Awareness Education with an ESL Class. Action Research Monograph.

    ERIC Educational Resources Information Center

    Barton, Anne Y.

    This study was designed to include a segment of phonemic awareness in a multi-level English-as-a-Second-Language (ESL) classroom as learning progress seemed to be inhibited in part by a lack of understanding of the structure of the English language. A survey was developed and administered to measure student progress to establish a baseline.…

  14. 21 CFR 109.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Establishment of tolerances, regulatory limits, and action levels. 109.4 Section 109.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD...

  15. 21 CFR 509.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Establishment of tolerances, regulatory limits, and action levels. 509.4 Section 509.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS UNAVOIDABLE...

  16. Grand Junction remedial action program. Analysis of currently approved and proposed procedures for establishing eligibility for remedial action. Final report

    SciTech Connect

    1980-12-01

    This analysis of the Grand Junction Remedial Action Program has been undertaken at the request of the Department of Energy (DOE) in response to proposals submitted by the Colorado Department of Health (CHD). In essence those proposals are for approval by DOE of alternative procedures for establishing the eligibility of structures for remedial action. Regardless of the preeminence accorded the RPISU method in the regulation, it is appropriate to question the assumption that this method gives better estimates of average long-term exposure than other potential methods of evaluation. The objectives here are to (1) review the reliability of the methods of measurement authorized by 10 CFR 12, i.e. the RPISU 6 sample method for determining RDC and the presumptive tests based on the indoor net average gamma exposure rate; (2) evaluate the reliability of the alternative measurement methods proposed by the CDH for determining eligibility for remedial action; and (3) recommend for DOE approval specific methods and applicable procedures that may be used to determine eligibility for remedial action with at least the same reliability as presently achieved with the RPISU 6 sample method.

  17. How to establish a first-class international scientific journal in China?

    PubMed

    Li, Zhen-Xi

    2006-11-21

    Hundreds of scientific journals are published in China. However, only scores of them are included in Science Citation Index by the Institute for Scientific Information, with impact factors of only 1 or less. Thus, how to establish a first-class international scientific journal in China is an important but difficult topic that deserves extensive exploration. World Journal of Gastroenterology (WJG) sets a good example although it has experienced setbacks on the road towards success. Concepts and pursuits that affirm the overall development direction, innovation and dreams that provide impetus and aspiration for higher objectives, team work and unique pattern that assure excellent quality and service, and culture and environment that also determine the speed and direction of the development, are believed to be the major factors contributing to the success of WJG. It is recommended that the effective resolution to the above issue is to learn from Chinese examples such as WJG rather than from "how foreign journals do". PMID:17109509

  18. Perceptual classes established with forced-choice primary generalization tests and transfer of function.

    PubMed Central

    Reeve, K F; Fields, L

    2001-01-01

    In Experiment 1, 20 college students learned two identity conditional discriminations using squares that differed in interior-fill percentage (called Fill23 and Fill77). A two-choice generalization test was then presented with number of test trials varied across groups of subjects. The test samples were 19 squares that ranged in fill value from 23% to 77%; the comparisons were squares with Fill23 and Fill77. The resulting gradients did not vary as a function of number of test trials. When the generalization test was repeated with a third comparison, "neither," the ranges of fill values that occasioned the exclusive selection of Fill23 or Fill77 were direct functions of the number of prior two-choice generalization trials. Finally, a disriminability test revealed that Fill23 and Fill77 were disciminable from the intermediate fill values. In Experiment 2, perceptual classes were established with 5 new students using 760 forced-choice generalization test trials. The student were then trained to select a different glyph in the presence of Fill23 and Fill77, followed by a three-choice generalization test in which the 19 fill stimuli served as samples and the two glyphs served as comparisons. The gradients ovelapped with those previously obtained during the three-choice generalization test that used Fill23 and Fill77 as comparisons. Finally, a discriminability test showed that many adjacent stimuli along thc fill dimension were discriminable from each other. Together, the results of both experiments suggest that ranges of fill-based stimuli functioned as members of perceptual classes, and each class also functioned as a transfer network for a new selection-based response. PMID:11516117

  19. Establishing the customized occlusal plane in systemized surgical treatment objectives of class III.

    PubMed

    Baek, Seung-Hak; Ahn, Hyo-Won; Yang, Sang-Duck; Choi, Jin-Young

    2011-09-01

    The purpose of this study was to present a new approach for establishing the customized occlusal plane for an individual patient in systemized surgical treatment objective of class III cases. After the correction of incisor inclination to occlusal planes (U1-MxOP and L1-MnOP), the intermaxillary relationship can be established with normal overbite/overjet and maximum intercuspation. The anterior limits of the maxilla and the mandible can be positioned according to A to N perpendicular, Frankfort horizontal (FH) to AB plane angle, and upper incisor display. The vertical level of the upper first molar can then be determined in relation to the Y plane (an imaginary arch drawn using the distance between the lower incisor edge point and the rotation center point of the condylar head as a radius) and a triangle projected by the upper and lower limits of the FH to the occlusal plane (FH-OP triangle). Soft-tissue facial balance can be checked with the lip/chin projection in relation to the true vertical line at subnasale and the lower third facial height ratio. Appropriate superior impaction of the posterior part of the maxilla in relation to the Y plane and FH-OP triangle in case 1 produced significant improvement of the facial profile and occlusion. However, case 2 showed that the amount of superior impaction of the posterior part of the maxilla was not enough to produce a significant setback of the mandible and retraction of the lip and chin. The systemized surgical treatment objective flowchart that could set the customized occlusal plane for an individual patient might provide a useful guideline for obtaining optimal aesthetics and functional occlusion in class III cases. PMID:21959417

  20. Industrial Sites Project Establishment of Final Action Levels, Rev. No.: 0

    SciTech Connect

    Boehlecke, Robert F.

    2006-02-01

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) oversees numerous sites on the Nevada Test Site (NTS) and other locations in the State of Nevada that have been impacted by activities related to the development and testing of nuclear devices and by other activities. NNSA/NSO is responsible for protecting members of the public, including site workers, from harmful exposure to both chemical and radiological contaminants at these sites as they remediate these sites. The Nevada Division of Environmental Protection (NDEP) is the primary state agency responsible for protection of human health and the environment with respect to chemical and radiological wastes. In 1996 the DOE, U.S. Department of Defense, and the State of Nevada entered into an agreement known as the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996). Appendix VI to the FFACO describes the strategy employed to plan, implement, and complete environmental corrective action activities at NTS and other locations in the state of Nevada. One of the categories of corrective action units (CAUs) is Industrial Sites, which consists of approximately 1,150 locations that may require some level of investigation and corrective action. To evaluate the need for the extent of corrective action at a particular site, NNSA/NSO assesses the potential impacts to receptors by comparing measurements of contaminant concentrations to risk-based (chemical) and dose-based (radionuclide) standards (action levels). Preliminary action levels (PALs) are established as part of the data quality objective (DQO) process, and are presented in one or more FFACO documents generated as part of the corrective action process. This document formally defines and clarifies the NDEP-approved process NNSA/NSO Industrial Sites Project uses to fulfill the requirements of the FFACO and state regulations. This process establishes final action levels (FALs) based on the risk

  1. 39 CFR 3.10. - Establishment of rates and classes of competitive products not of general applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... proceedings of the Governors, and any supporting documentation required by 39 CFR Part 3015, to be filed with... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment of rates and classes of competitive... rates and classes of competitive products not of general applicability. This section relates to...

  2. 39 CFR 3.10. - Establishment of rates and classes of competitive products not of general applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... proceedings of the Governors, and any supporting documentation required by 39 CFR Part 3015, to be filed with... 39 Postal Service 1 2014-07-01 2014-07-01 false Establishment of rates and classes of competitive... rates and classes of competitive products not of general applicability. This section relates to...

  3. 39 CFR 3.10. - Establishment of rates and classes of competitive products not of general applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... proceedings of the Governors, and any supporting documentation required by 39 CFR Part 3015, to be filed with... 39 Postal Service 1 2011-07-01 2011-07-01 false Establishment of rates and classes of competitive... rates and classes of competitive products not of general applicability. This section relates to...

  4. 39 CFR 3.10. - Establishment of rates and classes of competitive products not of general applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... proceedings of the Governors, and any supporting documentation required by 39 CFR Part 3015, to be filed with... 39 Postal Service 1 2012-07-01 2012-07-01 false Establishment of rates and classes of competitive... rates and classes of competitive products not of general applicability. This section relates to...

  5. 39 CFR 3.10. - Establishment of rates and classes of competitive products not of general applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... proceedings of the Governors, and any supporting documentation required by 39 CFR Part 3015, to be filed with... 39 Postal Service 1 2013-07-01 2013-07-01 false Establishment of rates and classes of competitive... rates and classes of competitive products not of general applicability. This section relates to...

  6. Class Action.

    ERIC Educational Resources Information Center

    Schorr, Jonathan

    1993-01-01

    Teach for America, the recent private reincarnation of the 1960s Teacher Corps, sends college graduates to teach for two years in understaffed schools. One TFA participant warns those planning President Clinton's national service program that eight weeks of training is insufficient to train competent teachers. Unless teachers are smartly selected,…

  7. Taking a closer look at the managed care class actions: impact litigation as an assist to the market.

    PubMed

    Cerminara, Kathy L

    2002-01-01

    Professor Cerminara examines the use of class action lawsuits to empower individuals to challenge health care decision-making. The article begins by noting the benefits of class actions which provide strength in numbers and a far-ranging impact by challenging policy decisions and encouraging corporate responsiveness. Professor Cerminara concludes that class actions are but one step in the process of empowering individuals and decreasing their resentment of the lack of process currently within the health care system. PMID:12430380

  8. For the Welfare of Children: Lessons Learned from Class Action Litigation

    ERIC Educational Resources Information Center

    Meltzer, Judith, Ed.; Joseph, Rachel Molly, Ed.; Shookhoff, Andy, Ed.

    2012-01-01

    This series of papers brings together distinguished experts writing on the use of class action litigation to reform public child welfare systems. It is an effort to tease out of four decades of experience in this work, the factors that increase the likelihood that litigation will result in successful system reform. This publication is an outgrowth…

  9. Dealing with Differences: Taking Action on Class, Race, Gender, and Disability.

    ERIC Educational Resources Information Center

    Ellis, Angele; Llewellyn, Marilyn

    This study/action guide was developed from a project on difference and prejudice that was implemented in a Pittsburgh (Pennsylvania) high school in 1994 and evaluated through surveys and in-depth interviews. The book provides a basic introduction to difference and prejudice organized about issues of class, race, gender, and disability in the…

  10. The Use of Psychodrama Action Techniques in a Race Relations Class

    ERIC Educational Resources Information Center

    Kranz, Peter L.; Ramirez, Sylvia Z.; Lund, Nick L.

    2007-01-01

    This article describes psychodrama action techniques that were effectively implemented in a university-level race relations course. Essential elements of these techniques included acting out and critical self-examination of the individual's personal beliefs. In a semi-structured class format in which uncensored spontaneity was stressed, students…

  11. 10 CFR Appendix D to Subpart D of... - Classes of Actions That Normally Require EISs

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... hazardous waste as designated in 40 CFR part 261). D12Siting, construction, and operation of incinerators... designated in 40 CFR part 261.4(b)). ... 10 Energy 4 2011-01-01 2011-01-01 false Classes of Actions That Normally Require EISs D Appendix...

  12. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... designated in 40 CFR part 261). D12 Incinerators Siting, construction, and operation of incinerators, other... in 40 CFR 261.4(b)). ... 10 Energy 4 2014-01-01 2014-01-01 false Classes of Actions that Normally Require EISs D Appendix...

  13. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... designated in 40 CFR part 261). D12Incinerators Siting, construction, and operation of incinerators, other... in 40 CFR 261.4(b)). ... 10 Energy 4 2012-01-01 2012-01-01 false Classes of Actions that Normally Require EISs D Appendix...

  14. 10 CFR Appendix D to Subpart D of... - Classes of Actions That Normally Require EISs

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... hazardous waste as designated in 40 CFR part 261). D12Siting, construction, and operation of incinerators... designated in 40 CFR part 261.4(b)). ... 10 Energy 4 2010-01-01 2010-01-01 false Classes of Actions That Normally Require EISs D Appendix...

  15. 10 CFR Appendix D to Subpart D of... - Classes of Actions that Normally Require EISs

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... designated in 40 CFR part 261). D12Incinerators Siting, construction, and operation of incinerators, other... in 40 CFR 261.4(b)). ... 10 Energy 4 2013-01-01 2013-01-01 false Classes of Actions that Normally Require EISs D Appendix...

  16. 18 CFR 707.8 - Typical classes of action requiring similar treatment under NEPA.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Typical classes of action requiring similar treatment under NEPA. 707.8 Section 707.8 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA)...

  17. 18 CFR 707.8 - Typical classes of action requiring similar treatment under NEPA.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Typical classes of action requiring similar treatment under NEPA. 707.8 Section 707.8 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA)...

  18. 18 CFR 707.8 - Typical classes of action requiring similar treatment under NEPA.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Typical classes of action requiring similar treatment under NEPA. 707.8 Section 707.8 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA)...

  19. CSMMI: class-specific maximization of mutual information for action and gesture recognition.

    PubMed

    Wan, Jun; Athitsos, Vassilis; Jangyodsuk, Pat; Escalante, Hugo Jair; Ruan, Qiuqi; Guyon, Isabelle

    2014-07-01

    In this paper, we propose a novel approach called class-specific maximization of mutual information (CSMMI) using a submodular method, which aims at learning a compact and discriminative dictionary for each class. Unlike traditional dictionary-based algorithms, which typically learn a shared dictionary for all of the classes, we unify the intraclass and interclass mutual information (MI) into an single objective function to optimize class-specific dictionary. The objective function has two aims: 1) maximizing the MI between dictionary items within a specific class (intrinsic structure) and 2) minimizing the MI between the dictionary items in a given class and those of the other classes (extrinsic structure). We significantly reduce the computational complexity of CSMMI by introducing an novel submodular method, which is one of the important contributions of this paper. This paper also contributes a state-of-the-art end-to-end system for action and gesture recognition incorporating CSMMI, with feature extraction, learning initial dictionary per each class by sparse coding, CSMMI via submodularity, and classification based on reconstruction errors. We performed extensive experiments on synthetic data and eight benchmark data sets. Our experimental results show that CSMMI outperforms shared dictionary methods and that our end-to-end system is competitive with other state-of-the-art approaches. PMID:24983106

  20. Voluntary climate change mitigation actions of young adults: a classification of mitigators through latent class analysis.

    PubMed

    Korkala, Essi A E; Hugg, Timo T; Jaakkola, Jouni J K

    2014-01-01

    Encouraging individuals to take action is important for the overall success of climate change mitigation. Campaigns promoting climate change mitigation could address particular groups of the population on the basis of what kind of mitigation actions the group is already taking. To increase the knowledge of such groups performing similar mitigation actions we conducted a population-based cross-sectional study in Finland. The study population comprised 1623 young adults who returned a self-administered questionnaire (response rate 64%). Our aims were to identify groups of people engaged in similar climate change mitigation actions and to study the gender differences in the grouping. We also determined if socio-demographic characteristics can predict group membership. We performed latent class analysis using 14 mitigation actions as manifest variables. Three classes were identified among men: the Inactive (26%), the Semi-active (63%) and the Active (11%) and two classes among women: the Semi-active (72%) and the Active (28%). The Active among both genders were likely to have mitigated climate change through several actions, such as recycling, using environmentally friendly products, preferring public transport, and conserving energy. The Semi-Active had most probably recycled and preferred public transport because of climate change. The Inactive, a class identified among men only, had very probably done nothing to mitigate climate change. Among males, being single or divorced predicted little involvement in climate change mitigation. Among females, those without tertiary degree and those with annual income €≥16801 were less involved in climate change mitigation. Our results illustrate to what extent young adults are engaged in climate change mitigation, which factors predict little involvement in mitigation and give insight to which segments of the public could be the audiences of targeted mitigation campaigns. PMID:25054549

  1. 77 FR 39653 - Proposed Establishment of Class E Airspace; Reidsville, GA, and Proposed Amendment of Class E...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Airspace at Reidsville, GA. Separation of existing Class E airspace surrounding Swinton Smith Field...

  2. 75 FR 47736 - Amendment of Class D and E Airspace, Establishment of Class E Airspace; Patuxent River, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... Airpark, excluding that airspace within Restricted Areas R-4005 and R-4007 when active. This Class...

  3. 75 FR 4268 - Establishment of Class D and E Airspace and Modification of Class E Airspace; State College, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... modifying Class E airspace at University Park Airport, State College, PA (74 FR 54763). A newly commissioned... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  4. 78 FR 48290 - Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... notice of proposed rulemaking (NPRM) to amend Class D airspace for Waco, TX (78 FR 33015) Docket No. FAA...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  5. How to establish a first-class international scientific journal in China?

    PubMed Central

    Li, Zhen-Xi

    2006-01-01

    Hundreds of scientific journals are published in China. However, only scores of them are included in Science Citation Index by the Institute for Scientific Information, with impact factors of only 1 or less. Thus, how to establish a first-class international scientific journal in China is an important but difficult topic that deserves extensive exploration. World Journal of Gastroenterology (WJG) sets a good example although it has experienced setbacks on the road towards success. Concepts and pursuits that affirm the overall development direction, innovation and dreams that provide impetus and aspiration for higher objectives, team work and unique pattern that assure excellent quality and service, and culture and environment that also determine the speed and direction of the development, are believed to be the major factors contributing to the success of WJG. It is recommended that the effective resolution to the above issue is to learn from Chinese examples such as WJG rather than from “how foreign journals do”. PMID:17109509

  6. 78 FR 21084 - Proposed Amendment of Class D and E Airspace, and Establishment of Class E Airspace; Oceana NAS, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... Traffic Control Tower at Oceana NAS (Apollo Soucek Field) operating on a part time basis. This action...-0038; Airspace Docket No. 13-AEA-2, at the beginning of your comments. You may also submit and...

  7. 10 CFR 1021.410 - Application of categorical exclusions (classes of actions that normally do not require EAs or EISs).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Application of categorical exclusions (classes of actions that normally do not require EAs or EISs). 1021.410 Section 1021.410 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Typical Classes of Actions § 1021.410 Application of...

  8. Establishing auditory stimulus control over an eight-member equivalence class via conditional discrimination procedures.

    PubMed Central

    Saunders, R R; Wachter, J; Spradlin, J E

    1988-01-01

    Two eight-member equivalence classes of visual stimuli were established during three phases of a training program. In Phase 1, two training arrangements were compared. In one, 3 subjects were taught on different trials to select from a single pair of comparison stimuli (A1, A2) in response to eight sample stimuli that were trained in pairs (B1, B2; C1, C2; D1, D2; E1, E2). In the second arrangement, subjects were taught to select from four pairs of comparisons (B1, B2; C1, C2; D3, D2; E2, E2) in response to two samples (A1, A2). Training with the single pair of comparison stimuli resulted in the development of equivalence relations (B1C1, B2C2, D1B1, D2B2, B1E1, B2E2, C1D1, C2D2, C1E1, C2E2, D1E1, D2E2, and their reciprocals) between the sample stimuli without direct training of these relations. In the other training arrangement, these relations among the comparison stimuli developed in the performance of 1 subject only. In Phase 2, three new pairs of stimuli (F1, F2; G1, G2; H1, H2) were substituted for three of the original pairs (B1, B2; C1, C2; D1, D2) and the training arrangements for the groups were reversed. Following training, the performances that showed equivalence relations on the probes in the first phase also showed equivalence relations in the second phase. If such relations did not develop in the first phase, they did not do so in the second phase. In Phase 3, relations between stimuli across the two previous phases (e.g., B1F1, B2F2, B1G1, B2H2, C1F1, etc.) were investigated. The 4 subjects whose performances showed the development of these relations were taught to select one stimulus from each class (E1 and E2) in response to a verbal label (I1 and I2) and then were tested to see if the verbal label controlled responding to the remaining members of the class (e.g., I1A1, I2A2, I1B1, I2B2, etc.). For 3 subjects, this generalized control occurred; for the 4th, generalization occurred only after verbal training with a second pair of visual stimuli (F1

  9. Defending the next round of non-profit hospital class action lawsuits.

    PubMed

    Olson, Mark D

    2005-01-01

    Recent controversies surrounding how not-for-profit hospitals price to and collect from the uninsured have resulted in class action lawsuits, investigations by state attorneys general, and other governmental investigations. The author argues that oversight at the hospital governing board level has been lax and sets forth a series of specific steps that hospital boards should take to deal with these controversies whether or not their specific hospital or hospital system has been investigated or sued. PMID:18973003

  10. The TACO approach to establishing risk-based corrective action objectives for a former industrial facility

    SciTech Connect

    Pope, J.L.; Nienkerk, M.M.

    1999-07-01

    Illinois' Tiered Approach to Corrective Action Objectives (35 Ill Adm Code Part 742) regulations have been used to evaluate site-specific remediation objectives for a site contaminated with methylene chloride. Remediation objectives evaluated through this approach have provided the opportunity to implement a technically feasible cleanup of the site. Site-specific soil cleanup objectives of 24 milligrams per kilogram (mg/kg) for the unsaturated soils and 2,000 mg/kg for the underlying saturated soils were established. These cleanup objectives were based on the use of a city ordinance prohibiting well installation and groundwater use within one-half mile of the site and did not require the use of an engineered barrier which would have to be maintained throughout the life of the facility. Without the city ordinance and risk-based cleanup objectives, the cleanup objective would have been 0.02 mg/kg, making remediation of the site technically and economically infeasible.

  11. Does Homework Matter? A Comparison of Homework with Established Predictors of Exam Performance in Large College Classes

    ERIC Educational Resources Information Center

    Galyon, Charles E.; Blondin, Carolyn A.; Forbes, Bethany E.; Williams, Robert L.

    2013-01-01

    The authors developed a methodology for evaluating student answers on homework assigned in 3 sections (total N = 167) of an undergraduate educational psychology course. The potential of homework to predict exam scores was compared with that of two established predictors (critical thinking and participation in class discussion). The findings…

  12. Establishing a Telementoring Program that Can Be Used in Vocational Classes.

    ERIC Educational Resources Information Center

    Wheeldon, Robert Sean; Lehmann, Jean P.

    1999-01-01

    Describes an existing telementoring project formed between a large computer-based company and a transition class in a small rural high school and provides information about the steps necessary to implement such a program. (Author)

  13. 36 CFR Exhibit B to Part 906 - Guidelines for Establishing Strategy To Implement Affirmative Action Personnel Plan

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Strategy To Implement Affirmative Action Personnel Plan B Exhibit B to Part 906 Parks, Forests, and Public.... B Exhibit B to Part 906—Guidelines for Establishing Strategy To Implement Affirmative Action... office of the State Employment Service (or union hiring hall when union labor is required). (6)...

  14. 36 CFR Exhibit B to Part 906 - Guidelines for Establishing Strategy To Implement Affirmative Action Personnel Plan

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Strategy To Implement Affirmative Action Personnel Plan B Exhibit B to Part 906 Parks, Forests, and Public.... B Exhibit B to Part 906—Guidelines for Establishing Strategy To Implement Affirmative Action... office of the State Employment Service (or union hiring hall when union labor is required). (6)...

  15. 36 CFR Exhibit B to Part 906 - Guidelines for Establishing Strategy To Implement Affirmative Action Personnel Plan

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Strategy To Implement Affirmative Action Personnel Plan B Exhibit B to Part 906 Parks, Forests, and Public.... B Exhibit B to Part 906—Guidelines for Establishing Strategy To Implement Affirmative Action... office of the State Employment Service (or union hiring hall when union labor is required). (6)...

  16. 36 CFR Exhibit B to Part 906 - Guidelines for Establishing Strategy To Implement Affirmative Action Personnel Plan

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Strategy To Implement Affirmative Action Personnel Plan B Exhibit B to Part 906 Parks, Forests, and Public.... B Exhibit B to Part 906—Guidelines for Establishing Strategy To Implement Affirmative Action... office of the State Employment Service (or union hiring hall when union labor is required). (6)...

  17. 36 CFR Exhibit B to Part 906 - Guidelines for Establishing Strategy To Implement Affirmative Action Personnel Plan

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Strategy To Implement Affirmative Action Personnel Plan B Exhibit B to Part 906 Parks, Forests, and Public.... B Exhibit B to Part 906—Guidelines for Establishing Strategy To Implement Affirmative Action... office of the State Employment Service (or union hiring hall when union labor is required). (6)...

  18. The role of mycorrhization helper bacteria in the establishment and action of ectomycorrhizae associations

    PubMed Central

    Rigamonte, Tatiana Alves; Pylro, Victor Satler; Duarte, Gabriela Frois

    2010-01-01

    More than 95 % short roots of most terrestrial plants are colonized by mycorrhizal fungi as soon as they emerge in the upper soil profiles. The establishment of mycorrhizal association involves profound morphological and physiological changes in root and fungus. It is affected by other rhizospheric microorganisms, specifically by the bacteria. Bacteria may have developed mechanisms of selective interaction with surrounding microorganisms, with neutral or positive effects on mycorrhizal associations, but negative effect on root pathogens in general. Because of the beneficial effect of bacteria on mycorrhizae, the concept of Mycorrhization Helper Bacteria (MHB) was created. Five main actions of MHB on mycorrhizae were proposed: in the receptivity of root to the mycobiont, in root-fungus recognition, in fungal growth, in the modification of rhizospheric soil and in the germination of fungal propagules. MHB appear to develop a gradation of specificity for the mycobiont, but little or no specificity for the host plant in symbiosis. One of the main groups of MHB is the fluorescent Pseudomonas, well represented in diversity and cell density studies of mycorrhizal associations. This review covers the activity of MHB in the establishment of ectomycorrhizae, taking as model the effects of Pseudomonas sp. described in scientific literature. PMID:24031563

  19. Dynamics of the Establishment of Systemic Potyvirus Infection: Independent yet Cumulative Action of Primary Infection Sites

    PubMed Central

    Lafforgue, Guillaume; Tromas, Nicolas; Elena, Santiago F.

    2012-01-01

    In the clinic, farm, or field, for many viruses there is a high prevalence of mixed-genotype infections, indicating that multiple virions have initiated infection and that there can be multiple sites of primary infection within the same host. The dynamic process by which multiple primary infection sites interact with each other and the host is poorly understood, undoubtedly due to its high complexity. In this study, we attempted to unravel the basic interactions underlying this process using a plant RNA virus, as removing the inoculated leaf can instantly and rigorously eliminate all primary infection sites. Effective population size in the inoculated leaf and time of removal of the inoculated leaf were varied in experiments, and it was found that both factors positively influenced if the plant became systemically infected and what proportion of cells in the systemic tissue were infected, as measured by flow cytometry. Fitting of probabilistic models of infection to our data demonstrated that a null model in which the action of each focus is independent of the presence of other foci was better supported than a dependent-action model. The cumulative effect of independently acting foci therefore determined when plants became infected and how many individual cells were infected. There was no evidence for interference between primary infection sites, which is surprising given the planar structure of leaves. By showing that a simple null model is supported, we experimentally confirmed—to our knowledge for the first time—the minimal components that dictate interactions of a conspecific virus population establishing systemic infection. PMID:22993154

  20. 77 FR 12760 - Proposed Establishment of Class E Airspace; Wilkes-Barre, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ..., the proposed rule published July 1, 2011 (76 FR 38585), is withdrawn. FOR FURTHER INFORMATION CONTACT... Airport, Wilkes-Barre, PA (76 FR 38585). Subsequent to publication the FAA found that Class E airspace..., 1, 2011 (76 FR 38585) (FR Doc. 2011-16664), is hereby withdrawn. Authority: 49 U.S.C. 106(g);...

  1. Exploring Possible Selves in a First-Year Physics Foundation Class: Engaging Students by Establishing Relevance

    ERIC Educational Resources Information Center

    Bennett, Dawn; Roberts, Lynne; Creagh, Christine

    2016-01-01

    Students often complain that they cannot see the relevance of what they are being taught in foundation physics classes. While revising and adjusting the curriculum and teaching are important, this study suggests it might also be useful to help students view their learning in relation to their future career aspirations. This paper reports on a…

  2. The First Day of Class: Establishing Rapport as Well as Ground Rules.

    ERIC Educational Resources Information Center

    Hudson, Larry

    This document summarizes a presentation and student responses from a workshop for graduate teaching assistants (GTAs) attended by 84 GTAs. The focus of the presentation and discussions was on the first day of class, setting goals for the course and introducing the subjects and the instructor. Participants entered their comments into an Alpha Smart…

  3. Establishing Response and Stimulus Classes for Initiating Joint Attention in Children with Autism

    ERIC Educational Resources Information Center

    Jones, Emily A.

    2009-01-01

    The absence of the fundamental skill of "initiating joint attention" reflects the social-communicative impairment characterizing autism. Initiating joint attention is related to social and communication development as well as intervention outcomes for children with autism. A behaviorally based intervention was used to teach an expanded class of…

  4. 76 FR 75448 - Establishment of Class D and E Airspace; Frederick, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... Class D and E airspace at Frederick, MD, to accommodate new Area Navigation (RNAV) Global Positioning... and E airspace for the new Frederick Municipal Airport, Frederick, MD (76 FR 50156) Docket No. FAA... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  5. 75 FR 41774 - Proposed Establishment and Modification of Class E Airspace; Deer Park, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3...; Deer Park, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  6. 78 FR 78299 - Proposed Establishment of Class E Airspace; Truth or Consequences, NM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... action must submit with those comments a self-addressed stamped postcard on which the following statement... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  7. 75 FR 73016 - Proposed Establishment of Class E Airspace; Kenbridge, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... the Internet at http: www.regulations.gov. FOR FURTHER INFORMATION CONTACT: Richard Horrocks...: www.regulations.gov. Comments wishing the FAA to acknowledge receipt of their comments on this action... http: www.regulations.gov. Recently published rulemaking documents can also be accessed through the...

  8. 78 FR 52111 - Proposed Establishment of Class E Airspace; Aliceville, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... George Downer Airport. This action would enhance the safety and airspace management of Instrument...

  9. 78 FR 25005 - Proposed Establishment of Class E Airspace; Port Townsend, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Airspace; Port Townsend, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of...

  10. 77 FR 71367 - Proposed Establishment of Class E Airspace; Round Mountain, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Mountain, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  11. 77 FR 3185 - Proposed Establishment of Class E Airspace; Grasonville, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 [Amended] 2. The incorporation...-3187] [FR Doc No: 2012-1203] DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part... Procedure (SIAP) serving Queen Anne E.R. Heliport. This action would [[Page 3186

  12. 75 FR 68558 - Proposed Establishment of Class E Airspace; New Hampton, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Instrument Approach Procedures (SIAP) for the Mercy Medical Center Heliport. The FAA is taking this action...

  13. 76 FR 39038 - Proposed Establishment of Class E Airspace; Lebanon, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation by reference in 14 CFR... Instrument Approach Procedures at Keller Brothers Airport. This action would enhance the safety and...

  14. 78 FR 41337 - Proposed Establishment of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Centers (ARTCCs). The FAA is proposing this action to enhance the safety and management of...

  15. 78 FR 41336 - Proposed Establishment of Class E Airspace; Wasatch, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR 71.1... FAA is proposing this action to enhance the safety and management of aircraft operations within...

  16. Novae. Fermi establishes classical novae as a distinct class of gamma-ray sources.

    PubMed

    2014-08-01

    A classical nova results from runaway thermonuclear explosions on the surface of a white dwarf that accretes matter from a low-mass main-sequence stellar companion. In 2012 and 2013, three novae were detected in γ rays and stood in contrast to the first γ-ray-detected nova V407 Cygni 2010, which belongs to a rare class of symbiotic binary systems. Despite likely differences in the compositions and masses of their white dwarf progenitors, the three classical novae are similarly characterized as soft-spectrum transient γ-ray sources detected over 2- to 3-week durations. The γ-ray detections point to unexpected high-energy particle acceleration processes linked to the mass ejection from thermonuclear explosions in an unanticipated class of Galactic γ-ray sources. PMID:25082700

  17. Fermi Establishes Classical Novae as a Distinct Class of Gamma-ray Sources

    NASA Technical Reports Server (NTRS)

    Ackermann, M.; Ajello, M.; Albert, A.; Baldini, L.; Ballet, J.; Bastieri, D.; Bellazzini, R.; Bissaldi, E.; Blandford, R. D.; Bloom, E. D.; Bottacini, E.; Brandt, T. J.; Bregeon, J.; Bruel, P.; Buehler, R.; Buson, S.; Caliandro, G. A.; Cameron, R. A.; Caragiulo, M.; Caraveo, P. A.; Ferrara, E. C.; Harding, A. K.; Hays, E.; Perkins, J. S.; Thompson, D. J.

    2014-01-01

    A classical nova results from runaway thermonuclear explosions on the surface of a white dwarf that accretes matter from a low-mass main-sequence stellar companion. In 2012 and 2013, three novae were detected in gamma rays and stood in contrast to the first gamma-ray detected nova V407 Cygni 2010, which belongs to a rare class of symbiotic binary systems. Despite likely differences in the compositions and masses of their white dwarf progenitors, the three classical novae are similarly characterized as soft spectrum transient gamma-ray sources detected over 2-3 week durations. The gamma-ray detections point to unexpected high-energy particle acceleration processes linked to the mass ejection from thermonuclear explosions in an unanticipated class of Galactic gamma-ray sources.

  18. 77 FR 71131 - Implementation of the Middle Class Tax Relief and Job Creation Act of 2012; Establishment of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-29

    ...In this document, the Commission adopts rules to create a Do- Not-Call registry for public safety answering points (PSAPs) as required by the ``Middle Class Tax Relief and Job Creation Act of 2012'' (Tax Relief Act). Specifically, section 6507 of the Tax Relief Act requires the Commission, among other things, to establish a registry that allows PSAPs to register telephone numbers on a Do-Not-......

  19. 77 FR 37362 - Implementation of the Middle Class Tax Relief and Job Creation Act of 2012; Establishment of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ...In this document, the Commission initiates a proceeding to create a Do-Not-Call registry for public safety answering points (PSAPs) as required by the ``Middle Class Tax Relief and Job Creation Act of 2012'' (Tax Relief Act). Specifically, section 6507 of the Tax Relief Act requires the Commission, among other things, to establish a registry that allows PSAPs to register telephone numbers on a......

  20. Exploring perception-action relations in music production: The asymmetric effect of tonal class.

    PubMed

    Jebb, Andrew T; Pfordresher, Peter Q

    2016-05-01

    When playing musical passages, performers integrate the pitch content of auditory feedback with current action plans. However, this process depends on the degree to which the musical structure of the feedback melody is perceived as similar to the structure of what is planned. Four experiments reported here explored the relationship between the tonal class of planned melodies (tonal or atonal) and the sequence of events formed by auditory feedback. Participants produced short melodies from memory that were either tonal (Experiments 1 and 3) or atonal (Experiments 2 and 4). Auditory feedback matched the planned melody with respect to contour but could vary in tonal class. The results showed that when participants planned a tonal melody, atonal feedback was treated as unrelated to the planned sequence. However, when planning an atonal melody, tonal feedback was still treated as similar to the planned sequence. This asymmetric similarity mirrors findings found within the music perception literature and implies that schematic musical knowledge is highly active in determining perception-action relations during music performance. PMID:26594878

  1. 78 FR 76055 - Establishment of Class E Airspace; Donlin Creek, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-16

    ... rulemaking (NPRM) to establish controlled airspace at Donlin Creek, AK (78 FR 58490). Interested parties were...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  2. 76 FR 40797 - Establishment of Class E Airspace; Lincoln City, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ... rulemaking to establish controlled airspace at Lincoln City, OR (76 FR 21268). Interested parties were... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  3. 78 FR 65556 - Establishment of Class E Airspace; Cut Bank, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... proposed rulemaking (NPRM) to establish controlled airspace at Cut Bank, MT (78 FR 45474). Interested... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR,...

  4. 78 FR 38197 - Establishment of Class E Airspace; Port Townsend, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... establish controlled airspace at Port Townsend, WA (78 FR 25005). Interested parties were invited to... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  5. 78 FR 34554 - Establishment of Class E Airspace; Blue Mesa, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ...) to establish controlled airspace at Blue Mesa, CO (78 FR 18268). Interested parties were invited to... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  6. 77 FR 48060 - Establishment of Class E Airspace; Fort Morgan, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... notice of proposed rulemaking (NPRM) to establish controlled airspace at Fort Morgan, CO (77 FR 33687... a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  7. 77 FR 49720 - Establishment of Class E Airspace; Chenega Bay, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... proposed rulemaking (NPRM) to establish controlled airspace at Chenega Bay, AK (77 FR 31548). Interested... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  8. 75 FR 63066 - Establishment of Class E Airspace; Clifton/Morenci, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... establish controlled airspace at Clifton/Morenci, AZ (75 FR 44725). Interested parties were invited to... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  9. 78 FR 40381 - Establishment of Class E Airspace; Grand Canyon, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ...) to establish controlled airspace at Grand Canyon, AZ (78 FR 25404). Interested parties were invited... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  10. 75 FR 226 - Establishment of Class E Airspace; Riverside/Rubidoux Flabob Airport, Riverside, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ... establish controlled airspace at Riverside/Rubidoux Flabob Airport, Riverside, CA (74 FR 52704). Interested... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  11. A Multi-Institution Study on the Effectiveness of ClassAction to Promote Student Understanding in Astro 101

    NASA Astrophysics Data System (ADS)

    Lee, Kevin M.; French, R. S.; Hands, D. R.; Loranz, D. R.; Martino, D.; Rudolph, A. L.; Wysong, J.; Young, T. S.; Prather, E. E.; CATS

    2010-01-01

    ClassAction is a computer database of materials designed to enhance the conceptual understanding and reasoning abilities of Astro 101 students by promoting interactive engagement and providing rapid feedback. The main focus is dynamic conceptual questions largely based upon graphics that can be projected in the classroom. Instructors have the capability to select, order, and recast these questions into alternate permutations based on their own preferences and student responses. Instructors may also provide feedback through extensive resources including outlines, graphics, and simulations. The Light and Spectroscopy Concept Inventory (LSCI) is a multiple-choice assessment instrument which focuses on the electromagnetic spectrum, Doppler shift, Wien's Law, Stefan-Boltzmann Law, and Kirchhoff's Laws. Illustrative examples of how these concepts are targeted by the questions and resources of the ClassAction module are shown. ClassAction materials covering light and spectra concepts were utilized in multiple classrooms at 6 different institutions and the LSCI was delivered as a pretest and posttest to measure the gains in student understanding. A comparison of the gains achieved in these classes will be made against the national LSCI data. We will report on our investigation into correlations between gain and the extent of ClassAction usage. ClassAction materials are publicly available at http://astro.unl.edu. We would like to thank the NSF for funding under Grant Nos. 0404988 and 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.

  12. Exploring possible selves in a first-year physics foundation class: Engaging students by establishing relevance

    NASA Astrophysics Data System (ADS)

    Bennett, Dawn; Roberts, Lynne; Creagh, Christine

    2016-06-01

    Students often complain that they cannot see the relevance of what they are being taught in foundation physics classes. While revising and adjusting the curriculum and teaching are important, this study suggests it might also be useful to help students view their learning in relation to their future career aspirations. This paper reports on a study conducted with first-year students enrolled in a compulsory foundation physics unit with a history of low pass rates. Working within a "possible selves" framework, activities were designed to help students position their learning in relation to possible future lives and careers. Two cohorts of students (N =93 ) engaged in an intensive workshop comprising multiple activities relating to self and career. Self-reflection worksheets were analyzed using content analysis. The results indicate that students experience immediate benefits from these activities through self-reflection on the current self, future possible professional selves, and the role of current studies in narrowing the gap between the two.

  13. 21 CFR 509.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., and action levels. 509.4 Section 509.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 509.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  14. 21 CFR 109.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., and action levels. 109.4 Section 109.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 109.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  15. 21 CFR 509.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., and action levels. 509.4 Section 509.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 509.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  16. 21 CFR 109.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., and action levels. 109.4 Section 109.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 109.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  17. 21 CFR 509.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., and action levels. 509.4 Section 509.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 509.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  18. 21 CFR 109.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., and action levels. 109.4 Section 109.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 109.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  19. 21 CFR 509.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., and action levels. 509.4 Section 509.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF..., regulatory limits, and action levels. (a) When appropriate under the criteria of § 509.6, a tolerance for an... in subpart B of this part under the provisions of section 406 of the act. A tolerance may...

  20. EFFICIENTLY ESTABLISHING CONCEPTS OF INFERENTIAL STATISTICS AND HYPOTHESIS DECISION MAKING THROUGH CONTEXTUALLY CONTROLLED EQUIVALENCE CLASSES

    PubMed Central

    Fienup, Daniel M; Critchfield, Thomas S

    2010-01-01

    Computerized lessons that reflect stimulus equivalence principles were used to teach college students concepts related to inferential statistics and hypothesis decision making. Lesson 1 taught participants concepts related to inferential statistics, and Lesson 2 taught them to base hypothesis decisions on a scientific hypothesis and the direction of an effect. Lesson 3 taught the conditional influence of inferential statistics over decisions regarding the scientific and null hypotheses. Participants entered the study with low scores on the targeted skills and left the study demonstrating a high level of accuracy on these skills, which involved mastering more relations than were taught formally. This study illustrates the efficiency of equivalence-based instruction in establishing academic skills in sophisticated learners. PMID:21358904

  1. New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

    PubMed Central

    Tsiang, Manuel; Jones, Gregg S.; Niedziela-Majka, Anita; Kan, Elaine; Lansdon, Eric B.; Huang, Wayne; Hung, Magdeleine; Samuel, Dharmaraj; Novikov, Nikolai; Xu, Yili; Mitchell, Michael; Guo, Hongyan; Babaoglu, Kerim; Liu, Xiaohong; Geleziunas, Romas; Sakowicz, Roman

    2012-01-01

    tert-Butoxy-(4-phenyl-quinolin-3-yl)-acetic acids (tBPQA) are a new class of HIV-1 integrase (IN) inhibitors that are structurally distinct from IN strand transfer inhibitors but analogous to LEDGINs. LEDGINs are a class of potent antiviral compounds that interacts with the lens epithelium-derived growth factor (LEDGF) binding pocket on IN and were identified through competition binding against LEDGF. LEDGF tethers IN to the host chromatin and enables targeted integration of viral DNA. The prevailing understanding of the antiviral mechanism of LEDGINs is that they inhibit LEDGF binding to IN, which prevents targeted integration of HIV-1. We showed that in addition to the properties already known for LEDGINs, the binding of tBPQAs to the IN dimer interface inhibits IN enzymatic activity in a LEDGF-independent manner. Using the analysis of two long terminal repeat junctions in HIV-infected cells, we showed that the inhibition by tBPQAs occurs at or prior to the viral DNA 3′-processing step. Biochemical studies revealed that this inhibition operates by compound-induced conformational changes in the IN dimer that prevent proper assembly of IN onto viral DNA. For the first time, tBPQAs were demonstrated to be allosteric inhibitors of HIV-1 IN displaying a dual mode of action: inhibition of IN-viral DNA assembly and inhibition of IN-LEDGF interaction. PMID:22535962

  2. New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.

    PubMed

    Tsiang, Manuel; Jones, Gregg S; Niedziela-Majka, Anita; Kan, Elaine; Lansdon, Eric B; Huang, Wayne; Hung, Magdeleine; Samuel, Dharmaraj; Novikov, Nikolai; Xu, Yili; Mitchell, Michael; Guo, Hongyan; Babaoglu, Kerim; Liu, Xiaohong; Geleziunas, Romas; Sakowicz, Roman

    2012-06-15

    tert-Butoxy-(4-phenyl-quinolin-3-yl)-acetic acids (tBPQA) are a new class of HIV-1 integrase (IN) inhibitors that are structurally distinct from IN strand transfer inhibitors but analogous to LEDGINs. LEDGINs are a class of potent antiviral compounds that interacts with the lens epithelium-derived growth factor (LEDGF) binding pocket on IN and were identified through competition binding against LEDGF. LEDGF tethers IN to the host chromatin and enables targeted integration of viral DNA. The prevailing understanding of the antiviral mechanism of LEDGINs is that they inhibit LEDGF binding to IN, which prevents targeted integration of HIV-1. We showed that in addition to the properties already known for LEDGINs, the binding of tBPQAs to the IN dimer interface inhibits IN enzymatic activity in a LEDGF-independent manner. Using the analysis of two long terminal repeat junctions in HIV-infected cells, we showed that the inhibition by tBPQAs occurs at or prior to the viral DNA 3'-processing step. Biochemical studies revealed that this inhibition operates by compound-induced conformational changes in the IN dimer that prevent proper assembly of IN onto viral DNA. For the first time, tBPQAs were demonstrated to be allosteric inhibitors of HIV-1 IN displaying a dual mode of action: inhibition of IN-viral DNA assembly and inhibition of IN-LEDGF interaction. PMID:22535962

  3. 21 CFR 109.4 - Establishment of tolerances, regulatory limits, and action levels.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD FOR HUMAN CONSUMPTION AND FOOD-PACKAGING MATERIAL General Provisions § 109.4 Establishment of tolerances... may be established in subpart D of this part to identify a food containing a naturally...

  4. Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes

    PubMed Central

    Mohamad Zobir, Siti Zuraidah; Mohd Fauzi, Fazlin; Liggi, Sonia; Drakakis, Georgios; Fu, Xianjun; Fan, Tai-Ping; Bender, Andreas

    2016-01-01

    Traditional Chinese medicine (TCM) still needs more scientific rationale to be proven for it to be accepted further in the West. We are now in the position to propose computational hypotheses for the mode-of-actions (MOAs) of 45 TCM therapeutic action (sub)classes from in silico target prediction algorithms, whose target was later annotated with Kyoto Encyclopedia of Genes and Genomes pathway, and to discover the relationship between them by generating a hierarchical clustering. The results of 10,749 TCM compounds showed 183 enriched targets and 99 enriched pathways from Estimation Score ≤ 0 and ≥ 5% of compounds/targets in a (sub)class. The MOA of a (sub)class was established from supporting literature. Overall, the most frequent top three enriched targets/pathways were immune-related targets such as tyrosine-protein phosphatase nonreceptor type 2 (PTPN2) and digestive system such as mineral absorption. We found two major protein families, G-protein coupled receptor (GPCR), and protein kinase family contributed to the diversity of the bioactivity space, while digestive system was consistently annotated pathway motif, which agreed with the important treatment principle of TCM, “the foundation of acquired constitution” that includes spleen and stomach. In short, the TCM (sub)classes, in many cases share similar targets/pathways despite having different indications. PMID:26989424

  5. Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes.

    PubMed

    Mohamad Zobir, Siti Zuraidah; Mohd Fauzi, Fazlin; Liggi, Sonia; Drakakis, Georgios; Fu, Xianjun; Fan, Tai-Ping; Bender, Andreas

    2016-01-01

    Traditional Chinese medicine (TCM) still needs more scientific rationale to be proven for it to be accepted further in the West. We are now in the position to propose computational hypotheses for the mode-of-actions (MOAs) of 45 TCM therapeutic action (sub)classes from in silico target prediction algorithms, whose target was later annotated with Kyoto Encyclopedia of Genes and Genomes pathway, and to discover the relationship between them by generating a hierarchical clustering. The results of 10,749 TCM compounds showed 183 enriched targets and 99 enriched pathways from Estimation Score ≤ 0 and ≥ 5% of compounds/targets in a (sub)class. The MOA of a (sub)class was established from supporting literature. Overall, the most frequent top three enriched targets/pathways were immune-related targets such as tyrosine-protein phosphatase nonreceptor type 2 (PTPN2) and digestive system such as mineral absorption. We found two major protein families, G-protein coupled receptor (GPCR), and protein kinase family contributed to the diversity of the bioactivity space, while digestive system was consistently annotated pathway motif, which agreed with the important treatment principle of TCM, "the foundation of acquired constitution" that includes spleen and stomach. In short, the TCM (sub)classes, in many cases share similar targets/pathways despite having different indications. PMID:26989424

  6. The QUIPPED Project: Exploring Relevance and Rigor of Action Research Using Established Principles and Criteria

    ERIC Educational Resources Information Center

    Chapman, Christine; Paterson, Margo; Medves, Jennifer M.

    2011-01-01

    This paper is the last in a series of three manuscripts published in the TQR journal over the past few years. This work is part of a larger program of research that has been carried out by a team of researchers detailing various aspects of a three year action research project carried out from 2005 and 2008. This particular paper addresses issues…

  7. The Two-Peptide (Class-IIb) Bacteriocins: Genetics, Biosynthesis, Structure, and Mode of Action

    NASA Astrophysics Data System (ADS)

    Nissen-Meyer, Jon; Oppegård, Camilla; Rogne, Per; Haugen, Helen Sophie; Kristiansen, Per Eugen

    The two-peptide (class-IIb) bacteriocins consist of two different peptides, both of which are required to obtain high antimicrobial activity. These bacteriocins kill target-cells by inducing membrane-leakage and they seem to display some specificity with respect to the molecules they transfer across membranes. The genes encoding the two peptides of two-peptide bacteriocins are next to each other on the same operon. In the same or a nearby operon are genes encoding (i) the immunity protein that protects the bacteriocin-producer from its own bacteriocin, (ii) a dedicated ABC-transporter that exports the bacteriocin from cells and cleaves off the N-terminal bacteriocin leader sequence, and (iii) an accessory protein whose exact function has not been fully clarified. Some two-peptide bacteriocins appear to be produced constitutively, whereas the production of other two-peptide bacteriocins is regulated through a three-component regulatory system that consists of a peptide pheromone, a membrane-associated histidine protein kinase, and response regulators. It has recently been proposed that the two peptides of (some) two-peptide bacteriocins may form a membrane-penetrating helix-helix structure involving helix-helix interacting GxxxG-motifs present in all currently characterized two-peptide bacteriocins. It has also been suggested that the helix-helix structure interacts with an integrated membrane (transport) protein, thus inducing a conformational change in the protein, which in turn causes membrane-leakage. This proposed mode-of-action is similar to that of the pediocin-like (class-IIa) bacteriocins and lactococcin A, which bind to a part of the mannose phosphotransferase permease that is embedded in the cell membrane, thereby altering the conformation of the ­permease in a manner that causes membrane-leakage and cell death.

  8. Auxiliary field loop expansion of the effective action for a class of stochastic partial differential equations

    NASA Astrophysics Data System (ADS)

    Cooper, Fred; Dawson, John F.

    2016-02-01

    We present an alternative to the perturbative (in coupling constant) diagrammatic approach for studying stochastic dynamics of a class of reaction diffusion systems. Our approach is based on an auxiliary field loop expansion for the path integral representation for the generating functional of the noise induced correlation functions of the fields describing these systems. The systems we consider include Langevin systems describable by the set of self interacting classical fields ϕi(x , t) in the presence of external noise ηi(x , t) , namely (∂t - ν∇2) ϕ - F [ ϕ ] = η, as well as chemical reaction annihilation processes obtained by applying the many-body approach of Doi-Peliti to the Master Equation formulation of these problems. We consider two different effective actions, one based on the Onsager-Machlup (OM) approach, and the other due to Janssen-deGenneris based on the Martin-Siggia-Rose (MSR) response function approach. For the simple models we consider, we determine an analytic expression for the Energy landscape (effective potential) in both formalisms and show how to obtain the more physical effective potential of the Onsager-Machlup approach from the MSR effective potential in leading order in the auxiliary field loop expansion. For the KPZ equation we find that our approximation, which is non-perturbative and obeys broken symmetry Ward identities, does not lead to the appearance of a fluctuation induced symmetry breakdown. This contradicts the results of earlier studies.

  9. A Sound Research Base for Beginning Teacher Education: Robust Hope, Action Policy Analysis and "Top of the Class"

    ERIC Educational Resources Information Center

    Singh, Michael

    2007-01-01

    This paper focuses on the recommendations of "Top of the class," the February 2007 report of an inquiry into teacher education conducted by the Australian House of Representatives Standing Committee on Education and Vocational Training. To do this action policy analysis, it presents Raymond Williams' dictum of "making hope practical" through five…

  10. Implementing the Affordable Care Act: State Action to Establish SHOP Marketplaces.

    PubMed

    Dash, Sarah J; Lucia, Kevin W; Thomas, Amy

    2014-03-01

    The Affordable Care Act seeks to help small employers offer coverage by reforming the small-group market and establishing Small Business Health Options Program (SHOP) marketplaces. Seventeen states and the District of Columbia chose to operate their own SHOP marketplaces in 2014, with the federal government operating the SHOP marketplace in 33 states. This brief examines state decisions to enhance the value of SHOP marketplaces for small employers and finds that most have set predictable participation and eligibility requirements and will offer a competitive choice of insurers and plans. States also are seeking to facilitate small employers' shopping experience through online tools and access to personalized assistance. While not all SHOP marketplaces are yet functioning as intended, their establishment offers an opportunity to identify successful strategies for improving the affordability and accessibility of coverage for small employers. PMID:26259258

  11. [Successor establishment in familiy business as field of action in health promotion].

    PubMed

    Hetzel, C; Holzer, M

    2014-10-01

    Successor establishment in familiy business may lead to interpersonal and intrapsychological conflicts and is mostly a transition to retirement. This may have a negative impact on the senior's health. The "Sozialversicherung für Landwirtschaft, Forsten und Gartenbau (SVLFG)" reacts with an intervention of several days duration. Evaluation aim is measuring participants changes in specific activities and confidence on successor establishment and retirement indicating mental health stabilisation. The method comprises a panel of intervention group (I, n=61) and comparison group (V, n=28) randomly selected, structurally similar and parallelised to point of transfer. Retirement activities significantly rise in I (p=0.001, Cohen's d=0.48) and are steady in V (p=0.54) after one year. Level of confidence is equal in both groups and steady but strongly indicating response shift in I. Intervention activates targeted activities and improves confidence at least qualitatively in a field that has hardly been researched. PMID:25001902

  12. Patterns of stomatal conductance among blue oak (Quercus douglasii) size classes and populations: implications for seedling establishment.

    PubMed

    Matzner, Steven L; Rice, Kevin J; Richards, James H

    2003-08-01

    Quercus douglasii Hook. & Arn. (blue oak) is a deciduous white oak that is currently failing to regenerate throughout much of its range in California, USA. Patterns of water use were observed in adult trees, saplings and seedlings to determine if ontogenetic changes in water use occur, which might be important in the establishment of this long-lived perennial species in a Mediterranean-type system. Seasonal and diurnal stomatal conductance (g(s)), late-season predawn xylem water potentials (Psi(pre)), carbon isotopic ratio (delta(13)C) and soil water status were compared among the three size classes at three sites differing in mean precipitation and soil water characteristics. Comparisons were also made between microsites with and without regeneration (defined by the presence or absence of saplings). Overall patterns of water use were consistent among the three sites, except that, at the site with the highest rainfall, Q. douglasii plants had higher g(s) and more positive Psi(pre) values. Although no differences in water use patterns were found between regeneration and non-regeneration microsites, the observed ontogenetic differences in water use may have important implications for Q. douglasii establishment. Compared with adult trees and saplings, seedlings had higher gas exchange rates during periods of high soil water content (early in the season and in the morning). Seedling g(s) was correlated with percent extractable soil water (ESW) throughout the season; adult tree and sapling g(s) was correlated with ESW between June and September. Despite experiencing greater water stress (indicated by more negative Psi(pre) values) than older trees, seedlings had more negative delta(13)C values, implying lower water-use efficiencies. PMID:12839731

  13. Evolution in Action, a Case Study Based Advanced Biology Class at Spelman College

    ERIC Educational Resources Information Center

    Pai, Aditi

    2009-01-01

    The Biology department at Spelman, a historically black women's college has undertaken a major curriculum revision in the last few years. A primary goal of this revision is to increase the breadth of topics in biology classes. Historically, classes in the areas of ecology and evolution have been underrepresented whereas Spelman has always offered…

  14. Middle- and Upper-Middle-Class Parent Action for Urban Public Schools: Promise or Paradox?

    ERIC Educational Resources Information Center

    Posey, Linn

    2012-01-01

    Background/Context: Recent trends suggest that middle-class parents may be a growing constituency in urban public schools and districts. Within the burgeoning literature on the middle class in urban public schools, most scholars have focused on parents' goals and orientations and/or the consequences of parental involvement in classroom and school…

  15. 31 CFR 30.8 - Q-8: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Q-8: What actions are necessary for a TARP recipient to comply with the standards established under section 111(b)(3)(B) of EESA (the... the Treasury TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.8 Q-8: What actions...

  16. Views and Workshops of a Master's Class in Intercultural Competence: Mill's Model of Intercultural Action

    ERIC Educational Resources Information Center

    Ioannitou, Gina

    2010-01-01

    This paper is the result of a participative process in which the students of the Master's Degree "Didactique des Langues" (foreign language didactics) at Universite du Maine (Le Mans, France) explored through whole-class activities the field of intercultural dialog and intercultural competence teaching. Our approach to intercultural teaching…

  17. The Facebook-in-Action: Challenging, Harnessing and Enhancing Students Class Assignments and Projects

    ERIC Educational Resources Information Center

    Saifudin, Adam Mohd; Yacob, Aizan; Saad, Rohaizah

    2016-01-01

    Issues of universities students harnessing and capitalizing the usage of Facebook for their own learning capabilities and effective thinking is always the focus of education scholars, in assessing the quality class assignments and projects produced by them. Therefore, Facebook is now becoming unbearable influence since the internet activation in…

  18. 18 CFR 707.8 - Typical classes of action requiring similar treatment under NEPA.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Typical classes of... Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) Water... submittal of regional water resources management plans (comprehensive, coordinated, joint plans or...

  19. 18 CFR 707.8 - Typical classes of action requiring similar treatment under NEPA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Typical classes of... Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) Water... submittal of regional water resources management plans (comprehensive, coordinated, joint plans or...

  20. Inhibition of Voltage-Gated Calcium Channels as Common Mode of Action for (Mixtures of) Distinct Classes of Insecticides

    PubMed Central

    Meijer, Marieke; Dingemans, Milou M.L.; van den Berg, Martin; Westerink, Remco H.S.

    2014-01-01

    Humans are exposed to distinct structural classes of insecticides with different neurotoxic modes of action. Because calcium homeostasis is essential for proper neuronal function and development, we investigated the effects of insecticides from different classes (pyrethroid: (α-)cypermethrin; organophosphate: chlorpyrifos; organochlorine: endosulfan; neonicotinoid: imidacloprid) and mixtures thereof on the intracellular calcium concentration ([Ca2+]i). Effects of acute (20 min) exposure to (mixtures of) insecticides on basal and depolarization-evoked [Ca2+]i were studied in vitro with Fura-2-loaded PC12 cells and high resolution single-cell fluorescence microscopy. The data demonstrate that cypermethrin, α-cypermethrin, endosulfan, and chlorpyrifos concentration-dependently decreased depolarization-evoked [Ca2+]i, with 50% (IC50) at 78nM, 239nM, 250nM, and 899nM, respectively. Additionally, acute exposure to chlorpyrifos or endosulfan (10μM) induced a modest increase in basal [Ca2+]i, amounting to 68 ± 8nM and 53 ± 8nM, respectively. Imidacloprid did not disturb basal or depolarization-evoked [Ca2+]i at 10μM. Following exposure to binary mixtures, effects on depolarization-evoked [Ca2+]i were within the expected effect additivity range, whereas the effect of the tertiary mixture was less than this expected additivity effect range. These results demonstrate that different types of insecticides inhibit depolarization-evoked [Ca2+]i in PC12 cells by inhibiting voltage-gated calcium channels (VGCCs) in vitro at concentrations comparable with human occupational exposure levels. Moreover, the effective concentrations in this study are below those for earlier described modes of action. Because inhibition of VGCCs appears to be a common and potentially additive mode of action of several classes of insecticides, this target should be considered in neurotoxicity risk assessment studies. PMID:24913802

  1. Identification and Characterization of Novel Classes of Macrophage Migration Inhibitory Factor (MIF) Inhibitors with Distinct Mechanisms of Action*

    PubMed Central

    Ouertatani-Sakouhi, Hajer; El-Turk, Farah; Fauvet, Bruno; Cho, Min-Kyu; Pinar Karpinar, Damla; Le Roy, Didier; Dewor, Manfred; Roger, Thierry; Bernhagen, Jürgen; Calandra, Thierry; Zweckstetter, Markus; Lashuel, Hilal A.

    2010-01-01

    Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, is considered an attractive therapeutic target in multiple inflammatory and autoimmune disorders. In addition to its known biologic activities, MIF can also function as a tautomerase. Several small molecules have been reported to be effective inhibitors of MIF tautomerase activity in vitro. Herein we employed a robust activity-based assay to identify different classes of novel inhibitors of the catalytic and biological activities of MIF. Several novel chemical classes of inhibitors of the catalytic activity of MIF with IC50 values in the range of 0.2–15.5 μm were identified and validated. The interaction site and mechanism of action of these inhibitors were defined using structure-activity studies and a battery of biochemical and biophysical methods. MIF inhibitors emerging from these studies could be divided into three categories based on their mechanism of action: 1) molecules that covalently modify the catalytic site at the N-terminal proline residue, Pro1; 2) a novel class of catalytic site inhibitors; and finally 3) molecules that disrupt the trimeric structure of MIF. Importantly, all inhibitors demonstrated total inhibition of MIF-mediated glucocorticoid overriding and AKT phosphorylation, whereas ebselen, a trimer-disrupting inhibitor, additionally acted as a potent hyperagonist in MIF-mediated chemotactic migration. The identification of biologically active compounds with known toxicity, pharmacokinetic properties, and biological activities in vivo should accelerate the development of clinically relevant MIF inhibitors. Furthermore, the diversity of chemical structures and mechanisms of action of our inhibitors makes them ideal mechanistic probes for elucidating the structure-function relationships of MIF and to further determine the role of the oligomerization state and catalytic activity of MIF in regulating the function(s) of MIF in health and disease. PMID:20516071

  2. 7 CFR 1940.318 - Completing environmental assessments for Class II actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... consideration of the application until such problem is alleviated. (g) Similarly, throughout the assessment... action will result in postponement of further consideration of the application until such problem is... pending application for at least 15 days from the date the notification is last published. If comments...

  3. 78 FR 10099 - Implementation of the Middle Class Tax Relief and Job Creation Act of 2012; Establishment of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ..., (77 FR 71131). The amended rules are necessary to implement the enforcement provisions of the Middle... the Commission's rules, which were published in the Federal Register on November 29, 2012, 77 FR 71131... COMMISSION 47 CFR Part 1 Implementation of the Middle Class Tax Relief and Job Creation Act of...

  4. 78 FR 12967 - Establishment of Class A TV Service and Cable Television Rate Regulation; Cost of Service Rules...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... for the sections listed: 73.1545(e)-66 FR 21681, May 1, 2001 76.922(i)(6)(i) and (i)(7)-61 FR 9367... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS... Communications Commission. ACTION: Final rule; clarification and announcement of effective dates. SUMMARY:...

  5. Acceleration of electrons under the action of petawatt-class laser pulses onto foam targets

    NASA Astrophysics Data System (ADS)

    Pugachev, L. P.; Andreev, N. E.; Levashov, P. R.; Rosmej, O. N.

    2016-09-01

    Optimization study for future experiments on interaction of petawatt laser pulses with foam targets was done by 3D PIC simulations. Densities in the range 0.5nc-nc and thicknesses in the range 100 - 500 μm of the targets were considered corresponding to those which are currently available. It is shown that heating of electrons mainly occurs under the action of the ponderomotive force of a laser pulse in which amplitude increases up to three times because of self-focusing effect in underdense plasma. Accelerated electrons gain additional energy directly from the high-frequency laser field at the betatron resonance in the emerging plasma density channels. For thicker targets a higher number of electrons with higher energies are obtained. The narrowing of the angular distribution of electrons for thicker targets is explained by acceleration in multiple narrow filaments. Obtained energies of accelerated electrons can be approximated by Maxwell distribution with the temperature 8.5 MeV. The charge carried by electrons with energies higher than 30 MeV is about 30 nC, that is 3-4 order of magnitude higher than the charge predicted by the ponderomotive scaling for the incident laser amplitude.

  6. A new class of furoxan derivatives as NO donors: mechanism of action and biological activity.

    PubMed Central

    Ferioli, R; Folco, G C; Ferretti, C; Gasco, A M; Medana, C; Fruttero, R; Civelli, M; Gasco, A

    1995-01-01

    1. The mechanism of action and biological activity of a series of R-substituted and di-R-substituted phenylfuroxans is reported. 2. Maximal potency as vasodilators on rabbit aortic rings, precontracted with noradrenaline (1 microM), was shown by phenyl-cyano isomers and by the 3,4-dicyanofuroxan, characterized by a potency ratio 3-10 fold higher than glyceryl trinitrate (GTN). This effect was reduced upon coincubation with methylene blue or oxyhaemoglobin (10 microM). 3. The furoxan derivatives showing maximal potency as vasodilators were also able to inhibit collagen-induced platelet aggregation, with IC50 values in the sub-micromolar range. 4. The furoxan derivatives were able to stimulate partially purified, rat lung soluble guanylate cyclase; among the most active compounds, the 3-R-substituted isomers displayed a higher level of stimulatory effect than the 4-R analogues. 5. Solutions (0.1 mM) of all the tested furoxans, prepared using 50 mM phosphate buffer, pH 7.4, (diluting 10 mM DMSO stock solutions) did not release nitric oxide (NO) spontaneously; however in presence of 5 mM L-cysteine, a significant NO-releasing capacity was observed, which correlated significantly with their stimulation of the guanylate cyclase activity. PMID:7773542

  7. Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action

    PubMed Central

    Busch, A E; Eigenberger, B; Jurkiewicz, N K; Salata, J J; Pica, A; Suessbrich, H; Lang, F

    1998-01-01

    The class III antiarrhythmic azimilide has previously been shown to inhibit IKs and IKr in guinea-pig cardiac myocytes and IKs (minK) channels expressed in Xenopus oocytes. Because HERG channels underly the conductance IKr in human heart, the effects of azimilide on HERG channels expressed in Xenopus oocytes were the focus of the present study.In contrast to other well characterized HERG channel blockers, azimilide blockade was reverse use-dependent, i.e., the relative block and apparent affinity of azimilide decreased with an increase in channel activation frequency. Azimilide blocked HERG channels at 0.1 and 1 Hz with IC50 s of 1.4 μM and 5.2  μM respectively.In an envelope of tail test, HERG channel blockade increased with increasing channel activation, indicating binding of azimilide to open channels.Azimilide blockade of HERG channels expressed in Xenopus oocytes and IKr in mouse AT-1 cells was decreased under conditions of high [K+]e, whereas block of slowly activating IKs channels was not affected by changes in [K+]e.In summary, azimilide is a blocker of cardiac delayed rectifier channels, IKs and HERG. Because of the distinct effects of stimulation frequency and [K+]e on azimilide block of IKr and IKs channels, we conclude that the relative contribution of block of each of these cardiac delayed rectifier channels depends on heart frequency. [K+]e and regulatory status of the respective channels. PMID:9484850

  8. Human immunoglobulin class and IgG subclass regulation: dual action of interleukin-4.

    PubMed

    Kotowicz, K; Callard, R E

    1993-09-01

    Epstein-Barr virus (EBV) was used as a polyclonal human B cell mitogen to investigate the regulation of immunoglobulin class and IgG subclass responses by interleukin-4 (IL-4). Activation of tonsillar B cells with EBV resulted in an early peak of polyclonal immunoglobulin secretion between days 13 and 14 consisting of IgM, IgA, and IgG1, IgG2, IgG3 and IgG4, but not IgE. Addition of IL-4 to EBV-activated B cells at concentrations of 100 U/ml or greater induced the production of IgE and enhanced IgG4 secretion, but had no effect, or more often inhibited the other isotypes. In contrast, low concentrations of IL-4 (1-5 U/ml) significantly increased the production of IgM, IgA, IgG1, IgG2 and IgG3, but had no effect on IgG4 or IgE. The increase in immunoglobulin secretion obtained with low concentrations of IL-4 was found to occur only with high-density (resting) B cells, suggesting that IL-4 was not functioning simply as a late-acting differentiation factor. Low concentrations of IL-4 significantly increased IgG1, IgG2, IgG3, and IgA production by surface (s) IgM+ (sIgG-/sIgA-) B cells which is consistent with heavy chain switching. In some experiments, however, IL-4 enhanced IgM secretion by sIgM+ B cells, and IgA, IgG1, IgG2, IgG3 by sIgM- B cells, suggesting that it may have an additional B cell differentiation factor activity which was not isotype specific. The different effect of IL-4 at high and low concentrations were similar to those observed in B cell activation experiments, and may be due to the existence of high- and low-affinity IL-4 receptors. PMID:8396532

  9. Structure and mechanism of action of the hydroxy aryl aldehyde class of IRE1 endoribonuclease inhibitors

    PubMed Central

    Sanches, Mario; Duffy, Nicole M.; Talukdar, Manisha; Thevakumaran, Nero; Chiovitti, David; Canny, Marella D.; Lee, Kenneth; Kurinov, Igor; Uehling, David; Al-awar, Rima; Poda, Gennadiy; Prakesch, Michael; Wilson, Brian; Tam, Victor; Schweitzer, Colleen; Toro, Andras; Lucas, Julie L.; Vuga, Danka; Lehmann, Lynn; Durocher, Daniel; Zeng, Qingping; Patterson, John B.; Sicheri, Frank

    2014-01-01

    Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA substrates to re-establish ER homeostasis. Aromatic ring systems containing hydroxy-aldehyde moieties, termed hydroxy aryl aldehydes (HAA), selectively inhibit IRE1α RNase and thus represent a novel chemical series for therapeutic development. We solved crystal structures of murine IRE1α in complex with three HAA inhibitors. HAA inhibitors engage a shallow pocket at the RNase active site through pi-stacking interactions with His910 and Phe889, an essential Schiff base with Lys907 and a H-bond with Tyr892. Structure activity studies and mutational analysis of contact residues define the optimal chemical space of inhibitors and validate the inhibitor binding site. These studies lay the foundation for understanding both the biochemical and cellular functions of IRE1α using small molecule inhibitors and suggest new avenues for inhibitor design. PMID:25164867

  10. Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation

    PubMed Central

    Matsuoka, Shuji; Ishii, Yasuyuki; Nakao, Atsuhito; Abe, Masaaki; Ohtsuji, Naomi; Momose, Shuji; Jin, Hui; Arase, Hisashi; Sugimoto, Koichi; Nakauchi, Yusuke; Masutani, Hiroshi; Maeda, Michiyuki; Yagita, Hideo; Komatsu, Norio; Hino, Okio

    2016-01-01

    To develop a new therapeutic monoclonal Antibody (mAb) for Hodgkin lymphoma (HL), we immunized a BALB/c mouse with live HL cell lines, alternating between two HL cell lines. After hybridization, we screened the hybridoma clones by assessing direct cytotoxicity against a HL cell line not used for immunization. We developed this strategy for establishing mAb to reduce the risk of obtaining clonotypic mAb specific for single HL cell line. A newly established mouse anti-human mAb (4713) triggered cytoskeleton-dependent, but complement- and caspase-independent, cell death in HL cell lines, Burkitt lymphoma cell lines, and advanced adult T-cell leukemia cell lines. Intravenous injection of mAb 4713 in tumor-bearing SCID mice improved survival significantly. mAb 4713 was revealed to be a mouse anti-human pan-HLA class II mAb. Treatment with this mAb induced the formation of large pores on the surface of target lymphoma cells within 30 min. This finding suggests that the cell death process induced by this anti-pan HLA-class II mAb may involve the same death signals stimulated by a cytolytic anti-pan MHC class I mAb that also induces large pore formation. This multifaceted study supports the therapeutic potential of mAb 4713 for various forms of lymphoma. PMID:27028595

  11. The teacher's role in the establishment of whole-class dialogue in a fifth grade science classroom using argument-based inquiry

    NASA Astrophysics Data System (ADS)

    Benus, Matthew J.

    The purpose of this study was to examine the patterns of dialogue that were established and emerged in one experienced fifth-grade science teacher's classroom that used the argument-based inquiry (ABI) and the ways in which these patterns of dialogue and consensus-making were used toward the establishment of a grasp of science practice. Most current studies on ABI agree that it does not come naturally and is only acquired through practice. Additionally, the quality of dialogue is also understood to be an important link in support of student learning. Few studies have examined the ways in which a teacher develops whole-class dialogue over time and the ways in which patterns of dialogue shift over time. The research questions that guided this study were: (1) What were the initial whole-class dialogue patterns established by a fifth-grade science teacher who engaged in ABI? (2) How did the science teacher help to refine whole-class dialogue to support the agreeability of ideas constructed over time? This eighteen week study that took place in a small city of less than 15,000 in Midwestern United States was grounded in interactive constructivism, and utilized a qualitative design method to identify the ways in which an experienced fifth-grade science teacher developed whole-class dialogue and used consensus-making activities to develop the practice of ABI with his students. The teacher in this study used the Science Writing Heuristic (SWH) approach to ABI with twenty-one students who had no previous experience engaging in ABI. This teacher with 10 of years teaching experience was purposefully selected because he was proficient and experienced in practicing ABI. Multiple sources of data were collected, including classroom video with transcriptions, semi-structured interviews, after lesson conversations, and researcher's field notes. Data analysis used a basic qualitative approach. The results showed (1) that the teacher principally engaged in three forms of whole-class

  12. Implementing on-Campus Microteaching to Elicit Preservice Teachers' Reflection on Teaching Actions: Fresh Perspective on an Established Practice

    ERIC Educational Resources Information Center

    Amobi, Funmi A.; Irwin, Leslie

    2009-01-01

    This article calls for renewed emphasis on the use of on-campus microteaching to facilitate simultaneously preservice teachers' performance of effective teaching skills and their capability to reflect meaningfully on their emergent teaching actions. In making a case for greater focus on the implementation of microteaching in preservice teacher…

  13. A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients

    PubMed Central

    Ligocki, Ann J.; Rivas, Jacqueline R.; Rounds, William H.; Guzman, Alyssa A.; Li, Min; Spadaro, Melania; Lahey, Lauren; Chen, Ding; Henson, Paul M.; Graves, Donna; Greenberg, Benjamin M.; Frohman, Elliot M.; Sally Ward, E.; Robinson, William; Meinl, Edgar; White, Charles L.; Stowe, Ann M.

    2015-01-01

    *These authors contributed equally to the work in this manuscript.We have previously identified a distinct class of antibodies expressed by B cells in the cerebrospinal fluid (CSF) of early and established relapsing remitting multiple sclerosis (RRMS) patients that is not observed in healthy donors. These antibodies contain a unique pattern of mutations in six codons along VH4 antibody genes that we termed the antibody gene signature (AGS). In fact, patients who have such B cells in their CSF are identified as either having RRMS or developing RRMS in the future. As mutations in antibody genes increase antibody affinity for particular antigens, the goal for this study was to investigate whether AGS+ antibodies bind to brain tissue antigens. Single B cells were isolated from the CSF of 10 patients with early or established RRMS. We chose 32 of these B cells that expressed antibodies enriched for the AGS for further study. We generated monoclonal full-length recombinant human antibodies (rhAbs) and used both immunological assays and immunohistochemistry to investigate the capacity of these AGS+ rhAbs to bind brain tissue antigens. AGS+ rhAbs did not recognize myelin tracts in the corpus callosum. Instead, AGS+ rhAbs recognized neuronal nuclei and/or astrocytes, which are prevalent in the cortical gray matter. This pattern was unique to the AGS+ antibodies from early and established RRMS patients, as AGS+ antibodies from an early neuromyelitis optica patient did not display the same reactivity. Prevalence of CSF-derived B cells expressing AGS+ antibodies that bind to these cell types may be an indicator of gray matter-directed autoimmunity in early and established RRMS patients. PMID:26489686

  14. An Action Research Report on Applying Co-Operative Learning Techniques in an Intensive English Reading Class in China

    ERIC Educational Resources Information Center

    Fu, Xiao

    2013-01-01

    This study is to examine whether the implementation of CL in an intensive reading class has a positive effect on improving the passive situation of students, whether it helps activate their enthusiasm for and ease their anxiety of participation in language class activities, and whether it is helpful to their improvement of English proficiency. The…

  15. The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.

    PubMed

    Baeg, Gyeong-Hun; Selva, Erica M; Goodman, Robyn M; Dasgupta, Ramanuj; Perrimon, Norbert

    2004-12-01

    We have examined the respective contribution of Heparan Sulfate Proteoglycans (HSPGs) and Frizzled (Fz) proteins in the establishment of the Wingless (Wg) morphogen gradient. From the analysis of mutant clones of sulfateless/N-deacetylase-sulphotransferase in the wing imaginal disc, we find that lack of Heparan Sulfate (HS) causes a dramatic reduction of both extracellular and intracellular Wg in receiving cells. Our studies, together with others [Kirkpatrick, C.A., Dimitroff, B.D., Rawson, J.M., Selleck, S.B., 2004. Spatial regulation of Wingless morphogen distribution and signalling by Dally-like protein. Dev. Cell (in press)], reveals that the Glypican molecule Dally-like Protein (Dlp) is associated with both negative and positive roles in Wg short- and long-range signaling, respectively. In addition, analyses of the two Fz proteins indicate that the Fz and DFz2 receptors, in addition to transducing the signal, modulate the slope of the Wg gradient by regulating the amount of extracellular Wg. Taken together, our analysis illustrates how the coordinated activities of HSPGs and Fz/DFz2 shape the Wg morphogen gradient. PMID:15531366

  16. 10 CFR 1021.410 - Application of categorical exclusions (classes of actions that normally do not require EAs or EISs).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... presented by specific proposals, such as scientific controversy about the environmental effects of the... proposal is not “connected” (40 CFR 1508.25(a)(1)) to other actions with potentially significant impacts, is not related to other proposed actions with cumulatively significant impacts (40 CFR...

  17. 10 CFR 1021.410 - Application of categorical exclusions (classes of actions that normally do not require EAs or EISs).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... presented by specific proposals, such as scientific controversy about the environmental effects of the... proposal is not “connected” (40 CFR 1508.25(a)(1)) to other actions with potentially significant impacts, is not related to other proposed actions with cumulatively significant impacts (40 CFR...

  18. The Confluence of Race, Gender, and Class among Community College Students: Assessing Attitudes toward Affirmative Action in College Admissions

    ERIC Educational Resources Information Center

    Zamani-Gallaher, Eboni M.

    2007-01-01

    This article examines the attitudes of baccalaureate aspiring community college students with regard to affirmative action in college admissions. Using data from UCLA's Cooperative Institutional Research Program (CIRP) Annual Freshman Year Survey, the study assessed determinants of approval or disapproval of affirmative action for 20,339 community…

  19. Promiscuous Actions of Small Molecule Inhibitors of the Protein Kinase D-Class IIa HDAC Axis in Striated Muscle

    PubMed Central

    Lemon, Douglas D.; Harrison, Brooke C.; Horn, Todd R.; Stratton, Matthew S.; Ferguson, Bradley S.; Wempe, Michael F.; McKinsey, Timothy A.

    2015-01-01

    PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors of class IIa HDAC and PKD catalytic activity, respectively. We describe unanticipated effects of these compounds. MC1568 failed to inhibit class IIa HDAC catalytic activity in vitro, and exerted divergent effects on skeletal muscle differentiation compared to a bona fide inhibitor of these HDACs. In cardiomyocytes, Gö-6976 triggered calcium signaling and activated stress-inducible kinases. Based on these findings, caution is warranted when employing MC1568 and Gö-6976 as pharmacological tool compounds to assess functions of class IIa HDACs and PKD. PMID:25816750

  20. Social Class Differences in Secular Trends in Established Coronary Risk Factors over 20 Years: A Cohort Study of British Men from 1978–80 to 1998–2000

    PubMed Central

    Ramsay, Sheena E.; Whincup, Peter H.; Hardoon, Sarah L.; Lennon, Lucy T.; Morris, Richard W.; Wannamethee, S. G.

    2011-01-01

    Background Coronary heart disease (CHD) mortality in the UK since the late 1970s has declined more markedly among higher socioeconomic groups. However, little is known about changes in coronary risk factors in different socioeconomic groups. This study examined whether changes in established coronary risk factors in Britain over 20 years between 1978–80 and 1998–2000 differed between socioeconomic groups. Methods and Findings A socioeconomically representative cohort of 7735 British men aged 40–59 years was followed-up from 1978–80 to 1998–2000; data on blood pressure (BP), cholesterol, body mass index (BMI) and cigarette smoking were collected at both points in 4252 survivors. Social class was based on longest-held occupation in middle-age. Compared with men in non-manual occupations, men in manual occupations experienced a greater increase in BMI (mean difference = 0.33 kg/m2; 95%CI 0.14–0.53; p for interaction = 0.001), a smaller decline in non-HDL cholesterol (difference in mean change = 0.18 mmol/l; 95%CI 0.11–0.25, p for interaction≤0.0001) and a smaller increase in HDL cholesterol (difference in mean change = 0.04 mmol/l; 95%CI 0.02–0.06, p for interaction≤0.0001). However, mean systolic BP declined more in manual than non-manual groups (difference in mean change = 3.6; 95%CI 2.1–5.1, p for interaction≤0.0001). The odds of being a current smoker in 1978–80 and 1998–2000 did not differ between non-manual and manual social classes (p for interaction = 0.51). Conclusion Several key risk factors for CHD and type 2 diabetes showed less favourable changes in men in manual occupations. Continuing priority is needed to improve adverse cardiovascular risk profiles in socially disadvantaged groups in the UK. PMID:21603647

  1. Action Research for School Improvement: Studies on Able, Gifted and Talented Learners, Homework and White Working-Class Pupils

    ERIC Educational Resources Information Center

    Riggall, Anna, Ed.; Churches, Richard, Ed.; Elwick, Alex, Ed.

    2014-01-01

    This report is based on seven action research projects undertaken by teachers in CfBT academies in the school year 2012/13. The schools received research support that included training in research methods and undertook a smallscale research project within one of three thematic strands. Schools chose the themes for their research themselves and…

  2. 10 CFR 1021.410 - Application of categorical exclusions (classes of actions that normally do not require EAs or EISs).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... proposal is not connected to other actions with potentially significant impacts (40 CFR 1508.25(a)(1)), is... CFR 1508.27(b)(7)), and is not precluded by 40 CFR 1506.1 or § 1021.211 of this part concerning... pursuant to FOIA. (See also 10 CFR 1021.340.) (f) Proposed recurring activities to be undertaken during...

  3. 10 CFR 1021.410 - Application of categorical exclusions (classes of actions that normally do not require EAs or EISs).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... proposal is not connected to other actions with potentially significant impacts (40 CFR 1508.25(a)(1)), is... CFR 1508.27(b)(7)), and is not precluded by 40 CFR 1506.1 or § 1021.211 of this part concerning... pursuant to FOIA. (See also 10 CFR 1021.340.) (f) Proposed recurring activities to be undertaken during...

  4. Estimating the Proportion of Cases of Lung Cancer Legally Attributable to Smoking: A Novel Approach for Class Actions Against the Tobacco Industry

    PubMed Central

    Karp, Igor; Sylvestre, Marie-Pierre; Pintos, Javier

    2014-01-01

    Objectives. The plaintiffs’ lawyers for a class action suit, which was launched in Quebec on behalf of all patients with lung cancer whose disease was caused by cigarette smoking, asked us to estimate what proportion of lung cancer cases in Quebec, if they hypothetically could be individually evaluated, would satisfy the criterion that it is “more likely than not” that smoking caused the disease. Methods. The novel methodology we developed is based on the dose–response relationship between smoking and lung cancer, for which we use the pack-years as a measure of smoking, and the distribution of pack-years of smoking among cases. Results. We estimated that the amount of smoking required to satisfy the ”more likely than not” criterion is between 3 and 11 pack-years. More than 90% of the Quebec cases satisfied even the most conservative of these thresholds. Conclusions. More than 90% of cases of lung cancer in Quebec are legally attributable to smoking. The methodology enhances the ability to conduct class action suits against the tobacco industry. PMID:24922168

  5. Class analysis and the reorientation of class theory: the case of persisting differentials in educational attainment. 1996.

    PubMed

    Goldthorpe, John H

    2010-01-01

    In class analysis the main regularities that have been established by empirical research are not ones of long-term class formation or decomposition, as envisaged in Marxist or liberal theory, but rather ones that exhibit the powerful resistance to change of class relations and associated life-chances and patterns of social action. If these regularities are to be explained, theory needs to be correspondingly reoriented, and must abandon functionalist and teleological assumptions in favour of providing more secure micro-foundations. This argument is developed and illustrated in the course of an attempt to apply rational action theory to the explanation of persisting class differentials in educational attainment. PMID:20092500

  6. IK independent class III actions of MS-551 compared with sematilide and dofetilide during reperfusion in anaesthetized rats.

    PubMed Central

    Chen, J.; Komori, S.; Li, B.; Tamura, K.; Hashimoto, K.

    1996-01-01

    1. The antiarrhythmic and haemodynamic effects of three class III antiarrhythmic drugs, MS-551, sematilide and dofetilide, were examined in the coronary artery, ligation-reperfusion model of pentobarbitone-anaesthetized rats, a species deficient in functional cardiac IK. MS-551 is a non-selective potassium channel blocker, while both sematilide and dofetilide are selective delayed rectifier potassium (K) channel (IK) blockers. 2. Before coronary ligation, 3 and 10 mg kg-1 MS-551 decreased the heart rate by 6% (P < 0.01) and 12% (P < 0.01), and increased mean arterial pressure (MAP) by 14% (P < 0.05) and 33% (P < 0.01), respectively. Sematilide at 10 and 30 mg kg-1 also decreased the heart rate by 4% (P < 0.01) and 9% (P < 0.01), respectively, and the higher dose of 30 mg kg-1 decreased MAP by 29% (P < 0.01). Dofetilide, 1 mg kg-1, decreased the heart rate (P < 0.01), but had no significant effect on MAP. 3. The QT interval was increased by 10% (P < 0.01) and 31% (P < 0.01), when 3 and 10 mg kg-1 MS-551 were given. Sematilide and dofetilide had no effect on the QT interval. 4. Immediately after reperfusion, lethal ventricular fibrillation (VF) was induced in 80% of the saline group. MS-551 at 3 and 10 mg kg-1, reduced the incidence of lethal VF to 50% and 20% (P < 0.05). Neither dofetilide 1 mg kg-1 nor sematilide (10 and 30 mg kg-1) decreased the incidence of lethal VF (70%, 80% and 50%, respectively). None of the three drugs had any effect on the occurrence of reperfusion-induced VT or the total incidence of VF. However, 10 mg kg-1 MS-551 delayed the onset of reperfusion-induced VF (27 +/- 5 s compared with 12 +/- 2 s of the control group, P < 0.05). 5. In conclusion, in rats which are deficient in cardiac IK MS-551 prolonged the QT interval and reduced the incidence of sustained VF after reperfusion. Blockade of channels other than IK might participate in the defibrillatory effect of MS-551. Sematilide and dofetilide, which are selective IK blockers, did not

  7. Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors

    SciTech Connect

    Sanches, Mario; Duffy, Nicole M.; Talukdar, Manisha; Thevakumaran, Nero; Chiovitti, David; Canny, Marella D.; Lee, Kenneth; Kurinov, Igor; Uehling, David; Al-awar, Rima; Poda, Gennadiy; Prakesch, Michael; Wilson, Brian; Tam, Victor; Schweitzer, Colleen; Toro, Andras; Lucas, Julie L.; Vuga, Danka; Lehmann, Lynn; Durocher, Daniel; Zeng, Qingping; Patterson, John B.; Sicheri, Frank

    2014-10-24

    Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA substrates to re-establish ER homeostasis. Aromatic ring systems containing hydroxy–aldehyde moieties, termed hydroxy–aryl–aldehydes (HAA), selectively inhibit IRE1α RNase and thus represent a novel chemical series for therapeutic development. We solved crystal structures of murine IRE1α in complex with three HAA inhibitors. HAA inhibitors engage a shallow pocket at the RNase-active site through pi-stacking interactions with His910 and Phe889, an essential Schiff base with Lys907 and a hydrogen bond with Tyr892. Structure–activity studies and mutational analysis of contact residues define the optimal chemical space of inhibitors and validate the inhibitor-binding site. These studies lay the foundation for understanding both the biochemical and cellular functions of IRE1α using small molecule inhibitors and suggest new avenues for inhibitor design.

  8. 31 CFR 30.8 - Q-8: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Q-8: What actions are necessary for a... âclawbackâ provision requirement)? 30.8 Section 30.8 Money and Finance: Treasury Office of the Secretary of the Treasury TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.8 Q-8: What actions...

  9. 31 CFR 30.4 - Q-4: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Q-4: What actions are necessary for a... or manipulation of earnings)? 30.4 Section 30.4 Money and Finance: Treasury Office of the Secretary of the Treasury TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.4 Q-4: What actions...

  10. The Combined Structural and Kinetic Characterization of a Bacterial Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1 Establishes NMO Class I and II*

    PubMed Central

    Salvi, Francesca; Agniswamy, Johnson; Yuan, Hongling; Vercammen, Ken; Pelicaen, Rudy; Cornelis, Pierre; Spain, Jim C.; Weber, Irene T.; Gadda, Giovanni

    2014-01-01

    Nitronate monooxygenase (NMO) oxidizes the mitochondrial toxin propionate 3-nitronate (P3N) to malonate semialdehyde. The enzyme has been previously characterized biochemically in fungi, but no structural information is available. Based on amino acid similarity 4,985 genes are annotated in the GenBankTM as NMO. Of these, 4,424 (i.e. 89%) are bacterial genes, including several Pseudomonads that have been shown to use P3N as growth substrate. Here, we have cloned and expressed the gene pa4202 of Pseudomonas aeruginosa PAO1, purified the resulting protein, and characterized it. The enzyme is active on P3N and other alkyl nitronates, but cannot oxidize nitroalkanes. P3N is the best substrate at pH 7.5 and atmospheric oxygen with kcatapp/Kmapp of 12 × 106 m−1 s−1, kcatapp of 1300 s−1, and Kmapp of 110 μm. Anerobic reduction of the enzyme with P3N yields a flavosemiquinone, which is formed within 7.5 ms, consistent with this species being a catalytic intermediate. Absorption spectroscopy, mass spectrometry, and x-ray crystallography demonstrate a tightly, non-covalently bound FMN in the active site of the enzyme. Thus, PA4202 is the first NMO identified and characterized in bacteria. The x-ray crystal structure of the enzyme was solved at 1.44 Å, showing a TIM barrel-fold. Four motifs in common with the biochemically characterized NMO from Cyberlindnera saturnus are identified in the structure of bacterial NMO, defining Class I NMO, which includes bacterial, fungal, and two animal NMOs. Notably, the only other NMO from Neurospora crassa for which biochemical evidence is available lacks the four motifs, defining Class II NMO. PMID:25002579

  11. Establishing a framework for the Ad/abaxial regulatory network of Arabidopsis: ascertaining targets of class III homeodomain leucine zipper and KANADI regulation.

    PubMed

    Reinhart, Brenda J; Liu, Tie; Newell, Nicole R; Magnani, Enrico; Huang, Tengbo; Kerstetter, Randall; Michaels, Scott; Barton, M Kathryn

    2013-09-01

    The broadly conserved Class III homeodomain leucine zipper (HD-ZIPIII) and KANADI transcription factors have opposing and transformational effects on polarity and growth in all tissues and stages of the plant's life. To obtain a comprehensive understanding of how these factors work, we have identified transcripts that change in response to induced HD-ZIPIII or KANADI function. Additional criteria used to identify high-confidence targets among this set were presence of an adjacent HD-ZIPIII binding site, expression enriched within a subdomain of the shoot apical meristem, mutant phenotype showing defect in polar leaf and/or meristem development, physical interaction between target gene product and HD-ZIPIII protein, opposite regulation by HD-ZIPIII and KANADI, and evolutionary conservation of the regulator-target relationship. We find that HD-ZIPIII and KANADI regulate tissue-specific transcription factors involved in subsidiary developmental decisions, nearly all major hormone pathways, and new actors (such as indeterminate domain4) in the ad/abaxial regulatory network. Multiple feedback loops regulating HD-ZIPIII and KANADI are identified, as are mechanisms through which HD-ZIPIII and KANADI oppose each other. This work lays the foundation needed to understand the components, structure, and workings of the ad/abaxial regulatory network directing basic plant growth and development. PMID:24076978

  12. Establishing a Framework for the Ad/Abaxial Regulatory Network of Arabidopsis: Ascertaining Targets of Class III HOMEODOMAIN LEUCINE ZIPPER and KANADI Regulation[W

    PubMed Central

    Reinhart, Brenda J.; Liu, Tie; Newell, Nicole R.; Magnani, Enrico; Huang, Tengbo; Kerstetter, Randall; Michaels, Scott; Barton, M. Kathryn

    2013-01-01

    The broadly conserved Class III HOMEODOMAIN LEUCINE ZIPPER (HD-ZIPIII) and KANADI transcription factors have opposing and transformational effects on polarity and growth in all tissues and stages of the plant's life. To obtain a comprehensive understanding of how these factors work, we have identified transcripts that change in response to induced HD-ZIPIII or KANADI function. Additional criteria used to identify high-confidence targets among this set were presence of an adjacent HD-ZIPIII binding site, expression enriched within a subdomain of the shoot apical meristem, mutant phenotype showing defect in polar leaf and/or meristem development, physical interaction between target gene product and HD-ZIPIII protein, opposite regulation by HD-ZIPIII and KANADI, and evolutionary conservation of the regulator–target relationship. We find that HD-ZIPIII and KANADI regulate tissue-specific transcription factors involved in subsidiary developmental decisions, nearly all major hormone pathways, and new actors (such as INDETERMINATE DOMAIN4) in the ad/abaxial regulatory network. Multiple feedback loops regulating HD-ZIPIII and KANADI are identified, as are mechanisms through which HD-ZIPIII and KANADI oppose each other. This work lays the foundation needed to understand the components, structure, and workings of the ad/abaxial regulatory network directing basic plant growth and development. PMID:24076978

  13. Uptake of /sup 226/Ra by established vegetation and black cutworm larvae, Agrotis ipsilon (class Insecta: order Lepidoptera), on U mill tailings at Elliot Lake, Canada

    SciTech Connect

    Clulow, F.V.; Dave, N.K.; Lim, T.P.; Cloutier, N.R.

    1988-07-01

    Radium-226 levels in samples from an inactive U tailings site at Elliot Lake, Ontario, Canada, were: 9140 +/- 500 mBq g-1 dry weight in the substrate; 62 +/- 1 mBq g-1 dry weight in rye, Secale cereale, and less than 3.7 mBq g-1 dry weight in oats, Avena sativa, the dominant species established by revegetation of the tailings; and 117 +/- 7 mBq g-1 dry weight in washed and unwashed black cutworm larvae. Concentration ratios were: vegetation to tailings 0.001-0.007; black cutworms to vegetation 3.6 and black cutworms to tailings 0.01. The values are considered too low to be considered a hazard to herring gulls, Larus argentatus, which occasionally feed on cutworms.

  14. A method for establishing class III medical device equivalence: sodium hyaluronate (GenVisc 850) for the treatment of knee osteoarthritis

    PubMed Central

    Doros, Gheorghe; Lavin, Philip T; Daley, Michael; Miller, Larry E

    2016-01-01

    Although the concept of equivalence for drugs (generics) and biologics (biosimilars) has been readily adopted, the concept of equivalence or indistinguishable characteristics for class III medical devices has yet to be specifically addressed regarding a defined regulatory approval process in the US. In September 2015, GenVisc 850® (sodium hyaluronate), a hyaluronic acid approved for the treatment of knee osteoarthritis, was approved by the US Food and Drug Administration (FDA) based upon indistinguishable characteristics in comparison to an approved branded hyaluronic acid (Supartz®/Supartz FX™). The purpose of this paper is to review the methodology and report the main outcomes used to demonstrate clinical comparability of GenVisc 850 with Supartz/Supartz FX. The FDA approval was collectively attained using prospectively defined methods for preclinical, physical, and chemical testing, as well as noninferiority in clinical performance comparisons. Evidence from five randomized controlled studies of Supartz/Supartz FX vs saline control injections (used for Supartz approval), two randomized controlled trials of GenVisc 850 vs saline control injections, and one randomized controlled study of GenVisc 850 vs Supartz/Supartz FX provided evidence of safety for GenVisc 850. Efficacy was further assessed based on assessment of the same Supartz studies and three prospectively identified GenVisc 850 studies. A Bayesian network meta-analysis was used to demonstrate that the clinical efficacy of GenVisc 850 was noninferior to Supartz/Supartz FX and superior to saline control. Overall, safety of GenVisc 850 was similar to that of Supartz/Supartz FX and saline control injections, while efficacy of GenVisc 850 was noninferior to that of Supartz/Supartz FX and superior to saline control injections. PMID:27471412

  15. A method for establishing class III medical device equivalence: sodium hyaluronate (GenVisc 850) for the treatment of knee osteoarthritis.

    PubMed

    Doros, Gheorghe; Lavin, Philip T; Daley, Michael; Miller, Larry E

    2016-01-01

    Although the concept of equivalence for drugs (generics) and biologics (biosimilars) has been readily adopted, the concept of equivalence or indistinguishable characteristics for class III medical devices has yet to be specifically addressed regarding a defined regulatory approval process in the US. In September 2015, GenVisc 850® (sodium hyaluronate), a hyaluronic acid approved for the treatment of knee osteoarthritis, was approved by the US Food and Drug Administration (FDA) based upon indistinguishable characteristics in comparison to an approved branded hyaluronic acid (Supartz®/Supartz FX™). The purpose of this paper is to review the methodology and report the main outcomes used to demonstrate clinical comparability of GenVisc 850 with Supartz/Supartz FX. The FDA approval was collectively attained using prospectively defined methods for preclinical, physical, and chemical testing, as well as noninferiority in clinical performance comparisons. Evidence from five randomized controlled studies of Supartz/Supartz FX vs saline control injections (used for Supartz approval), two randomized controlled trials of GenVisc 850 vs saline control injections, and one randomized controlled study of GenVisc 850 vs Supartz/Supartz FX provided evidence of safety for GenVisc 850. Efficacy was further assessed based on assessment of the same Supartz studies and three prospectively identified GenVisc 850 studies. A Bayesian network meta-analysis was used to demonstrate that the clinical efficacy of GenVisc 850 was noninferior to Supartz/Supartz FX and superior to saline control. Overall, safety of GenVisc 850 was similar to that of Supartz/Supartz FX and saline control injections, while efficacy of GenVisc 850 was noninferior to that of Supartz/Supartz FX and superior to saline control injections. PMID:27471412

  16. 31 CFR 30.4 - Q-4: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... or manipulation of earnings)? 30.4 Section 30.4 Money and Finance: Treasury Office of the Secretary... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Q-4: What actions are necessary for a... excessive risk or manipulation of earnings)? (a) General rule. To comply with the standards...

  17. 31 CFR 30.4 - Q-4: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... or manipulation of earnings)? 30.4 Section 30.4 Money and Finance: Treasury Office of the Secretary... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Q-4: What actions are necessary for a... excessive risk or manipulation of earnings)? (a) General rule. To comply with the standards...

  18. 31 CFR 30.4 - Q-4: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... or manipulation of earnings)? 30.4 Section 30.4 Money and Finance: Treasury Office of the Secretary... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Q-4: What actions are necessary for a... excessive risk or manipulation of earnings)? (a) General rule. To comply with the standards...

  19. 31 CFR 30.4 - Q-4: What actions are necessary for a TARP recipient to comply with the standards established...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... or manipulation of earnings)? 30.4 Section 30.4 Money and Finance: Treasury Office of the Secretary... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Q-4: What actions are necessary for a... excessive risk or manipulation of earnings)? (a) General rule. To comply with the standards...

  20. The Protestant Establishment Revisited

    ERIC Educational Resources Information Center

    Baltzell, E. Digby

    1976-01-01

    The author's book, "The Protestant Establishment: Aristocracy and Caste in America", is highly critical of the WASP (White-Anglo-Saxon-Protestant) establishment and proposed the development and need for some sort of upper-class ruling-group. Here is a re-evaluation of his book, now thirteen years old, by the author. (Author/RK)

  1. Technology assessment and citizen action

    NASA Technical Reports Server (NTRS)

    Mottur, E. R.

    1972-01-01

    The importance of citizen participation in the assessment process is discussed, and a system for citizen assessment action is proposed. A national assessment system is outlined. Citizen participation is considered essential in the assessment process, and impediments to effective action taken by citizens are discussed. These impediments are finance, organization and motivation, and information. The establishment of citizens' assessment associations is proposed, whose functioning would be fostered and regulated by the Citizens' Assessment Administration. The organization, functions, and financing of these associations are described. The implications of citizen action are indicated as the extensive use of class action suits, the broad interpretation of associated costs of litigation, and the use of present scientific research as evidence to assert that it is reasonable to conclude that certain consequences are probable to occur in the future.

  2. 78 FR 30797 - Proposed Amendment of Class E Airspace; Point Thomson, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...This action proposes to modify the airspace at Point Thomson, AK by establishing Class E Airspace at Point Thomson Airstrip Airport, Point Thomson, AK. This will accommodate aircraft using a new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at the airport. The FAA is proposing this action to enhance the safety and management of aircraft......

  3. Developing and establishing the validity and reliability of the perceptions toward Aviation Safety Action Program (ASAP) and Line Operations Safety Audit (LOSA) questionnaires

    NASA Astrophysics Data System (ADS)

    Steckel, Richard J.

    Aviation Safety Action Program (ASAP) and Line Operations Safety Audits (LOSA) are voluntary safety reporting programs developed by the Federal Aviation Administration (FAA) to assist air carriers in discovering and fixing threats, errors and undesired aircraft states during normal flights that could result in a serious or fatal accident. These programs depend on voluntary participation of and reporting by air carrier pilots to be successful. The purpose of the study was to develop and validate a measurement scale to measure U.S. air carrier pilots' perceived benefits and/or barriers to participating in ASAP and LOSA programs. Data from these surveys could be used to make changes to or correct pilot misperceptions of these programs to improve participation and the flow of data. ASAP and LOSA a priori models were developed based on previous research in aviation and healthcare. Sixty thousand ASAP and LOSA paper surveys were sent to 60,000 current U.S. air carrier pilots selected at random from an FAA database of pilot certificates. Two thousand usable ASAP and 1,970 usable LOSA surveys were returned and analyzed using Confirmatory Factor Analysis. Analysis of the data using confirmatory actor analysis and model generation resulted in a five factor ASAP model (Ease of use, Value, Improve, Trust and Risk) and a five factor LOSA model (Value, Improve, Program Trust, Risk and Management Trust). ASAP and LOSA data were not normally distributed, so bootstrapping was used. While both final models exhibited acceptable fit with approximate fit indices, the exact fit hypothesis and the Bollen-Stine p value indicated possible model mis-specification for both ASAP and LOSA models.

  4. Loose Lug Nuts, Lobbed Beer Bottles, and Buckets of Crawdads: Reflecting on Questions of Race and Class Uncovered through Cross-Cultural Transdisciplinary Action-Research Partnerships

    ERIC Educational Resources Information Center

    Thering, Susan

    2010-01-01

    This essay is a compilation of vignettes and reflections that illustrate the author's ongoing journey from a vague detached historical awareness to a more nuanced understanding of the multiple and intersecting dimensions of race and class. The vignettes flash forward and back, recalling events that took place over years of coordinating…

  5. An e-Class in Action: Experiences with ICT-Intensive Teaching and Learning of Discrete Dynamical Models at Secondary School

    ERIC Educational Resources Information Center

    Heck, Andre; Houwing, Harm; de Beurs, Cor

    2009-01-01

    In 2007, a small team of university and secondary school teachers jointly developed and piloted an e-class for 4th and 5th grade students (age: 16-17 yrs) at both pre-university and general vocational level. The goal was to develop and try out innovative ways of teaching mathematics that would enable schools to offer optional courses for small…

  6. Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

    PubMed Central

    Basarab, Gregory S.; Kern, Gunther H.; McNulty, John; Mueller, John P.; Lawrence, Kenneth; Vishwanathan, Karthick; Alm, Richard A.; Barvian, Kevin; Doig, Peter; Galullo, Vincent; Gardner, Humphrey; Gowravaram, Madhusudhan; Huband, Michael; Kimzey, Amy; Morningstar, Marshall; Kutschke, Amy; Lahiri, Sushmita D.; Perros, Manos; Singh, Renu; Schuck, Virna J. A.; Tommasi, Ruben; Walkup, Grant; Newman, Joseph V.

    2015-01-01

    With the diminishing effectiveness of current antibacterial therapies, it is critically important to discover agents that operate by a mechanism that circumvents existing resistance. ETX0914, the first of a new class of antibacterial agent targeted for the treatment of gonorrhea, operates by a novel mode-of-inhibition against bacterial type II topoisomerases. Incorporating an oxazolidinone on the scaffold mitigated toxicological issues often seen with topoisomerase inhibitors. Organisms resistant to other topoisomerase inhibitors were not cross-resistant with ETX0914 nor were spontaneous resistant mutants to ETX0914 cross-resistant with other topoisomerase inhibitor classes, including the widely used fluoroquinolone class. Preclinical evaluation of ETX0914 pharmacokinetics and pharmacodynamics showed distribution into vascular tissues and efficacy in a murine Staphylococcus aureus infection model that served as a surrogate for predicting efficacious exposures for the treatment of Neisseria gonorrhoeae infections. A wide safety margin to the efficacious exposure in toxicological evaluations supported progression to Phase 1. Dosing ETX0914 in human volunteers showed sufficient exposure and minimal adverse effects to expect a highly efficacious anti-gonorrhea therapy. PMID:26168713

  7. Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.

    PubMed

    Basarab, Gregory S; Kern, Gunther H; McNulty, John; Mueller, John P; Lawrence, Kenneth; Vishwanathan, Karthick; Alm, Richard A; Barvian, Kevin; Doig, Peter; Galullo, Vincent; Gardner, Humphrey; Gowravaram, Madhusudhan; Huband, Michael; Kimzey, Amy; Morningstar, Marshall; Kutschke, Amy; Lahiri, Sushmita D; Perros, Manos; Singh, Renu; Schuck, Virna J A; Tommasi, Ruben; Walkup, Grant; Newman, Joseph V

    2015-01-01

    With the diminishing effectiveness of current antibacterial therapies, it is critically important to discover agents that operate by a mechanism that circumvents existing resistance. ETX0914, the first of a new class of antibacterial agent targeted for the treatment of gonorrhea, operates by a novel mode-of-inhibition against bacterial type II topoisomerases. Incorporating an oxazolidinone on the scaffold mitigated toxicological issues often seen with topoisomerase inhibitors. Organisms resistant to other topoisomerase inhibitors were not cross-resistant with ETX0914 nor were spontaneous resistant mutants to ETX0914 cross-resistant with other topoisomerase inhibitor classes, including the widely used fluoroquinolone class. Preclinical evaluation of ETX0914 pharmacokinetics and pharmacodynamics showed distribution into vascular tissues and efficacy in a murine Staphylococcus aureus infection model that served as a surrogate for predicting efficacious exposures for the treatment of Neisseria gonorrhoeae infections. A wide safety margin to the efficacious exposure in toxicological evaluations supported progression to Phase 1. Dosing ETX0914 in human volunteers showed sufficient exposure and minimal adverse effects to expect a highly efficacious anti-gonorrhea therapy. PMID:26168713

  8. Action Recommendation for Cyber Resilience

    SciTech Connect

    Choudhury, Sutanay; Rodriguez, Luke R.; Curtis, Darren S.; Oler, Kiri J.; Nordquist, Peter L.; Chen, Pin-Yu; Ray, Indrajit

    2015-09-01

    This paper presents an unifying graph-based model for representing the infrastructure, behavior and missions of an enterprise. We describe how the model can be used to achieve resiliency against a wide class of failures and attacks. We introduce an algorithm for recommending resilience establishing actions based on dynamic updates to the models. Without loss of generality, we show the effectiveness of the algorithm for preserving latency based quality of service (QoS). Our models and the recommendation algorithms are implemented in a software framework that we seek to release as an open source framework for simulating resilient cyber systems.

  9. "Racializing" Class

    ERIC Educational Resources Information Center

    Hatt-Echeverria, Beth; Urrieta, Luis, Jr.

    2003-01-01

    In an effort to explore how racial and class oppressions intersect, the authors use their autobiographical narratives to depict cultural and experiential continuity and discontinuity in growing up white working class versus Chicano working class. They specifically focus on "racializing class" due to the ways class is often used as a copout by…

  10. Effect of a supportive-educative program in the math class for stress, anxiety, and depression in female students in the third level of junior high school: An action research

    PubMed Central

    Emamjomeh, Seyedeh Mahtab; Bahrami, Masoud

    2015-01-01

    Background and Aim: Students in junior high school, particularly in the third level, are prone to a variety of stressors. This in turn might lead to stress, anxiety, depression, and other health-related problems. There are a very limited number of action research studies to identify the effect of stress management techniques among students. Therefore, a study was conducted to assess the effect of a program used in the math class to decrease the student's level of stress, anxiety, and depression. Material and Methods: This was an action research study, which was conducted in region three of the Education and Training Office of Isfahan, in the year 2012. Fifty-one students in a junior high school were selected and underwent a comprehensive stress management program. This program was prepared in collaboration with the students, their parents, teachers, and managers of the school, and was implemented approximately during a four-month period. The student's stress, anxiety, and depression were measured before and after the program using the DASS-21 questionnaire. Findings: The t-test identified that the mean scores of stress, anxiety, and depression after the intervention were significantly lower than the corresponding scores before the program. One-way analysis of variance (ANOVA) also showed that the students from the veterans (Janbaz) families had higher levels of stress compared to their classmates, who belonged to the non-veteran families (P< 0.05). Results: Education and implementation of stress management techniques including cognitive and behavioral interventions along with active and collaborative methods of learning in the math class might be useful both inside and outside the class, for better management of stress and other health-related problems of students. PMID:25767821

  11. Establishing operations

    PubMed Central

    Michael, Jack

    1993-01-01

    The first two books on behavior analysis (Skinner, 1938; Keller & Schoenfeld, 1950) had chapter-length coverage of motivation. The next generation of texts also had chapters on the topic, but by the late 1960s it was no longer being given much treatment in the behavior-analytic literature. The present failure to deal with the topic leaves a gap in our understanding of operant functional relations. A partial solution is to reintroduce the concept of the establishing operation, defined as an environmental event, operation, or stimulus condition that affects an organism by momentarily altering (a) the reinforcing effectiveness of other events and (b) the frequency of occurrence of that part of the organism's repertoire relevant to those events as consequences. Discriminative and motivative variables can be distinguished as follows: The former are related to the differential availability of an effective form of reinforcement given a particular type of behavior; the latter are related to the differential reinforcing effectiveness of environmental events. An important distinction can also be made between unconditioned establishing operations (UEOs), such as food deprivation and painful stimulation, and conditioned establishing operations (CEOs) that depend on the learning history of the organism. One type of CEO is a stimulus that has simply been paired with a UEO and as a result may take on some of the motivative properties of that UEO. The warning stimulus in avoidance procedures is another important type of CEO referred to as reflexive because it establishes its own termination as a form of reinforcement and evokes the behavior that has accomplished such termination. Another CEO is closely related to the concept of conditional conditioned reinforcement and is referred to as a transitive CEO, because it establishes some other stimulus as a form of effective reinforcement and evokes the behavior that has produced that other stimulus. The multiple control of human

  12. 78 FR 65208 - Modification of Class D and E Airspace; Kenai, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ...This action modifies Class D and E airspace at Kenai Municipal Airport, Kenai, AK. Controlled airspace is necessary to accommodate aircraft using the new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at the airport. A minor adjustment is made to the geographic coordinates of the airport. Additionally, language establishing dates and times of use......

  13. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404 Class deviations. Class deviations affect more than one contracting action. Where deviations from the FAR or...

  14. Class Size.

    ERIC Educational Resources Information Center

    Underwood, Siobhan; Lumsden, Linda S.

    1994-01-01

    The items featured in this annotated bibliography touch on several aspects of the multifaceted class-size debate. Allen Odden reviews the literature and contends that class-size reduction should be used "sparingly and strategically." C. M. Achilles and colleagues examines two different class-size situations and find student test performance in the…

  15. Class Size.

    ERIC Educational Resources Information Center

    Johnston, Holly R.

    Exploring the class-size issue, this paper focuses on the primary grades and asks questions such as "does a reduction in class size promote an increase in academic achievement?" and "how substantial does the reduction in numbers have to be in order for a significant increase to occur?" The paper surveys debates on class size and the social factors…

  16. Class Matters

    ERIC Educational Resources Information Center

    Valdata, Patricia

    2005-01-01

    Ever since George Washington opted for the title of president rather than king, Americans have been uncomfortable with the idea of class distinctions. This article presents an interview with Dr. Janet Galligani Casey regarding the idea of class distinctions. Galligani Casey, who grew up in a working-class neighborhood in Somerville, Massachusetts,…

  17. 45 CFR 1225.19 - Corrective action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Corrective action. 1225.19 Section 1225.19 Public... Corrective action. (a) When discrimination is found, Peace Corps or ACTION must take appropriate action to... corrective action to the agent and other class members in accordance with § 1225.10 of this part. (b)...

  18. 48 CFR 1401.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... THE INTERIOR ACQUISITION REGULATION SYSTEM Deviations from the FAR and DIAR 1401.404 Class deviations. (a) The Director, PAM, is authorized to approve class deviations of FAR or DIAR provisions which... actions which will be affected. (c) For a FAR class deviation the Director, PAM, shall consult with...

  19. 48 CFR 501.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES ADMINISTRATION ACQUISITION REGULATION SYSTEM Deviations From the FAR and GSAR 501.404 Class... an individual contract action. (1) A class deviation to the FAR must be forwarded by the cognizant HCA to GSA's SPE for approval. Prior to approving a class deviation to the FAR, the SPE will...

  20. 76 FR 51257 - First-Class Package Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... 111 First-Class Package Service AGENCY: Postal Service\\TM\\. ACTION: Final rule. SUMMARY: The Postal... First-Class Package Service, which will replace and remove First-Class Mail commercial base and... First-Class Package Service. First-Class Package Service parcels will receive the same service as...

  1. Anticancer Properties of Distinct Antimalarial Drug Classes

    PubMed Central

    Hooft van Huijsduijnen, Rob; Guy, R. Kiplin; Chibale, Kelly; Haynes, Richard K.; Peitz, Ingmar; Kelter, Gerhard; Phillips, Margaret A.; Vennerstrom, Jonathan L.; Yuthavong, Yongyuth; Wells, Timothy N. C.

    2013-01-01

    We have tested five distinct classes of established and experimental antimalarial drugs for their anticancer potential, using a panel of 91 human cancer lines. Three classes of drugs: artemisinins, synthetic peroxides and DHFR (dihydrofolate reductase) inhibitors effected potent inhibition of proliferation with IC50s in the nM- low µM range, whereas a DHODH (dihydroorotate dehydrogenase) and a putative kinase inhibitor displayed no activity. Furthermore, significant synergies were identified with erlotinib, imatinib, cisplatin, dasatinib and vincristine. Cluster analysis of the antimalarials based on their differential inhibition of the various cancer lines clearly segregated the synthetic peroxides OZ277 and OZ439 from the artemisinin cluster that included artesunate, dihydroartemisinin and artemisone, and from the DHFR inhibitors pyrimethamine and P218 (a parasite DHFR inhibitor), emphasizing their shared mode of action. In order to further understand the basis of the selectivity of these compounds against different cancers, microarray-based gene expression data for 85 of the used cell lines were generated. For each compound, distinct sets of genes were identified whose expression significantly correlated with compound sensitivity. Several of the antimalarials tested in this study have well-established and excellent safety profiles with a plasma exposure, when conservatively used in malaria, that is well above the IC50s that we identified in this study. Given their unique mode of action and potential for unique synergies with established anticancer drugs, our results provide a strong basis to further explore the potential application of these compounds in cancer in pre-clinical or and clinical settings. PMID:24391728

  2. Improving Teaching with Collaborative Action Research: An ASCD Action Tool

    ERIC Educational Resources Information Center

    Cunningham, Diane

    2011-01-01

    Once you've established a professional learning community (PLC), you need to get this ASCD (Association for Supervision and Curriculum Development) action tool to ensure that your PLC stays focused on addressing teaching methods and student learning problems. This ASCD action tool explains how your PLC can use collaborative action research to…

  3. Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship.

    PubMed

    Manda, Sudhakar; Sharma, Sadhana; Wani, Abubakar; Joshi, Prashant; Kumar, Vikas; Guru, Santosh K; Bharate, Sonali S; Bhushan, Shashi; Vishwakarma, Ram A; Kumar, Ajay; Bharate, Sandip B

    2016-01-01

    The screening of IIIM natural products repository for P-gp modulatory activity in P-gp over-expressing human adenocarcinoma LS-180 cells led to the identification of 7 natural products viz. withaferin, podophyllotoxin, 3-demethylcolchicine, agnuside, reserpine, seseberecine and fascaplysin as P-gp inducers. Fascaplysin (6a), a marine-derived bis-indole alkaloid, was the most potent among all of them, showing induction of P-gp with EC50 value of 25 nM. P-gp induction is one of the recently targeted strategy to increase amyloid-β clearance from Alzheimer brains. Thus, we pursued a medicinal chemistry of fascaplysin to establish its structure-activity relationship for P-gp induction activity. Four series of analogs viz. substituted quaternary fascaplysin analogs, D-ring opened quaternary analogs, D-ring opened non-quaternary analogs, and β-carbolinium analogs were synthesized and screened for P-gp induction activity. Among the total of 48 analogs screened, only quaternary nitrogen containing analogs 6a-g and 10a, 10h-l displayed promising P-gp induction activity; whereas non-planar non-quaternary analogs 9a-m, 13a-n, 15a-h were devoid of this activity. The P-gp induction activity of best compounds was then confirmed by western-blot analysis, which indicated that fascaplysin (6a) along with 4,5-difluoro analog of fascaplysin 6f and D-ring opened analog 10j displayed 4-8 fold increase in P-gp expression in LS-180 cells at 1 μM. Additionally, compounds 6a and 6f also showed inhibition of acetylcholinestease (AChE), an enzyme responsible for neuronal loss in Alzheimer's disease. Thus, fascaplysin and its analogs showing promising P-gp induction along with AChE inhibition at 1 μM, with good safety window (LS-180: IC50 > 10 μM, hGF: 4 μM), clearly indicates their promise for development as an anti-Alzheimer agent. PMID:26560048

  4. 78 FR 11996 - Proposed Modification of Class D and Class E Airspace; Pueblo, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ...This action proposes to modify Class D airspace and the Class E airspace areas at Pueblo Memorial Airport, Pueblo, CO. Controlled airspace is necessary to accommodate aircraft using VHF Omni- Directional Radio Range/Distance Measuring Equipment (VOR/DME) standard instrument approach procedures at Pueblo Memorial Airport. The FAA is proposing this action to enhance the safety and management of......

  5. Project CLASS.

    ERIC Educational Resources Information Center

    McBain, Susan L.; And Others

    Project CLASS (Competency-Based Live-Ability Skills) uses a series of 60 modules to teach life survival skills to adults with low-level reading ability--especially Adult Basic Education/English as a Second Language students. Two versions of the modules have been developed: one for use with teacher-directed instruction and another for independent…

  6. Class Trash.

    ERIC Educational Resources Information Center

    Chemecology, 1992

    1992-01-01

    Presents a classroom activity in which students calculate the amount and types of trash thrown out by their class at school to investigate how much trash is generated, where it goes, and speculate about alternatives. Students need to be familiar with the concepts of weight, volume, and numbers. (MCO)

  7. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor.

    PubMed

    Newman-Tancredi, Adrian; Cussac, Didier; Audinot, Valérie; Nicolas, Jean-Paul; De Ceuninck, Frédéric; Boutin, Jean-A; Millan, Mark J

    2002-11-01

    The accompanying multivariate analysis of the binding profiles of antiparkinson agents revealed contrasting patterns of affinities at diverse classes of monoaminergic receptor. Herein, we characterized efficacies at human (h)D(2SHORT(S)), hD(2LONG(L)), hD(3), and hD(4.4) receptors and at halpha(2A)-, halpha(2B)-, halpha(2C)-, and halpha(1A)-adrenoceptors (ARs). As determined by guanosine 5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPgammaS) binding, no ligand displayed "full" efficacy relative to dopamine (100%) at all "D(2)-like" sites. However, at hD(2S) receptors quinpirole, pramipexole, ropinirole, quinerolane, pergolide, and cabergoline were as efficacious as dopamine (E(max)100%); TL99, talipexole, and apomorphine were highly efficacious (79-92%); piribedil, lisuride, bromocriptine, and terguride showed intermediate efficacy (40-55%); and roxindole displayed low efficacy (11%). For all drugs, efficacies were lower at hD(2L) receptors, with terguride and roxindole acting as antagonists. At hD(3) receptors, efficacies ranged from 33% (roxindole) to 94% (TL99), whereas, for hD(4) receptors, highest efficacies (approximately 70%) were seen for quinerolane, quinpirole, and TL99, whereas piribedil and terguride behaved as antagonists and bromocriptine was inactive. Although efficacies at hD(2S) versus hD(2L) sites were highly correlated (r = 0.79), they correlated only modestly to hD(3)/hD(4) sites (r = 0.44-0.59). In [(35)S]GTPgammaS studies of halpha(2A)-ARs, TL99 (108%), pramipexole (52%), talipexole (51%), pergolide (31%), apomorphine (16%), and quinerolane (11%) were agonists and ropinirole and roxindole were inactive, whereas piribedil and other agents were antagonists. Similar findings were obtained at halpha(2B)- and halpha(2C)-ARs. Using [(3)H]phosphatidylinositol depletion, roxindole, bromocriptine, lisuride, and terguride displayed potent antagonist properties at halpha(1A)-ARs. In conclusion, antiparkinson agents display diverse agonist and antagonist

  8. 77 FR 32896 - Modification of Class E Airspace; Billings, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Billings, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E... received. Class E airspace designations are published in paragraph 6005, of FAA Order 7400.9V dated...

  9. 77 FR 10649 - Modification of Class E Airspace; Douglas, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... Administration 14 CFR Part 71 Modification of Class E Airspace; Douglas, AZ AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Bisbee Douglas... typographical error in the legal description for the Class E 700 foot airspace. This improves the safety...

  10. 76 FR 35967 - Amendment of Class E Airspace; Bozeman, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Bozeman, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... geographic coordinates for the Class D and E airspace areas, and updates the airport name. DATES:...

  11. Neural Correlates of Human Action Observation in Hearing and Deaf Subjects

    PubMed Central

    Corina, David; Chiu, Yi-Shiuan; Knapp, Heather; Greenwald, Ralf; Jose-Robertson, Lucia San; Braun, Allen

    2007-01-01

    Accumulating evidence has suggested the existence of a human action recognition system involving inferior frontal, parietal, and superior temporal regions that may participate in both the perception and execution of actions. However, little is known about the specificity of this system in response to different forms of human action. Here we present data from PET neuroimaging studies from passive viewing of three distinct action types, intransitive self-oriented actions (e.g., stretching, rubbing one’s eyes, etc.), transitive object-oriented actions (e.g., opening a door, lifting a cup to the lips to drink), and the abstract, symbolic actions–signs used in American Sign Language. Our results show that these different classes of human actions engage a frontal/parietal/STS human action recognition system in a highly similar fashion. However, the results indicate that this neural consistency across motion classes is true primarily for hearing subjects. Data from deaf signers shows a non-uniform response to different classes of human actions. As expected, deaf signers engaged left-hemisphere perisylvian language areas during the perception of signed language signs. Surprisingly, these subjects did not engage the expected frontal/parietal/STS circuitry during passive viewing of non-linguistic actions, but rather reliably activated middle-occipital temporal-ventral regions which are known to participate in the detection of human bodies, faces, and movements. Comparisons with data from hearing subjects establish statistically significant contributions of middle-occipital temporal-ventral during the processing of non-linguistic actions in deaf signers. These results suggest that during human motion processing, deaf individuals may engage specialized neural systems that allow for rapid, online differentiation of meaningful linguistic actions from non-linguistic human movements. PMID:17459349

  12. 75 FR 30295 - Amendment of Class E Airspace; Hoquiam, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ...This action will amend existing Class E airspace at Hoquiam, WA. Controlled Class E surface airspace will be continuous at Bowerman Airport, Hoquiam, WA. The FAA is taking this action to enhance the safety and management of aircraft operations at the airport. This action also will correct the airport...

  13. Choosing Actions

    PubMed Central

    Rosenbaum, David A.; Chapman, Kate M.; Coelho, Chase J.; Gong, Lanyun; Studenka, Breanna E.

    2013-01-01

    Actions that are chosen have properties that distinguish them from actions that are not. Of the nearly infinite possible actions that can achieve any given task, many of the unchosen actions are irrelevant, incorrect, or inappropriate. Others are relevant, correct, or appropriate but are disfavored for other reasons. Our research focuses on the question of what distinguishes actions that are chosen from actions that are possible but are not. We review studies that use simple preference methods to identify factors that contribute to action choices, especially for object-manipulation tasks. We can determine which factors are especially important through simple behavioral experiments. PMID:23761769

  14. Intentional Action and Action Slips.

    ERIC Educational Resources Information Center

    Heckhausen, Heinz; Beckmann, Jurgen

    1990-01-01

    An explanation of action slips is offered that examines controlled actions in the context of an intentional behavior theory. Actions are considered guided by mentally represented intentions, subdivided into goal intentions and contingent instrumental intentions. Action slips are categorized according to problem areas in the enactment of goal…

  15. Class distinction

    NASA Astrophysics Data System (ADS)

    White, M. Catherine

    Typical 101 courses discourage many students from pursuing higher level science and math courses. Introductory classes in science and math serve largely as a filter, screening out all but the most promising students, and leaving the majority of college graduates—including most prospective teachers—with little understanding of how science works, according to a study conducted for the National Science Foundation. Because few teachers, particularly at the elementary level, experience any collegiate science teaching that stresses skills of inquiry and investigation, they simply never learn to use those methods in their teaching, the report states.

  16. 76 FR 64235 - Establishment of Class E Airspace; Nahunta, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ..., GA (76 FR 45478) Docket No. FAA-2011-0727. Subsequent to publication, the FAA found a typographical... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  17. 78 FR 76054 - Establishment of Class E Airspace; Chatom, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-16

    ... Chatom, AL (78 FR 54412) Docket No. FAA-2012-1186. Interested parties were invited to participate in this... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  18. 78 FR 52085 - Establishment of Class E Airspace; Stockton, KS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... the Stockton, KS, area, creating controlled airspace at Rooks County Regional Airport (78 FR 25229... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  19. 78 FR 67297 - Establishment of Class E Airspace; Curtis, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ...., area, creating additional controlled airspace at Curtis Municipal Airport (78 FR 48838) Docket No. FAA...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  20. 78 FR 58158 - Establishment of Class E Airspace; Wasatch, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Register a notice of proposed rulemaking (NPRM) to amend controlled airspace at Wasatch, UT (78 FR... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  1. 77 FR 75836 - Establishment of Class E Airspace; Walsenburg, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... Airfield, Walsenburg, CO (77 FR 55776). Interested parties were invited to participate in this rulemaking... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  2. 75 FR 32651 - Establishment of Class E Airspace; Quitman, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... direct final rule with a request for comments in the Federal Register on April 1, 2010 (75 FR 16333... May 27, 2010. Barry A. Knight, Acting Manager, Operations Support Group Eastern Service Center,...

  3. 78 FR 48300 - Establishment of Class E Airspace; Mahnomen, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... the Mahnomen, MN, area, creating controlled airspace at Mahnomen County Airport (78 FR 25233) Docket...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  4. 75 FR 51175 - Establishment of Class E Airspace; Perryville, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... additional controlled airspace at Perryville Municipal Airport (75 FR 23636) Docket No. FAA-2010-0403... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation...

  5. 78 FR 18801 - Establishment of Class E Airspace; Beeville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Airport, Beeville, TX (77 FR 71365) Docket No. FAA- 2012-0821. Interested parties were invited to... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...

  6. 78 FR 48302 - Establishment of Class E Airspace; Wagner, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ..., area, creating controlled airspace at Wagner Municipal Airport (78 FR 31430) Docket No. FAA-2013-0004... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  7. 75 FR 68416 - Establishment of Class E Airspace; Berryville, AR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71..., creating controlled airspace at Carroll County Airport (75 FR 53876) Docket No. FAA-2010-0690. Interested... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  8. 78 FR 48301 - Establishment of Class E Airspace; Walker, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ..., area, creating controlled airspace at Walker Municipal Airport (78 FR 25234) Docket No. FAA-2013-0266... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  9. 78 FR 18802 - Establishment of Class E Airspace; Tecumseh, NE

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ..., area, creating additional controlled airspace at Tecumseh Municipal Airport (77 FR 71368) Docket No... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  10. 75 FR 40719 - Establishment of Class E Airspace; Kemmerer, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Federal Register a notice of proposed rulemaking to amend controlled airspace at Kemmerer, WY (75 FR 11477... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  11. 75 FR 39148 - Establishment of Class E Airspace; Lucin, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ..., UT (75 FR 14383). Interested parties were invited to participate in this rulemaking effort by... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  12. 76 FR 75449 - Establishment of Class E Airspace; Stuart, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... controlled airspace at the City of Stuart Helistop (76 FR 53360) Docket No. FAA-2011-0831. Interested parties... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  13. 75 FR 41984 - Establishment of Class E Airspace; Paynesville, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959... controlled airspace at Paynesville Municipal Airport (75 FR 22044) Docket No. FAA-2010-0399. Interested... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  14. 75 FR 8484 - Establishment of Class E Airspace; Langdon, ND

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... controlled airspace at Robertson Field Airport (74 FR 63684) Docket No. FAA-2009-0535. Interested parties... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...

  15. 78 FR 72008 - Establishment of Class E Airspace; Aliceville, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Aliceville, AL(78 FR 52111) Docket No. FAA-2013-0431. Interested parties were invited to participate in this... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  16. 78 FR 52425 - Establishment of Class E Airspace; Umatilla, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... Umatilla, FL (78 FR 33265) Docket No. FAA-2013-0002. Interested parties were invited to participate in this... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation...

  17. 78 FR 8962 - Establishment of Class E Airspace; Kasigluk, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ... rulemaking to modify controlled airspace at Kasigluk, AK (77 FR 60660). Interested parties were invited to... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  18. 75 FR 41985 - Establishment of Class E Airspace; Syracuse, KS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... controlled airspace at Syracuse-Hamilton County Municipal Airport (75 FR 22045) Docket No. FAA-2010-0400... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565,...

  19. 75 FR 37293 - Establishment of Class E Airspace; Hamilton, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... additional controlled airspace at Hamilton Municipal Airport (75 FR 20794) Docket No. FAA-2009-0190... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR,...

  20. 78 FR 67024 - Establishment of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... airspace at the Glasgow VOR/DME navigation aid, Glasgow, MT (78 FR 59807, September 30, 2013). The FAA... Federal Register of September 30, 2013 (78 FR 59807), Airspace Docket No. 13- ANM-17, FR Doc. 2013-23669... airspace at the Glasgow VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME)...

  1. 77 FR 45241 - Establishment of Class E Airspace; Apopka, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... Apopka, FL ] (77 FR 30439) Docket No. FAA-2012-0249. Interested parties were invited to participate in... rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation...

  2. 77 FR 45240 - Establishment of Class E Airspace; Quakertown, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... Airspace at Quakertown, PA, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS... Quakertown, PA (77 FR 30438) Docket No. FAA-2012-0386. Interested parties were invited to participate in this... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  3. 77 FR 19076 - Establishment of Class E Airspace; Marion, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... Airspace at Marion, AL, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS... Marion, AL (77 FR 771) Docket No. FAA-2011-0590. Interested parties were invited to participate in this... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  4. 76 FR 1999 - Establishment of Class E Airspace; Panguitch, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... E airspace at Panguitch, UT, to accommodate aircraft using a new Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures at Panguitch Municipal Airport. This will... Panguitch, UT (75 FR 36585). The FAA agreed with a comment received to also expand controlled airspace...

  5. 77 FR 16669 - Establishment of Class E Airspace; Bellefonte, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... airspace at Bellefonte, PA, to accommodate new Area Navigation (RNAV) Global Positioning System (GPS... surface at Bellefonte, PA (76 FR 79564). Interested parties were invited to participate in this rulemaking... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) ] does not warrant preparation of...

  6. 76 FR 14801 - Establishment of Class E Airspace; Colebrook, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... Airspace at Colebrook, NH, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS..., NH (75 FR 81516). Interested parties were invited to participate in this rulemaking effort by... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of...

  7. 77 FR 1012 - Establishment of Class E Airspace; Inverness, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... Airspace at Inverness, FL, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS... the controlled airspace required to accommodate the new Area Navigation (RNAV) Global Positioning..., FL (76 FR 66871) Docket No. FAA-2011-0540. Interested parties were invited to participate in...

  8. 78 FR 72010 - Establishment of Class E Airspace; Magee, MS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Airspace at Magee, MS, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS) special..., MS, (78 FR 48080) Docket No. FAA-2013-0430. Interested parties were invited to participate in this... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  9. 78 FR 34557 - Establishment of Class E Airspace; Sanibel, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... Airspace at Sanibel, FL, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS... Sanibel, FL (78 FR 14473). Interested parties were invited to participate in this rulemaking effort by... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  10. 78 FR 32553 - Establishment of Class E Airspace; Boothbay, ME

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... Airspace at Boothbay, ME, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS... Boothbay, ME (78 FR 18929). Interested parties were invited to participate in this rulemaking effort by... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  11. 78 FR 59622 - Establishment of Class E Airspace; Akutan, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at..., Akutan, AK (78 FR 45477). Interested parties were invited to participate in this rulemaking effort by... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  12. 75 FR 41772 - Establishment of Class E Airspace; Colebrook, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... new Area Navigation (RNAV) Global Positioning System (GPS) Special Standard Instrument Approach...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February... to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3...

  13. 76 FR 52230 - Establishment of Class E Airspace; Forest, VA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Airspace at Forest, VA, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS..., VA (76 FR 34196) Docket No. FAA-2011-0378. Interested parties were invited to participate in this... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory...

  14. 75 FR 65581 - Establishment of Class E Airspace; Colebrook, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-26

    ... (75 FR 41772), is hereby withdrawn. Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Issued in College Park, Georgia, on October 15, 2010. Mark D... Upper Valley Connecticut Hospital (74 FR 41772) Docket No.-2010-0322. After publication, the FAA...

  15. 77 FR 29875 - Establishment of Class E Airspace; Houston, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ..., area, creating controlled airspace at Houston Memorial Airport (77 FR 4711) Docket No. FAA-2011-0903...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  16. 78 FR 41290 - Establishment of Class E Airspace; Sanibel, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... Sanibel Island Heliport, Sanibel, FL. (78 FR 34557). After publication, the FAA found typographical errors... Sanibel Island Heliport, Sanibel, FL, as published in the Federal Register of June 10, 2013 (78 FR 34557), FR Doc. 2013-13107, is corrected to read: * * * * * ASO FL E5 Sanibel, FL Sanibel Island Heliport,...

  17. 77 FR 29874 - Establishment of Class E Airspace; Freer, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ..., creating additional controlled airspace at Seven C's Ranch Airport (77 FR 4700) Docket No. FAA-2011-0904... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  18. Environmental Action.

    ERIC Educational Resources Information Center

    Lott, Jesse; Allen, Rodney F.

    This booklet, a general guide to citizen eco-action, discusses a plan of action on community environmental problems. It offers factors to be considered in any community eco-action situation, but it is not a rigid set of rules. An overview identifies seven key ideas of environmental issues, including the universal participation of all humans in the…

  19. Technical Basis for Also Using Health-Risk Assessment to Establish Contaminant Boundaries for Corrective Action Units (CAUs) of the Underground Test Area (UGTA) at the Nevada Test Site (NTS)

    SciTech Connect

    Daniels, J I; Tompson, A F

    2003-12-29

    This technical basis document serves two purposes. First, it provides a detailed discussion of the rationale and procedures suitable for deriving a risk-based contaminant boundary that will protect public health unambiguously, along with examples that are intended as illustrative only to facilitate understanding. Second, it explains the benefits of using such information as the framework for fostering risk communication to educate, inform, and enlighten, and importantly, to fully disclose the goals and structure of contaminant boundaries. To determine a contaminant boundary within a CAU, standards or criteria must be adopted that establish whether groundwater is safe or unsafe for public (and worker) use. For purposes of this discussion, drinking water consumption is considered the pathway of exposure. However, in practice, a realistic land-use scenario must be described and agreed upon before a prospective, realistic risk-based calculation is performed. Otherwise, it will not be clear whether consumption of drinking water is a even appropriate. For example, the future land use that is defined may not even permit access to the contaminated water (e.g., denial of use by law and stewardship; or a lack of accessibility), and in that situation there would be no exposure and no potential health consequences. Taking into consideration that consumption of the groundwater is feasible, the groundwater is deemed unsafe if it contains radionuclide contamination that exceeds the criteria that the United States Environmental Protection Agency (EPA) considers in establishing regulatory standards for drinking water contaminants, including radionuclides generally (i.e., a target range for lifetime excess-cancer risk that is not to exceed 10{sup -4} [1/10,000] and ideally is less than 10{sup -6} [1/1,000,000]) (see EPA, 2000a). Thus, the maximum contaminant levels (MCLs) for substances in drinking water are considered to be health-protective and generally are derived on the basis

  20. 5 CFR 1201.27 - Class appeals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Class appeals. 1201.27 Section 1201.27 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES PRACTICES AND PROCEDURES Procedures for Appellate Cases Appeal of Agency Action; Pleadings § 1201.27 Class appeals. (a) Appeal. One...

  1. 5 CFR 1201.27 - Class appeals.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Class appeals. 1201.27 Section 1201.27 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES PRACTICES AND PROCEDURES Procedures for Appellate Cases Appeal of Agency Action; Pleadings § 1201.27 Class appeals. (a) Appeal. One...

  2. 5 CFR 1201.27 - Class appeals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Class appeals. 1201.27 Section 1201.27 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES PRACTICES AND PROCEDURES Procedures for Appellate Cases Appeal of Agency Action; Pleadings § 1201.27 Class appeals. (a) Appeal. One...

  3. The modular class of a Dirac map

    NASA Astrophysics Data System (ADS)

    Caseiro, Raquel

    2016-06-01

    In this paper we study the modular classes of Dirac manifolds and of Dirac maps, and we discuss their basic properties. We apply these results to explain the relationship between the modular classes of the various structures involved in the reduction of a Poisson manifold under the action of a Poisson-Lie group.

  4. Affirmative Action Plan.

    ERIC Educational Resources Information Center

    Triton Coll., River Grove, IL.

    In order to develop an affirmative action plan at Triton College, the college President appointed a committee made up of nine representatives from the various college constituencies, the majority of which were women and minorities, to determine the objectives to be achieved and how to implement them, and to establish appropriate review procedures.…

  5. Literacy Education Action.

    ERIC Educational Resources Information Center

    Clymer, Carol

    The Literacy Education Action (LEA) program was established in the fall of 1985 under the initiative of the president of the El Paso Community College (Texas). During 1985 and 1986, LEA concentrated on developing its own literacy tutoring program, including recruiting and training volunteers and community members with reading skills below the…

  6. To amend a provision of the Securities Act of 1933 directing the Securities and Exchange Commission to add a particular class of securities to those exempted under such Act to provide a deadline for such action.

    THOMAS, 113th Congress

    Rep. McHenry, Patrick T. [R-NC-10

    2013-02-14

    05/16/2013 Received in the Senate and Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  7. Action Learning.

    ERIC Educational Resources Information Center

    1996

    These four papers were presented at a symposium on action learning moderated by Lex Dilworth at the 1996 conference of the Academy of Human Resource Development. "Developing an Infrastructure for Individual and Organizational Change: Transfer of Learning from an Action Reflection Learning (ARL) Program" (ARL Inquiry) reports findings from a study…

  8. Technology assessment and citizen action

    NASA Technical Reports Server (NTRS)

    Mottur, E. R.

    1975-01-01

    Citizen participation in the nation's total social, political, economic decisionmaking processes was studied. Impediments are discussed which prevent citizens from taking effective assessment action; these include finance, organization and motivation, and information. The proposal for establishing citizens assessment associations is considered along with implications of citizen assessment action.

  9. Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels.

    PubMed

    Schmidt, Constanze; Wiedmann, Felix; Schweizer, Patrick A; Becker, Rüdiger; Katus, Hugo A; Thomas, Dierk

    2013-12-01

    Class IC antiarrhythmic drugs are commonly used for rhythm control in atrial fibrillation. In addition, class I drugs are administered to suppress ventricular tachyarrhythmia in selected cases. The multichannel blocking profile of class I compounds includes reduction of cardiac potassium currents in addition to their primary mechanism of action, sodium channel inhibition. Blockade of two-pore-domain potassium (K2P) channels in the heart causes action potential prolongation and may provide antiarrhythmic action in atrial fibrillation. This study was designed to elucidate inhibitory effects of class I antiarrhythmic drugs on K2P channels. Human K2P2.1 (TREK1) and hK2P3.1 (TASK1) channels were systematically tested for their sensitivity to clinically relevant class IA (ajmaline), class IB (mexiletine), and class IC (propafenone) antiarrhythmic compounds using whole-cell patch clamp and two-electrode voltage clamp electrophysiology in Chinese hamster ovary cells and in Xenopus oocytes. Mexiletine and propafenone inhibited hK2P2.1 (IC50,mexiletine=173µM; IC50,propafenone=7.6µM) and hK2P3.1 channels (IC50,mexiletine=97.3µM; IC50,propafenone=5.1µM) in mammalian cells. Ajmaline did not significantly reduce current amplitudes. K2P channels were blocked in open and closed states, resulting in resting membrane potential depolarization. Open rectification properties of the channels were not affected by class I drugs. In summary, class I antiarrhythmic drugs target cardiac K2P K(+) channels. Blockade of hK2P2.1 and hK2P3.1 potassium currents provides mechanistic evidence to establish cardiac K2P channels as antiarrhythmic drug targets. PMID:24070813

  10. 77 FR 68681 - Amendment of Class E Airspace; Anthony, KS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Anthony, KS AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  11. 77 FR 46284 - Amendment of Class E Airspace; Lemmon, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Lemmon, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  12. 75 FR 41077 - Revision of Class E Airspace; Monterey, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Revision of Class E Airspace; Monterey, CA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace...

  13. 77 FR 68068 - Modification of Class E Airspace; Pullman, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Pullman, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class...

  14. 76 FR 43823 - Revision of Class E Airspace; Yakutat, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Revision of Class E Airspace; Yakutat, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace...

  15. 77 FR 46282 - Amendment of Class E Airspace; Sweetwater, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Sweetwater, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  16. 76 FR 28887 - Revocation of Class E Airspace; Ozark, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ...), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Revocation of Class E Airspace; Ozark, MO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class E airspace...

  17. 78 FR 41685 - Amendment of Class E Airspace; Worthington, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-11

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Worthington, MN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  18. 75 FR 13668 - Amendment of Class E Airspace; Georgetown, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Georgetown, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  19. 76 FR 53049 - Amendment of Class E Airspace; Shelby, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Shelby, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace...

  20. 75 FR 65224 - Amendment of Class E Airspace; Williston, ND

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Williston, ND AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  1. 75 FR 50694 - Modification of Class E Airspace; Astoria, OR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Astoria, OR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend Class...

  2. 75 FR 65228 - Revocation of Class E Airspace; Chilicothe, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Revocation of Class E Airspace; Chilicothe, MO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class...

  3. 76 FR 40597 - Amendment of Class E Airspace; Madison, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Madison, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  4. 76 FR 69608 - Modification of Class E Airspace; Blythe, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Modification of Class E Airspace; Blythe, CA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Blythe, CA, to accommodate aircraft using...

  5. 76 FR 70865 - Modification of Class E Airspace; Driggs, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ...), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Driggs, ID AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class...

  6. 78 FR 50323 - Amendment of Class E Airspace; Lexington, OK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Lexington, OK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  7. 78 FR 57788 - Amendment of Class E Airspace; Everett, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Everett, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace...

  8. 76 FR 8626 - Revision of Class E Airspace; Shungnak, AK

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Revision of Class E Airspace; Shungnak, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace...

  9. 75 FR 13669 - Amendment of Class E Airspace; Dumas, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Dumas, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  10. 78 FR 11980 - Amendment of Class E Airspace; Casper, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Casper, WY AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E...

  11. 76 FR 9219 - Amendment of Class E Airspace; Muncie, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Muncie, IN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  12. 77 FR 56761 - Amendment of Class E Airspace; Kerrville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Kerrville, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  13. 77 FR 68682 - Amendment of Class E Airspace; Guthrie, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Guthrie, IA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  14. 78 FR 27031 - Amendment of Class E Airspace; Kingston, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Kingston, NY AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace...

  15. 75 FR 65225 - Amendment of Class E Airspace; Youngstown, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Youngstown, OH AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  16. 46 CFR 287.6 - Establishment of fund.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the establishment and maintenance of the fund in conformity with the action of the Administration. If... satisfactory in form and substance to the Administration to conform to the action of the Administration as set...) Constructive action not recognized. Constructive deposits, substitutions or withdrawals will not be...

  17. 46 CFR 287.6 - Establishment of fund.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the establishment and maintenance of the fund in conformity with the action of the Administration. If... satisfactory in form and substance to the Administration to conform to the action of the Administration as set...) Constructive action not recognized. Constructive deposits, substitutions or withdrawals will not be...

  18. 46 CFR 287.6 - Establishment of fund.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the establishment and maintenance of the fund in conformity with the action of the Administration. If... satisfactory in form and substance to the Administration to conform to the action of the Administration as set...) Constructive action not recognized. Constructive deposits, substitutions or withdrawals will not be...

  19. 29 CFR 1608.4 - Establishing affirmative action plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... amended, and its implementing regulations, including 41 CFR part 60-2 (known as Revised Order 4), or... Power Co., 401 U.S. 424 (1971). (b) Reasonable basis. If the self analysis shows that one or...

  20. 29 CFR 1608.4 - Establishing affirmative action plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... amended, and its implementing regulations, including 41 CFR part 60-2 (known as Revised Order 4), or... be tailored to solve the problems which were identified in the self analysis, see § 1608.4(a),...